THL1_RS23355 eb9685479893ccb5e736bdcea3d59c54 190 SUPERFAMILY SSF140478 26 177 1.44E-47 T 13-09-2016 IPR023353 LemA-like domain THL1_RS23355 eb9685479893ccb5e736bdcea3d59c54 190 PANTHER PTHR34478:SF1 1 190 3.1E-94 T 13-09-2016 THL1_RS23355 eb9685479893ccb5e736bdcea3d59c54 190 Pfam PF04011 LemA family 8 185 1.3E-59 T 13-09-2016 IPR007156 LemA THL1_RS23355 eb9685479893ccb5e736bdcea3d59c54 190 PANTHER PTHR34478 1 190 3.1E-94 T 13-09-2016 THL1_RS23355 eb9685479893ccb5e736bdcea3d59c54 190 Gene3D G3DSA:1.20.1440.20 16 185 1.6E-55 T 13-09-2016 IPR023353 LemA-like domain THL1_RS10205 4e4c133736b93ee7e449226994192966 345 PANTHER PTHR11019 145 345 8.8E-40 T 13-09-2016 THL1_RS10205 4e4c133736b93ee7e449226994192966 345 Pfam PF12833 Helix-turn-helix domain 262 339 1.0E-14 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS10205 4e4c133736b93ee7e449226994192966 345 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 322 338 7.6E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS10205 4e4c133736b93ee7e449226994192966 345 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 307 322 7.6E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS10205 4e4c133736b93ee7e449226994192966 345 PANTHER PTHR11019:SF52 145 345 8.8E-40 T 13-09-2016 THL1_RS10205 4e4c133736b93ee7e449226994192966 345 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 27 210 3.8E-45 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS10205 4e4c133736b93ee7e449226994192966 345 SUPERFAMILY SSF46689 292 341 2.24E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS10205 4e4c133736b93ee7e449226994192966 345 SMART SM00342 256 338 9.0E-25 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS10205 4e4c133736b93ee7e449226994192966 345 Gene3D G3DSA:1.10.10.60 291 342 8.2E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS06610 17bd286e1085c788d18fe32f5fd12c5c 282 Gene3D G3DSA:1.10.10.60 172 227 1.4E-23 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS06610 17bd286e1085c788d18fe32f5fd12c5c 282 SUPERFAMILY SSF46689 174 224 4.93E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS06610 17bd286e1085c788d18fe32f5fd12c5c 282 SUPERFAMILY SSF51215 31 155 1.57E-21 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS06610 17bd286e1085c788d18fe32f5fd12c5c 282 Gene3D G3DSA:2.60.120.280 30 156 1.0E-15 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS06610 17bd286e1085c788d18fe32f5fd12c5c 282 Gene3D G3DSA:1.10.10.60 228 273 1.2E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS06610 17bd286e1085c788d18fe32f5fd12c5c 282 PANTHER PTHR11019 3 280 3.0E-85 T 13-09-2016 THL1_RS06610 17bd286e1085c788d18fe32f5fd12c5c 282 SUPERFAMILY SSF46689 227 274 9.32E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS06610 17bd286e1085c788d18fe32f5fd12c5c 282 SMART SM00342 190 272 1.6E-30 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS06610 17bd286e1085c788d18fe32f5fd12c5c 282 Pfam PF02311 AraC-like ligand binding domain 19 152 3.4E-24 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS06610 17bd286e1085c788d18fe32f5fd12c5c 282 Pfam PF12833 Helix-turn-helix domain 196 273 2.7E-23 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS06610 17bd286e1085c788d18fe32f5fd12c5c 282 PANTHER PTHR11019:SF105 3 280 3.0E-85 T 13-09-2016 THL1_RS22285 a2a701dec937760369824dd47040d5a4 276 TIGRFAM TIGR00444 mazG: MazG family protein 10 267 5.8E-97 T 13-09-2016 IPR011551 NTP pyrophosphohydrolase MazG THL1_RS22285 a2a701dec937760369824dd47040d5a4 276 SUPERFAMILY SSF101386 4 104 1.31E-22 T 13-09-2016 THL1_RS22285 a2a701dec937760369824dd47040d5a4 276 Gene3D G3DSA:1.10.287.1080 19 71 6.8E-6 T 13-09-2016 THL1_RS22285 a2a701dec937760369824dd47040d5a4 276 Gene3D G3DSA:1.10.287.1080 144 228 4.8E-16 T 13-09-2016 THL1_RS22285 a2a701dec937760369824dd47040d5a4 276 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 27 100 2.5E-24 T 13-09-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core THL1_RS22285 a2a701dec937760369824dd47040d5a4 276 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 178 236 8.6E-12 T 13-09-2016 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core THL1_RS22285 a2a701dec937760369824dd47040d5a4 276 SUPERFAMILY SSF101386 148 245 6.38E-27 T 13-09-2016 THL1_RS22285 a2a701dec937760369824dd47040d5a4 276 PANTHER PTHR30522 1 273 1.7E-122 T 13-09-2016 THL1_RS22285 a2a701dec937760369824dd47040d5a4 276 PANTHER PTHR30522:SF0 1 273 1.7E-122 T 13-09-2016 IPR011551 NTP pyrophosphohydrolase MazG THL1_RS06260 bf77fd958cbc086989b703b119b4c18f 480 PANTHER PTHR12526 351 468 1.7E-108 T 13-09-2016 THL1_RS06260 bf77fd958cbc086989b703b119b4c18f 480 SUPERFAMILY SSF53448 1 280 2.82E-67 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS06260 bf77fd958cbc086989b703b119b4c18f 480 ProSitePatterns PS00018 EF-hand calcium-binding domain. 282 294 - T 13-09-2016 IPR018247 EF-Hand 1, calcium-binding site THL1_RS06260 bf77fd958cbc086989b703b119b4c18f 480 Gene3D G3DSA:2.60.120.10 357 472 4.8E-47 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS06260 bf77fd958cbc086989b703b119b4c18f 480 PANTHER PTHR12526 151 288 1.7E-108 T 13-09-2016 THL1_RS06260 bf77fd958cbc086989b703b119b4c18f 480 Gene3D G3DSA:3.90.550.10 1 270 3.1E-92 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS06260 bf77fd958cbc086989b703b119b4c18f 480 PANTHER PTHR12526:SF387 351 468 1.7E-108 T 13-09-2016 THL1_RS06260 bf77fd958cbc086989b703b119b4c18f 480 Pfam PF01050 Mannose-6-phosphate isomerase 314 464 7.1E-76 T 13-09-2016 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882|UniPathway: UPA00126 THL1_RS06260 bf77fd958cbc086989b703b119b4c18f 480 PANTHER PTHR12526:SF387 151 288 1.7E-108 T 13-09-2016 THL1_RS06260 bf77fd958cbc086989b703b119b4c18f 480 Pfam PF00483 Nucleotidyl transferase 3 286 9.5E-71 T 13-09-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 THL1_RS06260 bf77fd958cbc086989b703b119b4c18f 480 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 1 468 2.6E-224 T 13-09-2016 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882|UniPathway: UPA00126 THL1_RS06260 bf77fd958cbc086989b703b119b4c18f 480 SUPERFAMILY SSF51182 184 469 3.43E-85 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 SMART SM00448 618 732 2.2E-39 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 SMART SM00073 768 862 2.7E-5 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 360 474 1.1E-26 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 SMART SM00388 248 313 6.8E-21 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 SUPERFAMILY SSF55874 302 475 1.57E-42 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 Pfam PF01627 Hpt domain 775 860 2.2E-13 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 473 2.9E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 429 2.9E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 415 2.9E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 454 2.9E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 SMART SM00387 360 476 1.3E-34 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 SUPERFAMILY SSF52172 492 599 8.94E-5 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 Pfam PF00672 HAMP domain 155 222 1.0E-12 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 SUPERFAMILY SSF47384 234 313 3.92E-19 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 PANTHER PTHR24423 168 206 2.5E-140 T 13-09-2016 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 PANTHER PTHR24423 600 737 2.5E-140 T 13-09-2016 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 PANTHER PTHR24423 227 479 2.5E-140 T 13-09-2016 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 Gene3D G3DSA:3.40.50.2300 611 738 3.2E-41 T 13-09-2016 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 Pfam PF00072 Response regulator receiver domain 620 732 1.8E-28 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 SMART SM00304 174 226 3.2E-6 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 312 3.7E-17 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 Gene3D G3DSA:1.20.120.160 753 862 1.2E-23 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 Gene3D G3DSA:3.30.565.10 299 474 4.2E-41 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 Gene3D G3DSA:1.10.287.130 240 298 1.2E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 SUPERFAMILY SSF52172 618 749 1.71E-40 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS06120 4b838d049e328f253fd82730df6c136d 868 SUPERFAMILY SSF47226 752 862 4.45E-22 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS19025 c930ae8b670ed611f03faf5836bddff7 298 Gene3D G3DSA:3.40.190.10 118 243 3.1E-9 T 13-09-2016 THL1_RS19025 c930ae8b670ed611f03faf5836bddff7 298 SMART SM00062 34 284 2.6E-28 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS19025 c930ae8b670ed611f03faf5836bddff7 298 PANTHER PTHR30085:SF2 169 284 1.6E-21 T 13-09-2016 THL1_RS19025 c930ae8b670ed611f03faf5836bddff7 298 PANTHER PTHR30085:SF2 6 147 1.6E-21 T 13-09-2016 THL1_RS19025 c930ae8b670ed611f03faf5836bddff7 298 SUPERFAMILY SSF53850 7 283 9.51E-45 T 13-09-2016 THL1_RS19025 c930ae8b670ed611f03faf5836bddff7 298 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 282 5.1E-35 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS19025 c930ae8b670ed611f03faf5836bddff7 298 Gene3D G3DSA:3.40.190.10 244 283 1.1E-22 T 13-09-2016 THL1_RS19025 c930ae8b670ed611f03faf5836bddff7 298 Gene3D G3DSA:3.40.190.10 31 117 1.1E-22 T 13-09-2016 THL1_RS19025 c930ae8b670ed611f03faf5836bddff7 298 PANTHER PTHR30085 169 284 1.6E-21 T 13-09-2016 THL1_RS19025 c930ae8b670ed611f03faf5836bddff7 298 PANTHER PTHR30085 6 147 1.6E-21 T 13-09-2016 THL1_RS24255 ca2c3dca0279e3dfd58131d8ddb588f8 354 SUPERFAMILY SSF144064 14 350 1.28E-124 T 13-09-2016 THL1_RS24255 ca2c3dca0279e3dfd58131d8ddb588f8 354 Pfam PF05171 Haemin-degrading HemS.ChuX domain 39 167 4.2E-41 T 13-09-2016 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 THL1_RS24255 ca2c3dca0279e3dfd58131d8ddb588f8 354 Pfam PF05171 Haemin-degrading HemS.ChuX domain 220 349 1.4E-38 T 13-09-2016 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 THL1_RS24255 ca2c3dca0279e3dfd58131d8ddb588f8 354 Gene3D G3DSA:3.40.1570.10 15 174 3.9E-5 T 13-09-2016 THL1_RS24255 ca2c3dca0279e3dfd58131d8ddb588f8 354 Gene3D G3DSA:3.40.1570.10 203 334 2.4E-6 T 13-09-2016 THL1_RS03555 191917280815de8b7b317e320ff9299a 228 Pfam PF07650 KH domain 38 111 4.1E-22 T 13-09-2016 IPR004044 K Homology domain, type 2 GO:0003723 THL1_RS03555 191917280815de8b7b317e320ff9299a 228 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 2.3E-98 T 13-09-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 THL1_RS03555 191917280815de8b7b317e320ff9299a 228 Gene3D G3DSA:3.30.300.20 17 107 1.8E-34 T 13-09-2016 IPR015946 K homology domain-like, alpha/beta THL1_RS03555 191917280815de8b7b317e320ff9299a 228 PANTHER PTHR11760 2 222 3.7E-146 T 13-09-2016 THL1_RS03555 191917280815de8b7b317e320ff9299a 228 Gene3D G3DSA:3.30.1140.32 108 207 4.2E-48 T 13-09-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 THL1_RS03555 191917280815de8b7b317e320ff9299a 228 SUPERFAMILY SSF54821 108 206 7.72E-42 T 13-09-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 THL1_RS03555 191917280815de8b7b317e320ff9299a 228 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 13-09-2016 IPR018280 Ribosomal protein S3, conserved site THL1_RS03555 191917280815de8b7b317e320ff9299a 228 SMART SM00322 60 125 3.9E-8 T 13-09-2016 IPR004087 K Homology domain GO:0003676 THL1_RS03555 191917280815de8b7b317e320ff9299a 228 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 39.852 T 13-09-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 THL1_RS03555 191917280815de8b7b317e320ff9299a 228 PANTHER PTHR11760:SF19 2 222 3.7E-146 T 13-09-2016 THL1_RS03555 191917280815de8b7b317e320ff9299a 228 SUPERFAMILY SSF54814 2 106 1.73E-38 T 13-09-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 THL1_RS03555 191917280815de8b7b317e320ff9299a 228 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 2.8E-42 T 13-09-2016 THL1_RS00670 48184dc4f5293de50c77b465e8681875 335 Pfam PF12833 Helix-turn-helix domain 254 331 9.6E-19 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS00670 48184dc4f5293de50c77b465e8681875 335 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 314 330 3.4E-8 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS00670 48184dc4f5293de50c77b465e8681875 335 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 299 314 3.4E-8 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS00670 48184dc4f5293de50c77b465e8681875 335 SMART SM00342 248 330 6.4E-26 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS00670 48184dc4f5293de50c77b465e8681875 335 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 22 205 7.7E-52 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS00670 48184dc4f5293de50c77b465e8681875 335 PANTHER PTHR11019 190 199 3.0E-31 T 13-09-2016 THL1_RS00670 48184dc4f5293de50c77b465e8681875 335 PANTHER PTHR11019 222 330 3.0E-31 T 13-09-2016 THL1_RS00670 48184dc4f5293de50c77b465e8681875 335 PANTHER PTHR11019:SF52 222 330 3.0E-31 T 13-09-2016 THL1_RS00670 48184dc4f5293de50c77b465e8681875 335 PANTHER PTHR11019:SF52 190 199 3.0E-31 T 13-09-2016 THL1_RS00670 48184dc4f5293de50c77b465e8681875 335 SUPERFAMILY SSF46689 284 332 2.11E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS00670 48184dc4f5293de50c77b465e8681875 335 Gene3D G3DSA:1.10.10.60 284 331 5.6E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS00385 2be60be6b5997e1324c1a3161df84b57 210 Gene3D G3DSA:3.40.30.10 28 209 4.4E-59 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS00385 2be60be6b5997e1324c1a3161df84b57 210 PANTHER PTHR35891:SF2 1 210 6.8E-79 T 13-09-2016 THL1_RS00385 2be60be6b5997e1324c1a3161df84b57 210 SUPERFAMILY SSF52833 26 202 1.34E-45 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS00385 2be60be6b5997e1324c1a3161df84b57 210 PANTHER PTHR35891 1 210 6.8E-79 T 13-09-2016 THL1_RS00385 2be60be6b5997e1324c1a3161df84b57 210 PIRSF PIRSF001488 1 210 2.5E-72 T 13-09-2016 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL THL1_RS00385 2be60be6b5997e1324c1a3161df84b57 210 ProSitePatterns PS00194 Thioredoxin family active site. 49 67 - T 13-09-2016 IPR017937 Thioredoxin, conserved site GO:0045454 THL1_RS00385 2be60be6b5997e1324c1a3161df84b57 210 Pfam PF01323 DSBA-like thioredoxin domain 97 183 3.2E-15 T 13-09-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 THL1_RS05585 553927c37c5f7117967f131cae4178b4 290 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 14 285 4.6E-92 T 13-09-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS05585 553927c37c5f7117967f131cae4178b4 290 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 91 102 - T 13-09-2016 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS05585 553927c37c5f7117967f131cae4178b4 290 PANTHER PTHR21091:SF18 2 225 1.5E-86 T 13-09-2016 THL1_RS05585 553927c37c5f7117967f131cae4178b4 290 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 13 234 36.908 T 13-09-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS05585 553927c37c5f7117967f131cae4178b4 290 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 13 214 6.9E-30 T 13-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 THL1_RS05585 553927c37c5f7117967f131cae4178b4 290 PANTHER PTHR21091 2 225 1.5E-86 T 13-09-2016 THL1_RS05585 553927c37c5f7117967f131cae4178b4 290 Gene3D G3DSA:3.30.950.10 122 235 1.4E-40 T 13-09-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 THL1_RS05585 553927c37c5f7117967f131cae4178b4 290 PIRSF PIRSF005917 3 289 1.4E-102 T 13-09-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS05585 553927c37c5f7117967f131cae4178b4 290 Gene3D G3DSA:3.40.1010.10 12 121 2.3E-16 T 13-09-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 THL1_RS05585 553927c37c5f7117967f131cae4178b4 290 SUPERFAMILY SSF53790 12 232 2.62E-81 T 13-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 THL1_RS02540 7c3f83cffd005ba4500e29d0fe703b49 71 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.2E-16 T 13-09-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 THL1_RS02540 7c3f83cffd005ba4500e29d0fe703b49 71 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.2E-16 T 13-09-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 THL1_RS02540 7c3f83cffd005ba4500e29d0fe703b49 71 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.2E-16 T 13-09-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 THL1_RS02540 7c3f83cffd005ba4500e29d0fe703b49 71 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.2E-16 T 13-09-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 THL1_RS02540 7c3f83cffd005ba4500e29d0fe703b49 71 Pfam PF01165 Ribosomal protein S21 4 56 2.3E-22 T 13-09-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 THL1_RS02540 7c3f83cffd005ba4500e29d0fe703b49 71 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 44 2.0E-9 T 13-09-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 THL1_RS02540 7c3f83cffd005ba4500e29d0fe703b49 71 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 3.7E-25 T 13-09-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 THL1_RS02540 7c3f83cffd005ba4500e29d0fe703b49 71 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 13-09-2016 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS02540 7c3f83cffd005ba4500e29d0fe703b49 71 PANTHER PTHR21109 1 71 2.6E-24 T 13-09-2016 THL1_RS02540 7c3f83cffd005ba4500e29d0fe703b49 71 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 20.978 T 13-09-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 THL1_RS01515 867dcf481804ffb5c5c53f4e0358defc 320 SUPERFAMILY SSF56059 124 310 4.42E-56 T 13-09-2016 THL1_RS01515 867dcf481804ffb5c5c53f4e0358defc 320 Gene3D G3DSA:3.40.50.20 4 130 5.5E-52 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS01515 867dcf481804ffb5c5c53f4e0358defc 320 Hamap MF_00162 Glutathione synthetase [gshB]. 1 317 171.633 T 13-09-2016 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3|UniPathway: UPA00142 THL1_RS01515 867dcf481804ffb5c5c53f4e0358defc 320 TIGRFAM TIGR01380 glut_syn: glutathione synthase 4 311 3.8E-134 T 13-09-2016 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3|UniPathway: UPA00142 THL1_RS01515 867dcf481804ffb5c5c53f4e0358defc 320 Gene3D G3DSA:3.30.470.20 193 300 5.7E-49 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS01515 867dcf481804ffb5c5c53f4e0358defc 320 SUPERFAMILY SSF52440 3 123 1.9E-43 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS01515 867dcf481804ffb5c5c53f4e0358defc 320 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 4 121 1.1E-43 T 13-09-2016 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3|UniPathway: UPA00142 THL1_RS01515 867dcf481804ffb5c5c53f4e0358defc 320 PANTHER PTHR21621 1 317 9.9E-157 T 13-09-2016 THL1_RS01515 867dcf481804ffb5c5c53f4e0358defc 320 PANTHER PTHR21621:SF4 1 317 9.9E-157 T 13-09-2016 THL1_RS01515 867dcf481804ffb5c5c53f4e0358defc 320 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 125 297 4.5E-77 T 13-09-2016 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3|UniPathway: UPA00142 THL1_RS01515 867dcf481804ffb5c5c53f4e0358defc 320 Gene3D G3DSA:3.30.1490.20 138 192 6.0E-27 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS10985 f8ca30ddd2cfe7c96dfaf9c66e9ac796 171 Hamap MF_00405 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase [fabA]. 1 171 52.15 T 13-09-2016 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 THL1_RS10985 f8ca30ddd2cfe7c96dfaf9c66e9ac796 171 Pfam PF07977 FabA-like domain 28 158 1.5E-52 T 13-09-2016 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 THL1_RS10985 f8ca30ddd2cfe7c96dfaf9c66e9ac796 171 SUPERFAMILY SSF54637 2 168 2.4E-58 T 13-09-2016 IPR029069 HotDog domain THL1_RS10985 f8ca30ddd2cfe7c96dfaf9c66e9ac796 171 TIGRFAM TIGR01749 fabA: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA 3 171 8.5E-98 T 13-09-2016 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 THL1_RS10985 f8ca30ddd2cfe7c96dfaf9c66e9ac796 171 Gene3D G3DSA:3.10.129.10 2 166 1.1E-59 T 13-09-2016 IPR029069 HotDog domain THL1_RS15665 08edd8c65cc63213f0718a210f8f90b9 457 Gene3D G3DSA:3.10.20.70 9 119 5.8E-10 T 13-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS15665 08edd8c65cc63213f0718a210f8f90b9 457 PANTHER PTHR20852 10 457 5.6E-167 T 13-09-2016 THL1_RS15665 08edd8c65cc63213f0718a210f8f90b9 457 Pfam PF00120 Glutamine synthetase, catalytic domain 119 452 1.8E-108 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS15665 08edd8c65cc63213f0718a210f8f90b9 457 SMART SM01230 118 374 2.7E-103 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS15665 08edd8c65cc63213f0718a210f8f90b9 457 PANTHER PTHR20852:SF35 10 457 5.6E-167 T 13-09-2016 THL1_RS15665 08edd8c65cc63213f0718a210f8f90b9 457 SUPERFAMILY SSF54368 8 113 2.49E-19 T 13-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS15665 08edd8c65cc63213f0718a210f8f90b9 457 SUPERFAMILY SSF55931 118 455 2.65E-108 T 13-09-2016 THL1_RS15665 08edd8c65cc63213f0718a210f8f90b9 457 Gene3D G3DSA:3.30.590.10 121 443 1.9E-98 T 13-09-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SUPERFAMILY SSF55785 771 893 2.79E-24 T 13-09-2016 IPR000014 PAS domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Pfam PF13426 PAS domain 1224 1321 1.2E-20 T 13-09-2016 IPR000014 PAS domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SMART SM00448 1776 1888 1.8E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1333 1489 3.1E-49 T 13-09-2016 IPR000160 GGDEF domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Gene3D G3DSA:3.30.450.20 493 603 2.3E-20 T 13-09-2016 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Gene3D G3DSA:3.30.450.20 779 893 1.1E-24 T 13-09-2016 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Gene3D G3DSA:3.20.20.450 1508 1758 1.7E-97 T 13-09-2016 IPR001633 EAL domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Pfam PF00072 Response regulator receiver domain 1779 1888 1.9E-21 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Pfam PF00989 PAS fold 791 893 5.2E-11 T 13-09-2016 IPR013767 PAS fold GO:0006355 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Pfam PF00989 PAS fold 1100 1170 5.4E-6 T 13-09-2016 IPR013767 PAS fold GO:0006355 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Pfam PF13185 GAF domain 629 771 3.8E-15 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Pfam PF13185 GAF domain 932 1077 1.3E-9 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SUPERFAMILY SSF52172 1777 1895 4.98E-30 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Pfam PF08447 PAS fold 520 588 1.4E-8 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Gene3D G3DSA:3.30.450.40 604 778 3.7E-23 T 13-09-2016 IPR029016 GAF domain-like THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Gene3D G3DSA:3.30.450.40 907 1091 2.4E-18 T 13-09-2016 IPR029016 GAF domain-like THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SUPERFAMILY SSF55073 1338 1496 1.02E-50 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Pfam PF00563 EAL domain 1510 1745 1.4E-72 T 13-09-2016 IPR001633 EAL domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SUPERFAMILY SSF55781 630 783 6.32E-26 T 13-09-2016 IPR029016 GAF domain-like THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SMART SM00086 1280 1322 1.6E-11 T 13-09-2016 IPR001610 PAC motif THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SMART SM00086 855 896 2.6 T 13-09-2016 IPR001610 PAC motif THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SMART SM00086 568 606 33.0 T 13-09-2016 IPR001610 PAC motif THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 PANTHER PTHR33121 1378 1385 7.9E-88 T 13-09-2016 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 PANTHER PTHR33121 1454 1781 7.9E-88 T 13-09-2016 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SMART SM00065 624 780 1.2E-10 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SMART SM00065 932 1086 5.7E-8 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SUPERFAMILY SSF55781 914 1104 1.33E-23 T 13-09-2016 IPR029016 GAF domain-like THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SUPERFAMILY SSF55785 1088 1195 3.91E-12 T 13-09-2016 IPR000014 PAS domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SUPERFAMILY SSF141868 1510 1761 1.44E-92 T 13-09-2016 IPR001633 EAL domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SUPERFAMILY SSF55785 1213 1322 6.14E-28 T 13-09-2016 IPR000014 PAS domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Gene3D G3DSA:3.40.50.2300 1777 1907 8.3E-30 T 13-09-2016 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SMART SM00052 1504 1750 7.7E-119 T 13-09-2016 IPR001633 EAL domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SUPERFAMILY SSF55785 488 604 1.33E-17 T 13-09-2016 IPR000014 PAS domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Gene3D G3DSA:3.30.450.20 1217 1322 8.2E-36 T 13-09-2016 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 500 610 9.3E-17 T 13-09-2016 IPR000014 PAS domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 780 903 6.7E-19 T 13-09-2016 IPR000014 PAS domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 1230 1329 3.7E-18 T 13-09-2016 IPR000014 PAS domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SMART SM00091 496 562 1.4E-10 T 13-09-2016 IPR000014 PAS domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SMART SM00091 784 850 4.3E-9 T 13-09-2016 IPR000014 PAS domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SMART SM00091 1097 1163 3.1E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SMART SM00091 1205 1274 3.7E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 SMART SM00267 1322 1494 7.5E-69 T 13-09-2016 IPR000160 GGDEF domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1330 1492 5.7E-46 T 13-09-2016 IPR000160 GGDEF domain THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 PANTHER PTHR33121:SF13 1378 1385 7.9E-88 T 13-09-2016 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 PANTHER PTHR33121:SF13 1454 1781 7.9E-88 T 13-09-2016 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Gene3D G3DSA:3.30.450.20 1092 1195 3.7E-13 T 13-09-2016 THL1_RS03125 bfb37f6fd327806877572a38b4c02b10 1913 Gene3D G3DSA:3.30.70.270 1335 1502 1.5E-59 T 13-09-2016 THL1_RS08470 b57c75d9ba3472e4807a366dc8ccf1df 93 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 30 50 - T 13-09-2016 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site THL1_RS08470 b57c75d9ba3472e4807a366dc8ccf1df 93 Gene3D G3DSA:3.10.50.40 3 93 8.6E-35 T 13-09-2016 THL1_RS08470 b57c75d9ba3472e4807a366dc8ccf1df 93 PANTHER PTHR10657 3 93 1.6E-40 T 13-09-2016 THL1_RS08470 b57c75d9ba3472e4807a366dc8ccf1df 93 Pfam PF13616 PPIC-type PPIASE domain 6 91 1.1E-21 T 13-09-2016 THL1_RS08470 b57c75d9ba3472e4807a366dc8ccf1df 93 SUPERFAMILY SSF54534 3 89 1.11E-28 T 13-09-2016 THL1_RS18720 df0cb637f64f59bc7eab6bfd8b7ac565 460 PANTHER PTHR11206 14 457 1.6E-204 T 13-09-2016 THL1_RS18720 df0cb637f64f59bc7eab6bfd8b7ac565 460 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 423 2.1E-102 T 13-09-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 THL1_RS18720 df0cb637f64f59bc7eab6bfd8b7ac565 460 PIRSF PIRSF006603 9 459 2.7E-65 T 13-09-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 THL1_RS18720 df0cb637f64f59bc7eab6bfd8b7ac565 460 PANTHER PTHR11206:SF153 14 457 1.6E-204 T 13-09-2016 THL1_RS18720 df0cb637f64f59bc7eab6bfd8b7ac565 460 Pfam PF01554 MatE 28 187 4.9E-38 T 13-09-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 THL1_RS18720 df0cb637f64f59bc7eab6bfd8b7ac565 460 Pfam PF01554 MatE 254 414 3.3E-35 T 13-09-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 THL1_RS23745 8181a4461aa74461de8b9a11d79453f5 391 PANTHER PTHR18919 1 391 1.8E-229 T 13-09-2016 THL1_RS23745 8181a4461aa74461de8b9a11d79453f5 391 Gene3D G3DSA:3.40.47.10 275 390 4.7E-55 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS23745 8181a4461aa74461de8b9a11d79453f5 391 Gene3D G3DSA:3.40.47.10 142 193 4.7E-55 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS23745 8181a4461aa74461de8b9a11d79453f5 391 ProSitePatterns PS00099 Thiolases active site. 372 385 - T 13-09-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 THL1_RS23745 8181a4461aa74461de8b9a11d79453f5 391 PANTHER PTHR18919:SF110 1 391 1.8E-229 T 13-09-2016 THL1_RS23745 8181a4461aa74461de8b9a11d79453f5 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 13-09-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 THL1_RS23745 8181a4461aa74461de8b9a11d79453f5 391 Pfam PF00108 Thiolase, N-terminal domain 4 260 6.3E-88 T 13-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THL1_RS23745 8181a4461aa74461de8b9a11d79453f5 391 SUPERFAMILY SSF53901 269 390 1.46E-39 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS23745 8181a4461aa74461de8b9a11d79453f5 391 Gene3D G3DSA:3.40.47.10 3 123 7.9E-71 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS23745 8181a4461aa74461de8b9a11d79453f5 391 Gene3D G3DSA:3.40.47.10 194 274 7.9E-71 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS23745 8181a4461aa74461de8b9a11d79453f5 391 PIRSF PIRSF000429 1 391 1.7E-110 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS23745 8181a4461aa74461de8b9a11d79453f5 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 389 2.3E-127 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS23745 8181a4461aa74461de8b9a11d79453f5 391 Pfam PF02803 Thiolase, C-terminal domain 268 389 3.6E-40 T 13-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THL1_RS23745 8181a4461aa74461de8b9a11d79453f5 391 SUPERFAMILY SSF53901 3 268 1.53E-80 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS24585 44e047eb302017b8600dc033b1b48eb8 372 Gene3D G3DSA:3.40.50.300 7 249 1.0E-75 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24585 44e047eb302017b8600dc033b1b48eb8 372 PANTHER PTHR24220:SF150 12 257 1.1E-128 T 13-09-2016 THL1_RS24585 44e047eb302017b8600dc033b1b48eb8 372 SUPERFAMILY SSF52540 11 254 3.59E-84 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24585 44e047eb302017b8600dc033b1b48eb8 372 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS24585 44e047eb302017b8600dc033b1b48eb8 372 Pfam PF00005 ABC transporter 31 173 9.0E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS24585 44e047eb302017b8600dc033b1b48eb8 372 PANTHER PTHR24220 12 257 1.1E-128 T 13-09-2016 THL1_RS24585 44e047eb302017b8600dc033b1b48eb8 372 Pfam PF08402 TOBE domain 289 366 9.7E-9 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS24585 44e047eb302017b8600dc033b1b48eb8 372 SMART SM00382 40 223 2.4E-16 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS24585 44e047eb302017b8600dc033b1b48eb8 372 SUPERFAMILY SSF50331 250 371 6.23E-10 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS24585 44e047eb302017b8600dc033b1b48eb8 372 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 46 345 4.4E-109 T 13-09-2016 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 THL1_RS04065 0d91747cdb88aa817b9f653b4ac5ae11 219 PANTHER PTHR30353:SF0 1 216 2.5E-86 T 13-09-2016 THL1_RS04065 0d91747cdb88aa817b9f653b4ac5ae11 219 PANTHER PTHR30353 1 216 2.5E-86 T 13-09-2016 IPR032818 DedA family THL1_RS04065 0d91747cdb88aa817b9f653b4ac5ae11 219 Pfam PF09335 SNARE associated Golgi protein 47 171 3.2E-23 T 13-09-2016 IPR032816 SNARE associated Golgi protein THL1_RS11375 f33b0718dd956c742c09f25cd2d60e8f 239 Pfam PF00117 Glutamine amidotransferase class-I 92 191 2.0E-10 T 13-09-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 THL1_RS11375 f33b0718dd956c742c09f25cd2d60e8f 239 PANTHER PTHR11922 1 198 5.2E-38 T 13-09-2016 THL1_RS11375 f33b0718dd956c742c09f25cd2d60e8f 239 Gene3D G3DSA:3.40.50.880 16 226 3.0E-42 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS11375 f33b0718dd956c742c09f25cd2d60e8f 239 SUPERFAMILY SSF52317 2 228 1.68E-42 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS11375 f33b0718dd956c742c09f25cd2d60e8f 239 PANTHER PTHR11922:SF34 1 198 5.2E-38 T 13-09-2016 THL1_RS08055 57bba8c6e0b16e3526db3ee65ad333d9 454 PANTHER PTHR20852:SF7 7 453 1.9E-130 T 13-09-2016 THL1_RS08055 57bba8c6e0b16e3526db3ee65ad333d9 454 Pfam PF00120 Glutamine synthetase, catalytic domain 118 450 9.3E-108 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS08055 57bba8c6e0b16e3526db3ee65ad333d9 454 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 253 268 - T 13-09-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS08055 57bba8c6e0b16e3526db3ee65ad333d9 454 SMART SM01230 117 372 3.2E-98 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS08055 57bba8c6e0b16e3526db3ee65ad333d9 454 PANTHER PTHR20852 7 453 1.9E-130 T 13-09-2016 THL1_RS08055 57bba8c6e0b16e3526db3ee65ad333d9 454 SUPERFAMILY SSF55931 119 452 5.49E-104 T 13-09-2016 THL1_RS08055 57bba8c6e0b16e3526db3ee65ad333d9 454 Gene3D G3DSA:3.30.590.10 120 440 3.1E-94 T 13-09-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 THL1_RS08055 57bba8c6e0b16e3526db3ee65ad333d9 454 SUPERFAMILY SSF54368 6 114 3.01E-7 T 13-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 Pfam PF13188 PAS domain 76 130 1.8E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 SUPERFAMILY SSF55874 264 393 1.27E-31 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 Gene3D G3DSA:1.10.287.130 176 243 5.8E-8 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 Pfam PF00512 His Kinase A (phospho-acceptor) domain 181 245 9.3E-13 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 SMART SM00388 181 247 5.5E-13 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 Gene3D G3DSA:3.30.565.10 253 395 7.8E-31 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 PANTHER PTHR24423:SF554 62 396 4.7E-76 T 13-09-2016 THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 SMART SM00387 287 393 1.6E-23 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 SUPERFAMILY SSF55785 75 153 1.85E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 Gene3D G3DSA:3.30.450.20 70 134 1.5E-8 T 13-09-2016 THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 291 391 2.0E-18 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 SUPERFAMILY SSF47384 174 245 4.71E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 SMART SM00091 75 138 2.4E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 390 9.1E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 PRINTS PR00344 Bacterial sensor protein C-terminal signature 324 338 9.1E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 371 9.1E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 352 9.1E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS19625 4ff4e89604ad4f446fe19f3a23b0040d 401 PANTHER PTHR24423 62 396 4.7E-76 T 13-09-2016 THL1_RS17965 0d76e97fb95f76a06eca5dc7e86adf04 111 PANTHER PTHR36455 2 97 4.9E-16 T 13-09-2016 THL1_RS17965 0d76e97fb95f76a06eca5dc7e86adf04 111 Pfam PF05717 IS66 Orf2 like protein 6 102 1.5E-28 T 13-09-2016 IPR008878 Transposase IS66, Orf2 THL1_RS17965 0d76e97fb95f76a06eca5dc7e86adf04 111 PANTHER PTHR36455:SF1 2 97 4.9E-16 T 13-09-2016 THL1_RS16060 0d76e97fb95f76a06eca5dc7e86adf04 111 PANTHER PTHR36455 2 97 4.9E-16 T 13-09-2016 THL1_RS16060 0d76e97fb95f76a06eca5dc7e86adf04 111 Pfam PF05717 IS66 Orf2 like protein 6 102 1.5E-28 T 13-09-2016 IPR008878 Transposase IS66, Orf2 THL1_RS16060 0d76e97fb95f76a06eca5dc7e86adf04 111 PANTHER PTHR36455:SF1 2 97 4.9E-16 T 13-09-2016 THL1_RS27650 0d76e97fb95f76a06eca5dc7e86adf04 111 PANTHER PTHR36455 2 97 4.9E-16 T 13-09-2016 THL1_RS27650 0d76e97fb95f76a06eca5dc7e86adf04 111 Pfam PF05717 IS66 Orf2 like protein 6 102 1.5E-28 T 13-09-2016 IPR008878 Transposase IS66, Orf2 THL1_RS27650 0d76e97fb95f76a06eca5dc7e86adf04 111 PANTHER PTHR36455:SF1 2 97 4.9E-16 T 13-09-2016 THL1_RS00030 0d76e97fb95f76a06eca5dc7e86adf04 111 PANTHER PTHR36455 2 97 4.9E-16 T 13-09-2016 THL1_RS00030 0d76e97fb95f76a06eca5dc7e86adf04 111 Pfam PF05717 IS66 Orf2 like protein 6 102 1.5E-28 T 13-09-2016 IPR008878 Transposase IS66, Orf2 THL1_RS00030 0d76e97fb95f76a06eca5dc7e86adf04 111 PANTHER PTHR36455:SF1 2 97 4.9E-16 T 13-09-2016 THL1_RS01910 6f71895097f2247a361935eff2e3b479 346 Pfam PF01212 Beta-eliminating lyase 7 297 1.1E-78 T 13-09-2016 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 THL1_RS01910 6f71895097f2247a361935eff2e3b479 346 Gene3D G3DSA:3.40.640.10 7 253 3.3E-68 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS01910 6f71895097f2247a361935eff2e3b479 346 PANTHER PTHR10289 1 344 2.7E-166 T 13-09-2016 THL1_RS01910 6f71895097f2247a361935eff2e3b479 346 SUPERFAMILY SSF53383 7 341 2.45E-102 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS01910 6f71895097f2247a361935eff2e3b479 346 PIRSF PIRSF038940 5 346 5.2E-141 T 13-09-2016 IPR026273 Low specificity L-threonine aldolase GO:0004793|GO:0006567 KEGG: 00260+4.1.2.48 THL1_RS01910 6f71895097f2247a361935eff2e3b479 346 PANTHER PTHR10289:SF8 1 344 2.7E-166 T 13-09-2016 THL1_RS01910 6f71895097f2247a361935eff2e3b479 346 Gene3D G3DSA:3.90.1150.10 257 342 4.0E-15 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS28360 4e57bd4a5b6d542e55f8fc7347366017 435 PANTHER PTHR23508 12 435 1.4E-269 T 13-09-2016 THL1_RS28360 4e57bd4a5b6d542e55f8fc7347366017 435 TIGRFAM TIGR00883 2A0106: MFS transporter, metabolite:H+ symporter (MHS) family protein 29 415 2.8E-135 T 13-09-2016 IPR004736 Citrate-proton symport GO:0005215|GO:0006810|GO:0016021 THL1_RS28360 4e57bd4a5b6d542e55f8fc7347366017 435 ProSitePatterns PS00216 Sugar transport proteins signature 1. 299 316 - T 13-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 THL1_RS28360 4e57bd4a5b6d542e55f8fc7347366017 435 Pfam PF00083 Sugar (and other) transporter 27 232 9.3E-29 T 13-09-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 THL1_RS28360 4e57bd4a5b6d542e55f8fc7347366017 435 SUPERFAMILY SSF103473 19 429 5.62E-69 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS28360 4e57bd4a5b6d542e55f8fc7347366017 435 ProSitePatterns PS00217 Sugar transport proteins signature 2. 132 157 - T 13-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 THL1_RS28360 4e57bd4a5b6d542e55f8fc7347366017 435 Gene3D G3DSA:1.20.1250.20 232 429 2.1E-23 T 13-09-2016 THL1_RS28360 4e57bd4a5b6d542e55f8fc7347366017 435 Gene3D G3DSA:1.20.1250.20 21 231 3.0E-27 T 13-09-2016 THL1_RS28360 4e57bd4a5b6d542e55f8fc7347366017 435 Pfam PF07690 Major Facilitator Superfamily 257 428 4.5E-10 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS28360 4e57bd4a5b6d542e55f8fc7347366017 435 PANTHER PTHR23508:SF4 12 435 1.4E-269 T 13-09-2016 THL1_RS07490 513c4e2879eab499aabea254a01bcc3e 303 Hamap MF_01576 Bifunctional protein FolD [folD]. 7 289 38.227 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07490 513c4e2879eab499aabea254a01bcc3e 303 Gene3D G3DSA:3.40.192.10 11 142 1.3E-47 T 13-09-2016 THL1_RS07490 513c4e2879eab499aabea254a01bcc3e 303 SUPERFAMILY SSF51735 126 287 9.11E-52 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07490 513c4e2879eab499aabea254a01bcc3e 303 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 262 280 3.4E-81 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07490 513c4e2879eab499aabea254a01bcc3e 303 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 113 134 3.4E-81 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07490 513c4e2879eab499aabea254a01bcc3e 303 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 37 59 3.4E-81 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07490 513c4e2879eab499aabea254a01bcc3e 303 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 245 261 3.4E-81 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07490 513c4e2879eab499aabea254a01bcc3e 303 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 158 178 3.4E-81 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07490 513c4e2879eab499aabea254a01bcc3e 303 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 207 236 3.4E-81 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07490 513c4e2879eab499aabea254a01bcc3e 303 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 78 105 3.4E-81 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07490 513c4e2879eab499aabea254a01bcc3e 303 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 266 274 - T 13-09-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07490 513c4e2879eab499aabea254a01bcc3e 303 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 79 104 - T 13-09-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07490 513c4e2879eab499aabea254a01bcc3e 303 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 127 287 8.6E-68 T 13-09-2016 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07490 513c4e2879eab499aabea254a01bcc3e 303 Gene3D G3DSA:3.40.50.720 143 270 1.8E-53 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07490 513c4e2879eab499aabea254a01bcc3e 303 SUPERFAMILY SSF53223 7 125 1.92E-38 T 13-09-2016 THL1_RS07490 513c4e2879eab499aabea254a01bcc3e 303 PANTHER PTHR10025 1 285 1.6E-148 T 13-09-2016 THL1_RS07490 513c4e2879eab499aabea254a01bcc3e 303 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 9 124 4.6E-39 T 13-09-2016 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS06265 5f88c7a7ccf983811b5a1d6b69c35d3a 214 ProDom PD022759 ALGINATE BIOSYNTHESIS ALGF PRECURSOR SIGNAL PERIPLASMIC TRANSFERASE O-ACETYLTRANSFERASE 33 214 7.0E-77 T 13-09-2016 THL1_RS06265 5f88c7a7ccf983811b5a1d6b69c35d3a 214 Pfam PF11182 Alginate O-acetyl transferase AlgF 16 193 1.1E-80 T 13-09-2016 THL1_RS05750 c69a78793609395f3d6a94f143e54d5e 111 Gene3D G3DSA:1.10.10.10 11 92 6.5E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS05750 c69a78793609395f3d6a94f143e54d5e 111 PANTHER PTHR10815 10 106 2.5E-28 T 13-09-2016 THL1_RS05750 c69a78793609395f3d6a94f143e54d5e 111 PANTHER PTHR10815:SF2 10 106 2.5E-28 T 13-09-2016 THL1_RS05750 c69a78793609395f3d6a94f143e54d5e 111 SUPERFAMILY SSF46767 11 91 8.24E-20 T 13-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 THL1_RS05750 c69a78793609395f3d6a94f143e54d5e 111 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 11 90 7.9E-19 T 13-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 THL1_RS20045 9d65a9088307860a13b52824272e5de1 213 Pfam PF13181 Tetratricopeptide repeat 137 155 0.14 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS20045 9d65a9088307860a13b52824272e5de1 213 Gene3D G3DSA:1.25.40.10 67 188 1.4E-13 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS20045 9d65a9088307860a13b52824272e5de1 213 SUPERFAMILY SSF48452 39 180 1.26E-14 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS16670 4acadca0956e541d21f6dc37261d0f29 515 Pfam PF03050 Transposase IS66 family 185 466 5.2E-105 T 13-09-2016 IPR004291 Transposase, IS66 THL1_RS16670 4acadca0956e541d21f6dc37261d0f29 515 Pfam PF13007 Transposase C of IS166 homeodomain 49 122 2.0E-14 T 13-09-2016 IPR024463 Transposase TnpC, homeodomain THL1_RS16670 4acadca0956e541d21f6dc37261d0f29 515 Pfam PF13005 zinc-finger binding domain of transposase IS66 129 171 8.7E-14 T 13-09-2016 IPR024474 Zinc-finger binding domain of transposase IS66 THL1_RS16670 4acadca0956e541d21f6dc37261d0f29 515 PANTHER PTHR33678:SF1 22 509 9.8E-99 T 13-09-2016 THL1_RS16670 4acadca0956e541d21f6dc37261d0f29 515 Pfam PF13817 IS66 C-terminal element 473 510 2.7E-16 T 13-09-2016 THL1_RS16670 4acadca0956e541d21f6dc37261d0f29 515 PANTHER PTHR33678 22 509 9.8E-99 T 13-09-2016 THL1_RS01425 ca8388a0373ad3953dd4c85a230bebef 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 292 7.7E-18 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01425 ca8388a0373ad3953dd4c85a230bebef 304 SUPERFAMILY SSF161098 14 294 3.14E-54 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01425 ca8388a0373ad3953dd4c85a230bebef 304 Gene3D G3DSA:1.10.3720.10 9 291 1.5E-50 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01425 ca8388a0373ad3953dd4c85a230bebef 304 PANTHER PTHR30193 1 297 1.3E-118 T 13-09-2016 THL1_RS01425 ca8388a0373ad3953dd4c85a230bebef 304 PANTHER PTHR30193:SF10 1 297 1.3E-118 T 13-09-2016 THL1_RS03640 6612f1505ad78f0c94ed2173877365bd 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 9.2E-56 T 13-09-2016 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03640 6612f1505ad78f0c94ed2173877365bd 129 Pfam PF00411 Ribosomal protein S11 19 128 2.2E-51 T 13-09-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 THL1_RS03640 6612f1505ad78f0c94ed2173877365bd 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 32.706 T 13-09-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 THL1_RS03640 6612f1505ad78f0c94ed2173877365bd 129 SUPERFAMILY SSF53137 15 129 2.09E-47 T 13-09-2016 THL1_RS03640 6612f1505ad78f0c94ed2173877365bd 129 PIRSF PIRSF002131 1 129 1.4E-53 T 13-09-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 THL1_RS03640 6612f1505ad78f0c94ed2173877365bd 129 Gene3D G3DSA:3.30.420.80 9 129 6.1E-54 T 13-09-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 THL1_RS03640 6612f1505ad78f0c94ed2173877365bd 129 PANTHER PTHR11759 11 129 6.9E-72 T 13-09-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 THL1_RS03640 6612f1505ad78f0c94ed2173877365bd 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 13-09-2016 IPR018102 Ribosomal S11, conserved site THL1_RS22945 b0969ffc7d82126178ac94d825636b5c 303 SUPERFAMILY SSF53850 87 296 1.54E-37 T 13-09-2016 THL1_RS22945 b0969ffc7d82126178ac94d825636b5c 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 7.5E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS22945 b0969ffc7d82126178ac94d825636b5c 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 7.5E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS22945 b0969ffc7d82126178ac94d825636b5c 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 7.5E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS22945 b0969ffc7d82126178ac94d825636b5c 303 Gene3D G3DSA:3.40.190.10 91 177 1.7E-18 T 13-09-2016 THL1_RS22945 b0969ffc7d82126178ac94d825636b5c 303 SUPERFAMILY SSF46785 1 112 3.29E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS22945 b0969ffc7d82126178ac94d825636b5c 303 PANTHER PTHR30346 2 295 1.2E-85 T 13-09-2016 THL1_RS22945 b0969ffc7d82126178ac94d825636b5c 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.9E-21 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS22945 b0969ffc7d82126178ac94d825636b5c 303 PANTHER PTHR30346:SF13 2 295 1.2E-85 T 13-09-2016 THL1_RS22945 b0969ffc7d82126178ac94d825636b5c 303 Gene3D G3DSA:1.10.10.10 1 83 2.2E-28 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS22945 b0969ffc7d82126178ac94d825636b5c 303 Pfam PF03466 LysR substrate binding domain 88 295 4.6E-42 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS22945 b0969ffc7d82126178ac94d825636b5c 303 Gene3D G3DSA:3.40.190.10 178 264 1.8E-30 T 13-09-2016 THL1_RS22795 7a173dd768a1f15324d97091931c5707 257 Hamap MF_01523 Ribosomal RNA small subunit methyltransferase J [rsmJ]. 5 253 39.548 T 13-09-2016 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 THL1_RS22795 7a173dd768a1f15324d97091931c5707 257 PANTHER PTHR36112:SF1 2 257 7.3E-121 T 13-09-2016 THL1_RS22795 7a173dd768a1f15324d97091931c5707 257 SUPERFAMILY SSF53335 14 254 4.48E-74 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS22795 7a173dd768a1f15324d97091931c5707 257 PANTHER PTHR36112 2 257 7.3E-121 T 13-09-2016 THL1_RS22795 7a173dd768a1f15324d97091931c5707 257 Pfam PF04445 Putative SAM-dependent methyltransferase 25 251 2.4E-93 T 13-09-2016 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 THL1_RS22795 7a173dd768a1f15324d97091931c5707 257 Gene3D G3DSA:3.40.50.150 62 254 2.3E-77 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS19765 e0dcce88f7ff9f71f786dcd2c065c3f5 396 PANTHER PTHR11751:SF301 16 386 2.3E-127 T 13-09-2016 THL1_RS19765 e0dcce88f7ff9f71f786dcd2c065c3f5 396 Gene3D G3DSA:3.90.1150.10 256 386 3.9E-35 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS19765 e0dcce88f7ff9f71f786dcd2c065c3f5 396 Pfam PF00155 Aminotransferase class I and II 33 382 2.7E-67 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS19765 e0dcce88f7ff9f71f786dcd2c065c3f5 396 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 13-09-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 THL1_RS19765 e0dcce88f7ff9f71f786dcd2c065c3f5 396 PANTHER PTHR11751 16 386 2.3E-127 T 13-09-2016 THL1_RS19765 e0dcce88f7ff9f71f786dcd2c065c3f5 396 Gene3D G3DSA:3.40.640.10 46 255 4.5E-70 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS19765 e0dcce88f7ff9f71f786dcd2c065c3f5 396 SUPERFAMILY SSF53383 16 387 1.1E-111 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS21430 dabb19b4ae1535bee0a8f81fddb871bb 272 SUPERFAMILY SSF52096 18 271 2.96E-79 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS21430 dabb19b4ae1535bee0a8f81fddb871bb 272 PANTHER PTHR11941 4 269 1.6E-194 T 13-09-2016 THL1_RS21430 dabb19b4ae1535bee0a8f81fddb871bb 272 Gene3D G3DSA:1.10.12.10 215 272 6.6E-15 T 13-09-2016 IPR014748 Crontonase, C-terminal THL1_RS21430 dabb19b4ae1535bee0a8f81fddb871bb 272 Gene3D G3DSA:3.90.226.10 18 213 5.2E-65 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS21430 dabb19b4ae1535bee0a8f81fddb871bb 272 PANTHER PTHR11941:SF89 4 269 1.6E-194 T 13-09-2016 THL1_RS21430 dabb19b4ae1535bee0a8f81fddb871bb 272 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 113 133 - T 13-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THL1_RS21430 dabb19b4ae1535bee0a8f81fddb871bb 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 27 271 1.8E-53 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS11160 5759aeb1fbb7e38993d2436d09e7925d 161 SUPERFAMILY SSF51182 41 159 6.52E-31 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS11160 5759aeb1fbb7e38993d2436d09e7925d 161 Pfam PF07883 Cupin domain 70 133 7.4E-12 T 13-09-2016 IPR013096 Cupin 2, conserved barrel THL1_RS11160 5759aeb1fbb7e38993d2436d09e7925d 161 PANTHER PTHR33570 24 159 2.7E-47 T 13-09-2016 THL1_RS11160 5759aeb1fbb7e38993d2436d09e7925d 161 Gene3D G3DSA:2.60.120.10 30 158 1.5E-34 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS11160 5759aeb1fbb7e38993d2436d09e7925d 161 PANTHER PTHR33570:SF5 24 159 2.7E-47 T 13-09-2016 THL1_RS19400 7d432c2fe183e409f7f1987f42d446ab 403 SUPERFAMILY SSF48452 146 254 8.39E-16 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS19400 7d432c2fe183e409f7f1987f42d446ab 403 PANTHER PTHR12558:SF12 141 357 2.4E-34 T 13-09-2016 THL1_RS19400 7d432c2fe183e409f7f1987f42d446ab 403 Gene3D G3DSA:1.25.40.10 189 271 4.9E-30 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS19400 7d432c2fe183e409f7f1987f42d446ab 403 Pfam PF13432 Tetratricopeptide repeat 156 220 7.6E-7 T 13-09-2016 THL1_RS19400 7d432c2fe183e409f7f1987f42d446ab 403 PANTHER PTHR12558 141 357 2.4E-34 T 13-09-2016 THL1_RS19400 7d432c2fe183e409f7f1987f42d446ab 403 Gene3D G3DSA:1.25.40.10 119 188 1.6E-8 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS19400 7d432c2fe183e409f7f1987f42d446ab 403 SMART SM00028 221 254 22.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS19400 7d432c2fe183e409f7f1987f42d446ab 403 SMART SM00028 150 183 0.1 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS19400 7d432c2fe183e409f7f1987f42d446ab 403 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 4 116 5.9E-30 T 13-09-2016 IPR017560 Cytochrome c-type biogenesis protein CcmI THL1_RS09395 6059d1278a1e71e83159083d25808d45 692 SUPERFAMILY SSF48452 651 676 1.55E-5 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS09395 6059d1278a1e71e83159083d25808d45 692 SUPERFAMILY SSF48452 438 470 1.55E-5 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS09395 6059d1278a1e71e83159083d25808d45 692 SMART SM00257 151 207 0.0092 T 13-09-2016 IPR018392 LysM domain THL1_RS09395 6059d1278a1e71e83159083d25808d45 692 Pfam PF01476 LysM domain 152 207 3.8E-4 T 13-09-2016 IPR018392 LysM domain THL1_RS09395 6059d1278a1e71e83159083d25808d45 692 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 158 216 9.1E-15 T 13-09-2016 IPR020012 Motility protein FimV, N-terminal THL1_RS09395 6059d1278a1e71e83159083d25808d45 692 Gene3D G3DSA:1.25.40.10 648 678 1.7E-7 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS09395 6059d1278a1e71e83159083d25808d45 692 Gene3D G3DSA:1.25.40.10 438 512 1.7E-7 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS09395 6059d1278a1e71e83159083d25808d45 692 Gene3D G3DSA:3.10.350.10 151 207 1.5E-5 T 13-09-2016 IPR018392 LysM domain THL1_RS09395 6059d1278a1e71e83159083d25808d45 692 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 648 691 8.6E-16 T 13-09-2016 IPR020011 Motility protein FimV, C-terminal THL1_RS18870 8fc41bb18038cd9ab5e9b395fa227159 243 PANTHER PTHR42208:SF1 1 225 3.1E-69 T 13-09-2016 THL1_RS18870 8fc41bb18038cd9ab5e9b395fa227159 243 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 10 213 3.0E-56 T 13-09-2016 THL1_RS18870 8fc41bb18038cd9ab5e9b395fa227159 243 SUPERFAMILY SSF103473 7 225 8.37E-6 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS18870 8fc41bb18038cd9ab5e9b395fa227159 243 PANTHER PTHR42208 1 225 3.1E-69 T 13-09-2016 THL1_RS22675 b4462c561d8b0affab8ea5bd9d463b40 135 PANTHER PTHR12735 1 133 1.0E-48 T 13-09-2016 THL1_RS22675 b4462c561d8b0affab8ea5bd9d463b40 135 PANTHER PTHR12735:SF26 1 133 1.0E-48 T 13-09-2016 THL1_RS22675 b4462c561d8b0affab8ea5bd9d463b40 135 Gene3D G3DSA:3.90.1010.10 1 134 1.9E-46 T 13-09-2016 THL1_RS22675 b4462c561d8b0affab8ea5bd9d463b40 135 SUPERFAMILY SSF82649 2 133 2.3E-42 T 13-09-2016 THL1_RS22675 b4462c561d8b0affab8ea5bd9d463b40 135 Pfam PF02657 Fe-S metabolism associated domain 12 131 8.8E-40 T 13-09-2016 IPR003808 Fe-S metabolism associated domain, SufE-like UniPathway: UPA00266 THL1_RS02215 3cfcf5f9279b971c39a4d06c8a38d7fc 264 Pfam PF00795 Carbon-nitrogen hydrolase 2 246 7.2E-54 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS02215 3cfcf5f9279b971c39a4d06c8a38d7fc 264 Gene3D G3DSA:3.60.110.10 1 262 3.7E-75 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS02215 3cfcf5f9279b971c39a4d06c8a38d7fc 264 SUPERFAMILY SSF56317 1 262 1.57E-73 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS02215 3cfcf5f9279b971c39a4d06c8a38d7fc 264 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 142 162 - T 13-09-2016 IPR001110 Uncharacterised protein family UPF0012, conserved site THL1_RS02215 3cfcf5f9279b971c39a4d06c8a38d7fc 264 PANTHER PTHR23088 1 263 2.2E-70 T 13-09-2016 THL1_RS02215 3cfcf5f9279b971c39a4d06c8a38d7fc 264 PANTHER PTHR23088:SF27 1 263 2.2E-70 T 13-09-2016 THL1_RS15305 456a4f9926b8968e373ec9b7e31747df 448 PANTHER PTHR24421 105 447 3.4E-49 T 13-09-2016 THL1_RS15305 456a4f9926b8968e373ec9b7e31747df 448 PIRSF PIRSF037314 1 448 1.0E-173 T 13-09-2016 IPR017171 Signal transduction histidine kinase, MctS THL1_RS15305 456a4f9926b8968e373ec9b7e31747df 448 Pfam PF17200 Single Cache domain 2 46 190 6.3E-39 T 13-09-2016 IPR033480 Single Cache domain 2 THL1_RS15305 456a4f9926b8968e373ec9b7e31747df 448 Gene3D G3DSA:3.30.450.20 37 184 8.4E-47 T 13-09-2016 THL1_RS15305 456a4f9926b8968e373ec9b7e31747df 448 SUPERFAMILY SSF55874 324 444 9.3E-16 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS15305 456a4f9926b8968e373ec9b7e31747df 448 SMART SM01049 42 132 1.7E-30 T 13-09-2016 IPR033480 Single Cache domain 2 THL1_RS15305 456a4f9926b8968e373ec9b7e31747df 448 Gene3D G3DSA:3.30.565.10 338 446 5.6E-10 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS15305 456a4f9926b8968e373ec9b7e31747df 448 SMART SM00387 354 447 3.1E-9 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS15305 456a4f9926b8968e373ec9b7e31747df 448 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 445 1.3E-5 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS15305 456a4f9926b8968e373ec9b7e31747df 448 PANTHER PTHR24421:SF1 105 447 3.4E-49 T 13-09-2016 THL1_RS15305 456a4f9926b8968e373ec9b7e31747df 448 Pfam PF07730 Histidine kinase 249 316 6.3E-17 T 13-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 THL1_RS27945 5863459979931832eab87b3dfb3206f0 468 PANTHER PTHR33525 83 468 5.3E-101 T 13-09-2016 THL1_RS27945 5863459979931832eab87b3dfb3206f0 468 Pfam PF04073 Aminoacyl-tRNA editing domain 35 142 2.1E-15 T 13-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THL1_RS27945 5863459979931832eab87b3dfb3206f0 468 SUPERFAMILY SSF55826 18 145 1.44E-15 T 13-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THL1_RS27945 5863459979931832eab87b3dfb3206f0 468 PIRSF PIRSF036888 1 466 1.3E-263 T 13-09-2016 IPR014627 Uncharacterised conserved protein UCP036888, signal transduction HD-GYP-like, PA5346 type THL1_RS27945 5863459979931832eab87b3dfb3206f0 468 Pfam PF08668 HDOD domain 195 395 2.0E-46 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS27945 5863459979931832eab87b3dfb3206f0 468 SUPERFAMILY SSF109604 180 452 4.08E-60 T 13-09-2016 THL1_RS27945 5863459979931832eab87b3dfb3206f0 468 PANTHER PTHR33525:SF3 83 468 5.3E-101 T 13-09-2016 THL1_RS27945 5863459979931832eab87b3dfb3206f0 468 Gene3D G3DSA:1.10.3150.10 177 452 1.7E-75 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS27945 5863459979931832eab87b3dfb3206f0 468 Gene3D G3DSA:3.90.960.10 37 147 8.2E-9 T 13-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THL1_RS23035 4e7ec04f93296e661eaa73e753a1517e 399 PANTHER PTHR24023 75 386 1.4E-29 T 13-09-2016 THL1_RS23035 4e7ec04f93296e661eaa73e753a1517e 399 Pfam PF02515 CoA-transferase family III 8 376 1.1E-117 T 13-09-2016 IPR003673 CoA-transferase family III GO:0003824 THL1_RS23035 4e7ec04f93296e661eaa73e753a1517e 399 Gene3D G3DSA:3.30.1540.10 226 308 6.9E-22 T 13-09-2016 THL1_RS23035 4e7ec04f93296e661eaa73e753a1517e 399 SUPERFAMILY SSF89796 6 399 1.96E-132 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS23035 4e7ec04f93296e661eaa73e753a1517e 399 Gene3D G3DSA:3.40.50.10540 4 219 1.2E-107 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS23035 4e7ec04f93296e661eaa73e753a1517e 399 Gene3D G3DSA:3.40.50.10540 309 399 1.2E-107 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS23035 4e7ec04f93296e661eaa73e753a1517e 399 PANTHER PTHR24023:SF593 75 386 1.4E-29 T 13-09-2016 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 Gene3D G3DSA:3.40.190.10 380 477 4.5E-13 T 13-09-2016 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 SUPERFAMILY SSF53850 51 274 5.43E-30 T 13-09-2016 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 PANTHER PTHR24423:SF382 1 8 1.5E-165 T 13-09-2016 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 Pfam PF08448 PAS fold 584 694 5.1E-9 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 SMART SM00091 577 645 7.8E-4 T 13-09-2016 IPR000014 PAS domain THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 Gene3D G3DSA:3.40.50.2300 958 1081 1.8E-36 T 13-09-2016 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 Gene3D G3DSA:3.40.190.10 301 379 4.4E-23 T 13-09-2016 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 Gene3D G3DSA:3.40.190.10 483 523 4.4E-23 T 13-09-2016 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 Pfam PF00512 His Kinase A (phospho-acceptor) domain 712 775 1.2E-17 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 SMART SM00387 822 938 3.3E-36 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 Pfam PF00072 Response regulator receiver domain 961 1075 4.0E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 Gene3D G3DSA:3.40.190.10 54 184 4.2E-11 T 13-09-2016 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 825 936 6.5E-28 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 SUPERFAMILY SSF53850 305 523 1.89E-43 T 13-09-2016 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 PANTHER PTHR24423 555 1117 1.5E-165 T 13-09-2016 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 PANTHER PTHR24423 1 8 1.5E-165 T 13-09-2016 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 SUPERFAMILY SSF47226 1058 1176 3.24E-11 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 SMART SM00448 959 1075 3.8E-33 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 PANTHER PTHR24423:SF382 555 1117 1.5E-165 T 13-09-2016 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 SMART SM00062 57 278 1.4E-28 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 SMART SM00062 302 523 2.8E-37 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 SUPERFAMILY SSF52172 959 1080 1.05E-34 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 SUPERFAMILY SSF55874 765 936 3.41E-42 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 SUPERFAMILY SSF55785 563 690 2.44E-15 T 13-09-2016 IPR000014 PAS domain THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 PRINTS PR00344 Bacterial sensor protein C-terminal signature 898 916 1.7E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 PRINTS PR00344 Bacterial sensor protein C-terminal signature 863 877 1.7E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 PRINTS PR00344 Bacterial sensor protein C-terminal signature 881 891 1.7E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 PRINTS PR00344 Bacterial sensor protein C-terminal signature 922 935 1.7E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 305 521 9.1E-35 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 58 276 3.1E-19 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 Gene3D G3DSA:3.30.450.20 567 692 5.5E-14 T 13-09-2016 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 Gene3D G3DSA:1.10.287.130 704 771 2.4E-15 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 SUPERFAMILY SSF47384 695 776 8.44E-20 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 SMART SM00388 712 775 1.7E-21 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 Gene3D G3DSA:3.30.565.10 776 940 1.9E-43 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS10385 4f1a2c5e12a4adaa3b10904cee8d710c 1206 Gene3D G3DSA:1.20.120.160 1096 1189 7.7E-6 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS22565 e10da13270e24979f4aa1b1024d6231a 1174 PANTHER PTHR32294 1 895 0.0 T 13-09-2016 THL1_RS22565 e10da13270e24979f4aa1b1024d6231a 1174 PANTHER PTHR32294 911 1174 0.0 T 13-09-2016 THL1_RS22565 e10da13270e24979f4aa1b1024d6231a 1174 SMART SM00481 6 73 8.0E-26 T 13-09-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 THL1_RS22565 e10da13270e24979f4aa1b1024d6231a 1174 Gene3D G3DSA:2.40.50.140 996 1091 9.5E-10 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS22565 e10da13270e24979f4aa1b1024d6231a 1174 PANTHER PTHR32294:SF0 1 895 0.0 T 13-09-2016 THL1_RS22565 e10da13270e24979f4aa1b1024d6231a 1174 PANTHER PTHR32294:SF0 911 1174 0.0 T 13-09-2016 THL1_RS22565 e10da13270e24979f4aa1b1024d6231a 1174 Pfam PF14579 Helix-hairpin-helix motif 811 894 5.1E-26 T 13-09-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS22565 e10da13270e24979f4aa1b1024d6231a 1174 Pfam PF01336 OB-fold nucleic acid binding domain 1011 1083 1.3E-8 T 13-09-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 THL1_RS22565 e10da13270e24979f4aa1b1024d6231a 1174 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 290 737 2.2E-177 T 13-09-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS22565 e10da13270e24979f4aa1b1024d6231a 1174 SUPERFAMILY SSF89550 5 262 1.0E-13 T 13-09-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 THL1_RS22565 e10da13270e24979f4aa1b1024d6231a 1174 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1046 0.0 T 13-09-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS22565 e10da13270e24979f4aa1b1024d6231a 1174 Pfam PF02811 PHP domain 7 171 2.0E-41 T 13-09-2016 IPR004013 PHP domain GO:0003824 THL1_RS22565 e10da13270e24979f4aa1b1024d6231a 1174 Gene3D G3DSA:3.20.20.140 5 256 4.8E-22 T 13-09-2016 THL1_RS22565 e10da13270e24979f4aa1b1024d6231a 1174 Gene3D G3DSA:1.10.150.280 837 884 1.7E-6 T 13-09-2016 THL1_RS11840 599fe640e80e27fa75eed0b9b11178c4 244 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 40 235 6.5E-85 T 13-09-2016 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8|UniPathway: UPA00140 THL1_RS11840 599fe640e80e27fa75eed0b9b11178c4 244 PANTHER PTHR23293 6 240 3.6E-108 T 13-09-2016 THL1_RS11840 599fe640e80e27fa75eed0b9b11178c4 244 Gene3D G3DSA:3.40.50.620 3 207 5.3E-53 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS11840 599fe640e80e27fa75eed0b9b11178c4 244 PIRSF PIRSF000857 2 241 6.9E-82 T 13-09-2016 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8|UniPathway: UPA00140 THL1_RS11840 599fe640e80e27fa75eed0b9b11178c4 244 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 34 211 2.2E-47 T 13-09-2016 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 THL1_RS11840 599fe640e80e27fa75eed0b9b11178c4 244 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 2 237 35.458 T 13-09-2016 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8|UniPathway: UPA00140 THL1_RS11840 599fe640e80e27fa75eed0b9b11178c4 244 PANTHER PTHR23293:SF11 6 240 3.6E-108 T 13-09-2016 THL1_RS11840 599fe640e80e27fa75eed0b9b11178c4 244 SUPERFAMILY SSF52402 8 199 4.95E-47 T 13-09-2016 THL1_RS11840 599fe640e80e27fa75eed0b9b11178c4 244 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 19 236 4.7E-51 T 13-09-2016 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8|UniPathway: UPA00140 THL1_RS08105 d0dc9ebcdddf021437876c925b8a7b70 364 SUPERFAMILY SSF117916 5 81 4.58E-14 T 13-09-2016 THL1_RS08105 d0dc9ebcdddf021437876c925b8a7b70 364 PANTHER PTHR23264:SF19 1 354 5.5E-158 T 13-09-2016 THL1_RS08105 d0dc9ebcdddf021437876c925b8a7b70 364 PANTHER PTHR23264 1 354 5.5E-158 T 13-09-2016 IPR019591 Mrp/NBP35 ATP-binding protein THL1_RS08105 d0dc9ebcdddf021437876c925b8a7b70 364 SUPERFAMILY SSF52540 91 327 1.95E-58 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08105 d0dc9ebcdddf021437876c925b8a7b70 364 Hamap MF_02040 Iron-sulfur cluster carrier protein. 93 343 36.902 T 13-09-2016 IPR019591 Mrp/NBP35 ATP-binding protein THL1_RS08105 d0dc9ebcdddf021437876c925b8a7b70 364 Gene3D G3DSA:3.40.50.300 89 341 1.5E-103 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08105 d0dc9ebcdddf021437876c925b8a7b70 364 ProSitePatterns PS01215 Mrp family signature. 206 222 - T 13-09-2016 IPR000808 Mrp, conserved site GO:0005524 THL1_RS08105 d0dc9ebcdddf021437876c925b8a7b70 364 Pfam PF01883 Domain of unknown function DUF59 6 79 2.6E-17 T 13-09-2016 IPR002744 Domain of unknown function DUF59 THL1_RS08105 d0dc9ebcdddf021437876c925b8a7b70 364 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 97 342 2.3E-100 T 13-09-2016 IPR019591 Mrp/NBP35 ATP-binding protein THL1_RS11995 7b197f3e4e6c6d8d93e29d5c2b6b40c9 475 SUPERFAMILY SSF82689 223 307 3.79E-5 T 13-09-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 THL1_RS11995 7b197f3e4e6c6d8d93e29d5c2b6b40c9 475 Pfam PF00924 Mechanosensitive ion channel 109 306 5.2E-35 T 13-09-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 THL1_RS11995 7b197f3e4e6c6d8d93e29d5c2b6b40c9 475 SUPERFAMILY SSF50182 151 216 3.92E-15 T 13-09-2016 IPR010920 LSM domain THL1_RS11995 7b197f3e4e6c6d8d93e29d5c2b6b40c9 475 SMART SM00100 328 445 1.8E-10 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS11995 7b197f3e4e6c6d8d93e29d5c2b6b40c9 475 PANTHER PTHR30221 14 349 4.4E-26 T 13-09-2016 THL1_RS11995 7b197f3e4e6c6d8d93e29d5c2b6b40c9 475 Gene3D G3DSA:2.30.30.60 166 215 1.2E-15 T 13-09-2016 THL1_RS11995 7b197f3e4e6c6d8d93e29d5c2b6b40c9 475 Pfam PF00027 Cyclic nucleotide-binding domain 348 431 4.8E-12 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS11995 7b197f3e4e6c6d8d93e29d5c2b6b40c9 475 Gene3D G3DSA:2.60.120.10 322 442 4.8E-18 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS11995 7b197f3e4e6c6d8d93e29d5c2b6b40c9 475 PIRSF PIRSF026673 1 474 1.3E-172 T 13-09-2016 IPR016846 Predicted ion channel, cNMP-binding THL1_RS11995 7b197f3e4e6c6d8d93e29d5c2b6b40c9 475 SUPERFAMILY SSF51206 321 443 1.57E-19 T 13-09-2016 IPR018490 Cyclic nucleotide-binding-like THL1_RS24435 763540b9d03f3757d7aee77a967062e2 283 PANTHER PTHR20941:SF1 5 283 8.9E-112 T 13-09-2016 THL1_RS24435 763540b9d03f3757d7aee77a967062e2 283 SUPERFAMILY SSF51717 11 280 1.1E-102 T 13-09-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 THL1_RS24435 763540b9d03f3757d7aee77a967062e2 283 Pfam PF00809 Pterin binding enzyme 25 264 4.7E-81 T 13-09-2016 IPR000489 Pterin-binding domain GO:0042558 THL1_RS24435 763540b9d03f3757d7aee77a967062e2 283 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 24 39 - T 13-09-2016 IPR000489 Pterin-binding domain GO:0042558 THL1_RS24435 763540b9d03f3757d7aee77a967062e2 283 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 58 71 - T 13-09-2016 IPR000489 Pterin-binding domain GO:0042558 THL1_RS24435 763540b9d03f3757d7aee77a967062e2 283 Gene3D G3DSA:3.20.20.20 19 281 5.0E-105 T 13-09-2016 IPR000489 Pterin-binding domain GO:0042558 THL1_RS24435 763540b9d03f3757d7aee77a967062e2 283 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 23 278 3.2E-98 T 13-09-2016 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614|UniPathway: UPA00077 THL1_RS24435 763540b9d03f3757d7aee77a967062e2 283 PANTHER PTHR20941 5 283 8.9E-112 T 13-09-2016 THL1_RS14715 3c1c6251322a75830719c317fbf2c346 251 PANTHER PTHR10672 1 222 2.7E-103 T 13-09-2016 THL1_RS14715 3c1c6251322a75830719c317fbf2c346 251 SUPERFAMILY SSF53639 8 224 7.06E-60 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS14715 3c1c6251322a75830719c317fbf2c346 251 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 16 198 1.1E-44 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS14715 3c1c6251322a75830719c317fbf2c346 251 Gene3D G3DSA:3.40.225.10 11 226 2.2E-62 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS14715 3c1c6251322a75830719c317fbf2c346 251 SMART SM01007 16 198 3.3E-58 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS02780 3e88a373079fb627c4bd15c86cb7f459 318 PANTHER PTHR11019:SF50 75 314 5.0E-30 T 13-09-2016 THL1_RS02780 3e88a373079fb627c4bd15c86cb7f459 318 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 265 309 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS02780 3e88a373079fb627c4bd15c86cb7f459 318 Pfam PF12833 Helix-turn-helix domain 235 314 3.8E-19 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS02780 3e88a373079fb627c4bd15c86cb7f459 318 SUPERFAMILY SSF46689 265 314 1.66E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS02780 3e88a373079fb627c4bd15c86cb7f459 318 PANTHER PTHR11019 75 314 5.0E-30 T 13-09-2016 THL1_RS02780 3e88a373079fb627c4bd15c86cb7f459 318 Pfam PF14525 AraC-binding-like domain 19 192 6.5E-22 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS02780 3e88a373079fb627c4bd15c86cb7f459 318 Gene3D G3DSA:1.10.10.60 214 264 1.6E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS02780 3e88a373079fb627c4bd15c86cb7f459 318 SMART SM00342 229 313 1.3E-25 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS02780 3e88a373079fb627c4bd15c86cb7f459 318 Gene3D G3DSA:1.10.10.60 265 315 9.3E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS06185 a96883950b9781d6c8f21dde8a1098af 217 PANTHER PTHR34315 32 217 8.6E-44 T 13-09-2016 THL1_RS06185 a96883950b9781d6c8f21dde8a1098af 217 Pfam PF00775 Dioxygenase 42 134 1.2E-11 T 13-09-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 THL1_RS06185 a96883950b9781d6c8f21dde8a1098af 217 PANTHER PTHR34315:SF1 32 217 8.6E-44 T 13-09-2016 THL1_RS06185 a96883950b9781d6c8f21dde8a1098af 217 SUPERFAMILY SSF49482 26 190 9.94E-46 T 13-09-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 THL1_RS06185 a96883950b9781d6c8f21dde8a1098af 217 Gene3D G3DSA:2.60.130.10 28 191 1.5E-44 T 13-09-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 Gene3D G3DSA:3.50.50.60 150 269 7.7E-37 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 Gene3D G3DSA:3.30.390.30 341 464 5.1E-49 T 13-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 PIRSF PIRSF000350 1 464 2.5E-89 T 13-09-2016 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 PANTHER PTHR22912:SF151 4 462 2.5E-251 T 13-09-2016 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 350 458 7.9E-40 T 13-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 Gene3D G3DSA:3.50.50.60 3 148 8.9E-43 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 Gene3D G3DSA:3.50.50.60 270 340 1.8E-20 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 SUPERFAMILY SSF55424 347 466 2.23E-42 T 13-09-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 331 1.3E-71 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 2.3E-36 T 13-09-2016 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 296 318 2.3E-36 T 13-09-2016 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 2.3E-36 T 13-09-2016 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 284 2.3E-36 T 13-09-2016 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.3E-36 T 13-09-2016 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 SUPERFAMILY SSF51905 3 371 8.96E-60 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 13-09-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 467 1.7E-162 T 13-09-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 411 426 1.8E-79 T 13-09-2016 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 140 149 1.8E-79 T 13-09-2016 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.8E-79 T 13-09-2016 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 433 453 1.8E-79 T 13-09-2016 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 346 367 1.8E-79 T 13-09-2016 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 1.8E-79 T 13-09-2016 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 1.8E-79 T 13-09-2016 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 311 318 1.8E-79 T 13-09-2016 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 283 1.8E-79 T 13-09-2016 THL1_RS12150 960067ff3855bd2e2da33f769b095e67 469 PANTHER PTHR22912 4 462 2.5E-251 T 13-09-2016 THL1_RS09285 d87bf01c0782caabfe372f4d0d9ca374 243 Pfam PF00005 ABC transporter 20 167 2.7E-38 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS09285 d87bf01c0782caabfe372f4d0d9ca374 243 SUPERFAMILY SSF52540 4 237 3.9E-82 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09285 d87bf01c0782caabfe372f4d0d9ca374 243 PANTHER PTHR24220:SF474 6 241 2.9E-154 T 13-09-2016 THL1_RS09285 d87bf01c0782caabfe372f4d0d9ca374 243 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS09285 d87bf01c0782caabfe372f4d0d9ca374 243 PANTHER PTHR24220 6 241 2.9E-154 T 13-09-2016 THL1_RS09285 d87bf01c0782caabfe372f4d0d9ca374 243 Gene3D G3DSA:3.40.50.300 3 239 1.4E-87 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09285 d87bf01c0782caabfe372f4d0d9ca374 243 SMART SM00382 29 215 1.8E-15 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS09285 d87bf01c0782caabfe372f4d0d9ca374 243 PIRSF PIRSF039085 1 243 4.2E-107 T 13-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 THL1_RS01065 f349cd81152b621cb9472083c494e7ad 459 PANTHER PTHR11119 11 453 5.5E-237 T 13-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS01065 f349cd81152b621cb9472083c494e7ad 459 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 27 448 1.1E-118 T 13-09-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 THL1_RS01065 f349cd81152b621cb9472083c494e7ad 459 Pfam PF00860 Permease family 29 420 8.4E-92 T 13-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS01065 f349cd81152b621cb9472083c494e7ad 459 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 368 388 - T 13-09-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 THL1_RS01065 f349cd81152b621cb9472083c494e7ad 459 TIGRFAM TIGR03173 pbuX: xanthine permease 33 452 2.7E-125 T 13-09-2016 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 THL1_RS01065 f349cd81152b621cb9472083c494e7ad 459 PANTHER PTHR11119:SF44 11 453 5.5E-237 T 13-09-2016 THL1_RS16390 c31a735d1e5900f40a92775fdd3d3622 277 Gene3D G3DSA:3.30.1130.10 16 132 1.1E-38 T 13-09-2016 THL1_RS16390 c31a735d1e5900f40a92775fdd3d3622 277 SUPERFAMILY SSF55620 180 264 3.48E-11 T 13-09-2016 THL1_RS16390 c31a735d1e5900f40a92775fdd3d3622 277 Gene3D G3DSA:3.30.1130.10 141 277 2.5E-48 T 13-09-2016 THL1_RS16390 c31a735d1e5900f40a92775fdd3d3622 277 Pfam PF14489 QueF-like protein 190 266 2.5E-24 T 13-09-2016 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS16390 c31a735d1e5900f40a92775fdd3d3622 277 PIRSF PIRSF004750 1 277 7.0E-115 T 13-09-2016 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS16390 c31a735d1e5900f40a92775fdd3d3622 277 PANTHER PTHR34354 1 277 1.7E-89 T 13-09-2016 THL1_RS16390 c31a735d1e5900f40a92775fdd3d3622 277 PANTHER PTHR34354:SF1 1 277 1.7E-89 T 13-09-2016 THL1_RS16390 c31a735d1e5900f40a92775fdd3d3622 277 TIGRFAM TIGR03138 QueF: queuine synthase 5 277 1.5E-116 T 13-09-2016 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS16390 c31a735d1e5900f40a92775fdd3d3622 277 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 277 144.707 T 13-09-2016 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS16390 c31a735d1e5900f40a92775fdd3d3622 277 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 16 125 7.5E-46 T 13-09-2016 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS11915 ba30e479e4c2a87fb1df1031a03aa6b6 101 SUPERFAMILY SSF58104 2 100 2.88E-15 T 13-09-2016 THL1_RS11915 ba30e479e4c2a87fb1df1031a03aa6b6 101 PANTHER PTHR32089:SF34 1 101 7.7E-35 T 13-09-2016 THL1_RS11915 ba30e479e4c2a87fb1df1031a03aa6b6 101 PANTHER PTHR32089 1 101 7.7E-35 T 13-09-2016 THL1_RS11915 ba30e479e4c2a87fb1df1031a03aa6b6 101 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 3 99 2.3E-11 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS11915 ba30e479e4c2a87fb1df1031a03aa6b6 101 Gene3D G3DSA:1.10.287.950 2 70 1.5E-8 T 13-09-2016 THL1_RS02090 0ff7ccea529944857735fddd00c60da4 476 Gene3D G3DSA:1.10.287.130 258 315 8.2E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS02090 0ff7ccea529944857735fddd00c60da4 476 SMART SM00304 204 255 1.1E-4 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS02090 0ff7ccea529944857735fddd00c60da4 476 SMART SM00388 255 320 5.7E-16 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS02090 0ff7ccea529944857735fddd00c60da4 476 SUPERFAMILY SSF103190 85 177 8.24E-12 T 13-09-2016 IPR029151 Periplasmic sensor domain-like THL1_RS02090 0ff7ccea529944857735fddd00c60da4 476 PANTHER PTHR24423 95 133 3.0E-58 T 13-09-2016 THL1_RS02090 0ff7ccea529944857735fddd00c60da4 476 PANTHER PTHR24423 198 473 3.0E-58 T 13-09-2016 THL1_RS02090 0ff7ccea529944857735fddd00c60da4 476 SUPERFAMILY SSF55874 310 473 4.45E-29 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS02090 0ff7ccea529944857735fddd00c60da4 476 Pfam PF00672 HAMP domain 185 251 7.2E-11 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS02090 0ff7ccea529944857735fddd00c60da4 476 SUPERFAMILY SSF47384 241 319 1.79E-13 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS02090 0ff7ccea529944857735fddd00c60da4 476 SMART SM00387 365 475 1.8E-17 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS02090 0ff7ccea529944857735fddd00c60da4 476 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 370 472 2.7E-10 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS02090 0ff7ccea529944857735fddd00c60da4 476 Gene3D G3DSA:3.30.565.10 327 473 2.8E-26 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS02090 0ff7ccea529944857735fddd00c60da4 476 Pfam PF00512 His Kinase A (phospho-acceptor) domain 258 319 2.5E-13 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 PANTHER PTHR11615:SF19 81 300 2.8E-45 T 13-09-2016 THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 PANTHER PTHR11615:SF19 326 587 2.8E-45 T 13-09-2016 THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 Gene3D G3DSA:3.40.50.740 206 299 7.1E-48 T 13-09-2016 THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 Gene3D G3DSA:3.40.50.740 797 808 7.1E-48 T 13-09-2016 THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 Gene3D G3DSA:3.40.50.740 508 754 7.1E-48 T 13-09-2016 THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 SUPERFAMILY SSF50692 843 983 3.84E-24 T 13-09-2016 IPR009010 Aspartate decarboxylase-like domain THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 PANTHER PTHR11615 765 994 2.8E-45 T 13-09-2016 THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 PANTHER PTHR11615 603 743 2.8E-45 T 13-09-2016 THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 PANTHER PTHR11615 81 300 2.8E-45 T 13-09-2016 THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 PANTHER PTHR11615 326 587 2.8E-45 T 13-09-2016 THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 SUPERFAMILY SSF53706 140 847 1.31E-140 T 13-09-2016 THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 Pfam PF00384 Molybdopterin oxidoreductase 206 713 7.0E-36 T 13-09-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 Gene3D G3DSA:3.40.228.10 316 507 9.7E-41 T 13-09-2016 THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 PANTHER PTHR11615:SF19 765 994 2.8E-45 T 13-09-2016 THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 PANTHER PTHR11615:SF19 603 743 2.8E-45 T 13-09-2016 THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 893 920 - T 13-09-2016 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 Pfam PF01568 Molydopterin dinucleotide binding domain 848 964 7.0E-13 T 13-09-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 THL1_RS13225 cd1e72578b940954a2557ba31d89fe17 999 Gene3D G3DSA:2.40.40.20 822 984 6.5E-35 T 13-09-2016 THL1_RS02960 1d256a7f30761bcb8394cca38372a7d2 172 Gene3D G3DSA:2.30.30.40 112 146 4.9E-4 T 13-09-2016 THL1_RS02960 1d256a7f30761bcb8394cca38372a7d2 172 Gene3D G3DSA:2.40.50.180 70 111 7.5E-7 T 13-09-2016 THL1_RS02960 1d256a7f30761bcb8394cca38372a7d2 172 Pfam PF01584 CheW-like domain 31 163 6.8E-31 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS02960 1d256a7f30761bcb8394cca38372a7d2 172 PANTHER PTHR22617 27 148 5.6E-26 T 13-09-2016 THL1_RS02960 1d256a7f30761bcb8394cca38372a7d2 172 SMART SM00260 27 161 1.7E-21 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS02960 1d256a7f30761bcb8394cca38372a7d2 172 SUPERFAMILY SSF50341 25 163 3.53E-30 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS26075 cda35b543ff9b939e15a674bbb625dac 474 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 331 471 9.3E-65 T 13-09-2016 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167|UniPathway: UPA00356|UniPathway: UPA00356 THL1_RS26075 cda35b543ff9b939e15a674bbb625dac 474 PANTHER PTHR10584:SF159 1 339 1.8E-144 T 13-09-2016 THL1_RS26075 cda35b543ff9b939e15a674bbb625dac 474 SUPERFAMILY SSF52374 339 470 6.57E-24 T 13-09-2016 THL1_RS26075 cda35b543ff9b939e15a674bbb625dac 474 Gene3D G3DSA:3.40.1190.20 12 313 6.1E-64 T 13-09-2016 IPR029056 Ribokinase-like THL1_RS26075 cda35b543ff9b939e15a674bbb625dac 474 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 5 311 3.9E-124 T 13-09-2016 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167|UniPathway: UPA00356|UniPathway: UPA00356 THL1_RS26075 cda35b543ff9b939e15a674bbb625dac 474 PANTHER PTHR10584 1 339 1.8E-144 T 13-09-2016 THL1_RS26075 cda35b543ff9b939e15a674bbb625dac 474 Pfam PF01467 Cytidylyltransferase-like 344 434 9.3E-16 T 13-09-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THL1_RS26075 cda35b543ff9b939e15a674bbb625dac 474 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 341 407 4.7E-16 T 13-09-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THL1_RS26075 cda35b543ff9b939e15a674bbb625dac 474 Gene3D G3DSA:3.40.50.620 339 457 4.7E-35 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS26075 cda35b543ff9b939e15a674bbb625dac 474 Hamap MF_01603 Bifunctional protein HldE [hldE]. 4 473 43.4 T 13-09-2016 IPR023030 Bifunctional protein HldE GO:0016773|GO:0016779 KEGG: 00040+2.7.1.16|KEGG: 00540+2.7.7.70+2.7.1.167|UniPathway: UPA00356|UniPathway: UPA00356 THL1_RS26075 cda35b543ff9b939e15a674bbb625dac 474 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 51 74 - T 13-09-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 THL1_RS26075 cda35b543ff9b939e15a674bbb625dac 474 SUPERFAMILY SSF53613 12 309 1.71E-58 T 13-09-2016 IPR029056 Ribokinase-like THL1_RS26075 cda35b543ff9b939e15a674bbb625dac 474 Pfam PF00294 pfkB family carbohydrate kinase 13 304 2.1E-47 T 13-09-2016 IPR011611 Carbohydrate kinase PfkB THL1_RS13985 3b681ea80271bc0af0347d40a154c0b6 322 Gene3D G3DSA:3.30.70.270 146 308 8.1E-49 T 13-09-2016 THL1_RS13985 3b681ea80271bc0af0347d40a154c0b6 322 PANTHER PTHR10799:SF750 26 310 2.0E-26 T 13-09-2016 THL1_RS13985 3b681ea80271bc0af0347d40a154c0b6 322 SUPERFAMILY SSF55785 15 129 8.68E-21 T 13-09-2016 IPR000014 PAS domain THL1_RS13985 3b681ea80271bc0af0347d40a154c0b6 322 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 7 133 1.6E-13 T 13-09-2016 IPR000014 PAS domain THL1_RS13985 3b681ea80271bc0af0347d40a154c0b6 322 SMART SM00267 133 309 2.5E-58 T 13-09-2016 IPR000160 GGDEF domain THL1_RS13985 3b681ea80271bc0af0347d40a154c0b6 322 Gene3D G3DSA:3.30.450.20 5 141 7.9E-25 T 13-09-2016 THL1_RS13985 3b681ea80271bc0af0347d40a154c0b6 322 PANTHER PTHR10799 26 310 2.0E-26 T 13-09-2016 THL1_RS13985 3b681ea80271bc0af0347d40a154c0b6 322 Pfam PF00990 Diguanylate cyclase, GGDEF domain 145 305 3.1E-49 T 13-09-2016 IPR000160 GGDEF domain THL1_RS13985 3b681ea80271bc0af0347d40a154c0b6 322 SUPERFAMILY SSF55073 149 306 1.49E-45 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS13985 3b681ea80271bc0af0347d40a154c0b6 322 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 140 308 4.4E-50 T 13-09-2016 IPR000160 GGDEF domain THL1_RS13985 3b681ea80271bc0af0347d40a154c0b6 322 Pfam PF08447 PAS fold 34 119 2.0E-13 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS13985 3b681ea80271bc0af0347d40a154c0b6 322 SMART SM00086 84 126 1.8E-6 T 13-09-2016 IPR001610 PAC motif THL1_RS13005 0a0bd24d981d2732f8e6d6a27f8c82f7 667 Pfam PF12392 Collagenase 400 512 8.0E-17 T 13-09-2016 IPR020988 Peptidase U32, collagenase KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS13005 0a0bd24d981d2732f8e6d6a27f8c82f7 667 PANTHER PTHR30217 1 659 8.8E-229 T 13-09-2016 THL1_RS13005 0a0bd24d981d2732f8e6d6a27f8c82f7 667 ProSitePatterns PS01276 Peptidase family U32 signature. 161 179 - T 13-09-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS13005 0a0bd24d981d2732f8e6d6a27f8c82f7 667 Pfam PF01136 Peptidase family U32 79 304 2.3E-69 T 13-09-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS13005 0a0bd24d981d2732f8e6d6a27f8c82f7 667 PANTHER PTHR30217:SF10 1 659 8.8E-229 T 13-09-2016 THL1_RS22355 a8914c3df198ccd5bd09a16e458127e9 884 PANTHER PTHR34697:SF2 26 874 4.8E-281 T 13-09-2016 THL1_RS22355 a8914c3df198ccd5bd09a16e458127e9 884 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 569 856 4.9E-90 T 13-09-2016 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal THL1_RS22355 a8914c3df198ccd5bd09a16e458127e9 884 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 44 331 3.1E-16 T 13-09-2016 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD THL1_RS22355 a8914c3df198ccd5bd09a16e458127e9 884 SUPERFAMILY SSF55729 679 854 1.96E-14 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS22355 a8914c3df198ccd5bd09a16e458127e9 884 PANTHER PTHR34697 26 874 4.8E-281 T 13-09-2016 THL1_RS14395 6b707c8f2128992e3a8941b1660c23c7 162 PANTHER PTHR41534 1 162 4.8E-87 T 13-09-2016 THL1_RS14395 6b707c8f2128992e3a8941b1660c23c7 162 TIGRFAM TIGR03232 benzo_1_2_benB: benzoate 1,2-dioxygenase, small subunit 8 162 1.3E-88 T 13-09-2016 IPR017641 Benzoate 1,2-dioxygenase, small subunit GO:0016708|GO:0055114 THL1_RS14395 6b707c8f2128992e3a8941b1660c23c7 162 Pfam PF00866 Ring hydroxylating beta subunit 14 154 3.3E-49 T 13-09-2016 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 THL1_RS14395 6b707c8f2128992e3a8941b1660c23c7 162 Gene3D G3DSA:3.10.450.50 5 155 6.7E-53 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS14395 6b707c8f2128992e3a8941b1660c23c7 162 SUPERFAMILY SSF54427 4 162 1.81E-55 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS14395 6b707c8f2128992e3a8941b1660c23c7 162 PANTHER PTHR41534:SF1 1 162 4.8E-87 T 13-09-2016 THL1_RS06840 10e6c07ca9ed95d266a5a9efc332aeab 101 Pfam PF01817 Chorismate mutase type II 13 89 1.5E-17 T 13-09-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 THL1_RS06840 10e6c07ca9ed95d266a5a9efc332aeab 101 Gene3D G3DSA:1.20.59.10 3 89 8.8E-17 T 13-09-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 THL1_RS06840 10e6c07ca9ed95d266a5a9efc332aeab 101 PANTHER PTHR38041 3 98 2.2E-16 T 13-09-2016 THL1_RS06840 10e6c07ca9ed95d266a5a9efc332aeab 101 SUPERFAMILY SSF48600 4 90 1.98E-23 T 13-09-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 THL1_RS06840 10e6c07ca9ed95d266a5a9efc332aeab 101 SMART SM00830 13 92 6.6E-23 T 13-09-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 THL1_RS09435 d72e6bfbee488782fbef2e693414068b 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 4.3E-17 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS09435 d72e6bfbee488782fbef2e693414068b 209 Pfam PF08362 YcdC-like protein, C-terminal region 59 200 2.7E-61 T 13-09-2016 IPR013573 Transcription regulator YcdC, C-terminal GO:0045892 THL1_RS09435 d72e6bfbee488782fbef2e693414068b 209 Gene3D G3DSA:1.10.357.10 63 200 1.6E-55 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS09435 d72e6bfbee488782fbef2e693414068b 209 PANTHER PTHR30055 1 163 1.6E-60 T 13-09-2016 THL1_RS09435 d72e6bfbee488782fbef2e693414068b 209 PANTHER PTHR30055:SF53 1 163 1.6E-60 T 13-09-2016 THL1_RS09435 d72e6bfbee488782fbef2e693414068b 209 Gene3D G3DSA:1.10.10.60 41 62 3.7E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS09435 d72e6bfbee488782fbef2e693414068b 209 SUPERFAMILY SSF48498 77 199 6.15E-43 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS09435 d72e6bfbee488782fbef2e693414068b 209 SUPERFAMILY SSF46689 4 73 3.39E-19 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS09435 d72e6bfbee488782fbef2e693414068b 209 Gene3D G3DSA:1.10.10.60 5 40 1.1E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS09435 d72e6bfbee488782fbef2e693414068b 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 4.2E-10 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS09435 d72e6bfbee488782fbef2e693414068b 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 4.2E-10 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS01260 e12a7eb917bee0a032626e5931b87e06 394 Pfam PF06969 HemN C-terminal domain 319 382 1.2E-12 T 13-09-2016 IPR010723 HemN, C-terminal THL1_RS01260 e12a7eb917bee0a032626e5931b87e06 394 PANTHER PTHR13932 20 394 2.9E-202 T 13-09-2016 THL1_RS01260 e12a7eb917bee0a032626e5931b87e06 394 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 23 383 5.0E-117 T 13-09-2016 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00071+1.3.99.-|KEGG: 00280+1.3.99.-|KEGG: 00281+1.3.99.-|KEGG: 00362+1.3.99.-|KEGG: 00626+1.3.99.-|KEGG: 00930+1.3.99.- THL1_RS01260 e12a7eb917bee0a032626e5931b87e06 394 Gene3D G3DSA:3.80.30.20 23 252 4.8E-34 T 13-09-2016 IPR023404 Radical SAM, alpha/beta horseshoe THL1_RS01260 e12a7eb917bee0a032626e5931b87e06 394 PANTHER PTHR13932:SF7 20 394 2.9E-202 T 13-09-2016 THL1_RS01260 e12a7eb917bee0a032626e5931b87e06 394 Pfam PF04055 Radical SAM superfamily 26 193 4.3E-19 T 13-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 THL1_RS01260 e12a7eb917bee0a032626e5931b87e06 394 SUPERFAMILY SSF102114 20 393 3.01E-109 T 13-09-2016 THL1_RS01260 e12a7eb917bee0a032626e5931b87e06 394 SMART SM00729 21 237 6.9E-57 T 13-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THL1_RS00505 86bced8e887d180441457b9a2040a975 497 PANTHER PTHR21432 1 494 1.1E-276 T 13-09-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 THL1_RS00505 86bced8e887d180441457b9a2040a975 497 SUPERFAMILY SSF100950 225 494 8.37E-87 T 13-09-2016 THL1_RS00505 86bced8e887d180441457b9a2040a975 497 SUPERFAMILY SSF100950 4 222 3.58E-76 T 13-09-2016 THL1_RS00505 86bced8e887d180441457b9a2040a975 497 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 14 215 2.2E-30 T 13-09-2016 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 THL1_RS00505 86bced8e887d180441457b9a2040a975 497 Gene3D G3DSA:3.40.1080.10 13 221 9.8E-44 T 13-09-2016 THL1_RS00505 86bced8e887d180441457b9a2040a975 497 PANTHER PTHR21432:SF10 1 494 1.1E-276 T 13-09-2016 THL1_RS00505 86bced8e887d180441457b9a2040a975 497 Gene3D G3DSA:3.40.810.20 225 490 4.7E-84 T 13-09-2016 THL1_RS00505 86bced8e887d180441457b9a2040a975 497 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 322 463 9.2E-42 T 13-09-2016 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain THL1_RS00505 86bced8e887d180441457b9a2040a975 497 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 14 494 1.3E-231 T 13-09-2016 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 THL1_RS03225 390f3000d015742c71ef3565dfe02452 310 PANTHER PTHR11019 23 294 1.4E-66 T 13-09-2016 THL1_RS03225 390f3000d015742c71ef3565dfe02452 310 Pfam PF12833 Helix-turn-helix domain 210 287 5.1E-19 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS03225 390f3000d015742c71ef3565dfe02452 310 Gene3D G3DSA:1.10.10.60 180 239 4.1E-7 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS03225 390f3000d015742c71ef3565dfe02452 310 SMART SM00342 203 286 3.3E-20 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS03225 390f3000d015742c71ef3565dfe02452 310 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 255 270 1.7E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS03225 390f3000d015742c71ef3565dfe02452 310 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 270 286 1.7E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS03225 390f3000d015742c71ef3565dfe02452 310 PANTHER PTHR11019:SF45 23 294 1.4E-66 T 13-09-2016 THL1_RS03225 390f3000d015742c71ef3565dfe02452 310 Pfam PF02311 AraC-like ligand binding domain 38 160 1.7E-7 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS03225 390f3000d015742c71ef3565dfe02452 310 SUPERFAMILY SSF46689 242 288 6.27E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS03225 390f3000d015742c71ef3565dfe02452 310 Gene3D G3DSA:2.60.120.280 36 171 7.4E-9 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS03225 390f3000d015742c71ef3565dfe02452 310 Gene3D G3DSA:1.10.10.60 241 289 2.9E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS03225 390f3000d015742c71ef3565dfe02452 310 SUPERFAMILY SSF51182 39 146 4.98E-10 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS16360 2d58019398fac5f491997fec5d8af37a 394 PANTHER PTHR26402 270 284 4.0E-37 T 13-09-2016 THL1_RS16360 2d58019398fac5f491997fec5d8af37a 394 PANTHER PTHR26402 6 136 4.0E-37 T 13-09-2016 THL1_RS16360 2d58019398fac5f491997fec5d8af37a 394 SMART SM00448 6 118 6.8E-35 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS16360 2d58019398fac5f491997fec5d8af37a 394 SMART SM00331 174 391 1.8E-10 T 13-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 THL1_RS16360 2d58019398fac5f491997fec5d8af37a 394 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 201 391 2.4E-32 T 13-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 THL1_RS16360 2d58019398fac5f491997fec5d8af37a 394 Pfam PF00072 Response regulator receiver domain 9 110 3.9E-30 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS16360 2d58019398fac5f491997fec5d8af37a 394 Gene3D G3DSA:3.40.50.2300 6 147 4.4E-38 T 13-09-2016 THL1_RS16360 2d58019398fac5f491997fec5d8af37a 394 SUPERFAMILY SSF52172 5 147 8.97E-40 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS05415 81b5c3875961dc7557d9955f24fd7e5c 102 SUPERFAMILY SSF52091 14 100 1.67E-16 T 13-09-2016 IPR002645 STAS domain THL1_RS05415 81b5c3875961dc7557d9955f24fd7e5c 102 Pfam PF13466 STAS domain 14 94 6.1E-16 T 13-09-2016 IPR002645 STAS domain THL1_RS05415 81b5c3875961dc7557d9955f24fd7e5c 102 Gene3D G3DSA:3.30.750.24 14 101 2.3E-15 T 13-09-2016 IPR002645 STAS domain THL1_RS10160 6cb8d0e4877f4e0aee3b774ea8436c22 192 Pfam PF12019 Type II transport protein GspH 56 176 1.3E-9 T 13-09-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 THL1_RS10160 6cb8d0e4877f4e0aee3b774ea8436c22 192 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 18 166 5.2E-19 T 13-09-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 THL1_RS10160 6cb8d0e4877f4e0aee3b774ea8436c22 192 PRINTS PR00885 Bacterial general secretion pathway protein H signature 16 30 9.4E-12 T 13-09-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 THL1_RS10160 6cb8d0e4877f4e0aee3b774ea8436c22 192 PRINTS PR00885 Bacterial general secretion pathway protein H signature 143 158 9.4E-12 T 13-09-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 THL1_RS10160 6cb8d0e4877f4e0aee3b774ea8436c22 192 PRINTS PR00885 Bacterial general secretion pathway protein H signature 31 45 9.4E-12 T 13-09-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 THL1_RS10160 6cb8d0e4877f4e0aee3b774ea8436c22 192 Gene3D G3DSA:3.55.40.10 51 174 4.0E-31 T 13-09-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 THL1_RS10160 6cb8d0e4877f4e0aee3b774ea8436c22 192 SUPERFAMILY SSF54523 21 98 3.14E-11 T 13-09-2016 THL1_RS10160 6cb8d0e4877f4e0aee3b774ea8436c22 192 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 19 41 9.7E-7 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS10160 6cb8d0e4877f4e0aee3b774ea8436c22 192 Pfam PF13633 Prokaryotic N-terminal methylation site 19 40 1.5E-6 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS11240 9117e886e61c5309eef1586e510b8a2a 230 PANTHER PTHR26402:SF516 6 230 4.7E-151 T 13-09-2016 THL1_RS11240 9117e886e61c5309eef1586e510b8a2a 230 SMART SM00862 151 227 4.5E-25 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS11240 9117e886e61c5309eef1586e510b8a2a 230 PANTHER PTHR26402 6 230 4.7E-151 T 13-09-2016 THL1_RS11240 9117e886e61c5309eef1586e510b8a2a 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 7.6E-23 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS11240 9117e886e61c5309eef1586e510b8a2a 230 Pfam PF00072 Response regulator receiver domain 8 116 7.0E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS11240 9117e886e61c5309eef1586e510b8a2a 230 SUPERFAMILY SSF52172 4 184 1.99E-37 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS11240 9117e886e61c5309eef1586e510b8a2a 230 Gene3D G3DSA:3.40.50.2300 3 125 1.5E-35 T 13-09-2016 THL1_RS11240 9117e886e61c5309eef1586e510b8a2a 230 Gene3D G3DSA:1.10.10.10 129 229 1.7E-29 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11240 9117e886e61c5309eef1586e510b8a2a 230 SMART SM00448 6 116 1.4E-37 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS20450 2e97161bd256fffd6108ed19bc7a2773 296 PIRSF PIRSF000103 1 296 1.8E-78 T 13-09-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 THL1_RS20450 2e97161bd256fffd6108ed19bc7a2773 296 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 5 293 1.7E-131 T 13-09-2016 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|UniPathway: UPA00362 THL1_RS20450 2e97161bd256fffd6108ed19bc7a2773 296 SUPERFAMILY SSF48179 163 294 1.7E-40 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS20450 2e97161bd256fffd6108ed19bc7a2773 296 PANTHER PTHR22981 1 296 8.3E-126 T 13-09-2016 THL1_RS20450 2e97161bd256fffd6108ed19bc7a2773 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 292 5.7E-36 T 13-09-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 THL1_RS20450 2e97161bd256fffd6108ed19bc7a2773 296 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 13-09-2016 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 THL1_RS20450 2e97161bd256fffd6108ed19bc7a2773 296 SUPERFAMILY SSF51735 1 162 8.28E-45 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20450 2e97161bd256fffd6108ed19bc7a2773 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 162 5.3E-50 T 13-09-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 THL1_RS20450 2e97161bd256fffd6108ed19bc7a2773 296 Gene3D G3DSA:1.10.1040.10 164 294 2.9E-47 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS20450 2e97161bd256fffd6108ed19bc7a2773 296 Gene3D G3DSA:3.40.50.720 1 163 3.3E-62 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS14755 a27f937775b2f83495798d468dfd87ca 237 PANTHER PTHR30133:SF1 10 236 4.5E-111 T 13-09-2016 IPR030199 Histidine transport system permease protein HisQ GO:0003333|GO:0016021 THL1_RS14755 a27f937775b2f83495798d468dfd87ca 237 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 122 9.6E-20 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS14755 a27f937775b2f83495798d468dfd87ca 237 Gene3D G3DSA:1.10.3720.10 15 227 1.6E-39 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS14755 a27f937775b2f83495798d468dfd87ca 237 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 38 227 4.3E-21 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS14755 a27f937775b2f83495798d468dfd87ca 237 PANTHER PTHR30133 10 236 4.5E-111 T 13-09-2016 THL1_RS14755 a27f937775b2f83495798d468dfd87ca 237 SUPERFAMILY SSF161098 15 213 5.78E-39 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS05630 0da88aaf2bd371d2c3600beda866af0b 448 PANTHER PTHR23135:SF2 1 448 1.4E-160 T 13-09-2016 THL1_RS05630 0da88aaf2bd371d2c3600beda866af0b 448 Gene3D G3DSA:3.40.50.720 11 95 1.1E-15 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS05630 0da88aaf2bd371d2c3600beda866af0b 448 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 8 447 34.26 T 13-09-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS05630 0da88aaf2bd371d2c3600beda866af0b 448 SUPERFAMILY SSF51984 11 96 4.84E-13 T 13-09-2016 THL1_RS05630 0da88aaf2bd371d2c3600beda866af0b 448 Gene3D G3DSA:3.40.1190.10 98 305 9.6E-65 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05630 0da88aaf2bd371d2c3600beda866af0b 448 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 12 444 6.9E-119 T 13-09-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS05630 0da88aaf2bd371d2c3600beda866af0b 448 Gene3D G3DSA:3.90.190.20 307 443 2.0E-45 T 13-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 THL1_RS05630 0da88aaf2bd371d2c3600beda866af0b 448 PANTHER PTHR23135 1 448 1.4E-160 T 13-09-2016 THL1_RS05630 0da88aaf2bd371d2c3600beda866af0b 448 SUPERFAMILY SSF53623 99 303 3.79E-54 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05630 0da88aaf2bd371d2c3600beda866af0b 448 Pfam PF08245 Mur ligase middle domain 114 285 1.5E-25 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05630 0da88aaf2bd371d2c3600beda866af0b 448 SUPERFAMILY SSF53244 305 447 6.87E-45 T 13-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 THL1_RS03135 be2f6ac542016a5b91e2304490e76346 448 PANTHER PTHR26402:SF515 8 362 6.9E-51 T 13-09-2016 THL1_RS03135 be2f6ac542016a5b91e2304490e76346 448 Pfam PF13487 HD domain 255 315 4.6E-16 T 13-09-2016 THL1_RS03135 be2f6ac542016a5b91e2304490e76346 448 SMART SM00448 8 120 4.0E-23 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS03135 be2f6ac542016a5b91e2304490e76346 448 SUPERFAMILY SSF52172 7 171 5.41E-33 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS03135 be2f6ac542016a5b91e2304490e76346 448 PANTHER PTHR26402 8 362 6.9E-51 T 13-09-2016 THL1_RS03135 be2f6ac542016a5b91e2304490e76346 448 Gene3D G3DSA:3.40.50.2300 9 136 1.2E-30 T 13-09-2016 THL1_RS03135 be2f6ac542016a5b91e2304490e76346 448 Pfam PF00072 Response regulator receiver domain 11 117 1.6E-20 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS03135 be2f6ac542016a5b91e2304490e76346 448 SUPERFAMILY SSF109604 208 362 1.26E-10 T 13-09-2016 THL1_RS27620 3846825cba9178a2e5cb28f72c0e6f54 253 SUPERFAMILY SSF52096 1 248 3.49E-70 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS27620 3846825cba9178a2e5cb28f72c0e6f54 253 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 240 5.1E-48 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS27620 3846825cba9178a2e5cb28f72c0e6f54 253 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 13-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THL1_RS27620 3846825cba9178a2e5cb28f72c0e6f54 253 PANTHER PTHR11941 1 248 8.0E-64 T 13-09-2016 THL1_RS27620 3846825cba9178a2e5cb28f72c0e6f54 253 Gene3D G3DSA:3.90.226.10 1 248 3.4E-72 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20030 ecb7e1bd9bb72d3709c37812b8bc9daa 489 SUPERFAMILY SSF56801 5 480 3.53E-83 T 13-09-2016 THL1_RS20030 ecb7e1bd9bb72d3709c37812b8bc9daa 489 PANTHER PTHR24096 6 445 2.0E-61 T 13-09-2016 THL1_RS20030 ecb7e1bd9bb72d3709c37812b8bc9daa 489 Gene3D G3DSA:3.40.50.980 148 313 2.5E-24 T 13-09-2016 THL1_RS20030 ecb7e1bd9bb72d3709c37812b8bc9daa 489 ProSitePatterns PS00455 Putative AMP-binding domain signature. 141 152 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS20030 ecb7e1bd9bb72d3709c37812b8bc9daa 489 Pfam PF00501 AMP-binding enzyme 14 377 2.0E-51 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS20030 ecb7e1bd9bb72d3709c37812b8bc9daa 489 Gene3D G3DSA:3.40.50.980 5 147 5.3E-17 T 13-09-2016 THL1_RS20030 ecb7e1bd9bb72d3709c37812b8bc9daa 489 Gene3D G3DSA:2.30.38.10 314 367 1.3E-6 T 13-09-2016 THL1_RS13100 795d5df38f7172ec1e540bae13fa5705 263 Gene3D G3DSA:3.40.50.300 3 221 8.4E-63 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS13100 795d5df38f7172ec1e540bae13fa5705 263 SUPERFAMILY SSF52540 5 231 3.51E-69 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS13100 795d5df38f7172ec1e540bae13fa5705 263 SMART SM00382 33 216 6.6E-19 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS13100 795d5df38f7172ec1e540bae13fa5705 263 Pfam PF00005 ABC transporter 24 166 1.8E-29 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS13100 795d5df38f7172ec1e540bae13fa5705 263 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS13100 795d5df38f7172ec1e540bae13fa5705 263 PANTHER PTHR24220:SF361 6 259 2.5E-115 T 13-09-2016 THL1_RS13100 795d5df38f7172ec1e540bae13fa5705 263 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 24 254 6.6E-102 T 13-09-2016 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 THL1_RS13100 795d5df38f7172ec1e540bae13fa5705 263 PANTHER PTHR24220 6 259 2.5E-115 T 13-09-2016 THL1_RS27110 54abb5394f3db18dac26f658b59e8c26 295 SUPERFAMILY SSF64397 2 232 2.49E-68 T 13-09-2016 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 THL1_RS27110 54abb5394f3db18dac26f658b59e8c26 295 Pfam PF01430 Hsp33 protein 3 274 4.9E-80 T 13-09-2016 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 THL1_RS27110 54abb5394f3db18dac26f658b59e8c26 295 PANTHER PTHR30111:SF1 1 289 4.8E-68 T 13-09-2016 THL1_RS27110 54abb5394f3db18dac26f658b59e8c26 295 Gene3D G3DSA:3.90.1280.10 226 283 3.0E-22 T 13-09-2016 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 THL1_RS27110 54abb5394f3db18dac26f658b59e8c26 295 Gene3D G3DSA:3.55.30.10 1 171 2.3E-59 T 13-09-2016 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 THL1_RS27110 54abb5394f3db18dac26f658b59e8c26 295 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 285 30.778 T 13-09-2016 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 THL1_RS27110 54abb5394f3db18dac26f658b59e8c26 295 Gene3D G3DSA:1.10.287.480 179 224 2.4E-20 T 13-09-2016 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain THL1_RS27110 54abb5394f3db18dac26f658b59e8c26 295 PANTHER PTHR30111 1 289 4.8E-68 T 13-09-2016 THL1_RS27110 54abb5394f3db18dac26f658b59e8c26 295 SUPERFAMILY SSF118352 225 283 2.75E-17 T 13-09-2016 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 THL1_RS27110 54abb5394f3db18dac26f658b59e8c26 295 PIRSF PIRSF005261 1 284 5.2E-73 T 13-09-2016 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 Gene3D G3DSA:3.30.70.1430 559 640 4.5E-4 T 13-09-2016 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 Pfam PF00873 AcrB/AcrD/AcrF family 7 1009 4.4E-146 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 SUPERFAMILY SSF82714 710 792 1.7E-13 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 Gene3D G3DSA:3.30.70.1430 43 142 6.0E-18 T 13-09-2016 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 Gene3D G3DSA:3.30.70.1320 158 182 2.1E-5 T 13-09-2016 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 Gene3D G3DSA:3.30.70.1320 273 310 2.1E-5 T 13-09-2016 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 PANTHER PTHR32063:SF18 3 1019 0.0 T 13-09-2016 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 PRINTS PR00702 Acriflavin resistance protein family signature 359 380 1.8E-20 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 1.8E-20 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 1.8E-20 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 1.8E-20 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 PRINTS PR00702 Acriflavin resistance protein family signature 13 37 1.8E-20 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 1.8E-20 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 SUPERFAMILY SSF82866 300 491 3.66E-35 T 13-09-2016 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 SUPERFAMILY SSF82693 271 326 9.94E-14 T 13-09-2016 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 SUPERFAMILY SSF82693 139 185 9.94E-14 T 13-09-2016 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 Gene3D G3DSA:1.20.1640.10 311 496 4.7E-40 T 13-09-2016 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 Gene3D G3DSA:1.10.3850.10 800 1012 2.3E-47 T 13-09-2016 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 Gene3D G3DSA:3.30.2090.10 709 791 2.3E-12 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 Gene3D G3DSA:3.30.2090.10 188 270 2.3E-10 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 SUPERFAMILY SSF82714 188 269 1.26E-11 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 SUPERFAMILY SSF82866 792 1015 7.59E-44 T 13-09-2016 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 SUPERFAMILY SSF82693 43 137 2.22E-15 T 13-09-2016 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 PANTHER PTHR32063 3 1019 0.0 T 13-09-2016 THL1_RS07745 1fc1c8bd222bc63cab917e54f28d3f6d 1024 SUPERFAMILY SSF82693 555 633 1.01E-5 T 13-09-2016 THL1_RS18760 ebd3e88f89e00ca73b2b772609defe8a 363 Pfam PF05426 Alginate lyase 55 295 3.8E-53 T 13-09-2016 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 THL1_RS18760 ebd3e88f89e00ca73b2b772609defe8a 363 SUPERFAMILY SSF48230 41 352 7.6E-48 T 13-09-2016 IPR008929 Chondroitin AC/alginate lyase THL1_RS18760 ebd3e88f89e00ca73b2b772609defe8a 363 Gene3D G3DSA:1.50.10.110 11 353 7.6E-84 T 13-09-2016 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 THL1_RS23465 bbc1bf7dcfbb42387bba79780af20012 741 Pfam PF00593 TonB dependent receptor 473 739 3.8E-15 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS23465 bbc1bf7dcfbb42387bba79780af20012 741 Pfam PF07715 TonB-dependent Receptor Plug Domain 36 138 3.4E-17 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS23465 bbc1bf7dcfbb42387bba79780af20012 741 PANTHER PTHR32552 523 741 3.3E-276 T 13-09-2016 THL1_RS23465 bbc1bf7dcfbb42387bba79780af20012 741 PANTHER PTHR32552:SF30 18 506 3.3E-276 T 13-09-2016 THL1_RS23465 bbc1bf7dcfbb42387bba79780af20012 741 PANTHER PTHR32552:SF30 523 741 3.3E-276 T 13-09-2016 THL1_RS23465 bbc1bf7dcfbb42387bba79780af20012 741 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 37 741 4.1E-85 T 13-09-2016 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 THL1_RS23465 bbc1bf7dcfbb42387bba79780af20012 741 SUPERFAMILY SSF56935 465 741 4.19E-90 T 13-09-2016 THL1_RS23465 bbc1bf7dcfbb42387bba79780af20012 741 SUPERFAMILY SSF56935 25 434 4.19E-90 T 13-09-2016 THL1_RS23465 bbc1bf7dcfbb42387bba79780af20012 741 PANTHER PTHR32552 18 506 3.3E-276 T 13-09-2016 THL1_RS23465 bbc1bf7dcfbb42387bba79780af20012 741 Gene3D G3DSA:2.170.130.10 17 140 3.5E-25 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS23465 bbc1bf7dcfbb42387bba79780af20012 741 Gene3D G3DSA:2.40.170.20 141 741 2.6E-68 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS14045 f0082168697f35fc48652d4a0c1a805b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.4E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14045 f0082168697f35fc48652d4a0c1a805b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.4E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14045 f0082168697f35fc48652d4a0c1a805b 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.4E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14045 f0082168697f35fc48652d4a0c1a805b 301 Gene3D G3DSA:1.10.10.10 2 84 3.3E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14045 f0082168697f35fc48652d4a0c1a805b 301 SUPERFAMILY SSF46785 5 111 3.45E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14045 f0082168697f35fc48652d4a0c1a805b 301 Gene3D G3DSA:3.40.190.10 178 259 2.8E-14 T 13-09-2016 THL1_RS14045 f0082168697f35fc48652d4a0c1a805b 301 Gene3D G3DSA:3.40.190.10 92 177 1.6E-26 T 13-09-2016 THL1_RS14045 f0082168697f35fc48652d4a0c1a805b 301 PANTHER PTHR30537 1 292 4.7E-80 T 13-09-2016 THL1_RS14045 f0082168697f35fc48652d4a0c1a805b 301 SUPERFAMILY SSF53850 88 292 4.16E-34 T 13-09-2016 THL1_RS14045 f0082168697f35fc48652d4a0c1a805b 301 PANTHER PTHR30537:SF26 1 292 4.7E-80 T 13-09-2016 THL1_RS14045 f0082168697f35fc48652d4a0c1a805b 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 1.1E-18 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14045 f0082168697f35fc48652d4a0c1a805b 301 Pfam PF03466 LysR substrate binding domain 88 290 3.2E-32 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS10180 55742d37ce606defd44cd2507e060754 380 Pfam PF12693 GspL periplasmic domain 227 379 6.6E-33 T 13-09-2016 IPR025691 GspL periplasmic domain THL1_RS10180 55742d37ce606defd44cd2507e060754 380 PIRSF PIRSF015761 3 380 3.4E-48 T 13-09-2016 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 THL1_RS10180 55742d37ce606defd44cd2507e060754 380 SUPERFAMILY SSF53067 3 137 2.98E-22 T 13-09-2016 THL1_RS10180 55742d37ce606defd44cd2507e060754 380 Pfam PF05134 Type II secretion system (T2SS), protein L 32 220 1.1E-34 T 13-09-2016 IPR024230 GspL, cytoplasmic actin-ATPase-like domain THL1_RS10180 55742d37ce606defd44cd2507e060754 380 TIGRFAM TIGR01709 typeII_sec_gspL: type II secretion system protein L 33 378 1.6E-66 T 13-09-2016 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 THL1_RS07170 8c0a572eef54a8ce7afa9e4918768c1b 349 Pfam PF01339 CheB methylesterase 158 336 8.1E-61 T 13-09-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS07170 8c0a572eef54a8ce7afa9e4918768c1b 349 SUPERFAMILY SSF52172 3 107 9.53E-27 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS07170 8c0a572eef54a8ce7afa9e4918768c1b 349 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 3 341 41.697 T 13-09-2016 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS07170 8c0a572eef54a8ce7afa9e4918768c1b 349 Gene3D G3DSA:3.40.50.180 154 342 3.4E-82 T 13-09-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS07170 8c0a572eef54a8ce7afa9e4918768c1b 349 PANTHER PTHR24421:SF21 1 343 7.1E-163 T 13-09-2016 THL1_RS07170 8c0a572eef54a8ce7afa9e4918768c1b 349 PIRSF PIRSF000876 1 345 1.9E-135 T 13-09-2016 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS07170 8c0a572eef54a8ce7afa9e4918768c1b 349 Pfam PF00072 Response regulator receiver domain 5 107 8.1E-23 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS07170 8c0a572eef54a8ce7afa9e4918768c1b 349 SUPERFAMILY SSF52738 154 342 9.68E-72 T 13-09-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS07170 8c0a572eef54a8ce7afa9e4918768c1b 349 SMART SM00448 3 118 4.1E-21 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS07170 8c0a572eef54a8ce7afa9e4918768c1b 349 Gene3D G3DSA:3.40.50.2300 3 107 9.2E-27 T 13-09-2016 THL1_RS07170 8c0a572eef54a8ce7afa9e4918768c1b 349 PANTHER PTHR24421 1 343 7.1E-163 T 13-09-2016 THL1_RS26510 75c096320b22c83dac822adc7ee88355 402 PANTHER PTHR22642 4 399 2.0E-155 T 13-09-2016 THL1_RS26510 75c096320b22c83dac822adc7ee88355 402 Hamap MF_00372 Imidazolonepropionase [hutI]. 2 399 43.383 T 13-09-2016 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 THL1_RS26510 75c096320b22c83dac822adc7ee88355 402 SUPERFAMILY SSF51338 361 398 7.46E-31 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS26510 75c096320b22c83dac822adc7ee88355 402 SUPERFAMILY SSF51338 1 60 7.46E-31 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS26510 75c096320b22c83dac822adc7ee88355 402 Gene3D G3DSA:2.30.40.10 346 380 6.1E-5 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS26510 75c096320b22c83dac822adc7ee88355 402 Gene3D G3DSA:3.20.20.140 73 345 1.5E-45 T 13-09-2016 THL1_RS26510 75c096320b22c83dac822adc7ee88355 402 TIGRFAM TIGR01224 hutI: imidazolonepropionase 22 397 1.4E-152 T 13-09-2016 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 THL1_RS26510 75c096320b22c83dac822adc7ee88355 402 Pfam PF01979 Amidohydrolase family 57 397 6.2E-25 T 13-09-2016 IPR006680 Amidohydrolase-related GO:0016787 THL1_RS26510 75c096320b22c83dac822adc7ee88355 402 Gene3D G3DSA:2.30.40.10 18 72 7.3E-15 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS26510 75c096320b22c83dac822adc7ee88355 402 PANTHER PTHR22642:SF1 4 399 2.0E-155 T 13-09-2016 THL1_RS26510 75c096320b22c83dac822adc7ee88355 402 SUPERFAMILY SSF51556 60 360 2.53E-89 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS02810 12455da66a8a7d9c4ebdb12d59213411 325 Hamap MF_01083 Protein CsiD [csiD]. 1 325 75.241 T 13-09-2016 IPR015038 Uncharacterised protein family CsiD GO:0005506 THL1_RS02810 12455da66a8a7d9c4ebdb12d59213411 325 Gene3D G3DSA:3.60.130.10 18 319 2.2E-118 T 13-09-2016 THL1_RS02810 12455da66a8a7d9c4ebdb12d59213411 325 ProDom PD135861 METAL-BINDING IRON CSID GAB CYTOPLASMIC 3D-STRUCTURE HOMOLOG DIRECT SEQUENCING 20 312 3.0E-162 T 13-09-2016 IPR015038 Uncharacterised protein family CsiD GO:0005506 THL1_RS02810 12455da66a8a7d9c4ebdb12d59213411 325 SUPERFAMILY SSF51197 17 313 7.78E-88 T 13-09-2016 THL1_RS02810 12455da66a8a7d9c4ebdb12d59213411 325 Pfam PF08943 CsiD 21 313 5.8E-143 T 13-09-2016 IPR015038 Uncharacterised protein family CsiD GO:0005506 THL1_RS07785 12455da66a8a7d9c4ebdb12d59213411 325 Hamap MF_01083 Protein CsiD [csiD]. 1 325 75.241 T 13-09-2016 IPR015038 Uncharacterised protein family CsiD GO:0005506 THL1_RS07785 12455da66a8a7d9c4ebdb12d59213411 325 Gene3D G3DSA:3.60.130.10 18 319 2.2E-118 T 13-09-2016 THL1_RS07785 12455da66a8a7d9c4ebdb12d59213411 325 ProDom PD135861 METAL-BINDING IRON CSID GAB CYTOPLASMIC 3D-STRUCTURE HOMOLOG DIRECT SEQUENCING 20 312 3.0E-162 T 13-09-2016 IPR015038 Uncharacterised protein family CsiD GO:0005506 THL1_RS07785 12455da66a8a7d9c4ebdb12d59213411 325 SUPERFAMILY SSF51197 17 313 7.78E-88 T 13-09-2016 THL1_RS07785 12455da66a8a7d9c4ebdb12d59213411 325 Pfam PF08943 CsiD 21 313 5.8E-143 T 13-09-2016 IPR015038 Uncharacterised protein family CsiD GO:0005506 THL1_RS02550 697c65b76dc1a8675d4dfb3f08cd0da3 189 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 5 187 1.7E-54 T 13-09-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 THL1_RS02550 697c65b76dc1a8675d4dfb3f08cd0da3 189 Pfam PF02660 Glycerol-3-phosphate acyltransferase 8 181 1.1E-52 T 13-09-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 THL1_RS02550 697c65b76dc1a8675d4dfb3f08cd0da3 189 PANTHER PTHR30309 1 189 8.5E-71 T 13-09-2016 THL1_RS02550 697c65b76dc1a8675d4dfb3f08cd0da3 189 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 4 189 18.621 T 13-09-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 THL1_RS02550 697c65b76dc1a8675d4dfb3f08cd0da3 189 SMART SM01207 7 182 8.5E-83 T 13-09-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 THL1_RS02550 697c65b76dc1a8675d4dfb3f08cd0da3 189 PANTHER PTHR30309:SF0 1 189 8.5E-71 T 13-09-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 THL1_RS13630 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055:SF3 1 317 3.6E-58 T 13-09-2016 THL1_RS13630 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF01548 Transposase 5 151 1.1E-28 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS13630 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055 1 317 3.6E-58 T 13-09-2016 THL1_RS13630 e014d200a4bf9ab5c2b9e12796ef73ef 324 Gene3D G3DSA:1.10.357.10 109 215 8.2E-4 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS13630 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 196 279 4.3E-24 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS27300 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055:SF3 1 317 3.6E-58 T 13-09-2016 THL1_RS27300 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF01548 Transposase 5 151 1.1E-28 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS27300 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055 1 317 3.6E-58 T 13-09-2016 THL1_RS27300 e014d200a4bf9ab5c2b9e12796ef73ef 324 Gene3D G3DSA:1.10.357.10 109 215 8.2E-4 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS27300 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 196 279 4.3E-24 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS12980 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055:SF3 1 317 3.6E-58 T 13-09-2016 THL1_RS12980 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF01548 Transposase 5 151 1.1E-28 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS12980 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055 1 317 3.6E-58 T 13-09-2016 THL1_RS12980 e014d200a4bf9ab5c2b9e12796ef73ef 324 Gene3D G3DSA:1.10.357.10 109 215 8.2E-4 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS12980 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 196 279 4.3E-24 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS02015 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055:SF3 1 317 3.6E-58 T 13-09-2016 THL1_RS02015 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF01548 Transposase 5 151 1.1E-28 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS02015 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055 1 317 3.6E-58 T 13-09-2016 THL1_RS02015 e014d200a4bf9ab5c2b9e12796ef73ef 324 Gene3D G3DSA:1.10.357.10 109 215 8.2E-4 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS02015 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 196 279 4.3E-24 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS06510 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055:SF3 1 317 3.6E-58 T 13-09-2016 THL1_RS06510 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF01548 Transposase 5 151 1.1E-28 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS06510 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055 1 317 3.6E-58 T 13-09-2016 THL1_RS06510 e014d200a4bf9ab5c2b9e12796ef73ef 324 Gene3D G3DSA:1.10.357.10 109 215 8.2E-4 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS06510 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 196 279 4.3E-24 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS08515 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055:SF3 1 317 3.6E-58 T 13-09-2016 THL1_RS08515 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF01548 Transposase 5 151 1.1E-28 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS08515 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055 1 317 3.6E-58 T 13-09-2016 THL1_RS08515 e014d200a4bf9ab5c2b9e12796ef73ef 324 Gene3D G3DSA:1.10.357.10 109 215 8.2E-4 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS08515 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 196 279 4.3E-24 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS01070 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055:SF3 1 317 3.6E-58 T 13-09-2016 THL1_RS01070 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF01548 Transposase 5 151 1.1E-28 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS01070 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055 1 317 3.6E-58 T 13-09-2016 THL1_RS01070 e014d200a4bf9ab5c2b9e12796ef73ef 324 Gene3D G3DSA:1.10.357.10 109 215 8.2E-4 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS01070 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 196 279 4.3E-24 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS13665 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055:SF3 1 317 3.6E-58 T 13-09-2016 THL1_RS13665 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF01548 Transposase 5 151 1.1E-28 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS13665 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055 1 317 3.6E-58 T 13-09-2016 THL1_RS13665 e014d200a4bf9ab5c2b9e12796ef73ef 324 Gene3D G3DSA:1.10.357.10 109 215 8.2E-4 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS13665 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 196 279 4.3E-24 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS25220 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055:SF3 1 317 3.6E-58 T 13-09-2016 THL1_RS25220 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF01548 Transposase 5 151 1.1E-28 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS25220 e014d200a4bf9ab5c2b9e12796ef73ef 324 PANTHER PTHR33055 1 317 3.6E-58 T 13-09-2016 THL1_RS25220 e014d200a4bf9ab5c2b9e12796ef73ef 324 Gene3D G3DSA:1.10.357.10 109 215 8.2E-4 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS25220 e014d200a4bf9ab5c2b9e12796ef73ef 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 196 279 4.3E-24 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS13110 0ff2750e43fe7aea1bc8a828963ddc1d 427 PANTHER PTHR30024:SF7 19 427 1.1E-144 T 13-09-2016 THL1_RS13110 0ff2750e43fe7aea1bc8a828963ddc1d 427 Gene3D G3DSA:3.40.190.10 181 279 3.5E-7 T 13-09-2016 THL1_RS13110 0ff2750e43fe7aea1bc8a828963ddc1d 427 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 13 48 2.5E-4 T 13-09-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THL1_RS13110 0ff2750e43fe7aea1bc8a828963ddc1d 427 Pfam PF13379 NMT1-like family 52 302 3.3E-106 T 13-09-2016 THL1_RS13110 0ff2750e43fe7aea1bc8a828963ddc1d 427 SUPERFAMILY SSF53850 56 291 2.17E-29 T 13-09-2016 THL1_RS13110 0ff2750e43fe7aea1bc8a828963ddc1d 427 PANTHER PTHR30024 19 427 1.1E-144 T 13-09-2016 THL1_RS23875 90001dd0f98f94bf232a1e76be1fc05b 212 Gene3D G3DSA:3.40.50.2020 7 208 3.6E-72 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS23875 90001dd0f98f94bf232a1e76be1fc05b 212 PANTHER PTHR10285 8 197 3.9E-91 T 13-09-2016 THL1_RS23875 90001dd0f98f94bf232a1e76be1fc05b 212 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 208 44.016 T 13-09-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183|UniPathway: UPA00574 THL1_RS23875 90001dd0f98f94bf232a1e76be1fc05b 212 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 208 2.8E-87 T 13-09-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183|UniPathway: UPA00574 THL1_RS23875 90001dd0f98f94bf232a1e76be1fc05b 212 Pfam PF14681 Uracil phosphoribosyltransferase 7 207 1.0E-62 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS23875 90001dd0f98f94bf232a1e76be1fc05b 212 SUPERFAMILY SSF53271 5 206 6.29E-66 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS00730 b4c60e912b516f334c55cffea33cf750 321 Gene3D G3DSA:1.10.10.10 3 81 1.2E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00730 b4c60e912b516f334c55cffea33cf750 321 PANTHER PTHR30126 1 307 3.9E-133 T 13-09-2016 THL1_RS00730 b4c60e912b516f334c55cffea33cf750 321 Gene3D G3DSA:3.40.190.10 82 165 5.1E-7 T 13-09-2016 THL1_RS00730 b4c60e912b516f334c55cffea33cf750 321 Gene3D G3DSA:3.40.190.10 166 261 1.9E-18 T 13-09-2016 THL1_RS00730 b4c60e912b516f334c55cffea33cf750 321 PANTHER PTHR30126:SF26 1 307 3.9E-133 T 13-09-2016 THL1_RS00730 b4c60e912b516f334c55cffea33cf750 321 SUPERFAMILY SSF46785 3 112 2.81E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00730 b4c60e912b516f334c55cffea33cf750 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.0E-17 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS00730 b4c60e912b516f334c55cffea33cf750 321 Pfam PF03466 LysR substrate binding domain 90 293 8.2E-42 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS00730 b4c60e912b516f334c55cffea33cf750 321 SUPERFAMILY SSF53850 90 297 5.07E-41 T 13-09-2016 THL1_RS22085 d3ba5562d4cf05e9be7b5d84976e6c54 274 PANTHER PTHR26312:SF74 41 55 5.9E-50 T 13-09-2016 THL1_RS22085 d3ba5562d4cf05e9be7b5d84976e6c54 274 Gene3D G3DSA:1.25.40.10 155 264 2.5E-14 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS22085 d3ba5562d4cf05e9be7b5d84976e6c54 274 Pfam PF16331 TolA binding protein trimerisation 61 116 2.6E-13 T 13-09-2016 IPR032519 YbgF, trimerisation domain GO:0070206 THL1_RS22085 d3ba5562d4cf05e9be7b5d84976e6c54 274 Pfam PF13525 Outer membrane lipoprotein 153 269 1.6E-10 T 13-09-2016 THL1_RS22085 d3ba5562d4cf05e9be7b5d84976e6c54 274 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 153 270 3.8E-42 T 13-09-2016 IPR014162 Tol-Pal system, YbgF THL1_RS22085 d3ba5562d4cf05e9be7b5d84976e6c54 274 PANTHER PTHR26312 164 271 5.9E-50 T 13-09-2016 THL1_RS22085 d3ba5562d4cf05e9be7b5d84976e6c54 274 PANTHER PTHR26312 41 55 5.9E-50 T 13-09-2016 THL1_RS22085 d3ba5562d4cf05e9be7b5d84976e6c54 274 SUPERFAMILY SSF48452 149 267 7.01E-14 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS22085 d3ba5562d4cf05e9be7b5d84976e6c54 274 PANTHER PTHR26312:SF74 164 271 5.9E-50 T 13-09-2016 THL1_RS21315 41875069cd84131866d17003c17ca763 474 Pfam PF13180 PDZ domain 271 359 5.0E-17 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS21315 41875069cd84131866d17003c17ca763 474 Pfam PF13180 PDZ domain 385 466 8.9E-11 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS21315 41875069cd84131866d17003c17ca763 474 Gene3D G3DSA:2.40.10.10 163 271 3.0E-45 T 13-09-2016 THL1_RS21315 41875069cd84131866d17003c17ca763 474 PANTHER PTHR22939:SF98 76 386 3.5E-147 T 13-09-2016 THL1_RS21315 41875069cd84131866d17003c17ca763 474 Gene3D G3DSA:2.40.10.10 22 48 5.4E-38 T 13-09-2016 THL1_RS21315 41875069cd84131866d17003c17ca763 474 Gene3D G3DSA:2.40.10.10 85 162 5.4E-38 T 13-09-2016 THL1_RS21315 41875069cd84131866d17003c17ca763 474 PANTHER PTHR22939:SF98 24 50 3.5E-147 T 13-09-2016 THL1_RS21315 41875069cd84131866d17003c17ca763 474 SUPERFAMILY SSF50156 385 472 5.39E-15 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS21315 41875069cd84131866d17003c17ca763 474 Gene3D G3DSA:2.30.42.10 272 368 6.1E-30 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS21315 41875069cd84131866d17003c17ca763 474 Gene3D G3DSA:2.30.42.10 385 474 3.4E-20 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS21315 41875069cd84131866d17003c17ca763 474 SMART SM00228 384 463 1.4E-11 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS21315 41875069cd84131866d17003c17ca763 474 SMART SM00228 270 352 1.9E-16 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS21315 41875069cd84131866d17003c17ca763 474 PANTHER PTHR22939 76 386 3.5E-147 T 13-09-2016 THL1_RS21315 41875069cd84131866d17003c17ca763 474 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 28 470 6.3E-161 T 13-09-2016 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 THL1_RS21315 41875069cd84131866d17003c17ca763 474 Pfam PF13365 Trypsin-like peptidase domain 98 231 1.1E-35 T 13-09-2016 THL1_RS21315 41875069cd84131866d17003c17ca763 474 PANTHER PTHR22939 24 50 3.5E-147 T 13-09-2016 THL1_RS21315 41875069cd84131866d17003c17ca763 474 SUPERFAMILY SSF50156 228 352 2.89E-27 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS21315 41875069cd84131866d17003c17ca763 474 PRINTS PR00834 HtrA/DegQ protease family signature 224 241 6.7E-53 T 13-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THL1_RS21315 41875069cd84131866d17003c17ca763 474 PRINTS PR00834 HtrA/DegQ protease family signature 128 148 6.7E-53 T 13-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THL1_RS21315 41875069cd84131866d17003c17ca763 474 PRINTS PR00834 HtrA/DegQ protease family signature 168 192 6.7E-53 T 13-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THL1_RS21315 41875069cd84131866d17003c17ca763 474 PRINTS PR00834 HtrA/DegQ protease family signature 310 322 6.7E-53 T 13-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THL1_RS21315 41875069cd84131866d17003c17ca763 474 PRINTS PR00834 HtrA/DegQ protease family signature 107 119 6.7E-53 T 13-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THL1_RS21315 41875069cd84131866d17003c17ca763 474 PRINTS PR00834 HtrA/DegQ protease family signature 202 219 6.7E-53 T 13-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THL1_RS21315 41875069cd84131866d17003c17ca763 474 SUPERFAMILY SSF50494 27 262 6.39E-69 T 13-09-2016 IPR009003 Peptidase S1, PA clan THL1_RS21625 7ab1b038bd561003f53c58bb4cddfdf5 369 PANTHER PTHR24220 8 247 4.6E-126 T 13-09-2016 THL1_RS21625 7ab1b038bd561003f53c58bb4cddfdf5 369 Gene3D G3DSA:3.40.50.300 2 237 5.8E-69 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21625 7ab1b038bd561003f53c58bb4cddfdf5 369 SMART SM00382 31 214 4.5E-15 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS21625 7ab1b038bd561003f53c58bb4cddfdf5 369 Pfam PF00005 ABC transporter 23 164 2.3E-31 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS21625 7ab1b038bd561003f53c58bb4cddfdf5 369 SUPERFAMILY SSF52540 6 242 3.1E-75 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21625 7ab1b038bd561003f53c58bb4cddfdf5 369 PANTHER PTHR24220:SF282 8 247 4.6E-126 T 13-09-2016 THL1_RS21625 7ab1b038bd561003f53c58bb4cddfdf5 369 Pfam PF08402 TOBE domain 276 345 3.8E-10 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS21625 7ab1b038bd561003f53c58bb4cddfdf5 369 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS21625 7ab1b038bd561003f53c58bb4cddfdf5 369 SUPERFAMILY SSF50331 263 346 8.16E-13 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS19155 d077ca91de2721441e25162709d3b582 316 Gene3D G3DSA:1.10.10.10 10 89 1.4E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19155 d077ca91de2721441e25162709d3b582 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 6.6E-21 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19155 d077ca91de2721441e25162709d3b582 316 SUPERFAMILY SSF53850 99 307 4.34E-29 T 13-09-2016 THL1_RS19155 d077ca91de2721441e25162709d3b582 316 Gene3D G3DSA:3.40.190.10 171 270 1.0E-18 T 13-09-2016 THL1_RS19155 d077ca91de2721441e25162709d3b582 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 4.4E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19155 d077ca91de2721441e25162709d3b582 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 4.4E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19155 d077ca91de2721441e25162709d3b582 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 4.4E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19155 d077ca91de2721441e25162709d3b582 316 PANTHER PTHR30537 3 310 9.1E-80 T 13-09-2016 THL1_RS19155 d077ca91de2721441e25162709d3b582 316 SUPERFAMILY SSF46785 8 87 8.72E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19155 d077ca91de2721441e25162709d3b582 316 Gene3D G3DSA:3.40.190.10 99 170 1.7E-5 T 13-09-2016 THL1_RS19155 d077ca91de2721441e25162709d3b582 316 PANTHER PTHR30537:SF26 3 310 9.1E-80 T 13-09-2016 THL1_RS19155 d077ca91de2721441e25162709d3b582 316 Pfam PF03466 LysR substrate binding domain 101 303 1.2E-26 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS22290 7dd9c9d4953fb7b1b813e9ca7f23995c 748 Gene3D G3DSA:3.30.460.10 205 351 2.3E-54 T 13-09-2016 THL1_RS22290 7dd9c9d4953fb7b1b813e9ca7f23995c 748 SUPERFAMILY SSF81271 407 475 1.5E-22 T 13-09-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 THL1_RS22290 7dd9c9d4953fb7b1b813e9ca7f23995c 748 Pfam PF13328 HD domain 40 202 1.5E-45 T 13-09-2016 IPR003607 HD/PDEase domain THL1_RS22290 7dd9c9d4953fb7b1b813e9ca7f23995c 748 Pfam PF13291 ACT domain 667 744 1.8E-18 T 13-09-2016 IPR002912 ACT domain GO:0008152|GO:0016597 THL1_RS22290 7dd9c9d4953fb7b1b813e9ca7f23995c 748 Pfam PF02824 TGS domain 416 475 5.9E-23 T 13-09-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 THL1_RS22290 7dd9c9d4953fb7b1b813e9ca7f23995c 748 PANTHER PTHR21262 69 747 0.0 T 13-09-2016 THL1_RS22290 7dd9c9d4953fb7b1b813e9ca7f23995c 748 SUPERFAMILY SSF109604 18 218 6.91E-49 T 13-09-2016 THL1_RS22290 7dd9c9d4953fb7b1b813e9ca7f23995c 748 SMART SM00954 262 372 4.4E-67 T 13-09-2016 IPR007685 RelA/SpoT GO:0015969 THL1_RS22290 7dd9c9d4953fb7b1b813e9ca7f23995c 748 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 67 743 2.6E-189 T 13-09-2016 IPR004811 RelA/SpoT family GO:0015969 THL1_RS22290 7dd9c9d4953fb7b1b813e9ca7f23995c 748 Gene3D G3DSA:3.30.70.260 668 743 2.8E-17 T 13-09-2016 THL1_RS22290 7dd9c9d4953fb7b1b813e9ca7f23995c 748 Gene3D G3DSA:3.10.20.30 416 477 1.4E-25 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS22290 7dd9c9d4953fb7b1b813e9ca7f23995c 748 Pfam PF04607 Region found in RelA / SpoT proteins 262 370 4.6E-38 T 13-09-2016 IPR007685 RelA/SpoT GO:0015969 THL1_RS22290 7dd9c9d4953fb7b1b813e9ca7f23995c 748 SUPERFAMILY SSF81301 207 420 2.94E-64 T 13-09-2016 THL1_RS22290 7dd9c9d4953fb7b1b813e9ca7f23995c 748 SUPERFAMILY SSF55021 668 744 6.66E-15 T 13-09-2016 THL1_RS22290 7dd9c9d4953fb7b1b813e9ca7f23995c 748 PANTHER PTHR21262:SF5 69 747 0.0 T 13-09-2016 THL1_RS21945 6a159ea7667a21ee47dd63d57204ca7d 943 Gene3D G3DSA:3.40.50.980 291 454 2.7E-40 T 13-09-2016 THL1_RS21945 6a159ea7667a21ee47dd63d57204ca7d 943 Gene3D G3DSA:2.30.38.10 491 563 1.9E-18 T 13-09-2016 THL1_RS21945 6a159ea7667a21ee47dd63d57204ca7d 943 Pfam PF01553 Acyltransferase 759 883 5.5E-22 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS21945 6a159ea7667a21ee47dd63d57204ca7d 943 ProSitePatterns PS00455 Putative AMP-binding domain signature. 286 297 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS21945 6a159ea7667a21ee47dd63d57204ca7d 943 SUPERFAMILY SSF69593 717 913 7.19E-33 T 13-09-2016 THL1_RS21945 6a159ea7667a21ee47dd63d57204ca7d 943 Gene3D G3DSA:3.30.300.30 564 669 9.8E-14 T 13-09-2016 THL1_RS21945 6a159ea7667a21ee47dd63d57204ca7d 943 Gene3D G3DSA:1.10.1200.10 41 94 7.6E-10 T 13-09-2016 IPR009081 Phosphopantetheine binding ACP domain THL1_RS21945 6a159ea7667a21ee47dd63d57204ca7d 943 SMART SM00823 Phosphopantetheine attachment site 23 96 0.0026 T 13-09-2016 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 THL1_RS21945 6a159ea7667a21ee47dd63d57204ca7d 943 Pfam PF00501 AMP-binding enzyme 131 570 3.1E-81 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS21945 6a159ea7667a21ee47dd63d57204ca7d 943 Pfam PF00550 Phosphopantetheine attachment site 29 90 2.6E-7 T 13-09-2016 IPR009081 Phosphopantetheine binding ACP domain THL1_RS21945 6a159ea7667a21ee47dd63d57204ca7d 943 SUPERFAMILY SSF47336 19 95 8.77E-11 T 13-09-2016 IPR009081 Phosphopantetheine binding ACP domain THL1_RS21945 6a159ea7667a21ee47dd63d57204ca7d 943 SUPERFAMILY SSF56801 487 673 1.7E-112 T 13-09-2016 THL1_RS21945 6a159ea7667a21ee47dd63d57204ca7d 943 SUPERFAMILY SSF56801 121 460 1.7E-112 T 13-09-2016 THL1_RS21945 6a159ea7667a21ee47dd63d57204ca7d 943 Gene3D G3DSA:3.40.50.980 124 290 3.6E-34 T 13-09-2016 THL1_RS21945 6a159ea7667a21ee47dd63d57204ca7d 943 Gene3D G3DSA:3.40.1130.10 763 916 8.1E-16 T 13-09-2016 THL1_RS21945 6a159ea7667a21ee47dd63d57204ca7d 943 SMART SM00563 772 886 2.7E-33 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS21945 6a159ea7667a21ee47dd63d57204ca7d 943 PANTHER PTHR22754 124 721 5.3E-144 T 13-09-2016 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 305 5.7E-64 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 Gene3D G3DSA:3.50.50.60 2 110 2.1E-32 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 Gene3D G3DSA:3.30.390.30 324 408 4.6E-34 T 13-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 6.5E-18 T 13-09-2016 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 6.5E-18 T 13-09-2016 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 6.5E-18 T 13-09-2016 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 6.5E-18 T 13-09-2016 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 6.5E-18 T 13-09-2016 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 Pfam PF14759 Reductase C-terminal 324 408 9.4E-33 T 13-09-2016 IPR028202 Reductase, C-terminal THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 PANTHER PTHR22912:SF180 2 393 2.5E-103 T 13-09-2016 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 SUPERFAMILY SSF51905 148 314 4.35E-30 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 Gene3D G3DSA:3.50.50.60 111 314 4.6E-46 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 SUPERFAMILY SSF55424 317 408 5.36E-32 T 13-09-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 SUPERFAMILY SSF51905 6 194 8.03E-45 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.2E-14 T 13-09-2016 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 1.2E-14 T 13-09-2016 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 1.2E-14 T 13-09-2016 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 1.2E-14 T 13-09-2016 THL1_RS20885 3a0a16f59073bf2ff34357cc7f7471f7 409 PANTHER PTHR22912 2 393 2.5E-103 T 13-09-2016 THL1_RS28425 3e7162a8d4d39648ef234a69e5fa421e 286 Gene3D G3DSA:3.40.1380.10 64 191 2.0E-42 T 13-09-2016 THL1_RS28425 3e7162a8d4d39648ef234a69e5fa421e 286 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 286 6.5E-106 T 13-09-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 THL1_RS28425 3e7162a8d4d39648ef234a69e5fa421e 286 Gene3D G3DSA:1.10.287.80 201 234 9.6E-38 T 13-09-2016 THL1_RS28425 3e7162a8d4d39648ef234a69e5fa421e 286 Gene3D G3DSA:1.10.287.80 19 60 9.6E-38 T 13-09-2016 THL1_RS28425 3e7162a8d4d39648ef234a69e5fa421e 286 PANTHER PTHR11693 1 286 8.7E-131 T 13-09-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 THL1_RS28425 3e7162a8d4d39648ef234a69e5fa421e 286 SUPERFAMILY SSF52943 2 286 1.83E-94 T 13-09-2016 IPR023633 ATPase, F1 complex, gamma subunit domain THL1_RS28425 3e7162a8d4d39648ef234a69e5fa421e 286 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 286 36.396 T 13-09-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 THL1_RS28425 3e7162a8d4d39648ef234a69e5fa421e 286 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 272 285 - T 13-09-2016 IPR023632 ATPase, F1 complex, gamma subunit conserved site THL1_RS28425 3e7162a8d4d39648ef234a69e5fa421e 286 PRINTS PR00126 ATP synthase gamma subunit signature 264 285 5.4E-37 T 13-09-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 THL1_RS28425 3e7162a8d4d39648ef234a69e5fa421e 286 PRINTS PR00126 ATP synthase gamma subunit signature 233 252 5.4E-37 T 13-09-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 THL1_RS28425 3e7162a8d4d39648ef234a69e5fa421e 286 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 5.4E-37 T 13-09-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 THL1_RS28425 3e7162a8d4d39648ef234a69e5fa421e 286 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 5.4E-37 T 13-09-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 THL1_RS28425 3e7162a8d4d39648ef234a69e5fa421e 286 Gene3D G3DSA:1.10.287.80 235 281 2.6E-31 T 13-09-2016 THL1_RS28425 3e7162a8d4d39648ef234a69e5fa421e 286 Pfam PF00231 ATP synthase 5 285 1.7E-90 T 13-09-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 THL1_RS04790 017176d46ef074140414c7484bb9fdbb 836 PANTHER PTHR10046:SF46 149 760 6.2E-145 T 13-09-2016 THL1_RS04790 017176d46ef074140414c7484bb9fdbb 836 Gene3D G3DSA:3.30.230.10 557 755 1.6E-29 T 13-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THL1_RS04790 017176d46ef074140414c7484bb9fdbb 836 SUPERFAMILY SSF54211 564 756 9.1E-34 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS04790 017176d46ef074140414c7484bb9fdbb 836 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 676 695 1.7E-12 T 13-09-2016 THL1_RS04790 017176d46ef074140414c7484bb9fdbb 836 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 646 665 1.7E-12 T 13-09-2016 THL1_RS04790 017176d46ef074140414c7484bb9fdbb 836 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 66 85 1.7E-12 T 13-09-2016 THL1_RS04790 017176d46ef074140414c7484bb9fdbb 836 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 565 581 1.7E-12 T 13-09-2016 THL1_RS04790 017176d46ef074140414c7484bb9fdbb 836 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 706 724 1.7E-12 T 13-09-2016 THL1_RS04790 017176d46ef074140414c7484bb9fdbb 836 Gene3D G3DSA:3.40.50.300 35 92 2.1E-9 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04790 017176d46ef074140414c7484bb9fdbb 836 Gene3D G3DSA:3.40.50.300 297 392 2.1E-9 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04790 017176d46ef074140414c7484bb9fdbb 836 PANTHER PTHR10046 149 760 6.2E-145 T 13-09-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 THL1_RS04790 017176d46ef074140414c7484bb9fdbb 836 Pfam PF13654 AAA domain 30 539 1.1E-174 T 13-09-2016 THL1_RS04790 017176d46ef074140414c7484bb9fdbb 836 SUPERFAMILY SSF52540 35 109 7.32E-12 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04790 017176d46ef074140414c7484bb9fdbb 836 SUPERFAMILY SSF52540 306 534 7.32E-12 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04790 017176d46ef074140414c7484bb9fdbb 836 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 649 752 5.5E-7 T 13-09-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 THL1_RS08330 f5605af076abe7949cfe4ec4912e86e6 581 Gene3D G3DSA:3.40.50.2300 117 219 9.5E-41 T 13-09-2016 THL1_RS08330 f5605af076abe7949cfe4ec4912e86e6 581 Gene3D G3DSA:3.40.50.2300 1 102 8.7E-21 T 13-09-2016 THL1_RS08330 f5605af076abe7949cfe4ec4912e86e6 581 SUPERFAMILY SSF52794 2 97 1.44E-21 T 13-09-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 THL1_RS08330 f5605af076abe7949cfe4ec4912e86e6 581 PANTHER PTHR30505 1 581 3.4E-262 T 13-09-2016 THL1_RS08330 f5605af076abe7949cfe4ec4912e86e6 581 PANTHER PTHR30505:SF0 1 581 3.4E-262 T 13-09-2016 THL1_RS08330 f5605af076abe7949cfe4ec4912e86e6 581 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 91 6.7E-9 T 13-09-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 THL1_RS08330 f5605af076abe7949cfe4ec4912e86e6 581 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 122 208 5.7E-19 T 13-09-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 THL1_RS08330 f5605af076abe7949cfe4ec4912e86e6 581 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 234 566 5.8E-142 T 13-09-2016 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 THL1_RS08330 f5605af076abe7949cfe4ec4912e86e6 581 SUPERFAMILY SSF52794 119 218 1.92E-35 T 13-09-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 THL1_RS08330 f5605af076abe7949cfe4ec4912e86e6 581 Pfam PF02378 Phosphotransferase system, EIIC 247 510 1.4E-18 T 13-09-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 THL1_RS08330 f5605af076abe7949cfe4ec4912e86e6 581 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 121 204 7.3E-33 T 13-09-2016 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 THL1_RS10530 585a77ec22f838259ef1baa095357b32 404 Gene3D G3DSA:2.170.190.11 55 134 1.5E-27 T 13-09-2016 THL1_RS10530 585a77ec22f838259ef1baa095357b32 404 Gene3D G3DSA:3.40.980.10 167 333 1.3E-57 T 13-09-2016 IPR001453 MoaB/Mog domain THL1_RS10530 585a77ec22f838259ef1baa095357b32 404 SUPERFAMILY SSF63867 331 401 1.2E-15 T 13-09-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 THL1_RS10530 585a77ec22f838259ef1baa095357b32 404 SUPERFAMILY SSF63882 7 180 1.24E-53 T 13-09-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 THL1_RS10530 585a77ec22f838259ef1baa095357b32 404 Pfam PF03453 MoeA N-terminal region (domain I and II) 11 171 5.4E-36 T 13-09-2016 IPR005110 MoeA, N-terminal and linker domain GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 THL1_RS10530 585a77ec22f838259ef1baa095357b32 404 PANTHER PTHR10192:SF17 1 402 6.0E-186 T 13-09-2016 THL1_RS10530 585a77ec22f838259ef1baa095357b32 404 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 182 316 7.6E-29 T 13-09-2016 IPR001453 MoaB/Mog domain THL1_RS10530 585a77ec22f838259ef1baa095357b32 404 SMART SM00852 184 320 2.2E-41 T 13-09-2016 IPR001453 MoaB/Mog domain THL1_RS10530 585a77ec22f838259ef1baa095357b32 404 Gene3D G3DSA:2.40.340.10 335 400 4.4E-12 T 13-09-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 THL1_RS10530 585a77ec22f838259ef1baa095357b32 404 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 256 289 - T 13-09-2016 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 UniPathway: UPA00344 THL1_RS10530 585a77ec22f838259ef1baa095357b32 404 Pfam PF03454 MoeA C-terminal region (domain IV) 334 399 5.5E-15 T 13-09-2016 IPR005111 MoeA, C-terminal, domain IV GO:0032324 MetaCyc: PWY-6823|UniPathway: UPA00344 THL1_RS10530 585a77ec22f838259ef1baa095357b32 404 SUPERFAMILY SSF53218 181 324 1.96E-40 T 13-09-2016 IPR001453 MoaB/Mog domain THL1_RS10530 585a77ec22f838259ef1baa095357b32 404 PANTHER PTHR10192 1 402 6.0E-186 T 13-09-2016 THL1_RS10530 585a77ec22f838259ef1baa095357b32 404 Gene3D G3DSA:3.90.105.10 135 166 1.1E-19 T 13-09-2016 THL1_RS10530 585a77ec22f838259ef1baa095357b32 404 Pfam PF00994 Probable molybdopterin binding domain 184 318 1.3E-25 T 13-09-2016 IPR001453 MoaB/Mog domain THL1_RS11590 f931d395e8848b2b8d19cb1e6ef63cc3 130 PANTHER PTHR10173:SF18 6 129 1.6E-58 T 13-09-2016 THL1_RS11590 f931d395e8848b2b8d19cb1e6ef63cc3 130 SUPERFAMILY SSF51316 6 129 9.42E-56 T 13-09-2016 IPR011057 Mss4-like THL1_RS11590 f931d395e8848b2b8d19cb1e6ef63cc3 130 Pfam PF01641 SelR domain 11 129 4.3E-52 T 13-09-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 THL1_RS11590 f931d395e8848b2b8d19cb1e6ef63cc3 130 Gene3D G3DSA:2.170.150.20 4 129 2.3E-58 T 13-09-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 THL1_RS11590 f931d395e8848b2b8d19cb1e6ef63cc3 130 PANTHER PTHR10173 6 129 1.6E-58 T 13-09-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 THL1_RS11590 f931d395e8848b2b8d19cb1e6ef63cc3 130 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 2 130 36.817 T 13-09-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 THL1_RS11590 f931d395e8848b2b8d19cb1e6ef63cc3 130 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 9 128 4.2E-53 T 13-09-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 THL1_RS13895 bd203048da0c6d180a22dcdf857978de 434 SUPERFAMILY SSF103473 16 419 5.49E-70 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS13895 bd203048da0c6d180a22dcdf857978de 434 PANTHER PTHR23505 17 433 3.4E-51 T 13-09-2016 THL1_RS13895 bd203048da0c6d180a22dcdf857978de 434 Gene3D G3DSA:1.20.1250.20 20 204 5.0E-34 T 13-09-2016 THL1_RS13895 bd203048da0c6d180a22dcdf857978de 434 Gene3D G3DSA:1.20.1250.20 221 421 1.0E-21 T 13-09-2016 THL1_RS13895 bd203048da0c6d180a22dcdf857978de 434 Pfam PF07690 Major Facilitator Superfamily 33 375 1.6E-42 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS13975 6b007779fef7948e02e2c834a7e64df7 265 SUPERFAMILY SSF53474 17 265 4.05E-42 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS13975 6b007779fef7948e02e2c834a7e64df7 265 Gene3D G3DSA:3.40.50.1820 18 264 2.8E-40 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS13975 6b007779fef7948e02e2c834a7e64df7 265 Pfam PF12697 Alpha/beta hydrolase family 39 258 2.0E-16 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS13975 6b007779fef7948e02e2c834a7e64df7 265 PANTHER PTHR10992 19 265 1.3E-26 T 13-09-2016 THL1_RS03340 bc5645b1decbba4ca8c327355c7a61e4 112 Pfam PF01230 HIT domain 11 106 2.0E-26 T 13-09-2016 IPR001310 Histidine triad (HIT) protein THL1_RS03340 bc5645b1decbba4ca8c327355c7a61e4 112 SUPERFAMILY SSF54197 2 111 1.02E-41 T 13-09-2016 IPR011146 HIT-like domain GO:0003824 THL1_RS03340 bc5645b1decbba4ca8c327355c7a61e4 112 Gene3D G3DSA:3.30.428.10 2 112 8.1E-45 T 13-09-2016 IPR011146 HIT-like domain GO:0003824 THL1_RS03340 bc5645b1decbba4ca8c327355c7a61e4 112 ProSitePatterns PS00892 HIT domain signature. 85 103 - T 13-09-2016 IPR019808 Histidine triad, conserved site THL1_RS03340 bc5645b1decbba4ca8c327355c7a61e4 112 PRINTS PR00332 Histidine triad family signature 92 102 2.5E-19 T 13-09-2016 IPR001310 Histidine triad (HIT) protein THL1_RS03340 bc5645b1decbba4ca8c327355c7a61e4 112 PRINTS PR00332 Histidine triad family signature 25 43 2.5E-19 T 13-09-2016 IPR001310 Histidine triad (HIT) protein THL1_RS03340 bc5645b1decbba4ca8c327355c7a61e4 112 PRINTS PR00332 Histidine triad family signature 4 20 2.5E-19 T 13-09-2016 IPR001310 Histidine triad (HIT) protein THL1_RS03340 bc5645b1decbba4ca8c327355c7a61e4 112 PANTHER PTHR23089 2 112 1.6E-50 T 13-09-2016 IPR001310 Histidine triad (HIT) protein THL1_RS18685 ea6999d5a0d9cd6db87b621967fe642e 230 Gene3D G3DSA:3.40.50.1000 75 216 2.9E-42 T 13-09-2016 IPR023214 HAD-like domain THL1_RS18685 ea6999d5a0d9cd6db87b621967fe642e 230 Gene3D G3DSA:1.10.150.240 22 74 6.1E-13 T 13-09-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 THL1_RS18685 ea6999d5a0d9cd6db87b621967fe642e 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 186 2.1E-32 T 13-09-2016 IPR023214 HAD-like domain THL1_RS18685 ea6999d5a0d9cd6db87b621967fe642e 230 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 96 180 4.5E-11 T 13-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THL1_RS18685 ea6999d5a0d9cd6db87b621967fe642e 230 PANTHER PTHR18901 3 220 5.5E-80 T 13-09-2016 THL1_RS18685 ea6999d5a0d9cd6db87b621967fe642e 230 PANTHER PTHR18901:SF40 3 220 5.5E-80 T 13-09-2016 THL1_RS18685 ea6999d5a0d9cd6db87b621967fe642e 230 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 65 186 1.8E-9 T 13-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THL1_RS18685 ea6999d5a0d9cd6db87b621967fe642e 230 SUPERFAMILY SSF56784 3 217 6.94E-59 T 13-09-2016 IPR023214 HAD-like domain THL1_RS00225 95519ea754c56f57dc06a560d2eee129 682 Gene3D G3DSA:3.40.390.10 360 505 1.0E-56 T 13-09-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 THL1_RS00225 95519ea754c56f57dc06a560d2eee129 682 PANTHER PTHR11804:SF8 4 679 0.0 T 13-09-2016 THL1_RS00225 95519ea754c56f57dc06a560d2eee129 682 SUPERFAMILY SSF55486 3 676 9.16E-206 T 13-09-2016 THL1_RS00225 95519ea754c56f57dc06a560d2eee129 682 Pfam PF01432 Peptidase family M3 225 676 5.6E-147 T 13-09-2016 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 THL1_RS00225 95519ea754c56f57dc06a560d2eee129 682 PANTHER PTHR11804 4 679 0.0 T 13-09-2016 THL1_RS00225 95519ea754c56f57dc06a560d2eee129 682 Gene3D G3DSA:1.20.1050.40 12 141 8.3E-26 T 13-09-2016 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal THL1_RS00225 95519ea754c56f57dc06a560d2eee129 682 Gene3D G3DSA:1.10.1370.10 143 351 6.2E-137 T 13-09-2016 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 THL1_RS00225 95519ea754c56f57dc06a560d2eee129 682 Gene3D G3DSA:1.10.1370.10 506 677 6.2E-137 T 13-09-2016 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 THL1_RS17520 b10ca983334100492025050ac4147afc 202 SUPERFAMILY SSF48498 77 188 1.22E-12 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS17520 b10ca983334100492025050ac4147afc 202 SUPERFAMILY SSF46689 3 69 6.14E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17520 b10ca983334100492025050ac4147afc 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 3.9E-8 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS17520 b10ca983334100492025050ac4147afc 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 3.9E-8 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS17520 b10ca983334100492025050ac4147afc 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 2.1E-15 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS17520 b10ca983334100492025050ac4147afc 202 Gene3D G3DSA:1.10.10.60 4 55 2.4E-18 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17520 b10ca983334100492025050ac4147afc 202 PANTHER PTHR30055 9 175 1.4E-23 T 13-09-2016 THL1_RS17520 b10ca983334100492025050ac4147afc 202 Gene3D G3DSA:1.10.357.10 56 189 1.1E-22 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS17130 784d2724f1544bd367c0b333d21b3936 223 Gene3D G3DSA:1.10.760.10 55 123 5.7E-22 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS17130 784d2724f1544bd367c0b333d21b3936 223 PANTHER PTHR33751 54 223 1.3E-34 T 13-09-2016 THL1_RS17130 784d2724f1544bd367c0b333d21b3936 223 Pfam PF00034 Cytochrome c 139 217 4.0E-9 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS17130 784d2724f1544bd367c0b333d21b3936 223 SUPERFAMILY SSF46626 129 220 3.3E-20 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS17130 784d2724f1544bd367c0b333d21b3936 223 Gene3D G3DSA:1.10.760.10 130 217 3.9E-22 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS17130 784d2724f1544bd367c0b333d21b3936 223 PANTHER PTHR33751:SF3 54 223 1.3E-34 T 13-09-2016 THL1_RS17130 784d2724f1544bd367c0b333d21b3936 223 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 55 119 1.9E-5 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS17130 784d2724f1544bd367c0b333d21b3936 223 SUPERFAMILY SSF46626 56 124 3.51E-18 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS12345 e8e1abf114f0acc2c3f39e39d5a3ca76 206 Hamap MF_00695 High frequency lysogenization protein HflD [hflD]. 1 205 33.92 T 13-09-2016 IPR007451 Uncharacterised protein family UPF0274 THL1_RS12345 e8e1abf114f0acc2c3f39e39d5a3ca76 206 ProDom PD037115 UPF0274 YCFC HI0638 METABOLISM UNCHARACTERIZED VV1342 PURINE INVOLVED SO2634 HFLD 9 196 9.0E-89 T 13-09-2016 IPR007451 Uncharacterised protein family UPF0274 THL1_RS12345 e8e1abf114f0acc2c3f39e39d5a3ca76 206 Pfam PF04356 Protein of unknown function (DUF489) 6 197 3.6E-70 T 13-09-2016 IPR007451 Uncharacterised protein family UPF0274 THL1_RS12345 e8e1abf114f0acc2c3f39e39d5a3ca76 206 PANTHER PTHR38100:SF1 1 206 1.1E-87 T 13-09-2016 THL1_RS12345 e8e1abf114f0acc2c3f39e39d5a3ca76 206 PANTHER PTHR38100 1 206 1.1E-87 T 13-09-2016 THL1_RS12345 e8e1abf114f0acc2c3f39e39d5a3ca76 206 Gene3D G3DSA:1.10.3890.10 1 204 3.3E-77 T 13-09-2016 IPR007451 Uncharacterised protein family UPF0274 THL1_RS12345 e8e1abf114f0acc2c3f39e39d5a3ca76 206 SUPERFAMILY SSF101322 1 205 2.22E-73 T 13-09-2016 IPR007451 Uncharacterised protein family UPF0274 THL1_RS02085 80a64f5a2d37badacebff5560ff58588 228 Gene3D G3DSA:3.40.50.2300 2 122 1.5E-34 T 13-09-2016 THL1_RS02085 80a64f5a2d37badacebff5560ff58588 228 Pfam PF00072 Response regulator receiver domain 4 112 4.4E-24 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02085 80a64f5a2d37badacebff5560ff58588 228 PANTHER PTHR26402:SF573 2 222 8.9E-128 T 13-09-2016 THL1_RS02085 80a64f5a2d37badacebff5560ff58588 228 SMART SM00448 2 112 5.7E-37 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02085 80a64f5a2d37badacebff5560ff58588 228 PANTHER PTHR26402 2 222 8.9E-128 T 13-09-2016 THL1_RS02085 80a64f5a2d37badacebff5560ff58588 228 SUPERFAMILY SSF46894 134 223 6.8E-20 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS02085 80a64f5a2d37badacebff5560ff58588 228 SUPERFAMILY SSF52172 1 125 1.57E-36 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS02085 80a64f5a2d37badacebff5560ff58588 228 Gene3D G3DSA:1.10.10.10 132 224 6.4E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02085 80a64f5a2d37badacebff5560ff58588 228 SMART SM00862 147 223 2.7E-20 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS02085 80a64f5a2d37badacebff5560ff58588 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 222 2.0E-19 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS01570 c833dc11a62aee6db6b763885d55ec69 491 SUPERFAMILY SSF54373 296 399 6.28E-13 T 13-09-2016 THL1_RS01570 c833dc11a62aee6db6b763885d55ec69 491 Pfam PF01593 Flavin containing amine oxidoreductase 36 451 2.7E-51 T 13-09-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 THL1_RS01570 c833dc11a62aee6db6b763885d55ec69 491 Gene3D G3DSA:3.50.50.60 217 313 8.7E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01570 c833dc11a62aee6db6b763885d55ec69 491 Gene3D G3DSA:3.50.50.60 23 99 8.7E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01570 c833dc11a62aee6db6b763885d55ec69 491 Gene3D G3DSA:3.50.50.60 410 456 8.7E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01570 c833dc11a62aee6db6b763885d55ec69 491 Gene3D G3DSA:1.10.405.10 124 204 3.1E-6 T 13-09-2016 THL1_RS01570 c833dc11a62aee6db6b763885d55ec69 491 PANTHER PTHR10742:SF255 22 475 5.6E-105 T 13-09-2016 THL1_RS01570 c833dc11a62aee6db6b763885d55ec69 491 SUPERFAMILY SSF51905 411 452 3.56E-56 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01570 c833dc11a62aee6db6b763885d55ec69 491 SUPERFAMILY SSF51905 25 315 3.56E-56 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01570 c833dc11a62aee6db6b763885d55ec69 491 PANTHER PTHR10742 22 475 5.6E-105 T 13-09-2016 THL1_RS01570 c833dc11a62aee6db6b763885d55ec69 491 PRINTS PR00757 Flavin-containing amine oxidase signature 432 449 2.2E-11 T 13-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 THL1_RS01570 c833dc11a62aee6db6b763885d55ec69 491 PRINTS PR00757 Flavin-containing amine oxidase signature 300 319 2.2E-11 T 13-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 THL1_RS01570 c833dc11a62aee6db6b763885d55ec69 491 PRINTS PR00757 Flavin-containing amine oxidase signature 28 47 2.2E-11 T 13-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 THL1_RS01570 c833dc11a62aee6db6b763885d55ec69 491 PRINTS PR00757 Flavin-containing amine oxidase signature 401 423 2.2E-11 T 13-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 THL1_RS27880 dffab650dba1da8075fe1f0a57444b56 206 PANTHER PTHR23117 1 197 7.0E-93 T 13-09-2016 THL1_RS27880 dffab650dba1da8075fe1f0a57444b56 206 Gene3D G3DSA:3.40.50.300 1 21 3.2E-48 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27880 dffab650dba1da8075fe1f0a57444b56 206 Gene3D G3DSA:3.40.50.300 88 200 3.2E-48 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27880 dffab650dba1da8075fe1f0a57444b56 206 SUPERFAMILY SSF52540 4 189 5.3E-69 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27880 dffab650dba1da8075fe1f0a57444b56 206 Hamap MF_00328 Guanylate kinase [gmk]. 4 187 36.304 T 13-09-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 THL1_RS27880 dffab650dba1da8075fe1f0a57444b56 206 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 6 184 1.2E-74 T 13-09-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 THL1_RS27880 dffab650dba1da8075fe1f0a57444b56 206 PANTHER PTHR23117:SF13 1 197 7.0E-93 T 13-09-2016 THL1_RS27880 dffab650dba1da8075fe1f0a57444b56 206 SMART SM00072 5 187 1.1E-61 T 13-09-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit THL1_RS27880 dffab650dba1da8075fe1f0a57444b56 206 Gene3D G3DSA:3.40.50.300 22 43 4.1E-4 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27880 dffab650dba1da8075fe1f0a57444b56 206 Gene3D G3DSA:3.30.63.10 44 87 5.2E-27 T 13-09-2016 THL1_RS27880 dffab650dba1da8075fe1f0a57444b56 206 Pfam PF00625 Guanylate kinase 7 185 1.2E-53 T 13-09-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit THL1_RS26775 ea3b7736d0f71a23fd8037861a1574bd 355 SUPERFAMILY SSF48150 3 225 3.14E-75 T 13-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 THL1_RS26775 ea3b7736d0f71a23fd8037861a1574bd 355 SUPERFAMILY SSF55811 220 345 7.75E-24 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS26775 ea3b7736d0f71a23fd8037861a1574bd 355 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 168 3.9E-19 T 13-09-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 THL1_RS26775 ea3b7736d0f71a23fd8037861a1574bd 355 Pfam PF14815 NUDIX domain 238 343 9.7E-21 T 13-09-2016 IPR029119 MutY, C-terminal THL1_RS26775 ea3b7736d0f71a23fd8037861a1574bd 355 Pfam PF00633 Helix-hairpin-helix motif 100 127 1.3E-7 T 13-09-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 THL1_RS26775 ea3b7736d0f71a23fd8037861a1574bd 355 Gene3D G3DSA:3.90.79.10 232 346 1.8E-21 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS26775 ea3b7736d0f71a23fd8037861a1574bd 355 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 5 277 2.4E-112 T 13-09-2016 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 THL1_RS26775 ea3b7736d0f71a23fd8037861a1574bd 355 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 13-09-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: REACT_216 THL1_RS26775 ea3b7736d0f71a23fd8037861a1574bd 355 Gene3D G3DSA:1.10.1670.10 123 223 1.0E-38 T 13-09-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal THL1_RS26775 ea3b7736d0f71a23fd8037861a1574bd 355 SMART SM00478 39 190 4.2E-46 T 13-09-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 THL1_RS26775 ea3b7736d0f71a23fd8037861a1574bd 355 PANTHER PTHR10359 4 342 1.4E-102 T 13-09-2016 THL1_RS26775 ea3b7736d0f71a23fd8037861a1574bd 355 Gene3D G3DSA:1.10.340.30 22 122 6.3E-44 T 13-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 THL1_RS18680 72696aa451bf753a2ba0f14fe80e5fe5 326 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 75 277 2.1E-47 T 13-09-2016 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 THL1_RS18680 72696aa451bf753a2ba0f14fe80e5fe5 326 Gene3D G3DSA:3.90.226.10 47 176 4.3E-50 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS18680 72696aa451bf753a2ba0f14fe80e5fe5 326 Gene3D G3DSA:3.90.226.10 214 301 4.3E-50 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS18680 72696aa451bf753a2ba0f14fe80e5fe5 326 PANTHER PTHR30341 2 323 1.5E-141 T 13-09-2016 THL1_RS18680 72696aa451bf753a2ba0f14fe80e5fe5 326 PANTHER PTHR30341:SF1 2 323 1.5E-141 T 13-09-2016 THL1_RS18680 72696aa451bf753a2ba0f14fe80e5fe5 326 Pfam PF01343 Peptidase family S49 138 281 4.0E-34 T 13-09-2016 IPR002142 Peptidase S49 GO:0006508|GO:0008233 THL1_RS18680 72696aa451bf753a2ba0f14fe80e5fe5 326 SUPERFAMILY SSF52096 56 184 5.42E-43 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS18680 72696aa451bf753a2ba0f14fe80e5fe5 326 SUPERFAMILY SSF52096 213 275 5.42E-43 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS22595 a4e9ca3b3bad91aa65825a7921102592 167 SMART SM00935 10 164 6.8E-36 T 13-09-2016 IPR005632 Chaperone protein Skp GO:0051082 THL1_RS22595 a4e9ca3b3bad91aa65825a7921102592 167 Gene3D G3DSA:3.30.910.20 12 58 1.0E-15 T 13-09-2016 THL1_RS22595 a4e9ca3b3bad91aa65825a7921102592 167 Gene3D G3DSA:3.30.910.20 96 164 1.0E-15 T 13-09-2016 THL1_RS22595 a4e9ca3b3bad91aa65825a7921102592 167 PANTHER PTHR35089:SF1 2 167 9.5E-43 T 13-09-2016 THL1_RS22595 a4e9ca3b3bad91aa65825a7921102592 167 SUPERFAMILY SSF111384 21 164 3.27E-29 T 13-09-2016 IPR024930 Skp domain THL1_RS22595 a4e9ca3b3bad91aa65825a7921102592 167 PANTHER PTHR35089 2 167 9.5E-43 T 13-09-2016 THL1_RS22595 a4e9ca3b3bad91aa65825a7921102592 167 Pfam PF03938 Outer membrane protein (OmpH-like) 8 163 6.4E-23 T 13-09-2016 IPR005632 Chaperone protein Skp GO:0051082 THL1_RS13635 e557f66a1777f9b10ef1d3a9bdae9749 236 PANTHER PTHR21600:SF21 1 236 3.1E-88 T 13-09-2016 THL1_RS13635 e557f66a1777f9b10ef1d3a9bdae9749 236 Gene3D G3DSA:3.10.290.10 3 66 5.6E-17 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS13635 e557f66a1777f9b10ef1d3a9bdae9749 236 SUPERFAMILY SSF55174 5 59 2.36E-10 T 13-09-2016 THL1_RS13635 e557f66a1777f9b10ef1d3a9bdae9749 236 PANTHER PTHR21600 1 236 3.1E-88 T 13-09-2016 THL1_RS13635 e557f66a1777f9b10ef1d3a9bdae9749 236 SUPERFAMILY SSF55120 101 234 4.8E-18 T 13-09-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS22970 c42dd8dd2cbde5587086159cf62a0efd 268 SUPERFAMILY SSF161098 6 261 3.01E-49 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS22970 c42dd8dd2cbde5587086159cf62a0efd 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 254 9.3E-16 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS22970 c42dd8dd2cbde5587086159cf62a0efd 268 PANTHER PTHR30193:SF20 1 268 8.7E-74 T 13-09-2016 THL1_RS22970 c42dd8dd2cbde5587086159cf62a0efd 268 PANTHER PTHR30193 1 268 8.7E-74 T 13-09-2016 THL1_RS22970 c42dd8dd2cbde5587086159cf62a0efd 268 Gene3D G3DSA:1.10.3720.10 12 259 9.8E-48 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS12290 013c8c74e05ee7d9aa3c40e2302419cc 593 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 99 154 5.0E-25 T 13-09-2016 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 THL1_RS12290 013c8c74e05ee7d9aa3c40e2302419cc 593 PANTHER PTHR11993:SF28 141 588 1.0E-300 T 13-09-2016 THL1_RS12290 013c8c74e05ee7d9aa3c40e2302419cc 593 Gene3D G3DSA:1.10.645.10 209 577 8.8E-50 T 13-09-2016 IPR029014 NiFe hydrogenase-like THL1_RS12290 013c8c74e05ee7d9aa3c40e2302419cc 593 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 323 593 2.0E-106 T 13-09-2016 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 THL1_RS12290 013c8c74e05ee7d9aa3c40e2302419cc 593 SUPERFAMILY SSF143243 18 223 1.31E-60 T 13-09-2016 THL1_RS12290 013c8c74e05ee7d9aa3c40e2302419cc 593 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 209 593 8.6E-172 T 13-09-2016 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 THL1_RS12290 013c8c74e05ee7d9aa3c40e2302419cc 593 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 20 179 25.822 T 13-09-2016 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 THL1_RS12290 013c8c74e05ee7d9aa3c40e2302419cc 593 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 43 170 2.2E-43 T 13-09-2016 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 THL1_RS12290 013c8c74e05ee7d9aa3c40e2302419cc 593 SUPERFAMILY SSF56762 219 593 1.96E-124 T 13-09-2016 IPR029014 NiFe hydrogenase-like THL1_RS12290 013c8c74e05ee7d9aa3c40e2302419cc 593 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 44 172 2.3E-41 T 13-09-2016 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 THL1_RS12290 013c8c74e05ee7d9aa3c40e2302419cc 593 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 246 257 - T 13-09-2016 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 THL1_RS12290 013c8c74e05ee7d9aa3c40e2302419cc 593 Hamap MF_01359 NADH-quinone oxidoreductase subunit C/D [nuoC]. 10 593 71.361 T 13-09-2016 IPR023062 NADH dehydrogenase, subunit CD GO:0030964|GO:0050136|GO:0055114 KEGG: 00190+1.6.5.11 THL1_RS12290 013c8c74e05ee7d9aa3c40e2302419cc 593 PANTHER PTHR11993 141 588 1.0E-300 T 13-09-2016 THL1_RS12290 013c8c74e05ee7d9aa3c40e2302419cc 593 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 205 593 42.659 T 13-09-2016 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 THL1_RS22600 dc3e5b1b8202b4261d27a8040424bfbb 787 PANTHER PTHR12815 3 663 7.7E-262 T 13-09-2016 THL1_RS22600 dc3e5b1b8202b4261d27a8040424bfbb 787 PANTHER PTHR12815 684 787 7.7E-262 T 13-09-2016 THL1_RS22600 dc3e5b1b8202b4261d27a8040424bfbb 787 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 1 787 25.454 T 13-09-2016 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 THL1_RS22600 dc3e5b1b8202b4261d27a8040424bfbb 787 PIRSF PIRSF006076 1 787 1.2E-263 T 13-09-2016 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 THL1_RS22600 dc3e5b1b8202b4261d27a8040424bfbb 787 Pfam PF01103 Surface antigen 447 787 1.6E-93 T 13-09-2016 IPR000184 Bacterial surface antigen (D15) GO:0019867 THL1_RS22600 dc3e5b1b8202b4261d27a8040424bfbb 787 PANTHER PTHR12815:SF11 684 787 7.7E-262 T 13-09-2016 THL1_RS22600 dc3e5b1b8202b4261d27a8040424bfbb 787 PANTHER PTHR12815:SF11 3 663 7.7E-262 T 13-09-2016 THL1_RS22600 dc3e5b1b8202b4261d27a8040424bfbb 787 Gene3D G3DSA:2.40.160.50 404 787 3.9E-23 T 13-09-2016 THL1_RS22600 dc3e5b1b8202b4261d27a8040424bfbb 787 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 23 787 2.1E-261 T 13-09-2016 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 THL1_RS22600 dc3e5b1b8202b4261d27a8040424bfbb 787 Pfam PF07244 Surface antigen variable number repeat 347 420 3.4E-15 T 13-09-2016 IPR010827 Surface antigen variable number GO:0019867 THL1_RS22600 dc3e5b1b8202b4261d27a8040424bfbb 787 Pfam PF07244 Surface antigen variable number repeat 175 262 8.3E-19 T 13-09-2016 IPR010827 Surface antigen variable number GO:0019867 THL1_RS22600 dc3e5b1b8202b4261d27a8040424bfbb 787 Pfam PF07244 Surface antigen variable number repeat 265 343 3.5E-14 T 13-09-2016 IPR010827 Surface antigen variable number GO:0019867 THL1_RS22600 dc3e5b1b8202b4261d27a8040424bfbb 787 Pfam PF07244 Surface antigen variable number repeat 92 171 2.8E-13 T 13-09-2016 IPR010827 Surface antigen variable number GO:0019867 THL1_RS22385 ed5af02a51c68bc2f2b4a884f88a64ae 213 PANTHER PTHR11260 6 205 2.5E-67 T 13-09-2016 THL1_RS22385 ed5af02a51c68bc2f2b4a884f88a64ae 213 Gene3D G3DSA:3.40.30.10 9 89 3.6E-24 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS22385 ed5af02a51c68bc2f2b4a884f88a64ae 213 Gene3D G3DSA:1.20.1050.10 90 192 6.4E-17 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS22385 ed5af02a51c68bc2f2b4a884f88a64ae 213 SUPERFAMILY SSF52833 7 89 2.62E-22 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS22385 ed5af02a51c68bc2f2b4a884f88a64ae 213 Pfam PF13410 Glutathione S-transferase, C-terminal domain 121 186 1.1E-6 T 13-09-2016 THL1_RS22385 ed5af02a51c68bc2f2b4a884f88a64ae 213 SUPERFAMILY SSF47616 87 201 5.54E-19 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS22385 ed5af02a51c68bc2f2b4a884f88a64ae 213 Pfam PF02798 Glutathione S-transferase, N-terminal domain 7 78 2.1E-12 T 13-09-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THL1_RS22385 ed5af02a51c68bc2f2b4a884f88a64ae 213 PANTHER PTHR11260:SF253 6 205 2.5E-67 T 13-09-2016 THL1_RS27615 208a06f61509c103cf54d59e9d5a99c0 438 Pfam PF14535 AMP-binding enzyme C-terminal domain 343 431 4.5E-12 T 13-09-2016 IPR028154 AMP-dependent ligase, C-terminal THL1_RS27615 208a06f61509c103cf54d59e9d5a99c0 438 PANTHER PTHR36932:SF1 53 384 4.6E-40 T 13-09-2016 THL1_RS27615 208a06f61509c103cf54d59e9d5a99c0 438 Gene3D G3DSA:3.30.300.30 333 430 9.1E-20 T 13-09-2016 THL1_RS27615 208a06f61509c103cf54d59e9d5a99c0 438 SUPERFAMILY SSF56801 47 389 1.83E-42 T 13-09-2016 THL1_RS27615 208a06f61509c103cf54d59e9d5a99c0 438 Gene3D G3DSA:3.40.50.980 87 252 5.2E-12 T 13-09-2016 THL1_RS27615 208a06f61509c103cf54d59e9d5a99c0 438 PANTHER PTHR36932 53 384 4.6E-40 T 13-09-2016 THL1_RS27615 208a06f61509c103cf54d59e9d5a99c0 438 Pfam PF00501 AMP-binding enzyme 76 293 4.9E-11 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS04935 5f5e0cad69a9c57a720472460f94deda 163 Pfam PF14341 PilX N-terminal 6 48 8.8E-11 T 13-09-2016 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain THL1_RS07145 ced652c2e1ecc34b23c3ec95aa63ec8b 257 PANTHER PTHR24322 14 138 4.2E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07145 ced652c2e1ecc34b23c3ec95aa63ec8b 257 PANTHER PTHR24322 154 184 4.2E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07145 ced652c2e1ecc34b23c3ec95aa63ec8b 257 SUPERFAMILY SSF51735 9 244 1.63E-76 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07145 ced652c2e1ecc34b23c3ec95aa63ec8b 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS07145 ced652c2e1ecc34b23c3ec95aa63ec8b 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 244 1.5E-58 T 13-09-2016 THL1_RS07145 ced652c2e1ecc34b23c3ec95aa63ec8b 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 189 0.0011 T 13-09-2016 THL1_RS07145 ced652c2e1ecc34b23c3ec95aa63ec8b 257 Gene3D G3DSA:3.40.50.720 5 244 9.0E-78 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07145 ced652c2e1ecc34b23c3ec95aa63ec8b 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.1E-13 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07145 ced652c2e1ecc34b23c3ec95aa63ec8b 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.1E-13 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07145 ced652c2e1ecc34b23c3ec95aa63ec8b 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.1E-13 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07145 ced652c2e1ecc34b23c3ec95aa63ec8b 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 5.3E-39 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07145 ced652c2e1ecc34b23c3ec95aa63ec8b 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 5.3E-39 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07145 ced652c2e1ecc34b23c3ec95aa63ec8b 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 5.3E-39 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07145 ced652c2e1ecc34b23c3ec95aa63ec8b 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 5.3E-39 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07145 ced652c2e1ecc34b23c3ec95aa63ec8b 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 5.3E-39 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07145 ced652c2e1ecc34b23c3ec95aa63ec8b 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 5.3E-39 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 Gene3D G3DSA:3.40.50.2300 974 1097 1.2E-14 T 13-09-2016 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 Gene3D G3DSA:3.40.50.2300 1112 1232 1.1E-40 T 13-09-2016 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 SUPERFAMILY SSF55874 660 836 3.54E-46 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 Gene3D G3DSA:3.40.50.2300 854 969 1.3E-21 T 13-09-2016 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 Pfam PF00072 Response regulator receiver domain 1116 1226 5.9E-28 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 Pfam PF00072 Response regulator receiver domain 859 965 1.5E-12 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 Pfam PF00072 Response regulator receiver domain 981 1071 4.2E-10 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 Pfam PF13188 PAS domain 467 530 2.5E-10 T 13-09-2016 IPR000014 PAS domain THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 SMART SM00388 603 671 3.8E-21 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 Gene3D G3DSA:3.30.565.10 671 841 4.6E-46 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 SUPERFAMILY SSF52172 855 969 6.12E-21 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 SMART SM01079 80 270 7.6E-68 T 13-09-2016 IPR006189 CHASE domain THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 719 834 7.5E-29 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 SUPERFAMILY SSF52172 1113 1231 1.99E-40 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 Pfam PF08448 PAS fold 361 444 5.0E-6 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 SMART SM00091 467 532 7.8E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 SMART SM00091 355 420 7.9E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 SUPERFAMILY SSF55785 479 591 4.83E-23 T 13-09-2016 IPR000014 PAS domain THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 351 468 3.5E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 464 590 7.5E-26 T 13-09-2016 IPR000014 PAS domain THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 Gene3D G3DSA:1.10.287.130 595 667 3.0E-16 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 Pfam PF03924 CHASE domain 83 263 1.8E-50 T 13-09-2016 IPR006189 CHASE domain THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 Gene3D G3DSA:3.30.450.20 349 458 1.9E-11 T 13-09-2016 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 SUPERFAMILY SSF52172 977 1062 8.4E-14 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 SMART SM00387 718 836 1.7E-39 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 PANTHER PTHR24423 465 850 1.3E-164 T 13-09-2016 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 PANTHER PTHR24423 1113 1232 1.3E-164 T 13-09-2016 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 PANTHER PTHR24423 13 57 1.3E-164 T 13-09-2016 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 PRINTS PR00344 Bacterial sensor protein C-terminal signature 761 775 1.4E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 PRINTS PR00344 Bacterial sensor protein C-terminal signature 796 814 1.4E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 PRINTS PR00344 Bacterial sensor protein C-terminal signature 820 833 1.4E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 PRINTS PR00344 Bacterial sensor protein C-terminal signature 779 789 1.4E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 SMART SM00448 1114 1226 1.7E-37 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 SMART SM00448 978 1092 1.5E-5 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 SMART SM00448 857 966 2.0E-10 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 SMART SM00086 543 583 8.8E-5 T 13-09-2016 IPR001610 PAC motif THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 Pfam PF00512 His Kinase A (phospho-acceptor) domain 604 671 8.8E-17 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 SUPERFAMILY SSF55785 349 452 3.24E-10 T 13-09-2016 IPR000014 PAS domain THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 Gene3D G3DSA:3.30.450.20 465 581 9.2E-21 T 13-09-2016 THL1_RS23690 0482eadbc37c89d671ffd45fd3c6ef0f 1242 SUPERFAMILY SSF47384 588 672 7.26E-21 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS15680 724f059b36d52495f1ec7637db7c292d 307 Gene3D G3DSA:1.10.10.10 48 100 5.4E-5 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS15680 724f059b36d52495f1ec7637db7c292d 307 TIGRFAM TIGR02277 PaaX_trns_reg: phenylacetic acid degradation operon negative regulatory protein PaaX 24 304 2.0E-100 T 13-09-2016 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 UniPathway: UPA00930 THL1_RS15680 724f059b36d52495f1ec7637db7c292d 307 Pfam PF08223 PaaX-like protein C-terminal domain 107 273 5.2E-60 T 13-09-2016 IPR013225 PaaX-like, C-terminal UniPathway: UPA00930 THL1_RS15680 724f059b36d52495f1ec7637db7c292d 307 PANTHER PTHR30319 5 306 6.3E-67 T 13-09-2016 THL1_RS15680 724f059b36d52495f1ec7637db7c292d 307 Pfam PF07848 PaaX-like protein 21 89 5.7E-31 T 13-09-2016 IPR012906 PaaX-like, N-terminal UniPathway: UPA00930 THL1_RS15680 724f059b36d52495f1ec7637db7c292d 307 PANTHER PTHR30319:SF1 5 306 6.3E-67 T 13-09-2016 THL1_RS15680 724f059b36d52495f1ec7637db7c292d 307 PIRSF PIRSF020623 1 307 6.6E-125 T 13-09-2016 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 UniPathway: UPA00930 THL1_RS15680 724f059b36d52495f1ec7637db7c292d 307 SUPERFAMILY SSF46785 46 131 8.53E-7 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00015 5d4d3223cdf76b1b0452801956f9e479 368 PANTHER PTHR32182 1 357 4.8E-60 T 13-09-2016 THL1_RS00015 5d4d3223cdf76b1b0452801956f9e479 368 Gene3D G3DSA:3.40.50.300 232 341 4.5E-34 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00015 5d4d3223cdf76b1b0452801956f9e479 368 Gene3D G3DSA:3.40.50.300 1 162 4.5E-34 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00015 5d4d3223cdf76b1b0452801956f9e479 368 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 359 1.5E-115 T 13-09-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 THL1_RS00015 5d4d3223cdf76b1b0452801956f9e479 368 ProSitePatterns PS00617 RecF protein signature 1. 118 138 - T 13-09-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 THL1_RS00015 5d4d3223cdf76b1b0452801956f9e479 368 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 368 93.439 T 13-09-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 THL1_RS00015 5d4d3223cdf76b1b0452801956f9e479 368 ProSitePatterns PS00618 RecF protein signature 2. 300 318 - T 13-09-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 THL1_RS00015 5d4d3223cdf76b1b0452801956f9e479 368 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 358 1.7E-36 T 13-09-2016 IPR003395 RecF/RecN/SMC, N-terminal THL1_RS00015 5d4d3223cdf76b1b0452801956f9e479 368 SUPERFAMILY SSF52540 1 341 2.37E-36 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00015 5d4d3223cdf76b1b0452801956f9e479 368 PANTHER PTHR32182:SF0 1 357 4.8E-60 T 13-09-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 THL1_RS05220 4373429177ade8e132d8978e19512340 336 PANTHER PTHR30465:SF0 1 169 5.1E-147 T 13-09-2016 THL1_RS05220 4373429177ade8e132d8978e19512340 336 Gene3D G3DSA:1.10.3720.10 89 163 6.8E-21 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS05220 4373429177ade8e132d8978e19512340 336 Gene3D G3DSA:1.10.3720.10 200 327 6.8E-21 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS05220 4373429177ade8e132d8978e19512340 336 PANTHER PTHR30465:SF0 190 334 5.1E-147 T 13-09-2016 THL1_RS05220 4373429177ade8e132d8978e19512340 336 PANTHER PTHR30465 190 334 5.1E-147 T 13-09-2016 THL1_RS05220 4373429177ade8e132d8978e19512340 336 SUPERFAMILY SSF161098 89 160 8.5E-21 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS05220 4373429177ade8e132d8978e19512340 336 SUPERFAMILY SSF161098 197 319 8.5E-21 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS05220 4373429177ade8e132d8978e19512340 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 333 3.1E-47 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS05220 4373429177ade8e132d8978e19512340 336 PANTHER PTHR30465 1 169 5.1E-147 T 13-09-2016 THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 SMART SM00316 135 202 1.5E-11 T 13-09-2016 IPR022967 RNA-binding domain, S1 THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 SUPERFAMILY SSF54814 202 280 7.19E-28 T 13-09-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 Gene3D G3DSA:2.40.50.140 131 200 1.8E-22 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 344 6.1E-122 T 13-09-2016 IPR010213 Transcription termination factor NusA GO:0003723 THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 SUPERFAMILY SSF69705 1 128 1.07E-38 T 13-09-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 Pfam PF00575 S1 RNA binding domain 136 197 1.4E-7 T 13-09-2016 IPR003029 S1 domain GO:0003676 THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 PANTHER PTHR22648:SF0 1 450 6.4E-177 T 13-09-2016 THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 367 415 1.4E-21 T 13-09-2016 IPR010214 Transcription termination factor NusA, C-terminal duplication THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 445 491 7.4E-18 T 13-09-2016 IPR010214 Transcription termination factor NusA, C-terminal duplication THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 Pfam PF13184 NusA-like KH domain 232 299 2.0E-26 T 13-09-2016 IPR025249 KH domain, NusA-like GO:0003723 THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 Gene3D G3DSA:1.10.150.20 359 422 5.2E-22 T 13-09-2016 THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 Gene3D G3DSA:1.10.150.20 431 492 3.3E-22 T 13-09-2016 THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 SUPERFAMILY SSF47794 357 418 1.29E-16 T 13-09-2016 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 PANTHER PTHR22648 1 450 6.4E-177 T 13-09-2016 THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 Gene3D G3DSA:3.30.300.20 201 279 9.9E-33 T 13-09-2016 IPR015946 K homology domain-like, alpha/beta THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 Pfam PF08529 NusA N-terminal domain 4 125 1.1E-36 T 13-09-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 Gene3D G3DSA:3.30.1480.10 1 126 7.1E-44 T 13-09-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 SUPERFAMILY SSF50249 134 201 4.21E-18 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 412 28.862 T 13-09-2016 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 Pfam PF14520 Helix-hairpin-helix domain 434 488 1.2E-7 T 13-09-2016 THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 Gene3D G3DSA:3.30.300.20 280 348 3.0E-27 T 13-09-2016 IPR015946 K homology domain-like, alpha/beta THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 SUPERFAMILY SSF54814 281 344 7.85E-15 T 13-09-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 THL1_RS24400 d5a3e119e4168f1e9967bdcf72cb9217 493 SUPERFAMILY SSF47794 432 492 2.04E-15 T 13-09-2016 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 THL1_RS28170 931cbe13ecc9f470c9dda7c7a1238b29 272 Gene3D G3DSA:1.10.260.40 4 58 4.9E-8 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS28170 931cbe13ecc9f470c9dda7c7a1238b29 272 SUPERFAMILY SSF47413 8 62 1.55E-7 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS28170 931cbe13ecc9f470c9dda7c7a1238b29 272 Pfam PF01381 Helix-turn-helix 17 58 2.7E-6 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS28170 931cbe13ecc9f470c9dda7c7a1238b29 272 SMART SM00530 8 62 4.8E-5 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS07925 facf611052e523dea06a10feca3541ab 218 PANTHER PTHR30614 1 218 4.6E-151 T 13-09-2016 THL1_RS07925 facf611052e523dea06a10feca3541ab 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 1.0E-28 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS07925 facf611052e523dea06a10feca3541ab 218 PANTHER PTHR30614:SF13 1 218 4.6E-151 T 13-09-2016 THL1_RS07925 facf611052e523dea06a10feca3541ab 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 216 6.3E-19 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07925 facf611052e523dea06a10feca3541ab 218 Gene3D G3DSA:1.10.3720.10 13 216 3.0E-45 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07925 facf611052e523dea06a10feca3541ab 218 SUPERFAMILY SSF161098 13 204 2.62E-42 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS23760 b4f946cca12dcfc09b1c6bf473dfb43c 286 Gene3D G3DSA:3.90.190.10 29 207 2.1E-20 T 13-09-2016 IPR029021 Protein-tyrosine phosphatase-like THL1_RS23760 b4f946cca12dcfc09b1c6bf473dfb43c 286 PANTHER PTHR31126 138 279 2.4E-56 T 13-09-2016 THL1_RS23760 b4f946cca12dcfc09b1c6bf473dfb43c 286 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 168 178 - T 13-09-2016 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311|GO:0016791 THL1_RS23760 b4f946cca12dcfc09b1c6bf473dfb43c 286 PANTHER PTHR31126 24 108 2.4E-56 T 13-09-2016 THL1_RS23760 b4f946cca12dcfc09b1c6bf473dfb43c 286 Pfam PF13350 Tyrosine phosphatase family 27 279 3.7E-69 T 13-09-2016 IPR026893 Tyrosine/serine-protein phosphatase IphP-type THL1_RS23760 b4f946cca12dcfc09b1c6bf473dfb43c 286 SUPERFAMILY SSF52799 27 278 5.05E-52 T 13-09-2016 IPR029021 Protein-tyrosine phosphatase-like THL1_RS23760 b4f946cca12dcfc09b1c6bf473dfb43c 286 PANTHER PTHR31126:SF21 138 279 2.4E-56 T 13-09-2016 THL1_RS23760 b4f946cca12dcfc09b1c6bf473dfb43c 286 PANTHER PTHR31126:SF21 24 108 2.4E-56 T 13-09-2016 THL1_RS22230 b289f60f00332dec433401e9561df019 201 Gene3D G3DSA:3.40.50.360 3 197 1.5E-68 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS22230 b289f60f00332dec433401e9561df019 201 SUPERFAMILY SSF52218 4 196 2.1E-62 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS22230 b289f60f00332dec433401e9561df019 201 PANTHER PTHR30546 3 196 1.1E-72 T 13-09-2016 THL1_RS22230 b289f60f00332dec433401e9561df019 201 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 6 196 2.3E-44 T 13-09-2016 IPR010089 Flavoprotein WrbA GO:0010181|GO:0045892 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 THL1_RS22230 b289f60f00332dec433401e9561df019 201 ProSitePatterns PS00201 Flavodoxin signature. 8 24 - T 13-09-2016 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 THL1_RS22230 b289f60f00332dec433401e9561df019 201 Hamap MF_01017 NAD(P)H dehydrogenase (quinone). 3 198 31.713 T 13-09-2016 IPR010089 Flavoprotein WrbA GO:0010181|GO:0045892 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 THL1_RS22230 b289f60f00332dec433401e9561df019 201 Pfam PF03358 NADPH-dependent FMN reductase 14 127 1.7E-8 T 13-09-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 THL1_RS12635 afaeb9556b3c9fe2691c95ded70fd944 258 SUPERFAMILY SSF55781 80 250 2.35E-35 T 13-09-2016 IPR029016 GAF domain-like THL1_RS12635 afaeb9556b3c9fe2691c95ded70fd944 258 SMART SM00346 6 92 2.9E-17 T 13-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 THL1_RS12635 afaeb9556b3c9fe2691c95ded70fd944 258 Gene3D G3DSA:3.30.450.40 81 250 1.7E-43 T 13-09-2016 IPR029016 GAF domain-like THL1_RS12635 afaeb9556b3c9fe2691c95ded70fd944 258 PANTHER PTHR30136:SF13 6 249 2.5E-82 T 13-09-2016 THL1_RS12635 afaeb9556b3c9fe2691c95ded70fd944 258 Pfam PF09339 IclR helix-turn-helix domain 6 55 5.3E-15 T 13-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 THL1_RS12635 afaeb9556b3c9fe2691c95ded70fd944 258 Gene3D G3DSA:1.10.10.10 5 76 6.3E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12635 afaeb9556b3c9fe2691c95ded70fd944 258 Pfam PF01614 Bacterial transcriptional regulator 123 249 8.3E-19 T 13-09-2016 IPR014757 Transcription regulator IclR, C-terminal THL1_RS12635 afaeb9556b3c9fe2691c95ded70fd944 258 SUPERFAMILY SSF46785 6 76 2.21E-14 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12635 afaeb9556b3c9fe2691c95ded70fd944 258 PANTHER PTHR30136 6 249 2.5E-82 T 13-09-2016 THL1_RS05725 26824ade3b4da688cf5750d7183226e6 320 SUPERFAMILY SSF55073 158 311 2.67E-14 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS05725 26824ade3b4da688cf5750d7183226e6 320 Gene3D G3DSA:3.30.70.270 155 311 2.0E-16 T 13-09-2016 THL1_RS05725 26824ade3b4da688cf5750d7183226e6 320 SUPERFAMILY SSF52172 5 148 1.57E-27 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS05725 26824ade3b4da688cf5750d7183226e6 320 PANTHER PTHR26402 6 155 2.7E-24 T 13-09-2016 THL1_RS05725 26824ade3b4da688cf5750d7183226e6 320 SMART SM00448 6 122 6.3E-24 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS05725 26824ade3b4da688cf5750d7183226e6 320 Gene3D G3DSA:3.40.50.2300 6 133 1.8E-25 T 13-09-2016 THL1_RS05725 26824ade3b4da688cf5750d7183226e6 320 Pfam PF00072 Response regulator receiver domain 8 121 1.1E-20 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS05725 26824ade3b4da688cf5750d7183226e6 320 Pfam PF00990 Diguanylate cyclase, GGDEF domain 155 311 4.5E-15 T 13-09-2016 IPR000160 GGDEF domain THL1_RS05725 26824ade3b4da688cf5750d7183226e6 320 SMART SM00267 142 317 3.2E-6 T 13-09-2016 IPR000160 GGDEF domain THL1_RS05725 26824ade3b4da688cf5750d7183226e6 320 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 149 312 5.5E-12 T 13-09-2016 IPR000160 GGDEF domain THL1_RS00785 d538050bed941b5dfb45701518d127fa 260 Pfam PF06833 Malonate decarboxylase gamma subunit (MdcE) 6 260 7.3E-93 T 13-09-2016 IPR011763 Acetyl-coenzyme A carboxyltransferase, C-terminal GO:0016874 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS00785 d538050bed941b5dfb45701518d127fa 260 SUPERFAMILY SSF52096 19 229 4.62E-18 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS00785 d538050bed941b5dfb45701518d127fa 260 Gene3D G3DSA:3.90.226.10 82 184 1.8E-13 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS00785 d538050bed941b5dfb45701518d127fa 260 TIGRFAM TIGR03134 malonate_gamma: biotin-independent malonate decarboxylase, gamma subunit 4 260 8.3E-96 T 13-09-2016 IPR009648 Biotin-dependent malonate decarboxylase, gamma subunit GO:0044262 MetaCyc: PWY-6060 THL1_RS11185 6523805d4cd87ea212c7e4753100462e 297 PANTHER PTHR30126:SF16 8 295 4.2E-131 T 13-09-2016 THL1_RS11185 6523805d4cd87ea212c7e4753100462e 297 SUPERFAMILY SSF53850 102 296 2.44E-29 T 13-09-2016 THL1_RS11185 6523805d4cd87ea212c7e4753100462e 297 SUPERFAMILY SSF46785 9 94 4.9E-15 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11185 6523805d4cd87ea212c7e4753100462e 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 69 1.6E-12 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS11185 6523805d4cd87ea212c7e4753100462e 297 Gene3D G3DSA:1.10.10.10 8 88 3.5E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11185 6523805d4cd87ea212c7e4753100462e 297 PANTHER PTHR30126 8 295 4.2E-131 T 13-09-2016 THL1_RS11185 6523805d4cd87ea212c7e4753100462e 297 Gene3D G3DSA:3.40.190.10 110 195 5.9E-14 T 13-09-2016 THL1_RS11185 6523805d4cd87ea212c7e4753100462e 297 Pfam PF03466 LysR substrate binding domain 102 294 2.6E-29 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS22195 671e185029f92d956c4b098165e926a5 91 Gene3D G3DSA:3.30.70.100 5 89 2.0E-28 T 13-09-2016 THL1_RS22195 671e185029f92d956c4b098165e926a5 91 PANTHER PTHR10029 9 91 2.3E-25 T 13-09-2016 THL1_RS22195 671e185029f92d956c4b098165e926a5 91 Pfam PF00708 Acylphosphatase 5 87 2.4E-24 T 13-09-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THL1_RS22195 671e185029f92d956c4b098165e926a5 91 SUPERFAMILY SSF54975 3 90 2.4E-26 T 13-09-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THL1_RS22195 671e185029f92d956c4b098165e926a5 91 ProSitePatterns PS00151 Acylphosphatase signature 2. 34 50 - T 13-09-2016 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THL1_RS19160 1e18c81b380f609e1aa5e5df9c9a0baa 255 PANTHER PTHR24321:SF6 1 253 2.8E-54 T 13-09-2016 THL1_RS19160 1e18c81b380f609e1aa5e5df9c9a0baa 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 249 1.7E-62 T 13-09-2016 THL1_RS19160 1e18c81b380f609e1aa5e5df9c9a0baa 255 Gene3D G3DSA:3.40.50.720 2 250 1.6E-85 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS19160 1e18c81b380f609e1aa5e5df9c9a0baa 255 SUPERFAMILY SSF51735 4 249 7.55E-83 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS19160 1e18c81b380f609e1aa5e5df9c9a0baa 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS19160 1e18c81b380f609e1aa5e5df9c9a0baa 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 185 3.6E-5 T 13-09-2016 THL1_RS19160 1e18c81b380f609e1aa5e5df9c9a0baa 255 PANTHER PTHR24321 1 253 2.8E-54 T 13-09-2016 THL1_RS19160 1e18c81b380f609e1aa5e5df9c9a0baa 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.6E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19160 1e18c81b380f609e1aa5e5df9c9a0baa 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.6E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19160 1e18c81b380f609e1aa5e5df9c9a0baa 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.6E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19160 1e18c81b380f609e1aa5e5df9c9a0baa 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.2E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19160 1e18c81b380f609e1aa5e5df9c9a0baa 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.2E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19160 1e18c81b380f609e1aa5e5df9c9a0baa 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.2E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19160 1e18c81b380f609e1aa5e5df9c9a0baa 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.2E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19160 1e18c81b380f609e1aa5e5df9c9a0baa 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.2E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19160 1e18c81b380f609e1aa5e5df9c9a0baa 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.2E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12695 548fccb373cc5015e4e7314296fe323e 256 SMART SM00346 12 100 1.0E-19 T 13-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 THL1_RS12695 548fccb373cc5015e4e7314296fe323e 256 SUPERFAMILY SSF55781 76 252 8.83E-43 T 13-09-2016 IPR029016 GAF domain-like THL1_RS12695 548fccb373cc5015e4e7314296fe323e 256 SUPERFAMILY SSF46785 14 83 7.89E-10 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12695 548fccb373cc5015e4e7314296fe323e 256 PANTHER PTHR30136:SF10 8 256 6.9E-56 T 13-09-2016 THL1_RS12695 548fccb373cc5015e4e7314296fe323e 256 TIGRFAM TIGR02431 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 9 254 7.7E-88 T 13-09-2016 IPR012794 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR GO:0003677|GO:0045893|GO:0046278 THL1_RS12695 548fccb373cc5015e4e7314296fe323e 256 Pfam PF01614 Bacterial transcriptional regulator 130 247 5.9E-26 T 13-09-2016 IPR014757 Transcription regulator IclR, C-terminal THL1_RS12695 548fccb373cc5015e4e7314296fe323e 256 Gene3D G3DSA:1.10.10.10 6 71 3.1E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12695 548fccb373cc5015e4e7314296fe323e 256 PANTHER PTHR30136 8 256 6.9E-56 T 13-09-2016 THL1_RS12695 548fccb373cc5015e4e7314296fe323e 256 Gene3D G3DSA:3.30.450.40 78 252 5.6E-46 T 13-09-2016 IPR029016 GAF domain-like THL1_RS12695 548fccb373cc5015e4e7314296fe323e 256 Pfam PF09339 IclR helix-turn-helix domain 15 65 2.6E-11 T 13-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 THL1_RS06995 6f50c5de8941b08412ef46a686c767c9 365 Gene3D G3DSA:1.10.10.10 300 362 5.7E-12 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS06995 6f50c5de8941b08412ef46a686c767c9 365 SUPERFAMILY SSF46894 293 362 5.44E-12 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS06995 6f50c5de8941b08412ef46a686c767c9 365 SUPERFAMILY SSF55785 173 224 5.71E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS06995 6f50c5de8941b08412ef46a686c767c9 365 Pfam PF00196 Bacterial regulatory proteins, luxR family 305 358 5.8E-6 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS06995 6f50c5de8941b08412ef46a686c767c9 365 SMART SM00421 302 359 6.4E-8 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS06995 6f50c5de8941b08412ef46a686c767c9 365 Gene3D G3DSA:3.30.450.20 173 224 2.2E-4 T 13-09-2016 THL1_RS11025 aa7afe764a0178889238c34db0216c93 216 PANTHER PTHR30086:SF13 2 214 7.7E-85 T 13-09-2016 THL1_RS11025 aa7afe764a0178889238c34db0216c93 216 PANTHER PTHR30086 2 214 7.7E-85 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS11025 aa7afe764a0178889238c34db0216c93 216 PIRSF PIRSF006324 1 208 1.5E-42 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS11025 aa7afe764a0178889238c34db0216c93 216 Pfam PF01810 LysE type translocator 16 206 5.0E-34 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 SUPERFAMILY SSF81464 6 103 3.11E-24 T 13-09-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 PANTHER PTHR22888 1 266 3.1E-122 T 13-09-2016 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 SUPERFAMILY SSF46626 259 355 8.45E-23 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 PRINTS PR01166 Cytochrome c oxidase subunit II signature 178 198 2.5E-39 T 13-09-2016 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 PRINTS PR01166 Cytochrome c oxidase subunit II signature 198 215 2.5E-39 T 13-09-2016 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 PRINTS PR01166 Cytochrome c oxidase subunit II signature 73 85 2.5E-39 T 13-09-2016 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 PRINTS PR01166 Cytochrome c oxidase subunit II signature 107 126 2.5E-39 T 13-09-2016 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 PRINTS PR01166 Cytochrome c oxidase subunit II signature 154 175 2.5E-39 T 13-09-2016 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 PRINTS PR01166 Cytochrome c oxidase subunit II signature 85 105 2.5E-39 T 13-09-2016 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 PRINTS PR01166 Cytochrome c oxidase subunit II signature 216 233 2.5E-39 T 13-09-2016 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 113 233 2.2E-37 T 13-09-2016 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 15 96 8.6E-13 T 13-09-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 24 243 3.0E-56 T 13-09-2016 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 Gene3D G3DSA:1.10.287.90 15 101 1.1E-23 T 13-09-2016 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 Gene3D G3DSA:2.60.40.420 102 279 1.5E-56 T 13-09-2016 IPR008972 Cupredoxin THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 Gene3D G3DSA:1.10.760.10 280 365 1.7E-25 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 266 340 2.4E-12 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 PANTHER PTHR22888:SF2 1 266 3.1E-122 T 13-09-2016 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 179 227 - T 13-09-2016 IPR001505 Copper centre Cu(A) GO:0005507 THL1_RS00250 4b1ec4224e0c91e105c47c2e7167f281 367 SUPERFAMILY SSF49503 105 298 3.35E-52 T 13-09-2016 IPR008972 Cupredoxin THL1_RS19835 8a1dfc3bf40e7021be3e59c61f857167 275 PANTHER PTHR24422:SF9 5 275 1.5E-115 T 13-09-2016 THL1_RS19835 8a1dfc3bf40e7021be3e59c61f857167 275 PRINTS PR00996 Glutamate methyltransferase family signature 66 78 4.7E-42 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS19835 8a1dfc3bf40e7021be3e59c61f857167 275 PRINTS PR00996 Glutamate methyltransferase family signature 105 125 4.7E-42 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS19835 8a1dfc3bf40e7021be3e59c61f857167 275 PRINTS PR00996 Glutamate methyltransferase family signature 143 159 4.7E-42 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS19835 8a1dfc3bf40e7021be3e59c61f857167 275 PRINTS PR00996 Glutamate methyltransferase family signature 212 226 4.7E-42 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS19835 8a1dfc3bf40e7021be3e59c61f857167 275 PRINTS PR00996 Glutamate methyltransferase family signature 231 254 4.7E-42 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS19835 8a1dfc3bf40e7021be3e59c61f857167 275 PRINTS PR00996 Glutamate methyltransferase family signature 27 40 4.7E-42 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS19835 8a1dfc3bf40e7021be3e59c61f857167 275 PANTHER PTHR24422 5 275 1.5E-115 T 13-09-2016 THL1_RS19835 8a1dfc3bf40e7021be3e59c61f857167 275 SUPERFAMILY SSF47757 6 72 2.22E-14 T 13-09-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THL1_RS19835 8a1dfc3bf40e7021be3e59c61f857167 275 Pfam PF03705 CheR methyltransferase, all-alpha domain 7 55 2.1E-11 T 13-09-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THL1_RS19835 8a1dfc3bf40e7021be3e59c61f857167 275 Gene3D G3DSA:1.10.155.10 7 71 2.0E-12 T 13-09-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THL1_RS19835 8a1dfc3bf40e7021be3e59c61f857167 275 SMART SM00138 5 272 8.1E-93 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS19835 8a1dfc3bf40e7021be3e59c61f857167 275 Pfam PF01739 CheR methyltransferase, SAM binding domain 73 269 2.6E-64 T 13-09-2016 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal THL1_RS19835 8a1dfc3bf40e7021be3e59c61f857167 275 SUPERFAMILY SSF53335 73 267 3.14E-47 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS19835 8a1dfc3bf40e7021be3e59c61f857167 275 Gene3D G3DSA:3.40.50.150 72 270 4.8E-62 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS20080 e01a2d83c72040e46eacabb48254f854 313 Gene3D G3DSA:1.20.1510.10 22 235 3.8E-50 T 13-09-2016 IPR027469 Cation efflux protein transmembrane domain THL1_RS20080 e01a2d83c72040e46eacabb48254f854 313 PANTHER PTHR11562:SF40 4 308 1.2E-147 T 13-09-2016 THL1_RS20080 e01a2d83c72040e46eacabb48254f854 313 SUPERFAMILY SSF161111 22 236 3.53E-49 T 13-09-2016 THL1_RS20080 e01a2d83c72040e46eacabb48254f854 313 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 23 310 3.0E-63 T 13-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THL1_RS20080 e01a2d83c72040e46eacabb48254f854 313 PANTHER PTHR11562 4 308 1.2E-147 T 13-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THL1_RS20080 e01a2d83c72040e46eacabb48254f854 313 Pfam PF01545 Cation efflux family 27 235 2.7E-40 T 13-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THL1_RS19230 59e21be4543b7af934f80d371a24b884 308 Pfam PF00990 Diguanylate cyclase, GGDEF domain 147 303 3.0E-45 T 13-09-2016 IPR000160 GGDEF domain THL1_RS19230 59e21be4543b7af934f80d371a24b884 308 PANTHER PTHR10799 36 44 3.2E-25 T 13-09-2016 THL1_RS19230 59e21be4543b7af934f80d371a24b884 308 SUPERFAMILY SSF55073 152 305 4.39E-46 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS19230 59e21be4543b7af934f80d371a24b884 308 Gene3D G3DSA:3.30.70.270 149 306 1.5E-51 T 13-09-2016 THL1_RS19230 59e21be4543b7af934f80d371a24b884 308 PANTHER PTHR10799:SF750 36 44 3.2E-25 T 13-09-2016 THL1_RS19230 59e21be4543b7af934f80d371a24b884 308 PANTHER PTHR10799:SF750 180 306 3.2E-25 T 13-09-2016 THL1_RS19230 59e21be4543b7af934f80d371a24b884 308 PANTHER PTHR10799 180 306 3.2E-25 T 13-09-2016 THL1_RS19230 59e21be4543b7af934f80d371a24b884 308 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 146 306 1.1E-49 T 13-09-2016 IPR000160 GGDEF domain THL1_RS19230 59e21be4543b7af934f80d371a24b884 308 SMART SM00267 135 307 1.9E-56 T 13-09-2016 IPR000160 GGDEF domain THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 Gene3D G3DSA:1.25.10.10 498 563 9.9E-4 T 13-09-2016 IPR011989 Armadillo-like helical THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 Gene3D G3DSA:1.10.710.10 383 433 3.2E-40 T 13-09-2016 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674|UniPathway: UPA00653 THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 Gene3D G3DSA:1.10.710.10 183 274 3.2E-40 T 13-09-2016 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674|UniPathway: UPA00653 THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 Gene3D G3DSA:1.10.710.10 313 351 3.2E-40 T 13-09-2016 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674|UniPathway: UPA00653 THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 Gene3D G3DSA:1.10.710.10 55 99 3.2E-40 T 13-09-2016 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674|UniPathway: UPA00653 THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 SUPERFAMILY SSF48371 461 559 3.64E-5 T 13-09-2016 IPR016024 Armadillo-type fold GO:0005488 THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 PANTHER PTHR23083 569 765 1.8E-15 T 13-09-2016 THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 SUPERFAMILY SSF48452 574 730 2.34E-17 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 SUPERFAMILY SSF48695 309 458 5.78E-61 T 13-09-2016 IPR011031 Multihaem cytochrome THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 SUPERFAMILY SSF48695 57 86 5.78E-61 T 13-09-2016 IPR011031 Multihaem cytochrome THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 SUPERFAMILY SSF48695 136 272 5.78E-61 T 13-09-2016 IPR011031 Multihaem cytochrome THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 Pfam PF09699 Doubled CXXCH motif (Paired_CXXCH_1) 324 353 5.9E-6 T 13-09-2016 IPR010177 Doubled CXXCH motif UniPathway: UPA00045 THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 Gene3D G3DSA:1.25.40.10 564 765 9.8E-27 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 SMART SM00028 592 625 0.7 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 SMART SM00028 660 693 5.7 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 PANTHER PTHR23083:SF396 569 765 1.8E-15 T 13-09-2016 THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 Pfam PF13435 Cytochrome c554 and c-prime 62 87 0.0061 T 13-09-2016 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674|UniPathway: UPA00653 THL1_RS27205 33514f73f86a5efcde2d636598ae33b8 767 Pfam PF13435 Cytochrome c554 and c-prime 191 230 2.3E-4 T 13-09-2016 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674|UniPathway: UPA00653 THL1_RS20845 3ed51947946803345340ad3862aea008 514 SUPERFAMILY SSF56801 11 511 4.84E-126 T 13-09-2016 THL1_RS20845 3ed51947946803345340ad3862aea008 514 Gene3D G3DSA:3.30.300.30 409 510 2.6E-28 T 13-09-2016 THL1_RS20845 3ed51947946803345340ad3862aea008 514 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS20845 3ed51947946803345340ad3862aea008 514 PANTHER PTHR24096 8 509 1.3E-193 T 13-09-2016 THL1_RS20845 3ed51947946803345340ad3862aea008 514 Gene3D G3DSA:3.40.50.980 169 331 2.5E-34 T 13-09-2016 THL1_RS20845 3ed51947946803345340ad3862aea008 514 Gene3D G3DSA:3.40.50.980 12 168 1.1E-30 T 13-09-2016 THL1_RS20845 3ed51947946803345340ad3862aea008 514 PANTHER PTHR24096:SF106 8 509 1.3E-193 T 13-09-2016 THL1_RS20845 3ed51947946803345340ad3862aea008 514 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 499 8.7E-18 T 13-09-2016 IPR025110 AMP-binding enzyme C-terminal domain THL1_RS20845 3ed51947946803345340ad3862aea008 514 Pfam PF00501 AMP-binding enzyme 12 412 1.3E-69 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS20845 3ed51947946803345340ad3862aea008 514 Gene3D G3DSA:2.30.38.10 340 406 5.6E-12 T 13-09-2016 THL1_RS03950 abc82bd8747657755c2c3e33daab8e14 312 SUPERFAMILY SSF53335 11 287 1.84E-51 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS03950 abc82bd8747657755c2c3e33daab8e14 312 Gene3D G3DSA:3.40.50.150 72 311 4.6E-56 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS03950 abc82bd8747657755c2c3e33daab8e14 312 PANTHER PTHR11061 1 267 2.0E-97 T 13-09-2016 THL1_RS03950 abc82bd8747657755c2c3e33daab8e14 312 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 25 310 6.0E-149 T 13-09-2016 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 THL1_RS03950 abc82bd8747657755c2c3e33daab8e14 312 PANTHER PTHR11061:SF34 1 267 2.0E-97 T 13-09-2016 THL1_RS19705 192c1c7485d354dd5f7daf9dd4ea01d9 445 Pfam PF07559 Flagellar basal body protein FlaE 176 326 1.5E-29 T 13-09-2016 IPR011491 Flagellar hook protein FlgE THL1_RS19705 192c1c7485d354dd5f7daf9dd4ea01d9 445 Pfam PF00460 Flagella basal body rod protein 3 33 4.5E-7 T 13-09-2016 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 THL1_RS19705 192c1c7485d354dd5f7daf9dd4ea01d9 445 PANTHER PTHR30435 1 123 5.4E-94 T 13-09-2016 THL1_RS19705 192c1c7485d354dd5f7daf9dd4ea01d9 445 PANTHER PTHR30435:SF1 1 123 5.4E-94 T 13-09-2016 THL1_RS19705 192c1c7485d354dd5f7daf9dd4ea01d9 445 PANTHER PTHR30435:SF1 323 445 5.4E-94 T 13-09-2016 THL1_RS19705 192c1c7485d354dd5f7daf9dd4ea01d9 445 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 380 444 1.3E-16 T 13-09-2016 IPR010930 Flagellar basal-body/hook protein, C-terminal domain THL1_RS19705 192c1c7485d354dd5f7daf9dd4ea01d9 445 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 1 427 3.1E-100 T 13-09-2016 IPR020013 Fagellar hook-basal body protein, FlgE/F/G THL1_RS19705 192c1c7485d354dd5f7daf9dd4ea01d9 445 SUPERFAMILY SSF117143 80 255 1.44E-76 T 13-09-2016 THL1_RS19705 192c1c7485d354dd5f7daf9dd4ea01d9 445 SUPERFAMILY SSF117143 285 406 1.44E-76 T 13-09-2016 THL1_RS19705 192c1c7485d354dd5f7daf9dd4ea01d9 445 PANTHER PTHR30435 323 445 5.4E-94 T 13-09-2016 THL1_RS26030 d558f694f90564c58df9b756a6aecb9d 423 SUPERFAMILY SSF53756 54 415 4.93E-15 T 13-09-2016 THL1_RS26030 d558f694f90564c58df9b756a6aecb9d 423 PANTHER PTHR23417 1 111 5.0E-131 T 13-09-2016 THL1_RS26030 d558f694f90564c58df9b756a6aecb9d 423 PANTHER PTHR23417 130 140 5.0E-131 T 13-09-2016 THL1_RS26030 d558f694f90564c58df9b756a6aecb9d 423 PANTHER PTHR23417 190 421 5.0E-131 T 13-09-2016 THL1_RS26030 d558f694f90564c58df9b756a6aecb9d 423 PANTHER PTHR23417:SF2 1 111 5.0E-131 T 13-09-2016 THL1_RS26030 d558f694f90564c58df9b756a6aecb9d 423 PANTHER PTHR23417:SF2 130 140 5.0E-131 T 13-09-2016 THL1_RS26030 d558f694f90564c58df9b756a6aecb9d 423 PANTHER PTHR23417:SF2 190 421 5.0E-131 T 13-09-2016 THL1_RS26030 d558f694f90564c58df9b756a6aecb9d 423 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 34 210 4.1E-68 T 13-09-2016 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675|UniPathway: UPA00958 THL1_RS27175 2853cb42b163815ed862a0eb4958c815 228 Pfam PF04367 Protein of unknown function (DUF502) 72 175 5.2E-10 T 13-09-2016 IPR007462 Protein of unknown function DUF502 THL1_RS27175 2853cb42b163815ed862a0eb4958c815 228 PANTHER PTHR31876:SF1 3 208 2.0E-36 T 13-09-2016 THL1_RS27175 2853cb42b163815ed862a0eb4958c815 228 PANTHER PTHR31876 3 208 2.0E-36 T 13-09-2016 THL1_RS21740 d2c9f51914406bcc9fd7a54a85307cbd 578 Gene3D G3DSA:3.40.50.300 331 556 2.1E-60 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21740 d2c9f51914406bcc9fd7a54a85307cbd 578 Gene3D G3DSA:1.20.1560.10 12 313 2.0E-41 T 13-09-2016 THL1_RS21740 d2c9f51914406bcc9fd7a54a85307cbd 578 TIGRFAM TIGR01842 type_I_sec_PrtD: type I secretion system ATPase 16 557 1.1E-238 T 13-09-2016 IPR010128 ATPase, type I secretion system, PrtD GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 THL1_RS21740 d2c9f51914406bcc9fd7a54a85307cbd 578 SMART SM00382 357 543 8.7E-13 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS21740 d2c9f51914406bcc9fd7a54a85307cbd 578 Pfam PF00005 ABC transporter 348 495 2.0E-29 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS21740 d2c9f51914406bcc9fd7a54a85307cbd 578 SUPERFAMILY SSF90123 11 320 3.4E-46 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS21740 d2c9f51914406bcc9fd7a54a85307cbd 578 ProSitePatterns PS00211 ABC transporters family signature. 468 482 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS21740 d2c9f51914406bcc9fd7a54a85307cbd 578 Pfam PF00664 ABC transporter transmembrane region 33 280 1.8E-15 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS21740 d2c9f51914406bcc9fd7a54a85307cbd 578 SUPERFAMILY SSF52540 320 555 2.76E-63 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21740 d2c9f51914406bcc9fd7a54a85307cbd 578 PANTHER PTHR24222 10 559 4.0E-261 T 13-09-2016 THL1_RS21740 d2c9f51914406bcc9fd7a54a85307cbd 578 PANTHER PTHR24222:SF0 10 559 4.0E-261 T 13-09-2016 IPR010128 ATPase, type I secretion system, PrtD GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 THL1_RS09165 c0cf4228ad275ed53f8f0d80f392485c 680 PANTHER PTHR11757 16 680 9.3E-301 T 13-09-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 THL1_RS09165 c0cf4228ad275ed53f8f0d80f392485c 680 PANTHER PTHR11757:SF3 16 680 9.3E-301 T 13-09-2016 THL1_RS09165 c0cf4228ad275ed53f8f0d80f392485c 680 Gene3D G3DSA:3.40.50.1820 418 659 5.6E-38 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS09165 c0cf4228ad275ed53f8f0d80f392485c 680 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 471 495 7.5E-52 T 13-09-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 THL1_RS09165 c0cf4228ad275ed53f8f0d80f392485c 680 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 605 627 7.5E-52 T 13-09-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 THL1_RS09165 c0cf4228ad275ed53f8f0d80f392485c 680 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 445 463 7.5E-52 T 13-09-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 THL1_RS09165 c0cf4228ad275ed53f8f0d80f392485c 680 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 499 518 7.5E-52 T 13-09-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 THL1_RS09165 c0cf4228ad275ed53f8f0d80f392485c 680 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 529 549 7.5E-52 T 13-09-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 THL1_RS09165 c0cf4228ad275ed53f8f0d80f392485c 680 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 587 602 7.5E-52 T 13-09-2016 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 THL1_RS09165 c0cf4228ad275ed53f8f0d80f392485c 680 SUPERFAMILY SSF50993 16 410 1.26E-81 T 13-09-2016 THL1_RS09165 c0cf4228ad275ed53f8f0d80f392485c 680 SUPERFAMILY SSF53474 415 664 3.04E-45 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS09165 c0cf4228ad275ed53f8f0d80f392485c 680 Pfam PF00326 Prolyl oligopeptidase family 461 676 7.1E-69 T 13-09-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 THL1_RS09165 c0cf4228ad275ed53f8f0d80f392485c 680 Gene3D G3DSA:2.130.10.120 65 405 9.4E-94 T 13-09-2016 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 THL1_RS09165 c0cf4228ad275ed53f8f0d80f392485c 680 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 16 402 4.9E-82 T 13-09-2016 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 THL1_RS22375 3a720bd464af601362372a319287fb96 440 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 6 439 61.734 T 13-09-2016 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 THL1_RS22375 3a720bd464af601362372a319287fb96 440 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 143 163 - T 13-09-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 THL1_RS22375 3a720bd464af601362372a319287fb96 440 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 7 437 1.9E-102 T 13-09-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 THL1_RS22375 3a720bd464af601362372a319287fb96 440 Gene3D G3DSA:3.80.30.20 137 376 1.3E-71 T 13-09-2016 IPR023404 Radical SAM, alpha/beta horseshoe THL1_RS22375 3a720bd464af601362372a319287fb96 440 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 7 436 1.4E-176 T 13-09-2016 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 THL1_RS22375 3a720bd464af601362372a319287fb96 440 PANTHER PTHR11918:SF57 6 440 1.8E-243 T 13-09-2016 THL1_RS22375 3a720bd464af601362372a319287fb96 440 PANTHER PTHR11918 6 440 1.8E-243 T 13-09-2016 IPR023970 Methylthiotransferase/radical SAM-type protein THL1_RS22375 3a720bd464af601362372a319287fb96 440 SMART SM00729 139 365 1.2E-51 T 13-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THL1_RS22375 3a720bd464af601362372a319287fb96 440 Pfam PF04055 Radical SAM superfamily 145 322 1.9E-28 T 13-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 THL1_RS22375 3a720bd464af601362372a319287fb96 440 Pfam PF00919 Uncharacterized protein family UPF0004 7 99 3.9E-21 T 13-09-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 THL1_RS22375 3a720bd464af601362372a319287fb96 440 Gene3D G3DSA:2.40.50.140 380 440 1.9E-25 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS22375 3a720bd464af601362372a319287fb96 440 SUPERFAMILY SSF102114 111 370 8.63E-53 T 13-09-2016 THL1_RS07060 98f0e9a412a9473efe4188425493d42f 357 PANTHER PTHR32332:SF20 5 238 2.0E-84 T 13-09-2016 THL1_RS07060 98f0e9a412a9473efe4188425493d42f 357 PANTHER PTHR32332:SF20 273 349 2.0E-84 T 13-09-2016 THL1_RS07060 98f0e9a412a9473efe4188425493d42f 357 Gene3D G3DSA:3.20.20.70 5 336 2.2E-65 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS07060 98f0e9a412a9473efe4188425493d42f 357 SUPERFAMILY SSF51412 5 250 1.42E-55 T 13-09-2016 THL1_RS07060 98f0e9a412a9473efe4188425493d42f 357 PANTHER PTHR32332 273 349 2.0E-84 T 13-09-2016 THL1_RS07060 98f0e9a412a9473efe4188425493d42f 357 Pfam PF03060 Nitronate monooxygenase 7 341 2.0E-71 T 13-09-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 THL1_RS07060 98f0e9a412a9473efe4188425493d42f 357 PANTHER PTHR32332 5 238 2.0E-84 T 13-09-2016 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 SUPERFAMILY SSF52172 482 605 1.02E-29 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 Gene3D G3DSA:3.30.450.20 107 241 3.2E-16 T 13-09-2016 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 SUPERFAMILY SSF47226 583 705 3.4E-14 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 Gene3D G3DSA:3.40.50.2300 482 604 6.3E-32 T 13-09-2016 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 460 2.4E-27 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 Gene3D G3DSA:3.30.565.10 300 461 2.2E-43 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 Pfam PF00072 Response regulator receiver domain 486 599 3.0E-19 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 SUPERFAMILY SSF55874 289 460 5.11E-44 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 SUPERFAMILY SSF47384 219 301 5.49E-16 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 PANTHER PTHR24423 86 640 4.2E-152 T 13-09-2016 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 109 223 4.8E-11 T 13-09-2016 IPR000014 PAS domain THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 3.2E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 415 3.2E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 401 3.2E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 459 3.2E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 SUPERFAMILY SSF55785 86 214 2.44E-18 T 13-09-2016 IPR000014 PAS domain THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 SMART SM00387 346 462 1.0E-33 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 PANTHER PTHR24423:SF382 86 640 4.2E-152 T 13-09-2016 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 299 8.3E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 SMART SM00091 101 169 1.6E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 SMART SM00388 236 299 1.0E-15 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 Gene3D G3DSA:1.20.120.160 619 721 8.3E-10 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 Pfam PF08448 PAS fold 107 217 3.3E-9 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 Pfam PF01627 Hpt domain 639 723 2.6E-7 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 Gene3D G3DSA:1.10.287.130 242 294 3.5E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24975 54ce4904e7cadca10de5bcbc9ab36eba 729 SMART SM00448 484 600 5.5E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS13350 723ab818f14d58929d601c8995a488ac 361 SUPERFAMILY SSF111369 192 306 4.97E-13 T 13-09-2016 THL1_RS13350 723ab818f14d58929d601c8995a488ac 361 PANTHER PTHR30386:SF0 1 359 1.6E-78 T 13-09-2016 THL1_RS13350 723ab818f14d58929d601c8995a488ac 361 PANTHER PTHR30386 1 359 1.6E-78 T 13-09-2016 THL1_RS13350 723ab818f14d58929d601c8995a488ac 361 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 67 309 6.9E-19 T 13-09-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THL1_RS13350 723ab818f14d58929d601c8995a488ac 361 Gene3D G3DSA:2.40.50.100 68 100 2.7E-19 T 13-09-2016 THL1_RS13350 723ab818f14d58929d601c8995a488ac 361 Gene3D G3DSA:2.40.50.100 231 263 2.7E-19 T 13-09-2016 THL1_RS13350 723ab818f14d58929d601c8995a488ac 361 SUPERFAMILY SSF111369 67 127 2.09E-9 T 13-09-2016 THL1_RS08450 cbd19457fa4c67f2dde7173237fae36f 206 PIRSF PIRSF005461 1 206 4.4E-77 T 13-09-2016 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 THL1_RS08450 cbd19457fa4c67f2dde7173237fae36f 206 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 8 204 29.379 T 13-09-2016 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 THL1_RS08450 cbd19457fa4c67f2dde7173237fae36f 206 Gene3D G3DSA:3.40.50.150 2 205 1.0E-69 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS08450 cbd19457fa4c67f2dde7173237fae36f 206 PANTHER PTHR10920:SF20 1 206 7.9E-109 T 13-09-2016 THL1_RS08450 cbd19457fa4c67f2dde7173237fae36f 206 PANTHER PTHR10920 1 206 7.9E-109 T 13-09-2016 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 THL1_RS08450 cbd19457fa4c67f2dde7173237fae36f 206 Pfam PF01728 FtsJ-like methyltransferase 28 204 2.9E-55 T 13-09-2016 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 THL1_RS08450 cbd19457fa4c67f2dde7173237fae36f 206 SUPERFAMILY SSF53335 2 206 5.57E-41 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS14005 e4dd51de08b511d3f46371acec33f176 536 SUPERFAMILY SSF52518 1 175 6.92E-51 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS14005 e4dd51de08b511d3f46371acec33f176 536 Gene3D G3DSA:3.40.50.970 2 177 1.2E-55 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS14005 e4dd51de08b511d3f46371acec33f176 536 PANTHER PTHR18968 1 528 8.1E-151 T 13-09-2016 THL1_RS14005 e4dd51de08b511d3f46371acec33f176 536 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 191 324 1.4E-29 T 13-09-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 THL1_RS14005 e4dd51de08b511d3f46371acec33f176 536 PANTHER PTHR18968:SF13 1 528 8.1E-151 T 13-09-2016 THL1_RS14005 e4dd51de08b511d3f46371acec33f176 536 Gene3D G3DSA:3.40.50.1220 184 373 7.8E-39 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS14005 e4dd51de08b511d3f46371acec33f176 536 SUPERFAMILY SSF52467 156 349 7.32E-38 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS14005 e4dd51de08b511d3f46371acec33f176 536 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 171 3.0E-50 T 13-09-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 THL1_RS14005 e4dd51de08b511d3f46371acec33f176 536 Gene3D G3DSA:3.40.50.970 374 529 1.5E-51 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS14005 e4dd51de08b511d3f46371acec33f176 536 SUPERFAMILY SSF52518 362 530 1.97E-49 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS14005 e4dd51de08b511d3f46371acec33f176 536 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 419 438 - T 13-09-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 THL1_RS14005 e4dd51de08b511d3f46371acec33f176 536 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 528 5.9E-37 T 13-09-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THL1_RS17115 2afe97e01b180dd14760404948839fc1 134 Gene3D G3DSA:3.40.190.10 39 130 2.9E-6 T 13-09-2016 THL1_RS17115 2afe97e01b180dd14760404948839fc1 134 SUPERFAMILY SSF53850 20 130 5.43E-11 T 13-09-2016 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 SUPERFAMILY SSF52540 368 415 8.51E-87 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 SUPERFAMILY SSF52540 5 228 8.51E-87 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 Pfam PF02810 SEC-C motif 897 915 1.9E-10 T 13-09-2016 IPR004027 SEC-C motif THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 Pfam PF07517 SecA DEAD-like domain 6 402 4.3E-132 T 13-09-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 SMART SM00958 228 358 1.6E-70 T 13-09-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 Gene3D G3DSA:1.10.3060.10 648 831 7.8E-60 T 13-09-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 PANTHER PTHR30612 5 520 0.0 T 13-09-2016 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 PANTHER PTHR30612 550 917 0.0 T 13-09-2016 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 Gene3D G3DSA:3.40.50.300 417 619 2.9E-91 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 SUPERFAMILY SSF52540 416 618 1.82E-58 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 SUPERFAMILY SSF81886 620 840 5.75E-83 T 13-09-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 SUPERFAMILY SSF81886 893 905 5.75E-83 T 13-09-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 ProSitePatterns PS01312 SecA family signature. 500 515 - T 13-09-2016 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 Gene3D G3DSA:3.90.1440.10 230 368 1.5E-41 T 13-09-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 Gene3D G3DSA:3.40.50.300 3 228 1.8E-128 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 Gene3D G3DSA:3.40.50.300 369 416 1.8E-128 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 818 0.0 T 13-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 SMART SM00957 6 402 6.1E-302 T 13-09-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 Pfam PF07516 SecA Wing and Scaffold domain 617 830 2.5E-68 T 13-09-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 PRINTS PR00906 SecA protein signature 413 426 1.7E-69 T 13-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 PRINTS PR00906 SecA protein signature 170 190 1.7E-69 T 13-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 PRINTS PR00906 SecA protein signature 376 393 1.7E-69 T 13-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 PRINTS PR00906 SecA protein signature 117 127 1.7E-69 T 13-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 PRINTS PR00906 SecA protein signature 63 87 1.7E-69 T 13-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 PRINTS PR00906 SecA protein signature 101 115 1.7E-69 T 13-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 PRINTS PR00906 SecA protein signature 339 361 1.7E-69 T 13-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 832 20.025 T 13-09-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 SUPERFAMILY SSF81767 227 368 7.72E-40 T 13-09-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 THL1_RS05685 febbb18eec444de4799c739ae537b3b8 917 Pfam PF01043 SecA preprotein cross-linking domain 232 358 1.3E-33 T 13-09-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 THL1_RS02555 99ef6516571ab2065febb663d6181318 117 Pfam PF02152 Dihydroneopterin aldolase 4 113 1.1E-30 T 13-09-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 THL1_RS02555 99ef6516571ab2065febb663d6181318 117 PANTHER PTHR20941 2 117 4.4E-24 T 13-09-2016 THL1_RS02555 99ef6516571ab2065febb663d6181318 117 TIGRFAM TIGR00526 folB_dom: FolB domain 2 115 3.6E-31 T 13-09-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 THL1_RS02555 99ef6516571ab2065febb663d6181318 117 Gene3D G3DSA:3.30.1130.10 2 114 2.6E-38 T 13-09-2016 THL1_RS02555 99ef6516571ab2065febb663d6181318 117 SMART SM00905 4 114 4.1E-47 T 13-09-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 THL1_RS02555 99ef6516571ab2065febb663d6181318 117 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 114 2.4E-24 T 13-09-2016 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 THL1_RS02555 99ef6516571ab2065febb663d6181318 117 SUPERFAMILY SSF55620 2 115 3.61E-34 T 13-09-2016 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 356 5.1E-52 T 13-09-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 506 519 5.1E-52 T 13-09-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 463 491 5.1E-52 T 13-09-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 533 545 5.1E-52 T 13-09-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 384 5.1E-52 T 13-09-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 171 218 3.8E-15 T 13-09-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 629 4.4E-224 T 13-09-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 Gene3D G3DSA:3.40.50.800 530 633 8.9E-31 T 13-09-2016 IPR004154 Anticodon-binding THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 SUPERFAMILY SSF52954 528 632 7.1E-30 T 13-09-2016 IPR004154 Anticodon-binding THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 SUPERFAMILY SSF81271 3 61 7.85E-15 T 13-09-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 PANTHER PTHR11451:SF31 1 640 0.0 T 13-09-2016 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 Gene3D G3DSA:3.30.54.20 130 186 4.5E-18 T 13-09-2016 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 Gene3D G3DSA:3.30.930.10 241 529 1.7E-123 T 13-09-2016 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 Gene3D G3DSA:3.30.980.10 65 129 1.2E-40 T 13-09-2016 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 Gene3D G3DSA:3.30.980.10 187 223 1.2E-40 T 13-09-2016 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 633 34.059 T 13-09-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 Gene3D G3DSA:3.10.20.30 1 64 3.2E-22 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 SUPERFAMILY SSF55186 63 240 3.14E-64 T 13-09-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 SMART SM00863 169 218 9.7E-22 T 13-09-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 PANTHER PTHR11451 1 640 0.0 T 13-09-2016 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 Pfam PF03129 Anticodon binding domain 540 628 3.6E-19 T 13-09-2016 IPR004154 Anticodon-binding THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 SUPERFAMILY SSF55681 242 525 6.51E-101 T 13-09-2016 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 320 528 1.6E-45 T 13-09-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS17595 8491f8bdf396578b4518f448f5ee3bfd 640 Pfam PF02824 TGS domain 4 61 2.6E-11 T 13-09-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 THL1_RS23535 da1869c5aa38e75842385646821503c0 455 Pfam PF07044 Protein of unknown function (DUF1329) 83 450 3.4E-152 T 13-09-2016 IPR010752 Protein of unknown function DUF1329 THL1_RS23535 da1869c5aa38e75842385646821503c0 455 Gene3D G3DSA:2.50.20.10 342 430 1.0E-34 T 13-09-2016 THL1_RS23535 da1869c5aa38e75842385646821503c0 455 Gene3D G3DSA:2.50.20.10 161 309 1.0E-34 T 13-09-2016 THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 PANTHER PTHR11902 1 429 1.3E-276 T 13-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 427 2.3E-203 T 13-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 SMART SM01192 143 429 4.9E-219 T 13-09-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 Hamap MF_00318 Enolase [eno]. 2 415 44.22 T 13-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 Gene3D G3DSA:3.30.390.10 3 126 6.1E-55 T 13-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 SUPERFAMILY SSF54826 3 138 1.51E-56 T 13-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 PRINTS PR00148 Enolase signature 367 384 1.2E-44 T 13-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 PRINTS PR00148 Enolase signature 107 123 1.2E-44 T 13-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 PRINTS PR00148 Enolase signature 37 51 1.2E-44 T 13-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 PRINTS PR00148 Enolase signature 165 178 1.2E-44 T 13-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 PRINTS PR00148 Enolase signature 338 352 1.2E-44 T 13-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 PRINTS PR00148 Enolase signature 315 326 1.2E-44 T 13-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 PIRSF PIRSF001400 1 429 1.0E-191 T 13-09-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 Pfam PF03952 Enolase, N-terminal domain 4 134 1.5E-58 T 13-09-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 SUPERFAMILY SSF51604 143 427 1.97E-127 T 13-09-2016 IPR029065 Enolase C-terminal domain-like THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 SMART SM01193 4 134 1.2E-92 T 13-09-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 ProSitePatterns PS00164 Enolase signature. 338 351 - T 13-09-2016 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 Gene3D G3DSA:3.20.20.120 128 427 6.0E-137 T 13-09-2016 IPR029065 Enolase C-terminal domain-like THL1_RS22540 53fcc83eddbb5543d34dcc9d9f924dc9 429 Pfam PF00113 Enolase, C-terminal TIM barrel domain 144 426 4.9E-136 T 13-09-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 THL1_RS10965 bec8179419ebf89d9b211e60991f3fb7 239 Gene3D G3DSA:1.10.10.10 136 238 5.2E-30 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS10965 bec8179419ebf89d9b211e60991f3fb7 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 160 236 3.3E-24 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS10965 bec8179419ebf89d9b211e60991f3fb7 239 SMART SM00448 5 115 2.0E-38 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS10965 bec8179419ebf89d9b211e60991f3fb7 239 Pfam PF00072 Response regulator receiver domain 7 116 1.4E-26 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS10965 bec8179419ebf89d9b211e60991f3fb7 239 Gene3D G3DSA:3.40.50.2300 3 124 2.1E-37 T 13-09-2016 THL1_RS10965 bec8179419ebf89d9b211e60991f3fb7 239 SUPERFAMILY SSF52172 3 127 1.85E-40 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS10965 bec8179419ebf89d9b211e60991f3fb7 239 PANTHER PTHR26402:SF292 5 238 3.1E-85 T 13-09-2016 THL1_RS10965 bec8179419ebf89d9b211e60991f3fb7 239 PANTHER PTHR26402 5 238 3.1E-85 T 13-09-2016 THL1_RS10965 bec8179419ebf89d9b211e60991f3fb7 239 SUPERFAMILY SSF46894 136 237 9.07E-27 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS10965 bec8179419ebf89d9b211e60991f3fb7 239 SMART SM00862 160 236 1.0E-25 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS27355 36d5a1744e8769b82648007f1b3abcc3 156 PANTHER PTHR12418:SF35 19 154 9.8E-63 T 13-09-2016 THL1_RS27355 36d5a1744e8769b82648007f1b3abcc3 156 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 26 154 4.3E-16 T 13-09-2016 IPR003736 Phenylacetic acid degradation-related domain THL1_RS27355 36d5a1744e8769b82648007f1b3abcc3 156 SUPERFAMILY SSF54637 12 154 3.26E-28 T 13-09-2016 IPR029069 HotDog domain THL1_RS27355 36d5a1744e8769b82648007f1b3abcc3 156 Gene3D G3DSA:3.10.129.10 16 153 5.5E-33 T 13-09-2016 IPR029069 HotDog domain THL1_RS27355 36d5a1744e8769b82648007f1b3abcc3 156 PANTHER PTHR12418 19 154 9.8E-63 T 13-09-2016 THL1_RS27355 36d5a1744e8769b82648007f1b3abcc3 156 Pfam PF03061 Thioesterase superfamily 57 147 3.7E-18 T 13-09-2016 IPR006683 Thioesterase domain THL1_RS03630 77ff5eb62ac63cda504d02351d26302e 38 Pfam PF00444 Ribosomal protein L36 1 38 5.9E-21 T 13-09-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03630 77ff5eb62ac63cda504d02351d26302e 38 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 38 18.317 T 13-09-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03630 77ff5eb62ac63cda504d02351d26302e 38 SUPERFAMILY SSF57840 1 38 3.79E-17 T 13-09-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03630 77ff5eb62ac63cda504d02351d26302e 38 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 38 4.0E-10 T 13-09-2016 THL1_RS03630 77ff5eb62ac63cda504d02351d26302e 38 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 38 3.3E-22 T 13-09-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03630 77ff5eb62ac63cda504d02351d26302e 38 PANTHER PTHR18804 1 38 1.1E-19 T 13-09-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03630 77ff5eb62ac63cda504d02351d26302e 38 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 37 - T 13-09-2016 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS22670 385d8cde70ac6d712c36f2adad6b21a7 401 PANTHER PTHR11601:SF17 1 401 6.5E-150 T 13-09-2016 THL1_RS22670 385d8cde70ac6d712c36f2adad6b21a7 401 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 214 233 - T 13-09-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site THL1_RS22670 385d8cde70ac6d712c36f2adad6b21a7 401 SUPERFAMILY SSF53383 7 398 3.19E-108 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS22670 385d8cde70ac6d712c36f2adad6b21a7 401 Pfam PF00266 Aminotransferase class-V 24 389 8.9E-135 T 13-09-2016 IPR000192 Aminotransferase class V domain THL1_RS22670 385d8cde70ac6d712c36f2adad6b21a7 401 Gene3D G3DSA:3.40.640.10 35 275 9.1E-64 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS22670 385d8cde70ac6d712c36f2adad6b21a7 401 Gene3D G3DSA:3.90.1150.10 276 400 4.8E-41 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS22670 385d8cde70ac6d712c36f2adad6b21a7 401 PANTHER PTHR11601 1 401 6.5E-150 T 13-09-2016 THL1_RS09765 d45c08ce4a8d0fa4c0ab51f298c14f4d 543 SMART SM00990 426 540 1.4E-43 T 13-09-2016 IPR014883 VRR-NUC domain GO:0016788 THL1_RS09765 d45c08ce4a8d0fa4c0ab51f298c14f4d 543 Pfam PF08774 VRR-NUC domain 430 540 1.8E-31 T 13-09-2016 IPR014883 VRR-NUC domain GO:0016788 THL1_RS09765 d45c08ce4a8d0fa4c0ab51f298c14f4d 543 PANTHER PTHR15749:SF3 4 540 3.9E-184 T 13-09-2016 THL1_RS09765 d45c08ce4a8d0fa4c0ab51f298c14f4d 543 PANTHER PTHR15749 4 540 3.9E-184 T 13-09-2016 IPR033315 Fanconi-associated nuclease 1-like GO:0004518|GO:0036297 THL1_RS01870 0db1f4a5c5e38d712af4d420e9eadb4e 211 SMART SM00448 2 114 3.7E-33 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS01870 0db1f4a5c5e38d712af4d420e9eadb4e 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 200 2.0E-18 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS01870 0db1f4a5c5e38d712af4d420e9eadb4e 211 SMART SM00421 143 200 2.9E-17 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS01870 0db1f4a5c5e38d712af4d420e9eadb4e 211 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS01870 0db1f4a5c5e38d712af4d420e9eadb4e 211 SUPERFAMILY SSF46894 138 205 6.46E-17 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS01870 0db1f4a5c5e38d712af4d420e9eadb4e 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 3.7E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS01870 0db1f4a5c5e38d712af4d420e9eadb4e 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 3.7E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS01870 0db1f4a5c5e38d712af4d420e9eadb4e 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 3.7E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS01870 0db1f4a5c5e38d712af4d420e9eadb4e 211 Gene3D G3DSA:3.40.50.2300 4 126 3.8E-34 T 13-09-2016 THL1_RS01870 0db1f4a5c5e38d712af4d420e9eadb4e 211 Gene3D G3DSA:1.10.10.10 127 206 9.6E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS01870 0db1f4a5c5e38d712af4d420e9eadb4e 211 PANTHER PTHR26402 1 204 4.3E-60 T 13-09-2016 THL1_RS01870 0db1f4a5c5e38d712af4d420e9eadb4e 211 Pfam PF00072 Response regulator receiver domain 5 115 5.7E-30 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS01870 0db1f4a5c5e38d712af4d420e9eadb4e 211 SUPERFAMILY SSF52172 2 126 3.42E-33 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS01870 0db1f4a5c5e38d712af4d420e9eadb4e 211 PANTHER PTHR26402:SF151 1 204 4.3E-60 T 13-09-2016 THL1_RS25755 8c04e81f5772ae3e4cae73a22acb8811 1095 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 6 84 2.2E-27 T 13-09-2016 IPR013589 Bacterial transglutaminase-like, N-terminal THL1_RS25755 8c04e81f5772ae3e4cae73a22acb8811 1095 SUPERFAMILY SSF54001 8 337 4.07E-73 T 13-09-2016 THL1_RS25755 8c04e81f5772ae3e4cae73a22acb8811 1095 Pfam PF01841 Transglutaminase-like superfamily 133 246 1.9E-19 T 13-09-2016 IPR002931 Transglutaminase-like THL1_RS25755 8c04e81f5772ae3e4cae73a22acb8811 1095 PANTHER PTHR33490 2 509 9.0E-235 T 13-09-2016 THL1_RS25755 8c04e81f5772ae3e4cae73a22acb8811 1095 Pfam PF09899 Putative amidoligase enzyme (DUF2126) 276 1093 0.0 T 13-09-2016 IPR018667 Domain of unknown function DUF2126 THL1_RS25755 8c04e81f5772ae3e4cae73a22acb8811 1095 SMART SM00460 172 248 4.0E-19 T 13-09-2016 IPR002931 Transglutaminase-like THL1_RS25755 8c04e81f5772ae3e4cae73a22acb8811 1095 PANTHER PTHR33490:SF1 2 509 9.0E-235 T 13-09-2016 THL1_RS25755 8c04e81f5772ae3e4cae73a22acb8811 1095 Gene3D G3DSA:3.90.260.10 177 248 6.8E-11 T 13-09-2016 IPR002931 Transglutaminase-like THL1_RS18115 121a9491e7a441158bfdfeaebaa655a8 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 3.2E-24 T 13-09-2016 THL1_RS18115 121a9491e7a441158bfdfeaebaa655a8 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 3.2E-24 T 13-09-2016 THL1_RS18115 121a9491e7a441158bfdfeaebaa655a8 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 3.2E-24 T 13-09-2016 THL1_RS18115 121a9491e7a441158bfdfeaebaa655a8 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.2E-24 T 13-09-2016 THL1_RS18115 121a9491e7a441158bfdfeaebaa655a8 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 3.2E-24 T 13-09-2016 THL1_RS18115 121a9491e7a441158bfdfeaebaa655a8 333 SUPERFAMILY SSF51905 1 306 2.85E-48 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS18115 121a9491e7a441158bfdfeaebaa655a8 333 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 1.4E-14 T 13-09-2016 THL1_RS18115 121a9491e7a441158bfdfeaebaa655a8 333 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.4E-14 T 13-09-2016 THL1_RS18115 121a9491e7a441158bfdfeaebaa655a8 333 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 1.4E-14 T 13-09-2016 THL1_RS18115 121a9491e7a441158bfdfeaebaa655a8 333 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 1.4E-14 T 13-09-2016 THL1_RS18115 121a9491e7a441158bfdfeaebaa655a8 333 PANTHER PTHR22912 1 333 2.2E-133 T 13-09-2016 THL1_RS18115 121a9491e7a441158bfdfeaebaa655a8 333 PANTHER PTHR22912:SF1 1 333 2.2E-133 T 13-09-2016 THL1_RS18115 121a9491e7a441158bfdfeaebaa655a8 333 Gene3D G3DSA:3.50.50.60 106 306 4.7E-49 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS18115 121a9491e7a441158bfdfeaebaa655a8 333 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 283 3.4E-61 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS18115 121a9491e7a441158bfdfeaebaa655a8 333 Gene3D G3DSA:3.50.50.60 2 105 3.2E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS04335 0e92bd63e2386344accd161767a11a1b 181 SUPERFAMILY SSF81901 32 135 1.44E-23 T 13-09-2016 THL1_RS04335 0e92bd63e2386344accd161767a11a1b 181 Gene3D G3DSA:1.25.40.10 35 137 5.6E-29 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS04335 0e92bd63e2386344accd161767a11a1b 181 Pfam PF08238 Sel1 repeat 96 120 0.0045 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS04335 0e92bd63e2386344accd161767a11a1b 181 Pfam PF08238 Sel1 repeat 60 95 5.8E-10 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS04335 0e92bd63e2386344accd161767a11a1b 181 PANTHER PTHR11102:SF11 42 137 4.2E-20 T 13-09-2016 THL1_RS04335 0e92bd63e2386344accd161767a11a1b 181 PANTHER PTHR11102 42 137 4.2E-20 T 13-09-2016 THL1_RS04335 0e92bd63e2386344accd161767a11a1b 181 SMART SM00671 96 131 2.1E-6 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS04335 0e92bd63e2386344accd161767a11a1b 181 SMART SM00671 60 95 2.7E-10 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS10865 452701a1635c9721158d3d2b37d77303 238 Pfam PF13534 4Fe-4S dicluster domain 148 221 4.5E-9 T 13-09-2016 THL1_RS10865 452701a1635c9721158d3d2b37d77303 238 SUPERFAMILY SSF46548 108 235 1.74E-38 T 13-09-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 THL1_RS10865 452701a1635c9721158d3d2b37d77303 238 PANTHER PTHR11921:SF29 6 235 1.5E-131 T 13-09-2016 THL1_RS10865 452701a1635c9721158d3d2b37d77303 238 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 9 230 3.0E-83 T 13-09-2016 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 THL1_RS10865 452701a1635c9721158d3d2b37d77303 238 PANTHER PTHR11921 6 235 1.5E-131 T 13-09-2016 THL1_RS10865 452701a1635c9721158d3d2b37d77303 238 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 6 111 2.5E-30 T 13-09-2016 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 THL1_RS10865 452701a1635c9721158d3d2b37d77303 238 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 149 160 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS10865 452701a1635c9721158d3d2b37d77303 238 Gene3D G3DSA:3.10.20.30 3 107 9.8E-36 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS10865 452701a1635c9721158d3d2b37d77303 238 Gene3D G3DSA:1.10.1060.10 109 236 4.4E-47 T 13-09-2016 THL1_RS10865 452701a1635c9721158d3d2b37d77303 238 SUPERFAMILY SSF54292 4 107 4.66E-26 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS09045 1ba284bc60474012498001b7cfa6378a 491 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 4 474 1.0E-150 T 13-09-2016 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UniPathway: UPA00148 THL1_RS09045 1ba284bc60474012498001b7cfa6378a 491 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 250 434 4.5E-59 T 13-09-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 THL1_RS09045 1ba284bc60474012498001b7cfa6378a 491 SUPERFAMILY SSF52540 1 235 7.31E-59 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09045 1ba284bc60474012498001b7cfa6378a 491 PANTHER PTHR21343 1 481 6.2E-231 T 13-09-2016 THL1_RS09045 1ba284bc60474012498001b7cfa6378a 491 PANTHER PTHR21343:SF1 1 481 6.2E-231 T 13-09-2016 THL1_RS09045 1ba284bc60474012498001b7cfa6378a 491 Gene3D G3DSA:3.40.50.300 1 235 5.8E-52 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09045 1ba284bc60474012498001b7cfa6378a 491 SUPERFAMILY SSF52317 251 443 5.69E-40 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS09045 1ba284bc60474012498001b7cfa6378a 491 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 484 218.368 T 13-09-2016 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 UniPathway: UPA00148 THL1_RS09045 1ba284bc60474012498001b7cfa6378a 491 Gene3D G3DSA:3.40.50.880 250 443 1.0E-29 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS09045 1ba284bc60474012498001b7cfa6378a 491 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 229 1.8E-28 T 13-09-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 185 3.0E-32 T 13-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 Pfam PF14492 Elongation Factor G, domain II 414 488 1.3E-35 T 13-09-2016 IPR009022 Elongation factor G, III-V domain THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-09-2016 IPR031157 Tr-type G domain, conserved site THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 Hamap MF_00054_B Elongation factor G [fusA]. 6 708 107.908 T 13-09-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 PANTHER PTHR23115:SF66 313 708 0.0 T 13-09-2016 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 PANTHER PTHR23115:SF66 261 289 0.0 T 13-09-2016 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 PANTHER PTHR23115 3 184 0.0 T 13-09-2016 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 PANTHER PTHR23115 261 289 0.0 T 13-09-2016 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 PRINTS PR00315 GTP-binding elongation factor signature 85 95 6.7E-17 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 PRINTS PR00315 GTP-binding elongation factor signature 137 146 6.7E-17 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 PRINTS PR00315 GTP-binding elongation factor signature 58 66 6.7E-17 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 PRINTS PR00315 GTP-binding elongation factor signature 101 112 6.7E-17 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 PRINTS PR00315 GTP-binding elongation factor signature 12 25 6.7E-17 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 SUPERFAMILY SSF54211 489 615 7.33E-36 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 SUPERFAMILY SSF54980 620 706 3.6E-29 T 13-09-2016 IPR009022 Elongation factor G, III-V domain THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 Pfam PF00679 Elongation factor G C-terminus 618 702 1.7E-30 T 13-09-2016 IPR000640 Translation elongation factor EFG, V domain THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 Pfam PF03144 Elongation factor Tu domain 2 334 401 2.7E-17 T 13-09-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 Gene3D G3DSA:3.30.230.10 494 615 4.4E-42 T 13-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 SUPERFAMILY SSF54980 414 491 1.04E-25 T 13-09-2016 IPR009022 Elongation factor G, III-V domain THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 Gene3D G3DSA:2.40.30.10 315 415 1.3E-38 T 13-09-2016 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 Pfam PF00009 Elongation factor Tu GTP binding domain 9 287 2.4E-65 T 13-09-2016 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 Gene3D G3DSA:3.30.70.870 416 490 2.3E-40 T 13-09-2016 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 Gene3D G3DSA:3.40.50.300 6 293 2.1E-101 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 Gene3D G3DSA:3.30.70.240 616 701 1.3E-31 T 13-09-2016 IPR000640 Translation elongation factor EFG, V domain THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 SMART SM00838 617 704 2.0E-54 T 13-09-2016 IPR000640 Translation elongation factor EFG, V domain THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 SUPERFAMILY SSF52540 6 287 7.06E-104 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 SMART SM00889 490 615 1.9E-64 T 13-09-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 SUPERFAMILY SSF50447 271 414 1.02E-34 T 13-09-2016 IPR009000 Translation protein, beta-barrel domain THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 PANTHER PTHR23115:SF66 3 184 0.0 T 13-09-2016 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 PANTHER PTHR23115 313 708 0.0 T 13-09-2016 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 TIGRFAM TIGR00484 EF-G: translation elongation factor G 2 708 0.0 T 13-09-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 THL1_RS03510 b4b4d65438ef4d8ded11c3ae1e35996e 709 Pfam PF03764 Elongation factor G, domain IV 489 614 1.1E-40 T 13-09-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THL1_RS06440 0cf9e40fa7a86921b517b0b5193da6ac 141 Gene3D G3DSA:3.10.580.10 6 127 1.2E-31 T 13-09-2016 THL1_RS06440 0cf9e40fa7a86921b517b0b5193da6ac 141 SUPERFAMILY SSF54631 2 127 3.54E-34 T 13-09-2016 THL1_RS06440 0cf9e40fa7a86921b517b0b5193da6ac 141 PANTHER PTHR11911 1 137 4.1E-31 T 13-09-2016 THL1_RS06440 0cf9e40fa7a86921b517b0b5193da6ac 141 Pfam PF00571 CBS domain 7 62 7.6E-13 T 13-09-2016 IPR000644 CBS domain THL1_RS06440 0cf9e40fa7a86921b517b0b5193da6ac 141 Pfam PF00571 CBS domain 74 128 6.7E-13 T 13-09-2016 IPR000644 CBS domain THL1_RS06440 0cf9e40fa7a86921b517b0b5193da6ac 141 SMART SM00116 81 128 2.1E-8 T 13-09-2016 IPR000644 CBS domain THL1_RS06440 0cf9e40fa7a86921b517b0b5193da6ac 141 SMART SM00116 14 62 4.5E-9 T 13-09-2016 IPR000644 CBS domain THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 SMART SM00732 323 422 4.2E-38 T 13-09-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 Gene3D G3DSA:1.10.150.310 497 628 6.6E-46 T 13-09-2016 IPR023097 Tex RuvX-like domain THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 SUPERFAMILY SSF47781 558 630 3.56E-20 T 13-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 Pfam PF09371 Tex-like protein N-terminal domain 8 190 1.4E-65 T 13-09-2016 IPR018974 Tex-like protein, N-terminal THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 Pfam PF00575 S1 RNA binding domain 648 718 3.8E-20 T 13-09-2016 IPR003029 S1 domain GO:0003676 THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 SUPERFAMILY SSF50249 636 722 6.64E-25 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 Gene3D G3DSA:1.10.3500.10 449 496 3.3E-100 T 13-09-2016 IPR023323 Tex-like domain THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 Gene3D G3DSA:1.10.3500.10 109 319 3.3E-100 T 13-09-2016 IPR023323 Tex-like domain THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 Pfam PF12836 Helix-hairpin-helix motif 489 553 1.4E-28 T 13-09-2016 THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 SUPERFAMILY SSF53098 319 467 1.97E-53 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 SUPERFAMILY SSF47781 468 554 3.34E-28 T 13-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 PANTHER PTHR10724:SF1 1 741 0.0 T 13-09-2016 THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 Pfam PF16921 Tex protein YqgF-like domain 324 449 3.8E-53 T 13-09-2016 IPR032639 Tex protein, YqgF-like domain THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 Gene3D G3DSA:1.10.10.650 2 108 3.9E-47 T 13-09-2016 IPR023319 Tex-like protein, HTH domain THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 SMART SM00316 647 718 4.4E-24 T 13-09-2016 IPR022967 RNA-binding domain, S1 THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 PANTHER PTHR10724 1 741 0.0 T 13-09-2016 THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 SUPERFAMILY SSF158832 2 318 4.05E-119 T 13-09-2016 THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 Gene3D G3DSA:2.40.50.140 632 720 1.2E-28 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS27145 73096a26f80384b6e9244caa93189fe4 771 Gene3D G3DSA:3.30.420.140 324 448 1.5E-52 T 13-09-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 THL1_RS27745 9f0170f60e4b7c028667105a259b086c 190 Pfam PF00156 Phosphoribosyl transferase domain 32 157 6.6E-7 T 13-09-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 THL1_RS27745 9f0170f60e4b7c028667105a259b086c 190 PANTHER PTHR11776 2 188 8.3E-85 T 13-09-2016 THL1_RS27745 9f0170f60e4b7c028667105a259b086c 190 PANTHER PTHR11776:SF1 2 188 8.3E-85 T 13-09-2016 THL1_RS27745 9f0170f60e4b7c028667105a259b086c 190 SUPERFAMILY SSF53271 2 189 1.12E-45 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS27745 9f0170f60e4b7c028667105a259b086c 190 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 41.14 T 13-09-2016 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22|UniPathway: UPA00602 THL1_RS27745 9f0170f60e4b7c028667105a259b086c 190 Gene3D G3DSA:3.40.50.2020 2 188 2.3E-63 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS27745 9f0170f60e4b7c028667105a259b086c 190 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 2 190 2.1E-85 T 13-09-2016 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22|UniPathway: UPA00602 THL1_RS12410 53346c63ef81cb8a4532930fe5b4d484 208 PANTHER PTHR35869 1 208 1.7E-54 T 13-09-2016 THL1_RS12410 53346c63ef81cb8a4532930fe5b4d484 208 Gene3D G3DSA:2.50.20.10 27 207 5.1E-57 T 13-09-2016 THL1_RS12410 53346c63ef81cb8a4532930fe5b4d484 208 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 36 198 6.5E-56 T 13-09-2016 IPR004564 Outer membrane lipoprotein carrier protein LolA-like THL1_RS12410 53346c63ef81cb8a4532930fe5b4d484 208 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 6 205 1.2E-34 T 13-09-2016 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 THL1_RS12410 53346c63ef81cb8a4532930fe5b4d484 208 SUPERFAMILY SSF89392 27 207 3.88E-53 T 13-09-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX THL1_RS12410 53346c63ef81cb8a4532930fe5b4d484 208 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 7 208 30.865 T 13-09-2016 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 THL1_RS17100 a6968b41721081c53aede370e48356c4 342 Pfam PF13416 Bacterial extracellular solute-binding protein 26 291 1.4E-20 T 13-09-2016 THL1_RS17100 a6968b41721081c53aede370e48356c4 342 PANTHER PTHR30222:SF5 9 336 3.8E-60 T 13-09-2016 THL1_RS17100 a6968b41721081c53aede370e48356c4 342 PIRSF PIRSF019574 2 339 9.3E-76 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS17100 a6968b41721081c53aede370e48356c4 342 Gene3D G3DSA:3.40.190.10 204 262 1.0E-6 T 13-09-2016 THL1_RS17100 a6968b41721081c53aede370e48356c4 342 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 241 260 2.1E-24 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS17100 a6968b41721081c53aede370e48356c4 342 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 138 152 2.1E-24 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS17100 a6968b41721081c53aede370e48356c4 342 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 161 180 2.1E-24 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS17100 a6968b41721081c53aede370e48356c4 342 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 17 33 2.1E-24 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS17100 a6968b41721081c53aede370e48356c4 342 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 108 124 2.1E-24 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS17100 a6968b41721081c53aede370e48356c4 342 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 75 88 2.1E-24 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS17100 a6968b41721081c53aede370e48356c4 342 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 33 54 2.1E-24 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS17100 a6968b41721081c53aede370e48356c4 342 Gene3D G3DSA:3.40.190.10 263 295 4.4E-40 T 13-09-2016 THL1_RS17100 a6968b41721081c53aede370e48356c4 342 Gene3D G3DSA:3.40.190.10 11 117 4.4E-40 T 13-09-2016 THL1_RS17100 a6968b41721081c53aede370e48356c4 342 PANTHER PTHR30222 9 336 3.8E-60 T 13-09-2016 THL1_RS17100 a6968b41721081c53aede370e48356c4 342 SUPERFAMILY SSF53850 12 335 5.44E-55 T 13-09-2016 THL1_RS12650 8cfd8d5c809321c6e42a151968b9ed93 536 SMART SM00304 264 316 51.0 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS12650 8cfd8d5c809321c6e42a151968b9ed93 536 SMART SM00304 211 263 5.2E-11 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS12650 8cfd8d5c809321c6e42a151968b9ed93 536 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 336 534 2.3E-44 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS12650 8cfd8d5c809321c6e42a151968b9ed93 536 SUPERFAMILY SSF58104 231 536 2.75E-71 T 13-09-2016 THL1_RS12650 8cfd8d5c809321c6e42a151968b9ed93 536 Pfam PF00672 HAMP domain 192 260 2.3E-17 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS12650 8cfd8d5c809321c6e42a151968b9ed93 536 PANTHER PTHR32089 185 536 9.8E-116 T 13-09-2016 THL1_RS12650 8cfd8d5c809321c6e42a151968b9ed93 536 PANTHER PTHR32089 61 143 9.8E-116 T 13-09-2016 THL1_RS12650 8cfd8d5c809321c6e42a151968b9ed93 536 Gene3D G3DSA:1.10.287.950 292 505 2.1E-58 T 13-09-2016 THL1_RS12650 8cfd8d5c809321c6e42a151968b9ed93 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 376 403 3.9E-23 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS12650 8cfd8d5c809321c6e42a151968b9ed93 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 187 207 3.9E-23 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS12650 8cfd8d5c809321c6e42a151968b9ed93 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 6 31 3.9E-23 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS12650 8cfd8d5c809321c6e42a151968b9ed93 536 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 405 434 3.9E-23 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS12650 8cfd8d5c809321c6e42a151968b9ed93 536 Pfam PF12729 Four helix bundle sensory module for signal transduction 6 182 3.8E-14 T 13-09-2016 IPR024478 4HB MCP domain THL1_RS12650 8cfd8d5c809321c6e42a151968b9ed93 536 SMART SM00283 278 535 5.4E-72 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS09420 26952b5ec3e94fd17cf4026b1d9ab0d6 260 PIRSF PIRSF006241 1 259 2.4E-94 T 13-09-2016 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 THL1_RS09420 26952b5ec3e94fd17cf4026b1d9ab0d6 260 Pfam PF01261 Xylose isomerase-like TIM barrel 21 219 1.7E-31 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS09420 26952b5ec3e94fd17cf4026b1d9ab0d6 260 PANTHER PTHR12110 1 255 2.7E-103 T 13-09-2016 THL1_RS09420 26952b5ec3e94fd17cf4026b1d9ab0d6 260 TIGRFAM TIGR03234 OH-pyruv-isom: hydroxypyruvate isomerase 2 255 9.1E-124 T 13-09-2016 IPR017643 Hydroxypyruvate isomerase KEGG: 00630+5.3.1.22 THL1_RS09420 26952b5ec3e94fd17cf4026b1d9ab0d6 260 Gene3D G3DSA:3.20.20.150 1 255 4.5E-92 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS09420 26952b5ec3e94fd17cf4026b1d9ab0d6 260 PANTHER PTHR12110:SF3 1 255 2.7E-103 T 13-09-2016 THL1_RS09420 26952b5ec3e94fd17cf4026b1d9ab0d6 260 SUPERFAMILY SSF51658 1 256 7.59E-86 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS25825 7590f562c8e42be5bcb5acb36521418c 644 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 451 642 3.6E-42 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS25825 7590f562c8e42be5bcb5acb36521418c 644 SUPERFAMILY SSF58104 335 643 5.23E-61 T 13-09-2016 THL1_RS25825 7590f562c8e42be5bcb5acb36521418c 644 SMART SM00283 382 643 2.4E-49 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS25825 7590f562c8e42be5bcb5acb36521418c 644 SMART SM00304 313 367 2.3E-11 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS25825 7590f562c8e42be5bcb5acb36521418c 644 Pfam PF00672 HAMP domain 295 363 1.8E-13 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS25825 7590f562c8e42be5bcb5acb36521418c 644 PANTHER PTHR32089 287 644 3.5E-83 T 13-09-2016 THL1_RS25825 7590f562c8e42be5bcb5acb36521418c 644 PANTHER PTHR32089 197 224 3.5E-83 T 13-09-2016 THL1_RS25825 7590f562c8e42be5bcb5acb36521418c 644 Gene3D G3DSA:1.10.287.950 397 608 1.5E-45 T 13-09-2016 THL1_RS19055 4910a6b69d33f04adfe5784e1238faf5 265 Gene3D G3DSA:3.40.50.720 9 226 7.4E-58 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS19055 4910a6b69d33f04adfe5784e1238faf5 265 PANTHER PTHR24322:SF468 12 140 1.6E-46 T 13-09-2016 THL1_RS19055 4910a6b69d33f04adfe5784e1238faf5 265 PANTHER PTHR24322:SF468 156 188 1.6E-46 T 13-09-2016 THL1_RS19055 4910a6b69d33f04adfe5784e1238faf5 265 SUPERFAMILY SSF51735 6 230 3.86E-58 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS19055 4910a6b69d33f04adfe5784e1238faf5 265 Pfam PF00106 short chain dehydrogenase 9 197 2.7E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19055 4910a6b69d33f04adfe5784e1238faf5 265 PIRSF PIRSF000126 1 265 9.9E-69 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19055 4910a6b69d33f04adfe5784e1238faf5 265 PANTHER PTHR24322 12 140 1.6E-46 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19055 4910a6b69d33f04adfe5784e1238faf5 265 PANTHER PTHR24322 156 188 1.6E-46 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19055 4910a6b69d33f04adfe5784e1238faf5 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.2E-9 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19055 4910a6b69d33f04adfe5784e1238faf5 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.2E-9 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19055 4910a6b69d33f04adfe5784e1238faf5 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.2E-9 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19055 4910a6b69d33f04adfe5784e1238faf5 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.6E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19055 4910a6b69d33f04adfe5784e1238faf5 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.6E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19055 4910a6b69d33f04adfe5784e1238faf5 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.6E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19055 4910a6b69d33f04adfe5784e1238faf5 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 4.6E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19055 4910a6b69d33f04adfe5784e1238faf5 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.6E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS01085 b50a20589ae62c46b48e88a8e383a666 291 Gene3D G3DSA:3.40.50.10490 111 272 6.5E-9 T 13-09-2016 THL1_RS01085 b50a20589ae62c46b48e88a8e383a666 291 Gene3D G3DSA:1.10.10.10 2 78 2.2E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS01085 b50a20589ae62c46b48e88a8e383a666 291 SUPERFAMILY SSF53697 106 270 6.67E-10 T 13-09-2016 THL1_RS01085 b50a20589ae62c46b48e88a8e383a666 291 Pfam PF01418 Helix-turn-helix domain, rpiR family 5 76 5.9E-13 T 13-09-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 THL1_RS01085 b50a20589ae62c46b48e88a8e383a666 291 PANTHER PTHR30514 3 256 1.8E-16 T 13-09-2016 THL1_RS01085 b50a20589ae62c46b48e88a8e383a666 291 PANTHER PTHR30514:SF3 3 256 1.8E-16 T 13-09-2016 THL1_RS01085 b50a20589ae62c46b48e88a8e383a666 291 SUPERFAMILY SSF46689 3 79 6.27E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01085 b50a20589ae62c46b48e88a8e383a666 291 Pfam PF01380 SIS domain 131 255 3.6E-6 T 13-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 THL1_RS00335 9359006de20cc00fa20611b3dff702d5 166 PANTHER PTHR33202 7 165 1.2E-70 T 13-09-2016 THL1_RS00335 9359006de20cc00fa20611b3dff702d5 166 PANTHER PTHR33202:SF6 7 165 1.2E-70 T 13-09-2016 THL1_RS00335 9359006de20cc00fa20611b3dff702d5 166 Gene3D G3DSA:1.10.10.10 28 97 1.1E-10 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00335 9359006de20cc00fa20611b3dff702d5 166 Pfam PF01475 Ferric uptake regulator family 36 155 4.5E-11 T 13-09-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 THL1_RS00335 9359006de20cc00fa20611b3dff702d5 166 SUPERFAMILY SSF46785 30 160 1.02E-29 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 Gene3D G3DSA:3.30.450.20 344 489 1.4E-31 T 13-09-2016 THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 Gene3D G3DSA:3.30.450.20 616 767 3.3E-21 T 13-09-2016 THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 PANTHER PTHR10799:SF710 671 924 5.1E-26 T 13-09-2016 THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 Gene3D G3DSA:3.30.450.20 490 615 8.5E-20 T 13-09-2016 THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 SMART SM00086 583 625 1.8E-4 T 13-09-2016 IPR001610 PAC motif THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 SMART SM00086 715 756 4.4 T 13-09-2016 IPR001610 PAC motif THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 SMART SM00086 440 483 2.2E-7 T 13-09-2016 IPR001610 PAC motif THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 Pfam PF03924 CHASE domain 90 272 8.2E-32 T 13-09-2016 IPR006189 CHASE domain THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 Pfam PF13426 PAS domain 508 624 6.4E-10 T 13-09-2016 IPR000014 PAS domain THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 SMART SM00091 365 433 0.027 T 13-09-2016 IPR000014 PAS domain THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 SMART SM00091 640 709 100.0 T 13-09-2016 IPR000014 PAS domain THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 SMART SM00091 495 563 0.0011 T 13-09-2016 IPR000014 PAS domain THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 SMART SM01079 86 274 1.7E-34 T 13-09-2016 IPR006189 CHASE domain THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 363 489 1.4E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 504 632 2.8E-15 T 13-09-2016 IPR000014 PAS domain THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 SMART SM00267 756 924 4.3E-61 T 13-09-2016 IPR000160 GGDEF domain THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 SUPERFAMILY SSF55785 508 633 6.46E-18 T 13-09-2016 IPR000014 PAS domain THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 SUPERFAMILY SSF55785 371 484 2.97E-18 T 13-09-2016 IPR000014 PAS domain THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 Pfam PF08447 PAS fold 665 746 7.6E-7 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 Pfam PF08447 PAS fold 388 476 2.7E-20 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 Gene3D G3DSA:3.30.70.270 769 924 1.3E-52 T 13-09-2016 THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 Pfam PF00990 Diguanylate cyclase, GGDEF domain 768 920 7.0E-44 T 13-09-2016 IPR000160 GGDEF domain THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 SUPERFAMILY SSF55785 622 754 5.12E-11 T 13-09-2016 IPR000014 PAS domain THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 PANTHER PTHR10799 671 924 5.1E-26 T 13-09-2016 THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 SUPERFAMILY SSF55073 772 923 4.63E-47 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS10360 ce96fec7e8a0a310489506626864f64d 925 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 764 924 8.4E-47 T 13-09-2016 IPR000160 GGDEF domain THL1_RS03195 cc708a44082be37f070889a210a6f777 522 SUPERFAMILY SSF55103 246 516 3.92E-52 T 13-09-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 THL1_RS03195 cc708a44082be37f070889a210a6f777 522 Gene3D G3DSA:1.10.45.10 477 520 1.1E-18 T 13-09-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 THL1_RS03195 cc708a44082be37f070889a210a6f777 522 Gene3D G3DSA:3.30.43.10 6 115 4.7E-34 T 13-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 THL1_RS03195 cc708a44082be37f070889a210a6f777 522 PANTHER PTHR11748:SF92 10 513 3.0E-76 T 13-09-2016 THL1_RS03195 cc708a44082be37f070889a210a6f777 522 Gene3D G3DSA:3.40.462.10 246 476 3.5E-93 T 13-09-2016 IPR016170 Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain KEGG: 00908+1.5.99.12 THL1_RS03195 cc708a44082be37f070889a210a6f777 522 Pfam PF01565 FAD binding domain 59 199 5.2E-27 T 13-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THL1_RS03195 cc708a44082be37f070889a210a6f777 522 PANTHER PTHR11748 10 513 3.0E-76 T 13-09-2016 THL1_RS03195 cc708a44082be37f070889a210a6f777 522 Gene3D G3DSA:3.30.465.10 116 243 4.4E-36 T 13-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THL1_RS03195 cc708a44082be37f070889a210a6f777 522 SUPERFAMILY SSF56176 12 243 3.46E-58 T 13-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THL1_RS03195 cc708a44082be37f070889a210a6f777 522 Pfam PF02913 FAD linked oxidases, C-terminal domain 331 513 4.6E-12 T 13-09-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 THL1_RS21470 652e469a46e2e3a13bebb9c4354f5422 649 SMART SM00304 173 225 5.8E-6 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS21470 652e469a46e2e3a13bebb9c4354f5422 649 Pfam PF00563 EAL domain 419 645 1.6E-54 T 13-09-2016 IPR001633 EAL domain THL1_RS21470 652e469a46e2e3a13bebb9c4354f5422 649 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 236 392 1.9E-13 T 13-09-2016 IPR000160 GGDEF domain THL1_RS21470 652e469a46e2e3a13bebb9c4354f5422 649 Pfam PF00990 Diguanylate cyclase, GGDEF domain 238 392 1.7E-22 T 13-09-2016 IPR000160 GGDEF domain THL1_RS21470 652e469a46e2e3a13bebb9c4354f5422 649 Pfam PF16448 LapD/MoxY periplasmic domain 23 147 1.9E-39 T 13-09-2016 IPR032244 LapD/MoxY, periplasmic domain THL1_RS21470 652e469a46e2e3a13bebb9c4354f5422 649 SUPERFAMILY SSF55073 243 396 2.51E-20 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS21470 652e469a46e2e3a13bebb9c4354f5422 649 SMART SM00267 227 399 1.0E-22 T 13-09-2016 IPR000160 GGDEF domain THL1_RS21470 652e469a46e2e3a13bebb9c4354f5422 649 PANTHER PTHR33121:SF10 410 647 1.1E-36 T 13-09-2016 THL1_RS21470 652e469a46e2e3a13bebb9c4354f5422 649 Gene3D G3DSA:3.20.20.450 414 647 1.9E-48 T 13-09-2016 IPR001633 EAL domain THL1_RS21470 652e469a46e2e3a13bebb9c4354f5422 649 PANTHER PTHR33121 410 647 1.1E-36 T 13-09-2016 THL1_RS21470 652e469a46e2e3a13bebb9c4354f5422 649 Pfam PF00672 HAMP domain 154 221 4.1E-9 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS21470 652e469a46e2e3a13bebb9c4354f5422 649 SUPERFAMILY SSF141868 417 648 2.88E-52 T 13-09-2016 IPR001633 EAL domain THL1_RS21470 652e469a46e2e3a13bebb9c4354f5422 649 SMART SM00052 410 647 3.0E-25 T 13-09-2016 IPR001633 EAL domain THL1_RS21470 652e469a46e2e3a13bebb9c4354f5422 649 Gene3D G3DSA:3.30.70.270 239 398 1.4E-24 T 13-09-2016 THL1_RS15540 857006d275b11592b708b49a3874106c 454 PANTHER PTHR13847:SF196 13 431 3.4E-74 T 13-09-2016 THL1_RS15540 857006d275b11592b708b49a3874106c 454 Gene3D G3DSA:3.50.50.60 25 126 1.3E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS15540 857006d275b11592b708b49a3874106c 454 Gene3D G3DSA:3.50.50.60 364 413 1.3E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS15540 857006d275b11592b708b49a3874106c 454 Gene3D G3DSA:3.50.50.60 181 261 1.3E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS15540 857006d275b11592b708b49a3874106c 454 PANTHER PTHR13847 13 431 3.4E-74 T 13-09-2016 THL1_RS15540 857006d275b11592b708b49a3874106c 454 SUPERFAMILY SSF51905 375 411 1.14E-39 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS15540 857006d275b11592b708b49a3874106c 454 SUPERFAMILY SSF51905 34 262 1.14E-39 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS15540 857006d275b11592b708b49a3874106c 454 Pfam PF01266 FAD dependent oxidoreductase 35 402 1.6E-49 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS20530 516d399d3b012d18a1c09cacf2f101a2 217 Gene3D G3DSA:1.20.1290.10 9 215 4.2E-47 T 13-09-2016 IPR029032 AhpD-like THL1_RS20530 516d399d3b012d18a1c09cacf2f101a2 217 SUPERFAMILY SSF69118 8 215 4.8E-30 T 13-09-2016 IPR029032 AhpD-like THL1_RS14040 a763e38c42e212d9e0a03f120671e32e 363 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 39 356 1.1E-108 T 13-09-2016 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 THL1_RS14040 a763e38c42e212d9e0a03f120671e32e 363 Gene3D G3DSA:3.40.50.300 5 242 1.0E-77 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14040 a763e38c42e212d9e0a03f120671e32e 363 SUPERFAMILY SSF52540 9 246 2.05E-82 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14040 a763e38c42e212d9e0a03f120671e32e 363 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS14040 a763e38c42e212d9e0a03f120671e32e 363 Pfam PF08402 TOBE domain 281 360 6.6E-10 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS14040 a763e38c42e212d9e0a03f120671e32e 363 PANTHER PTHR24220:SF402 10 247 2.0E-118 T 13-09-2016 THL1_RS14040 a763e38c42e212d9e0a03f120671e32e 363 SMART SM00382 33 216 2.6E-17 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS14040 a763e38c42e212d9e0a03f120671e32e 363 Pfam PF00005 ABC transporter 24 166 4.2E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS14040 a763e38c42e212d9e0a03f120671e32e 363 PANTHER PTHR24220 10 247 2.0E-118 T 13-09-2016 THL1_RS14040 a763e38c42e212d9e0a03f120671e32e 363 SUPERFAMILY SSF50331 242 360 4.7E-11 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS19490 9cb28bddf70fac84ba9b969b78371fd1 362 SUPERFAMILY SSF52738 176 361 1.14E-63 T 13-09-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS19490 9cb28bddf70fac84ba9b969b78371fd1 362 Gene3D G3DSA:3.40.50.180 174 361 2.0E-72 T 13-09-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS19490 9cb28bddf70fac84ba9b969b78371fd1 362 SUPERFAMILY SSF52172 3 109 1.12E-27 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS19490 9cb28bddf70fac84ba9b969b78371fd1 362 PIRSF PIRSF000876 1 362 3.0E-134 T 13-09-2016 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS19490 9cb28bddf70fac84ba9b969b78371fd1 362 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 3 362 39.733 T 13-09-2016 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS19490 9cb28bddf70fac84ba9b969b78371fd1 362 PANTHER PTHR24421 1 357 3.3E-166 T 13-09-2016 THL1_RS19490 9cb28bddf70fac84ba9b969b78371fd1 362 Pfam PF00072 Response regulator receiver domain 5 109 2.8E-22 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS19490 9cb28bddf70fac84ba9b969b78371fd1 362 SMART SM00448 3 118 1.2E-24 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS19490 9cb28bddf70fac84ba9b969b78371fd1 362 Pfam PF01339 CheB methylesterase 181 357 2.6E-57 T 13-09-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS19490 9cb28bddf70fac84ba9b969b78371fd1 362 Gene3D G3DSA:3.40.50.2300 3 128 1.2E-28 T 13-09-2016 THL1_RS19490 9cb28bddf70fac84ba9b969b78371fd1 362 PANTHER PTHR24421:SF16 1 357 3.3E-166 T 13-09-2016 THL1_RS27540 477f2eff544e92aede428e344beb9dbb 87 PANTHER PTHR38040:SF1 2 84 5.8E-30 T 13-09-2016 THL1_RS27540 477f2eff544e92aede428e344beb9dbb 87 PANTHER PTHR38040 2 84 5.8E-30 T 13-09-2016 THL1_RS27540 477f2eff544e92aede428e344beb9dbb 87 Pfam PF04380 Membrane fusogenic activity 5 79 2.1E-23 T 13-09-2016 IPR007475 Membrane fusogenic activity THL1_RS17920 4a0bae99ae03e29b319ae5ae88d05214 474 Pfam PF08668 HDOD domain 13 197 1.5E-36 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS17920 4a0bae99ae03e29b319ae5ae88d05214 474 SUPERFAMILY SSF55781 307 468 1.26E-11 T 13-09-2016 IPR029016 GAF domain-like THL1_RS17920 4a0bae99ae03e29b319ae5ae88d05214 474 SUPERFAMILY SSF109604 8 263 3.06E-47 T 13-09-2016 THL1_RS17920 4a0bae99ae03e29b319ae5ae88d05214 474 Gene3D G3DSA:1.10.3150.10 11 263 1.7E-51 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS17920 4a0bae99ae03e29b319ae5ae88d05214 474 Pfam PF13492 GAF domain 325 464 7.7E-7 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS17920 4a0bae99ae03e29b319ae5ae88d05214 474 Gene3D G3DSA:3.30.450.40 306 468 2.2E-12 T 13-09-2016 IPR029016 GAF domain-like THL1_RS17920 4a0bae99ae03e29b319ae5ae88d05214 474 PANTHER PTHR33525 9 201 6.9E-35 T 13-09-2016 THL1_RS17920 4a0bae99ae03e29b319ae5ae88d05214 474 PANTHER PTHR33525:SF3 9 201 6.9E-35 T 13-09-2016 THL1_RS09920 89ab9197713f2514db08970800e4022a 519 PANTHER PTHR23501 14 519 1.6E-280 T 13-09-2016 THL1_RS09920 89ab9197713f2514db08970800e4022a 519 Gene3D G3DSA:1.20.1250.20 22 197 9.2E-22 T 13-09-2016 THL1_RS09920 89ab9197713f2514db08970800e4022a 519 Gene3D G3DSA:1.20.1250.20 272 427 3.8E-13 T 13-09-2016 THL1_RS09920 89ab9197713f2514db08970800e4022a 519 Pfam PF07690 Major Facilitator Superfamily 25 418 7.0E-43 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS09920 89ab9197713f2514db08970800e4022a 519 PANTHER PTHR23501:SF51 14 519 1.6E-280 T 13-09-2016 THL1_RS09920 89ab9197713f2514db08970800e4022a 519 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 20 498 4.2E-118 T 13-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 THL1_RS09920 89ab9197713f2514db08970800e4022a 519 SUPERFAMILY SSF103473 12 202 1.16E-56 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS09920 89ab9197713f2514db08970800e4022a 519 SUPERFAMILY SSF103473 257 428 1.16E-56 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS09920 89ab9197713f2514db08970800e4022a 519 SUPERFAMILY SSF103473 480 504 1.16E-56 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS22365 3672387d587c27d8ee12dfd075e29988 182 PANTHER PTHR30529:SF3 2 181 2.3E-86 T 13-09-2016 THL1_RS22365 3672387d587c27d8ee12dfd075e29988 182 Pfam PF01292 Prokaryotic cytochrome b561 9 180 1.8E-25 T 13-09-2016 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THL1_RS22365 3672387d587c27d8ee12dfd075e29988 182 PANTHER PTHR30529 2 181 2.3E-86 T 13-09-2016 THL1_RS22365 3672387d587c27d8ee12dfd075e29988 182 SUPERFAMILY SSF81342 5 181 1.41E-35 T 13-09-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 THL1_RS27165 02a3c2cc3a64a6231be2d18bce2390df 385 PANTHER PTHR11014 6 382 5.8E-189 T 13-09-2016 THL1_RS27165 02a3c2cc3a64a6231be2d18bce2390df 385 SUPERFAMILY SSF53187 5 176 3.71E-56 T 13-09-2016 THL1_RS27165 02a3c2cc3a64a6231be2d18bce2390df 385 SUPERFAMILY SSF53187 301 378 3.71E-56 T 13-09-2016 THL1_RS27165 02a3c2cc3a64a6231be2d18bce2390df 385 Gene3D G3DSA:3.30.70.360 186 288 2.8E-24 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS27165 02a3c2cc3a64a6231be2d18bce2390df 385 Pfam PF01546 Peptidase family M20/M25/M40 73 375 1.2E-30 T 13-09-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 THL1_RS27165 02a3c2cc3a64a6231be2d18bce2390df 385 SUPERFAMILY SSF55031 177 292 9.12E-22 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS27165 02a3c2cc3a64a6231be2d18bce2390df 385 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 10 374 1.7E-115 T 13-09-2016 IPR010169 Acetylornithine deacetylase (ArgE) GO:0005737|GO:0006526|GO:0008270|GO:0008777|GO:0050897 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154|UniPathway: UPA00068 THL1_RS27165 02a3c2cc3a64a6231be2d18bce2390df 385 Pfam PF07687 Peptidase dimerisation domain 175 285 5.8E-24 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS27165 02a3c2cc3a64a6231be2d18bce2390df 385 PANTHER PTHR11014:SF75 6 382 5.8E-189 T 13-09-2016 THL1_RS27165 02a3c2cc3a64a6231be2d18bce2390df 385 Hamap MF_01108 Acetylornithine deacetylase [argE]. 1 379 51.309 T 13-09-2016 IPR010169 Acetylornithine deacetylase (ArgE) GO:0005737|GO:0006526|GO:0008270|GO:0008777|GO:0050897 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154|UniPathway: UPA00068 THL1_RS27165 02a3c2cc3a64a6231be2d18bce2390df 385 Gene3D G3DSA:3.40.630.10 6 185 7.5E-59 T 13-09-2016 THL1_RS27165 02a3c2cc3a64a6231be2d18bce2390df 385 Gene3D G3DSA:3.40.630.10 319 378 7.5E-59 T 13-09-2016 THL1_RS17370 743057cc7751a7ae04e0fbbdd9fea1dd 360 SUPERFAMILY SSF50331 240 358 6.03E-19 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS17370 743057cc7751a7ae04e0fbbdd9fea1dd 360 Pfam PF08402 TOBE domain 281 358 1.4E-14 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS17370 743057cc7751a7ae04e0fbbdd9fea1dd 360 Pfam PF00005 ABC transporter 23 165 8.1E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS17370 743057cc7751a7ae04e0fbbdd9fea1dd 360 SUPERFAMILY SSF52540 7 248 1.08E-84 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17370 743057cc7751a7ae04e0fbbdd9fea1dd 360 PANTHER PTHR24220 8 353 6.5E-164 T 13-09-2016 THL1_RS17370 743057cc7751a7ae04e0fbbdd9fea1dd 360 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 38 356 8.6E-114 T 13-09-2016 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 THL1_RS17370 743057cc7751a7ae04e0fbbdd9fea1dd 360 SMART SM00382 32 214 1.7E-11 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS17370 743057cc7751a7ae04e0fbbdd9fea1dd 360 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS17370 743057cc7751a7ae04e0fbbdd9fea1dd 360 Gene3D G3DSA:3.40.50.300 3 241 1.7E-77 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17370 743057cc7751a7ae04e0fbbdd9fea1dd 360 PANTHER PTHR24220:SF402 8 353 6.5E-164 T 13-09-2016 THL1_RS01795 957bcb2b235dbb4b6f98ccc86a244463 686 Gene3D G3DSA:3.50.50.60 477 633 1.3E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01795 957bcb2b235dbb4b6f98ccc86a244463 686 Gene3D G3DSA:3.50.50.60 375 463 1.2E-18 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01795 957bcb2b235dbb4b6f98ccc86a244463 686 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 392 414 5.0E-7 T 13-09-2016 THL1_RS01795 957bcb2b235dbb4b6f98ccc86a244463 686 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 609 623 5.0E-7 T 13-09-2016 THL1_RS01795 957bcb2b235dbb4b6f98ccc86a244463 686 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 660 667 5.0E-7 T 13-09-2016 THL1_RS01795 957bcb2b235dbb4b6f98ccc86a244463 686 Gene3D G3DSA:3.20.20.70 2 374 5.9E-107 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS01795 957bcb2b235dbb4b6f98ccc86a244463 686 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 6 343 5.3E-61 T 13-09-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 THL1_RS01795 957bcb2b235dbb4b6f98ccc86a244463 686 SUPERFAMILY SSF51905 380 683 8.29E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01795 957bcb2b235dbb4b6f98ccc86a244463 686 PANTHER PTHR22893 1 433 1.9E-195 T 13-09-2016 THL1_RS01795 957bcb2b235dbb4b6f98ccc86a244463 686 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 393 412 2.8E-5 T 13-09-2016 THL1_RS01795 957bcb2b235dbb4b6f98ccc86a244463 686 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 608 624 2.8E-5 T 13-09-2016 THL1_RS01795 957bcb2b235dbb4b6f98ccc86a244463 686 Pfam PF13450 NAD(P)-binding Rossmann-like domain 395 434 1.0E-9 T 13-09-2016 THL1_RS01795 957bcb2b235dbb4b6f98ccc86a244463 686 PANTHER PTHR22893:SF25 1 433 1.9E-195 T 13-09-2016 THL1_RS01795 957bcb2b235dbb4b6f98ccc86a244463 686 SUPERFAMILY SSF51395 4 370 2.26E-97 T 13-09-2016 THL1_RS11895 c5b0f20e07451b2d687d7c22c1f19712 222 PANTHER PTHR12151 53 158 2.0E-20 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS11895 c5b0f20e07451b2d687d7c22c1f19712 222 Gene3D G3DSA:3.40.30.10 15 203 4.9E-29 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS11895 c5b0f20e07451b2d687d7c22c1f19712 222 SUPERFAMILY SSF52833 46 201 8.96E-28 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS11895 c5b0f20e07451b2d687d7c22c1f19712 222 Pfam PF02630 SCO1/SenC 68 151 1.7E-9 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS07880 45682f9635ddc848b9927abb7c1084f6 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 1.1E-20 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS07880 45682f9635ddc848b9927abb7c1084f6 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 2.8E-11 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS07880 45682f9635ddc848b9927abb7c1084f6 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 2.8E-11 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS07880 45682f9635ddc848b9927abb7c1084f6 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 2.8E-11 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS07880 45682f9635ddc848b9927abb7c1084f6 296 Gene3D G3DSA:1.10.10.10 3 82 3.5E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07880 45682f9635ddc848b9927abb7c1084f6 296 Gene3D G3DSA:3.40.190.10 98 178 2.2E-22 T 13-09-2016 THL1_RS07880 45682f9635ddc848b9927abb7c1084f6 296 SUPERFAMILY SSF53850 94 294 1.63E-30 T 13-09-2016 THL1_RS07880 45682f9635ddc848b9927abb7c1084f6 296 SUPERFAMILY SSF46785 6 81 7.19E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07880 45682f9635ddc848b9927abb7c1084f6 296 Gene3D G3DSA:3.40.190.10 179 261 2.5E-19 T 13-09-2016 THL1_RS07880 45682f9635ddc848b9927abb7c1084f6 296 PANTHER PTHR30537:SF26 1 295 1.9E-90 T 13-09-2016 THL1_RS07880 45682f9635ddc848b9927abb7c1084f6 296 PANTHER PTHR30537 1 295 1.9E-90 T 13-09-2016 THL1_RS07880 45682f9635ddc848b9927abb7c1084f6 296 Pfam PF03466 LysR substrate binding domain 92 291 2.5E-27 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS27410 75401e9e4e2a1aa3641d6714800080af 360 ProDom PD032367 ALGINATE REGULATORY ALGR3 ALGP TRANSCRIPTION TRANSCRIPTIONAL DNA-BINDING ACTIVATOR KINASES KINASE 1 123 3.0E-31 T 13-09-2016 THL1_RS23480 f6c6b1d90c49cca8d9f8b2c5c9ceab7a 507 PANTHER PTHR34219:SF4 1 494 2.4E-180 T 13-09-2016 THL1_RS23480 f6c6b1d90c49cca8d9f8b2c5c9ceab7a 507 Pfam PF03929 PepSY-associated TM region 10 355 3.4E-54 T 13-09-2016 IPR005625 PepSY-associated TM protein THL1_RS23480 f6c6b1d90c49cca8d9f8b2c5c9ceab7a 507 PANTHER PTHR34219 1 494 2.4E-180 T 13-09-2016 THL1_RS16970 edde1983e0077a9e771282ab7dd705de 297 SUPERFAMILY SSF53850 93 296 5.85E-51 T 13-09-2016 THL1_RS16970 edde1983e0077a9e771282ab7dd705de 297 Gene3D G3DSA:3.40.190.10 179 264 1.1E-23 T 13-09-2016 THL1_RS16970 edde1983e0077a9e771282ab7dd705de 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 7.1E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS16970 edde1983e0077a9e771282ab7dd705de 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 7.1E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS16970 edde1983e0077a9e771282ab7dd705de 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 7.1E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS16970 edde1983e0077a9e771282ab7dd705de 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 64 3.0E-20 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS16970 edde1983e0077a9e771282ab7dd705de 297 SUPERFAMILY SSF46785 7 113 5.4E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS16970 edde1983e0077a9e771282ab7dd705de 297 Pfam PF03466 LysR substrate binding domain 91 295 3.6E-51 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS16970 edde1983e0077a9e771282ab7dd705de 297 Gene3D G3DSA:3.40.190.10 92 178 3.9E-24 T 13-09-2016 THL1_RS16970 edde1983e0077a9e771282ab7dd705de 297 Gene3D G3DSA:1.10.10.10 5 89 1.3E-26 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS16970 edde1983e0077a9e771282ab7dd705de 297 PANTHER PTHR30419 1 297 4.3E-115 T 13-09-2016 THL1_RS16970 edde1983e0077a9e771282ab7dd705de 297 PANTHER PTHR30419:SF0 1 297 4.3E-115 T 13-09-2016 THL1_RS10610 c47ff609ec6eb2a4af32d2bca5a8a806 391 PANTHER PTHR18919 3 391 1.3E-192 T 13-09-2016 THL1_RS10610 c47ff609ec6eb2a4af32d2bca5a8a806 391 SUPERFAMILY SSF53901 4 262 1.0E-78 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS10610 c47ff609ec6eb2a4af32d2bca5a8a806 391 TIGRFAM TIGR02445 fadA: acetyl-CoA C-acyltransferase FadA 7 391 2.8E-227 T 13-09-2016 IPR012805 Acetyl-CoA C-acyltransferase FadA GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS10610 c47ff609ec6eb2a4af32d2bca5a8a806 391 Gene3D G3DSA:3.40.47.10 7 130 7.9E-63 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS10610 c47ff609ec6eb2a4af32d2bca5a8a806 391 Gene3D G3DSA:3.40.47.10 188 271 7.9E-63 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS10610 c47ff609ec6eb2a4af32d2bca5a8a806 391 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 389 6.2E-134 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS10610 c47ff609ec6eb2a4af32d2bca5a8a806 391 Hamap MF_01620 3-ketoacyl-CoA thiolase [fadA]. 5 391 59.303 T 13-09-2016 IPR012805 Acetyl-CoA C-acyltransferase FadA GO:0003988|GO:0005737|GO:0006631|GO:0016042 KEGG: 00062+2.3.1.16|KEGG: 00071+2.3.1.16|KEGG: 00280+2.3.1.16|KEGG: 00281+2.3.1.16|KEGG: 00362+2.3.1.16|KEGG: 00592+2.3.1.16|KEGG: 00642+2.3.1.16|MetaCyc: PWY-5136|MetaCyc: PWY-6435|MetaCyc: PWY-6863|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-7094|MetaCyc: PWY-7288|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7339|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS10610 c47ff609ec6eb2a4af32d2bca5a8a806 391 SUPERFAMILY SSF53901 266 390 3.96E-42 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS10610 c47ff609ec6eb2a4af32d2bca5a8a806 391 Pfam PF00108 Thiolase, N-terminal domain 9 257 9.6E-84 T 13-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THL1_RS10610 c47ff609ec6eb2a4af32d2bca5a8a806 391 Pfam PF02803 Thiolase, C-terminal domain 266 390 1.2E-47 T 13-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THL1_RS10610 c47ff609ec6eb2a4af32d2bca5a8a806 391 PANTHER PTHR18919:SF69 3 391 1.3E-192 T 13-09-2016 THL1_RS10610 c47ff609ec6eb2a4af32d2bca5a8a806 391 Gene3D G3DSA:3.40.47.10 145 187 2.0E-56 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS10610 c47ff609ec6eb2a4af32d2bca5a8a806 391 Gene3D G3DSA:3.40.47.10 272 390 2.0E-56 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS10610 c47ff609ec6eb2a4af32d2bca5a8a806 391 PIRSF PIRSF000429 2 391 9.6E-134 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS10610 c47ff609ec6eb2a4af32d2bca5a8a806 391 ProSitePatterns PS00737 Thiolases signature 2. 337 353 - T 13-09-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 THL1_RS10610 c47ff609ec6eb2a4af32d2bca5a8a806 391 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 91 109 - T 13-09-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 THL1_RS01125 0a5e34cff370e56ae74670352a4f720a 270 Gene3D G3DSA:1.10.8.50 131 270 1.4E-46 T 13-09-2016 THL1_RS01125 0a5e34cff370e56ae74670352a4f720a 270 SUPERFAMILY SSF57716 218 269 1.57E-16 T 13-09-2016 THL1_RS01125 0a5e34cff370e56ae74670352a4f720a 270 SUPERFAMILY SSF81624 2 135 3.92E-41 T 13-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 THL1_RS01125 0a5e34cff370e56ae74670352a4f720a 270 PANTHER PTHR22993:SF15 1 270 5.5E-127 T 13-09-2016 THL1_RS01125 0a5e34cff370e56ae74670352a4f720a 270 Gene3D G3DSA:3.20.190.10 2 130 7.2E-39 T 13-09-2016 THL1_RS01125 0a5e34cff370e56ae74670352a4f720a 270 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 1.3E-32 T 13-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 THL1_RS01125 0a5e34cff370e56ae74670352a4f720a 270 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 130 219 3.7E-22 T 13-09-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 THL1_RS01125 0a5e34cff370e56ae74670352a4f720a 270 ProSitePatterns PS01242 Zinc finger FPG-type signature. 245 269 - T 13-09-2016 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 THL1_RS01125 0a5e34cff370e56ae74670352a4f720a 270 PANTHER PTHR22993 1 270 5.5E-127 T 13-09-2016 THL1_RS01125 0a5e34cff370e56ae74670352a4f720a 270 SUPERFAMILY SSF46946 131 222 3.27E-27 T 13-09-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 THL1_RS01125 0a5e34cff370e56ae74670352a4f720a 270 SMART SM01232 130 222 7.4E-45 T 13-09-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 THL1_RS01125 0a5e34cff370e56ae74670352a4f720a 270 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 269 1.9E-91 T 13-09-2016 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 THL1_RS01125 0a5e34cff370e56ae74670352a4f720a 270 SMART SM00898 2 116 2.2E-53 T 13-09-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 THL1_RS01125 0a5e34cff370e56ae74670352a4f720a 270 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 270 44.274 T 13-09-2016 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 THL1_RS01125 0a5e34cff370e56ae74670352a4f720a 270 Pfam PF06827 Zinc finger found in FPG and IleRS 242 269 9.0E-9 T 13-09-2016 IPR010663 Zinc finger, FPG/IleRS-type THL1_RS02910 d3967aa66151e7983d64847cc2d34056 130 PANTHER PTHR37936 1 130 6.9E-36 T 13-09-2016 THL1_RS02910 d3967aa66151e7983d64847cc2d34056 130 Pfam PF01527 Transposase 17 96 9.4E-28 T 13-09-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 THL1_RS02910 d3967aa66151e7983d64847cc2d34056 130 SUPERFAMILY SSF46689 19 112 1.65E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS02910 d3967aa66151e7983d64847cc2d34056 130 Gene3D G3DSA:1.10.10.60 25 110 7.1E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS07080 ba4e95d20250ba20fb340169b54b909f 382 SUPERFAMILY SSF53901 260 381 3.01E-42 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS07080 ba4e95d20250ba20fb340169b54b909f 382 SUPERFAMILY SSF53901 3 259 4.01E-61 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS07080 ba4e95d20250ba20fb340169b54b909f 382 Pfam PF00108 Thiolase, N-terminal domain 5 251 8.9E-52 T 13-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THL1_RS07080 ba4e95d20250ba20fb340169b54b909f 382 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 380 2.9E-118 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS07080 ba4e95d20250ba20fb340169b54b909f 382 Gene3D G3DSA:3.40.47.10 159 193 8.8E-56 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS07080 ba4e95d20250ba20fb340169b54b909f 382 Gene3D G3DSA:3.40.47.10 266 381 8.8E-56 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS07080 ba4e95d20250ba20fb340169b54b909f 382 PANTHER PTHR18919:SF71 1 382 3.8E-183 T 13-09-2016 THL1_RS07080 ba4e95d20250ba20fb340169b54b909f 382 ProSitePatterns PS00737 Thiolases signature 2. 328 344 - T 13-09-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 THL1_RS07080 ba4e95d20250ba20fb340169b54b909f 382 PIRSF PIRSF000429 1 382 2.5E-112 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS07080 ba4e95d20250ba20fb340169b54b909f 382 Pfam PF02803 Thiolase, C-terminal domain 260 381 5.3E-42 T 13-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THL1_RS07080 ba4e95d20250ba20fb340169b54b909f 382 PANTHER PTHR18919 1 382 3.8E-183 T 13-09-2016 THL1_RS07080 ba4e95d20250ba20fb340169b54b909f 382 Gene3D G3DSA:3.40.47.10 4 124 8.0E-55 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS07080 ba4e95d20250ba20fb340169b54b909f 382 Gene3D G3DSA:3.40.47.10 194 265 8.0E-55 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS05720 a840685487562052cc2a843df74286b4 303 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 149 1.0E-32 T 13-09-2016 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|UniPathway: UPA00028 THL1_RS05720 a840685487562052cc2a843df74286b4 303 Gene3D G3DSA:3.40.50.720 1 182 1.0E-39 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS05720 a840685487562052cc2a843df74286b4 303 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 174 293 1.3E-29 T 13-09-2016 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|UniPathway: UPA00028 THL1_RS05720 a840685487562052cc2a843df74286b4 303 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 294 1.5E-70 T 13-09-2016 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|UniPathway: UPA00028 THL1_RS05720 a840685487562052cc2a843df74286b4 303 PANTHER PTHR21708:SF24 1 293 9.3E-67 T 13-09-2016 THL1_RS05720 a840685487562052cc2a843df74286b4 303 PANTHER PTHR21708 1 293 9.3E-67 T 13-09-2016 THL1_RS05720 a840685487562052cc2a843df74286b4 303 Gene3D G3DSA:1.10.1040.10 183 293 3.1E-33 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS05720 a840685487562052cc2a843df74286b4 303 SUPERFAMILY SSF48179 174 293 3.4E-30 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS05720 a840685487562052cc2a843df74286b4 303 SUPERFAMILY SSF51735 1 162 6.89E-31 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07565 c756e4b5e59fa68bb3dec05bfe030b33 141 SUPERFAMILY SSF82784 1 140 2.22E-44 T 13-09-2016 IPR003718 OsmC/Ohr family THL1_RS07565 c756e4b5e59fa68bb3dec05bfe030b33 141 PANTHER PTHR33797:SF2 1 140 2.9E-69 T 13-09-2016 THL1_RS07565 c756e4b5e59fa68bb3dec05bfe030b33 141 Gene3D G3DSA:2.20.25.10 1 47 4.0E-22 T 13-09-2016 THL1_RS07565 c756e4b5e59fa68bb3dec05bfe030b33 141 PANTHER PTHR33797 1 140 2.9E-69 T 13-09-2016 THL1_RS07565 c756e4b5e59fa68bb3dec05bfe030b33 141 Gene3D G3DSA:3.30.300.20 48 140 1.7E-35 T 13-09-2016 IPR015946 K homology domain-like, alpha/beta THL1_RS07565 c756e4b5e59fa68bb3dec05bfe030b33 141 Pfam PF02566 OsmC-like protein 43 138 2.0E-17 T 13-09-2016 IPR003718 OsmC/Ohr family THL1_RS07565 c756e4b5e59fa68bb3dec05bfe030b33 141 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 7 139 9.5E-54 T 13-09-2016 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 THL1_RS20950 854ea41556077a59399b5f5f837cf4ae 166 SUPERFAMILY SSF54427 8 165 2.23E-41 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS20950 854ea41556077a59399b5f5f837cf4ae 166 Gene3D G3DSA:3.10.450.50 6 165 2.7E-45 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS20950 854ea41556077a59399b5f5f837cf4ae 166 PANTHER PTHR41534 6 166 3.4E-20 T 13-09-2016 THL1_RS20950 854ea41556077a59399b5f5f837cf4ae 166 Pfam PF00866 Ring hydroxylating beta subunit 23 155 3.1E-24 T 13-09-2016 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 THL1_RS04280 d121e884520f314e64fcc755c226a880 345 Gene3D G3DSA:1.10.8.60 145 223 1.1E-32 T 13-09-2016 THL1_RS04280 d121e884520f314e64fcc755c226a880 345 Gene3D G3DSA:3.40.50.300 1 139 1.4E-52 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04280 d121e884520f314e64fcc755c226a880 345 PANTHER PTHR34388 1 345 2.6E-79 T 13-09-2016 THL1_RS04280 d121e884520f314e64fcc755c226a880 345 Gene3D G3DSA:1.20.272.20 224 340 1.5E-42 T 13-09-2016 THL1_RS04280 d121e884520f314e64fcc755c226a880 345 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 16 336 9.0E-111 T 13-09-2016 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 THL1_RS04280 d121e884520f314e64fcc755c226a880 345 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 216 340 2.9E-14 T 13-09-2016 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS04280 d121e884520f314e64fcc755c226a880 345 SUPERFAMILY SSF48019 213 337 1.53E-33 T 13-09-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 THL1_RS04280 d121e884520f314e64fcc755c226a880 345 Pfam PF06144 DNA polymerase III, delta subunit 20 191 6.1E-31 T 13-09-2016 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 THL1_RS04280 d121e884520f314e64fcc755c226a880 345 SUPERFAMILY SSF52540 1 211 1.99E-47 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22120 b381a82681e084b860f66bede5e022c5 350 SUPERFAMILY SSF52540 23 254 1.02E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22120 b381a82681e084b860f66bede5e022c5 350 Gene3D G3DSA:1.10.10.10 260 331 8.5E-35 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS22120 b381a82681e084b860f66bede5e022c5 350 PANTHER PTHR13779 1 336 2.5E-189 T 13-09-2016 THL1_RS22120 b381a82681e084b860f66bede5e022c5 350 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 256 329 2.5E-33 T 13-09-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 THL1_RS22120 b381a82681e084b860f66bede5e022c5 350 Gene3D G3DSA:3.40.50.300 23 178 2.6E-29 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22120 b381a82681e084b860f66bede5e022c5 350 SMART SM00382 54 181 3.3E-12 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS22120 b381a82681e084b860f66bede5e022c5 350 SUPERFAMILY SSF46785 260 333 5.05E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS22120 b381a82681e084b860f66bede5e022c5 350 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 7 238 1.3E-116 T 13-09-2016 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 THL1_RS22120 b381a82681e084b860f66bede5e022c5 350 PANTHER PTHR13779:SF25 1 336 2.5E-189 T 13-09-2016 THL1_RS22120 b381a82681e084b860f66bede5e022c5 350 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 27 329 6.2E-150 T 13-09-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 THL1_RS22120 b381a82681e084b860f66bede5e022c5 350 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 253 336 6.0E-41 T 13-09-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 THL1_RS22120 b381a82681e084b860f66bede5e022c5 350 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 350 184.064 T 13-09-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 THL1_RS22120 b381a82681e084b860f66bede5e022c5 350 Gene3D G3DSA:1.10.8.60 186 258 3.3E-34 T 13-09-2016 THL1_RS08080 99c80690413fe53354ffbbd5c8611446 202 Pfam PF04205 FMN-binding domain 97 187 9.4E-17 T 13-09-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 THL1_RS08080 99c80690413fe53354ffbbd5c8611446 202 Hamap MF_00479 Electron transport complex subunit RsxG [rsxG]. 1 191 20.165 T 13-09-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 THL1_RS08080 99c80690413fe53354ffbbd5c8611446 202 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 7 190 1.8E-46 T 13-09-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 THL1_RS08080 99c80690413fe53354ffbbd5c8611446 202 PIRSF PIRSF006091 2 201 6.8E-54 T 13-09-2016 IPR010209 Electron transport complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 THL1_RS08080 99c80690413fe53354ffbbd5c8611446 202 SMART SM00900 97 189 6.6E-28 T 13-09-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 THL1_RS08080 99c80690413fe53354ffbbd5c8611446 202 PANTHER PTHR36118 4 196 3.3E-41 T 13-09-2016 THL1_RS08080 99c80690413fe53354ffbbd5c8611446 202 PANTHER PTHR36118:SF1 4 196 3.3E-41 T 13-09-2016 THL1_RS09890 7fe26012e93ddb93e3ea746a5bb4bb04 254 Pfam PF13005 zinc-finger binding domain of transposase IS66 54 95 1.1E-13 T 13-09-2016 IPR024474 Zinc-finger binding domain of transposase IS66 THL1_RS09890 7fe26012e93ddb93e3ea746a5bb4bb04 254 PANTHER PTHR33678:SF1 24 254 5.3E-43 T 13-09-2016 THL1_RS09890 7fe26012e93ddb93e3ea746a5bb4bb04 254 PANTHER PTHR33678 24 254 5.3E-43 T 13-09-2016 THL1_RS09890 7fe26012e93ddb93e3ea746a5bb4bb04 254 Pfam PF03050 Transposase IS66 family 110 251 8.4E-47 T 13-09-2016 IPR004291 Transposase, IS66 THL1_RS09890 7fe26012e93ddb93e3ea746a5bb4bb04 254 Pfam PF13007 Transposase C of IS166 homeodomain 9 44 1.2E-5 T 13-09-2016 IPR024463 Transposase TnpC, homeodomain THL1_RS08400 024fc58122e49cc1987bc66bb3e88174 273 PANTHER PTHR11732:SF98 1 265 3.6E-106 T 13-09-2016 THL1_RS08400 024fc58122e49cc1987bc66bb3e88174 273 PANTHER PTHR11732 1 265 3.6E-106 T 13-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta THL1_RS08400 024fc58122e49cc1987bc66bb3e88174 273 PRINTS PR00069 Aldo-keto reductase signature 195 219 4.9E-17 T 13-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 THL1_RS08400 024fc58122e49cc1987bc66bb3e88174 273 PRINTS PR00069 Aldo-keto reductase signature 125 142 4.9E-17 T 13-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 THL1_RS08400 024fc58122e49cc1987bc66bb3e88174 273 PRINTS PR00069 Aldo-keto reductase signature 95 113 4.9E-17 T 13-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 THL1_RS08400 024fc58122e49cc1987bc66bb3e88174 273 PRINTS PR00069 Aldo-keto reductase signature 39 63 4.9E-17 T 13-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 THL1_RS08400 024fc58122e49cc1987bc66bb3e88174 273 SUPERFAMILY SSF51430 4 266 9.56E-76 T 13-09-2016 IPR023210 NADP-dependent oxidoreductase domain THL1_RS08400 024fc58122e49cc1987bc66bb3e88174 273 Gene3D G3DSA:3.20.20.100 8 263 3.4E-72 T 13-09-2016 IPR023210 NADP-dependent oxidoreductase domain THL1_RS08400 024fc58122e49cc1987bc66bb3e88174 273 Pfam PF00248 Aldo/keto reductase family 15 258 1.8E-52 T 13-09-2016 IPR023210 NADP-dependent oxidoreductase domain THL1_RS11620 196e14ad25a4aa4d33d3c5ca8ee524bb 220 Gene3D G3DSA:1.20.1050.10 92 216 2.3E-22 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS11620 196e14ad25a4aa4d33d3c5ca8ee524bb 220 Gene3D G3DSA:3.40.30.10 2 91 1.2E-28 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS11620 196e14ad25a4aa4d33d3c5ca8ee524bb 220 Pfam PF13417 Glutathione S-transferase, N-terminal domain 5 77 6.5E-25 T 13-09-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THL1_RS11620 196e14ad25a4aa4d33d3c5ca8ee524bb 220 SUPERFAMILY SSF47616 80 211 7.66E-27 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS11620 196e14ad25a4aa4d33d3c5ca8ee524bb 220 PANTHER PTHR11260:SF285 1 214 5.7E-61 T 13-09-2016 THL1_RS11620 196e14ad25a4aa4d33d3c5ca8ee524bb 220 SUPERFAMILY SSF52833 1 103 5.5E-26 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS11620 196e14ad25a4aa4d33d3c5ca8ee524bb 220 Pfam PF14497 Glutathione S-transferase, C-terminal domain 132 204 8.9E-13 T 13-09-2016 IPR004046 Glutathione S-transferase, C-terminal THL1_RS11620 196e14ad25a4aa4d33d3c5ca8ee524bb 220 PANTHER PTHR11260 1 214 5.7E-61 T 13-09-2016 THL1_RS12335 e8a5c91122f81630d102783d4890e974 388 Pfam PF08007 Cupin superfamily protein 16 318 8.0E-104 T 13-09-2016 IPR003347 JmjC domain THL1_RS12335 e8a5c91122f81630d102783d4890e974 388 Gene3D G3DSA:2.60.120.650 7 215 4.0E-42 T 13-09-2016 THL1_RS12335 e8a5c91122f81630d102783d4890e974 388 SMART SM00558 101 229 2.3E-4 T 13-09-2016 IPR003347 JmjC domain THL1_RS12335 e8a5c91122f81630d102783d4890e974 388 PANTHER PTHR13096 9 372 2.3E-70 T 13-09-2016 THL1_RS12335 e8a5c91122f81630d102783d4890e974 388 SUPERFAMILY SSF51197 6 296 7.0E-78 T 13-09-2016 THL1_RS02325 bf6b40772824715e375cbf49a9cd6ac6 499 PANTHER PTHR11271:SF7 19 458 2.8E-64 T 13-09-2016 THL1_RS02325 bf6b40772824715e375cbf49a9cd6ac6 499 SUPERFAMILY SSF51556 102 381 2.37E-57 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS02325 bf6b40772824715e375cbf49a9cd6ac6 499 Gene3D G3DSA:3.20.20.140 106 391 2.5E-65 T 13-09-2016 THL1_RS02325 bf6b40772824715e375cbf49a9cd6ac6 499 PANTHER PTHR11271 19 458 2.8E-64 T 13-09-2016 THL1_RS02325 bf6b40772824715e375cbf49a9cd6ac6 499 Gene3D G3DSA:2.30.40.10 392 432 4.1E-7 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS02325 bf6b40772824715e375cbf49a9cd6ac6 499 Gene3D G3DSA:2.30.40.10 16 62 4.1E-7 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS02325 bf6b40772824715e375cbf49a9cd6ac6 499 SUPERFAMILY SSF51338 339 458 2.16E-28 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS02325 bf6b40772824715e375cbf49a9cd6ac6 499 SUPERFAMILY SSF51338 17 68 5.89E-5 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS02325 bf6b40772824715e375cbf49a9cd6ac6 499 Pfam PF01979 Amidohydrolase family 111 428 4.9E-27 T 13-09-2016 IPR006680 Amidohydrolase-related GO:0016787 THL1_RS15560 8e45ac6fd2b9bef78206743051ab88b4 270 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 262 5.2E-28 T 13-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase THL1_RS15560 8e45ac6fd2b9bef78206743051ab88b4 270 SUPERFAMILY SSF56219 1 269 8.38E-83 T 13-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase THL1_RS15560 8e45ac6fd2b9bef78206743051ab88b4 270 ProSitePatterns PS00727 AP endonucleases family 1 signature 2. 198 214 - T 13-09-2016 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 THL1_RS15560 8e45ac6fd2b9bef78206743051ab88b4 270 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 269 4.0E-85 T 13-09-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 THL1_RS15560 8e45ac6fd2b9bef78206743051ab88b4 270 PANTHER PTHR22748:SF7 1 269 4.5E-131 T 13-09-2016 THL1_RS15560 8e45ac6fd2b9bef78206743051ab88b4 270 Gene3D G3DSA:3.60.10.10 1 269 6.9E-82 T 13-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase THL1_RS15560 8e45ac6fd2b9bef78206743051ab88b4 270 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 13-09-2016 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 THL1_RS15560 8e45ac6fd2b9bef78206743051ab88b4 270 PANTHER PTHR22748 1 269 4.5E-131 T 13-09-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 THL1_RS15560 8e45ac6fd2b9bef78206743051ab88b4 270 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 269 1.5E-97 T 13-09-2016 THL1_RS06100 245fe6f58e9a3b6fdcc675fc344da79b 80 Gene3D G3DSA:1.10.1220.10 32 73 1.5E-8 T 13-09-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THL1_RS06100 245fe6f58e9a3b6fdcc675fc344da79b 80 SUPERFAMILY SSF47598 35 77 8.89E-9 T 13-09-2016 IPR010985 Ribbon-helix-helix GO:0006355 THL1_RS09040 92a0c15bd4faa7aeaae92d3a0a945721 330 SUPERFAMILY SSF53383 3 319 3.98E-49 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS09040 92a0c15bd4faa7aeaae92d3a0a945721 330 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 189 202 - T 13-09-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 THL1_RS09040 92a0c15bd4faa7aeaae92d3a0a945721 330 PANTHER PTHR11751 6 328 3.7E-49 T 13-09-2016 THL1_RS09040 92a0c15bd4faa7aeaae92d3a0a945721 330 Pfam PF00155 Aminotransferase class I and II 52 270 2.0E-25 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS09040 92a0c15bd4faa7aeaae92d3a0a945721 330 Gene3D G3DSA:3.40.640.10 42 237 3.4E-44 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS09040 92a0c15bd4faa7aeaae92d3a0a945721 330 PANTHER PTHR11751:SF3 6 328 3.7E-49 T 13-09-2016 THL1_RS09040 92a0c15bd4faa7aeaae92d3a0a945721 330 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 4 322 2.3E-111 T 13-09-2016 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443|UniPathway: UPA00148 THL1_RS12615 5004da1777e6dc05800f3f0dc87e82d5 262 Pfam PF00561 alpha/beta hydrolase fold 22 134 6.8E-16 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS12615 5004da1777e6dc05800f3f0dc87e82d5 262 Gene3D G3DSA:3.40.50.1820 3 261 6.2E-62 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS12615 5004da1777e6dc05800f3f0dc87e82d5 262 TIGRFAM TIGR02427 protocat_pcaD: 3-oxoadipate enol-lactonase 11 261 2.0E-100 T 13-09-2016 IPR026968 3-oxoadipate enol-lactonase 1/2 GO:0042952|GO:0047570 KEGG: 00362+3.1.1.24|MetaCyc: PWY-6185|UniPathway: UPA00157 THL1_RS12615 5004da1777e6dc05800f3f0dc87e82d5 262 PANTHER PTHR10992 1 262 1.1E-134 T 13-09-2016 THL1_RS12615 5004da1777e6dc05800f3f0dc87e82d5 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 6.0E-9 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS12615 5004da1777e6dc05800f3f0dc87e82d5 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 6.0E-9 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS12615 5004da1777e6dc05800f3f0dc87e82d5 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 6.0E-9 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS12615 5004da1777e6dc05800f3f0dc87e82d5 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 207 221 6.0E-9 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS12615 5004da1777e6dc05800f3f0dc87e82d5 262 SUPERFAMILY SSF53474 2 260 5.31E-66 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS12615 5004da1777e6dc05800f3f0dc87e82d5 262 PANTHER PTHR10992:SF861 1 262 1.1E-134 T 13-09-2016 THL1_RS23885 400921069c4d42066810131726f92e1b 455 PANTHER PTHR11662 15 450 4.1E-168 T 13-09-2016 THL1_RS23885 400921069c4d42066810131726f92e1b 455 PANTHER PTHR11662:SF270 15 450 4.1E-168 T 13-09-2016 THL1_RS23885 400921069c4d42066810131726f92e1b 455 Gene3D G3DSA:1.20.1250.20 232 432 4.0E-16 T 13-09-2016 THL1_RS23885 400921069c4d42066810131726f92e1b 455 Pfam PF07690 Major Facilitator Superfamily 21 382 8.5E-46 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS23885 400921069c4d42066810131726f92e1b 455 SUPERFAMILY SSF103473 10 436 6.93E-64 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS23885 400921069c4d42066810131726f92e1b 455 Gene3D G3DSA:1.20.1250.20 15 212 4.0E-34 T 13-09-2016 THL1_RS02165 2141641335b4d17bb9427ac1df795e0d 352 TIGRFAM TIGR00433 bioB: biotin synthase 20 316 6.2E-125 T 13-09-2016 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 THL1_RS02165 2141641335b4d17bb9427ac1df795e0d 352 PIRSF PIRSF001619 1 325 1.0E-136 T 13-09-2016 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 THL1_RS02165 2141641335b4d17bb9427ac1df795e0d 352 PANTHER PTHR22976:SF1 1 352 3.7E-193 T 13-09-2016 THL1_RS02165 2141641335b4d17bb9427ac1df795e0d 352 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 226 316 1.6E-20 T 13-09-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 THL1_RS02165 2141641335b4d17bb9427ac1df795e0d 352 PANTHER PTHR22976 1 352 3.7E-193 T 13-09-2016 THL1_RS02165 2141641335b4d17bb9427ac1df795e0d 352 Pfam PF04055 Radical SAM superfamily 56 207 2.9E-14 T 13-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 THL1_RS02165 2141641335b4d17bb9427ac1df795e0d 352 SMART SM00729 49 261 2.5E-39 T 13-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THL1_RS02165 2141641335b4d17bb9427ac1df795e0d 352 Hamap MF_01694 Biotin synthase [bioB]. 11 319 41.935 T 13-09-2016 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 THL1_RS02165 2141641335b4d17bb9427ac1df795e0d 352 SUPERFAMILY SSF102114 11 320 1.09E-92 T 13-09-2016 THL1_RS02165 2141641335b4d17bb9427ac1df795e0d 352 Gene3D G3DSA:3.20.20.70 11 320 3.8E-105 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS02165 2141641335b4d17bb9427ac1df795e0d 352 SMART SM00876 226 318 6.4E-48 T 13-09-2016 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380|UniPathway: UPA00078 THL1_RS09110 318726f54545b2807b9f60d1139cc1ec 157 SUPERFAMILY SSF54909 61 149 4.69E-20 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS09110 318726f54545b2807b9f60d1139cc1ec 157 Pfam PF01037 Lrp/AsnC ligand binding domain 67 139 4.7E-18 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS09110 318726f54545b2807b9f60d1139cc1ec 157 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 1.5E-19 T 13-09-2016 THL1_RS09110 318726f54545b2807b9f60d1139cc1ec 157 Gene3D G3DSA:3.30.70.920 55 137 2.3E-27 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS09110 318726f54545b2807b9f60d1139cc1ec 157 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 13-09-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site THL1_RS09110 318726f54545b2807b9f60d1139cc1ec 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.0E-12 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS09110 318726f54545b2807b9f60d1139cc1ec 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.0E-12 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS09110 318726f54545b2807b9f60d1139cc1ec 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.0E-12 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS09110 318726f54545b2807b9f60d1139cc1ec 157 SMART SM00344 1 110 3.6E-43 T 13-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 THL1_RS09110 318726f54545b2807b9f60d1139cc1ec 157 PANTHER PTHR30154:SF17 1 149 1.5E-67 T 13-09-2016 THL1_RS09110 318726f54545b2807b9f60d1139cc1ec 157 PANTHER PTHR30154 1 149 1.5E-67 T 13-09-2016 THL1_RS09110 318726f54545b2807b9f60d1139cc1ec 157 Gene3D G3DSA:1.10.10.10 2 53 1.8E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09110 318726f54545b2807b9f60d1139cc1ec 157 SUPERFAMILY SSF46785 1 84 9.86E-16 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS23765 935eac422fba825654ee7b1fd4984e1f 209 PANTHER PTHR30086 1 207 2.2E-59 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS23765 935eac422fba825654ee7b1fd4984e1f 209 PANTHER PTHR30086:SF2 1 207 2.2E-59 T 13-09-2016 THL1_RS23765 935eac422fba825654ee7b1fd4984e1f 209 PIRSF PIRSF006324 1 208 1.0E-53 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS23765 935eac422fba825654ee7b1fd4984e1f 209 Pfam PF01810 LysE type translocator 16 205 6.8E-35 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS00715 41802e63011f4db169c13f440f86d43f 635 Pfam PF00990 Diguanylate cyclase, GGDEF domain 209 365 4.6E-46 T 13-09-2016 IPR000160 GGDEF domain THL1_RS00715 41802e63011f4db169c13f440f86d43f 635 Pfam PF00563 EAL domain 386 621 5.1E-79 T 13-09-2016 IPR001633 EAL domain THL1_RS00715 41802e63011f4db169c13f440f86d43f 635 Pfam PF13426 PAS domain 95 196 3.6E-15 T 13-09-2016 IPR000014 PAS domain THL1_RS00715 41802e63011f4db169c13f440f86d43f 635 Gene3D G3DSA:3.30.450.20 93 196 1.9E-29 T 13-09-2016 THL1_RS00715 41802e63011f4db169c13f440f86d43f 635 PANTHER PTHR10799 97 480 7.0E-85 T 13-09-2016 THL1_RS00715 41802e63011f4db169c13f440f86d43f 635 PANTHER PTHR10799:SF710 97 480 7.0E-85 T 13-09-2016 THL1_RS00715 41802e63011f4db169c13f440f86d43f 635 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 84 205 1.7E-19 T 13-09-2016 IPR000014 PAS domain THL1_RS00715 41802e63011f4db169c13f440f86d43f 635 SUPERFAMILY SSF55785 89 196 5.06E-30 T 13-09-2016 IPR000014 PAS domain THL1_RS00715 41802e63011f4db169c13f440f86d43f 635 SMART SM00267 198 370 2.0E-60 T 13-09-2016 IPR000160 GGDEF domain THL1_RS00715 41802e63011f4db169c13f440f86d43f 635 SMART SM00052 380 626 3.2E-124 T 13-09-2016 IPR001633 EAL domain THL1_RS00715 41802e63011f4db169c13f440f86d43f 635 Gene3D G3DSA:3.30.70.270 210 378 1.3E-54 T 13-09-2016 THL1_RS00715 41802e63011f4db169c13f440f86d43f 635 Gene3D G3DSA:3.20.20.450 383 633 1.3E-102 T 13-09-2016 IPR001633 EAL domain THL1_RS00715 41802e63011f4db169c13f440f86d43f 635 SUPERFAMILY SSF141868 386 633 6.67E-93 T 13-09-2016 IPR001633 EAL domain THL1_RS00715 41802e63011f4db169c13f440f86d43f 635 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 205 367 4.3E-35 T 13-09-2016 IPR000160 GGDEF domain THL1_RS00715 41802e63011f4db169c13f440f86d43f 635 SMART SM00091 84 150 2.7E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS00715 41802e63011f4db169c13f440f86d43f 635 SUPERFAMILY SSF55073 214 372 7.45E-47 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS00715 41802e63011f4db169c13f440f86d43f 635 SMART SM00086 156 198 2.6E-5 T 13-09-2016 IPR001610 PAC motif THL1_RS05420 f01b046359e8bed4c494b1ae7a6d5e63 79 Pfam PF01722 BolA-like protein 22 71 5.1E-8 T 13-09-2016 IPR002634 BolA protein THL1_RS05420 f01b046359e8bed4c494b1ae7a6d5e63 79 SUPERFAMILY SSF82657 2 78 4.19E-21 T 13-09-2016 IPR002634 BolA protein THL1_RS05420 f01b046359e8bed4c494b1ae7a6d5e63 79 Gene3D G3DSA:3.30.300.90 2 78 4.2E-20 T 13-09-2016 IPR002634 BolA protein THL1_RS05420 f01b046359e8bed4c494b1ae7a6d5e63 79 PIRSF PIRSF003113 1 79 2.5E-15 T 13-09-2016 IPR002634 BolA protein THL1_RS05980 a9ac6f79212609bb5bb201208191a43e 346 SUPERFAMILY SSF47413 15 82 1.03E-5 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS05980 a9ac6f79212609bb5bb201208191a43e 346 PANTHER PTHR34475 3 346 8.0E-49 T 13-09-2016 THL1_RS05980 a9ac6f79212609bb5bb201208191a43e 346 Pfam PF13413 Helix-turn-helix domain 20 78 2.0E-21 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS05980 a9ac6f79212609bb5bb201208191a43e 346 Pfam PF13464 Domain of unknown function (DUF4115) 271 344 4.9E-26 T 13-09-2016 IPR025194 Domain of unknown function DUF4115 THL1_RS05980 a9ac6f79212609bb5bb201208191a43e 346 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 30 56 - T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS05980 a9ac6f79212609bb5bb201208191a43e 346 Gene3D G3DSA:1.10.260.40 15 85 5.1E-7 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS05980 a9ac6f79212609bb5bb201208191a43e 346 PANTHER PTHR34475:SF1 3 346 8.0E-49 T 13-09-2016 THL1_RS05880 73bf3122c3413cf394a69f565beac591 349 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 337 47.591 T 13-09-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS05880 73bf3122c3413cf394a69f565beac591 349 SUPERFAMILY SSF111337 1 336 2.75E-137 T 13-09-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS05880 73bf3122c3413cf394a69f565beac591 349 PANTHER PTHR30307 2 343 1.4E-178 T 13-09-2016 THL1_RS05880 73bf3122c3413cf394a69f565beac591 349 Gene3D G3DSA:2.40.10.240 64 132 6.6E-16 T 13-09-2016 THL1_RS05880 73bf3122c3413cf394a69f565beac591 349 Pfam PF02547 Queuosine biosynthesis protein 4 336 3.7E-136 T 13-09-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS05880 73bf3122c3413cf394a69f565beac591 349 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 337 1.2E-148 T 13-09-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS05880 73bf3122c3413cf394a69f565beac591 349 PANTHER PTHR30307:SF0 2 343 1.4E-178 T 13-09-2016 THL1_RS05880 73bf3122c3413cf394a69f565beac591 349 Gene3D G3DSA:3.40.1780.10 175 337 9.4E-103 T 13-09-2016 THL1_RS05880 73bf3122c3413cf394a69f565beac591 349 Gene3D G3DSA:3.40.1780.10 1 62 9.4E-103 T 13-09-2016 THL1_RS26335 4359b5603a3a985fe0356ad733ab5bed 422 SUPERFAMILY SSF51735 162 413 2.33E-83 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS26335 4359b5603a3a985fe0356ad733ab5bed 422 ProSitePatterns PS00331 Malic enzymes signature. 158 174 - T 13-09-2016 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 THL1_RS26335 4359b5603a3a985fe0356ad733ab5bed 422 SMART SM00919 162 398 9.2E-143 T 13-09-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 THL1_RS26335 4359b5603a3a985fe0356ad733ab5bed 422 PANTHER PTHR23406 370 411 4.1E-170 T 13-09-2016 THL1_RS26335 4359b5603a3a985fe0356ad733ab5bed 422 PANTHER PTHR23406 32 353 4.1E-170 T 13-09-2016 THL1_RS26335 4359b5603a3a985fe0356ad733ab5bed 422 SMART SM01274 17 150 1.0E-77 T 13-09-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 THL1_RS26335 4359b5603a3a985fe0356ad733ab5bed 422 Gene3D G3DSA:3.40.50.10380 7 159 6.1E-49 T 13-09-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 THL1_RS26335 4359b5603a3a985fe0356ad733ab5bed 422 PIRSF PIRSF000106 43 418 2.8E-71 T 13-09-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 THL1_RS26335 4359b5603a3a985fe0356ad733ab5bed 422 Pfam PF03949 Malic enzyme, NAD binding domain 164 355 6.2E-26 T 13-09-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 THL1_RS26335 4359b5603a3a985fe0356ad733ab5bed 422 Gene3D G3DSA:3.40.50.720 160 417 1.5E-85 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS26335 4359b5603a3a985fe0356ad733ab5bed 422 SUPERFAMILY SSF53223 9 160 2.23E-51 T 13-09-2016 THL1_RS26335 4359b5603a3a985fe0356ad733ab5bed 422 Pfam PF00390 Malic enzyme, N-terminal domain 19 149 3.3E-25 T 13-09-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 THL1_RS05620 58ac2406e7fee2c9528d0170e62691d1 454 Pfam PF08245 Mur ligase middle domain 107 296 2.2E-46 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05620 58ac2406e7fee2c9528d0170e62691d1 454 Gene3D G3DSA:3.90.190.20 315 448 1.2E-42 T 13-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 THL1_RS05620 58ac2406e7fee2c9528d0170e62691d1 454 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 447 4.1E-144 T 13-09-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS05620 58ac2406e7fee2c9528d0170e62691d1 454 Gene3D G3DSA:3.40.1190.10 84 313 1.5E-68 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05620 58ac2406e7fee2c9528d0170e62691d1 454 SUPERFAMILY SSF63418 4 98 4.19E-24 T 13-09-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05620 58ac2406e7fee2c9528d0170e62691d1 454 PANTHER PTHR23135 13 447 3.2E-159 T 13-09-2016 THL1_RS05620 58ac2406e7fee2c9528d0170e62691d1 454 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 5 448 32.957 T 13-09-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS05620 58ac2406e7fee2c9528d0170e62691d1 454 Pfam PF02875 Mur ligase family, glutamate ligase domain 317 384 2.0E-11 T 13-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 THL1_RS05620 58ac2406e7fee2c9528d0170e62691d1 454 PANTHER PTHR23135:SF3 13 447 3.2E-159 T 13-09-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS05620 58ac2406e7fee2c9528d0170e62691d1 454 SUPERFAMILY SSF53623 103 315 8.63E-54 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05620 58ac2406e7fee2c9528d0170e62691d1 454 Gene3D G3DSA:3.40.1390.10 4 82 3.3E-24 T 13-09-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05620 58ac2406e7fee2c9528d0170e62691d1 454 Pfam PF01225 Mur ligase family, catalytic domain 25 94 2.2E-8 T 13-09-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05620 58ac2406e7fee2c9528d0170e62691d1 454 SUPERFAMILY SSF53244 316 447 4.35E-35 T 13-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 SUPERFAMILY SSF88659 172 246 2.31E-14 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 PANTHER PTHR30603 49 334 1.6E-182 T 13-09-2016 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 Pfam PF00140 Sigma-70 factor, region 1.2 61 93 5.7E-13 T 13-09-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 96 322 9.4E-38 T 13-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 Pfam PF04539 Sigma-70 region 3 179 253 1.1E-20 T 13-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 PANTHER PTHR30603:SF15 49 334 1.6E-182 T 13-09-2016 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 Pfam PF04545 Sigma-70, region 4 267 320 1.6E-17 T 13-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 SUPERFAMILY SSF88946 61 169 2.75E-45 T 13-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 SUPERFAMILY SSF88659 230 327 5.79E-26 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 Gene3D G3DSA:1.10.10.10 262 328 1.8E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 Hamap MF_00959 RNA polymerase sigma factor RpoS [rpoS]. 7 333 40.84 T 13-09-2016 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 Gene3D G3DSA:1.10.10.10 172 221 8.8E-15 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 Gene3D G3DSA:1.10.601.10 39 168 7.8E-59 T 13-09-2016 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 TIGRFAM TIGR02394 rpoS_proteo: RNA polymerase sigma factor RpoS 56 333 2.1E-141 T 13-09-2016 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 292 318 - T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 Pfam PF04542 Sigma-70 region 2 99 168 6.7E-22 T 13-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 PRINTS PR00046 Major sigma-70 factor signature 271 283 4.9E-28 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 PRINTS PR00046 Major sigma-70 factor signature 123 136 4.9E-28 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 PRINTS PR00046 Major sigma-70 factor signature 307 318 4.9E-28 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 PRINTS PR00046 Major sigma-70 factor signature 292 307 4.9E-28 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 PRINTS PR00046 Major sigma-70 factor signature 147 155 4.9E-28 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS22485 81ed29656d0afd25290da68c978dadfc 334 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 123 136 - T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS12340 337eb830ed8d3d4af5dc905e0e4e1732 456 PANTHER PTHR11444:SF17 4 456 0.0 T 13-09-2016 THL1_RS12340 337eb830ed8d3d4af5dc905e0e4e1732 456 ProSitePatterns PS00163 Fumarate lyases signature. 295 304 - T 13-09-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 THL1_RS12340 337eb830ed8d3d4af5dc905e0e4e1732 456 PRINTS PR00149 Fumarate lyase superfamily signature 252 279 1.7E-18 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS12340 337eb830ed8d3d4af5dc905e0e4e1732 456 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 1.7E-18 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS12340 337eb830ed8d3d4af5dc905e0e4e1732 456 PRINTS PR00149 Fumarate lyase superfamily signature 295 311 1.7E-18 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS12340 337eb830ed8d3d4af5dc905e0e4e1732 456 PRINTS PR00149 Fumarate lyase superfamily signature 163 181 1.7E-18 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS12340 337eb830ed8d3d4af5dc905e0e4e1732 456 Pfam PF00206 Lyase 14 313 2.5E-66 T 13-09-2016 IPR022761 Fumarate lyase, N-terminal THL1_RS12340 337eb830ed8d3d4af5dc905e0e4e1732 456 Gene3D G3DSA:1.10.275.10 1 119 3.8E-48 T 13-09-2016 IPR024083 Fumarase/histidase, N-terminal THL1_RS12340 337eb830ed8d3d4af5dc905e0e4e1732 456 PANTHER PTHR11444 4 456 0.0 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS12340 337eb830ed8d3d4af5dc905e0e4e1732 456 SUPERFAMILY SSF48557 4 448 1.43E-106 T 13-09-2016 IPR008948 L-Aspartase-like GO:0003824 THL1_RS12340 337eb830ed8d3d4af5dc905e0e4e1732 456 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 455 1.1E-135 T 13-09-2016 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 THL1_RS12340 337eb830ed8d3d4af5dc905e0e4e1732 456 Gene3D G3DSA:1.20.200.10 120 390 5.9E-90 T 13-09-2016 THL1_RS12340 337eb830ed8d3d4af5dc905e0e4e1732 456 Gene3D G3DSA:1.10.40.30 391 446 1.0E-32 T 13-09-2016 THL1_RS12340 337eb830ed8d3d4af5dc905e0e4e1732 456 Pfam PF08328 Adenylosuccinate lyase C-terminal 332 446 2.3E-51 T 13-09-2016 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 THL1_RS14180 98be4e7d7c6687c5aafe256a56c264f2 264 PANTHER PTHR30294:SF13 12 251 4.9E-72 T 13-09-2016 THL1_RS14180 98be4e7d7c6687c5aafe256a56c264f2 264 PRINTS PR00164 ABC-2 type transport system membrane protein signature 27 48 1.2E-7 T 13-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THL1_RS14180 98be4e7d7c6687c5aafe256a56c264f2 264 PRINTS PR00164 ABC-2 type transport system membrane protein signature 144 168 1.2E-7 T 13-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THL1_RS14180 98be4e7d7c6687c5aafe256a56c264f2 264 PRINTS PR00164 ABC-2 type transport system membrane protein signature 181 200 1.2E-7 T 13-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THL1_RS14180 98be4e7d7c6687c5aafe256a56c264f2 264 PANTHER PTHR30294 12 251 4.9E-72 T 13-09-2016 THL1_RS14180 98be4e7d7c6687c5aafe256a56c264f2 264 Pfam PF01061 ABC-2 type transporter 10 227 1.8E-36 T 13-09-2016 IPR013525 ABC-2 type transporter GO:0016020 THL1_RS14180 98be4e7d7c6687c5aafe256a56c264f2 264 PIRSF PIRSF006648 9 257 9.3E-38 T 13-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THL1_RS14180 98be4e7d7c6687c5aafe256a56c264f2 264 TIGRFAM TIGR03861 phenyl_ABC_PedC: alcohol ABC transporter, permease protein 6 258 2.5E-139 T 13-09-2016 IPR022403 Alcohol ABC transporter, permease protein THL1_RS22095 76c43237ee8f78637e1ede06e573712a 434 PANTHER PTHR11731:SF123 157 431 8.4E-105 T 13-09-2016 THL1_RS22095 76c43237ee8f78637e1ede06e573712a 434 PANTHER PTHR11731:SF123 1 120 8.4E-105 T 13-09-2016 THL1_RS22095 76c43237ee8f78637e1ede06e573712a 434 SUPERFAMILY SSF52964 28 158 1.24E-40 T 13-09-2016 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 THL1_RS22095 76c43237ee8f78637e1ede06e573712a 434 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 17 430 3.1E-153 T 13-09-2016 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 THL1_RS22095 76c43237ee8f78637e1ede06e573712a 434 Gene3D G3DSA:3.40.50.10070 26 149 4.3E-47 T 13-09-2016 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 THL1_RS22095 76c43237ee8f78637e1ede06e573712a 434 Hamap MF_00671 Protein TolB [tolB]. 4 429 34.549 T 13-09-2016 IPR014167 Tol-Pal system beta propeller repeat-containing protein, TolB GO:0017038|GO:0042597 THL1_RS22095 76c43237ee8f78637e1ede06e573712a 434 Pfam PF04052 TolB amino-terminal domain 25 126 4.8E-31 T 13-09-2016 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 THL1_RS22095 76c43237ee8f78637e1ede06e573712a 434 PANTHER PTHR11731 1 120 8.4E-105 T 13-09-2016 THL1_RS22095 76c43237ee8f78637e1ede06e573712a 434 PANTHER PTHR11731 157 431 8.4E-105 T 13-09-2016 THL1_RS22095 76c43237ee8f78637e1ede06e573712a 434 SUPERFAMILY SSF69304 153 431 1.83E-52 T 13-09-2016 THL1_RS22095 76c43237ee8f78637e1ede06e573712a 434 Pfam PF07676 WD40-like Beta Propeller Repeat 279 314 2.9E-12 T 13-09-2016 IPR011659 WD40-like Beta Propeller THL1_RS22095 76c43237ee8f78637e1ede06e573712a 434 Pfam PF07676 WD40-like Beta Propeller Repeat 371 401 0.001 T 13-09-2016 IPR011659 WD40-like Beta Propeller THL1_RS22095 76c43237ee8f78637e1ede06e573712a 434 Pfam PF07676 WD40-like Beta Propeller Repeat 201 227 7.5E-5 T 13-09-2016 IPR011659 WD40-like Beta Propeller THL1_RS22095 76c43237ee8f78637e1ede06e573712a 434 Pfam PF07676 WD40-like Beta Propeller Repeat 236 271 9.2E-11 T 13-09-2016 IPR011659 WD40-like Beta Propeller THL1_RS22095 76c43237ee8f78637e1ede06e573712a 434 Gene3D G3DSA:2.130.10.10 150 431 1.5E-68 T 13-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THL1_RS13135 8a0cb39ab6583c6e78d22dba50b452a0 186 Pfam PF02469 Fasciclin domain 51 185 6.3E-34 T 13-09-2016 IPR000782 FAS1 domain THL1_RS13135 8a0cb39ab6583c6e78d22dba50b452a0 186 PANTHER PTHR10900 26 185 1.1E-49 T 13-09-2016 THL1_RS13135 8a0cb39ab6583c6e78d22dba50b452a0 186 SUPERFAMILY SSF82153 40 185 6.02E-40 T 13-09-2016 IPR000782 FAS1 domain THL1_RS13135 8a0cb39ab6583c6e78d22dba50b452a0 186 SMART SM00554 75 186 2.9E-26 T 13-09-2016 IPR000782 FAS1 domain THL1_RS13135 8a0cb39ab6583c6e78d22dba50b452a0 186 Gene3D G3DSA:2.30.180.10 39 185 4.5E-39 T 13-09-2016 IPR000782 FAS1 domain THL1_RS17665 33248636d3ef6279fc22f456940d3834 307 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 107 121 5.1E-8 T 13-09-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 THL1_RS17665 33248636d3ef6279fc22f456940d3834 307 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 150 163 5.1E-8 T 13-09-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 THL1_RS17665 33248636d3ef6279fc22f456940d3834 307 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 3 19 5.1E-8 T 13-09-2016 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 THL1_RS17665 33248636d3ef6279fc22f456940d3834 307 Pfam PF00145 C-5 cytosine-specific DNA methylase 3 170 1.0E-29 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS17665 33248636d3ef6279fc22f456940d3834 307 Pfam PF00145 C-5 cytosine-specific DNA methylase 248 303 1.7E-4 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS17665 33248636d3ef6279fc22f456940d3834 307 PANTHER PTHR10629 2 161 4.9E-20 T 13-09-2016 THL1_RS17665 33248636d3ef6279fc22f456940d3834 307 SUPERFAMILY SSF53335 2 305 3.71E-60 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS17665 33248636d3ef6279fc22f456940d3834 307 Gene3D G3DSA:3.40.50.150 1 178 5.4E-40 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS17665 33248636d3ef6279fc22f456940d3834 307 PANTHER PTHR10629:SF32 2 161 4.9E-20 T 13-09-2016 THL1_RS17665 33248636d3ef6279fc22f456940d3834 307 Gene3D G3DSA:3.90.120.10 247 291 3.9E-4 T 13-09-2016 THL1_RS14310 d8351c84250aa373fc2c22873d6fc0b1 289 Pfam PF12833 Helix-turn-helix domain 209 286 3.2E-19 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS14310 d8351c84250aa373fc2c22873d6fc0b1 289 PANTHER PTHR11019:SF45 9 286 4.5E-72 T 13-09-2016 THL1_RS14310 d8351c84250aa373fc2c22873d6fc0b1 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 270 286 2.1E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS14310 d8351c84250aa373fc2c22873d6fc0b1 289 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 255 270 2.1E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS14310 d8351c84250aa373fc2c22873d6fc0b1 289 SUPERFAMILY SSF46689 242 286 1.16E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS14310 d8351c84250aa373fc2c22873d6fc0b1 289 Gene3D G3DSA:1.10.10.60 192 239 5.9E-6 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS14310 d8351c84250aa373fc2c22873d6fc0b1 289 PANTHER PTHR11019 9 286 4.5E-72 T 13-09-2016 THL1_RS14310 d8351c84250aa373fc2c22873d6fc0b1 289 SUPERFAMILY SSF51182 30 149 4.98E-11 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS14310 d8351c84250aa373fc2c22873d6fc0b1 289 Pfam PF02311 AraC-like ligand binding domain 36 163 2.2E-5 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS14310 d8351c84250aa373fc2c22873d6fc0b1 289 Gene3D G3DSA:1.10.10.60 241 287 7.2E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS14310 d8351c84250aa373fc2c22873d6fc0b1 289 Gene3D G3DSA:2.60.120.10 41 101 9.4E-8 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS14310 d8351c84250aa373fc2c22873d6fc0b1 289 SMART SM00342 203 286 4.0E-23 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS08190 fb08998493e740ce521e2c99cbbe031a 239 Pfam PF00691 OmpA family 120 198 1.9E-13 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS08190 fb08998493e740ce521e2c99cbbe031a 239 SUPERFAMILY SSF103088 93 206 2.35E-25 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS08190 fb08998493e740ce521e2c99cbbe031a 239 ProSitePatterns PS01068 OmpA-like domain. 136 180 - T 13-09-2016 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 THL1_RS08190 fb08998493e740ce521e2c99cbbe031a 239 Gene3D G3DSA:3.30.1330.60 83 204 5.0E-25 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS08190 fb08998493e740ce521e2c99cbbe031a 239 PANTHER PTHR30128 65 213 2.0E-31 T 13-09-2016 THL1_RS23285 9b7306490220009fed953d15031270d5 442 ProSitePatterns PS00216 Sugar transport proteins signature 1. 293 310 - T 13-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 THL1_RS23285 9b7306490220009fed953d15031270d5 442 Gene3D G3DSA:1.20.1250.20 233 427 1.5E-24 T 13-09-2016 THL1_RS23285 9b7306490220009fed953d15031270d5 442 Gene3D G3DSA:1.20.1250.20 11 213 7.8E-24 T 13-09-2016 THL1_RS23285 9b7306490220009fed953d15031270d5 442 PANTHER PTHR23508:SF11 5 442 3.0E-244 T 13-09-2016 THL1_RS23285 9b7306490220009fed953d15031270d5 442 PANTHER PTHR23508 5 442 3.0E-244 T 13-09-2016 THL1_RS23285 9b7306490220009fed953d15031270d5 442 SUPERFAMILY SSF103473 11 424 5.75E-67 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS23285 9b7306490220009fed953d15031270d5 442 Pfam PF00083 Sugar (and other) transporter 15 420 6.7E-29 T 13-09-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 THL1_RS23285 9b7306490220009fed953d15031270d5 442 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 13-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 THL1_RS07805 d2659b4151a9618689fbca4e7c57be24 303 PANTHER PTHR30126 13 303 4.4E-69 T 13-09-2016 THL1_RS07805 d2659b4151a9618689fbca4e7c57be24 303 Pfam PF03466 LysR substrate binding domain 98 301 2.3E-23 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS07805 d2659b4151a9618689fbca4e7c57be24 303 PANTHER PTHR30126:SF16 13 303 4.4E-69 T 13-09-2016 THL1_RS07805 d2659b4151a9618689fbca4e7c57be24 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 74 1.3E-16 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS07805 d2659b4151a9618689fbca4e7c57be24 303 SUPERFAMILY SSF53850 100 301 2.95E-22 T 13-09-2016 THL1_RS07805 d2659b4151a9618689fbca4e7c57be24 303 Gene3D G3DSA:3.40.190.10 93 209 5.5E-11 T 13-09-2016 THL1_RS07805 d2659b4151a9618689fbca4e7c57be24 303 SUPERFAMILY SSF46785 13 99 1.39E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07805 d2659b4151a9618689fbca4e7c57be24 303 Gene3D G3DSA:1.10.10.10 13 92 5.8E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS17540 33be865954db2c7e5dbb95c09f9638a3 501 PANTHER PTHR35004:SF2 15 441 1.0E-74 T 13-09-2016 THL1_RS17540 33be865954db2c7e5dbb95c09f9638a3 501 Gene3D G3DSA:1.10.10.60 17 47 1.1E-4 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17540 33be865954db2c7e5dbb95c09f9638a3 501 Gene3D G3DSA:3.30.420.10 156 276 2.1E-4 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS17540 33be865954db2c7e5dbb95c09f9638a3 501 Pfam PF00665 Integrase core domain 127 251 2.0E-15 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS17540 33be865954db2c7e5dbb95c09f9638a3 501 PANTHER PTHR35004 15 441 1.0E-74 T 13-09-2016 THL1_RS08600 935bd7618bb9f00bc54dba6eb107b5f0 441 PANTHER PTHR23505 10 422 1.0E-78 T 13-09-2016 THL1_RS08600 935bd7618bb9f00bc54dba6eb107b5f0 441 SUPERFAMILY SSF103473 8 417 3.4E-69 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS08600 935bd7618bb9f00bc54dba6eb107b5f0 441 Pfam PF07690 Major Facilitator Superfamily 17 368 5.3E-42 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS08600 935bd7618bb9f00bc54dba6eb107b5f0 441 Gene3D G3DSA:1.20.1250.20 11 191 2.3E-41 T 13-09-2016 THL1_RS08600 935bd7618bb9f00bc54dba6eb107b5f0 441 Gene3D G3DSA:1.20.1250.20 207 415 2.7E-17 T 13-09-2016 THL1_RS07875 6378d054166dd0ff99a707bfba3c051b 479 PANTHER PTHR11785 16 471 5.9E-229 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS07875 6378d054166dd0ff99a707bfba3c051b 479 ProSitePatterns PS00218 Amino acid permeases signature. 49 80 - T 13-09-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 THL1_RS07875 6378d054166dd0ff99a707bfba3c051b 479 PIRSF PIRSF006060 3 472 6.1E-76 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS07875 6378d054166dd0ff99a707bfba3c051b 479 PANTHER PTHR11785:SF399 16 471 5.9E-229 T 13-09-2016 THL1_RS07875 6378d054166dd0ff99a707bfba3c051b 479 Pfam PF00324 Amino acid permease 24 460 4.0E-118 T 13-09-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 THL1_RS26875 10370e6b66b218df67d3a6eebc8ba2b2 307 SUPERFAMILY SSF56349 54 256 1.35E-15 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS26875 10370e6b66b218df67d3a6eebc8ba2b2 307 Pfam PF12834 Phage integrase, N-terminal 26 99 3.4E-17 T 13-09-2016 IPR024457 Putative integrase, N-terminal THL1_RS26875 10370e6b66b218df67d3a6eebc8ba2b2 307 Gene3D G3DSA:1.10.150.130 29 101 6.0E-6 T 13-09-2016 IPR023109 Integrase/recombinase, N-terminal THL1_RS26875 10370e6b66b218df67d3a6eebc8ba2b2 307 Pfam PF12835 Integrase 130 256 4.2E-16 T 13-09-2016 IPR024456 Integrase catalytic domain, putative THL1_RS26875 10370e6b66b218df67d3a6eebc8ba2b2 307 Gene3D G3DSA:1.10.443.10 139 257 1.7E-10 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS05885 f080806e51384b5d8d5431d5ddbff8f8 377 PANTHER PTHR21148 1 369 6.7E-175 T 13-09-2016 THL1_RS05885 f080806e51384b5d8d5431d5ddbff8f8 377 Pfam PF01702 Queuine tRNA-ribosyltransferase 132 365 9.3E-90 T 13-09-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS05885 f080806e51384b5d8d5431d5ddbff8f8 377 Gene3D G3DSA:3.20.20.105 5 369 7.1E-165 T 13-09-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS05885 f080806e51384b5d8d5431d5ddbff8f8 377 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 9 371 4.6E-167 T 13-09-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS05885 f080806e51384b5d8d5431d5ddbff8f8 377 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 7 363 56.521 T 13-09-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS05885 f080806e51384b5d8d5431d5ddbff8f8 377 PANTHER PTHR21148:SF26 1 369 6.7E-175 T 13-09-2016 THL1_RS05885 f080806e51384b5d8d5431d5ddbff8f8 377 SUPERFAMILY SSF51713 6 368 4.45E-161 T 13-09-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS05885 f080806e51384b5d8d5431d5ddbff8f8 377 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 9 370 5.9E-159 T 13-09-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS03650 dc1902ed211772cee35a2ac900a2494d 333 Gene3D G3DSA:3.30.1360.10 11 65 2.2E-9 T 13-09-2016 THL1_RS03650 dc1902ed211772cee35a2ac900a2494d 333 SUPERFAMILY SSF56553 53 177 3.4E-42 T 13-09-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03650 dc1902ed211772cee35a2ac900a2494d 333 SUPERFAMILY SSF47789 250 323 8.89E-26 T 13-09-2016 THL1_RS03650 dc1902ed211772cee35a2ac900a2494d 333 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 244 307 4.4E-24 T 13-09-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS03650 dc1902ed211772cee35a2ac900a2494d 333 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 29 227 5.1E-23 T 13-09-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS03650 dc1902ed211772cee35a2ac900a2494d 333 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 5 316 34.987 T 13-09-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS03650 dc1902ed211772cee35a2ac900a2494d 333 Gene3D G3DSA:1.10.150.20 244 326 9.0E-37 T 13-09-2016 THL1_RS03650 dc1902ed211772cee35a2ac900a2494d 333 Gene3D G3DSA:2.170.120.12 66 176 7.1E-42 T 13-09-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03650 dc1902ed211772cee35a2ac900a2494d 333 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 24 315 4.5E-109 T 13-09-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS03650 dc1902ed211772cee35a2ac900a2494d 333 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 64 155 4.2E-25 T 13-09-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03650 dc1902ed211772cee35a2ac900a2494d 333 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 255 328 1.0E-36 T 13-09-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS03650 dc1902ed211772cee35a2ac900a2494d 333 SUPERFAMILY SSF55257 6 53 7.36E-30 T 13-09-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS03650 dc1902ed211772cee35a2ac900a2494d 333 SUPERFAMILY SSF55257 178 232 7.36E-30 T 13-09-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS03650 dc1902ed211772cee35a2ac900a2494d 333 PANTHER PTHR32108 1 329 2.6E-152 T 13-09-2016 THL1_RS03650 dc1902ed211772cee35a2ac900a2494d 333 SMART SM00662 23 233 1.2E-106 T 13-09-2016 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03650 dc1902ed211772cee35a2ac900a2494d 333 PANTHER PTHR32108:SF0 1 329 2.6E-152 T 13-09-2016 THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 PANTHER PTHR24322 14 148 4.4E-66 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 PANTHER PTHR24322 164 196 4.4E-66 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 Pfam PF00106 short chain dehydrogenase 10 196 8.2E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 6.9E-8 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 6.9E-8 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 6.9E-8 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 Gene3D G3DSA:3.40.50.720 5 253 6.4E-67 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 PANTHER PTHR24322:SF482 14 148 4.4E-66 T 13-09-2016 THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 PANTHER PTHR24322:SF482 164 196 4.4E-66 T 13-09-2016 THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 184 3.1E-6 T 13-09-2016 THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 SUPERFAMILY SSF51735 5 251 5.57E-65 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.5E-25 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 1.5E-25 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.5E-25 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.5E-25 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.5E-25 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23560 a9d9c7a423cd25de886985b0dc2c4f7d 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.5E-25 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-09-2016 IPR031157 Tr-type G domain, conserved site THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 Pfam PF03144 Elongation factor Tu domain 2 228 296 2.5E-15 T 13-09-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 1.0E-33 T 13-09-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 Gene3D G3DSA:2.40.30.10 303 395 8.5E-47 T 13-09-2016 THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 SUPERFAMILY SSF50447 208 304 1.79E-29 T 13-09-2016 IPR009000 Translation protein, beta-barrel domain THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 1.1E-14 T 13-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 Gene3D G3DSA:2.40.30.10 215 301 6.6E-36 T 13-09-2016 THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 PANTHER PTHR23115:SF151 1 395 1.8E-275 T 13-09-2016 THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 59.717 T 13-09-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 Gene3D G3DSA:3.40.50.300 4 214 1.3E-65 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 204 6.9E-57 T 13-09-2016 THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.9E-24 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.9E-24 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.9E-24 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.9E-24 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.9E-24 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 PANTHER PTHR23115 1 395 1.8E-275 T 13-09-2016 THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 SUPERFAMILY SSF52540 6 222 6.64E-58 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 SUPERFAMILY SSF50465 301 396 3.74E-36 T 13-09-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal THL1_RS03450 1a87b334d30606aa1875a27f989577b3 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 6.9E-227 T 13-09-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 THL1_RS19535 29fb0dac885e97498dfa052faff6e16e 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 180 202 1.2E-28 T 13-09-2016 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 THL1_RS19535 29fb0dac885e97498dfa052faff6e16e 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 81 100 1.2E-28 T 13-09-2016 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 THL1_RS19535 29fb0dac885e97498dfa052faff6e16e 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 22 43 1.2E-28 T 13-09-2016 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 THL1_RS19535 29fb0dac885e97498dfa052faff6e16e 258 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 202 221 1.2E-28 T 13-09-2016 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 THL1_RS19535 29fb0dac885e97498dfa052faff6e16e 258 PANTHER PTHR30065:SF1 2 258 2.2E-91 T 13-09-2016 THL1_RS19535 29fb0dac885e97498dfa052faff6e16e 258 PANTHER PTHR30065 2 258 2.2E-91 T 13-09-2016 THL1_RS19535 29fb0dac885e97498dfa052faff6e16e 258 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 15 254 1.7E-78 T 13-09-2016 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 THL1_RS19535 29fb0dac885e97498dfa052faff6e16e 258 Pfam PF01311 Bacterial export proteins, family 1 15 243 9.3E-69 T 13-09-2016 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 THL1_RS25385 43d3446bf07e3eb8ce2a9b8e94f1440e 1635 PANTHER PTHR11412:SF104 243 939 1.5E-182 T 13-09-2016 THL1_RS25385 43d3446bf07e3eb8ce2a9b8e94f1440e 1635 Pfam PF10569 Alpha-macro-globulin thiol-ester bond-forming region 1163 1181 2.0E-5 T 13-09-2016 IPR019565 Alpha-2-macroglobulin, thiol-ester bond-forming THL1_RS25385 43d3446bf07e3eb8ce2a9b8e94f1440e 1635 PIRSF PIRSF038980 4 1635 0.0 T 13-09-2016 IPR026284 Alpha-2-macroglobulin domain protein, bacteria THL1_RS25385 43d3446bf07e3eb8ce2a9b8e94f1440e 1635 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 280 373 1.3E-20 T 13-09-2016 IPR021868 Alpha-2-macroglobulin MG1 domain THL1_RS25385 43d3446bf07e3eb8ce2a9b8e94f1440e 1635 Pfam PF00207 Alpha-2-macroglobulin family 956 1034 2.3E-7 T 13-09-2016 IPR001599 Alpha-2-macroglobulin GO:0004866 THL1_RS25385 43d3446bf07e3eb8ce2a9b8e94f1440e 1635 SMART SM01360 946 1035 2.0E-23 T 13-09-2016 IPR001599 Alpha-2-macroglobulin GO:0004866 THL1_RS25385 43d3446bf07e3eb8ce2a9b8e94f1440e 1635 Pfam PF01835 MG2 domain 379 471 2.2E-21 T 13-09-2016 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 THL1_RS25385 43d3446bf07e3eb8ce2a9b8e94f1440e 1635 Pfam PF07678 A-macroglobulin complement component 1207 1266 1.0E-4 T 13-09-2016 IPR011626 Alpha-macroglobulin complement component GO:0005615 THL1_RS25385 43d3446bf07e3eb8ce2a9b8e94f1440e 1635 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 737 884 1.0E-11 T 13-09-2016 IPR011625 Alpha-2-macroglobulin, N-terminal 2 THL1_RS25385 43d3446bf07e3eb8ce2a9b8e94f1440e 1635 Gene3D G3DSA:1.50.10.20 1156 1409 3.8E-38 T 13-09-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid THL1_RS25385 43d3446bf07e3eb8ce2a9b8e94f1440e 1635 SUPERFAMILY SSF48239 1156 1412 3.93E-43 T 13-09-2016 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid THL1_RS25385 43d3446bf07e3eb8ce2a9b8e94f1440e 1635 SMART SM01359 736 884 1.4E-36 T 13-09-2016 IPR011625 Alpha-2-macroglobulin, N-terminal 2 THL1_RS25385 43d3446bf07e3eb8ce2a9b8e94f1440e 1635 PANTHER PTHR11412 243 939 1.5E-182 T 13-09-2016 THL1_RS09185 9db2e2cca8b036d8c7d1d8561592ba02 351 PANTHER PTHR11863 141 287 3.0E-18 T 13-09-2016 THL1_RS09185 9db2e2cca8b036d8c7d1d8561592ba02 351 PANTHER PTHR11863:SF2 141 287 3.0E-18 T 13-09-2016 THL1_RS09185 9db2e2cca8b036d8c7d1d8561592ba02 351 Pfam PF04116 Fatty acid hydroxylase superfamily 141 286 1.3E-27 T 13-09-2016 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 THL1_RS27545 a9473699da201817173529462d88b918 300 Gene3D G3DSA:3.30.230.10 5 167 3.8E-33 T 13-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THL1_RS27545 a9473699da201817173529462d88b918 300 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 6 297 4.2E-112 T 13-09-2016 IPR004482 Mg chelatase-related protein THL1_RS27545 a9473699da201817173529462d88b918 300 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 9.0E-46 T 13-09-2016 THL1_RS27545 a9473699da201817173529462d88b918 300 Pfam PF01078 Magnesium chelatase, subunit ChlI 190 297 7.3E-46 T 13-09-2016 IPR000523 Magnesium chelatase ChlI domain THL1_RS27545 a9473699da201817173529462d88b918 300 SUPERFAMILY SSF54211 8 169 6.83E-35 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS27545 a9473699da201817173529462d88b918 300 PANTHER PTHR32039:SF7 1 297 1.0E-143 T 13-09-2016 IPR004482 Mg chelatase-related protein THL1_RS27545 a9473699da201817173529462d88b918 300 SUPERFAMILY SSF52540 188 297 4.54E-17 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27545 a9473699da201817173529462d88b918 300 PANTHER PTHR32039 1 297 1.0E-143 T 13-09-2016 THL1_RS27545 a9473699da201817173529462d88b918 300 Gene3D G3DSA:3.40.50.300 189 297 2.2E-24 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01835 e58ef994a1e253a58df994a769ccd08e 312 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 30 283 1.8E-56 T 13-09-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 THL1_RS01835 e58ef994a1e253a58df994a769ccd08e 312 PANTHER PTHR30177 16 287 1.9E-111 T 13-09-2016 THL1_RS01835 e58ef994a1e253a58df994a769ccd08e 312 TIGRFAM TIGR03414 ABC_choline_bnd: choline ABC transporter, periplasmic binding protein 21 307 3.9E-129 T 13-09-2016 IPR017783 ABC transporter, choline, substrate-binding protein GO:0015871|GO:0033265|GO:0042597 THL1_RS01835 e58ef994a1e253a58df994a769ccd08e 312 PANTHER PTHR30177:SF6 16 287 1.9E-111 T 13-09-2016 THL1_RS01835 e58ef994a1e253a58df994a769ccd08e 312 Gene3D G3DSA:3.40.190.10 237 299 6.2E-33 T 13-09-2016 THL1_RS01835 e58ef994a1e253a58df994a769ccd08e 312 Gene3D G3DSA:3.40.190.10 24 108 6.2E-33 T 13-09-2016 THL1_RS01835 e58ef994a1e253a58df994a769ccd08e 312 Gene3D G3DSA:3.40.190.100 117 236 7.0E-24 T 13-09-2016 THL1_RS01835 e58ef994a1e253a58df994a769ccd08e 312 SUPERFAMILY SSF53850 23 299 1.41E-76 T 13-09-2016 THL1_RS02180 4865a65f3f91259c4f72d9b5fb03f648 271 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 23 269 5.2E-74 T 13-09-2016 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519|UniPathway: UPA00078 THL1_RS02180 4865a65f3f91259c4f72d9b5fb03f648 271 PANTHER PTHR10108:SF855 24 194 2.5E-41 T 13-09-2016 THL1_RS02180 4865a65f3f91259c4f72d9b5fb03f648 271 SUPERFAMILY SSF53335 21 204 1.04E-39 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS02180 4865a65f3f91259c4f72d9b5fb03f648 271 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 15 269 31.219 T 13-09-2016 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00670+2.1.1.19|KEGG: 00780+2.1.1.197|MetaCyc: PWY-2201|MetaCyc: PWY-6519|UniPathway: UPA00078 THL1_RS02180 4865a65f3f91259c4f72d9b5fb03f648 271 Pfam PF08241 Methyltransferase domain 59 152 2.7E-20 T 13-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 THL1_RS02180 4865a65f3f91259c4f72d9b5fb03f648 271 PANTHER PTHR10108 24 194 2.5E-41 T 13-09-2016 THL1_RS02180 4865a65f3f91259c4f72d9b5fb03f648 271 Gene3D G3DSA:3.40.50.150 19 197 3.6E-36 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Gene3D G3DSA:3.30.450.20 1219 1325 1.4E-36 T 13-09-2016 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Pfam PF13188 PAS domain 1100 1148 3.3E-4 T 13-09-2016 IPR000014 PAS domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Pfam PF08447 PAS fold 518 587 1.7E-8 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Pfam PF13426 PAS domain 1219 1324 5.3E-22 T 13-09-2016 IPR000014 PAS domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Pfam PF13185 GAF domain 629 770 2.1E-11 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Gene3D G3DSA:3.30.450.20 1091 1198 4.5E-9 T 13-09-2016 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Pfam PF08448 PAS fold 793 896 5.6E-8 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SUPERFAMILY SSF55785 488 603 1.4E-17 T 13-09-2016 IPR000014 PAS domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Gene3D G3DSA:3.30.450.20 492 603 7.9E-19 T 13-09-2016 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Gene3D G3DSA:3.30.450.20 779 892 8.0E-20 T 13-09-2016 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SUPERFAMILY SSF141868 1513 1763 6.8E-92 T 13-09-2016 IPR001633 EAL domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 PANTHER PTHR10799:SF774 1190 1587 9.6E-68 T 13-09-2016 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 PANTHER PTHR10799:SF774 1881 1900 9.6E-68 T 13-09-2016 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SMART SM00052 1507 1753 1.3E-115 T 13-09-2016 IPR001633 EAL domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SUPERFAMILY SSF52172 1778 1895 1.71E-27 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SMART SM00086 1283 1325 7.1E-13 T 13-09-2016 IPR001610 PAC motif THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SMART SM00086 567 605 14.0 T 13-09-2016 IPR001610 PAC motif THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SMART SM00086 854 895 17.0 T 13-09-2016 IPR001610 PAC motif THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 PANTHER PTHR10799 1881 1900 9.6E-68 T 13-09-2016 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 PANTHER PTHR10799 27 221 9.6E-68 T 13-09-2016 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1333 1495 2.2E-44 T 13-09-2016 IPR000160 GGDEF domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Gene3D G3DSA:3.20.20.450 1511 1761 1.5E-97 T 13-09-2016 IPR001633 EAL domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SMART SM00267 1325 1497 5.8E-68 T 13-09-2016 IPR000160 GGDEF domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SMART SM00091 1208 1277 2.5E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SMART SM00091 495 561 4.7E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SMART SM00091 783 849 1.0E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SMART SM00091 1096 1162 0.014 T 13-09-2016 IPR000014 PAS domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SMART SM00065 623 779 3.3E-6 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SMART SM00065 931 1085 4.9E-7 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Gene3D G3DSA:3.30.450.40 906 1086 4.6E-16 T 13-09-2016 IPR029016 GAF domain-like THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Gene3D G3DSA:3.30.450.40 613 778 7.4E-19 T 13-09-2016 IPR029016 GAF domain-like THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SUPERFAMILY SSF55785 1088 1198 4.47E-9 T 13-09-2016 IPR000014 PAS domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SMART SM00448 1779 1891 8.8E-22 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Pfam PF01590 GAF domain 933 1075 4.0E-6 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SUPERFAMILY SSF55785 770 892 1.44E-19 T 13-09-2016 IPR000014 PAS domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 PANTHER PTHR10799:SF774 27 221 9.6E-68 T 13-09-2016 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Gene3D G3DSA:3.30.70.270 1338 1505 5.5E-59 T 13-09-2016 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Pfam PF00072 Response regulator receiver domain 1782 1891 1.1E-19 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SUPERFAMILY SSF55781 598 771 1.55E-26 T 13-09-2016 IPR029016 GAF domain-like THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1336 1492 9.3E-50 T 13-09-2016 IPR000160 GGDEF domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 PANTHER PTHR10799 1190 1587 9.6E-68 T 13-09-2016 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 1205 1332 2.7E-21 T 13-09-2016 IPR000014 PAS domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 779 901 2.4E-15 T 13-09-2016 IPR000014 PAS domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 499 605 4.2E-14 T 13-09-2016 IPR000014 PAS domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Pfam PF00563 EAL domain 1513 1748 7.3E-75 T 13-09-2016 IPR001633 EAL domain THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SUPERFAMILY SSF55073 1341 1499 1.49E-50 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 Gene3D G3DSA:3.40.50.2300 1780 1901 1.2E-27 T 13-09-2016 THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SUPERFAMILY SSF55781 913 1101 8.29E-18 T 13-09-2016 IPR029016 GAF domain-like THL1_RS02880 67996cc981d7faad230a5e031dc1e133 1909 SUPERFAMILY SSF55785 1215 1325 6.02E-30 T 13-09-2016 IPR000014 PAS domain THL1_RS06930 9a1afd5ec2961c687cfe44c8258af57e 495 SUPERFAMILY SSF52540 302 482 2.42E-25 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06930 9a1afd5ec2961c687cfe44c8258af57e 495 SUPERFAMILY SSF52540 41 217 2.13E-14 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06930 9a1afd5ec2961c687cfe44c8258af57e 495 Gene3D G3DSA:3.40.50.300 1 244 3.9E-83 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06930 9a1afd5ec2961c687cfe44c8258af57e 495 Gene3D G3DSA:3.40.50.300 251 492 2.0E-103 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06930 9a1afd5ec2961c687cfe44c8258af57e 495 PANTHER PTHR34383:SF3 4 489 8.1E-280 T 13-09-2016 THL1_RS06930 9a1afd5ec2961c687cfe44c8258af57e 495 PANTHER PTHR34383 4 489 8.1E-280 T 13-09-2016 THL1_RS06930 9a1afd5ec2961c687cfe44c8258af57e 495 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 269 491 2.3E-94 T 13-09-2016 IPR022488 Polyphosphate kinase-2-related THL1_RS06930 9a1afd5ec2961c687cfe44c8258af57e 495 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 11 237 1.4E-52 T 13-09-2016 IPR022488 Polyphosphate kinase-2-related THL1_RS06930 9a1afd5ec2961c687cfe44c8258af57e 495 TIGRFAM TIGR03708 poly_P_AMP_trns: polyphosphate:AMP phosphotransferase 2 491 4.3E-230 T 13-09-2016 IPR022489 Polyphosphate:AMP phosphotransferase GO:0006797|GO:0043751 THL1_RS10950 1f0fe7d2a2a5ea726c02e0e441dd9c92 286 PIRSF PIRSF006232 1 281 7.3E-80 T 13-09-2016 IPR012093 Pirin THL1_RS10950 1f0fe7d2a2a5ea726c02e0e441dd9c92 286 PANTHER PTHR13903 20 286 6.2E-92 T 13-09-2016 IPR012093 Pirin THL1_RS10950 1f0fe7d2a2a5ea726c02e0e441dd9c92 286 Pfam PF05726 Pirin C-terminal cupin domain 174 270 1.6E-17 T 13-09-2016 IPR008778 Pirin, C-terminal domain THL1_RS10950 1f0fe7d2a2a5ea726c02e0e441dd9c92 286 SUPERFAMILY SSF51182 5 283 4.58E-72 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS10950 1f0fe7d2a2a5ea726c02e0e441dd9c92 286 PANTHER PTHR13903:SF4 20 286 6.2E-92 T 13-09-2016 THL1_RS10950 1f0fe7d2a2a5ea726c02e0e441dd9c92 286 Gene3D G3DSA:2.60.120.10 9 245 1.6E-62 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS10950 1f0fe7d2a2a5ea726c02e0e441dd9c92 286 Pfam PF02678 Pirin 23 121 7.7E-32 T 13-09-2016 IPR003829 Pirin, N-terminal domain THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 Pfam PF00813 FliP family 52 244 3.3E-79 T 13-09-2016 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 177 192 - T 13-09-2016 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 PANTHER PTHR30587:SF0 26 250 6.5E-124 T 13-09-2016 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 148 160 1.3E-23 T 13-09-2016 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 48 57 1.3E-23 T 13-09-2016 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 170 182 1.3E-23 T 13-09-2016 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 120 134 1.3E-23 T 13-09-2016 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 108 120 1.3E-23 T 13-09-2016 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 238 248 1.3E-23 T 13-09-2016 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 225 237 - T 13-09-2016 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 52 248 6.3E-88 T 13-09-2016 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 89 108 5.4E-67 T 13-09-2016 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 50 69 5.4E-67 T 13-09-2016 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 177 197 5.4E-67 T 13-09-2016 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 222 247 5.4E-67 T 13-09-2016 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 198 219 5.4E-67 T 13-09-2016 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 69 89 5.4E-67 T 13-09-2016 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 THL1_RS19545 1dd1586d9205a29e17dfd066f7bf006a 251 PANTHER PTHR30587 26 250 6.5E-124 T 13-09-2016 THL1_RS25005 3c00a153fd7037e38aa512b48b10f8c9 401 PANTHER PTHR30012 2 401 6.3E-193 T 13-09-2016 THL1_RS25005 3c00a153fd7037e38aa512b48b10f8c9 401 PANTHER PTHR30012:SF6 2 401 6.3E-193 T 13-09-2016 THL1_RS25005 3c00a153fd7037e38aa512b48b10f8c9 401 PRINTS PR00812 Bacterial general secretion pathway protein F signature 162 190 3.1E-33 T 13-09-2016 IPR003004 GspF/PilC family THL1_RS25005 3c00a153fd7037e38aa512b48b10f8c9 401 PRINTS PR00812 Bacterial general secretion pathway protein F signature 381 400 3.1E-33 T 13-09-2016 IPR003004 GspF/PilC family THL1_RS25005 3c00a153fd7037e38aa512b48b10f8c9 401 PRINTS PR00812 Bacterial general secretion pathway protein F signature 63 75 3.1E-33 T 13-09-2016 IPR003004 GspF/PilC family THL1_RS25005 3c00a153fd7037e38aa512b48b10f8c9 401 PRINTS PR00812 Bacterial general secretion pathway protein F signature 365 379 3.1E-33 T 13-09-2016 IPR003004 GspF/PilC family THL1_RS25005 3c00a153fd7037e38aa512b48b10f8c9 401 Pfam PF00482 Type II secretion system (T2SS), protein F 270 392 8.1E-30 T 13-09-2016 IPR018076 Type II secretion system F domain THL1_RS25005 3c00a153fd7037e38aa512b48b10f8c9 401 Pfam PF00482 Type II secretion system (T2SS), protein F 68 190 7.4E-26 T 13-09-2016 IPR018076 Type II secretion system F domain THL1_RS25005 3c00a153fd7037e38aa512b48b10f8c9 401 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 162 190 - T 13-09-2016 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 THL1_RS25005 3c00a153fd7037e38aa512b48b10f8c9 401 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 400 5.5E-140 T 13-09-2016 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 THL1_RS10450 648c5d6726a1aef043768096524dc44c 260 ProDom PD037484 CAPSID DETERMINATION SIZE HEAD GLYCOPROTEIN SID MORPHOGENESIS CP-933I ENCODED LATE 1 103 4.0E-4 T 13-09-2016 THL1_RS24540 235dbe95beb22e39fbd2fbaf4a6330d3 381 Hamap MF_01559 L-lactate dehydrogenase [lldD]. 1 380 74.646 T 13-09-2016 IPR020920 L-lactate dehydrogenase, bacterial GO:0004457|GO:0006089|GO:0010181|GO:0055114 THL1_RS24540 235dbe95beb22e39fbd2fbaf4a6330d3 381 PIRSF PIRSF000138 2 379 6.1E-123 T 13-09-2016 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 THL1_RS24540 235dbe95beb22e39fbd2fbaf4a6330d3 381 Gene3D G3DSA:3.20.20.70 7 376 1.5E-133 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS24540 235dbe95beb22e39fbd2fbaf4a6330d3 381 SUPERFAMILY SSF51395 223 374 8.55E-99 T 13-09-2016 THL1_RS24540 235dbe95beb22e39fbd2fbaf4a6330d3 381 SUPERFAMILY SSF51395 7 193 8.55E-99 T 13-09-2016 THL1_RS24540 235dbe95beb22e39fbd2fbaf4a6330d3 381 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 273 279 - T 13-09-2016 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 THL1_RS24540 235dbe95beb22e39fbd2fbaf4a6330d3 381 Pfam PF01070 FMN-dependent dehydrogenase 13 375 1.7E-125 T 13-09-2016 IPR000262 FMN-dependent dehydrogenase GO:0016491 THL1_RS24540 235dbe95beb22e39fbd2fbaf4a6330d3 381 PANTHER PTHR10578:SF65 7 378 8.6E-163 T 13-09-2016 THL1_RS24540 235dbe95beb22e39fbd2fbaf4a6330d3 381 PANTHER PTHR10578 7 378 8.6E-163 T 13-09-2016 THL1_RS03925 d24aa731adf35e72dfd0629d83eabe46 295 PANTHER PTHR12001:SF23 2 290 3.1E-107 T 13-09-2016 THL1_RS03925 d24aa731adf35e72dfd0629d83eabe46 295 Gene3D G3DSA:1.10.600.10 3 293 3.8E-94 T 13-09-2016 IPR008949 Isoprenoid synthase domain THL1_RS03925 d24aa731adf35e72dfd0629d83eabe46 295 PANTHER PTHR12001 2 290 3.1E-107 T 13-09-2016 IPR017446 Polyprenyl synthetase-related THL1_RS03925 d24aa731adf35e72dfd0629d83eabe46 295 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 214 226 - T 13-09-2016 IPR000092 Polyprenyl synthetase GO:0008299 THL1_RS03925 d24aa731adf35e72dfd0629d83eabe46 295 SUPERFAMILY SSF48576 4 288 6.0E-86 T 13-09-2016 IPR008949 Isoprenoid synthase domain THL1_RS03925 d24aa731adf35e72dfd0629d83eabe46 295 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 80 96 - T 13-09-2016 IPR000092 Polyprenyl synthetase GO:0008299 THL1_RS03925 d24aa731adf35e72dfd0629d83eabe46 295 Pfam PF00348 Polyprenyl synthetase 30 270 1.7E-55 T 13-09-2016 IPR000092 Polyprenyl synthetase GO:0008299 THL1_RS25730 801343d18722a83125f3fafd4eb2c5ad 123 Pfam PF04134 Protein of unknown function, DUF393 9 118 1.9E-19 T 13-09-2016 IPR007263 Protein of unknown function DUF393 THL1_RS17065 b604298dba75d77f1025f6f9572809a3 617 SUPERFAMILY SSF52402 462 586 5.91E-62 T 13-09-2016 THL1_RS17065 b604298dba75d77f1025f6f9572809a3 617 SUPERFAMILY SSF52402 231 400 5.91E-62 T 13-09-2016 THL1_RS17065 b604298dba75d77f1025f6f9572809a3 617 Pfam PF00733 Asparagine synthase 242 608 1.6E-84 T 13-09-2016 IPR001962 Asparagine synthase GO:0004066|GO:0006529 THL1_RS17065 b604298dba75d77f1025f6f9572809a3 617 Pfam PF13537 Glutamine amidotransferase domain 48 171 7.2E-46 T 13-09-2016 IPR017932 Glutamine amidotransferase type 2 domain THL1_RS17065 b604298dba75d77f1025f6f9572809a3 617 PIRSF PIRSF001589 1 616 8.0E-141 T 13-09-2016 THL1_RS17065 b604298dba75d77f1025f6f9572809a3 617 PANTHER PTHR11772 451 617 4.0E-202 T 13-09-2016 THL1_RS17065 b604298dba75d77f1025f6f9572809a3 617 PANTHER PTHR11772 2 402 4.0E-202 T 13-09-2016 THL1_RS17065 b604298dba75d77f1025f6f9572809a3 617 Gene3D G3DSA:3.40.50.620 226 404 3.0E-73 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS17065 b604298dba75d77f1025f6f9572809a3 617 Gene3D G3DSA:3.40.50.620 466 585 3.0E-73 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS17065 b604298dba75d77f1025f6f9572809a3 617 SUPERFAMILY SSF56235 1 226 8.49E-62 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS17065 b604298dba75d77f1025f6f9572809a3 617 PANTHER PTHR11772:SF7 451 617 4.0E-202 T 13-09-2016 THL1_RS17065 b604298dba75d77f1025f6f9572809a3 617 PANTHER PTHR11772:SF7 2 402 4.0E-202 T 13-09-2016 THL1_RS17065 b604298dba75d77f1025f6f9572809a3 617 Gene3D G3DSA:3.60.20.10 1 225 1.9E-74 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS17065 b604298dba75d77f1025f6f9572809a3 617 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 542 8.4E-149 T 13-09-2016 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|UniPathway: UPA00134 THL1_RS05850 ba899c7d3f90b5cd594d52bcea40b342 495 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 19 147 3.0E-32 T 13-09-2016 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 THL1_RS05850 ba899c7d3f90b5cd594d52bcea40b342 495 PANTHER PTHR11963 11 495 5.3E-226 T 13-09-2016 THL1_RS05850 ba899c7d3f90b5cd594d52bcea40b342 495 PANTHER PTHR11963:SF13 11 495 5.3E-226 T 13-09-2016 THL1_RS05850 ba899c7d3f90b5cd594d52bcea40b342 495 PRINTS PR00481 Cytosol aminopeptidase signature 320 341 3.4E-54 T 13-09-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THL1_RS05850 ba899c7d3f90b5cd594d52bcea40b342 495 PRINTS PR00481 Cytosol aminopeptidase signature 261 278 3.4E-54 T 13-09-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THL1_RS05850 ba899c7d3f90b5cd594d52bcea40b342 495 PRINTS PR00481 Cytosol aminopeptidase signature 370 385 3.4E-54 T 13-09-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THL1_RS05850 ba899c7d3f90b5cd594d52bcea40b342 495 PRINTS PR00481 Cytosol aminopeptidase signature 342 362 3.4E-54 T 13-09-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THL1_RS05850 ba899c7d3f90b5cd594d52bcea40b342 495 PRINTS PR00481 Cytosol aminopeptidase signature 283 304 3.4E-54 T 13-09-2016 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THL1_RS05850 ba899c7d3f90b5cd594d52bcea40b342 495 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 346 353 - T 13-09-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 THL1_RS05850 ba899c7d3f90b5cd594d52bcea40b342 495 Gene3D G3DSA:3.40.220.10 1 160 8.2E-58 T 13-09-2016 THL1_RS05850 ba899c7d3f90b5cd594d52bcea40b342 495 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 495 40.816 T 13-09-2016 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 THL1_RS05850 ba899c7d3f90b5cd594d52bcea40b342 495 SUPERFAMILY SSF53187 177 493 4.71E-126 T 13-09-2016 THL1_RS05850 ba899c7d3f90b5cd594d52bcea40b342 495 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 184 486 7.2E-122 T 13-09-2016 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 THL1_RS05850 ba899c7d3f90b5cd594d52bcea40b342 495 Gene3D G3DSA:3.40.630.10 177 493 3.4E-141 T 13-09-2016 THL1_RS05850 ba899c7d3f90b5cd594d52bcea40b342 495 SUPERFAMILY SSF52949 1 182 5.89E-47 T 13-09-2016 THL1_RS01310 a48bf6c52b96616007b777fb1a297cdc 344 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS01310 a48bf6c52b96616007b777fb1a297cdc 344 Pfam PF00437 Type II/IV secretion system protein 11 267 6.9E-46 T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS01310 a48bf6c52b96616007b777fb1a297cdc 344 PANTHER PTHR30486 1 344 1.1E-199 T 13-09-2016 THL1_RS01310 a48bf6c52b96616007b777fb1a297cdc 344 Gene3D G3DSA:3.40.50.300 100 343 3.4E-69 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01310 a48bf6c52b96616007b777fb1a297cdc 344 SMART SM00382 122 256 0.0028 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS01310 a48bf6c52b96616007b777fb1a297cdc 344 SUPERFAMILY SSF52540 5 335 6.08E-72 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01310 a48bf6c52b96616007b777fb1a297cdc 344 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 342 3.0E-152 T 13-09-2016 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 THL1_RS01310 a48bf6c52b96616007b777fb1a297cdc 344 PANTHER PTHR30486:SF6 1 344 1.1E-199 T 13-09-2016 THL1_RS14290 94860488ec2f94beb2289474b2e7431a 445 Gene3D G3DSA:3.40.50.2300 323 442 3.5E-21 T 13-09-2016 THL1_RS14290 94860488ec2f94beb2289474b2e7431a 445 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 194 302 3.1E-19 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS14290 94860488ec2f94beb2289474b2e7431a 445 Gene3D G3DSA:3.30.565.10 152 307 3.5E-35 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS14290 94860488ec2f94beb2289474b2e7431a 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 287 300 4.8E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS14290 94860488ec2f94beb2289474b2e7431a 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 228 242 4.8E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS14290 94860488ec2f94beb2289474b2e7431a 445 PRINTS PR00344 Bacterial sensor protein C-terminal signature 263 281 4.8E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS14290 94860488ec2f94beb2289474b2e7431a 445 PANTHER PTHR24423:SF439 61 441 6.6E-126 T 13-09-2016 THL1_RS14290 94860488ec2f94beb2289474b2e7431a 445 Pfam PF00512 His Kinase A (phospho-acceptor) domain 83 147 1.4E-9 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS14290 94860488ec2f94beb2289474b2e7431a 445 Pfam PF00072 Response regulator receiver domain 328 437 5.3E-14 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS14290 94860488ec2f94beb2289474b2e7431a 445 SUPERFAMILY SSF52172 324 442 3.56E-22 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS14290 94860488ec2f94beb2289474b2e7431a 445 SUPERFAMILY SSF47384 66 146 3.53E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS14290 94860488ec2f94beb2289474b2e7431a 445 Gene3D G3DSA:1.10.287.130 77 144 5.3E-8 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS14290 94860488ec2f94beb2289474b2e7431a 445 PANTHER PTHR24423 61 441 6.6E-126 T 13-09-2016 THL1_RS14290 94860488ec2f94beb2289474b2e7431a 445 SUPERFAMILY SSF55874 138 304 1.83E-35 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS14290 94860488ec2f94beb2289474b2e7431a 445 SMART SM00387 192 303 1.3E-26 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS14290 94860488ec2f94beb2289474b2e7431a 445 SMART SM00448 325 437 7.5E-12 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS14290 94860488ec2f94beb2289474b2e7431a 445 SMART SM00388 83 148 1.1E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS02955 27bfc2382405218d18a72c520f9609a6 502 Gene3D G3DSA:3.40.50.150 77 268 5.9E-49 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS02955 27bfc2382405218d18a72c520f9609a6 502 SMART SM00138 8 281 7.4E-38 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS02955 27bfc2382405218d18a72c520f9609a6 502 SUPERFAMILY SSF53335 77 261 8.81E-38 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS02955 27bfc2382405218d18a72c520f9609a6 502 PRINTS PR00996 Glutamate methyltransferase family signature 148 164 9.6E-17 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS02955 27bfc2382405218d18a72c520f9609a6 502 PRINTS PR00996 Glutamate methyltransferase family signature 112 132 9.6E-17 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS02955 27bfc2382405218d18a72c520f9609a6 502 PRINTS PR00996 Glutamate methyltransferase family signature 239 262 9.6E-17 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS02955 27bfc2382405218d18a72c520f9609a6 502 PRINTS PR00996 Glutamate methyltransferase family signature 220 234 9.6E-17 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS02955 27bfc2382405218d18a72c520f9609a6 502 Gene3D G3DSA:1.25.40.10 355 466 2.6E-13 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS02955 27bfc2382405218d18a72c520f9609a6 502 PANTHER PTHR24422 18 261 4.2E-41 T 13-09-2016 THL1_RS02955 27bfc2382405218d18a72c520f9609a6 502 SUPERFAMILY SSF48452 372 462 4.85E-12 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS02955 27bfc2382405218d18a72c520f9609a6 502 Pfam PF01739 CheR methyltransferase, SAM binding domain 78 260 6.1E-38 T 13-09-2016 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal THL1_RS02955 27bfc2382405218d18a72c520f9609a6 502 PANTHER PTHR24422:SF14 18 261 4.2E-41 T 13-09-2016 THL1_RS24545 bfc0c4e47c474439cf8ce1feacf965c9 937 Gene3D G3DSA:3.30.465.10 98 264 1.2E-18 T 13-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THL1_RS24545 bfc0c4e47c474439cf8ce1feacf965c9 937 Pfam PF12838 4Fe-4S dicluster domain 539 608 8.3E-10 T 13-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THL1_RS24545 bfc0c4e47c474439cf8ce1feacf965c9 937 SUPERFAMILY SSF46548 493 620 1.71E-21 T 13-09-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 THL1_RS24545 bfc0c4e47c474439cf8ce1feacf965c9 937 SUPERFAMILY SSF55103 269 521 1.49E-56 T 13-09-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 THL1_RS24545 bfc0c4e47c474439cf8ce1feacf965c9 937 Pfam PF01565 FAD binding domain 41 177 6.5E-33 T 13-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THL1_RS24545 bfc0c4e47c474439cf8ce1feacf965c9 937 Gene3D G3DSA:1.10.45.10 476 505 5.1E-8 T 13-09-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 THL1_RS24545 bfc0c4e47c474439cf8ce1feacf965c9 937 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 540 551 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS24545 bfc0c4e47c474439cf8ce1feacf965c9 937 Pfam PF02913 FAD linked oxidases, C-terminal domain 267 513 5.5E-58 T 13-09-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 THL1_RS24545 bfc0c4e47c474439cf8ce1feacf965c9 937 PANTHER PTHR11748 220 562 1.5E-288 T 13-09-2016 THL1_RS24545 bfc0c4e47c474439cf8ce1feacf965c9 937 PANTHER PTHR11748 6 181 1.5E-288 T 13-09-2016 THL1_RS24545 bfc0c4e47c474439cf8ce1feacf965c9 937 SUPERFAMILY SSF56176 7 264 4.5E-55 T 13-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THL1_RS24545 bfc0c4e47c474439cf8ce1feacf965c9 937 Gene3D G3DSA:1.10.1060.10 506 622 1.3E-18 T 13-09-2016 THL1_RS24545 bfc0c4e47c474439cf8ce1feacf965c9 937 Gene3D G3DSA:3.30.43.10 7 89 5.5E-12 T 13-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 THL1_RS24545 bfc0c4e47c474439cf8ce1feacf965c9 937 Pfam PF02754 Cysteine-rich domain 833 893 0.057 T 13-09-2016 IPR004017 Cysteine-rich domain THL1_RS24545 bfc0c4e47c474439cf8ce1feacf965c9 937 Pfam PF02754 Cysteine-rich domain 728 795 0.027 T 13-09-2016 IPR004017 Cysteine-rich domain THL1_RS24545 bfc0c4e47c474439cf8ce1feacf965c9 937 PANTHER PTHR11748:SF65 220 562 1.5E-288 T 13-09-2016 THL1_RS24545 bfc0c4e47c474439cf8ce1feacf965c9 937 PANTHER PTHR11748:SF65 6 181 1.5E-288 T 13-09-2016 THL1_RS01840 f14cab6a1cbf6c6ba0622878a3b1ecc8 294 PANTHER PTHR37418 107 294 5.9E-151 T 13-09-2016 THL1_RS01840 f14cab6a1cbf6c6ba0622878a3b1ecc8 294 Pfam PF05853 beta-keto acid cleavage enzyme 5 291 4.9E-98 T 13-09-2016 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00600+2.3.1.24|UniPathway: UPA00870 THL1_RS01840 f14cab6a1cbf6c6ba0622878a3b1ecc8 294 Gene3D G3DSA:3.20.20.70 4 293 3.3E-112 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS01840 f14cab6a1cbf6c6ba0622878a3b1ecc8 294 PANTHER PTHR37418:SF2 107 294 5.9E-151 T 13-09-2016 THL1_RS01840 f14cab6a1cbf6c6ba0622878a3b1ecc8 294 PANTHER PTHR37418:SF2 2 88 5.9E-151 T 13-09-2016 THL1_RS01840 f14cab6a1cbf6c6ba0622878a3b1ecc8 294 PANTHER PTHR37418 2 88 5.9E-151 T 13-09-2016 THL1_RS22150 d73e5c4af2124f1a222b27b49708fb4f 156 PANTHER PTHR30295:SF6 1 154 4.9E-67 T 13-09-2016 THL1_RS22150 d73e5c4af2124f1a222b27b49708fb4f 156 SUPERFAMILY SSF47240 5 155 5.98E-47 T 13-09-2016 IPR009078 Ferritin-like superfamily THL1_RS22150 d73e5c4af2124f1a222b27b49708fb4f 156 PANTHER PTHR30295 1 154 4.9E-67 T 13-09-2016 THL1_RS22150 d73e5c4af2124f1a222b27b49708fb4f 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 61 77 2.8E-11 T 13-09-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 THL1_RS22150 d73e5c4af2124f1a222b27b49708fb4f 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 37 53 2.8E-11 T 13-09-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 THL1_RS22150 d73e5c4af2124f1a222b27b49708fb4f 156 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 132 150 2.8E-11 T 13-09-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 THL1_RS22150 d73e5c4af2124f1a222b27b49708fb4f 156 Gene3D G3DSA:1.20.1260.10 2 155 2.0E-66 T 13-09-2016 IPR012347 Ferritin-related THL1_RS22150 d73e5c4af2124f1a222b27b49708fb4f 156 PIRSF PIRSF005900 1 156 2.4E-46 T 13-09-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 THL1_RS22150 d73e5c4af2124f1a222b27b49708fb4f 156 ProSitePatterns PS00819 Dps protein family signature 2. 63 77 - T 13-09-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 THL1_RS22150 d73e5c4af2124f1a222b27b49708fb4f 156 Pfam PF00210 Ferritin-like domain 17 155 1.7E-27 T 13-09-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 THL1_RS22150 d73e5c4af2124f1a222b27b49708fb4f 156 ProSitePatterns PS00818 Dps protein family signature 1. 37 53 - T 13-09-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 THL1_RS17120 be928b8f4a7d9c04eb312e2630f6c3f5 495 Gene3D G3DSA:1.10.405.10 157 233 1.1E-18 T 13-09-2016 THL1_RS17120 be928b8f4a7d9c04eb312e2630f6c3f5 495 SUPERFAMILY SSF51905 447 488 1.14E-60 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS17120 be928b8f4a7d9c04eb312e2630f6c3f5 495 SUPERFAMILY SSF51905 51 349 1.14E-60 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS17120 be928b8f4a7d9c04eb312e2630f6c3f5 495 Pfam PF01593 Flavin containing amine oxidoreductase 59 481 9.1E-52 T 13-09-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 THL1_RS17120 be928b8f4a7d9c04eb312e2630f6c3f5 495 PANTHER PTHR10742 38 490 2.7E-81 T 13-09-2016 THL1_RS17120 be928b8f4a7d9c04eb312e2630f6c3f5 495 PANTHER PTHR10742:SF216 38 490 2.7E-81 T 13-09-2016 THL1_RS17120 be928b8f4a7d9c04eb312e2630f6c3f5 495 SUPERFAMILY SSF54373 333 434 6.54E-22 T 13-09-2016 THL1_RS17120 be928b8f4a7d9c04eb312e2630f6c3f5 495 Gene3D G3DSA:3.90.660.10 266 435 7.7E-37 T 13-09-2016 THL1_RS17120 be928b8f4a7d9c04eb312e2630f6c3f5 495 PRINTS PR00757 Flavin-containing amine oxidase signature 51 70 3.2E-23 T 13-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 THL1_RS17120 be928b8f4a7d9c04eb312e2630f6c3f5 495 PRINTS PR00757 Flavin-containing amine oxidase signature 335 354 3.2E-23 T 13-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 THL1_RS17120 be928b8f4a7d9c04eb312e2630f6c3f5 495 PRINTS PR00757 Flavin-containing amine oxidase signature 466 483 3.2E-23 T 13-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 THL1_RS17120 be928b8f4a7d9c04eb312e2630f6c3f5 495 PRINTS PR00757 Flavin-containing amine oxidase signature 237 259 3.2E-23 T 13-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 THL1_RS17120 be928b8f4a7d9c04eb312e2630f6c3f5 495 PRINTS PR00757 Flavin-containing amine oxidase signature 435 457 3.2E-23 T 13-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 THL1_RS17120 be928b8f4a7d9c04eb312e2630f6c3f5 495 Gene3D G3DSA:3.50.50.60 36 98 3.1E-8 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 SUPERFAMILY SSF47384 238 268 9.81E-6 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 SUPERFAMILY SSF47384 161 210 9.81E-6 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 Gene3D G3DSA:1.10.287.130 237 257 3.4E-4 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 Gene3D G3DSA:1.10.287.130 171 201 3.4E-4 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 PANTHER PTHR24423:SF497 152 203 1.9E-91 T 13-09-2016 THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 PANTHER PTHR24423:SF497 234 419 1.9E-91 T 13-09-2016 THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 SUPERFAMILY SSF55785 12 83 4.01E-11 T 13-09-2016 IPR000014 PAS domain THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 Gene3D G3DSA:3.30.450.20 10 78 2.0E-9 T 13-09-2016 THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 Gene3D G3DSA:3.30.565.10 258 419 8.8E-45 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 417 1.2E-23 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 SUPERFAMILY SSF55874 260 418 2.13E-44 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 415 2.5E-20 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 361 2.5E-20 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 375 2.5E-20 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 396 2.5E-20 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 PANTHER PTHR24423:SF497 13 130 1.9E-91 T 13-09-2016 THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 PANTHER PTHR24423 234 419 1.9E-91 T 13-09-2016 THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 SMART SM00091 8 74 2.9E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 PANTHER PTHR24423 152 203 1.9E-91 T 13-09-2016 THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 Pfam PF00989 PAS fold 12 75 4.5E-7 T 13-09-2016 IPR013767 PAS fold GO:0006355 THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 PANTHER PTHR24423 13 130 1.9E-91 T 13-09-2016 THL1_RS02895 34977b1c7f4e09c10337f5d1d21f2f7c 429 SMART SM00387 310 418 2.7E-32 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS04110 52370fe5441a7b4c4daf6d00d570152b 633 SUPERFAMILY SSF46689 538 629 3.81E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS04110 52370fe5441a7b4c4daf6d00d570152b 633 Gene3D G3DSA:3.40.50.300 334 501 1.0E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04110 52370fe5441a7b4c4daf6d00d570152b 633 SUPERFAMILY SSF52540 338 568 8.27E-60 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04110 52370fe5441a7b4c4daf6d00d570152b 633 SUPERFAMILY SSF55781 67 206 6.38E-10 T 13-09-2016 IPR029016 GAF domain-like THL1_RS04110 52370fe5441a7b4c4daf6d00d570152b 633 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 353 366 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS04110 52370fe5441a7b4c4daf6d00d570152b 633 Gene3D G3DSA:1.10.10.60 572 629 3.1E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS04110 52370fe5441a7b4c4daf6d00d570152b 633 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 416 431 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS04110 52370fe5441a7b4c4daf6d00d570152b 633 Gene3D G3DSA:1.10.8.60 504 571 2.5E-16 T 13-09-2016 THL1_RS04110 52370fe5441a7b4c4daf6d00d570152b 633 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 610 630 1.7E-8 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS04110 52370fe5441a7b4c4daf6d00d570152b 633 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 593 610 1.7E-8 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS04110 52370fe5441a7b4c4daf6d00d570152b 633 SMART SM00382 349 492 6.1E-10 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS04110 52370fe5441a7b4c4daf6d00d570152b 633 PANTHER PTHR32071:SF5 292 629 2.3E-158 T 13-09-2016 THL1_RS04110 52370fe5441a7b4c4daf6d00d570152b 633 PANTHER PTHR32071 292 629 2.3E-158 T 13-09-2016 THL1_RS04110 52370fe5441a7b4c4daf6d00d570152b 633 Gene3D G3DSA:3.30.450.20 235 310 1.2E-6 T 13-09-2016 THL1_RS04110 52370fe5441a7b4c4daf6d00d570152b 633 Pfam PF00158 Sigma-54 interaction domain 333 493 1.7E-62 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS04110 52370fe5441a7b4c4daf6d00d570152b 633 SUPERFAMILY SSF55785 233 310 5.31E-9 T 13-09-2016 IPR000014 PAS domain THL1_RS04110 52370fe5441a7b4c4daf6d00d570152b 633 Pfam PF02954 Bacterial regulatory protein, Fis family 587 627 2.7E-14 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS01330 49e41d5585bd3c5276c9e0f92745d863 394 Gene3D G3DSA:3.40.640.10 12 257 1.3E-87 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS01330 49e41d5585bd3c5276c9e0f92745d863 394 PANTHER PTHR11808:SF15 1 394 3.5E-200 T 13-09-2016 THL1_RS01330 49e41d5585bd3c5276c9e0f92745d863 394 PIRSF PIRSF001434 1 394 9.5E-144 T 13-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 THL1_RS01330 49e41d5585bd3c5276c9e0f92745d863 394 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 14 391 6.5E-147 T 13-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 THL1_RS01330 49e41d5585bd3c5276c9e0f92745d863 394 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 197 211 - T 13-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 THL1_RS01330 49e41d5585bd3c5276c9e0f92745d863 394 SUPERFAMILY SSF53383 12 393 2.79E-118 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS01330 49e41d5585bd3c5276c9e0f92745d863 394 PANTHER PTHR11808 1 394 3.5E-200 T 13-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 THL1_RS01330 49e41d5585bd3c5276c9e0f92745d863 394 Gene3D G3DSA:3.90.1150.10 258 393 4.7E-56 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS12255 165cce50e76c64d5ef5c90c1ae7f2109 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 10 96 1.5E-23 T 13-09-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 THL1_RS12255 165cce50e76c64d5ef5c90c1ae7f2109 102 PANTHER PTHR11434 5 102 2.9E-61 T 13-09-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 THL1_RS12255 165cce50e76c64d5ef5c90c1ae7f2109 102 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 4 102 19.212 T 13-09-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 THL1_RS12255 165cce50e76c64d5ef5c90c1ae7f2109 102 PANTHER PTHR11434:SF4 5 102 2.9E-61 T 13-09-2016 THL1_RS18350 12e4a9fa7e834ecd6bad88200a148c52 291 Gene3D G3DSA:3.40.190.10 190 256 3.7E-7 T 13-09-2016 THL1_RS18350 12e4a9fa7e834ecd6bad88200a148c52 291 SUPERFAMILY SSF46785 6 89 6.65E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS18350 12e4a9fa7e834ecd6bad88200a148c52 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 9.8E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS18350 12e4a9fa7e834ecd6bad88200a148c52 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 9.8E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS18350 12e4a9fa7e834ecd6bad88200a148c52 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 9.8E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS18350 12e4a9fa7e834ecd6bad88200a148c52 291 PANTHER PTHR30126:SF29 3 290 1.2E-111 T 13-09-2016 THL1_RS18350 12e4a9fa7e834ecd6bad88200a148c52 291 PANTHER PTHR30126 3 290 1.2E-111 T 13-09-2016 THL1_RS18350 12e4a9fa7e834ecd6bad88200a148c52 291 Pfam PF03466 LysR substrate binding domain 89 290 5.9E-27 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS18350 12e4a9fa7e834ecd6bad88200a148c52 291 Gene3D G3DSA:3.40.190.10 81 189 2.3E-10 T 13-09-2016 THL1_RS18350 12e4a9fa7e834ecd6bad88200a148c52 291 SUPERFAMILY SSF53850 90 291 3.98E-28 T 13-09-2016 THL1_RS18350 12e4a9fa7e834ecd6bad88200a148c52 291 Gene3D G3DSA:1.10.10.10 3 80 5.3E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS18350 12e4a9fa7e834ecd6bad88200a148c52 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 6.3E-18 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19065 bfa8da236ee39d6c75a6e3aed24204bf 469 PIRSF PIRSF002744 1 467 1.3E-107 T 13-09-2016 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 THL1_RS19065 bfa8da236ee39d6c75a6e3aed24204bf 469 PANTHER PTHR31806 9 460 6.9E-103 T 13-09-2016 THL1_RS19065 bfa8da236ee39d6c75a6e3aed24204bf 469 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 19 440 2.1E-53 T 13-09-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 THL1_RS20240 223d4c0d60b9f7245e7836a148e51263 156 SUPERFAMILY SSF54637 5 141 2.09E-40 T 13-09-2016 IPR029069 HotDog domain THL1_RS20240 223d4c0d60b9f7245e7836a148e51263 156 Pfam PF01575 MaoC like domain 16 112 1.2E-23 T 13-09-2016 IPR002539 MaoC-like domain THL1_RS20240 223d4c0d60b9f7245e7836a148e51263 156 PRINTS PR01483 Fatty acid synthase signature 26 48 5.2E-5 T 13-09-2016 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 THL1_RS20240 223d4c0d60b9f7245e7836a148e51263 156 PRINTS PR01483 Fatty acid synthase signature 48 69 5.2E-5 T 13-09-2016 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 THL1_RS20240 223d4c0d60b9f7245e7836a148e51263 156 PANTHER PTHR13078 9 156 3.9E-41 T 13-09-2016 THL1_RS20240 223d4c0d60b9f7245e7836a148e51263 156 Gene3D G3DSA:3.10.129.10 9 139 3.6E-44 T 13-09-2016 IPR029069 HotDog domain THL1_RS02430 f3ba5e6d65d15a1b51f331c274c0cb8c 332 PANTHER PTHR30614:SF0 21 332 3.6E-126 T 13-09-2016 THL1_RS02430 f3ba5e6d65d15a1b51f331c274c0cb8c 332 SUPERFAMILY SSF161098 129 314 2.22E-46 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS02430 f3ba5e6d65d15a1b51f331c274c0cb8c 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 148 329 7.0E-26 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS02430 f3ba5e6d65d15a1b51f331c274c0cb8c 332 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 129 223 5.2E-27 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS02430 f3ba5e6d65d15a1b51f331c274c0cb8c 332 Gene3D G3DSA:1.10.3720.10 127 329 5.5E-52 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS02430 f3ba5e6d65d15a1b51f331c274c0cb8c 332 PANTHER PTHR30614 21 332 3.6E-126 T 13-09-2016 THL1_RS28350 85a9efe34b9df6076978b88d338db984 446 Gene3D G3DSA:1.10.8.60 317 369 5.8E-22 T 13-09-2016 THL1_RS28350 85a9efe34b9df6076978b88d338db984 446 SMART SM00448 3 114 2.1E-30 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS28350 85a9efe34b9df6076978b88d338db984 446 SMART SM00382 164 307 9.6E-11 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS28350 85a9efe34b9df6076978b88d338db984 446 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 230 245 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS28350 85a9efe34b9df6076978b88d338db984 446 Gene3D G3DSA:3.40.50.300 143 316 5.6E-54 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28350 85a9efe34b9df6076978b88d338db984 446 Gene3D G3DSA:1.10.10.60 370 435 5.4E-7 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS28350 85a9efe34b9df6076978b88d338db984 446 SUPERFAMILY SSF52540 144 373 5.63E-68 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28350 85a9efe34b9df6076978b88d338db984 446 PANTHER PTHR32071 1 446 1.5E-243 T 13-09-2016 THL1_RS28350 85a9efe34b9df6076978b88d338db984 446 Pfam PF00158 Sigma-54 interaction domain 145 310 3.4E-67 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS28350 85a9efe34b9df6076978b88d338db984 446 PANTHER PTHR32071:SF40 1 446 1.5E-243 T 13-09-2016 THL1_RS28350 85a9efe34b9df6076978b88d338db984 446 SUPERFAMILY SSF46689 357 435 5.82E-7 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS28350 85a9efe34b9df6076978b88d338db984 446 SUPERFAMILY SSF52172 4 187 7.68E-43 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS28350 85a9efe34b9df6076978b88d338db984 446 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 168 181 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS28350 85a9efe34b9df6076978b88d338db984 446 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 357 366 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS28350 85a9efe34b9df6076978b88d338db984 446 Gene3D G3DSA:3.40.50.2300 3 127 1.4E-37 T 13-09-2016 THL1_RS28350 85a9efe34b9df6076978b88d338db984 446 Pfam PF02954 Bacterial regulatory protein, Fis family 396 433 3.9E-5 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS28350 85a9efe34b9df6076978b88d338db984 446 Pfam PF00072 Response regulator receiver domain 5 114 1.0E-26 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS25270 8e69b2b237afed668a1cb4b93c4054dc 309 SUPERFAMILY SSF144020 20 307 1.44E-80 T 13-09-2016 IPR024064 FdhE-like THL1_RS25270 8e69b2b237afed668a1cb4b93c4054dc 309 Pfam PF04216 Protein involved in formate dehydrogenase formation 16 304 8.5E-94 T 13-09-2016 IPR006452 Formate dehydrogenase accessory protein GO:0005737 THL1_RS25270 8e69b2b237afed668a1cb4b93c4054dc 309 Gene3D G3DSA:3.90.1670.10 24 307 5.1E-83 T 13-09-2016 IPR024064 FdhE-like THL1_RS25270 8e69b2b237afed668a1cb4b93c4054dc 309 PANTHER PTHR37689 1 309 3.5E-85 T 13-09-2016 THL1_RS25270 8e69b2b237afed668a1cb4b93c4054dc 309 PIRSF PIRSF018296 2 309 1.3E-99 T 13-09-2016 IPR006452 Formate dehydrogenase accessory protein GO:0005737 THL1_RS25270 8e69b2b237afed668a1cb4b93c4054dc 309 Hamap MF_00611 Protein FdhE [fdhE]. 3 307 37.051 T 13-09-2016 IPR006452 Formate dehydrogenase accessory protein GO:0005737 THL1_RS25270 8e69b2b237afed668a1cb4b93c4054dc 309 TIGRFAM TIGR01562 FdhE: formate dehydrogenase accessory protein FdhE 5 306 2.3E-113 T 13-09-2016 IPR006452 Formate dehydrogenase accessory protein GO:0005737 THL1_RS25270 8e69b2b237afed668a1cb4b93c4054dc 309 PANTHER PTHR37689:SF1 1 309 3.5E-85 T 13-09-2016 THL1_RS18795 541248624442606598271151255e1365 436 Gene3D G3DSA:1.20.5.100 203 234 1.0E-13 T 13-09-2016 THL1_RS18795 541248624442606598271151255e1365 436 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 205 298 2.9E-29 T 13-09-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 THL1_RS18795 541248624442606598271151255e1365 436 SUPERFAMILY SSF52413 305 424 1.44E-25 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS18795 541248624442606598271151255e1365 436 Gene3D G3DSA:3.40.50.720 235 425 3.0E-43 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18795 541248624442606598271151255e1365 436 PIRSF PIRSF000124 1 436 2.0E-138 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS18795 541248624442606598271151255e1365 436 Gene3D G3DSA:3.40.50.720 1 194 7.9E-67 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18795 541248624442606598271151255e1365 436 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 318 423 6.5E-15 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS18795 541248624442606598271151255e1365 436 SMART SM00984 317 425 2.3E-22 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS18795 541248624442606598271151255e1365 436 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 419 2.4E-129 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS18795 541248624442606598271151255e1365 436 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 189 8.2E-61 T 13-09-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS18795 541248624442606598271151255e1365 436 SUPERFAMILY SSF51735 1 195 4.17E-49 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18795 541248624442606598271151255e1365 436 PANTHER PTHR11374:SF22 1 396 2.2E-232 T 13-09-2016 THL1_RS18795 541248624442606598271151255e1365 436 SUPERFAMILY SSF48179 204 300 3.17E-28 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS18795 541248624442606598271151255e1365 436 PANTHER PTHR11374 1 396 2.2E-232 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS18795 541248624442606598271151255e1365 436 PIRSF PIRSF500135 1 436 1.8E-231 T 13-09-2016 IPR028358 GDP-mannose 6-dehydrogenase GO:0042121|GO:0047919 KEGG: 00040+1.1.1.13|KEGG: 00051+1.1.1.132|KEGG: 00520+1.1.1.132|MetaCyc: PWY-6073|MetaCyc: PWY-6082|UniPathway: UPA00286 THL1_RS04955 9845e5fbc689e1f662ef9d0139011e85 533 Gene3D G3DSA:3.30.565.10 364 526 2.1E-30 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS04955 9845e5fbc689e1f662ef9d0139011e85 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 490 508 4.0E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS04955 9845e5fbc689e1f662ef9d0139011e85 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 475 4.0E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS04955 9845e5fbc689e1f662ef9d0139011e85 533 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 489 4.0E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS04955 9845e5fbc689e1f662ef9d0139011e85 533 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 420 526 8.3E-17 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS04955 9845e5fbc689e1f662ef9d0139011e85 533 SUPERFAMILY SSF55785 189 245 3.35E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS04955 9845e5fbc689e1f662ef9d0139011e85 533 PANTHER PTHR24423 197 526 1.4E-139 T 13-09-2016 THL1_RS04955 9845e5fbc689e1f662ef9d0139011e85 533 Gene3D G3DSA:1.10.287.130 306 363 4.1E-13 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS04955 9845e5fbc689e1f662ef9d0139011e85 533 PANTHER PTHR24423:SF483 197 526 1.4E-139 T 13-09-2016 THL1_RS04955 9845e5fbc689e1f662ef9d0139011e85 533 Pfam PF00512 His Kinase A (phospho-acceptor) domain 312 376 2.1E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS04955 9845e5fbc689e1f662ef9d0139011e85 533 SMART SM00387 419 530 4.4E-30 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS04955 9845e5fbc689e1f662ef9d0139011e85 533 SUPERFAMILY SSF55874 368 526 1.44E-31 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS04955 9845e5fbc689e1f662ef9d0139011e85 533 SUPERFAMILY SSF47384 301 376 4.32E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS04955 9845e5fbc689e1f662ef9d0139011e85 533 SMART SM00388 312 378 4.0E-17 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS04955 9845e5fbc689e1f662ef9d0139011e85 533 Gene3D G3DSA:3.30.450.20 198 266 5.3E-7 T 13-09-2016 THL1_RS09860 19d2fd530ce0a41fd40d5f45155913c1 391 Gene3D G3DSA:3.40.640.10 9 256 4.4E-77 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS09860 19d2fd530ce0a41fd40d5f45155913c1 391 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 13 381 2.3E-96 T 13-09-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THL1_RS09860 19d2fd530ce0a41fd40d5f45155913c1 391 PANTHER PTHR30244 10 389 5.1E-84 T 13-09-2016 THL1_RS09860 19d2fd530ce0a41fd40d5f45155913c1 391 Gene3D G3DSA:3.90.1150.10 258 382 2.2E-14 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS09860 19d2fd530ce0a41fd40d5f45155913c1 391 SUPERFAMILY SSF53383 8 386 7.8E-104 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS09860 19d2fd530ce0a41fd40d5f45155913c1 391 PANTHER PTHR30244:SF16 10 389 5.1E-84 T 13-09-2016 THL1_RS09860 19d2fd530ce0a41fd40d5f45155913c1 391 PIRSF PIRSF000390 3 390 6.9E-116 T 13-09-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 Pfam PF00175 Oxidoreductase NAD-binding domain 1230 1336 1.6E-20 T 13-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 SUPERFAMILY SSF52343 1217 1372 2.36E-51 T 13-09-2016 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 SUPERFAMILY SSF52218 834 977 5.99E-41 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 Gene3D G3DSA:1.20.990.10 1052 1157 1.8E-30 T 13-09-2016 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3 GO:0016491|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 Gene3D G3DSA:3.40.228.10 136 315 5.4E-66 T 13-09-2016 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 Pfam PF00384 Molybdopterin oxidoreductase 81 487 2.3E-72 T 13-09-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1041 1051 9.7E-27 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1321 1329 9.7E-27 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1254 1263 9.7E-27 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1267 1278 9.7E-27 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1298 1314 9.7E-27 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1160 1167 9.7E-27 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1229 1248 9.7E-27 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 1193 1202 9.7E-27 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 54 4.6E-20 T 13-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 Pfam PF01568 Molydopterin dinucleotide binding domain 600 709 9.0E-34 T 13-09-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 Gene3D G3DSA:2.20.25.90 3 54 4.2E-21 T 13-09-2016 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 SUPERFAMILY SSF63380 1000 1219 6.54E-60 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 Pfam PF00258 Flavodoxin 838 969 2.6E-26 T 13-09-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 SUPERFAMILY SSF53706 3 515 1.96E-182 T 13-09-2016 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 Gene3D G3DSA:2.40.40.20 532 717 8.8E-55 T 13-09-2016 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 SUPERFAMILY SSF50692 573 714 6.56E-44 T 13-09-2016 IPR009010 Aspartate decarboxylase-like domain THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 Pfam PF00667 FAD binding domain 1003 1198 1.0E-32 T 13-09-2016 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 PRINTS PR00369 Flavodoxin signature 941 960 7.0E-11 T 13-09-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 PRINTS PR00369 Flavodoxin signature 917 927 7.0E-11 T 13-09-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 PRINTS PR00369 Flavodoxin signature 885 896 7.0E-11 T 13-09-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 PRINTS PR00369 Flavodoxin signature 837 850 7.0E-11 T 13-09-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 Gene3D G3DSA:3.40.50.740 61 134 2.1E-62 T 13-09-2016 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 Gene3D G3DSA:3.40.50.740 316 338 2.1E-62 T 13-09-2016 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 Gene3D G3DSA:3.40.50.740 374 520 2.1E-62 T 13-09-2016 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 Gene3D G3DSA:2.40.30.10 1158 1227 7.3E-38 T 13-09-2016 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 Gene3D G3DSA:2.40.30.10 1000 1051 7.3E-38 T 13-09-2016 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 Gene3D G3DSA:3.40.50.360 830 977 4.2E-41 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 Gene3D G3DSA:3.40.50.80 1228 1371 1.4E-59 T 13-09-2016 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 PANTHER PTHR19384 834 1372 4.1E-191 T 13-09-2016 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 SMART SM00926 3 57 9.5E-20 T 13-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 THL1_RS19915 3bf348ef2d9197e92d5d812bcd6326bd 1372 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 8 26 - T 13-09-2016 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 THL1_RS13820 8016f4f3a73df42b3d96489811fe6f29 389 Gene3D G3DSA:1.20.140.10 198 388 5.9E-43 T 13-09-2016 THL1_RS13820 8016f4f3a73df42b3d96489811fe6f29 389 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 236 367 3.3E-39 T 13-09-2016 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain THL1_RS13820 8016f4f3a73df42b3d96489811fe6f29 389 SUPERFAMILY SSF47203 233 381 8.86E-17 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS13820 8016f4f3a73df42b3d96489811fe6f29 389 Gene3D G3DSA:2.40.110.10 112 197 3.1E-24 T 13-09-2016 THL1_RS13820 8016f4f3a73df42b3d96489811fe6f29 389 SUPERFAMILY SSF56645 15 199 4.06E-30 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS13820 8016f4f3a73df42b3d96489811fe6f29 389 PANTHER PTHR10909:SF316 18 380 4.8E-36 T 13-09-2016 THL1_RS13820 8016f4f3a73df42b3d96489811fe6f29 389 PANTHER PTHR10909 18 380 4.8E-36 T 13-09-2016 THL1_RS13820 8016f4f3a73df42b3d96489811fe6f29 389 PIRSF PIRSF016578 1 389 2.1E-129 T 13-09-2016 THL1_RS13820 8016f4f3a73df42b3d96489811fe6f29 389 Gene3D G3DSA:1.10.540.10 4 109 1.2E-35 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS23930 90e7aafc5eb0f8f37024fc73bcaeb1a6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.3E-17 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23930 90e7aafc5eb0f8f37024fc73bcaeb1a6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.3E-17 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23930 90e7aafc5eb0f8f37024fc73bcaeb1a6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.3E-17 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23930 90e7aafc5eb0f8f37024fc73bcaeb1a6 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.3E-17 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23930 90e7aafc5eb0f8f37024fc73bcaeb1a6 257 Gene3D G3DSA:3.40.50.720 5 212 2.0E-49 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23930 90e7aafc5eb0f8f37024fc73bcaeb1a6 257 PANTHER PTHR24322:SF57 9 134 1.2E-36 T 13-09-2016 THL1_RS23930 90e7aafc5eb0f8f37024fc73bcaeb1a6 257 PANTHER PTHR24322:SF57 150 182 1.2E-36 T 13-09-2016 THL1_RS23930 90e7aafc5eb0f8f37024fc73bcaeb1a6 257 PANTHER PTHR24322 9 134 1.2E-36 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23930 90e7aafc5eb0f8f37024fc73bcaeb1a6 257 SUPERFAMILY SSF51735 5 246 1.57E-52 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23930 90e7aafc5eb0f8f37024fc73bcaeb1a6 257 Pfam PF00106 short chain dehydrogenase 7 190 6.1E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23930 90e7aafc5eb0f8f37024fc73bcaeb1a6 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS23930 90e7aafc5eb0f8f37024fc73bcaeb1a6 257 PANTHER PTHR24322 150 182 1.2E-36 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS02210 3d798d5465277c7f6108ef36107b363a 592 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 468 585 1.5E-34 T 13-09-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain THL1_RS02210 3d798d5465277c7f6108ef36107b363a 592 Gene3D G3DSA:2.40.110.10 162 268 1.4E-27 T 13-09-2016 THL1_RS02210 3d798d5465277c7f6108ef36107b363a 592 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 2.2E-12 T 13-09-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria THL1_RS02210 3d798d5465277c7f6108ef36107b363a 592 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 42 158 7.0E-10 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS02210 3d798d5465277c7f6108ef36107b363a 592 SUPERFAMILY SSF56645 39 275 7.33E-54 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS02210 3d798d5465277c7f6108ef36107b363a 592 SUPERFAMILY SSF47203 289 473 2.74E-45 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS02210 3d798d5465277c7f6108ef36107b363a 592 Gene3D G3DSA:1.10.540.10 39 160 3.2E-13 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS02210 3d798d5465277c7f6108ef36107b363a 592 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 163 272 1.1E-17 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS02210 3d798d5465277c7f6108ef36107b363a 592 PANTHER PTHR10909 1 477 9.2E-268 T 13-09-2016 THL1_RS02210 3d798d5465277c7f6108ef36107b363a 592 PANTHER PTHR10909:SF296 1 477 9.2E-268 T 13-09-2016 THL1_RS02210 3d798d5465277c7f6108ef36107b363a 592 Gene3D G3DSA:1.20.140.10 269 460 1.9E-48 T 13-09-2016 THL1_RS02210 3d798d5465277c7f6108ef36107b363a 592 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 283 452 1.9E-19 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS11755 93491d0c37c9fa677845ba197af7e790 165 Gene3D G3DSA:3.10.50.30 85 164 4.6E-30 T 13-09-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 THL1_RS11755 93491d0c37c9fa677845ba197af7e790 165 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 12 165 2.6E-78 T 13-09-2016 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 THL1_RS11755 93491d0c37c9fa677845ba197af7e790 165 PANTHER PTHR30437 1 165 2.1E-91 T 13-09-2016 THL1_RS11755 93491d0c37c9fa677845ba197af7e790 165 PIRSF PIRSF006092 10 165 1.2E-48 T 13-09-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 THL1_RS11755 93491d0c37c9fa677845ba197af7e790 165 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 92 164 1.9E-25 T 13-09-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 THL1_RS11755 93491d0c37c9fa677845ba197af7e790 165 SUPERFAMILY SSF54534 89 164 6.28E-23 T 13-09-2016 THL1_RS11755 93491d0c37c9fa677845ba197af7e790 165 SUPERFAMILY SSF46557 13 85 2.09E-24 T 13-09-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 THL1_RS11755 93491d0c37c9fa677845ba197af7e790 165 Hamap MF_00105 Transcription elongation factor GreA [greA]. 11 163 28.532 T 13-09-2016 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 THL1_RS11755 93491d0c37c9fa677845ba197af7e790 165 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 26 57 - T 13-09-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 THL1_RS11755 93491d0c37c9fa677845ba197af7e790 165 PANTHER PTHR30437:SF6 1 165 2.1E-91 T 13-09-2016 THL1_RS11755 93491d0c37c9fa677845ba197af7e790 165 Gene3D G3DSA:1.10.287.180 14 84 6.3E-25 T 13-09-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 THL1_RS11755 93491d0c37c9fa677845ba197af7e790 165 Hamap MF_00930 Transcription elongation factor GreB [greB]. 10 165 52.548 T 13-09-2016 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 THL1_RS11755 93491d0c37c9fa677845ba197af7e790 165 Pfam PF03449 Transcription elongation factor, N-terminal 14 83 4.9E-25 T 13-09-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 PANTHER PTHR19376 1177 1262 0.0 T 13-09-2016 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 Gene3D G3DSA:2.40.50.100 1156 1211 2.8E-6 T 13-09-2016 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 382 1.7E-7 T 13-09-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 Pfam PF00623 RNA polymerase Rpb1, domain 2 388 485 1.8E-28 T 13-09-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 Pfam PF04997 RNA polymerase Rpb1, domain 1 16 342 8.0E-91 T 13-09-2016 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 15 1376 10.554 T 13-09-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 Gene3D G3DSA:2.40.40.20 417 489 3.2E-37 T 13-09-2016 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 Gene3D G3DSA:2.40.40.20 349 376 3.2E-37 T 13-09-2016 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 Pfam PF04998 RNA polymerase Rpb1, domain 5 766 1316 9.7E-78 T 13-09-2016 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 SUPERFAMILY SSF64484 1133 1363 0.0 T 13-09-2016 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 SUPERFAMILY SSF64484 16 944 0.0 T 13-09-2016 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 SMART SM00663 235 514 2.2E-185 T 13-09-2016 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 PANTHER PTHR19376 1303 1398 0.0 T 13-09-2016 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 PANTHER PTHR19376:SF32 1303 1398 0.0 T 13-09-2016 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 PANTHER PTHR19376:SF32 1177 1262 0.0 T 13-09-2016 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 PANTHER PTHR19376:SF32 570 943 0.0 T 13-09-2016 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 Pfam PF05000 RNA polymerase Rpb1, domain 4 674 763 4.5E-20 T 13-09-2016 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1366 0.0 T 13-09-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 643 2.9E-29 T 13-09-2016 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 PANTHER PTHR19376:SF32 963 1157 0.0 T 13-09-2016 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 PANTHER PTHR19376 4 551 0.0 T 13-09-2016 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 PANTHER PTHR19376:SF32 4 551 0.0 T 13-09-2016 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 PANTHER PTHR19376 963 1157 0.0 T 13-09-2016 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 PANTHER PTHR19376 570 943 0.0 T 13-09-2016 THL1_RS03495 22c7d8394b4d43de3ef1f1565aaf2857 1399 Hamap MF_01323 DNA-directed RNA polymerase subunit gamma [rpoC1]. 13 588 32.143 T 13-09-2016 THL1_RS24885 2575dc3e668b82b7b81662dca73b37c5 278 Pfam PF00797 N-acetyltransferase 25 263 4.4E-60 T 13-09-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 THL1_RS24885 2575dc3e668b82b7b81662dca73b37c5 278 PRINTS PR01543 Arylamine N-acetyltransferase signature 25 48 1.5E-12 T 13-09-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 THL1_RS24885 2575dc3e668b82b7b81662dca73b37c5 278 PRINTS PR01543 Arylamine N-acetyltransferase signature 49 72 1.5E-12 T 13-09-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 THL1_RS24885 2575dc3e668b82b7b81662dca73b37c5 278 PRINTS PR01543 Arylamine N-acetyltransferase signature 73 95 1.5E-12 T 13-09-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 THL1_RS24885 2575dc3e668b82b7b81662dca73b37c5 278 PRINTS PR01543 Arylamine N-acetyltransferase signature 107 132 1.5E-12 T 13-09-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 THL1_RS24885 2575dc3e668b82b7b81662dca73b37c5 278 PANTHER PTHR11786:SF0 1 264 9.1E-53 T 13-09-2016 THL1_RS24885 2575dc3e668b82b7b81662dca73b37c5 278 SUPERFAMILY SSF54001 2 271 3.92E-72 T 13-09-2016 THL1_RS24885 2575dc3e668b82b7b81662dca73b37c5 278 PANTHER PTHR11786 1 264 9.1E-53 T 13-09-2016 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: REACT_13433 THL1_RS24885 2575dc3e668b82b7b81662dca73b37c5 278 Gene3D G3DSA:3.30.2140.10 189 273 5.6E-47 T 13-09-2016 THL1_RS24885 2575dc3e668b82b7b81662dca73b37c5 278 Gene3D G3DSA:3.30.2140.10 5 89 5.6E-47 T 13-09-2016 THL1_RS17720 5275a0fdc90fe4e2cac98bb4331e926a 219 Gene3D G3DSA:3.90.70.10 53 171 0.001 T 13-09-2016 THL1_RS05260 5ba48c6c1a5b5fe5be3a6e87f157f411 186 Gene3D G3DSA:1.10.10.60 132 185 6.1E-30 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS05260 5ba48c6c1a5b5fe5be3a6e87f157f411 186 SMART SM00448 13 124 1.8E-19 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS05260 5ba48c6c1a5b5fe5be3a6e87f157f411 186 PANTHER PTHR26402 13 124 3.3E-59 T 13-09-2016 THL1_RS05260 5ba48c6c1a5b5fe5be3a6e87f157f411 186 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 148 165 2.6E-7 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS05260 5ba48c6c1a5b5fe5be3a6e87f157f411 186 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 165 185 2.6E-7 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS05260 5ba48c6c1a5b5fe5be3a6e87f157f411 186 Pfam PF00072 Response regulator receiver domain 16 124 8.8E-20 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS05260 5ba48c6c1a5b5fe5be3a6e87f157f411 186 Pfam PF02954 Bacterial regulatory protein, Fis family 148 181 7.8E-12 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS05260 5ba48c6c1a5b5fe5be3a6e87f157f411 186 SUPERFAMILY SSF52172 12 171 6.55E-30 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS05260 5ba48c6c1a5b5fe5be3a6e87f157f411 186 PANTHER PTHR26402:SF344 13 124 3.3E-59 T 13-09-2016 THL1_RS05260 5ba48c6c1a5b5fe5be3a6e87f157f411 186 Gene3D G3DSA:3.40.50.2300 14 125 1.4E-27 T 13-09-2016 THL1_RS15600 50059b7d044eceec7e3163465f93ea8a 397 PANTHER PTHR18919 3 397 2.6E-227 T 13-09-2016 THL1_RS15600 50059b7d044eceec7e3163465f93ea8a 397 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 394 4.6E-126 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS15600 50059b7d044eceec7e3163465f93ea8a 397 Pfam PF02803 Thiolase, C-terminal domain 273 394 2.9E-41 T 13-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THL1_RS15600 50059b7d044eceec7e3163465f93ea8a 397 Gene3D G3DSA:3.40.47.10 146 198 1.3E-54 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15600 50059b7d044eceec7e3163465f93ea8a 397 Gene3D G3DSA:3.40.47.10 280 394 1.3E-54 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15600 50059b7d044eceec7e3163465f93ea8a 397 Pfam PF00108 Thiolase, N-terminal domain 8 264 8.9E-87 T 13-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THL1_RS15600 50059b7d044eceec7e3163465f93ea8a 397 PANTHER PTHR18919:SF110 3 397 2.6E-227 T 13-09-2016 THL1_RS15600 50059b7d044eceec7e3163465f93ea8a 397 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 88 106 - T 13-09-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 THL1_RS15600 50059b7d044eceec7e3163465f93ea8a 397 SUPERFAMILY SSF53901 8 273 1.58E-77 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15600 50059b7d044eceec7e3163465f93ea8a 397 PIRSF PIRSF000429 2 397 4.3E-113 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS15600 50059b7d044eceec7e3163465f93ea8a 397 Gene3D G3DSA:3.40.47.10 8 127 5.9E-70 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15600 50059b7d044eceec7e3163465f93ea8a 397 Gene3D G3DSA:3.40.47.10 199 279 5.9E-70 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15600 50059b7d044eceec7e3163465f93ea8a 397 SUPERFAMILY SSF53901 274 395 3.96E-39 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15600 50059b7d044eceec7e3163465f93ea8a 397 ProSitePatterns PS00099 Thiolases active site. 377 390 - T 13-09-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 THL1_RS20265 466d72c869b1a09b1a3b298907930b41 320 PANTHER PTHR32347 25 313 2.7E-39 T 13-09-2016 THL1_RS20265 466d72c869b1a09b1a3b298907930b41 320 Pfam PF13533 Biotin-lipoyl like 43 80 4.4E-8 T 13-09-2016 THL1_RS20265 466d72c869b1a09b1a3b298907930b41 320 PANTHER PTHR32347:SF12 25 313 2.7E-39 T 13-09-2016 THL1_RS20265 466d72c869b1a09b1a3b298907930b41 320 SUPERFAMILY SSF111369 33 90 2.75E-6 T 13-09-2016 THL1_RS20265 466d72c869b1a09b1a3b298907930b41 320 Gene3D G3DSA:2.40.50.100 193 223 3.8E-8 T 13-09-2016 THL1_RS20265 466d72c869b1a09b1a3b298907930b41 320 Gene3D G3DSA:2.40.50.100 43 66 3.8E-8 T 13-09-2016 THL1_RS20265 466d72c869b1a09b1a3b298907930b41 320 Pfam PF13437 HlyD family secretion protein 196 272 3.3E-6 T 13-09-2016 THL1_RS07040 fdbe2138cc2d2312a6771d57c24e2e3f 297 Gene3D G3DSA:3.10.180.10 133 293 2.0E-52 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS07040 fdbe2138cc2d2312a6771d57c24e2e3f 297 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 243 264 - T 13-09-2016 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 THL1_RS07040 fdbe2138cc2d2312a6771d57c24e2e3f 297 Gene3D G3DSA:3.10.180.10 3 131 1.2E-33 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS07040 fdbe2138cc2d2312a6771d57c24e2e3f 297 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 142 265 4.5E-21 T 13-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain THL1_RS07040 fdbe2138cc2d2312a6771d57c24e2e3f 297 SUPERFAMILY SSF54593 1 273 8.37E-36 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS17255 1dcdac808c61454c32f29a7240be2604 356 Pfam PF01636 Phosphotransferase enzyme family 38 273 7.5E-45 T 13-09-2016 IPR002575 Aminoglycoside phosphotransferase THL1_RS17255 1dcdac808c61454c32f29a7240be2604 356 Gene3D G3DSA:3.90.1200.10 133 341 4.1E-35 T 13-09-2016 THL1_RS17255 1dcdac808c61454c32f29a7240be2604 356 PANTHER PTHR21310:SF14 15 265 1.1E-15 T 13-09-2016 THL1_RS17255 1dcdac808c61454c32f29a7240be2604 356 SUPERFAMILY SSF56112 19 337 1.02E-57 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS17255 1dcdac808c61454c32f29a7240be2604 356 PANTHER PTHR21310 15 265 1.1E-15 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 Gene3D G3DSA:2.70.150.10 208 378 1.3E-29 T 13-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 186 789 4.4E-175 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 Gene3D G3DSA:3.40.50.1000 451 496 3.7E-51 T 13-09-2016 IPR023214 HAD-like domain THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 Gene3D G3DSA:3.40.50.1000 607 747 3.7E-51 T 13-09-2016 IPR023214 HAD-like domain THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 205 788 2.0E-179 T 13-09-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 SUPERFAMILY SSF81665 245 281 1.23E-12 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 SUPERFAMILY SSF81665 379 504 1.23E-12 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 482 488 - T 13-09-2016 IPR018303 P-type ATPase, phosphorylation site THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 Gene3D G3DSA:1.10.620.20 37 69 5.4E-4 T 13-09-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: REACT_1698 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 SMART SM00746 25 62 9.9E-10 T 13-09-2016 IPR011017 TRASH domain THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 SUPERFAMILY SSF56784 537 786 1.1E-54 T 13-09-2016 IPR023214 HAD-like domain THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 SUPERFAMILY SSF56784 478 498 1.1E-54 T 13-09-2016 IPR023214 HAD-like domain THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 249 758 4.6E-83 T 13-09-2016 IPR001757 P-type ATPase GO:0016021 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 PRINTS PR00943 Copper-transporting ATPase signature 656 673 2.1E-13 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 PRINTS PR00943 Copper-transporting ATPase signature 463 478 2.1E-13 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 PRINTS PR00943 Copper-transporting ATPase signature 190 209 2.1E-13 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 PRINTS PR00943 Copper-transporting ATPase signature 267 285 2.1E-13 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 PRINTS PR00943 Copper-transporting ATPase signature 401 415 2.1E-13 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 PRINTS PR00943 Copper-transporting ATPase signature 247 266 2.1E-13 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 Pfam PF04945 YHS domain 25 68 1.1E-16 T 13-09-2016 IPR007029 YHS domain THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 SUPERFAMILY SSF81653 281 378 4.18E-26 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 Pfam PF00122 E1-E2 ATPase 248 471 2.0E-64 T 13-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 480 494 5.1E-27 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 328 342 5.1E-27 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 626 636 5.1E-27 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 604 615 5.1E-27 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 702 714 5.1E-27 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 679 698 5.1E-27 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 PANTHER PTHR24093 124 790 1.7E-216 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 Pfam PF00702 haloacid dehalogenase-like hydrolase 476 693 1.9E-38 T 13-09-2016 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 Gene3D G3DSA:3.40.1110.10 497 606 1.9E-16 T 13-09-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 SUPERFAMILY SSF47240 24 67 1.87E-7 T 13-09-2016 IPR009078 Ferritin-like superfamily THL1_RS12830 799c0cfc66027e384574f022ef0c52c1 794 PANTHER PTHR24093:SF50 124 790 1.7E-216 T 13-09-2016 THL1_RS21930 2c7717729ef69b9ae3a30dd4ea95c719 1026 Pfam PF01336 OB-fold nucleic acid binding domain 936 1010 5.3E-9 T 13-09-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 THL1_RS21930 2c7717729ef69b9ae3a30dd4ea95c719 1026 Pfam PF02811 PHP domain 6 122 5.8E-17 T 13-09-2016 IPR004013 PHP domain GO:0003824 THL1_RS21930 2c7717729ef69b9ae3a30dd4ea95c719 1026 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 269 692 1.2E-144 T 13-09-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS21930 2c7717729ef69b9ae3a30dd4ea95c719 1026 SMART SM00481 5 72 1.5E-7 T 13-09-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 THL1_RS21930 2c7717729ef69b9ae3a30dd4ea95c719 1026 PANTHER PTHR32294:SF4 1 1015 0.0 T 13-09-2016 THL1_RS21930 2c7717729ef69b9ae3a30dd4ea95c719 1026 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 971 1.5E-165 T 13-09-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS21930 2c7717729ef69b9ae3a30dd4ea95c719 1026 Gene3D G3DSA:2.40.50.140 925 995 4.6E-4 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS21930 2c7717729ef69b9ae3a30dd4ea95c719 1026 Pfam PF14579 Helix-hairpin-helix motif 766 856 6.0E-23 T 13-09-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS21930 2c7717729ef69b9ae3a30dd4ea95c719 1026 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 4 1026 13.724 T 13-09-2016 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS21930 2c7717729ef69b9ae3a30dd4ea95c719 1026 Gene3D G3DSA:3.20.20.140 5 188 6.4E-10 T 13-09-2016 THL1_RS21930 2c7717729ef69b9ae3a30dd4ea95c719 1026 PANTHER PTHR32294 1 1015 0.0 T 13-09-2016 THL1_RS21930 2c7717729ef69b9ae3a30dd4ea95c719 1026 SUPERFAMILY SSF89550 4 81 5.49E-11 T 13-09-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 THL1_RS21930 2c7717729ef69b9ae3a30dd4ea95c719 1026 SUPERFAMILY SSF89550 108 186 5.49E-11 T 13-09-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 THL1_RS27665 d0b5c6e73fd73679d6d2aacbf6197942 87 SUPERFAMILY SSF143120 1 70 6.41E-12 T 13-09-2016 THL1_RS27665 d0b5c6e73fd73679d6d2aacbf6197942 87 PANTHER PTHR33713 1 86 5.4E-24 T 13-09-2016 THL1_RS27665 d0b5c6e73fd73679d6d2aacbf6197942 87 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 64 2.8E-8 T 13-09-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THL1_RS27665 d0b5c6e73fd73679d6d2aacbf6197942 87 PANTHER PTHR33713:SF2 1 86 5.4E-24 T 13-09-2016 THL1_RS27665 d0b5c6e73fd73679d6d2aacbf6197942 87 Gene3D G3DSA:3.40.1620.10 19 45 2.3E-4 T 13-09-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THL1_RS27665 d0b5c6e73fd73679d6d2aacbf6197942 87 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 19 49 1.2E-5 T 13-09-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THL1_RS26185 2a61256285eed7374624c0d1e489b1b9 977 SUPERFAMILY SSF81593 835 974 5.65E-28 T 13-09-2016 THL1_RS26185 2a61256285eed7374624c0d1e489b1b9 977 SUPERFAMILY SSF81301 544 831 2.62E-82 T 13-09-2016 THL1_RS26185 2a61256285eed7374624c0d1e489b1b9 977 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 571 825 1.1E-90 T 13-09-2016 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 THL1_RS26185 2a61256285eed7374624c0d1e489b1b9 977 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 46 293 1.1E-94 T 13-09-2016 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 THL1_RS26185 2a61256285eed7374624c0d1e489b1b9 977 Pfam PF08335 GlnD PII-uridylyltransferase 872 945 2.2E-11 T 13-09-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 THL1_RS26185 2a61256285eed7374624c0d1e489b1b9 977 Pfam PF08335 GlnD PII-uridylyltransferase 313 452 4.8E-43 T 13-09-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 THL1_RS26185 2a61256285eed7374624c0d1e489b1b9 977 PANTHER PTHR30621 38 977 0.0 T 13-09-2016 THL1_RS26185 2a61256285eed7374624c0d1e489b1b9 977 Gene3D G3DSA:3.30.460.10 658 828 4.3E-58 T 13-09-2016 THL1_RS26185 2a61256285eed7374624c0d1e489b1b9 977 Gene3D G3DSA:3.30.460.10 128 301 5.0E-64 T 13-09-2016 THL1_RS26185 2a61256285eed7374624c0d1e489b1b9 977 SUPERFAMILY SSF81593 303 452 5.73E-43 T 13-09-2016 THL1_RS26185 2a61256285eed7374624c0d1e489b1b9 977 SUPERFAMILY SSF81301 37 302 7.96E-88 T 13-09-2016 THL1_RS26185 2a61256285eed7374624c0d1e489b1b9 977 Hamap MF_00802 Glutamate-ammonia-ligase adenylyltransferase [glnE]. 41 977 19.968 T 13-09-2016 IPR023057 Glutamate-ammonia-ligase adenylyltransferase GO:0008882 THL1_RS23405 859e5d9eff3840688ba966489a74aa99 231 SUPERFAMILY SSF53335 1 221 2.99E-28 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS23405 859e5d9eff3840688ba966489a74aa99 231 PANTHER PTHR10108 1 222 1.2E-50 T 13-09-2016 THL1_RS23405 859e5d9eff3840688ba966489a74aa99 231 Gene3D G3DSA:3.40.50.150 19 215 9.5E-24 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS23405 859e5d9eff3840688ba966489a74aa99 231 PANTHER PTHR10108:SF855 1 222 1.2E-50 T 13-09-2016 THL1_RS23405 859e5d9eff3840688ba966489a74aa99 231 Pfam PF13649 Methyltransferase domain 55 150 4.0E-14 T 13-09-2016 THL1_RS01635 aeda84ec839a0900eaeae857139dfd09 666 PANTHER PTHR11624 329 665 0.0 T 13-09-2016 IPR033247 Transketolase family THL1_RS01635 aeda84ec839a0900eaeae857139dfd09 666 ProSitePatterns PS00802 Transketolase signature 2. 468 484 - T 13-09-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 THL1_RS01635 aeda84ec839a0900eaeae857139dfd09 666 Pfam PF02780 Transketolase, C-terminal domain 541 656 6.6E-16 T 13-09-2016 IPR033248 Transketolase, C-terminal domain THL1_RS01635 aeda84ec839a0900eaeae857139dfd09 666 PANTHER PTHR11624:SF1 329 665 0.0 T 13-09-2016 THL1_RS01635 aeda84ec839a0900eaeae857139dfd09 666 SUPERFAMILY SSF52518 335 526 8.32E-68 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS01635 aeda84ec839a0900eaeae857139dfd09 666 Gene3D G3DSA:3.40.50.970 5 322 2.3E-132 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS01635 aeda84ec839a0900eaeae857139dfd09 666 PANTHER PTHR11624 1 310 0.0 T 13-09-2016 IPR033247 Transketolase family THL1_RS01635 aeda84ec839a0900eaeae857139dfd09 666 Gene3D G3DSA:3.40.50.920 539 665 2.9E-49 T 13-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THL1_RS01635 aeda84ec839a0900eaeae857139dfd09 666 SMART SM00861 355 526 3.4E-68 T 13-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain THL1_RS01635 aeda84ec839a0900eaeae857139dfd09 666 Gene3D G3DSA:3.40.50.970 328 533 1.0E-78 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS01635 aeda84ec839a0900eaeae857139dfd09 666 TIGRFAM TIGR00232 tktlase_bact: transketolase 6 664 0.0 T 13-09-2016 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 THL1_RS01635 aeda84ec839a0900eaeae857139dfd09 666 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 5 334 2.2E-168 T 13-09-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 THL1_RS01635 aeda84ec839a0900eaeae857139dfd09 666 ProSitePatterns PS00801 Transketolase signature 1. 12 32 - T 13-09-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 THL1_RS01635 aeda84ec839a0900eaeae857139dfd09 666 SUPERFAMILY SSF52922 534 665 7.72E-43 T 13-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THL1_RS01635 aeda84ec839a0900eaeae857139dfd09 666 SUPERFAMILY SSF52518 5 329 4.29E-120 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS01635 aeda84ec839a0900eaeae857139dfd09 666 Pfam PF02779 Transketolase, pyrimidine binding domain 354 526 7.9E-45 T 13-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain THL1_RS01635 aeda84ec839a0900eaeae857139dfd09 666 PANTHER PTHR11624:SF1 1 310 0.0 T 13-09-2016 THL1_RS05860 b6799e0e9ea49c68b01f857d0d96bdd8 353 PANTHER PTHR33529:SF1 1 352 8.7E-132 T 13-09-2016 THL1_RS05860 b6799e0e9ea49c68b01f857d0d96bdd8 353 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 351 5.5E-64 T 13-09-2016 IPR005495 Permease LptG/LptF-related GO:0016021 THL1_RS05860 b6799e0e9ea49c68b01f857d0d96bdd8 353 PANTHER PTHR33529 1 352 8.7E-132 T 13-09-2016 THL1_RS05860 b6799e0e9ea49c68b01f857d0d96bdd8 353 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 4 351 1.5E-129 T 13-09-2016 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 THL1_RS23945 755f5db66dc8215641e453d201d2d97c 423 SUPERFAMILY SSF53335 24 363 1.54E-90 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS23945 755f5db66dc8215641e453d201d2d97c 423 PANTHER PTHR10108:SF795 65 323 5.2E-116 T 13-09-2016 THL1_RS23945 755f5db66dc8215641e453d201d2d97c 423 PANTHER PTHR10108:SF795 344 411 5.2E-116 T 13-09-2016 THL1_RS23945 755f5db66dc8215641e453d201d2d97c 423 PIRSF PIRSF003085 20 420 4.6E-130 T 13-09-2016 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 THL1_RS23945 755f5db66dc8215641e453d201d2d97c 423 PANTHER PTHR10108 65 323 5.2E-116 T 13-09-2016 THL1_RS23945 755f5db66dc8215641e453d201d2d97c 423 PANTHER PTHR10108 344 411 5.2E-116 T 13-09-2016 THL1_RS23945 755f5db66dc8215641e453d201d2d97c 423 Gene3D G3DSA:3.40.50.150 131 408 1.9E-96 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS23945 755f5db66dc8215641e453d201d2d97c 423 Pfam PF02353 Mycolic acid cyclopropane synthetase 136 404 5.8E-89 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS07730 756cb3b26e51fc2d65c9081d790581be 337 PANTHER PTHR11019:SF54 35 334 3.2E-56 T 13-09-2016 THL1_RS07730 756cb3b26e51fc2d65c9081d790581be 337 SMART SM00342 241 326 4.1E-22 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS07730 756cb3b26e51fc2d65c9081d790581be 337 SUPERFAMILY SSF46689 225 275 4.44E-6 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS07730 756cb3b26e51fc2d65c9081d790581be 337 Pfam PF14525 AraC-binding-like domain 22 204 1.3E-32 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS07730 756cb3b26e51fc2d65c9081d790581be 337 PANTHER PTHR11019 35 334 3.2E-56 T 13-09-2016 THL1_RS07730 756cb3b26e51fc2d65c9081d790581be 337 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 278 322 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS07730 756cb3b26e51fc2d65c9081d790581be 337 Gene3D G3DSA:1.10.10.60 226 278 8.4E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS07730 756cb3b26e51fc2d65c9081d790581be 337 Gene3D G3DSA:1.10.10.60 279 324 4.2E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS07730 756cb3b26e51fc2d65c9081d790581be 337 SUPERFAMILY SSF46689 282 328 5.82E-6 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS07730 756cb3b26e51fc2d65c9081d790581be 337 Pfam PF12833 Helix-turn-helix domain 249 328 3.6E-24 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS07445 81c636ddc6b73abab8da6fe454926c11 299 Pfam PF13522 Glutamine amidotransferase domain 142 270 2.8E-20 T 13-09-2016 THL1_RS07445 81c636ddc6b73abab8da6fe454926c11 299 PANTHER PTHR11907:SF0 113 277 8.7E-33 T 13-09-2016 THL1_RS07445 81c636ddc6b73abab8da6fe454926c11 299 PANTHER PTHR11907:SF0 1 55 8.7E-33 T 13-09-2016 THL1_RS07445 81c636ddc6b73abab8da6fe454926c11 299 PANTHER PTHR11907 113 277 8.7E-33 T 13-09-2016 THL1_RS07445 81c636ddc6b73abab8da6fe454926c11 299 PANTHER PTHR11907 1 55 8.7E-33 T 13-09-2016 THL1_RS07445 81c636ddc6b73abab8da6fe454926c11 299 SUPERFAMILY SSF56235 117 297 1.19E-46 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS07445 81c636ddc6b73abab8da6fe454926c11 299 SUPERFAMILY SSF56235 2 44 1.19E-46 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS07445 81c636ddc6b73abab8da6fe454926c11 299 Gene3D G3DSA:3.60.20.10 2 44 6.7E-59 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS07445 81c636ddc6b73abab8da6fe454926c11 299 Gene3D G3DSA:3.60.20.10 116 298 6.7E-59 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS05975 105e31a0fbdd1b8ae3d8a5a28b8a3a54 252 Pfam PF13424 Tetratricopeptide repeat 105 171 4.3E-8 T 13-09-2016 THL1_RS05975 105e31a0fbdd1b8ae3d8a5a28b8a3a54 252 Gene3D G3DSA:1.25.40.10 38 213 3.5E-30 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS05975 105e31a0fbdd1b8ae3d8a5a28b8a3a54 252 PANTHER PTHR23083 38 252 5.2E-25 T 13-09-2016 THL1_RS05975 105e31a0fbdd1b8ae3d8a5a28b8a3a54 252 SUPERFAMILY SSF81901 39 215 6.54E-24 T 13-09-2016 THL1_RS05975 105e31a0fbdd1b8ae3d8a5a28b8a3a54 252 TIGRFAM TIGR02521 type_IV_pilW: type IV pilus biogenesis/stability protein PilW 8 239 2.1E-75 T 13-09-2016 IPR013360 Pilus biogenesis/stability type IV, PilW THL1_RS05975 105e31a0fbdd1b8ae3d8a5a28b8a3a54 252 SMART SM00028 71 104 73.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS05975 105e31a0fbdd1b8ae3d8a5a28b8a3a54 252 SMART SM00028 140 173 0.0015 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS05975 105e31a0fbdd1b8ae3d8a5a28b8a3a54 252 SMART SM00028 174 207 30.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS05975 105e31a0fbdd1b8ae3d8a5a28b8a3a54 252 SMART SM00028 37 70 0.29 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS09530 cdf6c7e709abb233d15961fb58df2b31 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 71 1.2E-12 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS09530 cdf6c7e709abb233d15961fb58df2b31 219 PANTHER PTHR11751 192 215 3.9E-14 T 13-09-2016 THL1_RS09530 cdf6c7e709abb233d15961fb58df2b31 219 SUPERFAMILY SSF46785 5 89 8.56E-16 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09530 cdf6c7e709abb233d15961fb58df2b31 219 SMART SM00345 13 71 5.0E-10 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS09530 cdf6c7e709abb233d15961fb58df2b31 219 Pfam PF07729 FCD domain 102 201 3.9E-10 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS09530 cdf6c7e709abb233d15961fb58df2b31 219 PANTHER PTHR11751:SF416 11 73 3.9E-14 T 13-09-2016 THL1_RS09530 cdf6c7e709abb233d15961fb58df2b31 219 Gene3D G3DSA:1.20.120.530 79 216 3.4E-9 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS09530 cdf6c7e709abb233d15961fb58df2b31 219 Gene3D G3DSA:1.10.10.10 5 72 9.2E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09530 cdf6c7e709abb233d15961fb58df2b31 219 SUPERFAMILY SSF48008 94 211 1.96E-9 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS09530 cdf6c7e709abb233d15961fb58df2b31 219 PANTHER PTHR11751 11 73 3.9E-14 T 13-09-2016 THL1_RS09530 cdf6c7e709abb233d15961fb58df2b31 219 PANTHER PTHR11751:SF416 192 215 3.9E-14 T 13-09-2016 THL1_RS20020 cc11098f5a7d050ff4dc293f3017cc97 461 Pfam PF10996 Beta-Casp domain 249 366 1.1E-24 T 13-09-2016 IPR022712 Beta-Casp domain THL1_RS20020 cc11098f5a7d050ff4dc293f3017cc97 461 PANTHER PTHR11203 5 453 1.9E-113 T 13-09-2016 THL1_RS20020 cc11098f5a7d050ff4dc293f3017cc97 461 SUPERFAMILY SSF56281 5 443 2.75E-129 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS20020 cc11098f5a7d050ff4dc293f3017cc97 461 SMART SM00849 15 238 3.9E-17 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS20020 cc11098f5a7d050ff4dc293f3017cc97 461 SMART SM01027 249 368 8.2E-49 T 13-09-2016 IPR022712 Beta-Casp domain THL1_RS20020 cc11098f5a7d050ff4dc293f3017cc97 461 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 382 443 4.6E-14 T 13-09-2016 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain THL1_RS20020 cc11098f5a7d050ff4dc293f3017cc97 461 PANTHER PTHR11203:SF11 5 453 1.9E-113 T 13-09-2016 THL1_RS20020 cc11098f5a7d050ff4dc293f3017cc97 461 Pfam PF00753 Metallo-beta-lactamase superfamily 18 209 3.2E-18 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS20020 cc11098f5a7d050ff4dc293f3017cc97 461 Gene3D G3DSA:3.60.15.10 137 258 7.7E-53 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS20020 cc11098f5a7d050ff4dc293f3017cc97 461 Gene3D G3DSA:3.60.15.10 4 102 7.7E-53 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS04070 c2fd34dd2ea273b413cba61cefb280cb 504 SUPERFAMILY SSF53098 156 294 2.16E-5 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS04070 c2fd34dd2ea273b413cba61cefb280cb 504 PANTHER PTHR35004:SF2 1 449 5.8E-119 T 13-09-2016 THL1_RS04070 c2fd34dd2ea273b413cba61cefb280cb 504 Gene3D G3DSA:3.30.420.10 157 294 1.5E-7 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS04070 c2fd34dd2ea273b413cba61cefb280cb 504 PANTHER PTHR35004 1 449 5.8E-119 T 13-09-2016 THL1_RS04070 c2fd34dd2ea273b413cba61cefb280cb 504 Pfam PF00665 Integrase core domain 129 259 1.7E-17 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS08865 c2fd34dd2ea273b413cba61cefb280cb 504 SUPERFAMILY SSF53098 156 294 2.16E-5 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS08865 c2fd34dd2ea273b413cba61cefb280cb 504 PANTHER PTHR35004:SF2 1 449 5.8E-119 T 13-09-2016 THL1_RS08865 c2fd34dd2ea273b413cba61cefb280cb 504 Gene3D G3DSA:3.30.420.10 157 294 1.5E-7 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS08865 c2fd34dd2ea273b413cba61cefb280cb 504 PANTHER PTHR35004 1 449 5.8E-119 T 13-09-2016 THL1_RS08865 c2fd34dd2ea273b413cba61cefb280cb 504 Pfam PF00665 Integrase core domain 129 259 1.7E-17 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS17995 4c332c09a1e2e2f5d337b8f9d21e7c8e 213 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 19 209 43.625 T 13-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THL1_RS17995 4c332c09a1e2e2f5d337b8f9d21e7c8e 213 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 106 117 - T 13-09-2016 IPR018215 ClpP, Ser active site THL1_RS17995 4c332c09a1e2e2f5d337b8f9d21e7c8e 213 PANTHER PTHR10381 3 210 2.5E-138 T 13-09-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA THL1_RS17995 4c332c09a1e2e2f5d337b8f9d21e7c8e 213 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 19 208 2.3E-104 T 13-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THL1_RS17995 4c332c09a1e2e2f5d337b8f9d21e7c8e 213 Pfam PF00574 Clp protease 29 208 1.9E-86 T 13-09-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA THL1_RS17995 4c332c09a1e2e2f5d337b8f9d21e7c8e 213 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 128 141 - T 13-09-2016 IPR033135 ClpP, histidine active site THL1_RS17995 4c332c09a1e2e2f5d337b8f9d21e7c8e 213 PRINTS PR00127 Clp protease catalytic subunit P signature 75 95 9.2E-51 T 13-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THL1_RS17995 4c332c09a1e2e2f5d337b8f9d21e7c8e 213 PRINTS PR00127 Clp protease catalytic subunit P signature 127 146 9.2E-51 T 13-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THL1_RS17995 4c332c09a1e2e2f5d337b8f9d21e7c8e 213 PRINTS PR00127 Clp protease catalytic subunit P signature 184 203 9.2E-51 T 13-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THL1_RS17995 4c332c09a1e2e2f5d337b8f9d21e7c8e 213 PRINTS PR00127 Clp protease catalytic subunit P signature 106 123 9.2E-51 T 13-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THL1_RS17995 4c332c09a1e2e2f5d337b8f9d21e7c8e 213 PRINTS PR00127 Clp protease catalytic subunit P signature 35 50 9.2E-51 T 13-09-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THL1_RS17995 4c332c09a1e2e2f5d337b8f9d21e7c8e 213 Gene3D G3DSA:3.90.226.10 19 209 2.8E-89 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS17995 4c332c09a1e2e2f5d337b8f9d21e7c8e 213 PANTHER PTHR10381:SF22 3 210 2.5E-138 T 13-09-2016 THL1_RS17995 4c332c09a1e2e2f5d337b8f9d21e7c8e 213 SUPERFAMILY SSF52096 27 210 6.04E-73 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS00055 220fad64c241608390e7fb33370aafde 176 SUPERFAMILY SSF56784 1 175 1.76E-44 T 13-09-2016 IPR023214 HAD-like domain THL1_RS00055 220fad64c241608390e7fb33370aafde 176 PANTHER PTHR23133:SF7 2 174 1.6E-95 T 13-09-2016 THL1_RS00055 220fad64c241608390e7fb33370aafde 176 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 2 145 1.1E-42 T 13-09-2016 IPR006543 Histidinol-phosphate phosphatase GO:0016791 THL1_RS00055 220fad64c241608390e7fb33370aafde 176 Gene3D G3DSA:3.40.50.1000 1 174 2.4E-52 T 13-09-2016 IPR023214 HAD-like domain THL1_RS00055 220fad64c241608390e7fb33370aafde 176 PIRSF PIRSF004682 1 174 1.1E-51 T 13-09-2016 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 THL1_RS00055 220fad64c241608390e7fb33370aafde 176 Pfam PF13242 HAD-hyrolase-like 99 168 1.8E-13 T 13-09-2016 THL1_RS00055 220fad64c241608390e7fb33370aafde 176 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 2 146 1.1E-34 T 13-09-2016 IPR006549 HAD-superfamily hydrolase,subfamily IIIA THL1_RS00055 220fad64c241608390e7fb33370aafde 176 PANTHER PTHR23133 2 174 1.6E-95 T 13-09-2016 THL1_RS21365 81c79bb22354fce85f087c8b32e8a53f 461 SMART SM00387 357 461 3.6E-29 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS21365 81c79bb22354fce85f087c8b32e8a53f 461 Gene3D G3DSA:1.10.287.130 236 305 1.0E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS21365 81c79bb22354fce85f087c8b32e8a53f 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 419 7.0E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS21365 81c79bb22354fce85f087c8b32e8a53f 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 405 7.0E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS21365 81c79bb22354fce85f087c8b32e8a53f 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 7.0E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS21365 81c79bb22354fce85f087c8b32e8a53f 461 Pfam PF00672 HAMP domain 175 239 1.5E-9 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS21365 81c79bb22354fce85f087c8b32e8a53f 461 PANTHER PTHR24423 107 127 2.3E-66 T 13-09-2016 THL1_RS21365 81c79bb22354fce85f087c8b32e8a53f 461 Pfam PF00512 His Kinase A (phospho-acceptor) domain 245 309 7.2E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS21365 81c79bb22354fce85f087c8b32e8a53f 461 Pfam PF08521 Two-component sensor kinase N-terminal 21 166 4.8E-42 T 13-09-2016 IPR013727 Two-component sensor kinase, N-terminal THL1_RS21365 81c79bb22354fce85f087c8b32e8a53f 461 PANTHER PTHR24423:SF474 185 459 2.3E-66 T 13-09-2016 THL1_RS21365 81c79bb22354fce85f087c8b32e8a53f 461 PANTHER PTHR24423:SF474 107 127 2.3E-66 T 13-09-2016 THL1_RS21365 81c79bb22354fce85f087c8b32e8a53f 461 PANTHER PTHR24423 185 459 2.3E-66 T 13-09-2016 THL1_RS21365 81c79bb22354fce85f087c8b32e8a53f 461 SUPERFAMILY SSF47384 227 309 6.47E-19 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS21365 81c79bb22354fce85f087c8b32e8a53f 461 SUPERFAMILY SSF55874 298 459 6.16E-33 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS21365 81c79bb22354fce85f087c8b32e8a53f 461 Gene3D G3DSA:3.30.565.10 319 459 6.2E-34 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS21365 81c79bb22354fce85f087c8b32e8a53f 461 SMART SM00388 244 309 1.2E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS21365 81c79bb22354fce85f087c8b32e8a53f 461 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 460 2.5E-19 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS12270 94c829680c7948a27af1030bf885164b 329 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 10 328 23.635 T 13-09-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 THL1_RS12270 94c829680c7948a27af1030bf885164b 329 PANTHER PTHR11432 1 326 2.0E-229 T 13-09-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 THL1_RS12270 94c829680c7948a27af1030bf885164b 329 Pfam PF00146 NADH dehydrogenase 17 321 9.3E-117 T 13-09-2016 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 THL1_RS12270 94c829680c7948a27af1030bf885164b 329 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 212 225 - T 13-09-2016 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 THL1_RS12270 94c829680c7948a27af1030bf885164b 329 PANTHER PTHR11432:SF8 1 326 2.0E-229 T 13-09-2016 THL1_RS17045 e4069aefd48e3cb62ecc8b9e639ccf4f 284 SUPERFAMILY SSF47413 36 87 1.72E-5 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS17045 e4069aefd48e3cb62ecc8b9e639ccf4f 284 PANTHER PTHR35010:SF2 8 284 2.7E-84 T 13-09-2016 THL1_RS17045 e4069aefd48e3cb62ecc8b9e639ccf4f 284 PANTHER PTHR35010 8 284 2.7E-84 T 13-09-2016 THL1_RS17045 e4069aefd48e3cb62ecc8b9e639ccf4f 284 Gene3D G3DSA:1.10.260.40 11 88 2.6E-14 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS17045 e4069aefd48e3cb62ecc8b9e639ccf4f 284 SMART SM00530 17 89 1.2E-5 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS17045 e4069aefd48e3cb62ecc8b9e639ccf4f 284 Pfam PF13560 Helix-turn-helix domain 13 92 1.1E-16 T 13-09-2016 THL1_RS18210 02076f4da900c9288308fdee15f48dba 66 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 1 43 8.2E-7 T 13-09-2016 IPR019239 Bacterial antitoxin of type II TA system, VapB THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 SMART SM00388 399 464 1.1E-24 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 SUPERFAMILY SSF55874 453 624 6.42E-31 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 Gene3D G3DSA:3.40.50.2300 641 769 7.5E-28 T 13-09-2016 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 SMART SM00448 643 762 1.0E-19 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 SMART SM00448 792 908 7.5E-32 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 Pfam PF00512 His Kinase A (phospho-acceptor) domain 399 464 7.3E-20 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 Gene3D G3DSA:3.40.50.2300 790 917 3.7E-40 T 13-09-2016 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 Pfam PF00072 Response regulator receiver domain 646 761 2.1E-19 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 Pfam PF00072 Response regulator receiver domain 794 908 2.4E-22 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 PRINTS PR00344 Bacterial sensor protein C-terminal signature 551 565 8.7E-6 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 PRINTS PR00344 Bacterial sensor protein C-terminal signature 586 604 8.7E-6 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 PRINTS PR00344 Bacterial sensor protein C-terminal signature 610 623 8.7E-6 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 Gene3D G3DSA:1.10.287.130 396 460 3.1E-17 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 PANTHER PTHR24423 376 629 1.4E-112 T 13-09-2016 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 PANTHER PTHR24423 105 141 1.4E-112 T 13-09-2016 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 PANTHER PTHR24423 776 919 1.4E-112 T 13-09-2016 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 SUPERFAMILY SSF52172 642 769 8.82E-28 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 Pfam PF07696 7TMR-DISM extracellular 2 30 161 1.0E-20 T 13-09-2016 IPR011622 7TM-DISM receptor, extracellular domain, type 2 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 SUPERFAMILY SSF47384 390 465 1.06E-19 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 511 625 1.1E-15 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 Pfam PF07695 7TM diverse intracellular signalling 173 375 5.1E-23 T 13-09-2016 IPR011623 7TM-DISM receptor, extracellular domain, type 1 THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 SUPERFAMILY SSF52172 790 911 2.56E-35 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 Gene3D G3DSA:3.30.565.10 465 626 5.5E-31 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS25505 925a2e8376a4636c829237f424e5851d 925 SMART SM00387 511 626 6.7E-17 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 SUPERFAMILY SSF52540 133 350 1.04E-33 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 PANTHER PTHR10799 164 352 5.9E-277 T 13-09-2016 THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 Gene3D G3DSA:3.40.50.300 156 340 8.0E-16 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 PANTHER PTHR10799 782 823 5.9E-277 T 13-09-2016 THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 Gene3D G3DSA:3.40.50.300 457 613 3.1E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 Pfam PF00176 SNF2 family N-terminal domain 119 343 1.6E-13 T 13-09-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 SMART SM00487 150 340 5.1E-16 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 PANTHER PTHR10799 394 677 5.9E-277 T 13-09-2016 THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 PANTHER PTHR10799 875 949 5.9E-277 T 13-09-2016 THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 PANTHER PTHR10799:SF610 394 677 5.9E-277 T 13-09-2016 THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 SMART SM00490 501 585 3.0E-15 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 Pfam PF12137 RNA polymerase recycling family C-terminal 589 947 9.5E-138 T 13-09-2016 IPR022737 RNA polymerase recycling, bacterial, C-terminal GO:0016817 THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 Pfam PF00271 Helicase conserved C-terminal domain 476 585 1.9E-12 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 PANTHER PTHR10799:SF610 875 949 5.9E-277 T 13-09-2016 THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 PANTHER PTHR10799:SF610 782 823 5.9E-277 T 13-09-2016 THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 PANTHER PTHR10799:SF610 164 352 5.9E-277 T 13-09-2016 THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 Hamap MF_01821 RNA polymerase-associated protein RapA [rapA]. 3 949 69.388 T 13-09-2016 IPR023949 RNA polymerase-associated protein RapA GO:0006355 THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 SUPERFAMILY SSF52540 464 631 8.54E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08605 e027d319ae6cd323a00406dc7c79b9e4 949 SUPERFAMILY SSF52540 271 335 8.54E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15850 a17cf4eaf5694d0f96e4dd3f1e978b93 75 Gene3D G3DSA:3.30.300.30 19 66 2.4E-9 T 13-09-2016 THL1_RS15850 a17cf4eaf5694d0f96e4dd3f1e978b93 75 PANTHER PTHR24096:SF240 1 54 2.3E-17 T 13-09-2016 THL1_RS15850 a17cf4eaf5694d0f96e4dd3f1e978b93 75 Pfam PF00501 AMP-binding enzyme 1 26 1.7E-5 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS15850 a17cf4eaf5694d0f96e4dd3f1e978b93 75 SUPERFAMILY SSF56801 2 55 9.94E-18 T 13-09-2016 THL1_RS15850 a17cf4eaf5694d0f96e4dd3f1e978b93 75 PANTHER PTHR24096 1 54 2.3E-17 T 13-09-2016 THL1_RS17860 45c317bbaa1115e938be854679a906d5 253 SMART SM00479 10 184 1.8E-50 T 13-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III THL1_RS17860 45c317bbaa1115e938be854679a906d5 253 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 10 227 4.7E-65 T 13-09-2016 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS17860 45c317bbaa1115e938be854679a906d5 253 SUPERFAMILY SSF53098 9 185 2.75E-55 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS17860 45c317bbaa1115e938be854679a906d5 253 PANTHER PTHR30231 10 239 3.1E-116 T 13-09-2016 THL1_RS17860 45c317bbaa1115e938be854679a906d5 253 Gene3D G3DSA:3.30.420.10 7 185 2.6E-63 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS17860 45c317bbaa1115e938be854679a906d5 253 Pfam PF00929 Exonuclease 12 175 2.1E-38 T 13-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III THL1_RS17860 45c317bbaa1115e938be854679a906d5 253 PANTHER PTHR30231:SF0 10 239 3.1E-116 T 13-09-2016 THL1_RS17860 45c317bbaa1115e938be854679a906d5 253 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 10 245 1.2E-90 T 13-09-2016 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 SUPERFAMILY SSF52172 668 788 4.84E-35 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 452 3.4E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 PRINTS PR00344 Bacterial sensor protein C-terminal signature 497 510 3.4E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 491 3.4E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 466 3.4E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 SMART SM00448 668 784 1.0E-36 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 Pfam PF01627 Hpt domain 833 913 2.4E-10 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 SUPERFAMILY SSF47384 270 350 3.14E-22 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 SUPERFAMILY SSF47226 767 780 9.81E-21 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 SUPERFAMILY SSF47226 813 910 9.81E-21 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 Gene3D G3DSA:1.20.120.160 808 912 8.4E-16 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 SUPERFAMILY SSF52172 526 650 4.98E-5 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 PANTHER PTHR24423 186 240 2.6E-147 T 13-09-2016 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 PANTHER PTHR24423 280 516 2.6E-147 T 13-09-2016 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 PANTHER PTHR24423 16 47 2.6E-147 T 13-09-2016 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 PANTHER PTHR24423 650 827 2.6E-147 T 13-09-2016 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 SMART SM00073 824 920 3.8E-10 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 Pfam PF09984 Uncharacterised signal transduction histidine kinase domain (DUF2222) 37 168 3.5E-19 T 13-09-2016 IPR019247 Histidine kinase BarA, N-terminal THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 SMART SM00387 396 513 4.2E-39 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 SUPERFAMILY SSF158472 192 241 2.09E-5 T 13-09-2016 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 Gene3D G3DSA:3.40.50.2300 665 788 3.3E-37 T 13-09-2016 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 SUPERFAMILY SSF55874 338 510 1.83E-46 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 Pfam PF00672 HAMP domain 173 240 1.8E-11 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 Gene3D G3DSA:1.10.287.130 276 345 1.3E-19 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 SMART SM00388 284 349 5.0E-26 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 SMART SM00304 192 244 6.5E-10 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 Pfam PF00072 Response regulator receiver domain 671 784 1.1E-26 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 Pfam PF00512 His Kinase A (phospho-acceptor) domain 285 349 5.8E-22 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 Gene3D G3DSA:3.30.565.10 350 513 4.4E-47 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS22315 84b4d6ebfcdbaa192f17bbaf1494c020 920 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 396 512 1.8E-28 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS16620 4ee907d5fdf29bb5d50f866178655a90 471 PANTHER PTHR30386 23 146 3.1E-92 T 13-09-2016 THL1_RS16620 4ee907d5fdf29bb5d50f866178655a90 471 Pfam PF13533 Biotin-lipoyl like 95 133 5.7E-7 T 13-09-2016 THL1_RS16620 4ee907d5fdf29bb5d50f866178655a90 471 PANTHER PTHR30386:SF8 182 471 3.1E-92 T 13-09-2016 THL1_RS16620 4ee907d5fdf29bb5d50f866178655a90 471 Pfam PF13437 HlyD family secretion protein 323 438 6.3E-18 T 13-09-2016 THL1_RS16620 4ee907d5fdf29bb5d50f866178655a90 471 PANTHER PTHR30386:SF8 23 146 3.1E-92 T 13-09-2016 THL1_RS16620 4ee907d5fdf29bb5d50f866178655a90 471 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 52 471 4.0E-119 T 13-09-2016 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 THL1_RS16620 4ee907d5fdf29bb5d50f866178655a90 471 PANTHER PTHR30386 182 471 3.1E-92 T 13-09-2016 THL1_RS16620 4ee907d5fdf29bb5d50f866178655a90 471 Gene3D G3DSA:2.40.50.100 95 125 6.4E-17 T 13-09-2016 THL1_RS16620 4ee907d5fdf29bb5d50f866178655a90 471 Gene3D G3DSA:2.40.50.100 320 355 6.4E-17 T 13-09-2016 THL1_RS16620 4ee907d5fdf29bb5d50f866178655a90 471 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 61 84 4.9E-55 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS16620 4ee907d5fdf29bb5d50f866178655a90 471 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 335 356 4.9E-55 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS16620 4ee907d5fdf29bb5d50f866178655a90 471 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 450 470 4.9E-55 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS16620 4ee907d5fdf29bb5d50f866178655a90 471 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 368 392 4.9E-55 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS16620 4ee907d5fdf29bb5d50f866178655a90 471 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 103 123 4.9E-55 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS16620 4ee907d5fdf29bb5d50f866178655a90 471 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 392 415 4.9E-55 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS16620 4ee907d5fdf29bb5d50f866178655a90 471 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 435 450 4.9E-55 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS19405 79e95ffaa82c1c1f3f6cd238e2fb0970 162 PANTHER PTHR30009:SF6 1 157 4.2E-47 T 13-09-2016 THL1_RS19405 79e95ffaa82c1c1f3f6cd238e2fb0970 162 PANTHER PTHR30009 1 157 4.2E-47 T 13-09-2016 THL1_RS19405 79e95ffaa82c1c1f3f6cd238e2fb0970 162 Pfam PF03918 Cytochrome C biogenesis protein 9 152 1.5E-56 T 13-09-2016 IPR005616 CcmH/CycL/Ccl2/NrfF family THL1_RS12655 6b4a27205c3e8f15c9990dd657ac773d 343 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 30 79 1.2E-8 T 13-09-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain THL1_RS12655 6b4a27205c3e8f15c9990dd657ac773d 343 Pfam PF01610 Transposase 95 334 1.8E-67 T 13-09-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain THL1_RS12655 6b4a27205c3e8f15c9990dd657ac773d 343 PANTHER PTHR33498 1 330 4.6E-32 T 13-09-2016 THL1_RS12655 6b4a27205c3e8f15c9990dd657ac773d 343 PANTHER PTHR33498:SF1 1 330 4.6E-32 T 13-09-2016 THL1_RS17410 6b4a27205c3e8f15c9990dd657ac773d 343 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 30 79 1.2E-8 T 13-09-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain THL1_RS17410 6b4a27205c3e8f15c9990dd657ac773d 343 Pfam PF01610 Transposase 95 334 1.8E-67 T 13-09-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain THL1_RS17410 6b4a27205c3e8f15c9990dd657ac773d 343 PANTHER PTHR33498 1 330 4.6E-32 T 13-09-2016 THL1_RS17410 6b4a27205c3e8f15c9990dd657ac773d 343 PANTHER PTHR33498:SF1 1 330 4.6E-32 T 13-09-2016 THL1_RS05740 6b4a27205c3e8f15c9990dd657ac773d 343 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 30 79 1.2E-8 T 13-09-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain THL1_RS05740 6b4a27205c3e8f15c9990dd657ac773d 343 Pfam PF01610 Transposase 95 334 1.8E-67 T 13-09-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain THL1_RS05740 6b4a27205c3e8f15c9990dd657ac773d 343 PANTHER PTHR33498 1 330 4.6E-32 T 13-09-2016 THL1_RS05740 6b4a27205c3e8f15c9990dd657ac773d 343 PANTHER PTHR33498:SF1 1 330 4.6E-32 T 13-09-2016 THL1_RS25160 6b4a27205c3e8f15c9990dd657ac773d 343 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 30 79 1.2E-8 T 13-09-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain THL1_RS25160 6b4a27205c3e8f15c9990dd657ac773d 343 Pfam PF01610 Transposase 95 334 1.8E-67 T 13-09-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain THL1_RS25160 6b4a27205c3e8f15c9990dd657ac773d 343 PANTHER PTHR33498 1 330 4.6E-32 T 13-09-2016 THL1_RS25160 6b4a27205c3e8f15c9990dd657ac773d 343 PANTHER PTHR33498:SF1 1 330 4.6E-32 T 13-09-2016 THL1_RS17925 6b4a27205c3e8f15c9990dd657ac773d 343 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 30 79 1.2E-8 T 13-09-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain THL1_RS17925 6b4a27205c3e8f15c9990dd657ac773d 343 Pfam PF01610 Transposase 95 334 1.8E-67 T 13-09-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain THL1_RS17925 6b4a27205c3e8f15c9990dd657ac773d 343 PANTHER PTHR33498 1 330 4.6E-32 T 13-09-2016 THL1_RS17925 6b4a27205c3e8f15c9990dd657ac773d 343 PANTHER PTHR33498:SF1 1 330 4.6E-32 T 13-09-2016 THL1_RS21325 4baa21c91ad8b99408cfd39d288d5167 196 Pfam PF03873 Anti sigma-E protein RseA, C-terminal domain 123 177 1.3E-10 T 13-09-2016 IPR005573 Anti sigma-E protein RseA, C-terminal THL1_RS21325 4baa21c91ad8b99408cfd39d288d5167 196 PANTHER PTHR38104 1 196 2.9E-39 T 13-09-2016 THL1_RS21325 4baa21c91ad8b99408cfd39d288d5167 196 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 7 74 1.1E-12 T 13-09-2016 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 THL1_RS21325 4baa21c91ad8b99408cfd39d288d5167 196 SUPERFAMILY SSF89069 6 71 2.35E-13 T 13-09-2016 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 Gene3D G3DSA:3.30.470.30 130 262 5.6E-53 T 13-09-2016 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 PANTHER PTHR23389 10 555 1.6E-201 T 13-09-2016 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 SUPERFAMILY SSF56091 4 326 1.98E-118 T 13-09-2016 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 417 456 1.6E-10 T 13-09-2016 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 Gene3D G3DSA:1.10.150.20 457 525 1.2E-25 T 13-09-2016 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 SUPERFAMILY SSF50249 328 410 1.27E-28 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 Gene3D G3DSA:1.10.287.610 3 70 9.4E-30 T 13-09-2016 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 332 408 2.7E-35 T 13-09-2016 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 Gene3D G3DSA:2.40.50.140 330 401 9.9E-35 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 Pfam PF12826 Helix-hairpin-helix motif 532 595 7.8E-20 T 13-09-2016 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 PANTHER PTHR23389:SF9 10 555 1.6E-201 T 13-09-2016 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 126 155 - T 13-09-2016 IPR018239 NAD-dependent DNA ligase, active site THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 SMART SM00278 468 487 32.0 T 13-09-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 SMART SM00278 659 678 1800.0 T 13-09-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 SMART SM00278 534 553 120.0 T 13-09-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 341 356 - T 13-09-2016 IPR033136 NAD-dependent DNA ligase, conserved site THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 Gene3D G3DSA:1.10.150.20 526 607 1.2E-25 T 13-09-2016 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 Gene3D G3DSA:1.10.150.20 620 704 6.7E-10 T 13-09-2016 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 SUPERFAMILY SSF52113 712 783 1.78E-16 T 13-09-2016 IPR001357 BRCT domain THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 SMART SM00532 6 470 3.2E-257 T 13-09-2016 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 14 607 5.0E-219 T 13-09-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 8 328 3.5E-125 T 13-09-2016 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 Hamap MF_01588 DNA ligase [ligA]. 5 785 52.123 T 13-09-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 SUPERFAMILY SSF47781 616 703 3.41E-5 T 13-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 SMART SM00292 711 788 2.4E-7 T 13-09-2016 IPR001357 BRCT domain THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 SUPERFAMILY SSF47781 413 605 7.78E-50 T 13-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 Gene3D G3DSA:3.40.50.10190 713 786 1.0E-22 T 13-09-2016 IPR001357 BRCT domain THL1_RS09545 3aa845dfa7b26a03d1b59b14f0fc775d 789 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 711 783 2.4E-10 T 13-09-2016 IPR001357 BRCT domain THL1_RS23245 52075cf7beb4c6dbda42b639095dc9ce 256 PANTHER PTHR10434 10 191 4.1E-66 T 13-09-2016 THL1_RS23245 52075cf7beb4c6dbda42b639095dc9ce 256 PANTHER PTHR10434 208 245 4.1E-66 T 13-09-2016 THL1_RS23245 52075cf7beb4c6dbda42b639095dc9ce 256 SMART SM00563 72 183 4.0E-28 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS23245 52075cf7beb4c6dbda42b639095dc9ce 256 Gene3D G3DSA:3.40.1130.10 69 203 6.8E-8 T 13-09-2016 THL1_RS23245 52075cf7beb4c6dbda42b639095dc9ce 256 SUPERFAMILY SSF69593 38 184 2.35E-23 T 13-09-2016 THL1_RS23245 52075cf7beb4c6dbda42b639095dc9ce 256 Pfam PF01553 Acyltransferase 66 180 2.9E-19 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS23245 52075cf7beb4c6dbda42b639095dc9ce 256 PANTHER PTHR10434:SF8 208 245 4.1E-66 T 13-09-2016 THL1_RS23245 52075cf7beb4c6dbda42b639095dc9ce 256 PANTHER PTHR10434:SF8 10 191 4.1E-66 T 13-09-2016 THL1_RS08665 8b7c6cd4b85ac229c9d3b46ae6a521d8 443 Gene3D G3DSA:3.40.50.300 2 216 8.3E-75 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08665 8b7c6cd4b85ac229c9d3b46ae6a521d8 443 Gene3D G3DSA:3.40.50.300 217 373 3.3E-48 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08665 8b7c6cd4b85ac229c9d3b46ae6a521d8 443 SUPERFAMILY SSF52540 72 359 5.23E-70 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08665 8b7c6cd4b85ac229c9d3b46ae6a521d8 443 SMART SM00490 257 338 6.5E-32 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS08665 8b7c6cd4b85ac229c9d3b46ae6a521d8 443 Pfam PF00271 Helicase conserved C-terminal domain 239 338 3.1E-27 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS08665 8b7c6cd4b85ac229c9d3b46ae6a521d8 443 PANTHER PTHR24031 2 368 8.2E-153 T 13-09-2016 THL1_RS08665 8b7c6cd4b85ac229c9d3b46ae6a521d8 443 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 150 158 - T 13-09-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site THL1_RS08665 8b7c6cd4b85ac229c9d3b46ae6a521d8 443 SMART SM00487 19 221 2.0E-53 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS08665 8b7c6cd4b85ac229c9d3b46ae6a521d8 443 Pfam PF00270 DEAD/DEAH box helicase 24 187 7.5E-46 T 13-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THL1_RS26585 b8027ca5978840082a1256614f1942ab 336 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 5 196 3.1E-60 T 13-09-2016 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 THL1_RS26585 b8027ca5978840082a1256614f1942ab 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 28 55 4.9E-75 T 13-09-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 THL1_RS26585 b8027ca5978840082a1256614f1942ab 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 208 235 4.9E-75 T 13-09-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 THL1_RS26585 b8027ca5978840082a1256614f1942ab 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 65 91 4.9E-75 T 13-09-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 THL1_RS26585 b8027ca5978840082a1256614f1942ab 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 310 335 4.9E-75 T 13-09-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 THL1_RS26585 b8027ca5978840082a1256614f1942ab 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 151 174 4.9E-75 T 13-09-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 THL1_RS26585 b8027ca5978840082a1256614f1942ab 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 182 205 4.9E-75 T 13-09-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 THL1_RS26585 b8027ca5978840082a1256614f1942ab 336 SUPERFAMILY SSF56655 2 334 9.16E-117 T 13-09-2016 THL1_RS26585 b8027ca5978840082a1256614f1942ab 336 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 4 336 47.341 T 13-09-2016 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0042132|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: REACT_474|UniPathway: UPA00138 THL1_RS26585 b8027ca5978840082a1256614f1942ab 336 PIRSF PIRSF500210 1 336 1.7E-128 T 13-09-2016 IPR028343 Fructose-1,6-bisphosphatase KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|UniPathway: UPA00138 THL1_RS26585 b8027ca5978840082a1256614f1942ab 336 Gene3D G3DSA:3.40.190.80 199 335 1.4E-57 T 13-09-2016 THL1_RS26585 b8027ca5978840082a1256614f1942ab 336 PIRSF PIRSF000904 1 336 6.7E-127 T 13-09-2016 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0042132|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: REACT_474|UniPathway: UPA00138 THL1_RS26585 b8027ca5978840082a1256614f1942ab 336 Gene3D G3DSA:3.30.540.10 4 198 1.2E-74 T 13-09-2016 THL1_RS26585 b8027ca5978840082a1256614f1942ab 336 PANTHER PTHR11556 4 336 1.4E-154 T 13-09-2016 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0042132|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: REACT_474|UniPathway: UPA00138 THL1_RS09215 0e067c81fa9b0e0976821dd13ff5820d 302 PANTHER PTHR12715:SF17 5 281 4.5E-46 T 13-09-2016 THL1_RS09215 0e067c81fa9b0e0976821dd13ff5820d 302 SUPERFAMILY SSF103481 41 139 6.02E-12 T 13-09-2016 THL1_RS09215 0e067c81fa9b0e0976821dd13ff5820d 302 SUPERFAMILY SSF103481 190 291 1.57E-12 T 13-09-2016 THL1_RS09215 0e067c81fa9b0e0976821dd13ff5820d 302 PANTHER PTHR12715 5 281 4.5E-46 T 13-09-2016 THL1_RS09215 0e067c81fa9b0e0976821dd13ff5820d 302 Pfam PF00892 EamA-like transporter family 10 136 6.3E-15 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS09215 0e067c81fa9b0e0976821dd13ff5820d 302 Pfam PF00892 EamA-like transporter family 148 289 2.1E-13 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS20060 6f70bfd4cc8723cc4067cfd8cfb0a6fb 429 SUPERFAMILY SSF55874 267 407 1.7E-27 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS20060 6f70bfd4cc8723cc4067cfd8cfb0a6fb 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 339 353 6.0E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS20060 6f70bfd4cc8723cc4067cfd8cfb0a6fb 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 389 6.0E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS20060 6f70bfd4cc8723cc4067cfd8cfb0a6fb 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 367 6.0E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS20060 6f70bfd4cc8723cc4067cfd8cfb0a6fb 429 SMART SM00387 307 411 2.4E-24 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS20060 6f70bfd4cc8723cc4067cfd8cfb0a6fb 429 SMART SM00388 199 265 2.6E-10 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS20060 6f70bfd4cc8723cc4067cfd8cfb0a6fb 429 Pfam PF00512 His Kinase A (phospho-acceptor) domain 203 261 4.4E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS20060 6f70bfd4cc8723cc4067cfd8cfb0a6fb 429 SUPERFAMILY SSF47384 182 263 3.53E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS20060 6f70bfd4cc8723cc4067cfd8cfb0a6fb 429 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 315 408 8.2E-16 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS20060 6f70bfd4cc8723cc4067cfd8cfb0a6fb 429 Gene3D G3DSA:3.30.565.10 271 407 6.8E-28 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS20060 6f70bfd4cc8723cc4067cfd8cfb0a6fb 429 PANTHER PTHR24423 1 8 1.7E-44 T 13-09-2016 THL1_RS20060 6f70bfd4cc8723cc4067cfd8cfb0a6fb 429 PANTHER PTHR24423 139 407 1.7E-44 T 13-09-2016 THL1_RS20060 6f70bfd4cc8723cc4067cfd8cfb0a6fb 429 Gene3D G3DSA:1.10.287.130 193 261 9.3E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS02280 523e90cf31b0daf74c1ea35938a18062 301 Pfam PF03466 LysR substrate binding domain 96 296 6.2E-31 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS02280 523e90cf31b0daf74c1ea35938a18062 301 SUPERFAMILY SSF46785 8 93 4.39E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02280 523e90cf31b0daf74c1ea35938a18062 301 Gene3D G3DSA:1.10.10.10 7 86 1.3E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02280 523e90cf31b0daf74c1ea35938a18062 301 PANTHER PTHR30126:SF16 8 295 3.0E-94 T 13-09-2016 THL1_RS02280 523e90cf31b0daf74c1ea35938a18062 301 PANTHER PTHR30126 8 295 3.0E-94 T 13-09-2016 THL1_RS02280 523e90cf31b0daf74c1ea35938a18062 301 Gene3D G3DSA:3.40.190.10 96 203 4.9E-16 T 13-09-2016 THL1_RS02280 523e90cf31b0daf74c1ea35938a18062 301 SUPERFAMILY SSF53850 98 298 1.99E-32 T 13-09-2016 THL1_RS02280 523e90cf31b0daf74c1ea35938a18062 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 69 8.4E-17 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS04565 329159d06cdd5db7c4e6810305f683d9 313 Pfam PF00850 Histone deacetylase domain 24 284 5.2E-47 T 13-09-2016 IPR023801 Histone deacetylase domain THL1_RS04565 329159d06cdd5db7c4e6810305f683d9 313 Gene3D G3DSA:3.40.800.20 4 284 7.4E-65 T 13-09-2016 IPR023801 Histone deacetylase domain THL1_RS04565 329159d06cdd5db7c4e6810305f683d9 313 SUPERFAMILY SSF52768 4 288 2.3E-79 T 13-09-2016 THL1_RS04565 329159d06cdd5db7c4e6810305f683d9 313 PANTHER PTHR10625:SF131 1 286 3.4E-121 T 13-09-2016 THL1_RS04565 329159d06cdd5db7c4e6810305f683d9 313 PRINTS PR01270 Histone deacetylase superfamily signature 117 140 5.2E-14 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS04565 329159d06cdd5db7c4e6810305f683d9 313 PRINTS PR01270 Histone deacetylase superfamily signature 225 235 5.2E-14 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS04565 329159d06cdd5db7c4e6810305f683d9 313 PRINTS PR01270 Histone deacetylase superfamily signature 151 166 5.2E-14 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS04565 329159d06cdd5db7c4e6810305f683d9 313 PANTHER PTHR10625 1 286 3.4E-121 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS15815 b37f0aeff39c8d1183691fbc2115bfb3 296 Gene3D G3DSA:1.10.10.60 190 240 1.3E-7 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15815 b37f0aeff39c8d1183691fbc2115bfb3 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 259 274 2.4E-7 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS15815 b37f0aeff39c8d1183691fbc2115bfb3 296 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 274 290 2.4E-7 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS15815 b37f0aeff39c8d1183691fbc2115bfb3 296 SMART SM00342 205 290 1.4E-24 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS15815 b37f0aeff39c8d1183691fbc2115bfb3 296 SUPERFAMILY SSF46689 241 292 6.72E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15815 b37f0aeff39c8d1183691fbc2115bfb3 296 Gene3D G3DSA:1.10.10.60 241 292 2.3E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15815 b37f0aeff39c8d1183691fbc2115bfb3 296 Pfam PF12833 Helix-turn-helix domain 214 291 3.5E-22 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS15815 b37f0aeff39c8d1183691fbc2115bfb3 296 PANTHER PTHR11019:SF50 45 291 2.2E-34 T 13-09-2016 THL1_RS15815 b37f0aeff39c8d1183691fbc2115bfb3 296 Pfam PF14525 AraC-binding-like domain 4 172 1.7E-24 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS15815 b37f0aeff39c8d1183691fbc2115bfb3 296 PANTHER PTHR11019 45 291 2.2E-34 T 13-09-2016 THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 Gene3D G3DSA:1.10.8.60 319 392 4.9E-22 T 13-09-2016 THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 SUPERFAMILY SSF52172 3 188 8.13E-11 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 PANTHER PTHR32071:SF36 1 490 2.0E-270 T 13-09-2016 THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 SMART SM00382 166 310 2.1E-10 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 Pfam PF02954 Bacterial regulatory protein, Fis family 439 478 1.5E-11 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 SUPERFAMILY SSF52540 146 387 2.8E-71 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 Pfam PF06490 Flagellar regulatory protein FleQ 6 123 5.2E-30 T 13-09-2016 IPR010518 Flagellar regulatory FleQ THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 SUPERFAMILY SSF46689 429 481 2.37E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 Pfam PF00158 Sigma-54 interaction domain 146 312 5.1E-76 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 Gene3D G3DSA:1.10.10.60 426 480 3.0E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 Gene3D G3DSA:3.40.50.2300 3 121 4.1E-4 T 13-09-2016 THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 358 367 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 170 183 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 232 247 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 Gene3D G3DSA:3.40.50.300 143 318 2.9E-64 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 444 461 4.2E-8 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 461 481 4.2E-8 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS19630 a6cf46eb7412a14149c56847598dde65 490 PANTHER PTHR32071 1 490 2.0E-270 T 13-09-2016 THL1_RS21510 c6e85c82fddc72b8b69074c022a8af97 265 PANTHER PTHR24220 5 216 2.2E-83 T 13-09-2016 THL1_RS21510 c6e85c82fddc72b8b69074c022a8af97 265 Gene3D G3DSA:3.40.50.300 2 216 5.0E-64 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21510 c6e85c82fddc72b8b69074c022a8af97 265 SMART SM00382 28 218 1.6E-13 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS21510 c6e85c82fddc72b8b69074c022a8af97 265 SUPERFAMILY SSF52540 3 216 1.86E-61 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21510 c6e85c82fddc72b8b69074c022a8af97 265 Pfam PF00005 ABC transporter 19 168 1.1E-32 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS27500 9e247b5ad2ef8657eeadcbc55476362e 276 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 274 1.7E-93 T 13-09-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS27500 9e247b5ad2ef8657eeadcbc55476362e 276 Gene3D G3DSA:3.10.310.10 3 122 1.2E-49 T 13-09-2016 THL1_RS27500 9e247b5ad2ef8657eeadcbc55476362e 276 Gene3D G3DSA:3.10.310.10 123 264 6.8E-55 T 13-09-2016 THL1_RS27500 9e247b5ad2ef8657eeadcbc55476362e 276 PANTHER PTHR31689:SF0 1 276 1.3E-139 T 13-09-2016 THL1_RS27500 9e247b5ad2ef8657eeadcbc55476362e 276 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 276 40.828 T 13-09-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS27500 9e247b5ad2ef8657eeadcbc55476362e 276 PANTHER PTHR31689 1 276 1.3E-139 T 13-09-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS27500 9e247b5ad2ef8657eeadcbc55476362e 276 SUPERFAMILY SSF54506 3 276 4.43E-54 T 13-09-2016 THL1_RS27500 9e247b5ad2ef8657eeadcbc55476362e 276 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 66 80 - T 13-09-2016 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS27500 9e247b5ad2ef8657eeadcbc55476362e 276 Pfam PF01678 Diaminopimelate epimerase 154 269 1.8E-33 T 13-09-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS27500 9e247b5ad2ef8657eeadcbc55476362e 276 Pfam PF01678 Diaminopimelate epimerase 5 126 1.6E-32 T 13-09-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS11970 460277a33ff3990686d4225c43c92b7a 424 SUPERFAMILY SSF55874 280 420 2.36E-28 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS11970 460277a33ff3990686d4225c43c92b7a 424 SMART SM00304 155 209 2.1E-6 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS11970 460277a33ff3990686d4225c43c92b7a 424 SUPERFAMILY SSF47384 193 275 5.1E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS11970 460277a33ff3990686d4225c43c92b7a 424 Gene3D G3DSA:1.10.287.130 203 272 1.1E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS11970 460277a33ff3990686d4225c43c92b7a 424 SMART SM00388 210 276 1.6E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS11970 460277a33ff3990686d4225c43c92b7a 424 Pfam PF00512 His Kinase A (phospho-acceptor) domain 212 275 1.2E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS11970 460277a33ff3990686d4225c43c92b7a 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 380 4.2E-8 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS11970 460277a33ff3990686d4225c43c92b7a 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 366 4.2E-8 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS11970 460277a33ff3990686d4225c43c92b7a 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 402 4.2E-8 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS11970 460277a33ff3990686d4225c43c92b7a 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 421 4.2E-8 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS11970 460277a33ff3990686d4225c43c92b7a 424 SMART SM00387 320 424 1.9E-27 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS11970 460277a33ff3990686d4225c43c92b7a 424 PANTHER PTHR24423 149 420 5.1E-50 T 13-09-2016 THL1_RS11970 460277a33ff3990686d4225c43c92b7a 424 PANTHER PTHR24423 1 7 5.1E-50 T 13-09-2016 THL1_RS11970 460277a33ff3990686d4225c43c92b7a 424 Gene3D G3DSA:3.30.565.10 283 420 4.3E-30 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS11970 460277a33ff3990686d4225c43c92b7a 424 Pfam PF00672 HAMP domain 136 206 1.3E-11 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS11970 460277a33ff3990686d4225c43c92b7a 424 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 323 420 3.2E-17 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS12350 b6b212d31a9b886f98139a5ecba15571 372 PANTHER PTHR11933:SF10 1 362 4.5E-206 T 13-09-2016 THL1_RS12350 b6b212d31a9b886f98139a5ecba15571 372 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 7 360 40.147 T 13-09-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 THL1_RS12350 b6b212d31a9b886f98139a5ecba15571 372 Gene3D G3DSA:2.40.30.10 282 364 2.1E-31 T 13-09-2016 THL1_RS12350 b6b212d31a9b886f98139a5ecba15571 372 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 8 359 1.8E-139 T 13-09-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 THL1_RS12350 b6b212d31a9b886f98139a5ecba15571 372 Gene3D G3DSA:2.30.30.280 213 281 2.7E-32 T 13-09-2016 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 THL1_RS12350 b6b212d31a9b886f98139a5ecba15571 372 SUPERFAMILY SSF52402 6 244 4.41E-56 T 13-09-2016 THL1_RS12350 b6b212d31a9b886f98139a5ecba15571 372 PANTHER PTHR11933 1 362 4.5E-206 T 13-09-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 THL1_RS12350 b6b212d31a9b886f98139a5ecba15571 372 Pfam PF03054 tRNA methyl transferase 8 359 2.9E-135 T 13-09-2016 THL1_RS12350 b6b212d31a9b886f98139a5ecba15571 372 Gene3D G3DSA:3.40.50.620 5 212 9.2E-97 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS18405 748906f8233450187c9d6390820a0248 661 SMART SM00878 338 444 6.4E-50 T 13-09-2016 IPR005482 Biotin carboxylase, C-terminal THL1_RS18405 748906f8233450187c9d6390820a0248 661 PANTHER PTHR18866 1 660 0.0 T 13-09-2016 THL1_RS18405 748906f8233450187c9d6390820a0248 661 SUPERFAMILY SSF52440 3 115 7.19E-50 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS18405 748906f8233450187c9d6390820a0248 661 Gene3D G3DSA:3.30.1490.20 132 203 3.5E-26 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS18405 748906f8233450187c9d6390820a0248 661 Gene3D G3DSA:3.40.50.20 4 131 9.7E-52 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS18405 748906f8233450187c9d6390820a0248 661 Gene3D G3DSA:2.40.50.100 588 658 7.1E-24 T 13-09-2016 THL1_RS18405 748906f8233450187c9d6390820a0248 661 Pfam PF02785 Biotin carboxylase C-terminal domain 338 444 1.8E-33 T 13-09-2016 IPR005482 Biotin carboxylase, C-terminal THL1_RS18405 748906f8233450187c9d6390820a0248 661 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 118 324 7.4E-74 T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS18405 748906f8233450187c9d6390820a0248 661 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 155 169 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS18405 748906f8233450187c9d6390820a0248 661 SUPERFAMILY SSF51246 333 446 5.13E-36 T 13-09-2016 IPR011054 Rudiment single hybrid motif THL1_RS18405 748906f8233450187c9d6390820a0248 661 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 614 631 - T 13-09-2016 IPR001882 Biotin-binding site THL1_RS18405 748906f8233450187c9d6390820a0248 661 Pfam PF00364 Biotin-requiring enzyme 591 656 3.3E-16 T 13-09-2016 IPR000089 Biotin/lipoyl attachment THL1_RS18405 748906f8233450187c9d6390820a0248 661 SUPERFAMILY SSF51230 588 658 3.8E-21 T 13-09-2016 IPR011053 Single hybrid motif THL1_RS18405 748906f8233450187c9d6390820a0248 661 Pfam PF00289 Biotin carboxylase, N-terminal domain 4 112 3.2E-45 T 13-09-2016 IPR005481 Biotin carboxylase-like, N-terminal domain THL1_RS18405 748906f8233450187c9d6390820a0248 661 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS18405 748906f8233450187c9d6390820a0248 661 PANTHER PTHR18866:SF102 1 660 0.0 T 13-09-2016 THL1_RS18405 748906f8233450187c9d6390820a0248 661 SUPERFAMILY SSF56059 85 349 3.18E-67 T 13-09-2016 THL1_RS18405 748906f8233450187c9d6390820a0248 661 Gene3D G3DSA:3.30.470.20 207 447 4.4E-101 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS06445 665e3307fcbb584f8a90747245fa50ba 625 Pfam PF00672 HAMP domain 275 344 4.9E-16 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS06445 665e3307fcbb584f8a90747245fa50ba 625 Pfam PF02743 Cache domain 36 257 1.2E-33 T 13-09-2016 IPR033479 Double Cache domain 1 THL1_RS06445 665e3307fcbb584f8a90747245fa50ba 625 SMART SM00304 294 348 3.3E-15 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS06445 665e3307fcbb584f8a90747245fa50ba 625 SMART SM00304 383 443 8.5 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS06445 665e3307fcbb584f8a90747245fa50ba 625 PANTHER PTHR32089 1 625 0.0 T 13-09-2016 THL1_RS06445 665e3307fcbb584f8a90747245fa50ba 625 SMART SM00283 363 624 1.4E-94 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS06445 665e3307fcbb584f8a90747245fa50ba 625 SUPERFAMILY SSF103190 86 180 7.06E-13 T 13-09-2016 IPR029151 Periplasmic sensor domain-like THL1_RS06445 665e3307fcbb584f8a90747245fa50ba 625 Gene3D G3DSA:3.30.450.20 70 155 1.9E-27 T 13-09-2016 THL1_RS06445 665e3307fcbb584f8a90747245fa50ba 625 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 417 623 1.6E-47 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS06445 665e3307fcbb584f8a90747245fa50ba 625 Gene3D G3DSA:3.30.450.20 156 272 3.3E-30 T 13-09-2016 THL1_RS06445 665e3307fcbb584f8a90747245fa50ba 625 PANTHER PTHR32089:SF39 1 625 0.0 T 13-09-2016 THL1_RS06445 665e3307fcbb584f8a90747245fa50ba 625 Gene3D G3DSA:1.10.287.950 377 594 3.2E-57 T 13-09-2016 THL1_RS06445 665e3307fcbb584f8a90747245fa50ba 625 SUPERFAMILY SSF58104 316 625 3.4E-77 T 13-09-2016 THL1_RS24315 b1309acffc2cd5ddbb19dadc5d0b4c16 126 Gene3D G3DSA:2.40.40.20 1 124 4.6E-50 T 13-09-2016 THL1_RS24315 b1309acffc2cd5ddbb19dadc5d0b4c16 126 Pfam PF02261 Aspartate decarboxylase 1 113 2.8E-45 T 13-09-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 THL1_RS24315 b1309acffc2cd5ddbb19dadc5d0b4c16 126 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 123 2.0E-63 T 13-09-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 THL1_RS24315 b1309acffc2cd5ddbb19dadc5d0b4c16 126 SUPERFAMILY SSF50692 1 122 2.49E-46 T 13-09-2016 IPR009010 Aspartate decarboxylase-like domain THL1_RS24315 b1309acffc2cd5ddbb19dadc5d0b4c16 126 PANTHER PTHR21012:SF0 2 126 7.6E-64 T 13-09-2016 THL1_RS24315 b1309acffc2cd5ddbb19dadc5d0b4c16 126 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 126 65.862 T 13-09-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 THL1_RS24315 b1309acffc2cd5ddbb19dadc5d0b4c16 126 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 126 1.6E-46 T 13-09-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 THL1_RS24315 b1309acffc2cd5ddbb19dadc5d0b4c16 126 PIRSF PIRSF006246 1 125 8.2E-50 T 13-09-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 THL1_RS24315 b1309acffc2cd5ddbb19dadc5d0b4c16 126 PANTHER PTHR21012 2 126 7.6E-64 T 13-09-2016 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155|UniPathway: UPA00028 THL1_RS25265 bae4ed1e571242f82db57fcc25b9490f 468 Gene3D G3DSA:3.40.640.10 134 313 5.4E-31 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS25265 bae4ed1e571242f82db57fcc25b9490f 468 PANTHER PTHR32328 5 457 1.1E-208 T 13-09-2016 THL1_RS25265 bae4ed1e571242f82db57fcc25b9490f 468 Pfam PF03841 L-seryl-tRNA selenium transferase 79 450 2.2E-167 T 13-09-2016 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1|UniPathway: UPA00906 THL1_RS25265 bae4ed1e571242f82db57fcc25b9490f 468 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 4 459 2.8E-179 T 13-09-2016 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1|UniPathway: UPA00906 THL1_RS25265 bae4ed1e571242f82db57fcc25b9490f 468 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 466 239.831 T 13-09-2016 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1|UniPathway: UPA00906 THL1_RS25265 bae4ed1e571242f82db57fcc25b9490f 468 PANTHER PTHR32328:SF0 5 457 1.1E-208 T 13-09-2016 THL1_RS25265 bae4ed1e571242f82db57fcc25b9490f 468 SUPERFAMILY SSF53383 73 380 8.79E-45 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS25265 bae4ed1e571242f82db57fcc25b9490f 468 Pfam PF12390 Selenocysteine synthase N terminal 5 42 1.1E-8 T 13-09-2016 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1|UniPathway: UPA00906 THL1_RS18180 ac186f8827cf5c934f81350b65f96c90 385 PRINTS PR00143 Citrate synthase signature 185 200 2.3E-34 T 13-09-2016 IPR002020 Citrate synthase GO:0046912 THL1_RS18180 ac186f8827cf5c934f81350b65f96c90 385 PRINTS PR00143 Citrate synthase signature 260 280 2.3E-34 T 13-09-2016 IPR002020 Citrate synthase GO:0046912 THL1_RS18180 ac186f8827cf5c934f81350b65f96c90 385 PRINTS PR00143 Citrate synthase signature 337 351 2.3E-34 T 13-09-2016 IPR002020 Citrate synthase GO:0046912 THL1_RS18180 ac186f8827cf5c934f81350b65f96c90 385 PRINTS PR00143 Citrate synthase signature 317 333 2.3E-34 T 13-09-2016 IPR002020 Citrate synthase GO:0046912 THL1_RS18180 ac186f8827cf5c934f81350b65f96c90 385 PRINTS PR00143 Citrate synthase signature 207 235 2.3E-34 T 13-09-2016 IPR002020 Citrate synthase GO:0046912 THL1_RS18180 ac186f8827cf5c934f81350b65f96c90 385 PIRSF PIRSF001369 10 385 1.5E-106 T 13-09-2016 IPR024176 Citrate synthase, bacterial-type UniPathway: UPA00223 THL1_RS18180 ac186f8827cf5c934f81350b65f96c90 385 PANTHER PTHR11739:SF4 18 384 9.4E-149 T 13-09-2016 THL1_RS18180 ac186f8827cf5c934f81350b65f96c90 385 PANTHER PTHR11739 18 384 9.4E-149 T 13-09-2016 IPR002020 Citrate synthase GO:0046912 THL1_RS18180 ac186f8827cf5c934f81350b65f96c90 385 Gene3D G3DSA:1.10.230.10 246 331 5.2E-29 T 13-09-2016 IPR016143 Citrate synthase-like, small alpha subdomain THL1_RS18180 ac186f8827cf5c934f81350b65f96c90 385 Gene3D G3DSA:1.10.580.10 23 245 2.4E-73 T 13-09-2016 IPR016142 Citrate synthase-like, large alpha subdomain UniPathway: UPA00223 THL1_RS18180 ac186f8827cf5c934f81350b65f96c90 385 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 17 384 2.2E-152 T 13-09-2016 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 THL1_RS18180 ac186f8827cf5c934f81350b65f96c90 385 SUPERFAMILY SSF48256 18 384 4.71E-121 T 13-09-2016 IPR002020 Citrate synthase GO:0046912 THL1_RS18180 ac186f8827cf5c934f81350b65f96c90 385 ProSitePatterns PS00480 Citrate synthase signature. 267 279 - T 13-09-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 UniPathway: UPA00223 THL1_RS18180 ac186f8827cf5c934f81350b65f96c90 385 Pfam PF00285 Citrate synthase, C-terminal domain 18 366 5.4E-111 T 13-09-2016 IPR002020 Citrate synthase GO:0046912 THL1_RS24280 952968ff1e5d3da97077adcd20b5a545 295 PANTHER PTHR11451:SF35 2 221 1.4E-113 T 13-09-2016 THL1_RS24280 952968ff1e5d3da97077adcd20b5a545 295 PANTHER PTHR11451 244 260 1.4E-113 T 13-09-2016 THL1_RS24280 952968ff1e5d3da97077adcd20b5a545 295 Gene3D G3DSA:3.90.800.10 72 170 1.9E-21 T 13-09-2016 THL1_RS24280 952968ff1e5d3da97077adcd20b5a545 295 PRINTS PR00987 Glutamyl-tRNA synthetase signature 9 21 6.8E-13 T 13-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 THL1_RS24280 952968ff1e5d3da97077adcd20b5a545 295 PRINTS PR00987 Glutamyl-tRNA synthetase signature 23 34 6.8E-13 T 13-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 THL1_RS24280 952968ff1e5d3da97077adcd20b5a545 295 PRINTS PR00987 Glutamyl-tRNA synthetase signature 170 180 6.8E-13 T 13-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 THL1_RS24280 952968ff1e5d3da97077adcd20b5a545 295 PRINTS PR00987 Glutamyl-tRNA synthetase signature 186 194 6.8E-13 T 13-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 THL1_RS24280 952968ff1e5d3da97077adcd20b5a545 295 PRINTS PR00987 Glutamyl-tRNA synthetase signature 38 51 6.8E-13 T 13-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 THL1_RS24280 952968ff1e5d3da97077adcd20b5a545 295 PANTHER PTHR11451 2 221 1.4E-113 T 13-09-2016 THL1_RS24280 952968ff1e5d3da97077adcd20b5a545 295 PANTHER PTHR11451:SF35 244 260 1.4E-113 T 13-09-2016 THL1_RS24280 952968ff1e5d3da97077adcd20b5a545 295 SUPERFAMILY SSF52374 6 286 2.52E-86 T 13-09-2016 THL1_RS24280 952968ff1e5d3da97077adcd20b5a545 295 Gene3D G3DSA:3.40.50.620 6 71 4.7E-42 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS24280 952968ff1e5d3da97077adcd20b5a545 295 Gene3D G3DSA:3.40.50.620 172 221 4.7E-42 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS24280 952968ff1e5d3da97077adcd20b5a545 295 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 6 290 43.702 T 13-09-2016 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 THL1_RS24280 952968ff1e5d3da97077adcd20b5a545 295 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 6 271 4.1E-112 T 13-09-2016 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0006400|GO:0016876 THL1_RS24280 952968ff1e5d3da97077adcd20b5a545 295 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 9 231 7.4E-44 T 13-09-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 THL1_RS25780 c1d63a12d48455fa02c76ebf2332cb7a 464 Pfam PF03796 DnaB-like helicase C terminal domain 197 453 3.9E-113 T 13-09-2016 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 THL1_RS25780 c1d63a12d48455fa02c76ebf2332cb7a 464 SUPERFAMILY SSF48024 18 129 3.01E-40 T 13-09-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 THL1_RS25780 c1d63a12d48455fa02c76ebf2332cb7a 464 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 20 455 6.5E-173 T 13-09-2016 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 THL1_RS25780 c1d63a12d48455fa02c76ebf2332cb7a 464 Pfam PF00772 DnaB-like helicase N terminal domain 20 121 7.9E-37 T 13-09-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 THL1_RS25780 c1d63a12d48455fa02c76ebf2332cb7a 464 Gene3D G3DSA:3.40.50.300 182 455 2.4E-106 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25780 c1d63a12d48455fa02c76ebf2332cb7a 464 Gene3D G3DSA:1.10.860.10 20 122 6.1E-40 T 13-09-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal THL1_RS25780 c1d63a12d48455fa02c76ebf2332cb7a 464 PANTHER PTHR30153 4 463 1.5E-214 T 13-09-2016 THL1_RS25780 c1d63a12d48455fa02c76ebf2332cb7a 464 SUPERFAMILY SSF52540 195 446 1.5E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11950 b644e68030df5f820da98d9eaf30b944 231 Pfam PF09335 SNARE associated Golgi protein 64 180 2.7E-23 T 13-09-2016 IPR032816 SNARE associated Golgi protein THL1_RS11950 b644e68030df5f820da98d9eaf30b944 231 PANTHER PTHR12677 1 182 1.2E-18 T 13-09-2016 IPR015414 Transmembrane protein TMEM64/TMEM41 GO:0016021 THL1_RS13745 d3adae99fbad9dc530e57d63d7d6d659 440 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 13 432 1.1E-89 T 13-09-2016 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit THL1_RS13745 d3adae99fbad9dc530e57d63d7d6d659 440 PANTHER PTHR33362 11 437 2.6E-128 T 13-09-2016 THL1_RS13745 d3adae99fbad9dc530e57d63d7d6d659 440 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 23 437 2.5E-90 T 13-09-2016 IPR004681 TRAP transporter permease protein GO:0016021 THL1_RS13745 d3adae99fbad9dc530e57d63d7d6d659 440 PANTHER PTHR33362:SF5 11 437 2.6E-128 T 13-09-2016 THL1_RS13745 d3adae99fbad9dc530e57d63d7d6d659 440 PIRSF PIRSF006066 6 440 6.8E-85 T 13-09-2016 IPR004681 TRAP transporter permease protein GO:0016021 THL1_RS19935 29166afcf6608f2b9ce39f75e022baac 261 PANTHER PTHR20854 1 259 4.5E-89 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS19935 29166afcf6608f2b9ce39f75e022baac 261 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 11 258 9.9E-92 T 13-09-2016 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15|UniPathway: UPA00031 THL1_RS19935 29166afcf6608f2b9ce39f75e022baac 261 Pfam PF00459 Inositol monophosphatase family 9 259 4.2E-45 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS19935 29166afcf6608f2b9ce39f75e022baac 261 Gene3D G3DSA:3.40.190.80 156 259 2.6E-22 T 13-09-2016 THL1_RS19935 29166afcf6608f2b9ce39f75e022baac 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 86 102 6.9E-23 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS19935 29166afcf6608f2b9ce39f75e022baac 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 209 233 6.9E-23 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS19935 29166afcf6608f2b9ce39f75e022baac 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 66 82 6.9E-23 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS19935 29166afcf6608f2b9ce39f75e022baac 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 44 64 6.9E-23 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS19935 29166afcf6608f2b9ce39f75e022baac 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 134 157 6.9E-23 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS19935 29166afcf6608f2b9ce39f75e022baac 261 PANTHER PTHR20854:SF38 1 259 4.5E-89 T 13-09-2016 THL1_RS19935 29166afcf6608f2b9ce39f75e022baac 261 Gene3D G3DSA:3.30.540.10 9 155 1.7E-38 T 13-09-2016 THL1_RS19935 29166afcf6608f2b9ce39f75e022baac 261 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 86 99 - T 13-09-2016 IPR020583 Inositol monophosphatase, metal-binding site THL1_RS19935 29166afcf6608f2b9ce39f75e022baac 261 SUPERFAMILY SSF56655 9 259 8.38E-69 T 13-09-2016 THL1_RS14745 a9ceff7185ebf6d23c5f148ce6103563 208 SUPERFAMILY SSF89562 11 171 2.09E-38 T 13-09-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein THL1_RS14745 a9ceff7185ebf6d23c5f148ce6103563 208 Pfam PF03737 Demethylmenaquinone methyltransferase 25 164 1.8E-31 T 13-09-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein THL1_RS14745 a9ceff7185ebf6d23c5f148ce6103563 208 PANTHER PTHR33254:SF5 36 207 3.1E-29 T 13-09-2016 THL1_RS14745 a9ceff7185ebf6d23c5f148ce6103563 208 Gene3D G3DSA:3.50.30.40 22 171 9.2E-41 T 13-09-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein THL1_RS14745 a9ceff7185ebf6d23c5f148ce6103563 208 PANTHER PTHR33254 36 207 3.1E-29 T 13-09-2016 THL1_RS13020 a89a23bfb206b57ef72a275f96e5f2b7 407 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 42 376 1.8E-66 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS13020 a89a23bfb206b57ef72a275f96e5f2b7 407 Gene3D G3DSA:3.40.50.1100 180 356 4.9E-17 T 13-09-2016 THL1_RS13020 a89a23bfb206b57ef72a275f96e5f2b7 407 Gene3D G3DSA:3.40.50.1100 73 179 6.8E-23 T 13-09-2016 THL1_RS13020 a89a23bfb206b57ef72a275f96e5f2b7 407 TIGRFAM TIGR01747 diampropi_NH3ly: diaminopropionate ammonia-lyase family 22 388 3.8E-83 T 13-09-2016 IPR010081 Diaminopropionate ammonia-lyase GO:0008838|GO:0030170 THL1_RS13020 a89a23bfb206b57ef72a275f96e5f2b7 407 PANTHER PTHR10314 114 388 5.1E-69 T 13-09-2016 THL1_RS13020 a89a23bfb206b57ef72a275f96e5f2b7 407 PANTHER PTHR10314 3 95 5.1E-69 T 13-09-2016 THL1_RS13020 a89a23bfb206b57ef72a275f96e5f2b7 407 SUPERFAMILY SSF53686 43 354 2.49E-61 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS13020 a89a23bfb206b57ef72a275f96e5f2b7 407 PANTHER PTHR10314:SF127 114 388 5.1E-69 T 13-09-2016 THL1_RS13020 a89a23bfb206b57ef72a275f96e5f2b7 407 PANTHER PTHR10314:SF127 3 95 5.1E-69 T 13-09-2016 THL1_RS18325 e31708210d9a8a7d23a30230488f4a35 404 Pfam PF03594 Benzoate membrane transport protein 19 394 7.2E-159 T 13-09-2016 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 THL1_RS18325 e31708210d9a8a7d23a30230488f4a35 404 TIGRFAM TIGR00843 benE: benzoate transporter 20 396 8.9E-134 T 13-09-2016 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 THL1_RS18325 e31708210d9a8a7d23a30230488f4a35 404 PANTHER PTHR30199 6 403 3.0E-166 T 13-09-2016 THL1_RS18325 e31708210d9a8a7d23a30230488f4a35 404 PANTHER PTHR30199:SF0 6 403 3.0E-166 T 13-09-2016 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 THL1_RS21065 a502c4d44b738d277bb1dec71a293107 195 Gene3D G3DSA:1.10.10.60 137 181 1.4E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21065 a502c4d44b738d277bb1dec71a293107 195 SUPERFAMILY SSF46689 137 188 1.29E-6 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21065 a502c4d44b738d277bb1dec71a293107 195 Pfam PF13384 Homeodomain-like domain 145 184 3.7E-8 T 13-09-2016 THL1_RS21065 a502c4d44b738d277bb1dec71a293107 195 SUPERFAMILY SSF53041 3 137 6.02E-33 T 13-09-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 THL1_RS21065 a502c4d44b738d277bb1dec71a293107 195 Gene3D G3DSA:3.40.50.1390 3 119 3.3E-30 T 13-09-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 THL1_RS21065 a502c4d44b738d277bb1dec71a293107 195 ProSitePatterns PS00398 Site-specific recombinases signature 2. 56 68 - T 13-09-2016 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 THL1_RS21065 a502c4d44b738d277bb1dec71a293107 195 Pfam PF00239 Resolvase, N terminal domain 3 137 9.4E-35 T 13-09-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 THL1_RS21065 a502c4d44b738d277bb1dec71a293107 195 PANTHER PTHR30461 3 179 1.6E-52 T 13-09-2016 THL1_RS21065 a502c4d44b738d277bb1dec71a293107 195 PANTHER PTHR30461:SF9 3 179 1.6E-52 T 13-09-2016 THL1_RS21065 a502c4d44b738d277bb1dec71a293107 195 SMART SM00857 2 137 1.1E-41 T 13-09-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 THL1_RS02805 29edc67f25d3c32d92e4b87f6e1f3aaf 233 SMART SM00895 82 214 1.2E-17 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS02805 29edc67f25d3c32d92e4b87f6e1f3aaf 233 SUPERFAMILY SSF48008 77 218 4.71E-21 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS02805 29edc67f25d3c32d92e4b87f6e1f3aaf 233 Pfam PF07729 FCD domain 82 213 3.1E-22 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS02805 29edc67f25d3c32d92e4b87f6e1f3aaf 233 SUPERFAMILY SSF46785 15 76 1.52E-13 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02805 29edc67f25d3c32d92e4b87f6e1f3aaf 233 Gene3D G3DSA:1.20.120.530 75 224 9.8E-29 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS02805 29edc67f25d3c32d92e4b87f6e1f3aaf 233 Gene3D G3DSA:1.10.10.10 15 74 2.7E-14 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02805 29edc67f25d3c32d92e4b87f6e1f3aaf 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 72 2.0E-13 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS02805 29edc67f25d3c32d92e4b87f6e1f3aaf 233 PANTHER PTHR11751 15 98 2.1E-19 T 13-09-2016 THL1_RS02805 29edc67f25d3c32d92e4b87f6e1f3aaf 233 SMART SM00345 14 72 1.2E-16 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS03780 a11b4be57724715394d165ffd1a06430 294 Gene3D G3DSA:3.40.50.720 3 229 1.5E-23 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS03780 a11b4be57724715394d165ffd1a06430 294 Pfam PF04321 RmlD substrate binding domain 3 290 4.1E-75 T 13-09-2016 IPR029903 RmlD-like substrate binding domain THL1_RS03780 a11b4be57724715394d165ffd1a06430 294 SUPERFAMILY SSF51735 3 291 5.87E-56 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS03780 a11b4be57724715394d165ffd1a06430 294 PANTHER PTHR10491 1 290 9.9E-54 T 13-09-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family THL1_RS03780 a11b4be57724715394d165ffd1a06430 294 PANTHER PTHR10491:SF4 1 290 9.9E-54 T 13-09-2016 THL1_RS26725 d64505f34abf721e9bd9a7b15c321e23 254 PANTHER PTHR30105 6 253 1.4E-81 T 13-09-2016 THL1_RS26725 d64505f34abf721e9bd9a7b15c321e23 254 Gene3D G3DSA:3.20.20.370 19 239 3.5E-86 T 13-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 THL1_RS26725 d64505f34abf721e9bd9a7b15c321e23 254 Pfam PF04748 Divergent polysaccharide deacetylase 29 235 2.6E-73 T 13-09-2016 IPR006837 Protein of unknown function DUF610, YibQ THL1_RS26725 d64505f34abf721e9bd9a7b15c321e23 254 SUPERFAMILY SSF88713 26 236 3.06E-68 T 13-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THL1_RS17140 2ba7dbb58d0d3c1e149cd9976d88bf9a 363 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 48 265 6.9E-16 T 13-09-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THL1_RS17140 2ba7dbb58d0d3c1e149cd9976d88bf9a 363 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 36 355 9.3E-69 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS17140 2ba7dbb58d0d3c1e149cd9976d88bf9a 363 Gene3D G3DSA:2.40.50.100 169 200 7.7E-12 T 13-09-2016 THL1_RS17140 2ba7dbb58d0d3c1e149cd9976d88bf9a 363 Gene3D G3DSA:2.40.50.100 66 94 7.7E-12 T 13-09-2016 THL1_RS17140 2ba7dbb58d0d3c1e149cd9976d88bf9a 363 SUPERFAMILY SSF111369 51 276 2.35E-24 T 13-09-2016 THL1_RS17140 2ba7dbb58d0d3c1e149cd9976d88bf9a 363 PANTHER PTHR30469:SF7 16 356 4.6E-84 T 13-09-2016 THL1_RS17140 2ba7dbb58d0d3c1e149cd9976d88bf9a 363 PANTHER PTHR30469 16 356 4.6E-84 T 13-09-2016 THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 Gene3D G3DSA:3.40.190.10 115 214 8.3E-15 T 13-09-2016 THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 Pfam PF00990 Diguanylate cyclase, GGDEF domain 808 965 7.9E-52 T 13-09-2016 IPR000160 GGDEF domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 255 1.4E-38 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SMART SM00091 683 749 8.5E-9 T 13-09-2016 IPR000014 PAS domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SMART SM00091 311 379 1.2 T 13-09-2016 IPR000014 PAS domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SMART SM00091 562 632 2.3E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SMART SM00091 437 504 0.052 T 13-09-2016 IPR000014 PAS domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SMART SM00062 37 257 1.0E-33 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 Pfam PF00563 EAL domain 986 1218 3.1E-72 T 13-09-2016 IPR001633 EAL domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SMART SM00052 979 1225 4.1E-118 T 13-09-2016 IPR001633 EAL domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 804 968 2.0E-44 T 13-09-2016 IPR000160 GGDEF domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 Gene3D G3DSA:3.30.70.270 809 977 2.2E-59 T 13-09-2016 THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SUPERFAMILY SSF55785 688 795 4.83E-31 T 13-09-2016 IPR000014 PAS domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SUPERFAMILY SSF141868 984 1232 1.03E-86 T 13-09-2016 IPR001633 EAL domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SUPERFAMILY SSF55785 297 423 3.06E-17 T 13-09-2016 IPR000014 PAS domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 Gene3D G3DSA:3.30.450.20 548 672 4.9E-22 T 13-09-2016 THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 Gene3D G3DSA:3.30.450.20 429 547 4.0E-22 T 13-09-2016 THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SUPERFAMILY SSF55073 813 970 1.49E-52 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 Gene3D G3DSA:3.30.450.20 294 428 6.4E-24 T 13-09-2016 THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 Gene3D G3DSA:3.40.190.10 35 114 4.2E-25 T 13-09-2016 THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 Gene3D G3DSA:3.40.190.10 217 256 4.2E-25 T 13-09-2016 THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SMART SM00267 797 969 2.5E-71 T 13-09-2016 IPR000160 GGDEF domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SMART SM00086 635 675 0.004 T 13-09-2016 IPR001610 PAC motif THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SMART SM00086 385 425 1.3E-5 T 13-09-2016 IPR001610 PAC motif THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SMART SM00086 510 550 0.87 T 13-09-2016 IPR001610 PAC motif THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SMART SM00086 755 797 1.7E-6 T 13-09-2016 IPR001610 PAC motif THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 Gene3D G3DSA:3.20.20.450 982 1229 2.6E-97 T 13-09-2016 IPR001633 EAL domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 PANTHER PTHR33121:SF13 924 1230 3.5E-89 T 13-09-2016 THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 687 804 2.6E-20 T 13-09-2016 IPR000014 PAS domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 559 682 1.9E-19 T 13-09-2016 IPR000014 PAS domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 435 556 1.4E-12 T 13-09-2016 IPR000014 PAS domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 307 432 5.6E-13 T 13-09-2016 IPR000014 PAS domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 PANTHER PTHR33121 924 1230 3.5E-89 T 13-09-2016 THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SUPERFAMILY SSF55785 547 673 4.67E-21 T 13-09-2016 IPR000014 PAS domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 Pfam PF13426 PAS domain 694 795 1.5E-17 T 13-09-2016 IPR000014 PAS domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 Pfam PF13426 PAS domain 572 674 1.2E-10 T 13-09-2016 IPR000014 PAS domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 Pfam PF13426 PAS domain 447 549 1.1E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 Gene3D G3DSA:3.30.450.20 673 791 1.6E-31 T 13-09-2016 THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SUPERFAMILY SSF53850 38 256 7.76E-51 T 13-09-2016 THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 Pfam PF08447 PAS fold 335 410 4.4E-10 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS02525 f35ce9fbf7cbcb3818e00ff594b042d0 1245 SUPERFAMILY SSF55785 422 548 1.03E-20 T 13-09-2016 IPR000014 PAS domain THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 PANTHER PTHR11817 1 483 1.5E-288 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 SUPERFAMILY SSF51621 169 346 3.49E-91 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 SUPERFAMILY SSF51621 2 77 3.49E-91 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 4 478 6.7E-157 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 Pfam PF00224 Pyruvate kinase, barrel domain 4 342 3.1E-121 T 13-09-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 Pfam PF02887 Pyruvate kinase, alpha/beta domain 361 476 3.1E-27 T 13-09-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 ProSitePatterns PS00110 Pyruvate kinase active site signature. 216 228 - T 13-09-2016 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 SUPERFAMILY SSF52935 327 479 5.63E-37 T 13-09-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 PRINTS PR01050 Pyruvate kinase family signature 273 297 4.6E-49 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 PRINTS PR01050 Pyruvate kinase family signature 298 316 4.6E-49 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 PRINTS PR01050 Pyruvate kinase family signature 248 272 4.6E-49 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 PRINTS PR01050 Pyruvate kinase family signature 188 202 4.6E-49 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 PRINTS PR01050 Pyruvate kinase family signature 221 247 4.6E-49 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 PRINTS PR01050 Pyruvate kinase family signature 61 77 4.6E-49 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 PRINTS PR01050 Pyruvate kinase family signature 317 333 4.6E-49 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 PANTHER PTHR11817:SF17 1 483 1.5E-288 T 13-09-2016 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 Gene3D G3DSA:3.20.20.60 170 329 4.5E-93 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 Gene3D G3DSA:3.20.20.60 4 74 4.5E-93 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 Gene3D G3DSA:2.40.33.10 75 169 1.0E-26 T 13-09-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 SUPERFAMILY SSF50800 72 165 3.84E-24 T 13-09-2016 IPR011037 Pyruvate kinase-like, insert domain THL1_RS23160 1ac8858162a4bffdb2d3f141501e9130 483 Gene3D G3DSA:3.40.1380.20 330 478 8.0E-38 T 13-09-2016 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 13-09-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 PANTHER PTHR11615:SF134 456 505 0.0 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 Gene3D G3DSA:3.10.20.30 3 84 1.6E-8 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS12275 717543b2504477df5103d03d92f39fec 902 PANTHER PTHR11615:SF134 731 894 0.0 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 PANTHER PTHR11615:SF134 3 315 0.0 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 150 160 - T 13-09-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 Gene3D G3DSA:2.40.40.20 814 881 4.0E-4 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 221 274 1.0E-11 T 13-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 88 126 2.4E-14 T 13-09-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 SUPERFAMILY SSF54862 81 213 6.7E-34 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 SMART SM00926 221 275 3.5E-11 T 13-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 650 4.1E-214 T 13-09-2016 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 Gene3D G3DSA:3.40.50.740 287 335 3.4E-37 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 Gene3D G3DSA:3.40.50.740 499 679 3.4E-37 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 Pfam PF00384 Molybdopterin oxidoreductase 359 632 4.0E-12 T 13-09-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 PANTHER PTHR11615 3 315 0.0 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 PANTHER PTHR11615 456 505 0.0 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 103 115 - T 13-09-2016 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 SUPERFAMILY SSF53706 219 683 4.26E-89 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 PANTHER PTHR11615 539 684 0.0 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 PANTHER PTHR11615 731 894 0.0 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 PANTHER PTHR11615 359 425 0.0 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 3 75 3.2E-10 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 SUPERFAMILY SSF54292 1 77 1.29E-18 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 Gene3D G3DSA:3.30.70.20 147 157 2.0E-5 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 Gene3D G3DSA:3.30.70.20 198 226 2.0E-5 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 SUPERFAMILY SSF50692 808 886 3.23E-7 T 13-09-2016 IPR009010 Aspartate decarboxylase-like domain THL1_RS12275 717543b2504477df5103d03d92f39fec 902 PANTHER PTHR11615:SF134 539 684 0.0 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 PANTHER PTHR11615:SF134 359 425 0.0 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 Gene3D G3DSA:2.20.25.90 227 275 1.1E-14 T 13-09-2016 THL1_RS12275 717543b2504477df5103d03d92f39fec 902 SMART SM00929 88 128 7.7E-19 T 13-09-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 THL1_RS00105 130f9b77ca6e64c07473e6193bdb9f3b 168 SUPERFAMILY SSF56420 2 165 6.02E-65 T 13-09-2016 IPR023635 Peptide deformylase THL1_RS00105 130f9b77ca6e64c07473e6193bdb9f3b 168 Gene3D G3DSA:3.90.45.10 5 165 5.8E-67 T 13-09-2016 IPR023635 Peptide deformylase THL1_RS00105 130f9b77ca6e64c07473e6193bdb9f3b 168 PANTHER PTHR10458:SF10 1 168 8.7E-103 T 13-09-2016 THL1_RS00105 130f9b77ca6e64c07473e6193bdb9f3b 168 Pfam PF01327 Polypeptide deformylase 4 153 1.2E-52 T 13-09-2016 IPR023635 Peptide deformylase THL1_RS00105 130f9b77ca6e64c07473e6193bdb9f3b 168 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 161 5.4E-56 T 13-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 THL1_RS00105 130f9b77ca6e64c07473e6193bdb9f3b 168 PRINTS PR01576 Peptide deformylase signature 33 62 7.8E-40 T 13-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 THL1_RS00105 130f9b77ca6e64c07473e6193bdb9f3b 168 PRINTS PR01576 Peptide deformylase signature 90 101 7.8E-40 T 13-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 THL1_RS00105 130f9b77ca6e64c07473e6193bdb9f3b 168 PRINTS PR01576 Peptide deformylase signature 121 150 7.8E-40 T 13-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 THL1_RS00105 130f9b77ca6e64c07473e6193bdb9f3b 168 PRINTS PR01576 Peptide deformylase signature 102 120 7.8E-40 T 13-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 THL1_RS00105 130f9b77ca6e64c07473e6193bdb9f3b 168 PIRSF PIRSF004749 1 168 1.0E-59 T 13-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 THL1_RS00105 130f9b77ca6e64c07473e6193bdb9f3b 168 Hamap MF_00163 Peptide deformylase [def]. 2 163 32.35 T 13-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 THL1_RS00105 130f9b77ca6e64c07473e6193bdb9f3b 168 PANTHER PTHR10458 1 168 8.7E-103 T 13-09-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 PANTHER PTHR32071 4 476 1.6E-173 T 13-09-2016 THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 SUPERFAMILY SSF52172 4 193 1.07E-42 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 SUPERFAMILY SSF46689 364 468 2.69E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 SUPERFAMILY SSF52540 143 392 8.1E-66 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 Gene3D G3DSA:1.10.8.60 325 392 1.5E-23 T 13-09-2016 THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 237 252 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 175 188 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 Pfam PF02954 Bacterial regulatory protein, Fis family 426 466 5.6E-10 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 Gene3D G3DSA:1.10.10.60 420 469 4.0E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 Gene3D G3DSA:3.40.50.300 142 323 3.9E-49 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 SMART SM00382 171 322 1.4E-5 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 432 449 4.1E-9 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 449 469 4.1E-9 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 364 373 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 Gene3D G3DSA:3.40.50.2300 4 130 1.6E-37 T 13-09-2016 THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 Pfam PF00158 Sigma-54 interaction domain 156 318 2.0E-62 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 SMART SM00448 3 114 1.0E-32 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS24850 ced557036480cefde04a57fd90f088fb 476 Pfam PF00072 Response regulator receiver domain 5 113 2.9E-27 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS05905 8a1418011945585875cd11d90b1819c9 196 PANTHER PTHR35603 2 189 4.3E-82 T 13-09-2016 THL1_RS05905 8a1418011945585875cd11d90b1819c9 196 Pfam PF05433 Glycine zipper 2TM domain 73 114 6.2E-10 T 13-09-2016 IPR008816 Glycine zipper 2TM domain GO:0019867 THL1_RS05905 8a1418011945585875cd11d90b1819c9 196 PANTHER PTHR35603:SF2 2 189 4.3E-82 T 13-09-2016 THL1_RS19780 5941e0145f4d839cdde0b0907f92f525 386 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS19780 5941e0145f4d839cdde0b0907f92f525 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 220 2.6E-25 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS19780 5941e0145f4d839cdde0b0907f92f525 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 380 4.4E-51 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS19780 5941e0145f4d839cdde0b0907f92f525 386 SUPERFAMILY SSF47203 230 382 1.45E-54 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS19780 5941e0145f4d839cdde0b0907f92f525 386 SUPERFAMILY SSF56645 1 243 5.63E-69 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS19780 5941e0145f4d839cdde0b0907f92f525 386 Gene3D G3DSA:2.40.110.10 121 221 1.3E-37 T 13-09-2016 THL1_RS19780 5941e0145f4d839cdde0b0907f92f525 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 339 358 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS19780 5941e0145f4d839cdde0b0907f92f525 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 5.9E-18 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS19780 5941e0145f4d839cdde0b0907f92f525 386 PANTHER PTHR10909 1 382 8.7E-235 T 13-09-2016 THL1_RS19780 5941e0145f4d839cdde0b0907f92f525 386 PANTHER PTHR10909:SF278 1 382 8.7E-235 T 13-09-2016 THL1_RS19780 5941e0145f4d839cdde0b0907f92f525 386 Gene3D G3DSA:1.10.540.10 1 119 3.5E-23 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS19780 5941e0145f4d839cdde0b0907f92f525 386 Gene3D G3DSA:1.20.140.10 222 382 3.2E-68 T 13-09-2016 THL1_RS21600 1c9f279c307d5cfb4440be8262c3fa8d 108 Gene3D G3DSA:3.40.30.10 7 102 1.9E-31 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS21600 1c9f279c307d5cfb4440be8262c3fa8d 108 PIRSF PIRSF005894 1 107 1.5E-49 T 13-09-2016 IPR014434 Monothiol glutaredoxin THL1_RS21600 1c9f279c307d5cfb4440be8262c3fa8d 108 SUPERFAMILY SSF52833 1 101 9.09E-34 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS21600 1c9f279c307d5cfb4440be8262c3fa8d 108 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 4 100 3.0E-46 T 13-09-2016 IPR004480 Monothiol glutaredoxin-related THL1_RS21600 1c9f279c307d5cfb4440be8262c3fa8d 108 PANTHER PTHR10293 1 102 6.0E-56 T 13-09-2016 IPR004480 Monothiol glutaredoxin-related THL1_RS21600 1c9f279c307d5cfb4440be8262c3fa8d 108 Pfam PF00462 Glutaredoxin 16 80 2.2E-18 T 13-09-2016 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 THL1_RS06575 2f18d2123d83b28b76217d96989fcce2 368 PANTHER PTHR12169 313 364 1.6E-132 T 13-09-2016 IPR005654 ATPase, AFG1-like GO:0005524 THL1_RS06575 2f18d2123d83b28b76217d96989fcce2 368 PANTHER PTHR12169 1 283 1.6E-132 T 13-09-2016 IPR005654 ATPase, AFG1-like GO:0005524 THL1_RS06575 2f18d2123d83b28b76217d96989fcce2 368 PANTHER PTHR12169:SF11 313 364 1.6E-132 T 13-09-2016 THL1_RS06575 2f18d2123d83b28b76217d96989fcce2 368 Pfam PF03969 AFG1-like ATPase 306 365 2.0E-13 T 13-09-2016 IPR005654 ATPase, AFG1-like GO:0005524 THL1_RS06575 2f18d2123d83b28b76217d96989fcce2 368 Pfam PF03969 AFG1-like ATPase 9 283 5.6E-82 T 13-09-2016 IPR005654 ATPase, AFG1-like GO:0005524 THL1_RS06575 2f18d2123d83b28b76217d96989fcce2 368 PANTHER PTHR12169:SF11 1 283 1.6E-132 T 13-09-2016 THL1_RS06575 2f18d2123d83b28b76217d96989fcce2 368 Gene3D G3DSA:3.40.50.300 17 154 1.6E-23 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06575 2f18d2123d83b28b76217d96989fcce2 368 SUPERFAMILY SSF52540 41 168 2.1E-14 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14200 1af6e5d58fe24394b812673fcc5334ad 420 SMART SM00387 326 417 5.4E-5 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS14200 1af6e5d58fe24394b812673fcc5334ad 420 SUPERFAMILY SSF55874 300 416 3.67E-17 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS14200 1af6e5d58fe24394b812673fcc5334ad 420 Gene3D G3DSA:3.30.565.10 310 416 1.8E-7 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS14200 1af6e5d58fe24394b812673fcc5334ad 420 Pfam PF00672 HAMP domain 134 202 3.0E-11 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS14200 1af6e5d58fe24394b812673fcc5334ad 420 SUPERFAMILY SSF158472 157 203 1.44E-5 T 13-09-2016 THL1_RS14200 1af6e5d58fe24394b812673fcc5334ad 420 PANTHER PTHR24421:SF1 196 416 1.5E-39 T 13-09-2016 THL1_RS14200 1af6e5d58fe24394b812673fcc5334ad 420 PANTHER PTHR24421 196 416 1.5E-39 T 13-09-2016 THL1_RS14200 1af6e5d58fe24394b812673fcc5334ad 420 SMART SM00304 154 206 1.5E-6 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS14200 1af6e5d58fe24394b812673fcc5334ad 420 Pfam PF07730 Histidine kinase 222 287 1.1E-8 T 13-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 THL1_RS14200 1af6e5d58fe24394b812673fcc5334ad 420 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 329 375 1.0E-5 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS00400 ba624a6ee2bf34d95697b8c1e5e5e2c6 472 PANTHER PTHR11455 1 446 1.1E-161 T 13-09-2016 THL1_RS00400 ba624a6ee2bf34d95697b8c1e5e5e2c6 472 PANTHER PTHR11455:SF22 1 446 1.1E-161 T 13-09-2016 IPR014133 Cryptochrome DASH GO:0003913|GO:0006281 THL1_RS00400 ba624a6ee2bf34d95697b8c1e5e5e2c6 472 Pfam PF03441 FAD binding domain of DNA photolyase 284 455 5.3E-50 T 13-09-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain THL1_RS00400 ba624a6ee2bf34d95697b8c1e5e5e2c6 472 Gene3D G3DSA:1.25.40.80 146 292 1.4E-46 T 13-09-2016 THL1_RS00400 ba624a6ee2bf34d95697b8c1e5e5e2c6 472 PRINTS PR00147 DNA photolyase signature 389 403 4.5E-11 T 13-09-2016 IPR002081 Cryptochrome/DNA photolyase class 1 THL1_RS00400 ba624a6ee2bf34d95697b8c1e5e5e2c6 472 PRINTS PR00147 DNA photolyase signature 330 346 4.5E-11 T 13-09-2016 IPR002081 Cryptochrome/DNA photolyase class 1 THL1_RS00400 ba624a6ee2bf34d95697b8c1e5e5e2c6 472 PRINTS PR00147 DNA photolyase signature 350 368 4.5E-11 T 13-09-2016 IPR002081 Cryptochrome/DNA photolyase class 1 THL1_RS00400 ba624a6ee2bf34d95697b8c1e5e5e2c6 472 Pfam PF00875 DNA photolyase 4 169 2.6E-32 T 13-09-2016 IPR006050 DNA photolyase, N-terminal THL1_RS00400 ba624a6ee2bf34d95697b8c1e5e5e2c6 472 Gene3D G3DSA:1.10.579.10 293 456 3.6E-59 T 13-09-2016 THL1_RS00400 ba624a6ee2bf34d95697b8c1e5e5e2c6 472 SUPERFAMILY SSF52425 4 180 1.22E-40 T 13-09-2016 IPR006050 DNA photolyase, N-terminal THL1_RS00400 ba624a6ee2bf34d95697b8c1e5e5e2c6 472 TIGRFAM TIGR02765 crypto_DASH: cryptochrome, DASH family 3 430 1.6E-141 T 13-09-2016 IPR014133 Cryptochrome DASH GO:0003913|GO:0006281 THL1_RS00400 ba624a6ee2bf34d95697b8c1e5e5e2c6 472 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 330 342 - T 13-09-2016 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal THL1_RS00400 ba624a6ee2bf34d95697b8c1e5e5e2c6 472 Gene3D G3DSA:3.40.50.620 2 145 1.6E-36 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS00400 ba624a6ee2bf34d95697b8c1e5e5e2c6 472 SUPERFAMILY SSF48173 204 455 1.31E-79 T 13-09-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain THL1_RS27535 8a8a1ea6d7a3ba644290709f52e951b1 112 SMART SM00938 4 105 4.6E-66 T 13-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THL1_RS27535 8a8a1ea6d7a3ba644290709f52e951b1 112 Gene3D G3DSA:3.30.70.120 1 112 2.8E-50 T 13-09-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THL1_RS27535 8a8a1ea6d7a3ba644290709f52e951b1 112 PRINTS PR00340 P-II protein signature 23 41 1.5E-43 T 13-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THL1_RS27535 8a8a1ea6d7a3ba644290709f52e951b1 112 PRINTS PR00340 P-II protein signature 83 103 1.5E-43 T 13-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THL1_RS27535 8a8a1ea6d7a3ba644290709f52e951b1 112 PRINTS PR00340 P-II protein signature 2 17 1.5E-43 T 13-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THL1_RS27535 8a8a1ea6d7a3ba644290709f52e951b1 112 PRINTS PR00340 P-II protein signature 52 75 1.5E-43 T 13-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THL1_RS27535 8a8a1ea6d7a3ba644290709f52e951b1 112 PIRSF PIRSF039144 1 112 3.8E-55 T 13-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THL1_RS27535 8a8a1ea6d7a3ba644290709f52e951b1 112 SUPERFAMILY SSF54913 1 112 3.18E-45 T 13-09-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta THL1_RS27535 8a8a1ea6d7a3ba644290709f52e951b1 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 4.7E-43 T 13-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THL1_RS27535 8a8a1ea6d7a3ba644290709f52e951b1 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 13-09-2016 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 THL1_RS27535 8a8a1ea6d7a3ba644290709f52e951b1 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 13-09-2016 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 THL1_RS27535 8a8a1ea6d7a3ba644290709f52e951b1 112 PANTHER PTHR30115:SF12 1 112 2.6E-80 T 13-09-2016 THL1_RS27535 8a8a1ea6d7a3ba644290709f52e951b1 112 PANTHER PTHR30115 1 112 2.6E-80 T 13-09-2016 THL1_RS11490 d29c2544b6fa02c001b5aedbdc7faad0 188 Gene3D G3DSA:2.30.30.30 1 62 1.8E-23 T 13-09-2016 IPR014722 Ribosomal protein L2 domain 2 THL1_RS11490 d29c2544b6fa02c001b5aedbdc7faad0 188 SMART SM00841 130 185 1.8E-24 T 13-09-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 THL1_RS11490 d29c2544b6fa02c001b5aedbdc7faad0 188 Pfam PF09285 Elongation factor P, C-terminal 130 185 6.7E-21 T 13-09-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 THL1_RS11490 d29c2544b6fa02c001b5aedbdc7faad0 188 Gene3D G3DSA:2.40.50.140 129 186 1.4E-23 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS11490 d29c2544b6fa02c001b5aedbdc7faad0 188 PIRSF PIRSF005901 1 187 8.8E-57 T 13-09-2016 IPR020599 Translation elongation factor P/YeiP UniPathway: UPA00345 THL1_RS11490 d29c2544b6fa02c001b5aedbdc7faad0 188 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 122 1.5E-12 T 13-09-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 THL1_RS11490 d29c2544b6fa02c001b5aedbdc7faad0 188 SMART SM01185 67 122 9.9E-14 T 13-09-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 THL1_RS11490 d29c2544b6fa02c001b5aedbdc7faad0 188 Hamap MF_00141 Elongation factor P [efp]. 1 186 48.168 T 13-09-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 THL1_RS11490 d29c2544b6fa02c001b5aedbdc7faad0 188 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 1.5E-21 T 13-09-2016 IPR013185 Translation elongation factor, KOW-like UniPathway: UPA00345 THL1_RS11490 d29c2544b6fa02c001b5aedbdc7faad0 188 Gene3D G3DSA:2.40.50.140 65 128 2.7E-16 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS11490 d29c2544b6fa02c001b5aedbdc7faad0 188 SUPERFAMILY SSF50104 1 62 3.91E-17 T 13-09-2016 IPR008991 Translation protein SH3-like domain THL1_RS11490 d29c2544b6fa02c001b5aedbdc7faad0 188 PANTHER PTHR30053 1 187 1.8E-70 T 13-09-2016 THL1_RS11490 d29c2544b6fa02c001b5aedbdc7faad0 188 SUPERFAMILY SSF50249 130 186 7.2E-15 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS11490 d29c2544b6fa02c001b5aedbdc7faad0 188 TIGRFAM TIGR00038 efp: translation elongation factor P 3 186 2.5E-60 T 13-09-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 THL1_RS11490 d29c2544b6fa02c001b5aedbdc7faad0 188 SUPERFAMILY SSF50249 65 128 6.43E-12 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS05710 8fc7f23dcc0b171e52f88bd2e02f45a3 191 PANTHER PTHR12213 4 191 2.0E-80 T 13-09-2016 THL1_RS05710 8fc7f23dcc0b171e52f88bd2e02f45a3 191 PANTHER PTHR12213:SF0 4 191 2.0E-80 T 13-09-2016 THL1_RS05710 8fc7f23dcc0b171e52f88bd2e02f45a3 191 Gene3D G3DSA:1.20.1200.10 17 188 3.9E-60 T 13-09-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 THL1_RS05710 8fc7f23dcc0b171e52f88bd2e02f45a3 191 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 9 186 3.9E-52 T 13-09-2016 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 THL1_RS05710 8fc7f23dcc0b171e52f88bd2e02f45a3 191 Pfam PF01923 Cobalamin adenosyltransferase 8 173 4.7E-55 T 13-09-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 THL1_RS05710 8fc7f23dcc0b171e52f88bd2e02f45a3 191 SUPERFAMILY SSF89028 7 186 7.06E-60 T 13-09-2016 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 THL1_RS05710 8fc7f23dcc0b171e52f88bd2e02f45a3 191 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 186 6.0E-73 T 13-09-2016 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 THL1_RS20770 47f298d48f27af4041663a19018f1cd6 101 Pfam PF12840 Helix-turn-helix domain 10 67 5.9E-12 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20770 47f298d48f27af4041663a19018f1cd6 101 Gene3D G3DSA:1.10.10.10 1 92 1.9E-31 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20770 47f298d48f27af4041663a19018f1cd6 101 SUPERFAMILY SSF46785 4 91 2.07E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20770 47f298d48f27af4041663a19018f1cd6 101 PANTHER PTHR33154:SF10 1 100 5.6E-29 T 13-09-2016 THL1_RS20770 47f298d48f27af4041663a19018f1cd6 101 SMART SM00418 10 88 1.8E-23 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS20770 47f298d48f27af4041663a19018f1cd6 101 PANTHER PTHR33154 1 100 5.6E-29 T 13-09-2016 THL1_RS20770 47f298d48f27af4041663a19018f1cd6 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 7.7E-13 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS20770 47f298d48f27af4041663a19018f1cd6 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 7.7E-13 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS20770 47f298d48f27af4041663a19018f1cd6 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 7.7E-13 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS16190 dac9c040a2a938cd953cbfbd0739324b 171 Pfam PF04985 Phage tail tube protein FII 4 170 9.2E-61 T 13-09-2016 IPR006498 Tail tube protein THL1_RS16190 dac9c040a2a938cd953cbfbd0739324b 171 TIGRFAM TIGR01611 tail_tube: phage major tail tube protein 3 171 1.5E-46 T 13-09-2016 IPR006498 Tail tube protein THL1_RS16190 dac9c040a2a938cd953cbfbd0739324b 171 PANTHER PTHR35861:SF2 1 171 2.4E-58 T 13-09-2016 THL1_RS16190 dac9c040a2a938cd953cbfbd0739324b 171 PANTHER PTHR35861 1 171 2.4E-58 T 13-09-2016 THL1_RS08690 47acdf783fc1e2fa6179b489ef56f92a 777 Pfam PF00884 Sulfatase 223 501 6.6E-35 T 13-09-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 THL1_RS08690 47acdf783fc1e2fa6179b489ef56f92a 777 Gene3D G3DSA:3.40.720.10 224 513 2.7E-29 T 13-09-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THL1_RS08690 47acdf783fc1e2fa6179b489ef56f92a 777 SUPERFAMILY SSF53649 222 550 1.06E-44 T 13-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THL1_RS08690 47acdf783fc1e2fa6179b489ef56f92a 777 PANTHER PTHR10342 278 535 2.4E-54 T 13-09-2016 THL1_RS08690 47acdf783fc1e2fa6179b489ef56f92a 777 PANTHER PTHR10342:SF237 278 535 2.4E-54 T 13-09-2016 THL1_RS27180 50c4c80428ed7e1fa4e213b02ed2ded6 157 SMART SM00344 5 114 1.7E-39 T 13-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 THL1_RS27180 50c4c80428ed7e1fa4e213b02ed2ded6 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 7.4E-15 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS27180 50c4c80428ed7e1fa4e213b02ed2ded6 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 7.4E-15 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS27180 50c4c80428ed7e1fa4e213b02ed2ded6 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 7.4E-15 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS27180 50c4c80428ed7e1fa4e213b02ed2ded6 157 Gene3D G3DSA:1.10.10.10 2 55 2.3E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS27180 50c4c80428ed7e1fa4e213b02ed2ded6 157 PANTHER PTHR30154 1 154 2.0E-85 T 13-09-2016 THL1_RS27180 50c4c80428ed7e1fa4e213b02ed2ded6 157 SUPERFAMILY SSF54909 66 154 4.02E-20 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS27180 50c4c80428ed7e1fa4e213b02ed2ded6 157 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 4.7E-20 T 13-09-2016 THL1_RS27180 50c4c80428ed7e1fa4e213b02ed2ded6 157 Gene3D G3DSA:3.30.70.920 58 154 3.4E-29 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS27180 50c4c80428ed7e1fa4e213b02ed2ded6 157 PANTHER PTHR30154:SF17 1 154 2.0E-85 T 13-09-2016 THL1_RS27180 50c4c80428ed7e1fa4e213b02ed2ded6 157 SUPERFAMILY SSF46785 5 94 7.1E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS27180 50c4c80428ed7e1fa4e213b02ed2ded6 157 ProSitePatterns PS00519 AsnC-type HTH domain signature. 23 49 - T 13-09-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site THL1_RS27180 50c4c80428ed7e1fa4e213b02ed2ded6 157 Pfam PF01037 Lrp/AsnC ligand binding domain 72 145 7.0E-21 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 SMART SM00448 13 127 2.9E-31 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 SMART SM00052 448 694 3.1E-107 T 13-09-2016 IPR001633 EAL domain THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 SMART SM00091 152 218 1.6E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 Gene3D G3DSA:3.40.50.2300 15 140 8.7E-34 T 13-09-2016 THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 SUPERFAMILY SSF55073 282 440 1.73E-52 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 Gene3D G3DSA:3.30.70.270 279 445 2.5E-60 T 13-09-2016 THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 Gene3D G3DSA:3.20.20.450 452 698 1.6E-91 T 13-09-2016 IPR001633 EAL domain THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 Gene3D G3DSA:3.30.450.20 147 262 7.6E-16 T 13-09-2016 THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 Pfam PF00563 EAL domain 454 688 3.0E-69 T 13-09-2016 IPR001633 EAL domain THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 SMART SM00267 266 438 2.9E-68 T 13-09-2016 IPR000160 GGDEF domain THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 Pfam PF00989 PAS fold 155 204 3.7E-6 T 13-09-2016 IPR013767 PAS fold GO:0006355 THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 PANTHER PTHR33121:SF13 426 698 5.3E-84 T 13-09-2016 THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 SUPERFAMILY SSF141868 453 701 1.83E-85 T 13-09-2016 IPR001633 EAL domain THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 SUPERFAMILY SSF52172 15 162 1.71E-34 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 SUPERFAMILY SSF55785 139 254 1.38E-11 T 13-09-2016 IPR000014 PAS domain THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 273 436 3.6E-45 T 13-09-2016 IPR000160 GGDEF domain THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 Pfam PF00990 Diguanylate cyclase, GGDEF domain 277 434 5.6E-49 T 13-09-2016 IPR000160 GGDEF domain THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 PANTHER PTHR33121 426 698 5.3E-84 T 13-09-2016 THL1_RS23685 9a11fe7c497990139a7a7578b59cae62 718 Pfam PF00072 Response regulator receiver domain 16 127 5.2E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS14250 f26ca354700d03da97c844dd2e4bd6d0 523 Gene3D G3DSA:1.10.287.950 90 301 3.6E-47 T 13-09-2016 THL1_RS14250 f26ca354700d03da97c844dd2e4bd6d0 523 SUPERFAMILY SSF58104 62 335 2.09E-57 T 13-09-2016 THL1_RS14250 f26ca354700d03da97c844dd2e4bd6d0 523 PANTHER PTHR32089:SF34 53 339 2.5E-81 T 13-09-2016 THL1_RS14250 f26ca354700d03da97c844dd2e4bd6d0 523 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 134 332 2.2E-44 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS14250 f26ca354700d03da97c844dd2e4bd6d0 523 SMART SM00283 75 336 9.0E-45 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS14250 f26ca354700d03da97c844dd2e4bd6d0 523 PANTHER PTHR32089 53 339 2.5E-81 T 13-09-2016 THL1_RS22335 2951a6c37ada374797bffa7375f35ed6 351 Gene3D G3DSA:3.30.1490.100 240 351 3.2E-33 T 13-09-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS22335 2951a6c37ada374797bffa7375f35ed6 351 SUPERFAMILY SSF56672 3 236 3.74E-93 T 13-09-2016 THL1_RS22335 2951a6c37ada374797bffa7375f35ed6 351 SUPERFAMILY SSF100879 244 350 6.47E-22 T 13-09-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS22335 2951a6c37ada374797bffa7375f35ed6 351 PANTHER PTHR11076 4 351 2.1E-186 T 13-09-2016 THL1_RS22335 2951a6c37ada374797bffa7375f35ed6 351 Pfam PF00817 impB/mucB/samB family 9 156 5.0E-51 T 13-09-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS22335 2951a6c37ada374797bffa7375f35ed6 351 Pfam PF11798 IMS family HHH motif 168 199 6.8E-7 T 13-09-2016 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS22335 2951a6c37ada374797bffa7375f35ed6 351 Hamap MF_01113 DNA polymerase IV [dinB]. 3 350 37.776 T 13-09-2016 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS22335 2951a6c37ada374797bffa7375f35ed6 351 PANTHER PTHR11076:SF32 4 351 2.1E-186 T 13-09-2016 THL1_RS22335 2951a6c37ada374797bffa7375f35ed6 351 Gene3D G3DSA:1.10.150.20 167 237 4.0E-28 T 13-09-2016 THL1_RS22335 2951a6c37ada374797bffa7375f35ed6 351 Gene3D G3DSA:3.30.70.270 68 166 1.1E-33 T 13-09-2016 THL1_RS13775 e89badf33b8543b1f7e0be647175bedc 260 SUPERFAMILY SSF51735 2 250 7.75E-77 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS13775 e89badf33b8543b1f7e0be647175bedc 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 1.5E-5 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13775 e89badf33b8543b1f7e0be647175bedc 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.5E-5 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13775 e89badf33b8543b1f7e0be647175bedc 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 1.5E-5 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13775 e89badf33b8543b1f7e0be647175bedc 260 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 178 4.6E-4 T 13-09-2016 THL1_RS13775 e89badf33b8543b1f7e0be647175bedc 260 Gene3D G3DSA:3.40.50.720 2 250 3.6E-76 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS13775 e89badf33b8543b1f7e0be647175bedc 260 PANTHER PTHR24322 8 130 1.2E-45 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13775 e89badf33b8543b1f7e0be647175bedc 260 PANTHER PTHR24322 146 178 1.2E-45 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13775 e89badf33b8543b1f7e0be647175bedc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 7.0E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13775 e89badf33b8543b1f7e0be647175bedc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 7.0E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13775 e89badf33b8543b1f7e0be647175bedc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 7.0E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13775 e89badf33b8543b1f7e0be647175bedc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 7.0E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13775 e89badf33b8543b1f7e0be647175bedc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 7.0E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13775 e89badf33b8543b1f7e0be647175bedc 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 7.0E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13775 e89badf33b8543b1f7e0be647175bedc 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 247 2.6E-62 T 13-09-2016 THL1_RS13775 e89badf33b8543b1f7e0be647175bedc 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS00805 3b07592a73a70b06177c54c059ec8202 553 PANTHER PTHR13707 83 275 2.2E-97 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS00805 3b07592a73a70b06177c54c059ec8202 553 PANTHER PTHR13707:SF27 83 275 2.2E-97 T 13-09-2016 THL1_RS00805 3b07592a73a70b06177c54c059ec8202 553 SUPERFAMILY SSF100950 41 282 5.44E-34 T 13-09-2016 THL1_RS00805 3b07592a73a70b06177c54c059ec8202 553 SUPERFAMILY SSF100950 230 499 8.93E-21 T 13-09-2016 THL1_RS00805 3b07592a73a70b06177c54c059ec8202 553 TIGRFAM TIGR01110 mdcA: malonate decarboxylase, alpha subunit 11 553 0.0 T 13-09-2016 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 THL1_RS00805 3b07592a73a70b06177c54c059ec8202 553 Gene3D G3DSA:3.40.1080.10 41 234 1.6E-9 T 13-09-2016 THL1_RS00805 3b07592a73a70b06177c54c059ec8202 553 Pfam PF16957 Malonate decarboxylase, alpha subunit, transporter 10 553 2.7E-296 T 13-09-2016 IPR005777 Acetyl-S-ACP:malonate ACP transferase MetaCyc: PWY-5794|MetaCyc: PWY-6060 THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 SMART SM00304 255 307 3.3E-10 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 SUPERFAMILY SSF158472 258 306 6.54E-8 T 13-09-2016 THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 Gene3D G3DSA:3.30.565.10 360 534 1.8E-36 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 Pfam PF00512 His Kinase A (phospho-acceptor) domain 309 373 2.8E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 SUPERFAMILY SSF55874 362 532 6.29E-37 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 423 530 4.9E-20 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 484 2.2E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 PRINTS PR00344 Bacterial sensor protein C-terminal signature 491 509 2.2E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 529 2.2E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 470 2.2E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 Gene3D G3DSA:1.10.287.130 298 359 7.9E-17 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 SMART SM00388 308 373 2.9E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 SUPERFAMILY SSF47384 291 373 8.04E-17 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 Pfam PF00672 HAMP domain 236 304 2.9E-12 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 PANTHER PTHR24423 4 29 4.4E-68 T 13-09-2016 THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 PANTHER PTHR24423 118 196 4.4E-68 T 13-09-2016 THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 SMART SM00387 421 532 4.0E-30 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 PANTHER PTHR24423:SF564 4 29 4.4E-68 T 13-09-2016 THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 PANTHER PTHR24423:SF564 249 532 4.4E-68 T 13-09-2016 THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 PANTHER PTHR24423:SF564 118 196 4.4E-68 T 13-09-2016 THL1_RS08905 658ad7fc73d0c82584adf5e184ebeae4 538 PANTHER PTHR24423 249 532 4.4E-68 T 13-09-2016 THL1_RS12010 341db1f076cb5bb7a24daf229e282a95 113 Gene3D G3DSA:3.10.50.40 3 108 3.8E-44 T 13-09-2016 THL1_RS12010 341db1f076cb5bb7a24daf229e282a95 113 PANTHER PTHR10516 5 113 2.6E-48 T 13-09-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type THL1_RS12010 341db1f076cb5bb7a24daf229e282a95 113 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 17 106 1.9E-32 T 13-09-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 THL1_RS12010 341db1f076cb5bb7a24daf229e282a95 113 SUPERFAMILY SSF54534 3 108 1.61E-40 T 13-09-2016 THL1_RS07555 e7870f5758253a60d3b7abb9fd84119f 493 Gene3D G3DSA:1.10.530.10 321 485 5.4E-32 T 13-09-2016 THL1_RS07555 e7870f5758253a60d3b7abb9fd84119f 493 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 77 286 6.3E-18 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS07555 e7870f5758253a60d3b7abb9fd84119f 493 SMART SM00062 64 307 4.2E-5 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS07555 e7870f5758253a60d3b7abb9fd84119f 493 SUPERFAMILY SSF53850 65 290 6.52E-27 T 13-09-2016 THL1_RS07555 e7870f5758253a60d3b7abb9fd84119f 493 Pfam PF01464 Transglycosylase SLT domain 329 441 6.1E-15 T 13-09-2016 IPR008258 Transglycosylase SLT domain 1 THL1_RS07555 e7870f5758253a60d3b7abb9fd84119f 493 PANTHER PTHR21666 309 479 6.8E-30 T 13-09-2016 THL1_RS07555 e7870f5758253a60d3b7abb9fd84119f 493 SUPERFAMILY SSF53955 326 483 3.12E-31 T 13-09-2016 IPR023346 Lysozyme-like domain THL1_RS07555 e7870f5758253a60d3b7abb9fd84119f 493 Gene3D G3DSA:3.40.190.10 149 244 1.4E-7 T 13-09-2016 THL1_RS07555 e7870f5758253a60d3b7abb9fd84119f 493 Gene3D G3DSA:3.40.190.10 62 148 1.5E-14 T 13-09-2016 THL1_RS07555 e7870f5758253a60d3b7abb9fd84119f 493 Gene3D G3DSA:3.40.190.10 261 295 1.5E-14 T 13-09-2016 THL1_RS20645 bc7c9c2acdf92b505561ec928a5ab741 395 Pfam PF00108 Thiolase, N-terminal domain 6 263 2.6E-87 T 13-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THL1_RS20645 bc7c9c2acdf92b505561ec928a5ab741 395 PIRSF PIRSF000429 1 395 4.9E-127 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS20645 bc7c9c2acdf92b505561ec928a5ab741 395 PANTHER PTHR18919:SF95 1 395 2.9E-180 T 13-09-2016 THL1_RS20645 bc7c9c2acdf92b505561ec928a5ab741 395 SUPERFAMILY SSF53901 6 272 1.36E-81 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20645 bc7c9c2acdf92b505561ec928a5ab741 395 SUPERFAMILY SSF53901 272 394 5.76E-42 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20645 bc7c9c2acdf92b505561ec928a5ab741 395 Gene3D G3DSA:3.40.47.10 6 126 3.4E-66 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20645 bc7c9c2acdf92b505561ec928a5ab741 395 Gene3D G3DSA:3.40.47.10 196 277 3.4E-66 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20645 bc7c9c2acdf92b505561ec928a5ab741 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 393 4.1E-134 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS20645 bc7c9c2acdf92b505561ec928a5ab741 395 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 13-09-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 THL1_RS20645 bc7c9c2acdf92b505561ec928a5ab741 395 PANTHER PTHR18919 1 395 2.9E-180 T 13-09-2016 THL1_RS20645 bc7c9c2acdf92b505561ec928a5ab741 395 Pfam PF02803 Thiolase, C-terminal domain 272 394 2.2E-42 T 13-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THL1_RS20645 bc7c9c2acdf92b505561ec928a5ab741 395 ProSitePatterns PS00099 Thiolases active site. 376 389 - T 13-09-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 THL1_RS20645 bc7c9c2acdf92b505561ec928a5ab741 395 Gene3D G3DSA:3.40.47.10 279 394 3.5E-59 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20645 bc7c9c2acdf92b505561ec928a5ab741 395 Gene3D G3DSA:3.40.47.10 149 195 3.5E-59 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS23665 6995a913797c11312ffff756cd68b52c 388 PANTHER PTHR21060 2 387 1.0E-165 T 13-09-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 THL1_RS23665 6995a913797c11312ffff756cd68b52c 388 PRINTS PR00471 Acetate kinase family signature 200 221 7.9E-31 T 13-09-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 THL1_RS23665 6995a913797c11312ffff756cd68b52c 388 PRINTS PR00471 Acetate kinase family signature 313 329 7.9E-31 T 13-09-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 THL1_RS23665 6995a913797c11312ffff756cd68b52c 388 PRINTS PR00471 Acetate kinase family signature 170 183 7.9E-31 T 13-09-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 THL1_RS23665 6995a913797c11312ffff756cd68b52c 388 PRINTS PR00471 Acetate kinase family signature 368 380 7.9E-31 T 13-09-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 THL1_RS23665 6995a913797c11312ffff756cd68b52c 388 PRINTS PR00471 Acetate kinase family signature 291 304 7.9E-31 T 13-09-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 THL1_RS23665 6995a913797c11312ffff756cd68b52c 388 PRINTS PR00471 Acetate kinase family signature 6 17 7.9E-31 T 13-09-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 THL1_RS23665 6995a913797c11312ffff756cd68b52c 388 Pfam PF00871 Acetokinase family 6 380 8.8E-92 T 13-09-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 THL1_RS23665 6995a913797c11312ffff756cd68b52c 388 PANTHER PTHR21060:SF15 2 387 1.0E-165 T 13-09-2016 THL1_RS23665 6995a913797c11312ffff756cd68b52c 388 SUPERFAMILY SSF53067 153 387 2.69E-61 T 13-09-2016 THL1_RS23665 6995a913797c11312ffff756cd68b52c 388 PIRSF PIRSF000722 2 388 5.8E-95 T 13-09-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 THL1_RS23665 6995a913797c11312ffff756cd68b52c 388 Gene3D G3DSA:3.30.420.40 152 349 1.7E-55 T 13-09-2016 THL1_RS23665 6995a913797c11312ffff756cd68b52c 388 Hamap MF_00020 Acetate kinase [ackA]. 1 388 125.685 T 13-09-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 THL1_RS23665 6995a913797c11312ffff756cd68b52c 388 TIGRFAM TIGR00016 ackA: acetate kinase 4 386 1.7E-93 T 13-09-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 THL1_RS23665 6995a913797c11312ffff756cd68b52c 388 SUPERFAMILY SSF53067 5 192 2.52E-47 T 13-09-2016 THL1_RS27025 325bddb1b0e1bce8875bd25e97324a86 273 PRINTS PR00377 Inositol monophosphatase superfamily signature 212 236 3.0E-9 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS27025 325bddb1b0e1bce8875bd25e97324a86 273 PRINTS PR00377 Inositol monophosphatase superfamily signature 83 99 3.0E-9 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS27025 325bddb1b0e1bce8875bd25e97324a86 273 PRINTS PR00377 Inositol monophosphatase superfamily signature 37 57 3.0E-9 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS27025 325bddb1b0e1bce8875bd25e97324a86 273 SUPERFAMILY SSF56655 3 267 4.19E-70 T 13-09-2016 THL1_RS27025 325bddb1b0e1bce8875bd25e97324a86 273 PANTHER PTHR20854:SF5 5 268 9.0E-77 T 13-09-2016 THL1_RS27025 325bddb1b0e1bce8875bd25e97324a86 273 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 83 96 - T 13-09-2016 IPR020583 Inositol monophosphatase, metal-binding site THL1_RS27025 325bddb1b0e1bce8875bd25e97324a86 273 Gene3D G3DSA:3.30.540.10 5 147 6.4E-42 T 13-09-2016 THL1_RS27025 325bddb1b0e1bce8875bd25e97324a86 273 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 7 254 4.4E-85 T 13-09-2016 IPR006240 3(2),5 -bisphosphate nucleotidase, bacterial GO:0000287|GO:0016020 KEGG: 00920+3.1.3.7 THL1_RS27025 325bddb1b0e1bce8875bd25e97324a86 273 PANTHER PTHR20854 5 268 9.0E-77 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS27025 325bddb1b0e1bce8875bd25e97324a86 273 Pfam PF00459 Inositol monophosphatase family 3 245 3.1E-48 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS27025 325bddb1b0e1bce8875bd25e97324a86 273 Gene3D G3DSA:3.40.190.80 153 255 1.5E-39 T 13-09-2016 THL1_RS07975 937707e4d9b5ca9bd1ec56536e3efc6e 300 PANTHER PTHR30126:SF16 8 295 1.5E-63 T 13-09-2016 THL1_RS07975 937707e4d9b5ca9bd1ec56536e3efc6e 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 9.5E-17 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS07975 937707e4d9b5ca9bd1ec56536e3efc6e 300 Gene3D G3DSA:1.10.10.10 8 86 4.1E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07975 937707e4d9b5ca9bd1ec56536e3efc6e 300 SUPERFAMILY SSF53850 97 298 5.43E-26 T 13-09-2016 THL1_RS07975 937707e4d9b5ca9bd1ec56536e3efc6e 300 PANTHER PTHR30126 8 295 1.5E-63 T 13-09-2016 THL1_RS07975 937707e4d9b5ca9bd1ec56536e3efc6e 300 SUPERFAMILY SSF46785 8 93 2.35E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07975 937707e4d9b5ca9bd1ec56536e3efc6e 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 5.6E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS07975 937707e4d9b5ca9bd1ec56536e3efc6e 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 5.6E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS07975 937707e4d9b5ca9bd1ec56536e3efc6e 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 5.6E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS07975 937707e4d9b5ca9bd1ec56536e3efc6e 300 Pfam PF03466 LysR substrate binding domain 95 296 1.1E-21 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS07975 937707e4d9b5ca9bd1ec56536e3efc6e 300 Gene3D G3DSA:3.40.190.10 96 206 9.2E-14 T 13-09-2016 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 28 321 2.2E-107 T 13-09-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 Gene3D G3DSA:2.40.240.10 461 551 3.2E-31 T 13-09-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: REACT_71 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 SUPERFAMILY SSF50715 341 552 4.66E-69 T 13-09-2016 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: REACT_71 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 PANTHER PTHR11451 11 248 7.5E-224 T 13-09-2016 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 PANTHER PTHR11451 268 555 7.5E-224 T 13-09-2016 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 341 532 3.3E-59 T 13-09-2016 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: REACT_71 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 SUPERFAMILY SSF52374 13 338 3.94E-98 T 13-09-2016 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 Gene3D G3DSA:3.40.50.620 213 263 5.1E-43 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 Gene3D G3DSA:3.40.50.620 28 97 5.1E-43 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 Gene3D G3DSA:3.90.800.10 102 210 1.5E-45 T 13-09-2016 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 61 74 8.6E-9 T 13-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 46 57 8.6E-9 T 13-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 32 44 8.6E-9 T 13-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 PRINTS PR00987 Glutamyl-tRNA synthetase signature 211 221 8.6E-9 T 13-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 PANTHER PTHR11451:SF29 11 248 7.5E-224 T 13-09-2016 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 35 46 - T 13-09-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 Gene3D G3DSA:2.40.240.10 349 460 2.9E-44 T 13-09-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: REACT_71 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 553 54.41 T 13-09-2016 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 Gene3D G3DSA:1.10.1160.10 264 339 3.1E-35 T 13-09-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: REACT_71 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 PANTHER PTHR11451:SF29 268 555 7.5E-224 T 13-09-2016 THL1_RS18035 ffbd63d78ff5a65f2eb471bb2cc40901 555 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 30 553 2.4E-228 T 13-09-2016 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18 THL1_RS15415 0fa11a48a8484e879be163584d517d46 74 PANTHER PTHR40613:SF1 1 71 3.1E-21 T 13-09-2016 THL1_RS15415 0fa11a48a8484e879be163584d517d46 74 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 2 67 3.8E-30 T 13-09-2016 IPR024530 Putative quorum-sensing-regulated virulence factor THL1_RS15415 0fa11a48a8484e879be163584d517d46 74 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 14 70 3.0E-23 T 13-09-2016 IPR024530 Putative quorum-sensing-regulated virulence factor THL1_RS15415 0fa11a48a8484e879be163584d517d46 74 PANTHER PTHR40613 1 71 3.1E-21 T 13-09-2016 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 SUPERFAMILY SSF48113 423 726 1.92E-114 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 PRINTS PR00458 Haem peroxidase superfamily signature 309 324 1.7E-18 T 13-09-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 PRINTS PR00458 Haem peroxidase superfamily signature 146 163 1.7E-18 T 13-09-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 PRINTS PR00458 Haem peroxidase superfamily signature 250 265 1.7E-18 T 13-09-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 PRINTS PR00458 Haem peroxidase superfamily signature 86 100 1.7E-18 T 13-09-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 PRINTS PR00458 Haem peroxidase superfamily signature 164 176 1.7E-18 T 13-09-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 Pfam PF00141 Peroxidase 73 388 1.3E-44 T 13-09-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 Pfam PF00141 Peroxidase 396 701 5.6E-39 T 13-09-2016 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 PANTHER PTHR30555 1 727 0.0 T 13-09-2016 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 Hamap MF_01961 Catalase-peroxidase [katG]. 2 727 42.373 T 13-09-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 PANTHER PTHR30555:SF0 1 727 0.0 T 13-09-2016 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 Gene3D G3DSA:1.10.520.10 230 242 1.9E-73 T 13-09-2016 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 Gene3D G3DSA:1.10.520.10 425 579 3.8E-62 T 13-09-2016 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 Gene3D G3DSA:1.10.520.10 705 726 3.8E-62 T 13-09-2016 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 Gene3D G3DSA:1.10.520.10 43 197 1.9E-73 T 13-09-2016 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 Gene3D G3DSA:1.10.420.10 243 265 1.3E-43 T 13-09-2016 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 Gene3D G3DSA:1.10.420.10 301 400 1.3E-43 T 13-09-2016 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 12 726 0.0 T 13-09-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 250 260 - T 13-09-2016 IPR019793 Peroxidases heam-ligand binding site THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 Gene3D G3DSA:1.10.420.10 580 701 6.6E-47 T 13-09-2016 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 SUPERFAMILY SSF48113 20 422 2.8E-149 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 ProSitePatterns PS00436 Peroxidases active site signature. 86 97 - T 13-09-2016 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 22 44 2.6E-55 T 13-09-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 473 499 2.6E-55 T 13-09-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 48 61 2.6E-55 T 13-09-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 258 281 2.6E-55 T 13-09-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 THL1_RS12990 bd5afe0ef4eafa25cd6a01b866a009b5 727 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 63 88 2.6E-55 T 13-09-2016 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 THL1_RS04100 9301619458b63371587546e8fdf9ec95 350 Pfam PF12833 Helix-turn-helix domain 270 346 5.5E-18 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS04100 9301619458b63371587546e8fdf9ec95 350 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 330 346 7.6E-7 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS04100 9301619458b63371587546e8fdf9ec95 350 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 315 330 7.6E-7 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS04100 9301619458b63371587546e8fdf9ec95 350 SMART SM00342 264 346 8.5E-25 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS04100 9301619458b63371587546e8fdf9ec95 350 PANTHER PTHR11019 199 350 7.2E-25 T 13-09-2016 THL1_RS04100 9301619458b63371587546e8fdf9ec95 350 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 37 216 7.0E-46 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS04100 9301619458b63371587546e8fdf9ec95 350 SUPERFAMILY SSF46689 300 348 1.29E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS04100 9301619458b63371587546e8fdf9ec95 350 PANTHER PTHR11019:SF52 199 350 7.2E-25 T 13-09-2016 THL1_RS04100 9301619458b63371587546e8fdf9ec95 350 Gene3D G3DSA:1.10.10.60 299 347 7.8E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01580 ae1f0847f624da1f8a8e15fb3861a0c2 191 Pfam PF04264 YceI-like domain 25 184 2.9E-38 T 13-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THL1_RS01580 ae1f0847f624da1f8a8e15fb3861a0c2 191 SUPERFAMILY SSF101874 21 190 2.49E-52 T 13-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THL1_RS01580 ae1f0847f624da1f8a8e15fb3861a0c2 191 PANTHER PTHR34406:SF1 1 190 1.8E-56 T 13-09-2016 THL1_RS01580 ae1f0847f624da1f8a8e15fb3861a0c2 191 PANTHER PTHR34406 1 190 1.8E-56 T 13-09-2016 THL1_RS01580 ae1f0847f624da1f8a8e15fb3861a0c2 191 SMART SM00867 24 189 5.4E-66 T 13-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THL1_RS01580 ae1f0847f624da1f8a8e15fb3861a0c2 191 Gene3D G3DSA:2.40.128.110 22 190 1.4E-56 T 13-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THL1_RS18375 1d88e40bb892d9820e4262015f1df6bd 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 7.8E-10 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS18375 1d88e40bb892d9820e4262015f1df6bd 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 7.8E-10 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS18375 1d88e40bb892d9820e4262015f1df6bd 200 Gene3D G3DSA:1.10.10.60 13 64 1.6E-20 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS18375 1d88e40bb892d9820e4262015f1df6bd 200 PANTHER PTHR30055:SF56 3 196 3.4E-78 T 13-09-2016 THL1_RS18375 1d88e40bb892d9820e4262015f1df6bd 200 PANTHER PTHR30055 3 196 3.4E-78 T 13-09-2016 THL1_RS18375 1d88e40bb892d9820e4262015f1df6bd 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 5.3E-16 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS18375 1d88e40bb892d9820e4262015f1df6bd 200 SUPERFAMILY SSF48498 88 196 1.06E-17 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS18375 1d88e40bb892d9820e4262015f1df6bd 200 SUPERFAMILY SSF46689 11 90 5.67E-18 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS18375 1d88e40bb892d9820e4262015f1df6bd 200 Gene3D G3DSA:1.10.357.10 65 196 1.5E-37 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS18375 1d88e40bb892d9820e4262015f1df6bd 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 13-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site THL1_RS03330 5eaa09da7a009c37eee8efa597096f98 264 Hamap MF_00465 S-adenosylmethionine decarboxylase proenzyme [speD]. 1 264 167.958 T 13-09-2016 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|UniPathway: UPA00331 THL1_RS03330 5eaa09da7a009c37eee8efa597096f98 264 PANTHER PTHR33866:SF1 113 264 2.1E-158 T 13-09-2016 THL1_RS03330 5eaa09da7a009c37eee8efa597096f98 264 PANTHER PTHR33866 16 85 2.1E-158 T 13-09-2016 THL1_RS03330 5eaa09da7a009c37eee8efa597096f98 264 PIRSF PIRSF001356 1 264 7.9E-148 T 13-09-2016 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|UniPathway: UPA00331 THL1_RS03330 5eaa09da7a009c37eee8efa597096f98 264 PANTHER PTHR33866 113 264 2.1E-158 T 13-09-2016 THL1_RS03330 5eaa09da7a009c37eee8efa597096f98 264 TIGRFAM TIGR03331 SAM_DCase_Eco: S-adenosylmethionine decarboxylase proenzyme 4 262 4.1E-146 T 13-09-2016 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|UniPathway: UPA00331 THL1_RS03330 5eaa09da7a009c37eee8efa597096f98 264 SUPERFAMILY SSF56276 113 175 4.32E-25 T 13-09-2016 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|UniPathway: UPA00331 THL1_RS03330 5eaa09da7a009c37eee8efa597096f98 264 SUPERFAMILY SSF56276 44 85 4.32E-25 T 13-09-2016 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|UniPathway: UPA00331 THL1_RS03330 5eaa09da7a009c37eee8efa597096f98 264 Pfam PF02675 S-adenosylmethionine decarboxylase 37 170 1.4E-31 T 13-09-2016 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|UniPathway: UPA00331 THL1_RS03330 5eaa09da7a009c37eee8efa597096f98 264 PANTHER PTHR33866:SF1 16 85 2.1E-158 T 13-09-2016 THL1_RS03330 5eaa09da7a009c37eee8efa597096f98 264 Gene3D G3DSA:3.60.90.10 35 187 9.1E-48 T 13-09-2016 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|UniPathway: UPA00331 THL1_RS27095 d63adba6ca5eff2166fcac36675fa311 200 Pfam PF00881 Nitroreductase family 7 177 6.2E-32 T 13-09-2016 IPR029479 Nitroreductase THL1_RS27095 d63adba6ca5eff2166fcac36675fa311 200 Gene3D G3DSA:3.40.109.10 3 195 4.5E-53 T 13-09-2016 IPR000415 Nitroreductase-like GO:0016491 THL1_RS27095 d63adba6ca5eff2166fcac36675fa311 200 PANTHER PTHR23026:SF111 2 200 4.4E-49 T 13-09-2016 THL1_RS27095 d63adba6ca5eff2166fcac36675fa311 200 PANTHER PTHR23026 2 200 4.4E-49 T 13-09-2016 THL1_RS27095 d63adba6ca5eff2166fcac36675fa311 200 SUPERFAMILY SSF55469 3 200 4.32E-48 T 13-09-2016 IPR000415 Nitroreductase-like GO:0016491 THL1_RS01265 d438628aa973bc8a221b4cc6369f7fd5 197 PANTHER PTHR11067 1 195 2.6E-76 T 13-09-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 THL1_RS01265 d438628aa973bc8a221b4cc6369f7fd5 197 PANTHER PTHR11067:SF9 1 195 2.6E-76 T 13-09-2016 THL1_RS01265 d438628aa973bc8a221b4cc6369f7fd5 197 Pfam PF01725 Ham1 family 7 193 3.3E-53 T 13-09-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 THL1_RS01265 d438628aa973bc8a221b4cc6369f7fd5 197 Gene3D G3DSA:3.90.950.10 2 195 2.1E-73 T 13-09-2016 IPR029001 Inosine triphosphate pyrophosphatase-like THL1_RS01265 d438628aa973bc8a221b4cc6369f7fd5 197 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 6 195 3.2E-55 T 13-09-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 THL1_RS01265 d438628aa973bc8a221b4cc6369f7fd5 197 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 5 197 47.457 T 13-09-2016 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 THL1_RS01265 d438628aa973bc8a221b4cc6369f7fd5 197 SUPERFAMILY SSF52972 2 195 5.49E-67 T 13-09-2016 IPR029001 Inosine triphosphate pyrophosphatase-like THL1_RS10115 55f2c6bf0fccbe76620ec41580845a8e 224 Pfam PF05036 Sporulation related domain 149 218 2.7E-17 T 13-09-2016 IPR007730 Sporulation-related domain GO:0042834 THL1_RS10115 55f2c6bf0fccbe76620ec41580845a8e 224 PANTHER PTHR38687:SF1 5 224 3.3E-41 T 13-09-2016 THL1_RS10115 55f2c6bf0fccbe76620ec41580845a8e 224 PANTHER PTHR38687 5 224 3.3E-41 T 13-09-2016 THL1_RS10115 55f2c6bf0fccbe76620ec41580845a8e 224 Gene3D G3DSA:3.30.70.1070 148 221 1.6E-21 T 13-09-2016 IPR007730 Sporulation-related domain GO:0042834 THL1_RS10115 55f2c6bf0fccbe76620ec41580845a8e 224 SUPERFAMILY SSF110997 149 220 3.27E-17 T 13-09-2016 IPR007730 Sporulation-related domain GO:0042834 THL1_RS00910 0df2559394f2746d7606ae6af7820334 212 SUPERFAMILY SSF52833 3 209 5.87E-67 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS00910 0df2559394f2746d7606ae6af7820334 212 PANTHER PTHR10681 3 207 6.3E-92 T 13-09-2016 THL1_RS00910 0df2559394f2746d7606ae6af7820334 212 Gene3D G3DSA:3.30.1020.10 158 211 1.3E-28 T 13-09-2016 THL1_RS00910 0df2559394f2746d7606ae6af7820334 212 Pfam PF00578 AhpC/TSA family 6 134 9.6E-30 T 13-09-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS00910 0df2559394f2746d7606ae6af7820334 212 Gene3D G3DSA:3.40.30.10 4 157 1.6E-59 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS00910 0df2559394f2746d7606ae6af7820334 212 PANTHER PTHR10681:SF99 3 207 6.3E-92 T 13-09-2016 THL1_RS00910 0df2559394f2746d7606ae6af7820334 212 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 193 2.6E-11 T 13-09-2016 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS00910 0df2559394f2746d7606ae6af7820334 212 PIRSF PIRSF000239 1 209 5.6E-76 T 13-09-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 THL1_RS10875 746a67b2b4ca67d204d0ad1f04186519 405 SUPERFAMILY SSF47005 105 146 2.75E-12 T 13-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 THL1_RS10875 746a67b2b4ca67d204d0ad1f04186519 405 SUPERFAMILY SSF52777 175 404 3.02E-88 T 13-09-2016 THL1_RS10875 746a67b2b4ca67d204d0ad1f04186519 405 Pfam PF00364 Biotin-requiring enzyme 4 76 1.5E-21 T 13-09-2016 IPR000089 Biotin/lipoyl attachment THL1_RS10875 746a67b2b4ca67d204d0ad1f04186519 405 Gene3D G3DSA:2.40.50.100 1 95 6.7E-28 T 13-09-2016 THL1_RS10875 746a67b2b4ca67d204d0ad1f04186519 405 Gene3D G3DSA:3.30.559.10 171 403 4.8E-92 T 13-09-2016 IPR023213 Chloramphenicol acetyltransferase-like domain THL1_RS10875 746a67b2b4ca67d204d0ad1f04186519 405 PANTHER PTHR23151 3 405 9.3E-235 T 13-09-2016 THL1_RS10875 746a67b2b4ca67d204d0ad1f04186519 405 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 13-09-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site THL1_RS10875 746a67b2b4ca67d204d0ad1f04186519 405 Gene3D G3DSA:4.10.320.10 109 149 3.7E-20 T 13-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 THL1_RS10875 746a67b2b4ca67d204d0ad1f04186519 405 PANTHER PTHR23151:SF47 3 405 9.3E-235 T 13-09-2016 THL1_RS10875 746a67b2b4ca67d204d0ad1f04186519 405 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 175 403 3.9E-81 T 13-09-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 THL1_RS10875 746a67b2b4ca67d204d0ad1f04186519 405 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 404 1.9E-186 T 13-09-2016 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|UniPathway: UPA00868 THL1_RS10875 746a67b2b4ca67d204d0ad1f04186519 405 Pfam PF02817 e3 binding domain 108 141 4.1E-16 T 13-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 THL1_RS10875 746a67b2b4ca67d204d0ad1f04186519 405 SUPERFAMILY SSF51230 1 95 8.25E-27 T 13-09-2016 IPR011053 Single hybrid motif THL1_RS14405 973171153c8c204da7fb40fa526df99a 258 SUPERFAMILY SSF51735 6 255 9.58E-67 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS14405 973171153c8c204da7fb40fa526df99a 258 PANTHER PTHR24322 12 189 4.3E-40 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14405 973171153c8c204da7fb40fa526df99a 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS14405 973171153c8c204da7fb40fa526df99a 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.5E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14405 973171153c8c204da7fb40fa526df99a 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.5E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14405 973171153c8c204da7fb40fa526df99a 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.5E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14405 973171153c8c204da7fb40fa526df99a 258 Pfam PF00106 short chain dehydrogenase 8 189 1.6E-49 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14405 973171153c8c204da7fb40fa526df99a 258 Gene3D G3DSA:3.40.50.720 1 255 9.4E-68 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS14405 973171153c8c204da7fb40fa526df99a 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.6E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14405 973171153c8c204da7fb40fa526df99a 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.6E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14405 973171153c8c204da7fb40fa526df99a 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 4.6E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14405 973171153c8c204da7fb40fa526df99a 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.6E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14405 973171153c8c204da7fb40fa526df99a 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 4.6E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14405 973171153c8c204da7fb40fa526df99a 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 4.6E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14405 973171153c8c204da7fb40fa526df99a 258 PANTHER PTHR24322:SF513 12 189 4.3E-40 T 13-09-2016 THL1_RS22760 6084f76e35283173ce6d7d48df55cc3e 385 Gene3D G3DSA:3.90.380.10 155 234 2.3E-6 T 13-09-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 THL1_RS22760 6084f76e35283173ce6d7d48df55cc3e 385 PANTHER PTHR21266 25 377 1.5E-51 T 13-09-2016 THL1_RS22760 6084f76e35283173ce6d7d48df55cc3e 385 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 188 210 4.0E-14 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS22760 6084f76e35283173ce6d7d48df55cc3e 385 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 38 63 4.0E-14 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS22760 6084f76e35283173ce6d7d48df55cc3e 385 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 108 128 4.0E-14 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS22760 6084f76e35283173ce6d7d48df55cc3e 385 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 87 107 4.0E-14 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS22760 6084f76e35283173ce6d7d48df55cc3e 385 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 197 375 3.6E-26 T 13-09-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 THL1_RS22760 6084f76e35283173ce6d7d48df55cc3e 385 SUPERFAMILY SSF55961 167 375 2.75E-31 T 13-09-2016 THL1_RS22760 6084f76e35283173ce6d7d48df55cc3e 385 SUPERFAMILY SSF50022 24 163 1.7E-35 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS22760 6084f76e35283173ce6d7d48df55cc3e 385 PANTHER PTHR21266:SF2 25 377 1.5E-51 T 13-09-2016 THL1_RS22760 6084f76e35283173ce6d7d48df55cc3e 385 Pfam PF00355 Rieske [2Fe-2S] domain 55 129 2.7E-14 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS22760 6084f76e35283173ce6d7d48df55cc3e 385 Gene3D G3DSA:2.102.10.10 52 154 4.2E-26 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS26720 17d0d45423ae1e0d5455fde1a0c76b9a 437 SMART SM00245 179 371 2.1E-73 T 13-09-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 THL1_RS26720 17d0d45423ae1e0d5455fde1a0c76b9a 437 Gene3D G3DSA:3.90.226.10 189 373 4.0E-68 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS26720 17d0d45423ae1e0d5455fde1a0c76b9a 437 Gene3D G3DSA:3.90.226.10 410 432 4.0E-68 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS26720 17d0d45423ae1e0d5455fde1a0c76b9a 437 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 60 382 1.1E-106 T 13-09-2016 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 THL1_RS26720 17d0d45423ae1e0d5455fde1a0c76b9a 437 Gene3D G3DSA:2.30.42.10 113 188 1.7E-29 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS26720 17d0d45423ae1e0d5455fde1a0c76b9a 437 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 106 174 1.3E-11 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS26720 17d0d45423ae1e0d5455fde1a0c76b9a 437 SMART SM00228 107 178 6.2E-18 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS26720 17d0d45423ae1e0d5455fde1a0c76b9a 437 Gene3D G3DSA:3.30.750.44 64 112 2.7E-11 T 13-09-2016 THL1_RS26720 17d0d45423ae1e0d5455fde1a0c76b9a 437 PANTHER PTHR32060 61 393 1.3E-124 T 13-09-2016 THL1_RS26720 17d0d45423ae1e0d5455fde1a0c76b9a 437 SUPERFAMILY SSF50156 97 180 6.09E-20 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS26720 17d0d45423ae1e0d5455fde1a0c76b9a 437 SUPERFAMILY SSF52096 198 373 3.98E-83 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS26720 17d0d45423ae1e0d5455fde1a0c76b9a 437 SUPERFAMILY SSF52096 45 125 3.98E-83 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS26720 17d0d45423ae1e0d5455fde1a0c76b9a 437 Pfam PF03572 Peptidase family S41 205 370 4.0E-56 T 13-09-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 THL1_RS12930 3c917ad01bef9a7f7d531565d57e7fb8 137 SMART SM00226 5 133 1.2E-29 T 13-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily THL1_RS12930 3c917ad01bef9a7f7d531565d57e7fb8 137 PANTHER PTHR11717 1 131 1.5E-28 T 13-09-2016 THL1_RS12930 3c917ad01bef9a7f7d531565d57e7fb8 137 PANTHER PTHR11717:SF18 1 131 1.5E-28 T 13-09-2016 THL1_RS12930 3c917ad01bef9a7f7d531565d57e7fb8 137 SUPERFAMILY SSF52788 4 130 1.96E-35 T 13-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily THL1_RS12930 3c917ad01bef9a7f7d531565d57e7fb8 137 Gene3D G3DSA:3.40.50.270 4 130 9.3E-36 T 13-09-2016 THL1_RS12930 3c917ad01bef9a7f7d531565d57e7fb8 137 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 130 4.5E-20 T 13-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily THL1_RS02675 1dc08ae054852e3d8f8e9ae3e8a09dea 222 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 13-09-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 THL1_RS02675 1dc08ae054852e3d8f8e9ae3e8a09dea 222 Gene3D G3DSA:3.20.20.70 2 220 5.1E-93 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS02675 1dc08ae054852e3d8f8e9ae3e8a09dea 222 PANTHER PTHR11749:SF7 2 222 3.5E-142 T 13-09-2016 THL1_RS02675 1dc08ae054852e3d8f8e9ae3e8a09dea 222 PIRSF PIRSF001461 1 222 2.1E-101 T 13-09-2016 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 THL1_RS02675 1dc08ae054852e3d8f8e9ae3e8a09dea 222 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 136 158 - T 13-09-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 THL1_RS02675 1dc08ae054852e3d8f8e9ae3e8a09dea 222 PANTHER PTHR11749 2 222 3.5E-142 T 13-09-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 THL1_RS02675 1dc08ae054852e3d8f8e9ae3e8a09dea 222 SUPERFAMILY SSF51366 4 218 1.47E-75 T 13-09-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 THL1_RS02675 1dc08ae054852e3d8f8e9ae3e8a09dea 222 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 6 216 6.8E-98 T 13-09-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 THL1_RS02675 1dc08ae054852e3d8f8e9ae3e8a09dea 222 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 203 2.5E-88 T 13-09-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 THL1_RS06785 70ff44eb7d000848cc2edfd2c2719342 271 SUPERFAMILY SSF52540 2 268 2.76E-52 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06785 70ff44eb7d000848cc2edfd2c2719342 271 Gene3D G3DSA:3.40.50.300 2 247 1.6E-57 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06785 70ff44eb7d000848cc2edfd2c2719342 271 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 267 7.6E-115 T 13-09-2016 IPR010223 ATP binding protein MinD, bacterial-type GO:0000918|GO:0016887 THL1_RS06785 70ff44eb7d000848cc2edfd2c2719342 271 PANTHER PTHR13696:SF1 4 257 1.7E-91 T 13-09-2016 THL1_RS06785 70ff44eb7d000848cc2edfd2c2719342 271 PIRSF PIRSF003092 1 271 8.8E-90 T 13-09-2016 IPR025501 ATP binding protein MinD THL1_RS06785 70ff44eb7d000848cc2edfd2c2719342 271 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 216 5.3E-27 T 13-09-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THL1_RS06785 70ff44eb7d000848cc2edfd2c2719342 271 PANTHER PTHR13696 4 257 1.7E-91 T 13-09-2016 THL1_RS20715 0f441abbf535e9562bda878c7e03f288 301 Pfam PF00589 Phage integrase family 133 292 4.7E-10 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS20715 0f441abbf535e9562bda878c7e03f288 301 Gene3D G3DSA:1.10.443.10 100 291 9.5E-48 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS20715 0f441abbf535e9562bda878c7e03f288 301 PANTHER PTHR30349 17 293 1.9E-14 T 13-09-2016 THL1_RS20715 0f441abbf535e9562bda878c7e03f288 301 Gene3D G3DSA:1.10.150.130 8 98 2.1E-22 T 13-09-2016 IPR023109 Integrase/recombinase, N-terminal THL1_RS20715 0f441abbf535e9562bda878c7e03f288 301 SUPERFAMILY SSF56349 100 293 7.36E-37 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS20715 0f441abbf535e9562bda878c7e03f288 301 SUPERFAMILY SSF47823 8 97 4.32E-21 T 13-09-2016 IPR010998 Integrase, Lambda-type, N-terminal THL1_RS20715 0f441abbf535e9562bda878c7e03f288 301 PANTHER PTHR30349:SF34 17 293 1.9E-14 T 13-09-2016 THL1_RS17280 2a965d938221ad6938d3ce890ca6c842 663 SUPERFAMILY SSF52540 106 554 9.03E-46 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17280 2a965d938221ad6938d3ce890ca6c842 663 PANTHER PTHR37937:SF1 9 570 2.3E-102 T 13-09-2016 THL1_RS17280 2a965d938221ad6938d3ce890ca6c842 663 Gene3D G3DSA:3.40.50.300 347 550 2.0E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17280 2a965d938221ad6938d3ce890ca6c842 663 Gene3D G3DSA:3.40.50.300 99 209 2.0E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17280 2a965d938221ad6938d3ce890ca6c842 663 PANTHER PTHR37937 9 570 2.3E-102 T 13-09-2016 THL1_RS17280 2a965d938221ad6938d3ce890ca6c842 663 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 133 555 1.6E-99 T 13-09-2016 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 THL1_RS24220 a0bb0b74e03be5c8017b00b3c828ddfe 519 PANTHER PTHR12083:SF8 398 517 2.4E-172 T 13-09-2016 THL1_RS24220 a0bb0b74e03be5c8017b00b3c828ddfe 519 Pfam PF01636 Phosphotransferase enzyme family 123 282 3.2E-8 T 13-09-2016 IPR002575 Aminoglycoside phosphotransferase THL1_RS24220 a0bb0b74e03be5c8017b00b3c828ddfe 519 Gene3D G3DSA:3.40.50.300 338 480 4.9E-20 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24220 a0bb0b74e03be5c8017b00b3c828ddfe 519 PANTHER PTHR12083 398 517 2.4E-172 T 13-09-2016 THL1_RS24220 a0bb0b74e03be5c8017b00b3c828ddfe 519 PANTHER PTHR12083 8 371 2.4E-172 T 13-09-2016 THL1_RS24220 a0bb0b74e03be5c8017b00b3c828ddfe 519 Pfam PF13671 AAA domain 338 486 5.9E-38 T 13-09-2016 THL1_RS24220 a0bb0b74e03be5c8017b00b3c828ddfe 519 Gene3D G3DSA:3.90.1200.10 125 294 7.3E-9 T 13-09-2016 THL1_RS24220 a0bb0b74e03be5c8017b00b3c828ddfe 519 SUPERFAMILY SSF56112 12 294 1.45E-24 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS24220 a0bb0b74e03be5c8017b00b3c828ddfe 519 SUPERFAMILY SSF52540 334 516 7.34E-19 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24220 a0bb0b74e03be5c8017b00b3c828ddfe 519 PANTHER PTHR12083:SF8 8 371 2.4E-172 T 13-09-2016 THL1_RS17275 b181bdca029ef6d46018cf13eb58d07b 350 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 23 206 1.3E-33 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS17275 b181bdca029ef6d46018cf13eb58d07b 350 Pfam PF12833 Helix-turn-helix domain 255 332 1.8E-15 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS17275 b181bdca029ef6d46018cf13eb58d07b 350 PANTHER PTHR11019:SF52 231 338 1.3E-23 T 13-09-2016 THL1_RS17275 b181bdca029ef6d46018cf13eb58d07b 350 SUPERFAMILY SSF46689 284 334 4.93E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17275 b181bdca029ef6d46018cf13eb58d07b 350 Gene3D G3DSA:1.10.10.60 284 335 1.2E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17275 b181bdca029ef6d46018cf13eb58d07b 350 SMART SM00342 248 330 3.8E-20 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS17275 b181bdca029ef6d46018cf13eb58d07b 350 PANTHER PTHR11019 231 338 1.3E-23 T 13-09-2016 THL1_RS15920 37f156186fe196e0e48fb5138ef1c817 232 SUPERFAMILY SSF100950 5 226 1.81E-86 T 13-09-2016 THL1_RS15920 37f156186fe196e0e48fb5138ef1c817 232 Pfam PF01144 Coenzyme A transferase 11 217 1.1E-75 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS15920 37f156186fe196e0e48fb5138ef1c817 232 PANTHER PTHR13707 1 232 4.9E-136 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS15920 37f156186fe196e0e48fb5138ef1c817 232 SMART SM00882 8 219 2.0E-88 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS15920 37f156186fe196e0e48fb5138ef1c817 232 Gene3D G3DSA:3.40.1080.10 6 217 9.4E-97 T 13-09-2016 THL1_RS15920 37f156186fe196e0e48fb5138ef1c817 232 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 20 35 - T 13-09-2016 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 THL1_RS15920 37f156186fe196e0e48fb5138ef1c817 232 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 4 217 1.3E-73 T 13-09-2016 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 THL1_RS03700 925ee169fa7ddfdc52f7688061efde50 249 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 109 141 - T 13-09-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 THL1_RS03700 925ee169fa7ddfdc52f7688061efde50 249 Gene3D G3DSA:3.40.1010.10 5 142 1.3E-33 T 13-09-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 THL1_RS03700 925ee169fa7ddfdc52f7688061efde50 249 SUPERFAMILY SSF53790 5 244 3.14E-49 T 13-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 THL1_RS03700 925ee169fa7ddfdc52f7688061efde50 249 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 226 2.3E-48 T 13-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 THL1_RS03700 925ee169fa7ddfdc52f7688061efde50 249 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 6 243 6.6E-68 T 13-09-2016 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 THL1_RS03700 925ee169fa7ddfdc52f7688061efde50 249 PIRSF PIRSF036427 4 249 1.8E-72 T 13-09-2016 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 THL1_RS03700 925ee169fa7ddfdc52f7688061efde50 249 PANTHER PTHR21091:SF127 5 242 2.2E-78 T 13-09-2016 THL1_RS03700 925ee169fa7ddfdc52f7688061efde50 249 PANTHER PTHR21091 5 242 2.2E-78 T 13-09-2016 THL1_RS19040 556c8b11a8c2ff23123496729313ecc6 314 SUPERFAMILY SSF53850 100 305 1.21E-37 T 13-09-2016 THL1_RS19040 556c8b11a8c2ff23123496729313ecc6 314 Gene3D G3DSA:1.10.10.10 15 97 1.4E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19040 556c8b11a8c2ff23123496729313ecc6 314 SUPERFAMILY SSF46785 15 99 8.68E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19040 556c8b11a8c2ff23123496729313ecc6 314 PANTHER PTHR30537:SF18 7 304 1.1E-123 T 13-09-2016 THL1_RS19040 556c8b11a8c2ff23123496729313ecc6 314 Gene3D G3DSA:3.40.190.10 103 188 1.1E-20 T 13-09-2016 THL1_RS19040 556c8b11a8c2ff23123496729313ecc6 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 74 1.3E-17 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19040 556c8b11a8c2ff23123496729313ecc6 314 Gene3D G3DSA:3.40.190.10 189 271 5.1E-22 T 13-09-2016 THL1_RS19040 556c8b11a8c2ff23123496729313ecc6 314 PANTHER PTHR30537 7 304 1.1E-123 T 13-09-2016 THL1_RS19040 556c8b11a8c2ff23123496729313ecc6 314 Pfam PF03466 LysR substrate binding domain 99 303 1.2E-36 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS08090 85075f9391814cc06dcc6aaa140f4f37 455 SUPERFAMILY SSF54862 10 137 1.35E-26 T 13-09-2016 THL1_RS08090 85075f9391814cc06dcc6aaa140f4f37 455 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 114 125 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS08090 85075f9391814cc06dcc6aaa140f4f37 455 Pfam PF14697 4Fe-4S dicluster domain 77 130 7.3E-17 T 13-09-2016 THL1_RS08090 85075f9391814cc06dcc6aaa140f4f37 455 PANTHER PTHR11938:SF64 6 136 8.1E-59 T 13-09-2016 THL1_RS08090 85075f9391814cc06dcc6aaa140f4f37 455 Gene3D G3DSA:3.30.70.20 55 143 4.1E-15 T 13-09-2016 THL1_RS08090 85075f9391814cc06dcc6aaa140f4f37 455 Pfam PF04060 Putative Fe-S cluster 14 45 1.0E-12 T 13-09-2016 IPR007202 4Fe-4S domain GO:0051536 THL1_RS08090 85075f9391814cc06dcc6aaa140f4f37 455 PANTHER PTHR11938 6 136 8.1E-59 T 13-09-2016 THL1_RS08090 85075f9391814cc06dcc6aaa140f4f37 455 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 84 95 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS08090 85075f9391814cc06dcc6aaa140f4f37 455 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 3 146 3.3E-66 T 13-09-2016 IPR010207 Electron transport complex, RnfB/RsxB GO:0009055|GO:0051536 THL1_RS08310 49c9cb008f11931424041a3097e447dd 440 PIRSF PIRSF006060 1 435 5.9E-74 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS08310 49c9cb008f11931424041a3097e447dd 440 PANTHER PTHR11785:SF346 4 439 2.9E-237 T 13-09-2016 THL1_RS08310 49c9cb008f11931424041a3097e447dd 440 Pfam PF13520 Amino acid permease 15 400 5.3E-43 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS08310 49c9cb008f11931424041a3097e447dd 440 PANTHER PTHR11785 4 439 2.9E-237 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS14110 73fa79135bf20c9fedbec7fb1bb7dc92 507 PANTHER PTHR32071:SF3 1 503 2.0E-187 T 13-09-2016 THL1_RS14110 73fa79135bf20c9fedbec7fb1bb7dc92 507 TIGRFAM TIGR04381 HTH_TypR: TyrR family helix-turn-helix domain 457 503 1.9E-23 T 13-09-2016 IPR030828 TyrR family, helix-turn-helix domain GO:0003677 THL1_RS14110 73fa79135bf20c9fedbec7fb1bb7dc92 507 Gene3D G3DSA:3.30.450.20 77 170 1.4E-9 T 13-09-2016 THL1_RS14110 73fa79135bf20c9fedbec7fb1bb7dc92 507 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 222 235 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS14110 73fa79135bf20c9fedbec7fb1bb7dc92 507 SUPERFAMILY SSF52540 199 440 1.57E-65 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14110 73fa79135bf20c9fedbec7fb1bb7dc92 507 SMART SM00091 79 144 7.4E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS14110 73fa79135bf20c9fedbec7fb1bb7dc92 507 Gene3D G3DSA:1.10.10.60 450 503 1.9E-20 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS14110 73fa79135bf20c9fedbec7fb1bb7dc92 507 PANTHER PTHR32071 1 503 2.0E-187 T 13-09-2016 THL1_RS14110 73fa79135bf20c9fedbec7fb1bb7dc92 507 SMART SM00382 218 363 4.1E-8 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS14110 73fa79135bf20c9fedbec7fb1bb7dc92 507 SUPERFAMILY SSF46689 455 503 3.99E-7 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS14110 73fa79135bf20c9fedbec7fb1bb7dc92 507 Gene3D G3DSA:1.10.8.60 372 441 1.0E-20 T 13-09-2016 THL1_RS14110 73fa79135bf20c9fedbec7fb1bb7dc92 507 Pfam PF00158 Sigma-54 interaction domain 199 365 1.0E-65 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS14110 73fa79135bf20c9fedbec7fb1bb7dc92 507 SUPERFAMILY SSF55785 79 164 4.0E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS14110 73fa79135bf20c9fedbec7fb1bb7dc92 507 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 412 421 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS14110 73fa79135bf20c9fedbec7fb1bb7dc92 507 Gene3D G3DSA:3.40.50.300 195 371 7.8E-57 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14110 73fa79135bf20c9fedbec7fb1bb7dc92 507 Pfam PF13188 PAS domain 81 127 1.0E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS01855 bb05f24144cc0317190341a9213f107e 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 3.1E-12 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS01855 bb05f24144cc0317190341a9213f107e 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 3.1E-12 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS01855 bb05f24144cc0317190341a9213f107e 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 3.1E-12 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS01855 bb05f24144cc0317190341a9213f107e 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 202 4.6E-22 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS01855 bb05f24144cc0317190341a9213f107e 210 SUPERFAMILY SSF52172 2 128 5.41E-30 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS01855 bb05f24144cc0317190341a9213f107e 210 Gene3D G3DSA:1.10.10.10 152 205 2.6E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS01855 bb05f24144cc0317190341a9213f107e 210 SMART SM00421 145 202 2.2E-21 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS01855 bb05f24144cc0317190341a9213f107e 210 PANTHER PTHR26402:SF151 2 204 9.3E-59 T 13-09-2016 THL1_RS01855 bb05f24144cc0317190341a9213f107e 210 Gene3D G3DSA:3.40.50.2300 2 151 1.0E-31 T 13-09-2016 THL1_RS01855 bb05f24144cc0317190341a9213f107e 210 SUPERFAMILY SSF46894 142 205 4.76E-19 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS01855 bb05f24144cc0317190341a9213f107e 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS01855 bb05f24144cc0317190341a9213f107e 210 Pfam PF00072 Response regulator receiver domain 4 114 4.6E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS01855 bb05f24144cc0317190341a9213f107e 210 PANTHER PTHR26402 2 204 9.3E-59 T 13-09-2016 THL1_RS01855 bb05f24144cc0317190341a9213f107e 210 SMART SM00448 2 114 5.4E-27 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS20590 9c3216a6884069e3e4c2b3ed35dda02e 248 PANTHER PTHR24321:SF6 2 247 8.8E-53 T 13-09-2016 THL1_RS20590 9c3216a6884069e3e4c2b3ed35dda02e 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS20590 9c3216a6884069e3e4c2b3ed35dda02e 248 SUPERFAMILY SSF51735 6 247 2.29E-81 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20590 9c3216a6884069e3e4c2b3ed35dda02e 248 Gene3D G3DSA:3.40.50.720 2 247 7.9E-83 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20590 9c3216a6884069e3e4c2b3ed35dda02e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.3E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20590 9c3216a6884069e3e4c2b3ed35dda02e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.3E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20590 9c3216a6884069e3e4c2b3ed35dda02e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.3E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20590 9c3216a6884069e3e4c2b3ed35dda02e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.3E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20590 9c3216a6884069e3e4c2b3ed35dda02e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.3E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20590 9c3216a6884069e3e4c2b3ed35dda02e 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 3.3E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20590 9c3216a6884069e3e4c2b3ed35dda02e 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 245 8.1E-67 T 13-09-2016 THL1_RS20590 9c3216a6884069e3e4c2b3ed35dda02e 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.5E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20590 9c3216a6884069e3e4c2b3ed35dda02e 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.5E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20590 9c3216a6884069e3e4c2b3ed35dda02e 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.5E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20590 9c3216a6884069e3e4c2b3ed35dda02e 248 PANTHER PTHR24321 2 247 8.8E-53 T 13-09-2016 THL1_RS25690 6a480df0abde350c44c6de03ea95f420 304 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 288 2.1E-50 T 13-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 THL1_RS25690 6a480df0abde350c44c6de03ea95f420 304 PANTHER PTHR11795 4 304 6.9E-133 T 13-09-2016 THL1_RS25690 6a480df0abde350c44c6de03ea95f420 304 PANTHER PTHR11795:SF371 4 304 6.9E-133 T 13-09-2016 THL1_RS18235 83a1dfe115290dcec322c3cecbf7ad08 185 SMART SM00855 33 155 0.0018 T 13-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 THL1_RS18235 83a1dfe115290dcec322c3cecbf7ad08 185 Gene3D G3DSA:3.40.50.1240 36 156 5.5E-12 T 13-09-2016 IPR029033 Histidine phosphatase superfamily THL1_RS18235 83a1dfe115290dcec322c3cecbf7ad08 185 SUPERFAMILY SSF53254 36 158 7.72E-15 T 13-09-2016 IPR029033 Histidine phosphatase superfamily THL1_RS18235 83a1dfe115290dcec322c3cecbf7ad08 185 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 57 103 1.2E-5 T 13-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 THL1_RS05245 83c5991d525d3462a11ad97f5ce342fb 533 Gene3D G3DSA:3.90.76.10 36 216 1.5E-48 T 13-09-2016 THL1_RS05245 83c5991d525d3462a11ad97f5ce342fb 533 PANTHER PTHR30290 22 531 2.4E-210 T 13-09-2016 THL1_RS05245 83c5991d525d3462a11ad97f5ce342fb 533 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 450 1.5E-98 T 13-09-2016 IPR000914 Solute-binding protein family 5 domain THL1_RS05245 83c5991d525d3462a11ad97f5ce342fb 533 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 76 98 - T 13-09-2016 IPR023765 Solute-binding protein family 5, conserved site THL1_RS05245 83c5991d525d3462a11ad97f5ce342fb 533 SUPERFAMILY SSF53850 28 530 1.21E-149 T 13-09-2016 THL1_RS05245 83c5991d525d3462a11ad97f5ce342fb 533 Gene3D G3DSA:3.10.105.10 287 502 3.2E-67 T 13-09-2016 THL1_RS05245 83c5991d525d3462a11ad97f5ce342fb 533 PANTHER PTHR30290:SF14 22 531 2.4E-210 T 13-09-2016 THL1_RS05245 83c5991d525d3462a11ad97f5ce342fb 533 PIRSF PIRSF002741 5 528 2.0E-118 T 13-09-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 Gene3D G3DSA:2.40.30.10 288 378 3.8E-18 T 13-09-2016 THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 PANTHER PTHR23115:SF98 7 189 3.1E-189 T 13-09-2016 THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 PANTHER PTHR23115:SF98 283 674 3.1E-189 T 13-09-2016 THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 PANTHER PTHR23115:SF98 233 261 3.1E-189 T 13-09-2016 THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 Gene3D G3DSA:3.30.230.10 466 581 2.1E-45 T 13-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 Gene3D G3DSA:3.30.70.240 582 668 2.3E-22 T 13-09-2016 IPR000640 Translation elongation factor EFG, V domain THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 SUPERFAMILY SSF52540 5 260 1.51E-67 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 148 7.9E-15 T 13-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 SUPERFAMILY SSF50447 243 378 1.45E-21 T 13-09-2016 IPR009000 Translation protein, beta-barrel domain THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 SUPERFAMILY SSF54980 386 464 2.3E-16 T 13-09-2016 IPR009022 Elongation factor G, III-V domain THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 Pfam PF00009 Elongation factor Tu GTP binding domain 8 259 1.6E-36 T 13-09-2016 THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 Gene3D G3DSA:3.40.50.300 5 264 3.0E-56 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 PRINTS PR00315 GTP-binding elongation factor signature 11 24 9.9E-5 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 PRINTS PR00315 GTP-binding elongation factor signature 77 87 9.9E-5 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 PRINTS PR00315 GTP-binding elongation factor signature 129 138 9.9E-5 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 Pfam PF00679 Elongation factor G C-terminus 583 669 4.1E-24 T 13-09-2016 IPR000640 Translation elongation factor EFG, V domain THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 PANTHER PTHR23115 7 189 3.1E-189 T 13-09-2016 THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 PANTHER PTHR23115 283 674 3.1E-189 T 13-09-2016 THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 PANTHER PTHR23115 233 261 3.1E-189 T 13-09-2016 THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 SMART SM00838 582 670 1.4E-28 T 13-09-2016 IPR000640 Translation elongation factor EFG, V domain THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 Gene3D G3DSA:3.30.70.870 386 462 9.4E-23 T 13-09-2016 THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 SUPERFAMILY SSF54211 461 580 9.36E-40 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 SMART SM00889 462 580 1.8E-58 T 13-09-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 Pfam PF14492 Elongation Factor G, domain II 386 459 5.4E-20 T 13-09-2016 IPR009022 Elongation factor G, III-V domain THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 Pfam PF03764 Elongation factor G, domain IV 461 579 1.0E-39 T 13-09-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THL1_RS01905 cce64bab31d5e32e52f93ceaa67a6731 681 SUPERFAMILY SSF54980 585 677 1.01E-21 T 13-09-2016 IPR009022 Elongation factor G, III-V domain THL1_RS19110 ee1daf6a73e763f8816b6067f05c1ac3 222 Pfam PF08239 Bacterial SH3 domain 52 101 1.3E-8 T 13-09-2016 IPR003646 SH3-like domain, bacterial-type THL1_RS19110 ee1daf6a73e763f8816b6067f05c1ac3 222 TIGRFAM TIGR04211 SH3_and_anchor: SH3 domain protein 45 221 2.4E-43 T 13-09-2016 IPR016476 SH3 domain protein THL1_RS19110 ee1daf6a73e763f8816b6067f05c1ac3 222 PIRSF PIRSF006158 15 222 2.1E-70 T 13-09-2016 IPR016476 SH3 domain protein THL1_RS19110 ee1daf6a73e763f8816b6067f05c1ac3 222 SMART SM00287 41 104 6.4E-6 T 13-09-2016 IPR003646 SH3-like domain, bacterial-type THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 Pfam PF00072 Response regulator receiver domain 653 764 6.2E-28 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 SMART SM00388 291 356 1.1E-22 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 SUPERFAMILY SSF52172 649 769 2.28E-43 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 402 511 4.2E-26 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 SMART SM00387 402 513 7.2E-38 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 Gene3D G3DSA:3.40.50.2300 639 769 1.3E-48 T 13-09-2016 THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 Gene3D G3DSA:1.10.287.130 286 352 1.7E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 SMART SM00448 651 764 3.7E-41 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 SUPERFAMILY SSF47384 275 357 3.53E-19 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 PANTHER PTHR24423 634 768 1.8E-151 T 13-09-2016 THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 PANTHER PTHR24423 287 516 1.8E-151 T 13-09-2016 THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 PANTHER PTHR24423 238 254 1.8E-151 T 13-09-2016 THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 491 4.3E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 PRINTS PR00344 Bacterial sensor protein C-terminal signature 497 510 4.3E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 452 4.3E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 466 4.3E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 Pfam PF00512 His Kinase A (phospho-acceptor) domain 292 356 2.7E-17 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 SUPERFAMILY SSF55874 345 515 7.2E-47 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS11605 5fd791718c9fcc0811b212d86d116110 774 Gene3D G3DSA:3.30.565.10 357 517 2.7E-45 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS10565 da98a35e2e5badce483dba9d11fc3ca7 308 Gene3D G3DSA:3.40.50.2300 179 306 2.9E-26 T 13-09-2016 THL1_RS10565 da98a35e2e5badce483dba9d11fc3ca7 308 Gene3D G3DSA:2.40.50.180 61 95 6.7E-7 T 13-09-2016 THL1_RS10565 da98a35e2e5badce483dba9d11fc3ca7 308 Pfam PF00072 Response regulator receiver domain 181 299 8.5E-16 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS10565 da98a35e2e5badce483dba9d11fc3ca7 308 PANTHER PTHR22617:SF30 1 170 1.2E-73 T 13-09-2016 THL1_RS10565 da98a35e2e5badce483dba9d11fc3ca7 308 Gene3D G3DSA:2.30.30.40 96 144 2.6E-6 T 13-09-2016 THL1_RS10565 da98a35e2e5badce483dba9d11fc3ca7 308 SUPERFAMILY SSF52172 180 306 1.71E-23 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS10565 da98a35e2e5badce483dba9d11fc3ca7 308 SMART SM00448 179 300 3.0E-16 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS10565 da98a35e2e5badce483dba9d11fc3ca7 308 PIRSF PIRSF002867 1 308 3.1E-106 T 13-09-2016 IPR024181 Chemotaxis response regulator CheV THL1_RS10565 da98a35e2e5badce483dba9d11fc3ca7 308 PANTHER PTHR22617 1 170 1.2E-73 T 13-09-2016 THL1_RS10565 da98a35e2e5badce483dba9d11fc3ca7 308 SUPERFAMILY SSF50341 16 157 1.57E-38 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS10565 da98a35e2e5badce483dba9d11fc3ca7 308 Pfam PF01584 CheW-like domain 21 155 3.2E-38 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS10565 da98a35e2e5badce483dba9d11fc3ca7 308 SMART SM00260 17 153 4.3E-25 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS15645 747c9dc6c5cb42fff6991fed4450b3b7 505 SUPERFAMILY SSF46626 98 175 1.46E-37 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS15645 747c9dc6c5cb42fff6991fed4450b3b7 505 Gene3D G3DSA:2.60.40.10 295 373 1.2E-27 T 13-09-2016 IPR013783 Immunoglobulin-like fold THL1_RS15645 747c9dc6c5cb42fff6991fed4450b3b7 505 Pfam PF09100 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV 379 504 8.3E-51 T 13-09-2016 IPR015184 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV THL1_RS15645 747c9dc6c5cb42fff6991fed4450b3b7 505 Gene3D G3DSA:1.10.760.10 12 79 4.8E-4 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS15645 747c9dc6c5cb42fff6991fed4450b3b7 505 Gene3D G3DSA:2.40.128.120 187 293 5.0E-44 T 13-09-2016 IPR009111 Quinohemoprotein amine dehydrogenase, alpha subunit, domain 2 THL1_RS15645 747c9dc6c5cb42fff6991fed4450b3b7 505 SUPERFAMILY SSF69298 175 291 4.71E-42 T 13-09-2016 IPR009111 Quinohemoprotein amine dehydrogenase, alpha subunit, domain 2 THL1_RS15645 747c9dc6c5cb42fff6991fed4450b3b7 505 SUPERFAMILY SSF81296 295 373 4.27E-19 T 13-09-2016 IPR014756 Immunoglobulin E-set THL1_RS15645 747c9dc6c5cb42fff6991fed4450b3b7 505 TIGRFAM TIGR03908 QH_alpha: quinohemoprotein amine dehydrogenase, alpha subunit 9 504 8.1E-212 T 13-09-2016 IPR023887 Quinohemoprotein amine dehydrogenase, alpha subunit THL1_RS15645 747c9dc6c5cb42fff6991fed4450b3b7 505 Pfam PF14930 Quinohemoprotein amine dehydrogenase, alpha subunit domain II 189 291 3.0E-40 T 13-09-2016 IPR009111 Quinohemoprotein amine dehydrogenase, alpha subunit, domain 2 THL1_RS15645 747c9dc6c5cb42fff6991fed4450b3b7 505 SUPERFAMILY SSF46626 13 95 5.87E-18 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS15645 747c9dc6c5cb42fff6991fed4450b3b7 505 Gene3D G3DSA:2.60.40.10 376 497 9.3E-57 T 13-09-2016 IPR013783 Immunoglobulin-like fold THL1_RS15645 747c9dc6c5cb42fff6991fed4450b3b7 505 Pfam PF09098 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding 15 178 8.3E-73 T 13-09-2016 IPR015182 Quinohemoprotein amine dehydrogenase, alpha subunit, haem binding domain THL1_RS15645 747c9dc6c5cb42fff6991fed4450b3b7 505 SUPERFAMILY SSF81296 376 505 2.59E-55 T 13-09-2016 IPR014756 Immunoglobulin E-set THL1_RS15645 747c9dc6c5cb42fff6991fed4450b3b7 505 Pfam PF09099 Quinohemoprotein amine dehydrogenase, alpha subunit domain III 295 374 5.9E-24 T 13-09-2016 IPR015183 Quinohemoprotein amine dehydrogenase, alpha subunit domain III THL1_RS01620 d9d05ee80540826bf5166cecfc5573c5 556 PANTHER PTHR23389:SF7 20 492 1.7E-139 T 13-09-2016 THL1_RS01620 d9d05ee80540826bf5166cecfc5573c5 556 Gene3D G3DSA:1.10.287.610 25 75 2.5E-5 T 13-09-2016 THL1_RS01620 d9d05ee80540826bf5166cecfc5573c5 556 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 28 306 2.2E-23 T 13-09-2016 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 THL1_RS01620 d9d05ee80540826bf5166cecfc5573c5 556 Gene3D G3DSA:1.10.150.20 481 549 5.2E-6 T 13-09-2016 THL1_RS01620 d9d05ee80540826bf5166cecfc5573c5 556 SUPERFAMILY SSF47781 392 550 4.7E-24 T 13-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 THL1_RS01620 d9d05ee80540826bf5166cecfc5573c5 556 Gene3D G3DSA:3.30.470.30 128 244 2.4E-14 T 13-09-2016 THL1_RS01620 d9d05ee80540826bf5166cecfc5573c5 556 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 321 336 - T 13-09-2016 IPR033136 NAD-dependent DNA ligase, conserved site THL1_RS01620 d9d05ee80540826bf5166cecfc5573c5 556 SUPERFAMILY SSF56091 23 306 2.3E-64 T 13-09-2016 THL1_RS01620 d9d05ee80540826bf5166cecfc5573c5 556 SUPERFAMILY SSF50249 310 385 1.88E-18 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS01620 d9d05ee80540826bf5166cecfc5573c5 556 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 312 384 2.8E-20 T 13-09-2016 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 THL1_RS01620 d9d05ee80540826bf5166cecfc5573c5 556 PANTHER PTHR23389 20 492 1.7E-139 T 13-09-2016 THL1_RS01620 d9d05ee80540826bf5166cecfc5573c5 556 Gene3D G3DSA:2.40.50.140 310 381 1.1E-20 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS01620 d9d05ee80540826bf5166cecfc5573c5 556 SMART SM00532 27 426 7.2E-41 T 13-09-2016 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 THL1_RS01620 d9d05ee80540826bf5166cecfc5573c5 556 Hamap MF_01587 DNA ligase B [ligB]. 3 552 51.284 T 13-09-2016 IPR020923 DNA ligase B GO:0003911|GO:0006259 THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 Gene3D G3DSA:1.10.287.130 456 525 7.4E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 Pfam PF00072 Response regulator receiver domain 715 826 2.2E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 Gene3D G3DSA:3.40.50.2300 710 829 6.6E-37 T 13-09-2016 THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 Gene3D G3DSA:3.30.565.10 530 695 7.7E-42 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 SUPERFAMILY SSF55785 317 367 7.95E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 SMART SM00387 576 692 8.6E-36 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 Gene3D G3DSA:3.30.450.20 317 442 4.9E-8 T 13-09-2016 THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 Pfam PF03924 CHASE domain 127 243 7.2E-16 T 13-09-2016 IPR006189 CHASE domain THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 SMART SM01079 64 245 1.2E-36 T 13-09-2016 IPR006189 CHASE domain THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 576 691 3.4E-23 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 PRINTS PR00344 Bacterial sensor protein C-terminal signature 635 645 3.9E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 PRINTS PR00344 Bacterial sensor protein C-terminal signature 676 689 3.9E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 PRINTS PR00344 Bacterial sensor protein C-terminal signature 652 670 3.9E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 PRINTS PR00344 Bacterial sensor protein C-terminal signature 617 631 3.9E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 SUPERFAMILY SSF55874 518 690 1.23E-41 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 Pfam PF00512 His Kinase A (phospho-acceptor) domain 463 529 4.7E-15 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 SUPERFAMILY SSF52172 712 830 1.27E-36 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 SUPERFAMILY SSF47384 448 530 3.34E-18 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 SMART SM00388 463 529 1.2E-17 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 PANTHER PTHR24423 22 31 1.9E-136 T 13-09-2016 THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 PANTHER PTHR24423 324 828 1.9E-136 T 13-09-2016 THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 PANTHER PTHR24423 147 166 1.9E-136 T 13-09-2016 THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 Pfam PF12860 PAS fold 332 446 5.9E-14 T 13-09-2016 THL1_RS06110 65d9e227c76b5817fc4956811dddb7dd 843 SMART SM00448 713 826 3.9E-35 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 Gene3D G3DSA:3.20.20.450 568 818 2.1E-95 T 13-09-2016 IPR001633 EAL domain THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 259 384 1.3E-21 T 13-09-2016 IPR000014 PAS domain THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 SMART SM00267 378 555 4.6E-58 T 13-09-2016 IPR000160 GGDEF domain THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 Gene3D G3DSA:3.30.70.270 391 561 4.0E-55 T 13-09-2016 THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 PANTHER PTHR10799 146 298 1.1E-77 T 13-09-2016 THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 PANTHER PTHR10799 422 666 1.1E-77 T 13-09-2016 THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 SUPERFAMILY SSF141868 571 818 2.09E-89 T 13-09-2016 IPR001633 EAL domain THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 SMART SM00052 565 811 2.8E-114 T 13-09-2016 IPR001633 EAL domain THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 SMART SM00091 266 331 2.4E-10 T 13-09-2016 IPR000014 PAS domain THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 387 554 8.8E-44 T 13-09-2016 IPR000160 GGDEF domain THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 Gene3D G3DSA:3.30.450.20 257 376 3.0E-24 T 13-09-2016 THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 PANTHER PTHR10799:SF774 146 298 1.1E-77 T 13-09-2016 THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 PANTHER PTHR10799:SF774 422 666 1.1E-77 T 13-09-2016 THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 Pfam PF00990 Diguanylate cyclase, GGDEF domain 389 551 6.6E-48 T 13-09-2016 IPR000160 GGDEF domain THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 Pfam PF13426 PAS domain 277 376 5.3E-14 T 13-09-2016 IPR000014 PAS domain THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 SUPERFAMILY SSF55785 277 387 2.42E-23 T 13-09-2016 IPR000014 PAS domain THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 SUPERFAMILY SSF55073 394 557 1.28E-48 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 SMART SM00086 336 378 5.8E-9 T 13-09-2016 IPR001610 PAC motif THL1_RS07210 45018b5a3e8d8199fde2f4d6edf36715 824 Pfam PF00563 EAL domain 571 806 1.9E-70 T 13-09-2016 IPR001633 EAL domain THL1_RS01830 617a4065a9cc3728fdfd1eef2cdd23e6 333 Gene3D G3DSA:1.10.10.60 264 312 1.2E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01830 617a4065a9cc3728fdfd1eef2cdd23e6 333 PANTHER PTHR11019:SF90 1 26 2.0E-135 T 13-09-2016 THL1_RS01830 617a4065a9cc3728fdfd1eef2cdd23e6 333 Gene3D G3DSA:1.10.10.60 209 263 2.9E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01830 617a4065a9cc3728fdfd1eef2cdd23e6 333 Pfam PF01965 DJ-1/PfpI family 21 170 1.6E-9 T 13-09-2016 IPR002818 DJ-1/PfpI THL1_RS01830 617a4065a9cc3728fdfd1eef2cdd23e6 333 PANTHER PTHR11019 51 317 2.0E-135 T 13-09-2016 THL1_RS01830 617a4065a9cc3728fdfd1eef2cdd23e6 333 SUPERFAMILY SSF46689 262 312 2.24E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01830 617a4065a9cc3728fdfd1eef2cdd23e6 333 SUPERFAMILY SSF52317 5 190 2.34E-39 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS01830 617a4065a9cc3728fdfd1eef2cdd23e6 333 PANTHER PTHR11019:SF90 51 317 2.0E-135 T 13-09-2016 THL1_RS01830 617a4065a9cc3728fdfd1eef2cdd23e6 333 Pfam PF12833 Helix-turn-helix domain 232 309 2.5E-23 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS01830 617a4065a9cc3728fdfd1eef2cdd23e6 333 Gene3D G3DSA:3.40.50.880 5 201 2.7E-31 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS01830 617a4065a9cc3728fdfd1eef2cdd23e6 333 SMART SM00342 226 309 6.2E-26 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS01830 617a4065a9cc3728fdfd1eef2cdd23e6 333 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 278 293 4.8E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS01830 617a4065a9cc3728fdfd1eef2cdd23e6 333 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 293 309 4.8E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS01830 617a4065a9cc3728fdfd1eef2cdd23e6 333 PANTHER PTHR11019 1 26 2.0E-135 T 13-09-2016 THL1_RS08510 4fa9476cd374d09f37eef8558cc1d5b1 537 PANTHER PTHR11938 159 529 2.7E-98 T 13-09-2016 THL1_RS08510 4fa9476cd374d09f37eef8558cc1d5b1 537 PIRSF PIRSF006429 11 536 4.2E-162 T 13-09-2016 IPR024188 Glutamate synthase large subunit-like protein THL1_RS08510 4fa9476cd374d09f37eef8558cc1d5b1 537 SUPERFAMILY SSF51395 17 500 7.33E-135 T 13-09-2016 THL1_RS08510 4fa9476cd374d09f37eef8558cc1d5b1 537 PIRSF PIRSF500060 12 531 1.3E-240 T 13-09-2016 IPR027283 Glutamate synthase large subunit-like protein, bacteria THL1_RS08510 4fa9476cd374d09f37eef8558cc1d5b1 537 Gene3D G3DSA:3.20.20.70 49 508 8.5E-123 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS08510 4fa9476cd374d09f37eef8558cc1d5b1 537 Pfam PF01645 Conserved region in glutamate synthase 157 474 2.4E-80 T 13-09-2016 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 THL1_RS08510 4fa9476cd374d09f37eef8558cc1d5b1 537 PANTHER PTHR11938:SF50 159 529 2.7E-98 T 13-09-2016 THL1_RS21605 9241deb5f13bd4845d513a3be42aa2a1 702 Gene3D G3DSA:3.40.50.740 365 485 1.7E-49 T 13-09-2016 THL1_RS21605 9241deb5f13bd4845d513a3be42aa2a1 702 Gene3D G3DSA:3.40.50.740 67 123 1.7E-49 T 13-09-2016 THL1_RS21605 9241deb5f13bd4845d513a3be42aa2a1 702 PANTHER PTHR11615 9 699 5.8E-234 T 13-09-2016 THL1_RS21605 9241deb5f13bd4845d513a3be42aa2a1 702 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 9 59 3.5E-5 T 13-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 THL1_RS21605 9241deb5f13bd4845d513a3be42aa2a1 702 Pfam PF01568 Molydopterin dinucleotide binding domain 576 695 8.4E-26 T 13-09-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 THL1_RS21605 9241deb5f13bd4845d513a3be42aa2a1 702 PANTHER PTHR11615:SF125 9 699 5.8E-234 T 13-09-2016 THL1_RS21605 9241deb5f13bd4845d513a3be42aa2a1 702 Gene3D G3DSA:2.40.40.20 571 700 1.4E-28 T 13-09-2016 THL1_RS21605 9241deb5f13bd4845d513a3be42aa2a1 702 SUPERFAMILY SSF53706 6 621 7.2E-129 T 13-09-2016 THL1_RS21605 9241deb5f13bd4845d513a3be42aa2a1 702 Gene3D G3DSA:3.40.228.10 150 346 4.9E-47 T 13-09-2016 THL1_RS21605 9241deb5f13bd4845d513a3be42aa2a1 702 Pfam PF00384 Molybdopterin oxidoreductase 65 483 2.1E-38 T 13-09-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 THL1_RS21605 9241deb5f13bd4845d513a3be42aa2a1 702 SMART SM00926 3 62 8.6E-12 T 13-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 THL1_RS21605 9241deb5f13bd4845d513a3be42aa2a1 702 Gene3D G3DSA:2.20.25.90 4 66 6.0E-14 T 13-09-2016 THL1_RS27845 0599253fa0fe1cdbe258f6986d5c5806 147 PIRSF PIRSF003230 2 143 7.0E-25 T 13-09-2016 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 THL1_RS27845 0599253fa0fe1cdbe258f6986d5c5806 147 PANTHER PTHR31793:SF9 10 142 3.1E-34 T 13-09-2016 THL1_RS27845 0599253fa0fe1cdbe258f6986d5c5806 147 PANTHER PTHR31793 10 142 3.1E-34 T 13-09-2016 THL1_RS27845 0599253fa0fe1cdbe258f6986d5c5806 147 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 14 129 7.7E-26 T 13-09-2016 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 THL1_RS27845 0599253fa0fe1cdbe258f6986d5c5806 147 SUPERFAMILY SSF54637 7 140 1.87E-40 T 13-09-2016 IPR029069 HotDog domain THL1_RS27845 0599253fa0fe1cdbe258f6986d5c5806 147 Pfam PF03061 Thioesterase superfamily 25 109 7.6E-16 T 13-09-2016 IPR006683 Thioesterase domain THL1_RS27845 0599253fa0fe1cdbe258f6986d5c5806 147 Gene3D G3DSA:3.10.129.10 4 140 3.6E-43 T 13-09-2016 IPR029069 HotDog domain THL1_RS09080 0c86a6ec9a65dd1861095aaab8154303 401 Gene3D G3DSA:1.20.1250.20 212 393 2.8E-20 T 13-09-2016 THL1_RS09080 0c86a6ec9a65dd1861095aaab8154303 401 Gene3D G3DSA:1.20.1250.20 10 195 2.4E-20 T 13-09-2016 THL1_RS09080 0c86a6ec9a65dd1861095aaab8154303 401 Pfam PF07690 Major Facilitator Superfamily 17 315 1.5E-28 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS09080 0c86a6ec9a65dd1861095aaab8154303 401 PANTHER PTHR11360 4 396 3.0E-154 T 13-09-2016 THL1_RS09080 0c86a6ec9a65dd1861095aaab8154303 401 PANTHER PTHR11360:SF115 4 396 3.0E-154 T 13-09-2016 THL1_RS09080 0c86a6ec9a65dd1861095aaab8154303 401 SUPERFAMILY SSF103473 5 389 1.44E-55 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS03800 f3dfd20f3485eab0d27c1278e0c37269 420 Pfam PF12704 MacB-like periplasmic core domain 19 202 5.4E-12 T 13-09-2016 IPR025857 MacB-like periplasmic core domain THL1_RS03800 f3dfd20f3485eab0d27c1278e0c37269 420 PANTHER PTHR30489 227 419 1.3E-115 T 13-09-2016 THL1_RS03800 f3dfd20f3485eab0d27c1278e0c37269 420 PANTHER PTHR30489 1 203 1.3E-115 T 13-09-2016 THL1_RS03800 f3dfd20f3485eab0d27c1278e0c37269 420 Pfam PF02687 FtsX-like permease family 293 411 2.2E-20 T 13-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 THL1_RS03800 f3dfd20f3485eab0d27c1278e0c37269 420 PANTHER PTHR30489:SF2 227 419 1.3E-115 T 13-09-2016 THL1_RS03800 f3dfd20f3485eab0d27c1278e0c37269 420 PANTHER PTHR30489:SF2 1 203 1.3E-115 T 13-09-2016 THL1_RS21680 e8cc28ac67c8fee32df4606ff461bf1e 303 Gene3D G3DSA:3.40.190.10 93 191 1.4E-15 T 13-09-2016 THL1_RS21680 e8cc28ac67c8fee32df4606ff461bf1e 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 4.6E-15 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS21680 e8cc28ac67c8fee32df4606ff461bf1e 303 PANTHER PTHR30126 7 295 2.6E-89 T 13-09-2016 THL1_RS21680 e8cc28ac67c8fee32df4606ff461bf1e 303 PANTHER PTHR30126:SF16 7 295 2.6E-89 T 13-09-2016 THL1_RS21680 e8cc28ac67c8fee32df4606ff461bf1e 303 SUPERFAMILY SSF46785 8 86 2.25E-16 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS21680 e8cc28ac67c8fee32df4606ff461bf1e 303 SUPERFAMILY SSF53850 95 298 1.27E-25 T 13-09-2016 THL1_RS21680 e8cc28ac67c8fee32df4606ff461bf1e 303 Gene3D G3DSA:1.10.10.10 6 84 2.0E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS21680 e8cc28ac67c8fee32df4606ff461bf1e 303 Pfam PF03466 LysR substrate binding domain 93 294 3.3E-26 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS07230 d2a58b82b393b10d58e19837a43c7447 70 PANTHER PTHR14119 1 54 4.3E-34 T 13-09-2016 THL1_RS07230 d2a58b82b393b10d58e19837a43c7447 70 PANTHER PTHR14119:SF10 1 54 4.3E-34 T 13-09-2016 THL1_RS07230 d2a58b82b393b10d58e19837a43c7447 70 Gene3D G3DSA:3.40.50.850 2 56 8.0E-5 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS24880 6821b2716f079d1857bf4df4de3aa944 481 PANTHER PTHR11819 1 470 4.5E-97 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS24880 6821b2716f079d1857bf4df4de3aa944 481 Pfam PF00474 Sodium:solute symporter family 32 426 4.4E-39 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS24880 6821b2716f079d1857bf4df4de3aa944 481 PANTHER PTHR11819:SF141 1 470 4.5E-97 T 13-09-2016 THL1_RS27970 ced1a23b429e150d1bd84b6b6fd9767c 55 Gene3D G3DSA:2.20.28.10 1 54 1.0E-26 T 13-09-2016 IPR004039 Rubredoxin-type fold THL1_RS27970 ced1a23b429e150d1bd84b6b6fd9767c 55 PRINTS PR00163 Rubredoxin signature 3 19 2.2E-8 T 13-09-2016 IPR024935 Rubredoxin domain GO:0005506 THL1_RS27970 ced1a23b429e150d1bd84b6b6fd9767c 55 PRINTS PR00163 Rubredoxin signature 33 49 2.2E-8 T 13-09-2016 IPR024935 Rubredoxin domain GO:0005506 THL1_RS27970 ced1a23b429e150d1bd84b6b6fd9767c 55 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 13-09-2016 IPR018527 Rubredoxin, iron-binding site GO:0046872 THL1_RS27970 ced1a23b429e150d1bd84b6b6fd9767c 55 SUPERFAMILY SSF57802 1 54 2.86E-22 T 13-09-2016 THL1_RS27970 ced1a23b429e150d1bd84b6b6fd9767c 55 Pfam PF00301 Rubredoxin 3 49 1.1E-22 T 13-09-2016 IPR024935 Rubredoxin domain GO:0005506 THL1_RS27970 ced1a23b429e150d1bd84b6b6fd9767c 55 PIRSF PIRSF000071 1 55 4.0E-24 T 13-09-2016 IPR024922 Rubredoxin GO:0005506|GO:0009055 THL1_RS07075 7243b82da6054dadce2b8b85b8ac6bc2 350 PANTHER PTHR10909 1 344 1.4E-43 T 13-09-2016 THL1_RS07075 7243b82da6054dadce2b8b85b8ac6bc2 350 SUPERFAMILY SSF56645 1 128 6.54E-20 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS07075 7243b82da6054dadce2b8b85b8ac6bc2 350 Gene3D G3DSA:1.10.540.10 1 120 4.4E-18 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS07075 7243b82da6054dadce2b8b85b8ac6bc2 350 SUPERFAMILY SSF47203 190 338 9.99E-35 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS07075 7243b82da6054dadce2b8b85b8ac6bc2 350 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.3E-13 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS07075 7243b82da6054dadce2b8b85b8ac6bc2 350 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 198 335 1.1E-22 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS07075 7243b82da6054dadce2b8b85b8ac6bc2 350 PANTHER PTHR10909:SF302 1 344 1.4E-43 T 13-09-2016 THL1_RS07075 7243b82da6054dadce2b8b85b8ac6bc2 350 Gene3D G3DSA:1.20.140.10 197 338 5.6E-30 T 13-09-2016 THL1_RS03240 50efbbff95ca1329a46f35927208f687 114 PANTHER PTHR30203:SF5 1 108 8.4E-25 T 13-09-2016 THL1_RS03240 50efbbff95ca1329a46f35927208f687 114 Gene3D G3DSA:1.20.1600.10 1 107 9.3E-20 T 13-09-2016 THL1_RS03240 50efbbff95ca1329a46f35927208f687 114 PANTHER PTHR30203 1 108 8.4E-25 T 13-09-2016 THL1_RS03240 50efbbff95ca1329a46f35927208f687 114 Pfam PF02321 Outer membrane efflux protein 1 104 7.8E-9 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS03240 50efbbff95ca1329a46f35927208f687 114 SUPERFAMILY SSF56954 1 110 6.41E-20 T 13-09-2016 THL1_RS21900 027707c8c4d184ec692b2d41469a4d56 302 Pfam PF00561 alpha/beta hydrolase fold 32 136 3.6E-18 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS21900 027707c8c4d184ec692b2d41469a4d56 302 Gene3D G3DSA:3.40.50.1820 8 295 1.4E-52 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS21900 027707c8c4d184ec692b2d41469a4d56 302 PRINTS PR00412 Epoxide hydrolase signature 239 255 1.6E-6 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS21900 027707c8c4d184ec692b2d41469a4d56 302 PRINTS PR00412 Epoxide hydrolase signature 104 117 1.6E-6 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS21900 027707c8c4d184ec692b2d41469a4d56 302 PRINTS PR00412 Epoxide hydrolase signature 38 56 1.6E-6 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS21900 027707c8c4d184ec692b2d41469a4d56 302 PRINTS PR00412 Epoxide hydrolase signature 271 293 1.6E-6 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS21900 027707c8c4d184ec692b2d41469a4d56 302 PANTHER PTHR10992 153 296 6.9E-30 T 13-09-2016 THL1_RS21900 027707c8c4d184ec692b2d41469a4d56 302 PANTHER PTHR10992 17 120 6.9E-30 T 13-09-2016 THL1_RS21900 027707c8c4d184ec692b2d41469a4d56 302 SUPERFAMILY SSF53474 8 295 5.46E-48 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS28070 bf29609b97022779e0b59b2a0ab50488 227 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS28070 bf29609b97022779e0b59b2a0ab50488 227 PANTHER PTHR24220 3 224 6.3E-96 T 13-09-2016 THL1_RS28070 bf29609b97022779e0b59b2a0ab50488 227 SUPERFAMILY SSF52540 2 221 1.6E-68 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28070 bf29609b97022779e0b59b2a0ab50488 227 Gene3D G3DSA:3.40.50.300 4 220 1.4E-64 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28070 bf29609b97022779e0b59b2a0ab50488 227 Pfam PF00005 ABC transporter 21 169 9.8E-31 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS28070 bf29609b97022779e0b59b2a0ab50488 227 SMART SM00382 30 217 7.4E-10 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS28070 bf29609b97022779e0b59b2a0ab50488 227 PANTHER PTHR24220:SF578 3 224 6.3E-96 T 13-09-2016 THL1_RS16965 362533771ce67bda91425283ef32db72 366 Gene3D G3DSA:3.10.310.10 2 176 2.8E-77 T 13-09-2016 THL1_RS16965 362533771ce67bda91425283ef32db72 366 SUPERFAMILY SSF54506 171 360 2.04E-53 T 13-09-2016 THL1_RS16965 362533771ce67bda91425283ef32db72 366 SUPERFAMILY SSF54506 2 168 1.26E-64 T 13-09-2016 THL1_RS16965 362533771ce67bda91425283ef32db72 366 PANTHER PTHR30349 1 366 7.7E-53 T 13-09-2016 THL1_RS16965 362533771ce67bda91425283ef32db72 366 Pfam PF04303 PrpF protein 3 358 9.3E-124 T 13-09-2016 IPR007400 PrpF protein THL1_RS16965 362533771ce67bda91425283ef32db72 366 Gene3D G3DSA:3.10.310.10 177 337 6.3E-52 T 13-09-2016 THL1_RS16965 362533771ce67bda91425283ef32db72 366 PANTHER PTHR30349:SF39 1 366 7.7E-53 T 13-09-2016 THL1_RS04705 f852bbf4898ae9d9dcb83503a135ec92 136 PANTHER PTHR30266 1 136 4.0E-58 T 13-09-2016 THL1_RS04705 f852bbf4898ae9d9dcb83503a135ec92 136 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 3 134 29.693 T 13-09-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 THL1_RS04705 f852bbf4898ae9d9dcb83503a135ec92 136 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 3 131 9.2E-46 T 13-09-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 THL1_RS04705 f852bbf4898ae9d9dcb83503a135ec92 136 SUPERFAMILY SSF81330 13 127 6.28E-36 T 13-09-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 THL1_RS04705 f852bbf4898ae9d9dcb83503a135ec92 136 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 92 4.1E-13 T 13-09-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 THL1_RS04705 f852bbf4898ae9d9dcb83503a135ec92 136 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 6 20 4.1E-13 T 13-09-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 THL1_RS04705 f852bbf4898ae9d9dcb83503a135ec92 136 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 93 102 4.1E-13 T 13-09-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 THL1_RS04705 f852bbf4898ae9d9dcb83503a135ec92 136 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 4 133 7.1E-50 T 13-09-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 THL1_RS04705 f852bbf4898ae9d9dcb83503a135ec92 136 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 13 26 - T 13-09-2016 IPR019823 Large-conductance mechanosensitive channel, conserved site THL1_RS04705 f852bbf4898ae9d9dcb83503a135ec92 136 PANTHER PTHR30266:SF2 1 136 4.0E-58 T 13-09-2016 THL1_RS18105 d86abde58e185bb487d6c33fc1d0f611 403 PANTHER PTHR23515 1 395 9.3E-221 T 13-09-2016 THL1_RS18105 d86abde58e185bb487d6c33fc1d0f611 403 SUPERFAMILY SSF103473 6 386 5.1E-56 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS18105 d86abde58e185bb487d6c33fc1d0f611 403 Gene3D G3DSA:1.20.1250.20 12 194 2.6E-22 T 13-09-2016 THL1_RS18105 d86abde58e185bb487d6c33fc1d0f611 403 Gene3D G3DSA:1.20.1250.20 209 387 2.0E-19 T 13-09-2016 THL1_RS18105 d86abde58e185bb487d6c33fc1d0f611 403 TIGRFAM TIGR00886 2A0108: nitrite transporter 13 347 4.0E-95 T 13-09-2016 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 THL1_RS18105 d86abde58e185bb487d6c33fc1d0f611 403 Pfam PF07690 Major Facilitator Superfamily 23 348 1.9E-38 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS18105 d86abde58e185bb487d6c33fc1d0f611 403 PANTHER PTHR23515:SF4 1 395 9.3E-221 T 13-09-2016 THL1_RS27420 220e3ed956a5f420197a114dfd5e375d 163 Pfam PF02600 Disulfide bond formation protein DsbB 7 157 2.4E-42 T 13-09-2016 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 THL1_RS27420 220e3ed956a5f420197a114dfd5e375d 163 SUPERFAMILY SSF158442 10 158 2.35E-44 T 13-09-2016 THL1_RS27420 220e3ed956a5f420197a114dfd5e375d 163 Gene3D G3DSA:1.20.1550.10 3 162 2.7E-49 T 13-09-2016 IPR023380 Disulphide bond formation protein DsbB-like domain THL1_RS27420 220e3ed956a5f420197a114dfd5e375d 163 PANTHER PTHR36570 1 162 1.1E-51 T 13-09-2016 THL1_RS27420 220e3ed956a5f420197a114dfd5e375d 163 Hamap MF_00286 Disulfide bond formation protein B [dsbB]. 2 163 23.47 T 13-09-2016 IPR022920 Disulphide bond formation protein DsbB THL1_RS27420 220e3ed956a5f420197a114dfd5e375d 163 PANTHER PTHR36570:SF1 1 162 1.1E-51 T 13-09-2016 THL1_RS26850 bc6bec2f8bb31addbaf7ecf047d9d8cc 404 PANTHER PTHR13369:SF1 105 257 7.9E-84 T 13-09-2016 THL1_RS26850 bc6bec2f8bb31addbaf7ecf047d9d8cc 404 PANTHER PTHR13369 337 404 7.9E-84 T 13-09-2016 THL1_RS26850 bc6bec2f8bb31addbaf7ecf047d9d8cc 404 PANTHER PTHR13369 105 257 7.9E-84 T 13-09-2016 THL1_RS26850 bc6bec2f8bb31addbaf7ecf047d9d8cc 404 Pfam PF13679 Methyltransferase domain 128 237 6.0E-19 T 13-09-2016 IPR025714 Methyltransferase domain THL1_RS26850 bc6bec2f8bb31addbaf7ecf047d9d8cc 404 Gene3D G3DSA:3.40.50.150 128 235 3.2E-5 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS26850 bc6bec2f8bb31addbaf7ecf047d9d8cc 404 PANTHER PTHR13369:SF1 337 404 7.9E-84 T 13-09-2016 THL1_RS26850 bc6bec2f8bb31addbaf7ecf047d9d8cc 404 SUPERFAMILY SSF53335 128 214 5.17E-8 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS01350 cb8e735dca5336cb0bb477c36827257b 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 112 3.5E-6 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS01350 cb8e735dca5336cb0bb477c36827257b 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 254 268 3.5E-6 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS01350 cb8e735dca5336cb0bb477c36827257b 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 146 159 3.5E-6 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS01350 cb8e735dca5336cb0bb477c36827257b 313 Pfam PF12146 Serine aminopeptidase, S33 68 296 6.6E-24 T 13-09-2016 IPR022742 Serine aminopeptidase, S33 THL1_RS01350 cb8e735dca5336cb0bb477c36827257b 313 Gene3D G3DSA:3.40.50.1820 223 312 4.9E-33 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS01350 cb8e735dca5336cb0bb477c36827257b 313 Gene3D G3DSA:3.40.50.1820 56 182 4.9E-33 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS01350 cb8e735dca5336cb0bb477c36827257b 313 PANTHER PTHR11614 56 305 1.2E-31 T 13-09-2016 THL1_RS01350 cb8e735dca5336cb0bb477c36827257b 313 SUPERFAMILY SSF53474 55 312 4.19E-30 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS09810 8564292512d572e85a2d596d27250f64 316 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 126 2.2E-20 T 13-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 THL1_RS09810 8564292512d572e85a2d596d27250f64 316 Gene3D G3DSA:3.40.50.720 3 199 7.2E-31 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS09810 8564292512d572e85a2d596d27250f64 316 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 153 230 1.0E-11 T 13-09-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 THL1_RS09810 8564292512d572e85a2d596d27250f64 316 PANTHER PTHR22604 3 206 2.2E-23 T 13-09-2016 THL1_RS09810 8564292512d572e85a2d596d27250f64 316 PANTHER PTHR22604:SF123 3 206 2.2E-23 T 13-09-2016 THL1_RS09810 8564292512d572e85a2d596d27250f64 316 SUPERFAMILY SSF51735 3 142 7.32E-23 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 SMART SM00382 227 372 1.2E-6 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 SUPERFAMILY SSF52540 207 450 3.22E-60 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 Pfam PF00989 PAS fold 83 134 3.4E-5 T 13-09-2016 IPR013767 PAS fold GO:0006355 THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 421 430 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 SMART SM00091 82 148 3.4E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 Pfam PF00158 Sigma-54 interaction domain 208 374 1.8E-58 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 SUPERFAMILY SSF55785 84 145 7.99E-9 T 13-09-2016 IPR000014 PAS domain THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 Gene3D G3DSA:3.30.450.20 80 146 1.4E-7 T 13-09-2016 THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 SUPERFAMILY SSF55021 2 72 1.71E-9 T 13-09-2016 THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 231 244 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 Gene3D G3DSA:3.40.50.300 204 380 2.3E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 Pfam PF01842 ACT domain 3 64 3.1E-8 T 13-09-2016 IPR002912 ACT domain GO:0008152|GO:0016597 THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 Gene3D G3DSA:1.10.8.60 386 450 1.0E-18 T 13-09-2016 THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 SUPERFAMILY SSF46689 459 515 2.63E-7 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 PANTHER PTHR32071:SF3 8 519 1.6E-194 T 13-09-2016 THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 Gene3D G3DSA:1.10.10.60 459 516 1.6E-21 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 PANTHER PTHR32071 8 519 1.6E-194 T 13-09-2016 THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 Gene3D G3DSA:3.30.70.260 2 72 1.4E-11 T 13-09-2016 THL1_RS08355 00665ace54e2b0e4e82c77b129c58609 519 TIGRFAM TIGR04381 HTH_TypR: TyrR family helix-turn-helix domain 469 516 4.8E-21 T 13-09-2016 IPR030828 TyrR family, helix-turn-helix domain GO:0003677 THL1_RS27220 45819d204601c1787f136d83bcd44d20 129 SUPERFAMILY SSF51230 3 124 5.1E-42 T 13-09-2016 IPR011053 Single hybrid motif THL1_RS27220 45819d204601c1787f136d83bcd44d20 129 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 13-09-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site THL1_RS27220 45819d204601c1787f136d83bcd44d20 129 Gene3D G3DSA:2.40.50.100 7 124 3.9E-49 T 13-09-2016 THL1_RS27220 45819d204601c1787f136d83bcd44d20 129 PANTHER PTHR11715 1 124 2.9E-66 T 13-09-2016 IPR002930 Glycine cleavage system H-protein THL1_RS27220 45819d204601c1787f136d83bcd44d20 129 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 126 30.925 T 13-09-2016 IPR002930 Glycine cleavage system H-protein THL1_RS27220 45819d204601c1787f136d83bcd44d20 129 PANTHER PTHR11715:SF12 1 124 2.9E-66 T 13-09-2016 THL1_RS27220 45819d204601c1787f136d83bcd44d20 129 Pfam PF01597 Glycine cleavage H-protein 8 124 2.0E-44 T 13-09-2016 IPR002930 Glycine cleavage system H-protein THL1_RS27220 45819d204601c1787f136d83bcd44d20 129 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 127 9.8E-49 T 13-09-2016 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 THL1_RS03580 2d5565f7e366cb9a10b99cea727513b3 104 ProSitePatterns PS01108 Ribosomal protein L24 signature. 7 24 - T 13-09-2016 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03580 2d5565f7e366cb9a10b99cea727513b3 104 Pfam PF00467 KOW motif 7 35 8.9E-6 T 13-09-2016 IPR005824 KOW THL1_RS03580 2d5565f7e366cb9a10b99cea727513b3 104 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 96 21.191 T 13-09-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03580 2d5565f7e366cb9a10b99cea727513b3 104 SMART SM00739 3 30 7.7E-4 T 13-09-2016 IPR005824 KOW THL1_RS03580 2d5565f7e366cb9a10b99cea727513b3 104 SUPERFAMILY SSF50104 3 99 1.76E-33 T 13-09-2016 IPR008991 Translation protein SH3-like domain THL1_RS03580 2d5565f7e366cb9a10b99cea727513b3 104 Gene3D G3DSA:2.30.30.30 3 91 6.2E-22 T 13-09-2016 IPR014722 Ribosomal protein L2 domain 2 THL1_RS03580 2d5565f7e366cb9a10b99cea727513b3 104 PANTHER PTHR12903 3 98 4.9E-45 T 13-09-2016 THL1_RS03580 2d5565f7e366cb9a10b99cea727513b3 104 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 100 1.8E-24 T 13-09-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03580 2d5565f7e366cb9a10b99cea727513b3 104 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 100 4.7E-38 T 13-09-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS09210 0eda76ca867b784313d16287355142f2 361 Gene3D G3DSA:3.40.190.10 134 310 2.6E-69 T 13-09-2016 THL1_RS09210 0eda76ca867b784313d16287355142f2 361 SUPERFAMILY SSF53850 22 360 1.66E-95 T 13-09-2016 THL1_RS09210 0eda76ca867b784313d16287355142f2 361 PIRSF PIRSF019574 3 361 3.3E-131 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09210 0eda76ca867b784313d16287355142f2 361 PANTHER PTHR30222 8 361 5.5E-205 T 13-09-2016 THL1_RS09210 0eda76ca867b784313d16287355142f2 361 Gene3D G3DSA:3.40.190.10 36 133 1.3E-13 T 13-09-2016 THL1_RS09210 0eda76ca867b784313d16287355142f2 361 PANTHER PTHR30222:SF11 8 361 5.5E-205 T 13-09-2016 THL1_RS09210 0eda76ca867b784313d16287355142f2 361 Pfam PF13416 Bacterial extracellular solute-binding protein 38 326 4.3E-32 T 13-09-2016 THL1_RS09210 0eda76ca867b784313d16287355142f2 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 119 135 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09210 0eda76ca867b784313d16287355142f2 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 210 229 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09210 0eda76ca867b784313d16287355142f2 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 27 43 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09210 0eda76ca867b784313d16287355142f2 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 150 164 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09210 0eda76ca867b784313d16287355142f2 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 43 64 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09210 0eda76ca867b784313d16287355142f2 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 86 99 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09210 0eda76ca867b784313d16287355142f2 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 173 192 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09210 0eda76ca867b784313d16287355142f2 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 260 279 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09210 0eda76ca867b784313d16287355142f2 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 70 84 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09210 0eda76ca867b784313d16287355142f2 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 305 331 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS21710 b665748f4e1aa00e6b1a057b3a728bae 372 SUPERFAMILY SSF101790 277 371 2.78E-26 T 13-09-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain THL1_RS21710 b665748f4e1aa00e6b1a057b3a728bae 372 Pfam PF01571 Aminomethyltransferase folate-binding domain 9 256 7.7E-91 T 13-09-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal THL1_RS21710 b665748f4e1aa00e6b1a057b3a728bae 372 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 269 361 1.0E-22 T 13-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS21710 b665748f4e1aa00e6b1a057b3a728bae 372 PIRSF PIRSF006487 1 372 1.6E-83 T 13-09-2016 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS21710 b665748f4e1aa00e6b1a057b3a728bae 372 PANTHER PTHR13847 4 371 2.6E-205 T 13-09-2016 THL1_RS21710 b665748f4e1aa00e6b1a057b3a728bae 372 Gene3D G3DSA:3.30.70.1400 57 140 2.1E-32 T 13-09-2016 THL1_RS21710 b665748f4e1aa00e6b1a057b3a728bae 372 PANTHER PTHR13847:SF209 4 371 2.6E-205 T 13-09-2016 THL1_RS21710 b665748f4e1aa00e6b1a057b3a728bae 372 Gene3D G3DSA:3.30.1360.120 146 233 3.0E-57 T 13-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THL1_RS21710 b665748f4e1aa00e6b1a057b3a728bae 372 Gene3D G3DSA:3.30.1360.120 4 56 3.0E-57 T 13-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THL1_RS21710 b665748f4e1aa00e6b1a057b3a728bae 372 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 5 366 6.4E-108 T 13-09-2016 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS21710 b665748f4e1aa00e6b1a057b3a728bae 372 SUPERFAMILY SSF103025 4 285 2.35E-92 T 13-09-2016 THL1_RS21710 b665748f4e1aa00e6b1a057b3a728bae 372 Gene3D G3DSA:2.40.30.110 284 361 2.0E-26 T 13-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS14055 2d09ef6828a99aa7f07ebbc70a2b6835 578 PANTHER PTHR22642:SF2 18 574 7.7E-110 T 13-09-2016 THL1_RS14055 2d09ef6828a99aa7f07ebbc70a2b6835 578 Gene3D G3DSA:2.30.40.10 501 560 1.6E-12 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS14055 2d09ef6828a99aa7f07ebbc70a2b6835 578 PANTHER PTHR22642 18 574 7.7E-110 T 13-09-2016 THL1_RS14055 2d09ef6828a99aa7f07ebbc70a2b6835 578 Gene3D G3DSA:3.20.20.140 296 500 3.1E-19 T 13-09-2016 THL1_RS14055 2d09ef6828a99aa7f07ebbc70a2b6835 578 SUPERFAMILY SSF51338 514 557 3.6E-23 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS14055 2d09ef6828a99aa7f07ebbc70a2b6835 578 SUPERFAMILY SSF51338 11 78 3.6E-23 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS14055 2d09ef6828a99aa7f07ebbc70a2b6835 578 Gene3D G3DSA:2.30.40.10 16 94 1.3E-15 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS14055 2d09ef6828a99aa7f07ebbc70a2b6835 578 Pfam PF07969 Amidohydrolase family 66 555 7.0E-82 T 13-09-2016 IPR013108 Amidohydrolase 3 THL1_RS14055 2d09ef6828a99aa7f07ebbc70a2b6835 578 SUPERFAMILY SSF51556 218 515 2.62E-21 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS14055 2d09ef6828a99aa7f07ebbc70a2b6835 578 SUPERFAMILY SSF51556 77 141 2.62E-21 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS08840 1f456416e88204b9856ff790af3d98c9 559 SUPERFAMILY SSF52091 437 548 2.16E-16 T 13-09-2016 IPR002645 STAS domain THL1_RS08840 1f456416e88204b9856ff790af3d98c9 559 PANTHER PTHR11814 1 548 1.0E-169 T 13-09-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 THL1_RS08840 1f456416e88204b9856ff790af3d98c9 559 Pfam PF01740 STAS domain 435 545 1.4E-20 T 13-09-2016 IPR002645 STAS domain THL1_RS08840 1f456416e88204b9856ff790af3d98c9 559 Pfam PF00916 Sulfate permease family 17 382 6.9E-85 T 13-09-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 THL1_RS08840 1f456416e88204b9856ff790af3d98c9 559 TIGRFAM TIGR00815 sulP: sulfate permease 2 545 2.1E-120 T 13-09-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 THL1_RS08840 1f456416e88204b9856ff790af3d98c9 559 Gene3D G3DSA:3.30.750.24 437 548 3.9E-18 T 13-09-2016 IPR002645 STAS domain THL1_RS10290 798f985f8736f80b8293a918da4c7936 362 Pfam PF02012 BNR/Asp-box repeat 94 103 0.065 T 13-09-2016 IPR002860 BNR repeat THL1_RS10290 798f985f8736f80b8293a918da4c7936 362 SUPERFAMILY SSF50939 72 348 4.51E-49 T 13-09-2016 IPR011040 Sialidases THL1_RS10290 798f985f8736f80b8293a918da4c7936 362 Pfam PF14870 Photosynthesis system II assembly factor YCF48 149 274 8.8E-16 T 13-09-2016 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain THL1_RS10290 798f985f8736f80b8293a918da4c7936 362 Gene3D G3DSA:2.130.10.140 80 265 6.8E-33 T 13-09-2016 THL1_RS10290 798f985f8736f80b8293a918da4c7936 362 Gene3D G3DSA:2.130.10.140 266 349 1.5E-9 T 13-09-2016 THL1_RS10290 798f985f8736f80b8293a918da4c7936 362 PANTHER PTHR32010 66 269 5.5E-36 T 13-09-2016 THL1_RS25390 4aa7022b5b5bb888a0d1ab47a679cd40 553 PANTHER PTHR10010:SF26 1 459 2.6E-31 T 13-09-2016 THL1_RS25390 4aa7022b5b5bb888a0d1ab47a679cd40 553 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 6 305 5.6E-63 T 13-09-2016 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 THL1_RS25390 4aa7022b5b5bb888a0d1ab47a679cd40 553 SUPERFAMILY SSF109755 329 522 4.29E-21 T 13-09-2016 THL1_RS25390 4aa7022b5b5bb888a0d1ab47a679cd40 553 Pfam PF02690 Na+/Pi-cotransporter 16 150 9.1E-34 T 13-09-2016 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: REACT_15518 THL1_RS25390 4aa7022b5b5bb888a0d1ab47a679cd40 553 Pfam PF02690 Na+/Pi-cotransporter 142 249 2.9E-12 T 13-09-2016 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: REACT_15518 THL1_RS25390 4aa7022b5b5bb888a0d1ab47a679cd40 553 PANTHER PTHR10010 1 459 2.6E-31 T 13-09-2016 THL1_RS25390 4aa7022b5b5bb888a0d1ab47a679cd40 553 Pfam PF01895 PhoU domain 339 419 6.5E-6 T 13-09-2016 IPR026022 PhoU domain THL1_RS25390 4aa7022b5b5bb888a0d1ab47a679cd40 553 Gene3D G3DSA:1.20.58.220 444 521 2.6E-4 T 13-09-2016 THL1_RS25390 4aa7022b5b5bb888a0d1ab47a679cd40 553 Gene3D G3DSA:1.20.58.220 330 419 1.7E-6 T 13-09-2016 THL1_RS00885 82745b6aceb0275181c420078c1fe573 277 PANTHER PTHR30468 1 277 8.3E-97 T 13-09-2016 THL1_RS00885 82745b6aceb0275181c420078c1fe573 277 Gene3D G3DSA:3.60.130.10 2 277 9.9E-97 T 13-09-2016 THL1_RS00885 82745b6aceb0275181c420078c1fe573 277 SUPERFAMILY SSF51197 3 277 9.62E-97 T 13-09-2016 THL1_RS00885 82745b6aceb0275181c420078c1fe573 277 PANTHER PTHR30468:SF2 1 277 8.3E-97 T 13-09-2016 THL1_RS00885 82745b6aceb0275181c420078c1fe573 277 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 6 270 3.2E-70 T 13-09-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: REACT_13 THL1_RS00970 4855c5facf53ead552c4d546feaea666 452 Pfam PF00120 Glutamine synthetase, catalytic domain 115 446 5.6E-106 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS00970 4855c5facf53ead552c4d546feaea666 452 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 250 265 - T 13-09-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS00970 4855c5facf53ead552c4d546feaea666 452 Gene3D G3DSA:3.10.20.70 6 117 9.0E-15 T 13-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS00970 4855c5facf53ead552c4d546feaea666 452 PANTHER PTHR20852:SF63 1 452 0.0 T 13-09-2016 THL1_RS00970 4855c5facf53ead552c4d546feaea666 452 PANTHER PTHR20852 1 452 0.0 T 13-09-2016 THL1_RS00970 4855c5facf53ead552c4d546feaea666 452 SMART SM01230 114 370 2.3E-108 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS00970 4855c5facf53ead552c4d546feaea666 452 Gene3D G3DSA:3.30.590.10 118 438 1.2E-91 T 13-09-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 THL1_RS00970 4855c5facf53ead552c4d546feaea666 452 SUPERFAMILY SSF54368 6 113 1.44E-17 T 13-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS00970 4855c5facf53ead552c4d546feaea666 452 SUPERFAMILY SSF55931 114 449 6.08E-105 T 13-09-2016 THL1_RS18785 f3ef0e094f2463de136bcc4f2cd6fdbb 392 Gene3D G3DSA:2.40.10.220 21 119 3.2E-7 T 13-09-2016 THL1_RS18785 f3ef0e094f2463de136bcc4f2cd6fdbb 392 Gene3D G3DSA:2.40.50.100 203 296 5.8E-8 T 13-09-2016 THL1_RS18785 f3ef0e094f2463de136bcc4f2cd6fdbb 392 Pfam PF07238 PilZ domain 20 119 5.3E-9 T 13-09-2016 IPR009875 PilZ domain GO:0035438 THL1_RS18785 f3ef0e094f2463de136bcc4f2cd6fdbb 392 SUPERFAMILY SSF141371 14 135 1.47E-13 T 13-09-2016 THL1_RS18785 f3ef0e094f2463de136bcc4f2cd6fdbb 392 Pfam PF13437 HlyD family secretion protein 267 342 2.6E-7 T 13-09-2016 THL1_RS09710 09ce209f39beca9f3ed6b6468a192e46 474 SUPERFAMILY SSF53720 2 472 3.8E-157 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS09710 09ce209f39beca9f3ed6b6468a192e46 474 Gene3D G3DSA:3.40.605.10 2 259 1.3E-95 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS09710 09ce209f39beca9f3ed6b6468a192e46 474 PANTHER PTHR11699 1 474 1.9E-288 T 13-09-2016 THL1_RS09710 09ce209f39beca9f3ed6b6468a192e46 474 Pfam PF00171 Aldehyde dehydrogenase family 19 470 4.4E-164 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS09710 09ce209f39beca9f3ed6b6468a192e46 474 Gene3D G3DSA:3.40.309.10 260 450 4.0E-61 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS09710 09ce209f39beca9f3ed6b6468a192e46 474 PANTHER PTHR11699:SF109 1 474 1.9E-288 T 13-09-2016 IPR015657 Aminobutyraldehyde dehydrogenase KEGG: 00330+1.2.1.19|KEGG: 00410+1.2.1.19|MetaCyc: PWY-2|MetaCyc: PWY-3|UniPathway: UPA00188 THL1_RS09710 09ce209f39beca9f3ed6b6468a192e46 474 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 245 252 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS10535 51bf7e6f85be08f7a77eba6f0ba108ad 340 SUPERFAMILY SSF46689 287 336 4.48E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS10535 51bf7e6f85be08f7a77eba6f0ba108ad 340 Gene3D G3DSA:1.10.10.60 287 337 2.0E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS10535 51bf7e6f85be08f7a77eba6f0ba108ad 340 PANTHER PTHR11019 123 339 3.0E-67 T 13-09-2016 THL1_RS10535 51bf7e6f85be08f7a77eba6f0ba108ad 340 SMART SM00342 252 334 2.5E-22 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS10535 51bf7e6f85be08f7a77eba6f0ba108ad 340 Pfam PF12833 Helix-turn-helix domain 258 335 3.2E-20 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS10535 51bf7e6f85be08f7a77eba6f0ba108ad 340 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 23 208 4.4E-52 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS10535 51bf7e6f85be08f7a77eba6f0ba108ad 340 PANTHER PTHR11019:SF52 123 339 3.0E-67 T 13-09-2016 THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 601 618 - T 13-09-2016 IPR001882 Biotin-binding site THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 Pfam PF00364 Biotin-requiring enzyme 579 644 6.3E-17 T 13-09-2016 IPR000089 Biotin/lipoyl attachment THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 Gene3D G3DSA:2.40.50.100 577 645 1.7E-24 T 13-09-2016 THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 SUPERFAMILY SSF51230 570 645 9.68E-21 T 13-09-2016 IPR011053 Single hybrid motif THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 Gene3D G3DSA:3.30.1490.20 129 202 6.2E-31 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 Gene3D G3DSA:3.40.50.20 1 128 1.0E-48 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 SUPERFAMILY SSF56059 83 348 1.66E-69 T 13-09-2016 THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 2.3E-80 T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 SMART SM00878 336 443 4.4E-57 T 13-09-2016 IPR005482 Biotin carboxylase, C-terminal THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 Pfam PF02785 Biotin carboxylase C-terminal domain 336 443 8.0E-38 T 13-09-2016 IPR005482 Biotin carboxylase, C-terminal THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 SUPERFAMILY SSF52440 1 113 5.61E-45 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.1E-42 T 13-09-2016 IPR005481 Biotin carboxylase-like, N-terminal domain THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 PANTHER PTHR18866:SF102 1 646 0.0 T 13-09-2016 THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 Gene3D G3DSA:3.30.470.20 205 448 3.0E-104 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 PANTHER PTHR18866 1 646 0.0 T 13-09-2016 THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 SUPERFAMILY SSF51246 332 449 4.13E-40 T 13-09-2016 IPR011054 Rudiment single hybrid motif THL1_RS15895 1fab3eaa326d9fd878e396f4c30f80d0 647 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS14015 cb69e49ee55854f8c980cd48b8720603 294 PANTHER PTHR30537 1 292 2.1E-75 T 13-09-2016 THL1_RS14015 cb69e49ee55854f8c980cd48b8720603 294 Gene3D G3DSA:1.10.10.10 2 87 4.0E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14015 cb69e49ee55854f8c980cd48b8720603 294 PANTHER PTHR30537:SF15 1 292 2.1E-75 T 13-09-2016 THL1_RS14015 cb69e49ee55854f8c980cd48b8720603 294 Gene3D G3DSA:3.40.190.10 93 186 5.3E-27 T 13-09-2016 THL1_RS14015 cb69e49ee55854f8c980cd48b8720603 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 5.1E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14015 cb69e49ee55854f8c980cd48b8720603 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 5.1E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14015 cb69e49ee55854f8c980cd48b8720603 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 5.1E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14015 cb69e49ee55854f8c980cd48b8720603 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 67 5.3E-18 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14015 cb69e49ee55854f8c980cd48b8720603 294 Pfam PF03466 LysR substrate binding domain 89 293 5.3E-40 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS14015 cb69e49ee55854f8c980cd48b8720603 294 SUPERFAMILY SSF46785 11 112 3.9E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14015 cb69e49ee55854f8c980cd48b8720603 294 SUPERFAMILY SSF53850 91 293 6.21E-39 T 13-09-2016 THL1_RS14015 cb69e49ee55854f8c980cd48b8720603 294 Gene3D G3DSA:3.40.190.10 187 263 6.6E-4 T 13-09-2016 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 Gene3D G3DSA:1.10.730.10 457 579 3.4E-34 T 13-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 127 138 - T 13-09-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 SMART SM00836 463 579 1.4E-36 T 13-09-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 SUPERFAMILY SSF55190 1 104 3.14E-24 T 13-09-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 Pfam PF00750 tRNA synthetases class I (R) 100 449 6.2E-128 T 13-09-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 PANTHER PTHR11956 1 579 1.2E-253 T 13-09-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 Gene3D G3DSA:3.40.50.620 115 456 1.5E-111 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 SUPERFAMILY SSF47323 457 579 1.7E-34 T 13-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 PRINTS PR01038 Arginyl-tRNA synthetase signature 158 171 8.1E-25 T 13-09-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 PRINTS PR01038 Arginyl-tRNA synthetase signature 134 150 8.1E-25 T 13-09-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 PRINTS PR01038 Arginyl-tRNA synthetase signature 119 134 8.1E-25 T 13-09-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 PRINTS PR01038 Arginyl-tRNA synthetase signature 306 327 8.1E-25 T 13-09-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 4 90 6.1E-25 T 13-09-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 SUPERFAMILY SSF52374 114 456 1.95E-89 T 13-09-2016 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 Hamap MF_00123 Arginine--tRNA ligase [argS]. 3 579 27.069 T 13-09-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 SMART SM01016 3 91 7.1E-37 T 13-09-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 Pfam PF05746 DALR anticodon binding domain 463 579 1.3E-32 T 13-09-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 Gene3D G3DSA:3.30.1360.70 2 109 4.6E-32 T 13-09-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 PANTHER PTHR11956:SF1 1 579 1.2E-253 T 13-09-2016 THL1_RS26360 efc0b7fa5332da1624a73319f54501b0 579 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 2 579 1.1E-169 T 13-09-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 THL1_RS15500 e2cbc9a922d3dda20a6dc6d0e8d9b8c9 209 SUPERFAMILY SSF52833 49 181 1.1E-22 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS15500 e2cbc9a922d3dda20a6dc6d0e8d9b8c9 209 Pfam PF00578 AhpC/TSA family 52 165 7.8E-11 T 13-09-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS15500 e2cbc9a922d3dda20a6dc6d0e8d9b8c9 209 Gene3D G3DSA:3.40.30.10 52 179 5.5E-18 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS15770 c17cad5d97340436aa0ab389d5149cac 548 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 176 201 - T 13-09-2016 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 THL1_RS15770 c17cad5d97340436aa0ab389d5149cac 548 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 61 467 1.5E-57 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS15770 c17cad5d97340436aa0ab389d5149cac 548 PANTHER PTHR11819 30 537 4.5E-255 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS15770 c17cad5d97340436aa0ab389d5149cac 548 Pfam PF00474 Sodium:solute symporter family 61 467 8.2E-113 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS15770 c17cad5d97340436aa0ab389d5149cac 548 PANTHER PTHR11819:SF13 30 537 4.5E-255 T 13-09-2016 THL1_RS07235 3552e7bed81ee565bc22c9fb6500ad1c 288 PIRSF PIRSF006232 1 288 9.7E-87 T 13-09-2016 IPR012093 Pirin THL1_RS07235 3552e7bed81ee565bc22c9fb6500ad1c 288 PANTHER PTHR13903:SF12 1 288 7.4E-161 T 13-09-2016 THL1_RS07235 3552e7bed81ee565bc22c9fb6500ad1c 288 SUPERFAMILY SSF51182 1 287 8.34E-86 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS07235 3552e7bed81ee565bc22c9fb6500ad1c 288 Pfam PF02678 Pirin 22 127 2.5E-33 T 13-09-2016 IPR003829 Pirin, N-terminal domain THL1_RS07235 3552e7bed81ee565bc22c9fb6500ad1c 288 Pfam PF05726 Pirin C-terminal cupin domain 182 284 4.6E-29 T 13-09-2016 IPR008778 Pirin, C-terminal domain THL1_RS07235 3552e7bed81ee565bc22c9fb6500ad1c 288 PANTHER PTHR13903 1 288 7.4E-161 T 13-09-2016 IPR012093 Pirin THL1_RS07235 3552e7bed81ee565bc22c9fb6500ad1c 288 Gene3D G3DSA:2.60.120.10 2 257 3.3E-77 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS12035 2f15d9329b12cd2d60c6c83392f0ab93 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 68 2.5E-16 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS12035 2f15d9329b12cd2d60c6c83392f0ab93 305 SUPERFAMILY SSF46785 7 89 2.58E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12035 2f15d9329b12cd2d60c6c83392f0ab93 305 SUPERFAMILY SSF53850 93 295 8.32E-37 T 13-09-2016 THL1_RS12035 2f15d9329b12cd2d60c6c83392f0ab93 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 9.8E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS12035 2f15d9329b12cd2d60c6c83392f0ab93 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 9.8E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS12035 2f15d9329b12cd2d60c6c83392f0ab93 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 9.8E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS12035 2f15d9329b12cd2d60c6c83392f0ab93 305 Gene3D G3DSA:3.40.190.10 93 176 9.2E-24 T 13-09-2016 THL1_RS12035 2f15d9329b12cd2d60c6c83392f0ab93 305 Gene3D G3DSA:3.40.190.10 273 300 9.2E-24 T 13-09-2016 THL1_RS12035 2f15d9329b12cd2d60c6c83392f0ab93 305 PANTHER PTHR30118:SF8 1 295 5.1E-112 T 13-09-2016 THL1_RS12035 2f15d9329b12cd2d60c6c83392f0ab93 305 Pfam PF03466 LysR substrate binding domain 101 295 6.1E-20 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS12035 2f15d9329b12cd2d60c6c83392f0ab93 305 Gene3D G3DSA:1.10.10.10 2 89 1.5E-29 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12035 2f15d9329b12cd2d60c6c83392f0ab93 305 Gene3D G3DSA:3.40.190.10 183 267 2.2E-23 T 13-09-2016 THL1_RS12035 2f15d9329b12cd2d60c6c83392f0ab93 305 PANTHER PTHR30118 1 295 5.1E-112 T 13-09-2016 THL1_RS25370 192ac20785396101c0673e3bc75635a8 643 SMART SM00304 312 366 3.2E-12 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS25370 192ac20785396101c0673e3bc75635a8 643 Gene3D G3DSA:3.30.450.20 167 291 2.2E-22 T 13-09-2016 THL1_RS25370 192ac20785396101c0673e3bc75635a8 643 SMART SM00283 381 642 4.9E-79 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS25370 192ac20785396101c0673e3bc75635a8 643 Pfam PF00672 HAMP domain 294 360 2.4E-14 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS25370 192ac20785396101c0673e3bc75635a8 643 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 439 641 1.7E-48 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS25370 192ac20785396101c0673e3bc75635a8 643 SUPERFAMILY SSF58104 334 643 3.01E-77 T 13-09-2016 THL1_RS25370 192ac20785396101c0673e3bc75635a8 643 Pfam PF02743 Cache domain 51 274 1.2E-19 T 13-09-2016 IPR033479 Double Cache domain 1 THL1_RS25370 192ac20785396101c0673e3bc75635a8 643 PANTHER PTHR32089:SF39 140 643 1.7E-147 T 13-09-2016 THL1_RS25370 192ac20785396101c0673e3bc75635a8 643 Gene3D G3DSA:1.10.287.950 395 612 4.2E-58 T 13-09-2016 THL1_RS25370 192ac20785396101c0673e3bc75635a8 643 PANTHER PTHR32089 140 643 1.7E-147 T 13-09-2016 THL1_RS21885 315a290ec603e00ce3fbb0a610605c08 379 PANTHER PTHR24559 138 323 4.4E-21 T 13-09-2016 THL1_RS21885 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF46689 8 116 1.74E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21885 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF13565 Homeodomain-like domain 39 112 1.0E-11 T 13-09-2016 THL1_RS21885 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:1.10.10.60 11 57 2.5E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21885 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF53098 138 302 2.28E-35 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS21885 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF00665 Integrase core domain 138 259 1.7E-24 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS21885 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:3.30.420.10 132 296 5.9E-38 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS03945 315a290ec603e00ce3fbb0a610605c08 379 PANTHER PTHR24559 138 323 4.4E-21 T 13-09-2016 THL1_RS03945 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF46689 8 116 1.74E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS03945 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF13565 Homeodomain-like domain 39 112 1.0E-11 T 13-09-2016 THL1_RS03945 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:1.10.10.60 11 57 2.5E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS03945 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF53098 138 302 2.28E-35 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS03945 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF00665 Integrase core domain 138 259 1.7E-24 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS03945 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:3.30.420.10 132 296 5.9E-38 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS18725 315a290ec603e00ce3fbb0a610605c08 379 PANTHER PTHR24559 138 323 4.4E-21 T 13-09-2016 THL1_RS18725 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF46689 8 116 1.74E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS18725 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF13565 Homeodomain-like domain 39 112 1.0E-11 T 13-09-2016 THL1_RS18725 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:1.10.10.60 11 57 2.5E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS18725 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF53098 138 302 2.28E-35 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS18725 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF00665 Integrase core domain 138 259 1.7E-24 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS18725 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:3.30.420.10 132 296 5.9E-38 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS06320 315a290ec603e00ce3fbb0a610605c08 379 PANTHER PTHR24559 138 323 4.4E-21 T 13-09-2016 THL1_RS06320 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF46689 8 116 1.74E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS06320 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF13565 Homeodomain-like domain 39 112 1.0E-11 T 13-09-2016 THL1_RS06320 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:1.10.10.60 11 57 2.5E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS06320 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF53098 138 302 2.28E-35 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS06320 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF00665 Integrase core domain 138 259 1.7E-24 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS06320 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:3.30.420.10 132 296 5.9E-38 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS00525 315a290ec603e00ce3fbb0a610605c08 379 PANTHER PTHR24559 138 323 4.4E-21 T 13-09-2016 THL1_RS00525 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF46689 8 116 1.74E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS00525 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF13565 Homeodomain-like domain 39 112 1.0E-11 T 13-09-2016 THL1_RS00525 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:1.10.10.60 11 57 2.5E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS00525 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF53098 138 302 2.28E-35 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS00525 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF00665 Integrase core domain 138 259 1.7E-24 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS00525 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:3.30.420.10 132 296 5.9E-38 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS28245 315a290ec603e00ce3fbb0a610605c08 379 PANTHER PTHR24559 138 323 4.4E-21 T 13-09-2016 THL1_RS28245 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF46689 8 116 1.74E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS28245 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF13565 Homeodomain-like domain 39 112 1.0E-11 T 13-09-2016 THL1_RS28245 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:1.10.10.60 11 57 2.5E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS28245 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF53098 138 302 2.28E-35 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS28245 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF00665 Integrase core domain 138 259 1.7E-24 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS28245 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:3.30.420.10 132 296 5.9E-38 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS13415 315a290ec603e00ce3fbb0a610605c08 379 PANTHER PTHR24559 138 323 4.4E-21 T 13-09-2016 THL1_RS13415 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF46689 8 116 1.74E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13415 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF13565 Homeodomain-like domain 39 112 1.0E-11 T 13-09-2016 THL1_RS13415 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:1.10.10.60 11 57 2.5E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13415 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF53098 138 302 2.28E-35 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS13415 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF00665 Integrase core domain 138 259 1.7E-24 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS13415 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:3.30.420.10 132 296 5.9E-38 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS19700 315a290ec603e00ce3fbb0a610605c08 379 PANTHER PTHR24559 138 323 4.4E-21 T 13-09-2016 THL1_RS19700 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF46689 8 116 1.74E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19700 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF13565 Homeodomain-like domain 39 112 1.0E-11 T 13-09-2016 THL1_RS19700 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:1.10.10.60 11 57 2.5E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19700 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF53098 138 302 2.28E-35 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS19700 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF00665 Integrase core domain 138 259 1.7E-24 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS19700 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:3.30.420.10 132 296 5.9E-38 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS15295 315a290ec603e00ce3fbb0a610605c08 379 PANTHER PTHR24559 138 323 4.4E-21 T 13-09-2016 THL1_RS15295 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF46689 8 116 1.74E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15295 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF13565 Homeodomain-like domain 39 112 1.0E-11 T 13-09-2016 THL1_RS15295 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:1.10.10.60 11 57 2.5E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15295 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF53098 138 302 2.28E-35 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS15295 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF00665 Integrase core domain 138 259 1.7E-24 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS15295 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:3.30.420.10 132 296 5.9E-38 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS16030 315a290ec603e00ce3fbb0a610605c08 379 PANTHER PTHR24559 138 323 4.4E-21 T 13-09-2016 THL1_RS16030 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF46689 8 116 1.74E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS16030 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF13565 Homeodomain-like domain 39 112 1.0E-11 T 13-09-2016 THL1_RS16030 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:1.10.10.60 11 57 2.5E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS16030 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF53098 138 302 2.28E-35 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS16030 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF00665 Integrase core domain 138 259 1.7E-24 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS16030 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:3.30.420.10 132 296 5.9E-38 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS28280 315a290ec603e00ce3fbb0a610605c08 379 PANTHER PTHR24559 138 323 4.4E-21 T 13-09-2016 THL1_RS28280 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF46689 8 116 1.74E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS28280 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF13565 Homeodomain-like domain 39 112 1.0E-11 T 13-09-2016 THL1_RS28280 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:1.10.10.60 11 57 2.5E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS28280 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF53098 138 302 2.28E-35 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS28280 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF00665 Integrase core domain 138 259 1.7E-24 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS28280 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:3.30.420.10 132 296 5.9E-38 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS14440 315a290ec603e00ce3fbb0a610605c08 379 PANTHER PTHR24559 138 323 4.4E-21 T 13-09-2016 THL1_RS14440 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF46689 8 116 1.74E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS14440 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF13565 Homeodomain-like domain 39 112 1.0E-11 T 13-09-2016 THL1_RS14440 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:1.10.10.60 11 57 2.5E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS14440 315a290ec603e00ce3fbb0a610605c08 379 SUPERFAMILY SSF53098 138 302 2.28E-35 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS14440 315a290ec603e00ce3fbb0a610605c08 379 Pfam PF00665 Integrase core domain 138 259 1.7E-24 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS14440 315a290ec603e00ce3fbb0a610605c08 379 Gene3D G3DSA:3.30.420.10 132 296 5.9E-38 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS27245 9f6eac5777ddf937fe1c31bfd4267ff1 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 5.1E-13 T 13-09-2016 THL1_RS27245 9f6eac5777ddf937fe1c31bfd4267ff1 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 5.1E-13 T 13-09-2016 THL1_RS27245 9f6eac5777ddf937fe1c31bfd4267ff1 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 5.1E-13 T 13-09-2016 THL1_RS27245 9f6eac5777ddf937fe1c31bfd4267ff1 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 5.1E-13 T 13-09-2016 THL1_RS27245 9f6eac5777ddf937fe1c31bfd4267ff1 395 SUPERFAMILY SSF51905 277 393 5.18E-51 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27245 9f6eac5777ddf937fe1c31bfd4267ff1 395 SUPERFAMILY SSF51905 4 178 5.18E-51 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27245 9f6eac5777ddf937fe1c31bfd4267ff1 395 PANTHER PTHR13789 1 395 1.3E-168 T 13-09-2016 THL1_RS27245 9f6eac5777ddf937fe1c31bfd4267ff1 395 TIGRFAM TIGR01984 UbiH: 2-polyprenyl-6-methoxyphenol 4-hydroxylase 6 389 2.2E-136 T 13-09-2016 IPR011295 2-polyprenyl-6-methoxyphenol 4-hydroxylase GO:0006744|GO:0008681 KEGG: 00130+1.14.13.-|KEGG: 00140+1.14.13.-|KEGG: 00232+1.14.13.-|KEGG: 00261+1.14.13.-|KEGG: 00340+1.14.13.-|KEGG: 00360+1.14.13.-|KEGG: 00361+1.14.13.-|KEGG: 00362+1.14.13.-|KEGG: 00363+1.14.13.-|KEGG: 00380+1.14.13.-|KEGG: 00403+1.14.13.-|KEGG: 00590+1.14.13.-|KEGG: 00591+1.14.13.-|KEGG: 00622+1.14.13.-|KEGG: 00623+1.14.13.-|KEGG: 00624+1.14.13.-|KEGG: 00625+1.14.13.-|KEGG: 00626+1.14.13.-|KEGG: 00627+1.14.13.-|KEGG: 00640+1.14.13.-|KEGG: 00643+1.14.13.-|KEGG: 00830+1.14.13.-|KEGG: 00903+1.14.13.-|KEGG: 00904+1.14.13.-|KEGG: 00905+1.14.13.-|KEGG: 00906+1.14.13.-|KEGG: 00930+1.14.13.-|KEGG: 00940+1.14.13.-|KEGG: 00941+1.14.13.-|KEGG: 00943+1.14.13.-|KEGG: 00945+1.14.13.-|KEGG: 00950+1.14.13.-|KEGG: 00966+1.14.13.-|KEGG: 00980+1.14.13.-|KEGG: 00982+1.14.13.-|KEGG: 00983+1.14.13.-|UniPathway: UPA00232 THL1_RS27245 9f6eac5777ddf937fe1c31bfd4267ff1 395 Gene3D G3DSA:3.50.50.60 5 183 1.8E-34 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27245 9f6eac5777ddf937fe1c31bfd4267ff1 395 Gene3D G3DSA:3.50.50.60 269 355 1.8E-34 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27245 9f6eac5777ddf937fe1c31bfd4267ff1 395 PANTHER PTHR13789:SF214 1 395 1.3E-168 T 13-09-2016 THL1_RS27245 9f6eac5777ddf937fe1c31bfd4267ff1 395 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 6 389 4.8E-123 T 13-09-2016 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 UniPathway: UPA00232 THL1_RS27245 9f6eac5777ddf937fe1c31bfd4267ff1 395 Pfam PF01494 FAD binding domain 4 318 7.9E-19 T 13-09-2016 IPR002938 FAD-binding domain GO:0071949 THL1_RS06895 ba50a4180aba7b84350d4f6ce58fe70b 154 PANTHER PTHR32481 17 118 2.0E-47 T 13-09-2016 THL1_RS06895 ba50a4180aba7b84350d4f6ce58fe70b 154 Pfam PF05343 M42 glutamyl aminopeptidase 14 99 2.0E-15 T 13-09-2016 IPR008007 Peptidase M42 THL1_RS06895 ba50a4180aba7b84350d4f6ce58fe70b 154 SUPERFAMILY SSF53187 11 106 2.25E-13 T 13-09-2016 THL1_RS06895 ba50a4180aba7b84350d4f6ce58fe70b 154 Gene3D G3DSA:3.40.630.10 15 106 1.6E-9 T 13-09-2016 THL1_RS06895 ba50a4180aba7b84350d4f6ce58fe70b 154 PANTHER PTHR32481:SF7 17 118 2.0E-47 T 13-09-2016 THL1_RS07460 3c7767a7a3178aa642df01dfe4c3bd62 439 Pfam PF00909 Ammonium Transporter Family 38 435 2.9E-108 T 13-09-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 THL1_RS07460 3c7767a7a3178aa642df01dfe4c3bd62 439 PANTHER PTHR11730 26 438 8.9E-150 T 13-09-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 THL1_RS07460 3c7767a7a3178aa642df01dfe4c3bd62 439 Gene3D G3DSA:1.10.3430.10 30 415 7.1E-130 T 13-09-2016 IPR029020 Ammonium/urea transporter THL1_RS07460 3c7767a7a3178aa642df01dfe4c3bd62 439 TIGRFAM TIGR00836 amt: ammonium transporter 36 435 3.4E-120 T 13-09-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 THL1_RS07460 3c7767a7a3178aa642df01dfe4c3bd62 439 SUPERFAMILY SSF111352 32 411 3.66E-119 T 13-09-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 THL1_RS07460 3c7767a7a3178aa642df01dfe4c3bd62 439 PANTHER PTHR11730:SF17 26 438 8.9E-150 T 13-09-2016 THL1_RS09510 cf98488bed3f081d132cb43c395af2ac 435 TIGRFAM TIGR02967 guan_deamin: guanine deaminase 28 428 6.9E-195 T 13-09-2016 IPR014311 Guanine deaminase GO:0006147|GO:0008270|GO:0008892 KEGG: 00230+3.5.4.3|MetaCyc: PWY-5497|MetaCyc: PWY-6606|MetaCyc: PWY-6608|MetaCyc: PWY-7442|UniPathway: UPA00603 THL1_RS09510 cf98488bed3f081d132cb43c395af2ac 435 PANTHER PTHR11271 29 434 1.2E-168 T 13-09-2016 THL1_RS09510 cf98488bed3f081d132cb43c395af2ac 435 Pfam PF01979 Amidohydrolase family 70 430 1.0E-71 T 13-09-2016 IPR006680 Amidohydrolase-related GO:0016787 THL1_RS09510 cf98488bed3f081d132cb43c395af2ac 435 Gene3D G3DSA:3.20.20.140 79 374 4.4E-120 T 13-09-2016 THL1_RS09510 cf98488bed3f081d132cb43c395af2ac 435 Gene3D G3DSA:2.30.40.10 29 78 7.8E-10 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS09510 cf98488bed3f081d132cb43c395af2ac 435 SUPERFAMILY SSF51338 22 90 1.3E-10 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS09510 cf98488bed3f081d132cb43c395af2ac 435 PANTHER PTHR11271:SF6 29 434 1.2E-168 T 13-09-2016 IPR014311 Guanine deaminase GO:0006147|GO:0008270|GO:0008892 KEGG: 00230+3.5.4.3|MetaCyc: PWY-5497|MetaCyc: PWY-6606|MetaCyc: PWY-6608|MetaCyc: PWY-7442|UniPathway: UPA00603 THL1_RS09510 cf98488bed3f081d132cb43c395af2ac 435 SUPERFAMILY SSF51556 72 375 1.6E-105 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS15340 6de891bf1ee0b10ad2dc20c74ce2d24d 287 Pfam PF00753 Metallo-beta-lactamase superfamily 16 204 2.5E-21 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS15340 6de891bf1ee0b10ad2dc20c74ce2d24d 287 SUPERFAMILY SSF56281 8 286 1.27E-49 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS15340 6de891bf1ee0b10ad2dc20c74ce2d24d 287 PANTHER PTHR11935:SF110 5 282 7.4E-135 T 13-09-2016 THL1_RS15340 6de891bf1ee0b10ad2dc20c74ce2d24d 287 Gene3D G3DSA:3.60.15.10 7 252 2.1E-50 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS15340 6de891bf1ee0b10ad2dc20c74ce2d24d 287 SMART SM00849 14 204 6.9E-23 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS15340 6de891bf1ee0b10ad2dc20c74ce2d24d 287 PANTHER PTHR11935 5 282 7.4E-135 T 13-09-2016 THL1_RS18810 94c7cd994c201898642ca62dd42fca35 478 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 12 443 7.5E-116 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS18810 94c7cd994c201898642ca62dd42fca35 478 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 8 469 1.7E-235 T 13-09-2016 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS18810 94c7cd994c201898642ca62dd42fca35 478 Gene3D G3DSA:1.20.210.10 8 467 1.2E-73 T 13-09-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS18810 94c7cd994c201898642ca62dd42fca35 478 PANTHER PTHR10422:SF21 7 467 0.0 T 13-09-2016 THL1_RS18810 94c7cd994c201898642ca62dd42fca35 478 PANTHER PTHR10422 7 467 0.0 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS18810 94c7cd994c201898642ca62dd42fca35 478 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 203 258 - T 13-09-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS18810 94c7cd994c201898642ca62dd42fca35 478 SUPERFAMILY SSF81442 8 467 2.09E-127 T 13-09-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS26060 2ab6bab9e1518258f9f00113b3350389 401 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 393 3.9E-39 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS26060 2ab6bab9e1518258f9f00113b3350389 401 SUPERFAMILY SSF56645 69 253 3.27E-46 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS26060 2ab6bab9e1518258f9f00113b3350389 401 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 225 7.7E-23 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS26060 2ab6bab9e1518258f9f00113b3350389 401 Gene3D G3DSA:2.40.110.10 129 234 8.2E-38 T 13-09-2016 THL1_RS26060 2ab6bab9e1518258f9f00113b3350389 401 SUPERFAMILY SSF47203 240 396 2.09E-35 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS26060 2ab6bab9e1518258f9f00113b3350389 401 Gene3D G3DSA:1.20.140.10 242 395 4.7E-48 T 13-09-2016 THL1_RS26060 2ab6bab9e1518258f9f00113b3350389 401 PANTHER PTHR10909 77 401 1.7E-85 T 13-09-2016 THL1_RS26060 2ab6bab9e1518258f9f00113b3350389 401 Gene3D G3DSA:1.10.540.10 1 124 3.6E-8 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS02830 bfd65c6455772460489cfdd70410a620 466 TIGRFAM TIGR01773 GABAperm: GABA permease 2 450 2.0E-222 T 13-09-2016 IPR011265 GABA permease GO:0015185|GO:0015812|GO:0016021 THL1_RS02830 bfd65c6455772460489cfdd70410a620 466 PIRSF PIRSF006060 1 463 2.8E-72 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS02830 bfd65c6455772460489cfdd70410a620 466 PANTHER PTHR11785 2 457 4.0E-244 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS02830 bfd65c6455772460489cfdd70410a620 466 Pfam PF00324 Amino acid permease 17 453 1.1E-117 T 13-09-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 THL1_RS02830 bfd65c6455772460489cfdd70410a620 466 PANTHER PTHR11785:SF24 2 457 4.0E-244 T 13-09-2016 THL1_RS02830 bfd65c6455772460489cfdd70410a620 466 ProSitePatterns PS00218 Amino acid permeases signature. 42 72 - T 13-09-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 THL1_RS10330 fd9a91dcff9afde35d115c2aa47fd5c8 1620 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 77 1607 0.0 T 13-09-2016 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 THL1_RS10330 fd9a91dcff9afde35d115c2aa47fd5c8 1620 PANTHER PTHR11606 675 1103 0.0 T 13-09-2016 THL1_RS10330 fd9a91dcff9afde35d115c2aa47fd5c8 1620 PANTHER PTHR11606 50 151 0.0 T 13-09-2016 THL1_RS10330 fd9a91dcff9afde35d115c2aa47fd5c8 1620 PANTHER PTHR11606 219 566 0.0 T 13-09-2016 THL1_RS10330 fd9a91dcff9afde35d115c2aa47fd5c8 1620 PANTHER PTHR11606 1128 1373 0.0 T 13-09-2016 THL1_RS10330 fd9a91dcff9afde35d115c2aa47fd5c8 1620 SUPERFAMILY SSF51735 951 1053 2.69E-27 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10330 fd9a91dcff9afde35d115c2aa47fd5c8 1620 SUPERFAMILY SSF51735 1089 1219 2.69E-27 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10330 fd9a91dcff9afde35d115c2aa47fd5c8 1620 Gene3D G3DSA:3.40.50.720 1114 1186 8.7E-33 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10330 fd9a91dcff9afde35d115c2aa47fd5c8 1620 Gene3D G3DSA:3.40.50.720 948 1059 8.7E-33 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10330 fd9a91dcff9afde35d115c2aa47fd5c8 1620 PIRSF PIRSF036761 2 1614 0.0 T 13-09-2016 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 THL1_RS10330 fd9a91dcff9afde35d115c2aa47fd5c8 1620 PANTHER PTHR11606:SF1 50 151 0.0 T 13-09-2016 THL1_RS10330 fd9a91dcff9afde35d115c2aa47fd5c8 1620 PANTHER PTHR11606:SF1 219 566 0.0 T 13-09-2016 THL1_RS10330 fd9a91dcff9afde35d115c2aa47fd5c8 1620 PANTHER PTHR11606:SF1 1128 1373 0.0 T 13-09-2016 THL1_RS10330 fd9a91dcff9afde35d115c2aa47fd5c8 1620 SUPERFAMILY SSF53223 760 946 5.85E-25 T 13-09-2016 THL1_RS10330 fd9a91dcff9afde35d115c2aa47fd5c8 1620 PANTHER PTHR11606:SF1 675 1103 0.0 T 13-09-2016 THL1_RS20635 cdd8ebcb437f42a6040dc2a2471fe365 220 SUPERFAMILY SSF48498 103 218 9.43E-23 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS20635 cdd8ebcb437f42a6040dc2a2471fe365 220 SUPERFAMILY SSF46689 26 97 3.28E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS20635 cdd8ebcb437f42a6040dc2a2471fe365 220 PANTHER PTHR30055:SF57 17 217 6.0E-33 T 13-09-2016 THL1_RS20635 cdd8ebcb437f42a6040dc2a2471fe365 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 77 1.7E-12 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20635 cdd8ebcb437f42a6040dc2a2471fe365 220 Pfam PF08359 YsiA-like protein, C-terminal region 92 211 8.7E-7 T 13-09-2016 IPR013570 Transcription regulator YsiA, C-terminal THL1_RS20635 cdd8ebcb437f42a6040dc2a2471fe365 220 Gene3D G3DSA:1.10.10.60 26 76 6.4E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS20635 cdd8ebcb437f42a6040dc2a2471fe365 220 PANTHER PTHR30055 17 217 6.0E-33 T 13-09-2016 THL1_RS20635 cdd8ebcb437f42a6040dc2a2471fe365 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 1.0E-7 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20635 cdd8ebcb437f42a6040dc2a2471fe365 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 1.0E-7 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20635 cdd8ebcb437f42a6040dc2a2471fe365 220 Gene3D G3DSA:1.10.357.10 77 219 2.0E-34 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS03420 8e98b51a77dffe552cb03c0a369cece1 318 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 1 313 31.614 T 13-09-2016 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 THL1_RS03420 8e98b51a77dffe552cb03c0a369cece1 318 PANTHER PTHR12835 1 314 2.2E-77 T 13-09-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 THL1_RS03420 8e98b51a77dffe552cb03c0a369cece1 318 Gene3D G3DSA:1.10.10.10 1 58 7.2E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS03420 8e98b51a77dffe552cb03c0a369cece1 318 Gene3D G3DSA:3.30.930.10 67 263 1.4E-62 T 13-09-2016 THL1_RS03420 8e98b51a77dffe552cb03c0a369cece1 318 Pfam PF02237 Biotin protein ligase C terminal domain 269 313 2.5E-6 T 13-09-2016 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15 THL1_RS03420 8e98b51a77dffe552cb03c0a369cece1 318 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 77 312 2.7E-56 T 13-09-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 THL1_RS03420 8e98b51a77dffe552cb03c0a369cece1 318 SUPERFAMILY SSF55681 69 263 1.35E-58 T 13-09-2016 THL1_RS03420 8e98b51a77dffe552cb03c0a369cece1 318 SUPERFAMILY SSF50037 267 313 1.42E-8 T 13-09-2016 IPR008988 Transcriptional repressor, C-terminal THL1_RS03420 8e98b51a77dffe552cb03c0a369cece1 318 SUPERFAMILY SSF46785 3 56 1.58E-9 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS03420 8e98b51a77dffe552cb03c0a369cece1 318 Gene3D G3DSA:2.30.30.100 267 315 8.1E-17 T 13-09-2016 THL1_RS03420 8e98b51a77dffe552cb03c0a369cece1 318 Pfam PF03099 Biotin/lipoate A/B protein ligase family 99 204 5.1E-17 T 13-09-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 THL1_RS03420 8e98b51a77dffe552cb03c0a369cece1 318 Pfam PF08279 HTH domain 3 54 4.5E-12 T 13-09-2016 IPR013196 Helix-turn-helix, type 11 THL1_RS05545 17e4162e3fb83bab86d23f48279aa6f0 403 SUPERFAMILY SSF81342 13 278 1.15E-95 T 13-09-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 THL1_RS05545 17e4162e3fb83bab86d23f48279aa6f0 403 Gene3D G3DSA:1.20.810.10 5 399 1.2E-162 T 13-09-2016 IPR027387 Cytochrome b/b6-like domain THL1_RS05545 17e4162e3fb83bab86d23f48279aa6f0 403 SUPERFAMILY SSF81648 280 396 9.16E-34 T 13-09-2016 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 THL1_RS05545 17e4162e3fb83bab86d23f48279aa6f0 403 PIRSF PIRSF038885 1 403 2.8E-159 T 13-09-2016 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 THL1_RS05545 17e4162e3fb83bab86d23f48279aa6f0 403 PANTHER PTHR19271 1 401 1.4E-266 T 13-09-2016 THL1_RS05545 17e4162e3fb83bab86d23f48279aa6f0 403 Pfam PF00033 Cytochrome b/b6/petB 24 211 2.0E-66 T 13-09-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 THL1_RS05545 17e4162e3fb83bab86d23f48279aa6f0 403 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 277 379 9.3E-44 T 13-09-2016 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 THL1_RS05545 17e4162e3fb83bab86d23f48279aa6f0 403 PANTHER PTHR19271:SF9 1 401 1.4E-266 T 13-09-2016 THL1_RS26270 feec85ac49b2c627b608f3e9ce3a972b 355 PANTHER PTHR21091 1 355 1.9E-154 T 13-09-2016 THL1_RS26270 feec85ac49b2c627b608f3e9ce3a972b 355 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 5 348 7.5E-140 T 13-09-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS26270 feec85ac49b2c627b608f3e9ce3a972b 355 PANTHER PTHR21091:SF2 1 355 1.9E-154 T 13-09-2016 THL1_RS26270 feec85ac49b2c627b608f3e9ce3a972b 355 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 143 159 - T 13-09-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS26270 feec85ac49b2c627b608f3e9ce3a972b 355 SUPERFAMILY SSF51726 1 354 7.06E-124 T 13-09-2016 THL1_RS26270 feec85ac49b2c627b608f3e9ce3a972b 355 Gene3D G3DSA:3.20.20.210 4 354 6.0E-154 T 13-09-2016 THL1_RS26270 feec85ac49b2c627b608f3e9ce3a972b 355 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 9 348 9.2E-134 T 13-09-2016 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS26270 feec85ac49b2c627b608f3e9ce3a972b 355 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 6 350 49.272 T 13-09-2016 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS26270 feec85ac49b2c627b608f3e9ce3a972b 355 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 22 31 - T 13-09-2016 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS13050 bac34f73a0755e93162bf14d9266f292 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.9E-7 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS13050 bac34f73a0755e93162bf14d9266f292 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.9E-7 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS13050 bac34f73a0755e93162bf14d9266f292 226 PANTHER PTHR30055:SF71 1 143 7.6E-17 T 13-09-2016 THL1_RS13050 bac34f73a0755e93162bf14d9266f292 226 Gene3D G3DSA:1.10.357.10 10 174 2.2E-18 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS13050 bac34f73a0755e93162bf14d9266f292 226 SUPERFAMILY SSF46689 8 78 2.82E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13050 bac34f73a0755e93162bf14d9266f292 226 PANTHER PTHR30055 1 143 7.6E-17 T 13-09-2016 THL1_RS13050 bac34f73a0755e93162bf14d9266f292 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 6.1E-9 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS27225 649c07e137972a07145eeb9d2a218e07 360 Gene3D G3DSA:3.30.1360.120 3 53 1.5E-50 T 13-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THL1_RS27225 649c07e137972a07145eeb9d2a218e07 360 Gene3D G3DSA:3.30.1360.120 143 230 1.5E-50 T 13-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THL1_RS27225 649c07e137972a07145eeb9d2a218e07 360 SUPERFAMILY SSF103025 3 277 2.67E-87 T 13-09-2016 THL1_RS27225 649c07e137972a07145eeb9d2a218e07 360 Pfam PF01571 Aminomethyltransferase folate-binding domain 7 252 1.4E-81 T 13-09-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal THL1_RS27225 649c07e137972a07145eeb9d2a218e07 360 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 355 9.8E-126 T 13-09-2016 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS27225 649c07e137972a07145eeb9d2a218e07 360 PANTHER PTHR13847:SF5 5 341 1.2E-60 T 13-09-2016 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS27225 649c07e137972a07145eeb9d2a218e07 360 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 355 43.299 T 13-09-2016 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS27225 649c07e137972a07145eeb9d2a218e07 360 SUPERFAMILY SSF101790 270 357 1.8E-25 T 13-09-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain THL1_RS27225 649c07e137972a07145eeb9d2a218e07 360 PIRSF PIRSF006487 1 358 1.0E-80 T 13-09-2016 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS27225 649c07e137972a07145eeb9d2a218e07 360 PANTHER PTHR13847 5 341 1.2E-60 T 13-09-2016 THL1_RS27225 649c07e137972a07145eeb9d2a218e07 360 Gene3D G3DSA:2.40.30.110 279 357 9.3E-28 T 13-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS27225 649c07e137972a07145eeb9d2a218e07 360 Gene3D G3DSA:3.30.70.1400 54 136 8.4E-30 T 13-09-2016 THL1_RS27225 649c07e137972a07145eeb9d2a218e07 360 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 261 349 9.8E-21 T 13-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS21780 ed5ad65139e2ca3e008998ab16b8ee26 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.0E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21780 ed5ad65139e2ca3e008998ab16b8ee26 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.0E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21780 ed5ad65139e2ca3e008998ab16b8ee26 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.0E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21780 ed5ad65139e2ca3e008998ab16b8ee26 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.0E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21780 ed5ad65139e2ca3e008998ab16b8ee26 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.0E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21780 ed5ad65139e2ca3e008998ab16b8ee26 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.0E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21780 ed5ad65139e2ca3e008998ab16b8ee26 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS21780 ed5ad65139e2ca3e008998ab16b8ee26 257 Gene3D G3DSA:3.40.50.720 2 248 2.5E-84 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS21780 ed5ad65139e2ca3e008998ab16b8ee26 257 PANTHER PTHR24321 2 248 4.4E-60 T 13-09-2016 THL1_RS21780 ed5ad65139e2ca3e008998ab16b8ee26 257 PANTHER PTHR24321:SF6 2 248 4.4E-60 T 13-09-2016 THL1_RS21780 ed5ad65139e2ca3e008998ab16b8ee26 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.6E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21780 ed5ad65139e2ca3e008998ab16b8ee26 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 8.6E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21780 ed5ad65139e2ca3e008998ab16b8ee26 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.6E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21780 ed5ad65139e2ca3e008998ab16b8ee26 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 247 7.0E-74 T 13-09-2016 THL1_RS21780 ed5ad65139e2ca3e008998ab16b8ee26 257 SUPERFAMILY SSF51735 6 248 2.93E-79 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10845 ac2d88d808bd632348052ad618f67823 428 PANTHER PTHR11739 34 427 5.8E-205 T 13-09-2016 IPR002020 Citrate synthase GO:0046912 THL1_RS10845 ac2d88d808bd632348052ad618f67823 428 ProSitePatterns PS00480 Citrate synthase signature. 303 315 - T 13-09-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 UniPathway: UPA00223 THL1_RS10845 ac2d88d808bd632348052ad618f67823 428 Gene3D G3DSA:1.10.230.10 281 373 2.9E-41 T 13-09-2016 IPR016143 Citrate synthase-like, small alpha subdomain THL1_RS10845 ac2d88d808bd632348052ad618f67823 428 Gene3D G3DSA:1.10.580.10 52 280 9.9E-100 T 13-09-2016 IPR016142 Citrate synthase-like, large alpha subdomain UniPathway: UPA00223 THL1_RS10845 ac2d88d808bd632348052ad618f67823 428 SUPERFAMILY SSF48256 6 427 1.11E-169 T 13-09-2016 IPR002020 Citrate synthase GO:0046912 THL1_RS10845 ac2d88d808bd632348052ad618f67823 428 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 16 421 2.4E-237 T 13-09-2016 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 UniPathway: UPA00223 THL1_RS10845 ac2d88d808bd632348052ad618f67823 428 PRINTS PR00143 Citrate synthase signature 379 393 1.7E-56 T 13-09-2016 IPR002020 Citrate synthase GO:0046912 THL1_RS10845 ac2d88d808bd632348052ad618f67823 428 PRINTS PR00143 Citrate synthase signature 219 234 1.7E-56 T 13-09-2016 IPR002020 Citrate synthase GO:0046912 THL1_RS10845 ac2d88d808bd632348052ad618f67823 428 PRINTS PR00143 Citrate synthase signature 165 178 1.7E-56 T 13-09-2016 IPR002020 Citrate synthase GO:0046912 THL1_RS10845 ac2d88d808bd632348052ad618f67823 428 PRINTS PR00143 Citrate synthase signature 296 316 1.7E-56 T 13-09-2016 IPR002020 Citrate synthase GO:0046912 THL1_RS10845 ac2d88d808bd632348052ad618f67823 428 PRINTS PR00143 Citrate synthase signature 359 375 1.7E-56 T 13-09-2016 IPR002020 Citrate synthase GO:0046912 THL1_RS10845 ac2d88d808bd632348052ad618f67823 428 PRINTS PR00143 Citrate synthase signature 241 269 1.7E-56 T 13-09-2016 IPR002020 Citrate synthase GO:0046912 THL1_RS10845 ac2d88d808bd632348052ad618f67823 428 PIRSF PIRSF001369 38 428 1.0E-178 T 13-09-2016 IPR024176 Citrate synthase, bacterial-type UniPathway: UPA00223 THL1_RS10845 ac2d88d808bd632348052ad618f67823 428 Pfam PF00285 Citrate synthase, C-terminal domain 46 410 6.7E-134 T 13-09-2016 IPR002020 Citrate synthase GO:0046912 THL1_RS12685 22fa0432c9b905940e236d494bc2df4e 572 Pfam PF00890 FAD binding domain 18 550 9.8E-97 T 13-09-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain THL1_RS12685 22fa0432c9b905940e236d494bc2df4e 572 PANTHER PTHR11632 213 566 3.7E-154 T 13-09-2016 THL1_RS12685 22fa0432c9b905940e236d494bc2df4e 572 Gene3D G3DSA:3.90.700.10 351 499 3.2E-31 T 13-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain THL1_RS12685 22fa0432c9b905940e236d494bc2df4e 572 Gene3D G3DSA:3.50.50.60 10 150 8.4E-59 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12685 22fa0432c9b905940e236d494bc2df4e 572 Gene3D G3DSA:3.50.50.60 218 324 8.4E-59 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12685 22fa0432c9b905940e236d494bc2df4e 572 Gene3D G3DSA:3.50.50.60 505 568 8.4E-59 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12685 22fa0432c9b905940e236d494bc2df4e 572 SUPERFAMILY SSF51905 16 291 4.97E-35 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12685 22fa0432c9b905940e236d494bc2df4e 572 SUPERFAMILY SSF51905 503 545 4.97E-35 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12685 22fa0432c9b905940e236d494bc2df4e 572 SUPERFAMILY SSF56425 350 504 2.89E-32 T 13-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain THL1_RS12685 22fa0432c9b905940e236d494bc2df4e 572 PANTHER PTHR11632:SF59 213 566 3.7E-154 T 13-09-2016 THL1_RS12685 22fa0432c9b905940e236d494bc2df4e 572 PANTHER PTHR11632:SF59 16 141 3.7E-154 T 13-09-2016 THL1_RS12685 22fa0432c9b905940e236d494bc2df4e 572 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 525 540 1.9E-5 T 13-09-2016 THL1_RS12685 22fa0432c9b905940e236d494bc2df4e 572 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 18 40 1.9E-5 T 13-09-2016 THL1_RS12685 22fa0432c9b905940e236d494bc2df4e 572 PANTHER PTHR11632 16 141 3.7E-154 T 13-09-2016 THL1_RS04885 8cb53f59c99fc55b0c24a35b218b44cd 127 PRINTS PR00813 Bacterial general secretion pathway protein G signature 8 33 3.5E-9 T 13-09-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THL1_RS04885 8cb53f59c99fc55b0c24a35b218b44cd 127 PRINTS PR00813 Bacterial general secretion pathway protein G signature 44 62 3.5E-9 T 13-09-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THL1_RS04885 8cb53f59c99fc55b0c24a35b218b44cd 127 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 30 110 1.7E-15 T 13-09-2016 IPR031982 Type IV minor pilin ComP THL1_RS04885 8cb53f59c99fc55b0c24a35b218b44cd 127 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 29 1.3E-11 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS04885 8cb53f59c99fc55b0c24a35b218b44cd 127 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 7 27 - T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS04885 8cb53f59c99fc55b0c24a35b218b44cd 127 PANTHER PTHR30093 3 67 7.9E-28 T 13-09-2016 THL1_RS04885 8cb53f59c99fc55b0c24a35b218b44cd 127 Gene3D G3DSA:3.30.700.10 9 111 4.2E-22 T 13-09-2016 THL1_RS04885 8cb53f59c99fc55b0c24a35b218b44cd 127 PANTHER PTHR30093:SF4 3 67 7.9E-28 T 13-09-2016 THL1_RS04885 8cb53f59c99fc55b0c24a35b218b44cd 127 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 4 28 1.0E-9 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS04885 8cb53f59c99fc55b0c24a35b218b44cd 127 SUPERFAMILY SSF54523 9 122 3.09E-23 T 13-09-2016 THL1_RS04380 8d1ce71b2aef95f3b3894aa62408b7a2 188 PANTHER PTHR21600 129 184 1.2E-85 T 13-09-2016 THL1_RS04380 8d1ce71b2aef95f3b3894aa62408b7a2 188 SUPERFAMILY SSF55120 9 187 1.02E-43 T 13-09-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS04380 8d1ce71b2aef95f3b3894aa62408b7a2 188 Pfam PF00849 RNA pseudouridylate synthase 12 155 5.3E-16 T 13-09-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS04380 8d1ce71b2aef95f3b3894aa62408b7a2 188 PANTHER PTHR21600:SF23 129 184 1.2E-85 T 13-09-2016 THL1_RS04380 8d1ce71b2aef95f3b3894aa62408b7a2 188 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 15 184 3.9E-57 T 13-09-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 THL1_RS04380 8d1ce71b2aef95f3b3894aa62408b7a2 188 PANTHER PTHR21600 8 112 1.2E-85 T 13-09-2016 THL1_RS04380 8d1ce71b2aef95f3b3894aa62408b7a2 188 PANTHER PTHR21600:SF23 8 112 1.2E-85 T 13-09-2016 THL1_RS04380 8d1ce71b2aef95f3b3894aa62408b7a2 188 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 46 60 - T 13-09-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 THL1_RS03855 08e0e7979565b2386c77ee4334e5c28e 364 PANTHER PTHR21327:SF6 1 364 1.3E-146 T 13-09-2016 THL1_RS03855 08e0e7979565b2386c77ee4334e5c28e 364 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 3 199 2.2E-71 T 13-09-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS03855 08e0e7979565b2386c77ee4334e5c28e 364 PANTHER PTHR21327 1 364 1.3E-146 T 13-09-2016 THL1_RS03855 08e0e7979565b2386c77ee4334e5c28e 364 SUPERFAMILY SSF55821 2 202 5.72E-84 T 13-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain THL1_RS03855 08e0e7979565b2386c77ee4334e5c28e 364 Pfam PF00925 GTP cyclohydrolase II 208 362 3.0E-30 T 13-09-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 THL1_RS03855 08e0e7979565b2386c77ee4334e5c28e 364 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 8 198 4.8E-81 T 13-09-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS03855 08e0e7979565b2386c77ee4334e5c28e 364 Gene3D G3DSA:3.90.870.10 1 211 4.0E-96 T 13-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain THL1_RS03855 08e0e7979565b2386c77ee4334e5c28e 364 SUPERFAMILY SSF142695 204 362 4.05E-41 T 13-09-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 THL1_RS03855 08e0e7979565b2386c77ee4334e5c28e 364 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 37.441 T 13-09-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS03855 08e0e7979565b2386c77ee4334e5c28e 364 PIRSF PIRSF001259 1 364 3.5E-114 T 13-09-2016 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2461 2472 27.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3529 3545 21.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3420 3435 0.0041 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3649 3664 0.29 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3511 3527 0.48 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2419 2433 26.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2398 2415 0.26 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 947 963 19.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3138 3154 0.072 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3402 3418 2.5 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2383 2397 0.22 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3326 3343 5.2 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 973 983 48.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3613 3629 1.8 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3630 3647 0.0051 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3720 3737 0.018 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3040 3055 0.34 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3209 3226 0.024 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3738 3755 0.028 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 931 945 3.1 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3121 3137 1.6 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 910 927 23.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2647 2663 11.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3547 3562 8.1 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2434 2451 4.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3309 3325 0.46 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3056 3072 0.19 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1169 1185 8.3 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3228 3244 28.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3493 3509 0.98 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 895 909 2.5 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 PANTHER PTHR11475 1897 1938 5.4E-51 T 13-09-2016 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Gene3D G3DSA:2.150.10.10 3688 3833 3.6E-17 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Gene3D G3DSA:2.150.10.10 879 1006 1.2E-17 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Gene3D G3DSA:2.150.10.10 2354 2456 2.0E-18 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Gene3D G3DSA:2.150.10.10 3401 3581 2.7E-27 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Gene3D G3DSA:2.150.10.10 3037 3112 8.6E-11 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Gene3D G3DSA:2.150.10.10 3582 3687 4.7E-16 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Gene3D G3DSA:2.150.10.10 3113 3284 4.8E-22 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Gene3D G3DSA:2.150.10.10 2461 2550 8.6E-11 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Gene3D G3DSA:2.150.10.10 2647 2671 8.6E-11 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Gene3D G3DSA:2.150.10.10 3285 3396 2.9E-15 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF51120 3401 3473 1.92E-11 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3323 3341 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 PANTHER PTHR11475:SF4 1897 1938 5.4E-51 T 13-09-2016 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2386 2404 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF51120 3115 3286 2.41E-25 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3516 3534 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3044 3062 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 907 925 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3636 3654 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 PRINTS PR00313 NodO calcium binding signature 2408 2416 3.2E-6 T 13-09-2016 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 PRINTS PR00313 NodO calcium binding signature 2387 2398 3.2E-6 T 13-09-2016 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 PRINTS PR00313 NodO calcium binding signature 2426 2434 3.2E-6 T 13-09-2016 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 PRINTS PR00313 NodO calcium binding signature 2444 2453 3.2E-6 T 13-09-2016 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF51120 3679 3819 9.16E-18 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3507 3525 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF51120 2362 2553 4.97E-16 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF03098 Animal haem peroxidase 1901 2290 1.4E-60 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF03098 Animal haem peroxidase 420 821 4.3E-53 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF03098 Animal haem peroxidase 1502 1738 9.3E-10 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Pfam PF03098 Animal haem peroxidase 42 264 5.5E-11 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3726 3744 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3215 3233 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 PANTHER PTHR11475:SF4 2206 2293 5.4E-51 T 13-09-2016 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 PANTHER PTHR11475:SF4 194 291 5.4E-51 T 13-09-2016 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2431 2449 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3305 3323 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF51120 1022 1118 7.2E-7 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF51120 1157 1266 7.2E-7 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2413 2431 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF51120 3454 3605 1.62E-13 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 PANTHER PTHR11475:SF4 2162 2178 5.4E-51 T 13-09-2016 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF51120 3269 3398 1.15E-17 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2422 2440 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 898 916 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3416 3434 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3735 3753 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF51120 872 1010 9.68E-15 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 PANTHER PTHR11475 2206 2293 5.4E-51 T 13-09-2016 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 PANTHER PTHR11475 194 291 5.4E-51 T 13-09-2016 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3135 3153 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3314 3332 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 PANTHER PTHR11475 2162 2178 5.4E-51 T 13-09-2016 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF48113 741 825 9.59E-112 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF48113 420 464 9.59E-112 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF48113 38 118 9.59E-112 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF48113 162 292 9.59E-112 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF48113 494 693 9.59E-112 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Gene3D G3DSA:1.10.640.10 741 825 6.3E-130 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Gene3D G3DSA:1.10.640.10 328 345 6.3E-130 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Gene3D G3DSA:1.10.640.10 179 269 6.3E-130 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Gene3D G3DSA:1.10.640.10 407 693 6.3E-130 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Gene3D G3DSA:1.10.640.10 1653 1739 1.0E-122 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Gene3D G3DSA:1.10.640.10 2210 2294 1.0E-122 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 Gene3D G3DSA:1.10.640.10 1852 2161 1.0E-122 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2395 2413 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3525 3543 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3627 3645 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 PANTHER PTHR11475 1955 2142 5.4E-51 T 13-09-2016 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF48113 1884 2161 6.06E-113 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF48113 2210 2295 6.06E-113 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF48113 1636 1758 6.06E-113 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF48113 1499 1579 6.06E-113 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3534 3552 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 PANTHER PTHR11475:SF4 1955 2142 5.4E-51 T 13-09-2016 THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF51120 3007 3129 7.33E-13 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19880 24268f68d3066a14bdf849ef54629e9c 3835 SUPERFAMILY SSF51120 3538 3686 3.44E-22 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS00165 599a2a2989afe8aed833920999adfdd5 269 PANTHER PTHR10314 74 130 9.4E-22 T 13-09-2016 THL1_RS00165 599a2a2989afe8aed833920999adfdd5 269 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 260 3.7E-80 T 13-09-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 THL1_RS00165 599a2a2989afe8aed833920999adfdd5 269 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 263 36.596 T 13-09-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 THL1_RS00165 599a2a2989afe8aed833920999adfdd5 269 Gene3D G3DSA:3.20.20.70 3 265 1.1E-102 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS00165 599a2a2989afe8aed833920999adfdd5 269 Pfam PF00290 Tryptophan synthase alpha chain 8 262 6.0E-100 T 13-09-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 THL1_RS00165 599a2a2989afe8aed833920999adfdd5 269 PANTHER PTHR10314:SF4 74 130 9.4E-22 T 13-09-2016 THL1_RS00165 599a2a2989afe8aed833920999adfdd5 269 SUPERFAMILY SSF51366 1 243 4.99E-91 T 13-09-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 THL1_RS00165 599a2a2989afe8aed833920999adfdd5 269 PANTHER PTHR10314:SF4 1 51 9.4E-22 T 13-09-2016 THL1_RS00165 599a2a2989afe8aed833920999adfdd5 269 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 13-09-2016 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 THL1_RS00165 599a2a2989afe8aed833920999adfdd5 269 PANTHER PTHR10314 1 51 9.4E-22 T 13-09-2016 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 SUPERFAMILY SSF82693 138 184 8.02E-30 T 13-09-2016 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 SUPERFAMILY SSF82693 277 333 8.02E-30 T 13-09-2016 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 Gene3D G3DSA:3.30.2090.10 735 823 6.0E-24 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 Gene3D G3DSA:3.30.2090.10 184 277 2.8E-27 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 SUPERFAMILY SSF82693 576 682 2.88E-28 T 13-09-2016 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 SUPERFAMILY SSF82714 185 274 4.45E-21 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 SUPERFAMILY SSF82714 735 820 2.62E-21 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 PANTHER PTHR32063:SF11 1 1052 0.0 T 13-09-2016 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.8E-93 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 1.8E-93 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 1.8E-93 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.8E-93 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 1.8E-93 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 PRINTS PR00702 Acriflavin resistance protein family signature 563 580 1.8E-93 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 PRINTS PR00702 Acriflavin resistance protein family signature 632 646 1.8E-93 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 1.8E-93 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 1.8E-93 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 Pfam PF00873 AcrB/AcrD/AcrF family 3 1040 0.0 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 Gene3D G3DSA:3.30.70.1430 41 141 5.3E-30 T 13-09-2016 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 Gene3D G3DSA:3.30.70.1430 580 682 2.3E-31 T 13-09-2016 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1052 0.0 T 13-09-2016 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 SUPERFAMILY SSF82693 41 134 8.11E-25 T 13-09-2016 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 PANTHER PTHR32063 1 1052 0.0 T 13-09-2016 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 Gene3D G3DSA:1.10.3850.10 827 1039 1.5E-56 T 13-09-2016 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 Gene3D G3DSA:1.10.3850.10 285 500 1.3E-62 T 13-09-2016 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 SUPERFAMILY SSF82693 821 870 1.92E-25 T 13-09-2016 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 SUPERFAMILY SSF82693 683 734 1.92E-25 T 13-09-2016 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 SUPERFAMILY SSF82866 844 1039 2.88E-44 T 13-09-2016 THL1_RS12025 0446a4a1ff34db2e47bd6c974a77e3b8 1062 SUPERFAMILY SSF82866 299 499 6.15E-52 T 13-09-2016 THL1_RS22695 d80795af48bfbf5bb00764c7f44d880f 380 Pfam PF07687 Peptidase dimerisation domain 179 286 8.3E-27 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS22695 d80795af48bfbf5bb00764c7f44d880f 380 Gene3D G3DSA:3.40.630.10 320 378 1.3E-71 T 13-09-2016 THL1_RS22695 d80795af48bfbf5bb00764c7f44d880f 380 Gene3D G3DSA:3.40.630.10 7 191 1.3E-71 T 13-09-2016 THL1_RS22695 d80795af48bfbf5bb00764c7f44d880f 380 SUPERFAMILY SSF53187 6 182 7.38E-65 T 13-09-2016 THL1_RS22695 d80795af48bfbf5bb00764c7f44d880f 380 SUPERFAMILY SSF53187 296 378 7.38E-65 T 13-09-2016 THL1_RS22695 d80795af48bfbf5bb00764c7f44d880f 380 Gene3D G3DSA:3.30.70.360 192 292 5.9E-35 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS22695 d80795af48bfbf5bb00764c7f44d880f 380 PANTHER PTHR11014:SF106 6 380 2.0E-93 T 13-09-2016 THL1_RS22695 d80795af48bfbf5bb00764c7f44d880f 380 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 8 377 5.8E-165 T 13-09-2016 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18|UniPathway: UPA00034 THL1_RS22695 d80795af48bfbf5bb00764c7f44d880f 380 PANTHER PTHR11014 6 380 2.0E-93 T 13-09-2016 THL1_RS22695 d80795af48bfbf5bb00764c7f44d880f 380 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 5 379 52.485 T 13-09-2016 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18|UniPathway: UPA00034 THL1_RS22695 d80795af48bfbf5bb00764c7f44d880f 380 Pfam PF01546 Peptidase family M20/M25/M40 65 375 1.5E-40 T 13-09-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 THL1_RS22695 d80795af48bfbf5bb00764c7f44d880f 380 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 101 139 - T 13-09-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 THL1_RS22695 d80795af48bfbf5bb00764c7f44d880f 380 SUPERFAMILY SSF55031 183 292 1.12E-29 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS11130 e057b971b51f0bd08cedb7ba19b5efc9 344 SUPERFAMILY SSF53474 225 342 3.64E-42 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS11130 e057b971b51f0bd08cedb7ba19b5efc9 344 SUPERFAMILY SSF53474 30 175 3.64E-42 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS11130 e057b971b51f0bd08cedb7ba19b5efc9 344 Pfam PF01738 Dienelactone hydrolase family 60 212 3.5E-8 T 13-09-2016 IPR002925 Dienelactone hydrolase GO:0016787 THL1_RS11130 e057b971b51f0bd08cedb7ba19b5efc9 344 Gene3D G3DSA:3.40.50.1820 38 342 1.0E-68 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS11130 e057b971b51f0bd08cedb7ba19b5efc9 344 PANTHER PTHR17630 22 344 3.3E-90 T 13-09-2016 THL1_RS11130 e057b971b51f0bd08cedb7ba19b5efc9 344 PANTHER PTHR17630:SF49 22 344 3.3E-90 T 13-09-2016 THL1_RS15535 6ca78dffcfd22afcbd29470ae55f401a 331 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 293 308 8.4E-6 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS15535 6ca78dffcfd22afcbd29470ae55f401a 331 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 308 324 8.4E-6 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS15535 6ca78dffcfd22afcbd29470ae55f401a 331 PANTHER PTHR11019:SF52 224 331 4.2E-29 T 13-09-2016 THL1_RS15535 6ca78dffcfd22afcbd29470ae55f401a 331 Pfam PF12833 Helix-turn-helix domain 248 325 4.2E-20 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS15535 6ca78dffcfd22afcbd29470ae55f401a 331 SMART SM00342 242 324 1.3E-27 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS15535 6ca78dffcfd22afcbd29470ae55f401a 331 SUPERFAMILY SSF46689 277 326 2.91E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15535 6ca78dffcfd22afcbd29470ae55f401a 331 Gene3D G3DSA:1.10.10.60 251 268 3.3E-4 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15535 6ca78dffcfd22afcbd29470ae55f401a 331 Gene3D G3DSA:1.10.10.60 277 328 8.4E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15535 6ca78dffcfd22afcbd29470ae55f401a 331 PANTHER PTHR11019 224 331 4.2E-29 T 13-09-2016 THL1_RS15535 6ca78dffcfd22afcbd29470ae55f401a 331 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 21 198 2.7E-32 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS12920 00d95e5dfc66519bea7e1d86f34c4ad5 360 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 11 318 2.0E-43 T 13-09-2016 THL1_RS12920 00d95e5dfc66519bea7e1d86f34c4ad5 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 289 1.0E-11 T 13-09-2016 THL1_RS12920 00d95e5dfc66519bea7e1d86f34c4ad5 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 1.0E-11 T 13-09-2016 THL1_RS12920 00d95e5dfc66519bea7e1d86f34c4ad5 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 1.0E-11 T 13-09-2016 THL1_RS12920 00d95e5dfc66519bea7e1d86f34c4ad5 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 125 143 1.0E-11 T 13-09-2016 THL1_RS12920 00d95e5dfc66519bea7e1d86f34c4ad5 360 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 1.0E-11 T 13-09-2016 THL1_RS12920 00d95e5dfc66519bea7e1d86f34c4ad5 360 PANTHER PTHR23023 5 322 1.1E-93 T 13-09-2016 THL1_RS12920 00d95e5dfc66519bea7e1d86f34c4ad5 360 Gene3D G3DSA:3.50.50.60 9 182 6.7E-52 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12920 00d95e5dfc66519bea7e1d86f34c4ad5 360 Gene3D G3DSA:3.50.50.60 183 318 1.7E-8 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12920 00d95e5dfc66519bea7e1d86f34c4ad5 360 SUPERFAMILY SSF51905 167 319 1.81E-10 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12920 00d95e5dfc66519bea7e1d86f34c4ad5 360 SUPERFAMILY SSF51905 7 228 3.39E-53 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12920 00d95e5dfc66519bea7e1d86f34c4ad5 360 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 165 189 1.4E-16 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS12920 00d95e5dfc66519bea7e1d86f34c4ad5 360 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 309 327 1.4E-16 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS12920 00d95e5dfc66519bea7e1d86f34c4ad5 360 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 1.4E-16 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS12920 00d95e5dfc66519bea7e1d86f34c4ad5 360 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 134 1.4E-16 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 PIRSF PIRSF006485 1 460 3.7E-172 T 13-09-2016 IPR016484 GTP-binding protein EngA GO:0005525 THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 Pfam PF01926 50S ribosome-binding GTPase 198 316 2.5E-24 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 Pfam PF01926 50S ribosome-binding GTPase 5 119 1.7E-28 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 PANTHER PTHR11649 1 452 1.3E-149 T 13-09-2016 THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 372 452 4.6E-27 T 13-09-2016 IPR032859 GTPase Der, C-terminal KH-domain-like THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 SUPERFAMILY SSF52540 4 168 2.18E-45 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 PANTHER PTHR11649:SF5 1 452 1.3E-149 T 13-09-2016 IPR016484 GTP-binding protein EngA GO:0005525 THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 452 1.4E-175 T 13-09-2016 IPR016484 GTP-binding protein EngA GO:0005525 THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 Gene3D G3DSA:3.40.50.300 3 167 3.4E-47 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 Gene3D G3DSA:3.40.50.300 193 379 1.1E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 SUPERFAMILY SSF52540 137 166 8.05E-65 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 SUPERFAMILY SSF52540 194 458 8.05E-65 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 Hamap MF_00195 GTPase Der [der]. 2 455 38.3 T 13-09-2016 IPR016484 GTP-binding protein EngA GO:0005525 THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 4.2E-10 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 72 90 4.2E-10 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 154 1.0E-21 T 13-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 196 362 2.0E-23 T 13-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 THL1_RS06005 abdb1572b588134e0c26ee220b94de00 492 Gene3D G3DSA:3.30.300.20 380 453 5.5E-23 T 13-09-2016 IPR015946 K homology domain-like, alpha/beta THL1_RS10095 fd97b477223f1555b050b0fe7a470b05 205 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 4 205 42.685 T 13-09-2016 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24|UniPathway: UPA00035 THL1_RS10095 fd97b477223f1555b050b0fe7a470b05 205 PANTHER PTHR22854 4 205 3.9E-70 T 13-09-2016 THL1_RS10095 fd97b477223f1555b050b0fe7a470b05 205 PANTHER PTHR22854:SF6 4 205 3.9E-70 T 13-09-2016 THL1_RS10095 fd97b477223f1555b050b0fe7a470b05 205 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 6 201 9.0E-49 T 13-09-2016 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24|UniPathway: UPA00035 THL1_RS10095 fd97b477223f1555b050b0fe7a470b05 205 SUPERFAMILY SSF51366 5 203 4.24E-62 T 13-09-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 THL1_RS10095 fd97b477223f1555b050b0fe7a470b05 205 Gene3D G3DSA:3.20.20.70 4 204 1.4E-72 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS13865 5cec53984101024b491b95fadab4a8bb 494 PANTHER PTHR16943 1 494 1.2E-238 T 13-09-2016 IPR005656 MmgE/PrpD GO:0016829 THL1_RS13865 5cec53984101024b491b95fadab4a8bb 494 Pfam PF03972 MmgE/PrpD family 18 477 1.0E-148 T 13-09-2016 IPR005656 MmgE/PrpD GO:0016829 THL1_RS13865 5cec53984101024b491b95fadab4a8bb 494 PANTHER PTHR16943:SF19 1 494 1.2E-238 T 13-09-2016 THL1_RS13865 5cec53984101024b491b95fadab4a8bb 494 SUPERFAMILY SSF103378 13 493 7.85E-145 T 13-09-2016 IPR005656 MmgE/PrpD GO:0016829 THL1_RS13865 5cec53984101024b491b95fadab4a8bb 494 Gene3D G3DSA:3.30.1330.120 300 437 4.5E-50 T 13-09-2016 THL1_RS13865 5cec53984101024b491b95fadab4a8bb 494 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 14 494 6.8E-251 T 13-09-2016 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79|UniPathway: UPA00946 THL1_RS13615 3128ce690636981fd18894534d17a6b6 427 SUPERFAMILY SSF103473 23 426 5.1E-76 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS13615 3128ce690636981fd18894534d17a6b6 427 ProSitePatterns PS00217 Sugar transport proteins signature 2. 128 153 - T 13-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 THL1_RS13615 3128ce690636981fd18894534d17a6b6 427 Gene3D G3DSA:1.20.1250.20 30 220 1.0E-36 T 13-09-2016 THL1_RS13615 3128ce690636981fd18894534d17a6b6 427 Pfam PF07690 Major Facilitator Superfamily 39 293 1.8E-32 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS13615 3128ce690636981fd18894534d17a6b6 427 PANTHER PTHR23508:SF18 12 426 1.2E-209 T 13-09-2016 THL1_RS13615 3128ce690636981fd18894534d17a6b6 427 PANTHER PTHR23508 12 426 1.2E-209 T 13-09-2016 THL1_RS13615 3128ce690636981fd18894534d17a6b6 427 Gene3D G3DSA:1.20.1250.20 244 425 1.4E-20 T 13-09-2016 THL1_RS17250 69b699c5b69d61f1a7bb06d94c4e9ae0 193 Gene3D G3DSA:1.10.357.10 3 188 4.7E-30 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS17250 69b699c5b69d61f1a7bb06d94c4e9ae0 193 PANTHER PTHR30055 6 191 1.2E-20 T 13-09-2016 THL1_RS17250 69b699c5b69d61f1a7bb06d94c4e9ae0 193 SUPERFAMILY SSF46689 6 80 5.13E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17250 69b699c5b69d61f1a7bb06d94c4e9ae0 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 3.6E-10 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS05900 e017ab1d050b1f6cf6ad34731ec165fe 304 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 34 277 2.6E-80 T 13-09-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 THL1_RS05900 e017ab1d050b1f6cf6ad34731ec165fe 304 Gene3D G3DSA:1.20.1640.10 114 283 7.8E-28 T 13-09-2016 THL1_RS05900 e017ab1d050b1f6cf6ad34731ec165fe 304 Pfam PF02355 Protein export membrane protein 101 285 2.4E-67 T 13-09-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial THL1_RS05900 e017ab1d050b1f6cf6ad34731ec165fe 304 PRINTS PR01755 Bacterial translocase SecF protein signature 33 48 8.5E-32 T 13-09-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THL1_RS05900 e017ab1d050b1f6cf6ad34731ec165fe 304 PRINTS PR01755 Bacterial translocase SecF protein signature 193 211 8.5E-32 T 13-09-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THL1_RS05900 e017ab1d050b1f6cf6ad34731ec165fe 304 PRINTS PR01755 Bacterial translocase SecF protein signature 225 240 8.5E-32 T 13-09-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THL1_RS05900 e017ab1d050b1f6cf6ad34731ec165fe 304 PRINTS PR01755 Bacterial translocase SecF protein signature 145 159 8.5E-32 T 13-09-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THL1_RS05900 e017ab1d050b1f6cf6ad34731ec165fe 304 PANTHER PTHR30081 6 303 1.2E-83 T 13-09-2016 THL1_RS05900 e017ab1d050b1f6cf6ad34731ec165fe 304 Pfam PF07549 SecD/SecF GG Motif 29 55 4.3E-12 T 13-09-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site THL1_RS05900 e017ab1d050b1f6cf6ad34731ec165fe 304 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 6 288 28.405 T 13-09-2016 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 THL1_RS05900 e017ab1d050b1f6cf6ad34731ec165fe 304 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 90 274 2.8E-56 T 13-09-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THL1_RS05900 e017ab1d050b1f6cf6ad34731ec165fe 304 SUPERFAMILY SSF82866 69 284 1.26E-40 T 13-09-2016 THL1_RS12895 c4edc36268bef18e36927ccafda54988 229 Pfam PF00510 Cytochrome c oxidase subunit III 37 210 7.3E-12 T 13-09-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 THL1_RS12895 c4edc36268bef18e36927ccafda54988 229 PANTHER PTHR11403 50 212 1.5E-19 T 13-09-2016 IPR024791 Cytochrome c oxidase subunit III GO:0015002|GO:0016020|GO:0019646 THL1_RS12895 c4edc36268bef18e36927ccafda54988 229 Gene3D G3DSA:1.20.120.80 33 212 2.2E-33 T 13-09-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 THL1_RS12895 c4edc36268bef18e36927ccafda54988 229 SUPERFAMILY SSF81452 34 212 1.2E-33 T 13-09-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 THL1_RS27920 5230826b9c1a66c1538a33800983cd13 326 TIGRFAM TIGR02797 exbB: tonB-system energizer ExbB 98 307 2.1E-105 T 13-09-2016 IPR014164 TonB-system energizer ExbB type-1 GO:0006810|GO:0016020 THL1_RS27920 5230826b9c1a66c1538a33800983cd13 326 PANTHER PTHR30572 90 310 1.1E-69 T 13-09-2016 THL1_RS27920 5230826b9c1a66c1538a33800983cd13 326 PANTHER PTHR30572:SF11 90 310 1.1E-69 T 13-09-2016 THL1_RS27920 5230826b9c1a66c1538a33800983cd13 326 Pfam PF01618 MotA/TolQ/ExbB proton channel family 178 293 1.3E-35 T 13-09-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 THL1_RS20320 428d3e7b559d220d51657370860bc6bf 454 Pfam PF02417 Chromate transporter 262 446 8.4E-33 T 13-09-2016 IPR003370 Chromate transporter GO:0015109|GO:0015703 THL1_RS20320 428d3e7b559d220d51657370860bc6bf 454 Pfam PF02417 Chromate transporter 23 186 3.6E-36 T 13-09-2016 IPR003370 Chromate transporter GO:0015109|GO:0015703 THL1_RS20320 428d3e7b559d220d51657370860bc6bf 454 PIRSF PIRSF004810 4 453 5.6E-135 T 13-09-2016 IPR014047 Chromate transporter, long chain THL1_RS20320 428d3e7b559d220d51657370860bc6bf 454 PANTHER PTHR33567:SF1 24 454 4.0E-113 T 13-09-2016 THL1_RS20320 428d3e7b559d220d51657370860bc6bf 454 TIGRFAM TIGR00937 2A51: chromate efflux transporter 29 446 3.4E-71 T 13-09-2016 IPR014047 Chromate transporter, long chain THL1_RS20320 428d3e7b559d220d51657370860bc6bf 454 PANTHER PTHR33567 24 454 4.0E-113 T 13-09-2016 THL1_RS09445 084591e6d1e321d651ee0d9cc5f4a3dc 452 Gene3D G3DSA:3.20.20.140 70 392 3.6E-113 T 13-09-2016 THL1_RS09445 084591e6d1e321d651ee0d9cc5f4a3dc 452 PANTHER PTHR11271 4 450 4.2E-191 T 13-09-2016 THL1_RS09445 084591e6d1e321d651ee0d9cc5f4a3dc 452 Pfam PF01979 Amidohydrolase family 58 423 3.5E-64 T 13-09-2016 IPR006680 Amidohydrolase-related GO:0016787 THL1_RS09445 084591e6d1e321d651ee0d9cc5f4a3dc 452 Gene3D G3DSA:2.30.40.10 1 69 9.6E-18 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS09445 084591e6d1e321d651ee0d9cc5f4a3dc 452 PANTHER PTHR11271:SF37 4 450 4.2E-191 T 13-09-2016 THL1_RS09445 084591e6d1e321d651ee0d9cc5f4a3dc 452 SUPERFAMILY SSF51338 5 61 1.51E-25 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS09445 084591e6d1e321d651ee0d9cc5f4a3dc 452 SUPERFAMILY SSF51338 374 448 1.51E-25 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS09445 084591e6d1e321d651ee0d9cc5f4a3dc 452 SUPERFAMILY SSF51556 61 373 4.13E-99 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 Pfam PF05188 MutS domain II 119 244 2.5E-30 T 13-09-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 SMART SM00534 597 783 1.5E-121 T 13-09-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 PANTHER PTHR11361 1 786 0.0 T 13-09-2016 THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 Pfam PF00488 MutS domain V 600 786 3.2E-84 T 13-09-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 SUPERFAMILY SSF52540 559 786 1.45E-58 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 SMART SM00533 274 581 5.4E-109 T 13-09-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 Gene3D G3DSA:3.40.1170.10 1 111 8.9E-49 T 13-09-2016 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 SUPERFAMILY SSF48334 258 555 3.01E-86 T 13-09-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 Pfam PF05192 MutS domain III 261 549 4.6E-37 T 13-09-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 Pfam PF05190 MutS family domain IV 418 508 5.8E-29 T 13-09-2016 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 PANTHER PTHR11361:SF86 1 786 0.0 T 13-09-2016 THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 Gene3D G3DSA:3.40.50.300 559 786 7.1E-83 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 1 843 0.0 T 13-09-2016 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 678 694 - T 13-09-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 Gene3D G3DSA:3.30.420.110 117 247 1.4E-44 T 13-09-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 Gene3D G3DSA:1.10.1420.10 307 467 1.3E-54 T 13-09-2016 THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 SUPERFAMILY SSF53150 105 257 2.62E-43 T 13-09-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 1 838 24.8 T 13-09-2016 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 Pfam PF01624 MutS domain I 1 110 3.1E-41 T 13-09-2016 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 THL1_RS22470 8d16c66313d7fb83b41234819296e633 846 SUPERFAMILY SSF55271 1 106 4.32E-40 T 13-09-2016 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 THL1_RS05615 4f5a93cd3ea062eabdd9e2e00219efd7 487 Pfam PF02875 Mur ligase family, glutamate ligase domain 329 411 2.0E-23 T 13-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 THL1_RS05615 4f5a93cd3ea062eabdd9e2e00219efd7 487 Gene3D G3DSA:3.40.1390.10 7 95 5.4E-24 T 13-09-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05615 4f5a93cd3ea062eabdd9e2e00219efd7 487 SUPERFAMILY SSF53244 329 480 4.43E-47 T 13-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 THL1_RS05615 4f5a93cd3ea062eabdd9e2e00219efd7 487 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 18 479 1.4E-156 T 13-09-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 THL1_RS05615 4f5a93cd3ea062eabdd9e2e00219efd7 487 PANTHER PTHR23135:SF4 5 486 5.6E-202 T 13-09-2016 THL1_RS05615 4f5a93cd3ea062eabdd9e2e00219efd7 487 Gene3D G3DSA:3.40.1190.10 97 330 3.7E-83 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05615 4f5a93cd3ea062eabdd9e2e00219efd7 487 Pfam PF08245 Mur ligase middle domain 106 306 4.0E-52 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05615 4f5a93cd3ea062eabdd9e2e00219efd7 487 Gene3D G3DSA:3.90.190.20 331 471 4.8E-55 T 13-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 THL1_RS05615 4f5a93cd3ea062eabdd9e2e00219efd7 487 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 3 479 34.87 T 13-09-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 THL1_RS05615 4f5a93cd3ea062eabdd9e2e00219efd7 487 SUPERFAMILY SSF53623 97 326 1.57E-76 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05615 4f5a93cd3ea062eabdd9e2e00219efd7 487 SUPERFAMILY SSF63418 12 95 1.15E-18 T 13-09-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05615 4f5a93cd3ea062eabdd9e2e00219efd7 487 PANTHER PTHR23135 5 486 5.6E-202 T 13-09-2016 THL1_RS05615 4f5a93cd3ea062eabdd9e2e00219efd7 487 Pfam PF01225 Mur ligase family, catalytic domain 18 94 3.5E-11 T 13-09-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS01605 ea17ab649bee8414fd261decf57e3584 469 SUPERFAMILY SSF52283 10 198 1.42E-107 T 13-09-2016 THL1_RS01605 ea17ab649bee8414fd261decf57e3584 469 SUPERFAMILY SSF52283 382 469 1.42E-107 T 13-09-2016 THL1_RS01605 ea17ab649bee8414fd261decf57e3584 469 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 199 381 2.4E-56 T 13-09-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 THL1_RS01605 ea17ab649bee8414fd261decf57e3584 469 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 12 149 7.1E-71 T 13-09-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 THL1_RS01605 ea17ab649bee8414fd261decf57e3584 469 SMART SM00996 12 468 1.9E-276 T 13-09-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 THL1_RS01605 ea17ab649bee8414fd261decf57e3584 469 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 13 461 7.6E-153 T 13-09-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 THL1_RS01605 ea17ab649bee8414fd261decf57e3584 469 Gene3D G3DSA:3.40.50.720 201 380 3.0E-43 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS01605 ea17ab649bee8414fd261decf57e3584 469 PIRSF PIRSF001109 1 469 1.4E-184 T 13-09-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 THL1_RS01605 ea17ab649bee8414fd261decf57e3584 469 PANTHER PTHR23420 4 469 0.0 T 13-09-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 THL1_RS01605 ea17ab649bee8414fd261decf57e3584 469 Gene3D G3DSA:3.40.50.1480 382 469 8.8E-131 T 13-09-2016 THL1_RS01605 ea17ab649bee8414fd261decf57e3584 469 Gene3D G3DSA:3.40.50.1480 12 200 8.8E-131 T 13-09-2016 THL1_RS01605 ea17ab649bee8414fd261decf57e3584 469 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 221 237 - T 13-09-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 THL1_RS01605 ea17ab649bee8414fd261decf57e3584 469 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 8 461 43.808 T 13-09-2016 IPR000043 Adenosylhomocysteinase GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 THL1_RS01605 ea17ab649bee8414fd261decf57e3584 469 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 84 98 - T 13-09-2016 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 THL1_RS01605 ea17ab649bee8414fd261decf57e3584 469 SMART SM00997 199 381 1.7E-82 T 13-09-2016 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|UniPathway: UPA00314 THL1_RS01605 ea17ab649bee8414fd261decf57e3584 469 SUPERFAMILY SSF51735 199 381 1.14E-50 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 629 642 6.3E-65 T 13-09-2016 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 352 369 6.3E-65 T 13-09-2016 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 6.3E-65 T 13-09-2016 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 190 205 6.3E-65 T 13-09-2016 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 6.3E-65 T 13-09-2016 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 314 329 6.3E-65 T 13-09-2016 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 395 414 6.3E-65 T 13-09-2016 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PANTHER PTHR30009 1 418 0.0 T 13-09-2016 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PANTHER PTHR30009 471 652 0.0 T 13-09-2016 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 Pfam PF01578 Cytochrome C assembly protein 89 296 6.1E-55 T 13-09-2016 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 639 3.6E-236 T 13-09-2016 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 1.3E-96 T 13-09-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 1.3E-96 T 13-09-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 211 237 1.3E-96 T 13-09-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 275 295 1.3E-96 T 13-09-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 160 182 1.3E-96 T 13-09-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 245 265 1.3E-96 T 13-09-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 311 330 1.3E-96 T 13-09-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 295 311 1.3E-96 T 13-09-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PANTHER PTHR30009:SF0 471 652 0.0 T 13-09-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 PANTHER PTHR30009:SF0 1 418 0.0 T 13-09-2016 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19415 75ee82488181eae3f626823020c88db5 657 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 316 636 2.3E-122 T 13-09-2016 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal THL1_RS26640 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF03050 Transposase IS66 family 110 395 1.4E-102 T 13-09-2016 IPR004291 Transposase, IS66 THL1_RS26640 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13005 zinc-finger binding domain of transposase IS66 54 95 2.5E-13 T 13-09-2016 IPR024474 Zinc-finger binding domain of transposase IS66 THL1_RS26640 1c9615f54755bafe4b6225e1ea4a60cb 448 PANTHER PTHR33678 24 439 2.4E-91 T 13-09-2016 THL1_RS26640 1c9615f54755bafe4b6225e1ea4a60cb 448 PANTHER PTHR33678:SF1 24 439 2.4E-91 T 13-09-2016 THL1_RS26640 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13817 IS66 C-terminal element 402 440 7.5E-19 T 13-09-2016 THL1_RS26640 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13007 Transposase C of IS166 homeodomain 9 44 2.6E-5 T 13-09-2016 IPR024463 Transposase TnpC, homeodomain THL1_RS09885 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF03050 Transposase IS66 family 110 395 1.4E-102 T 13-09-2016 IPR004291 Transposase, IS66 THL1_RS09885 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13005 zinc-finger binding domain of transposase IS66 54 95 2.5E-13 T 13-09-2016 IPR024474 Zinc-finger binding domain of transposase IS66 THL1_RS09885 1c9615f54755bafe4b6225e1ea4a60cb 448 PANTHER PTHR33678 24 439 2.4E-91 T 13-09-2016 THL1_RS09885 1c9615f54755bafe4b6225e1ea4a60cb 448 PANTHER PTHR33678:SF1 24 439 2.4E-91 T 13-09-2016 THL1_RS09885 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13817 IS66 C-terminal element 402 440 7.5E-19 T 13-09-2016 THL1_RS09885 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13007 Transposase C of IS166 homeodomain 9 44 2.6E-5 T 13-09-2016 IPR024463 Transposase TnpC, homeodomain THL1_RS08880 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF03050 Transposase IS66 family 110 395 1.4E-102 T 13-09-2016 IPR004291 Transposase, IS66 THL1_RS08880 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13005 zinc-finger binding domain of transposase IS66 54 95 2.5E-13 T 13-09-2016 IPR024474 Zinc-finger binding domain of transposase IS66 THL1_RS08880 1c9615f54755bafe4b6225e1ea4a60cb 448 PANTHER PTHR33678 24 439 2.4E-91 T 13-09-2016 THL1_RS08880 1c9615f54755bafe4b6225e1ea4a60cb 448 PANTHER PTHR33678:SF1 24 439 2.4E-91 T 13-09-2016 THL1_RS08880 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13817 IS66 C-terminal element 402 440 7.5E-19 T 13-09-2016 THL1_RS08880 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13007 Transposase C of IS166 homeodomain 9 44 2.6E-5 T 13-09-2016 IPR024463 Transposase TnpC, homeodomain THL1_RS05445 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF03050 Transposase IS66 family 110 395 1.4E-102 T 13-09-2016 IPR004291 Transposase, IS66 THL1_RS05445 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13005 zinc-finger binding domain of transposase IS66 54 95 2.5E-13 T 13-09-2016 IPR024474 Zinc-finger binding domain of transposase IS66 THL1_RS05445 1c9615f54755bafe4b6225e1ea4a60cb 448 PANTHER PTHR33678 24 439 2.4E-91 T 13-09-2016 THL1_RS05445 1c9615f54755bafe4b6225e1ea4a60cb 448 PANTHER PTHR33678:SF1 24 439 2.4E-91 T 13-09-2016 THL1_RS05445 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13817 IS66 C-terminal element 402 440 7.5E-19 T 13-09-2016 THL1_RS05445 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13007 Transposase C of IS166 homeodomain 9 44 2.6E-5 T 13-09-2016 IPR024463 Transposase TnpC, homeodomain THL1_RS16240 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF03050 Transposase IS66 family 110 395 1.4E-102 T 13-09-2016 IPR004291 Transposase, IS66 THL1_RS16240 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13005 zinc-finger binding domain of transposase IS66 54 95 2.5E-13 T 13-09-2016 IPR024474 Zinc-finger binding domain of transposase IS66 THL1_RS16240 1c9615f54755bafe4b6225e1ea4a60cb 448 PANTHER PTHR33678 24 439 2.4E-91 T 13-09-2016 THL1_RS16240 1c9615f54755bafe4b6225e1ea4a60cb 448 PANTHER PTHR33678:SF1 24 439 2.4E-91 T 13-09-2016 THL1_RS16240 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13817 IS66 C-terminal element 402 440 7.5E-19 T 13-09-2016 THL1_RS16240 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13007 Transposase C of IS166 homeodomain 9 44 2.6E-5 T 13-09-2016 IPR024463 Transposase TnpC, homeodomain THL1_RS26940 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF03050 Transposase IS66 family 110 395 1.4E-102 T 13-09-2016 IPR004291 Transposase, IS66 THL1_RS26940 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13005 zinc-finger binding domain of transposase IS66 54 95 2.5E-13 T 13-09-2016 IPR024474 Zinc-finger binding domain of transposase IS66 THL1_RS26940 1c9615f54755bafe4b6225e1ea4a60cb 448 PANTHER PTHR33678 24 439 2.4E-91 T 13-09-2016 THL1_RS26940 1c9615f54755bafe4b6225e1ea4a60cb 448 PANTHER PTHR33678:SF1 24 439 2.4E-91 T 13-09-2016 THL1_RS26940 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13817 IS66 C-terminal element 402 440 7.5E-19 T 13-09-2016 THL1_RS26940 1c9615f54755bafe4b6225e1ea4a60cb 448 Pfam PF13007 Transposase C of IS166 homeodomain 9 44 2.6E-5 T 13-09-2016 IPR024463 Transposase TnpC, homeodomain THL1_RS13285 6141780d9fdf26c8ec01327113d3424c 123 Pfam PF00011 Hsp20/alpha crystallin family 22 120 6.5E-18 T 13-09-2016 IPR002068 Alpha crystallin/Hsp20 domain THL1_RS13285 6141780d9fdf26c8ec01327113d3424c 123 PANTHER PTHR11527 18 123 1.7E-21 T 13-09-2016 IPR031107 Small heat shock protein HSP20 THL1_RS13285 6141780d9fdf26c8ec01327113d3424c 123 SUPERFAMILY SSF49764 14 120 4.88E-26 T 13-09-2016 IPR008978 HSP20-like chaperone THL1_RS13285 6141780d9fdf26c8ec01327113d3424c 123 Gene3D G3DSA:2.60.40.790 14 121 3.5E-24 T 13-09-2016 IPR008978 HSP20-like chaperone THL1_RS13285 6141780d9fdf26c8ec01327113d3424c 123 PANTHER PTHR11527:SF118 18 123 1.7E-21 T 13-09-2016 THL1_RS09635 76144193ede21e3ec2b0ccdfafa80d2b 242 Gene3D G3DSA:3.40.190.10 127 192 3.6E-4 T 13-09-2016 THL1_RS09635 76144193ede21e3ec2b0ccdfafa80d2b 242 SMART SM00062 22 242 0.0022 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS09635 76144193ede21e3ec2b0ccdfafa80d2b 242 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 241 5.2E-19 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS09635 76144193ede21e3ec2b0ccdfafa80d2b 242 SUPERFAMILY SSF53850 18 241 8.78E-31 T 13-09-2016 THL1_RS09635 76144193ede21e3ec2b0ccdfafa80d2b 242 Gene3D G3DSA:3.40.190.10 34 126 2.4E-9 T 13-09-2016 THL1_RS09635 76144193ede21e3ec2b0ccdfafa80d2b 242 PANTHER PTHR35936 1 242 4.8E-15 T 13-09-2016 THL1_RS03465 fd5b15463d70d82bd998d0e97db94f80 177 Gene3D G3DSA:2.30.30.30 116 177 8.6E-31 T 13-09-2016 IPR014722 Ribosomal protein L2 domain 2 THL1_RS03465 fd5b15463d70d82bd998d0e97db94f80 177 SMART SM00739 123 150 2.9E-7 T 13-09-2016 IPR005824 KOW THL1_RS03465 fd5b15463d70d82bd998d0e97db94f80 177 SUPERFAMILY SSF82679 3 113 4.05E-39 T 13-09-2016 IPR006645 NusG, N-terminal GO:0006355 THL1_RS03465 fd5b15463d70d82bd998d0e97db94f80 177 Pfam PF02357 Transcription termination factor nusG 3 108 3.4E-28 T 13-09-2016 IPR006645 NusG, N-terminal GO:0006355 THL1_RS03465 fd5b15463d70d82bd998d0e97db94f80 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 8.4E-20 T 13-09-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 THL1_RS03465 fd5b15463d70d82bd998d0e97db94f80 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 8.4E-20 T 13-09-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 THL1_RS03465 fd5b15463d70d82bd998d0e97db94f80 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 8.4E-20 T 13-09-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 THL1_RS03465 fd5b15463d70d82bd998d0e97db94f80 177 SMART SM00738 2 111 4.6E-49 T 13-09-2016 IPR006645 NusG, N-terminal GO:0006355 THL1_RS03465 fd5b15463d70d82bd998d0e97db94f80 177 Gene3D G3DSA:3.30.70.940 3 112 2.9E-44 T 13-09-2016 IPR006645 NusG, N-terminal GO:0006355 THL1_RS03465 fd5b15463d70d82bd998d0e97db94f80 177 Pfam PF00467 KOW motif 126 156 3.8E-9 T 13-09-2016 IPR005824 KOW THL1_RS03465 fd5b15463d70d82bd998d0e97db94f80 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 1.0E-67 T 13-09-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 THL1_RS03465 fd5b15463d70d82bd998d0e97db94f80 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 13-09-2016 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site THL1_RS03465 fd5b15463d70d82bd998d0e97db94f80 177 PANTHER PTHR30265 1 176 5.5E-83 T 13-09-2016 THL1_RS03465 fd5b15463d70d82bd998d0e97db94f80 177 SUPERFAMILY SSF50104 121 176 3.74E-19 T 13-09-2016 IPR008991 Translation protein SH3-like domain THL1_RS03465 fd5b15463d70d82bd998d0e97db94f80 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 24.903 T 13-09-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 THL1_RS03690 014a726ee89e1cb323a955915df7e38c 166 PANTHER PTHR30173:SF9 8 159 8.2E-41 T 13-09-2016 THL1_RS03690 014a726ee89e1cb323a955915df7e38c 166 Pfam PF08281 Sigma-70, region 4 107 159 8.0E-15 T 13-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS03690 014a726ee89e1cb323a955915df7e38c 166 SUPERFAMILY SSF88659 85 159 1.0E-14 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS03690 014a726ee89e1cb323a955915df7e38c 166 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 156 9.6E-23 T 13-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS03690 014a726ee89e1cb323a955915df7e38c 166 Gene3D G3DSA:1.10.10.10 104 156 9.2E-13 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS03690 014a726ee89e1cb323a955915df7e38c 166 Gene3D G3DSA:1.10.1740.10 8 76 5.4E-14 T 13-09-2016 THL1_RS03690 014a726ee89e1cb323a955915df7e38c 166 SUPERFAMILY SSF88946 8 96 2.75E-16 T 13-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS03690 014a726ee89e1cb323a955915df7e38c 166 Pfam PF04542 Sigma-70 region 2 11 75 1.8E-14 T 13-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS03690 014a726ee89e1cb323a955915df7e38c 166 PANTHER PTHR30173 8 159 8.2E-41 T 13-09-2016 THL1_RS19315 17b26053550e6d4c08d513769b6f2198 105 PANTHER PTHR34205:SF1 9 104 6.1E-50 T 13-09-2016 THL1_RS19315 17b26053550e6d4c08d513769b6f2198 105 PANTHER PTHR34205 9 104 6.1E-50 T 13-09-2016 THL1_RS19315 17b26053550e6d4c08d513769b6f2198 105 Pfam PF06127 Protein of unknown function (DUF962) 9 102 1.9E-37 T 13-09-2016 IPR009305 Protein of unknown function DUF962 THL1_RS07005 6e8db04d561592766dc799620f8b00bb 469 PIRSF PIRSF006060 1 463 2.2E-69 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS07005 6e8db04d561592766dc799620f8b00bb 469 Pfam PF00324 Amino acid permease 18 455 6.4E-116 T 13-09-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 THL1_RS07005 6e8db04d561592766dc799620f8b00bb 469 ProSitePatterns PS00218 Amino acid permeases signature. 43 73 - T 13-09-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 THL1_RS07005 6e8db04d561592766dc799620f8b00bb 469 PANTHER PTHR11785:SF26 1 464 3.1E-304 T 13-09-2016 THL1_RS07005 6e8db04d561592766dc799620f8b00bb 469 PANTHER PTHR11785 1 464 3.1E-304 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS27930 87e2b4ab2ae6058024d79ddf98e401ee 242 PANTHER PTHR33446:SF2 37 241 6.7E-19 T 13-09-2016 THL1_RS27930 87e2b4ab2ae6058024d79ddf98e401ee 242 PANTHER PTHR33446 37 241 6.7E-19 T 13-09-2016 THL1_RS27930 87e2b4ab2ae6058024d79ddf98e401ee 242 Gene3D G3DSA:3.30.1150.10 125 240 4.3E-20 T 13-09-2016 THL1_RS27930 87e2b4ab2ae6058024d79ddf98e401ee 242 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 160 239 2.3E-16 T 13-09-2016 IPR006260 TonB, C-terminal GO:0006810 THL1_RS27930 87e2b4ab2ae6058024d79ddf98e401ee 242 PRINTS PR01374 Gram-negative bacterial tonB protein signature 155 176 4.1E-5 T 13-09-2016 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 THL1_RS27930 87e2b4ab2ae6058024d79ddf98e401ee 242 PRINTS PR01374 Gram-negative bacterial tonB protein signature 87 97 4.1E-5 T 13-09-2016 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 THL1_RS27930 87e2b4ab2ae6058024d79ddf98e401ee 242 PRINTS PR01374 Gram-negative bacterial tonB protein signature 176 194 4.1E-5 T 13-09-2016 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 THL1_RS27930 87e2b4ab2ae6058024d79ddf98e401ee 242 SUPERFAMILY SSF74653 144 237 1.7E-16 T 13-09-2016 THL1_RS27930 87e2b4ab2ae6058024d79ddf98e401ee 242 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 161 239 1.0E-18 T 13-09-2016 IPR006260 TonB, C-terminal GO:0006810 THL1_RS21615 698389379f5baa3cd94a3685f32de130 507 SUPERFAMILY SSF103190 83 198 1.57E-5 T 13-09-2016 IPR029151 Periplasmic sensor domain-like THL1_RS21615 698389379f5baa3cd94a3685f32de130 507 Pfam PF02743 Cache domain 50 270 1.3E-20 T 13-09-2016 IPR033479 Double Cache domain 1 THL1_RS21615 698389379f5baa3cd94a3685f32de130 507 SUPERFAMILY SSF55073 344 504 2.82E-48 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS21615 698389379f5baa3cd94a3685f32de130 507 PANTHER PTHR10799:SF750 184 323 5.8E-31 T 13-09-2016 THL1_RS21615 698389379f5baa3cd94a3685f32de130 507 SMART SM00267 328 503 1.3E-63 T 13-09-2016 IPR000160 GGDEF domain THL1_RS21615 698389379f5baa3cd94a3685f32de130 507 Gene3D G3DSA:3.30.450.20 91 190 1.1E-17 T 13-09-2016 THL1_RS21615 698389379f5baa3cd94a3685f32de130 507 PANTHER PTHR10799 184 323 5.8E-31 T 13-09-2016 THL1_RS21615 698389379f5baa3cd94a3685f32de130 507 PANTHER PTHR10799:SF750 372 500 5.8E-31 T 13-09-2016 THL1_RS21615 698389379f5baa3cd94a3685f32de130 507 PANTHER PTHR10799 372 500 5.8E-31 T 13-09-2016 THL1_RS21615 698389379f5baa3cd94a3685f32de130 507 Pfam PF00990 Diguanylate cyclase, GGDEF domain 339 499 4.9E-47 T 13-09-2016 IPR000160 GGDEF domain THL1_RS21615 698389379f5baa3cd94a3685f32de130 507 Gene3D G3DSA:3.30.70.270 341 505 1.8E-53 T 13-09-2016 THL1_RS21615 698389379f5baa3cd94a3685f32de130 507 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 337 502 4.2E-52 T 13-09-2016 IPR000160 GGDEF domain THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 PANTHER PTHR10724:SF6 1 514 2.8E-269 T 13-09-2016 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 SMART SM00316 362 434 1.6E-20 T 13-09-2016 IPR022967 RNA-binding domain, S1 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 SMART SM00316 275 347 8.4E-27 T 13-09-2016 IPR022967 RNA-binding domain, S1 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 SMART SM00316 190 260 1.4E-28 T 13-09-2016 IPR022967 RNA-binding domain, S1 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 SMART SM00316 449 520 5.7E-22 T 13-09-2016 IPR022967 RNA-binding domain, S1 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 SMART SM00316 103 171 2.4E-8 T 13-09-2016 IPR022967 RNA-binding domain, S1 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 SMART SM00316 19 87 2.0E-5 T 13-09-2016 IPR022967 RNA-binding domain, S1 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 Gene3D G3DSA:2.40.50.140 192 279 4.6E-31 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 Gene3D G3DSA:2.40.50.140 280 363 9.7E-29 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 Gene3D G3DSA:2.40.50.140 21 101 3.9E-11 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 SUPERFAMILY SSF50249 255 354 4.29E-26 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 SUPERFAMILY SSF50249 1 112 1.64E-20 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 3 520 4.9E-220 T 13-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 Gene3D G3DSA:2.40.50.140 364 442 9.0E-25 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 SUPERFAMILY SSF50249 342 440 1.19E-22 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 PRINTS PR00681 Ribosomal protein S1 signature 212 233 9.5E-89 T 13-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 PRINTS PR00681 Ribosomal protein S1 signature 290 309 9.5E-89 T 13-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 PRINTS PR00681 Ribosomal protein S1 signature 21 39 9.5E-89 T 13-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 PRINTS PR00681 Ribosomal protein S1 signature 39 53 9.5E-89 T 13-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 PRINTS PR00681 Ribosomal protein S1 signature 84 103 9.5E-89 T 13-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 PRINTS PR00681 Ribosomal protein S1 signature 126 143 9.5E-89 T 13-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 PRINTS PR00681 Ribosomal protein S1 signature 108 124 9.5E-89 T 13-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 PRINTS PR00681 Ribosomal protein S1 signature 155 175 9.5E-89 T 13-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 PRINTS PR00681 Ribosomal protein S1 signature 330 348 9.5E-89 T 13-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 Pfam PF00575 S1 RNA binding domain 19 85 3.6E-7 T 13-09-2016 IPR003029 S1 domain GO:0003676 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 Pfam PF00575 S1 RNA binding domain 361 434 2.8E-18 T 13-09-2016 IPR003029 S1 domain GO:0003676 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 Pfam PF00575 S1 RNA binding domain 448 520 3.3E-16 T 13-09-2016 IPR003029 S1 domain GO:0003676 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 Pfam PF00575 S1 RNA binding domain 189 260 8.9E-22 T 13-09-2016 IPR003029 S1 domain GO:0003676 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 Pfam PF00575 S1 RNA binding domain 275 347 1.5E-21 T 13-09-2016 IPR003029 S1 domain GO:0003676 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 Pfam PF00575 S1 RNA binding domain 103 171 2.4E-11 T 13-09-2016 IPR003029 S1 domain GO:0003676 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 PANTHER PTHR10724 1 514 2.8E-269 T 13-09-2016 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 SUPERFAMILY SSF50249 429 538 4.25E-24 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 PIRSF PIRSF002111 1 534 9.2E-215 T 13-09-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 SUPERFAMILY SSF50249 105 185 3.0E-14 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 Gene3D G3DSA:2.40.50.140 102 172 1.9E-14 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 Gene3D G3DSA:2.40.50.140 444 520 4.3E-23 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS09790 79871ee90b75536c69abb09e5b25e01e 559 SUPERFAMILY SSF50249 189 277 1.94E-27 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS07970 d0a175cab5789d76c26de567dbb77f4b 242 PANTHER PTHR10108:SF809 5 215 1.1E-52 T 13-09-2016 THL1_RS07970 d0a175cab5789d76c26de567dbb77f4b 242 SUPERFAMILY SSF53335 5 236 4.45E-41 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS07970 d0a175cab5789d76c26de567dbb77f4b 242 Gene3D G3DSA:3.40.50.150 15 211 2.0E-30 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS07970 d0a175cab5789d76c26de567dbb77f4b 242 PANTHER PTHR10108 5 215 1.1E-52 T 13-09-2016 THL1_RS07970 d0a175cab5789d76c26de567dbb77f4b 242 Pfam PF08241 Methyltransferase domain 48 141 2.7E-19 T 13-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 THL1_RS19190 03805dc697c5f47c8a65ed163a0adad6 364 Gene3D G3DSA:3.40.190.10 93 180 7.8E-32 T 13-09-2016 THL1_RS19190 03805dc697c5f47c8a65ed163a0adad6 364 TIGRFAM TIGR01807 CM_P2: chorismate mutase 6 84 1.8E-31 T 13-09-2016 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626|UniPathway: UPA00120|UniPathway: UPA00121 THL1_RS19190 03805dc697c5f47c8a65ed163a0adad6 364 SUPERFAMILY SSF55021 266 361 2.5E-28 T 13-09-2016 THL1_RS19190 03805dc697c5f47c8a65ed163a0adad6 364 Gene3D G3DSA:3.40.190.10 181 259 1.7E-29 T 13-09-2016 THL1_RS19190 03805dc697c5f47c8a65ed163a0adad6 364 PANTHER PTHR21022 3 360 1.1E-140 T 13-09-2016 THL1_RS19190 03805dc697c5f47c8a65ed163a0adad6 364 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 309 316 - T 13-09-2016 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 THL1_RS19190 03805dc697c5f47c8a65ed163a0adad6 364 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 247 269 - T 13-09-2016 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 THL1_RS19190 03805dc697c5f47c8a65ed163a0adad6 364 PIRSF PIRSF001500 1 364 1.2E-148 T 13-09-2016 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 THL1_RS19190 03805dc697c5f47c8a65ed163a0adad6 364 SMART SM00830 10 94 3.4E-26 T 13-09-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 THL1_RS19190 03805dc697c5f47c8a65ed163a0adad6 364 Gene3D G3DSA:1.20.59.10 2 92 4.5E-21 T 13-09-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 THL1_RS19190 03805dc697c5f47c8a65ed163a0adad6 364 Pfam PF00800 Prephenate dehydratase 96 273 1.9E-62 T 13-09-2016 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 THL1_RS19190 03805dc697c5f47c8a65ed163a0adad6 364 SUPERFAMILY SSF53850 95 280 8.68E-61 T 13-09-2016 THL1_RS19190 03805dc697c5f47c8a65ed163a0adad6 364 Pfam PF01817 Chorismate mutase type II 10 92 3.5E-22 T 13-09-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 THL1_RS19190 03805dc697c5f47c8a65ed163a0adad6 364 PANTHER PTHR21022:SF0 3 360 1.1E-140 T 13-09-2016 THL1_RS19190 03805dc697c5f47c8a65ed163a0adad6 364 Gene3D G3DSA:3.30.70.260 275 362 3.9E-31 T 13-09-2016 THL1_RS19190 03805dc697c5f47c8a65ed163a0adad6 364 Pfam PF01842 ACT domain 282 346 2.9E-11 T 13-09-2016 IPR002912 ACT domain GO:0008152|GO:0016597 THL1_RS19190 03805dc697c5f47c8a65ed163a0adad6 364 SUPERFAMILY SSF48600 5 98 4.73E-19 T 13-09-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 THL1_RS15740 50a40e8b0bd573eff54c57fafe2d4620 330 Gene3D G3DSA:1.20.1260.10 36 292 2.5E-98 T 13-09-2016 IPR012347 Ferritin-related THL1_RS15740 50a40e8b0bd573eff54c57fafe2d4620 330 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 26 315 1.8E-166 T 13-09-2016 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.149+1.14.13.14|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176|UniPathway: UPA00930 THL1_RS15740 50a40e8b0bd573eff54c57fafe2d4620 330 PANTHER PTHR30458:SF0 5 325 5.5E-153 T 13-09-2016 THL1_RS15740 50a40e8b0bd573eff54c57fafe2d4620 330 Pfam PF05138 Phenylacetic acid catabolic protein 36 311 4.3E-97 T 13-09-2016 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 UniPathway: UPA00930 THL1_RS15740 50a40e8b0bd573eff54c57fafe2d4620 330 SUPERFAMILY SSF47240 46 290 6.14E-80 T 13-09-2016 IPR009078 Ferritin-like superfamily THL1_RS15740 50a40e8b0bd573eff54c57fafe2d4620 330 PANTHER PTHR30458 5 325 5.5E-153 T 13-09-2016 THL1_RS12770 0aa025be6eed16a9a50c7cff38be5704 647 PANTHER PTHR37031:SF2 122 238 2.1E-109 T 13-09-2016 THL1_RS12770 0aa025be6eed16a9a50c7cff38be5704 647 PANTHER PTHR37031 122 238 2.1E-109 T 13-09-2016 THL1_RS12770 0aa025be6eed16a9a50c7cff38be5704 647 PANTHER PTHR37031 301 637 2.1E-109 T 13-09-2016 THL1_RS12770 0aa025be6eed16a9a50c7cff38be5704 647 PANTHER PTHR37031:SF2 301 637 2.1E-109 T 13-09-2016 THL1_RS12770 0aa025be6eed16a9a50c7cff38be5704 647 SUPERFAMILY SSF56300 399 549 1.64E-8 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS12770 0aa025be6eed16a9a50c7cff38be5704 647 SUPERFAMILY SSF56300 305 347 1.64E-8 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS12770 0aa025be6eed16a9a50c7cff38be5704 647 SUPERFAMILY SSF56300 143 187 1.64E-8 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS21285 4c2c3f7c462eb623d780b320550051dd 232 Pfam PF02565 Recombination protein O C terminal 80 221 7.7E-25 T 13-09-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 THL1_RS21285 4c2c3f7c462eb623d780b320550051dd 232 PANTHER PTHR33991 2 232 5.9E-45 T 13-09-2016 THL1_RS21285 4c2c3f7c462eb623d780b320550051dd 232 Hamap MF_00201 DNA repair protein RecO [recO]. 2 226 19.491 T 13-09-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 THL1_RS21285 4c2c3f7c462eb623d780b320550051dd 232 Pfam PF11967 Recombination protein O N terminal 6 70 4.2E-14 T 13-09-2016 IPR022572 DNA replication/recombination mediator RecO, N-terminal THL1_RS21285 4c2c3f7c462eb623d780b320550051dd 232 TIGRFAM TIGR00613 reco: DNA repair protein RecO 8 144 5.3E-18 T 13-09-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 THL1_RS21285 4c2c3f7c462eb623d780b320550051dd 232 SUPERFAMILY SSF57863 83 141 2.33E-9 T 13-09-2016 THL1_RS21285 4c2c3f7c462eb623d780b320550051dd 232 SUPERFAMILY SSF50249 5 71 1.05E-10 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS21285 4c2c3f7c462eb623d780b320550051dd 232 Gene3D G3DSA:2.40.50.140 8 64 1.3E-4 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS02620 da255168f620606297e42c2f9ddbe0f7 920 PANTHER PTHR30189 146 511 9.5E-99 T 13-09-2016 THL1_RS02620 da255168f620606297e42c2f9ddbe0f7 920 PANTHER PTHR30189 531 889 9.5E-99 T 13-09-2016 THL1_RS02620 da255168f620606297e42c2f9ddbe0f7 920 Pfam PF03968 OstA-like protein 150 283 4.0E-13 T 13-09-2016 IPR005653 Organic solvent tolerance-like, N-terminal THL1_RS02620 da255168f620606297e42c2f9ddbe0f7 920 Gene3D G3DSA:2.60.450.10 145 296 5.9E-20 T 13-09-2016 THL1_RS02620 da255168f620606297e42c2f9ddbe0f7 920 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 17 895 20.984 T 13-09-2016 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 THL1_RS02620 da255168f620606297e42c2f9ddbe0f7 920 Pfam PF04453 Organic solvent tolerance protein 396 825 7.6E-113 T 13-09-2016 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 THL1_RS22580 aa1b0687bab15c355c3107f3f1a484a1 258 PIRSF PIRSF000456 1 258 6.1E-99 T 13-09-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 THL1_RS22580 aa1b0687bab15c355c3107f3f1a484a1 258 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 176 256 2.8E-27 T 13-09-2016 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 THL1_RS22580 aa1b0687bab15c355c3107f3f1a484a1 258 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 4 32 - T 13-09-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 THL1_RS22580 aa1b0687bab15c355c3107f3f1a484a1 258 SUPERFAMILY SSF51161 3 258 3.58E-78 T 13-09-2016 IPR011004 Trimeric LpxA-like THL1_RS22580 aa1b0687bab15c355c3107f3f1a484a1 258 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 14 48 9.4E-9 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS22580 aa1b0687bab15c355c3107f3f1a484a1 258 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 105 137 3.1E-6 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS22580 aa1b0687bab15c355c3107f3f1a484a1 258 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 4 256 8.9E-95 T 13-09-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 THL1_RS22580 aa1b0687bab15c355c3107f3f1a484a1 258 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 1 258 44.513 T 13-09-2016 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 THL1_RS22580 aa1b0687bab15c355c3107f3f1a484a1 258 Gene3D G3DSA:2.160.10.10 3 189 1.0E-49 T 13-09-2016 THL1_RS22580 aa1b0687bab15c355c3107f3f1a484a1 258 PANTHER PTHR23416 1 250 6.5E-127 T 13-09-2016 THL1_RS22580 aa1b0687bab15c355c3107f3f1a484a1 258 Gene3D G3DSA:1.20.1180.10 193 258 1.6E-25 T 13-09-2016 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12|UniPathway: UPA00359 THL1_RS22580 aa1b0687bab15c355c3107f3f1a484a1 258 PANTHER PTHR23416:SF8 1 250 6.5E-127 T 13-09-2016 THL1_RS12195 8154289c8fa5a9731798ad0ff40740a5 367 SUPERFAMILY SSF55729 1 148 1.17E-24 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS12195 8154289c8fa5a9731798ad0ff40740a5 367 Pfam PF11814 Peptidase_C39 like family 160 362 2.0E-76 T 13-09-2016 IPR021770 Protein of unknown function DUF3335 THL1_RS12195 8154289c8fa5a9731798ad0ff40740a5 367 PANTHER PTHR23091:SF256 1 181 2.3E-44 T 13-09-2016 THL1_RS12195 8154289c8fa5a9731798ad0ff40740a5 367 PANTHER PTHR23091 1 181 2.3E-44 T 13-09-2016 THL1_RS12195 8154289c8fa5a9731798ad0ff40740a5 367 Gene3D G3DSA:3.40.630.30 2 148 1.1E-25 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS12195 8154289c8fa5a9731798ad0ff40740a5 367 Pfam PF00583 Acetyltransferase (GNAT) family 53 126 1.6E-12 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 SUPERFAMILY SSF55785 285 412 3.14E-26 T 13-09-2016 IPR000014 PAS domain THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 PANTHER PTHR24423:SF477 38 559 2.8E-61 T 13-09-2016 THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 Pfam PF00989 PAS fold 554 669 1.4E-10 T 13-09-2016 IPR013767 PAS fold GO:0006355 THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 Pfam PF05231 MASE1 15 243 1.5E-14 T 13-09-2016 IPR007895 MASE1 THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 SUPERFAMILY SSF55785 434 544 2.62E-19 T 13-09-2016 IPR000014 PAS domain THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 SMART SM00086 500 542 3.7E-5 T 13-09-2016 IPR001610 PAC motif THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 SMART SM00086 373 415 1.9E-7 T 13-09-2016 IPR001610 PAC motif THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 SMART SM00086 630 672 0.74 T 13-09-2016 IPR001610 PAC motif THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 Gene3D G3DSA:3.30.450.20 540 670 5.2E-20 T 13-09-2016 THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 Gene3D G3DSA:3.30.450.20 287 413 1.4E-28 T 13-09-2016 THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 PANTHER PTHR24423:SF477 816 826 2.8E-61 T 13-09-2016 THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 Pfam PF08447 PAS fold 325 407 7.0E-11 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 Pfam PF08447 PAS fold 450 536 2.1E-17 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 Pfam PF00990 Diguanylate cyclase, GGDEF domain 683 839 9.5E-44 T 13-09-2016 IPR000160 GGDEF domain THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 SMART SM00091 554 622 1.4E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 SMART SM00091 300 366 4.3E-10 T 13-09-2016 IPR000014 PAS domain THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 SMART SM00091 427 494 0.81 T 13-09-2016 IPR000014 PAS domain THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 Gene3D G3DSA:3.30.70.270 684 843 1.0E-52 T 13-09-2016 THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 PANTHER PTHR24423 816 826 2.8E-61 T 13-09-2016 THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 Gene3D G3DSA:3.30.450.20 419 539 7.5E-22 T 13-09-2016 THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 SUPERFAMILY SSF55073 688 843 1.02E-44 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 427 549 9.1E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 297 421 5.1E-30 T 13-09-2016 IPR000014 PAS domain THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 551 678 5.6E-11 T 13-09-2016 IPR000014 PAS domain THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 SMART SM00267 672 844 2.8E-59 T 13-09-2016 IPR000160 GGDEF domain THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 681 843 1.0E-41 T 13-09-2016 IPR000160 GGDEF domain THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 PANTHER PTHR24423 38 559 2.8E-61 T 13-09-2016 THL1_RS25060 7da2facfab36ce4f5120bae8f6960c2c 846 SUPERFAMILY SSF55785 539 670 2.97E-20 T 13-09-2016 IPR000014 PAS domain THL1_RS05145 c410d563c866f88a129bc3d7b43fd273 261 PANTHER PTHR18966:SF152 37 253 7.2E-46 T 13-09-2016 THL1_RS05145 c410d563c866f88a129bc3d7b43fd273 261 Gene3D G3DSA:3.40.190.10 106 198 1.7E-16 T 13-09-2016 THL1_RS05145 c410d563c866f88a129bc3d7b43fd273 261 PANTHER PTHR18966 37 253 7.2E-46 T 13-09-2016 THL1_RS05145 c410d563c866f88a129bc3d7b43fd273 261 Gene3D G3DSA:3.40.190.10 35 105 3.8E-37 T 13-09-2016 THL1_RS05145 c410d563c866f88a129bc3d7b43fd273 261 Gene3D G3DSA:3.40.190.10 215 257 3.8E-37 T 13-09-2016 THL1_RS05145 c410d563c866f88a129bc3d7b43fd273 261 SMART SM00062 27 256 7.6E-49 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS05145 c410d563c866f88a129bc3d7b43fd273 261 SUPERFAMILY SSF53850 1 254 7.02E-54 T 13-09-2016 THL1_RS05145 c410d563c866f88a129bc3d7b43fd273 261 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 254 1.1E-54 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS16010 1cb0ff2dd22306901063834dd71268d8 259 PANTHER PTHR30413:SF2 1 259 1.7E-148 T 13-09-2016 THL1_RS16010 1cb0ff2dd22306901063834dd71268d8 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 179 198 2.8E-8 T 13-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THL1_RS16010 1cb0ff2dd22306901063834dd71268d8 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 61 83 2.8E-8 T 13-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THL1_RS16010 1cb0ff2dd22306901063834dd71268d8 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 199 218 2.8E-8 T 13-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THL1_RS16010 1cb0ff2dd22306901063834dd71268d8 259 PIRSF PIRSF006648 2 257 1.0E-23 T 13-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THL1_RS16010 1cb0ff2dd22306901063834dd71268d8 259 PANTHER PTHR30413 1 259 1.7E-148 T 13-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THL1_RS16010 1cb0ff2dd22306901063834dd71268d8 259 Pfam PF01061 ABC-2 type transporter 13 221 1.2E-37 T 13-09-2016 IPR013525 ABC-2 type transporter GO:0016020 THL1_RS22090 6dbbb0bce909252224c09f0f2797dc1f 165 Gene3D G3DSA:3.30.1330.60 56 164 2.2E-36 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS22090 6dbbb0bce909252224c09f0f2797dc1f 165 PANTHER PTHR30128:SF18 49 163 2.3E-50 T 13-09-2016 THL1_RS22090 6dbbb0bce909252224c09f0f2797dc1f 165 SUPERFAMILY SSF103088 58 164 7.72E-36 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS22090 6dbbb0bce909252224c09f0f2797dc1f 165 PRINTS PR01021 OMPA domain signature 95 110 1.2E-20 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS22090 6dbbb0bce909252224c09f0f2797dc1f 165 PRINTS PR01021 OMPA domain signature 110 126 1.2E-20 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS22090 6dbbb0bce909252224c09f0f2797dc1f 165 PRINTS PR01021 OMPA domain signature 66 88 1.2E-20 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS22090 6dbbb0bce909252224c09f0f2797dc1f 165 PANTHER PTHR30128 49 163 2.3E-50 T 13-09-2016 THL1_RS22090 6dbbb0bce909252224c09f0f2797dc1f 165 Pfam PF00691 OmpA family 65 159 1.8E-25 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS22090 6dbbb0bce909252224c09f0f2797dc1f 165 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 64 163 1.9E-41 T 13-09-2016 IPR014169 Peptidoglycan-associated lipoprotein GO:0009279 THL1_RS26220 6ca3bf54680d1ba00fbcf1e4db2965bc 600 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 285 452 1.1E-16 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS26220 6ca3bf54680d1ba00fbcf1e4db2965bc 600 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 271 1.9E-14 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS26220 6ca3bf54680d1ba00fbcf1e4db2965bc 600 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 42 156 4.9E-10 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS26220 6ca3bf54680d1ba00fbcf1e4db2965bc 600 PANTHER PTHR10909 1 374 2.7E-280 T 13-09-2016 THL1_RS26220 6ca3bf54680d1ba00fbcf1e4db2965bc 600 PANTHER PTHR10909 391 477 2.7E-280 T 13-09-2016 THL1_RS26220 6ca3bf54680d1ba00fbcf1e4db2965bc 600 Gene3D G3DSA:1.20.140.10 270 462 6.6E-45 T 13-09-2016 THL1_RS26220 6ca3bf54680d1ba00fbcf1e4db2965bc 600 PANTHER PTHR10909:SF269 1 374 2.7E-280 T 13-09-2016 THL1_RS26220 6ca3bf54680d1ba00fbcf1e4db2965bc 600 PANTHER PTHR10909:SF269 391 477 2.7E-280 T 13-09-2016 THL1_RS26220 6ca3bf54680d1ba00fbcf1e4db2965bc 600 Gene3D G3DSA:1.10.540.10 36 157 2.5E-16 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS26220 6ca3bf54680d1ba00fbcf1e4db2965bc 600 SUPERFAMILY SSF56645 36 271 7.98E-50 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS26220 6ca3bf54680d1ba00fbcf1e4db2965bc 600 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 8 34 3.3E-7 T 13-09-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria THL1_RS26220 6ca3bf54680d1ba00fbcf1e4db2965bc 600 SUPERFAMILY SSF47203 289 475 1.03E-40 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS26220 6ca3bf54680d1ba00fbcf1e4db2965bc 600 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 469 596 1.3E-35 T 13-09-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain THL1_RS26220 6ca3bf54680d1ba00fbcf1e4db2965bc 600 Gene3D G3DSA:2.40.110.10 160 269 8.8E-24 T 13-09-2016 THL1_RS21115 b5685db2744cffe59e5f18b8973a899f 194 Gene3D G3DSA:3.40.50.300 74 147 3.9E-13 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21115 b5685db2744cffe59e5f18b8973a899f 194 Gene3D G3DSA:3.40.50.300 2 15 3.9E-13 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21115 b5685db2744cffe59e5f18b8973a899f 194 Hamap MF_00836 Ribose 1,5-bisphosphate phosphokinase PhnN [phnN]. 2 183 34.058 T 13-09-2016 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-5532|UniPathway: UPA00087 THL1_RS21115 b5685db2744cffe59e5f18b8973a899f 194 TIGRFAM TIGR02322 phosphon_PhnN: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN 3 184 2.9E-65 T 13-09-2016 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-5532|UniPathway: UPA00087 THL1_RS21115 b5685db2744cffe59e5f18b8973a899f 194 PANTHER PTHR23117:SF8 1 186 6.2E-64 T 13-09-2016 THL1_RS21115 b5685db2744cffe59e5f18b8973a899f 194 SMART SM00072 2 186 3.9E-4 T 13-09-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit THL1_RS21115 b5685db2744cffe59e5f18b8973a899f 194 SUPERFAMILY SSF52540 3 187 4.27E-34 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21115 b5685db2744cffe59e5f18b8973a899f 194 PANTHER PTHR23117 1 186 6.2E-64 T 13-09-2016 THL1_RS21115 b5685db2744cffe59e5f18b8973a899f 194 Gene3D G3DSA:3.40.50.300 16 54 3.7E-4 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08505 43475695c346731f4ffdf462654e5170 260 SUPERFAMILY SSF51735 6 257 8.32E-66 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS08505 43475695c346731f4ffdf462654e5170 260 Gene3D G3DSA:3.40.50.720 1 257 2.1E-65 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS08505 43475695c346731f4ffdf462654e5170 260 PANTHER PTHR24319 1 260 1.2E-58 T 13-09-2016 THL1_RS08505 43475695c346731f4ffdf462654e5170 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 257 8.9E-42 T 13-09-2016 THL1_RS08505 43475695c346731f4ffdf462654e5170 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 6.2E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08505 43475695c346731f4ffdf462654e5170 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 6.2E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08505 43475695c346731f4ffdf462654e5170 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 6.2E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08505 43475695c346731f4ffdf462654e5170 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 6.2E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08505 43475695c346731f4ffdf462654e5170 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.2E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08505 43475695c346731f4ffdf462654e5170 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 6.2E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08505 43475695c346731f4ffdf462654e5170 260 PANTHER PTHR24319:SF23 1 260 1.2E-58 T 13-09-2016 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 79 347 1.2E-29 T 13-09-2016 IPR001757 P-type ATPase GO:0016021 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 369 604 9.8E-45 T 13-09-2016 IPR001757 P-type ATPase GO:0016021 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 SUPERFAMILY SSF81665 41 110 1.31E-9 T 13-09-2016 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 SUPERFAMILY SSF81665 212 303 1.31E-9 T 13-09-2016 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 541 553 3.4E-22 T 13-09-2016 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 465 475 3.4E-22 T 13-09-2016 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 518 537 3.4E-22 T 13-09-2016 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 158 172 3.4E-22 T 13-09-2016 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 309 323 3.4E-22 T 13-09-2016 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 Pfam PF00702 haloacid dehalogenase-like hydrolase 307 532 8.0E-34 T 13-09-2016 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 ProSitePatterns PS01229 Hypothetical cof family signature 2. 518 540 - T 13-09-2016 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 18 682 39.931 T 13-09-2016 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 311 317 - T 13-09-2016 IPR018303 P-type ATPase, phosphorylation site THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 SUPERFAMILY SSF56784 297 321 7.3E-39 T 13-09-2016 IPR023214 HAD-like domain THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 SUPERFAMILY SSF56784 379 406 7.3E-39 T 13-09-2016 IPR023214 HAD-like domain THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 SUPERFAMILY SSF56784 437 562 7.3E-39 T 13-09-2016 IPR023214 HAD-like domain THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 Gene3D G3DSA:3.40.1110.10 320 444 3.5E-40 T 13-09-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 17 678 6.9E-292 T 13-09-2016 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 SUPERFAMILY SSF81653 116 211 7.85E-21 T 13-09-2016 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 SUPERFAMILY SSF81660 320 453 2.16E-29 T 13-09-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 Pfam PF00122 E1-E2 ATPase 79 300 9.9E-38 T 13-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 Gene3D G3DSA:3.40.50.1000 445 565 2.7E-36 T 13-09-2016 IPR023214 HAD-like domain THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 Gene3D G3DSA:2.70.150.10 56 212 2.1E-22 T 13-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 PANTHER PTHR24093 627 679 0.0 T 13-09-2016 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 PANTHER PTHR24093:SF49 22 589 0.0 T 13-09-2016 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 PANTHER PTHR24093:SF49 627 679 0.0 T 13-09-2016 THL1_RS11225 7cfcdeda4ae27d5214637b153680f2d3 684 PANTHER PTHR24093 22 589 0.0 T 13-09-2016 THL1_RS02080 44284a8c10ebd911d6b2ff50486e372f 170 PANTHER PTHR38037 3 170 4.6E-46 T 13-09-2016 THL1_RS02080 44284a8c10ebd911d6b2ff50486e372f 170 Pfam PF05618 Putative ATP-dependant zinc protease 24 167 1.9E-44 T 13-09-2016 THL1_RS02080 44284a8c10ebd911d6b2ff50486e372f 170 Gene3D G3DSA:2.40.70.10 21 153 4.0E-43 T 13-09-2016 IPR021109 Aspartic peptidase domain THL1_RS02080 44284a8c10ebd911d6b2ff50486e372f 170 SUPERFAMILY SSF50630 23 165 1.63E-38 T 13-09-2016 IPR021109 Aspartic peptidase domain THL1_RS01815 5525b12ec4995b39ba92f7509d260a3a 519 PANTHER PTHR11780 1 510 4.3E-219 T 13-09-2016 THL1_RS01815 5525b12ec4995b39ba92f7509d260a3a 519 SUPERFAMILY SSF140490 422 510 5.1E-24 T 13-09-2016 THL1_RS01815 5525b12ec4995b39ba92f7509d260a3a 519 PANTHER PTHR11780:SF0 1 510 4.3E-219 T 13-09-2016 THL1_RS01815 5525b12ec4995b39ba92f7509d260a3a 519 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 263 278 - T 13-09-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 THL1_RS01815 5525b12ec4995b39ba92f7509d260a3a 519 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 438 449 - T 13-09-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 THL1_RS01815 5525b12ec4995b39ba92f7509d260a3a 519 SUPERFAMILY SSF142984 339 420 4.58E-21 T 13-09-2016 THL1_RS01815 5525b12ec4995b39ba92f7509d260a3a 519 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 427 511 4.5E-27 T 13-09-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 THL1_RS01815 5525b12ec4995b39ba92f7509d260a3a 519 SMART SM00928 425 471 5.1E-16 T 13-09-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 THL1_RS01815 5525b12ec4995b39ba92f7509d260a3a 519 SUPERFAMILY SSF142019 96 334 7.45E-83 T 13-09-2016 THL1_RS01815 5525b12ec4995b39ba92f7509d260a3a 519 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 145 315 1.9E-45 T 13-09-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain THL1_RS27825 a7f037bae60479c388b251b93aa24a46 402 SUPERFAMILY SSF102645 184 400 4.84E-77 T 13-09-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 THL1_RS27825 a7f037bae60479c388b251b93aa24a46 402 PANTHER PTHR14359:SF20 2 401 8.5E-195 T 13-09-2016 THL1_RS27825 a7f037bae60479c388b251b93aa24a46 402 Pfam PF02441 Flavoprotein 7 135 1.0E-34 T 13-09-2016 IPR003382 Flavoprotein GO:0003824 THL1_RS27825 a7f037bae60479c388b251b93aa24a46 402 SUPERFAMILY SSF52507 1 178 2.35E-61 T 13-09-2016 IPR003382 Flavoprotein GO:0003824 THL1_RS27825 a7f037bae60479c388b251b93aa24a46 402 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 6 395 5.8E-145 T 13-09-2016 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|UniPathway: UPA00241|UniPathway: UPA00241 THL1_RS27825 a7f037bae60479c388b251b93aa24a46 402 Gene3D G3DSA:3.40.50.1950 2 186 1.7E-66 T 13-09-2016 IPR003382 Flavoprotein GO:0003824 THL1_RS27825 a7f037bae60479c388b251b93aa24a46 402 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 186 370 3.9E-72 T 13-09-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 THL1_RS27825 a7f037bae60479c388b251b93aa24a46 402 Gene3D G3DSA:3.40.50.10300 187 401 9.9E-88 T 13-09-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 THL1_RS27825 a7f037bae60479c388b251b93aa24a46 402 PANTHER PTHR14359 2 401 8.5E-195 T 13-09-2016 THL1_RS25185 66ac967b779f9650fd0bcbcfd9488065 100 SUPERFAMILY SSF101386 1 99 1.44E-30 T 13-09-2016 THL1_RS25185 66ac967b779f9650fd0bcbcfd9488065 100 PANTHER PTHR14552 1 99 2.4E-27 T 13-09-2016 THL1_RS25185 66ac967b779f9650fd0bcbcfd9488065 100 PIRSF PIRSF029826 1 100 6.0E-36 T 13-09-2016 IPR011394 NTP Pyrophosphohydrolase MazG-related, RS21-C6 THL1_RS25185 66ac967b779f9650fd0bcbcfd9488065 100 Pfam PF12643 MazG-like family 31 97 2.6E-8 T 13-09-2016 IPR025984 MazG-like domain KEGG: 00240+3.6.1.12 THL1_RS25185 66ac967b779f9650fd0bcbcfd9488065 100 Gene3D G3DSA:1.10.287.1080 1 92 4.9E-19 T 13-09-2016 THL1_RS08820 111b9d09dd781ebccd4f678e36229f04 297 Gene3D G3DSA:3.40.190.10 272 296 6.7E-31 T 13-09-2016 THL1_RS08820 111b9d09dd781ebccd4f678e36229f04 297 Gene3D G3DSA:3.40.190.10 91 173 6.7E-31 T 13-09-2016 THL1_RS08820 111b9d09dd781ebccd4f678e36229f04 297 Pfam PF03466 LysR substrate binding domain 97 296 2.8E-31 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS08820 111b9d09dd781ebccd4f678e36229f04 297 Gene3D G3DSA:1.10.10.10 2 87 1.7E-28 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08820 111b9d09dd781ebccd4f678e36229f04 297 SUPERFAMILY SSF46785 4 86 3.27E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08820 111b9d09dd781ebccd4f678e36229f04 297 PANTHER PTHR30118:SF7 1 297 1.1E-127 T 13-09-2016 THL1_RS08820 111b9d09dd781ebccd4f678e36229f04 297 PANTHER PTHR30118 1 297 1.1E-127 T 13-09-2016 THL1_RS08820 111b9d09dd781ebccd4f678e36229f04 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 7.8E-14 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08820 111b9d09dd781ebccd4f678e36229f04 297 SUPERFAMILY SSF53850 91 295 7.6E-41 T 13-09-2016 THL1_RS08820 111b9d09dd781ebccd4f678e36229f04 297 Gene3D G3DSA:3.40.190.10 174 268 2.5E-25 T 13-09-2016 THL1_RS22950 c0fe736c88f37f2b14d79aa2963523a0 487 Gene3D G3DSA:3.40.309.10 269 459 2.5E-57 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS22950 c0fe736c88f37f2b14d79aa2963523a0 487 PANTHER PTHR11699:SF109 6 483 2.0E-253 T 13-09-2016 IPR015657 Aminobutyraldehyde dehydrogenase KEGG: 00330+1.2.1.19|KEGG: 00410+1.2.1.19|MetaCyc: PWY-2|MetaCyc: PWY-3|UniPathway: UPA00188 THL1_RS22950 c0fe736c88f37f2b14d79aa2963523a0 487 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS22950 c0fe736c88f37f2b14d79aa2963523a0 487 SUPERFAMILY SSF53720 8 484 1.83E-149 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS22950 c0fe736c88f37f2b14d79aa2963523a0 487 PANTHER PTHR11699 6 483 2.0E-253 T 13-09-2016 THL1_RS22950 c0fe736c88f37f2b14d79aa2963523a0 487 Gene3D G3DSA:3.40.605.10 11 268 4.0E-89 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS22950 c0fe736c88f37f2b14d79aa2963523a0 487 Pfam PF00171 Aldehyde dehydrogenase family 29 479 3.4E-156 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS07675 5d004a0d8f215e9517b9154c19d8cbfb 291 PANTHER PTHR23024:SF163 51 288 1.6E-49 T 13-09-2016 THL1_RS07675 5d004a0d8f215e9517b9154c19d8cbfb 291 PANTHER PTHR23024 51 288 1.6E-49 T 13-09-2016 THL1_RS07675 5d004a0d8f215e9517b9154c19d8cbfb 291 Pfam PF07859 alpha/beta hydrolase fold 76 162 2.5E-15 T 13-09-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 THL1_RS07675 5d004a0d8f215e9517b9154c19d8cbfb 291 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 140 155 - T 13-09-2016 IPR019826 Carboxylesterase type B, active site THL1_RS07675 5d004a0d8f215e9517b9154c19d8cbfb 291 SUPERFAMILY SSF53474 16 272 5.6E-46 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS07675 5d004a0d8f215e9517b9154c19d8cbfb 291 Gene3D G3DSA:3.40.50.1820 39 272 4.5E-49 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS27810 0dd2d617c3011623ec8870d2bdce3a17 78 Gene3D G3DSA:2.30.170.40 2 78 9.4E-38 T 13-09-2016 THL1_RS27810 0dd2d617c3011623ec8870d2bdce3a17 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 22.081 T 13-09-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS27810 0dd2d617c3011623ec8870d2bdce3a17 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 57 7.1E-29 T 13-09-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS27810 0dd2d617c3011623ec8870d2bdce3a17 78 Pfam PF00830 Ribosomal L28 family 3 61 3.6E-28 T 13-09-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 THL1_RS27810 0dd2d617c3011623ec8870d2bdce3a17 78 PANTHER PTHR13528 1 68 8.5E-37 T 13-09-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 THL1_RS27810 0dd2d617c3011623ec8870d2bdce3a17 78 SUPERFAMILY SSF143800 2 77 2.16E-31 T 13-09-2016 THL1_RS02225 265bb0d4ba00248cc3f948e563e9c5f1 155 SUPERFAMILY SSF54909 67 146 3.22E-15 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS02225 265bb0d4ba00248cc3f948e563e9c5f1 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 6.6E-11 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS02225 265bb0d4ba00248cc3f948e563e9c5f1 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 6.6E-11 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS02225 265bb0d4ba00248cc3f948e563e9c5f1 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 6.6E-11 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS02225 265bb0d4ba00248cc3f948e563e9c5f1 155 Gene3D G3DSA:1.10.10.10 5 56 3.1E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02225 265bb0d4ba00248cc3f948e563e9c5f1 155 PANTHER PTHR30154 1 141 2.1E-33 T 13-09-2016 THL1_RS02225 265bb0d4ba00248cc3f948e563e9c5f1 155 SMART SM00344 6 112 9.2E-20 T 13-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 THL1_RS02225 265bb0d4ba00248cc3f948e563e9c5f1 155 Pfam PF13404 AsnC-type helix-turn-helix domain 6 47 3.5E-14 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS02225 265bb0d4ba00248cc3f948e563e9c5f1 155 SUPERFAMILY SSF46785 6 61 4.51E-11 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02225 265bb0d4ba00248cc3f948e563e9c5f1 155 Pfam PF01037 Lrp/AsnC ligand binding domain 72 141 1.1E-12 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS02225 265bb0d4ba00248cc3f948e563e9c5f1 155 Gene3D G3DSA:3.30.70.920 70 141 2.2E-17 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS01395 92f36bd8e1778cd6fb50605bfce4e4f3 310 SUPERFAMILY SSF50956 13 303 7.45E-42 T 13-09-2016 THL1_RS01395 92f36bd8e1778cd6fb50605bfce4e4f3 310 Gene3D G3DSA:2.120.10.30 76 294 1.8E-18 T 13-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like THL1_RS01395 92f36bd8e1778cd6fb50605bfce4e4f3 310 Pfam PF06977 SdiA-regulated 54 300 8.1E-91 T 13-09-2016 IPR009722 SdiA-regulated THL1_RS21555 25fba7f064f83ca2e2343fa5613248c7 344 SMART SM00267 193 344 5.4E-7 T 13-09-2016 IPR000160 GGDEF domain THL1_RS21555 25fba7f064f83ca2e2343fa5613248c7 344 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 201 340 4.1E-12 T 13-09-2016 IPR000160 GGDEF domain THL1_RS21555 25fba7f064f83ca2e2343fa5613248c7 344 SUPERFAMILY SSF55073 209 340 1.96E-16 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS21555 25fba7f064f83ca2e2343fa5613248c7 344 Gene3D G3DSA:3.30.450.40 9 171 3.0E-21 T 13-09-2016 IPR029016 GAF domain-like THL1_RS21555 25fba7f064f83ca2e2343fa5613248c7 344 Pfam PF13185 GAF domain 25 160 1.0E-9 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS21555 25fba7f064f83ca2e2343fa5613248c7 344 SMART SM00065 27 169 5.3E-7 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS21555 25fba7f064f83ca2e2343fa5613248c7 344 Pfam PF00990 Diguanylate cyclase, GGDEF domain 205 340 9.0E-15 T 13-09-2016 IPR000160 GGDEF domain THL1_RS21555 25fba7f064f83ca2e2343fa5613248c7 344 Gene3D G3DSA:3.30.70.270 206 340 1.5E-18 T 13-09-2016 THL1_RS21555 25fba7f064f83ca2e2343fa5613248c7 344 SUPERFAMILY SSF55781 27 171 6.54E-23 T 13-09-2016 IPR029016 GAF domain-like THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 SUPERFAMILY SSF51120 1284 1473 7.15E-28 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 SUPERFAMILY SSF51120 1119 1256 1.62E-7 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1286 1302 0.91 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1222 1237 0.99 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1304 1320 0.0074 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1380 1396 0.017 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1203 1220 0.021 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1361 1377 0.91 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1397 1413 0.24 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1385 1403 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1367 1385 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1300 1318 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1376 1394 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1209 1227 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1291 1309 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 TIGRFAM TIGR03661 T1SS_VCA0849: type I secretion C-terminal target domain (VC_A0849 subclass) 1424 1492 3.7E-8 T 13-09-2016 IPR019960 Type I secretion C-terminal target domain, VC_A0849 subclass THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 PRINTS PR00313 NodO calcium binding signature 1210 1221 9.5E-10 T 13-09-2016 THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 PRINTS PR00313 NodO calcium binding signature 1304 1312 9.5E-10 T 13-09-2016 THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 PRINTS PR00313 NodO calcium binding signature 1380 1388 9.5E-10 T 13-09-2016 THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 PRINTS PR00313 NodO calcium binding signature 1407 1416 9.5E-10 T 13-09-2016 THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 Gene3D G3DSA:2.150.10.10 1285 1480 2.6E-28 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1394 1412 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS25380 73e4400b65fcbc36011a5487e75e3a1f 1505 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 92 167 0.0011 T 13-09-2016 IPR010221 VCBS repeat THL1_RS08340 bdab6cbfc1774fe66d8716712a4574b0 397 Pfam PF00155 Aminotransferase class I and II 30 393 3.3E-76 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS08340 bdab6cbfc1774fe66d8716712a4574b0 397 Gene3D G3DSA:3.40.640.10 48 316 1.4E-93 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS08340 bdab6cbfc1774fe66d8716712a4574b0 397 SUPERFAMILY SSF53383 1 397 1.55E-110 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS08340 bdab6cbfc1774fe66d8716712a4574b0 397 PANTHER PTHR11879:SF12 1 396 1.7E-237 T 13-09-2016 THL1_RS08340 bdab6cbfc1774fe66d8716712a4574b0 397 PANTHER PTHR11879 1 396 1.7E-237 T 13-09-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 THL1_RS08340 bdab6cbfc1774fe66d8716712a4574b0 397 PRINTS PR00799 Aspartate aminotransferase signature 176 195 9.7E-36 T 13-09-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 THL1_RS08340 bdab6cbfc1774fe66d8716712a4574b0 397 PRINTS PR00799 Aspartate aminotransferase signature 342 360 9.7E-36 T 13-09-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 THL1_RS08340 bdab6cbfc1774fe66d8716712a4574b0 397 PRINTS PR00799 Aspartate aminotransferase signature 274 299 9.7E-36 T 13-09-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 THL1_RS08340 bdab6cbfc1774fe66d8716712a4574b0 397 PRINTS PR00799 Aspartate aminotransferase signature 207 219 9.7E-36 T 13-09-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 THL1_RS15810 3c5fe2422377dee589937b52b1ad02a3 308 SUPERFAMILY SSF53850 89 296 9.41E-46 T 13-09-2016 THL1_RS15810 3c5fe2422377dee589937b52b1ad02a3 308 SUPERFAMILY SSF46785 5 86 9.95E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS15810 3c5fe2422377dee589937b52b1ad02a3 308 Gene3D G3DSA:3.40.190.10 92 176 1.0E-23 T 13-09-2016 THL1_RS15810 3c5fe2422377dee589937b52b1ad02a3 308 Pfam PF03466 LysR substrate binding domain 88 292 1.8E-41 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS15810 3c5fe2422377dee589937b52b1ad02a3 308 PANTHER PTHR30537:SF5 1 298 1.5E-114 T 13-09-2016 THL1_RS15810 3c5fe2422377dee589937b52b1ad02a3 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.1E-18 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS15810 3c5fe2422377dee589937b52b1ad02a3 308 Gene3D G3DSA:3.40.190.10 177 260 2.3E-21 T 13-09-2016 THL1_RS15810 3c5fe2422377dee589937b52b1ad02a3 308 PANTHER PTHR30537 1 298 1.5E-114 T 13-09-2016 THL1_RS15810 3c5fe2422377dee589937b52b1ad02a3 308 Gene3D G3DSA:1.10.10.10 4 83 3.9E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS15810 3c5fe2422377dee589937b52b1ad02a3 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.0E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS15810 3c5fe2422377dee589937b52b1ad02a3 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.0E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS15810 3c5fe2422377dee589937b52b1ad02a3 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.0E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS18265 dbb8adaf36441674f31024a41c4fd118 326 Gene3D G3DSA:3.40.50.1820 36 280 4.8E-37 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS18265 dbb8adaf36441674f31024a41c4fd118 326 Pfam PF12146 Serine aminopeptidase, S33 78 280 1.2E-14 T 13-09-2016 IPR022742 Serine aminopeptidase, S33 THL1_RS18265 dbb8adaf36441674f31024a41c4fd118 326 PANTHER PTHR10992 79 280 1.3E-12 T 13-09-2016 THL1_RS18265 dbb8adaf36441674f31024a41c4fd118 326 SUPERFAMILY SSF53474 23 172 2.34E-33 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS18265 dbb8adaf36441674f31024a41c4fd118 326 SUPERFAMILY SSF53474 233 294 2.34E-33 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS18190 8cd762464be26fce096b15d58756b99a 240 SMART SM00895 90 217 8.5E-27 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS18190 8cd762464be26fce096b15d58756b99a 240 Gene3D G3DSA:1.20.120.530 83 227 1.9E-33 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS18190 8cd762464be26fce096b15d58756b99a 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 80 5.3E-16 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS18190 8cd762464be26fce096b15d58756b99a 240 PANTHER PTHR11751 20 106 2.4E-58 T 13-09-2016 THL1_RS18190 8cd762464be26fce096b15d58756b99a 240 SUPERFAMILY SSF48008 87 225 7.32E-29 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS18190 8cd762464be26fce096b15d58756b99a 240 Pfam PF07729 FCD domain 90 216 4.4E-30 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS18190 8cd762464be26fce096b15d58756b99a 240 Gene3D G3DSA:1.10.10.10 8 80 2.4E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS18190 8cd762464be26fce096b15d58756b99a 240 PANTHER PTHR11751:SF426 20 106 2.4E-58 T 13-09-2016 THL1_RS18190 8cd762464be26fce096b15d58756b99a 240 SMART SM00345 22 80 2.6E-13 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS18190 8cd762464be26fce096b15d58756b99a 240 SUPERFAMILY SSF46785 12 108 5.82E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS03505 79be86452a14471237e00b76db949f08 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.8E-66 T 13-09-2016 IPR023798 Ribosomal protein S7 domain THL1_RS03505 79be86452a14471237e00b76db949f08 156 SUPERFAMILY SSF47973 6 149 1.7E-60 T 13-09-2016 IPR023798 Ribosomal protein S7 domain THL1_RS03505 79be86452a14471237e00b76db949f08 156 Gene3D G3DSA:1.10.455.10 8 156 8.7E-66 T 13-09-2016 IPR023798 Ribosomal protein S7 domain THL1_RS03505 79be86452a14471237e00b76db949f08 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 36.564 T 13-09-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 THL1_RS03505 79be86452a14471237e00b76db949f08 156 PIRSF PIRSF002122 2 156 4.8E-61 T 13-09-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 THL1_RS03505 79be86452a14471237e00b76db949f08 156 PANTHER PTHR11205 1 156 6.5E-88 T 13-09-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 THL1_RS03505 79be86452a14471237e00b76db949f08 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 13-09-2016 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 THL1_RS03505 79be86452a14471237e00b76db949f08 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 155 2.9E-68 T 13-09-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 THL1_RS09350 c9cad467137bc7b1d263bffe95a36a74 648 SMART SM00304 171 223 4.3E-6 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS09350 c9cad467137bc7b1d263bffe95a36a74 648 SUPERFAMILY SSF55073 241 397 1.18E-19 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS09350 c9cad467137bc7b1d263bffe95a36a74 648 SUPERFAMILY SSF141868 414 647 5.23E-43 T 13-09-2016 IPR001633 EAL domain THL1_RS09350 c9cad467137bc7b1d263bffe95a36a74 648 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 233 390 1.2E-12 T 13-09-2016 IPR000160 GGDEF domain THL1_RS09350 c9cad467137bc7b1d263bffe95a36a74 648 SMART SM00267 225 398 2.2E-15 T 13-09-2016 IPR000160 GGDEF domain THL1_RS09350 c9cad467137bc7b1d263bffe95a36a74 648 Gene3D G3DSA:3.20.20.450 412 647 1.1E-40 T 13-09-2016 IPR001633 EAL domain THL1_RS09350 c9cad467137bc7b1d263bffe95a36a74 648 Pfam PF00672 HAMP domain 152 219 2.5E-10 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS09350 c9cad467137bc7b1d263bffe95a36a74 648 Pfam PF00563 EAL domain 415 643 1.8E-45 T 13-09-2016 IPR001633 EAL domain THL1_RS09350 c9cad467137bc7b1d263bffe95a36a74 648 Gene3D G3DSA:3.30.70.270 238 392 3.9E-22 T 13-09-2016 THL1_RS09350 c9cad467137bc7b1d263bffe95a36a74 648 PANTHER PTHR33121 412 645 3.3E-27 T 13-09-2016 THL1_RS09350 c9cad467137bc7b1d263bffe95a36a74 648 SMART SM00052 408 648 4.3E-11 T 13-09-2016 IPR001633 EAL domain THL1_RS09350 c9cad467137bc7b1d263bffe95a36a74 648 PANTHER PTHR33121:SF10 412 645 3.3E-27 T 13-09-2016 THL1_RS09350 c9cad467137bc7b1d263bffe95a36a74 648 Pfam PF16448 LapD/MoxY periplasmic domain 25 145 6.8E-39 T 13-09-2016 IPR032244 LapD/MoxY, periplasmic domain THL1_RS09350 c9cad467137bc7b1d263bffe95a36a74 648 Pfam PF00990 Diguanylate cyclase, GGDEF domain 236 390 3.0E-21 T 13-09-2016 IPR000160 GGDEF domain THL1_RS15675 c969b7699a585b886cd79ff61bd29b6a 306 PANTHER PTHR11019 74 305 3.0E-33 T 13-09-2016 THL1_RS15675 c969b7699a585b886cd79ff61bd29b6a 306 Pfam PF14525 AraC-binding-like domain 19 187 1.0E-20 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS15675 c969b7699a585b886cd79ff61bd29b6a 306 Pfam PF12833 Helix-turn-helix domain 222 302 2.3E-19 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS15675 c969b7699a585b886cd79ff61bd29b6a 306 SUPERFAMILY SSF46689 252 303 1.84E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15675 c969b7699a585b886cd79ff61bd29b6a 306 Gene3D G3DSA:1.10.10.60 194 251 1.9E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15675 c969b7699a585b886cd79ff61bd29b6a 306 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 269 284 3.9E-6 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS15675 c969b7699a585b886cd79ff61bd29b6a 306 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 284 300 3.9E-6 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS15675 c969b7699a585b886cd79ff61bd29b6a 306 Gene3D G3DSA:1.10.10.60 252 303 1.3E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15675 c969b7699a585b886cd79ff61bd29b6a 306 PANTHER PTHR11019:SF50 74 305 3.0E-33 T 13-09-2016 THL1_RS15675 c969b7699a585b886cd79ff61bd29b6a 306 SMART SM00342 216 300 3.0E-24 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS04855 8470c8eef9b69adf9aefee6b74433c33 312 Gene3D G3DSA:3.40.50.620 1 179 5.6E-68 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS04855 8470c8eef9b69adf9aefee6b74433c33 312 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 20 306 1.3E-94 T 13-09-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 THL1_RS04855 8470c8eef9b69adf9aefee6b74433c33 312 PANTHER PTHR22749 1 306 7.3E-134 T 13-09-2016 IPR023468 Riboflavin kinase KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|UniPathway: UPA00276 THL1_RS04855 8470c8eef9b69adf9aefee6b74433c33 312 SUPERFAMILY SSF82114 174 307 2.62E-43 T 13-09-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 THL1_RS04855 8470c8eef9b69adf9aefee6b74433c33 312 Gene3D G3DSA:2.40.30.30 180 307 5.9E-38 T 13-09-2016 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 THL1_RS04855 8470c8eef9b69adf9aefee6b74433c33 312 PIRSF PIRSF004491 1 312 5.9E-104 T 13-09-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 THL1_RS04855 8470c8eef9b69adf9aefee6b74433c33 312 Pfam PF01687 Riboflavin kinase 184 305 1.3E-36 T 13-09-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 THL1_RS04855 8470c8eef9b69adf9aefee6b74433c33 312 SMART SM00904 183 307 2.5E-57 T 13-09-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 THL1_RS04855 8470c8eef9b69adf9aefee6b74433c33 312 PANTHER PTHR22749:SF0 1 306 7.3E-134 T 13-09-2016 THL1_RS04855 8470c8eef9b69adf9aefee6b74433c33 312 Pfam PF06574 FAD synthetase 12 167 3.5E-56 T 13-09-2016 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 THL1_RS04855 8470c8eef9b69adf9aefee6b74433c33 312 SUPERFAMILY SSF52374 15 175 5.07E-34 T 13-09-2016 THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 Gene3D G3DSA:3.40.50.720 2 253 7.0E-83 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 190 5.5E-4 T 13-09-2016 THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 6.9E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 6.9E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 6.9E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.1E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.1E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.1E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.1E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.1E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.1E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 PANTHER PTHR24322:SF328 11 139 3.1E-51 T 13-09-2016 THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 PANTHER PTHR24322:SF328 155 187 3.1E-51 T 13-09-2016 THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 252 5.1E-61 T 13-09-2016 THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 SUPERFAMILY SSF51735 6 253 2.05E-80 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 PANTHER PTHR24322 11 139 3.1E-51 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17465 a9a5f0b39215293fd69d71d527703fcb 255 PANTHER PTHR24322 155 187 3.1E-51 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS02025 886b0f18343f5600a37bf7a8d88d6996 176 PANTHER PTHR23091 1 149 2.9E-21 T 13-09-2016 THL1_RS02025 886b0f18343f5600a37bf7a8d88d6996 176 Gene3D G3DSA:3.40.630.30 4 172 5.3E-38 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS02025 886b0f18343f5600a37bf7a8d88d6996 176 SUPERFAMILY SSF55729 3 171 4.51E-33 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS02025 886b0f18343f5600a37bf7a8d88d6996 176 Pfam PF00583 Acetyltransferase (GNAT) family 69 146 3.4E-14 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS11725 77e677608a079b970ba6d3d205b31b94 473 SUPERFAMILY SSF53955 283 433 1.6E-29 T 13-09-2016 IPR023346 Lysozyme-like domain THL1_RS11725 77e677608a079b970ba6d3d205b31b94 473 SMART SM00062 47 286 9.9E-4 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS11725 77e677608a079b970ba6d3d205b31b94 473 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 65 268 5.5E-9 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS11725 77e677608a079b970ba6d3d205b31b94 473 Gene3D G3DSA:3.40.190.10 140 234 3.0E-5 T 13-09-2016 THL1_RS11725 77e677608a079b970ba6d3d205b31b94 473 SUPERFAMILY SSF53850 46 284 1.4E-24 T 13-09-2016 THL1_RS11725 77e677608a079b970ba6d3d205b31b94 473 Gene3D G3DSA:1.10.530.10 284 457 7.1E-37 T 13-09-2016 THL1_RS11725 77e677608a079b970ba6d3d205b31b94 473 PANTHER PTHR21666 287 468 1.9E-65 T 13-09-2016 THL1_RS11725 77e677608a079b970ba6d3d205b31b94 473 Gene3D G3DSA:3.40.190.10 245 273 8.0E-5 T 13-09-2016 THL1_RS11725 77e677608a079b970ba6d3d205b31b94 473 Gene3D G3DSA:3.40.190.10 62 139 8.0E-5 T 13-09-2016 THL1_RS11725 77e677608a079b970ba6d3d205b31b94 473 PANTHER PTHR21666:SF206 287 468 1.9E-65 T 13-09-2016 THL1_RS11725 77e677608a079b970ba6d3d205b31b94 473 Pfam PF01464 Transglycosylase SLT domain 309 418 3.4E-15 T 13-09-2016 IPR008258 Transglycosylase SLT domain 1 THL1_RS00080 7b7c056422e458e3fe8d937fb2fa7a89 88 Gene3D G3DSA:2.40.10.220 1 84 6.5E-4 T 13-09-2016 THL1_RS00080 7b7c056422e458e3fe8d937fb2fa7a89 88 SUPERFAMILY SSF141371 1 86 1.53E-9 T 13-09-2016 THL1_RS00080 7b7c056422e458e3fe8d937fb2fa7a89 88 Pfam PF07238 PilZ domain 4 87 3.5E-10 T 13-09-2016 IPR009875 PilZ domain GO:0035438 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 Gene3D G3DSA:3.10.20.30 11 88 2.6E-22 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 Pfam PF00175 Oxidoreductase NAD-binding domain 214 318 6.8E-19 T 13-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 13-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 Gene3D G3DSA:2.40.30.10 109 201 1.4E-25 T 13-09-2016 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 SUPERFAMILY SSF52343 206 337 1.31E-35 T 13-09-2016 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 PANTHER PTHR19370 22 336 4.9E-117 T 13-09-2016 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 PRINTS PR00410 Phenol hydroxylase reductase family signature 213 232 1.7E-20 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 PRINTS PR00410 Phenol hydroxylase reductase family signature 137 149 1.7E-20 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 PRINTS PR00410 Phenol hydroxylase reductase family signature 154 161 1.7E-20 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 PRINTS PR00410 Phenol hydroxylase reductase family signature 198 207 1.7E-20 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 PRINTS PR00410 Phenol hydroxylase reductase family signature 304 312 1.7E-20 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 85 3.0E-17 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 Gene3D G3DSA:3.40.50.80 209 337 1.2E-35 T 13-09-2016 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 SUPERFAMILY SSF54292 2 88 2.75E-23 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 Pfam PF00970 Oxidoreductase FAD-binding domain 110 204 3.6E-22 T 13-09-2016 IPR008333 Oxidoreductase, FAD-binding domain THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 PANTHER PTHR19370:SF128 22 336 4.9E-117 T 13-09-2016 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 154 161 3.2E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 304 312 3.2E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 239 248 3.2E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 213 232 3.2E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS07715 17d635a1835d8786e6c0f6d93d49aa30 341 SUPERFAMILY SSF63380 109 204 1.23E-22 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS14225 4a8b1083b3640729fbb29234daca90b6 292 SMART SM00062 31 281 0.002 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS14225 4a8b1083b3640729fbb29234daca90b6 292 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 127 279 7.8E-8 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS14225 4a8b1083b3640729fbb29234daca90b6 292 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 32 80 2.1E-9 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS14225 4a8b1083b3640729fbb29234daca90b6 292 Gene3D G3DSA:3.40.190.10 29 77 4.2E-17 T 13-09-2016 THL1_RS14225 4a8b1083b3640729fbb29234daca90b6 292 Gene3D G3DSA:3.40.190.10 192 278 4.2E-17 T 13-09-2016 THL1_RS14225 4a8b1083b3640729fbb29234daca90b6 292 SUPERFAMILY SSF53850 23 278 1.27E-24 T 13-09-2016 THL1_RS15715 ab87f899f39b14a44be344c5d4efe105 401 Gene3D G3DSA:3.40.47.10 200 282 3.2E-69 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15715 ab87f899f39b14a44be344c5d4efe105 401 Gene3D G3DSA:3.40.47.10 3 125 3.2E-69 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15715 ab87f899f39b14a44be344c5d4efe105 401 TIGRFAM TIGR02430 pcaF: 3-oxoadipyl-CoA thiolase 3 401 3.3E-224 T 13-09-2016 IPR012793 Beta-ketoadipyl CoA thiolase GO:0016747|GO:0019619 KEGG: 00250+2.3.1.17|KEGG: 00360+2.3.1.174|KEGG: 00362+2.3.1.174|MetaCyc: PWY-1361|MetaCyc: PWY-2361|MetaCyc: PWY-6185 THL1_RS15715 ab87f899f39b14a44be344c5d4efe105 401 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 13-09-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 THL1_RS15715 ab87f899f39b14a44be344c5d4efe105 401 Gene3D G3DSA:3.40.47.10 154 199 1.0E-61 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15715 ab87f899f39b14a44be344c5d4efe105 401 Gene3D G3DSA:3.40.47.10 283 400 1.0E-61 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15715 ab87f899f39b14a44be344c5d4efe105 401 Pfam PF02803 Thiolase, C-terminal domain 277 400 5.3E-46 T 13-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THL1_RS15715 ab87f899f39b14a44be344c5d4efe105 401 SUPERFAMILY SSF53901 3 276 4.14E-82 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15715 ab87f899f39b14a44be344c5d4efe105 401 PIRSF PIRSF000429 1 401 8.1E-137 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS15715 ab87f899f39b14a44be344c5d4efe105 401 Pfam PF00108 Thiolase, N-terminal domain 5 268 6.5E-76 T 13-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THL1_RS15715 ab87f899f39b14a44be344c5d4efe105 401 SUPERFAMILY SSF53901 278 400 5.26E-46 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15715 ab87f899f39b14a44be344c5d4efe105 401 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 399 1.0E-138 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS15715 ab87f899f39b14a44be344c5d4efe105 401 PANTHER PTHR18919 1 401 1.0E-237 T 13-09-2016 THL1_RS15715 ab87f899f39b14a44be344c5d4efe105 401 PANTHER PTHR18919:SF91 1 401 1.0E-237 T 13-09-2016 THL1_RS15715 ab87f899f39b14a44be344c5d4efe105 401 ProSitePatterns PS00099 Thiolases active site. 382 395 - T 13-09-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 THL1_RS15715 ab87f899f39b14a44be344c5d4efe105 401 ProSitePatterns PS00737 Thiolases signature 2. 347 363 - T 13-09-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 THL1_RS13720 01fab68388ed20b92b69ffad0a6cdc14 257 PANTHER PTHR11820:SF8 15 256 1.6E-155 T 13-09-2016 THL1_RS13720 01fab68388ed20b92b69ffad0a6cdc14 257 Gene3D G3DSA:3.90.850.10 39 248 2.0E-75 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS13720 01fab68388ed20b92b69ffad0a6cdc14 257 TIGRFAM TIGR02303 HpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit 2 246 1.2E-121 T 13-09-2016 IPR012684 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit GO:0008704|GO:0018800|GO:1901023 KEGG: 00350+5.3.3.10+4.1.1.68|UniPathway: UPA00208|UniPathway: UPA00208 THL1_RS13720 01fab68388ed20b92b69ffad0a6cdc14 257 PANTHER PTHR11820 15 256 1.6E-155 T 13-09-2016 THL1_RS13720 01fab68388ed20b92b69ffad0a6cdc14 257 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 46 244 2.7E-57 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS13720 01fab68388ed20b92b69ffad0a6cdc14 257 SUPERFAMILY SSF56529 39 249 6.15E-71 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS00520 006af59190982ad640a0df9026e5ef94 373 PANTHER PTHR10160 3 369 2.6E-169 T 13-09-2016 THL1_RS00520 006af59190982ad640a0df9026e5ef94 373 SMART SM01003 4 136 1.3E-63 T 13-09-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal THL1_RS00520 006af59190982ad640a0df9026e5ef94 373 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 370 1.1E-73 T 13-09-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain THL1_RS00520 006af59190982ad640a0df9026e5ef94 373 SUPERFAMILY SSF51735 136 317 6.58E-36 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS00520 006af59190982ad640a0df9026e5ef94 373 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 3.4E-41 T 13-09-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal THL1_RS00520 006af59190982ad640a0df9026e5ef94 373 Gene3D G3DSA:3.40.50.1770 2 186 2.7E-59 T 13-09-2016 THL1_RS00520 006af59190982ad640a0df9026e5ef94 373 SUPERFAMILY SSF52283 2 167 5.02E-49 T 13-09-2016 THL1_RS00520 006af59190982ad640a0df9026e5ef94 373 Gene3D G3DSA:3.40.50.1770 187 368 1.1E-40 T 13-09-2016 THL1_RS00520 006af59190982ad640a0df9026e5ef94 373 SMART SM01002 145 314 2.4E-83 T 13-09-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 Gene3D G3DSA:1.10.287.130 791 859 8.5E-13 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 SUPERFAMILY SSF47384 779 864 2.16E-15 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 SMART SM00448 1039 1152 2.5E-11 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 PANTHER PTHR24423:SF439 634 768 7.3E-222 T 13-09-2016 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 PANTHER PTHR24423:SF439 15 63 7.3E-222 T 13-09-2016 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 PRINTS PR00344 Bacterial sensor protein C-terminal signature 977 995 1.2E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 PRINTS PR00344 Bacterial sensor protein C-terminal signature 942 956 1.2E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 PRINTS PR00344 Bacterial sensor protein C-terminal signature 960 970 1.2E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1001 1014 1.2E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 PANTHER PTHR24423 634 768 7.3E-222 T 13-09-2016 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 PANTHER PTHR24423 15 63 7.3E-222 T 13-09-2016 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 PANTHER PTHR24423 182 201 7.3E-222 T 13-09-2016 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 Pfam PF12860 PAS fold 642 755 1.1E-45 T 13-09-2016 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 SMART SM00387 907 1017 3.8E-25 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 PANTHER PTHR24423:SF439 182 201 7.3E-222 T 13-09-2016 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 SUPERFAMILY SSF52172 1037 1157 1.07E-19 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 SUPERFAMILY SSF55785 627 749 2.66E-9 T 13-09-2016 IPR000014 PAS domain THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 Gene3D G3DSA:3.30.565.10 865 1022 1.8E-36 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 PANTHER PTHR24423:SF439 794 1156 7.3E-222 T 13-09-2016 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 PANTHER PTHR24423 794 1156 7.3E-222 T 13-09-2016 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 Pfam PF00512 His Kinase A (phospho-acceptor) domain 796 863 3.9E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 SUPERFAMILY SSF55874 853 1019 1.44E-37 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 Pfam PF00072 Response regulator receiver domain 1041 1152 6.8E-10 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 Gene3D G3DSA:3.40.50.2300 1033 1156 4.4E-19 T 13-09-2016 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 Gene3D G3DSA:3.30.450.20 627 749 7.4E-14 T 13-09-2016 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 SMART SM00388 796 863 8.8E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS06600 59a8ce5eb88a7b0321a6f843f3e750b0 1159 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 910 1016 3.4E-17 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS12140 02e3d1f102cdabc8bec7e1a2143b9e9d 168 PANTHER PTHR30173:SF6 10 167 1.1E-36 T 13-09-2016 THL1_RS12140 02e3d1f102cdabc8bec7e1a2143b9e9d 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 153 1.7E-19 T 13-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS12140 02e3d1f102cdabc8bec7e1a2143b9e9d 168 Gene3D G3DSA:1.10.1740.10 9 75 5.8E-15 T 13-09-2016 THL1_RS12140 02e3d1f102cdabc8bec7e1a2143b9e9d 168 PANTHER PTHR30173 10 167 1.1E-36 T 13-09-2016 THL1_RS12140 02e3d1f102cdabc8bec7e1a2143b9e9d 168 SUPERFAMILY SSF88946 9 81 6.28E-14 T 13-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS12140 02e3d1f102cdabc8bec7e1a2143b9e9d 168 Pfam PF04542 Sigma-70 region 2 10 74 3.5E-9 T 13-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS12140 02e3d1f102cdabc8bec7e1a2143b9e9d 168 Pfam PF08281 Sigma-70, region 4 99 151 5.7E-16 T 13-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS12140 02e3d1f102cdabc8bec7e1a2143b9e9d 168 SUPERFAMILY SSF88659 94 155 1.11E-16 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS12140 02e3d1f102cdabc8bec7e1a2143b9e9d 168 Gene3D G3DSA:1.10.10.10 93 157 1.5E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS15430 8908862c8f0bbe99fe077ae6d0ad7ed0 398 PANTHER PTHR23523:SF1 16 393 5.0E-163 T 13-09-2016 THL1_RS15430 8908862c8f0bbe99fe077ae6d0ad7ed0 398 PANTHER PTHR23523 16 393 5.0E-163 T 13-09-2016 THL1_RS15430 8908862c8f0bbe99fe077ae6d0ad7ed0 398 Gene3D G3DSA:1.20.1250.20 203 378 2.7E-19 T 13-09-2016 THL1_RS15430 8908862c8f0bbe99fe077ae6d0ad7ed0 398 Pfam PF07690 Major Facilitator Superfamily 30 346 1.7E-24 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS15430 8908862c8f0bbe99fe077ae6d0ad7ed0 398 SUPERFAMILY SSF103473 9 382 4.84E-41 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS15430 8908862c8f0bbe99fe077ae6d0ad7ed0 398 Gene3D G3DSA:1.20.1250.20 14 182 1.0E-8 T 13-09-2016 THL1_RS07865 1811b4eb64716112f0927fa5156a9791 235 SMART SM00895 88 215 3.2E-13 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS07865 1811b4eb64716112f0927fa5156a9791 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 78 9.3E-17 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS07865 1811b4eb64716112f0927fa5156a9791 235 SUPERFAMILY SSF48008 95 223 1.99E-21 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS07865 1811b4eb64716112f0927fa5156a9791 235 SMART SM00345 20 78 8.0E-15 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS07865 1811b4eb64716112f0927fa5156a9791 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 7.8E-5 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS07865 1811b4eb64716112f0927fa5156a9791 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 7.8E-5 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS07865 1811b4eb64716112f0927fa5156a9791 235 SUPERFAMILY SSF46785 17 88 1.51E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07865 1811b4eb64716112f0927fa5156a9791 235 Pfam PF07729 FCD domain 94 212 1.2E-20 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS07865 1811b4eb64716112f0927fa5156a9791 235 PANTHER PTHR11751:SF362 20 104 1.2E-21 T 13-09-2016 THL1_RS07865 1811b4eb64716112f0927fa5156a9791 235 Gene3D G3DSA:1.10.10.10 8 80 7.9E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07865 1811b4eb64716112f0927fa5156a9791 235 PANTHER PTHR11751 20 104 1.2E-21 T 13-09-2016 THL1_RS07865 1811b4eb64716112f0927fa5156a9791 235 Gene3D G3DSA:1.20.120.530 95 227 1.3E-23 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS26160 bdf29ee04e0f9746cb958fddda81f03e 271 PIRSF PIRSF037318 2 266 6.0E-130 T 13-09-2016 IPR017172 Lipopolysaccharide core heptose(I) kinase rfaP GO:0009103|GO:0016301 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.-|UniPathway: UPA00958 THL1_RS26160 bdf29ee04e0f9746cb958fddda81f03e 271 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 21 231 3.0E-66 T 13-09-2016 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 THL1_RS26160 bdf29ee04e0f9746cb958fddda81f03e 271 SUPERFAMILY SSF56112 34 230 4.17E-10 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS03570 b75bc2c5e13b0056b7d675fa980f3d9b 88 SUPERFAMILY SSF50249 9 85 7.28E-33 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS03570 b75bc2c5e13b0056b7d675fa980f3d9b 88 PANTHER PTHR10744 9 87 3.1E-43 T 13-09-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03570 b75bc2c5e13b0056b7d675fa980f3d9b 88 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 9 79 2.0E-37 T 13-09-2016 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03570 b75bc2c5e13b0056b7d675fa980f3d9b 88 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 6 84 26.504 T 13-09-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03570 b75bc2c5e13b0056b7d675fa980f3d9b 88 PRINTS PR00973 Ribosomal protein S17 family signature 59 69 1.9E-13 T 13-09-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03570 b75bc2c5e13b0056b7d675fa980f3d9b 88 PRINTS PR00973 Ribosomal protein S17 family signature 69 76 1.9E-13 T 13-09-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03570 b75bc2c5e13b0056b7d675fa980f3d9b 88 PRINTS PR00973 Ribosomal protein S17 family signature 27 50 1.9E-13 T 13-09-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03570 b75bc2c5e13b0056b7d675fa980f3d9b 88 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 9 79 3.0E-34 T 13-09-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03570 b75bc2c5e13b0056b7d675fa980f3d9b 88 Gene3D G3DSA:2.40.50.140 9 85 7.4E-36 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS03570 b75bc2c5e13b0056b7d675fa980f3d9b 88 Pfam PF00366 Ribosomal protein S17 13 80 8.0E-34 T 13-09-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS22980 1d75c46b5794bf909d274839cce93392 158 Pfam PF07366 SnoaL-like polyketide cyclase 29 156 3.7E-21 T 13-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain THL1_RS22980 1d75c46b5794bf909d274839cce93392 158 Gene3D G3DSA:3.10.450.50 14 157 2.0E-27 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS22980 1d75c46b5794bf909d274839cce93392 158 SUPERFAMILY SSF54427 25 158 7.53E-28 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS15310 5f143f0d6326bb36d5e850dbff615949 324 PANTHER PTHR13748:SF43 1 321 7.3E-127 T 13-09-2016 THL1_RS15310 5f143f0d6326bb36d5e850dbff615949 324 PANTHER PTHR13748 1 321 7.3E-127 T 13-09-2016 THL1_RS15310 5f143f0d6326bb36d5e850dbff615949 324 SUPERFAMILY SSF52540 6 195 2.66E-37 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15310 5f143f0d6326bb36d5e850dbff615949 324 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 229 322 1.2E-18 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS15310 5f143f0d6326bb36d5e850dbff615949 324 Gene3D G3DSA:3.30.1220.10 227 322 9.9E-31 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS15310 5f143f0d6326bb36d5e850dbff615949 324 SUPERFAMILY SSF90002 229 322 1.7E-22 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS15310 5f143f0d6326bb36d5e850dbff615949 324 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 8 186 7.9E-50 T 13-09-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain THL1_RS15310 5f143f0d6326bb36d5e850dbff615949 324 Gene3D G3DSA:3.40.50.300 6 206 1.6E-67 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15310 5f143f0d6326bb36d5e850dbff615949 324 SMART SM00833 229 323 5.7E-11 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 SUPERFAMILY SSF46977 454 590 1.57E-48 T 13-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 44 53 - T 13-09-2016 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 10 590 2.4E-255 T 13-09-2016 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 Gene3D G3DSA:4.10.80.40 558 590 9.6E-22 T 13-09-2016 THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 Gene3D G3DSA:3.90.700.10 246 351 3.2E-39 T 13-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 Gene3D G3DSA:3.50.50.60 353 426 3.0E-117 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 Gene3D G3DSA:3.50.50.60 4 245 3.0E-117 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 PIRSF PIRSF000171 1 580 5.2E-49 T 13-09-2016 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 5.5E-5 T 13-09-2016 THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 370 392 5.5E-5 T 13-09-2016 THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 PANTHER PTHR11632 3 576 0.0 T 13-09-2016 THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 8 590 0.0 T 13-09-2016 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 Pfam PF00890 FAD binding domain 10 407 7.1E-118 T 13-09-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 Gene3D G3DSA:1.20.58.100 451 557 7.1E-40 T 13-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 Pfam PF02910 Fumarate reductase flavoprotein C-term 463 590 5.4E-40 T 13-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 SUPERFAMILY SSF56425 240 358 9.72E-40 T 13-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 SUPERFAMILY SSF51905 6 262 1.93E-73 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 SUPERFAMILY SSF51905 361 427 1.93E-73 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10860 cffe443d9f908456ae57d8c5639b225a 590 PANTHER PTHR11632:SF5 3 576 0.0 T 13-09-2016 THL1_RS09085 2a9d74b56ae1d8bf3592edc43386b2d9 184 PRINTS PR01011 Glutathione peroxidase family signature 82 98 5.0E-9 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS09085 2a9d74b56ae1d8bf3592edc43386b2d9 184 PRINTS PR01011 Glutathione peroxidase family signature 142 151 5.0E-9 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS09085 2a9d74b56ae1d8bf3592edc43386b2d9 184 PRINTS PR01011 Glutathione peroxidase family signature 47 64 5.0E-9 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS09085 2a9d74b56ae1d8bf3592edc43386b2d9 184 SUPERFAMILY SSF52833 28 180 7.69E-44 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS09085 2a9d74b56ae1d8bf3592edc43386b2d9 184 PANTHER PTHR11592 9 184 1.3E-85 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS09085 2a9d74b56ae1d8bf3592edc43386b2d9 184 PIRSF PIRSF000303 2 183 2.9E-58 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS09085 2a9d74b56ae1d8bf3592edc43386b2d9 184 Gene3D G3DSA:3.40.30.10 29 181 3.3E-46 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS09085 2a9d74b56ae1d8bf3592edc43386b2d9 184 ProSitePatterns PS00460 Glutathione peroxidases active site. 49 64 - T 13-09-2016 IPR029759 Glutathione peroxidase active site THL1_RS09085 2a9d74b56ae1d8bf3592edc43386b2d9 184 Pfam PF00255 Glutathione peroxidase 45 134 2.9E-24 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS09085 2a9d74b56ae1d8bf3592edc43386b2d9 184 PANTHER PTHR11592:SF31 9 184 1.3E-85 T 13-09-2016 THL1_RS00780 341e8491de2b993be709e6ac4c6bbcef 205 Hamap MF_00650 Phosphoribosyl-dephospho-CoA transferase [mdcG]. 4 202 34.394 T 13-09-2016 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 THL1_RS00780 341e8491de2b993be709e6ac4c6bbcef 205 TIGRFAM TIGR03135 malonate_mdcG: malonate decarboxylase holo-[acyl-carrier-protein] synthase 7 196 2.5E-55 T 13-09-2016 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 THL1_RS00780 341e8491de2b993be709e6ac4c6bbcef 205 Pfam PF10620 Phosphoribosyl-dephospho-CoA transferase MdcG 7 197 1.3E-58 T 13-09-2016 IPR017557 Phosphoribosyl-dephospho-CoA transferase GO:0016779 MetaCyc: PWY-5796 THL1_RS16555 4c9c7088fef48ab846c2fe0223f8800c 310 SMART SM00382 30 228 3.9E-10 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS16555 4c9c7088fef48ab846c2fe0223f8800c 310 Gene3D G3DSA:3.40.50.300 2 233 1.2E-69 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16555 4c9c7088fef48ab846c2fe0223f8800c 310 PANTHER PTHR24220:SF305 6 302 2.1E-169 T 13-09-2016 THL1_RS16555 4c9c7088fef48ab846c2fe0223f8800c 310 SUPERFAMILY SSF52540 4 231 7.68E-63 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16555 4c9c7088fef48ab846c2fe0223f8800c 310 PANTHER PTHR24220 6 302 2.1E-169 T 13-09-2016 THL1_RS16555 4c9c7088fef48ab846c2fe0223f8800c 310 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS16555 4c9c7088fef48ab846c2fe0223f8800c 310 Pfam PF00005 ABC transporter 21 165 2.2E-30 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS10780 7b42b6ed62063ee6461eb57b0c312a19 148 PANTHER PTHR30558:SF5 1 148 8.0E-61 T 13-09-2016 THL1_RS10780 7b42b6ed62063ee6461eb57b0c312a19 148 PANTHER PTHR30558 1 148 8.0E-61 T 13-09-2016 THL1_RS10780 7b42b6ed62063ee6461eb57b0c312a19 148 Pfam PF02472 Biopolymer transport protein ExbD/TolR 12 139 2.1E-25 T 13-09-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 THL1_RS27750 93cba3a8db4f93360433e822c9439c88 140 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 64 134 3.0E-9 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS27750 93cba3a8db4f93360433e822c9439c88 140 PANTHER PTHR40942 1 139 1.4E-43 T 13-09-2016 THL1_RS27750 93cba3a8db4f93360433e822c9439c88 140 SUPERFAMILY SSF46626 60 137 1.59E-12 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS27750 93cba3a8db4f93360433e822c9439c88 140 PANTHER PTHR40942:SF1 1 139 1.4E-43 T 13-09-2016 THL1_RS27750 93cba3a8db4f93360433e822c9439c88 140 PRINTS PR00607 Class IE cytochrome C signature 71 82 2.3E-18 T 13-09-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 THL1_RS27750 93cba3a8db4f93360433e822c9439c88 140 PRINTS PR00607 Class IE cytochrome C signature 82 92 2.3E-18 T 13-09-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 THL1_RS27750 93cba3a8db4f93360433e822c9439c88 140 PRINTS PR00607 Class IE cytochrome C signature 112 124 2.3E-18 T 13-09-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 THL1_RS27750 93cba3a8db4f93360433e822c9439c88 140 PRINTS PR00607 Class IE cytochrome C signature 127 138 2.3E-18 T 13-09-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 THL1_RS27750 93cba3a8db4f93360433e822c9439c88 140 Gene3D G3DSA:1.10.760.10 61 138 4.8E-27 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS04125 608d0efd257d156f15ed03718cd59296 389 TIGRFAM TIGR02326 transamin_PhnW: 2-aminoethylphosphonate--pyruvate transaminase 21 378 3.4E-148 T 13-09-2016 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 THL1_RS04125 608d0efd257d156f15ed03718cd59296 389 Gene3D G3DSA:3.40.640.10 46 267 1.1E-46 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS04125 608d0efd257d156f15ed03718cd59296 389 PIRSF PIRSF000524 15 389 1.4E-53 T 13-09-2016 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 THL1_RS04125 608d0efd257d156f15ed03718cd59296 389 Gene3D G3DSA:3.90.1150.10 268 375 5.9E-42 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS04125 608d0efd257d156f15ed03718cd59296 389 Hamap MF_01376 2-aminoethylphosphonate--pyruvate transaminase [phnW]. 1 385 181.343 T 13-09-2016 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 THL1_RS04125 608d0efd257d156f15ed03718cd59296 389 SUPERFAMILY SSF53383 20 381 1.08E-82 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS04125 608d0efd257d156f15ed03718cd59296 389 TIGRFAM TIGR03301 PhnW-AepZ: 2-aminoethylphosphonate aminotransferase 22 376 2.5E-148 T 13-09-2016 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 THL1_RS04125 608d0efd257d156f15ed03718cd59296 389 PANTHER PTHR21152 19 385 1.2E-124 T 13-09-2016 THL1_RS04125 608d0efd257d156f15ed03718cd59296 389 Pfam PF00266 Aminotransferase class-V 52 307 8.6E-22 T 13-09-2016 IPR000192 Aminotransferase class V domain THL1_RS04125 608d0efd257d156f15ed03718cd59296 389 PANTHER PTHR21152:SF21 19 385 1.2E-124 T 13-09-2016 THL1_RS12570 bfc981ab316ddb90ccf152ed92cd19b5 349 PANTHER PTHR32332 108 348 1.9E-123 T 13-09-2016 THL1_RS12570 bfc981ab316ddb90ccf152ed92cd19b5 349 PANTHER PTHR32332 1 78 1.9E-123 T 13-09-2016 THL1_RS12570 bfc981ab316ddb90ccf152ed92cd19b5 349 Gene3D G3DSA:3.20.20.70 3 339 8.0E-72 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS12570 bfc981ab316ddb90ccf152ed92cd19b5 349 PANTHER PTHR32332:SF12 108 348 1.9E-123 T 13-09-2016 THL1_RS12570 bfc981ab316ddb90ccf152ed92cd19b5 349 PANTHER PTHR32332:SF12 1 78 1.9E-123 T 13-09-2016 THL1_RS12570 bfc981ab316ddb90ccf152ed92cd19b5 349 Pfam PF03060 Nitronate monooxygenase 4 346 1.4E-83 T 13-09-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 THL1_RS12570 bfc981ab316ddb90ccf152ed92cd19b5 349 SUPERFAMILY SSF51412 3 71 3.51E-65 T 13-09-2016 THL1_RS12570 bfc981ab316ddb90ccf152ed92cd19b5 349 SUPERFAMILY SSF51412 101 347 3.51E-65 T 13-09-2016 THL1_RS14010 20f790fa806cc57e06f7ea0cda02b18f 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 9 27 - T 13-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 THL1_RS14010 20f790fa806cc57e06f7ea0cda02b18f 341 SUPERFAMILY SSF47413 6 64 2.81E-18 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS14010 20f790fa806cc57e06f7ea0cda02b18f 341 PANTHER PTHR30146:SF2 6 341 1.4E-103 T 13-09-2016 THL1_RS14010 20f790fa806cc57e06f7ea0cda02b18f 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 1.6E-19 T 13-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 THL1_RS14010 20f790fa806cc57e06f7ea0cda02b18f 341 PANTHER PTHR30146 6 341 1.4E-103 T 13-09-2016 THL1_RS14010 20f790fa806cc57e06f7ea0cda02b18f 341 Gene3D G3DSA:3.40.50.2300 59 179 2.7E-31 T 13-09-2016 THL1_RS14010 20f790fa806cc57e06f7ea0cda02b18f 341 Gene3D G3DSA:1.10.260.40 7 58 1.3E-24 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS14010 20f790fa806cc57e06f7ea0cda02b18f 341 Pfam PF13377 Periplasmic binding protein-like domain 179 337 2.1E-28 T 13-09-2016 THL1_RS14010 20f790fa806cc57e06f7ea0cda02b18f 341 Gene3D G3DSA:3.40.50.2300 180 338 6.7E-37 T 13-09-2016 THL1_RS14010 20f790fa806cc57e06f7ea0cda02b18f 341 SMART SM00354 6 76 1.5E-30 T 13-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 THL1_RS14010 20f790fa806cc57e06f7ea0cda02b18f 341 SUPERFAMILY SSF53822 66 338 3.53E-47 T 13-09-2016 IPR028082 Periplasmic binding protein-like I THL1_RS02615 15a453a2f17dc0e4e5f4e5f0577d59ee 432 Pfam PF13616 PPIC-type PPIASE domain 287 387 1.7E-27 T 13-09-2016 THL1_RS02615 15a453a2f17dc0e4e5f4e5f0577d59ee 432 Gene3D G3DSA:3.10.50.40 289 409 9.7E-36 T 13-09-2016 THL1_RS02615 15a453a2f17dc0e4e5f4e5f0577d59ee 432 Gene3D G3DSA:3.10.50.40 175 286 7.7E-31 T 13-09-2016 THL1_RS02615 15a453a2f17dc0e4e5f4e5f0577d59ee 432 SUPERFAMILY SSF54534 179 284 3.27E-28 T 13-09-2016 THL1_RS02615 15a453a2f17dc0e4e5f4e5f0577d59ee 432 SUPERFAMILY SSF54534 288 389 3.86E-32 T 13-09-2016 THL1_RS02615 15a453a2f17dc0e4e5f4e5f0577d59ee 432 Pfam PF09312 SurA N-terminal domain 32 149 1.3E-47 T 13-09-2016 IPR015391 SurA N-terminal THL1_RS02615 15a453a2f17dc0e4e5f4e5f0577d59ee 432 Hamap MF_01183 Chaperone SurA [surA]. 14 432 33.109 T 13-09-2016 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0042710|GO:0043165|GO:0050821|GO:0051082|GO:0051085|GO:0060274 THL1_RS02615 15a453a2f17dc0e4e5f4e5f0577d59ee 432 Gene3D G3DSA:1.10.3120.10 44 122 4.5E-4 T 13-09-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 THL1_RS02615 15a453a2f17dc0e4e5f4e5f0577d59ee 432 Pfam PF00639 PPIC-type PPIASE domain 186 277 2.3E-19 T 13-09-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 THL1_RS02615 15a453a2f17dc0e4e5f4e5f0577d59ee 432 PANTHER PTHR10657 14 429 1.3E-230 T 13-09-2016 THL1_RS02615 15a453a2f17dc0e4e5f4e5f0577d59ee 432 SUPERFAMILY SSF109998 32 208 3.73E-44 T 13-09-2016 IPR027304 Trigger factor/SurA domain THL1_RS02615 15a453a2f17dc0e4e5f4e5f0577d59ee 432 PANTHER PTHR10657:SF16 14 429 1.3E-230 T 13-09-2016 THL1_RS27285 2384aab044e19e4c5c5071a5fec4277d 614 SMART SM01079 75 218 3.9E-20 T 13-09-2016 IPR006189 CHASE domain THL1_RS27285 2384aab044e19e4c5c5071a5fec4277d 614 PANTHER PTHR10799 38 113 8.0E-31 T 13-09-2016 THL1_RS27285 2384aab044e19e4c5c5071a5fec4277d 614 PANTHER PTHR10799:SF750 38 113 8.0E-31 T 13-09-2016 THL1_RS27285 2384aab044e19e4c5c5071a5fec4277d 614 Gene3D G3DSA:3.30.70.270 447 611 7.6E-57 T 13-09-2016 THL1_RS27285 2384aab044e19e4c5c5071a5fec4277d 614 SMART SM00267 434 609 1.4E-68 T 13-09-2016 IPR000160 GGDEF domain THL1_RS27285 2384aab044e19e4c5c5071a5fec4277d 614 Gene3D G3DSA:3.30.450.20 304 430 5.8E-13 T 13-09-2016 THL1_RS27285 2384aab044e19e4c5c5071a5fec4277d 614 Pfam PF03924 CHASE domain 111 198 1.1E-14 T 13-09-2016 IPR006189 CHASE domain THL1_RS27285 2384aab044e19e4c5c5071a5fec4277d 614 Pfam PF13188 PAS domain 317 383 2.5E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS27285 2384aab044e19e4c5c5071a5fec4277d 614 PANTHER PTHR10799:SF750 478 613 8.0E-31 T 13-09-2016 THL1_RS27285 2384aab044e19e4c5c5071a5fec4277d 614 PANTHER PTHR10799 478 613 8.0E-31 T 13-09-2016 THL1_RS27285 2384aab044e19e4c5c5071a5fec4277d 614 Pfam PF00990 Diguanylate cyclase, GGDEF domain 446 605 2.8E-51 T 13-09-2016 IPR000160 GGDEF domain THL1_RS27285 2384aab044e19e4c5c5071a5fec4277d 614 SUPERFAMILY SSF55073 450 611 4.47E-49 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS27285 2384aab044e19e4c5c5071a5fec4277d 614 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 441 607 2.1E-53 T 13-09-2016 IPR000160 GGDEF domain THL1_RS27285 2384aab044e19e4c5c5071a5fec4277d 614 SUPERFAMILY SSF55785 303 430 2.47E-12 T 13-09-2016 IPR000014 PAS domain THL1_RS19925 e524102a072d1abd46a9781f75d78b60 223 Pfam PF10294 Lysine methyltransferase 50 177 5.1E-12 T 13-09-2016 IPR019410 Lysine methyltransferase THL1_RS19925 e524102a072d1abd46a9781f75d78b60 223 SUPERFAMILY SSF53335 17 189 3.58E-18 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS19925 e524102a072d1abd46a9781f75d78b60 223 PANTHER PTHR14614 51 188 2.6E-22 T 13-09-2016 THL1_RS19925 e524102a072d1abd46a9781f75d78b60 223 Gene3D G3DSA:3.40.50.150 28 191 2.2E-33 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS23295 b9714ec53c09adf8fc53e62dc1301c39 256 PANTHER PTHR30136 4 256 7.9E-47 T 13-09-2016 THL1_RS23295 b9714ec53c09adf8fc53e62dc1301c39 256 SUPERFAMILY SSF55781 84 256 2.68E-20 T 13-09-2016 IPR029016 GAF domain-like THL1_RS23295 b9714ec53c09adf8fc53e62dc1301c39 256 Gene3D G3DSA:1.10.10.10 4 69 9.7E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS23295 b9714ec53c09adf8fc53e62dc1301c39 256 PANTHER PTHR30136:SF3 4 256 7.9E-47 T 13-09-2016 THL1_RS23295 b9714ec53c09adf8fc53e62dc1301c39 256 Pfam PF09339 IclR helix-turn-helix domain 12 60 8.4E-14 T 13-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 THL1_RS23295 b9714ec53c09adf8fc53e62dc1301c39 256 SUPERFAMILY SSF46785 10 72 2.03E-10 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS23295 b9714ec53c09adf8fc53e62dc1301c39 256 SMART SM00346 10 99 1.5E-10 T 13-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 THL1_RS23295 b9714ec53c09adf8fc53e62dc1301c39 256 Gene3D G3DSA:3.30.450.40 84 256 5.0E-21 T 13-09-2016 IPR029016 GAF domain-like THL1_RS05605 8b20a6a69794e698657b897b04cc025a 97 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 13 95 3.3E-24 T 13-09-2016 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 THL1_RS05605 8b20a6a69794e698657b897b04cc025a 97 PANTHER PTHR37479:SF1 1 97 3.2E-34 T 13-09-2016 THL1_RS05605 8b20a6a69794e698657b897b04cc025a 97 PANTHER PTHR37479 1 97 3.2E-34 T 13-09-2016 THL1_RS05605 8b20a6a69794e698657b897b04cc025a 97 Hamap MF_00910 Cell division protein FtsL [ftsL]. 12 95 15.024 T 13-09-2016 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 THL1_RS05605 8b20a6a69794e698657b897b04cc025a 97 Pfam PF04999 Cell division protein FtsL 1 96 3.9E-31 T 13-09-2016 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 THL1_RS07890 cfee1913818e137acba49a964dd92752 145 Gene3D G3DSA:3.30.70.920 78 144 5.3E-15 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS07890 cfee1913818e137acba49a964dd92752 145 SMART SM00344 5 113 1.8E-21 T 13-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 THL1_RS07890 cfee1913818e137acba49a964dd92752 145 SUPERFAMILY SSF46785 4 57 2.11E-13 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07890 cfee1913818e137acba49a964dd92752 145 Pfam PF13404 AsnC-type helix-turn-helix domain 5 46 1.3E-13 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS07890 cfee1913818e137acba49a964dd92752 145 Pfam PF01037 Lrp/AsnC ligand binding domain 83 142 4.1E-15 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS07890 cfee1913818e137acba49a964dd92752 145 Gene3D G3DSA:1.10.10.10 5 55 2.4E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07890 cfee1913818e137acba49a964dd92752 145 SUPERFAMILY SSF54909 69 144 3.89E-14 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS07890 cfee1913818e137acba49a964dd92752 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 1.5E-12 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS07890 cfee1913818e137acba49a964dd92752 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.5E-12 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS07890 cfee1913818e137acba49a964dd92752 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.5E-12 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS07890 cfee1913818e137acba49a964dd92752 145 ProSitePatterns PS00519 AsnC-type HTH domain signature. 23 49 - T 13-09-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site THL1_RS07890 cfee1913818e137acba49a964dd92752 145 PANTHER PTHR30154 1 145 1.9E-31 T 13-09-2016 THL1_RS05560 6a24131edbc195491524b44ef9da9245 142 PANTHER PTHR37486 1 142 5.2E-72 T 13-09-2016 THL1_RS05560 6a24131edbc195491524b44ef9da9245 142 SUPERFAMILY SSF101738 1 114 9.29E-48 T 13-09-2016 IPR007481 Stringent starvation protein B THL1_RS05560 6a24131edbc195491524b44ef9da9245 142 PIRSF PIRSF005276 1 142 1.7E-56 T 13-09-2016 IPR007481 Stringent starvation protein B THL1_RS05560 6a24131edbc195491524b44ef9da9245 142 Pfam PF04386 Stringent starvation protein B 4 142 1.7E-35 T 13-09-2016 IPR007481 Stringent starvation protein B THL1_RS05560 6a24131edbc195491524b44ef9da9245 142 Gene3D G3DSA:2.30.30.220 1 103 2.2E-48 T 13-09-2016 IPR007481 Stringent starvation protein B THL1_RS05560 6a24131edbc195491524b44ef9da9245 142 PANTHER PTHR37486:SF1 1 142 5.2E-72 T 13-09-2016 THL1_RS10790 5ad309aec3cb4d219cf53a6a4f0d8661 61 Pfam PF03966 Trm112p-like protein 2 41 1.3E-10 T 13-09-2016 IPR005651 Uncharacterised protein family UPF0434/Trm112 THL1_RS10790 5ad309aec3cb4d219cf53a6a4f0d8661 61 Gene3D G3DSA:2.20.25.10 8 58 1.2E-24 T 13-09-2016 THL1_RS10790 5ad309aec3cb4d219cf53a6a4f0d8661 61 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 26.395 T 13-09-2016 IPR005651 Uncharacterised protein family UPF0434/Trm112 THL1_RS10790 5ad309aec3cb4d219cf53a6a4f0d8661 61 SUPERFAMILY SSF158997 1 54 7.19E-20 T 13-09-2016 THL1_RS10790 5ad309aec3cb4d219cf53a6a4f0d8661 61 PANTHER PTHR33505 1 58 1.8E-23 T 13-09-2016 THL1_RS06885 a7c5cc844f85154f4d54fa5b0aa69ec6 76 Hamap MF_00690 UPF0270 protein YheU [yheU]. 1 69 22.814 T 13-09-2016 IPR010648 Uncharacterised protein family UPF0270 THL1_RS06885 a7c5cc844f85154f4d54fa5b0aa69ec6 76 Gene3D G3DSA:1.10.10.610 1 73 1.5E-28 T 13-09-2016 IPR010648 Uncharacterised protein family UPF0270 THL1_RS06885 a7c5cc844f85154f4d54fa5b0aa69ec6 76 Pfam PF06794 Uncharacterised protein family (UPF0270) 1 66 4.9E-26 T 13-09-2016 IPR010648 Uncharacterised protein family UPF0270 THL1_RS06885 a7c5cc844f85154f4d54fa5b0aa69ec6 76 PIRSF PIRSF006169 1 75 4.9E-29 T 13-09-2016 IPR010648 Uncharacterised protein family UPF0270 THL1_RS06885 a7c5cc844f85154f4d54fa5b0aa69ec6 76 SUPERFAMILY SSF118001 1 74 3.4E-26 T 13-09-2016 IPR010648 Uncharacterised protein family UPF0270 THL1_RS06885 a7c5cc844f85154f4d54fa5b0aa69ec6 76 ProDom PD026997 UPF0270 YHEU SO0879 3D-STRUCTURE LYASE PLU0398 YPO0179/Y3960/YP0178 ENOLASE HD0737 PSPTO1630 1 66 4.0E-25 T 13-09-2016 IPR010648 Uncharacterised protein family UPF0270 THL1_RS25600 3af1707d5a69305decb1c88d86c90959 288 PANTHER PTHR21631:SF19 10 288 4.1E-161 T 13-09-2016 THL1_RS25600 3af1707d5a69305decb1c88d86c90959 288 PANTHER PTHR21631 10 288 4.1E-161 T 13-09-2016 THL1_RS25600 3af1707d5a69305decb1c88d86c90959 288 Gene3D G3DSA:3.20.20.60 8 257 8.2E-64 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS25600 3af1707d5a69305decb1c88d86c90959 288 Hamap MF_01299 Oxaloacetate decarboxylase. 4 288 46.221 T 13-09-2016 IPR023687 Oxaloacetate decarboxylase, bacterial GO:0008948 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 THL1_RS25600 3af1707d5a69305decb1c88d86c90959 288 Pfam PF13714 Phosphoenolpyruvate phosphomutase 13 247 5.2E-46 T 13-09-2016 THL1_RS25600 3af1707d5a69305decb1c88d86c90959 288 SUPERFAMILY SSF51621 8 271 7.18E-70 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS00265 7caa98324b7c243c088f8461598836e9 295 Pfam PF00510 Cytochrome c oxidase subunit III 155 294 2.3E-43 T 13-09-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 THL1_RS00265 7caa98324b7c243c088f8461598836e9 295 Pfam PF00510 Cytochrome c oxidase subunit III 7 109 1.0E-10 T 13-09-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 THL1_RS00265 7caa98324b7c243c088f8461598836e9 295 Gene3D G3DSA:1.10.287.70 2 74 5.6E-19 T 13-09-2016 THL1_RS00265 7caa98324b7c243c088f8461598836e9 295 Gene3D G3DSA:1.20.120.80 79 294 6.3E-69 T 13-09-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 THL1_RS00265 7caa98324b7c243c088f8461598836e9 295 SUPERFAMILY SSF81452 3 295 1.83E-85 T 13-09-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 THL1_RS00265 7caa98324b7c243c088f8461598836e9 295 PANTHER PTHR11403 1 120 3.5E-120 T 13-09-2016 IPR024791 Cytochrome c oxidase subunit III GO:0015002|GO:0016020|GO:0019646 THL1_RS00265 7caa98324b7c243c088f8461598836e9 295 PANTHER PTHR11403 150 295 3.5E-120 T 13-09-2016 IPR024791 Cytochrome c oxidase subunit III GO:0015002|GO:0016020|GO:0019646 THL1_RS00265 7caa98324b7c243c088f8461598836e9 295 PANTHER PTHR11403:SF0 1 120 3.5E-120 T 13-09-2016 THL1_RS00265 7caa98324b7c243c088f8461598836e9 295 PANTHER PTHR11403:SF0 150 295 3.5E-120 T 13-09-2016 THL1_RS01055 e19aa3dc3f7253373908b6bce366d25e 1366 Gene3D G3DSA:3.40.50.300 905 1076 4.3E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01055 e19aa3dc3f7253373908b6bce366d25e 1366 SMART SM00490 1226 1308 2.5E-23 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS01055 e19aa3dc3f7253373908b6bce366d25e 1366 Gene3D G3DSA:3.40.50.300 1196 1342 7.0E-24 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01055 e19aa3dc3f7253373908b6bce366d25e 1366 PANTHER PTHR10799 905 1362 2.1E-168 T 13-09-2016 THL1_RS01055 e19aa3dc3f7253373908b6bce366d25e 1366 Pfam PF00176 SNF2 family N-terminal domain 933 1186 6.4E-52 T 13-09-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 THL1_RS01055 e19aa3dc3f7253373908b6bce366d25e 1366 SUPERFAMILY SSF52540 902 1117 2.26E-50 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01055 e19aa3dc3f7253373908b6bce366d25e 1366 Pfam PF00271 Helicase conserved C-terminal domain 1197 1308 2.5E-20 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS01055 e19aa3dc3f7253373908b6bce366d25e 1366 SMART SM00487 910 1090 2.2E-21 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS01055 e19aa3dc3f7253373908b6bce366d25e 1366 SUPERFAMILY SSF52540 1119 1349 5.88E-65 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24505 a8bb6cae4b3385492e5112ab5ea40971 134 PANTHER PTHR33202 5 129 2.3E-40 T 13-09-2016 THL1_RS24505 a8bb6cae4b3385492e5112ab5ea40971 134 Pfam PF01475 Ferric uptake regulator family 9 129 2.2E-45 T 13-09-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 THL1_RS24505 a8bb6cae4b3385492e5112ab5ea40971 134 SUPERFAMILY SSF46785 5 131 4.21E-41 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS24505 a8bb6cae4b3385492e5112ab5ea40971 134 Gene3D G3DSA:1.10.10.10 5 81 1.6E-30 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 ProDom PD485437 REGULATOR TRANSCRIPTIONAL FIS-TYPE HELIX-TURN-HELIX ACTIVATOR PLASMID FAMILY PHENOL-DEGRADATIVE FIS SIGMA-54 65 172 2.0E-57 T 13-09-2016 IPR010523 Activator of aromatic catabolism THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 288 301 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 Gene3D G3DSA:1.10.10.60 566 607 9.3E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 Pfam PF02830 V4R domain 158 219 1.3E-15 T 13-09-2016 IPR004096 4-vinyl reductase, 4VR THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 477 486 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 Gene3D G3DSA:1.10.8.60 437 506 1.2E-21 T 13-09-2016 THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 SMART SM00989 157 219 1.2E-25 T 13-09-2016 IPR004096 4-vinyl reductase, 4VR THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 Pfam PF02954 Bacterial regulatory protein, Fis family 568 607 4.2E-12 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 575 592 6.2E-9 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 592 609 6.2E-9 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 Pfam PF00158 Sigma-54 interaction domain 265 431 2.2E-67 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 PANTHER PTHR32071 532 607 7.5E-141 T 13-09-2016 THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 PANTHER PTHR32071 249 513 7.5E-141 T 13-09-2016 THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 Gene3D G3DSA:3.40.50.300 261 436 1.2E-57 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 Pfam PF06505 Activator of aromatic catabolism 47 146 4.0E-35 T 13-09-2016 IPR010523 Activator of aromatic catabolism THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 SUPERFAMILY SSF111126 73 214 2.14E-12 T 13-09-2016 IPR024096 NO signalling/Golgi transport ligand-binding domain THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 SUPERFAMILY SSF52540 264 499 1.73E-71 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 SUPERFAMILY SSF46689 478 512 3.0E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 SUPERFAMILY SSF46689 559 607 3.0E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 Gene3D G3DSA:3.30.1380.20 53 223 1.2E-18 T 13-09-2016 THL1_RS03215 21e4f7988d0859350265054191b1b09a 609 SMART SM00382 284 428 1.9E-13 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS09775 aa6ce68aa5dcdb505da8f5ebe50b1fc3 142 PANTHER PTHR11803 27 139 2.1E-34 T 13-09-2016 IPR006175 YjgF/YER057c/UK114 family THL1_RS09775 aa6ce68aa5dcdb505da8f5ebe50b1fc3 142 Gene3D G3DSA:3.30.1330.40 5 141 2.4E-40 T 13-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THL1_RS09775 aa6ce68aa5dcdb505da8f5ebe50b1fc3 142 Pfam PF01042 Endoribonuclease L-PSP 26 133 3.1E-22 T 13-09-2016 IPR006175 YjgF/YER057c/UK114 family THL1_RS09775 aa6ce68aa5dcdb505da8f5ebe50b1fc3 142 SUPERFAMILY SSF55298 25 139 6.6E-32 T 13-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THL1_RS27250 6823e1613ce81476f0a359b6d9ce20a2 444 Pfam PF05195 Aminopeptidase P, N-terminal domain 9 128 2.2E-37 T 13-09-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 THL1_RS27250 6823e1613ce81476f0a359b6d9ce20a2 444 SUPERFAMILY SSF55920 177 437 1.83E-85 T 13-09-2016 IPR000994 Peptidase M24, structural domain THL1_RS27250 6823e1613ce81476f0a359b6d9ce20a2 444 Gene3D G3DSA:3.90.230.10 181 437 2.2E-87 T 13-09-2016 IPR000994 Peptidase M24, structural domain THL1_RS27250 6823e1613ce81476f0a359b6d9ce20a2 444 Gene3D G3DSA:3.40.350.10 4 180 8.9E-57 T 13-09-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal THL1_RS27250 6823e1613ce81476f0a359b6d9ce20a2 444 PANTHER PTHR10804:SF17 3 437 2.6E-168 T 13-09-2016 THL1_RS27250 6823e1613ce81476f0a359b6d9ce20a2 444 Pfam PF00557 Metallopeptidase family M24 184 415 5.0E-64 T 13-09-2016 IPR000994 Peptidase M24, structural domain THL1_RS27250 6823e1613ce81476f0a359b6d9ce20a2 444 SMART SM01011 4 138 1.3E-70 T 13-09-2016 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 THL1_RS27250 6823e1613ce81476f0a359b6d9ce20a2 444 PANTHER PTHR10804 3 437 2.6E-168 T 13-09-2016 THL1_RS27250 6823e1613ce81476f0a359b6d9ce20a2 444 SUPERFAMILY SSF53092 4 176 8.72E-58 T 13-09-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal THL1_RS05080 df0547d5506d43af3b12ac387582f8f0 568 PANTHER PTHR30258 1 567 1.4E-263 T 13-09-2016 THL1_RS05080 df0547d5506d43af3b12ac387582f8f0 568 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 387 401 - T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS05080 df0547d5506d43af3b12ac387582f8f0 568 SUPERFAMILY SSF52540 182 566 7.83E-97 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05080 df0547d5506d43af3b12ac387582f8f0 568 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 44 148 7.2E-19 T 13-09-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 THL1_RS05080 df0547d5506d43af3b12ac387582f8f0 568 Gene3D G3DSA:3.30.450.90 169 292 6.4E-50 T 13-09-2016 THL1_RS05080 df0547d5506d43af3b12ac387582f8f0 568 PANTHER PTHR30258:SF1 1 567 1.4E-263 T 13-09-2016 THL1_RS05080 df0547d5506d43af3b12ac387582f8f0 568 TIGRFAM TIGR02538 type_IV_pilB: type IV-A pilus assembly ATPase PilB 10 568 1.5E-259 T 13-09-2016 IPR013374 ATPase, type IV, pilus assembly, PilB GO:0005524|GO:0008565|GO:0009297 THL1_RS05080 df0547d5506d43af3b12ac387582f8f0 568 Gene3D G3DSA:3.40.50.300 300 567 4.4E-96 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05080 df0547d5506d43af3b12ac387582f8f0 568 Pfam PF00437 Type II/IV secretion system protein 192 459 2.5E-88 T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS05080 df0547d5506d43af3b12ac387582f8f0 568 SUPERFAMILY SSF160246 6 145 7.59E-37 T 13-09-2016 THL1_RS10805 e2c6b75a04435820c9ceaa3fc0ac09b5 339 Gene3D G3DSA:3.30.43.10 10 73 1.4E-22 T 13-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 THL1_RS10805 e2c6b75a04435820c9ceaa3fc0ac09b5 339 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 339 86.871 T 13-09-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS10805 e2c6b75a04435820c9ceaa3fc0ac09b5 339 Pfam PF01565 FAD binding domain 24 156 8.8E-26 T 13-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THL1_RS10805 e2c6b75a04435820c9ceaa3fc0ac09b5 339 Gene3D G3DSA:3.30.465.10 81 238 1.7E-51 T 13-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THL1_RS10805 e2c6b75a04435820c9ceaa3fc0ac09b5 339 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 11 337 1.5E-67 T 13-09-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS10805 e2c6b75a04435820c9ceaa3fc0ac09b5 339 PANTHER PTHR21071:SF6 5 339 1.9E-155 T 13-09-2016 THL1_RS10805 e2c6b75a04435820c9ceaa3fc0ac09b5 339 SUPERFAMILY SSF56176 10 197 8.88E-44 T 13-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THL1_RS10805 e2c6b75a04435820c9ceaa3fc0ac09b5 339 PANTHER PTHR21071 5 339 1.9E-155 T 13-09-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS10805 e2c6b75a04435820c9ceaa3fc0ac09b5 339 SUPERFAMILY SSF56194 212 339 3.27E-46 T 13-09-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS10805 e2c6b75a04435820c9ceaa3fc0ac09b5 339 Gene3D G3DSA:3.90.78.10 239 339 2.3E-39 T 13-09-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS10805 e2c6b75a04435820c9ceaa3fc0ac09b5 339 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 216 339 3.5E-32 T 13-09-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS24390 b3a7872c7aed999791571531d992a3e2 129 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 100 2.0E-38 T 13-09-2016 IPR000238 Ribosome-binding factor A GO:0006364 THL1_RS24390 b3a7872c7aed999791571531d992a3e2 129 Pfam PF02033 Ribosome-binding factor A 7 113 1.2E-31 T 13-09-2016 IPR000238 Ribosome-binding factor A GO:0006364 THL1_RS24390 b3a7872c7aed999791571531d992a3e2 129 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 120 22.886 T 13-09-2016 IPR000238 Ribosome-binding factor A GO:0006364 THL1_RS24390 b3a7872c7aed999791571531d992a3e2 129 Gene3D G3DSA:3.30.300.20 4 120 1.1E-39 T 13-09-2016 IPR015946 K homology domain-like, alpha/beta THL1_RS24390 b3a7872c7aed999791571531d992a3e2 129 PANTHER PTHR33515 1 122 3.8E-45 T 13-09-2016 THL1_RS24390 b3a7872c7aed999791571531d992a3e2 129 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 115 8.1E-34 T 13-09-2016 IPR000238 Ribosome-binding factor A GO:0006364 THL1_RS24390 b3a7872c7aed999791571531d992a3e2 129 ProSitePatterns PS01319 Ribosome-binding factor A signature. 79 100 - T 13-09-2016 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 THL1_RS24390 b3a7872c7aed999791571531d992a3e2 129 SUPERFAMILY SSF89919 2 107 1.2E-33 T 13-09-2016 IPR023799 Ribosome-binding factor A domain THL1_RS24915 808f99918127a0f795e2d6a713c25b6e 264 PANTHER PTHR35811 12 233 1.7E-58 T 13-09-2016 THL1_RS24915 808f99918127a0f795e2d6a713c25b6e 264 Gene3D G3DSA:3.40.50.1010 6 148 1.1E-29 T 13-09-2016 IPR029060 PIN domain-like THL1_RS24915 808f99918127a0f795e2d6a713c25b6e 264 Pfam PF01936 NYN domain 14 146 5.2E-32 T 13-09-2016 IPR021139 NYN domain, limkain-b1-type THL1_RS24915 808f99918127a0f795e2d6a713c25b6e 264 PANTHER PTHR35811:SF1 12 233 1.7E-58 T 13-09-2016 THL1_RS24915 808f99918127a0f795e2d6a713c25b6e 264 Pfam PF12872 OST-HTH/LOTUS domain 187 248 7.1E-15 T 13-09-2016 IPR025605 OST-HTH/LOTUS domain THL1_RS20090 d1cf892a93c0f2305a41ad2c8389a302 304 Gene3D G3DSA:3.40.50.2300 143 263 1.0E-14 T 13-09-2016 THL1_RS20090 d1cf892a93c0f2305a41ad2c8389a302 304 Gene3D G3DSA:3.40.50.2300 5 126 1.0E-29 T 13-09-2016 THL1_RS20090 d1cf892a93c0f2305a41ad2c8389a302 304 PANTHER PTHR26402 5 121 1.7E-45 T 13-09-2016 THL1_RS20090 d1cf892a93c0f2305a41ad2c8389a302 304 PANTHER PTHR26402:SF509 5 121 1.7E-45 T 13-09-2016 THL1_RS20090 d1cf892a93c0f2305a41ad2c8389a302 304 SMART SM00448 5 116 2.2E-21 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS20090 d1cf892a93c0f2305a41ad2c8389a302 304 SMART SM00448 142 254 0.012 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS20090 d1cf892a93c0f2305a41ad2c8389a302 304 Pfam PF00072 Response regulator receiver domain 145 248 1.4E-7 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS20090 d1cf892a93c0f2305a41ad2c8389a302 304 Pfam PF00072 Response regulator receiver domain 7 113 3.5E-18 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS20090 d1cf892a93c0f2305a41ad2c8389a302 304 SUPERFAMILY SSF52172 141 266 1.71E-16 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS20090 d1cf892a93c0f2305a41ad2c8389a302 304 SUPERFAMILY SSF52172 4 125 1.05E-29 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS00060 0cd01ebd631f0815259742c35c5f709c 681 Gene3D G3DSA:1.10.730.10 577 668 9.2E-4 T 13-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS00060 0cd01ebd631f0815259742c35c5f709c 681 SMART SM00836 580 680 8.9E-4 T 13-09-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 THL1_RS00060 0cd01ebd631f0815259742c35c5f709c 681 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 3 680 25.386 T 13-09-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THL1_RS00060 0cd01ebd631f0815259742c35c5f709c 681 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 1 680 4.7E-238 T 13-09-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THL1_RS00060 0cd01ebd631f0815259742c35c5f709c 681 PANTHER PTHR30075 1 681 0.0 T 13-09-2016 THL1_RS00060 0cd01ebd631f0815259742c35c5f709c 681 SUPERFAMILY SSF109604 334 485 5.89E-19 T 13-09-2016 THL1_RS00060 0cd01ebd631f0815259742c35c5f709c 681 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 50 62 1.6E-35 T 13-09-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THL1_RS00060 0cd01ebd631f0815259742c35c5f709c 681 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 389 408 1.6E-35 T 13-09-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THL1_RS00060 0cd01ebd631f0815259742c35c5f709c 681 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 241 256 1.6E-35 T 13-09-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THL1_RS00060 0cd01ebd631f0815259742c35c5f709c 681 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 313 329 1.6E-35 T 13-09-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THL1_RS00060 0cd01ebd631f0815259742c35c5f709c 681 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 7 20 1.6E-35 T 13-09-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THL1_RS00060 0cd01ebd631f0815259742c35c5f709c 681 Pfam PF05746 DALR anticodon binding domain 577 668 2.2E-6 T 13-09-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 THL1_RS00060 0cd01ebd631f0815259742c35c5f709c 681 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 6 544 3.4E-204 T 13-09-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THL1_RS27890 f6020032ce03b6b34bfd6bb269ae1f42 702 Pfam PF04607 Region found in RelA / SpoT proteins 235 345 3.2E-37 T 13-09-2016 IPR007685 RelA/SpoT GO:0015969 THL1_RS27890 f6020032ce03b6b34bfd6bb269ae1f42 702 SUPERFAMILY SSF109604 4 191 4.71E-70 T 13-09-2016 THL1_RS27890 f6020032ce03b6b34bfd6bb269ae1f42 702 Gene3D G3DSA:3.30.70.260 625 697 5.2E-8 T 13-09-2016 THL1_RS27890 f6020032ce03b6b34bfd6bb269ae1f42 702 SUPERFAMILY SSF55021 626 700 1.63E-7 T 13-09-2016 THL1_RS27890 f6020032ce03b6b34bfd6bb269ae1f42 702 Pfam PF13291 ACT domain 623 699 5.5E-16 T 13-09-2016 IPR002912 ACT domain GO:0008152|GO:0016597 THL1_RS27890 f6020032ce03b6b34bfd6bb269ae1f42 702 PANTHER PTHR21262:SF0 2 702 0.0 T 13-09-2016 THL1_RS27890 f6020032ce03b6b34bfd6bb269ae1f42 702 SMART SM00471 41 153 6.4E-8 T 13-09-2016 IPR003607 HD/PDEase domain THL1_RS27890 f6020032ce03b6b34bfd6bb269ae1f42 702 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 26 698 3.3E-242 T 13-09-2016 IPR004811 RelA/SpoT family GO:0015969 THL1_RS27890 f6020032ce03b6b34bfd6bb269ae1f42 702 SUPERFAMILY SSF81271 376 448 1.63E-22 T 13-09-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 THL1_RS27890 f6020032ce03b6b34bfd6bb269ae1f42 702 Pfam PF02824 TGS domain 389 448 4.1E-19 T 13-09-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 THL1_RS27890 f6020032ce03b6b34bfd6bb269ae1f42 702 PANTHER PTHR21262 2 702 0.0 T 13-09-2016 THL1_RS27890 f6020032ce03b6b34bfd6bb269ae1f42 702 SMART SM00954 235 345 7.6E-65 T 13-09-2016 IPR007685 RelA/SpoT GO:0015969 THL1_RS27890 f6020032ce03b6b34bfd6bb269ae1f42 702 Pfam PF13328 HD domain 26 175 6.0E-51 T 13-09-2016 IPR003607 HD/PDEase domain THL1_RS27890 f6020032ce03b6b34bfd6bb269ae1f42 702 Gene3D G3DSA:3.30.460.10 178 325 1.9E-46 T 13-09-2016 THL1_RS27890 f6020032ce03b6b34bfd6bb269ae1f42 702 Gene3D G3DSA:3.10.20.30 388 449 1.4E-21 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS27890 f6020032ce03b6b34bfd6bb269ae1f42 702 SUPERFAMILY SSF81301 181 393 6.7E-61 T 13-09-2016 THL1_RS17495 5e6faede670d54224e0b3c7a7f5518f8 403 PANTHER PTHR30483 1 402 3.1E-183 T 13-09-2016 THL1_RS17495 5e6faede670d54224e0b3c7a7f5518f8 403 Pfam PF13458 Periplasmic binding protein 28 365 7.6E-82 T 13-09-2016 IPR028081 Leucine-binding protein domain THL1_RS17495 5e6faede670d54224e0b3c7a7f5518f8 403 PANTHER PTHR30483:SF17 1 402 3.1E-183 T 13-09-2016 THL1_RS17495 5e6faede670d54224e0b3c7a7f5518f8 403 Gene3D G3DSA:3.40.50.2300 28 223 2.0E-38 T 13-09-2016 THL1_RS17495 5e6faede670d54224e0b3c7a7f5518f8 403 SUPERFAMILY SSF53822 28 400 2.22E-85 T 13-09-2016 IPR028082 Periplasmic binding protein-like I THL1_RS12155 80573388ecda6d36dc89a3c28379779c 293 PANTHER PTHR11079 16 293 3.9E-99 T 13-09-2016 THL1_RS12155 80573388ecda6d36dc89a3c28379779c 293 SUPERFAMILY SSF55120 75 290 4.32E-49 T 13-09-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS12155 80573388ecda6d36dc89a3c28379779c 293 Pfam PF00849 RNA pseudouridylate synthase 91 238 2.5E-25 T 13-09-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS12155 80573388ecda6d36dc89a3c28379779c 293 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 130 144 - T 13-09-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS12155 80573388ecda6d36dc89a3c28379779c 293 PANTHER PTHR11079:SF61 16 293 3.9E-99 T 13-09-2016 THL1_RS00445 0036fc2e35a13ffbad77570a436b9399 1081 PIRSF PIRSF000980 1 1081 0.0 T 13-09-2016 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 THL1_RS00445 0036fc2e35a13ffbad77570a436b9399 1081 SUPERFAMILY SSF52980 779 1074 2.25E-60 T 13-09-2016 IPR011335 Restriction endonuclease type II-like THL1_RS00445 0036fc2e35a13ffbad77570a436b9399 1081 PANTHER PTHR30591:SF1 1 1081 8.3E-224 T 13-09-2016 THL1_RS00445 0036fc2e35a13ffbad77570a436b9399 1081 SUPERFAMILY SSF52540 1 315 1.02E-90 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00445 0036fc2e35a13ffbad77570a436b9399 1081 Gene3D G3DSA:3.40.50.300 302 413 1.5E-6 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00445 0036fc2e35a13ffbad77570a436b9399 1081 Gene3D G3DSA:3.40.50.300 619 714 1.5E-6 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00445 0036fc2e35a13ffbad77570a436b9399 1081 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 2 1032 2.3E-286 T 13-09-2016 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 THL1_RS00445 0036fc2e35a13ffbad77570a436b9399 1081 PANTHER PTHR30591 1 1081 8.3E-224 T 13-09-2016 THL1_RS00445 0036fc2e35a13ffbad77570a436b9399 1081 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 1 1076 12.755 T 13-09-2016 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 THL1_RS00445 0036fc2e35a13ffbad77570a436b9399 1081 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 1 755 4.6E-260 T 13-09-2016 THL1_RS00445 0036fc2e35a13ffbad77570a436b9399 1081 SUPERFAMILY SSF52540 323 766 1.91E-89 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00445 0036fc2e35a13ffbad77570a436b9399 1081 Gene3D G3DSA:1.10.10.160 86 174 1.3E-22 T 13-09-2016 IPR013986 DExx box DNA helicase domain THL1_RS01165 33b2851c7442ffbe77ee034806079e67 476 Gene3D G3DSA:3.40.605.10 13 239 3.3E-57 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS01165 33b2851c7442ffbe77ee034806079e67 476 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 224 231 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS01165 33b2851c7442ffbe77ee034806079e67 476 Pfam PF00171 Aldehyde dehydrogenase family 14 445 1.6E-89 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS01165 33b2851c7442ffbe77ee034806079e67 476 PANTHER PTHR11699 12 476 1.3E-189 T 13-09-2016 THL1_RS01165 33b2851c7442ffbe77ee034806079e67 476 SUPERFAMILY SSF53720 14 472 1.44E-121 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS01165 33b2851c7442ffbe77ee034806079e67 476 Gene3D G3DSA:3.40.309.10 240 426 8.0E-52 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS01165 33b2851c7442ffbe77ee034806079e67 476 PIRSF PIRSF036492 6 476 4.9E-168 T 13-09-2016 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 THL1_RS01165 33b2851c7442ffbe77ee034806079e67 476 PANTHER PTHR11699:SF15 12 476 1.3E-189 T 13-09-2016 THL1_RS10580 52f8a7672cf87320c252f788a2a52645 633 PANTHER PTHR19211 1 573 1.5E-232 T 13-09-2016 THL1_RS10580 52f8a7672cf87320c252f788a2a52645 633 SMART SM00382 28 227 1.0E-10 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS10580 52f8a7672cf87320c252f788a2a52645 633 SMART SM00382 342 513 3.8E-14 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS10580 52f8a7672cf87320c252f788a2a52645 633 Pfam PF00005 ABC transporter 19 182 1.4E-22 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS10580 52f8a7672cf87320c252f788a2a52645 633 Pfam PF00005 ABC transporter 334 467 5.2E-22 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS10580 52f8a7672cf87320c252f788a2a52645 633 SUPERFAMILY SSF52540 4 229 1.26E-48 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10580 52f8a7672cf87320c252f788a2a52645 633 SUPERFAMILY SSF52540 305 527 2.5E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10580 52f8a7672cf87320c252f788a2a52645 633 Pfam PF12848 ABC transporter 221 299 1.8E-9 T 13-09-2016 IPR032781 ABC-transporter extension domain THL1_RS10580 52f8a7672cf87320c252f788a2a52645 633 PANTHER PTHR19211:SF45 1 573 1.5E-232 T 13-09-2016 THL1_RS10580 52f8a7672cf87320c252f788a2a52645 633 Gene3D G3DSA:3.40.50.300 2 267 4.4E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10580 52f8a7672cf87320c252f788a2a52645 633 Gene3D G3DSA:3.40.50.300 319 550 4.6E-44 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10580 52f8a7672cf87320c252f788a2a52645 633 Pfam PF16326 ABC transporter C-terminal domain 563 631 9.0E-21 T 13-09-2016 IPR032524 ABC transporter Uup, C-terminal GO:0003677 THL1_RS10580 52f8a7672cf87320c252f788a2a52645 633 ProSitePatterns PS00211 ABC transporters family signature. 439 453 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS10580 52f8a7672cf87320c252f788a2a52645 633 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS12210 0eda5865d7a8838bd2687ed901b4e061 714 Gene3D G3DSA:1.10.287.950 466 683 6.8E-58 T 13-09-2016 THL1_RS12210 0eda5865d7a8838bd2687ed901b4e061 714 SMART SM00304 383 437 2.9E-8 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS12210 0eda5865d7a8838bd2687ed901b4e061 714 PANTHER PTHR32089:SF34 24 714 1.2E-283 T 13-09-2016 THL1_RS12210 0eda5865d7a8838bd2687ed901b4e061 714 SUPERFAMILY SSF58104 405 713 1.7E-81 T 13-09-2016 THL1_RS12210 0eda5865d7a8838bd2687ed901b4e061 714 Pfam PF00672 HAMP domain 364 433 8.0E-14 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS12210 0eda5865d7a8838bd2687ed901b4e061 714 SMART SM00283 452 713 8.7E-83 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS12210 0eda5865d7a8838bd2687ed901b4e061 714 Pfam PF02743 Cache domain 53 333 7.2E-19 T 13-09-2016 IPR033479 Double Cache domain 1 THL1_RS12210 0eda5865d7a8838bd2687ed901b4e061 714 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 520 712 7.0E-51 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS12210 0eda5865d7a8838bd2687ed901b4e061 714 Gene3D G3DSA:3.30.450.20 104 137 1.2E-8 T 13-09-2016 THL1_RS12210 0eda5865d7a8838bd2687ed901b4e061 714 Gene3D G3DSA:3.30.450.20 170 240 1.2E-8 T 13-09-2016 THL1_RS12210 0eda5865d7a8838bd2687ed901b4e061 714 PANTHER PTHR32089 24 714 1.2E-283 T 13-09-2016 THL1_RS23380 bf47516cc1de1aa5cd65887754db3055 543 PANTHER PTHR32089:SF64 188 543 9.3E-130 T 13-09-2016 THL1_RS23380 bf47516cc1de1aa5cd65887754db3055 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 14 39 1.3E-22 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS23380 bf47516cc1de1aa5cd65887754db3055 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 379 406 1.3E-22 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS23380 bf47516cc1de1aa5cd65887754db3055 543 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 408 437 1.3E-22 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS23380 bf47516cc1de1aa5cd65887754db3055 543 SMART SM00304 214 266 8.5E-8 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS23380 bf47516cc1de1aa5cd65887754db3055 543 SMART SM00304 308 361 62.0 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS23380 bf47516cc1de1aa5cd65887754db3055 543 Gene3D G3DSA:1.10.287.950 296 513 3.8E-59 T 13-09-2016 THL1_RS23380 bf47516cc1de1aa5cd65887754db3055 543 PANTHER PTHR32089:SF64 116 165 9.3E-130 T 13-09-2016 THL1_RS23380 bf47516cc1de1aa5cd65887754db3055 543 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 349 540 1.1E-47 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS23380 bf47516cc1de1aa5cd65887754db3055 543 PANTHER PTHR32089 116 165 9.3E-130 T 13-09-2016 THL1_RS23380 bf47516cc1de1aa5cd65887754db3055 543 Pfam PF00672 HAMP domain 195 259 9.0E-13 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS23380 bf47516cc1de1aa5cd65887754db3055 543 PANTHER PTHR32089 188 543 9.3E-130 T 13-09-2016 THL1_RS23380 bf47516cc1de1aa5cd65887754db3055 543 SUPERFAMILY SSF58104 234 542 6.93E-76 T 13-09-2016 THL1_RS23380 bf47516cc1de1aa5cd65887754db3055 543 SMART SM00283 281 542 3.3E-84 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 SMART SM00382 356 500 5.1E-9 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 SUPERFAMILY SSF55781 135 207 5.05E-5 T 13-09-2016 IPR029016 GAF domain-like THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 Gene3D G3DSA:3.30.450.20 238 305 2.3E-6 T 13-09-2016 THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 SUPERFAMILY SSF46689 545 633 9.56E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 SUPERFAMILY SSF52540 336 575 2.11E-59 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 599 616 4.8E-9 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 616 635 4.8E-9 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 Pfam PF02954 Bacterial regulatory protein, Fis family 593 633 9.1E-14 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 Gene3D G3DSA:1.10.8.60 512 580 5.6E-10 T 13-09-2016 THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 SUPERFAMILY SSF55785 234 304 1.35E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 Gene3D G3DSA:3.40.50.300 334 509 9.7E-54 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 Gene3D G3DSA:1.10.10.60 592 632 3.0E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 Pfam PF00158 Sigma-54 interaction domain 337 503 1.8E-63 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 SMART SM00091 227 293 0.0041 T 13-09-2016 IPR000014 PAS domain THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 PANTHER PTHR32071:SF5 258 633 1.4E-122 T 13-09-2016 THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 360 373 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 PANTHER PTHR32071 258 633 1.4E-122 T 13-09-2016 THL1_RS15870 0ff3e7a1faa7bc5b4cdec84f02f5bf23 635 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 423 438 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS25555 d0e542f98282381b5cb05291309bf187 232 Gene3D G3DSA:3.40.50.300 1 221 3.9E-64 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25555 d0e542f98282381b5cb05291309bf187 232 Pfam PF00005 ABC transporter 17 161 3.5E-32 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS25555 d0e542f98282381b5cb05291309bf187 232 PANTHER PTHR24220:SF404 3 232 2.4E-136 T 13-09-2016 THL1_RS25555 d0e542f98282381b5cb05291309bf187 232 PANTHER PTHR24220 3 232 2.4E-136 T 13-09-2016 THL1_RS25555 d0e542f98282381b5cb05291309bf187 232 SUPERFAMILY SSF52540 2 221 1.1E-59 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25555 d0e542f98282381b5cb05291309bf187 232 SMART SM00382 26 211 3.3E-9 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS25555 d0e542f98282381b5cb05291309bf187 232 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 232 8.2E-107 T 13-09-2016 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE THL1_RS00035 e440bdc55967a8eb78987978eabbe681 105 Gene3D G3DSA:1.10.10.60 10 50 3.2E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS00035 e440bdc55967a8eb78987978eabbe681 105 SUPERFAMILY SSF46689 4 67 4.48E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS00035 e440bdc55967a8eb78987978eabbe681 105 Pfam PF01527 Transposase 1 54 2.1E-12 T 13-09-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 THL1_RS17970 e440bdc55967a8eb78987978eabbe681 105 Gene3D G3DSA:1.10.10.60 10 50 3.2E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17970 e440bdc55967a8eb78987978eabbe681 105 SUPERFAMILY SSF46689 4 67 4.48E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17970 e440bdc55967a8eb78987978eabbe681 105 Pfam PF01527 Transposase 1 54 2.1E-12 T 13-09-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 THL1_RS16065 e440bdc55967a8eb78987978eabbe681 105 Gene3D G3DSA:1.10.10.60 10 50 3.2E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS16065 e440bdc55967a8eb78987978eabbe681 105 SUPERFAMILY SSF46689 4 67 4.48E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS16065 e440bdc55967a8eb78987978eabbe681 105 Pfam PF01527 Transposase 1 54 2.1E-12 T 13-09-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 THL1_RS27655 e440bdc55967a8eb78987978eabbe681 105 Gene3D G3DSA:1.10.10.60 10 50 3.2E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS27655 e440bdc55967a8eb78987978eabbe681 105 SUPERFAMILY SSF46689 4 67 4.48E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS27655 e440bdc55967a8eb78987978eabbe681 105 Pfam PF01527 Transposase 1 54 2.1E-12 T 13-09-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 THL1_RS01985 7d8d0cbafc36e96f38446e83b4a179af 108 Pfam PF04267 Sarcosine oxidase, delta subunit family 4 84 2.2E-36 T 13-09-2016 IPR006279 Sarcosine oxidase, delta subunit, heterotetrameric GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 THL1_RS01985 7d8d0cbafc36e96f38446e83b4a179af 108 TIGRFAM TIGR01374 soxD: sarcosine oxidase, delta subunit family 4 87 1.3E-39 T 13-09-2016 IPR006279 Sarcosine oxidase, delta subunit, heterotetrameric GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 THL1_RS06845 f7569caf664ccf62cb76a3b2913c8b22 50 Pfam PF11752 Protein of unknown function (DUF3309) 4 50 9.6E-19 T 13-09-2016 IPR021738 Protein of unknown function DUF3309 THL1_RS24590 c34526193c39383f45b0e5e79a6bd63d 298 PANTHER PTHR30193 7 298 1.4E-104 T 13-09-2016 THL1_RS24590 c34526193c39383f45b0e5e79a6bd63d 298 PANTHER PTHR30193:SF10 7 298 1.4E-104 T 13-09-2016 THL1_RS24590 c34526193c39383f45b0e5e79a6bd63d 298 Gene3D G3DSA:1.10.3720.10 7 283 5.4E-52 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS24590 c34526193c39383f45b0e5e79a6bd63d 298 SUPERFAMILY SSF161098 7 290 2.15E-54 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS24590 c34526193c39383f45b0e5e79a6bd63d 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 284 2.5E-18 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS21640 1d058dd3b175311f55bd28db3246a18d 156 Gene3D G3DSA:3.90.960.10 1 154 2.1E-56 T 13-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THL1_RS21640 1d058dd3b175311f55bd28db3246a18d 156 PANTHER PTHR30411 1 153 3.8E-63 T 13-09-2016 THL1_RS21640 1d058dd3b175311f55bd28db3246a18d 156 PANTHER PTHR30411:SF0 1 153 3.8E-63 T 13-09-2016 THL1_RS21640 1d058dd3b175311f55bd28db3246a18d 156 PIRSF PIRSF006181 1 156 1.2E-53 T 13-09-2016 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC THL1_RS21640 1d058dd3b175311f55bd28db3246a18d 156 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 2 153 5.9E-55 T 13-09-2016 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC THL1_RS21640 1d058dd3b175311f55bd28db3246a18d 156 SUPERFAMILY SSF55826 2 153 1.44E-41 T 13-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THL1_RS21640 1d058dd3b175311f55bd28db3246a18d 156 Pfam PF04073 Aminoacyl-tRNA editing domain 32 142 4.6E-25 T 13-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THL1_RS25455 dea0ae07a64852ffeb97aa7172012f52 592 PANTHER PTHR32234 7 592 2.6E-175 T 13-09-2016 THL1_RS25455 dea0ae07a64852ffeb97aa7172012f52 592 Gene3D G3DSA:2.60.40.1250 33 155 1.2E-38 T 13-09-2016 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain THL1_RS25455 dea0ae07a64852ffeb97aa7172012f52 592 PANTHER PTHR32234:SF0 7 592 2.6E-175 T 13-09-2016 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 THL1_RS25455 dea0ae07a64852ffeb97aa7172012f52 592 Pfam PF13899 Thioredoxin-like 483 561 2.3E-13 T 13-09-2016 THL1_RS25455 dea0ae07a64852ffeb97aa7172012f52 592 Pfam PF11412 Disulphide bond corrector protein DsbC 38 151 7.5E-32 T 13-09-2016 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain THL1_RS25455 dea0ae07a64852ffeb97aa7172012f52 592 SUPERFAMILY SSF52833 480 587 9.77E-19 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS25455 dea0ae07a64852ffeb97aa7172012f52 592 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 181 386 1.7E-9 T 13-09-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 THL1_RS25455 dea0ae07a64852ffeb97aa7172012f52 592 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 1 589 35.019 T 13-09-2016 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 THL1_RS25455 dea0ae07a64852ffeb97aa7172012f52 592 Gene3D G3DSA:3.40.30.10 476 588 2.0E-26 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS25455 dea0ae07a64852ffeb97aa7172012f52 592 SUPERFAMILY SSF74863 35 151 7.19E-35 T 13-09-2016 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain THL1_RS25240 d4b76801337d81ba4126cbe0df893b5e 599 PANTHER PTHR37465:SF1 1 90 4.1E-14 T 13-09-2016 THL1_RS25240 d4b76801337d81ba4126cbe0df893b5e 599 PANTHER PTHR37465 1 90 4.1E-14 T 13-09-2016 THL1_RS25240 d4b76801337d81ba4126cbe0df893b5e 599 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 339 427 4.1E-7 T 13-09-2016 IPR018712 Domain of unknown function DUF2235 THL1_RS25240 d4b76801337d81ba4126cbe0df893b5e 599 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 192 311 5.1E-6 T 13-09-2016 IPR018712 Domain of unknown function DUF2235 THL1_RS25240 d4b76801337d81ba4126cbe0df893b5e 599 Pfam PF05488 PAAR motif 10 73 1.9E-7 T 13-09-2016 IPR008727 PAAR motif THL1_RS11215 b1a138dc0019dfb69cae514800431005 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 28 5.2E-7 T 13-09-2016 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 THL1_RS11215 b1a138dc0019dfb69cae514800431005 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 6 28 1.4E-8 T 13-09-2016 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 THL1_RS22260 cc09bf0690a9c35378ab48fb352d842f 352 PANTHER PTHR10520 7 349 3.6E-216 T 13-09-2016 THL1_RS22260 cc09bf0690a9c35378ab48fb352d842f 352 SUPERFAMILY SSF55326 7 170 2.09E-51 T 13-09-2016 THL1_RS22260 cc09bf0690a9c35378ab48fb352d842f 352 SUPERFAMILY SSF56042 171 342 1.79E-62 T 13-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain THL1_RS22260 cc09bf0690a9c35378ab48fb352d842f 352 Pfam PF02769 AIR synthase related protein, C-terminal domain 177 341 1.1E-39 T 13-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain THL1_RS22260 cc09bf0690a9c35378ab48fb352d842f 352 Pfam PF00586 AIR synthase related protein, N-terminal domain 58 164 3.0E-15 T 13-09-2016 IPR016188 PurM-like, N-terminal domain THL1_RS22260 cc09bf0690a9c35378ab48fb352d842f 352 Gene3D G3DSA:3.90.650.10 171 344 4.7E-67 T 13-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain THL1_RS22260 cc09bf0690a9c35378ab48fb352d842f 352 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 7 346 45.77 T 13-09-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 THL1_RS22260 cc09bf0690a9c35378ab48fb352d842f 352 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 7 335 1.3E-142 T 13-09-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 THL1_RS22260 cc09bf0690a9c35378ab48fb352d842f 352 Gene3D G3DSA:3.30.1330.10 22 170 8.7E-61 T 13-09-2016 IPR016188 PurM-like, N-terminal domain THL1_RS27310 f6bd2713f7a42e55e2477840c446a84e 488 PANTHER PTHR30108:SF1 1 488 5.6E-268 T 13-09-2016 THL1_RS27310 f6bd2713f7a42e55e2477840c446a84e 488 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 431 2.5E-171 T 13-09-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 THL1_RS27310 f6bd2713f7a42e55e2477840c446a84e 488 SUPERFAMILY SSF143968 323 487 1.83E-66 T 13-09-2016 THL1_RS27310 f6bd2713f7a42e55e2477840c446a84e 488 PANTHER PTHR30108 1 488 5.6E-268 T 13-09-2016 THL1_RS27310 f6bd2713f7a42e55e2477840c446a84e 488 Gene3D G3DSA:1.20.5.570 455 487 9.7E-16 T 13-09-2016 THL1_RS27310 f6bd2713f7a42e55e2477840c446a84e 488 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 455 2.9E-171 T 13-09-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 THL1_RS27310 f6bd2713f7a42e55e2477840c446a84e 488 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 1 487 72.022 T 13-09-2016 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 THL1_RS27310 f6bd2713f7a42e55e2477840c446a84e 488 Gene3D G3DSA:3.40.1670.10 337 453 6.4E-55 T 13-09-2016 THL1_RS27310 f6bd2713f7a42e55e2477840c446a84e 488 SUPERFAMILY SSF50475 3 322 1.57E-126 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS24525 2e659e4dd7be875b2ab775bdd0e96e00 159 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 12 136 1.0E-63 T 13-09-2016 IPR000037 SsrA-binding protein GO:0003723 THL1_RS24525 2e659e4dd7be875b2ab775bdd0e96e00 159 Hamap MF_00023 SsrA-binding protein [smpB]. 1 159 70.69 T 13-09-2016 IPR000037 SsrA-binding protein GO:0003723 THL1_RS24525 2e659e4dd7be875b2ab775bdd0e96e00 159 TIGRFAM TIGR00086 smpB: SsrA-binding protein 12 154 7.0E-52 T 13-09-2016 IPR000037 SsrA-binding protein GO:0003723 THL1_RS24525 2e659e4dd7be875b2ab775bdd0e96e00 159 ProSitePatterns PS01317 SsrA-binding protein. 30 42 - T 13-09-2016 IPR020081 SsrA-binding protein, conserved site THL1_RS24525 2e659e4dd7be875b2ab775bdd0e96e00 159 Pfam PF01668 SmpB protein 11 74 8.9E-28 T 13-09-2016 IPR000037 SsrA-binding protein GO:0003723 THL1_RS24525 2e659e4dd7be875b2ab775bdd0e96e00 159 PANTHER PTHR30308:SF2 1 159 2.8E-79 T 13-09-2016 THL1_RS24525 2e659e4dd7be875b2ab775bdd0e96e00 159 PANTHER PTHR30308 1 159 2.8E-79 T 13-09-2016 THL1_RS24525 2e659e4dd7be875b2ab775bdd0e96e00 159 Gene3D G3DSA:2.40.280.10 11 131 5.5E-49 T 13-09-2016 IPR023620 Small protein B THL1_RS24525 2e659e4dd7be875b2ab775bdd0e96e00 159 SUPERFAMILY SSF74982 6 136 9.29E-50 T 13-09-2016 IPR023620 Small protein B THL1_RS02195 bb8184dea955cefd2ce02f1fc0e5e7ec 601 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 468 592 3.7E-36 T 13-09-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain THL1_RS02195 bb8184dea955cefd2ce02f1fc0e5e7ec 601 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 35 7.5E-12 T 13-09-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria THL1_RS02195 bb8184dea955cefd2ce02f1fc0e5e7ec 601 SUPERFAMILY SSF47203 287 475 1.05E-47 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS02195 bb8184dea955cefd2ce02f1fc0e5e7ec 601 Gene3D G3DSA:2.40.110.10 161 268 8.9E-28 T 13-09-2016 THL1_RS02195 bb8184dea955cefd2ce02f1fc0e5e7ec 601 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 282 451 3.2E-20 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS02195 bb8184dea955cefd2ce02f1fc0e5e7ec 601 Gene3D G3DSA:1.20.140.10 269 465 3.9E-47 T 13-09-2016 THL1_RS02195 bb8184dea955cefd2ce02f1fc0e5e7ec 601 PANTHER PTHR10909:SF154 1 478 4.7E-261 T 13-09-2016 THL1_RS02195 bb8184dea955cefd2ce02f1fc0e5e7ec 601 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 40 158 9.8E-13 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS02195 bb8184dea955cefd2ce02f1fc0e5e7ec 601 SUPERFAMILY SSF56645 38 279 1.02E-60 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS02195 bb8184dea955cefd2ce02f1fc0e5e7ec 601 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 163 271 1.8E-18 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS02195 bb8184dea955cefd2ce02f1fc0e5e7ec 601 Gene3D G3DSA:1.10.540.10 36 159 3.8E-19 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS02195 bb8184dea955cefd2ce02f1fc0e5e7ec 601 PANTHER PTHR10909 1 478 4.7E-261 T 13-09-2016 THL1_RS16520 dce77d8e76e55ef9ccb4f0bce0e7631a 382 PANTHER PTHR23514 12 381 8.4E-115 T 13-09-2016 THL1_RS16520 dce77d8e76e55ef9ccb4f0bce0e7631a 382 Gene3D G3DSA:1.20.1250.20 20 185 1.1E-13 T 13-09-2016 THL1_RS16520 dce77d8e76e55ef9ccb4f0bce0e7631a 382 Pfam PF01306 LacY proton/sugar symporter 20 123 2.2E-6 T 13-09-2016 IPR000576 LacY/RafB permease family GO:0006810|GO:0016020 THL1_RS16520 dce77d8e76e55ef9ccb4f0bce0e7631a 382 Gene3D G3DSA:1.20.1250.20 209 374 3.2E-13 T 13-09-2016 THL1_RS16520 dce77d8e76e55ef9ccb4f0bce0e7631a 382 SUPERFAMILY SSF103473 20 381 1.57E-35 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS16520 dce77d8e76e55ef9ccb4f0bce0e7631a 382 Pfam PF07690 Major Facilitator Superfamily 212 374 6.6E-9 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS16520 dce77d8e76e55ef9ccb4f0bce0e7631a 382 PANTHER PTHR23514:SF13 12 381 8.4E-115 T 13-09-2016 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-09-2016 IPR031157 Tr-type G domain, conserved site THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 PANTHER PTHR23115 261 289 0.0 T 13-09-2016 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 PANTHER PTHR23115 3 184 0.0 T 13-09-2016 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 SUPERFAMILY SSF54211 486 606 5.06E-41 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 Gene3D G3DSA:3.40.50.300 7 293 3.4E-100 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 Gene3D G3DSA:2.40.30.10 312 412 3.0E-38 T 13-09-2016 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 PANTHER PTHR23115:SF66 310 699 0.0 T 13-09-2016 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 Pfam PF00679 Elongation factor G C-terminus 608 693 1.6E-29 T 13-09-2016 IPR000640 Translation elongation factor EFG, V domain THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 SUPERFAMILY SSF54980 411 488 6.83E-26 T 13-09-2016 IPR009022 Elongation factor G, III-V domain THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 Gene3D G3DSA:3.30.230.10 491 610 1.6E-46 T 13-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 699 0.0 T 13-09-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 SUPERFAMILY SSF54980 611 697 4.17E-28 T 13-09-2016 IPR009022 Elongation factor G, III-V domain THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 SMART SM00889 487 606 4.4E-68 T 13-09-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 PANTHER PTHR23115:SF66 261 289 0.0 T 13-09-2016 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 SUPERFAMILY SSF52540 6 287 4.79E-103 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 PANTHER PTHR23115:SF66 3 184 0.0 T 13-09-2016 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 Gene3D G3DSA:3.30.70.240 611 698 3.0E-30 T 13-09-2016 IPR000640 Translation elongation factor EFG, V domain THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 Pfam PF03144 Elongation factor Tu domain 2 331 398 9.5E-17 T 13-09-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 Pfam PF00009 Elongation factor Tu GTP binding domain 10 287 6.6E-65 T 13-09-2016 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 187 3.6E-35 T 13-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 PANTHER PTHR23115 310 699 0.0 T 13-09-2016 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 Hamap MF_00054_B Elongation factor G [fusA]. 6 699 108.352 T 13-09-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 Gene3D G3DSA:3.30.70.870 413 487 2.5E-40 T 13-09-2016 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 Pfam PF03764 Elongation factor G, domain IV 486 604 6.2E-44 T 13-09-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 SUPERFAMILY SSF50447 271 411 7.51E-35 T 13-09-2016 IPR009000 Translation protein, beta-barrel domain THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 SMART SM00838 608 695 5.3E-55 T 13-09-2016 IPR000640 Translation elongation factor EFG, V domain THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 Pfam PF14492 Elongation Factor G, domain II 411 485 1.2E-35 T 13-09-2016 IPR009022 Elongation factor G, III-V domain THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 PRINTS PR00315 GTP-binding elongation factor signature 137 146 6.4E-17 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 PRINTS PR00315 GTP-binding elongation factor signature 101 112 6.4E-17 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 PRINTS PR00315 GTP-binding elongation factor signature 58 66 6.4E-17 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 PRINTS PR00315 GTP-binding elongation factor signature 85 95 6.4E-17 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS21815 a7c2b29ce615e55be9af3fcabb2d57d3 700 PRINTS PR00315 GTP-binding elongation factor signature 12 25 6.4E-17 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS03075 cb63365744be8bf62faa237f19d14204 291 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 289 1.5E-99 T 13-09-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family THL1_RS03075 cb63365744be8bf62faa237f19d14204 291 SUPERFAMILY SSF51735 1 290 1.3E-100 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS03075 cb63365744be8bf62faa237f19d14204 291 Gene3D G3DSA:3.40.50.720 1 167 1.0E-30 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS03075 cb63365744be8bf62faa237f19d14204 291 PANTHER PTHR10491 1 290 1.6E-96 T 13-09-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family THL1_RS03075 cb63365744be8bf62faa237f19d14204 291 PANTHER PTHR10491:SF4 1 290 1.6E-96 T 13-09-2016 THL1_RS03075 cb63365744be8bf62faa237f19d14204 291 Gene3D G3DSA:3.90.25.10 218 280 2.7E-30 T 13-09-2016 THL1_RS03075 cb63365744be8bf62faa237f19d14204 291 Gene3D G3DSA:3.90.25.10 168 180 2.7E-30 T 13-09-2016 THL1_RS03075 cb63365744be8bf62faa237f19d14204 291 Pfam PF04321 RmlD substrate binding domain 1 290 4.1E-106 T 13-09-2016 IPR029903 RmlD-like substrate binding domain THL1_RS25860 cef4cf810480c6623cfa79f80c259049 84 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 64 27.384 T 13-09-2016 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 THL1_RS25860 cef4cf810480c6623cfa79f80c259049 84 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 64 4.4E-30 T 13-09-2016 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 THL1_RS25860 cef4cf810480c6623cfa79f80c259049 84 PANTHER PTHR34772:SF1 1 80 8.0E-41 T 13-09-2016 THL1_RS25860 cef4cf810480c6623cfa79f80c259049 84 PANTHER PTHR34772 1 80 8.0E-41 T 13-09-2016 THL1_RS25860 cef4cf810480c6623cfa79f80c259049 84 Gene3D G3DSA:2.30.30.100 1 74 5.3E-37 T 13-09-2016 THL1_RS25860 cef4cf810480c6623cfa79f80c259049 84 SUPERFAMILY SSF50182 7 69 2.5E-24 T 13-09-2016 IPR010920 LSM domain THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 PIRSF PIRSF036643 19 957 0.0 T 13-09-2016 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 171 182 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 SUPERFAMILY SSF50692 781 923 3.39E-40 T 13-09-2016 IPR009010 Aspartate decarboxylase-like domain THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 Pfam PF00384 Molybdopterin oxidoreductase 298 728 4.0E-74 T 13-09-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 PANTHER PTHR11615:SF112 25 73 2.0E-241 T 13-09-2016 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 851 878 - T 13-09-2016 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 PANTHER PTHR11615 239 941 2.0E-241 T 13-09-2016 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 214 225 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 Gene3D G3DSA:2.40.40.20 771 924 1.1E-40 T 13-09-2016 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 SMART SM00926 241 295 7.1E-16 T 13-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 SMART SM00929 105 145 7.1E-19 T 13-09-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 105 144 3.7E-17 T 13-09-2016 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 PANTHER PTHR11615 25 73 2.0E-241 T 13-09-2016 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 Gene3D G3DSA:3.10.20.30 18 75 1.7E-6 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 SUPERFAMILY SSF54862 97 236 4.06E-37 T 13-09-2016 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 SUPERFAMILY SSF54292 24 96 1.97E-18 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 PANTHER PTHR11615:SF112 239 941 2.0E-241 T 13-09-2016 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 Gene3D G3DSA:3.40.228.10 376 567 1.3E-55 T 13-09-2016 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 Pfam PF00037 4Fe-4S binding domain 212 227 4.0E-5 T 13-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 Gene3D G3DSA:2.20.25.90 252 296 6.5E-19 T 13-09-2016 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 Gene3D G3DSA:3.40.50.740 298 375 7.1E-89 T 13-09-2016 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 Gene3D G3DSA:3.40.50.740 568 770 7.1E-89 T 13-09-2016 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 23 99 2.9E-22 T 13-09-2016 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 Gene3D G3DSA:3.30.70.20 220 251 5.4E-4 T 13-09-2016 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 246 921 1.8E-280 T 13-09-2016 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.2.1.2|KEGG: 00680+1.2.1.2|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 SUPERFAMILY SSF53706 241 779 4.06E-195 T 13-09-2016 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 242 292 8.0E-15 T 13-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 Gene3D G3DSA:3.30.70.20 156 219 1.5E-14 T 13-09-2016 THL1_RS01820 9202575f3db3846d4fb3b16aa00ea801 958 Pfam PF01568 Molydopterin dinucleotide binding domain 813 917 1.3E-27 T 13-09-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 THL1_RS25710 424bef1c5877eaf0e507e8fe0e9bec80 299 PANTHER PTHR30537 1 297 1.4E-146 T 13-09-2016 THL1_RS25710 424bef1c5877eaf0e507e8fe0e9bec80 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 2.1E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS25710 424bef1c5877eaf0e507e8fe0e9bec80 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 2.1E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS25710 424bef1c5877eaf0e507e8fe0e9bec80 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 2.1E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS25710 424bef1c5877eaf0e507e8fe0e9bec80 299 Gene3D G3DSA:3.40.190.10 97 179 8.4E-26 T 13-09-2016 THL1_RS25710 424bef1c5877eaf0e507e8fe0e9bec80 299 Gene3D G3DSA:3.40.190.10 180 264 8.5E-37 T 13-09-2016 THL1_RS25710 424bef1c5877eaf0e507e8fe0e9bec80 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 9.6E-22 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS25710 424bef1c5877eaf0e507e8fe0e9bec80 299 SUPERFAMILY SSF53850 95 297 9.41E-38 T 13-09-2016 THL1_RS25710 424bef1c5877eaf0e507e8fe0e9bec80 299 Pfam PF03466 LysR substrate binding domain 93 294 2.4E-39 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS25710 424bef1c5877eaf0e507e8fe0e9bec80 299 Gene3D G3DSA:1.10.10.10 3 83 1.6E-26 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS25710 424bef1c5877eaf0e507e8fe0e9bec80 299 PANTHER PTHR30537:SF15 1 297 1.4E-146 T 13-09-2016 THL1_RS25710 424bef1c5877eaf0e507e8fe0e9bec80 299 SUPERFAMILY SSF46785 5 116 3.24E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS17225 3caccbc1377f52c428f02dbe68bc6d70 327 SUPERFAMILY SSF55785 137 242 4.01E-14 T 13-09-2016 IPR000014 PAS domain THL1_RS17225 3caccbc1377f52c428f02dbe68bc6d70 327 SMART SM00086 199 241 2.4E-5 T 13-09-2016 IPR001610 PAC motif THL1_RS17225 3caccbc1377f52c428f02dbe68bc6d70 327 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 249 323 3.6E-31 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS17225 3caccbc1377f52c428f02dbe68bc6d70 327 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 142 246 5.1E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS17225 3caccbc1377f52c428f02dbe68bc6d70 327 Gene3D G3DSA:1.10.287.950 249 324 7.6E-34 T 13-09-2016 THL1_RS17225 3caccbc1377f52c428f02dbe68bc6d70 327 PANTHER PTHR32089 260 322 1.6E-34 T 13-09-2016 THL1_RS17225 3caccbc1377f52c428f02dbe68bc6d70 327 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 297 326 1.7E-17 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS17225 3caccbc1377f52c428f02dbe68bc6d70 327 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 268 295 1.7E-17 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS17225 3caccbc1377f52c428f02dbe68bc6d70 327 Gene3D G3DSA:3.30.450.20 142 242 1.8E-15 T 13-09-2016 THL1_RS17225 3caccbc1377f52c428f02dbe68bc6d70 327 Pfam PF08447 PAS fold 145 234 5.8E-17 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS17225 3caccbc1377f52c428f02dbe68bc6d70 327 SUPERFAMILY SSF58104 248 322 5.62E-38 T 13-09-2016 THL1_RS21875 a582f95250fa93a18912170a6e992384 389 SUPERFAMILY SSF55961 164 386 4.08E-31 T 13-09-2016 THL1_RS21875 a582f95250fa93a18912170a6e992384 389 Gene3D G3DSA:2.102.10.10 49 156 4.8E-36 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS21875 a582f95250fa93a18912170a6e992384 389 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 186 378 6.9E-18 T 13-09-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 THL1_RS21875 a582f95250fa93a18912170a6e992384 389 PANTHER PTHR21266:SF2 21 379 9.8E-65 T 13-09-2016 THL1_RS21875 a582f95250fa93a18912170a6e992384 389 Gene3D G3DSA:3.90.380.10 157 370 2.3E-18 T 13-09-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 THL1_RS21875 a582f95250fa93a18912170a6e992384 389 PANTHER PTHR21266 21 379 9.8E-65 T 13-09-2016 THL1_RS21875 a582f95250fa93a18912170a6e992384 389 SUPERFAMILY SSF50022 22 163 7.73E-44 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS21875 a582f95250fa93a18912170a6e992384 389 Pfam PF00355 Rieske [2Fe-2S] domain 50 138 1.5E-18 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS21875 a582f95250fa93a18912170a6e992384 389 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 187 209 1.1E-24 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS21875 a582f95250fa93a18912170a6e992384 389 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 64 79 1.1E-24 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS21875 a582f95250fa93a18912170a6e992384 389 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 107 127 1.1E-24 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS21875 a582f95250fa93a18912170a6e992384 389 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 148 174 1.1E-24 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS21875 a582f95250fa93a18912170a6e992384 389 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 34 59 1.1E-24 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS21875 a582f95250fa93a18912170a6e992384 389 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 85 105 1.1E-24 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS07535 d98c51f8700e431a4a996372bb074250 347 Gene3D G3DSA:3.20.20.30 1 347 1.9E-86 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS07535 d98c51f8700e431a4a996372bb074250 347 PANTHER PTHR30137 1 347 1.1E-47 T 13-09-2016 THL1_RS07535 d98c51f8700e431a4a996372bb074250 347 SUPERFAMILY SSF51679 1 347 4.58E-78 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS07535 d98c51f8700e431a4a996372bb074250 347 Pfam PF00296 Luciferase-like monooxygenase 1 317 7.1E-60 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS20395 635a7a8c4c5f1a386b620ace1fe1b402 224 SUPERFAMILY SSF51306 130 212 1.16E-15 T 13-09-2016 IPR015927 Peptidase S24/S26A/S26B/S26C THL1_RS20395 635a7a8c4c5f1a386b620ace1fe1b402 224 SMART SM00530 6 62 7.2E-6 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS20395 635a7a8c4c5f1a386b620ace1fe1b402 224 Pfam PF01381 Helix-turn-helix 12 62 8.4E-7 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS20395 635a7a8c4c5f1a386b620ace1fe1b402 224 Gene3D G3DSA:1.10.260.40 2 65 2.6E-10 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS20395 635a7a8c4c5f1a386b620ace1fe1b402 224 Gene3D G3DSA:2.10.109.10 129 219 1.4E-14 T 13-09-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain THL1_RS20395 635a7a8c4c5f1a386b620ace1fe1b402 224 Pfam PF00717 Peptidase S24-like 135 201 2.8E-11 T 13-09-2016 IPR019759 Peptidase S24/S26A/S26B THL1_RS20395 635a7a8c4c5f1a386b620ace1fe1b402 224 SUPERFAMILY SSF47413 4 63 1.39E-6 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS25075 44746357071639915633b58e6646ddf3 396 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 2 379 9.8E-90 T 13-09-2016 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 THL1_RS25075 44746357071639915633b58e6646ddf3 396 PANTHER PTHR23502:SF19 1 392 4.6E-138 T 13-09-2016 THL1_RS25075 44746357071639915633b58e6646ddf3 396 PANTHER PTHR23502 1 392 4.6E-138 T 13-09-2016 THL1_RS25075 44746357071639915633b58e6646ddf3 396 SUPERFAMILY SSF103473 3 389 6.54E-59 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS25075 44746357071639915633b58e6646ddf3 396 Pfam PF07690 Major Facilitator Superfamily 14 345 5.8E-36 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS25075 44746357071639915633b58e6646ddf3 396 Gene3D G3DSA:1.20.1250.20 5 182 4.8E-28 T 13-09-2016 THL1_RS25075 44746357071639915633b58e6646ddf3 396 Gene3D G3DSA:1.20.1250.20 205 390 1.5E-6 T 13-09-2016 THL1_RS09500 b6d17c86bc7db57fb359adc83cb530b2 449 PANTHER PTHR11119:SF9 18 438 1.7E-165 T 13-09-2016 IPR029940 AzgA purine transporter GO:0005345|GO:0006863 THL1_RS09500 b6d17c86bc7db57fb359adc83cb530b2 449 PANTHER PTHR11119 18 438 1.7E-165 T 13-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS09500 b6d17c86bc7db57fb359adc83cb530b2 449 PIRSF PIRSF005353 13 449 1.3E-172 T 13-09-2016 IPR026033 Purine permease PbuG-like THL1_RS09500 b6d17c86bc7db57fb359adc83cb530b2 449 Pfam PF00860 Permease family 38 411 1.3E-48 T 13-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS13025 86d8c9ba090d14c77473b705dc02c292 415 Gene3D G3DSA:3.40.630.10 9 231 2.5E-104 T 13-09-2016 THL1_RS13025 86d8c9ba090d14c77473b705dc02c292 415 Gene3D G3DSA:3.40.630.10 354 410 2.5E-104 T 13-09-2016 THL1_RS13025 86d8c9ba090d14c77473b705dc02c292 415 PIRSF PIRSF001235 13 414 4.5E-128 T 13-09-2016 IPR010158 Amidase, hydantoinase/carbamoylase GO:0008152|GO:0016813 THL1_RS13025 86d8c9ba090d14c77473b705dc02c292 415 Pfam PF01546 Peptidase family M20/M25/M40 86 409 9.3E-35 T 13-09-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 THL1_RS13025 86d8c9ba090d14c77473b705dc02c292 415 Pfam PF07687 Peptidase dimerisation domain 218 315 4.4E-6 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS13025 86d8c9ba090d14c77473b705dc02c292 415 Gene3D G3DSA:3.30.70.360 232 332 2.1E-34 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS13025 86d8c9ba090d14c77473b705dc02c292 415 SUPERFAMILY SSF55031 219 332 2.84E-25 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS13025 86d8c9ba090d14c77473b705dc02c292 415 SUPERFAMILY SSF53187 11 228 7.93E-81 T 13-09-2016 THL1_RS13025 86d8c9ba090d14c77473b705dc02c292 415 SUPERFAMILY SSF53187 342 411 7.93E-81 T 13-09-2016 THL1_RS13025 86d8c9ba090d14c77473b705dc02c292 415 PANTHER PTHR32494 10 409 1.3E-140 T 13-09-2016 THL1_RS13025 86d8c9ba090d14c77473b705dc02c292 415 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 17 408 2.0E-119 T 13-09-2016 IPR010158 Amidase, hydantoinase/carbamoylase GO:0008152|GO:0016813 THL1_RS20195 38e9031b52cf411411a9ee716e25e6d4 203 Pfam PF04542 Sigma-70 region 2 24 90 1.8E-12 T 13-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS20195 38e9031b52cf411411a9ee716e25e6d4 203 Gene3D G3DSA:1.10.10.10 132 196 6.7E-14 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20195 38e9031b52cf411411a9ee716e25e6d4 203 SUPERFAMILY SSF88946 2 99 7.46E-22 T 13-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS20195 38e9031b52cf411411a9ee716e25e6d4 203 Gene3D G3DSA:1.10.1740.10 2 101 6.2E-25 T 13-09-2016 THL1_RS20195 38e9031b52cf411411a9ee716e25e6d4 203 Pfam PF08281 Sigma-70, region 4 137 190 2.3E-10 T 13-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS20195 38e9031b52cf411411a9ee716e25e6d4 203 PANTHER PTHR30173 1 199 1.3E-36 T 13-09-2016 THL1_RS20195 38e9031b52cf411411a9ee716e25e6d4 203 SUPERFAMILY SSF88659 111 195 3.55E-15 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS20195 38e9031b52cf411411a9ee716e25e6d4 203 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 190 1.6E-24 T 13-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS02345 87f3fdb70b8311f7cd74552bc1bfd05c 304 SUPERFAMILY SSF161098 11 294 2.9E-52 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS02345 87f3fdb70b8311f7cd74552bc1bfd05c 304 PANTHER PTHR30193 7 303 2.0E-105 T 13-09-2016 THL1_RS02345 87f3fdb70b8311f7cd74552bc1bfd05c 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 294 5.0E-18 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS02345 87f3fdb70b8311f7cd74552bc1bfd05c 304 Gene3D G3DSA:1.10.3720.10 11 288 2.4E-50 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS02345 87f3fdb70b8311f7cd74552bc1bfd05c 304 PANTHER PTHR30193:SF10 7 303 2.0E-105 T 13-09-2016 THL1_RS26455 eacdbf45bfa8ae8144e56fa8ce54871f 264 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 14 231 5.1E-76 T 13-09-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THL1_RS26455 eacdbf45bfa8ae8144e56fa8ce54871f 264 PANTHER PTHR30371:SF0 2 264 1.8E-115 T 13-09-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THL1_RS26455 eacdbf45bfa8ae8144e56fa8ce54871f 264 Pfam PF00902 Sec-independent protein translocase protein (TatC) 17 226 2.3E-65 T 13-09-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THL1_RS26455 eacdbf45bfa8ae8144e56fa8ce54871f 264 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 90 108 9.0E-50 T 13-09-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THL1_RS26455 eacdbf45bfa8ae8144e56fa8ce54871f 264 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 108 134 9.0E-50 T 13-09-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THL1_RS26455 eacdbf45bfa8ae8144e56fa8ce54871f 264 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 13 40 9.0E-50 T 13-09-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THL1_RS26455 eacdbf45bfa8ae8144e56fa8ce54871f 264 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 159 187 9.0E-50 T 13-09-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THL1_RS26455 eacdbf45bfa8ae8144e56fa8ce54871f 264 PANTHER PTHR30371 2 264 1.8E-115 T 13-09-2016 THL1_RS26455 eacdbf45bfa8ae8144e56fa8ce54871f 264 ProSitePatterns PS01218 TatC family signature. 159 178 - T 13-09-2016 IPR019820 Sec-independent periplasmic protein translocase, conserved site THL1_RS26455 eacdbf45bfa8ae8144e56fa8ce54871f 264 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 2 244 18.337 T 13-09-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THL1_RS25830 2548d64e40388d9e36af2b898b8d0002 431 PANTHER PTHR11846 1 429 6.7E-253 T 13-09-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 THL1_RS25830 2548d64e40388d9e36af2b898b8d0002 431 Pfam PF00709 Adenylosuccinate synthetase 5 424 4.5E-178 T 13-09-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 THL1_RS25830 2548d64e40388d9e36af2b898b8d0002 431 Gene3D G3DSA:3.40.440.10 197 266 1.3E-69 T 13-09-2016 THL1_RS25830 2548d64e40388d9e36af2b898b8d0002 431 Gene3D G3DSA:3.40.440.10 3 94 1.3E-69 T 13-09-2016 THL1_RS25830 2548d64e40388d9e36af2b898b8d0002 431 SMART SM00788 4 425 0.0 T 13-09-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 THL1_RS25830 2548d64e40388d9e36af2b898b8d0002 431 SUPERFAMILY SSF52540 3 430 3.51E-179 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25830 2548d64e40388d9e36af2b898b8d0002 431 Gene3D G3DSA:1.10.300.10 104 196 9.6E-39 T 13-09-2016 THL1_RS25830 2548d64e40388d9e36af2b898b8d0002 431 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 430 2.4E-186 T 13-09-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 THL1_RS25830 2548d64e40388d9e36af2b898b8d0002 431 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 431 219.788 T 13-09-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 THL1_RS25830 2548d64e40388d9e36af2b898b8d0002 431 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 13-09-2016 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 THL1_RS25830 2548d64e40388d9e36af2b898b8d0002 431 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 13-09-2016 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|UniPathway: UPA00075 THL1_RS25830 2548d64e40388d9e36af2b898b8d0002 431 Gene3D G3DSA:3.90.170.10 267 426 4.5E-69 T 13-09-2016 THL1_RS20225 b5a333b224a7026f8c2c31793a15d924 562 Gene3D G3DSA:3.30.300.30 464 561 1.5E-31 T 13-09-2016 THL1_RS20225 b5a333b224a7026f8c2c31793a15d924 562 ProSitePatterns PS00455 Putative AMP-binding domain signature. 212 223 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS20225 b5a333b224a7026f8c2c31793a15d924 562 Gene3D G3DSA:3.40.50.980 219 386 3.6E-41 T 13-09-2016 THL1_RS20225 b5a333b224a7026f8c2c31793a15d924 562 SUPERFAMILY SSF56801 23 561 1.57E-150 T 13-09-2016 THL1_RS20225 b5a333b224a7026f8c2c31793a15d924 562 Gene3D G3DSA:2.30.38.10 387 460 7.6E-30 T 13-09-2016 THL1_RS20225 b5a333b224a7026f8c2c31793a15d924 562 Pfam PF13193 AMP-binding enzyme C-terminal domain 478 552 3.1E-20 T 13-09-2016 IPR025110 AMP-binding enzyme C-terminal domain THL1_RS20225 b5a333b224a7026f8c2c31793a15d924 562 Gene3D G3DSA:3.40.50.980 23 145 3.1E-34 T 13-09-2016 THL1_RS20225 b5a333b224a7026f8c2c31793a15d924 562 Gene3D G3DSA:3.40.50.980 185 218 3.1E-34 T 13-09-2016 THL1_RS20225 b5a333b224a7026f8c2c31793a15d924 562 Pfam PF00501 AMP-binding enzyme 30 469 2.9E-108 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS20225 b5a333b224a7026f8c2c31793a15d924 562 PANTHER PTHR24096 23 560 1.5E-171 T 13-09-2016 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 Gene3D G3DSA:1.10.3850.10 277 489 1.7E-41 T 13-09-2016 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 Gene3D G3DSA:1.10.3850.10 802 1013 1.2E-46 T 13-09-2016 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 SUPERFAMILY SSF82693 271 326 7.32E-16 T 13-09-2016 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 SUPERFAMILY SSF82693 139 185 7.32E-16 T 13-09-2016 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 Pfam PF00873 AcrB/AcrD/AcrF family 7 1010 5.5E-143 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 Gene3D G3DSA:3.30.70.1430 43 142 7.9E-18 T 13-09-2016 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 SUPERFAMILY SSF82714 709 796 9.29E-11 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 PANTHER PTHR32063:SF18 5 1014 0.0 T 13-09-2016 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 PANTHER PTHR32063 5 1014 0.0 T 13-09-2016 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 SUPERFAMILY SSF82866 793 1013 5.23E-37 T 13-09-2016 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 Gene3D G3DSA:3.30.2090.10 187 270 2.0E-9 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 SUPERFAMILY SSF82866 298 491 1.1E-33 T 13-09-2016 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 SUPERFAMILY SSF82693 43 138 2.79E-15 T 13-09-2016 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 Gene3D G3DSA:3.30.2090.10 709 796 2.3E-9 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 1.1E-19 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 1.1E-19 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 1.1E-19 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 PRINTS PR00702 Acriflavin resistance protein family signature 359 380 1.1E-19 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 1.1E-19 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 SUPERFAMILY SSF82693 556 654 1.05E-7 T 13-09-2016 THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 SUPERFAMILY SSF82714 188 269 1.57E-9 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS20860 b3453a64f6d3b604bcafdcc8557500ac 1027 Gene3D G3DSA:3.30.70.1430 560 656 1.1E-5 T 13-09-2016 THL1_RS02585 9b1d2a47ff23e94c677cadedff5e9848 640 SMART SM00763 19 376 7.8E-213 T 13-09-2016 IPR013153 PrkA AAA domain THL1_RS02585 9b1d2a47ff23e94c677cadedff5e9848 640 PIRSF PIRSF000549 1 640 2.0E-285 T 13-09-2016 IPR016230 Serine-protein kinase, PrkA GO:0004672 THL1_RS02585 9b1d2a47ff23e94c677cadedff5e9848 640 Pfam PF08298 PrkA AAA domain 20 376 6.3E-177 T 13-09-2016 IPR013153 PrkA AAA domain THL1_RS02585 9b1d2a47ff23e94c677cadedff5e9848 640 Pfam PF06798 PrkA serine protein kinase C-terminal domain 379 632 1.8E-75 T 13-09-2016 IPR010650 PrkA C-terminal domain THL1_RS02585 9b1d2a47ff23e94c677cadedff5e9848 640 SUPERFAMILY SSF52540 75 342 5.14E-14 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS02585 9b1d2a47ff23e94c677cadedff5e9848 640 Gene3D G3DSA:3.40.50.300 239 325 3.9E-6 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS02585 9b1d2a47ff23e94c677cadedff5e9848 640 Gene3D G3DSA:3.40.50.300 75 154 3.9E-6 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS02585 9b1d2a47ff23e94c677cadedff5e9848 640 PANTHER PTHR30267 1 640 5.9E-284 T 13-09-2016 THL1_RS02585 9b1d2a47ff23e94c677cadedff5e9848 640 PANTHER PTHR30267:SF2 1 640 5.9E-284 T 13-09-2016 THL1_RS11595 98d119b5625a91af4dd85f215835e889 161 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 61 68 - T 13-09-2016 IPR029760 Glutathione peroxidase conserved site THL1_RS11595 98d119b5625a91af4dd85f215835e889 161 PANTHER PTHR11592 5 161 4.6E-78 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS11595 98d119b5625a91af4dd85f215835e889 161 Pfam PF00255 Glutathione peroxidase 6 112 7.7E-40 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS11595 98d119b5625a91af4dd85f215835e889 161 PIRSF PIRSF000303 1 161 5.5E-63 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS11595 98d119b5625a91af4dd85f215835e889 161 SUPERFAMILY SSF52833 4 161 4.36E-59 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS11595 98d119b5625a91af4dd85f215835e889 161 ProSitePatterns PS00460 Glutathione peroxidases active site. 25 40 - T 13-09-2016 IPR029759 Glutathione peroxidase active site THL1_RS11595 98d119b5625a91af4dd85f215835e889 161 Gene3D G3DSA:3.40.30.10 4 161 1.2E-67 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS11595 98d119b5625a91af4dd85f215835e889 161 PRINTS PR01011 Glutathione peroxidase family signature 58 74 2.7E-20 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS11595 98d119b5625a91af4dd85f215835e889 161 PRINTS PR01011 Glutathione peroxidase family signature 23 40 2.7E-20 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS11595 98d119b5625a91af4dd85f215835e889 161 PRINTS PR01011 Glutathione peroxidase family signature 124 133 2.7E-20 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS00095 fd1e17d224fc2fe46d3d003d9e16f114 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 219 233 7.4E-27 T 13-09-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS00095 fd1e17d224fc2fe46d3d003d9e16f114 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 248 258 7.4E-27 T 13-09-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS00095 fd1e17d224fc2fe46d3d003d9e16f114 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 315 327 7.4E-27 T 13-09-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS00095 fd1e17d224fc2fe46d3d003d9e16f114 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 365 381 7.4E-27 T 13-09-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS00095 fd1e17d224fc2fe46d3d003d9e16f114 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 413 430 7.4E-27 T 13-09-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS00095 fd1e17d224fc2fe46d3d003d9e16f114 437 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 7 430 1.2E-120 T 13-09-2016 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS00095 fd1e17d224fc2fe46d3d003d9e16f114 437 Pfam PF01189 16S rRNA methyltransferase RsmB/F 238 428 6.0E-59 T 13-09-2016 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS00095 fd1e17d224fc2fe46d3d003d9e16f114 437 PANTHER PTHR22807 28 434 7.0E-118 T 13-09-2016 THL1_RS00095 fd1e17d224fc2fe46d3d003d9e16f114 437 PANTHER PTHR22807:SF30 28 434 7.0E-118 T 13-09-2016 THL1_RS00095 fd1e17d224fc2fe46d3d003d9e16f114 437 Pfam PF01029 NusB family 2 123 7.2E-21 T 13-09-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 THL1_RS00095 fd1e17d224fc2fe46d3d003d9e16f114 437 Gene3D G3DSA:3.40.50.150 229 430 4.9E-51 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS00095 fd1e17d224fc2fe46d3d003d9e16f114 437 Gene3D G3DSA:1.10.287.730 145 169 6.2E-12 T 13-09-2016 THL1_RS00095 fd1e17d224fc2fe46d3d003d9e16f114 437 SUPERFAMILY SSF48013 1 146 1.01E-32 T 13-09-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 THL1_RS00095 fd1e17d224fc2fe46d3d003d9e16f114 437 Gene3D G3DSA:3.30.70.1170 170 227 5.1E-25 T 13-09-2016 THL1_RS00095 fd1e17d224fc2fe46d3d003d9e16f114 437 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 314 325 - T 13-09-2016 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS00095 fd1e17d224fc2fe46d3d003d9e16f114 437 Gene3D G3DSA:1.10.940.10 1 144 5.0E-40 T 13-09-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 THL1_RS00095 fd1e17d224fc2fe46d3d003d9e16f114 437 SUPERFAMILY SSF53335 135 431 9.76E-68 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS21100 afa8142c13b766247db6aefc8bb34b34 350 SMART SM00839 149 349 2.0E-63 T 13-09-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 THL1_RS21100 afa8142c13b766247db6aefc8bb34b34 350 Gene3D G3DSA:3.40.50.720 158 340 2.0E-47 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS21100 afa8142c13b766247db6aefc8bb34b34 350 PANTHER PTHR11606 25 347 7.5E-114 T 13-09-2016 THL1_RS21100 afa8142c13b766247db6aefc8bb34b34 350 PIRSF PIRSF000188 1 350 7.8E-138 T 13-09-2016 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 THL1_RS21100 afa8142c13b766247db6aefc8bb34b34 350 SUPERFAMILY SSF53223 4 137 1.06E-44 T 13-09-2016 THL1_RS21100 afa8142c13b766247db6aefc8bb34b34 350 Gene3D G3DSA:3.40.192.10 1 157 1.3E-63 T 13-09-2016 THL1_RS21100 afa8142c13b766247db6aefc8bb34b34 350 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 22 129 2.4E-28 T 13-09-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 THL1_RS21100 afa8142c13b766247db6aefc8bb34b34 350 SUPERFAMILY SSF51735 150 348 2.8E-47 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS21100 afa8142c13b766247db6aefc8bb34b34 350 PANTHER PTHR11606:SF3 25 347 7.5E-114 T 13-09-2016 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 THL1_RS21100 afa8142c13b766247db6aefc8bb34b34 350 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 223 301 4.4E-8 T 13-09-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 THL1_RS21100 afa8142c13b766247db6aefc8bb34b34 350 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 291 302 7.9E-16 T 13-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 THL1_RS21100 afa8142c13b766247db6aefc8bb34b34 350 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 181 201 7.9E-16 T 13-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 THL1_RS21100 afa8142c13b766247db6aefc8bb34b34 350 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 66 80 7.9E-16 T 13-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 THL1_RS21100 afa8142c13b766247db6aefc8bb34b34 350 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 74 87 - T 13-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 THL1_RS27090 4347ac14f1c201a7c53fcdb8e9b395af 299 SUPERFAMILY SSF46785 3 82 5.79E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS27090 4347ac14f1c201a7c53fcdb8e9b395af 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 6.5E-20 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS27090 4347ac14f1c201a7c53fcdb8e9b395af 299 Gene3D G3DSA:3.40.190.10 90 179 1.7E-26 T 13-09-2016 THL1_RS27090 4347ac14f1c201a7c53fcdb8e9b395af 299 Gene3D G3DSA:3.40.190.10 284 292 1.7E-26 T 13-09-2016 THL1_RS27090 4347ac14f1c201a7c53fcdb8e9b395af 299 SUPERFAMILY SSF53850 90 295 7.36E-41 T 13-09-2016 THL1_RS27090 4347ac14f1c201a7c53fcdb8e9b395af 299 PANTHER PTHR30118 1 298 1.2E-118 T 13-09-2016 THL1_RS27090 4347ac14f1c201a7c53fcdb8e9b395af 299 PANTHER PTHR30118:SF4 1 298 1.2E-118 T 13-09-2016 THL1_RS27090 4347ac14f1c201a7c53fcdb8e9b395af 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.6E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS27090 4347ac14f1c201a7c53fcdb8e9b395af 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.6E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS27090 4347ac14f1c201a7c53fcdb8e9b395af 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.6E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS27090 4347ac14f1c201a7c53fcdb8e9b395af 299 Gene3D G3DSA:3.40.190.10 180 267 2.3E-27 T 13-09-2016 THL1_RS27090 4347ac14f1c201a7c53fcdb8e9b395af 299 Pfam PF03466 LysR substrate binding domain 94 294 1.7E-25 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS27090 4347ac14f1c201a7c53fcdb8e9b395af 299 Gene3D G3DSA:1.10.10.10 2 83 3.8E-32 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS16200 677188a97a199dfd2973954f292b8c8e 94 PANTHER PTHR33755 1 94 7.2E-22 T 13-09-2016 THL1_RS16200 677188a97a199dfd2973954f292b8c8e 94 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 89 4.6E-19 T 13-09-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THL1_RS16200 677188a97a199dfd2973954f292b8c8e 94 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 2 84 5.6E-8 T 13-09-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THL1_RS19645 77aac5080af110b3b1b182c46bfa39d6 132 PANTHER PTHR34773 1 124 4.2E-27 T 13-09-2016 THL1_RS19645 77aac5080af110b3b1b182c46bfa39d6 132 TIGRFAM TIGR00208 fliS: flagellar protein FliS 4 118 1.4E-18 T 13-09-2016 IPR003713 Flagellar protein FliS GO:0044780 THL1_RS19645 77aac5080af110b3b1b182c46bfa39d6 132 SUPERFAMILY SSF101116 13 123 3.14E-29 T 13-09-2016 IPR003713 Flagellar protein FliS GO:0044780 THL1_RS19645 77aac5080af110b3b1b182c46bfa39d6 132 Gene3D G3DSA:1.20.120.340 2 123 4.0E-31 T 13-09-2016 IPR003713 Flagellar protein FliS GO:0044780 THL1_RS19645 77aac5080af110b3b1b182c46bfa39d6 132 PIRSF PIRSF039090 1 127 7.5E-37 T 13-09-2016 IPR003713 Flagellar protein FliS GO:0044780 THL1_RS19645 77aac5080af110b3b1b182c46bfa39d6 132 Pfam PF02561 Flagellar protein FliS 6 119 1.6E-28 T 13-09-2016 IPR003713 Flagellar protein FliS GO:0044780 THL1_RS13160 feef4bfbdec8e9d53bfe415e96793411 418 PANTHER PTHR30203 28 414 5.5E-30 T 13-09-2016 THL1_RS13160 feef4bfbdec8e9d53bfe415e96793411 418 Pfam PF02321 Outer membrane efflux protein 32 217 1.5E-15 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS13160 feef4bfbdec8e9d53bfe415e96793411 418 Pfam PF02321 Outer membrane efflux protein 242 411 1.4E-18 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS13160 feef4bfbdec8e9d53bfe415e96793411 418 SUPERFAMILY SSF56954 10 414 4.97E-57 T 13-09-2016 THL1_RS13160 feef4bfbdec8e9d53bfe415e96793411 418 PANTHER PTHR30203:SF1 28 414 5.5E-30 T 13-09-2016 THL1_RS13160 feef4bfbdec8e9d53bfe415e96793411 418 Gene3D G3DSA:1.20.1600.10 27 414 1.2E-38 T 13-09-2016 THL1_RS28420 2f53b2fa9b51861462ac5fad9fb55bcf 458 Gene3D G3DSA:1.10.1140.10 343 458 4.2E-56 T 13-09-2016 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28420 2f53b2fa9b51861462ac5fad9fb55bcf 458 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 128 340 1.5E-63 T 13-09-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28420 2f53b2fa9b51861462ac5fad9fb55bcf 458 PANTHER PTHR15184 1 458 0.0 T 13-09-2016 THL1_RS28420 2f53b2fa9b51861462ac5fad9fb55bcf 458 SUPERFAMILY SSF47917 343 457 2.28E-53 T 13-09-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28420 2f53b2fa9b51861462ac5fad9fb55bcf 458 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 458 56.069 T 13-09-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28420 2f53b2fa9b51861462ac5fad9fb55bcf 458 SUPERFAMILY SSF50615 2 72 3.14E-24 T 13-09-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28420 2f53b2fa9b51861462ac5fad9fb55bcf 458 SMART SM00382 140 325 3.3E-4 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS28420 2f53b2fa9b51861462ac5fad9fb55bcf 458 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 458 3.3E-254 T 13-09-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28420 2f53b2fa9b51861462ac5fad9fb55bcf 458 Gene3D G3DSA:2.40.10.170 2 72 3.9E-28 T 13-09-2016 THL1_RS28420 2f53b2fa9b51861462ac5fad9fb55bcf 458 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 331 340 - T 13-09-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28420 2f53b2fa9b51861462ac5fad9fb55bcf 458 PANTHER PTHR15184:SF44 1 458 0.0 T 13-09-2016 THL1_RS28420 2f53b2fa9b51861462ac5fad9fb55bcf 458 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 71 7.1E-19 T 13-09-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28420 2f53b2fa9b51861462ac5fad9fb55bcf 458 SUPERFAMILY SSF52540 75 346 4.29E-91 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28420 2f53b2fa9b51861462ac5fad9fb55bcf 458 Gene3D G3DSA:3.40.50.300 75 341 1.0E-108 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01410 fa8568f812f999cc39b379d760d0cabf 463 PANTHER PTHR11785 20 455 3.0E-231 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS01410 fa8568f812f999cc39b379d760d0cabf 463 PANTHER PTHR11785:SF346 20 455 3.0E-231 T 13-09-2016 THL1_RS01410 fa8568f812f999cc39b379d760d0cabf 463 PIRSF PIRSF006060 13 455 3.2E-64 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS01410 fa8568f812f999cc39b379d760d0cabf 463 Pfam PF13520 Amino acid permease 39 431 2.8E-36 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS22220 b75f07644c734b6589e29f22f638e740 406 PANTHER PTHR30213:SF0 1 399 4.4E-130 T 13-09-2016 THL1_RS22220 b75f07644c734b6589e29f22f638e740 406 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 1 289 23.73 T 13-09-2016 IPR023679 Uncharacterised protein family UPF0761, bacterial THL1_RS22220 b75f07644c734b6589e29f22f638e740 406 Pfam PF03631 Virulence factor BrkB 22 263 3.3E-58 T 13-09-2016 IPR017039 Virulence factor BrkB THL1_RS22220 b75f07644c734b6589e29f22f638e740 406 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 11 267 5.5E-74 T 13-09-2016 IPR017039 Virulence factor BrkB THL1_RS22220 b75f07644c734b6589e29f22f638e740 406 PANTHER PTHR30213 1 399 4.4E-130 T 13-09-2016 THL1_RS14875 e19315763fe8850aac5f09338ae45b50 105 Gene3D G3DSA:2.40.50.140 8 86 2.1E-26 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS14875 e19315763fe8850aac5f09338ae45b50 105 SUPERFAMILY SSF50249 8 85 1.11E-17 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS14825 e19315763fe8850aac5f09338ae45b50 105 Gene3D G3DSA:2.40.50.140 8 86 2.1E-26 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS14825 e19315763fe8850aac5f09338ae45b50 105 SUPERFAMILY SSF50249 8 85 1.11E-17 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 PANTHER PTHR22912 5 423 4.8E-95 T 13-09-2016 THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 312 2.2E-65 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 Pfam PF14759 Reductase C-terminal 331 414 4.3E-27 T 13-09-2016 IPR028202 Reductase, C-terminal THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 SUPERFAMILY SSF51905 10 171 4.07E-42 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 SUPERFAMILY SSF51905 200 348 4.07E-42 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 Gene3D G3DSA:3.30.390.30 331 419 2.9E-32 T 13-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 SUPERFAMILY SSF55424 327 419 5.49E-28 T 13-09-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 Gene3D G3DSA:3.50.50.60 6 109 2.6E-29 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 PANTHER PTHR22912:SF180 5 423 4.8E-95 T 13-09-2016 THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 4.6E-24 T 13-09-2016 THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 4.6E-24 T 13-09-2016 THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 4.6E-24 T 13-09-2016 THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 258 4.6E-24 T 13-09-2016 THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 4.6E-24 T 13-09-2016 THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 2.4E-15 T 13-09-2016 THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 2.4E-15 T 13-09-2016 THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 243 257 2.4E-15 T 13-09-2016 THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 282 289 2.4E-15 T 13-09-2016 THL1_RS20620 063e2a38cc7daf29bdc8a882522e47d2 425 Gene3D G3DSA:3.50.50.60 110 321 3.0E-43 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS25175 ec104d0724dff7f7be8db6d5d09891f9 330 Gene3D G3DSA:1.10.10.60 278 328 5.4E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS25175 ec104d0724dff7f7be8db6d5d09891f9 330 PANTHER PTHR11019 223 328 3.7E-46 T 13-09-2016 THL1_RS25175 ec104d0724dff7f7be8db6d5d09891f9 330 SMART SM00342 243 325 1.1E-18 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS25175 ec104d0724dff7f7be8db6d5d09891f9 330 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 22 199 2.3E-39 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS25175 ec104d0724dff7f7be8db6d5d09891f9 330 SUPERFAMILY SSF46689 278 327 9.86E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS25175 ec104d0724dff7f7be8db6d5d09891f9 330 PANTHER PTHR11019:SF140 223 328 3.7E-46 T 13-09-2016 THL1_RS25175 ec104d0724dff7f7be8db6d5d09891f9 330 Pfam PF12833 Helix-turn-helix domain 249 326 3.9E-17 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS23345 2b8c47ecf6fe72aef492e29d9fe93de8 688 PANTHER PTHR33121 371 677 1.1E-102 T 13-09-2016 THL1_RS23345 2b8c47ecf6fe72aef492e29d9fe93de8 688 PANTHER PTHR33121 209 218 1.1E-102 T 13-09-2016 THL1_RS23345 2b8c47ecf6fe72aef492e29d9fe93de8 688 Gene3D G3DSA:3.30.70.270 252 419 3.7E-44 T 13-09-2016 THL1_RS23345 2b8c47ecf6fe72aef492e29d9fe93de8 688 Pfam PF00990 Diguanylate cyclase, GGDEF domain 250 407 1.0E-36 T 13-09-2016 IPR000160 GGDEF domain THL1_RS23345 2b8c47ecf6fe72aef492e29d9fe93de8 688 SUPERFAMILY SSF141868 426 675 3.92E-93 T 13-09-2016 IPR001633 EAL domain THL1_RS23345 2b8c47ecf6fe72aef492e29d9fe93de8 688 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 248 409 1.8E-29 T 13-09-2016 IPR000160 GGDEF domain THL1_RS23345 2b8c47ecf6fe72aef492e29d9fe93de8 688 SUPERFAMILY SSF55073 255 411 7.45E-37 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS23345 2b8c47ecf6fe72aef492e29d9fe93de8 688 Pfam PF00563 EAL domain 427 662 1.8E-76 T 13-09-2016 IPR001633 EAL domain THL1_RS23345 2b8c47ecf6fe72aef492e29d9fe93de8 688 Gene3D G3DSA:3.20.20.450 424 674 2.7E-101 T 13-09-2016 IPR001633 EAL domain THL1_RS23345 2b8c47ecf6fe72aef492e29d9fe93de8 688 SMART SM00267 239 411 1.2E-40 T 13-09-2016 IPR000160 GGDEF domain THL1_RS23345 2b8c47ecf6fe72aef492e29d9fe93de8 688 PANTHER PTHR33121:SF13 371 677 1.1E-102 T 13-09-2016 THL1_RS23345 2b8c47ecf6fe72aef492e29d9fe93de8 688 PANTHER PTHR33121:SF13 209 218 1.1E-102 T 13-09-2016 THL1_RS23345 2b8c47ecf6fe72aef492e29d9fe93de8 688 SMART SM00052 421 667 1.4E-119 T 13-09-2016 IPR001633 EAL domain THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 SUPERFAMILY SSF82693 136 183 2.35E-27 T 13-09-2016 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 SUPERFAMILY SSF82693 276 332 2.35E-27 T 13-09-2016 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 4.0E-99 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 4.0E-99 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 PRINTS PR00702 Acriflavin resistance protein family signature 551 568 4.0E-99 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 PRINTS PR00702 Acriflavin resistance protein family signature 9 33 4.0E-99 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 4.0E-99 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 4.0E-99 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 4.0E-99 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 PRINTS PR00702 Acriflavin resistance protein family signature 37 55 4.0E-99 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 PRINTS PR00702 Acriflavin resistance protein family signature 620 634 4.0E-99 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 SUPERFAMILY SSF82714 721 805 1.7E-21 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 SUPERFAMILY SSF82866 830 1026 7.46E-46 T 13-09-2016 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 Gene3D G3DSA:3.30.2090.10 183 277 2.0E-27 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 Gene3D G3DSA:1.10.3850.10 813 1027 1.8E-56 T 13-09-2016 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 Gene3D G3DSA:1.10.3850.10 281 500 2.5E-63 T 13-09-2016 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 Pfam PF00873 AcrB/AcrD/AcrF family 2 1025 0.0 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 SUPERFAMILY SSF82714 184 274 2.35E-21 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 SUPERFAMILY SSF82693 564 670 6.54E-24 T 13-09-2016 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1040 0.0 T 13-09-2016 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 SUPERFAMILY SSF82693 40 132 4.19E-25 T 13-09-2016 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 SUPERFAMILY SSF82693 672 720 5.75E-26 T 13-09-2016 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 SUPERFAMILY SSF82693 807 856 5.75E-26 T 13-09-2016 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 PANTHER PTHR32063:SF11 2 1045 0.0 T 13-09-2016 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 SUPERFAMILY SSF82866 298 499 2.22E-52 T 13-09-2016 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 Gene3D G3DSA:3.30.70.1430 566 670 3.2E-24 T 13-09-2016 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 PANTHER PTHR32063 2 1045 0.0 T 13-09-2016 THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 Gene3D G3DSA:3.30.2090.10 721 805 2.0E-22 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS25080 ff5fc9bc69e2a3f911d4b59373c2c2eb 1046 Gene3D G3DSA:3.30.70.1430 41 140 1.9E-30 T 13-09-2016 THL1_RS25940 ed0a6137644aa2246adb50b9883fb6a5 404 Gene3D G3DSA:3.40.50.1000 256 382 3.1E-42 T 13-09-2016 IPR023214 HAD-like domain THL1_RS25940 ed0a6137644aa2246adb50b9883fb6a5 404 PANTHER PTHR10000:SF7 186 401 5.9E-92 T 13-09-2016 THL1_RS25940 ed0a6137644aa2246adb50b9883fb6a5 404 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 192 362 4.5E-34 T 13-09-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 THL1_RS25940 ed0a6137644aa2246adb50b9883fb6a5 404 Gene3D G3DSA:1.10.150.210 206 255 1.5E-26 T 13-09-2016 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|UniPathway: UPA00135 THL1_RS25940 ed0a6137644aa2246adb50b9883fb6a5 404 PANTHER PTHR10000 186 401 5.9E-92 T 13-09-2016 THL1_RS25940 ed0a6137644aa2246adb50b9883fb6a5 404 Pfam PF13740 ACT domain 3 79 7.3E-26 T 13-09-2016 THL1_RS25940 ed0a6137644aa2246adb50b9883fb6a5 404 Gene3D G3DSA:3.30.70.260 4 87 3.7E-17 T 13-09-2016 THL1_RS25940 ed0a6137644aa2246adb50b9883fb6a5 404 Gene3D G3DSA:3.30.70.260 113 192 7.4E-11 T 13-09-2016 THL1_RS25940 ed0a6137644aa2246adb50b9883fb6a5 404 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 179 395 6.4E-80 T 13-09-2016 THL1_RS25940 ed0a6137644aa2246adb50b9883fb6a5 404 SUPERFAMILY SSF55021 3 83 1.03E-13 T 13-09-2016 THL1_RS25940 ed0a6137644aa2246adb50b9883fb6a5 404 Pfam PF12710 haloacid dehalogenase-like hydrolase 193 360 3.4E-25 T 13-09-2016 THL1_RS25940 ed0a6137644aa2246adb50b9883fb6a5 404 SUPERFAMILY SSF56784 188 395 4.8E-53 T 13-09-2016 IPR023214 HAD-like domain THL1_RS26690 27f50a17dd30f7a056320386c9c5d5ad 153 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 1 150 2.1E-57 T 13-09-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 THL1_RS26690 27f50a17dd30f7a056320386c9c5d5ad 153 Pfam PF00588 SpoU rRNA Methylase family 2 142 1.6E-32 T 13-09-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 THL1_RS26690 27f50a17dd30f7a056320386c9c5d5ad 153 Gene3D G3DSA:3.40.1280.10 1 150 8.2E-66 T 13-09-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THL1_RS26690 27f50a17dd30f7a056320386c9c5d5ad 153 SUPERFAMILY SSF75217 1 150 1.5E-44 T 13-09-2016 IPR029028 Alpha/beta knot methyltransferases THL1_RS26690 27f50a17dd30f7a056320386c9c5d5ad 153 PANTHER PTHR12029:SF31 1 151 4.6E-74 T 13-09-2016 THL1_RS26690 27f50a17dd30f7a056320386c9c5d5ad 153 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 33.963 T 13-09-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 THL1_RS26690 27f50a17dd30f7a056320386c9c5d5ad 153 PIRSF PIRSF029256 1 153 5.0E-67 T 13-09-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 THL1_RS26690 27f50a17dd30f7a056320386c9c5d5ad 153 PANTHER PTHR12029 1 151 4.6E-74 T 13-09-2016 THL1_RS07180 d124eeed0754ce7f7a759d8bd791883c 281 SUPERFAMILY SSF53335 81 273 9.77E-57 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS07180 d124eeed0754ce7f7a759d8bd791883c 281 Gene3D G3DSA:3.40.50.150 80 273 1.5E-66 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS07180 d124eeed0754ce7f7a759d8bd791883c 281 PIRSF PIRSF000410 4 277 7.9E-96 T 13-09-2016 IPR026024 Chemotaxis protein methyltransferase CheR THL1_RS07180 d124eeed0754ce7f7a759d8bd791883c 281 SMART SM00138 15 275 1.7E-91 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS07180 d124eeed0754ce7f7a759d8bd791883c 281 Pfam PF03705 CheR methyltransferase, all-alpha domain 17 68 1.1E-16 T 13-09-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THL1_RS07180 d124eeed0754ce7f7a759d8bd791883c 281 Pfam PF01739 CheR methyltransferase, SAM binding domain 81 268 2.8E-56 T 13-09-2016 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal THL1_RS07180 d124eeed0754ce7f7a759d8bd791883c 281 SUPERFAMILY SSF47757 9 80 2.75E-20 T 13-09-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THL1_RS07180 d124eeed0754ce7f7a759d8bd791883c 281 Gene3D G3DSA:1.10.155.10 8 79 1.5E-26 T 13-09-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THL1_RS07180 d124eeed0754ce7f7a759d8bd791883c 281 PANTHER PTHR24422:SF13 1 266 7.4E-119 T 13-09-2016 THL1_RS07180 d124eeed0754ce7f7a759d8bd791883c 281 PRINTS PR00996 Glutamate methyltransferase family signature 110 130 7.1E-43 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS07180 d124eeed0754ce7f7a759d8bd791883c 281 PRINTS PR00996 Glutamate methyltransferase family signature 235 258 7.1E-43 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS07180 d124eeed0754ce7f7a759d8bd791883c 281 PRINTS PR00996 Glutamate methyltransferase family signature 144 160 7.1E-43 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS07180 d124eeed0754ce7f7a759d8bd791883c 281 PRINTS PR00996 Glutamate methyltransferase family signature 216 230 7.1E-43 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS07180 d124eeed0754ce7f7a759d8bd791883c 281 PRINTS PR00996 Glutamate methyltransferase family signature 74 86 7.1E-43 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS07180 d124eeed0754ce7f7a759d8bd791883c 281 PRINTS PR00996 Glutamate methyltransferase family signature 37 50 7.1E-43 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS07180 d124eeed0754ce7f7a759d8bd791883c 281 PANTHER PTHR24422 1 266 7.4E-119 T 13-09-2016 THL1_RS17105 22e6f7159f5fb9f96c1f52fa5bb6db57 539 Gene3D G3DSA:1.10.287.950 292 508 7.4E-51 T 13-09-2016 THL1_RS17105 22e6f7159f5fb9f96c1f52fa5bb6db57 539 SUPERFAMILY SSF58104 230 539 1.83E-65 T 13-09-2016 THL1_RS17105 22e6f7159f5fb9f96c1f52fa5bb6db57 539 SMART SM00283 277 538 5.0E-61 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS17105 22e6f7159f5fb9f96c1f52fa5bb6db57 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 80 95 6.1E-23 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS17105 22e6f7159f5fb9f96c1f52fa5bb6db57 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 404 433 6.1E-23 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS17105 22e6f7159f5fb9f96c1f52fa5bb6db57 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 375 402 6.1E-23 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS17105 22e6f7159f5fb9f96c1f52fa5bb6db57 539 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 347 537 1.9E-39 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS17105 22e6f7159f5fb9f96c1f52fa5bb6db57 539 SMART SM00304 208 262 7.6E-9 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS17105 22e6f7159f5fb9f96c1f52fa5bb6db57 539 PANTHER PTHR32089 109 539 2.5E-91 T 13-09-2016 THL1_RS17105 22e6f7159f5fb9f96c1f52fa5bb6db57 539 Pfam PF00672 HAMP domain 190 258 3.3E-10 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS25885 a8658226d7a0cca2bab26e83d56b49e6 499 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 18 210 1.5E-39 T 13-09-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 THL1_RS25885 a8658226d7a0cca2bab26e83d56b49e6 499 Pfam PF01256 Carbohydrate kinase 250 487 2.7E-59 T 13-09-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 THL1_RS25885 a8658226d7a0cca2bab26e83d56b49e6 499 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 433 443 - T 13-09-2016 IPR017953 Carbohydrate kinase, predicted, conserved site THL1_RS25885 a8658226d7a0cca2bab26e83d56b49e6 499 PANTHER PTHR12592 1 499 1.0E-132 T 13-09-2016 THL1_RS25885 a8658226d7a0cca2bab26e83d56b49e6 499 Gene3D G3DSA:3.40.50.10260 12 239 1.9E-62 T 13-09-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 THL1_RS25885 a8658226d7a0cca2bab26e83d56b49e6 499 SUPERFAMILY SSF64153 12 249 1.7E-60 T 13-09-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 THL1_RS25885 a8658226d7a0cca2bab26e83d56b49e6 499 Gene3D G3DSA:3.40.1190.20 240 493 1.2E-85 T 13-09-2016 IPR029056 Ribokinase-like THL1_RS25885 a8658226d7a0cca2bab26e83d56b49e6 499 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 14 213 22.035 T 13-09-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 THL1_RS25885 a8658226d7a0cca2bab26e83d56b49e6 499 SUPERFAMILY SSF53613 233 493 6.93E-71 T 13-09-2016 IPR029056 Ribokinase-like THL1_RS25885 a8658226d7a0cca2bab26e83d56b49e6 499 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 228 491 5.7E-68 T 13-09-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 THL1_RS25885 a8658226d7a0cca2bab26e83d56b49e6 499 PIRSF PIRSF017184 10 496 1.8E-128 T 13-09-2016 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 THL1_RS25885 a8658226d7a0cca2bab26e83d56b49e6 499 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 227 496 22.317 T 13-09-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 THL1_RS25885 a8658226d7a0cca2bab26e83d56b49e6 499 Pfam PF03853 YjeF-related protein N-terminus 34 191 2.9E-39 T 13-09-2016 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 THL1_RS25885 a8658226d7a0cca2bab26e83d56b49e6 499 PANTHER PTHR12592:SF0 1 499 1.0E-132 T 13-09-2016 THL1_RS07205 5c9eee46bbc1a03fc795529f98ea1f51 384 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 218 247 4.8E-17 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS07205 5c9eee46bbc1a03fc795529f98ea1f51 384 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 189 216 4.8E-17 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS07205 5c9eee46bbc1a03fc795529f98ea1f51 384 PANTHER PTHR32089 156 300 1.6E-34 T 13-09-2016 THL1_RS07205 5c9eee46bbc1a03fc795529f98ea1f51 384 SUPERFAMILY SSF58104 76 324 1.23E-39 T 13-09-2016 THL1_RS07205 5c9eee46bbc1a03fc795529f98ea1f51 384 SMART SM00283 103 338 4.6E-11 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS07205 5c9eee46bbc1a03fc795529f98ea1f51 384 Gene3D G3DSA:1.10.287.950 106 300 1.1E-37 T 13-09-2016 THL1_RS07205 5c9eee46bbc1a03fc795529f98ea1f51 384 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 160 314 1.9E-28 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS00675 3e05e0df5529b1c8e4f72b3f0fbb0ec6 231 Pfam PF13545 Crp-like helix-turn-helix domain 154 225 8.7E-14 T 13-09-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THL1_RS00675 3e05e0df5529b1c8e4f72b3f0fbb0ec6 231 Gene3D G3DSA:1.10.10.10 152 228 1.2E-15 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00675 3e05e0df5529b1c8e4f72b3f0fbb0ec6 231 Pfam PF00027 Cyclic nucleotide-binding domain 35 121 9.4E-21 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS00675 3e05e0df5529b1c8e4f72b3f0fbb0ec6 231 SMART SM00100 16 134 5.9E-14 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS00675 3e05e0df5529b1c8e4f72b3f0fbb0ec6 231 PANTHER PTHR24567 1 228 1.3E-45 T 13-09-2016 THL1_RS00675 3e05e0df5529b1c8e4f72b3f0fbb0ec6 231 PANTHER PTHR24567:SF30 1 228 1.3E-45 T 13-09-2016 THL1_RS00675 3e05e0df5529b1c8e4f72b3f0fbb0ec6 231 SMART SM00419 171 219 4.1E-6 T 13-09-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THL1_RS00675 3e05e0df5529b1c8e4f72b3f0fbb0ec6 231 SUPERFAMILY SSF51206 11 141 3.27E-31 T 13-09-2016 IPR018490 Cyclic nucleotide-binding-like THL1_RS00675 3e05e0df5529b1c8e4f72b3f0fbb0ec6 231 SUPERFAMILY SSF46785 152 228 1.56E-14 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00675 3e05e0df5529b1c8e4f72b3f0fbb0ec6 231 Gene3D G3DSA:2.60.120.10 16 148 3.7E-30 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS02435 7e236e91af9e49cabf449d454e1133ff 244 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS02435 7e236e91af9e49cabf449d454e1133ff 244 PIRSF PIRSF039085 1 244 2.8E-105 T 13-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 THL1_RS02435 7e236e91af9e49cabf449d454e1133ff 244 SMART SM00382 30 217 7.7E-17 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS02435 7e236e91af9e49cabf449d454e1133ff 244 Gene3D G3DSA:3.40.50.300 1 240 1.1E-83 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS02435 7e236e91af9e49cabf449d454e1133ff 244 Pfam PF00005 ABC transporter 22 169 1.5E-37 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS02435 7e236e91af9e49cabf449d454e1133ff 244 PANTHER PTHR24220:SF474 3 244 2.9E-137 T 13-09-2016 THL1_RS02435 7e236e91af9e49cabf449d454e1133ff 244 PANTHER PTHR24220 3 244 2.9E-137 T 13-09-2016 THL1_RS02435 7e236e91af9e49cabf449d454e1133ff 244 SUPERFAMILY SSF52540 1 239 1.82E-81 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27645 6320e9ae356a896c7faa803fa2d77f58 508 Pfam PF03050 Transposase IS66 family 178 459 5.0E-105 T 13-09-2016 IPR004291 Transposase, IS66 THL1_RS27645 6320e9ae356a896c7faa803fa2d77f58 508 Pfam PF13007 Transposase C of IS166 homeodomain 42 115 2.7E-14 T 13-09-2016 IPR024463 Transposase TnpC, homeodomain THL1_RS27645 6320e9ae356a896c7faa803fa2d77f58 508 PANTHER PTHR33678 15 502 5.4E-96 T 13-09-2016 THL1_RS27645 6320e9ae356a896c7faa803fa2d77f58 508 PANTHER PTHR33678:SF1 15 502 5.4E-96 T 13-09-2016 THL1_RS27645 6320e9ae356a896c7faa803fa2d77f58 508 Pfam PF13817 IS66 C-terminal element 466 503 1.1E-16 T 13-09-2016 THL1_RS27645 6320e9ae356a896c7faa803fa2d77f58 508 Pfam PF13005 zinc-finger binding domain of transposase IS66 122 164 8.6E-14 T 13-09-2016 IPR024474 Zinc-finger binding domain of transposase IS66 THL1_RS16055 6320e9ae356a896c7faa803fa2d77f58 508 Pfam PF03050 Transposase IS66 family 178 459 5.0E-105 T 13-09-2016 IPR004291 Transposase, IS66 THL1_RS16055 6320e9ae356a896c7faa803fa2d77f58 508 Pfam PF13007 Transposase C of IS166 homeodomain 42 115 2.7E-14 T 13-09-2016 IPR024463 Transposase TnpC, homeodomain THL1_RS16055 6320e9ae356a896c7faa803fa2d77f58 508 PANTHER PTHR33678 15 502 5.4E-96 T 13-09-2016 THL1_RS16055 6320e9ae356a896c7faa803fa2d77f58 508 PANTHER PTHR33678:SF1 15 502 5.4E-96 T 13-09-2016 THL1_RS16055 6320e9ae356a896c7faa803fa2d77f58 508 Pfam PF13817 IS66 C-terminal element 466 503 1.1E-16 T 13-09-2016 THL1_RS16055 6320e9ae356a896c7faa803fa2d77f58 508 Pfam PF13005 zinc-finger binding domain of transposase IS66 122 164 8.6E-14 T 13-09-2016 IPR024474 Zinc-finger binding domain of transposase IS66 THL1_RS17960 6320e9ae356a896c7faa803fa2d77f58 508 Pfam PF03050 Transposase IS66 family 178 459 5.0E-105 T 13-09-2016 IPR004291 Transposase, IS66 THL1_RS17960 6320e9ae356a896c7faa803fa2d77f58 508 Pfam PF13007 Transposase C of IS166 homeodomain 42 115 2.7E-14 T 13-09-2016 IPR024463 Transposase TnpC, homeodomain THL1_RS17960 6320e9ae356a896c7faa803fa2d77f58 508 PANTHER PTHR33678 15 502 5.4E-96 T 13-09-2016 THL1_RS17960 6320e9ae356a896c7faa803fa2d77f58 508 PANTHER PTHR33678:SF1 15 502 5.4E-96 T 13-09-2016 THL1_RS17960 6320e9ae356a896c7faa803fa2d77f58 508 Pfam PF13817 IS66 C-terminal element 466 503 1.1E-16 T 13-09-2016 THL1_RS17960 6320e9ae356a896c7faa803fa2d77f58 508 Pfam PF13005 zinc-finger binding domain of transposase IS66 122 164 8.6E-14 T 13-09-2016 IPR024474 Zinc-finger binding domain of transposase IS66 THL1_RS00025 6320e9ae356a896c7faa803fa2d77f58 508 Pfam PF03050 Transposase IS66 family 178 459 5.0E-105 T 13-09-2016 IPR004291 Transposase, IS66 THL1_RS00025 6320e9ae356a896c7faa803fa2d77f58 508 Pfam PF13007 Transposase C of IS166 homeodomain 42 115 2.7E-14 T 13-09-2016 IPR024463 Transposase TnpC, homeodomain THL1_RS00025 6320e9ae356a896c7faa803fa2d77f58 508 PANTHER PTHR33678 15 502 5.4E-96 T 13-09-2016 THL1_RS00025 6320e9ae356a896c7faa803fa2d77f58 508 PANTHER PTHR33678:SF1 15 502 5.4E-96 T 13-09-2016 THL1_RS00025 6320e9ae356a896c7faa803fa2d77f58 508 Pfam PF13817 IS66 C-terminal element 466 503 1.1E-16 T 13-09-2016 THL1_RS00025 6320e9ae356a896c7faa803fa2d77f58 508 Pfam PF13005 zinc-finger binding domain of transposase IS66 122 164 8.6E-14 T 13-09-2016 IPR024474 Zinc-finger binding domain of transposase IS66 THL1_RS06935 b39ddb7aefdd7bde5e1113832e4abc2b 394 PANTHER PTHR18919:SF14 1 394 5.1E-195 T 13-09-2016 THL1_RS06935 b39ddb7aefdd7bde5e1113832e4abc2b 394 Gene3D G3DSA:3.40.47.10 3 125 1.2E-60 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS06935 b39ddb7aefdd7bde5e1113832e4abc2b 394 Gene3D G3DSA:3.40.47.10 185 274 1.2E-60 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS06935 b39ddb7aefdd7bde5e1113832e4abc2b 394 Pfam PF00108 Thiolase, N-terminal domain 4 261 2.8E-65 T 13-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THL1_RS06935 b39ddb7aefdd7bde5e1113832e4abc2b 394 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 13-09-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 THL1_RS06935 b39ddb7aefdd7bde5e1113832e4abc2b 394 Pfam PF02803 Thiolase, C-terminal domain 270 391 2.7E-46 T 13-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THL1_RS06935 b39ddb7aefdd7bde5e1113832e4abc2b 394 SUPERFAMILY SSF53901 1 266 1.67E-70 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS06935 b39ddb7aefdd7bde5e1113832e4abc2b 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 7.7E-133 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS06935 b39ddb7aefdd7bde5e1113832e4abc2b 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 13-09-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 THL1_RS06935 b39ddb7aefdd7bde5e1113832e4abc2b 394 PANTHER PTHR18919 1 394 5.1E-195 T 13-09-2016 THL1_RS06935 b39ddb7aefdd7bde5e1113832e4abc2b 394 Gene3D G3DSA:3.40.47.10 277 391 1.2E-62 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS06935 b39ddb7aefdd7bde5e1113832e4abc2b 394 Gene3D G3DSA:3.40.47.10 145 184 1.2E-62 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS06935 b39ddb7aefdd7bde5e1113832e4abc2b 394 SUPERFAMILY SSF53901 271 391 3.09E-41 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS06935 b39ddb7aefdd7bde5e1113832e4abc2b 394 PIRSF PIRSF000429 1 394 1.2E-124 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS10435 121e71fc13e201dcb95f1b99b9cb7efd 78 PANTHER PTHR34386:SF2 1 78 7.3E-25 T 13-09-2016 THL1_RS10435 121e71fc13e201dcb95f1b99b9cb7efd 78 Gene3D G3DSA:3.40.30.10 4 77 1.3E-21 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS10435 121e71fc13e201dcb95f1b99b9cb7efd 78 PANTHER PTHR34386 1 78 7.3E-25 T 13-09-2016 THL1_RS10435 121e71fc13e201dcb95f1b99b9cb7efd 78 SUPERFAMILY SSF52833 7 77 1.12E-11 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS10435 121e71fc13e201dcb95f1b99b9cb7efd 78 Pfam PF05768 Glutaredoxin-like domain (DUF836) 5 77 5.4E-14 T 13-09-2016 IPR008554 Glutaredoxin-like THL1_RS14260 44b52acfd49b3b3a706398c020a0b8aa 304 Pfam PF12706 Beta-lactamase superfamily domain 51 271 9.4E-48 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS14260 44b52acfd49b3b3a706398c020a0b8aa 304 TIGRFAM TIGR02108 PQQ_syn_pqqB: coenzyme PQQ biosynthesis protein B 2 304 6.5E-139 T 13-09-2016 IPR011842 Coenzyme PQQ biosynthesis protein B GO:0006810|GO:0018189 UniPathway: UPA00539 THL1_RS14260 44b52acfd49b3b3a706398c020a0b8aa 304 Gene3D G3DSA:3.60.15.10 1 304 3.8E-122 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS14260 44b52acfd49b3b3a706398c020a0b8aa 304 Hamap MF_00653 Coenzyme PQQ synthesis protein B [pqqB]. 1 304 177.121 T 13-09-2016 IPR011842 Coenzyme PQQ biosynthesis protein B GO:0006810|GO:0018189 UniPathway: UPA00539 THL1_RS14260 44b52acfd49b3b3a706398c020a0b8aa 304 SUPERFAMILY SSF56281 1 304 4.06E-66 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS01995 0c41779c113e41919fe2ff062a0f4aa5 209 TIGRFAM TIGR01375 soxG: sarcosine oxidase, gamma subunit family 52 202 7.9E-55 T 13-09-2016 IPR006280 Sarcosine oxidase, gamma subunit, heterotetrameric KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 THL1_RS01995 0c41779c113e41919fe2ff062a0f4aa5 209 Pfam PF04268 Sarcosine oxidase, gamma subunit family 52 202 1.5E-53 T 13-09-2016 IPR007375 Sarcosine oxidase, gamma subunit KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 THL1_RS01995 0c41779c113e41919fe2ff062a0f4aa5 209 Gene3D G3DSA:3.30.1360.120 119 205 8.4E-8 T 13-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THL1_RS01995 0c41779c113e41919fe2ff062a0f4aa5 209 SUPERFAMILY SSF103025 82 205 1.32E-24 T 13-09-2016 THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 ProSitePatterns PS00622 LuxR-type HTH domain signature. 854 881 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 Pfam PF00196 Bacterial regulatory proteins, luxR family 841 892 5.8E-18 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 PANTHER PTHR26402 824 902 1.1E-23 T 13-09-2016 THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 PANTHER PTHR26402:SF579 824 902 1.1E-23 T 13-09-2016 THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 Gene3D G3DSA:1.10.10.10 832 899 1.4E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 Gene3D G3DSA:1.25.40.10 463 821 1.1E-12 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 854 870 1.1E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 840 854 1.1E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 870 882 1.1E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 PANTHER PTHR26402 25 37 1.1E-23 T 13-09-2016 THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 Pfam PF13191 AAA ATPase domain 34 172 4.5E-10 T 13-09-2016 THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 SUPERFAMILY SSF52540 34 86 6.35E-8 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 SUPERFAMILY SSF52540 122 257 6.35E-8 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 PANTHER PTHR26402:SF579 25 37 1.1E-23 T 13-09-2016 THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 SMART SM00421 837 894 5.1E-23 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 SUPERFAMILY SSF46894 831 900 1.19E-18 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 Gene3D G3DSA:3.40.50.300 32 89 5.5E-5 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11860 9d910974c4c4f79379663f37b853ddf7 903 Gene3D G3DSA:3.40.50.300 128 180 5.5E-5 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03320 1d79022b6b6a721ee58a722d0902a24c 214 SUPERFAMILY SSF51206 13 141 4.32E-37 T 13-09-2016 IPR018490 Cyclic nucleotide-binding-like THL1_RS03320 1d79022b6b6a721ee58a722d0902a24c 214 SMART SM00100 4 126 1.7E-25 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS03320 1d79022b6b6a721ee58a722d0902a24c 214 ProSitePatterns PS00042 Crp-type HTH domain signature. 172 195 - T 13-09-2016 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 THL1_RS03320 1d79022b6b6a721ee58a722d0902a24c 214 PANTHER PTHR24567 1 211 2.3E-134 T 13-09-2016 THL1_RS03320 1d79022b6b6a721ee58a722d0902a24c 214 SMART SM00419 164 212 6.6E-15 T 13-09-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THL1_RS03320 1d79022b6b6a721ee58a722d0902a24c 214 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 72 93 - T 13-09-2016 IPR018488 Cyclic nucleotide-binding, conserved site THL1_RS03320 1d79022b6b6a721ee58a722d0902a24c 214 SUPERFAMILY SSF46785 143 211 7.34E-16 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS03320 1d79022b6b6a721ee58a722d0902a24c 214 PANTHER PTHR24567:SF27 1 211 2.3E-134 T 13-09-2016 THL1_RS03320 1d79022b6b6a721ee58a722d0902a24c 214 Gene3D G3DSA:2.60.120.10 12 141 5.7E-41 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS03320 1d79022b6b6a721ee58a722d0902a24c 214 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 31 47 - T 13-09-2016 IPR018488 Cyclic nucleotide-binding, conserved site THL1_RS03320 1d79022b6b6a721ee58a722d0902a24c 214 Pfam PF00325 Bacterial regulatory proteins, crp family 170 200 2.9E-14 T 13-09-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THL1_RS03320 1d79022b6b6a721ee58a722d0902a24c 214 Gene3D G3DSA:1.10.10.10 143 211 6.6E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS03320 1d79022b6b6a721ee58a722d0902a24c 214 Pfam PF00027 Cyclic nucleotide-binding domain 22 114 4.3E-23 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS03320 1d79022b6b6a721ee58a722d0902a24c 214 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 186 201 3.3E-9 T 13-09-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THL1_RS03320 1d79022b6b6a721ee58a722d0902a24c 214 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 170 186 3.3E-9 T 13-09-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THL1_RS15495 c31c5af6a29c010b9cf01620eeb58f9f 174 Pfam PF02975 Methylamine dehydrogenase, L chain 61 171 5.3E-53 T 13-09-2016 IPR013504 Methylamine/Aralkylamine dehydrogenase light chain, C-terminal domain GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967|UniPathway: UPA00895 THL1_RS15495 c31c5af6a29c010b9cf01620eeb58f9f 174 SUPERFAMILY SSF57561 59 173 7.59E-53 T 13-09-2016 IPR013504 Methylamine/Aralkylamine dehydrogenase light chain, C-terminal domain GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967|UniPathway: UPA00895 THL1_RS15495 c31c5af6a29c010b9cf01620eeb58f9f 174 Gene3D G3DSA:2.60.30.10 37 173 2.7E-56 T 13-09-2016 IPR013504 Methylamine/Aralkylamine dehydrogenase light chain, C-terminal domain GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967|UniPathway: UPA00895 THL1_RS15495 c31c5af6a29c010b9cf01620eeb58f9f 174 PIRSF PIRSF000192 2 174 8.1E-50 T 13-09-2016 IPR016008 Amine dehydrogenase light chain GO:0009308|GO:0030058|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967|UniPathway: UPA00895 THL1_RS20975 8566cd61d811cd8e6e0207de27f4ae65 53 SUPERFAMILY SSF57802 1 52 1.68E-21 T 13-09-2016 THL1_RS20975 8566cd61d811cd8e6e0207de27f4ae65 53 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 13-09-2016 IPR018527 Rubredoxin, iron-binding site GO:0046872 THL1_RS20975 8566cd61d811cd8e6e0207de27f4ae65 53 Pfam PF00301 Rubredoxin 3 49 1.0E-22 T 13-09-2016 IPR024935 Rubredoxin domain GO:0005506 THL1_RS20975 8566cd61d811cd8e6e0207de27f4ae65 53 PIRSF PIRSF000071 1 53 8.0E-25 T 13-09-2016 IPR024922 Rubredoxin GO:0005506|GO:0009055 THL1_RS20975 8566cd61d811cd8e6e0207de27f4ae65 53 PRINTS PR00163 Rubredoxin signature 3 19 2.6E-9 T 13-09-2016 IPR024935 Rubredoxin domain GO:0005506 THL1_RS20975 8566cd61d811cd8e6e0207de27f4ae65 53 PRINTS PR00163 Rubredoxin signature 33 49 2.6E-9 T 13-09-2016 IPR024935 Rubredoxin domain GO:0005506 THL1_RS20975 8566cd61d811cd8e6e0207de27f4ae65 53 Gene3D G3DSA:2.20.28.10 1 50 2.2E-25 T 13-09-2016 IPR004039 Rubredoxin-type fold THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 Pfam PF03144 Elongation factor Tu domain 2 191 259 2.1E-8 T 13-09-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 PRINTS PR00315 GTP-binding elongation factor signature 2 15 8.3E-6 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 PRINTS PR00315 GTP-binding elongation factor signature 107 116 8.3E-6 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 PRINTS PR00315 GTP-binding elongation factor signature 70 81 8.3E-6 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 PRINTS PR00315 GTP-binding elongation factor signature 54 64 8.3E-6 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 Gene3D G3DSA:1.10.10.10 506 565 1.1E-11 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 Gene3D G3DSA:2.40.30.10 180 303 7.4E-28 T 13-09-2016 THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 SUPERFAMILY SSF50447 171 262 6.87E-21 T 13-09-2016 IPR009000 Translation protein, beta-barrel domain THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 Pfam PF09107 Elongation factor SelB, winged helix 579 624 1.7E-18 T 13-09-2016 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 SUPERFAMILY SSF46785 504 566 3.08E-12 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 SUPERFAMILY SSF46785 432 503 2.99E-15 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 PANTHER PTHR23115:SF129 1 367 1.8E-124 T 13-09-2016 THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 1 626 4.9E-146 T 13-09-2016 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 Gene3D G3DSA:3.40.50.300 2 179 2.4E-42 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 PANTHER PTHR23115 1 367 1.8E-124 T 13-09-2016 THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 Gene3D G3DSA:1.10.10.10 569 626 1.5E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 Gene3D G3DSA:1.10.10.10 432 498 1.0E-14 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 SUPERFAMILY SSF46785 574 627 6.53E-12 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 Pfam PF09106 Elongation factor SelB, winged helix 443 497 1.9E-14 T 13-09-2016 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 SUPERFAMILY SSF52540 2 163 4.1E-41 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 SUPERFAMILY SSF50465 269 366 3.35E-19 T 13-09-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 26 41 - T 13-09-2016 IPR031157 Tr-type G domain, conserved site THL1_RS25260 da5e35bf79d670949596c99890d56c95 637 Pfam PF00009 Elongation factor Tu GTP binding domain 2 153 2.3E-30 T 13-09-2016 THL1_RS22985 e76e34041dfec12e7a18cab51b3fc14e 330 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 301 1.5E-76 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS22985 e76e34041dfec12e7a18cab51b3fc14e 330 PANTHER PTHR10314 1 321 5.0E-159 T 13-09-2016 THL1_RS22985 e76e34041dfec12e7a18cab51b3fc14e 330 Gene3D G3DSA:3.40.50.1100 43 146 1.3E-38 T 13-09-2016 THL1_RS22985 e76e34041dfec12e7a18cab51b3fc14e 330 Gene3D G3DSA:3.40.50.1100 152 319 3.1E-70 T 13-09-2016 THL1_RS22985 e76e34041dfec12e7a18cab51b3fc14e 330 Gene3D G3DSA:3.40.50.1100 2 42 3.1E-70 T 13-09-2016 THL1_RS22985 e76e34041dfec12e7a18cab51b3fc14e 330 SUPERFAMILY SSF53686 3 321 1.44E-99 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS22985 e76e34041dfec12e7a18cab51b3fc14e 330 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 13-09-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 THL1_RS22985 e76e34041dfec12e7a18cab51b3fc14e 330 PANTHER PTHR10314:SF83 1 321 5.0E-159 T 13-09-2016 THL1_RS05765 3b7ff444844e6281e9864de8ce50c4a6 318 PANTHER PTHR13812 4 315 5.0E-69 T 13-09-2016 THL1_RS05765 3b7ff444844e6281e9864de8ce50c4a6 318 Gene3D G3DSA:3.40.50.720 140 298 7.3E-31 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS05765 3b7ff444844e6281e9864de8ce50c4a6 318 PANTHER PTHR13812:SF19 4 315 5.0E-69 T 13-09-2016 THL1_RS05765 3b7ff444844e6281e9864de8ce50c4a6 318 Gene3D G3DSA:3.30.1780.10 7 139 6.0E-29 T 13-09-2016 IPR023401 Ornithine cyclodeaminase, N-terminal THL1_RS05765 3b7ff444844e6281e9864de8ce50c4a6 318 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 8 312 4.1E-38 T 13-09-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin THL1_RS05765 3b7ff444844e6281e9864de8ce50c4a6 318 SUPERFAMILY SSF51735 6 315 7.57E-69 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS05765 3b7ff444844e6281e9864de8ce50c4a6 318 PIRSF PIRSF001439 1 317 1.8E-53 T 13-09-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin THL1_RS24625 69210f17a47df9dc49ad30a3f4c48003 242 Gene3D G3DSA:1.10.10.10 148 218 6.3E-13 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS24625 69210f17a47df9dc49ad30a3f4c48003 242 PANTHER PTHR24567 1 233 2.1E-71 T 13-09-2016 THL1_RS24625 69210f17a47df9dc49ad30a3f4c48003 242 SUPERFAMILY SSF51206 10 137 5.5E-14 T 13-09-2016 IPR018490 Cyclic nucleotide-binding-like THL1_RS24625 69210f17a47df9dc49ad30a3f4c48003 242 Gene3D G3DSA:2.60.120.10 9 136 1.0E-12 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS24625 69210f17a47df9dc49ad30a3f4c48003 242 SMART SM00419 161 210 3.3E-4 T 13-09-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THL1_RS24625 69210f17a47df9dc49ad30a3f4c48003 242 Pfam PF13545 Crp-like helix-turn-helix domain 150 217 3.7E-15 T 13-09-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THL1_RS24625 69210f17a47df9dc49ad30a3f4c48003 242 PANTHER PTHR24567:SF22 1 233 2.1E-71 T 13-09-2016 THL1_RS24625 69210f17a47df9dc49ad30a3f4c48003 242 SMART SM00100 12 133 5.2E-7 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS24625 69210f17a47df9dc49ad30a3f4c48003 242 SUPERFAMILY SSF46785 147 222 5.93E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS22765 0b5fcb31284a771291c4cc9576f1c12b 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.1E-7 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS22765 0b5fcb31284a771291c4cc9576f1c12b 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.1E-7 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS22765 0b5fcb31284a771291c4cc9576f1c12b 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 4.5E-11 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS22765 0b5fcb31284a771291c4cc9576f1c12b 200 Gene3D G3DSA:1.10.357.10 6 195 6.5E-34 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS22765 0b5fcb31284a771291c4cc9576f1c12b 200 SUPERFAMILY SSF48498 103 192 1.36E-11 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS22765 0b5fcb31284a771291c4cc9576f1c12b 200 SUPERFAMILY SSF46689 6 75 1.7E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS22765 0b5fcb31284a771291c4cc9576f1c12b 200 PANTHER PTHR30055 1 199 1.8E-20 T 13-09-2016 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 Pfam PF00122 E1-E2 ATPase 190 411 1.9E-66 T 13-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 269 283 7.4E-22 T 13-09-2016 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 420 434 7.4E-22 T 13-09-2016 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 565 575 7.4E-22 T 13-09-2016 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 618 637 7.4E-22 T 13-09-2016 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 642 654 7.4E-22 T 13-09-2016 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 PANTHER PTHR24093:SF317 23 715 1.2E-274 T 13-09-2016 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 Gene3D G3DSA:2.70.150.10 169 320 9.2E-27 T 13-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 151 721 2.6E-121 T 13-09-2016 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 PANTHER PTHR24093 23 715 1.2E-274 T 13-09-2016 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 PRINTS PR00941 Cadmium-transporting ATPase signature 204 224 9.4E-10 T 13-09-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 PRINTS PR00941 Cadmium-transporting ATPase signature 304 318 9.4E-10 T 13-09-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 PRINTS PR00941 Cadmium-transporting ATPase signature 285 301 9.4E-10 T 13-09-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 SUPERFAMILY SSF81665 169 223 5.1E-13 T 13-09-2016 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 SUPERFAMILY SSF81665 320 407 5.1E-13 T 13-09-2016 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 SUPERFAMILY SSF81653 222 319 4.71E-25 T 13-09-2016 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 422 428 - T 13-09-2016 IPR018303 P-type ATPase, phosphorylation site THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 Pfam PF00702 haloacid dehalogenase-like hydrolase 418 632 7.4E-40 T 13-09-2016 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 SUPERFAMILY SSF56784 476 718 2.65E-52 T 13-09-2016 IPR023214 HAD-like domain THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 SUPERFAMILY SSF56784 419 438 2.65E-52 T 13-09-2016 IPR023214 HAD-like domain THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 SUPERFAMILY SSF55008 28 96 8.13E-10 T 13-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 192 451 1.5E-37 T 13-09-2016 IPR001757 P-type ATPase GO:0016021 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 518 696 1.0E-36 T 13-09-2016 IPR001757 P-type ATPase GO:0016021 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 Gene3D G3DSA:3.40.50.1000 546 687 1.4E-41 T 13-09-2016 IPR023214 HAD-like domain THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 Gene3D G3DSA:3.40.50.1000 393 436 1.4E-41 T 13-09-2016 IPR023214 HAD-like domain THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 Gene3D G3DSA:3.30.70.100 33 96 9.6E-6 T 13-09-2016 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 169 721 1.1E-174 T 13-09-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 Gene3D G3DSA:3.40.1110.10 449 545 1.4E-17 T 13-09-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 THL1_RS22840 be00c9a95e5b47d72bf6e9a2ce809776 727 Pfam PF00403 Heavy-metal-associated domain 34 89 1.0E-4 T 13-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THL1_RS17420 77b5d59b0966036cc09cf63113a73215 400 PIRSF PIRSF000429 1 400 3.5E-128 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS17420 77b5d59b0966036cc09cf63113a73215 400 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 13-09-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 THL1_RS17420 77b5d59b0966036cc09cf63113a73215 400 PANTHER PTHR18919:SF91 1 400 5.7E-206 T 13-09-2016 THL1_RS17420 77b5d59b0966036cc09cf63113a73215 400 SUPERFAMILY SSF53901 3 273 1.51E-71 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17420 77b5d59b0966036cc09cf63113a73215 400 Gene3D G3DSA:3.40.47.10 153 197 2.6E-58 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17420 77b5d59b0966036cc09cf63113a73215 400 Gene3D G3DSA:3.40.47.10 281 398 2.6E-58 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17420 77b5d59b0966036cc09cf63113a73215 400 PANTHER PTHR18919 1 400 5.7E-206 T 13-09-2016 THL1_RS17420 77b5d59b0966036cc09cf63113a73215 400 Pfam PF02803 Thiolase, C-terminal domain 275 398 3.9E-45 T 13-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THL1_RS17420 77b5d59b0966036cc09cf63113a73215 400 Gene3D G3DSA:3.40.47.10 3 123 2.8E-62 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17420 77b5d59b0966036cc09cf63113a73215 400 Gene3D G3DSA:3.40.47.10 198 280 2.8E-62 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17420 77b5d59b0966036cc09cf63113a73215 400 ProSitePatterns PS00737 Thiolases signature 2. 345 361 - T 13-09-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 THL1_RS17420 77b5d59b0966036cc09cf63113a73215 400 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 5 397 1.4E-131 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS17420 77b5d59b0966036cc09cf63113a73215 400 Pfam PF00108 Thiolase, N-terminal domain 4 266 8.3E-66 T 13-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THL1_RS17420 77b5d59b0966036cc09cf63113a73215 400 ProSitePatterns PS00099 Thiolases active site. 380 393 - T 13-09-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 THL1_RS17420 77b5d59b0966036cc09cf63113a73215 400 SUPERFAMILY SSF53901 275 398 4.94E-45 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS26780 aa6d2db4c7a20db456cd60c5495221ce 90 Gene3D G3DSA:1.10.3880.10 1 89 3.1E-40 T 13-09-2016 THL1_RS26780 aa6d2db4c7a20db456cd60c5495221ce 90 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 74 7.0E-37 T 13-09-2016 IPR007457 Fe(II) trafficking protein YggX GO:0005506 THL1_RS26780 aa6d2db4c7a20db456cd60c5495221ce 90 PIRSF PIRSF029827 1 90 5.7E-40 T 13-09-2016 IPR007457 Fe(II) trafficking protein YggX GO:0005506 THL1_RS26780 aa6d2db4c7a20db456cd60c5495221ce 90 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 26.876 T 13-09-2016 IPR007457 Fe(II) trafficking protein YggX GO:0005506 THL1_RS26780 aa6d2db4c7a20db456cd60c5495221ce 90 SUPERFAMILY SSF111148 1 89 2.22E-39 T 13-09-2016 IPR007457 Fe(II) trafficking protein YggX GO:0005506 THL1_RS26780 aa6d2db4c7a20db456cd60c5495221ce 90 PANTHER PTHR36965:SF1 2 90 1.2E-48 T 13-09-2016 THL1_RS26780 aa6d2db4c7a20db456cd60c5495221ce 90 PANTHER PTHR36965 2 90 1.2E-48 T 13-09-2016 THL1_RS26780 aa6d2db4c7a20db456cd60c5495221ce 90 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 3.6E-40 T 13-09-2016 IPR007457 Fe(II) trafficking protein YggX GO:0005506 THL1_RS14490 23b4931fd1a19f90b495c7f16be1fb2e 328 PANTHER PTHR10443 1 246 5.7E-66 T 13-09-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 THL1_RS14490 23b4931fd1a19f90b495c7f16be1fb2e 328 PANTHER PTHR10443 276 320 5.7E-66 T 13-09-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 THL1_RS14490 23b4931fd1a19f90b495c7f16be1fb2e 328 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 16 321 1.2E-87 T 13-09-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 THL1_RS14490 23b4931fd1a19f90b495c7f16be1fb2e 328 PANTHER PTHR10443:SF24 276 320 5.7E-66 T 13-09-2016 THL1_RS14490 23b4931fd1a19f90b495c7f16be1fb2e 328 PANTHER PTHR10443:SF24 1 246 5.7E-66 T 13-09-2016 THL1_RS14490 23b4931fd1a19f90b495c7f16be1fb2e 328 Gene3D G3DSA:3.20.20.140 1 321 2.4E-84 T 13-09-2016 THL1_RS14490 23b4931fd1a19f90b495c7f16be1fb2e 328 SUPERFAMILY SSF51556 6 245 4.08E-86 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS14490 23b4931fd1a19f90b495c7f16be1fb2e 328 SUPERFAMILY SSF51556 277 323 4.08E-86 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 PANTHER PTHR11709:SF33 486 637 3.9E-118 T 13-09-2016 THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 ProSitePatterns PS00080 Multicopper oxidases signature 2. 618 629 - T 13-09-2016 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 5 32 1.1E-5 T 13-09-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 Pfam PF07732 Multicopper oxidase 53 163 9.5E-40 T 13-09-2016 IPR011707 Multicopper oxidase, type 3 GO:0005507 THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 Gene3D G3DSA:2.60.40.420 513 636 4.4E-34 T 13-09-2016 IPR008972 Cupredoxin THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 SUPERFAMILY SSF49503 484 635 4.23E-37 T 13-09-2016 IPR008972 Cupredoxin THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 Gene3D G3DSA:2.60.40.420 41 168 1.2E-31 T 13-09-2016 IPR008972 Cupredoxin THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 PANTHER PTHR11709:SF33 47 206 3.9E-118 T 13-09-2016 THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 PANTHER PTHR11709 486 637 3.9E-118 T 13-09-2016 THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 PANTHER PTHR11709 47 206 3.9E-118 T 13-09-2016 THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 ProSitePatterns PS00079 Multicopper oxidases signature 1. 613 633 - T 13-09-2016 IPR033138 Multicopper oxidases, conserved site THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 PANTHER PTHR11709:SF33 247 364 3.9E-118 T 13-09-2016 THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 Gene3D G3DSA:2.60.40.420 169 374 2.4E-52 T 13-09-2016 IPR008972 Cupredoxin THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 Pfam PF07731 Multicopper oxidase 520 636 1.0E-25 T 13-09-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 SUPERFAMILY SSF49503 167 379 5.95E-57 T 13-09-2016 IPR008972 Cupredoxin THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 SUPERFAMILY SSF49503 46 193 5.01E-39 T 13-09-2016 IPR008972 Cupredoxin THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 Pfam PF00394 Multicopper oxidase 172 350 3.8E-37 T 13-09-2016 IPR001117 Multicopper oxidase, type 1 GO:0016491|GO:0055114 THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 TIGRFAM TIGR01480 copper_res_A: copper-resistance protein, CopA family 4 420 3.0E-205 T 13-09-2016 IPR006376 Copper-resistance protein CopA GO:0005507|GO:0042597 THL1_RS12790 56a5f37e97434ffb24fc68fd80fd3541 637 PANTHER PTHR11709 247 364 3.9E-118 T 13-09-2016 THL1_RS08630 03935a80ad9ada1ba2f2388deecc1e10 610 SUPERFAMILY SSF52540 351 602 1.58E-86 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08630 03935a80ad9ada1ba2f2388deecc1e10 610 ProSitePatterns PS00211 ABC transporters family signature. 504 518 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS08630 03935a80ad9ada1ba2f2388deecc1e10 610 Gene3D G3DSA:1.20.1560.10 31 334 5.8E-34 T 13-09-2016 THL1_RS08630 03935a80ad9ada1ba2f2388deecc1e10 610 SUPERFAMILY SSF90123 22 343 1.57E-49 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS08630 03935a80ad9ada1ba2f2388deecc1e10 610 Pfam PF00664 ABC transporter transmembrane region 44 305 1.9E-15 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS08630 03935a80ad9ada1ba2f2388deecc1e10 610 SMART SM00382 387 578 2.9E-21 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS08630 03935a80ad9ada1ba2f2388deecc1e10 610 Gene3D G3DSA:3.40.50.300 362 597 3.8E-78 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08630 03935a80ad9ada1ba2f2388deecc1e10 610 PANTHER PTHR24221 3 610 0.0 T 13-09-2016 THL1_RS08630 03935a80ad9ada1ba2f2388deecc1e10 610 Pfam PF00005 ABC transporter 380 532 4.2E-34 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS08630 03935a80ad9ada1ba2f2388deecc1e10 610 PANTHER PTHR24221:SF203 3 610 0.0 T 13-09-2016 THL1_RS18505 bd3f6ef736dae987e581093f34b9c81c 260 PANTHER PTHR10060 1 258 2.9E-127 T 13-09-2016 IPR001130 TatD family GO:0016788 THL1_RS18505 bd3f6ef736dae987e581093f34b9c81c 260 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 191 207 - T 13-09-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 THL1_RS18505 bd3f6ef736dae987e581093f34b9c81c 260 Pfam PF01026 TatD related DNase 3 254 5.9E-79 T 13-09-2016 IPR001130 TatD family GO:0016788 THL1_RS18505 bd3f6ef736dae987e581093f34b9c81c 260 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 254 1.5E-84 T 13-09-2016 IPR015991 Uncharacterised deoxyribonuclease TatD-type GO:0004536 THL1_RS18505 bd3f6ef736dae987e581093f34b9c81c 260 PIRSF PIRSF005902 1 258 1.6E-77 T 13-09-2016 IPR001130 TatD family GO:0016788 THL1_RS18505 bd3f6ef736dae987e581093f34b9c81c 260 PANTHER PTHR10060:SF20 1 258 2.9E-127 T 13-09-2016 THL1_RS18505 bd3f6ef736dae987e581093f34b9c81c 260 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 127 137 - T 13-09-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 THL1_RS18505 bd3f6ef736dae987e581093f34b9c81c 260 Gene3D G3DSA:3.20.20.140 1 256 1.1E-84 T 13-09-2016 THL1_RS18505 bd3f6ef736dae987e581093f34b9c81c 260 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 13-09-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 THL1_RS18505 bd3f6ef736dae987e581093f34b9c81c 260 SUPERFAMILY SSF51556 2 256 1.51E-85 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS00655 f18efcb3cd1d938c1119bd3c9664efc4 307 Pfam PF03797 Autotransporter beta-domain 66 290 5.8E-21 T 13-09-2016 IPR005546 Autotransporter beta-domain THL1_RS00655 f18efcb3cd1d938c1119bd3c9664efc4 307 Gene3D G3DSA:2.40.128.130 36 307 6.0E-28 T 13-09-2016 IPR005546 Autotransporter beta-domain THL1_RS00655 f18efcb3cd1d938c1119bd3c9664efc4 307 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 28 307 1.7E-19 T 13-09-2016 IPR006315 Outer membrane autotransporter barrel GO:0019867 THL1_RS00655 f18efcb3cd1d938c1119bd3c9664efc4 307 SMART SM00869 67 297 5.8E-26 T 13-09-2016 IPR005546 Autotransporter beta-domain THL1_RS00655 f18efcb3cd1d938c1119bd3c9664efc4 307 SUPERFAMILY SSF103515 30 307 2.09E-39 T 13-09-2016 IPR005546 Autotransporter beta-domain THL1_RS18000 a46d9a8b5f8c649c4145b3b66b93df0b 436 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 157 237 1.7E-13 T 13-09-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 THL1_RS18000 a46d9a8b5f8c649c4145b3b66b93df0b 436 Gene3D G3DSA:1.10.3120.10 214 388 1.0E-61 T 13-09-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 THL1_RS18000 a46d9a8b5f8c649c4145b3b66b93df0b 436 SUPERFAMILY SSF102735 1 130 1.57E-37 T 13-09-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 THL1_RS18000 a46d9a8b5f8c649c4145b3b66b93df0b 436 PANTHER PTHR30560:SF3 1 429 5.9E-129 T 13-09-2016 THL1_RS18000 a46d9a8b5f8c649c4145b3b66b93df0b 436 PANTHER PTHR30560 1 429 5.9E-129 T 13-09-2016 THL1_RS18000 a46d9a8b5f8c649c4145b3b66b93df0b 436 Gene3D G3DSA:3.10.50.40 156 213 4.0E-10 T 13-09-2016 THL1_RS18000 a46d9a8b5f8c649c4145b3b66b93df0b 436 Hamap MF_00303 Trigger factor [tig]. 1 417 21.328 T 13-09-2016 IPR005215 Trigger factor GO:0015031 THL1_RS18000 a46d9a8b5f8c649c4145b3b66b93df0b 436 TIGRFAM TIGR00115 tig: trigger factor 11 410 6.0E-141 T 13-09-2016 IPR005215 Trigger factor GO:0015031 THL1_RS18000 a46d9a8b5f8c649c4145b3b66b93df0b 436 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 263 411 6.4E-37 T 13-09-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 THL1_RS18000 a46d9a8b5f8c649c4145b3b66b93df0b 436 SUPERFAMILY SSF54534 89 240 1.0E-34 T 13-09-2016 THL1_RS18000 a46d9a8b5f8c649c4145b3b66b93df0b 436 SUPERFAMILY SSF109998 248 428 6.54E-49 T 13-09-2016 IPR027304 Trigger factor/SurA domain THL1_RS18000 a46d9a8b5f8c649c4145b3b66b93df0b 436 PIRSF PIRSF003095 1 432 2.5E-126 T 13-09-2016 IPR005215 Trigger factor GO:0015031 THL1_RS18000 a46d9a8b5f8c649c4145b3b66b93df0b 436 Gene3D G3DSA:3.30.70.1050 1 117 8.6E-38 T 13-09-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 THL1_RS18000 a46d9a8b5f8c649c4145b3b66b93df0b 436 Pfam PF05697 Bacterial trigger factor protein (TF) 1 142 6.1E-40 T 13-09-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 THL1_RS01030 649fa2285e906e80356ac6b2f714a2cf 377 Gene3D G3DSA:1.10.3290.10 39 300 3.1E-65 T 13-09-2016 IPR003812 Fido domain THL1_RS01030 649fa2285e906e80356ac6b2f714a2cf 377 Pfam PF02661 Fic/DOC family 124 229 1.8E-23 T 13-09-2016 IPR003812 Fido domain THL1_RS01030 649fa2285e906e80356ac6b2f714a2cf 377 SUPERFAMILY SSF140931 102 295 9.94E-50 T 13-09-2016 IPR003812 Fido domain THL1_RS01030 649fa2285e906e80356ac6b2f714a2cf 377 PANTHER PTHR13504 32 375 5.5E-80 T 13-09-2016 THL1_RS01030 649fa2285e906e80356ac6b2f714a2cf 377 PIRSF PIRSF038925 12 377 3.4E-112 T 13-09-2016 IPR026287 Adenosine monophosphate-protein transferase THL1_RS01030 649fa2285e906e80356ac6b2f714a2cf 377 SUPERFAMILY SSF46785 309 366 5.36E-6 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS01030 649fa2285e906e80356ac6b2f714a2cf 377 PANTHER PTHR13504:SF32 32 375 5.5E-80 T 13-09-2016 THL1_RS01030 649fa2285e906e80356ac6b2f714a2cf 377 Gene3D G3DSA:1.10.10.10 314 356 3.7E-6 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS01030 649fa2285e906e80356ac6b2f714a2cf 377 Pfam PF13784 Fic/DOC family N-terminal 39 118 7.4E-24 T 13-09-2016 IPR025758 Fic/DOC N-terminal THL1_RS18700 df7344532b80a19e06c1b979d4af4c25 593 TIGRFAM TIGR02204 MsbA_rel: ABC transporter, permease/ATP-binding protein 9 584 7.9E-272 T 13-09-2016 IPR011918 ABC transporter, ATP-binding/permease protein THL1_RS18700 df7344532b80a19e06c1b979d4af4c25 593 Pfam PF00005 ABC transporter 364 513 1.3E-31 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS18700 df7344532b80a19e06c1b979d4af4c25 593 PANTHER PTHR24221 18 592 3.8E-227 T 13-09-2016 THL1_RS18700 df7344532b80a19e06c1b979d4af4c25 593 Pfam PF00664 ABC transporter transmembrane region 29 295 3.0E-50 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS18700 df7344532b80a19e06c1b979d4af4c25 593 SMART SM00382 373 559 2.4E-17 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS18700 df7344532b80a19e06c1b979d4af4c25 593 Gene3D G3DSA:1.20.1560.10 18 323 1.6E-74 T 13-09-2016 THL1_RS18700 df7344532b80a19e06c1b979d4af4c25 593 SUPERFAMILY SSF90123 17 323 1.7E-71 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS18700 df7344532b80a19e06c1b979d4af4c25 593 SUPERFAMILY SSF52540 338 584 1.43E-88 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18700 df7344532b80a19e06c1b979d4af4c25 593 ProSitePatterns PS00211 ABC transporters family signature. 485 499 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS18700 df7344532b80a19e06c1b979d4af4c25 593 Gene3D G3DSA:3.40.50.300 346 575 3.9E-82 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS20965 97f933501181c0e4721352e8e3726167 208 Pfam PF13305 WHG domain 90 174 5.1E-11 T 13-09-2016 IPR025996 WHG domain THL1_RS20965 97f933501181c0e4721352e8e3726167 208 SUPERFAMILY SSF46689 12 74 3.49E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS20965 97f933501181c0e4721352e8e3726167 208 Gene3D G3DSA:1.10.357.10 12 192 1.2E-32 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS20965 97f933501181c0e4721352e8e3726167 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 7.1E-11 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20965 97f933501181c0e4721352e8e3726167 208 SUPERFAMILY SSF48498 87 191 4.82E-18 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS20965 97f933501181c0e4721352e8e3726167 208 PANTHER PTHR30055 2 172 6.7E-22 T 13-09-2016 THL1_RS20965 97f933501181c0e4721352e8e3726167 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.8E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20965 97f933501181c0e4721352e8e3726167 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 3.8E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 66 740 1.1E-182 T 13-09-2016 THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 Pfam PF00912 Transglycosylase 56 230 1.7E-63 T 13-09-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 PANTHER PTHR32282:SF5 418 609 7.1E-267 T 13-09-2016 THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 Gene3D G3DSA:2.40.50.140 343 418 1.2E-19 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 PANTHER PTHR32282 1 311 7.1E-267 T 13-09-2016 THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 PANTHER PTHR32282 646 792 7.1E-267 T 13-09-2016 THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 PANTHER PTHR32282 418 609 7.1E-267 T 13-09-2016 THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 Gene3D G3DSA:3.40.710.10 647 789 2.9E-134 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 Gene3D G3DSA:3.40.710.10 234 314 2.9E-134 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 Gene3D G3DSA:3.40.710.10 419 608 2.9E-134 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 Pfam PF17092 Penicillin-binding protein OB-like domain 317 422 1.8E-23 T 13-09-2016 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00230+2.4.2.-|KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00514+2.4.2.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.-|UniPathway: UPA00219 THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 Gene3D G3DSA:1.10.3810.10 56 233 3.8E-72 T 13-09-2016 THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 SUPERFAMILY SSF56601 646 790 2.41E-129 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 SUPERFAMILY SSF56601 419 607 2.41E-129 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 SUPERFAMILY SSF56601 212 234 2.41E-129 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 SUPERFAMILY SSF56601 263 314 2.41E-129 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 PANTHER PTHR32282:SF5 1 311 7.1E-267 T 13-09-2016 THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 PANTHER PTHR32282:SF5 646 792 7.1E-267 T 13-09-2016 THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 Pfam PF00905 Penicillin binding protein transpeptidase domain 426 734 1.5E-34 T 13-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THL1_RS26325 74eb9fe5a3f885e58af82586658f0cac 812 SUPERFAMILY SSF53955 44 255 1.15E-76 T 13-09-2016 IPR023346 Lysozyme-like domain THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 Gene3D G3DSA:1.20.210.10 14 528 4.8E-216 T 13-09-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 253 307 - T 13-09-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 33 475 3.3E-152 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 25 527 1.1E-212 T 13-09-2016 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 PANTHER PTHR10422:SF27 9 529 0.0 T 13-09-2016 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 PRINTS PR01165 Cytochrome c oxidase subunit I signature 434 455 6.9E-123 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 PRINTS PR01165 Cytochrome c oxidase subunit I signature 141 153 6.9E-123 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 PRINTS PR01165 Cytochrome c oxidase subunit I signature 384 403 6.9E-123 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 PRINTS PR01165 Cytochrome c oxidase subunit I signature 171 189 6.9E-123 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 PRINTS PR01165 Cytochrome c oxidase subunit I signature 321 342 6.9E-123 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 PRINTS PR01165 Cytochrome c oxidase subunit I signature 24 49 6.9E-123 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 PRINTS PR01165 Cytochrome c oxidase subunit I signature 297 312 6.9E-123 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 PRINTS PR01165 Cytochrome c oxidase subunit I signature 200 219 6.9E-123 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 PRINTS PR01165 Cytochrome c oxidase subunit I signature 251 272 6.9E-123 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 PRINTS PR01165 Cytochrome c oxidase subunit I signature 71 94 6.9E-123 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 PRINTS PR01165 Cytochrome c oxidase subunit I signature 98 122 6.9E-123 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 PRINTS PR01165 Cytochrome c oxidase subunit I signature 356 374 6.9E-123 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 PANTHER PTHR10422 9 529 0.0 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS00255 2b2b1a5309529e371127dab5ded80a54 529 SUPERFAMILY SSF81442 22 527 1.44E-192 T 13-09-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS21540 22410f98848c0972210de9c45f6ebbb1 497 SMART SM00267 318 489 1.6E-66 T 13-09-2016 IPR000160 GGDEF domain THL1_RS21540 22410f98848c0972210de9c45f6ebbb1 497 Pfam PF00990 Diguanylate cyclase, GGDEF domain 329 484 4.3E-50 T 13-09-2016 IPR000160 GGDEF domain THL1_RS21540 22410f98848c0972210de9c45f6ebbb1 497 PANTHER PTHR10799:SF750 292 486 1.5E-28 T 13-09-2016 THL1_RS21540 22410f98848c0972210de9c45f6ebbb1 497 PANTHER PTHR10799 292 486 1.5E-28 T 13-09-2016 THL1_RS21540 22410f98848c0972210de9c45f6ebbb1 497 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 327 488 6.4E-50 T 13-09-2016 IPR000160 GGDEF domain THL1_RS21540 22410f98848c0972210de9c45f6ebbb1 497 Gene3D G3DSA:3.30.450.20 91 172 2.4E-5 T 13-09-2016 THL1_RS21540 22410f98848c0972210de9c45f6ebbb1 497 Pfam PF02743 Cache domain 74 281 3.6E-18 T 13-09-2016 IPR033479 Double Cache domain 1 THL1_RS21540 22410f98848c0972210de9c45f6ebbb1 497 SUPERFAMILY SSF55073 334 488 6.75E-50 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS21540 22410f98848c0972210de9c45f6ebbb1 497 Gene3D G3DSA:3.30.450.20 173 293 1.0E-8 T 13-09-2016 THL1_RS21540 22410f98848c0972210de9c45f6ebbb1 497 Gene3D G3DSA:3.30.70.270 331 488 5.5E-56 T 13-09-2016 THL1_RS11510 75e7f1309858bc2c41c117001e4379b1 317 SUPERFAMILY SSF46785 8 115 5.9E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11510 75e7f1309858bc2c41c117001e4379b1 317 Gene3D G3DSA:3.40.190.10 182 264 3.9E-18 T 13-09-2016 THL1_RS11510 75e7f1309858bc2c41c117001e4379b1 317 Pfam PF03466 LysR substrate binding domain 91 301 1.5E-33 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS11510 75e7f1309858bc2c41c117001e4379b1 317 Gene3D G3DSA:1.10.10.10 8 88 2.6E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11510 75e7f1309858bc2c41c117001e4379b1 317 Gene3D G3DSA:3.40.190.10 96 181 1.1E-18 T 13-09-2016 THL1_RS11510 75e7f1309858bc2c41c117001e4379b1 317 PANTHER PTHR30126 7 315 1.2E-120 T 13-09-2016 THL1_RS11510 75e7f1309858bc2c41c117001e4379b1 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 2.2E-17 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS11510 75e7f1309858bc2c41c117001e4379b1 317 SUPERFAMILY SSF53850 93 304 2.71E-35 T 13-09-2016 THL1_RS11510 75e7f1309858bc2c41c117001e4379b1 317 PANTHER PTHR30126:SF12 7 315 1.2E-120 T 13-09-2016 THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 PANTHER PTHR30050 1 102 6.5E-236 T 13-09-2016 THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 PANTHER PTHR30050 150 487 6.5E-236 T 13-09-2016 THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 SMART SM00382 184 389 5.0E-7 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 3 486 34.182 T 13-09-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 Gene3D G3DSA:1.10.8.60 318 385 9.4E-30 T 13-09-2016 THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 Gene3D G3DSA:3.40.50.300 146 316 2.3E-62 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 Pfam PF00308 Bacterial dnaA protein 152 369 7.0E-101 T 13-09-2016 IPR013317 Chromosomal replication initiator protein DnaA THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 Gene3D G3DSA:1.10.1750.10 386 486 8.7E-41 T 13-09-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 6 485 6.4E-189 T 13-09-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 Pfam PF11638 DnaA N-terminal domain 4 63 5.9E-21 T 13-09-2016 IPR024633 DnaA N-terminal domain THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 ProSitePatterns PS01008 DnaA protein signature. 445 464 - T 13-09-2016 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 396 464 1.8E-31 T 13-09-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 PANTHER PTHR30050:SF2 1 102 6.5E-236 T 13-09-2016 THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 PANTHER PTHR30050:SF2 150 487 6.5E-236 T 13-09-2016 THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 SUPERFAMILY SSF48295 383 485 2.2E-36 T 13-09-2016 IPR010921 Trp repressor/replication initiator GO:0043565 THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 SMART SM00760 395 464 4.6E-42 T 13-09-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 249 263 2.6E-53 T 13-09-2016 IPR020591 Chromosomal replication control, initiator DnaA-like THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 283 310 2.6E-53 T 13-09-2016 IPR020591 Chromosomal replication control, initiator DnaA-like THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 217 231 2.6E-53 T 13-09-2016 IPR020591 Chromosomal replication control, initiator DnaA-like THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 185 205 2.6E-53 T 13-09-2016 IPR020591 Chromosomal replication control, initiator DnaA-like THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 445 464 2.6E-53 T 13-09-2016 IPR020591 Chromosomal replication control, initiator DnaA-like THL1_RS00005 a3b2703b313b6719ebc18ffeef498da1 487 SUPERFAMILY SSF52540 153 363 3.38E-44 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00905 2cb6f3ed9b06854bd2ab86f4fe90e9c5 443 Pfam PF03573 outer membrane porin, OprD family 23 441 2.9E-143 T 13-09-2016 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 THL1_RS00905 2cb6f3ed9b06854bd2ab86f4fe90e9c5 443 PANTHER PTHR34596 6 269 2.4E-144 T 13-09-2016 THL1_RS00905 2cb6f3ed9b06854bd2ab86f4fe90e9c5 443 PANTHER PTHR34596 291 443 2.4E-144 T 13-09-2016 THL1_RS00905 2cb6f3ed9b06854bd2ab86f4fe90e9c5 443 Gene3D G3DSA:2.40.160.10 27 443 1.4E-145 T 13-09-2016 IPR023614 Porin domain THL1_RS18445 6ff5501ec58a7694ac436a46e34cbebd 270 Pfam PF14346 Domain of unknown function (DUF4398) 16 116 4.2E-23 T 13-09-2016 IPR025511 Domain of unknown function DUF4398 THL1_RS18445 6ff5501ec58a7694ac436a46e34cbebd 270 PRINTS PR01021 OMPA domain signature 189 204 4.6E-10 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS18445 6ff5501ec58a7694ac436a46e34cbebd 270 PRINTS PR01021 OMPA domain signature 159 181 4.6E-10 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS18445 6ff5501ec58a7694ac436a46e34cbebd 270 PRINTS PR01021 OMPA domain signature 204 220 4.6E-10 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS18445 6ff5501ec58a7694ac436a46e34cbebd 270 Pfam PF00691 OmpA family 158 253 5.8E-24 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS18445 6ff5501ec58a7694ac436a46e34cbebd 270 PANTHER PTHR30128 145 267 3.7E-40 T 13-09-2016 THL1_RS18445 6ff5501ec58a7694ac436a46e34cbebd 270 SUPERFAMILY SSF103088 141 258 9.42E-36 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS18445 6ff5501ec58a7694ac436a46e34cbebd 270 Gene3D G3DSA:3.30.1330.60 149 259 3.4E-38 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 PANTHER PTHR11405 1 298 1.5E-139 T 13-09-2016 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 Gene3D G3DSA:3.40.50.1370 142 286 5.9E-57 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 2.1E-26 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 264 287 2.1E-26 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 252 261 2.1E-26 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 131 142 2.1E-26 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 PANTHER PTHR11405:SF1 1 298 1.5E-139 T 13-09-2016 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 SUPERFAMILY SSF53671 3 300 1.01E-102 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 150 297 2.2E-49 T 13-09-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 3 300 78.845 T 13-09-2016 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 47 61 2.8E-28 T 13-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 80 93 2.8E-28 T 13-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 120 134 2.8E-28 T 13-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 278 289 2.8E-28 T 13-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 PRINTS PR00102 Ornithine carbamoyltransferase signature 216 226 2.8E-28 T 13-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 4 299 6.0E-115 T 13-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 Gene3D G3DSA:3.40.50.1370 1 141 3.2E-53 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS21620 1082d6503388f79b6ee22f4e6ae7d4f2 305 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 4 144 9.8E-47 T 13-09-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 THL1_RS10110 67a2061e3322126fa58c08fce3002fac 428 Gene3D G3DSA:3.90.190.20 298 423 3.4E-33 T 13-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 THL1_RS10110 67a2061e3322126fa58c08fce3002fac 428 PANTHER PTHR11136:SF0 9 428 7.5E-116 T 13-09-2016 THL1_RS10110 67a2061e3322126fa58c08fce3002fac 428 PIRSF PIRSF001563 1 426 2.6E-100 T 13-09-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 THL1_RS10110 67a2061e3322126fa58c08fce3002fac 428 SUPERFAMILY SSF53623 3 283 1.01E-88 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS10110 67a2061e3322126fa58c08fce3002fac 428 PANTHER PTHR11136 9 428 7.5E-116 T 13-09-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 THL1_RS10110 67a2061e3322126fa58c08fce3002fac 428 Gene3D G3DSA:3.40.1190.10 5 282 2.0E-88 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS10110 67a2061e3322126fa58c08fce3002fac 428 SUPERFAMILY SSF53244 286 422 1.83E-27 T 13-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 THL1_RS10110 67a2061e3322126fa58c08fce3002fac 428 TIGRFAM TIGR01499 folC: bifunctional protein FolC 25 420 1.6E-95 T 13-09-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 THL1_RS10110 67a2061e3322126fa58c08fce3002fac 428 Pfam PF08245 Mur ligase middle domain 47 187 6.5E-12 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS12765 cd4aeac977e6ffe190af4e6fdbcfec0b 119 SUPERFAMILY SSF46458 18 111 7.91E-19 T 13-09-2016 IPR009050 Globin-like THL1_RS12765 cd4aeac977e6ffe190af4e6fdbcfec0b 119 Gene3D G3DSA:1.10.490.10 14 113 5.4E-19 T 13-09-2016 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 THL1_RS12765 cd4aeac977e6ffe190af4e6fdbcfec0b 119 Pfam PF01152 Bacterial-like globin 24 94 8.0E-14 T 13-09-2016 IPR001486 Truncated hemoglobin GO:0019825 THL1_RS00920 29dd4c35156f2e5a7bf3c6afbcb7188d 387 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 4 379 70.784 T 13-09-2016 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 THL1_RS00920 29dd4c35156f2e5a7bf3c6afbcb7188d 387 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 4 349 1.0E-191 T 13-09-2016 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 THL1_RS00920 29dd4c35156f2e5a7bf3c6afbcb7188d 387 Gene3D G3DSA:3.20.20.30 287 350 8.6E-102 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS00920 29dd4c35156f2e5a7bf3c6afbcb7188d 387 Gene3D G3DSA:3.20.20.30 3 253 8.6E-102 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS00920 29dd4c35156f2e5a7bf3c6afbcb7188d 387 PANTHER PTHR30011 1 377 1.5E-216 T 13-09-2016 THL1_RS00920 29dd4c35156f2e5a7bf3c6afbcb7188d 387 PANTHER PTHR30011:SF1 1 377 1.5E-216 T 13-09-2016 THL1_RS00920 29dd4c35156f2e5a7bf3c6afbcb7188d 387 Pfam PF00296 Luciferase-like monooxygenase 4 325 8.7E-86 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS00920 29dd4c35156f2e5a7bf3c6afbcb7188d 387 SUPERFAMILY SSF51679 3 349 1.44E-96 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS09360 1f6db92fb153a154c7c5633c2e5b3845 133 PANTHER PTHR35813:SF1 2 132 1.1E-45 T 13-09-2016 THL1_RS09360 1f6db92fb153a154c7c5633c2e5b3845 133 PIRSF PIRSF016789 14 133 9.5E-37 T 13-09-2016 IPR007401 Protein of unknown function DUF454 THL1_RS09360 1f6db92fb153a154c7c5633c2e5b3845 133 Pfam PF04304 Protein of unknown function (DUF454) 15 129 8.8E-40 T 13-09-2016 IPR007401 Protein of unknown function DUF454 THL1_RS09360 1f6db92fb153a154c7c5633c2e5b3845 133 PANTHER PTHR35813 2 132 1.1E-45 T 13-09-2016 THL1_RS20165 291081865edf1727c5c4b35fa52423cc 297 PANTHER PTHR30579 1 290 3.7E-98 T 13-09-2016 THL1_RS20165 291081865edf1727c5c4b35fa52423cc 297 Gene3D G3DSA:3.40.190.10 96 174 2.3E-16 T 13-09-2016 THL1_RS20165 291081865edf1727c5c4b35fa52423cc 297 Pfam PF03466 LysR substrate binding domain 92 285 8.7E-32 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS20165 291081865edf1727c5c4b35fa52423cc 297 Gene3D G3DSA:3.40.190.10 175 244 9.5E-11 T 13-09-2016 THL1_RS20165 291081865edf1727c5c4b35fa52423cc 297 SUPERFAMILY SSF53850 94 287 2.17E-32 T 13-09-2016 THL1_RS20165 291081865edf1727c5c4b35fa52423cc 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 4.1E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS20165 291081865edf1727c5c4b35fa52423cc 297 PANTHER PTHR30579:SF3 1 290 3.7E-98 T 13-09-2016 THL1_RS20165 291081865edf1727c5c4b35fa52423cc 297 Gene3D G3DSA:1.10.10.10 6 84 2.5E-12 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20165 291081865edf1727c5c4b35fa52423cc 297 SUPERFAMILY SSF46785 5 116 4.99E-12 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19060 afcc8756e3b17fd50319e67bf28a283b 370 Gene3D G3DSA:3.40.800.20 4 361 3.3E-96 T 13-09-2016 IPR023801 Histone deacetylase domain THL1_RS19060 afcc8756e3b17fd50319e67bf28a283b 370 PRINTS PR01270 Histone deacetylase superfamily signature 174 189 1.4E-15 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS19060 afcc8756e3b17fd50319e67bf28a283b 370 PRINTS PR01270 Histone deacetylase superfamily signature 140 163 1.4E-15 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS19060 afcc8756e3b17fd50319e67bf28a283b 370 PRINTS PR01270 Histone deacetylase superfamily signature 259 269 1.4E-15 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS19060 afcc8756e3b17fd50319e67bf28a283b 370 Pfam PF00850 Histone deacetylase domain 43 328 2.4E-78 T 13-09-2016 IPR023801 Histone deacetylase domain THL1_RS19060 afcc8756e3b17fd50319e67bf28a283b 370 SUPERFAMILY SSF52768 2 344 2.88E-104 T 13-09-2016 THL1_RS19060 afcc8756e3b17fd50319e67bf28a283b 370 PANTHER PTHR10625 32 364 1.6E-97 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS19060 afcc8756e3b17fd50319e67bf28a283b 370 PANTHER PTHR10625 1 16 1.6E-97 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS19060 afcc8756e3b17fd50319e67bf28a283b 370 PANTHER PTHR10625:SF104 32 364 1.6E-97 T 13-09-2016 THL1_RS19060 afcc8756e3b17fd50319e67bf28a283b 370 PANTHER PTHR10625:SF104 1 16 1.6E-97 T 13-09-2016 THL1_RS25280 007c3a05e8c53319d719520900060919 308 SUPERFAMILY SSF54862 21 266 3.77E-72 T 13-09-2016 THL1_RS25280 007c3a05e8c53319d719520900060919 308 Gene3D G3DSA:1.20.5.480 243 284 1.3E-20 T 13-09-2016 THL1_RS25280 007c3a05e8c53319d719520900060919 308 Pfam PF13247 4Fe-4S dicluster domain 88 184 1.2E-24 T 13-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THL1_RS25280 007c3a05e8c53319d719520900060919 308 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 5 284 1.6E-145 T 13-09-2016 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 THL1_RS25280 007c3a05e8c53319d719520900060919 308 Pfam PF12800 4Fe-4S binding domain 33 45 0.073 T 13-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THL1_RS25280 007c3a05e8c53319d719520900060919 308 PANTHER PTHR11938:SF84 1 201 2.5E-109 T 13-09-2016 THL1_RS25280 007c3a05e8c53319d719520900060919 308 Gene3D G3DSA:3.30.70.20 169 223 2.5E-35 T 13-09-2016 THL1_RS25280 007c3a05e8c53319d719520900060919 308 Gene3D G3DSA:3.30.70.20 25 99 2.5E-35 T 13-09-2016 THL1_RS25280 007c3a05e8c53319d719520900060919 308 Gene3D G3DSA:3.30.70.20 100 132 1.3E-11 T 13-09-2016 THL1_RS25280 007c3a05e8c53319d719520900060919 308 PIRSF PIRSF036298 1 303 8.9E-158 T 13-09-2016 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 THL1_RS25280 007c3a05e8c53319d719520900060919 308 Pfam PF09163 Formate dehydrogenase N, transmembrane 242 284 1.0E-23 T 13-09-2016 IPR015246 Formate dehydrogenase, transmembrane THL1_RS25280 007c3a05e8c53319d719520900060919 308 PANTHER PTHR11938 1 201 2.5E-109 T 13-09-2016 THL1_RS25280 007c3a05e8c53319d719520900060919 308 Gene3D G3DSA:3.30.70.20 133 168 3.1E-15 T 13-09-2016 THL1_RS25280 007c3a05e8c53319d719520900060919 308 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 129 140 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 284 776 4.7E-68 T 13-09-2016 IPR001757 P-type ATPase GO:0016021 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 Gene3D G3DSA:3.40.1110.10 524 599 4.6E-4 T 13-09-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 SUPERFAMILY SSF81665 278 309 1.96E-8 T 13-09-2016 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 SUPERFAMILY SSF81665 411 501 1.96E-8 T 13-09-2016 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 PANTHER PTHR24093 87 798 1.1E-177 T 13-09-2016 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 Gene3D G3DSA:3.40.50.1000 481 523 5.6E-49 T 13-09-2016 IPR023214 HAD-like domain THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 Gene3D G3DSA:3.40.50.1000 614 762 5.6E-49 T 13-09-2016 IPR023214 HAD-like domain THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 Gene3D G3DSA:2.70.150.10 275 410 4.8E-23 T 13-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 SUPERFAMILY SSF56784 558 794 1.41E-49 T 13-09-2016 IPR023214 HAD-like domain THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 SUPERFAMILY SSF56784 506 526 1.41E-49 T 13-09-2016 IPR023214 HAD-like domain THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 248 796 4.2E-152 T 13-09-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 Pfam PF00702 haloacid dehalogenase-like hydrolase 504 708 3.9E-32 T 13-09-2016 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 SUPERFAMILY SSF55008 88 164 4.58E-17 T 13-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 Pfam PF00122 E1-E2 ATPase 281 499 3.2E-55 T 13-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 510 516 - T 13-09-2016 IPR018303 P-type ATPase, phosphorylation site THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 PANTHER PTHR24093:SF50 87 798 1.1E-177 T 13-09-2016 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 Pfam PF00403 Heavy-metal-associated domain 98 156 7.1E-12 T 13-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 Gene3D G3DSA:3.30.70.100 94 175 6.9E-16 T 13-09-2016 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 Pfam PF12156 Putative metal-binding domain of cation transport ATPase 6 89 8.1E-28 T 13-09-2016 IPR021993 Putative metal-binding domain of cation transport ATPase THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 231 796 1.8E-136 T 13-09-2016 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 508 522 3.9E-21 T 13-09-2016 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 360 374 3.9E-21 T 13-09-2016 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 717 729 3.9E-21 T 13-09-2016 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 694 713 3.9E-21 T 13-09-2016 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 641 651 3.9E-21 T 13-09-2016 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 SUPERFAMILY SSF81653 317 409 4.97E-23 T 13-09-2016 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 PRINTS PR00941 Cadmium-transporting ATPase signature 376 392 2.2E-6 T 13-09-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 PRINTS PR00941 Cadmium-transporting ATPase signature 97 106 2.2E-6 T 13-09-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 PRINTS PR00941 Cadmium-transporting ATPase signature 108 129 2.2E-6 T 13-09-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 PRINTS PR00941 Cadmium-transporting ATPase signature 395 409 2.2E-6 T 13-09-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 THL1_RS18860 c330dd096159613838b9f066f2a1ceba 799 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 276 797 1.7E-111 T 13-09-2016 THL1_RS14725 d49cbc2c3dbbf69fbb0ffc527255fcb3 408 SUPERFAMILY SSF55031 209 325 8.37E-27 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS14725 d49cbc2c3dbbf69fbb0ffc527255fcb3 408 Gene3D G3DSA:3.40.630.10 347 405 5.6E-113 T 13-09-2016 THL1_RS14725 d49cbc2c3dbbf69fbb0ffc527255fcb3 408 Gene3D G3DSA:3.40.630.10 2 221 5.6E-113 T 13-09-2016 THL1_RS14725 d49cbc2c3dbbf69fbb0ffc527255fcb3 408 Pfam PF01546 Peptidase family M20/M25/M40 78 401 1.2E-35 T 13-09-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 THL1_RS14725 d49cbc2c3dbbf69fbb0ffc527255fcb3 408 SUPERFAMILY SSF53187 2 219 2.65E-92 T 13-09-2016 THL1_RS14725 d49cbc2c3dbbf69fbb0ffc527255fcb3 408 SUPERFAMILY SSF53187 332 404 2.65E-92 T 13-09-2016 THL1_RS14725 d49cbc2c3dbbf69fbb0ffc527255fcb3 408 Gene3D G3DSA:3.30.70.360 222 325 6.7E-35 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS14725 d49cbc2c3dbbf69fbb0ffc527255fcb3 408 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 7 402 2.2E-126 T 13-09-2016 IPR010158 Amidase, hydantoinase/carbamoylase GO:0008152|GO:0016813 THL1_RS14725 d49cbc2c3dbbf69fbb0ffc527255fcb3 408 PIRSF PIRSF001235 1 408 2.6E-137 T 13-09-2016 IPR010158 Amidase, hydantoinase/carbamoylase GO:0008152|GO:0016813 THL1_RS14725 d49cbc2c3dbbf69fbb0ffc527255fcb3 408 PANTHER PTHR32494 5 406 1.2E-156 T 13-09-2016 THL1_RS14725 d49cbc2c3dbbf69fbb0ffc527255fcb3 408 PANTHER PTHR32494:SF6 5 406 1.2E-156 T 13-09-2016 THL1_RS26235 b137ecc4c91ddfb19f682747a97f0306 486 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 6 455 2.9E-153 T 13-09-2016 IPR003846 Uncharacterised protein family UPF0061 THL1_RS26235 b137ecc4c91ddfb19f682747a97f0306 486 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 5 472 46.608 T 13-09-2016 IPR003846 Uncharacterised protein family UPF0061 THL1_RS26235 b137ecc4c91ddfb19f682747a97f0306 486 PANTHER PTHR32057 4 486 1.2E-201 T 13-09-2016 THL1_RS13230 6c134e30aced2ac9236d2aa0c21f440c 283 Gene3D G3DSA:3.30.70.20 73 123 3.7E-12 T 13-09-2016 THL1_RS13230 6c134e30aced2ac9236d2aa0c21f440c 283 Gene3D G3DSA:2.60.40.10 192 276 2.2E-8 T 13-09-2016 IPR013783 Immunoglobulin-like fold THL1_RS13230 6c134e30aced2ac9236d2aa0c21f440c 283 Pfam PF13247 4Fe-4S dicluster domain 61 152 3.6E-18 T 13-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THL1_RS13230 6c134e30aced2ac9236d2aa0c21f440c 283 PANTHER PTHR11938:SF86 1 28 3.0E-14 T 13-09-2016 THL1_RS13230 6c134e30aced2ac9236d2aa0c21f440c 283 Gene3D G3DSA:3.30.70.20 126 188 1.6E-15 T 13-09-2016 THL1_RS13230 6c134e30aced2ac9236d2aa0c21f440c 283 Gene3D G3DSA:3.30.70.20 1 72 1.6E-15 T 13-09-2016 THL1_RS13230 6c134e30aced2ac9236d2aa0c21f440c 283 PANTHER PTHR11938 1 28 3.0E-14 T 13-09-2016 THL1_RS13230 6c134e30aced2ac9236d2aa0c21f440c 283 PANTHER PTHR11938 45 160 3.0E-14 T 13-09-2016 THL1_RS13230 6c134e30aced2ac9236d2aa0c21f440c 283 SUPERFAMILY SSF54862 1 187 3.66E-24 T 13-09-2016 THL1_RS13230 6c134e30aced2ac9236d2aa0c21f440c 283 PANTHER PTHR11938:SF86 45 160 3.0E-14 T 13-09-2016 THL1_RS04030 f62c3c38add7e9508ba08d8edd661611 463 PANTHER PTHR30576 18 458 4.3E-134 T 13-09-2016 THL1_RS04030 f62c3c38add7e9508ba08d8edd661611 463 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 28 460 6.5E-135 T 13-09-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase THL1_RS04030 f62c3c38add7e9508ba08d8edd661611 463 PANTHER PTHR30576:SF0 18 458 4.3E-134 T 13-09-2016 THL1_RS04030 f62c3c38add7e9508ba08d8edd661611 463 Pfam PF13727 CoA-binding domain 77 237 1.0E-21 T 13-09-2016 THL1_RS04030 f62c3c38add7e9508ba08d8edd661611 463 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 29 459 6.0E-136 T 13-09-2016 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 THL1_RS04030 f62c3c38add7e9508ba08d8edd661611 463 Pfam PF02397 Bacterial sugar transferase 275 458 1.9E-55 T 13-09-2016 IPR003362 Bacterial sugar transferase THL1_RS24640 99168caec91aae5050493ff0ddde882b 227 SMART SM00100 5 123 0.0058 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS24640 99168caec91aae5050493ff0ddde882b 227 SUPERFAMILY SSF51206 4 132 1.37E-11 T 13-09-2016 IPR018490 Cyclic nucleotide-binding-like THL1_RS24640 99168caec91aae5050493ff0ddde882b 227 PANTHER PTHR24567 1 227 1.5E-65 T 13-09-2016 THL1_RS24640 99168caec91aae5050493ff0ddde882b 227 Pfam PF13545 Crp-like helix-turn-helix domain 144 209 3.3E-15 T 13-09-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THL1_RS24640 99168caec91aae5050493ff0ddde882b 227 PANTHER PTHR24567:SF22 1 227 1.5E-65 T 13-09-2016 THL1_RS24640 99168caec91aae5050493ff0ddde882b 227 Gene3D G3DSA:1.10.10.10 141 211 8.0E-11 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS24640 99168caec91aae5050493ff0ddde882b 227 Gene3D G3DSA:2.60.120.10 4 131 2.4E-12 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS24640 99168caec91aae5050493ff0ddde882b 227 SUPERFAMILY SSF46785 141 215 4.04E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS01920 ad55b72bcbd7a3b5f779a374f31e079a 458 SUPERFAMILY SSF143548 17 155 1.46E-45 T 13-09-2016 IPR029009 Allosteric substrate binding domain THL1_RS01920 ad55b72bcbd7a3b5f779a374f31e079a 458 PANTHER PTHR30182 1 456 4.9E-242 T 13-09-2016 THL1_RS01920 ad55b72bcbd7a3b5f779a374f31e079a 458 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 454 4.7E-212 T 13-09-2016 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 THL1_RS01920 ad55b72bcbd7a3b5f779a374f31e079a 458 Pfam PF03313 Serine dehydratase alpha chain 186 452 1.1E-103 T 13-09-2016 IPR005130 Serine dehydratase-like, alpha subunit THL1_RS01920 ad55b72bcbd7a3b5f779a374f31e079a 458 PANTHER PTHR30182:SF1 1 456 4.9E-242 T 13-09-2016 THL1_RS01920 ad55b72bcbd7a3b5f779a374f31e079a 458 Gene3D G3DSA:3.30.1330.90 11 156 1.7E-53 T 13-09-2016 IPR029009 Allosteric substrate binding domain THL1_RS01920 ad55b72bcbd7a3b5f779a374f31e079a 458 Pfam PF03315 Serine dehydratase beta chain 4 155 1.1E-56 T 13-09-2016 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 THL1_RS02315 77492b02fa171b36eb51a00f10d4fee0 294 Gene3D G3DSA:3.40.190.10 99 175 5.4E-16 T 13-09-2016 THL1_RS02315 77492b02fa171b36eb51a00f10d4fee0 294 PANTHER PTHR30126 1 288 4.9E-113 T 13-09-2016 THL1_RS02315 77492b02fa171b36eb51a00f10d4fee0 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.3E-22 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS02315 77492b02fa171b36eb51a00f10d4fee0 294 PANTHER PTHR30126:SF17 1 288 4.9E-113 T 13-09-2016 THL1_RS02315 77492b02fa171b36eb51a00f10d4fee0 294 SUPERFAMILY SSF53850 90 291 9.19E-37 T 13-09-2016 THL1_RS02315 77492b02fa171b36eb51a00f10d4fee0 294 Gene3D G3DSA:3.40.190.10 176 256 5.1E-22 T 13-09-2016 THL1_RS02315 77492b02fa171b36eb51a00f10d4fee0 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.9E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS02315 77492b02fa171b36eb51a00f10d4fee0 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.9E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS02315 77492b02fa171b36eb51a00f10d4fee0 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.9E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS02315 77492b02fa171b36eb51a00f10d4fee0 294 SUPERFAMILY SSF46785 1 82 1.54E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02315 77492b02fa171b36eb51a00f10d4fee0 294 Pfam PF03466 LysR substrate binding domain 89 288 1.9E-40 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS02315 77492b02fa171b36eb51a00f10d4fee0 294 Gene3D G3DSA:1.10.10.10 1 80 2.4E-26 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS28025 80701459fcfeeac344055d9900eba2e4 277 SUPERFAMILY SSF52540 27 264 1.33E-60 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28025 80701459fcfeeac344055d9900eba2e4 277 SMART SM00382 55 257 2.1E-9 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS28025 80701459fcfeeac344055d9900eba2e4 277 Pfam PF00005 ABC transporter 46 201 6.0E-32 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS28025 80701459fcfeeac344055d9900eba2e4 277 ProSitePatterns PS00211 ABC transporters family signature. 174 188 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS28025 80701459fcfeeac344055d9900eba2e4 277 Gene3D G3DSA:3.40.50.300 30 271 4.0E-70 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28025 80701459fcfeeac344055d9900eba2e4 277 PANTHER PTHR24220:SF585 32 276 3.6E-141 T 13-09-2016 THL1_RS28025 80701459fcfeeac344055d9900eba2e4 277 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 31 277 3.3E-126 T 13-09-2016 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 THL1_RS28025 80701459fcfeeac344055d9900eba2e4 277 PANTHER PTHR24220 32 276 3.6E-141 T 13-09-2016 THL1_RS20095 96d287de2194b62a0f346904cef577da 434 SUPERFAMILY SSF47384 162 197 3.14E-7 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS20095 96d287de2194b62a0f346904cef577da 434 SUPERFAMILY SSF55874 269 424 1.14E-45 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS20095 96d287de2194b62a0f346904cef577da 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 423 1.0E-24 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS20095 96d287de2194b62a0f346904cef577da 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 369 2.1E-21 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS20095 96d287de2194b62a0f346904cef577da 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 383 2.1E-21 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS20095 96d287de2194b62a0f346904cef577da 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 423 2.1E-21 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS20095 96d287de2194b62a0f346904cef577da 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 404 2.1E-21 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS20095 96d287de2194b62a0f346904cef577da 434 PANTHER PTHR24423:SF360 242 433 3.1E-86 T 13-09-2016 THL1_RS20095 96d287de2194b62a0f346904cef577da 434 PANTHER PTHR24423:SF360 152 196 3.1E-86 T 13-09-2016 THL1_RS20095 96d287de2194b62a0f346904cef577da 434 PANTHER PTHR24423:SF360 21 27 3.1E-86 T 13-09-2016 THL1_RS20095 96d287de2194b62a0f346904cef577da 434 Gene3D G3DSA:3.10.580.10 14 142 1.5E-14 T 13-09-2016 THL1_RS20095 96d287de2194b62a0f346904cef577da 434 PANTHER PTHR24423 152 196 3.1E-86 T 13-09-2016 THL1_RS20095 96d287de2194b62a0f346904cef577da 434 Pfam PF00512 His Kinase A (phospho-acceptor) domain 168 276 4.0E-9 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS20095 96d287de2194b62a0f346904cef577da 434 Pfam PF00571 CBS domain 16 58 1.8E-4 T 13-09-2016 IPR000644 CBS domain THL1_RS20095 96d287de2194b62a0f346904cef577da 434 Pfam PF00571 CBS domain 77 135 0.0044 T 13-09-2016 IPR000644 CBS domain THL1_RS20095 96d287de2194b62a0f346904cef577da 434 Gene3D G3DSA:1.10.287.130 245 273 4.7E-6 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS20095 96d287de2194b62a0f346904cef577da 434 Gene3D G3DSA:1.10.287.130 163 194 4.7E-6 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS20095 96d287de2194b62a0f346904cef577da 434 PANTHER PTHR24423 242 433 3.1E-86 T 13-09-2016 THL1_RS20095 96d287de2194b62a0f346904cef577da 434 PANTHER PTHR24423 21 27 3.1E-86 T 13-09-2016 THL1_RS20095 96d287de2194b62a0f346904cef577da 434 SMART SM00387 318 426 6.8E-35 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS20095 96d287de2194b62a0f346904cef577da 434 Gene3D G3DSA:3.30.565.10 281 424 1.8E-45 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS20095 96d287de2194b62a0f346904cef577da 434 SMART SM00388 168 278 7.5E-4 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS20095 96d287de2194b62a0f346904cef577da 434 SUPERFAMILY SSF54631 13 135 4.89E-12 T 13-09-2016 THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 PANTHER PTHR11063:SF6 9 372 1.0E-117 T 13-09-2016 THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 TIGRFAM TIGR01027 proB: glutamate 5-kinase 10 370 7.2E-130 T 13-09-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 Hamap MF_00456 Glutamate 5-kinase [proB]. 9 262 37.033 T 13-09-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 SUPERFAMILY SSF88697 280 371 2.82E-23 T 13-09-2016 IPR015947 PUA-like domain THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 Pfam PF01472 PUA domain 281 354 3.0E-22 T 13-09-2016 IPR002478 PUA domain GO:0003723 THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 Gene3D G3DSA:3.40.1160.10 4 264 9.3E-58 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 PRINTS PR00474 Glutamate 5-kinase family signature 120 141 3.2E-52 T 13-09-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 PRINTS PR00474 Glutamate 5-kinase family signature 213 233 3.2E-52 T 13-09-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 PRINTS PR00474 Glutamate 5-kinase family signature 80 108 3.2E-52 T 13-09-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 PRINTS PR00474 Glutamate 5-kinase family signature 46 60 3.2E-52 T 13-09-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 PRINTS PR00474 Glutamate 5-kinase family signature 152 179 3.2E-52 T 13-09-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 PIRSF PIRSF000729 4 372 7.0E-130 T 13-09-2016 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 Pfam PF00696 Amino acid kinase family 10 238 2.9E-44 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 PANTHER PTHR11063 9 372 1.0E-117 T 13-09-2016 THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 SUPERFAMILY SSF53633 9 261 1.19E-68 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 Gene3D G3DSA:2.30.130.10 278 370 3.2E-26 T 13-09-2016 IPR015947 PUA-like domain THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 SMART SM00359 281 364 3.6E-16 T 13-09-2016 IPR002478 PUA domain GO:0003723 THL1_RS04835 6c7a06944700b899b481e48c891dfb33 372 ProSitePatterns PS00902 Glutamate 5-kinase signature. 211 228 - T 13-09-2016 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 THL1_RS04915 a34f8ec0c951a8e60e229897bc8898a8 363 Pfam PF01266 FAD dependent oxidoreductase 3 343 5.5E-65 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS04915 a34f8ec0c951a8e60e229897bc8898a8 363 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.0E-5 T 13-09-2016 THL1_RS04915 a34f8ec0c951a8e60e229897bc8898a8 363 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 358 363 2.0E-5 T 13-09-2016 THL1_RS04915 a34f8ec0c951a8e60e229897bc8898a8 363 PANTHER PTHR13847:SF180 1 359 1.9E-97 T 13-09-2016 THL1_RS04915 a34f8ec0c951a8e60e229897bc8898a8 363 Gene3D G3DSA:3.30.9.10 217 301 1.9E-4 T 13-09-2016 THL1_RS04915 a34f8ec0c951a8e60e229897bc8898a8 363 Gene3D G3DSA:3.30.9.10 104 136 1.9E-4 T 13-09-2016 THL1_RS04915 a34f8ec0c951a8e60e229897bc8898a8 363 SUPERFAMILY SSF51905 1 217 4.27E-53 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS04915 a34f8ec0c951a8e60e229897bc8898a8 363 SUPERFAMILY SSF51905 304 359 4.27E-53 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS04915 a34f8ec0c951a8e60e229897bc8898a8 363 PANTHER PTHR13847 1 359 1.9E-97 T 13-09-2016 THL1_RS04915 a34f8ec0c951a8e60e229897bc8898a8 363 Gene3D G3DSA:3.50.50.60 137 216 7.7E-57 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS04915 a34f8ec0c951a8e60e229897bc8898a8 363 Gene3D G3DSA:3.50.50.60 2 84 7.7E-57 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS04915 a34f8ec0c951a8e60e229897bc8898a8 363 Gene3D G3DSA:3.50.50.60 304 359 7.7E-57 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS04915 a34f8ec0c951a8e60e229897bc8898a8 363 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 3 347 7.8E-78 T 13-09-2016 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 UniPathway: UPA00060 THL1_RS04915 a34f8ec0c951a8e60e229897bc8898a8 363 SUPERFAMILY SSF54373 217 304 9.16E-21 T 13-09-2016 THL1_RS18480 0931ba79a70298059d610cf0c648ef56 189 Gene3D G3DSA:2.20.70.10 172 186 1.7E-5 T 13-09-2016 THL1_RS18480 0931ba79a70298059d610cf0c648ef56 189 Pfam PF06938 Protein of unknown function (DUF1285) 38 182 2.7E-60 T 13-09-2016 IPR010707 Protein of unknown function DUF1285 THL1_RS18480 0931ba79a70298059d610cf0c648ef56 189 Gene3D G3DSA:2.30.270.10 89 158 7.2E-32 T 13-09-2016 IPR023361 Protein of unknown function DUF1285, beta-roll domain THL1_RS18480 0931ba79a70298059d610cf0c648ef56 189 Gene3D G3DSA:3.10.540.10 13 88 4.4E-35 T 13-09-2016 THL1_RS18480 0931ba79a70298059d610cf0c648ef56 189 PIRSF PIRSF029557 2 189 9.2E-83 T 13-09-2016 IPR010707 Protein of unknown function DUF1285 THL1_RS04005 c759b42a92a916d173e9462a25f0f6f8 372 SUPERFAMILY SSF56176 6 188 6.54E-37 T 13-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THL1_RS04005 c759b42a92a916d173e9462a25f0f6f8 372 PANTHER PTHR21071:SF6 7 182 3.1E-82 T 13-09-2016 THL1_RS04005 c759b42a92a916d173e9462a25f0f6f8 372 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 372 51.521 T 13-09-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS04005 c759b42a92a916d173e9462a25f0f6f8 372 Gene3D G3DSA:3.90.78.10 274 371 4.1E-26 T 13-09-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS04005 c759b42a92a916d173e9462a25f0f6f8 372 SUPERFAMILY SSF56194 250 371 2.62E-27 T 13-09-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS04005 c759b42a92a916d173e9462a25f0f6f8 372 PANTHER PTHR21071 7 182 3.1E-82 T 13-09-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS04005 c759b42a92a916d173e9462a25f0f6f8 372 PANTHER PTHR21071 223 371 3.1E-82 T 13-09-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS04005 c759b42a92a916d173e9462a25f0f6f8 372 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 263 370 1.6E-21 T 13-09-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS04005 c759b42a92a916d173e9462a25f0f6f8 372 PANTHER PTHR21071:SF6 223 371 3.1E-82 T 13-09-2016 THL1_RS04005 c759b42a92a916d173e9462a25f0f6f8 372 Pfam PF01565 FAD binding domain 27 144 1.1E-15 T 13-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THL1_RS04005 c759b42a92a916d173e9462a25f0f6f8 372 Gene3D G3DSA:3.30.43.10 7 68 3.9E-16 T 13-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 THL1_RS04005 c759b42a92a916d173e9462a25f0f6f8 372 Gene3D G3DSA:3.30.465.10 256 273 1.2E-44 T 13-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THL1_RS04005 c759b42a92a916d173e9462a25f0f6f8 372 Gene3D G3DSA:3.30.465.10 77 190 1.2E-44 T 13-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THL1_RS06660 402842c9c7228f03fe25c80b1d18ad84 236 SUPERFAMILY SSF54534 30 228 3.73E-56 T 13-09-2016 THL1_RS06660 402842c9c7228f03fe25c80b1d18ad84 236 PANTHER PTHR10516 108 230 7.5E-57 T 13-09-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type THL1_RS06660 402842c9c7228f03fe25c80b1d18ad84 236 PANTHER PTHR10516 41 66 7.5E-57 T 13-09-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type THL1_RS06660 402842c9c7228f03fe25c80b1d18ad84 236 Gene3D G3DSA:1.10.287.460 24 112 1.3E-27 T 13-09-2016 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 THL1_RS06660 402842c9c7228f03fe25c80b1d18ad84 236 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 21 130 4.0E-31 T 13-09-2016 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 THL1_RS06660 402842c9c7228f03fe25c80b1d18ad84 236 Gene3D G3DSA:3.10.50.40 113 228 3.7E-44 T 13-09-2016 THL1_RS06660 402842c9c7228f03fe25c80b1d18ad84 236 PANTHER PTHR10516:SF320 108 230 7.5E-57 T 13-09-2016 THL1_RS06660 402842c9c7228f03fe25c80b1d18ad84 236 PANTHER PTHR10516:SF320 41 66 7.5E-57 T 13-09-2016 THL1_RS06660 402842c9c7228f03fe25c80b1d18ad84 236 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 138 225 1.0E-26 T 13-09-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 THL1_RS19090 d7cdec5928744483afe8ebdff2a811f0 306 SUPERFAMILY SSF46785 4 115 1.09E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19090 d7cdec5928744483afe8ebdff2a811f0 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 6.0E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19090 d7cdec5928744483afe8ebdff2a811f0 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 6.0E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19090 d7cdec5928744483afe8ebdff2a811f0 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 6.0E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19090 d7cdec5928744483afe8ebdff2a811f0 306 SUPERFAMILY SSF53850 94 302 1.63E-38 T 13-09-2016 THL1_RS19090 d7cdec5928744483afe8ebdff2a811f0 306 Gene3D G3DSA:3.40.190.10 180 269 1.0E-37 T 13-09-2016 THL1_RS19090 d7cdec5928744483afe8ebdff2a811f0 306 Gene3D G3DSA:1.10.10.10 4 84 9.4E-27 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19090 d7cdec5928744483afe8ebdff2a811f0 306 PANTHER PTHR30346:SF13 4 300 2.5E-174 T 13-09-2016 THL1_RS19090 d7cdec5928744483afe8ebdff2a811f0 306 Pfam PF03466 LysR substrate binding domain 94 299 4.7E-41 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS19090 d7cdec5928744483afe8ebdff2a811f0 306 Gene3D G3DSA:3.40.190.10 94 179 3.8E-24 T 13-09-2016 THL1_RS19090 d7cdec5928744483afe8ebdff2a811f0 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 3.2E-19 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19090 d7cdec5928744483afe8ebdff2a811f0 306 PANTHER PTHR30346 4 300 2.5E-174 T 13-09-2016 THL1_RS07000 4b4fe3afd2ecbd76a1b580a4f97c7c96 221 PANTHER PTHR11260 1 221 4.0E-92 T 13-09-2016 THL1_RS07000 4b4fe3afd2ecbd76a1b580a4f97c7c96 221 Gene3D G3DSA:1.20.1050.10 105 220 3.1E-46 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS07000 4b4fe3afd2ecbd76a1b580a4f97c7c96 221 SUPERFAMILY SSF47616 92 219 2.37E-27 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS07000 4b4fe3afd2ecbd76a1b580a4f97c7c96 221 Gene3D G3DSA:3.40.30.10 3 104 8.5E-26 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS07000 4b4fe3afd2ecbd76a1b580a4f97c7c96 221 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 6 220 2.1E-81 T 13-09-2016 IPR005955 Maleylacetoacetate isomerase GO:0003824|GO:0005737|GO:0009072 THL1_RS07000 4b4fe3afd2ecbd76a1b580a4f97c7c96 221 Pfam PF13417 Glutathione S-transferase, N-terminal domain 7 88 5.6E-13 T 13-09-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THL1_RS07000 4b4fe3afd2ecbd76a1b580a4f97c7c96 221 PANTHER PTHR11260:SF289 1 221 4.0E-92 T 13-09-2016 THL1_RS07000 4b4fe3afd2ecbd76a1b580a4f97c7c96 221 SUPERFAMILY SSF52833 5 115 8.24E-21 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS09785 5afcf4f259963f55f4071d09b041d6b1 390 Pfam PF07687 Peptidase dimerisation domain 173 283 4.5E-23 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS09785 5afcf4f259963f55f4071d09b041d6b1 390 SUPERFAMILY SSF53187 306 383 2.77E-59 T 13-09-2016 THL1_RS09785 5afcf4f259963f55f4071d09b041d6b1 390 SUPERFAMILY SSF53187 8 175 2.77E-59 T 13-09-2016 THL1_RS09785 5afcf4f259963f55f4071d09b041d6b1 390 PANTHER PTHR11014 1 388 8.9E-105 T 13-09-2016 THL1_RS09785 5afcf4f259963f55f4071d09b041d6b1 390 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 102 139 - T 13-09-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 THL1_RS09785 5afcf4f259963f55f4071d09b041d6b1 390 SUPERFAMILY SSF55031 176 279 4.19E-20 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS09785 5afcf4f259963f55f4071d09b041d6b1 390 PANTHER PTHR11014:SF80 1 388 8.9E-105 T 13-09-2016 THL1_RS09785 5afcf4f259963f55f4071d09b041d6b1 390 Gene3D G3DSA:3.40.630.10 325 381 6.7E-63 T 13-09-2016 THL1_RS09785 5afcf4f259963f55f4071d09b041d6b1 390 Gene3D G3DSA:3.40.630.10 8 184 6.7E-63 T 13-09-2016 THL1_RS09785 5afcf4f259963f55f4071d09b041d6b1 390 Gene3D G3DSA:3.30.70.360 185 279 5.2E-23 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS09785 5afcf4f259963f55f4071d09b041d6b1 390 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 8 379 5.1E-122 T 13-09-2016 IPR010169 Acetylornithine deacetylase (ArgE) GO:0005737|GO:0006526|GO:0008270|GO:0008777|GO:0050897 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154|UniPathway: UPA00068 THL1_RS09785 5afcf4f259963f55f4071d09b041d6b1 390 Pfam PF01546 Peptidase family M20/M25/M40 69 380 7.0E-35 T 13-09-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 THL1_RS10700 3a1e9a925b9bbe58f80ff1c4dd8b9ff5 262 Pfam PF04205 FMN-binding domain 147 245 1.1E-13 T 13-09-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 THL1_RS10700 3a1e9a925b9bbe58f80ff1c4dd8b9ff5 262 PIRSF PIRSF009437 1 262 1.2E-105 T 13-09-2016 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 THL1_RS10700 3a1e9a925b9bbe58f80ff1c4dd8b9ff5 262 PANTHER PTHR37838 1 261 6.1E-100 T 13-09-2016 THL1_RS10700 3a1e9a925b9bbe58f80ff1c4dd8b9ff5 262 Hamap MF_00427 Na(+)-translocating NADH-quinone reductase subunit C [nqrC]. 6 260 36.336 T 13-09-2016 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 THL1_RS10700 3a1e9a925b9bbe58f80ff1c4dd8b9ff5 262 TIGRFAM TIGR01938 nqrC: NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit 6 256 4.8E-91 T 13-09-2016 IPR010204 Na(+)-translocating NADH-quinone reductase subunit C GO:0006814|GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0055114 THL1_RS10700 3a1e9a925b9bbe58f80ff1c4dd8b9ff5 262 PANTHER PTHR37838:SF1 1 261 6.1E-100 T 13-09-2016 THL1_RS10700 3a1e9a925b9bbe58f80ff1c4dd8b9ff5 262 SMART SM00900 147 248 8.8E-34 T 13-09-2016 IPR007329 FMN-binding GO:0010181|GO:0016020 THL1_RS06025 3dc5ed2ab3c17bda4bdd8839ead7e78a 556 Pfam PF00682 HMGL-like 33 313 2.3E-77 T 13-09-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 THL1_RS06025 3dc5ed2ab3c17bda4bdd8839ead7e78a 556 SUPERFAMILY SSF89000 388 438 1.33E-13 T 13-09-2016 THL1_RS06025 3dc5ed2ab3c17bda4bdd8839ead7e78a 556 Pfam PF08502 LeuA allosteric (dimerisation) domain 422 547 2.2E-28 T 13-09-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 THL1_RS06025 3dc5ed2ab3c17bda4bdd8839ead7e78a 556 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 243 256 - T 13-09-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 THL1_RS06025 3dc5ed2ab3c17bda4bdd8839ead7e78a 556 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 7 548 4.0E-244 T 13-09-2016 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 THL1_RS06025 3dc5ed2ab3c17bda4bdd8839ead7e78a 556 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 40 56 - T 13-09-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 THL1_RS06025 3dc5ed2ab3c17bda4bdd8839ead7e78a 556 SUPERFAMILY SSF110921 448 547 3.27E-32 T 13-09-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 THL1_RS06025 3dc5ed2ab3c17bda4bdd8839ead7e78a 556 PANTHER PTHR10277:SF28 1 556 5.6E-292 T 13-09-2016 THL1_RS06025 3dc5ed2ab3c17bda4bdd8839ead7e78a 556 Gene3D G3DSA:3.20.20.70 11 394 1.9E-148 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS06025 3dc5ed2ab3c17bda4bdd8839ead7e78a 556 SUPERFAMILY SSF51569 22 330 1.04E-98 T 13-09-2016 THL1_RS06025 3dc5ed2ab3c17bda4bdd8839ead7e78a 556 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 8 549 54.617 T 13-09-2016 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 THL1_RS06025 3dc5ed2ab3c17bda4bdd8839ead7e78a 556 SMART SM00917 422 548 2.5E-28 T 13-09-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 THL1_RS06025 3dc5ed2ab3c17bda4bdd8839ead7e78a 556 PANTHER PTHR10277 1 556 5.6E-292 T 13-09-2016 THL1_RS11055 39d426ff1fced66437eaca3d227326d8 825 PANTHER PTHR30489 1 188 5.9E-201 T 13-09-2016 THL1_RS11055 39d426ff1fced66437eaca3d227326d8 825 PANTHER PTHR30489:SF6 216 824 5.9E-201 T 13-09-2016 THL1_RS11055 39d426ff1fced66437eaca3d227326d8 825 PANTHER PTHR30489:SF6 1 188 5.9E-201 T 13-09-2016 THL1_RS11055 39d426ff1fced66437eaca3d227326d8 825 PANTHER PTHR30489 216 824 5.9E-201 T 13-09-2016 THL1_RS11055 39d426ff1fced66437eaca3d227326d8 825 Pfam PF12704 MacB-like periplasmic core domain 466 628 1.0E-8 T 13-09-2016 IPR025857 MacB-like periplasmic core domain THL1_RS11055 39d426ff1fced66437eaca3d227326d8 825 Pfam PF02687 FtsX-like permease family 248 370 9.0E-8 T 13-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 THL1_RS11055 39d426ff1fced66437eaca3d227326d8 825 Pfam PF02687 FtsX-like permease family 698 814 1.3E-11 T 13-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 THL1_RS00625 a63ae04ab369e317b0d49bfde5ef4e81 403 SUPERFAMILY SSF109604 149 400 1.65E-38 T 13-09-2016 THL1_RS00625 a63ae04ab369e317b0d49bfde5ef4e81 403 Gene3D G3DSA:1.10.3150.10 149 397 9.1E-36 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS00625 a63ae04ab369e317b0d49bfde5ef4e81 403 SUPERFAMILY SSF52172 9 130 1.04E-22 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS00625 a63ae04ab369e317b0d49bfde5ef4e81 403 Pfam PF00072 Response regulator receiver domain 10 123 8.1E-15 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS00625 a63ae04ab369e317b0d49bfde5ef4e81 403 Gene3D G3DSA:3.40.50.2300 8 130 9.4E-23 T 13-09-2016 THL1_RS00625 a63ae04ab369e317b0d49bfde5ef4e81 403 SMART SM00448 8 123 8.3E-17 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS00625 a63ae04ab369e317b0d49bfde5ef4e81 403 PANTHER PTHR33525 140 346 2.8E-17 T 13-09-2016 THL1_RS00625 a63ae04ab369e317b0d49bfde5ef4e81 403 Pfam PF08668 HDOD domain 161 346 4.0E-36 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS01865 7a703547a17e59065b6ff5cde1673d10 398 Pfam PF00563 EAL domain 146 379 9.7E-64 T 13-09-2016 IPR001633 EAL domain THL1_RS01865 7a703547a17e59065b6ff5cde1673d10 398 PANTHER PTHR33121:SF13 153 395 9.4E-55 T 13-09-2016 THL1_RS01865 7a703547a17e59065b6ff5cde1673d10 398 PANTHER PTHR33121 153 395 9.4E-55 T 13-09-2016 THL1_RS01865 7a703547a17e59065b6ff5cde1673d10 398 SMART SM00052 137 384 1.3E-67 T 13-09-2016 IPR001633 EAL domain THL1_RS01865 7a703547a17e59065b6ff5cde1673d10 398 SUPERFAMILY SSF141868 145 391 1.7E-71 T 13-09-2016 IPR001633 EAL domain THL1_RS01865 7a703547a17e59065b6ff5cde1673d10 398 SUPERFAMILY SSF52172 1 182 3.98E-23 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS01865 7a703547a17e59065b6ff5cde1673d10 398 Gene3D G3DSA:3.40.50.2300 1 124 1.4E-20 T 13-09-2016 THL1_RS01865 7a703547a17e59065b6ff5cde1673d10 398 Pfam PF00072 Response regulator receiver domain 6 95 1.1E-13 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS01865 7a703547a17e59065b6ff5cde1673d10 398 SMART SM00448 4 122 1.0E-14 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS01865 7a703547a17e59065b6ff5cde1673d10 398 Gene3D G3DSA:3.20.20.450 147 391 1.6E-74 T 13-09-2016 IPR001633 EAL domain THL1_RS10275 7160ffceea9bf7d2ec5265a7606771f1 885 PANTHER PTHR11533:SF152 619 884 0.0 T 13-09-2016 THL1_RS10275 7160ffceea9bf7d2ec5265a7606771f1 885 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 319 331 2.9E-10 T 13-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THL1_RS10275 7160ffceea9bf7d2ec5265a7606771f1 885 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 182 197 2.9E-10 T 13-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THL1_RS10275 7160ffceea9bf7d2ec5265a7606771f1 885 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 132 147 2.9E-10 T 13-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THL1_RS10275 7160ffceea9bf7d2ec5265a7606771f1 885 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 264 274 2.9E-10 T 13-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THL1_RS10275 7160ffceea9bf7d2ec5265a7606771f1 885 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 300 315 2.9E-10 T 13-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THL1_RS10275 7160ffceea9bf7d2ec5265a7606771f1 885 Gene3D G3DSA:1.25.50.10 556 885 3.3E-131 T 13-09-2016 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal THL1_RS10275 7160ffceea9bf7d2ec5265a7606771f1 885 SUPERFAMILY SSF55486 210 457 1.67E-78 T 13-09-2016 THL1_RS10275 7160ffceea9bf7d2ec5265a7606771f1 885 Gene3D G3DSA:1.10.390.10 314 457 2.8E-32 T 13-09-2016 THL1_RS10275 7160ffceea9bf7d2ec5265a7606771f1 885 SUPERFAMILY SSF63737 4 199 1.44E-42 T 13-09-2016 THL1_RS10275 7160ffceea9bf7d2ec5265a7606771f1 885 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 13 884 0.0 T 13-09-2016 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 THL1_RS10275 7160ffceea9bf7d2ec5265a7606771f1 885 PANTHER PTHR11533 2 595 0.0 T 13-09-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 THL1_RS10275 7160ffceea9bf7d2ec5265a7606771f1 885 Pfam PF01433 Peptidase family M1 96 390 1.6E-70 T 13-09-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THL1_RS10275 7160ffceea9bf7d2ec5265a7606771f1 885 PANTHER PTHR11533:SF152 2 595 0.0 T 13-09-2016 THL1_RS10275 7160ffceea9bf7d2ec5265a7606771f1 885 Pfam PF11940 Domain of unknown function (DUF3458) 464 840 1.2E-143 T 13-09-2016 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal THL1_RS10275 7160ffceea9bf7d2ec5265a7606771f1 885 PANTHER PTHR11533 619 884 0.0 T 13-09-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 THL1_RS28445 c0c1252c1bd16449ea330b6679fee266 85 SUPERFAMILY SSF81333 3 78 1.15E-18 T 13-09-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 THL1_RS28445 c0c1252c1bd16449ea330b6679fee266 85 PRINTS PR00124 ATP synthase C subunit signature 11 30 1.5E-6 T 13-09-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 THL1_RS28445 c0c1252c1bd16449ea330b6679fee266 85 PRINTS PR00124 ATP synthase C subunit signature 32 47 1.5E-6 T 13-09-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 THL1_RS28445 c0c1252c1bd16449ea330b6679fee266 85 PRINTS PR00124 ATP synthase C subunit signature 49 74 1.5E-6 T 13-09-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 THL1_RS28445 c0c1252c1bd16449ea330b6679fee266 85 Gene3D G3DSA:1.20.20.10 2 78 1.8E-32 T 13-09-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 THL1_RS28445 c0c1252c1bd16449ea330b6679fee266 85 Hamap MF_01396 ATP synthase subunit c [atpH]. 8 76 14.624 T 13-09-2016 THL1_RS28445 c0c1252c1bd16449ea330b6679fee266 85 ProSitePatterns PS00605 ATP synthase c subunit signature. 39 60 - T 13-09-2016 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site THL1_RS28445 c0c1252c1bd16449ea330b6679fee266 85 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 20 76 1.4E-29 T 13-09-2016 IPR005953 ATPase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 THL1_RS28445 c0c1252c1bd16449ea330b6679fee266 85 Pfam PF00137 ATP synthase subunit C 10 72 3.0E-9 T 13-09-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 THL1_RS22880 1d185ab2918d672894a8b82ea1a1f402 501 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 16 500 2.0E-205 T 13-09-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 THL1_RS22880 1d185ab2918d672894a8b82ea1a1f402 501 SUPERFAMILY SSF55681 158 498 4.24E-124 T 13-09-2016 THL1_RS22880 1d185ab2918d672894a8b82ea1a1f402 501 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 21 500 44.032 T 13-09-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 THL1_RS22880 1d185ab2918d672894a8b82ea1a1f402 501 PANTHER PTHR22594 1 500 6.0E-273 T 13-09-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS22880 1d185ab2918d672894a8b82ea1a1f402 501 Gene3D G3DSA:3.30.930.10 153 496 2.9E-122 T 13-09-2016 THL1_RS22880 1d185ab2918d672894a8b82ea1a1f402 501 Pfam PF00152 tRNA synthetases class II (D, K and N) 159 497 1.1E-83 T 13-09-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS22880 1d185ab2918d672894a8b82ea1a1f402 501 Pfam PF01336 OB-fold nucleic acid binding domain 69 141 8.9E-9 T 13-09-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 THL1_RS22880 1d185ab2918d672894a8b82ea1a1f402 501 Gene3D G3DSA:2.40.50.140 16 150 2.3E-40 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS22880 1d185ab2918d672894a8b82ea1a1f402 501 PANTHER PTHR22594:SF4 1 500 6.0E-273 T 13-09-2016 THL1_RS22880 1d185ab2918d672894a8b82ea1a1f402 501 SUPERFAMILY SSF50249 13 151 1.35E-36 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS22880 1d185ab2918d672894a8b82ea1a1f402 501 PRINTS PR00982 Lysyl-tRNA synthetase signature 258 275 5.4E-38 T 13-09-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 THL1_RS22880 1d185ab2918d672894a8b82ea1a1f402 501 PRINTS PR00982 Lysyl-tRNA synthetase signature 240 253 5.4E-38 T 13-09-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 THL1_RS22880 1d185ab2918d672894a8b82ea1a1f402 501 PRINTS PR00982 Lysyl-tRNA synthetase signature 211 227 5.4E-38 T 13-09-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 THL1_RS22880 1d185ab2918d672894a8b82ea1a1f402 501 PRINTS PR00982 Lysyl-tRNA synthetase signature 195 205 5.4E-38 T 13-09-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 THL1_RS22880 1d185ab2918d672894a8b82ea1a1f402 501 PRINTS PR00982 Lysyl-tRNA synthetase signature 382 398 5.4E-38 T 13-09-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 THL1_RS09725 2b29d0f7eab4fb34ed0af165c5f89310 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 95 109 2.6E-27 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS09725 2b29d0f7eab4fb34ed0af165c5f89310 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 142 151 2.6E-27 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS09725 2b29d0f7eab4fb34ed0af165c5f89310 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 193 201 2.6E-27 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS09725 2b29d0f7eab4fb34ed0af165c5f89310 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 81 95 2.6E-27 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS09725 2b29d0f7eab4fb34ed0af165c5f89310 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 117 136 2.6E-27 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS09725 2b29d0f7eab4fb34ed0af165c5f89310 322 PRINTS PR00409 Phthalate dioxygenase reductase family signature 32 42 2.6E-27 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS09725 2b29d0f7eab4fb34ed0af165c5f89310 322 SUPERFAMILY SSF54292 215 320 2.96E-25 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS09725 2b29d0f7eab4fb34ed0af165c5f89310 322 Gene3D G3DSA:3.40.50.80 107 221 3.4E-19 T 13-09-2016 THL1_RS09725 2b29d0f7eab4fb34ed0af165c5f89310 322 PANTHER PTHR22924:SF20 9 276 1.1E-50 T 13-09-2016 THL1_RS09725 2b29d0f7eab4fb34ed0af165c5f89310 322 SUPERFAMILY SSF52343 107 223 2.88E-21 T 13-09-2016 THL1_RS09725 2b29d0f7eab4fb34ed0af165c5f89310 322 Gene3D G3DSA:2.40.30.10 4 105 3.4E-26 T 13-09-2016 THL1_RS09725 2b29d0f7eab4fb34ed0af165c5f89310 322 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 239 313 4.0E-14 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS09725 2b29d0f7eab4fb34ed0af165c5f89310 322 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 269 277 - T 13-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THL1_RS09725 2b29d0f7eab4fb34ed0af165c5f89310 322 SUPERFAMILY SSF63380 5 105 5.96E-24 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS09725 2b29d0f7eab4fb34ed0af165c5f89310 322 Pfam PF00970 Oxidoreductase FAD-binding domain 10 103 1.3E-4 T 13-09-2016 IPR008333 Oxidoreductase, FAD-binding domain THL1_RS09725 2b29d0f7eab4fb34ed0af165c5f89310 322 PANTHER PTHR22924 9 276 1.1E-50 T 13-09-2016 THL1_RS09725 2b29d0f7eab4fb34ed0af165c5f89310 322 Gene3D G3DSA:3.10.20.30 222 319 1.1E-26 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS09410 30836cff575aa9e6d0f6a2495e5700f8 426 Pfam PF05161 MOFRL family 307 412 1.4E-34 T 13-09-2016 IPR007835 MOFRL domain THL1_RS09410 30836cff575aa9e6d0f6a2495e5700f8 426 Pfam PF13660 Domain of unknown function (DUF4147) 9 229 1.4E-81 T 13-09-2016 IPR025286 MOFRL-associated domain THL1_RS09410 30836cff575aa9e6d0f6a2495e5700f8 426 PANTHER PTHR12227:SF0 6 423 1.6E-142 T 13-09-2016 THL1_RS09410 30836cff575aa9e6d0f6a2495e5700f8 426 Gene3D G3DSA:3.40.1480.10 241 419 6.3E-65 T 13-09-2016 IPR007835 MOFRL domain THL1_RS09410 30836cff575aa9e6d0f6a2495e5700f8 426 PANTHER PTHR12227 6 423 1.6E-142 T 13-09-2016 THL1_RS09410 30836cff575aa9e6d0f6a2495e5700f8 426 Gene3D G3DSA:3.40.50.10180 9 240 9.1E-100 T 13-09-2016 THL1_RS09410 30836cff575aa9e6d0f6a2495e5700f8 426 SUPERFAMILY SSF82544 4 418 3.4E-148 T 13-09-2016 THL1_RS22640 ed3bb452411caadf08cc6eec637640c7 246 Pfam PF00318 Ribosomal protein S2 9 224 6.8E-94 T 13-09-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS22640 ed3bb452411caadf08cc6eec637640c7 246 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 13-09-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 THL1_RS22640 ed3bb452411caadf08cc6eec637640c7 246 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 41.566 T 13-09-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 THL1_RS22640 ed3bb452411caadf08cc6eec637640c7 246 Gene3D G3DSA:1.10.287.610 100 152 1.4E-25 T 13-09-2016 THL1_RS22640 ed3bb452411caadf08cc6eec637640c7 246 Gene3D G3DSA:3.40.50.10490 158 235 1.4E-64 T 13-09-2016 THL1_RS22640 ed3bb452411caadf08cc6eec637640c7 246 Gene3D G3DSA:3.40.50.10490 23 99 1.4E-64 T 13-09-2016 THL1_RS22640 ed3bb452411caadf08cc6eec637640c7 246 PANTHER PTHR12534 1 240 6.8E-118 T 13-09-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 THL1_RS22640 ed3bb452411caadf08cc6eec637640c7 246 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 13-09-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 THL1_RS22640 ed3bb452411caadf08cc6eec637640c7 246 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 226 2.2E-104 T 13-09-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 THL1_RS22640 ed3bb452411caadf08cc6eec637640c7 246 PRINTS PR00395 Ribosomal protein S2 signature 158 175 9.3E-38 T 13-09-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS22640 ed3bb452411caadf08cc6eec637640c7 246 PRINTS PR00395 Ribosomal protein S2 signature 175 186 9.3E-38 T 13-09-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS22640 ed3bb452411caadf08cc6eec637640c7 246 PRINTS PR00395 Ribosomal protein S2 signature 37 46 9.3E-38 T 13-09-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS22640 ed3bb452411caadf08cc6eec637640c7 246 PRINTS PR00395 Ribosomal protein S2 signature 6 24 9.3E-38 T 13-09-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS22640 ed3bb452411caadf08cc6eec637640c7 246 PRINTS PR00395 Ribosomal protein S2 signature 196 210 9.3E-38 T 13-09-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS22640 ed3bb452411caadf08cc6eec637640c7 246 PRINTS PR00395 Ribosomal protein S2 signature 87 104 9.3E-38 T 13-09-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS22640 ed3bb452411caadf08cc6eec637640c7 246 SUPERFAMILY SSF52313 6 229 1.23E-94 T 13-09-2016 IPR023591 Ribosomal protein S2, flavodoxin-like domain THL1_RS07120 003b42c2d464a2d7db252953aeb31bb3 260 SUPERFAMILY SSF51735 14 256 9.39E-66 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07120 003b42c2d464a2d7db252953aeb31bb3 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 6.3E-31 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07120 003b42c2d464a2d7db252953aeb31bb3 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 6.3E-31 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07120 003b42c2d464a2d7db252953aeb31bb3 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 18 35 6.3E-31 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07120 003b42c2d464a2d7db252953aeb31bb3 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 6.3E-31 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07120 003b42c2d464a2d7db252953aeb31bb3 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 6.3E-31 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07120 003b42c2d464a2d7db252953aeb31bb3 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 6.3E-31 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07120 003b42c2d464a2d7db252953aeb31bb3 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 255 1.4E-55 T 13-09-2016 THL1_RS07120 003b42c2d464a2d7db252953aeb31bb3 260 Gene3D G3DSA:3.40.50.720 13 256 6.2E-70 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07120 003b42c2d464a2d7db252953aeb31bb3 260 PANTHER PTHR24322 168 199 5.0E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07120 003b42c2d464a2d7db252953aeb31bb3 260 PANTHER PTHR24322 20 152 5.0E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07120 003b42c2d464a2d7db252953aeb31bb3 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS07120 003b42c2d464a2d7db252953aeb31bb3 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 6.3E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07120 003b42c2d464a2d7db252953aeb31bb3 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 6.3E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07120 003b42c2d464a2d7db252953aeb31bb3 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 106 6.3E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS03600 357a21ad2d6fe8c52a834c53b5cfd894 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 3.3E-34 T 13-09-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS03600 357a21ad2d6fe8c52a834c53b5cfd894 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 3.3E-34 T 13-09-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS03600 357a21ad2d6fe8c52a834c53b5cfd894 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 3.3E-34 T 13-09-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS03600 357a21ad2d6fe8c52a834c53b5cfd894 177 SUPERFAMILY SSF56053 83 177 5.23E-37 T 13-09-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS03600 357a21ad2d6fe8c52a834c53b5cfd894 177 PANTHER PTHR11655:SF14 1 176 2.4E-91 T 13-09-2016 THL1_RS03600 357a21ad2d6fe8c52a834c53b5cfd894 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 13-09-2016 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03600 357a21ad2d6fe8c52a834c53b5cfd894 177 Pfam PF00347 Ribosomal protein L6 90 164 1.2E-19 T 13-09-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS03600 357a21ad2d6fe8c52a834c53b5cfd894 177 Pfam PF00347 Ribosomal protein L6 12 82 1.4E-17 T 13-09-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS03600 357a21ad2d6fe8c52a834c53b5cfd894 177 PANTHER PTHR11655 1 176 2.4E-91 T 13-09-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS03600 357a21ad2d6fe8c52a834c53b5cfd894 177 PIRSF PIRSF002162 1 177 3.2E-47 T 13-09-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS03600 357a21ad2d6fe8c52a834c53b5cfd894 177 SUPERFAMILY SSF56053 1 82 1.44E-23 T 13-09-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS03600 357a21ad2d6fe8c52a834c53b5cfd894 177 Gene3D G3DSA:3.90.930.12 83 177 6.3E-42 T 13-09-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS03600 357a21ad2d6fe8c52a834c53b5cfd894 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 38.37 T 13-09-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS03600 357a21ad2d6fe8c52a834c53b5cfd894 177 Gene3D G3DSA:3.90.930.12 2 82 3.6E-29 T 13-09-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS03600 357a21ad2d6fe8c52a834c53b5cfd894 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 3.0E-77 T 13-09-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS14375 3293fa017473df60141e1288fb37b6b1 280 Pfam PF09339 IclR helix-turn-helix domain 36 87 3.9E-15 T 13-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 THL1_RS14375 3293fa017473df60141e1288fb37b6b1 280 Pfam PF01614 Bacterial transcriptional regulator 151 276 5.8E-36 T 13-09-2016 IPR014757 Transcription regulator IclR, C-terminal THL1_RS14375 3293fa017473df60141e1288fb37b6b1 280 TIGRFAM TIGR02431 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 31 277 7.9E-102 T 13-09-2016 IPR012794 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR GO:0003677|GO:0045893|GO:0046278 THL1_RS14375 3293fa017473df60141e1288fb37b6b1 280 Gene3D G3DSA:3.30.450.40 100 278 1.6E-57 T 13-09-2016 IPR029016 GAF domain-like THL1_RS14375 3293fa017473df60141e1288fb37b6b1 280 SUPERFAMILY SSF55781 99 278 7.06E-49 T 13-09-2016 IPR029016 GAF domain-like THL1_RS14375 3293fa017473df60141e1288fb37b6b1 280 PANTHER PTHR30136 12 278 3.1E-107 T 13-09-2016 THL1_RS14375 3293fa017473df60141e1288fb37b6b1 280 Gene3D G3DSA:1.10.10.10 22 92 8.9E-31 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14375 3293fa017473df60141e1288fb37b6b1 280 PANTHER PTHR30136:SF10 12 278 3.1E-107 T 13-09-2016 THL1_RS14375 3293fa017473df60141e1288fb37b6b1 280 SMART SM00346 34 122 1.1E-34 T 13-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 THL1_RS14375 3293fa017473df60141e1288fb37b6b1 280 SUPERFAMILY SSF46785 35 106 6.47E-12 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS23385 9d1a430f3d97397085da3925c9bbb1fa 384 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 72 269 1.8E-33 T 13-09-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THL1_RS23385 9d1a430f3d97397085da3925c9bbb1fa 384 SUPERFAMILY SSF111369 60 273 2.75E-43 T 13-09-2016 THL1_RS23385 9d1a430f3d97397085da3925c9bbb1fa 384 PANTHER PTHR30469 321 377 2.1E-121 T 13-09-2016 THL1_RS23385 9d1a430f3d97397085da3925c9bbb1fa 384 PANTHER PTHR30469 1 305 2.1E-121 T 13-09-2016 THL1_RS23385 9d1a430f3d97397085da3925c9bbb1fa 384 Gene3D G3DSA:2.40.50.100 163 194 3.3E-14 T 13-09-2016 THL1_RS23385 9d1a430f3d97397085da3925c9bbb1fa 384 Gene3D G3DSA:2.40.50.100 70 102 3.3E-14 T 13-09-2016 THL1_RS23385 9d1a430f3d97397085da3925c9bbb1fa 384 PANTHER PTHR30469:SF11 321 377 2.1E-121 T 13-09-2016 THL1_RS23385 9d1a430f3d97397085da3925c9bbb1fa 384 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 366 1.0E-77 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS23385 9d1a430f3d97397085da3925c9bbb1fa 384 PANTHER PTHR30469:SF11 1 305 2.1E-121 T 13-09-2016 THL1_RS08785 321472677c36131a27e0ce2a26b6e16c 618 PANTHER PTHR24221 37 614 3.1E-300 T 13-09-2016 THL1_RS08785 321472677c36131a27e0ce2a26b6e16c 618 SUPERFAMILY SSF52540 361 605 5.63E-94 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08785 321472677c36131a27e0ce2a26b6e16c 618 Pfam PF00005 ABC transporter 386 535 1.2E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS08785 321472677c36131a27e0ce2a26b6e16c 618 Gene3D G3DSA:3.40.50.300 369 601 1.4E-85 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08785 321472677c36131a27e0ce2a26b6e16c 618 Gene3D G3DSA:1.20.1560.10 40 350 3.2E-69 T 13-09-2016 THL1_RS08785 321472677c36131a27e0ce2a26b6e16c 618 Pfam PF00664 ABC transporter transmembrane region 53 324 1.2E-38 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS08785 321472677c36131a27e0ce2a26b6e16c 618 SMART SM00382 395 581 1.4E-16 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS08785 321472677c36131a27e0ce2a26b6e16c 618 SUPERFAMILY SSF90123 40 350 3.79E-65 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS08785 321472677c36131a27e0ce2a26b6e16c 618 ProSitePatterns PS00211 ABC transporters family signature. 507 521 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS08785 321472677c36131a27e0ce2a26b6e16c 618 PANTHER PTHR24221:SF18 37 614 3.1E-300 T 13-09-2016 THL1_RS27530 2462d04263ca592a783c133cf5589ac5 439 SUPERFAMILY SSF111352 29 418 2.62E-133 T 13-09-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 THL1_RS27530 2462d04263ca592a783c133cf5589ac5 439 Pfam PF00909 Ammonium Transporter Family 35 437 2.2E-124 T 13-09-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 THL1_RS27530 2462d04263ca592a783c133cf5589ac5 439 TIGRFAM TIGR00836 amt: ammonium transporter 33 437 3.1E-147 T 13-09-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 THL1_RS27530 2462d04263ca592a783c133cf5589ac5 439 ProSitePatterns PS01219 Ammonium transporters signature. 195 220 - T 13-09-2016 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 THL1_RS27530 2462d04263ca592a783c133cf5589ac5 439 PANTHER PTHR11730 26 439 1.5E-192 T 13-09-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 THL1_RS27530 2462d04263ca592a783c133cf5589ac5 439 PANTHER PTHR11730:SF17 26 439 1.5E-192 T 13-09-2016 THL1_RS27530 2462d04263ca592a783c133cf5589ac5 439 Gene3D G3DSA:1.10.3430.10 28 418 3.7E-146 T 13-09-2016 IPR029020 Ammonium/urea transporter THL1_RS20465 be4f47b4fae9ff858cee1b2a2fbfd1b0 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 6.2E-13 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20465 be4f47b4fae9ff858cee1b2a2fbfd1b0 208 PANTHER PTHR30055 1 161 1.7E-19 T 13-09-2016 THL1_RS20465 be4f47b4fae9ff858cee1b2a2fbfd1b0 208 SUPERFAMILY SSF46689 8 83 1.3E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS20465 be4f47b4fae9ff858cee1b2a2fbfd1b0 208 Gene3D G3DSA:1.10.357.10 60 165 5.4E-15 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS20465 be4f47b4fae9ff858cee1b2a2fbfd1b0 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 3.8E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20465 be4f47b4fae9ff858cee1b2a2fbfd1b0 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 3.8E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20465 be4f47b4fae9ff858cee1b2a2fbfd1b0 208 PANTHER PTHR30055:SF33 1 161 1.7E-19 T 13-09-2016 THL1_RS20465 be4f47b4fae9ff858cee1b2a2fbfd1b0 208 Gene3D G3DSA:1.10.10.60 13 59 7.7E-18 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS10425 dd080ce006580044bbf68760031f79ea 197 PANTHER PTHR11260:SF285 1 191 1.0E-47 T 13-09-2016 THL1_RS10425 dd080ce006580044bbf68760031f79ea 197 SUPERFAMILY SSF47616 71 193 8.6E-26 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS10425 dd080ce006580044bbf68760031f79ea 197 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 78 1.3E-16 T 13-09-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THL1_RS10425 dd080ce006580044bbf68760031f79ea 197 SUPERFAMILY SSF52833 1 83 1.99E-25 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS10425 dd080ce006580044bbf68760031f79ea 197 Gene3D G3DSA:3.40.30.10 1 84 3.4E-26 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS10425 dd080ce006580044bbf68760031f79ea 197 Pfam PF00043 Glutathione S-transferase, C-terminal domain 123 189 9.4E-12 T 13-09-2016 IPR004046 Glutathione S-transferase, C-terminal THL1_RS10425 dd080ce006580044bbf68760031f79ea 197 PANTHER PTHR11260 1 191 1.0E-47 T 13-09-2016 THL1_RS10425 dd080ce006580044bbf68760031f79ea 197 Gene3D G3DSA:1.20.1050.10 85 191 1.1E-28 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS02590 f94f98c37a5c42b7e65f167968c16cea 109 Gene3D G3DSA:3.40.250.10 2 97 3.8E-28 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS02590 f94f98c37a5c42b7e65f167968c16cea 109 SUPERFAMILY SSF52821 1 102 9.56E-28 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS02590 f94f98c37a5c42b7e65f167968c16cea 109 Pfam PF00581 Rhodanese-like domain 10 96 2.3E-15 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS02590 f94f98c37a5c42b7e65f167968c16cea 109 Hamap MF_01009 Thiosulfate sulfurtransferase GlpE [glpE]. 2 105 30.621 T 13-09-2016 IPR023695 Thiosulfate sulfurtransferase, bacterial GO:0004792|GO:0005737 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 THL1_RS02590 f94f98c37a5c42b7e65f167968c16cea 109 SMART SM00450 7 101 1.1E-18 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS08955 30cfed7e42488f510263cc2eacbca0ed 163 Pfam PF10263 SprT-like family 10 155 8.5E-29 T 13-09-2016 IPR006640 SprT-like THL1_RS08955 30cfed7e42488f510263cc2eacbca0ed 163 PANTHER PTHR38773 1 163 1.1E-77 T 13-09-2016 THL1_RS08955 30cfed7e42488f510263cc2eacbca0ed 163 SMART SM00731 7 157 5.5E-50 T 13-09-2016 IPR006640 SprT-like THL1_RS08955 30cfed7e42488f510263cc2eacbca0ed 163 Hamap MF_00746 Protein SprT [sprT]. 3 157 37.259 T 13-09-2016 IPR023483 Uncharacterised protein family SprT THL1_RS06505 8cb3b205899cf924849a5fb5f48c3c2d 403 Gene3D G3DSA:3.20.20.70 6 397 1.5E-92 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS06505 8cb3b205899cf924849a5fb5f48c3c2d 403 PANTHER PTHR22893 300 398 4.8E-116 T 13-09-2016 THL1_RS06505 8cb3b205899cf924849a5fb5f48c3c2d 403 PANTHER PTHR22893 8 270 4.8E-116 T 13-09-2016 THL1_RS06505 8cb3b205899cf924849a5fb5f48c3c2d 403 PANTHER PTHR22893:SF53 300 398 4.8E-116 T 13-09-2016 THL1_RS06505 8cb3b205899cf924849a5fb5f48c3c2d 403 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 256 8.4E-42 T 13-09-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 THL1_RS06505 8cb3b205899cf924849a5fb5f48c3c2d 403 SUPERFAMILY SSF51395 303 397 3.38E-90 T 13-09-2016 THL1_RS06505 8cb3b205899cf924849a5fb5f48c3c2d 403 SUPERFAMILY SSF51395 4 267 3.38E-90 T 13-09-2016 THL1_RS06505 8cb3b205899cf924849a5fb5f48c3c2d 403 PANTHER PTHR22893:SF53 8 270 4.8E-116 T 13-09-2016 THL1_RS18415 af343842b28fb6c8578992560cefc0bb 607 PANTHER PTHR24096 35 607 3.3E-231 T 13-09-2016 THL1_RS18415 af343842b28fb6c8578992560cefc0bb 607 PANTHER PTHR24096:SF192 35 607 3.3E-231 T 13-09-2016 IPR030310 Long-chain-fatty-acid--CoA ligase FadD17 GO:0004467|GO:0006633 THL1_RS18415 af343842b28fb6c8578992560cefc0bb 607 Gene3D G3DSA:3.30.300.30 475 571 6.1E-16 T 13-09-2016 THL1_RS18415 af343842b28fb6c8578992560cefc0bb 607 Gene3D G3DSA:2.30.38.10 402 455 1.2E-4 T 13-09-2016 THL1_RS18415 af343842b28fb6c8578992560cefc0bb 607 Gene3D G3DSA:3.40.50.980 220 366 1.1E-23 T 13-09-2016 THL1_RS18415 af343842b28fb6c8578992560cefc0bb 607 Pfam PF13193 AMP-binding enzyme C-terminal domain 483 559 1.6E-11 T 13-09-2016 IPR025110 AMP-binding enzyme C-terminal domain THL1_RS18415 af343842b28fb6c8578992560cefc0bb 607 Pfam PF00501 AMP-binding enzyme 48 474 2.1E-60 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS18415 af343842b28fb6c8578992560cefc0bb 607 SUPERFAMILY SSF56801 30 572 1.96E-100 T 13-09-2016 THL1_RS18415 af343842b28fb6c8578992560cefc0bb 607 ProSitePatterns PS00455 Putative AMP-binding domain signature. 214 225 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS18415 af343842b28fb6c8578992560cefc0bb 607 Gene3D G3DSA:3.40.50.980 44 219 6.7E-32 T 13-09-2016 THL1_RS09670 63e9b6fcade4a436802d1228c504fb0d 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 75 4.5E-16 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS09670 63e9b6fcade4a436802d1228c504fb0d 314 PANTHER PTHR30126:SF3 13 310 2.2E-133 T 13-09-2016 THL1_RS09670 63e9b6fcade4a436802d1228c504fb0d 314 Gene3D G3DSA:3.40.190.10 102 190 7.7E-14 T 13-09-2016 THL1_RS09670 63e9b6fcade4a436802d1228c504fb0d 314 Pfam PF03466 LysR substrate binding domain 103 308 7.0E-37 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS09670 63e9b6fcade4a436802d1228c504fb0d 314 PANTHER PTHR30126 13 310 2.2E-133 T 13-09-2016 THL1_RS09670 63e9b6fcade4a436802d1228c504fb0d 314 SUPERFAMILY SSF46785 13 123 3.1E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09670 63e9b6fcade4a436802d1228c504fb0d 314 Gene3D G3DSA:1.10.10.10 14 99 4.7E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09670 63e9b6fcade4a436802d1228c504fb0d 314 SUPERFAMILY SSF53850 104 307 3.8E-38 T 13-09-2016 THL1_RS09670 63e9b6fcade4a436802d1228c504fb0d 314 Gene3D G3DSA:3.40.190.10 191 276 1.4E-14 T 13-09-2016 THL1_RS20270 dd22e53be82e891e54128828f3d6aebe 308 SUPERFAMILY SSF52540 1 219 3.29E-66 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS20270 dd22e53be82e891e54128828f3d6aebe 308 SMART SM00382 25 206 5.0E-17 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS20270 dd22e53be82e891e54128828f3d6aebe 308 Pfam PF00005 ABC transporter 17 160 7.5E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS20270 dd22e53be82e891e54128828f3d6aebe 308 PANTHER PTHR24220:SF0 2 219 4.6E-102 T 13-09-2016 THL1_RS20270 dd22e53be82e891e54128828f3d6aebe 308 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS20270 dd22e53be82e891e54128828f3d6aebe 308 Gene3D G3DSA:3.40.50.300 1 219 6.2E-74 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS20270 dd22e53be82e891e54128828f3d6aebe 308 PANTHER PTHR24220 2 219 4.6E-102 T 13-09-2016 THL1_RS03910 a03cfe70ced018519d04b357f0767c36 302 Pfam PF01569 PAP2 superfamily 52 163 1.9E-19 T 13-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THL1_RS03910 a03cfe70ced018519d04b357f0767c36 302 SUPERFAMILY SSF48317 9 168 3.4E-23 T 13-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THL1_RS03910 a03cfe70ced018519d04b357f0767c36 302 PANTHER PTHR14969 14 157 1.2E-25 T 13-09-2016 THL1_RS03910 a03cfe70ced018519d04b357f0767c36 302 SMART SM00014 52 158 2.9E-14 T 13-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THL1_RS03910 a03cfe70ced018519d04b357f0767c36 302 Gene3D G3DSA:1.20.144.10 16 162 8.6E-18 T 13-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THL1_RS03910 a03cfe70ced018519d04b357f0767c36 302 PANTHER PTHR14969:SF3 14 157 1.2E-25 T 13-09-2016 THL1_RS16150 679c77923e27b2f9f3139ca8a3056f1b 188 TIGRFAM TIGR01644 phage_P2_V: phage baseplate assembly protein V 7 187 2.0E-51 T 13-09-2016 IPR013046 Phage baseplate assembly protein V/Gp45 THL1_RS16150 679c77923e27b2f9f3139ca8a3056f1b 188 Pfam PF04717 Type VI secretion system, phage-baseplate injector 5 116 4.4E-46 T 13-09-2016 IPR006531 Gp5 N-terminal THL1_RS23675 0032453d43df6d8a8a42312e0d79fbd7 301 SMART SM00563 89 231 1.1E-18 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS23675 0032453d43df6d8a8a42312e0d79fbd7 301 SUPERFAMILY SSF69593 16 294 9.29E-36 T 13-09-2016 THL1_RS23675 0032453d43df6d8a8a42312e0d79fbd7 301 Gene3D G3DSA:3.40.1130.10 66 190 1.2E-5 T 13-09-2016 THL1_RS23675 0032453d43df6d8a8a42312e0d79fbd7 301 PANTHER PTHR10983:SF15 1 297 6.4E-129 T 13-09-2016 THL1_RS23675 0032453d43df6d8a8a42312e0d79fbd7 301 PANTHER PTHR10983 1 297 6.4E-129 T 13-09-2016 THL1_RS23675 0032453d43df6d8a8a42312e0d79fbd7 301 Pfam PF01553 Acyltransferase 79 216 3.8E-14 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS10215 5778f0143e1ef073d9a825418c2fff2b 678 Gene3D G3DSA:3.50.50.60 474 631 7.5E-50 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10215 5778f0143e1ef073d9a825418c2fff2b 678 Gene3D G3DSA:3.50.50.60 364 469 3.7E-27 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10215 5778f0143e1ef073d9a825418c2fff2b 678 Gene3D G3DSA:3.20.20.70 6 363 9.0E-123 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS10215 5778f0143e1ef073d9a825418c2fff2b 678 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 462 480 3.1E-16 T 13-09-2016 THL1_RS10215 5778f0143e1ef073d9a825418c2fff2b 678 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 502 520 3.1E-16 T 13-09-2016 THL1_RS10215 5778f0143e1ef073d9a825418c2fff2b 678 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 624 640 3.1E-16 T 13-09-2016 THL1_RS10215 5778f0143e1ef073d9a825418c2fff2b 678 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 380 399 3.1E-16 T 13-09-2016 THL1_RS10215 5778f0143e1ef073d9a825418c2fff2b 678 PANTHER PTHR22893:SF25 1 420 9.2E-247 T 13-09-2016 THL1_RS10215 5778f0143e1ef073d9a825418c2fff2b 678 SUPERFAMILY SSF51971 336 526 8.47E-43 T 13-09-2016 THL1_RS10215 5778f0143e1ef073d9a825418c2fff2b 678 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 625 639 5.0E-6 T 13-09-2016 THL1_RS10215 5778f0143e1ef073d9a825418c2fff2b 678 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 379 401 5.0E-6 T 13-09-2016 THL1_RS10215 5778f0143e1ef073d9a825418c2fff2b 678 SUPERFAMILY SSF51905 465 523 9.5E-19 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10215 5778f0143e1ef073d9a825418c2fff2b 678 SUPERFAMILY SSF51905 561 656 9.5E-19 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10215 5778f0143e1ef073d9a825418c2fff2b 678 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 9 334 1.7E-85 T 13-09-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 THL1_RS10215 5778f0143e1ef073d9a825418c2fff2b 678 PANTHER PTHR22893 1 420 9.2E-247 T 13-09-2016 THL1_RS10215 5778f0143e1ef073d9a825418c2fff2b 678 SUPERFAMILY SSF51395 4 365 6.2E-111 T 13-09-2016 THL1_RS10215 5778f0143e1ef073d9a825418c2fff2b 678 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 378 651 1.4E-22 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS28405 daf6f68e5a5cadd9568695e936d02cf4 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 41 59 1.0E-6 T 13-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 THL1_RS28405 daf6f68e5a5cadd9568695e936d02cf4 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 27 41 1.0E-6 T 13-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 THL1_RS28405 daf6f68e5a5cadd9568695e936d02cf4 255 PANTHER PTHR30363:SF15 3 252 2.4E-149 T 13-09-2016 THL1_RS28405 daf6f68e5a5cadd9568695e936d02cf4 255 PANTHER PTHR30363 3 252 2.4E-149 T 13-09-2016 THL1_RS28405 daf6f68e5a5cadd9568695e936d02cf4 255 SMART SM01134 72 233 5.7E-58 T 13-09-2016 THL1_RS28405 daf6f68e5a5cadd9568695e936d02cf4 255 SUPERFAMILY SSF100950 76 233 6.7E-32 T 13-09-2016 THL1_RS28405 daf6f68e5a5cadd9568695e936d02cf4 255 Gene3D G3DSA:3.40.50.1360 75 221 8.5E-16 T 13-09-2016 THL1_RS28405 daf6f68e5a5cadd9568695e936d02cf4 255 Gene3D G3DSA:1.10.10.10 7 58 5.6E-10 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS28405 daf6f68e5a5cadd9568695e936d02cf4 255 ProSitePatterns PS00894 DeoR-type HTH domain signature. 9 43 - T 13-09-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 THL1_RS28405 daf6f68e5a5cadd9568695e936d02cf4 255 Pfam PF00455 DeoR C terminal sensor domain 77 232 5.9E-44 T 13-09-2016 IPR014036 DeoR C-terminal sensor domain THL1_RS28405 daf6f68e5a5cadd9568695e936d02cf4 255 SMART SM00420 9 61 2.6E-15 T 13-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 THL1_RS28405 daf6f68e5a5cadd9568695e936d02cf4 255 Pfam PF08220 DeoR-like helix-turn-helix domain 9 60 5.1E-16 T 13-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 THL1_RS28405 daf6f68e5a5cadd9568695e936d02cf4 255 SUPERFAMILY SSF46785 7 64 1.24E-13 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS04660 e14b584e8d68ebf7a235951b74ecd2b3 335 PIRSF PIRSF000267 2 335 5.1E-94 T 13-09-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 THL1_RS04660 e14b584e8d68ebf7a235951b74ecd2b3 335 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 5 324 5.4E-103 T 13-09-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 THL1_RS04660 e14b584e8d68ebf7a235951b74ecd2b3 335 PANTHER PTHR30365:SF4 1 335 5.3E-184 T 13-09-2016 THL1_RS04660 e14b584e8d68ebf7a235951b74ecd2b3 335 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 5 332 2.5E-53 T 13-09-2016 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 THL1_RS04660 e14b584e8d68ebf7a235951b74ecd2b3 335 PANTHER PTHR30365 1 335 5.3E-184 T 13-09-2016 THL1_RS14570 bc62047695a4694f6b8a8d19fe422331 302 Gene3D G3DSA:3.60.110.10 4 285 1.0E-94 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS14570 bc62047695a4694f6b8a8d19fe422331 302 SUPERFAMILY SSF56317 1 285 1.02E-85 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS14570 bc62047695a4694f6b8a8d19fe422331 302 PANTHER PTHR23088 1 288 1.9E-138 T 13-09-2016 THL1_RS14570 bc62047695a4694f6b8a8d19fe422331 302 PANTHER PTHR23088:SF11 1 288 1.9E-138 T 13-09-2016 THL1_RS14570 bc62047695a4694f6b8a8d19fe422331 302 Pfam PF00795 Carbon-nitrogen hydrolase 6 266 7.8E-56 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS14570 bc62047695a4694f6b8a8d19fe422331 302 TIGRFAM TIGR03381 agmatine_aguB: N-carbamoylputrescine amidase 4 284 2.7E-137 T 13-09-2016 IPR017755 N-carbamoylputrescine amidase GO:0006596|GO:0050126 KEGG: 00330+3.5.1.53|MetaCyc: PWY-43|UniPathway: UPA00534 THL1_RS15700 9eddee1b865e4b64bbca0dd5772f7de8 263 Gene3D G3DSA:3.90.226.10 1 203 2.9E-67 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS15700 9eddee1b865e4b64bbca0dd5772f7de8 263 SUPERFAMILY SSF52096 1 263 8.24E-85 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS15700 9eddee1b865e4b64bbca0dd5772f7de8 263 PANTHER PTHR11941:SF76 2 260 2.0E-109 T 13-09-2016 THL1_RS15700 9eddee1b865e4b64bbca0dd5772f7de8 263 TIGRFAM TIGR02280 PaaB1: phenylacetate degradation probable enoyl-CoA hydratase PaaB 6 263 8.3E-127 T 13-09-2016 IPR011968 Phenylacetate degradation probable enoyl-CoA hydratase PaaB GO:0010124 KEGG: 00360+5.3.3.18|UniPathway: UPA00930 THL1_RS15700 9eddee1b865e4b64bbca0dd5772f7de8 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 262 6.2E-66 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS15700 9eddee1b865e4b64bbca0dd5772f7de8 263 PANTHER PTHR11941 2 260 2.0E-109 T 13-09-2016 THL1_RS15700 9eddee1b865e4b64bbca0dd5772f7de8 263 Gene3D G3DSA:1.10.12.10 205 263 9.0E-21 T 13-09-2016 IPR014748 Crontonase, C-terminal THL1_RS21870 7c8c62c8edce85d1979bea91e8d2d8f7 553 SUPERFAMILY SSF51905 472 533 2.59E-91 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21870 7c8c62c8edce85d1979bea91e8d2d8f7 553 SUPERFAMILY SSF51905 3 289 2.59E-91 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21870 7c8c62c8edce85d1979bea91e8d2d8f7 553 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 83 106 - T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS21870 7c8c62c8edce85d1979bea91e8d2d8f7 553 PIRSF PIRSF000137 1 536 1.3E-145 T 13-09-2016 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|UniPathway: UPA00529 THL1_RS21870 7c8c62c8edce85d1979bea91e8d2d8f7 553 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 255 269 - T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS21870 7c8c62c8edce85d1979bea91e8d2d8f7 553 Gene3D G3DSA:3.50.50.60 188 314 1.1E-123 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21870 7c8c62c8edce85d1979bea91e8d2d8f7 553 Gene3D G3DSA:3.50.50.60 466 531 1.1E-123 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21870 7c8c62c8edce85d1979bea91e8d2d8f7 553 Gene3D G3DSA:3.50.50.60 3 127 1.1E-123 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21870 7c8c62c8edce85d1979bea91e8d2d8f7 553 Pfam PF00732 GMC oxidoreductase 6 296 3.0E-90 T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS21870 7c8c62c8edce85d1979bea91e8d2d8f7 553 SUPERFAMILY SSF54373 292 473 2.45E-53 T 13-09-2016 THL1_RS21870 7c8c62c8edce85d1979bea91e8d2d8f7 553 Pfam PF05199 GMC oxidoreductase 387 525 1.3E-40 T 13-09-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 THL1_RS21870 7c8c62c8edce85d1979bea91e8d2d8f7 553 PANTHER PTHR11552 5 551 6.3E-240 T 13-09-2016 THL1_RS21870 7c8c62c8edce85d1979bea91e8d2d8f7 553 PANTHER PTHR11552:SF51 5 551 6.3E-240 T 13-09-2016 THL1_RS07595 25c1c9073ca9ec3944040d6dae19e1b4 302 PANTHER PTHR30193 1 300 9.2E-147 T 13-09-2016 THL1_RS07595 25c1c9073ca9ec3944040d6dae19e1b4 302 Gene3D G3DSA:1.10.3720.10 68 293 1.2E-51 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07595 25c1c9073ca9ec3944040d6dae19e1b4 302 SUPERFAMILY SSF161098 62 288 2.22E-48 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07595 25c1c9073ca9ec3944040d6dae19e1b4 302 PANTHER PTHR30193:SF29 1 300 9.2E-147 T 13-09-2016 THL1_RS07595 25c1c9073ca9ec3944040d6dae19e1b4 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 295 4.4E-13 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS21805 95a5cffd6ae0e8986662ea4b59ab45f3 394 SUPERFAMILY SSF56645 5 207 2.09E-35 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS21805 95a5cffd6ae0e8986662ea4b59ab45f3 394 Gene3D G3DSA:2.40.110.10 115 204 5.3E-30 T 13-09-2016 THL1_RS21805 95a5cffd6ae0e8986662ea4b59ab45f3 394 PANTHER PTHR10909 15 368 1.9E-41 T 13-09-2016 THL1_RS21805 95a5cffd6ae0e8986662ea4b59ab45f3 394 PANTHER PTHR10909:SF275 15 368 1.9E-41 T 13-09-2016 THL1_RS21805 95a5cffd6ae0e8986662ea4b59ab45f3 394 Gene3D G3DSA:1.10.540.10 9 110 1.5E-34 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS21805 95a5cffd6ae0e8986662ea4b59ab45f3 394 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 243 371 6.6E-27 T 13-09-2016 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain THL1_RS21805 95a5cffd6ae0e8986662ea4b59ab45f3 394 Gene3D G3DSA:1.20.140.10 205 388 1.4E-35 T 13-09-2016 THL1_RS21805 95a5cffd6ae0e8986662ea4b59ab45f3 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 3 88 9.3E-5 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS21805 95a5cffd6ae0e8986662ea4b59ab45f3 394 SUPERFAMILY SSF47203 241 368 2.66E-9 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS21805 95a5cffd6ae0e8986662ea4b59ab45f3 394 PIRSF PIRSF016578 3 392 1.9E-117 T 13-09-2016 THL1_RS07570 d6fc7faefa94a43ec56a638e3f0cdf59 608 PANTHER PTHR21000 1 597 0.0 T 13-09-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS07570 d6fc7faefa94a43ec56a638e3f0cdf59 608 SUPERFAMILY SSF52016 419 600 9.42E-58 T 13-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THL1_RS07570 d6fc7faefa94a43ec56a638e3f0cdf59 608 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 505 516 - T 13-09-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS07570 d6fc7faefa94a43ec56a638e3f0cdf59 608 Pfam PF00920 Dehydratase family 67 597 8.1E-163 T 13-09-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS07570 d6fc7faefa94a43ec56a638e3f0cdf59 608 SUPERFAMILY SSF143975 1 418 3.4E-148 T 13-09-2016 THL1_RS07570 d6fc7faefa94a43ec56a638e3f0cdf59 608 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 2 601 0.0 T 13-09-2016 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12|UniPathway: UPA00226 THL1_RS07570 d6fc7faefa94a43ec56a638e3f0cdf59 608 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 154 164 - T 13-09-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS07570 d6fc7faefa94a43ec56a638e3f0cdf59 608 PANTHER PTHR21000:SF9 1 597 0.0 T 13-09-2016 THL1_RS16340 6eda8bce5011ffee643bbd22194507aa 311 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 1 310 47.965 T 13-09-2016 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 THL1_RS16340 6eda8bce5011ffee643bbd22194507aa 311 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 76 94 - T 13-09-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 THL1_RS16340 6eda8bce5011ffee643bbd22194507aa 311 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 1 308 4.4E-135 T 13-09-2016 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 THL1_RS16340 6eda8bce5011ffee643bbd22194507aa 311 PIRSF PIRSF006621 1 310 6.5E-73 T 13-09-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 THL1_RS16340 6eda8bce5011ffee643bbd22194507aa 311 Gene3D G3DSA:3.20.20.70 1 236 2.6E-70 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS16340 6eda8bce5011ffee643bbd22194507aa 311 SUPERFAMILY SSF51395 1 304 1.43E-72 T 13-09-2016 THL1_RS16340 6eda8bce5011ffee643bbd22194507aa 311 PANTHER PTHR11082 1 308 1.4E-138 T 13-09-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 THL1_RS16340 6eda8bce5011ffee643bbd22194507aa 311 PANTHER PTHR11082:SF29 1 308 1.4E-138 T 13-09-2016 THL1_RS16340 6eda8bce5011ffee643bbd22194507aa 311 Pfam PF01207 Dihydrouridine synthase (Dus) 1 303 4.5E-84 T 13-09-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 THL1_RS21390 bf033f8015a90df911e1874f6e1db302 503 PANTHER PTHR35342 2 503 2.2E-270 T 13-09-2016 THL1_RS21390 bf033f8015a90df911e1874f6e1db302 503 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 440 1.8E-143 T 13-09-2016 IPR002823 Protein of unknown function DUF112, transmembrane THL1_RS21390 bf033f8015a90df911e1874f6e1db302 503 PANTHER PTHR35342:SF4 2 503 2.2E-270 T 13-09-2016 THL1_RS04230 395dcd6a82d229a803466d3c71489ec4 632 PANTHER PTHR30627 5 631 4.8E-251 T 13-09-2016 THL1_RS04230 395dcd6a82d229a803466d3c71489ec4 632 SUPERFAMILY SSF56601 251 607 1.54E-98 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS04230 395dcd6a82d229a803466d3c71489ec4 632 PANTHER PTHR30627:SF2 5 631 4.8E-251 T 13-09-2016 THL1_RS04230 395dcd6a82d229a803466d3c71489ec4 632 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 19 607 2.4E-237 T 13-09-2016 IPR017790 Penicillin-binding protein 2 GO:0016020 UniPathway: UPA00219 THL1_RS04230 395dcd6a82d229a803466d3c71489ec4 632 Pfam PF00905 Penicillin binding protein transpeptidase domain 268 604 4.7E-73 T 13-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THL1_RS04230 395dcd6a82d229a803466d3c71489ec4 632 Gene3D G3DSA:3.90.1310.10 131 249 1.8E-39 T 13-09-2016 THL1_RS04230 395dcd6a82d229a803466d3c71489ec4 632 SUPERFAMILY SSF56519 56 250 1.7E-52 T 13-09-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 THL1_RS04230 395dcd6a82d229a803466d3c71489ec4 632 Gene3D G3DSA:3.40.710.10 250 607 9.3E-108 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS04230 395dcd6a82d229a803466d3c71489ec4 632 Pfam PF03717 Penicillin-binding Protein dimerisation domain 64 236 5.2E-44 T 13-09-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 THL1_RS14060 d9e7748c4d3290b9297a8f1a63acd22b 323 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 230 322 3.5E-18 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS14060 d9e7748c4d3290b9297a8f1a63acd22b 323 SUPERFAMILY SSF52540 6 192 3.82E-34 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14060 d9e7748c4d3290b9297a8f1a63acd22b 323 SUPERFAMILY SSF90002 230 322 1.57E-14 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS14060 d9e7748c4d3290b9297a8f1a63acd22b 323 SMART SM00833 230 322 3.0E-13 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS14060 d9e7748c4d3290b9297a8f1a63acd22b 323 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 8 173 5.0E-49 T 13-09-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain THL1_RS14060 d9e7748c4d3290b9297a8f1a63acd22b 323 PANTHER PTHR13748 2 323 2.7E-93 T 13-09-2016 THL1_RS14060 d9e7748c4d3290b9297a8f1a63acd22b 323 Gene3D G3DSA:3.30.1220.10 224 323 1.1E-18 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS14060 d9e7748c4d3290b9297a8f1a63acd22b 323 Gene3D G3DSA:3.40.50.300 6 201 6.3E-65 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11720 6e455a19724835f37dc4a9fcdaff9102 268 PIRSF PIRSF005902 1 267 4.5E-64 T 13-09-2016 IPR001130 TatD family GO:0016788 THL1_RS11720 6e455a19724835f37dc4a9fcdaff9102 268 PANTHER PTHR10060 1 266 1.4E-146 T 13-09-2016 IPR001130 TatD family GO:0016788 THL1_RS11720 6e455a19724835f37dc4a9fcdaff9102 268 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 129 139 - T 13-09-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 THL1_RS11720 6e455a19724835f37dc4a9fcdaff9102 268 Pfam PF01026 TatD related DNase 4 262 2.5E-60 T 13-09-2016 IPR001130 TatD family GO:0016788 THL1_RS11720 6e455a19724835f37dc4a9fcdaff9102 268 PANTHER PTHR10060:SF13 1 266 1.4E-146 T 13-09-2016 THL1_RS11720 6e455a19724835f37dc4a9fcdaff9102 268 SUPERFAMILY SSF51556 3 264 4.47E-75 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS11720 6e455a19724835f37dc4a9fcdaff9102 268 Gene3D G3DSA:3.20.20.140 1 264 1.7E-80 T 13-09-2016 THL1_RS03030 987c5adc0de2ff705f9729bd00150ebc 463 PANTHER PTHR30576:SF0 18 458 4.0E-137 T 13-09-2016 THL1_RS03030 987c5adc0de2ff705f9729bd00150ebc 463 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 25 459 7.7E-139 T 13-09-2016 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 THL1_RS03030 987c5adc0de2ff705f9729bd00150ebc 463 Pfam PF02397 Bacterial sugar transferase 275 458 1.6E-57 T 13-09-2016 IPR003362 Bacterial sugar transferase THL1_RS03030 987c5adc0de2ff705f9729bd00150ebc 463 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 26 460 4.2E-137 T 13-09-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase THL1_RS03030 987c5adc0de2ff705f9729bd00150ebc 463 PANTHER PTHR30576 18 458 4.0E-137 T 13-09-2016 THL1_RS03030 987c5adc0de2ff705f9729bd00150ebc 463 Pfam PF13727 CoA-binding domain 76 237 2.4E-22 T 13-09-2016 THL1_RS09660 823b1af3bec64e2b1fda3503d70c35d9 1325 Pfam PF00171 Aldehyde dehydrogenase family 662 1105 1.8E-116 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS09660 823b1af3bec64e2b1fda3503d70c35d9 1325 PANTHER PTHR11699:SF18 659 1107 1.4E-178 T 13-09-2016 THL1_RS09660 823b1af3bec64e2b1fda3503d70c35d9 1325 SUPERFAMILY SSF81935 90 263 6.02E-66 T 13-09-2016 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922|UniPathway: UPA00261|UniPathway: UPA00261 THL1_RS09660 823b1af3bec64e2b1fda3503d70c35d9 1325 SUPERFAMILY SSF51730 264 619 8.63E-121 T 13-09-2016 IPR029041 FAD-linked oxidoreductase-like THL1_RS09660 823b1af3bec64e2b1fda3503d70c35d9 1325 Gene3D G3DSA:3.40.309.10 900 1089 3.5E-48 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS09660 823b1af3bec64e2b1fda3503d70c35d9 1325 SUPERFAMILY SSF53720 658 1112 2.36E-129 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS09660 823b1af3bec64e2b1fda3503d70c35d9 1325 Pfam PF01619 Proline dehydrogenase 273 571 6.1E-98 T 13-09-2016 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|UniPathway: UPA00261 THL1_RS09660 823b1af3bec64e2b1fda3503d70c35d9 1325 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 912 923 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS09660 823b1af3bec64e2b1fda3503d70c35d9 1325 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 613 1112 2.5E-242 T 13-09-2016 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922|UniPathway: UPA00261|UniPathway: UPA00261 THL1_RS09660 823b1af3bec64e2b1fda3503d70c35d9 1325 Gene3D G3DSA:3.20.20.220 263 618 2.0E-118 T 13-09-2016 IPR029041 FAD-linked oxidoreductase-like THL1_RS09660 823b1af3bec64e2b1fda3503d70c35d9 1325 SUPERFAMILY SSF47598 5 46 2.22E-9 T 13-09-2016 IPR010985 Ribbon-helix-helix GO:0006355 THL1_RS09660 823b1af3bec64e2b1fda3503d70c35d9 1325 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 150 261 7.0E-46 T 13-09-2016 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922|UniPathway: UPA00261|UniPathway: UPA00261 THL1_RS09660 823b1af3bec64e2b1fda3503d70c35d9 1325 PANTHER PTHR11699 659 1107 1.4E-178 T 13-09-2016 THL1_RS09660 823b1af3bec64e2b1fda3503d70c35d9 1325 Gene3D G3DSA:1.20.5.550 89 140 5.4E-25 T 13-09-2016 IPR024090 Proline dehydrogenase PutA, domain I GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922|UniPathway: UPA00261|UniPathway: UPA00261 THL1_RS09660 823b1af3bec64e2b1fda3503d70c35d9 1325 PIRSF PIRSF000197 76 1325 0.0 T 13-09-2016 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922|UniPathway: UPA00261|UniPathway: UPA00261 THL1_RS09660 823b1af3bec64e2b1fda3503d70c35d9 1325 Gene3D G3DSA:3.40.605.10 659 899 1.3E-68 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS09660 823b1af3bec64e2b1fda3503d70c35d9 1325 Gene3D G3DSA:1.10.2060.10 146 262 8.1E-54 T 13-09-2016 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922|UniPathway: UPA00261|UniPathway: UPA00261 THL1_RS20230 09ac9e91d94cdc1f84562aecd05b6303 245 SMART SM00062 23 245 0.0023 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS20230 09ac9e91d94cdc1f84562aecd05b6303 245 Gene3D G3DSA:3.40.190.10 43 123 1.8E-10 T 13-09-2016 THL1_RS20230 09ac9e91d94cdc1f84562aecd05b6303 245 Gene3D G3DSA:3.40.190.10 124 185 1.1E-5 T 13-09-2016 THL1_RS20230 09ac9e91d94cdc1f84562aecd05b6303 245 SUPERFAMILY SSF53850 23 239 8.15E-32 T 13-09-2016 THL1_RS20230 09ac9e91d94cdc1f84562aecd05b6303 245 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 25 239 6.8E-18 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS20230 09ac9e91d94cdc1f84562aecd05b6303 245 PANTHER PTHR35936:SF3 6 239 2.4E-37 T 13-09-2016 THL1_RS20230 09ac9e91d94cdc1f84562aecd05b6303 245 PANTHER PTHR35936 6 239 2.4E-37 T 13-09-2016 THL1_RS08180 d0e187ce5c9ecf65acd6e3d026cde962 763 Pfam PF02449 Beta-galactosidase 451 604 5.2E-6 T 13-09-2016 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 THL1_RS08180 d0e187ce5c9ecf65acd6e3d026cde962 763 Gene3D G3DSA:3.20.20.80 351 710 2.9E-26 T 13-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 THL1_RS08180 d0e187ce5c9ecf65acd6e3d026cde962 763 SUPERFAMILY SSF51445 364 708 4.65E-33 T 13-09-2016 IPR017853 Glycoside hydrolase superfamily THL1_RS17175 efd2abb498da93184faeaac33a0b3e37 456 SUPERFAMILY SSF51905 42 265 3.04E-41 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS17175 efd2abb498da93184faeaac33a0b3e37 456 SUPERFAMILY SSF51905 364 415 3.04E-41 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS17175 efd2abb498da93184faeaac33a0b3e37 456 Pfam PF01266 FAD dependent oxidoreductase 43 403 1.9E-53 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS17175 efd2abb498da93184faeaac33a0b3e37 456 PANTHER PTHR13847:SF196 33 406 1.2E-60 T 13-09-2016 THL1_RS17175 efd2abb498da93184faeaac33a0b3e37 456 Gene3D G3DSA:3.50.50.60 364 416 2.9E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS17175 efd2abb498da93184faeaac33a0b3e37 456 Gene3D G3DSA:3.50.50.60 185 264 2.9E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS17175 efd2abb498da93184faeaac33a0b3e37 456 Gene3D G3DSA:3.50.50.60 33 132 2.9E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS17175 efd2abb498da93184faeaac33a0b3e37 456 PANTHER PTHR13847 33 406 1.2E-60 T 13-09-2016 THL1_RS10870 383229c68239f7b891fb1853d943c155 943 PANTHER PTHR23152:SF4 1 943 0.0 T 13-09-2016 THL1_RS10870 383229c68239f7b891fb1853d943c155 943 PANTHER PTHR23152 1 943 0.0 T 13-09-2016 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 THL1_RS10870 383229c68239f7b891fb1853d943c155 943 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 797 941 4.5E-54 T 13-09-2016 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 THL1_RS10870 383229c68239f7b891fb1853d943c155 943 Gene3D G3DSA:3.40.50.970 166 541 1.5E-78 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS10870 383229c68239f7b891fb1853d943c155 943 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 15 941 0.0 T 13-09-2016 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 THL1_RS10870 383229c68239f7b891fb1853d943c155 943 SUPERFAMILY SSF52518 582 799 2.02E-50 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS10870 383229c68239f7b891fb1853d943c155 943 SMART SM00861 599 792 5.7E-57 T 13-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain THL1_RS10870 383229c68239f7b891fb1853d943c155 943 SUPERFAMILY SSF52518 126 550 1.4E-87 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS10870 383229c68239f7b891fb1853d943c155 943 Pfam PF02779 Transketolase, pyrimidine binding domain 598 793 5.1E-64 T 13-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain THL1_RS10870 383229c68239f7b891fb1853d943c155 943 Pfam PF00676 Dehydrogenase E1 component 219 526 1.6E-51 T 13-09-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 THL1_RS10870 383229c68239f7b891fb1853d943c155 943 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 12 49 3.8E-17 T 13-09-2016 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 THL1_RS10870 383229c68239f7b891fb1853d943c155 943 PIRSF PIRSF000157 1 943 0.0 T 13-09-2016 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 THL1_RS10870 383229c68239f7b891fb1853d943c155 943 Gene3D G3DSA:3.40.50.970 599 801 1.1E-22 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS20765 144cf197c95ff67e5f5130034d3a1941 551 Gene3D G3DSA:3.40.50.300 1 325 2.6E-17 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS20765 144cf197c95ff67e5f5130034d3a1941 551 SUPERFAMILY SSF52540 1 311 7.14E-12 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS20765 144cf197c95ff67e5f5130034d3a1941 551 Pfam PF13175 AAA ATPase domain 1 307 6.6E-24 T 13-09-2016 THL1_RS11295 d80116536dd54131932b1e0ffd2c618e 274 PANTHER PTHR30193 16 274 1.1E-71 T 13-09-2016 THL1_RS11295 d80116536dd54131932b1e0ffd2c618e 274 PANTHER PTHR30193:SF20 16 274 1.1E-71 T 13-09-2016 THL1_RS11295 d80116536dd54131932b1e0ffd2c618e 274 Gene3D G3DSA:1.10.3720.10 16 264 9.0E-47 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS11295 d80116536dd54131932b1e0ffd2c618e 274 SUPERFAMILY SSF161098 11 267 1.44E-48 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS11295 d80116536dd54131932b1e0ffd2c618e 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 255 4.3E-15 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS12485 3edfd7c8f68964adcfbe20b73716e912 214 PANTHER PTHR26402:SF506 2 212 1.0E-96 T 13-09-2016 THL1_RS12485 3edfd7c8f68964adcfbe20b73716e912 214 SUPERFAMILY SSF46894 147 210 6.38E-15 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS12485 3edfd7c8f68964adcfbe20b73716e912 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS12485 3edfd7c8f68964adcfbe20b73716e912 214 SMART SM00448 2 115 3.9E-33 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS12485 3edfd7c8f68964adcfbe20b73716e912 214 Gene3D G3DSA:1.10.10.10 121 211 5.5E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12485 3edfd7c8f68964adcfbe20b73716e912 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 5.1E-5 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS12485 3edfd7c8f68964adcfbe20b73716e912 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 5.1E-5 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS12485 3edfd7c8f68964adcfbe20b73716e912 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 5.1E-5 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS12485 3edfd7c8f68964adcfbe20b73716e912 214 PANTHER PTHR26402 2 212 1.0E-96 T 13-09-2016 THL1_RS12485 3edfd7c8f68964adcfbe20b73716e912 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 4.3E-19 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS12485 3edfd7c8f68964adcfbe20b73716e912 214 SMART SM00421 147 204 5.5E-17 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS12485 3edfd7c8f68964adcfbe20b73716e912 214 Pfam PF00072 Response regulator receiver domain 4 116 6.9E-30 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS12485 3edfd7c8f68964adcfbe20b73716e912 214 Gene3D G3DSA:3.40.50.2300 2 120 1.8E-37 T 13-09-2016 THL1_RS12485 3edfd7c8f68964adcfbe20b73716e912 214 SUPERFAMILY SSF52172 2 162 5.12E-36 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS28195 80e0290d8c7a8cbbe23618265e041b93 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 9.5E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS28195 80e0290d8c7a8cbbe23618265e041b93 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 9.5E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS28195 80e0290d8c7a8cbbe23618265e041b93 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 9.5E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS28195 80e0290d8c7a8cbbe23618265e041b93 320 Pfam PF03466 LysR substrate binding domain 94 298 2.4E-51 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS28195 80e0290d8c7a8cbbe23618265e041b93 320 Gene3D G3DSA:1.10.10.10 8 94 3.4E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS28195 80e0290d8c7a8cbbe23618265e041b93 320 SUPERFAMILY SSF53850 96 302 3.26E-46 T 13-09-2016 THL1_RS28195 80e0290d8c7a8cbbe23618265e041b93 320 PANTHER PTHR30126 7 313 3.7E-139 T 13-09-2016 THL1_RS28195 80e0290d8c7a8cbbe23618265e041b93 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 69 7.8E-19 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS28195 80e0290d8c7a8cbbe23618265e041b93 320 Gene3D G3DSA:3.40.190.10 182 269 2.1E-23 T 13-09-2016 THL1_RS28195 80e0290d8c7a8cbbe23618265e041b93 320 PANTHER PTHR30126:SF5 7 313 3.7E-139 T 13-09-2016 THL1_RS28195 80e0290d8c7a8cbbe23618265e041b93 320 Gene3D G3DSA:3.40.190.10 97 181 7.0E-18 T 13-09-2016 THL1_RS28195 80e0290d8c7a8cbbe23618265e041b93 320 SUPERFAMILY SSF46785 6 85 1.09E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14325 ce072487b7a653a0ca4c236efb7b6f38 289 PANTHER PTHR42194:SF1 12 289 1.3E-55 T 13-09-2016 THL1_RS14325 ce072487b7a653a0ca4c236efb7b6f38 289 Pfam PF05114 Protein of unknown function (DUF692) 18 283 5.3E-105 T 13-09-2016 IPR007801 Uncharacterised protein family UPF0276 THL1_RS14325 ce072487b7a653a0ca4c236efb7b6f38 289 SUPERFAMILY SSF51658 65 222 8.35E-7 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS14325 ce072487b7a653a0ca4c236efb7b6f38 289 Hamap MF_00697 UPF0276 protein . 18 289 43.952 T 13-09-2016 IPR007801 Uncharacterised protein family UPF0276 THL1_RS14325 ce072487b7a653a0ca4c236efb7b6f38 289 Gene3D G3DSA:3.20.20.150 15 286 7.4E-100 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS14325 ce072487b7a653a0ca4c236efb7b6f38 289 PANTHER PTHR42194 12 289 1.3E-55 T 13-09-2016 THL1_RS01420 bdd4e3f190012db4d731cb85e53c9b1b 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 260 1.4E-16 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01420 bdd4e3f190012db4d731cb85e53c9b1b 262 Gene3D G3DSA:1.10.3720.10 13 261 8.1E-60 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01420 bdd4e3f190012db4d731cb85e53c9b1b 262 PANTHER PTHR30222:SF7 18 262 2.2E-156 T 13-09-2016 THL1_RS01420 bdd4e3f190012db4d731cb85e53c9b1b 262 SUPERFAMILY SSF161098 5 260 7.59E-58 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01420 bdd4e3f190012db4d731cb85e53c9b1b 262 PANTHER PTHR30222 18 262 2.2E-156 T 13-09-2016 THL1_RS01340 ef71aef51074e2938e267695a37f4c8a 342 SMART SM00342 255 336 7.8E-16 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS01340 ef71aef51074e2938e267695a37f4c8a 342 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 50 211 1.1E-34 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS01340 ef71aef51074e2938e267695a37f4c8a 342 PANTHER PTHR11019 211 341 8.5E-23 T 13-09-2016 THL1_RS01340 ef71aef51074e2938e267695a37f4c8a 342 Gene3D G3DSA:1.10.10.60 294 338 1.9E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01340 ef71aef51074e2938e267695a37f4c8a 342 Pfam PF12833 Helix-turn-helix domain 262 338 1.6E-15 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS01340 ef71aef51074e2938e267695a37f4c8a 342 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 320 336 3.6E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS01340 ef71aef51074e2938e267695a37f4c8a 342 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 305 320 3.6E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS01340 ef71aef51074e2938e267695a37f4c8a 342 PANTHER PTHR11019:SF52 211 341 8.5E-23 T 13-09-2016 THL1_RS01340 ef71aef51074e2938e267695a37f4c8a 342 SUPERFAMILY SSF46689 294 340 2.04E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS05295 2c761db34fa4ffa6e370554db245db8e 345 PANTHER PTHR19375 9 334 8.5E-184 T 13-09-2016 THL1_RS05295 2c761db34fa4ffa6e370554db245db8e 345 SUPERFAMILY SSF53067 151 339 5.68E-48 T 13-09-2016 THL1_RS05295 2c761db34fa4ffa6e370554db245db8e 345 Gene3D G3DSA:3.30.420.40 9 161 8.5E-47 T 13-09-2016 THL1_RS05295 2c761db34fa4ffa6e370554db245db8e 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 134 153 5.2E-65 T 13-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 THL1_RS05295 2c761db34fa4ffa6e370554db245db8e 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 70 93 5.2E-65 T 13-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 THL1_RS05295 2c761db34fa4ffa6e370554db245db8e 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 189 209 5.2E-65 T 13-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 THL1_RS05295 2c761db34fa4ffa6e370554db245db8e 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 302 328 5.2E-65 T 13-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 THL1_RS05295 2c761db34fa4ffa6e370554db245db8e 345 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 50 68 5.2E-65 T 13-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 THL1_RS05295 2c761db34fa4ffa6e370554db245db8e 345 SUPERFAMILY SSF53067 9 150 2.46E-38 T 13-09-2016 THL1_RS05295 2c761db34fa4ffa6e370554db245db8e 345 Gene3D G3DSA:3.30.420.40 265 319 3.8E-34 T 13-09-2016 THL1_RS05295 2c761db34fa4ffa6e370554db245db8e 345 Gene3D G3DSA:3.30.420.40 162 188 3.8E-34 T 13-09-2016 THL1_RS05295 2c761db34fa4ffa6e370554db245db8e 345 Pfam PF06723 MreB/Mbl protein 11 337 1.0E-148 T 13-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 THL1_RS05295 2c761db34fa4ffa6e370554db245db8e 345 Gene3D G3DSA:3.90.640.10 189 260 3.2E-28 T 13-09-2016 THL1_RS05295 2c761db34fa4ffa6e370554db245db8e 345 PANTHER PTHR19375:SF117 9 334 8.5E-184 T 13-09-2016 THL1_RS05295 2c761db34fa4ffa6e370554db245db8e 345 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 337 5.0E-161 T 13-09-2016 IPR004753 Cell shape determining protein MreB/Mrl GO:0000902 THL1_RS15890 ade87464690c434a31ed275628e9f782 264 PANTHER PTHR11941 1 261 3.3E-110 T 13-09-2016 THL1_RS15890 ade87464690c434a31ed275628e9f782 264 SUPERFAMILY SSF52096 2 263 3.66E-73 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS15890 ade87464690c434a31ed275628e9f782 264 Gene3D G3DSA:3.90.226.10 5 204 9.4E-56 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS15890 ade87464690c434a31ed275628e9f782 264 PANTHER PTHR11941:SF86 1 261 3.3E-110 T 13-09-2016 THL1_RS15890 ade87464690c434a31ed275628e9f782 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 264 2.5E-50 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS15890 ade87464690c434a31ed275628e9f782 264 Gene3D G3DSA:1.10.12.10 206 263 8.0E-13 T 13-09-2016 IPR014748 Crontonase, C-terminal THL1_RS15890 ade87464690c434a31ed275628e9f782 264 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 105 125 - T 13-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THL1_RS06500 9aaa21a24764da228f04c89c504d6978 363 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 7 196 2.3E-54 T 13-09-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS06500 9aaa21a24764da228f04c89c504d6978 363 SUPERFAMILY SSF142695 202 357 4.84E-38 T 13-09-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 THL1_RS06500 9aaa21a24764da228f04c89c504d6978 363 Gene3D G3DSA:3.90.870.10 3 206 3.3E-78 T 13-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain THL1_RS06500 9aaa21a24764da228f04c89c504d6978 363 PIRSF PIRSF001259 1 361 7.0E-96 T 13-09-2016 THL1_RS06500 9aaa21a24764da228f04c89c504d6978 363 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 195 2.1E-68 T 13-09-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS06500 9aaa21a24764da228f04c89c504d6978 363 PANTHER PTHR21327:SF6 1 356 1.1E-109 T 13-09-2016 THL1_RS06500 9aaa21a24764da228f04c89c504d6978 363 PANTHER PTHR21327 1 356 1.1E-109 T 13-09-2016 THL1_RS06500 9aaa21a24764da228f04c89c504d6978 363 Pfam PF00925 GTP cyclohydrolase II 205 356 2.1E-29 T 13-09-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 THL1_RS06500 9aaa21a24764da228f04c89c504d6978 363 SUPERFAMILY SSF55821 3 199 4.81E-68 T 13-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain THL1_RS03990 cd8e26403430c5da4bbb7bbc158c2478 121 SUPERFAMILY SSF53756 2 112 2.2E-16 T 13-09-2016 THL1_RS03990 cd8e26403430c5da4bbb7bbc158c2478 121 Gene3D G3DSA:3.40.50.2000 12 79 2.9E-8 T 13-09-2016 THL1_RS03990 cd8e26403430c5da4bbb7bbc158c2478 121 Pfam PF00534 Glycosyl transferases group 1 3 81 4.9E-12 T 13-09-2016 IPR001296 Glycosyl transferase, family 1 THL1_RS20405 287cbe753005c0fe822be89b4061a390 632 Pfam PF00563 EAL domain 378 612 6.2E-69 T 13-09-2016 IPR001633 EAL domain THL1_RS20405 287cbe753005c0fe822be89b4061a390 632 Gene3D G3DSA:3.20.20.450 376 623 4.0E-93 T 13-09-2016 IPR001633 EAL domain THL1_RS20405 287cbe753005c0fe822be89b4061a390 632 Gene3D G3DSA:3.30.70.270 204 368 2.5E-37 T 13-09-2016 THL1_RS20405 287cbe753005c0fe822be89b4061a390 632 Pfam PF00990 Diguanylate cyclase, GGDEF domain 203 358 2.0E-32 T 13-09-2016 IPR000160 GGDEF domain THL1_RS20405 287cbe753005c0fe822be89b4061a390 632 PANTHER PTHR33121:SF13 339 623 2.8E-81 T 13-09-2016 THL1_RS20405 287cbe753005c0fe822be89b4061a390 632 PANTHER PTHR33121 339 623 2.8E-81 T 13-09-2016 THL1_RS20405 287cbe753005c0fe822be89b4061a390 632 SUPERFAMILY SSF55073 208 362 5.89E-34 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS20405 287cbe753005c0fe822be89b4061a390 632 SMART SM00052 372 617 6.2E-105 T 13-09-2016 IPR001633 EAL domain THL1_RS20405 287cbe753005c0fe822be89b4061a390 632 SUPERFAMILY SSF55781 34 196 5.02E-16 T 13-09-2016 IPR029016 GAF domain-like THL1_RS20405 287cbe753005c0fe822be89b4061a390 632 SUPERFAMILY SSF141868 379 623 2.22E-86 T 13-09-2016 IPR001633 EAL domain THL1_RS20405 287cbe753005c0fe822be89b4061a390 632 Pfam PF13185 GAF domain 33 184 9.9E-12 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS20405 287cbe753005c0fe822be89b4061a390 632 SMART SM00267 192 363 9.6E-39 T 13-09-2016 IPR000160 GGDEF domain THL1_RS20405 287cbe753005c0fe822be89b4061a390 632 Gene3D G3DSA:3.30.450.40 10 198 1.0E-19 T 13-09-2016 IPR029016 GAF domain-like THL1_RS20405 287cbe753005c0fe822be89b4061a390 632 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 201 360 1.6E-26 T 13-09-2016 IPR000160 GGDEF domain THL1_RS14695 a4e25216f578aed2c0cd716ecf3ca191 513 SUPERFAMILY SSF48173 229 495 6.54E-56 T 13-09-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain THL1_RS14695 a4e25216f578aed2c0cd716ecf3ca191 513 Pfam PF04244 Deoxyribodipyrimidine photo-lyase-related protein 10 228 3.5E-78 T 13-09-2016 IPR007357 Deoxyribodipyrimidine photolyase-related protein THL1_RS14695 a4e25216f578aed2c0cd716ecf3ca191 513 Gene3D G3DSA:1.25.40.80 228 319 3.0E-10 T 13-09-2016 THL1_RS14695 a4e25216f578aed2c0cd716ecf3ca191 513 PANTHER PTHR38657 1 512 1.0E-201 T 13-09-2016 THL1_RS14695 a4e25216f578aed2c0cd716ecf3ca191 513 PANTHER PTHR38657:SF1 1 512 1.0E-201 T 13-09-2016 THL1_RS25145 a74ed5b05b5716550b6070437ed9dbd7 264 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 245 261 4.8E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS25145 a74ed5b05b5716550b6070437ed9dbd7 264 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 230 245 4.8E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS25145 a74ed5b05b5716550b6070437ed9dbd7 264 SUPERFAMILY SSF46689 215 260 1.16E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS25145 a74ed5b05b5716550b6070437ed9dbd7 264 SMART SM00342 179 261 5.0E-24 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS25145 a74ed5b05b5716550b6070437ed9dbd7 264 Gene3D G3DSA:1.10.10.60 158 215 7.6E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS25145 a74ed5b05b5716550b6070437ed9dbd7 264 SUPERFAMILY SSF51182 9 188 1.25E-15 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS25145 a74ed5b05b5716550b6070437ed9dbd7 264 Gene3D G3DSA:1.10.10.60 216 259 3.9E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS25145 a74ed5b05b5716550b6070437ed9dbd7 264 Gene3D G3DSA:2.60.120.10 20 94 2.5E-8 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS25145 a74ed5b05b5716550b6070437ed9dbd7 264 Pfam PF02311 AraC-like ligand binding domain 36 125 1.2E-6 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS25145 a74ed5b05b5716550b6070437ed9dbd7 264 PANTHER PTHR11019 8 259 9.8E-92 T 13-09-2016 THL1_RS25145 a74ed5b05b5716550b6070437ed9dbd7 264 PANTHER PTHR11019:SF98 8 259 9.8E-92 T 13-09-2016 THL1_RS25145 a74ed5b05b5716550b6070437ed9dbd7 264 Pfam PF12833 Helix-turn-helix domain 185 262 9.1E-25 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS19305 5a9b7f5f2ffa798c17af5b8d842545ab 484 PANTHER PTHR32024:SF3 3 483 2.2E-289 T 13-09-2016 THL1_RS19305 5a9b7f5f2ffa798c17af5b8d842545ab 484 PANTHER PTHR32024 3 483 2.2E-289 T 13-09-2016 THL1_RS19305 5a9b7f5f2ffa798c17af5b8d842545ab 484 PIRSF PIRSF006247 1 484 5.2E-170 T 13-09-2016 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 THL1_RS19305 5a9b7f5f2ffa798c17af5b8d842545ab 484 Pfam PF02386 Cation transport protein 49 476 3.7E-56 T 13-09-2016 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 THL1_RS24815 a82ebd761516772d75f4664ee0ebc58d 229 Gene3D G3DSA:3.40.30.10 53 209 6.6E-31 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS24815 a82ebd761516772d75f4664ee0ebc58d 229 Gene3D G3DSA:3.40.30.10 11 16 6.6E-31 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS24815 a82ebd761516772d75f4664ee0ebc58d 229 Pfam PF02630 SCO1/SenC 62 159 3.9E-14 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS24815 a82ebd761516772d75f4664ee0ebc58d 229 SUPERFAMILY SSF52833 58 209 1.17E-31 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS24815 a82ebd761516772d75f4664ee0ebc58d 229 PANTHER PTHR12151 3 167 5.4E-26 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 Gene3D G3DSA:3.30.470.20 202 446 1.8E-82 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 SUPERFAMILY SSF51230 1142 1215 1.44E-19 T 13-09-2016 IPR011053 Single hybrid motif THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 SUPERFAMILY SSF51246 332 448 1.2E-34 T 13-09-2016 IPR011054 Rudiment single hybrid motif THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 Gene3D G3DSA:2.40.50.100 1146 1215 7.1E-23 T 13-09-2016 THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 PANTHER PTHR18866 1112 1215 6.3E-268 T 13-09-2016 THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 PANTHER PTHR18866 1 546 6.3E-268 T 13-09-2016 THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 Gene3D G3DSA:3.30.1360.40 819 892 1.3E-23 T 13-09-2016 IPR024946 Arginine repressor C-terminal-like domain THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 SMART SM00878 338 446 1.1E-48 T 13-09-2016 IPR005482 Biotin carboxylase, C-terminal THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 109 2.0E-42 T 13-09-2016 IPR005481 Biotin carboxylase-like, N-terminal domain THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 Pfam PF00364 Biotin-requiring enzyme 1155 1213 4.3E-15 T 13-09-2016 IPR000089 Biotin/lipoyl attachment THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 SUPERFAMILY SSF50891 632 757 1.44E-31 T 13-09-2016 IPR029000 Cyclophilin-like domain THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 SUPERFAMILY SSF50891 933 1064 8.72E-25 T 13-09-2016 IPR029000 Cyclophilin-like domain THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 455 765 3.3E-85 T 13-09-2016 IPR003778 Carboxyltransferase domain, subdomain A and B THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 319 5.0E-60 T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 Gene3D G3DSA:3.30.1490.20 130 201 2.8E-23 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 SMART SM00796 816 1048 1.1E-112 T 13-09-2016 IPR003833 Carboxyltransferase domain, subdomain C and D THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 TIGRFAM TIGR02712 urea_carbox: urea carboxylase 2 1215 0.0 T 13-09-2016 IPR014084 Urea carboxylase KEGG: 00220+3.5.1.54+6.3.4.6|KEGG: 00791+3.5.1.54+6.3.4.6|MetaCyc: PWY-5169|MetaCyc: PWY-5703|UniPathway: UPA00258|UniPathway: UPA00258 THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 Pfam PF02626 Allophanate hydrolase subunit 2 478 750 2.9E-87 T 13-09-2016 IPR003778 Carboxyltransferase domain, subdomain A and B THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 Pfam PF02682 Allophanate hydrolase subunit 1 819 1037 1.0E-47 T 13-09-2016 IPR003833 Carboxyltransferase domain, subdomain C and D THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 SUPERFAMILY SSF160467 819 909 2.88E-17 T 13-09-2016 THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 Pfam PF02785 Biotin carboxylase C-terminal domain 338 446 1.5E-31 T 13-09-2016 IPR005482 Biotin carboxylase, C-terminal THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 SUPERFAMILY SSF52440 1 112 5.25E-44 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 SMART SM00797 477 767 3.8E-165 T 13-09-2016 IPR003778 Carboxyltransferase domain, subdomain A and B THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 SUPERFAMILY SSF56059 83 354 2.65E-65 T 13-09-2016 THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 Gene3D G3DSA:3.40.50.20 1 129 4.4E-45 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 Gene3D G3DSA:2.40.100.10 632 764 6.7E-32 T 13-09-2016 IPR029000 Cyclophilin-like domain THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 Gene3D G3DSA:2.40.100.10 933 1071 4.4E-44 T 13-09-2016 IPR029000 Cyclophilin-like domain THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 PANTHER PTHR18866:SF91 1112 1215 6.3E-268 T 13-09-2016 THL1_RS21525 87b4b97ac80827d94e062e96a3edb7d6 1217 PANTHER PTHR18866:SF91 1 546 6.3E-268 T 13-09-2016 THL1_RS07600 ab7a3167fee3eec7e3f43d1f24965b70 281 PANTHER PTHR32243 4 281 1.4E-137 T 13-09-2016 THL1_RS07600 ab7a3167fee3eec7e3f43d1f24965b70 281 SUPERFAMILY SSF161098 13 281 8.5E-62 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07600 ab7a3167fee3eec7e3f43d1f24965b70 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 273 2.2E-14 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07600 ab7a3167fee3eec7e3f43d1f24965b70 281 Gene3D G3DSA:1.10.3720.10 12 266 1.3E-52 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07600 ab7a3167fee3eec7e3f43d1f24965b70 281 PANTHER PTHR32243:SF23 4 281 1.4E-137 T 13-09-2016 THL1_RS06060 25d1019cb51a0bc6730a37402e8b6e62 418 PANTHER PTHR30629 1 398 3.1E-83 T 13-09-2016 THL1_RS06060 25d1019cb51a0bc6730a37402e8b6e62 418 SUPERFAMILY SSF56349 99 385 6.47E-58 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS06060 25d1019cb51a0bc6730a37402e8b6e62 418 Gene3D G3DSA:1.10.443.10 202 382 6.6E-28 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS06060 25d1019cb51a0bc6730a37402e8b6e62 418 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 99 146 3.3E-6 T 13-09-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THL1_RS06060 25d1019cb51a0bc6730a37402e8b6e62 418 PANTHER PTHR30629:SF2 1 398 3.1E-83 T 13-09-2016 THL1_RS06060 25d1019cb51a0bc6730a37402e8b6e62 418 Gene3D G3DSA:1.10.150.130 99 192 3.3E-16 T 13-09-2016 IPR023109 Integrase/recombinase, N-terminal THL1_RS06060 25d1019cb51a0bc6730a37402e8b6e62 418 Pfam PF00589 Phage integrase family 204 375 1.3E-20 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS06060 25d1019cb51a0bc6730a37402e8b6e62 418 Pfam PF13356 Domain of unknown function (DUF4102) 2 88 4.6E-17 T 13-09-2016 IPR025166 Domain of unknown function DUF4102 THL1_RS08990 af27df0419b0fb00103472f63fb642e7 175 Gene3D G3DSA:3.90.1720.10 39 166 5.4E-44 T 13-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS08990 af27df0419b0fb00103472f63fb642e7 175 PANTHER PTHR21666 9 166 1.3E-39 T 13-09-2016 THL1_RS08990 af27df0419b0fb00103472f63fb642e7 175 SUPERFAMILY SSF54001 37 166 5.56E-41 T 13-09-2016 THL1_RS08990 af27df0419b0fb00103472f63fb642e7 175 Pfam PF00877 NlpC/P60 family 55 163 2.0E-29 T 13-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS15390 328d906a10ebfe471996f3563aa33b86 179 Pfam PF07291 Methylamine utilisation protein MauE 4 166 6.5E-35 T 13-09-2016 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 UniPathway: UPA00895 THL1_RS07965 9fca90cda607f6d14eb31be2c3bd4aa3 256 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 242 6.2E-10 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS07965 9fca90cda607f6d14eb31be2c3bd4aa3 256 Gene3D G3DSA:3.40.190.10 34 135 1.4E-7 T 13-09-2016 THL1_RS07965 9fca90cda607f6d14eb31be2c3bd4aa3 256 SUPERFAMILY SSF53850 30 245 3.14E-25 T 13-09-2016 THL1_RS10515 c7ea8639eae4af22b497414b0b79eb4e 73 SUPERFAMILY SSF50182 22 72 3.05E-16 T 13-09-2016 IPR010920 LSM domain THL1_RS10515 c7ea8639eae4af22b497414b0b79eb4e 73 Pfam PF06004 Bacterial protein of unknown function (DUF903) 25 72 6.2E-21 T 13-09-2016 IPR010305 Protein of unknown function DUF903 THL1_RS10515 c7ea8639eae4af22b497414b0b79eb4e 73 PANTHER PTHR37011 2 73 4.7E-33 T 13-09-2016 THL1_RS10515 c7ea8639eae4af22b497414b0b79eb4e 73 PANTHER PTHR37011:SF1 2 73 4.7E-33 T 13-09-2016 THL1_RS10515 c7ea8639eae4af22b497414b0b79eb4e 73 Gene3D G3DSA:2.30.30.100 21 73 5.3E-22 T 13-09-2016 THL1_RS21850 f1de482488a23c1880bcf61822a92179 423 SUPERFAMILY SSF103473 15 417 2.35E-39 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS21850 f1de482488a23c1880bcf61822a92179 423 Pfam PF11700 Vacuole effluxer Atg22 like 58 420 1.1E-39 T 13-09-2016 IPR024671 Autophagy-related protein 22-like THL1_RS21850 f1de482488a23c1880bcf61822a92179 423 PANTHER PTHR23519 1 420 8.1E-63 T 13-09-2016 THL1_RS21850 f1de482488a23c1880bcf61822a92179 423 Gene3D G3DSA:1.20.1250.20 42 208 2.3E-9 T 13-09-2016 THL1_RS21850 f1de482488a23c1880bcf61822a92179 423 Gene3D G3DSA:1.20.1250.20 234 415 6.4E-24 T 13-09-2016 THL1_RS00700 463d306682c9c2f4d4a98ed40d073c3c 272 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 8 270 1.3E-125 T 13-09-2016 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 THL1_RS00700 463d306682c9c2f4d4a98ed40d073c3c 272 Gene3D G3DSA:1.10.3720.10 19 269 2.8E-50 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00700 463d306682c9c2f4d4a98ed40d073c3c 272 PANTHER PTHR30406:SF6 1 270 3.6E-156 T 13-09-2016 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 THL1_RS00700 463d306682c9c2f4d4a98ed40d073c3c 272 SUPERFAMILY SSF161098 15 267 9.25E-55 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00700 463d306682c9c2f4d4a98ed40d073c3c 272 PANTHER PTHR30406 1 270 3.6E-156 T 13-09-2016 THL1_RS00700 463d306682c9c2f4d4a98ed40d073c3c 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 269 3.7E-24 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00700 463d306682c9c2f4d4a98ed40d073c3c 272 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 10 268 7.4E-91 T 13-09-2016 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 THL1_RS26070 2f8c640df2b1140bd23e0b015e1ec209 96 Gene3D G3DSA:2.160.10.10 21 88 3.1E-5 T 13-09-2016 THL1_RS26070 2f8c640df2b1140bd23e0b015e1ec209 96 SUPERFAMILY SSF51161 21 87 9.42E-5 T 13-09-2016 IPR011004 Trimeric LpxA-like THL1_RS13660 01131a150e4ab437ab9874dd85185705 465 SMART SM01150 13 412 6.1E-241 T 13-09-2016 IPR009770 Domain of unknown function DUF1338 THL1_RS13660 01131a150e4ab437ab9874dd85185705 465 Pfam PF07063 Domain of unknown function (DUF1338) 11 412 3.1E-120 T 13-09-2016 IPR009770 Domain of unknown function DUF1338 THL1_RS13660 01131a150e4ab437ab9874dd85185705 465 PANTHER PTHR39479 1 461 6.2E-259 T 13-09-2016 THL1_RS13660 01131a150e4ab437ab9874dd85185705 465 PANTHER PTHR39479:SF2 1 461 6.2E-259 T 13-09-2016 THL1_RS14390 d6508a3467625181ecea4c9efed1b675 452 TIGRFAM TIGR03229 benzo_1_2_benA: benzoate 1,2-dioxygenase, large subunit 8 438 2.4E-270 T 13-09-2016 IPR017639 Benzoate 1,2-dioxygenase, large subunit THL1_RS14390 d6508a3467625181ecea4c9efed1b675 452 SUPERFAMILY SSF55961 164 446 3.92E-66 T 13-09-2016 THL1_RS14390 d6508a3467625181ecea4c9efed1b675 452 SUPERFAMILY SSF50022 13 163 8.38E-45 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS14390 d6508a3467625181ecea4c9efed1b675 452 Pfam PF00355 Rieske [2Fe-2S] domain 45 129 8.9E-22 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS14390 d6508a3467625181ecea4c9efed1b675 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 30 55 1.8E-46 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS14390 d6508a3467625181ecea4c9efed1b675 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 81 101 1.8E-46 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS14390 d6508a3467625181ecea4c9efed1b675 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 148 174 1.8E-46 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS14390 d6508a3467625181ecea4c9efed1b675 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 60 75 1.8E-46 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS14390 d6508a3467625181ecea4c9efed1b675 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 102 122 1.8E-46 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS14390 d6508a3467625181ecea4c9efed1b675 452 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 189 211 1.8E-46 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS14390 d6508a3467625181ecea4c9efed1b675 452 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 88 111 - T 13-09-2016 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 THL1_RS14390 d6508a3467625181ecea4c9efed1b675 452 Gene3D G3DSA:2.102.10.10 45 153 2.1E-23 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS14390 d6508a3467625181ecea4c9efed1b675 452 PANTHER PTHR21266:SF30 1 383 5.1E-152 T 13-09-2016 THL1_RS14390 d6508a3467625181ecea4c9efed1b675 452 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 196 382 7.5E-16 T 13-09-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 THL1_RS14390 d6508a3467625181ecea4c9efed1b675 452 PANTHER PTHR21266 1 383 5.1E-152 T 13-09-2016 THL1_RS14390 d6508a3467625181ecea4c9efed1b675 452 Gene3D G3DSA:3.90.380.10 154 444 4.4E-89 T 13-09-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 THL1_RS23045 0136c36b7adca8e0dacec9ccf586693c 434 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 127 1.8E-25 T 13-09-2016 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 THL1_RS23045 0136c36b7adca8e0dacec9ccf586693c 434 SUPERFAMILY SSF55021 350 421 9.89E-16 T 13-09-2016 THL1_RS23045 0136c36b7adca8e0dacec9ccf586693c 434 PANTHER PTHR21499 4 367 5.4E-137 T 13-09-2016 THL1_RS23045 0136c36b7adca8e0dacec9ccf586693c 434 SUPERFAMILY SSF55347 135 300 2.09E-53 T 13-09-2016 THL1_RS23045 0136c36b7adca8e0dacec9ccf586693c 434 Pfam PF01842 ACT domain 352 419 5.1E-16 T 13-09-2016 IPR002912 ACT domain GO:0008152|GO:0016597 THL1_RS23045 0136c36b7adca8e0dacec9ccf586693c 434 PIRSF PIRSF000098 1 433 3.4E-168 T 13-09-2016 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 THL1_RS23045 0136c36b7adca8e0dacec9ccf586693c 434 SUPERFAMILY SSF51735 2 156 1.55E-35 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23045 0136c36b7adca8e0dacec9ccf586693c 434 PANTHER PTHR21499:SF2 4 367 5.4E-137 T 13-09-2016 THL1_RS23045 0136c36b7adca8e0dacec9ccf586693c 434 Pfam PF00742 Homoserine dehydrogenase 135 313 1.9E-64 T 13-09-2016 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 THL1_RS23045 0136c36b7adca8e0dacec9ccf586693c 434 Gene3D G3DSA:3.30.360.10 147 296 1.6E-57 T 13-09-2016 THL1_RS23045 0136c36b7adca8e0dacec9ccf586693c 434 Gene3D G3DSA:3.30.70.260 352 422 4.2E-14 T 13-09-2016 THL1_RS23045 0136c36b7adca8e0dacec9ccf586693c 434 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 181 203 - T 13-09-2016 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 THL1_RS23045 0136c36b7adca8e0dacec9ccf586693c 434 Gene3D G3DSA:3.40.50.720 2 146 5.5E-50 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 PANTHER PTHR13847 113 213 1.0E-42 T 13-09-2016 THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 PANTHER PTHR13847 586 873 1.0E-42 T 13-09-2016 THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 Gene3D G3DSA:3.50.50.60 302 467 2.4E-27 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 Gene3D G3DSA:3.50.50.60 164 226 2.4E-27 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 SUPERFAMILY SSF101790 877 963 1.32E-16 T 13-09-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 Gene3D G3DSA:3.30.70.1400 644 725 8.5E-20 T 13-09-2016 THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 Gene3D G3DSA:3.30.1360.120 736 830 1.1E-29 T 13-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 Gene3D G3DSA:3.30.1360.120 585 643 1.1E-29 T 13-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 165 187 1.5E-9 T 13-09-2016 THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 642 657 1.5E-9 T 13-09-2016 THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 165 416 9.8E-17 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 SUPERFAMILY SSF103025 584 867 3.14E-83 T 13-09-2016 THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 861 952 1.1E-11 T 13-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 16 96 6.1E-22 T 13-09-2016 THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 Pfam PF01571 Aminomethyltransferase folate-binding domain 590 853 4.2E-74 T 13-09-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 SUPERFAMILY SSF51905 164 422 1.21E-33 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 PANTHER PTHR13847:SF189 113 213 1.0E-42 T 13-09-2016 THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 PANTHER PTHR13847:SF189 586 873 1.0E-42 T 13-09-2016 THL1_RS07325 404e9a9c786bdf508100bfe27d218c94 965 Gene3D G3DSA:2.40.30.110 876 951 2.9E-13 T 13-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS18100 eae0ca853a06e57fa05208b8962bd3b2 147 Gene3D G3DSA:3.10.129.10 10 140 5.0E-21 T 13-09-2016 IPR029069 HotDog domain THL1_RS18100 eae0ca853a06e57fa05208b8962bd3b2 147 SUPERFAMILY SSF54637 11 141 3.87E-23 T 13-09-2016 IPR029069 HotDog domain THL1_RS18100 eae0ca853a06e57fa05208b8962bd3b2 147 Pfam PF13279 Thioesterase-like superfamily 21 137 1.6E-12 T 13-09-2016 THL1_RS18100 eae0ca853a06e57fa05208b8962bd3b2 147 PANTHER PTHR31793 13 140 8.9E-25 T 13-09-2016 THL1_RS22555 7534eaa4d0cc3e0d57d06b99ebb9d65b 438 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 22 200 8.0E-49 T 13-09-2016 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THL1_RS22555 7534eaa4d0cc3e0d57d06b99ebb9d65b 438 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 4 326 22.925 T 13-09-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THL1_RS22555 7534eaa4d0cc3e0d57d06b99ebb9d65b 438 Pfam PF01171 PP-loop family 21 197 1.5E-52 T 13-09-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal THL1_RS22555 7534eaa4d0cc3e0d57d06b99ebb9d65b 438 PANTHER PTHR11807:SF2 22 412 4.6E-73 T 13-09-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THL1_RS22555 7534eaa4d0cc3e0d57d06b99ebb9d65b 438 SUPERFAMILY SSF82829 250 322 3.66E-17 T 13-09-2016 THL1_RS22555 7534eaa4d0cc3e0d57d06b99ebb9d65b 438 SUPERFAMILY SSF56037 330 429 2.88E-16 T 13-09-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 THL1_RS22555 7534eaa4d0cc3e0d57d06b99ebb9d65b 438 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 359 401 6.2E-11 T 13-09-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THL1_RS22555 7534eaa4d0cc3e0d57d06b99ebb9d65b 438 PANTHER PTHR11807 22 412 4.6E-73 T 13-09-2016 THL1_RS22555 7534eaa4d0cc3e0d57d06b99ebb9d65b 438 SMART SM00977 359 427 1.1E-13 T 13-09-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THL1_RS22555 7534eaa4d0cc3e0d57d06b99ebb9d65b 438 Pfam PF11734 TilS substrate C-terminal domain 359 427 7.4E-13 T 13-09-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THL1_RS22555 7534eaa4d0cc3e0d57d06b99ebb9d65b 438 Pfam PF09179 TilS substrate binding domain 252 317 9.7E-14 T 13-09-2016 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THL1_RS22555 7534eaa4d0cc3e0d57d06b99ebb9d65b 438 SUPERFAMILY SSF52402 19 230 7.94E-58 T 13-09-2016 THL1_RS22555 7534eaa4d0cc3e0d57d06b99ebb9d65b 438 Gene3D G3DSA:3.40.50.620 22 177 2.8E-11 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS27840 5a37b9cd78270fbbbeb5ac53e2b0d2a1 301 TIGRFAM TIGR00761 argB: acetylglutamate kinase 29 272 9.0E-80 T 13-09-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS27840 5a37b9cd78270fbbbeb5ac53e2b0d2a1 301 PANTHER PTHR23342 1 297 2.4E-124 T 13-09-2016 THL1_RS27840 5a37b9cd78270fbbbeb5ac53e2b0d2a1 301 Gene3D G3DSA:3.40.1160.10 27 296 1.1E-105 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS27840 5a37b9cd78270fbbbeb5ac53e2b0d2a1 301 Hamap MF_00082_B Acetylglutamate kinase [argB]. 26 297 37.711 T 13-09-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS27840 5a37b9cd78270fbbbeb5ac53e2b0d2a1 301 Pfam PF00696 Amino acid kinase family 28 274 2.0E-44 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS27840 5a37b9cd78270fbbbeb5ac53e2b0d2a1 301 PIRSF PIRSF000728 13 297 3.2E-112 T 13-09-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS27840 5a37b9cd78270fbbbeb5ac53e2b0d2a1 301 PRINTS PR00474 Glutamate 5-kinase family signature 247 267 4.0E-8 T 13-09-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 THL1_RS27840 5a37b9cd78270fbbbeb5ac53e2b0d2a1 301 PRINTS PR00474 Glutamate 5-kinase family signature 59 73 4.0E-8 T 13-09-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 THL1_RS27840 5a37b9cd78270fbbbeb5ac53e2b0d2a1 301 PRINTS PR00474 Glutamate 5-kinase family signature 197 224 4.0E-8 T 13-09-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 THL1_RS27840 5a37b9cd78270fbbbeb5ac53e2b0d2a1 301 SUPERFAMILY SSF53633 10 298 2.49E-99 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS27365 91e171d37fe09c7bb6891680698f4ada 629 PANTHER PTHR31632 362 597 4.7E-41 T 13-09-2016 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 THL1_RS27365 91e171d37fe09c7bb6891680698f4ada 629 SUPERFAMILY SSF46626 111 221 3.39E-20 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS27365 91e171d37fe09c7bb6891680698f4ada 629 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 132 215 1.4E-12 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS27365 91e171d37fe09c7bb6891680698f4ada 629 PANTHER PTHR31632:SF4 362 597 4.7E-41 T 13-09-2016 THL1_RS27365 91e171d37fe09c7bb6891680698f4ada 629 Gene3D G3DSA:1.10.760.10 122 222 3.7E-18 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS27365 91e171d37fe09c7bb6891680698f4ada 629 Pfam PF03239 Iron permease FTR1 family 343 474 4.8E-14 T 13-09-2016 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 THL1_RS09970 f514ba5ef769669b30ab3b912ca53cb9 179 Gene3D G3DSA:1.10.357.10 59 178 1.6E-31 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS09970 f514ba5ef769669b30ab3b912ca53cb9 179 SUPERFAMILY SSF48498 78 177 7.41E-19 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS09970 f514ba5ef769669b30ab3b912ca53cb9 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 5.6E-10 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS09970 f514ba5ef769669b30ab3b912ca53cb9 179 Gene3D G3DSA:1.10.10.60 41 58 3.5E-5 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS09970 f514ba5ef769669b30ab3b912ca53cb9 179 PANTHER PTHR30328 7 179 7.1E-66 T 13-09-2016 THL1_RS09970 f514ba5ef769669b30ab3b912ca53cb9 179 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.5E-5 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS09970 f514ba5ef769669b30ab3b912ca53cb9 179 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.5E-5 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS09970 f514ba5ef769669b30ab3b912ca53cb9 179 PANTHER PTHR30328:SF22 7 179 7.1E-66 T 13-09-2016 THL1_RS09970 f514ba5ef769669b30ab3b912ca53cb9 179 SUPERFAMILY SSF46689 1 69 2.26E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS09970 f514ba5ef769669b30ab3b912ca53cb9 179 Gene3D G3DSA:1.10.10.60 1 40 6.5E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS08015 38cd55fab9e2ca23fefc3b41dce4b00d 230 SUPERFAMILY SSF55174 1 87 3.53E-10 T 13-09-2016 THL1_RS08015 38cd55fab9e2ca23fefc3b41dce4b00d 230 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 224 1.2E-36 T 13-09-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 THL1_RS08015 38cd55fab9e2ca23fefc3b41dce4b00d 230 Pfam PF00849 RNA pseudouridylate synthase 62 190 8.0E-11 T 13-09-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS08015 38cd55fab9e2ca23fefc3b41dce4b00d 230 Gene3D G3DSA:3.10.290.10 1 63 1.0E-12 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS08015 38cd55fab9e2ca23fefc3b41dce4b00d 230 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 13-09-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 THL1_RS08015 38cd55fab9e2ca23fefc3b41dce4b00d 230 PANTHER PTHR21600 1 228 2.8E-62 T 13-09-2016 THL1_RS08015 38cd55fab9e2ca23fefc3b41dce4b00d 230 PANTHER PTHR21600:SF19 1 228 2.8E-62 T 13-09-2016 THL1_RS08015 38cd55fab9e2ca23fefc3b41dce4b00d 230 SUPERFAMILY SSF55120 61 227 4.0E-39 T 13-09-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS08015 38cd55fab9e2ca23fefc3b41dce4b00d 230 SMART SM00363 1 58 8.0E-5 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS20360 b9d071952c886b0a271e67c3cecade3d 219 SUPERFAMILY SSF52833 41 197 3.27E-27 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS20360 b9d071952c886b0a271e67c3cecade3d 219 Gene3D G3DSA:3.40.30.10 13 170 1.1E-29 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS20360 b9d071952c886b0a271e67c3cecade3d 219 Pfam PF02630 SCO1/SenC 44 146 8.1E-12 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS20360 b9d071952c886b0a271e67c3cecade3d 219 PANTHER PTHR12151 48 162 3.7E-25 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS04600 5b47e433a78568ebb76ce59f25ee142f 144 SUPERFAMILY SSF52833 17 93 3.45E-7 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS04600 5b47e433a78568ebb76ce59f25ee142f 144 Pfam PF04214 Protein of unknown function, DUF 48 115 2.7E-28 T 13-09-2016 IPR007332 Protein of unknown function DUF411 THL1_RS11780 7b5d9c43de606c85ed5345c650e15c62 320 PANTHER PTHR30582:SF1 33 311 1.9E-92 T 13-09-2016 THL1_RS11780 7b5d9c43de606c85ed5345c650e15c62 320 Gene3D G3DSA:2.40.440.10 92 233 7.6E-33 T 13-09-2016 THL1_RS11780 7b5d9c43de606c85ed5345c650e15c62 320 Pfam PF03734 L,D-transpeptidase catalytic domain 99 232 2.2E-16 T 13-09-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 THL1_RS11780 7b5d9c43de606c85ed5345c650e15c62 320 PANTHER PTHR30582 33 311 1.9E-92 T 13-09-2016 THL1_RS11780 7b5d9c43de606c85ed5345c650e15c62 320 SUPERFAMILY SSF141523 97 232 3.92E-29 T 13-09-2016 THL1_RS10980 2ed704acc87a57b58b76748f6cc70581 405 Gene3D G3DSA:3.40.47.10 261 404 5.6E-47 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS10980 2ed704acc87a57b58b76748f6cc70581 405 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 152 168 - T 13-09-2016 IPR018201 Beta-ketoacyl synthase, active site THL1_RS10980 2ed704acc87a57b58b76748f6cc70581 405 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 244 1.8E-47 T 13-09-2016 IPR014030 Beta-ketoacyl synthase, N-terminal THL1_RS10980 2ed704acc87a57b58b76748f6cc70581 405 Gene3D G3DSA:3.40.47.10 6 257 2.0E-60 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS10980 2ed704acc87a57b58b76748f6cc70581 405 SMART SM00825 Beta-ketoacyl synthase 4 405 1.6E-13 T 13-09-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain THL1_RS10980 2ed704acc87a57b58b76748f6cc70581 405 SUPERFAMILY SSF53901 1 251 3.64E-63 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS10980 2ed704acc87a57b58b76748f6cc70581 405 PANTHER PTHR11712 1 403 6.2E-164 T 13-09-2016 THL1_RS10980 2ed704acc87a57b58b76748f6cc70581 405 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 359 2.6E-28 T 13-09-2016 IPR014031 Beta-ketoacyl synthase, C-terminal THL1_RS10980 2ed704acc87a57b58b76748f6cc70581 405 SUPERFAMILY SSF53901 213 403 2.43E-59 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS06905 e351975fa7de3ee1b844c5d5e562f070 655 PANTHER PTHR13847 216 573 1.1E-92 T 13-09-2016 THL1_RS06905 e351975fa7de3ee1b844c5d5e562f070 655 PANTHER PTHR13847 593 653 1.1E-92 T 13-09-2016 THL1_RS06905 e351975fa7de3ee1b844c5d5e562f070 655 SUPERFAMILY SSF54373 466 534 5.1E-5 T 13-09-2016 THL1_RS06905 e351975fa7de3ee1b844c5d5e562f070 655 Gene3D G3DSA:3.40.50.150 8 239 7.5E-92 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS06905 e351975fa7de3ee1b844c5d5e562f070 655 PANTHER PTHR13847:SF206 216 573 1.1E-92 T 13-09-2016 THL1_RS06905 e351975fa7de3ee1b844c5d5e562f070 655 PANTHER PTHR13847:SF206 593 653 1.1E-92 T 13-09-2016 THL1_RS06905 e351975fa7de3ee1b844c5d5e562f070 655 Pfam PF01266 FAD dependent oxidoreductase 259 623 1.8E-44 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS06905 e351975fa7de3ee1b844c5d5e562f070 655 SUPERFAMILY SSF51905 258 465 5.31E-35 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS06905 e351975fa7de3ee1b844c5d5e562f070 655 SUPERFAMILY SSF51905 559 652 5.31E-35 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS06905 e351975fa7de3ee1b844c5d5e562f070 655 Gene3D G3DSA:3.50.50.60 255 327 4.7E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS06905 e351975fa7de3ee1b844c5d5e562f070 655 Gene3D G3DSA:3.50.50.60 559 649 4.7E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS06905 e351975fa7de3ee1b844c5d5e562f070 655 Gene3D G3DSA:3.50.50.60 384 464 4.7E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS06905 e351975fa7de3ee1b844c5d5e562f070 655 SUPERFAMILY SSF53335 14 110 1.06E-6 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS06905 e351975fa7de3ee1b844c5d5e562f070 655 SUPERFAMILY SSF53335 138 213 1.06E-6 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS06905 e351975fa7de3ee1b844c5d5e562f070 655 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 113 232 5.9E-42 T 13-09-2016 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 THL1_RS06905 e351975fa7de3ee1b844c5d5e562f070 655 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 5 647 27.005 T 13-09-2016 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 THL1_RS06905 e351975fa7de3ee1b844c5d5e562f070 655 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 258 652 2.6E-136 T 13-09-2016 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 THL1_RS06325 20431a220cdb32982881aac7beb4de01 259 PANTHER PTHR30283 2 255 1.7E-124 T 13-09-2016 THL1_RS06325 20431a220cdb32982881aac7beb4de01 259 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 255 38.306 T 13-09-2016 IPR005583 Peroxide stress protein YaaA THL1_RS06325 20431a220cdb32982881aac7beb4de01 259 PANTHER PTHR30283:SF3 2 255 1.7E-124 T 13-09-2016 THL1_RS06325 20431a220cdb32982881aac7beb4de01 259 Pfam PF03883 Protein of unknown function (DUF328) 1 242 1.9E-91 T 13-09-2016 IPR005583 Peroxide stress protein YaaA THL1_RS24705 b024016d74a851f6060de039563d59eb 469 Gene3D G3DSA:1.10.8.60 325 392 6.4E-23 T 13-09-2016 THL1_RS24705 b024016d74a851f6060de039563d59eb 469 PANTHER PTHR32071 1 468 4.4E-167 T 13-09-2016 THL1_RS24705 b024016d74a851f6060de039563d59eb 469 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 237 252 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS24705 b024016d74a851f6060de039563d59eb 469 Gene3D G3DSA:3.40.50.300 142 322 1.2E-47 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24705 b024016d74a851f6060de039563d59eb 469 Pfam PF00072 Response regulator receiver domain 5 112 4.1E-26 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS24705 b024016d74a851f6060de039563d59eb 469 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 175 188 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS24705 b024016d74a851f6060de039563d59eb 469 SUPERFAMILY SSF52540 143 392 2.13E-63 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24705 b024016d74a851f6060de039563d59eb 469 Gene3D G3DSA:1.10.10.60 421 462 4.1E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS24705 b024016d74a851f6060de039563d59eb 469 Pfam PF02954 Bacterial regulatory protein, Fis family 422 460 3.0E-10 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS24705 b024016d74a851f6060de039563d59eb 469 Gene3D G3DSA:3.40.50.2300 3 129 2.4E-34 T 13-09-2016 THL1_RS24705 b024016d74a851f6060de039563d59eb 469 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 364 373 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS24705 b024016d74a851f6060de039563d59eb 469 SMART SM00448 3 114 6.2E-32 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS24705 b024016d74a851f6060de039563d59eb 469 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 443 463 3.9E-9 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS24705 b024016d74a851f6060de039563d59eb 469 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 426 443 3.9E-9 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS24705 b024016d74a851f6060de039563d59eb 469 SMART SM00382 171 313 2.7E-4 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS24705 b024016d74a851f6060de039563d59eb 469 SUPERFAMILY SSF46689 364 462 2.82E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS24705 b024016d74a851f6060de039563d59eb 469 Pfam PF00158 Sigma-54 interaction domain 150 317 1.0E-62 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS24705 b024016d74a851f6060de039563d59eb 469 SUPERFAMILY SSF52172 4 193 1.34E-41 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS00760 14407b3424aabf802e9933953f46ac12 305 SUPERFAMILY SSF53850 97 294 3.94E-31 T 13-09-2016 THL1_RS00760 14407b3424aabf802e9933953f46ac12 305 Pfam PF03466 LysR substrate binding domain 96 297 8.8E-37 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS00760 14407b3424aabf802e9933953f46ac12 305 PANTHER PTHR30346:SF0 5 297 6.7E-81 T 13-09-2016 THL1_RS00760 14407b3424aabf802e9933953f46ac12 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 63 1.1E-12 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS00760 14407b3424aabf802e9933953f46ac12 305 Gene3D G3DSA:3.40.190.10 98 183 1.2E-11 T 13-09-2016 THL1_RS00760 14407b3424aabf802e9933953f46ac12 305 PANTHER PTHR30346 5 297 6.7E-81 T 13-09-2016 THL1_RS00760 14407b3424aabf802e9933953f46ac12 305 SUPERFAMILY SSF46785 7 86 6.6E-12 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00760 14407b3424aabf802e9933953f46ac12 305 Gene3D G3DSA:3.40.190.10 184 268 2.5E-26 T 13-09-2016 THL1_RS00760 14407b3424aabf802e9933953f46ac12 305 Gene3D G3DSA:1.10.10.10 7 91 8.9E-16 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12950 8eeaad10d7e919154f7ac8c643df777c 238 SUPERFAMILY SSF52218 4 226 5.79E-69 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS12950 8eeaad10d7e919154f7ac8c643df777c 238 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 6 224 4.5E-127 T 13-09-2016 IPR014063 Arsenate resistance ArsH THL1_RS12950 8eeaad10d7e919154f7ac8c643df777c 238 Pfam PF03358 NADPH-dependent FMN reductase 32 174 5.4E-28 T 13-09-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 THL1_RS12950 8eeaad10d7e919154f7ac8c643df777c 238 PANTHER PTHR30041 13 238 6.7E-138 T 13-09-2016 THL1_RS12950 8eeaad10d7e919154f7ac8c643df777c 238 Gene3D G3DSA:3.40.50.360 4 228 3.9E-106 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS12950 8eeaad10d7e919154f7ac8c643df777c 238 PANTHER PTHR30041:SF1 13 238 6.7E-138 T 13-09-2016 THL1_RS24830 169a1e47f7a1df08dbaf64d77d876291 204 SUPERFAMILY SSF53955 67 198 5.94E-46 T 13-09-2016 IPR023346 Lysozyme-like domain THL1_RS24830 169a1e47f7a1df08dbaf64d77d876291 204 Gene3D G3DSA:1.10.530.10 70 198 7.9E-46 T 13-09-2016 THL1_RS24830 169a1e47f7a1df08dbaf64d77d876291 204 Pfam PF01464 Transglycosylase SLT domain 79 171 6.3E-28 T 13-09-2016 IPR008258 Transglycosylase SLT domain 1 THL1_RS24830 169a1e47f7a1df08dbaf64d77d876291 204 PANTHER PTHR21666 56 195 3.1E-38 T 13-09-2016 THL1_RS05390 08bb76a0af535a360d65210de5dd19ba 324 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 45 314 3.0E-111 T 13-09-2016 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 THL1_RS05390 08bb76a0af535a360d65210de5dd19ba 324 PANTHER PTHR38418:SF1 5 324 2.1E-38 T 13-09-2016 THL1_RS05390 08bb76a0af535a360d65210de5dd19ba 324 Gene3D G3DSA:3.10.580.10 196 320 1.6E-39 T 13-09-2016 THL1_RS05390 08bb76a0af535a360d65210de5dd19ba 324 SUPERFAMILY SSF53697 7 321 2.22E-70 T 13-09-2016 THL1_RS05390 08bb76a0af535a360d65210de5dd19ba 324 PIRSF PIRSF004692 1 324 2.2E-134 T 13-09-2016 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 THL1_RS05390 08bb76a0af535a360d65210de5dd19ba 324 PANTHER PTHR38418 5 324 2.1E-38 T 13-09-2016 THL1_RS05390 08bb76a0af535a360d65210de5dd19ba 324 Pfam PF00571 CBS domain 211 258 6.2E-7 T 13-09-2016 IPR000644 CBS domain THL1_RS05390 08bb76a0af535a360d65210de5dd19ba 324 Pfam PF00571 CBS domain 270 321 5.1E-7 T 13-09-2016 IPR000644 CBS domain THL1_RS05390 08bb76a0af535a360d65210de5dd19ba 324 Gene3D G3DSA:3.40.50.10490 10 195 5.3E-51 T 13-09-2016 THL1_RS05390 08bb76a0af535a360d65210de5dd19ba 324 Pfam PF01380 SIS domain 41 172 2.3E-32 T 13-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 THL1_RS05390 08bb76a0af535a360d65210de5dd19ba 324 SMART SM00116 210 258 7.2E-4 T 13-09-2016 IPR000644 CBS domain THL1_RS05390 08bb76a0af535a360d65210de5dd19ba 324 SMART SM00116 275 323 0.92 T 13-09-2016 IPR000644 CBS domain THL1_RS20255 76e7ed70ce7d015ba1be607381e06454 662 PANTHER PTHR30509:SF1 6 249 5.2E-138 T 13-09-2016 THL1_RS20255 76e7ed70ce7d015ba1be607381e06454 662 PANTHER PTHR30509 6 249 5.2E-138 T 13-09-2016 THL1_RS20255 76e7ed70ce7d015ba1be607381e06454 662 PANTHER PTHR30509 302 634 5.2E-138 T 13-09-2016 THL1_RS20255 76e7ed70ce7d015ba1be607381e06454 662 Pfam PF04632 Fusaric acid resistance protein family 16 654 6.3E-192 T 13-09-2016 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 THL1_RS20255 76e7ed70ce7d015ba1be607381e06454 662 PANTHER PTHR30509:SF1 302 634 5.2E-138 T 13-09-2016 THL1_RS09415 3db08741e71e7ced30a4a7a8b90a0bab 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 283 2.3E-35 T 13-09-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 THL1_RS09415 3db08741e71e7ced30a4a7a8b90a0bab 296 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 3 291 4.6E-115 T 13-09-2016 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 THL1_RS09415 3db08741e71e7ced30a4a7a8b90a0bab 296 Gene3D G3DSA:1.10.1040.10 165 292 5.1E-40 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS09415 3db08741e71e7ced30a4a7a8b90a0bab 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 162 8.2E-49 T 13-09-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 THL1_RS09415 3db08741e71e7ced30a4a7a8b90a0bab 296 SUPERFAMILY SSF51735 2 162 1.31E-43 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS09415 3db08741e71e7ced30a4a7a8b90a0bab 296 Gene3D G3DSA:3.40.50.720 1 162 3.4E-55 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS09415 3db08741e71e7ced30a4a7a8b90a0bab 296 PIRSF PIRSF000103 1 291 4.3E-72 T 13-09-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 THL1_RS09415 3db08741e71e7ced30a4a7a8b90a0bab 296 SUPERFAMILY SSF48179 164 291 5.1E-37 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS09415 3db08741e71e7ced30a4a7a8b90a0bab 296 PANTHER PTHR22981:SF70 1 296 3.7E-128 T 13-09-2016 THL1_RS09415 3db08741e71e7ced30a4a7a8b90a0bab 296 PANTHER PTHR22981 1 296 3.7E-128 T 13-09-2016 THL1_RS18515 fb3593da2474d275cb367328f3d492cc 328 Gene3D G3DSA:3.40.50.300 6 160 1.7E-49 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18515 fb3593da2474d275cb367328f3d492cc 328 SUPERFAMILY SSF52540 5 203 1.32E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18515 fb3593da2474d275cb367328f3d492cc 328 PANTHER PTHR11669:SF8 20 214 1.7E-56 T 13-09-2016 THL1_RS18515 fb3593da2474d275cb367328f3d492cc 328 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 14 200 1.4E-61 T 13-09-2016 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS18515 fb3593da2474d275cb367328f3d492cc 328 PANTHER PTHR11669 20 214 1.7E-56 T 13-09-2016 THL1_RS18515 fb3593da2474d275cb367328f3d492cc 328 Pfam PF09115 DNA polymerase III, delta subunit, C terminal 210 321 8.5E-7 T 13-09-2016 IPR015199 DNA polymerase III, delta subunit, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS18515 fb3593da2474d275cb367328f3d492cc 328 Pfam PF13177 DNA polymerase III, delta subunit 18 159 2.3E-45 T 13-09-2016 THL1_RS15620 03ac40b9b06be9f8d413fb2db6a1d084 342 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 27 208 9.9E-39 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS15620 03ac40b9b06be9f8d413fb2db6a1d084 342 PANTHER PTHR11019:SF75 122 342 3.5E-35 T 13-09-2016 THL1_RS15620 03ac40b9b06be9f8d413fb2db6a1d084 342 SUPERFAMILY SSF46689 287 335 4.93E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15620 03ac40b9b06be9f8d413fb2db6a1d084 342 Gene3D G3DSA:1.10.10.60 287 335 4.1E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15620 03ac40b9b06be9f8d413fb2db6a1d084 342 SMART SM00342 251 334 1.3E-19 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS15620 03ac40b9b06be9f8d413fb2db6a1d084 342 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 303 318 8.2E-6 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS15620 03ac40b9b06be9f8d413fb2db6a1d084 342 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 318 334 8.2E-6 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS15620 03ac40b9b06be9f8d413fb2db6a1d084 342 PANTHER PTHR11019 122 342 3.5E-35 T 13-09-2016 THL1_RS15620 03ac40b9b06be9f8d413fb2db6a1d084 342 Pfam PF12833 Helix-turn-helix domain 259 335 3.9E-14 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 350 409 1.8E-13 T 13-09-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 Gene3D G3DSA:2.40.50.180 621 683 1.1E-14 T 13-09-2016 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 Gene3D G3DSA:3.30.565.10 411 596 3.3E-37 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 Gene3D G3DSA:2.30.30.40 684 727 7.7E-24 T 13-09-2016 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 Gene3D G3DSA:2.30.30.40 597 618 7.7E-24 T 13-09-2016 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 Gene3D G3DSA:1.20.120.160 4 144 1.3E-44 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 SUPERFAMILY SSF55874 412 595 4.98E-39 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 SUPERFAMILY SSF47384 350 410 1.06E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 SMART SM01231 349 409 6.4E-19 T 13-09-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 Pfam PF01584 CheW-like domain 603 730 1.1E-24 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 SMART SM00387 454 597 2.4E-23 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 Pfam PF01627 Hpt domain 8 100 3.0E-18 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 SUPERFAMILY SSF47226 6 127 5.89E-32 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 SMART SM00260 589 728 8.5E-41 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 PRINTS PR00344 Bacterial sensor protein C-terminal signature 541 551 2.2E-11 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 PRINTS PR00344 Bacterial sensor protein C-terminal signature 581 594 2.2E-11 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 PRINTS PR00344 Bacterial sensor protein C-terminal signature 499 513 2.2E-11 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 PRINTS PR00344 Bacterial sensor protein C-terminal signature 557 575 2.2E-11 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 SMART SM00073 6 103 2.7E-18 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 PANTHER PTHR22617:SF6 193 735 4.7E-278 T 13-09-2016 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 PANTHER PTHR22617 193 735 4.7E-278 T 13-09-2016 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 PANTHER PTHR22617 1 152 4.7E-278 T 13-09-2016 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 PANTHER PTHR22617:SF6 1 152 4.7E-278 T 13-09-2016 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 Gene3D G3DSA:1.10.287.560 349 410 1.2E-19 T 13-09-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 SUPERFAMILY SSF50341 596 728 1.31E-32 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS19495 72db99210fc7908e36dde503cf634dcf 735 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 457 596 6.3E-17 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS20660 31021dbc7a5f43bcc16f6da3c7f8ae6a 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 256 9.9E-49 T 13-09-2016 THL1_RS20660 31021dbc7a5f43bcc16f6da3c7f8ae6a 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.0E-8 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20660 31021dbc7a5f43bcc16f6da3c7f8ae6a 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.0E-8 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20660 31021dbc7a5f43bcc16f6da3c7f8ae6a 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.0E-8 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20660 31021dbc7a5f43bcc16f6da3c7f8ae6a 260 PANTHER PTHR24322 157 192 1.1E-41 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20660 31021dbc7a5f43bcc16f6da3c7f8ae6a 260 PANTHER PTHR24322 11 30 1.1E-41 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20660 31021dbc7a5f43bcc16f6da3c7f8ae6a 260 PANTHER PTHR24322 46 141 1.1E-41 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20660 31021dbc7a5f43bcc16f6da3c7f8ae6a 260 SUPERFAMILY SSF51735 5 258 6.67E-62 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20660 31021dbc7a5f43bcc16f6da3c7f8ae6a 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.7E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20660 31021dbc7a5f43bcc16f6da3c7f8ae6a 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.7E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20660 31021dbc7a5f43bcc16f6da3c7f8ae6a 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.7E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20660 31021dbc7a5f43bcc16f6da3c7f8ae6a 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.7E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20660 31021dbc7a5f43bcc16f6da3c7f8ae6a 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.7E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20660 31021dbc7a5f43bcc16f6da3c7f8ae6a 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.7E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20660 31021dbc7a5f43bcc16f6da3c7f8ae6a 260 Gene3D G3DSA:3.40.50.720 2 257 1.2E-66 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20660 31021dbc7a5f43bcc16f6da3c7f8ae6a 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 SMART SM00388 418 483 3.9E-18 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 PANTHER PTHR24423:SF559 397 795 2.5E-178 T 13-09-2016 THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 SUPERFAMILY SSF47384 406 484 2.94E-18 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 Pfam PF00512 His Kinase A (phospho-acceptor) domain 419 483 4.8E-16 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 Pfam PF07696 7TMR-DISM extracellular 2 31 171 7.1E-36 T 13-09-2016 IPR011622 7TM-DISM receptor, extracellular domain, type 2 THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 SMART SM00448 670 783 2.8E-37 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 PANTHER PTHR24423 397 795 2.5E-178 T 13-09-2016 THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 530 645 3.3E-18 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 Pfam PF07695 7TM diverse intracellular signalling 184 386 1.2E-55 T 13-09-2016 IPR011623 7TM-DISM receptor, extracellular domain, type 1 THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 Gene3D G3DSA:3.40.50.2300 666 787 2.7E-42 T 13-09-2016 THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 SUPERFAMILY SSF55874 472 647 1.7E-35 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 Pfam PF00072 Response regulator receiver domain 672 783 1.6E-27 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 Gene3D G3DSA:3.30.565.10 487 649 1.9E-36 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 SMART SM00387 530 646 1.9E-23 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 PANTHER PTHR24423:SF559 35 50 2.5E-178 T 13-09-2016 THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 SUPERFAMILY SSF52172 669 787 6.55E-40 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 Gene3D G3DSA:1.10.287.130 410 478 4.4E-15 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 PANTHER PTHR24423 35 50 2.5E-178 T 13-09-2016 THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 PRINTS PR00344 Bacterial sensor protein C-terminal signature 630 643 4.5E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 PRINTS PR00344 Bacterial sensor protein C-terminal signature 606 624 4.5E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS04355 9e50a14ed44be5d01349ce1e2a4cf595 799 PRINTS PR00344 Bacterial sensor protein C-terminal signature 571 585 4.5E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 SMART SM00956 404 507 5.4E-48 T 13-09-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 SUPERFAMILY SSF52540 200 446 4.49E-60 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 SMART SM00487 14 210 2.9E-30 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 Gene3D G3DSA:3.40.50.300 198 335 2.3E-48 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 Gene3D G3DSA:3.40.50.300 5 194 1.8E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 Gene3D G3DSA:1.10.10.10 606 639 1.5E-4 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 Pfam PF09382 RQC domain 401 509 1.1E-35 T 13-09-2016 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 Pfam PF16124 RecQ zinc-binding 335 396 8.6E-19 T 13-09-2016 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 PANTHER PTHR13710:SF81 1 595 6.4E-279 T 13-09-2016 THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 SMART SM00490 242 323 2.5E-23 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 Gene3D G3DSA:1.10.10.10 336 510 3.4E-57 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 Gene3D G3DSA:1.10.150.80 528 595 3.4E-19 T 13-09-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 SUPERFAMILY SSF52540 5 189 5.76E-42 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 SUPERFAMILY SSF47819 523 601 1.22E-22 T 13-09-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 8 456 5.6E-153 T 13-09-2016 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 Pfam PF00570 HRDC domain 529 594 1.3E-22 T 13-09-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 Pfam PF00270 DEAD/DEAH box helicase 21 180 1.9E-17 T 13-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 6 594 6.0E-245 T 13-09-2016 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 PANTHER PTHR13710 1 595 6.4E-279 T 13-09-2016 THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 SMART SM00341 524 604 4.9E-17 T 13-09-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 THL1_RS09370 b6a499cbd16dc4d243cb5d45f71fc71b 707 Pfam PF00271 Helicase conserved C-terminal domain 219 323 4.0E-14 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS09120 00aba93408ee8f4eddb26bec3075efe0 284 PIRSF PIRSF001365 1 284 2.7E-75 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS09120 00aba93408ee8f4eddb26bec3075efe0 284 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 5.9E-17 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS09120 00aba93408ee8f4eddb26bec3075efe0 284 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 5.9E-17 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS09120 00aba93408ee8f4eddb26bec3075efe0 284 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 5.9E-17 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS09120 00aba93408ee8f4eddb26bec3075efe0 284 SUPERFAMILY SSF51569 1 283 1.57E-82 T 13-09-2016 THL1_RS09120 00aba93408ee8f4eddb26bec3075efe0 284 PANTHER PTHR12128:SF34 4 284 3.0E-88 T 13-09-2016 THL1_RS09120 00aba93408ee8f4eddb26bec3075efe0 284 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 282 47.698 T 13-09-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS09120 00aba93408ee8f4eddb26bec3075efe0 284 Gene3D G3DSA:3.20.20.70 3 283 1.1E-89 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS09120 00aba93408ee8f4eddb26bec3075efe0 284 Pfam PF00701 Dihydrodipicolinate synthetase family 4 282 2.2E-62 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS09120 00aba93408ee8f4eddb26bec3075efe0 284 SMART SM01130 3 284 1.0E-101 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS09120 00aba93408ee8f4eddb26bec3075efe0 284 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 7 281 4.0E-75 T 13-09-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS09120 00aba93408ee8f4eddb26bec3075efe0 284 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 13-09-2016 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS09120 00aba93408ee8f4eddb26bec3075efe0 284 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 39 56 - T 13-09-2016 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS09120 00aba93408ee8f4eddb26bec3075efe0 284 PANTHER PTHR12128 4 284 3.0E-88 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS25035 1064d8705be2ed0e8ec17ca0b449af46 362 PIRSF PIRSF015761 21 362 2.2E-21 T 13-09-2016 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 THL1_RS25035 1064d8705be2ed0e8ec17ca0b449af46 362 Pfam PF05134 Type II secretion system (T2SS), protein L 6 168 1.8E-20 T 13-09-2016 IPR024230 GspL, cytoplasmic actin-ATPase-like domain THL1_RS25035 1064d8705be2ed0e8ec17ca0b449af46 362 SUPERFAMILY SSF53067 4 137 1.07E-22 T 13-09-2016 THL1_RS25035 1064d8705be2ed0e8ec17ca0b449af46 362 Pfam PF12693 GspL periplasmic domain 211 361 7.3E-14 T 13-09-2016 IPR025691 GspL periplasmic domain THL1_RS23350 dc4ff92f917156645f8c9717f9aef5e4 301 Pfam PF12483 E3 Ubiquitin ligase 83 182 9.9E-6 T 13-09-2016 IPR022170 Mitochondrial ubiquitin ligase activator of NFKB 1 GO:0004842|GO:0007005 KEGG: 00220+6.3.2.-|KEGG: 00261+6.3.2.-|KEGG: 00380+6.3.2.-|UniPathway: UPA00143 THL1_RS23350 dc4ff92f917156645f8c9717f9aef5e4 301 ProSitePatterns PS00018 EF-hand calcium-binding domain. 211 223 - T 13-09-2016 IPR018247 EF-Hand 1, calcium-binding site THL1_RS13525 4886e26b47b13627e1debda490f60456 440 PRINTS PR00344 Bacterial sensor protein C-terminal signature 369 383 4.2E-6 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS13525 4886e26b47b13627e1debda490f60456 440 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 417 4.2E-6 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS13525 4886e26b47b13627e1debda490f60456 440 SMART SM00388 225 289 2.2E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS13525 4886e26b47b13627e1debda490f60456 440 Gene3D G3DSA:3.30.565.10 317 436 2.6E-23 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS13525 4886e26b47b13627e1debda490f60456 440 PANTHER PTHR24423 163 432 3.3E-49 T 13-09-2016 THL1_RS13525 4886e26b47b13627e1debda490f60456 440 Pfam PF00512 His Kinase A (phospho-acceptor) domain 227 288 4.4E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS13525 4886e26b47b13627e1debda490f60456 440 Pfam PF08521 Two-component sensor kinase N-terminal 16 146 5.6E-10 T 13-09-2016 IPR013727 Two-component sensor kinase, N-terminal THL1_RS13525 4886e26b47b13627e1debda490f60456 440 Gene3D G3DSA:1.10.287.130 217 285 5.5E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS13525 4886e26b47b13627e1debda490f60456 440 PANTHER PTHR24423:SF474 163 432 3.3E-49 T 13-09-2016 THL1_RS13525 4886e26b47b13627e1debda490f60456 440 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 342 431 9.9E-14 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS13525 4886e26b47b13627e1debda490f60456 440 SUPERFAMILY SSF47384 208 287 1.96E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS13525 4886e26b47b13627e1debda490f60456 440 SUPERFAMILY SSF55874 318 427 3.67E-23 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS13525 4886e26b47b13627e1debda490f60456 440 SMART SM00387 334 438 1.5E-18 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS02560 c039ab53b5559eaeef36018d28d376a9 180 PANTHER PTHR20941 6 165 2.8E-70 T 13-09-2016 THL1_RS02560 c039ab53b5559eaeef36018d28d376a9 180 Gene3D G3DSA:3.30.70.560 6 151 2.9E-34 T 13-09-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 THL1_RS02560 c039ab53b5559eaeef36018d28d376a9 180 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 7 130 1.0E-21 T 13-09-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 THL1_RS02560 c039ab53b5559eaeef36018d28d376a9 180 SUPERFAMILY SSF55083 5 152 8.5E-37 T 13-09-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 THL1_RS02560 c039ab53b5559eaeef36018d28d376a9 180 PANTHER PTHR20941:SF12 6 165 2.8E-70 T 13-09-2016 THL1_RS02560 c039ab53b5559eaeef36018d28d376a9 180 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 7 130 4.5E-22 T 13-09-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 THL1_RS25490 5793ca7e3313999f531da77fea3fc33c 106 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 69 86 4.4E-10 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS25490 5793ca7e3313999f531da77fea3fc33c 106 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 86 106 4.4E-10 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS25490 5793ca7e3313999f531da77fea3fc33c 106 Pfam PF02954 Bacterial regulatory protein, Fis family 63 103 8.9E-14 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS25490 5793ca7e3313999f531da77fea3fc33c 106 Gene3D G3DSA:1.10.10.60 35 105 7.3E-24 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS25490 5793ca7e3313999f531da77fea3fc33c 106 PRINTS PR01591 DNA-binding protein FIS signature 50 65 4.9E-11 T 13-09-2016 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 THL1_RS25490 5793ca7e3313999f531da77fea3fc33c 106 PRINTS PR01591 DNA-binding protein FIS signature 34 50 4.9E-11 T 13-09-2016 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 THL1_RS25490 5793ca7e3313999f531da77fea3fc33c 106 PRINTS PR01591 DNA-binding protein FIS signature 65 77 4.9E-11 T 13-09-2016 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 THL1_RS25490 5793ca7e3313999f531da77fea3fc33c 106 PIRSF PIRSF002097 8 106 7.1E-40 T 13-09-2016 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 THL1_RS25490 5793ca7e3313999f531da77fea3fc33c 106 SUPERFAMILY SSF46689 24 105 1.05E-21 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS25490 5793ca7e3313999f531da77fea3fc33c 106 PANTHER PTHR32071 27 105 2.7E-20 T 13-09-2016 THL1_RS09195 c7485d5bb98c20d785f90025975aad27 131 SUPERFAMILY SSF51316 1 129 1.99E-45 T 13-09-2016 IPR011057 Mss4-like THL1_RS09195 c7485d5bb98c20d785f90025975aad27 131 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 24 112 6.8E-19 T 13-09-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801|UniPathway: UPA00562 THL1_RS09195 c7485d5bb98c20d785f90025975aad27 131 PANTHER PTHR33337 1 128 4.2E-46 T 13-09-2016 THL1_RS09195 c7485d5bb98c20d785f90025975aad27 131 PANTHER PTHR33337:SF11 1 128 4.2E-46 T 13-09-2016 THL1_RS09195 c7485d5bb98c20d785f90025975aad27 131 Gene3D G3DSA:3.90.1590.10 2 128 4.4E-40 T 13-09-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801|UniPathway: UPA00562 THL1_RS28465 97bc71e6f93cb12220a0f67b561adee8 262 PANTHER PTHR13696 1 261 3.3E-90 T 13-09-2016 THL1_RS28465 97bc71e6f93cb12220a0f67b561adee8 262 Pfam PF13614 AAA domain 3 178 5.0E-63 T 13-09-2016 IPR025669 AAA domain THL1_RS28465 97bc71e6f93cb12220a0f67b561adee8 262 SUPERFAMILY SSF52540 1 253 9.83E-67 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28465 97bc71e6f93cb12220a0f67b561adee8 262 PANTHER PTHR13696:SF52 1 261 3.3E-90 T 13-09-2016 THL1_RS28465 97bc71e6f93cb12220a0f67b561adee8 262 Gene3D G3DSA:3.40.50.300 3 255 6.5E-70 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04270 6c37284bd95e1373d4c270407a6ad136 436 Gene3D G3DSA:1.10.530.10 109 166 3.4E-56 T 13-09-2016 THL1_RS04270 6c37284bd95e1373d4c270407a6ad136 436 Gene3D G3DSA:1.10.530.10 247 361 3.4E-56 T 13-09-2016 THL1_RS04270 6c37284bd95e1373d4c270407a6ad136 436 SUPERFAMILY SSF47090 365 433 8.89E-17 T 13-09-2016 IPR002477 Peptidoglycan binding-like THL1_RS04270 6c37284bd95e1373d4c270407a6ad136 436 SUPERFAMILY SSF53955 53 361 2.06E-101 T 13-09-2016 IPR023346 Lysozyme-like domain THL1_RS04270 6c37284bd95e1373d4c270407a6ad136 436 Pfam PF13406 Transglycosylase SLT domain 65 355 4.1E-110 T 13-09-2016 IPR031304 Transglycosylase SLT domain 2 THL1_RS04270 6c37284bd95e1373d4c270407a6ad136 436 PANTHER PTHR30163 52 435 4.5E-158 T 13-09-2016 IPR011757 Lytic transglycosylase MltB THL1_RS04270 6c37284bd95e1373d4c270407a6ad136 436 PANTHER PTHR30163:SF2 52 435 4.5E-158 T 13-09-2016 THL1_RS04270 6c37284bd95e1373d4c270407a6ad136 436 Pfam PF01471 Putative peptidoglycan binding domain 378 432 2.9E-12 T 13-09-2016 IPR002477 Peptidoglycan binding-like THL1_RS04270 6c37284bd95e1373d4c270407a6ad136 436 Gene3D G3DSA:1.10.101.10 377 433 9.0E-13 T 13-09-2016 IPR002477 Peptidoglycan binding-like THL1_RS04270 6c37284bd95e1373d4c270407a6ad136 436 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 65 359 7.8E-114 T 13-09-2016 IPR011970 Lytic murein transglycosylase THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 SMART SM00388 261 326 2.8E-20 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 SUPERFAMILY SSF47226 633 745 1.44E-17 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 Gene3D G3DSA:1.20.120.160 631 744 8.3E-18 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 Gene3D G3DSA:3.40.50.2300 505 628 4.2E-31 T 13-09-2016 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 SUPERFAMILY SSF52172 505 629 1.71E-31 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 SUPERFAMILY SSF47384 246 326 1.08E-18 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 Pfam PF01627 Hpt domain 657 734 1.2E-7 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 374 487 8.1E-31 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 467 2.4E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 428 2.4E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 442 2.4E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 486 2.4E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 Pfam PF00072 Response regulator receiver domain 508 621 3.6E-22 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 PANTHER PTHR24423:SF382 39 68 1.4E-129 T 13-09-2016 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 Pfam PF00512 His Kinase A (phospho-acceptor) domain 261 326 5.9E-18 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 SMART SM00387 373 489 2.8E-37 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 Pfam PF17149 Periplasmic sensor domain found in signal transduction proteins 37 143 3.4E-16 T 13-09-2016 IPR033414 Periplasmic sensor domain UniPathway: UPA00073 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 Pfam PF00672 HAMP domain 151 223 6.1E-13 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 PANTHER PTHR24423 39 68 1.4E-129 T 13-09-2016 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 Gene3D G3DSA:3.30.565.10 329 487 9.4E-43 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 Gene3D G3DSA:1.10.287.130 253 322 2.4E-15 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 SUPERFAMILY SSF55874 315 485 2.1E-42 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 PANTHER PTHR24423 240 622 1.4E-129 T 13-09-2016 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 SMART SM00448 506 621 2.9E-28 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS19795 957c8d498a95bbe9a70bc53315d5b421 748 PANTHER PTHR24423:SF382 240 622 1.4E-129 T 13-09-2016 THL1_RS26345 4b0e221b7eedfbb8bac3ab357e499ab0 266 SUPERFAMILY SSF50199 29 173 6.54E-30 T 13-09-2016 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold THL1_RS26345 4b0e221b7eedfbb8bac3ab357e499ab0 266 PANTHER PTHR12302:SF0 31 177 2.7E-33 T 13-09-2016 THL1_RS26345 4b0e221b7eedfbb8bac3ab357e499ab0 266 Pfam PF00565 Staphylococcal nuclease homologue 58 165 4.2E-18 T 13-09-2016 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold THL1_RS26345 4b0e221b7eedfbb8bac3ab357e499ab0 266 PANTHER PTHR12302 31 177 2.7E-33 T 13-09-2016 THL1_RS26345 4b0e221b7eedfbb8bac3ab357e499ab0 266 SMART SM00318 35 166 3.1E-17 T 13-09-2016 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold THL1_RS26345 4b0e221b7eedfbb8bac3ab357e499ab0 266 Gene3D G3DSA:2.40.50.90 38 167 2.4E-24 T 13-09-2016 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold THL1_RS13450 d58e82f3952807cc073317d4ab558fe3 271 Pfam PF07722 Peptidase C26 16 234 1.3E-67 T 13-09-2016 IPR011697 Peptidase C26 GO:0006541|GO:0016787 THL1_RS13450 d58e82f3952807cc073317d4ab558fe3 271 PANTHER PTHR11922 45 80 7.5E-54 T 13-09-2016 THL1_RS13450 d58e82f3952807cc073317d4ab558fe3 271 PANTHER PTHR11922:SF18 96 269 7.5E-54 T 13-09-2016 THL1_RS13450 d58e82f3952807cc073317d4ab558fe3 271 PANTHER PTHR11922 96 269 7.5E-54 T 13-09-2016 THL1_RS13450 d58e82f3952807cc073317d4ab558fe3 271 PANTHER PTHR11922:SF18 45 80 7.5E-54 T 13-09-2016 THL1_RS13450 d58e82f3952807cc073317d4ab558fe3 271 SUPERFAMILY SSF52317 38 259 2.75E-40 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS13450 d58e82f3952807cc073317d4ab558fe3 271 Gene3D G3DSA:3.40.50.880 28 262 4.0E-48 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS04310 c4339f25ae9cc6a5927ff0984f665747 279 PANTHER PTHR22777 18 277 3.4E-117 T 13-09-2016 THL1_RS04310 c4339f25ae9cc6a5927ff0984f665747 279 Gene3D G3DSA:3.30.465.10 192 277 7.0E-27 T 13-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THL1_RS04310 c4339f25ae9cc6a5927ff0984f665747 279 Gene3D G3DSA:3.10.580.10 51 191 6.8E-19 T 13-09-2016 THL1_RS04310 c4339f25ae9cc6a5927ff0984f665747 279 SUPERFAMILY SSF56176 198 277 6.54E-22 T 13-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THL1_RS04310 c4339f25ae9cc6a5927ff0984f665747 279 SMART SM01091 200 278 3.9E-29 T 13-09-2016 IPR005170 Transporter-associated domain THL1_RS04310 c4339f25ae9cc6a5927ff0984f665747 279 Pfam PF00571 CBS domain 136 184 1.0E-5 T 13-09-2016 IPR000644 CBS domain THL1_RS04310 c4339f25ae9cc6a5927ff0984f665747 279 PANTHER PTHR22777:SF17 18 277 3.4E-117 T 13-09-2016 THL1_RS04310 c4339f25ae9cc6a5927ff0984f665747 279 SMART SM00116 136 184 1.5 T 13-09-2016 IPR000644 CBS domain THL1_RS04310 c4339f25ae9cc6a5927ff0984f665747 279 SMART SM00116 72 121 15.0 T 13-09-2016 IPR000644 CBS domain THL1_RS04310 c4339f25ae9cc6a5927ff0984f665747 279 Pfam PF03471 Transporter associated domain 202 276 1.8E-20 T 13-09-2016 IPR005170 Transporter-associated domain THL1_RS04310 c4339f25ae9cc6a5927ff0984f665747 279 SUPERFAMILY SSF54631 60 198 1.52E-31 T 13-09-2016 THL1_RS26790 88be7307232a1038ff42d6246dfec5f8 407 Pfam PF13356 Domain of unknown function (DUF4102) 8 92 4.1E-22 T 13-09-2016 IPR025166 Domain of unknown function DUF4102 THL1_RS26790 88be7307232a1038ff42d6246dfec5f8 407 Gene3D G3DSA:1.10.443.10 214 383 7.8E-27 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS26790 88be7307232a1038ff42d6246dfec5f8 407 Pfam PF00589 Phage integrase family 215 375 1.3E-21 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS26790 88be7307232a1038ff42d6246dfec5f8 407 PANTHER PTHR30629 2 392 1.7E-140 T 13-09-2016 THL1_RS26790 88be7307232a1038ff42d6246dfec5f8 407 SUPERFAMILY SSF56349 103 385 3.24E-66 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS26790 88be7307232a1038ff42d6246dfec5f8 407 PANTHER PTHR30629:SF3 2 392 1.7E-140 T 13-09-2016 THL1_RS26790 88be7307232a1038ff42d6246dfec5f8 407 Gene3D G3DSA:1.10.150.130 103 197 1.1E-18 T 13-09-2016 IPR023109 Integrase/recombinase, N-terminal THL1_RS26790 88be7307232a1038ff42d6246dfec5f8 407 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 104 156 1.3E-5 T 13-09-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THL1_RS08615 f4ef2fee771d9b71134a7ca6780623ea 197 PANTHER PTHR31573 9 197 3.9E-83 T 13-09-2016 IPR032852 DNA oxidative demethylase ALKBH2 GO:0006281 THL1_RS08615 f4ef2fee771d9b71134a7ca6780623ea 197 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 16 194 1.4E-35 T 13-09-2016 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like THL1_RS08615 f4ef2fee771d9b71134a7ca6780623ea 197 PANTHER PTHR31573:SF1 9 197 3.9E-83 T 13-09-2016 THL1_RS08615 f4ef2fee771d9b71134a7ca6780623ea 197 Gene3D G3DSA:2.60.120.590 16 196 5.4E-39 T 13-09-2016 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like THL1_RS08615 f4ef2fee771d9b71134a7ca6780623ea 197 SUPERFAMILY SSF51197 9 196 2.2E-67 T 13-09-2016 THL1_RS28490 f5d681313285bca8b5e7fb029580df8d 81 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 24.504 T 13-09-2016 IPR002696 Putative membrane protein insertion efficiency factor THL1_RS28490 f5d681313285bca8b5e7fb029580df8d 81 PANTHER PTHR33383 1 72 3.0E-39 T 13-09-2016 THL1_RS28490 f5d681313285bca8b5e7fb029580df8d 81 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 7 77 1.5E-26 T 13-09-2016 IPR002696 Putative membrane protein insertion efficiency factor THL1_RS28490 f5d681313285bca8b5e7fb029580df8d 81 SMART SM01234 1 68 1.5E-44 T 13-09-2016 IPR002696 Putative membrane protein insertion efficiency factor THL1_RS28490 f5d681313285bca8b5e7fb029580df8d 81 Pfam PF01809 Haemolytic domain 3 68 7.6E-30 T 13-09-2016 IPR002696 Putative membrane protein insertion efficiency factor THL1_RS28490 f5d681313285bca8b5e7fb029580df8d 81 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 1.0E-14 T 13-09-2016 IPR002696 Putative membrane protein insertion efficiency factor THL1_RS00750 1a59e85f27cf4062559ecb8475779a5c 306 SUPERFAMILY SSF52540 29 268 4.98E-58 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00750 1a59e85f27cf4062559ecb8475779a5c 306 PANTHER PTHR32071 28 270 3.7E-106 T 13-09-2016 THL1_RS00750 1a59e85f27cf4062559ecb8475779a5c 306 SMART SM00382 48 190 2.1E-6 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS00750 1a59e85f27cf4062559ecb8475779a5c 306 Gene3D G3DSA:1.10.8.60 200 271 3.7E-23 T 13-09-2016 THL1_RS00750 1a59e85f27cf4062559ecb8475779a5c 306 Gene3D G3DSA:3.40.50.300 32 199 6.8E-46 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00750 1a59e85f27cf4062559ecb8475779a5c 306 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 113 128 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS00750 1a59e85f27cf4062559ecb8475779a5c 306 Pfam PF00158 Sigma-54 interaction domain 32 190 2.3E-52 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS00750 1a59e85f27cf4062559ecb8475779a5c 306 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 52 65 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS12180 c01c409ee14ad4e36e0d260922824295 319 SUPERFAMILY SSF82282 7 314 5.76E-66 T 13-09-2016 IPR003726 Homocysteine-binding domain THL1_RS12180 c01c409ee14ad4e36e0d260922824295 319 Pfam PF02574 Homocysteine S-methyltransferase 17 310 1.1E-38 T 13-09-2016 IPR003726 Homocysteine-binding domain THL1_RS12180 c01c409ee14ad4e36e0d260922824295 319 PANTHER PTHR11103:SF7 1 309 2.1E-51 T 13-09-2016 THL1_RS12180 c01c409ee14ad4e36e0d260922824295 319 Gene3D G3DSA:3.20.20.330 5 313 2.1E-51 T 13-09-2016 IPR003726 Homocysteine-binding domain THL1_RS12180 c01c409ee14ad4e36e0d260922824295 319 PANTHER PTHR11103 1 309 2.1E-51 T 13-09-2016 THL1_RS25000 2ecb5f8f68f561e9e7f5979ad09c0493 494 SUPERFAMILY SSF160246 5 69 2.62E-13 T 13-09-2016 THL1_RS25000 2ecb5f8f68f561e9e7f5979ad09c0493 494 Pfam PF00437 Type II/IV secretion system protein 122 386 6.4E-84 T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS25000 2ecb5f8f68f561e9e7f5979ad09c0493 494 PANTHER PTHR30258:SF9 7 494 1.7E-268 T 13-09-2016 THL1_RS25000 2ecb5f8f68f561e9e7f5979ad09c0493 494 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 7 491 1.5E-206 T 13-09-2016 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 THL1_RS25000 2ecb5f8f68f561e9e7f5979ad09c0493 494 Gene3D G3DSA:3.30.450.90 89 219 2.2E-52 T 13-09-2016 THL1_RS25000 2ecb5f8f68f561e9e7f5979ad09c0493 494 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 314 328 - T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS25000 2ecb5f8f68f561e9e7f5979ad09c0493 494 PANTHER PTHR30258 7 494 1.7E-268 T 13-09-2016 THL1_RS25000 2ecb5f8f68f561e9e7f5979ad09c0493 494 Gene3D G3DSA:3.40.50.300 225 492 4.4E-97 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25000 2ecb5f8f68f561e9e7f5979ad09c0493 494 SUPERFAMILY SSF52540 102 491 6.28E-99 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08360 b03cd2638b8812b9d810ff99a41830fb 109 SUPERFAMILY SSF103481 12 108 4.71E-16 T 13-09-2016 THL1_RS08360 b03cd2638b8812b9d810ff99a41830fb 109 PANTHER PTHR30561 5 109 6.0E-60 T 13-09-2016 THL1_RS08360 b03cd2638b8812b9d810ff99a41830fb 109 Pfam PF00893 Small Multidrug Resistance protein 7 99 2.8E-26 T 13-09-2016 IPR000390 Small multidrug resistance protein family GO:0016021 THL1_RS08360 b03cd2638b8812b9d810ff99a41830fb 109 PANTHER PTHR30561:SF6 5 109 6.0E-60 T 13-09-2016 IPR023737 Spermidine export protein MdtI GO:0005886|GO:0015606|GO:0015848 THL1_RS11250 c37f28c51c9c1a6947fc46348c663005 341 Pfam PF01734 Patatin-like phospholipase 7 164 2.9E-14 T 13-09-2016 IPR002641 Patatin/Phospholipase A2-related GO:0006629 THL1_RS11250 c37f28c51c9c1a6947fc46348c663005 341 Gene3D G3DSA:3.40.1090.10 7 166 2.7E-6 T 13-09-2016 THL1_RS11250 c37f28c51c9c1a6947fc46348c663005 341 PANTHER PTHR14226:SF24 3 185 8.3E-95 T 13-09-2016 THL1_RS11250 c37f28c51c9c1a6947fc46348c663005 341 PANTHER PTHR14226:SF24 238 339 8.3E-95 T 13-09-2016 THL1_RS11250 c37f28c51c9c1a6947fc46348c663005 341 PANTHER PTHR14226 238 339 8.3E-95 T 13-09-2016 THL1_RS11250 c37f28c51c9c1a6947fc46348c663005 341 PANTHER PTHR14226 3 185 8.3E-95 T 13-09-2016 THL1_RS11250 c37f28c51c9c1a6947fc46348c663005 341 SUPERFAMILY SSF52151 256 337 3.14E-49 T 13-09-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THL1_RS11250 c37f28c51c9c1a6947fc46348c663005 341 SUPERFAMILY SSF52151 3 210 3.14E-49 T 13-09-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THL1_RS02335 9da706494fbc6408571ce55b0c03b16c 350 Pfam PF13416 Bacterial extracellular solute-binding protein 44 312 4.3E-36 T 13-09-2016 THL1_RS02335 9da706494fbc6408571ce55b0c03b16c 350 Gene3D G3DSA:3.40.190.10 135 274 9.9E-17 T 13-09-2016 THL1_RS02335 9da706494fbc6408571ce55b0c03b16c 350 PANTHER PTHR30222:SF9 30 349 7.4E-126 T 13-09-2016 THL1_RS02335 9da706494fbc6408571ce55b0c03b16c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 124 140 3.1E-40 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02335 9da706494fbc6408571ce55b0c03b16c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 34 50 3.1E-40 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02335 9da706494fbc6408571ce55b0c03b16c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 93 106 3.1E-40 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02335 9da706494fbc6408571ce55b0c03b16c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 252 271 3.1E-40 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02335 9da706494fbc6408571ce55b0c03b16c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 77 91 3.1E-40 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02335 9da706494fbc6408571ce55b0c03b16c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 50 71 3.1E-40 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02335 9da706494fbc6408571ce55b0c03b16c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 171 190 3.1E-40 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02335 9da706494fbc6408571ce55b0c03b16c 350 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 208 227 3.1E-40 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02335 9da706494fbc6408571ce55b0c03b16c 350 Gene3D G3DSA:3.40.190.10 275 309 1.5E-50 T 13-09-2016 THL1_RS02335 9da706494fbc6408571ce55b0c03b16c 350 Gene3D G3DSA:3.40.190.10 29 133 1.5E-50 T 13-09-2016 THL1_RS02335 9da706494fbc6408571ce55b0c03b16c 350 PIRSF PIRSF019574 2 350 5.1E-104 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02335 9da706494fbc6408571ce55b0c03b16c 350 PANTHER PTHR30222 30 349 7.4E-126 T 13-09-2016 THL1_RS02335 9da706494fbc6408571ce55b0c03b16c 350 SUPERFAMILY SSF53850 29 349 1.56E-82 T 13-09-2016 THL1_RS26295 81f1b94b4e083b9b1ea8b335e44f0d9e 163 PRINTS PR01100 Shikimate kinase family signature 19 32 1.0E-14 T 13-09-2016 THL1_RS26295 81f1b94b4e083b9b1ea8b335e44f0d9e 163 PRINTS PR01100 Shikimate kinase family signature 47 55 1.0E-14 T 13-09-2016 THL1_RS26295 81f1b94b4e083b9b1ea8b335e44f0d9e 163 PRINTS PR01100 Shikimate kinase family signature 86 103 1.0E-14 T 13-09-2016 THL1_RS26295 81f1b94b4e083b9b1ea8b335e44f0d9e 163 PRINTS PR01100 Shikimate kinase family signature 65 74 1.0E-14 T 13-09-2016 THL1_RS26295 81f1b94b4e083b9b1ea8b335e44f0d9e 163 PANTHER PTHR21087 1 159 2.7E-63 T 13-09-2016 THL1_RS26295 81f1b94b4e083b9b1ea8b335e44f0d9e 163 Pfam PF01202 Shikimate kinase 1 157 1.6E-56 T 13-09-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS26295 81f1b94b4e083b9b1ea8b335e44f0d9e 163 ProSitePatterns PS01128 Shikimate kinase signature. 48 73 - T 13-09-2016 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS26295 81f1b94b4e083b9b1ea8b335e44f0d9e 163 Gene3D G3DSA:3.40.50.300 1 159 1.4E-52 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26295 81f1b94b4e083b9b1ea8b335e44f0d9e 163 SUPERFAMILY SSF52540 1 157 3.45E-30 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26295 81f1b94b4e083b9b1ea8b335e44f0d9e 163 Hamap MF_00109 Shikimate kinase [aroK]. 1 158 25.296 T 13-09-2016 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS13785 7702e03fe1d3d5c00a60c45f8dc699b7 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 253 3.0E-60 T 13-09-2016 THL1_RS13785 7702e03fe1d3d5c00a60c45f8dc699b7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 2.9E-34 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13785 7702e03fe1d3d5c00a60c45f8dc699b7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.9E-34 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13785 7702e03fe1d3d5c00a60c45f8dc699b7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.9E-34 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13785 7702e03fe1d3d5c00a60c45f8dc699b7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.9E-34 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13785 7702e03fe1d3d5c00a60c45f8dc699b7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 2.9E-34 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13785 7702e03fe1d3d5c00a60c45f8dc699b7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.9E-34 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13785 7702e03fe1d3d5c00a60c45f8dc699b7 258 SUPERFAMILY SSF51735 10 253 5.22E-74 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS13785 7702e03fe1d3d5c00a60c45f8dc699b7 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 8.0E-6 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13785 7702e03fe1d3d5c00a60c45f8dc699b7 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 8.0E-6 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13785 7702e03fe1d3d5c00a60c45f8dc699b7 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 8.0E-6 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13785 7702e03fe1d3d5c00a60c45f8dc699b7 258 PANTHER PTHR24321 7 257 8.1E-58 T 13-09-2016 THL1_RS13785 7702e03fe1d3d5c00a60c45f8dc699b7 258 PANTHER PTHR24321:SF6 7 257 8.1E-58 T 13-09-2016 THL1_RS13785 7702e03fe1d3d5c00a60c45f8dc699b7 258 Gene3D G3DSA:3.40.50.720 5 253 6.0E-78 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18830 960798bd22b908e2f01112a7098e18c8 479 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 13 443 1.5E-112 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS18830 960798bd22b908e2f01112a7098e18c8 479 PANTHER PTHR10422:SF21 5 468 0.0 T 13-09-2016 THL1_RS18830 960798bd22b908e2f01112a7098e18c8 479 PANTHER PTHR10422 5 468 0.0 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS18830 960798bd22b908e2f01112a7098e18c8 479 SUPERFAMILY SSF81442 9 470 1.03E-123 T 13-09-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS18830 960798bd22b908e2f01112a7098e18c8 479 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 204 259 - T 13-09-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS18830 960798bd22b908e2f01112a7098e18c8 479 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 9 471 2.3E-226 T 13-09-2016 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS18830 960798bd22b908e2f01112a7098e18c8 479 Gene3D G3DSA:1.20.210.10 8 469 4.8E-71 T 13-09-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS04670 f4e35a51e73ed3ebbedb6664c67a6b29 374 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 303 309 - T 13-09-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THL1_RS04670 f4e35a51e73ed3ebbedb6664c67a6b29 374 SUPERFAMILY SSF53335 200 356 2.63E-24 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS04670 f4e35a51e73ed3ebbedb6664c67a6b29 374 Hamap MF_01859 Ribosomal RNA large subunit methyltransferase G [rlmG]. 1 374 44.591 T 13-09-2016 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS04670 f4e35a51e73ed3ebbedb6664c67a6b29 374 PIRSF PIRSF037565 1 374 4.4E-143 T 13-09-2016 IPR017237 rRNA (guanine-N2-)-methyltransferase, RsmD GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS04670 f4e35a51e73ed3ebbedb6664c67a6b29 374 PANTHER PTHR18895:SF6 81 374 1.9E-132 T 13-09-2016 THL1_RS04670 f4e35a51e73ed3ebbedb6664c67a6b29 374 Pfam PF05175 Methyltransferase small domain 201 371 5.9E-52 T 13-09-2016 IPR007848 Methyltransferase small domain GO:0008168 THL1_RS04670 f4e35a51e73ed3ebbedb6664c67a6b29 374 SUPERFAMILY SSF53335 57 162 3.22E-6 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS04670 f4e35a51e73ed3ebbedb6664c67a6b29 374 PANTHER PTHR18895 81 374 1.9E-132 T 13-09-2016 THL1_RS04670 f4e35a51e73ed3ebbedb6664c67a6b29 374 Gene3D G3DSA:3.40.50.150 229 349 3.3E-19 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS13655 ccd4a8d224c851d3c9dff6b057d96a59 560 Gene3D G3DSA:3.40.50.1220 187 336 1.1E-35 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS13655 ccd4a8d224c851d3c9dff6b057d96a59 560 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 426 445 - T 13-09-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 THL1_RS13655 ccd4a8d224c851d3c9dff6b057d96a59 560 Gene3D G3DSA:3.40.50.970 6 178 5.1E-63 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS13655 ccd4a8d224c851d3c9dff6b057d96a59 560 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 174 3.6E-55 T 13-09-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 THL1_RS13655 ccd4a8d224c851d3c9dff6b057d96a59 560 PANTHER PTHR18968 1 560 5.2E-273 T 13-09-2016 THL1_RS13655 ccd4a8d224c851d3c9dff6b057d96a59 560 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 197 328 7.5E-29 T 13-09-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 THL1_RS13655 ccd4a8d224c851d3c9dff6b057d96a59 560 PANTHER PTHR18968:SF120 1 560 5.2E-273 T 13-09-2016 THL1_RS13655 ccd4a8d224c851d3c9dff6b057d96a59 560 Gene3D G3DSA:3.40.50.970 364 548 1.9E-64 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS13655 ccd4a8d224c851d3c9dff6b057d96a59 560 SUPERFAMILY SSF52518 366 545 1.34E-61 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS13655 ccd4a8d224c851d3c9dff6b057d96a59 560 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 390 536 3.9E-44 T 13-09-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THL1_RS13655 ccd4a8d224c851d3c9dff6b057d96a59 560 SUPERFAMILY SSF52467 161 362 4.3E-38 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS13655 ccd4a8d224c851d3c9dff6b057d96a59 560 SUPERFAMILY SSF52518 8 178 4.63E-54 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS14280 0fa963b1708fb4464e63a71fd716ac8a 613 SUPERFAMILY SSF53474 357 613 2.15E-58 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS14280 0fa963b1708fb4464e63a71fd716ac8a 613 Pfam PF00326 Prolyl oligopeptidase family 407 612 6.9E-41 T 13-09-2016 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 THL1_RS14280 0fa963b1708fb4464e63a71fd716ac8a 613 PANTHER PTHR11731 45 260 4.9E-118 T 13-09-2016 THL1_RS14280 0fa963b1708fb4464e63a71fd716ac8a 613 PANTHER PTHR11731 285 613 4.9E-118 T 13-09-2016 THL1_RS14280 0fa963b1708fb4464e63a71fd716ac8a 613 Gene3D G3DSA:2.120.10.60 118 259 1.6E-5 T 13-09-2016 THL1_RS14280 0fa963b1708fb4464e63a71fd716ac8a 613 PANTHER PTHR11731:SF75 45 260 4.9E-118 T 13-09-2016 THL1_RS14280 0fa963b1708fb4464e63a71fd716ac8a 613 PANTHER PTHR11731:SF75 285 613 4.9E-118 T 13-09-2016 THL1_RS14280 0fa963b1708fb4464e63a71fd716ac8a 613 Gene3D G3DSA:3.40.50.1820 305 611 1.6E-60 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS14280 0fa963b1708fb4464e63a71fd716ac8a 613 SUPERFAMILY SSF82171 54 289 1.08E-7 T 13-09-2016 THL1_RS25445 3b29ad5f982b6feec153db8586917a5c 535 SUPERFAMILY SSF52172 245 376 6.69E-31 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS25445 3b29ad5f982b6feec153db8586917a5c 535 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 373 534 2.0E-47 T 13-09-2016 IPR000160 GGDEF domain THL1_RS25445 3b29ad5f982b6feec153db8586917a5c 535 SUPERFAMILY SSF55073 381 534 3.53E-48 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS25445 3b29ad5f982b6feec153db8586917a5c 535 SUPERFAMILY SSF52172 132 242 3.42E-9 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS25445 3b29ad5f982b6feec153db8586917a5c 535 Gene3D G3DSA:3.40.50.2300 247 373 8.9E-29 T 13-09-2016 THL1_RS25445 3b29ad5f982b6feec153db8586917a5c 535 PANTHER PTHR10799 265 535 6.1E-33 T 13-09-2016 THL1_RS25445 3b29ad5f982b6feec153db8586917a5c 535 Gene3D G3DSA:3.40.50.2300 135 244 9.3E-9 T 13-09-2016 THL1_RS25445 3b29ad5f982b6feec153db8586917a5c 535 Pfam PF00072 Response regulator receiver domain 251 362 1.0E-22 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS25445 3b29ad5f982b6feec153db8586917a5c 535 Pfam PF00072 Response regulator receiver domain 134 237 2.0E-5 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS25445 3b29ad5f982b6feec153db8586917a5c 535 SMART SM00448 123 237 0.23 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS25445 3b29ad5f982b6feec153db8586917a5c 535 SMART SM00448 249 362 7.3E-28 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS25445 3b29ad5f982b6feec153db8586917a5c 535 PANTHER PTHR10799:SF710 265 535 6.1E-33 T 13-09-2016 THL1_RS25445 3b29ad5f982b6feec153db8586917a5c 535 Gene3D G3DSA:3.30.70.270 378 534 4.0E-52 T 13-09-2016 THL1_RS25445 3b29ad5f982b6feec153db8586917a5c 535 SMART SM00267 365 535 1.5E-49 T 13-09-2016 IPR000160 GGDEF domain THL1_RS25445 3b29ad5f982b6feec153db8586917a5c 535 Pfam PF00990 Diguanylate cyclase, GGDEF domain 378 532 2.3E-43 T 13-09-2016 IPR000160 GGDEF domain THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 253 2.3E-17 T 13-09-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 SUPERFAMILY SSF53738 257 364 4.71E-30 T 13-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 6 443 3.7E-192 T 13-09-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 95 104 - T 13-09-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 SUPERFAMILY SSF53738 155 256 1.49E-30 T 13-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 SUPERFAMILY SSF55957 357 445 3.27E-20 T 13-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 372 441 3.2E-12 T 13-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 Gene3D G3DSA:3.40.120.10 250 366 1.5E-32 T 13-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 134 3.7E-44 T 13-09-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 Gene3D G3DSA:3.40.120.10 3 152 3.3E-46 T 13-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 SUPERFAMILY SSF53738 2 180 1.45E-47 T 13-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 Gene3D G3DSA:3.40.120.10 175 249 4.1E-26 T 13-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 2.7E-14 T 13-09-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 2.7E-14 T 13-09-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 2.7E-14 T 13-09-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 PANTHER PTHR22573 2 445 4.4E-173 T 13-09-2016 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 Gene3D G3DSA:3.30.310.50 368 445 6.9E-17 T 13-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 363 1.1E-30 T 13-09-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 2 444 47.045 T 13-09-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS24430 220aae6a3f2206fc796e1ac34d3df1fd 446 PANTHER PTHR22573:SF15 2 445 4.4E-173 T 13-09-2016 THL1_RS18050 6e134811c3bac9eeda1121236f0d66af 200 PIRSF PIRSF020736 1 200 6.3E-87 T 13-09-2016 IPR010386 tRNA-hydroxylase MiaE KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.-|UniPathway: UPA00729 THL1_RS18050 6e134811c3bac9eeda1121236f0d66af 200 PANTHER PTHR42637 3 200 5.7E-69 T 13-09-2016 THL1_RS18050 6e134811c3bac9eeda1121236f0d66af 200 Gene3D G3DSA:1.20.1260.10 3 199 1.1E-82 T 13-09-2016 IPR012347 Ferritin-related THL1_RS18050 6e134811c3bac9eeda1121236f0d66af 200 SUPERFAMILY SSF47240 3 199 8.11E-73 T 13-09-2016 IPR009078 Ferritin-like superfamily THL1_RS18050 6e134811c3bac9eeda1121236f0d66af 200 PANTHER PTHR42637:SF1 3 200 5.7E-69 T 13-09-2016 THL1_RS18050 6e134811c3bac9eeda1121236f0d66af 200 Pfam PF06175 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) 3 53 1.3E-13 T 13-09-2016 IPR010386 tRNA-hydroxylase MiaE KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.-|UniPathway: UPA00729 THL1_RS18050 6e134811c3bac9eeda1121236f0d66af 200 Pfam PF06175 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) 54 196 5.3E-61 T 13-09-2016 IPR010386 tRNA-hydroxylase MiaE KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.-|UniPathway: UPA00729 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3289 3307 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF48113 735 819 1.01E-112 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF48113 387 458 1.01E-112 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF48113 488 687 1.01E-112 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF48113 161 287 1.01E-112 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF48113 37 118 1.01E-112 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF51120 3244 3373 5.23E-18 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 897 915 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3190 3208 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2373 2391 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 PANTHER PTHR11475:SF4 29 44 3.6E-31 T 13-09-2016 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 PANTHER PTHR11475:SF4 2211 2290 3.6E-31 T 13-09-2016 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 PANTHER PTHR11475:SF4 1870 1914 3.6E-31 T 13-09-2016 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 PANTHER PTHR11475:SF4 1947 2163 3.6E-31 T 13-09-2016 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 PANTHER PTHR11475 29 44 3.6E-31 T 13-09-2016 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 PANTHER PTHR11475 1870 1914 3.6E-31 T 13-09-2016 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 PANTHER PTHR11475 1947 2163 3.6E-31 T 13-09-2016 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF03098 Animal haem peroxidase 414 815 5.6E-54 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF03098 Animal haem peroxidase 1878 2283 3.1E-50 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF03098 Animal haem peroxidase 1498 1712 3.8E-12 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF03098 Animal haem peroxidase 42 266 6.1E-10 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3298 3316 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF51120 895 1082 6.45E-8 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF51120 1111 1141 6.45E-8 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF51120 2631 2653 3.49E-8 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF51120 2488 2585 3.49E-8 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3019 3037 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2364 2382 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Gene3D G3DSA:2.150.10.10 3260 3371 4.4E-15 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Gene3D G3DSA:2.150.10.10 2350 2470 2.2E-19 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Gene3D G3DSA:2.150.10.10 883 1075 2.2E-21 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Gene3D G3DSA:2.150.10.10 2567 2581 1.0E-14 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Gene3D G3DSA:2.150.10.10 3012 3087 1.0E-14 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Gene3D G3DSA:2.150.10.10 2616 2658 1.0E-14 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Gene3D G3DSA:2.150.10.10 2487 2530 1.0E-14 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Gene3D G3DSA:2.150.10.10 3088 3259 1.5E-21 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Gene3D G3DSA:1.10.640.10 400 687 1.6E-125 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Gene3D G3DSA:1.10.640.10 735 819 1.6E-125 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Gene3D G3DSA:1.10.640.10 330 347 1.6E-125 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Gene3D G3DSA:1.10.640.10 178 271 1.6E-125 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Gene3D G3DSA:1.10.640.10 2207 2291 2.4E-119 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Gene3D G3DSA:1.10.640.10 1636 1714 2.4E-119 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Gene3D G3DSA:1.10.640.10 1775 1792 2.4E-119 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Gene3D G3DSA:1.10.640.10 1861 2159 2.4E-119 T 13-09-2016 IPR019791 Haem peroxidase, animal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF51120 3090 3261 1.83E-25 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3280 3298 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF51120 2982 3104 3.92E-13 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF51120 870 950 2.09E-13 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3110 3128 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF48113 2207 2292 4.95E-107 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF48113 1494 1576 4.95E-107 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF48113 1948 2159 4.95E-107 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF48113 1861 1918 4.95E-107 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF48113 1619 1733 4.95E-107 T 13-09-2016 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 SUPERFAMILY SSF51120 2330 2466 2.49E-15 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 PRINTS PR00313 NodO calcium binding signature 907 918 3.1E-5 T 13-09-2016 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 PRINTS PR00313 NodO calcium binding signature 919 927 3.1E-5 T 13-09-2016 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 PRINTS PR00313 NodO calcium binding signature 1188 1197 3.1E-5 T 13-09-2016 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 PRINTS PR00313 NodO calcium binding signature 937 945 3.1E-5 T 13-09-2016 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 PANTHER PTHR11475 2211 2290 3.6E-31 T 13-09-2016 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2397 2411 52.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1188 1204 13.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3015 3030 0.3 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2377 2393 2.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3031 3047 0.17 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3284 3300 0.39 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1031 1048 21.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3301 3318 4.3 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 910 926 0.057 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3096 3112 1.4 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2360 2375 0.11 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3151 3161 60.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3386 3398 5.4 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3113 3129 0.063 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3184 3201 0.021 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 930 944 11.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3203 3219 24.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 892 908 0.23 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2634 2650 23.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS19885 2be90aaa61e0fd7c5f5722ed2a78a1b3 3398 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 2439 2453 14.0 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS01950 52cf107008cbee46fb1f55bebea28c5b 263 Gene3D G3DSA:1.10.3720.10 9 261 7.7E-51 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01950 52cf107008cbee46fb1f55bebea28c5b 263 SUPERFAMILY SSF161098 4 259 1.83E-49 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01950 52cf107008cbee46fb1f55bebea28c5b 263 PANTHER PTHR30222:SF7 17 260 2.3E-43 T 13-09-2016 THL1_RS01950 52cf107008cbee46fb1f55bebea28c5b 263 PANTHER PTHR30222 17 260 2.3E-43 T 13-09-2016 THL1_RS01950 52cf107008cbee46fb1f55bebea28c5b 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 253 3.0E-15 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS03845 71055d53c05e017cece167537f3a4b3d 369 Gene3D G3DSA:3.40.140.10 5 130 1.1E-35 T 13-09-2016 THL1_RS03845 71055d53c05e017cece167537f3a4b3d 369 PANTHER PTHR11079 1 220 9.3E-70 T 13-09-2016 THL1_RS03845 71055d53c05e017cece167537f3a4b3d 369 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 148 363 2.5E-51 T 13-09-2016 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 THL1_RS03845 71055d53c05e017cece167537f3a4b3d 369 SUPERFAMILY SSF53597 147 362 4.28E-56 T 13-09-2016 IPR024072 Dihydrofolate reductase-like domain THL1_RS03845 71055d53c05e017cece167537f3a4b3d 369 PANTHER PTHR11079:SF10 1 220 9.3E-70 T 13-09-2016 THL1_RS03845 71055d53c05e017cece167537f3a4b3d 369 Pfam PF01872 RibD C-terminal domain 149 359 8.5E-47 T 13-09-2016 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 THL1_RS03845 71055d53c05e017cece167537f3a4b3d 369 Gene3D G3DSA:3.40.430.10 131 362 2.4E-70 T 13-09-2016 IPR024072 Dihydrofolate reductase-like domain THL1_RS03845 71055d53c05e017cece167537f3a4b3d 369 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 9 361 1.6E-117 T 13-09-2016 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525|UniPathway: UPA00275|UniPathway: UPA00275 THL1_RS03845 71055d53c05e017cece167537f3a4b3d 369 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 101 1.1E-20 T 13-09-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 THL1_RS03845 71055d53c05e017cece167537f3a4b3d 369 SUPERFAMILY SSF53927 5 146 8.53E-50 T 13-09-2016 IPR016193 Cytidine deaminase-like GO:0003824 THL1_RS03845 71055d53c05e017cece167537f3a4b3d 369 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 90 - T 13-09-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 THL1_RS03845 71055d53c05e017cece167537f3a4b3d 369 PIRSF PIRSF006769 1 367 5.6E-128 T 13-09-2016 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525|UniPathway: UPA00275|UniPathway: UPA00275 THL1_RS27960 de2a810c8f28cd1b9f638add5c3fd5f2 382 SUPERFAMILY SSF51905 192 321 4.81E-34 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27960 de2a810c8f28cd1b9f638add5c3fd5f2 382 SUPERFAMILY SSF51905 1 162 4.81E-34 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27960 de2a810c8f28cd1b9f638add5c3fd5f2 382 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 231 245 2.6E-15 T 13-09-2016 THL1_RS27960 de2a810c8f28cd1b9f638add5c3fd5f2 382 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 277 2.6E-15 T 13-09-2016 THL1_RS27960 de2a810c8f28cd1b9f638add5c3fd5f2 382 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 357 372 2.6E-15 T 13-09-2016 THL1_RS27960 de2a810c8f28cd1b9f638add5c3fd5f2 382 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.6E-15 T 13-09-2016 THL1_RS27960 de2a810c8f28cd1b9f638add5c3fd5f2 382 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 2.6E-15 T 13-09-2016 THL1_RS27960 de2a810c8f28cd1b9f638add5c3fd5f2 382 Gene3D G3DSA:3.50.50.60 107 300 1.1E-38 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27960 de2a810c8f28cd1b9f638add5c3fd5f2 382 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 6.2E-21 T 13-09-2016 THL1_RS27960 de2a810c8f28cd1b9f638add5c3fd5f2 382 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 6.2E-21 T 13-09-2016 THL1_RS27960 de2a810c8f28cd1b9f638add5c3fd5f2 382 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 6.2E-21 T 13-09-2016 THL1_RS27960 de2a810c8f28cd1b9f638add5c3fd5f2 382 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 6.2E-21 T 13-09-2016 THL1_RS27960 de2a810c8f28cd1b9f638add5c3fd5f2 382 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 6.2E-21 T 13-09-2016 THL1_RS27960 de2a810c8f28cd1b9f638add5c3fd5f2 382 PANTHER PTHR22912:SF130 3 376 4.7E-146 T 13-09-2016 THL1_RS27960 de2a810c8f28cd1b9f638add5c3fd5f2 382 Gene3D G3DSA:3.50.50.60 3 106 2.1E-16 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27960 de2a810c8f28cd1b9f638add5c3fd5f2 382 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 279 9.1E-49 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27960 de2a810c8f28cd1b9f638add5c3fd5f2 382 PANTHER PTHR22912 3 376 4.7E-146 T 13-09-2016 THL1_RS26950 f65cc15dc0a30a78f62d0638037f77f7 291 Gene3D G3DSA:3.30.420.10 157 290 1.9E-7 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS26950 f65cc15dc0a30a78f62d0638037f77f7 291 Pfam PF00665 Integrase core domain 129 259 5.2E-18 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS26950 f65cc15dc0a30a78f62d0638037f77f7 291 SUPERFAMILY SSF53098 156 290 4.55E-5 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS26950 f65cc15dc0a30a78f62d0638037f77f7 291 PANTHER PTHR35004 1 289 1.2E-77 T 13-09-2016 THL1_RS26950 f65cc15dc0a30a78f62d0638037f77f7 291 PANTHER PTHR35004:SF2 1 289 1.2E-77 T 13-09-2016 THL1_RS04080 a904bda981da8624ca15a116be573b1b 152 Gene3D G3DSA:3.40.630.30 1 146 1.5E-26 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS04080 a904bda981da8624ca15a116be573b1b 152 PANTHER PTHR23091 1 152 5.7E-18 T 13-09-2016 THL1_RS04080 a904bda981da8624ca15a116be573b1b 152 Pfam PF00583 Acetyltransferase (GNAT) family 57 137 9.9E-11 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS04080 a904bda981da8624ca15a116be573b1b 152 SUPERFAMILY SSF55729 1 147 1.12E-33 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS02665 2223148cb4d31f448961d0597290c1b9 415 PANTHER PTHR30193:SF8 3 71 1.8E-162 T 13-09-2016 THL1_RS02665 2223148cb4d31f448961d0597290c1b9 415 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 216 406 1.0E-9 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS02665 2223148cb4d31f448961d0597290c1b9 415 PANTHER PTHR30193 175 415 1.8E-162 T 13-09-2016 THL1_RS02665 2223148cb4d31f448961d0597290c1b9 415 PANTHER PTHR30193:SF8 175 415 1.8E-162 T 13-09-2016 THL1_RS02665 2223148cb4d31f448961d0597290c1b9 415 Gene3D G3DSA:1.10.3720.10 33 59 1.3E-46 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS02665 2223148cb4d31f448961d0597290c1b9 415 Gene3D G3DSA:1.10.3720.10 176 410 1.3E-46 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS02665 2223148cb4d31f448961d0597290c1b9 415 PANTHER PTHR30193 3 71 1.8E-162 T 13-09-2016 THL1_RS02665 2223148cb4d31f448961d0597290c1b9 415 SUPERFAMILY SSF161098 29 53 4.09E-44 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS02665 2223148cb4d31f448961d0597290c1b9 415 SUPERFAMILY SSF161098 167 406 4.09E-44 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS15660 b1db9dd10c7da37c239e82ce77ee7d95 516 PIRSF PIRSF006060 9 513 1.1E-44 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS15660 b1db9dd10c7da37c239e82ce77ee7d95 516 Pfam PF13520 Amino acid permease 35 482 1.7E-47 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS15660 b1db9dd10c7da37c239e82ce77ee7d95 516 PANTHER PTHR11785 1 494 6.7E-57 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS15660 b1db9dd10c7da37c239e82ce77ee7d95 516 PANTHER PTHR11785:SF286 1 494 6.7E-57 T 13-09-2016 THL1_RS01195 644ea9bcc88f61357667f09f8c1d97ad 457 PANTHER PTHR11564 146 457 4.5E-145 T 13-09-2016 THL1_RS01195 644ea9bcc88f61357667f09f8c1d97ad 457 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 181 451 2.1E-109 T 13-09-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 THL1_RS01195 644ea9bcc88f61357667f09f8c1d97ad 457 Pfam PF02881 SRP54-type protein, helical bundle domain 166 232 1.6E-14 T 13-09-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 THL1_RS01195 644ea9bcc88f61357667f09f8c1d97ad 457 SMART SM00962 251 452 7.9E-122 T 13-09-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 THL1_RS01195 644ea9bcc88f61357667f09f8c1d97ad 457 SUPERFAMILY SSF52540 205 455 1.74E-52 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01195 644ea9bcc88f61357667f09f8c1d97ad 457 SMART SM00382 250 430 1.7E-9 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS01195 644ea9bcc88f61357667f09f8c1d97ad 457 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 425 438 - T 13-09-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 THL1_RS01195 644ea9bcc88f61357667f09f8c1d97ad 457 Gene3D G3DSA:1.20.120.140 146 232 3.0E-31 T 13-09-2016 THL1_RS01195 644ea9bcc88f61357667f09f8c1d97ad 457 Gene3D G3DSA:3.40.50.300 249 451 5.3E-82 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01195 644ea9bcc88f61357667f09f8c1d97ad 457 SMART SM00963 155 236 1.3E-25 T 13-09-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 THL1_RS01195 644ea9bcc88f61357667f09f8c1d97ad 457 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 179 452 63.409 T 13-09-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 THL1_RS01195 644ea9bcc88f61357667f09f8c1d97ad 457 SUPERFAMILY SSF47364 150 230 1.83E-20 T 13-09-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 THL1_RS01195 644ea9bcc88f61357667f09f8c1d97ad 457 Pfam PF00448 SRP54-type protein, GTPase domain 252 451 4.7E-77 T 13-09-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 THL1_RS01195 644ea9bcc88f61357667f09f8c1d97ad 457 PANTHER PTHR11564:SF16 146 457 4.5E-145 T 13-09-2016 THL1_RS25765 637c5b87b294f9068818044f182040b1 766 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 22 694 49.735 T 13-09-2016 IPR022946 Uncharacterised protein family UPF0313 THL1_RS25765 637c5b87b294f9068818044f182040b1 766 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 23 643 7.9E-264 T 13-09-2016 IPR022946 Uncharacterised protein family UPF0313 THL1_RS25765 637c5b87b294f9068818044f182040b1 766 Pfam PF04055 Radical SAM superfamily 379 584 8.0E-22 T 13-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 THL1_RS25765 637c5b87b294f9068818044f182040b1 766 Pfam PF08497 Radical SAM N-terminal 23 378 8.4E-146 T 13-09-2016 IPR013704 Uncharacterised protein family UPF0313, N-terminal THL1_RS25765 637c5b87b294f9068818044f182040b1 766 SUPERFAMILY SSF102114 469 618 3.14E-13 T 13-09-2016 THL1_RS25765 637c5b87b294f9068818044f182040b1 766 SUPERFAMILY SSF102114 352 439 3.14E-13 T 13-09-2016 THL1_RS25765 637c5b87b294f9068818044f182040b1 766 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 379 399 - T 13-09-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 THL1_RS25765 637c5b87b294f9068818044f182040b1 766 PANTHER PTHR32331:SF3 2 729 0.0 T 13-09-2016 THL1_RS25765 637c5b87b294f9068818044f182040b1 766 PANTHER PTHR32331 2 729 0.0 T 13-09-2016 THL1_RS25765 637c5b87b294f9068818044f182040b1 766 SMART SM00729 375 628 2.4E-7 T 13-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THL1_RS25765 637c5b87b294f9068818044f182040b1 766 Pfam PF11842 Domain of unknown function (DUF3362) 593 740 1.5E-51 T 13-09-2016 IPR024560 Uncharacterised protein family UPF0313, C-terminal THL1_RS25765 637c5b87b294f9068818044f182040b1 766 Gene3D G3DSA:3.80.30.20 373 629 2.5E-49 T 13-09-2016 IPR023404 Radical SAM, alpha/beta horseshoe THL1_RS17430 e67c21f395802b727d53894561c93049 309 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 190 272 1.9E-36 T 13-09-2016 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal THL1_RS17430 e67c21f395802b727d53894561c93049 309 SUPERFAMILY SSF52402 3 184 4.26E-57 T 13-09-2016 THL1_RS17430 e67c21f395802b727d53894561c93049 309 Gene3D G3DSA:3.40.50.620 1 182 9.5E-65 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS17430 e67c21f395802b727d53894561c93049 309 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 253 279 - T 13-09-2016 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site THL1_RS17430 e67c21f395802b727d53894561c93049 309 PANTHER PTHR10909:SF294 104 305 5.5E-129 T 13-09-2016 THL1_RS17430 e67c21f395802b727d53894561c93049 309 SMART SM00893 3 182 1.4E-56 T 13-09-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 THL1_RS17430 e67c21f395802b727d53894561c93049 309 Gene3D G3DSA:3.40.50.1220 184 309 7.1E-62 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS17430 e67c21f395802b727d53894561c93049 309 PIRSF PIRSF000089 1 309 2.2E-106 T 13-09-2016 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 THL1_RS17430 e67c21f395802b727d53894561c93049 309 PANTHER PTHR10909 104 305 5.5E-129 T 13-09-2016 THL1_RS17430 e67c21f395802b727d53894561c93049 309 SUPERFAMILY SSF52467 187 309 6.08E-49 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS17430 e67c21f395802b727d53894561c93049 309 Pfam PF01012 Electron transfer flavoprotein domain 3 168 9.2E-41 T 13-09-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 THL1_RS24230 4639d3e3ba6f377341685f680a3d5b86 266 Gene3D G3DSA:2.60.120.10 151 259 4.0E-29 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS24230 4639d3e3ba6f377341685f680a3d5b86 266 SMART SM00100 128 246 1.3E-18 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS24230 4639d3e3ba6f377341685f680a3d5b86 266 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 160 176 - T 13-09-2016 IPR018488 Cyclic nucleotide-binding, conserved site THL1_RS24230 4639d3e3ba6f377341685f680a3d5b86 266 SUPERFAMILY SSF51206 151 258 9.82E-28 T 13-09-2016 IPR018490 Cyclic nucleotide-binding-like THL1_RS24230 4639d3e3ba6f377341685f680a3d5b86 266 Pfam PF00027 Cyclic nucleotide-binding domain 152 234 2.1E-21 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS24230 4639d3e3ba6f377341685f680a3d5b86 266 PRINTS PR00103 cAMP-dependent protein kinase signature 154 168 4.1E-6 T 13-09-2016 THL1_RS24230 4639d3e3ba6f377341685f680a3d5b86 266 PRINTS PR00103 cAMP-dependent protein kinase signature 206 217 4.1E-6 T 13-09-2016 THL1_RS24230 4639d3e3ba6f377341685f680a3d5b86 266 PRINTS PR00103 cAMP-dependent protein kinase signature 169 183 4.1E-6 T 13-09-2016 THL1_RS24230 4639d3e3ba6f377341685f680a3d5b86 266 PRINTS PR00103 cAMP-dependent protein kinase signature 194 203 4.1E-6 T 13-09-2016 THL1_RS24230 4639d3e3ba6f377341685f680a3d5b86 266 PANTHER PTHR24567 145 266 2.0E-17 T 13-09-2016 THL1_RS20365 7f2edc8ba071aa68c1b353420e4657d8 617 SUPERFAMILY SSF49503 116 197 1.35E-7 T 13-09-2016 IPR008972 Cupredoxin THL1_RS20365 7f2edc8ba071aa68c1b353420e4657d8 617 SUPERFAMILY SSF49503 233 276 1.35E-7 T 13-09-2016 IPR008972 Cupredoxin THL1_RS20365 7f2edc8ba071aa68c1b353420e4657d8 617 Pfam PF07731 Multicopper oxidase 486 608 2.6E-13 T 13-09-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 THL1_RS20365 7f2edc8ba071aa68c1b353420e4657d8 617 SUPERFAMILY SSF49503 574 609 1.57E-14 T 13-09-2016 IPR008972 Cupredoxin THL1_RS20365 7f2edc8ba071aa68c1b353420e4657d8 617 SUPERFAMILY SSF49503 293 407 1.57E-14 T 13-09-2016 IPR008972 Cupredoxin THL1_RS20365 7f2edc8ba071aa68c1b353420e4657d8 617 SUPERFAMILY SSF49503 470 603 4.14E-17 T 13-09-2016 IPR008972 Cupredoxin THL1_RS20365 7f2edc8ba071aa68c1b353420e4657d8 617 PANTHER PTHR11709:SF2 247 614 1.2E-43 T 13-09-2016 THL1_RS20365 7f2edc8ba071aa68c1b353420e4657d8 617 PANTHER PTHR11709:SF2 124 231 1.2E-43 T 13-09-2016 THL1_RS20365 7f2edc8ba071aa68c1b353420e4657d8 617 ProSitePatterns PS00080 Multicopper oxidases signature 2. 588 599 - T 13-09-2016 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 THL1_RS20365 7f2edc8ba071aa68c1b353420e4657d8 617 PANTHER PTHR11709 247 614 1.2E-43 T 13-09-2016 THL1_RS20365 7f2edc8ba071aa68c1b353420e4657d8 617 PANTHER PTHR11709 124 231 1.2E-43 T 13-09-2016 THL1_RS20365 7f2edc8ba071aa68c1b353420e4657d8 617 Gene3D G3DSA:2.60.40.420 292 415 2.8E-21 T 13-09-2016 IPR008972 Cupredoxin THL1_RS20365 7f2edc8ba071aa68c1b353420e4657d8 617 Gene3D G3DSA:2.60.40.420 121 274 3.2E-9 T 13-09-2016 IPR008972 Cupredoxin THL1_RS20365 7f2edc8ba071aa68c1b353420e4657d8 617 Gene3D G3DSA:2.60.40.420 470 609 1.6E-22 T 13-09-2016 IPR008972 Cupredoxin THL1_RS08315 b5f8997e0dfb286779c10cce5c2856a5 326 ProSitePatterns PS00356 LacI-type HTH domain signature. 3 21 - T 13-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 THL1_RS08315 b5f8997e0dfb286779c10cce5c2856a5 326 Gene3D G3DSA:3.40.50.2300 61 166 9.6E-27 T 13-09-2016 THL1_RS08315 b5f8997e0dfb286779c10cce5c2856a5 326 SUPERFAMILY SSF53822 61 317 5.5E-48 T 13-09-2016 IPR028082 Periplasmic binding protein-like I THL1_RS08315 b5f8997e0dfb286779c10cce5c2856a5 326 TIGRFAM TIGR02417 fruct_sucro_rep: D-fructose-responsive transcription factor 2 326 2.5E-124 T 13-09-2016 IPR012781 D-fructose-responsive transcription factor GO:0003677|GO:0006355|GO:0009750 THL1_RS08315 b5f8997e0dfb286779c10cce5c2856a5 326 PANTHER PTHR30146 1 326 2.5E-153 T 13-09-2016 THL1_RS08315 b5f8997e0dfb286779c10cce5c2856a5 326 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 50 5.6E-17 T 13-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 THL1_RS08315 b5f8997e0dfb286779c10cce5c2856a5 326 SMART SM00354 1 73 1.1E-26 T 13-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 THL1_RS08315 b5f8997e0dfb286779c10cce5c2856a5 326 SUPERFAMILY SSF47413 2 58 5.06E-14 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS08315 b5f8997e0dfb286779c10cce5c2856a5 326 Gene3D G3DSA:3.40.50.2300 167 326 3.9E-32 T 13-09-2016 THL1_RS08315 b5f8997e0dfb286779c10cce5c2856a5 326 PANTHER PTHR30146:SF25 1 326 2.5E-153 T 13-09-2016 THL1_RS08315 b5f8997e0dfb286779c10cce5c2856a5 326 Gene3D G3DSA:1.10.260.40 2 60 4.9E-23 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS08315 b5f8997e0dfb286779c10cce5c2856a5 326 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 62 262 3.1E-21 T 13-09-2016 IPR001761 Periplasmic binding protein/LacI sugar binding domain THL1_RS25805 21d0d3f74edff7b7c32e5165a2651af2 248 Pfam PF00588 SpoU rRNA Methylase family 98 238 1.8E-39 T 13-09-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 THL1_RS25805 21d0d3f74edff7b7c32e5165a2651af2 248 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 4 245 42.699 T 13-09-2016 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB THL1_RS25805 21d0d3f74edff7b7c32e5165a2651af2 248 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 7 80 1.3E-19 T 13-09-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 THL1_RS25805 21d0d3f74edff7b7c32e5165a2651af2 248 PANTHER PTHR12029 3 247 4.0E-79 T 13-09-2016 THL1_RS25805 21d0d3f74edff7b7c32e5165a2651af2 248 SUPERFAMILY SSF75217 70 245 9.81E-48 T 13-09-2016 IPR029028 Alpha/beta knot methyltransferases THL1_RS25805 21d0d3f74edff7b7c32e5165a2651af2 248 Gene3D G3DSA:3.40.1280.10 93 246 1.8E-55 T 13-09-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THL1_RS25805 21d0d3f74edff7b7c32e5165a2651af2 248 Gene3D G3DSA:3.30.1330.30 1 77 7.0E-24 T 13-09-2016 IPR029064 50S ribosomal protein L30e-like THL1_RS25805 21d0d3f74edff7b7c32e5165a2651af2 248 SMART SM00967 6 81 8.9E-20 T 13-09-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 THL1_RS25805 21d0d3f74edff7b7c32e5165a2651af2 248 SUPERFAMILY SSF55315 2 77 1.88E-18 T 13-09-2016 IPR029064 50S ribosomal protein L30e-like THL1_RS25805 21d0d3f74edff7b7c32e5165a2651af2 248 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 4 244 8.1E-83 T 13-09-2016 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 THL1_RS28020 f7131d4abd84c1eff93b94365606b949 246 Gene3D G3DSA:1.20.58.220 129 241 4.4E-35 T 13-09-2016 THL1_RS28020 f7131d4abd84c1eff93b94365606b949 246 Gene3D G3DSA:1.20.58.220 10 120 2.3E-37 T 13-09-2016 THL1_RS28020 f7131d4abd84c1eff93b94365606b949 246 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 13 224 2.8E-79 T 13-09-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 THL1_RS28020 f7131d4abd84c1eff93b94365606b949 246 Pfam PF01895 PhoU domain 27 113 5.5E-23 T 13-09-2016 IPR026022 PhoU domain THL1_RS28020 f7131d4abd84c1eff93b94365606b949 246 Pfam PF01895 PhoU domain 131 214 4.1E-18 T 13-09-2016 IPR026022 PhoU domain THL1_RS28020 f7131d4abd84c1eff93b94365606b949 246 SUPERFAMILY SSF109755 13 232 7.01E-73 T 13-09-2016 THL1_RS28020 f7131d4abd84c1eff93b94365606b949 246 PANTHER PTHR10010:SF14 1 236 4.6E-91 T 13-09-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 THL1_RS28020 f7131d4abd84c1eff93b94365606b949 246 PIRSF PIRSF003107 8 229 8.2E-79 T 13-09-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 THL1_RS28020 f7131d4abd84c1eff93b94365606b949 246 PANTHER PTHR10010 1 236 4.6E-91 T 13-09-2016 THL1_RS09490 baf0f47e48c9f10bfebf55cc230103b3 309 SUPERFAMILY SSF88713 5 304 4.0E-97 T 13-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THL1_RS09490 baf0f47e48c9f10bfebf55cc230103b3 309 Pfam PF01522 Polysaccharide deacetylase 76 164 4.1E-18 T 13-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 THL1_RS09490 baf0f47e48c9f10bfebf55cc230103b3 309 PANTHER PTHR10587 10 302 5.9E-171 T 13-09-2016 THL1_RS09490 baf0f47e48c9f10bfebf55cc230103b3 309 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 5 303 1.5E-161 T 13-09-2016 IPR017625 Putative urate catabolism protein THL1_RS09490 baf0f47e48c9f10bfebf55cc230103b3 309 PANTHER PTHR10587:SF72 10 302 5.9E-171 T 13-09-2016 THL1_RS09490 baf0f47e48c9f10bfebf55cc230103b3 309 Gene3D G3DSA:3.20.20.370 4 305 4.1E-118 T 13-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 PANTHER PTHR24093:SF128 11 902 0.0 T 13-09-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 Gene3D G3DSA:1.20.1110.10 612 894 5.6E-66 T 13-09-2016 IPR023298 P-type ATPase, transmembrane domain THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 Gene3D G3DSA:1.20.1110.10 79 142 5.6E-66 T 13-09-2016 IPR023298 P-type ATPase, transmembrane domain THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 PANTHER PTHR24093 11 902 0.0 T 13-09-2016 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 SMART SM00831 26 99 1.2E-17 T 13-09-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 SUPERFAMILY SSF81665 274 367 1.27E-96 T 13-09-2016 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 SUPERFAMILY SSF81665 692 900 1.27E-96 T 13-09-2016 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 SUPERFAMILY SSF81665 30 148 1.27E-96 T 13-09-2016 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 375 381 - T 13-09-2016 IPR018303 P-type ATPase, phosphorylation site THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 Pfam PF00122 E1-E2 ATPase 115 364 6.3E-57 T 13-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 Gene3D G3DSA:3.40.1110.10 365 550 1.0E-31 T 13-09-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 SUPERFAMILY SSF56784 497 742 1.36E-35 T 13-09-2016 IPR023214 HAD-like domain THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 SUPERFAMILY SSF56784 371 391 1.36E-35 T 13-09-2016 IPR023214 HAD-like domain THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 Pfam PF00702 haloacid dehalogenase-like hydrolase 369 657 7.7E-21 T 13-09-2016 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 Pfam PF00690 Cation transporter/ATPase, N-terminus 28 94 4.1E-13 T 13-09-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 17 902 0.0 T 13-09-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 Pfam PF00689 Cation transporting ATPase, C-terminus 726 893 4.4E-15 T 13-09-2016 IPR006068 Cation-transporting P-type ATPase, C-terminal THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 PRINTS PR01836 Magnesium-transporting ATPase signature 856 877 5.0E-89 T 13-09-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 PRINTS PR01836 Magnesium-transporting ATPase signature 286 302 5.0E-89 T 13-09-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 PRINTS PR01836 Magnesium-transporting ATPase signature 719 730 5.0E-89 T 13-09-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 PRINTS PR01836 Magnesium-transporting ATPase signature 407 420 5.0E-89 T 13-09-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 PRINTS PR01836 Magnesium-transporting ATPase signature 701 716 5.0E-89 T 13-09-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 PRINTS PR01836 Magnesium-transporting ATPase signature 806 827 5.0E-89 T 13-09-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 PRINTS PR01836 Magnesium-transporting ATPase signature 751 764 5.0E-89 T 13-09-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 PRINTS PR01836 Magnesium-transporting ATPase signature 303 322 5.0E-89 T 13-09-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 PRINTS PR01836 Magnesium-transporting ATPase signature 771 787 5.0E-89 T 13-09-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 Gene3D G3DSA:2.70.150.10 42 78 8.8E-34 T 13-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 Gene3D G3DSA:2.70.150.10 143 274 8.8E-34 T 13-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 SUPERFAMILY SSF81653 163 273 1.31E-25 T 13-09-2016 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 616 732 1.4E-27 T 13-09-2016 IPR001757 P-type ATPase GO:0016021 THL1_RS25405 793bb62973b66d6c683cb75921abf605 903 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 268 589 5.8E-29 T 13-09-2016 IPR001757 P-type ATPase GO:0016021 THL1_RS20005 496eaef408522680dc94923c62c78c43 308 PIRSF PIRSF018266 3 307 3.4E-79 T 13-09-2016 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component THL1_RS20005 496eaef408522680dc94923c62c78c43 308 PANTHER PTHR30273:SF2 3 284 3.8E-50 T 13-09-2016 THL1_RS20005 496eaef408522680dc94923c62c78c43 308 Pfam PF16220 Domain of unknown function (DUF4880) 9 47 3.4E-9 T 13-09-2016 IPR032623 FecR, N-terminal THL1_RS20005 496eaef408522680dc94923c62c78c43 308 Pfam PF04773 FecR protein 105 195 3.0E-22 T 13-09-2016 IPR006860 FecR protein THL1_RS20005 496eaef408522680dc94923c62c78c43 308 PANTHER PTHR30273 3 284 3.8E-50 T 13-09-2016 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component THL1_RS20005 496eaef408522680dc94923c62c78c43 308 Pfam PF16344 Domain of unknown function (DUF4974) 228 284 5.1E-7 T 13-09-2016 IPR032508 Protein FecR, C-terminal THL1_RS12365 350e7e1976893c6821fb0741ac9a67e7 418 Gene3D G3DSA:3.40.718.10 14 418 8.0E-165 T 13-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 THL1_RS12365 350e7e1976893c6821fb0741ac9a67e7 418 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 31 414 3.7E-117 T 13-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 THL1_RS12365 350e7e1976893c6821fb0741ac9a67e7 418 PANTHER PTHR11835:SF52 190 257 3.5E-241 T 13-09-2016 THL1_RS12365 350e7e1976893c6821fb0741ac9a67e7 418 PANTHER PTHR11835:SF52 277 418 3.5E-241 T 13-09-2016 THL1_RS12365 350e7e1976893c6821fb0741ac9a67e7 418 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 305 324 - T 13-09-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 THL1_RS12365 350e7e1976893c6821fb0741ac9a67e7 418 SUPERFAMILY SSF53659 5 418 2.5E-147 T 13-09-2016 THL1_RS12365 350e7e1976893c6821fb0741ac9a67e7 418 PANTHER PTHR11835:SF52 3 166 3.5E-241 T 13-09-2016 THL1_RS12365 350e7e1976893c6821fb0741ac9a67e7 418 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 3 418 5.0E-223 T 13-09-2016 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 THL1_RS12365 350e7e1976893c6821fb0741ac9a67e7 418 PANTHER PTHR11835 3 166 3.5E-241 T 13-09-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 THL1_RS12365 350e7e1976893c6821fb0741ac9a67e7 418 SMART SM01329 30 414 2.7E-180 T 13-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 THL1_RS12365 350e7e1976893c6821fb0741ac9a67e7 418 PANTHER PTHR11835 190 257 3.5E-241 T 13-09-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 THL1_RS12365 350e7e1976893c6821fb0741ac9a67e7 418 PANTHER PTHR11835 277 418 3.5E-241 T 13-09-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 THL1_RS05280 479f2d0b6ed65f592c40fa622068ac97 481 PANTHER PTHR11659 2 481 3.9E-255 T 13-09-2016 IPR017959 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E GO:0016884 THL1_RS05280 479f2d0b6ed65f592c40fa622068ac97 481 PANTHER PTHR11659:SF0 2 481 3.9E-255 T 13-09-2016 THL1_RS05280 479f2d0b6ed65f592c40fa622068ac97 481 Gene3D G3DSA:1.10.10.410 436 479 6.3E-4 T 13-09-2016 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal THL1_RS05280 479f2d0b6ed65f592c40fa622068ac97 481 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 144 158 - T 13-09-2016 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 THL1_RS05280 479f2d0b6ed65f592c40fa622068ac97 481 Pfam PF02934 GatB/GatE catalytic domain 5 288 2.7E-112 T 13-09-2016 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 THL1_RS05280 479f2d0b6ed65f592c40fa622068ac97 481 Pfam PF02637 GatB domain 328 479 1.8E-51 T 13-09-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 THL1_RS05280 479f2d0b6ed65f592c40fa622068ac97 481 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 480 38.886 T 13-09-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 THL1_RS05280 479f2d0b6ed65f592c40fa622068ac97 481 SUPERFAMILY SSF55931 4 296 3.07E-121 T 13-09-2016 THL1_RS05280 479f2d0b6ed65f592c40fa622068ac97 481 SUPERFAMILY SSF89095 297 402 6.02E-36 T 13-09-2016 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 THL1_RS05280 479f2d0b6ed65f592c40fa622068ac97 481 SMART SM00845 328 479 1.9E-80 T 13-09-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 THL1_RS05280 479f2d0b6ed65f592c40fa622068ac97 481 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 2 479 9.4E-171 T 13-09-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 THL1_RS06755 17c6d0343cec4f6408ffd6ccee7a0cf0 238 PANTHER PTHR11751 121 143 7.5E-42 T 13-09-2016 THL1_RS06755 17c6d0343cec4f6408ffd6ccee7a0cf0 238 SMART SM00866 92 231 1.5E-29 T 13-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 THL1_RS06755 17c6d0343cec4f6408ffd6ccee7a0cf0 238 Pfam PF07702 UTRA domain 92 230 6.3E-38 T 13-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 THL1_RS06755 17c6d0343cec4f6408ffd6ccee7a0cf0 238 Gene3D G3DSA:1.10.10.10 11 67 5.0E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS06755 17c6d0343cec4f6408ffd6ccee7a0cf0 238 SUPERFAMILY SSF64288 59 235 5.65E-42 T 13-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain THL1_RS06755 17c6d0343cec4f6408ffd6ccee7a0cf0 238 SUPERFAMILY SSF46785 9 75 6.83E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS06755 17c6d0343cec4f6408ffd6ccee7a0cf0 238 SMART SM00345 12 71 2.1E-18 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS06755 17c6d0343cec4f6408ffd6ccee7a0cf0 238 PANTHER PTHR11751 12 74 7.5E-42 T 13-09-2016 THL1_RS06755 17c6d0343cec4f6408ffd6ccee7a0cf0 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 71 3.5E-17 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS06755 17c6d0343cec4f6408ffd6ccee7a0cf0 238 Gene3D G3DSA:3.40.1410.10 68 236 2.5E-43 T 13-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain THL1_RS06755 17c6d0343cec4f6408ffd6ccee7a0cf0 238 PANTHER PTHR11751:SF333 12 74 7.5E-42 T 13-09-2016 THL1_RS06755 17c6d0343cec4f6408ffd6ccee7a0cf0 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 2.1E-9 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS06755 17c6d0343cec4f6408ffd6ccee7a0cf0 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 2.1E-9 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS06755 17c6d0343cec4f6408ffd6ccee7a0cf0 238 PANTHER PTHR11751:SF333 121 143 7.5E-42 T 13-09-2016 THL1_RS25865 d47522cedc757407af06cc3b944d9749 324 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 8 315 29.992 T 13-09-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 THL1_RS25865 d47522cedc757407af06cc3b944d9749 324 SUPERFAMILY SSF52540 217 259 4.91E-5 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25865 d47522cedc757407af06cc3b944d9749 324 SUPERFAMILY SSF52540 6 41 4.91E-5 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25865 d47522cedc757407af06cc3b944d9749 324 Gene3D G3DSA:3.40.50.300 6 175 1.3E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25865 d47522cedc757407af06cc3b944d9749 324 Gene3D G3DSA:1.10.287.890 214 296 1.3E-32 T 13-09-2016 THL1_RS25865 d47522cedc757407af06cc3b944d9749 324 PANTHER PTHR11088 3 303 5.5E-112 T 13-09-2016 THL1_RS25865 d47522cedc757407af06cc3b944d9749 324 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 8 304 8.8E-102 T 13-09-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 THL1_RS25865 d47522cedc757407af06cc3b944d9749 324 Pfam PF01715 IPP transferase 42 298 3.1E-85 T 13-09-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 THL1_RS25865 d47522cedc757407af06cc3b944d9749 324 SUPERFAMILY SSF52540 9 153 1.36E-18 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15410 c35b8acf7332577562e73248620a91eb 392 PANTHER PTHR23518 8 391 1.0E-99 T 13-09-2016 THL1_RS15410 c35b8acf7332577562e73248620a91eb 392 Gene3D G3DSA:1.20.1250.20 217 389 6.8E-22 T 13-09-2016 THL1_RS15410 c35b8acf7332577562e73248620a91eb 392 Gene3D G3DSA:1.20.1250.20 12 195 7.8E-22 T 13-09-2016 THL1_RS15410 c35b8acf7332577562e73248620a91eb 392 PANTHER PTHR23518:SF2 8 391 1.0E-99 T 13-09-2016 THL1_RS15410 c35b8acf7332577562e73248620a91eb 392 Pfam PF07690 Major Facilitator Superfamily 19 355 7.2E-33 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS15410 c35b8acf7332577562e73248620a91eb 392 SUPERFAMILY SSF103473 9 390 9.94E-55 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS21835 feee8050bf3f1bd758996ff9c0a9a9ca 1464 PANTHER PTHR24031 21 390 1.6E-71 T 13-09-2016 THL1_RS21835 feee8050bf3f1bd758996ff9c0a9a9ca 1464 PANTHER PTHR24031 1368 1378 1.6E-71 T 13-09-2016 THL1_RS21835 feee8050bf3f1bd758996ff9c0a9a9ca 1464 PANTHER PTHR24031 413 438 1.6E-71 T 13-09-2016 THL1_RS21835 feee8050bf3f1bd758996ff9c0a9a9ca 1464 Gene3D G3DSA:3.40.50.300 260 389 1.0E-31 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21835 feee8050bf3f1bd758996ff9c0a9a9ca 1464 PANTHER PTHR24031:SF336 21 390 1.6E-71 T 13-09-2016 THL1_RS21835 feee8050bf3f1bd758996ff9c0a9a9ca 1464 Pfam PF00270 DEAD/DEAH box helicase 31 216 9.8E-24 T 13-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THL1_RS21835 feee8050bf3f1bd758996ff9c0a9a9ca 1464 SMART SM00487 26 251 3.1E-30 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS21835 feee8050bf3f1bd758996ff9c0a9a9ca 1464 Pfam PF08494 DEAD/H associated 653 855 9.1E-54 T 13-09-2016 IPR013701 DEAD/H associated GO:0005524|GO:0016818 THL1_RS21835 feee8050bf3f1bd758996ff9c0a9a9ca 1464 PANTHER PTHR24031:SF336 1368 1378 1.6E-71 T 13-09-2016 THL1_RS21835 feee8050bf3f1bd758996ff9c0a9a9ca 1464 PANTHER PTHR24031:SF336 413 438 1.6E-71 T 13-09-2016 THL1_RS21835 feee8050bf3f1bd758996ff9c0a9a9ca 1464 Pfam PF00271 Helicase conserved C-terminal domain 266 372 7.9E-17 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS21835 feee8050bf3f1bd758996ff9c0a9a9ca 1464 SUPERFAMILY SSF52540 245 376 1.42E-45 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21835 feee8050bf3f1bd758996ff9c0a9a9ca 1464 SUPERFAMILY SSF52540 39 218 1.42E-45 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21835 feee8050bf3f1bd758996ff9c0a9a9ca 1464 SMART SM00490 292 376 7.4E-18 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS21835 feee8050bf3f1bd758996ff9c0a9a9ca 1464 Gene3D G3DSA:3.40.50.300 14 226 3.2E-37 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22620 b89b3a9f96975b8eb561b7bfa0f544f3 253 Gene3D G3DSA:3.40.1180.10 11 246 1.2E-99 T 13-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 THL1_RS22620 b89b3a9f96975b8eb561b7bfa0f544f3 253 SUPERFAMILY SSF64005 12 235 5.23E-85 T 13-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 THL1_RS22620 b89b3a9f96975b8eb561b7bfa0f544f3 253 PANTHER PTHR10291 12 252 7.4E-121 T 13-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 THL1_RS22620 b89b3a9f96975b8eb561b7bfa0f544f3 253 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 12 239 1.5E-90 T 13-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 THL1_RS22620 b89b3a9f96975b8eb561b7bfa0f544f3 253 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 185 202 - T 13-09-2016 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 THL1_RS22620 b89b3a9f96975b8eb561b7bfa0f544f3 253 Pfam PF01255 Putative undecaprenyl diphosphate synthase 19 239 9.3E-79 T 13-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 THL1_RS22620 b89b3a9f96975b8eb561b7bfa0f544f3 253 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 12 240 39.386 T 13-09-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 THL1_RS18255 161d4df349d3fe6825750ea20f72eb67 386 PANTHER PTHR23522 1 385 3.0E-120 T 13-09-2016 THL1_RS18255 161d4df349d3fe6825750ea20f72eb67 386 Gene3D G3DSA:1.20.1250.20 10 181 9.2E-18 T 13-09-2016 THL1_RS18255 161d4df349d3fe6825750ea20f72eb67 386 Gene3D G3DSA:1.20.1250.20 199 385 1.1E-28 T 13-09-2016 THL1_RS18255 161d4df349d3fe6825750ea20f72eb67 386 Pfam PF12832 MFS_1 like family 10 364 3.5E-83 T 13-09-2016 IPR024989 Major facilitator superfamily associated domain THL1_RS18255 161d4df349d3fe6825750ea20f72eb67 386 PIRSF PIRSF004925 4 386 4.1E-104 T 13-09-2016 IPR026032 Probable 3-phenylpropionic acid transporter THL1_RS18255 161d4df349d3fe6825750ea20f72eb67 386 PANTHER PTHR23522:SF3 1 385 3.0E-120 T 13-09-2016 THL1_RS18255 161d4df349d3fe6825750ea20f72eb67 386 SUPERFAMILY SSF103473 10 382 9.81E-47 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS04420 856633d4d04070469128e9141c836bb8 304 SUPERFAMILY SSF51556 2 285 8.85E-48 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS04420 856633d4d04070469128e9141c836bb8 304 Pfam PF04909 Amidohydrolase 60 282 8.4E-37 T 13-09-2016 IPR006680 Amidohydrolase-related GO:0016787 THL1_RS04420 856633d4d04070469128e9141c836bb8 304 Gene3D G3DSA:3.20.20.140 2 287 4.5E-49 T 13-09-2016 THL1_RS04420 856633d4d04070469128e9141c836bb8 304 PANTHER PTHR21240 79 292 1.2E-20 T 13-09-2016 THL1_RS14095 6d6298288dad02be43c142b0d088b4ca 458 Gene3D G3DSA:3.30.1330.90 11 157 1.2E-54 T 13-09-2016 IPR029009 Allosteric substrate binding domain THL1_RS14095 6d6298288dad02be43c142b0d088b4ca 458 Pfam PF03315 Serine dehydratase beta chain 4 156 2.5E-59 T 13-09-2016 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 THL1_RS14095 6d6298288dad02be43c142b0d088b4ca 458 SUPERFAMILY SSF143548 17 158 1.2E-46 T 13-09-2016 IPR029009 Allosteric substrate binding domain THL1_RS14095 6d6298288dad02be43c142b0d088b4ca 458 Pfam PF03313 Serine dehydratase alpha chain 188 452 3.4E-106 T 13-09-2016 IPR005130 Serine dehydratase-like, alpha subunit THL1_RS14095 6d6298288dad02be43c142b0d088b4ca 458 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 4 455 4.0E-220 T 13-09-2016 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 THL1_RS14095 6d6298288dad02be43c142b0d088b4ca 458 PANTHER PTHR30182:SF1 1 455 4.6E-246 T 13-09-2016 THL1_RS14095 6d6298288dad02be43c142b0d088b4ca 458 PANTHER PTHR30182 1 455 4.6E-246 T 13-09-2016 THL1_RS25795 b9767f879ee52ca3f3b7681e5cb0ee2f 76 ProSitePatterns PS00057 Ribosomal protein S18 signature. 21 44 - T 13-09-2016 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS25795 b9767f879ee52ca3f3b7681e5cb0ee2f 76 SUPERFAMILY SSF46911 3 74 1.57E-28 T 13-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS25795 b9767f879ee52ca3f3b7681e5cb0ee2f 76 TIGRFAM TIGR00165 S18: ribosomal protein bS18 4 72 1.6E-36 T 13-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS25795 b9767f879ee52ca3f3b7681e5cb0ee2f 76 Gene3D G3DSA:4.10.640.10 8 74 5.3E-32 T 13-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS25795 b9767f879ee52ca3f3b7681e5cb0ee2f 76 Pfam PF01084 Ribosomal protein S18 18 68 2.5E-24 T 13-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS25795 b9767f879ee52ca3f3b7681e5cb0ee2f 76 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 21 71 3.0E-22 T 13-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS25795 b9767f879ee52ca3f3b7681e5cb0ee2f 76 PANTHER PTHR13479 2 76 1.1E-30 T 13-09-2016 THL1_RS25795 b9767f879ee52ca3f3b7681e5cb0ee2f 76 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 2 73 20.482 T 13-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS25795 b9767f879ee52ca3f3b7681e5cb0ee2f 76 PRINTS PR00974 Ribosomal protein S18 family signature 28 38 2.9E-18 T 13-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS25795 b9767f879ee52ca3f3b7681e5cb0ee2f 76 PRINTS PR00974 Ribosomal protein S18 family signature 60 70 2.9E-18 T 13-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS25795 b9767f879ee52ca3f3b7681e5cb0ee2f 76 PRINTS PR00974 Ribosomal protein S18 family signature 38 45 2.9E-18 T 13-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS25795 b9767f879ee52ca3f3b7681e5cb0ee2f 76 PRINTS PR00974 Ribosomal protein S18 family signature 46 60 2.9E-18 T 13-09-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS11960 f7ed8962ade4471d71b73a88107ad5f8 447 Gene3D G3DSA:3.40.50.720 235 441 4.5E-71 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11960 f7ed8962ade4471d71b73a88107ad5f8 447 PANTHER PTHR11374 1 444 2.9E-242 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS11960 f7ed8962ade4471d71b73a88107ad5f8 447 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 420 5.0E-139 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS11960 f7ed8962ade4471d71b73a88107ad5f8 447 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 204 296 8.2E-38 T 13-09-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 THL1_RS11960 f7ed8962ade4471d71b73a88107ad5f8 447 SUPERFAMILY SSF51735 1 195 3.61E-55 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11960 f7ed8962ade4471d71b73a88107ad5f8 447 SMART SM00984 320 424 1.3E-46 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS11960 f7ed8962ade4471d71b73a88107ad5f8 447 Gene3D G3DSA:3.40.50.720 1 207 5.3E-75 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11960 f7ed8962ade4471d71b73a88107ad5f8 447 PIRSF PIRSF000124 1 439 4.7E-148 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS11960 f7ed8962ade4471d71b73a88107ad5f8 447 PANTHER PTHR11374:SF18 1 444 2.9E-242 T 13-09-2016 THL1_RS11960 f7ed8962ade4471d71b73a88107ad5f8 447 SUPERFAMILY SSF52413 309 435 2.22E-35 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS11960 f7ed8962ade4471d71b73a88107ad5f8 447 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 182 3.4E-65 T 13-09-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS11960 f7ed8962ade4471d71b73a88107ad5f8 447 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 423 4.2E-27 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS11960 f7ed8962ade4471d71b73a88107ad5f8 447 Gene3D G3DSA:1.20.5.100 208 233 2.6E-18 T 13-09-2016 THL1_RS11960 f7ed8962ade4471d71b73a88107ad5f8 447 SUPERFAMILY SSF48179 204 302 2.04E-32 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS11960 f7ed8962ade4471d71b73a88107ad5f8 447 PIRSF PIRSF500134 1 442 8.7E-184 T 13-09-2016 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|UniPathway: UPA00038 THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 PANTHER PTHR10815 160 351 2.0E-118 T 13-09-2016 THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 Gene3D G3DSA:1.10.10.10 271 352 6.0E-34 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 SMART SM00342 102 184 1.1E-17 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 273 351 1.2E-32 T 13-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 Gene3D G3DSA:1.10.10.60 140 183 3.2E-5 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 SUPERFAMILY SSF46689 89 135 3.94E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 PIRSF PIRSF000409 1 354 5.3E-141 T 13-09-2016 IPR016221 Bifunctional regulatory protein Ada THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 SUPERFAMILY SSF53155 192 270 4.71E-21 T 13-09-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 Gene3D G3DSA:3.40.10.10 8 88 6.9E-30 T 13-09-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 Gene3D G3DSA:3.30.160.70 184 270 3.7E-33 T 13-09-2016 THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 272 351 3.4E-35 T 13-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 SUPERFAMILY SSF46767 271 351 5.62E-31 T 13-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 Pfam PF02805 Metal binding domain of Ada 14 74 1.0E-29 T 13-09-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 SUPERFAMILY SSF57884 8 94 2.88E-28 T 13-09-2016 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 Pfam PF12833 Helix-turn-helix domain 108 185 8.6E-22 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 PANTHER PTHR10815:SF9 160 351 2.0E-118 T 13-09-2016 THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 Gene3D G3DSA:1.10.10.60 89 139 2.7E-20 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19030 afb5c50c1ad7cc256e177027d690206d 354 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 322 328 - T 13-09-2016 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 THL1_RS09805 e0a0fe7cb4f898a1a5158940f0fc21fc 437 SMART SM00984 331 429 1.6E-33 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS09805 e0a0fe7cb4f898a1a5158940f0fc21fc 437 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 19 193 2.2E-46 T 13-09-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS09805 e0a0fe7cb4f898a1a5158940f0fc21fc 437 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 19 424 3.0E-129 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS09805 e0a0fe7cb4f898a1a5158940f0fc21fc 437 SUPERFAMILY SSF52413 318 427 1.06E-28 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS09805 e0a0fe7cb4f898a1a5158940f0fc21fc 437 SUPERFAMILY SSF51735 19 207 3.0E-42 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS09805 e0a0fe7cb4f898a1a5158940f0fc21fc 437 SUPERFAMILY SSF48179 213 306 8.16E-30 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS09805 e0a0fe7cb4f898a1a5158940f0fc21fc 437 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 214 304 1.2E-27 T 13-09-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 THL1_RS09805 e0a0fe7cb4f898a1a5158940f0fc21fc 437 Gene3D G3DSA:3.40.50.720 244 428 5.6E-48 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS09805 e0a0fe7cb4f898a1a5158940f0fc21fc 437 PIRSF PIRSF000124 18 434 2.4E-59 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS09805 e0a0fe7cb4f898a1a5158940f0fc21fc 437 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 331 425 5.5E-23 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS09805 e0a0fe7cb4f898a1a5158940f0fc21fc 437 PIRSF PIRSF500136 8 436 3.0E-140 T 13-09-2016 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 THL1_RS09805 e0a0fe7cb4f898a1a5158940f0fc21fc 437 PANTHER PTHR11374 14 425 2.0E-180 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS09805 e0a0fe7cb4f898a1a5158940f0fc21fc 437 PANTHER PTHR11374:SF4 14 425 2.0E-180 T 13-09-2016 THL1_RS09805 e0a0fe7cb4f898a1a5158940f0fc21fc 437 Gene3D G3DSA:3.40.50.720 12 234 9.0E-49 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS15640 840b5ef13f306cea4dc481611a917b0c 476 SUPERFAMILY SSF102114 101 422 1.57E-45 T 13-09-2016 THL1_RS15640 840b5ef13f306cea4dc481611a917b0c 476 PANTHER PTHR11228:SF21 101 451 4.0E-38 T 13-09-2016 THL1_RS15640 840b5ef13f306cea4dc481611a917b0c 476 PANTHER PTHR11228 101 451 4.0E-38 T 13-09-2016 THL1_RS15640 840b5ef13f306cea4dc481611a917b0c 476 Pfam PF13353 4Fe-4S single cluster domain 110 225 7.1E-14 T 13-09-2016 THL1_RS15640 840b5ef13f306cea4dc481611a917b0c 476 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 108 119 - T 13-09-2016 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 THL1_RS15640 840b5ef13f306cea4dc481611a917b0c 476 TIGRFAM TIGR03906 quino_hemo_SAM: quinohemoprotein amine dehydrogenase maturation protein 10 475 2.1E-240 T 13-09-2016 IPR023886 Quinohemoprotein amine dehydrogenase, gamma subunit maturation protein THL1_RS15640 840b5ef13f306cea4dc481611a917b0c 476 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 353 441 2.8E-14 T 13-09-2016 IPR023885 4Fe4S-binding SPASM domain THL1_RS15640 840b5ef13f306cea4dc481611a917b0c 476 Gene3D G3DSA:3.20.20.70 98 431 1.0E-43 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS15640 840b5ef13f306cea4dc481611a917b0c 476 Pfam PF04055 Radical SAM superfamily 108 272 1.2E-12 T 13-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 THL1_RS27940 9618cfb6427416db7de713c273253f27 691 PANTHER PTHR24031 624 669 3.8E-127 T 13-09-2016 THL1_RS27940 9618cfb6427416db7de713c273253f27 691 PANTHER PTHR24031:SF249 268 282 3.8E-127 T 13-09-2016 THL1_RS27940 9618cfb6427416db7de713c273253f27 691 Pfam PF00270 DEAD/DEAH box helicase 293 430 2.5E-17 T 13-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THL1_RS27940 9618cfb6427416db7de713c273253f27 691 SMART SM00490 507 587 4.6E-21 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS27940 9618cfb6427416db7de713c273253f27 691 SUPERFAMILY SSF50249 6 171 3.94E-36 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS27940 9618cfb6427416db7de713c273253f27 691 PANTHER PTHR24031 299 601 3.8E-127 T 13-09-2016 THL1_RS27940 9618cfb6427416db7de713c273253f27 691 PANTHER PTHR24031 268 282 3.8E-127 T 13-09-2016 THL1_RS27940 9618cfb6427416db7de713c273253f27 691 SUPERFAMILY SSF52540 506 651 3.29E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27940 9618cfb6427416db7de713c273253f27 691 SUPERFAMILY SSF52540 292 342 3.29E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27940 9618cfb6427416db7de713c273253f27 691 SUPERFAMILY SSF52540 179 452 1.56E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27940 9618cfb6427416db7de713c273253f27 691 Gene3D G3DSA:3.40.50.300 453 636 1.5E-42 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27940 9618cfb6427416db7de713c273253f27 691 Gene3D G3DSA:3.40.50.300 255 452 8.7E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27940 9618cfb6427416db7de713c273253f27 691 Pfam PF17191 RecG wedge domain 11 164 1.4E-15 T 13-09-2016 IPR033454 RecG, wedge domain THL1_RS27940 9618cfb6427416db7de713c273253f27 691 PANTHER PTHR24031:SF249 299 601 3.8E-127 T 13-09-2016 THL1_RS27940 9618cfb6427416db7de713c273253f27 691 PANTHER PTHR24031:SF249 624 669 3.8E-127 T 13-09-2016 THL1_RS27940 9618cfb6427416db7de713c273253f27 691 Gene3D G3DSA:1.10.150.20 4 35 1.1E-4 T 13-09-2016 THL1_RS27940 9618cfb6427416db7de713c273253f27 691 Gene3D G3DSA:2.40.50.140 45 138 8.5E-21 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS27940 9618cfb6427416db7de713c273253f27 691 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 27 663 1.5E-225 T 13-09-2016 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 THL1_RS27940 9618cfb6427416db7de713c273253f27 691 SMART SM00487 265 458 4.3E-27 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS27940 9618cfb6427416db7de713c273253f27 691 Pfam PF00271 Helicase conserved C-terminal domain 478 586 3.5E-18 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS21355 e345ef3db8d0438b539c9ac35e98eb6d 278 Pfam PF08668 HDOD domain 23 202 1.9E-46 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS21355 e345ef3db8d0438b539c9ac35e98eb6d 278 SUPERFAMILY SSF109604 12 266 3.87E-58 T 13-09-2016 THL1_RS21355 e345ef3db8d0438b539c9ac35e98eb6d 278 PANTHER PTHR33525:SF2 4 278 6.3E-122 T 13-09-2016 THL1_RS21355 e345ef3db8d0438b539c9ac35e98eb6d 278 Gene3D G3DSA:1.10.3150.10 5 267 4.3E-64 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS21355 e345ef3db8d0438b539c9ac35e98eb6d 278 PANTHER PTHR33525 4 278 6.3E-122 T 13-09-2016 THL1_RS14705 49bcec5fced02f3568df46bc8cc9c66f 325 SUPERFAMILY SSF46785 23 102 3.29E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14705 49bcec5fced02f3568df46bc8cc9c66f 325 Pfam PF03466 LysR substrate binding domain 111 317 2.2E-30 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS14705 49bcec5fced02f3568df46bc8cc9c66f 325 Gene3D G3DSA:1.10.10.10 25 110 3.5E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14705 49bcec5fced02f3568df46bc8cc9c66f 325 Gene3D G3DSA:3.40.190.10 112 205 4.4E-15 T 13-09-2016 THL1_RS14705 49bcec5fced02f3568df46bc8cc9c66f 325 PANTHER PTHR30126 25 316 1.9E-53 T 13-09-2016 THL1_RS14705 49bcec5fced02f3568df46bc8cc9c66f 325 Gene3D G3DSA:3.40.190.10 206 284 3.9E-14 T 13-09-2016 THL1_RS14705 49bcec5fced02f3568df46bc8cc9c66f 325 SUPERFAMILY SSF53850 111 320 2.41E-33 T 13-09-2016 THL1_RS14705 49bcec5fced02f3568df46bc8cc9c66f 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 53 63 1.3E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14705 49bcec5fced02f3568df46bc8cc9c66f 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.3E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14705 49bcec5fced02f3568df46bc8cc9c66f 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 63 74 1.3E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14705 49bcec5fced02f3568df46bc8cc9c66f 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 27 86 4.3E-19 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS25595 5dedea2a35b71f8339879a25a528d165 88 TIGRFAM TIGR02419 C4_traR_proteo: phage/conjugal plasmid C-4 type zinc finger protein, TraR family 12 66 3.2E-17 T 13-09-2016 IPR012783 Zinc finger, C4 DksA/TraR-type THL1_RS25595 5dedea2a35b71f8339879a25a528d165 88 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 39 63 - T 13-09-2016 IPR020458 Zinc finger, DksA/TraR C4-type conserved site THL1_RS25595 5dedea2a35b71f8339879a25a528d165 88 PANTHER PTHR38777 2 88 6.5E-33 T 13-09-2016 THL1_RS25595 5dedea2a35b71f8339879a25a528d165 88 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 39 69 7.6E-13 T 13-09-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 THL1_RS25595 5dedea2a35b71f8339879a25a528d165 88 PRINTS PR00618 DksA/TraR zinc finger signature 51 63 5.9E-5 T 13-09-2016 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria THL1_RS25595 5dedea2a35b71f8339879a25a528d165 88 PRINTS PR00618 DksA/TraR zinc finger signature 39 50 5.9E-5 T 13-09-2016 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria THL1_RS25595 5dedea2a35b71f8339879a25a528d165 88 SUPERFAMILY SSF57716 38 74 3.42E-8 T 13-09-2016 THL1_RS25595 5dedea2a35b71f8339879a25a528d165 88 PANTHER PTHR38777:SF1 2 88 6.5E-33 T 13-09-2016 THL1_RS07850 34858306f6555e05bef78844deb249ae 343 PANTHER PTHR33442 1 333 1.1E-120 T 13-09-2016 THL1_RS07850 34858306f6555e05bef78844deb249ae 343 Gene3D G3DSA:3.10.310.10 156 318 9.2E-55 T 13-09-2016 THL1_RS07850 34858306f6555e05bef78844deb249ae 343 Gene3D G3DSA:3.10.310.10 1 155 4.3E-61 T 13-09-2016 THL1_RS07850 34858306f6555e05bef78844deb249ae 343 Pfam PF05544 Proline racemase 10 330 6.0E-120 T 13-09-2016 IPR008794 Proline racemase family THL1_RS07850 34858306f6555e05bef78844deb249ae 343 PANTHER PTHR33442:SF2 1 333 1.1E-120 T 13-09-2016 THL1_RS07850 34858306f6555e05bef78844deb249ae 343 PIRSF PIRSF029792 1 333 9.4E-121 T 13-09-2016 IPR008794 Proline racemase family THL1_RS07850 34858306f6555e05bef78844deb249ae 343 SUPERFAMILY SSF54506 1 330 6.48E-103 T 13-09-2016 THL1_RS03850 6f2caa4490ee8c68927e363ac3411c88 220 Pfam PF00677 Lumazine binding domain 3 87 9.7E-21 T 13-09-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS03850 6f2caa4490ee8c68927e363ac3411c88 220 Pfam PF00677 Lumazine binding domain 100 184 2.1E-20 T 13-09-2016 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS03850 6f2caa4490ee8c68927e363ac3411c88 220 Gene3D G3DSA:2.40.30.20 105 194 2.7E-31 T 13-09-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS03850 6f2caa4490ee8c68927e363ac3411c88 220 Gene3D G3DSA:2.40.30.20 5 104 8.7E-30 T 13-09-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS03850 6f2caa4490ee8c68927e363ac3411c88 220 PANTHER PTHR21098 1 219 5.4E-102 T 13-09-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS03850 6f2caa4490ee8c68927e363ac3411c88 220 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 198 1.7E-64 T 13-09-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS03850 6f2caa4490ee8c68927e363ac3411c88 220 SUPERFAMILY SSF63380 1 88 3.32E-25 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS03850 6f2caa4490ee8c68927e363ac3411c88 220 PIRSF PIRSF000498 1 212 7.1E-75 T 13-09-2016 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS03850 6f2caa4490ee8c68927e363ac3411c88 220 SUPERFAMILY SSF63380 93 194 1.96E-31 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS15475 1b425664f6c56d4f018fa24f028beb54 165 PANTHER PTHR10681 3 165 9.4E-50 T 13-09-2016 THL1_RS15475 1b425664f6c56d4f018fa24f028beb54 165 PANTHER PTHR10681:SF81 3 165 9.4E-50 T 13-09-2016 THL1_RS15475 1b425664f6c56d4f018fa24f028beb54 165 Hamap MF_00269 Probable thiol peroxidase [tpx]. 3 165 37.154 T 13-09-2016 IPR002065 Putative thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 THL1_RS15475 1b425664f6c56d4f018fa24f028beb54 165 SUPERFAMILY SSF52833 1 163 1.01E-42 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS15475 1b425664f6c56d4f018fa24f028beb54 165 Gene3D G3DSA:3.40.30.10 2 165 4.2E-44 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS15475 1b425664f6c56d4f018fa24f028beb54 165 Pfam PF08534 Redoxin 19 162 3.5E-28 T 13-09-2016 IPR013740 Redoxin GO:0016491 THL1_RS15475 1b425664f6c56d4f018fa24f028beb54 165 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 13-09-2016 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 THL1_RS04160 79c864a087357a5f81fd834a4750d39b 213 Gene3D G3DSA:3.40.50.720 3 211 3.6E-50 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS04160 79c864a087357a5f81fd834a4750d39b 213 PANTHER PTHR14097:SF7 1 213 2.9E-68 T 13-09-2016 THL1_RS04160 79c864a087357a5f81fd834a4750d39b 213 SUPERFAMILY SSF51735 5 198 2.61E-44 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS04160 79c864a087357a5f81fd834a4750d39b 213 PANTHER PTHR14097 1 213 2.9E-68 T 13-09-2016 THL1_RS04160 79c864a087357a5f81fd834a4750d39b 213 Pfam PF13460 NAD(P)H-binding 12 153 2.9E-8 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS14770 a129abca7aaf20a89e1895ee664abd8c 159 PANTHER PTHR30154 3 140 3.5E-40 T 13-09-2016 THL1_RS14770 a129abca7aaf20a89e1895ee664abd8c 159 SMART SM00344 11 121 7.5E-32 T 13-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 THL1_RS14770 a129abca7aaf20a89e1895ee664abd8c 159 Gene3D G3DSA:1.10.10.10 9 62 8.3E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14770 a129abca7aaf20a89e1895ee664abd8c 159 PANTHER PTHR30154:SF28 3 140 3.5E-40 T 13-09-2016 THL1_RS14770 a129abca7aaf20a89e1895ee664abd8c 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 27 38 2.6E-14 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS14770 a129abca7aaf20a89e1895ee664abd8c 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 57 2.6E-14 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS14770 a129abca7aaf20a89e1895ee664abd8c 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 11 27 2.6E-14 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS14770 a129abca7aaf20a89e1895ee664abd8c 159 SUPERFAMILY SSF46785 10 69 5.94E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14770 a129abca7aaf20a89e1895ee664abd8c 159 SUPERFAMILY SSF54909 74 141 8.98E-12 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS14770 a129abca7aaf20a89e1895ee664abd8c 159 Pfam PF13412 Winged helix-turn-helix DNA-binding 11 58 3.1E-16 T 13-09-2016 THL1_RS14770 a129abca7aaf20a89e1895ee664abd8c 159 Gene3D G3DSA:3.30.70.920 64 138 1.4E-16 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS14770 a129abca7aaf20a89e1895ee664abd8c 159 Pfam PF01037 Lrp/AsnC ligand binding domain 77 134 3.8E-13 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS22445 b4192a7008d09080da246ab14a83d7c8 137 Pfam PF13652 Putative quorum-sensing-regulated virulence factor 20 130 2.6E-62 T 13-09-2016 IPR025203 Putative quorum-sensing-regulated virulence factor, QSregVF THL1_RS19070 1f4e21970067480bf1194bf1d6344c7c 460 Pfam PF00202 Aminotransferase class-III 38 447 3.9E-90 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS19070 1f4e21970067480bf1194bf1d6344c7c 460 SUPERFAMILY SSF53383 12 451 3.73E-113 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS19070 1f4e21970067480bf1194bf1d6344c7c 460 Gene3D G3DSA:3.90.1150.10 348 454 6.1E-39 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS19070 1f4e21970067480bf1194bf1d6344c7c 460 Gene3D G3DSA:3.90.1150.10 11 72 6.1E-39 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS19070 1f4e21970067480bf1194bf1d6344c7c 460 Gene3D G3DSA:3.40.640.10 75 346 1.7E-75 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS19070 1f4e21970067480bf1194bf1d6344c7c 460 PANTHER PTHR11986:SF81 8 458 6.7E-130 T 13-09-2016 THL1_RS19070 1f4e21970067480bf1194bf1d6344c7c 460 PANTHER PTHR11986 8 458 6.7E-130 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS17535 e6a2e997fb6c8500ecfadb7f9c53b260 504 PANTHER PTHR35004 1 449 3.5E-118 T 13-09-2016 THL1_RS17535 e6a2e997fb6c8500ecfadb7f9c53b260 504 PANTHER PTHR35004:SF2 1 449 3.5E-118 T 13-09-2016 THL1_RS17535 e6a2e997fb6c8500ecfadb7f9c53b260 504 Gene3D G3DSA:3.30.420.10 159 294 1.1E-8 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS17535 e6a2e997fb6c8500ecfadb7f9c53b260 504 SUPERFAMILY SSF53098 156 294 2.31E-7 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS17535 e6a2e997fb6c8500ecfadb7f9c53b260 504 Pfam PF00665 Integrase core domain 129 259 5.6E-18 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 PANTHER PTHR11482 14 410 7.8E-138 T 13-09-2016 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 44 62 - T 13-09-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Reactome: REACT_13 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 Gene3D G3DSA:3.20.20.10 34 254 4.8E-61 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 7 411 37.728 T 13-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 Gene3D G3DSA:2.40.37.10 255 410 2.7E-51 T 13-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 PANTHER PTHR11482:SF5 14 410 7.8E-138 T 13-09-2016 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 258 277 3.3E-19 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 368 381 3.3E-19 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 175 188 3.3E-19 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 64 76 3.3E-19 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 44 62 3.3E-19 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 7 410 1.6E-122 T 13-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 SUPERFAMILY SSF50621 252 410 1.51E-51 T 13-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 PRINTS PR01181 Diaminopimelate decarboxylase signature 286 304 2.5E-26 T 13-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 PRINTS PR01181 Diaminopimelate decarboxylase signature 150 159 2.5E-26 T 13-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 PRINTS PR01181 Diaminopimelate decarboxylase signature 378 400 2.5E-26 T 13-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 PRINTS PR01181 Diaminopimelate decarboxylase signature 62 79 2.5E-26 T 13-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 28 268 6.9E-52 T 13-09-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 SUPERFAMILY SSF51419 18 270 1.31E-57 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 273 387 7.8E-15 T 13-09-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS06570 76d2dfac833f278b71167e615d9ff1d9 411 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 209 222 - T 13-09-2016 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Reactome: REACT_13 THL1_RS09140 b645103fe319fa4d399cb3c97b5306a8 149 PANTHER PTHR37421:SF1 2 147 6.1E-65 T 13-09-2016 THL1_RS09140 b645103fe319fa4d399cb3c97b5306a8 149 PANTHER PTHR37421 2 147 6.1E-65 T 13-09-2016 THL1_RS09140 b645103fe319fa4d399cb3c97b5306a8 149 Hamap MF_00676 UPF0260 protein YcgN [ycgN]. 4 149 41.91 T 13-09-2016 IPR008228 Uncharacterised conserved protein UCP006173 THL1_RS09140 b645103fe319fa4d399cb3c97b5306a8 149 PIRSF PIRSF006173 1 149 2.5E-66 T 13-09-2016 IPR008228 Uncharacterised conserved protein UCP006173 THL1_RS09140 b645103fe319fa4d399cb3c97b5306a8 149 Pfam PF03692 Putative zinc- or iron-chelating domain 26 93 8.9E-8 T 13-09-2016 IPR005358 Putative zinc- or iron-chelating domain containing protein THL1_RS26975 33730bc63d088204dfe17778e8ae8915 181 SUPERFAMILY SSF51182 2 178 4.63E-81 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS26975 33730bc63d088204dfe17778e8ae8915 181 Gene3D G3DSA:2.60.120.10 2 178 5.5E-86 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS26975 33730bc63d088204dfe17778e8ae8915 181 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 3 177 1.3E-86 T 13-09-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 THL1_RS26975 33730bc63d088204dfe17778e8ae8915 181 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 175 2.3E-78 T 13-09-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 THL1_RS26975 33730bc63d088204dfe17778e8ae8915 181 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 180 5.0E-71 T 13-09-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 THL1_RS26975 33730bc63d088204dfe17778e8ae8915 181 PANTHER PTHR21047 6 180 3.0E-80 T 13-09-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 THL1_RS26655 86cba8871ffb390fea9a0655eab8fcc7 484 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 4 371 5.4E-102 T 13-09-2016 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 UniPathway: UPA00060 THL1_RS26655 86cba8871ffb390fea9a0655eab8fcc7 484 SUPERFAMILY SSF143437 1 175 1.52E-47 T 13-09-2016 THL1_RS26655 86cba8871ffb390fea9a0655eab8fcc7 484 SUPERFAMILY SSF52821 395 482 7.33E-8 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS26655 86cba8871ffb390fea9a0655eab8fcc7 484 PANTHER PTHR14911:SF15 3 418 4.1E-232 T 13-09-2016 THL1_RS26655 86cba8871ffb390fea9a0655eab8fcc7 484 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 178 370 1.6E-61 T 13-09-2016 IPR020536 Thil, AANH domain GO:0004810 UniPathway: UPA00060 THL1_RS26655 86cba8871ffb390fea9a0655eab8fcc7 484 SUPERFAMILY SSF52402 181 374 5.51E-38 T 13-09-2016 THL1_RS26655 86cba8871ffb390fea9a0655eab8fcc7 484 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 484 203.726 T 13-09-2016 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 UniPathway: UPA00060 THL1_RS26655 86cba8871ffb390fea9a0655eab8fcc7 484 Gene3D G3DSA:3.40.250.10 392 481 2.0E-6 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS26655 86cba8871ffb390fea9a0655eab8fcc7 484 Gene3D G3DSA:3.40.50.620 175 335 1.4E-32 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS26655 86cba8871ffb390fea9a0655eab8fcc7 484 PANTHER PTHR14911 3 418 4.1E-232 T 13-09-2016 THL1_RS26655 86cba8871ffb390fea9a0655eab8fcc7 484 Pfam PF02926 THUMP domain 28 164 1.8E-18 T 13-09-2016 IPR004114 THUMP domain GO:0003723 THL1_RS26655 86cba8871ffb390fea9a0655eab8fcc7 484 TIGRFAM TIGR04271 ThiI_C_thiazole: thiazole biosynthesis domain 385 483 1.2E-35 T 13-09-2016 IPR026340 Thiazole biosynthesis domain GO:0052837 UniPathway: UPA00060 THL1_RS26655 86cba8871ffb390fea9a0655eab8fcc7 484 SMART SM00981 77 167 4.3E-22 T 13-09-2016 IPR004114 THUMP domain GO:0003723 THL1_RS01690 99d1d717a9fc3bb77c6abd6ca29ce41f 472 Pfam PF00155 Aminotransferase class I and II 108 459 7.0E-34 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS01690 99d1d717a9fc3bb77c6abd6ca29ce41f 472 SUPERFAMILY SSF53383 90 468 9.63E-94 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS01690 99d1d717a9fc3bb77c6abd6ca29ce41f 472 PANTHER PTHR11751:SF275 86 469 1.6E-195 T 13-09-2016 THL1_RS01690 99d1d717a9fc3bb77c6abd6ca29ce41f 472 SUPERFAMILY SSF46785 2 75 2.18E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS01690 99d1d717a9fc3bb77c6abd6ca29ce41f 472 Gene3D G3DSA:3.40.640.10 137 350 6.4E-67 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS01690 99d1d717a9fc3bb77c6abd6ca29ce41f 472 SMART SM00345 7 66 1.5E-20 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS01690 99d1d717a9fc3bb77c6abd6ca29ce41f 472 PANTHER PTHR11751 86 469 1.6E-195 T 13-09-2016 THL1_RS01690 99d1d717a9fc3bb77c6abd6ca29ce41f 472 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 3.7E-15 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS01690 99d1d717a9fc3bb77c6abd6ca29ce41f 472 Gene3D G3DSA:1.10.10.10 1 66 1.0E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS01690 99d1d717a9fc3bb77c6abd6ca29ce41f 472 Gene3D G3DSA:3.90.1150.10 351 462 1.2E-7 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS23890 df2f2cead087e974651ace57e40ad403 342 TIGRFAM TIGR00109 hemH: ferrochelatase 3 195 4.7E-40 T 13-09-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 THL1_RS23890 df2f2cead087e974651ace57e40ad403 342 Gene3D G3DSA:3.40.50.1400 190 338 6.1E-32 T 13-09-2016 THL1_RS23890 df2f2cead087e974651ace57e40ad403 342 SUPERFAMILY SSF53800 2 340 5.36E-83 T 13-09-2016 THL1_RS23890 df2f2cead087e974651ace57e40ad403 342 Pfam PF00762 Ferrochelatase 4 337 1.0E-96 T 13-09-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 THL1_RS23890 df2f2cead087e974651ace57e40ad403 342 PANTHER PTHR11108 226 334 5.0E-90 T 13-09-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 THL1_RS23890 df2f2cead087e974651ace57e40ad403 342 PANTHER PTHR11108 5 205 5.0E-90 T 13-09-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 THL1_RS23890 df2f2cead087e974651ace57e40ad403 342 Gene3D G3DSA:3.40.50.1400 4 189 8.0E-48 T 13-09-2016 THL1_RS23890 df2f2cead087e974651ace57e40ad403 342 Hamap MF_00323 Ferrochelatase [hemH]. 2 339 34.106 T 13-09-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 THL1_RS27100 745a1f5163cf40f78b830d4857d6f6bd 645 Pfam PF00270 DEAD/DEAH box helicase 17 176 8.9E-16 T 13-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THL1_RS27100 745a1f5163cf40f78b830d4857d6f6bd 645 SMART SM00487 11 207 9.5E-27 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS27100 745a1f5163cf40f78b830d4857d6f6bd 645 PANTHER PTHR13710 5 341 2.0E-160 T 13-09-2016 THL1_RS27100 745a1f5163cf40f78b830d4857d6f6bd 645 PANTHER PTHR13710 510 558 2.0E-160 T 13-09-2016 THL1_RS27100 745a1f5163cf40f78b830d4857d6f6bd 645 Gene3D G3DSA:3.40.50.300 6 187 3.4E-50 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27100 745a1f5163cf40f78b830d4857d6f6bd 645 PANTHER PTHR13710:SF81 5 341 2.0E-160 T 13-09-2016 THL1_RS27100 745a1f5163cf40f78b830d4857d6f6bd 645 SUPERFAMILY SSF52540 56 339 2.28E-60 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27100 745a1f5163cf40f78b830d4857d6f6bd 645 Gene3D G3DSA:3.40.50.300 196 334 3.0E-41 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27100 745a1f5163cf40f78b830d4857d6f6bd 645 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 130 139 - T 13-09-2016 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site GO:0003676|GO:0005524|GO:0008026 THL1_RS27100 745a1f5163cf40f78b830d4857d6f6bd 645 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 6 344 8.0E-114 T 13-09-2016 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 THL1_RS27100 745a1f5163cf40f78b830d4857d6f6bd 645 Gene3D G3DSA:1.10.10.10 511 640 5.8E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS27100 745a1f5163cf40f78b830d4857d6f6bd 645 SMART SM00490 241 322 2.7E-29 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS27100 745a1f5163cf40f78b830d4857d6f6bd 645 PANTHER PTHR13710:SF81 510 558 2.0E-160 T 13-09-2016 THL1_RS27100 745a1f5163cf40f78b830d4857d6f6bd 645 Pfam PF00271 Helicase conserved C-terminal domain 214 322 1.7E-18 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS27100 745a1f5163cf40f78b830d4857d6f6bd 645 Pfam PF16124 RecQ zinc-binding 512 558 7.8E-8 T 13-09-2016 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 SUPERFAMILY SSF52374 4 140 1.48E-97 T 13-09-2016 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 SUPERFAMILY SSF52374 175 386 1.48E-97 T 13-09-2016 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 Pfam PF01588 Putative tRNA binding domain 581 674 2.2E-20 T 13-09-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 SUPERFAMILY SSF57770 141 175 9.29E-13 T 13-09-2016 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 SUPERFAMILY SSF50249 571 676 1.86E-25 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 Gene3D G3DSA:1.10.730.10 379 534 1.2E-39 T 13-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 Gene3D G3DSA:2.20.28.20 144 175 2.4E-19 T 13-09-2016 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 SUPERFAMILY SSF47323 389 547 2.24E-41 T 13-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 Hamap MF_00098 Methionine--tRNA ligase [metG]. 5 545 39.389 T 13-09-2016 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 7 535 1.2E-177 T 13-09-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 Gene3D G3DSA:3.40.50.620 182 378 4.2E-84 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 Gene3D G3DSA:3.40.50.620 5 143 4.2E-84 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 PANTHER PTHR11946:SF86 1 632 5.1E-238 T 13-09-2016 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 Gene3D G3DSA:2.40.50.140 569 677 1.0E-35 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 Pfam PF09334 tRNA synthetases class I (M) 7 395 2.7E-156 T 13-09-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 538 677 2.6E-39 T 13-09-2016 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 14 25 - T 13-09-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 9 22 1.7E-24 T 13-09-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 1.7E-24 T 13-09-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 250 261 1.7E-24 T 13-09-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 290 305 1.7E-24 T 13-09-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 41 55 1.7E-24 T 13-09-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 PRINTS PR01041 Methionyl-tRNA synthetase signature 383 394 1.7E-24 T 13-09-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 THL1_RS08100 977bf0307b68b3732a1fda99f512b5fc 677 PANTHER PTHR11946 1 632 5.1E-238 T 13-09-2016 THL1_RS05515 1122845b48c5b41be1d92f07f60a9c15 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 1.6E-26 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS05515 1122845b48c5b41be1d92f07f60a9c15 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 119 2.6E-38 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS05515 1122845b48c5b41be1d92f07f60a9c15 379 PANTHER PTHR10909 1 379 8.4E-246 T 13-09-2016 THL1_RS05515 1122845b48c5b41be1d92f07f60a9c15 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 3.5E-44 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS05515 1122845b48c5b41be1d92f07f60a9c15 379 Gene3D G3DSA:2.40.110.10 123 219 1.3E-40 T 13-09-2016 THL1_RS05515 1122845b48c5b41be1d92f07f60a9c15 379 PANTHER PTHR10909:SF190 1 379 8.4E-246 T 13-09-2016 THL1_RS05515 1122845b48c5b41be1d92f07f60a9c15 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS05515 1122845b48c5b41be1d92f07f60a9c15 379 Gene3D G3DSA:1.20.140.10 220 378 3.6E-59 T 13-09-2016 THL1_RS05515 1122845b48c5b41be1d92f07f60a9c15 379 SUPERFAMILY SSF47203 229 378 3.22E-49 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS05515 1122845b48c5b41be1d92f07f60a9c15 379 SUPERFAMILY SSF56645 5 242 3.27E-91 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS05515 1122845b48c5b41be1d92f07f60a9c15 379 Gene3D G3DSA:1.10.540.10 6 120 4.2E-39 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS05515 1122845b48c5b41be1d92f07f60a9c15 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS15915 10f42cab4f49fb40f592bcef68daea46 218 SUPERFAMILY SSF100950 4 216 1.36E-72 T 13-09-2016 THL1_RS15915 10f42cab4f49fb40f592bcef68daea46 218 SMART SM00882 6 202 2.2E-71 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS15915 10f42cab4f49fb40f592bcef68daea46 218 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 13-09-2016 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 THL1_RS15915 10f42cab4f49fb40f592bcef68daea46 218 PANTHER PTHR13707 2 218 6.0E-115 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS15915 10f42cab4f49fb40f592bcef68daea46 218 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 4 208 1.0E-98 T 13-09-2016 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 THL1_RS15915 10f42cab4f49fb40f592bcef68daea46 218 Gene3D G3DSA:3.40.810.20 4 213 1.0E-88 T 13-09-2016 THL1_RS15915 10f42cab4f49fb40f592bcef68daea46 218 Pfam PF01144 Coenzyme A transferase 6 201 7.1E-42 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS10885 4f7a2e820967c51e73542b4347b876fb 389 Hamap MF_00558 Succinyl-CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 42.55 T 13-09-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 THL1_RS10885 4f7a2e820967c51e73542b4347b876fb 389 PANTHER PTHR11815 1 389 2.0E-235 T 13-09-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 THL1_RS10885 4f7a2e820967c51e73542b4347b876fb 389 SUPERFAMILY SSF56059 1 237 1.96E-81 T 13-09-2016 THL1_RS10885 4f7a2e820967c51e73542b4347b876fb 389 Gene3D G3DSA:3.30.470.20 96 239 3.7E-57 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS10885 4f7a2e820967c51e73542b4347b876fb 389 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 1.2E-175 T 13-09-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 THL1_RS10885 4f7a2e820967c51e73542b4347b876fb 389 SUPERFAMILY SSF52210 240 384 6.54E-53 T 13-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 THL1_RS10885 4f7a2e820967c51e73542b4347b876fb 389 Gene3D G3DSA:3.40.50.261 241 383 1.9E-66 T 13-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 THL1_RS10885 4f7a2e820967c51e73542b4347b876fb 389 Gene3D G3DSA:3.30.1490.20 21 95 3.4E-35 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS10885 4f7a2e820967c51e73542b4347b876fb 389 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 13-09-2016 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 THL1_RS10885 4f7a2e820967c51e73542b4347b876fb 389 PIRSF PIRSF001554 1 388 1.7E-155 T 13-09-2016 IPR005809 Succinyl-CoA synthetase, beta subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: REACT_1046|UniPathway: UPA00223 THL1_RS10885 4f7a2e820967c51e73542b4347b876fb 389 Pfam PF00549 CoA-ligase 262 382 8.1E-25 T 13-09-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 THL1_RS10885 4f7a2e820967c51e73542b4347b876fb 389 Pfam PF08442 ATP-grasp domain 2 203 2.3E-82 T 13-09-2016 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 THL1_RS19000 3f2bd224fbaed1a158e47cbe7fdb0d7f 312 PANTHER PTHR30537 1 310 1.4E-106 T 13-09-2016 THL1_RS19000 3f2bd224fbaed1a158e47cbe7fdb0d7f 312 Gene3D G3DSA:3.40.190.10 176 263 1.8E-14 T 13-09-2016 THL1_RS19000 3f2bd224fbaed1a158e47cbe7fdb0d7f 312 SUPERFAMILY SSF46785 4 87 6.59E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19000 3f2bd224fbaed1a158e47cbe7fdb0d7f 312 PANTHER PTHR30537:SF5 1 310 1.4E-106 T 13-09-2016 THL1_RS19000 3f2bd224fbaed1a158e47cbe7fdb0d7f 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.3E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19000 3f2bd224fbaed1a158e47cbe7fdb0d7f 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.3E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19000 3f2bd224fbaed1a158e47cbe7fdb0d7f 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.3E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19000 3f2bd224fbaed1a158e47cbe7fdb0d7f 312 Gene3D G3DSA:1.10.10.10 3 87 1.8E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19000 3f2bd224fbaed1a158e47cbe7fdb0d7f 312 SUPERFAMILY SSF53850 89 298 1.16E-39 T 13-09-2016 THL1_RS19000 3f2bd224fbaed1a158e47cbe7fdb0d7f 312 Gene3D G3DSA:3.40.190.10 92 175 5.5E-18 T 13-09-2016 THL1_RS19000 3f2bd224fbaed1a158e47cbe7fdb0d7f 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 2.3E-19 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19000 3f2bd224fbaed1a158e47cbe7fdb0d7f 312 Pfam PF03466 LysR substrate binding domain 88 295 2.4E-39 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS17575 352027643ac1e4b7b1a7555319bee61b 338 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 87 5.7E-28 T 13-09-2016 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 THL1_RS17575 352027643ac1e4b7b1a7555319bee61b 338 Gene3D G3DSA:3.30.930.10 9 338 8.9E-135 T 13-09-2016 THL1_RS17575 352027643ac1e4b7b1a7555319bee61b 338 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 8 337 51.31 T 13-09-2016 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 THL1_RS17575 352027643ac1e4b7b1a7555319bee61b 338 PANTHER PTHR11538 90 338 2.4E-109 T 13-09-2016 THL1_RS17575 352027643ac1e4b7b1a7555319bee61b 338 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 38 337 1.0E-109 T 13-09-2016 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 THL1_RS17575 352027643ac1e4b7b1a7555319bee61b 338 SUPERFAMILY SSF55681 92 338 9.07E-82 T 13-09-2016 THL1_RS17575 352027643ac1e4b7b1a7555319bee61b 338 Pfam PF01409 tRNA synthetases class II core domain (F) 92 337 4.9E-109 T 13-09-2016 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 THL1_RS17575 352027643ac1e4b7b1a7555319bee61b 338 SUPERFAMILY SSF46589 13 99 6.8E-24 T 13-09-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 THL1_RS20135 069c22681ec518cb16a30049ac19d33e 388 PANTHER PTHR11911:SF90 194 381 3.1E-36 T 13-09-2016 THL1_RS20135 069c22681ec518cb16a30049ac19d33e 388 Pfam PF00571 CBS domain 243 294 2.4E-11 T 13-09-2016 IPR000644 CBS domain THL1_RS20135 069c22681ec518cb16a30049ac19d33e 388 Pfam PF00571 CBS domain 316 370 2.8E-14 T 13-09-2016 IPR000644 CBS domain THL1_RS20135 069c22681ec518cb16a30049ac19d33e 388 PANTHER PTHR11911 194 381 3.1E-36 T 13-09-2016 THL1_RS20135 069c22681ec518cb16a30049ac19d33e 388 SMART SM00116 323 371 2.0E-11 T 13-09-2016 IPR000644 CBS domain THL1_RS20135 069c22681ec518cb16a30049ac19d33e 388 SMART SM00116 249 297 5.3E-8 T 13-09-2016 IPR000644 CBS domain THL1_RS20135 069c22681ec518cb16a30049ac19d33e 388 SUPERFAMILY SSF54631 230 374 2.74E-36 T 13-09-2016 THL1_RS20135 069c22681ec518cb16a30049ac19d33e 388 Pfam PF04982 HPP family 55 174 5.1E-32 T 13-09-2016 IPR007065 HPP THL1_RS20135 069c22681ec518cb16a30049ac19d33e 388 Gene3D G3DSA:3.10.580.10 238 372 1.9E-32 T 13-09-2016 THL1_RS14020 54fa755a1460e384334dd6e70bf02f97 244 SUPERFAMILY SSF53639 1 215 6.08E-61 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS14020 54fa755a1460e384334dd6e70bf02f97 244 SMART SM01007 10 190 5.8E-59 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS14020 54fa755a1460e384334dd6e70bf02f97 244 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 190 2.3E-49 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS14020 54fa755a1460e384334dd6e70bf02f97 244 Gene3D G3DSA:3.40.225.10 4 216 5.2E-64 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS14020 54fa755a1460e384334dd6e70bf02f97 244 PANTHER PTHR10672 5 238 6.7E-96 T 13-09-2016 THL1_RS04105 a0bcf9a23534967551767797653ab570 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 294 305 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS04105 a0bcf9a23534967551767797653ab570 506 Gene3D G3DSA:3.40.309.10 270 469 1.4E-61 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS04105 a0bcf9a23534967551767797653ab570 506 Pfam PF00171 Aldehyde dehydrogenase family 32 493 3.7E-163 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS04105 a0bcf9a23534967551767797653ab570 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS04105 a0bcf9a23534967551767797653ab570 506 PANTHER PTHR11699 1 506 0.0 T 13-09-2016 THL1_RS04105 a0bcf9a23534967551767797653ab570 506 SUPERFAMILY SSF53720 13 497 1.7E-160 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS04105 a0bcf9a23534967551767797653ab570 506 PANTHER PTHR11699:SF97 1 506 0.0 T 13-09-2016 THL1_RS04105 a0bcf9a23534967551767797653ab570 506 Gene3D G3DSA:3.40.605.10 18 269 2.1E-92 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS14610 15399ae6b68f989c51c4b99f0f7f92c9 309 Pfam PF00892 EamA-like transporter family 156 289 8.1E-15 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS14610 15399ae6b68f989c51c4b99f0f7f92c9 309 Pfam PF00892 EamA-like transporter family 15 146 1.7E-14 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS14610 15399ae6b68f989c51c4b99f0f7f92c9 309 PANTHER PTHR22911 5 291 2.0E-34 T 13-09-2016 THL1_RS14610 15399ae6b68f989c51c4b99f0f7f92c9 309 SUPERFAMILY SSF103481 51 147 5.49E-12 T 13-09-2016 THL1_RS14610 15399ae6b68f989c51c4b99f0f7f92c9 309 SUPERFAMILY SSF103481 197 292 1.83E-9 T 13-09-2016 THL1_RS18275 1f6b34ef926b52bb0d05cbe0ddb91ee1 304 PIRSF PIRSF037167 1 300 2.3E-137 T 13-09-2016 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 THL1_RS18275 1f6b34ef926b52bb0d05cbe0ddb91ee1 304 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 197 203 - T 13-09-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THL1_RS18275 1f6b34ef926b52bb0d05cbe0ddb91ee1 304 Gene3D G3DSA:1.10.8.10 8 99 5.9E-13 T 13-09-2016 THL1_RS18275 1f6b34ef926b52bb0d05cbe0ddb91ee1 304 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 8 285 1.9E-82 T 13-09-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 THL1_RS18275 1f6b34ef926b52bb0d05cbe0ddb91ee1 304 PANTHER PTHR18895:SF66 1 290 8.5E-157 T 13-09-2016 THL1_RS18275 1f6b34ef926b52bb0d05cbe0ddb91ee1 304 Pfam PF05175 Methyltransferase small domain 121 208 4.3E-17 T 13-09-2016 IPR007848 Methyltransferase small domain GO:0008168 THL1_RS18275 1f6b34ef926b52bb0d05cbe0ddb91ee1 304 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 1 293 52.161 T 13-09-2016 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 THL1_RS18275 1f6b34ef926b52bb0d05cbe0ddb91ee1 304 Gene3D G3DSA:3.40.50.150 101 278 4.2E-51 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS18275 1f6b34ef926b52bb0d05cbe0ddb91ee1 304 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 6 287 4.2E-130 T 13-09-2016 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 THL1_RS18275 1f6b34ef926b52bb0d05cbe0ddb91ee1 304 PANTHER PTHR18895 1 290 8.5E-157 T 13-09-2016 THL1_RS18275 1f6b34ef926b52bb0d05cbe0ddb91ee1 304 SUPERFAMILY SSF53335 9 285 1.45E-54 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS17795 c08f02ca584ea1743a923f5e1abf497d 341 SUPERFAMILY SSF52096 89 199 9.73E-27 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS17795 c08f02ca584ea1743a923f5e1abf497d 341 SUPERFAMILY SSF52096 230 289 9.73E-27 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS17795 c08f02ca584ea1743a923f5e1abf497d 341 PANTHER PTHR33209:SF2 2 340 1.0E-184 T 13-09-2016 THL1_RS17795 c08f02ca584ea1743a923f5e1abf497d 341 Pfam PF08496 Peptidase family S49 N-terminal 2 148 2.4E-52 T 13-09-2016 IPR013703 Peptidase S49, N-terminal proteobacteria GO:0004252|GO:0005886 THL1_RS17795 c08f02ca584ea1743a923f5e1abf497d 341 PANTHER PTHR33209 2 340 1.0E-184 T 13-09-2016 THL1_RS17795 c08f02ca584ea1743a923f5e1abf497d 341 Gene3D G3DSA:3.90.226.10 87 195 1.6E-32 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS17795 c08f02ca584ea1743a923f5e1abf497d 341 Gene3D G3DSA:3.90.226.10 261 299 1.6E-32 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS17795 c08f02ca584ea1743a923f5e1abf497d 341 Pfam PF01343 Peptidase family S49 152 299 8.7E-44 T 13-09-2016 IPR002142 Peptidase S49 GO:0006508|GO:0008233 THL1_RS16960 1cbc280218976b469fc495aec1ca132a 434 Pfam PF03600 Citrate transporter 14 378 7.9E-48 T 13-09-2016 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 THL1_RS16960 1cbc280218976b469fc495aec1ca132a 434 PANTHER PTHR10283:SF87 7 433 1.8E-172 T 13-09-2016 IPR014738 Citrate transporter GO:0015137|GO:0015746 THL1_RS16960 1cbc280218976b469fc495aec1ca132a 434 PANTHER PTHR10283 7 433 1.8E-172 T 13-09-2016 THL1_RS16960 1cbc280218976b469fc495aec1ca132a 434 TIGRFAM TIGR00784 citMHS: citrate transporter 1 432 1.9E-200 T 13-09-2016 IPR014738 Citrate transporter GO:0015137|GO:0015746 THL1_RS00530 3ced009d2a2ce159df7f5cabd32699ac 839 SUPERFAMILY SSF46894 773 838 1.09E-19 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS00530 3ced009d2a2ce159df7f5cabd32699ac 839 SMART SM00421 775 832 2.6E-21 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS00530 3ced009d2a2ce159df7f5cabd32699ac 839 Gene3D G3DSA:1.25.40.10 419 757 7.9E-34 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS00530 3ced009d2a2ce159df7f5cabd32699ac 839 Pfam PF00196 Bacterial regulatory proteins, luxR family 777 832 6.8E-18 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS00530 3ced009d2a2ce159df7f5cabd32699ac 839 Gene3D G3DSA:1.10.10.10 772 837 4.7E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00530 3ced009d2a2ce159df7f5cabd32699ac 839 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 808 820 1.0E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS00530 3ced009d2a2ce159df7f5cabd32699ac 839 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 778 792 1.0E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS00530 3ced009d2a2ce159df7f5cabd32699ac 839 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 792 808 1.0E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS00530 3ced009d2a2ce159df7f5cabd32699ac 839 SUPERFAMILY SSF48452 450 621 3.8E-11 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS12600 ebffc772bf51a804afcc32069a7544a8 261 Gene3D G3DSA:3.40.810.20 3 245 3.6E-91 T 13-09-2016 THL1_RS12600 ebffc772bf51a804afcc32069a7544a8 261 PANTHER PTHR13707 1 238 5.2E-115 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS12600 ebffc772bf51a804afcc32069a7544a8 261 PANTHER PTHR13707:SF35 1 238 5.2E-115 T 13-09-2016 THL1_RS12600 ebffc772bf51a804afcc32069a7544a8 261 SMART SM00882 9 218 2.2E-39 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS12600 ebffc772bf51a804afcc32069a7544a8 261 SUPERFAMILY SSF100950 4 246 9.34E-72 T 13-09-2016 THL1_RS12600 ebffc772bf51a804afcc32069a7544a8 261 Pfam PF01144 Coenzyme A transferase 9 218 1.1E-48 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS00470 c7581a6ec3bbba92732063c46e9e97e8 301 Pfam PF03547 Membrane transport protein 160 295 9.2E-9 T 13-09-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 THL1_RS00470 c7581a6ec3bbba92732063c46e9e97e8 301 PANTHER PTHR31752:SF13 95 289 1.9E-47 T 13-09-2016 THL1_RS00470 c7581a6ec3bbba92732063c46e9e97e8 301 PANTHER PTHR31752 95 289 1.9E-47 T 13-09-2016 THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 320 4.7E-109 T 13-09-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 PANTHER PTHR11451:SF41 4 324 9.4E-107 T 13-09-2016 THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 SUPERFAMILY SSF48163 314 472 7.85E-36 T 13-09-2016 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 21 - T 13-09-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 PRINTS PR00987 Glutamyl-tRNA synthetase signature 36 49 1.3E-21 T 13-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 PRINTS PR00987 Glutamyl-tRNA synthetase signature 193 203 1.3E-21 T 13-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 PRINTS PR00987 Glutamyl-tRNA synthetase signature 21 32 1.3E-21 T 13-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 PRINTS PR00987 Glutamyl-tRNA synthetase signature 209 217 1.3E-21 T 13-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 PRINTS PR00987 Glutamyl-tRNA synthetase signature 7 19 1.3E-21 T 13-09-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 Gene3D G3DSA:1.10.1160.10 246 329 1.3E-32 T 13-09-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: REACT_71 THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 4 471 30.086 T 13-09-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 SUPERFAMILY SSF52374 4 308 4.56E-110 T 13-09-2016 THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 Gene3D G3DSA:3.40.50.620 195 244 5.2E-46 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 Gene3D G3DSA:3.40.50.620 3 68 5.2E-46 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 Gene3D G3DSA:3.90.800.10 69 194 3.4E-42 T 13-09-2016 THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 PANTHER PTHR11451 4 324 9.4E-107 T 13-09-2016 THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 3 471 1.1E-143 T 13-09-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 THL1_RS09935 beafdf1483cee25b5b80b7b1cf2bea54 493 Gene3D G3DSA:1.10.10.350 371 472 5.9E-14 T 13-09-2016 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 THL1_RS01045 ede2597e5822a3e9942d6d6ff9805682 513 TIGRFAM TIGR03173 pbuX: xanthine permease 27 437 2.1E-152 T 13-09-2016 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 THL1_RS01045 ede2597e5822a3e9942d6d6ff9805682 513 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 352 372 - T 13-09-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 THL1_RS01045 ede2597e5822a3e9942d6d6ff9805682 513 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 24 435 7.8E-104 T 13-09-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 THL1_RS01045 ede2597e5822a3e9942d6d6ff9805682 513 Pfam PF00860 Permease family 25 404 1.4E-90 T 13-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS01045 ede2597e5822a3e9942d6d6ff9805682 513 PANTHER PTHR11119 4 438 1.8E-109 T 13-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS01045 ede2597e5822a3e9942d6d6ff9805682 513 PANTHER PTHR11119:SF3 4 438 1.8E-109 T 13-09-2016 THL1_RS13580 cb043c96385453cc788e53c38753b074 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 261 7.4E-12 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS13580 cb043c96385453cc788e53c38753b074 268 PANTHER PTHR30222 21 267 1.3E-158 T 13-09-2016 THL1_RS13580 cb043c96385453cc788e53c38753b074 268 SUPERFAMILY SSF161098 20 266 4.58E-55 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS13580 cb043c96385453cc788e53c38753b074 268 Gene3D G3DSA:1.10.3720.10 23 267 2.4E-54 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS13580 cb043c96385453cc788e53c38753b074 268 PANTHER PTHR30222:SF7 21 267 1.3E-158 T 13-09-2016 THL1_RS22055 47d9b93cc99d212832920fada31bf940 83 Gene3D G3DSA:3.30.110.40 11 82 4.4E-27 T 13-09-2016 IPR001455 TusA-like domain THL1_RS22055 47d9b93cc99d212832920fada31bf940 83 PANTHER PTHR33279 1 82 3.7E-21 T 13-09-2016 THL1_RS22055 47d9b93cc99d212832920fada31bf940 83 SUPERFAMILY SSF64307 9 82 2.49E-23 T 13-09-2016 IPR001455 TusA-like domain THL1_RS22055 47d9b93cc99d212832920fada31bf940 83 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 15 39 - T 13-09-2016 IPR001455 TusA-like domain THL1_RS22055 47d9b93cc99d212832920fada31bf940 83 Pfam PF01206 Sulfurtransferase TusA 14 82 3.2E-22 T 13-09-2016 IPR001455 TusA-like domain THL1_RS25210 c26f38c7e20b31cef558c8251c08251f 155 Gene3D G3DSA:3.90.960.10 4 142 2.1E-20 T 13-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THL1_RS25210 c26f38c7e20b31cef558c8251c08251f 155 SUPERFAMILY SSF55826 5 145 4.06E-27 T 13-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THL1_RS25210 c26f38c7e20b31cef558c8251c08251f 155 Pfam PF04073 Aminoacyl-tRNA editing domain 23 141 1.7E-21 T 13-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 416 2.8E-19 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 397 2.8E-19 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 348 362 2.8E-19 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 376 2.8E-19 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 Gene3D G3DSA:1.10.287.130 172 202 9.6E-5 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 Gene3D G3DSA:1.10.287.130 238 266 9.6E-5 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 PANTHER PTHR24423:SF497 9 81 2.9E-90 T 13-09-2016 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 PANTHER PTHR24423:SF497 97 148 2.9E-90 T 13-09-2016 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 SMART SM00387 311 419 2.7E-31 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 Gene3D G3DSA:3.30.565.10 273 416 5.6E-42 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 PANTHER PTHR24423 97 148 2.9E-90 T 13-09-2016 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 315 418 1.1E-21 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 PANTHER PTHR24423:SF497 172 204 2.9E-90 T 13-09-2016 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 PANTHER PTHR24423 9 81 2.9E-90 T 13-09-2016 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 13 86 7.7E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 SUPERFAMILY SSF55785 11 85 1.29E-9 T 13-09-2016 IPR000014 PAS domain THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 Gene3D G3DSA:3.30.450.20 12 83 5.0E-10 T 13-09-2016 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 PANTHER PTHR24423:SF497 235 420 2.9E-90 T 13-09-2016 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 SUPERFAMILY SSF55874 262 417 4.19E-43 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 Pfam PF00512 His Kinase A (phospho-acceptor) domain 178 270 7.0E-8 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 Pfam PF08448 PAS fold 16 133 3.2E-5 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 SUPERFAMILY SSF47384 160 211 8.24E-6 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 SUPERFAMILY SSF47384 239 271 8.24E-6 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 PANTHER PTHR24423 172 204 2.9E-90 T 13-09-2016 THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 SMART SM00091 10 76 4.0E-4 T 13-09-2016 IPR000014 PAS domain THL1_RS03140 2c47e2f8e231cc051355157843e26238 427 PANTHER PTHR24423 235 420 2.9E-90 T 13-09-2016 THL1_RS27585 75743a8a640689e72d90da8dda74b2f1 130 PANTHER PTHR30204:SF1 1 115 3.3E-18 T 13-09-2016 THL1_RS27585 75743a8a640689e72d90da8dda74b2f1 130 Gene3D G3DSA:1.10.1660.10 2 57 1.1E-20 T 13-09-2016 THL1_RS27585 75743a8a640689e72d90da8dda74b2f1 130 ProSitePatterns PS00552 MerR-type HTH domain signature. 8 30 - T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS27585 75743a8a640689e72d90da8dda74b2f1 130 Pfam PF13411 MerR HTH family regulatory protein 6 70 3.8E-16 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS27585 75743a8a640689e72d90da8dda74b2f1 130 SUPERFAMILY SSF46955 5 118 2.12E-22 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS27585 75743a8a640689e72d90da8dda74b2f1 130 Gene3D G3DSA:1.10.1660.10 58 119 2.7E-12 T 13-09-2016 THL1_RS27585 75743a8a640689e72d90da8dda74b2f1 130 SMART SM00422 5 72 1.4E-18 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS27585 75743a8a640689e72d90da8dda74b2f1 130 PANTHER PTHR30204 1 115 3.3E-18 T 13-09-2016 THL1_RS16490 399e493e20cb83a417de6b2f6e1b76e1 223 SMART SM00895 85 207 1.1E-19 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS16490 399e493e20cb83a417de6b2f6e1b76e1 223 SUPERFAMILY SSF46785 8 79 1.32E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS16490 399e493e20cb83a417de6b2f6e1b76e1 223 SUPERFAMILY SSF48008 82 215 2.88E-26 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS16490 399e493e20cb83a417de6b2f6e1b76e1 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 75 5.6E-15 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS16490 399e493e20cb83a417de6b2f6e1b76e1 223 Pfam PF07729 FCD domain 85 206 4.9E-26 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS16490 399e493e20cb83a417de6b2f6e1b76e1 223 PANTHER PTHR11751 12 101 3.8E-32 T 13-09-2016 THL1_RS16490 399e493e20cb83a417de6b2f6e1b76e1 223 PANTHER PTHR11751:SF436 12 101 3.8E-32 T 13-09-2016 THL1_RS16490 399e493e20cb83a417de6b2f6e1b76e1 223 Gene3D G3DSA:1.10.10.10 7 76 2.8E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS16490 399e493e20cb83a417de6b2f6e1b76e1 223 SMART SM00345 17 75 2.3E-11 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS16490 399e493e20cb83a417de6b2f6e1b76e1 223 Gene3D G3DSA:1.20.120.530 79 218 3.4E-39 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS06565 53c99531a2733ee9582995822b38b1b5 308 Gene3D G3DSA:3.40.190.10 92 181 2.0E-16 T 13-09-2016 THL1_RS06565 53c99531a2733ee9582995822b38b1b5 308 PANTHER PTHR30427 1 299 1.9E-109 T 13-09-2016 THL1_RS06565 53c99531a2733ee9582995822b38b1b5 308 SUPERFAMILY SSF46785 3 82 6.53E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS06565 53c99531a2733ee9582995822b38b1b5 308 SUPERFAMILY SSF53850 92 296 1.1E-32 T 13-09-2016 THL1_RS06565 53c99531a2733ee9582995822b38b1b5 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 9.4E-19 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS06565 53c99531a2733ee9582995822b38b1b5 308 Gene3D G3DSA:3.40.190.10 182 262 1.6E-20 T 13-09-2016 THL1_RS06565 53c99531a2733ee9582995822b38b1b5 308 Pfam PF03466 LysR substrate binding domain 91 293 9.9E-33 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS06565 53c99531a2733ee9582995822b38b1b5 308 PANTHER PTHR30427:SF1 1 299 1.9E-109 T 13-09-2016 THL1_RS06565 53c99531a2733ee9582995822b38b1b5 308 Gene3D G3DSA:1.10.10.10 4 88 3.3E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS22855 9f0cb39ecadd5d6dbbf4c4250d84d193 295 SUPERFAMILY SSF53474 27 263 2.09E-38 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS22855 9f0cb39ecadd5d6dbbf4c4250d84d193 295 PANTHER PTHR12277 21 263 8.3E-45 T 13-09-2016 THL1_RS22855 9f0cb39ecadd5d6dbbf4c4250d84d193 295 Pfam PF12146 Serine aminopeptidase, S33 65 172 5.7E-15 T 13-09-2016 IPR022742 Serine aminopeptidase, S33 THL1_RS22855 9f0cb39ecadd5d6dbbf4c4250d84d193 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 109 2.4E-7 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS22855 9f0cb39ecadd5d6dbbf4c4250d84d193 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 155 168 2.4E-7 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS22855 9f0cb39ecadd5d6dbbf4c4250d84d193 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 141 154 2.4E-7 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS22855 9f0cb39ecadd5d6dbbf4c4250d84d193 295 Gene3D G3DSA:3.40.50.1820 37 248 2.2E-39 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS22855 9f0cb39ecadd5d6dbbf4c4250d84d193 295 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 141 155 2.2E-5 T 13-09-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 THL1_RS22855 9f0cb39ecadd5d6dbbf4c4250d84d193 295 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 70 78 2.2E-5 T 13-09-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 THL1_RS22855 9f0cb39ecadd5d6dbbf4c4250d84d193 295 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 97 108 2.2E-5 T 13-09-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 THL1_RS09115 ab0a8524d6065ed4ae5359d2af5a5ad5 353 PANTHER PTHR10426 4 353 8.9E-156 T 13-09-2016 IPR004141 Strictosidine synthase GO:0009058|GO:0016844 THL1_RS09115 ab0a8524d6065ed4ae5359d2af5a5ad5 353 PANTHER PTHR10426:SF4 4 353 8.9E-156 T 13-09-2016 THL1_RS09115 ab0a8524d6065ed4ae5359d2af5a5ad5 353 Gene3D G3DSA:2.120.10.30 10 349 9.8E-67 T 13-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like THL1_RS09115 ab0a8524d6065ed4ae5359d2af5a5ad5 353 Pfam PF03088 Strictosidine synthase 147 234 1.3E-29 T 13-09-2016 IPR018119 Strictosidine synthase, conserved region GO:0009058|GO:0016844 THL1_RS09115 ab0a8524d6065ed4ae5359d2af5a5ad5 353 SUPERFAMILY SSF63829 35 267 4.58E-57 T 13-09-2016 THL1_RS09115 ab0a8524d6065ed4ae5359d2af5a5ad5 353 SUPERFAMILY SSF63829 300 351 4.58E-57 T 13-09-2016 THL1_RS08935 87cd1560b745487d89f8bcd5ee01b5f5 332 SMART SM00342 245 328 8.7E-22 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS08935 87cd1560b745487d89f8bcd5ee01b5f5 332 Pfam PF12833 Helix-turn-helix domain 252 329 2.5E-19 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS08935 87cd1560b745487d89f8bcd5ee01b5f5 332 SUPERFAMILY SSF46689 281 330 1.66E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS08935 87cd1560b745487d89f8bcd5ee01b5f5 332 Gene3D G3DSA:1.10.10.60 281 330 7.8E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS08935 87cd1560b745487d89f8bcd5ee01b5f5 332 PANTHER PTHR11019 7 331 1.3E-81 T 13-09-2016 THL1_RS08935 87cd1560b745487d89f8bcd5ee01b5f5 332 PANTHER PTHR11019:SF52 7 331 1.3E-81 T 13-09-2016 THL1_RS08935 87cd1560b745487d89f8bcd5ee01b5f5 332 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 22 203 3.0E-48 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS08935 87cd1560b745487d89f8bcd5ee01b5f5 332 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 312 328 6.1E-7 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS08935 87cd1560b745487d89f8bcd5ee01b5f5 332 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 297 312 6.1E-7 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS05790 31b25d810f85683800cffb1e0c8be735 311 SUPERFAMILY SSF52833 3 88 8.7E-15 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS05790 31b25d810f85683800cffb1e0c8be735 311 Gene3D G3DSA:1.20.1050.10 121 216 5.9E-9 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS05790 31b25d810f85683800cffb1e0c8be735 311 PANTHER PTHR11260 153 217 1.2E-65 T 13-09-2016 THL1_RS05790 31b25d810f85683800cffb1e0c8be735 311 PANTHER PTHR11260 1 131 1.2E-65 T 13-09-2016 THL1_RS05790 31b25d810f85683800cffb1e0c8be735 311 Pfam PF13410 Glutathione S-transferase, C-terminal domain 151 214 1.4E-6 T 13-09-2016 THL1_RS05790 31b25d810f85683800cffb1e0c8be735 311 SUPERFAMILY SSF47616 140 217 1.42E-12 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS05790 31b25d810f85683800cffb1e0c8be735 311 Pfam PF13417 Glutathione S-transferase, N-terminal domain 6 78 5.3E-12 T 13-09-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THL1_RS05790 31b25d810f85683800cffb1e0c8be735 311 PANTHER PTHR11260:SF192 153 217 1.2E-65 T 13-09-2016 THL1_RS05790 31b25d810f85683800cffb1e0c8be735 311 PANTHER PTHR11260:SF192 1 131 1.2E-65 T 13-09-2016 THL1_RS05790 31b25d810f85683800cffb1e0c8be735 311 Gene3D G3DSA:3.40.30.10 2 99 3.5E-9 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS23555 c43463d477d0bc2353ab53483bf93e55 114 Gene3D G3DSA:2.60.120.10 17 112 4.1E-29 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS23555 c43463d477d0bc2353ab53483bf93e55 114 SUPERFAMILY SSF51182 16 112 4.65E-16 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS23555 c43463d477d0bc2353ab53483bf93e55 114 Pfam PF05899 Protein of unknown function (DUF861) 38 109 6.0E-24 T 13-09-2016 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 THL1_RS23555 c43463d477d0bc2353ab53483bf93e55 114 PANTHER PTHR33271 45 113 6.2E-19 T 13-09-2016 THL1_RS03210 54deb963901bc4d22b75e58e1cd3dcaf 491 Gene3D G3DSA:3.40.605.10 17 272 5.4E-78 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS03210 54deb963901bc4d22b75e58e1cd3dcaf 491 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS03210 54deb963901bc4d22b75e58e1cd3dcaf 491 PANTHER PTHR11699:SF203 1 491 3.3E-265 T 13-09-2016 THL1_RS03210 54deb963901bc4d22b75e58e1cd3dcaf 491 Gene3D G3DSA:3.40.309.10 273 456 3.6E-62 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS03210 54deb963901bc4d22b75e58e1cd3dcaf 491 PANTHER PTHR11699 1 491 3.3E-265 T 13-09-2016 THL1_RS03210 54deb963901bc4d22b75e58e1cd3dcaf 491 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 286 297 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS03210 54deb963901bc4d22b75e58e1cd3dcaf 491 Pfam PF00171 Aldehyde dehydrogenase family 20 477 3.8E-153 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS03210 54deb963901bc4d22b75e58e1cd3dcaf 491 SUPERFAMILY SSF53720 17 484 9.56E-148 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS13740 bddbff0d3f0af98c25440d95eb19b66e 176 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 41 170 9.6E-23 T 13-09-2016 IPR007387 Tripartite ATP-independent periplasmic transporter, DctQ component THL1_RS23980 c0482b7c3a25cbe6e1f287a1022144c3 424 PIRSF PIRSF000445 1 424 3.3E-156 T 13-09-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 THL1_RS23980 c0482b7c3a25cbe6e1f287a1022144c3 424 SUPERFAMILY SSF51735 160 313 1.28E-35 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23980 c0482b7c3a25cbe6e1f287a1022144c3 424 PANTHER PTHR21089 270 357 8.5E-138 T 13-09-2016 THL1_RS23980 c0482b7c3a25cbe6e1f287a1022144c3 424 PANTHER PTHR21089 1 254 8.5E-138 T 13-09-2016 THL1_RS23980 c0482b7c3a25cbe6e1f287a1022144c3 424 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 319 415 8.1E-23 T 13-09-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 THL1_RS23980 c0482b7c3a25cbe6e1f287a1022144c3 424 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 170 304 5.7E-49 T 13-09-2016 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase THL1_RS23980 c0482b7c3a25cbe6e1f287a1022144c3 424 SUPERFAMILY SSF69742 1 156 9.29E-49 T 13-09-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 THL1_RS23980 c0482b7c3a25cbe6e1f287a1022144c3 424 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 97 120 - T 13-09-2016 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 THL1_RS23980 c0482b7c3a25cbe6e1f287a1022144c3 424 Gene3D G3DSA:3.40.50.720 182 357 4.3E-38 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23980 c0482b7c3a25cbe6e1f287a1022144c3 424 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 416 30.819 T 13-09-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 THL1_RS23980 c0482b7c3a25cbe6e1f287a1022144c3 424 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 415 2.3E-141 T 13-09-2016 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 THL1_RS23980 c0482b7c3a25cbe6e1f287a1022144c3 424 PANTHER PTHR21089:SF3 270 357 8.5E-138 T 13-09-2016 THL1_RS23980 c0482b7c3a25cbe6e1f287a1022144c3 424 PANTHER PTHR21089:SF3 1 254 8.5E-138 T 13-09-2016 THL1_RS23980 c0482b7c3a25cbe6e1f287a1022144c3 424 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 154 2.4E-50 T 13-09-2016 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 THL1_RS23980 c0482b7c3a25cbe6e1f287a1022144c3 424 SUPERFAMILY SSF69075 315 416 1.31E-25 T 13-09-2016 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188|UniPathway: UPA00251 THL1_RS06765 a836da3c1883da97924f01e0476284ac 430 Hamap MF_00467 Probable M18 family aminopeptidase 2 [apeB]. 1 425 56.47 T 13-09-2016 IPR022984 M18 family aminopeptidase 2, putative GO:0004177 THL1_RS06765 a836da3c1883da97924f01e0476284ac 430 Pfam PF02127 Aminopeptidase I zinc metalloprotease (M18) 12 423 3.9E-137 T 13-09-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 THL1_RS06765 a836da3c1883da97924f01e0476284ac 430 PANTHER PTHR28570 1 425 4.3E-195 T 13-09-2016 THL1_RS06765 a836da3c1883da97924f01e0476284ac 430 Gene3D G3DSA:3.40.630.10 223 424 2.4E-118 T 13-09-2016 THL1_RS06765 a836da3c1883da97924f01e0476284ac 430 Gene3D G3DSA:3.40.630.10 4 86 2.4E-118 T 13-09-2016 THL1_RS06765 a836da3c1883da97924f01e0476284ac 430 SUPERFAMILY SSF53187 3 87 7.42E-106 T 13-09-2016 THL1_RS06765 a836da3c1883da97924f01e0476284ac 430 SUPERFAMILY SSF53187 214 424 7.42E-106 T 13-09-2016 THL1_RS06765 a836da3c1883da97924f01e0476284ac 430 Gene3D G3DSA:2.30.250.10 87 220 5.6E-46 T 13-09-2016 IPR023358 Peptidase M18, domain 2 GO:0004177 THL1_RS06765 a836da3c1883da97924f01e0476284ac 430 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 109 129 7.1E-43 T 13-09-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 THL1_RS06765 a836da3c1883da97924f01e0476284ac 430 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 144 161 7.1E-43 T 13-09-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 THL1_RS06765 a836da3c1883da97924f01e0476284ac 430 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 301 317 7.1E-43 T 13-09-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 THL1_RS06765 a836da3c1883da97924f01e0476284ac 430 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 76 92 7.1E-43 T 13-09-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 THL1_RS06765 a836da3c1883da97924f01e0476284ac 430 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 390 405 7.1E-43 T 13-09-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 THL1_RS06765 a836da3c1883da97924f01e0476284ac 430 PRINTS PR00932 Aminopeptidase I zinc metalloprotease (M18) signature 262 280 7.1E-43 T 13-09-2016 IPR001948 Peptidase M18 GO:0004177|GO:0006508|GO:0008270 THL1_RS06765 a836da3c1883da97924f01e0476284ac 430 SUPERFAMILY SSF101821 88 213 6.13E-33 T 13-09-2016 THL1_RS05130 b9c9af3894a2f7cd13efd72eeb4d7d96 676 SUPERFAMILY SSF58104 367 676 6.41E-76 T 13-09-2016 THL1_RS05130 b9c9af3894a2f7cd13efd72eeb4d7d96 676 Gene3D G3DSA:1.10.287.950 429 644 1.0E-55 T 13-09-2016 THL1_RS05130 b9c9af3894a2f7cd13efd72eeb4d7d96 676 SMART SM00304 347 399 3.1E-6 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS05130 b9c9af3894a2f7cd13efd72eeb4d7d96 676 SMART SM00304 402 452 16.0 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS05130 b9c9af3894a2f7cd13efd72eeb4d7d96 676 PANTHER PTHR32089:SF34 310 676 1.0E-133 T 13-09-2016 THL1_RS05130 b9c9af3894a2f7cd13efd72eeb4d7d96 676 PANTHER PTHR32089 310 676 1.0E-133 T 13-09-2016 THL1_RS05130 b9c9af3894a2f7cd13efd72eeb4d7d96 676 SMART SM00283 414 675 1.2E-77 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS05130 b9c9af3894a2f7cd13efd72eeb4d7d96 676 Pfam PF00672 HAMP domain 329 395 1.9E-8 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS05130 b9c9af3894a2f7cd13efd72eeb4d7d96 676 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 480 674 2.3E-48 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS00340 09bf3aab8f8596f3f432d29f5f40930e 304 Gene3D G3DSA:3.40.50.1980 181 301 1.4E-21 T 13-09-2016 THL1_RS00340 09bf3aab8f8596f3f432d29f5f40930e 304 PANTHER PTHR30477 4 278 1.8E-70 T 13-09-2016 THL1_RS00340 09bf3aab8f8596f3f432d29f5f40930e 304 SUPERFAMILY SSF53807 21 301 2.8E-72 T 13-09-2016 THL1_RS00340 09bf3aab8f8596f3f432d29f5f40930e 304 PRINTS PR00690 Adhesin family signature 64 81 8.6E-6 T 13-09-2016 IPR006128 Adhesion lipoprotein GO:0007155 THL1_RS00340 09bf3aab8f8596f3f432d29f5f40930e 304 PRINTS PR00690 Adhesin family signature 51 64 8.6E-6 T 13-09-2016 IPR006128 Adhesion lipoprotein GO:0007155 THL1_RS00340 09bf3aab8f8596f3f432d29f5f40930e 304 PRINTS PR00690 Adhesin family signature 190 211 8.6E-6 T 13-09-2016 IPR006128 Adhesion lipoprotein GO:0007155 THL1_RS00340 09bf3aab8f8596f3f432d29f5f40930e 304 PANTHER PTHR30477:SF1 4 278 1.8E-70 T 13-09-2016 THL1_RS00340 09bf3aab8f8596f3f432d29f5f40930e 304 Pfam PF01297 Zinc-uptake complex component A periplasmic 24 293 4.3E-56 T 13-09-2016 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 THL1_RS00340 09bf3aab8f8596f3f432d29f5f40930e 304 Gene3D G3DSA:3.40.50.1980 5 174 8.1E-45 T 13-09-2016 THL1_RS21125 9510d90c5c646c8f2878d2683d850928 480 Pfam PF00571 CBS domain 231 285 4.7E-9 T 13-09-2016 IPR000644 CBS domain THL1_RS21125 9510d90c5c646c8f2878d2683d850928 480 SMART SM00116 174 227 6.9 T 13-09-2016 IPR000644 CBS domain THL1_RS21125 9510d90c5c646c8f2878d2683d850928 480 SMART SM00116 238 286 4.9E-5 T 13-09-2016 IPR000644 CBS domain THL1_RS21125 9510d90c5c646c8f2878d2683d850928 480 Gene3D G3DSA:3.10.580.10 158 290 5.0E-18 T 13-09-2016 THL1_RS21125 9510d90c5c646c8f2878d2683d850928 480 Gene3D G3DSA:1.25.60.10 40 157 3.5E-25 T 13-09-2016 THL1_RS21125 9510d90c5c646c8f2878d2683d850928 480 Pfam PF01769 Divalent cation transporter 351 473 1.0E-23 T 13-09-2016 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 THL1_RS21125 9510d90c5c646c8f2878d2683d850928 480 Gene3D G3DSA:1.10.357.20 307 479 3.0E-54 T 13-09-2016 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 THL1_RS21125 9510d90c5c646c8f2878d2683d850928 480 SUPERFAMILY SSF54631 167 305 1.89E-28 T 13-09-2016 THL1_RS21125 9510d90c5c646c8f2878d2683d850928 480 PANTHER PTHR11911:SF99 1 460 7.6E-43 T 13-09-2016 THL1_RS21125 9510d90c5c646c8f2878d2683d850928 480 Pfam PF03448 MgtE intracellular N domain 64 165 9.7E-26 T 13-09-2016 IPR006668 Magnesium transporter, MgtE intracellular domain THL1_RS21125 9510d90c5c646c8f2878d2683d850928 480 PANTHER PTHR11911 1 460 7.6E-43 T 13-09-2016 THL1_RS21125 9510d90c5c646c8f2878d2683d850928 480 SMART SM00924 64 167 3.9E-35 T 13-09-2016 IPR006668 Magnesium transporter, MgtE intracellular domain THL1_RS21125 9510d90c5c646c8f2878d2683d850928 480 TIGRFAM TIGR00400 mgtE: magnesium transporter 45 479 6.3E-87 T 13-09-2016 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 THL1_RS21125 9510d90c5c646c8f2878d2683d850928 480 SUPERFAMILY SSF158791 41 164 2.22E-28 T 13-09-2016 THL1_RS21125 9510d90c5c646c8f2878d2683d850928 480 SUPERFAMILY SSF161093 308 479 1.01E-47 T 13-09-2016 THL1_RS15730 9c3ab82f52200fd6dfa296706b78bd56 175 SUPERFAMILY SSF52540 1 166 8.12E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15730 9c3ab82f52200fd6dfa296706b78bd56 175 Pfam PF13671 AAA domain 2 117 4.4E-12 T 13-09-2016 THL1_RS15730 9c3ab82f52200fd6dfa296706b78bd56 175 PANTHER PTHR37807 1 122 4.0E-13 T 13-09-2016 THL1_RS15730 9c3ab82f52200fd6dfa296706b78bd56 175 Gene3D G3DSA:3.40.50.300 1 166 5.6E-19 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18065 222749f5f74a3fe7e221d8ca7f8588db 869 Gene3D G3DSA:3.30.499.10 405 522 6.7E-64 T 13-09-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18065 222749f5f74a3fe7e221d8ca7f8588db 869 Gene3D G3DSA:3.20.19.10 162 360 2.1E-91 T 13-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THL1_RS18065 222749f5f74a3fe7e221d8ca7f8588db 869 ProSitePatterns PS00450 Aconitase family signature 1. 705 722 - T 13-09-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18065 222749f5f74a3fe7e221d8ca7f8588db 869 Gene3D G3DSA:3.30.499.10 687 867 2.5E-53 T 13-09-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18065 222749f5f74a3fe7e221d8ca7f8588db 869 SUPERFAMILY SSF74778 2 160 1.57E-67 T 13-09-2016 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747|UniPathway: UPA00223|UniPathway: UPA00946 THL1_RS18065 222749f5f74a3fe7e221d8ca7f8588db 869 Gene3D G3DSA:3.40.1060.10 523 685 8.2E-84 T 13-09-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18065 222749f5f74a3fe7e221d8ca7f8588db 869 Pfam PF11791 Aconitate B N-terminal domain 4 156 7.7E-66 T 13-09-2016 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747|UniPathway: UPA00223|UniPathway: UPA00946 THL1_RS18065 222749f5f74a3fe7e221d8ca7f8588db 869 PIRSF PIRSF036687 1 862 0.0 T 13-09-2016 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747|UniPathway: UPA00223|UniPathway: UPA00946 THL1_RS18065 222749f5f74a3fe7e221d8ca7f8588db 869 Pfam PF00330 Aconitase family (aconitate hydratase) 475 821 2.3E-40 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18065 222749f5f74a3fe7e221d8ca7f8588db 869 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 857 0.0 T 13-09-2016 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747|UniPathway: UPA00223|UniPathway: UPA00946 THL1_RS18065 222749f5f74a3fe7e221d8ca7f8588db 869 PANTHER PTHR11670:SF39 305 861 0.0 T 13-09-2016 THL1_RS18065 222749f5f74a3fe7e221d8ca7f8588db 869 SUPERFAMILY SSF52016 162 372 7.26E-71 T 13-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THL1_RS18065 222749f5f74a3fe7e221d8ca7f8588db 869 PANTHER PTHR11670 305 861 0.0 T 13-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18065 222749f5f74a3fe7e221d8ca7f8588db 869 SUPERFAMILY SSF53732 379 859 7.46E-148 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18065 222749f5f74a3fe7e221d8ca7f8588db 869 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 382 4.6E-95 T 13-09-2016 IPR015929 Aconitase B, N-terminal GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747|UniPathway: UPA00223|UniPathway: UPA00946 THL1_RS09905 cf2edb1b836d230364d2fd673d575ac7 398 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 245 258 - T 13-09-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 THL1_RS09905 cf2edb1b836d230364d2fd673d575ac7 398 Pfam PF00155 Aminotransferase class I and II 29 394 3.4E-79 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS09905 cf2edb1b836d230364d2fd673d575ac7 398 PANTHER PTHR11879:SF11 1 397 6.9E-245 T 13-09-2016 THL1_RS09905 cf2edb1b836d230364d2fd673d575ac7 398 PANTHER PTHR11879 1 397 6.9E-245 T 13-09-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 THL1_RS09905 cf2edb1b836d230364d2fd673d575ac7 398 PRINTS PR00799 Aspartate aminotransferase signature 343 361 8.8E-39 T 13-09-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 THL1_RS09905 cf2edb1b836d230364d2fd673d575ac7 398 PRINTS PR00799 Aspartate aminotransferase signature 177 196 8.8E-39 T 13-09-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 THL1_RS09905 cf2edb1b836d230364d2fd673d575ac7 398 PRINTS PR00799 Aspartate aminotransferase signature 275 300 8.8E-39 T 13-09-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 THL1_RS09905 cf2edb1b836d230364d2fd673d575ac7 398 PRINTS PR00799 Aspartate aminotransferase signature 208 220 8.8E-39 T 13-09-2016 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 THL1_RS09905 cf2edb1b836d230364d2fd673d575ac7 398 SUPERFAMILY SSF53383 1 397 5.2E-115 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS09905 cf2edb1b836d230364d2fd673d575ac7 398 Gene3D G3DSA:3.40.640.10 48 317 1.2E-106 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS01450 2a5b1adf6f73ac5b56333594ec994f61 223 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 53 217 1.3E-57 T 13-09-2016 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 THL1_RS01450 2a5b1adf6f73ac5b56333594ec994f61 223 Gene3D G3DSA:3.30.70.260 144 200 5.3E-30 T 13-09-2016 THL1_RS01450 2a5b1adf6f73ac5b56333594ec994f61 223 PANTHER PTHR11934 1 219 3.0E-133 T 13-09-2016 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 THL1_RS01450 2a5b1adf6f73ac5b56333594ec994f61 223 Gene3D G3DSA:3.40.50.1360 4 143 3.2E-55 T 13-09-2016 THL1_RS01450 2a5b1adf6f73ac5b56333594ec994f61 223 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 7 219 5.6E-63 T 13-09-2016 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 THL1_RS01450 2a5b1adf6f73ac5b56333594ec994f61 223 SUPERFAMILY SSF100950 1 150 1.4E-42 T 13-09-2016 THL1_RS01450 2a5b1adf6f73ac5b56333594ec994f61 223 SUPERFAMILY SSF75445 131 202 5.23E-24 T 13-09-2016 THL1_RS01450 2a5b1adf6f73ac5b56333594ec994f61 223 PANTHER PTHR11934:SF11 1 219 3.0E-133 T 13-09-2016 THL1_RS01450 2a5b1adf6f73ac5b56333594ec994f61 223 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 221 33.385 T 13-09-2016 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 THL1_RS14780 796d4d1859dc5c0bb6dd334d360f6ab5 308 PIRSF PIRSF028188 1 304 1.8E-107 T 13-09-2016 IPR014541 Predicted amidinotransferase, FN0238 type THL1_RS14780 796d4d1859dc5c0bb6dd334d360f6ab5 308 Pfam PF02274 Amidinotransferase 9 300 9.5E-72 T 13-09-2016 THL1_RS14780 796d4d1859dc5c0bb6dd334d360f6ab5 308 PANTHER PTHR12737 1 306 3.4E-81 T 13-09-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 THL1_RS14780 796d4d1859dc5c0bb6dd334d360f6ab5 308 Gene3D G3DSA:3.75.10.10 5 297 1.1E-21 T 13-09-2016 THL1_RS14780 796d4d1859dc5c0bb6dd334d360f6ab5 308 PANTHER PTHR12737:SF21 1 306 3.4E-81 T 13-09-2016 THL1_RS14780 796d4d1859dc5c0bb6dd334d360f6ab5 308 SUPERFAMILY SSF55909 4 300 3.02E-38 T 13-09-2016 THL1_RS12460 b2e8fb1f7916acfd06dbffb9ec07e8a1 130 PANTHER PTHR34874:SF1 1 129 8.3E-49 T 13-09-2016 THL1_RS12460 b2e8fb1f7916acfd06dbffb9ec07e8a1 130 TIGRFAM TIGR03012 sulf_tusD_dsrE: sulfur relay protein TusD/DsrE 2 127 3.9E-44 T 13-09-2016 IPR017463 Sulphur relay, TusD/DsrE GO:0005737|GO:0008033|GO:0016783 THL1_RS12460 b2e8fb1f7916acfd06dbffb9ec07e8a1 130 Pfam PF02635 DsrE/DsrF-like family 1 127 2.7E-21 T 13-09-2016 IPR003787 Sulphur relay, DsrE/F-like protein THL1_RS12460 b2e8fb1f7916acfd06dbffb9ec07e8a1 130 SUPERFAMILY SSF75169 1 127 1.31E-32 T 13-09-2016 IPR027396 DsrEFH-like THL1_RS12460 b2e8fb1f7916acfd06dbffb9ec07e8a1 130 Gene3D G3DSA:3.40.1260.10 1 127 4.0E-21 T 13-09-2016 IPR027396 DsrEFH-like THL1_RS12460 b2e8fb1f7916acfd06dbffb9ec07e8a1 130 PANTHER PTHR34874 1 129 8.3E-49 T 13-09-2016 THL1_RS21565 6dee9e593e229b22920d40d237f66cfe 405 TIGRFAM TIGR00032 argG: argininosuccinate synthase 6 398 3.9E-141 T 13-09-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS21565 6dee9e593e229b22920d40d237f66cfe 405 PANTHER PTHR11587 1 403 1.0E-232 T 13-09-2016 THL1_RS21565 6dee9e593e229b22920d40d237f66cfe 405 Gene3D G3DSA:3.90.1260.10 160 359 9.0E-97 T 13-09-2016 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS21565 6dee9e593e229b22920d40d237f66cfe 405 SUPERFAMILY SSF52402 5 209 2.65E-50 T 13-09-2016 THL1_RS21565 6dee9e593e229b22920d40d237f66cfe 405 Pfam PF00764 Arginosuccinate synthase 8 397 1.4E-154 T 13-09-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS21565 6dee9e593e229b22920d40d237f66cfe 405 PANTHER PTHR11587:SF2 1 403 1.0E-232 T 13-09-2016 THL1_RS21565 6dee9e593e229b22920d40d237f66cfe 405 Gene3D G3DSA:3.40.50.620 5 159 2.0E-66 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS21565 6dee9e593e229b22920d40d237f66cfe 405 SUPERFAMILY SSF69864 175 400 2.35E-93 T 13-09-2016 THL1_RS21565 6dee9e593e229b22920d40d237f66cfe 405 Hamap MF_00005 Argininosuccinate synthase [argG]. 4 402 52.417 T 13-09-2016 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS21565 6dee9e593e229b22920d40d237f66cfe 405 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 10 18 - T 13-09-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS21565 6dee9e593e229b22920d40d237f66cfe 405 Gene3D G3DSA:1.20.5.470 373 395 1.0E-5 T 13-09-2016 THL1_RS21565 6dee9e593e229b22920d40d237f66cfe 405 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 118 129 - T 13-09-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS12850 3ceaf8bd170aa264d59da21349d198d4 227 Gene3D G3DSA:3.40.50.2300 1 120 6.7E-41 T 13-09-2016 THL1_RS12850 3ceaf8bd170aa264d59da21349d198d4 227 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 221 1.5E-103 T 13-09-2016 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 THL1_RS12850 3ceaf8bd170aa264d59da21349d198d4 227 Gene3D G3DSA:1.10.10.10 123 223 4.2E-31 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12850 3ceaf8bd170aa264d59da21349d198d4 227 PANTHER PTHR26402 1 222 3.9E-102 T 13-09-2016 THL1_RS12850 3ceaf8bd170aa264d59da21349d198d4 227 SMART SM00448 1 112 2.5E-41 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS12850 3ceaf8bd170aa264d59da21349d198d4 227 SUPERFAMILY SSF52172 1 177 4.98E-41 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS12850 3ceaf8bd170aa264d59da21349d198d4 227 SMART SM00862 146 221 1.7E-25 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS12850 3ceaf8bd170aa264d59da21349d198d4 227 Pfam PF00072 Response regulator receiver domain 4 113 5.1E-27 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS12850 3ceaf8bd170aa264d59da21349d198d4 227 PANTHER PTHR26402:SF575 1 222 3.9E-102 T 13-09-2016 THL1_RS12850 3ceaf8bd170aa264d59da21349d198d4 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 1.2E-24 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 Pfam PF01627 Hpt domain 1104 1186 1.9E-9 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 Gene3D G3DSA:3.40.190.10 286 361 4.2E-17 T 13-09-2016 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 Gene3D G3DSA:3.40.190.10 466 503 4.2E-17 T 13-09-2016 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 Pfam PF00512 His Kinase A (phospho-acceptor) domain 695 761 2.0E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 SUPERFAMILY SSF53850 281 506 8.5E-36 T 13-09-2016 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 PANTHER PTHR24423:SF382 1 6 1.1E-167 T 13-09-2016 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 561 682 1.6E-11 T 13-09-2016 IPR000014 PAS domain THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 SMART SM00448 944 1060 3.6E-31 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 SMART SM00387 808 923 5.3E-33 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 SUPERFAMILY SSF53850 40 262 4.98E-26 T 13-09-2016 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 809 921 5.2E-25 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 SMART SM00073 1093 1189 2.6E-7 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 PRINTS PR00344 Bacterial sensor protein C-terminal signature 849 863 2.4E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 PRINTS PR00344 Bacterial sensor protein C-terminal signature 883 901 2.4E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 PRINTS PR00344 Bacterial sensor protein C-terminal signature 867 877 2.4E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 PRINTS PR00344 Bacterial sensor protein C-terminal signature 907 920 2.4E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 287 504 1.3E-29 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 48 259 3.3E-15 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 SUPERFAMILY SSF47226 1043 1056 2.09E-18 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 SUPERFAMILY SSF47226 1083 1166 2.09E-18 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 PANTHER PTHR24423 544 1102 1.1E-167 T 13-09-2016 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 Gene3D G3DSA:1.10.287.130 690 757 7.9E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 PANTHER PTHR24423:SF382 544 1102 1.1E-167 T 13-09-2016 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 Pfam PF08448 PAS fold 567 676 6.0E-15 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 SUPERFAMILY SSF47384 678 762 5.89E-18 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 SUPERFAMILY SSF55874 751 923 2.36E-40 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 Gene3D G3DSA:3.40.50.2300 941 1066 1.3E-36 T 13-09-2016 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 Gene3D G3DSA:3.30.565.10 762 924 7.5E-42 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 SUPERFAMILY SSF52172 942 1067 2.85E-35 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 PANTHER PTHR24423 1 6 1.1E-167 T 13-09-2016 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 Pfam PF00072 Response regulator receiver domain 946 1060 3.2E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 SMART SM00091 560 628 3.2E-4 T 13-09-2016 IPR000014 PAS domain THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 Gene3D G3DSA:1.20.120.160 1080 1190 5.3E-14 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 Gene3D G3DSA:3.40.190.10 362 447 8.6E-4 T 13-09-2016 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 SMART SM00388 695 761 1.3E-18 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 SMART SM00062 284 506 2.8E-16 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 SMART SM00062 45 261 7.6E-9 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 Gene3D G3DSA:3.40.190.10 40 156 6.7E-11 T 13-09-2016 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 Gene3D G3DSA:3.30.450.20 547 673 5.3E-17 T 13-09-2016 THL1_RS01860 39ede4dc4f376687e309c90f11ad905f 1198 SUPERFAMILY SSF55785 545 673 2.62E-19 T 13-09-2016 IPR000014 PAS domain THL1_RS21725 45221249ea0d7388c9ebfb5f440b6e4d 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 7.5E-18 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS21725 45221249ea0d7388c9ebfb5f440b6e4d 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.2E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS21725 45221249ea0d7388c9ebfb5f440b6e4d 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.2E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS21725 45221249ea0d7388c9ebfb5f440b6e4d 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.2E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS21725 45221249ea0d7388c9ebfb5f440b6e4d 305 PANTHER PTHR30126 1 305 2.4E-137 T 13-09-2016 THL1_RS21725 45221249ea0d7388c9ebfb5f440b6e4d 305 Gene3D G3DSA:3.40.190.10 89 181 2.0E-17 T 13-09-2016 THL1_RS21725 45221249ea0d7388c9ebfb5f440b6e4d 305 Gene3D G3DSA:3.40.190.10 182 261 7.0E-14 T 13-09-2016 THL1_RS21725 45221249ea0d7388c9ebfb5f440b6e4d 305 SUPERFAMILY SSF46785 1 112 4.54E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS21725 45221249ea0d7388c9ebfb5f440b6e4d 305 SUPERFAMILY SSF53850 88 287 2.95E-35 T 13-09-2016 THL1_RS21725 45221249ea0d7388c9ebfb5f440b6e4d 305 Pfam PF03466 LysR substrate binding domain 88 287 8.7E-36 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS21725 45221249ea0d7388c9ebfb5f440b6e4d 305 PANTHER PTHR30126:SF25 1 305 2.4E-137 T 13-09-2016 THL1_RS21725 45221249ea0d7388c9ebfb5f440b6e4d 305 Gene3D G3DSA:1.10.10.10 1 88 4.1E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 500 610 4.2E-16 T 13-09-2016 IPR000014 PAS domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 1220 1319 1.7E-17 T 13-09-2016 IPR000014 PAS domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 1084 1192 8.3E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 781 902 3.7E-21 T 13-09-2016 IPR000014 PAS domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SMART SM00267 1312 1484 3.3E-71 T 13-09-2016 IPR000160 GGDEF domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Gene3D G3DSA:3.30.450.20 781 893 2.7E-26 T 13-09-2016 THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Gene3D G3DSA:3.30.450.20 475 603 4.3E-19 T 13-09-2016 THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SMART SM00065 932 1076 6.3E-5 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SMART SM00065 624 780 4.3E-7 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Gene3D G3DSA:3.40.50.2300 1767 1895 6.2E-30 T 13-09-2016 THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SMART SM00086 855 896 0.0027 T 13-09-2016 IPR001610 PAC motif THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SMART SM00086 1270 1312 1.5E-11 T 13-09-2016 IPR001610 PAC motif THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SMART SM00086 568 606 31.0 T 13-09-2016 IPR001610 PAC motif THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SMART SM00052 1494 1740 7.7E-119 T 13-09-2016 IPR001633 EAL domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Gene3D G3DSA:3.30.450.20 1207 1312 4.1E-35 T 13-09-2016 THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SUPERFAMILY SSF55785 491 604 5.45E-16 T 13-09-2016 IPR000014 PAS domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Pfam PF13185 GAF domain 627 771 6.3E-16 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Pfam PF13185 GAF domain 932 1067 1.5E-11 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SUPERFAMILY SSF55785 771 893 3.63E-24 T 13-09-2016 IPR000014 PAS domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SUPERFAMILY SSF55781 914 1094 3.05E-19 T 13-09-2016 IPR029016 GAF domain-like THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 PANTHER PTHR33121 1436 1770 1.7E-91 T 13-09-2016 THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Pfam PF00072 Response regulator receiver domain 1769 1878 2.5E-21 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1323 1479 5.1E-51 T 13-09-2016 IPR000160 GGDEF domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1320 1482 6.6E-47 T 13-09-2016 IPR000160 GGDEF domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SUPERFAMILY SSF141868 1500 1749 2.22E-92 T 13-09-2016 IPR001633 EAL domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SUPERFAMILY SSF55785 1078 1185 4.33E-12 T 13-09-2016 IPR000014 PAS domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Gene3D G3DSA:3.30.450.20 1082 1185 5.3E-13 T 13-09-2016 THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SMART SM00448 1766 1878 2.0E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Pfam PF08447 PAS fold 520 586 6.2E-9 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SMART SM00091 496 562 2.4E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SMART SM00091 1087 1153 2.0E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SMART SM00091 784 850 3.3E-11 T 13-09-2016 IPR000014 PAS domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SMART SM00091 1195 1264 4.0E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Pfam PF00563 EAL domain 1500 1735 1.4E-72 T 13-09-2016 IPR001633 EAL domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Gene3D G3DSA:3.30.450.40 604 780 7.8E-24 T 13-09-2016 IPR029016 GAF domain-like THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Gene3D G3DSA:3.30.450.40 906 1081 1.3E-14 T 13-09-2016 IPR029016 GAF domain-like THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Pfam PF08448 PAS fold 1094 1141 8.7E-6 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Pfam PF08448 PAS fold 794 898 1.8E-13 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 PANTHER PTHR33121:SF13 1436 1770 1.7E-91 T 13-09-2016 THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Gene3D G3DSA:3.20.20.450 1498 1748 2.0E-97 T 13-09-2016 IPR001633 EAL domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SUPERFAMILY SSF55073 1328 1485 7.85E-52 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Pfam PF13426 PAS domain 1214 1311 5.2E-21 T 13-09-2016 IPR000014 PAS domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SUPERFAMILY SSF55785 1202 1312 1.68E-27 T 13-09-2016 IPR000014 PAS domain THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 Gene3D G3DSA:3.30.70.270 1325 1492 8.0E-61 T 13-09-2016 THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SUPERFAMILY SSF55781 599 772 5.67E-26 T 13-09-2016 IPR029016 GAF domain-like THL1_RS18935 5db0316d461e60dbdf7e02cf18c4f636 1902 SUPERFAMILY SSF52172 1766 1885 6.55E-30 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS27445 bb7946644a46a75b5816ccda0611d783 312 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 225 294 6.2E-24 T 13-09-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27445 bb7946644a46a75b5816ccda0611d783 312 Gene3D G3DSA:3.40.190.10 2 109 1.7E-48 T 13-09-2016 THL1_RS27445 bb7946644a46a75b5816ccda0611d783 312 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 13-09-2016 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27445 bb7946644a46a75b5816ccda0611d783 312 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 4 296 39.81 T 13-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27445 bb7946644a46a75b5816ccda0611d783 312 SUPERFAMILY SSF54782 219 308 2.62E-29 T 13-09-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27445 bb7946644a46a75b5816ccda0611d783 312 Gene3D G3DSA:3.40.190.10 110 198 1.9E-39 T 13-09-2016 THL1_RS27445 bb7946644a46a75b5816ccda0611d783 312 SUPERFAMILY SSF53850 3 218 1.93E-84 T 13-09-2016 THL1_RS27445 bb7946644a46a75b5816ccda0611d783 312 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 5 296 1.4E-113 T 13-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27445 bb7946644a46a75b5816ccda0611d783 312 PIRSF PIRSF001438 1 310 1.7E-122 T 13-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27445 bb7946644a46a75b5816ccda0611d783 312 PRINTS PR00151 Porphobilinogen deaminase signature 44 64 3.6E-51 T 13-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27445 bb7946644a46a75b5816ccda0611d783 312 PRINTS PR00151 Porphobilinogen deaminase signature 142 159 3.6E-51 T 13-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27445 bb7946644a46a75b5816ccda0611d783 312 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 3.6E-51 T 13-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27445 bb7946644a46a75b5816ccda0611d783 312 PRINTS PR00151 Porphobilinogen deaminase signature 75 94 3.6E-51 T 13-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27445 bb7946644a46a75b5816ccda0611d783 312 PRINTS PR00151 Porphobilinogen deaminase signature 123 140 3.6E-51 T 13-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27445 bb7946644a46a75b5816ccda0611d783 312 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 5 211 2.4E-79 T 13-09-2016 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27445 bb7946644a46a75b5816ccda0611d783 312 PANTHER PTHR11557 3 306 1.1E-162 T 13-09-2016 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27445 bb7946644a46a75b5816ccda0611d783 312 Gene3D G3DSA:3.30.160.40 220 304 2.1E-30 T 13-09-2016 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS00180 e78bc9f377d74bd1b9c074d6e0687968 71 Gene3D G3DSA:3.30.1660.10 4 70 2.5E-34 T 13-09-2016 IPR025543 Dodecin-like THL1_RS00180 e78bc9f377d74bd1b9c074d6e0687968 71 Pfam PF07311 Dodecin 6 68 8.3E-30 T 13-09-2016 IPR009923 Dodecin THL1_RS00180 e78bc9f377d74bd1b9c074d6e0687968 71 PANTHER PTHR39324 1 71 4.3E-26 T 13-09-2016 THL1_RS00180 e78bc9f377d74bd1b9c074d6e0687968 71 PANTHER PTHR39324:SF1 1 71 4.3E-26 T 13-09-2016 THL1_RS00180 e78bc9f377d74bd1b9c074d6e0687968 71 SUPERFAMILY SSF89807 6 70 1.44E-26 T 13-09-2016 IPR009923 Dodecin THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 Pfam PF02785 Biotin carboxylase C-terminal domain 337 445 1.6E-25 T 13-09-2016 IPR005482 Biotin carboxylase, C-terminal THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 Pfam PF00289 Biotin carboxylase, N-terminal domain 5 112 6.8E-41 T 13-09-2016 IPR005481 Biotin carboxylase-like, N-terminal domain THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 Gene3D G3DSA:3.30.470.20 202 449 1.2E-79 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 508 525 - T 13-09-2016 IPR001882 Biotin-binding site THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 SUPERFAMILY SSF51246 332 447 3.14E-26 T 13-09-2016 IPR011054 Rudiment single hybrid motif THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 SUPERFAMILY SSF56059 85 325 1.77E-62 T 13-09-2016 THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 Gene3D G3DSA:2.40.50.100 487 555 2.3E-16 T 13-09-2016 THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 SUPERFAMILY SSF52440 3 114 3.53E-40 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 Gene3D G3DSA:3.90.226.10 582 824 4.1E-41 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 Gene3D G3DSA:3.90.226.10 825 1077 4.5E-58 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 PANTHER PTHR18866:SF103 3 456 2.4E-226 T 13-09-2016 THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 SUPERFAMILY SSF51230 477 552 1.7E-15 T 13-09-2016 IPR011053 Single hybrid motif THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 Pfam PF01039 Carboxyl transferase domain 599 1071 3.7E-71 T 13-09-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 Gene3D G3DSA:3.30.1490.20 132 200 6.7E-20 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 Pfam PF00364 Biotin-requiring enzyme 487 549 2.0E-10 T 13-09-2016 IPR000089 Biotin/lipoyl attachment THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 322 1.1E-59 T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 SMART SM00878 337 444 1.4E-38 T 13-09-2016 IPR005482 Biotin carboxylase, C-terminal THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 SUPERFAMILY SSF52096 575 832 3.21E-52 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 SUPERFAMILY SSF52096 801 1069 1.46E-64 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 PANTHER PTHR18866 3 456 2.4E-226 T 13-09-2016 THL1_RS03905 4302955b99b3fc3adeea2952fabd78de 1089 Gene3D G3DSA:3.40.50.20 5 131 4.2E-46 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 Pfam PF10410 DnaB-helicase binding domain of primase 373 425 2.2E-9 T 13-09-2016 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 Pfam PF08278 DNA primase DnaG DnaB-binding 525 646 1.9E-29 T 13-09-2016 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 SMART SM00400 36 90 1.1E-32 T 13-09-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 PIRSF PIRSF002811 2 653 7.4E-152 T 13-09-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 Gene3D G3DSA:1.10.860.10 511 648 1.0E-40 T 13-09-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 SUPERFAMILY SSF117023 521 649 1.22E-34 T 13-09-2016 THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 PANTHER PTHR30313 3 429 3.3E-161 T 13-09-2016 THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 Pfam PF01807 CHC2 zinc finger 6 100 3.4E-40 T 13-09-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 TIGRFAM TIGR01391 dnaG: DNA primase 5 420 9.2E-144 T 13-09-2016 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 SMART SM00766 522 647 1.1E-37 T 13-09-2016 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 SMART SM00493 261 332 3.1E-21 T 13-09-2016 IPR006171 Toprim domain THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 Gene3D G3DSA:3.40.1360.10 243 367 8.6E-47 T 13-09-2016 THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 Gene3D G3DSA:3.90.580.10 2 101 8.5E-42 T 13-09-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 Pfam PF13662 Toprim domain 261 328 2.9E-17 T 13-09-2016 IPR006171 Toprim domain THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 Hamap MF_00974 DNA primase [dnaG]. 4 648 30.142 T 13-09-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 SUPERFAMILY SSF57783 4 101 3.57E-38 T 13-09-2016 THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 Gene3D G3DSA:3.90.980.10 116 242 7.9E-46 T 13-09-2016 IPR013264 DNA primase, catalytic core, N-terminal THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 Pfam PF08275 DNA primase catalytic core, N-terminal domain 126 253 4.8E-43 T 13-09-2016 IPR013264 DNA primase, catalytic core, N-terminal THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 SUPERFAMILY SSF56731 116 425 2.09E-108 T 13-09-2016 THL1_RS02535 7c59024e49fa18f2863f12276857413c 661 Gene3D G3DSA:1.20.50.20 371 428 3.4E-22 T 13-09-2016 THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 458 9.9E-218 T 13-09-2016 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 ProSitePatterns PS00163 Fumarate lyases signature. 315 324 - T 13-09-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 Hamap MF_00743 Fumarate hydratase class II [fumC]. 2 460 88.487 T 13-09-2016 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 Gene3D G3DSA:1.20.200.10 137 415 7.9E-102 T 13-09-2016 THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 PANTHER PTHR11444 3 459 2.6E-229 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 PRINTS PR00145 Argininosuccinate lyase family signature 131 153 1.2E-5 T 13-09-2016 THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 PRINTS PR00145 Argininosuccinate lyase family signature 173 193 1.2E-5 T 13-09-2016 THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 PRINTS PR00145 Argininosuccinate lyase family signature 315 331 1.2E-5 T 13-09-2016 THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 Gene3D G3DSA:1.10.40.30 416 460 1.5E-32 T 13-09-2016 THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 Pfam PF00206 Lyase 11 340 7.0E-102 T 13-09-2016 IPR022761 Fumarate lyase, N-terminal THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 PANTHER PTHR11444:SF1 3 459 2.6E-229 T 13-09-2016 THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 PRINTS PR00149 Fumarate lyase superfamily signature 132 150 2.7E-33 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 PRINTS PR00149 Fumarate lyase superfamily signature 178 196 2.7E-33 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 PRINTS PR00149 Fumarate lyase superfamily signature 269 296 2.7E-33 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 PRINTS PR00149 Fumarate lyase superfamily signature 315 331 2.7E-33 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 Gene3D G3DSA:1.10.275.10 2 136 7.6E-58 T 13-09-2016 IPR024083 Fumarase/histidase, N-terminal THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 SUPERFAMILY SSF48557 3 459 6.13E-154 T 13-09-2016 IPR008948 L-Aspartase-like GO:0003824 THL1_RS06955 e1d8a512ccc10a1e5659e7c6416c12f7 464 Pfam PF10415 Fumarase C C-terminus 406 458 6.8E-27 T 13-09-2016 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 THL1_RS01235 90975292c08ff9161091226b7c779fdb 264 PANTHER PTHR34266 4 264 3.3E-153 T 13-09-2016 THL1_RS01235 90975292c08ff9161091226b7c779fdb 264 Hamap MF_00443 Thiazole synthase [thiG]. 9 264 42.826 T 13-09-2016 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892|UniPathway: UPA00060 THL1_RS01235 90975292c08ff9161091226b7c779fdb 264 SUPERFAMILY SSF110399 9 250 2.49E-90 T 13-09-2016 IPR008867 Thiazole biosynthesis GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892|UniPathway: UPA00060 THL1_RS01235 90975292c08ff9161091226b7c779fdb 264 PANTHER PTHR34266:SF2 4 264 3.3E-153 T 13-09-2016 THL1_RS01235 90975292c08ff9161091226b7c779fdb 264 Gene3D G3DSA:3.20.20.70 18 239 1.1E-53 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS01235 90975292c08ff9161091226b7c779fdb 264 Pfam PF05690 Thiazole biosynthesis protein ThiG 12 258 7.3E-112 T 13-09-2016 THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 Pfam PF00175 Oxidoreductase NAD-binding domain 114 200 1.3E-5 T 13-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 Gene3D G3DSA:2.40.30.10 8 102 2.1E-32 T 13-09-2016 THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 241 311 3.1E-13 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 PANTHER PTHR19370:SF113 8 240 4.5E-61 T 13-09-2016 THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 SUPERFAMILY SSF54292 213 320 2.88E-27 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 SUPERFAMILY SSF52343 100 224 4.06E-28 T 13-09-2016 THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 Gene3D G3DSA:3.10.20.30 217 316 1.5E-27 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 Gene3D G3DSA:3.40.50.80 107 216 5.0E-25 T 13-09-2016 THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 42 54 1.8E-32 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 113 132 1.8E-32 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 189 197 1.8E-32 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 54 68 1.8E-32 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 32 42 1.8E-32 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 78 92 1.8E-32 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 PRINTS PR00409 Phthalate dioxygenase reductase family signature 138 147 1.8E-32 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 269 277 - T 13-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 PANTHER PTHR19370 8 240 4.5E-61 T 13-09-2016 THL1_RS12720 c50f0abaa81f6e1851a30532a2504032 320 SUPERFAMILY SSF63380 8 102 5.2E-26 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS00260 df4a04386bcbb288b72cf8bfc0afa3b0 183 Gene3D G3DSA:2.60.370.10 54 178 4.1E-48 T 13-09-2016 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain THL1_RS00260 df4a04386bcbb288b72cf8bfc0afa3b0 183 SUPERFAMILY SSF110111 54 173 2.62E-46 T 13-09-2016 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain THL1_RS00260 df4a04386bcbb288b72cf8bfc0afa3b0 183 PIRSF PIRSF005413 1 182 5.7E-65 T 13-09-2016 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 THL1_RS00260 df4a04386bcbb288b72cf8bfc0afa3b0 183 Pfam PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11 28 170 3.6E-49 T 13-09-2016 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 THL1_RS00260 df4a04386bcbb288b72cf8bfc0afa3b0 183 PANTHER PTHR21320 4 171 3.9E-44 T 13-09-2016 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 THL1_RS00260 df4a04386bcbb288b72cf8bfc0afa3b0 183 PANTHER PTHR21320:SF3 4 171 3.9E-44 T 13-09-2016 THL1_RS01730 35463735ce5070609cf57f6482f15d1a 514 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 1 491 4.7E-173 T 13-09-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 THL1_RS01730 35463735ce5070609cf57f6482f15d1a 514 PANTHER PTHR30047:SF6 1 498 4.4E-294 T 13-09-2016 THL1_RS01730 35463735ce5070609cf57f6482f15d1a 514 PANTHER PTHR30047 1 498 4.4E-294 T 13-09-2016 THL1_RS01730 35463735ce5070609cf57f6482f15d1a 514 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 39 493 7.3E-152 T 13-09-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 THL1_RS17215 3e8955098142d50ac03611c2d5ccd33b 590 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 163 272 1.0E-15 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS17215 3e8955098142d50ac03611c2d5ccd33b 590 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 32 1.2E-10 T 13-09-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria THL1_RS17215 3e8955098142d50ac03611c2d5ccd33b 590 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 42 158 6.7E-11 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS17215 3e8955098142d50ac03611c2d5ccd33b 590 PANTHER PTHR10909 1 477 5.6E-256 T 13-09-2016 THL1_RS17215 3e8955098142d50ac03611c2d5ccd33b 590 Gene3D G3DSA:1.10.540.10 42 160 1.9E-13 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS17215 3e8955098142d50ac03611c2d5ccd33b 590 SUPERFAMILY SSF47203 289 475 4.03E-48 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS17215 3e8955098142d50ac03611c2d5ccd33b 590 Gene3D G3DSA:1.20.140.10 269 464 1.3E-53 T 13-09-2016 THL1_RS17215 3e8955098142d50ac03611c2d5ccd33b 590 PANTHER PTHR10909:SF296 1 477 5.6E-256 T 13-09-2016 THL1_RS17215 3e8955098142d50ac03611c2d5ccd33b 590 Gene3D G3DSA:2.40.110.10 162 268 4.1E-26 T 13-09-2016 THL1_RS17215 3e8955098142d50ac03611c2d5ccd33b 590 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 283 452 3.0E-22 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS17215 3e8955098142d50ac03611c2d5ccd33b 590 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 468 585 4.5E-30 T 13-09-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain THL1_RS17215 3e8955098142d50ac03611c2d5ccd33b 590 SUPERFAMILY SSF56645 40 281 5.89E-53 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS16735 94c8c7dcc941bc08577c1e17e01cfda7 188 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 3 180 1.6E-27 T 13-09-2016 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 THL1_RS16735 94c8c7dcc941bc08577c1e17e01cfda7 188 PANTHER PTHR36122 1 181 2.4E-71 T 13-09-2016 THL1_RS16735 94c8c7dcc941bc08577c1e17e01cfda7 188 Pfam PF04973 Nicotinamide mononucleotide transporter 3 181 6.5E-55 T 13-09-2016 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 THL1_RS16735 94c8c7dcc941bc08577c1e17e01cfda7 188 PANTHER PTHR36122:SF1 1 181 2.4E-71 T 13-09-2016 THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 PANTHER PTHR24078:SF231 1 370 8.7E-171 T 13-09-2016 THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 13-09-2016 IPR018253 DnaJ domain, conserved site THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 SUPERFAMILY SSF46565 1 111 4.58E-36 T 13-09-2016 IPR001623 DnaJ domain THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 Gene3D G3DSA:2.60.260.20 108 140 3.8E-23 T 13-09-2016 THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 Gene3D G3DSA:2.60.260.20 211 254 3.8E-23 T 13-09-2016 THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 Gene3D G3DSA:2.60.260.20 256 333 4.0E-23 T 13-09-2016 THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 SUPERFAMILY SSF49493 213 267 2.62E-21 T 13-09-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 SUPERFAMILY SSF49493 114 152 2.62E-21 T 13-09-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 371 42.5 T 13-09-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 SMART SM00271 4 62 1.5E-32 T 13-09-2016 IPR001623 DnaJ domain THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 SUPERFAMILY SSF49493 259 344 3.79E-22 T 13-09-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 Pfam PF01556 DnaJ C terminal domain 121 333 3.2E-44 T 13-09-2016 IPR002939 Chaperone DnaJ, C-terminal THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 PRINTS PR00625 DnaJ domain signature 42 62 6.7E-32 T 13-09-2016 IPR001623 DnaJ domain THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 PRINTS PR00625 DnaJ domain signature 25 40 6.7E-32 T 13-09-2016 IPR001623 DnaJ domain THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 PRINTS PR00625 DnaJ domain signature 7 25 6.7E-32 T 13-09-2016 IPR001623 DnaJ domain THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 PRINTS PR00625 DnaJ domain signature 62 81 6.7E-32 T 13-09-2016 IPR001623 DnaJ domain THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 SUPERFAMILY SSF57938 134 211 1.83E-22 T 13-09-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 Pfam PF00684 DnaJ central domain 147 207 1.0E-13 T 13-09-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 349 2.5E-139 T 13-09-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 PANTHER PTHR24078 1 370 8.7E-171 T 13-09-2016 THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 Gene3D G3DSA:2.10.230.10 141 210 5.8E-24 T 13-09-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 Gene3D G3DSA:1.10.287.110 1 103 6.7E-36 T 13-09-2016 IPR001623 DnaJ domain THL1_RS24485 b584cd9caa8c4a1a92d93c62ff9b1d16 375 Pfam PF00226 DnaJ domain 5 67 1.2E-27 T 13-09-2016 IPR001623 DnaJ domain THL1_RS23425 5f956d31a71143fd34126ef98a7bc33b 97 SMART SM00883 2 95 6.4E-57 T 13-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THL1_RS23425 5f956d31a71143fd34126ef98a7bc33b 97 Hamap MF_00580 10 kDa chaperonin [groS]. 2 96 26.918 T 13-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THL1_RS23425 5f956d31a71143fd34126ef98a7bc33b 97 SUPERFAMILY SSF50129 1 96 1.77E-34 T 13-09-2016 IPR011032 GroES-like THL1_RS23425 5f956d31a71143fd34126ef98a7bc33b 97 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 13-09-2016 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 THL1_RS23425 5f956d31a71143fd34126ef98a7bc33b 97 Gene3D G3DSA:2.30.33.40 1 96 5.6E-36 T 13-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THL1_RS23425 5f956d31a71143fd34126ef98a7bc33b 97 PANTHER PTHR10772 1 96 8.8E-43 T 13-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THL1_RS23425 5f956d31a71143fd34126ef98a7bc33b 97 PRINTS PR00297 10kDa chaperonin signature 25 46 2.9E-31 T 13-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THL1_RS23425 5f956d31a71143fd34126ef98a7bc33b 97 PRINTS PR00297 10kDa chaperonin signature 60 72 2.9E-31 T 13-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THL1_RS23425 5f956d31a71143fd34126ef98a7bc33b 97 PRINTS PR00297 10kDa chaperonin signature 3 18 2.9E-31 T 13-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THL1_RS23425 5f956d31a71143fd34126ef98a7bc33b 97 PRINTS PR00297 10kDa chaperonin signature 82 95 2.9E-31 T 13-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THL1_RS23425 5f956d31a71143fd34126ef98a7bc33b 97 Pfam PF00166 Chaperonin 10 Kd subunit 2 95 8.9E-33 T 13-09-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THL1_RS26015 d3a21bf2549aa323e4f73cfe0edc7a3a 340 PANTHER PTHR30222:SF2 5 339 2.8E-152 T 13-09-2016 THL1_RS26015 d3a21bf2549aa323e4f73cfe0edc7a3a 340 Gene3D G3DSA:3.40.190.10 28 133 4.2E-5 T 13-09-2016 THL1_RS26015 d3a21bf2549aa323e4f73cfe0edc7a3a 340 SUPERFAMILY SSF53850 22 336 9.97E-59 T 13-09-2016 THL1_RS26015 d3a21bf2549aa323e4f73cfe0edc7a3a 340 Gene3D G3DSA:3.40.190.10 134 279 1.7E-33 T 13-09-2016 THL1_RS26015 d3a21bf2549aa323e4f73cfe0edc7a3a 340 PANTHER PTHR30222 5 339 2.8E-152 T 13-09-2016 THL1_RS26015 d3a21bf2549aa323e4f73cfe0edc7a3a 340 Pfam PF13416 Bacterial extracellular solute-binding protein 41 290 3.0E-39 T 13-09-2016 THL1_RS07630 ac3f43b46cfc36393e6e25980692f7b4 237 SUPERFAMILY SSF100950 17 232 5.08E-54 T 13-09-2016 THL1_RS07630 ac3f43b46cfc36393e6e25980692f7b4 237 Gene3D G3DSA:3.40.50.1360 13 228 1.4E-51 T 13-09-2016 THL1_RS07630 ac3f43b46cfc36393e6e25980692f7b4 237 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 19 235 7.8E-53 T 13-09-2016 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 THL1_RS07630 ac3f43b46cfc36393e6e25980692f7b4 237 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 129 147 - T 13-09-2016 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 THL1_RS07630 ac3f43b46cfc36393e6e25980692f7b4 237 PANTHER PTHR11054 19 235 7.1E-45 T 13-09-2016 THL1_RS07630 ac3f43b46cfc36393e6e25980692f7b4 237 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 21 229 4.0E-58 T 13-09-2016 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31|UniPathway: UPA00115 THL1_RS14615 9116119cb768d71060ba4cb0970d798e 390 SUPERFAMILY SSF52540 46 271 2.35E-75 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14615 9116119cb768d71060ba4cb0970d798e 390 PANTHER PTHR24220:SF374 9 19 9.5E-148 T 13-09-2016 THL1_RS14615 9116119cb768d71060ba4cb0970d798e 390 Gene3D G3DSA:3.10.580.10 339 389 6.1E-5 T 13-09-2016 THL1_RS14615 9116119cb768d71060ba4cb0970d798e 390 Pfam PF00005 ABC transporter 49 195 2.0E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS14615 9116119cb768d71060ba4cb0970d798e 390 PANTHER PTHR24220 44 277 9.5E-148 T 13-09-2016 THL1_RS14615 9116119cb768d71060ba4cb0970d798e 390 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS14615 9116119cb768d71060ba4cb0970d798e 390 Gene3D G3DSA:3.40.50.300 41 268 8.3E-78 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14615 9116119cb768d71060ba4cb0970d798e 390 PANTHER PTHR24220:SF374 44 277 9.5E-148 T 13-09-2016 THL1_RS14615 9116119cb768d71060ba4cb0970d798e 390 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 40 388 3.7E-124 T 13-09-2016 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 THL1_RS14615 9116119cb768d71060ba4cb0970d798e 390 PANTHER PTHR24220 9 19 9.5E-148 T 13-09-2016 THL1_RS14615 9116119cb768d71060ba4cb0970d798e 390 SMART SM00382 56 253 7.7E-16 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS25910 5bfba8b456a00223a5f128ea9a146120 283 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 13-09-2016 IPR000540 Flagellar motor protein MotA, conserved site THL1_RS25910 5bfba8b456a00223a5f128ea9a146120 283 Pfam PF01618 MotA/TolQ/ExbB proton channel family 138 237 1.0E-8 T 13-09-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 THL1_RS25910 5bfba8b456a00223a5f128ea9a146120 283 PANTHER PTHR30433:SF4 1 281 1.1E-146 T 13-09-2016 IPR022522 Flagellar motor stator, MotA THL1_RS25910 5bfba8b456a00223a5f128ea9a146120 283 PANTHER PTHR30433 1 281 1.1E-146 T 13-09-2016 THL1_RS25910 5bfba8b456a00223a5f128ea9a146120 283 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 1 281 3.1E-111 T 13-09-2016 IPR022522 Flagellar motor stator, MotA THL1_RS23545 f3a8db010ffeb7976c5a0b32d22f19a3 262 SUPERFAMILY SSF54427 12 121 8.79E-18 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS23545 f3a8db010ffeb7976c5a0b32d22f19a3 262 Pfam PF12833 Helix-turn-helix domain 178 258 2.2E-18 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS23545 f3a8db010ffeb7976c5a0b32d22f19a3 262 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 208 252 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS23545 f3a8db010ffeb7976c5a0b32d22f19a3 262 PANTHER PTHR11019:SF65 167 261 1.2E-15 T 13-09-2016 THL1_RS23545 f3a8db010ffeb7976c5a0b32d22f19a3 262 Pfam PF12680 SnoaL-like domain 21 116 1.5E-9 T 13-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain THL1_RS23545 f3a8db010ffeb7976c5a0b32d22f19a3 262 Gene3D G3DSA:1.10.10.60 209 259 8.8E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS23545 f3a8db010ffeb7976c5a0b32d22f19a3 262 SMART SM00342 171 256 2.3E-18 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS23545 f3a8db010ffeb7976c5a0b32d22f19a3 262 SUPERFAMILY SSF46689 208 258 3.23E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS23545 f3a8db010ffeb7976c5a0b32d22f19a3 262 PANTHER PTHR11019 167 261 1.2E-15 T 13-09-2016 THL1_RS23545 f3a8db010ffeb7976c5a0b32d22f19a3 262 Gene3D G3DSA:1.10.10.60 171 208 6.0E-5 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS23545 f3a8db010ffeb7976c5a0b32d22f19a3 262 Gene3D G3DSA:3.10.450.50 11 120 5.9E-15 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS06970 c17573d6d306180fa4d6a0b0efb4a9c8 101 Gene3D G3DSA:3.30.300.90 1 97 3.4E-29 T 13-09-2016 IPR002634 BolA protein THL1_RS06970 c17573d6d306180fa4d6a0b0efb4a9c8 101 SUPERFAMILY SSF82657 2 84 3.14E-28 T 13-09-2016 IPR002634 BolA protein THL1_RS06970 c17573d6d306180fa4d6a0b0efb4a9c8 101 PANTHER PTHR12735 2 99 7.2E-33 T 13-09-2016 THL1_RS06970 c17573d6d306180fa4d6a0b0efb4a9c8 101 PIRSF PIRSF003113 1 95 3.2E-30 T 13-09-2016 IPR002634 BolA protein THL1_RS06970 c17573d6d306180fa4d6a0b0efb4a9c8 101 PANTHER PTHR12735:SF3 2 99 7.2E-33 T 13-09-2016 THL1_RS06970 c17573d6d306180fa4d6a0b0efb4a9c8 101 Pfam PF01722 BolA-like protein 12 80 1.7E-24 T 13-09-2016 IPR002634 BolA protein THL1_RS06720 7b26fdad8ec8c1b6aca9a23efbea8fe1 251 Gene3D G3DSA:3.40.190.10 114 210 1.2E-38 T 13-09-2016 THL1_RS06720 7b26fdad8ec8c1b6aca9a23efbea8fe1 251 PIRSF PIRSF004846 2 251 8.9E-58 T 13-09-2016 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 THL1_RS06720 7b26fdad8ec8c1b6aca9a23efbea8fe1 251 PANTHER PTHR30632 4 250 8.4E-47 T 13-09-2016 THL1_RS06720 7b26fdad8ec8c1b6aca9a23efbea8fe1 251 Gene3D G3DSA:3.40.190.10 211 250 9.5E-15 T 13-09-2016 THL1_RS06720 7b26fdad8ec8c1b6aca9a23efbea8fe1 251 Gene3D G3DSA:3.40.190.10 25 113 9.5E-15 T 13-09-2016 THL1_RS06720 7b26fdad8ec8c1b6aca9a23efbea8fe1 251 PANTHER PTHR30632:SF0 4 250 8.4E-47 T 13-09-2016 THL1_RS06720 7b26fdad8ec8c1b6aca9a23efbea8fe1 251 SUPERFAMILY SSF53850 25 249 2.61E-65 T 13-09-2016 THL1_RS06720 7b26fdad8ec8c1b6aca9a23efbea8fe1 251 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 31 248 5.8E-80 T 13-09-2016 IPR005950 Molybdenum ABC transporter, periplasmic binding protein GO:0015412|GO:0015689|GO:0030288 THL1_RS06720 7b26fdad8ec8c1b6aca9a23efbea8fe1 251 Pfam PF13531 Bacterial extracellular solute-binding protein 27 250 1.6E-46 T 13-09-2016 THL1_RS04585 435708013f18775b4fa8c8fa411c6dfd 184 PANTHER PTHR18901:SF25 1 171 3.6E-77 T 13-09-2016 THL1_RS04585 435708013f18775b4fa8c8fa411c6dfd 184 PANTHER PTHR18901 1 171 3.6E-77 T 13-09-2016 THL1_RS04585 435708013f18775b4fa8c8fa411c6dfd 184 Gene3D G3DSA:3.40.50.1000 25 181 2.9E-27 T 13-09-2016 IPR023214 HAD-like domain THL1_RS04585 435708013f18775b4fa8c8fa411c6dfd 184 Pfam PF13419 Haloacid dehalogenase-like hydrolase 24 158 4.4E-15 T 13-09-2016 IPR023214 HAD-like domain THL1_RS04585 435708013f18775b4fa8c8fa411c6dfd 184 SUPERFAMILY SSF56784 1 183 7.7E-32 T 13-09-2016 IPR023214 HAD-like domain THL1_RS12995 0108314cc5d6b371297987e1ad6cf75a 217 PANTHER PTHR23026:SF101 1 215 1.4E-79 T 13-09-2016 THL1_RS12995 0108314cc5d6b371297987e1ad6cf75a 217 Pfam PF00881 Nitroreductase family 8 192 2.6E-27 T 13-09-2016 IPR029479 Nitroreductase THL1_RS12995 0108314cc5d6b371297987e1ad6cf75a 217 PANTHER PTHR23026 1 215 1.4E-79 T 13-09-2016 THL1_RS12995 0108314cc5d6b371297987e1ad6cf75a 217 SUPERFAMILY SSF55469 1 215 9.55E-66 T 13-09-2016 IPR000415 Nitroreductase-like GO:0016491 THL1_RS12995 0108314cc5d6b371297987e1ad6cf75a 217 Gene3D G3DSA:3.40.109.10 5 215 1.0E-62 T 13-09-2016 IPR000415 Nitroreductase-like GO:0016491 THL1_RS08590 513182fefb41831e7d240e1df42a6814 363 SUPERFAMILY SSF52540 144 330 4.84E-5 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08590 513182fefb41831e7d240e1df42a6814 363 SUPERFAMILY SSF52821 92 156 5.76E-18 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS08590 513182fefb41831e7d240e1df42a6814 363 SUPERFAMILY SSF52821 5 64 5.76E-18 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS08590 513182fefb41831e7d240e1df42a6814 363 PANTHER PTHR30401 5 363 1.7E-184 T 13-09-2016 THL1_RS08590 513182fefb41831e7d240e1df42a6814 363 TIGRFAM TIGR03167 tRNA_sel_U_synt: tRNA 2-selenouridine synthase 16 348 2.3E-107 T 13-09-2016 IPR017582 tRNA 2-selenouridine synthase GO:0016785|GO:0043828|GO:0070329 THL1_RS08590 513182fefb41831e7d240e1df42a6814 363 Gene3D G3DSA:3.40.250.10 14 132 3.0E-27 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS08590 513182fefb41831e7d240e1df42a6814 363 Hamap MF_01622 tRNA 2-selenouridine synthase [selU]. 1 363 53.966 T 13-09-2016 IPR017582 tRNA 2-selenouridine synthase GO:0016785|GO:0043828|GO:0070329 THL1_RS08590 513182fefb41831e7d240e1df42a6814 363 SMART SM00450 2 133 9.3E-6 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS08590 513182fefb41831e7d240e1df42a6814 363 PANTHER PTHR30401:SF0 5 363 1.7E-184 T 13-09-2016 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 PANTHER PTHR32063:SF13 1 1044 0.0 T 13-09-2016 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 Pfam PF00873 AcrB/AcrD/AcrF family 1 1025 0.0 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 Gene3D G3DSA:3.30.2090.10 721 809 2.4E-27 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1040 0.0 T 13-09-2016 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0005215|GO:0006810|GO:0016021 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 Gene3D G3DSA:1.20.1640.10 291 504 3.1E-57 T 13-09-2016 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 SUPERFAMILY SSF82866 296 497 1.06E-48 T 13-09-2016 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 Gene3D G3DSA:1.10.3850.10 814 1025 9.8E-59 T 13-09-2016 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 SUPERFAMILY SSF82714 182 271 2.75E-21 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 Gene3D G3DSA:3.30.70.1430 567 670 4.6E-38 T 13-09-2016 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 SUPERFAMILY SSF82693 38 130 3.14E-27 T 13-09-2016 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 Gene3D G3DSA:3.30.2090.10 181 275 5.5E-26 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 PANTHER PTHR32063 1 1044 0.0 T 13-09-2016 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 SUPERFAMILY SSF82693 565 669 3.56E-32 T 13-09-2016 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 Gene3D G3DSA:3.30.70.1430 38 139 9.5E-34 T 13-09-2016 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 SUPERFAMILY SSF82693 135 182 5.49E-27 T 13-09-2016 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 SUPERFAMILY SSF82693 274 330 5.49E-27 T 13-09-2016 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 2.0E-111 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 2.0E-111 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 2.0E-111 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 2.0E-111 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 PRINTS PR00702 Acriflavin resistance protein family signature 621 635 2.0E-111 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 2.0E-111 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 2.0E-111 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 2.0E-111 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 2.0E-111 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 SUPERFAMILY SSF82866 806 1026 4.45E-48 T 13-09-2016 THL1_RS21755 a8b71c2277ef91d940fe9c64996f33c4 1044 SUPERFAMILY SSF82714 722 809 2.62E-23 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS09440 498a9102b2cf079f83faab6bbb41f281 331 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 6 331 1.6E-110 T 13-09-2016 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 THL1_RS09440 498a9102b2cf079f83faab6bbb41f281 331 Pfam PF06463 Molybdenum Cofactor Synthesis C 186 313 1.2E-36 T 13-09-2016 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 THL1_RS09440 498a9102b2cf079f83faab6bbb41f281 331 PANTHER PTHR22960 3 283 1.5E-119 T 13-09-2016 THL1_RS09440 498a9102b2cf079f83faab6bbb41f281 331 SMART SM00729 15 219 1.7E-12 T 13-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THL1_RS09440 498a9102b2cf079f83faab6bbb41f281 331 Hamap MF_01225_B Cyclic pyranopterin monophosphate synthase [moaA]. 6 331 40.452 T 13-09-2016 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 THL1_RS09440 498a9102b2cf079f83faab6bbb41f281 331 Gene3D G3DSA:3.20.20.70 5 288 4.6E-71 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS09440 498a9102b2cf079f83faab6bbb41f281 331 SUPERFAMILY SSF102114 6 278 2.35E-73 T 13-09-2016 THL1_RS09440 498a9102b2cf079f83faab6bbb41f281 331 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 21 32 - T 13-09-2016 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 THL1_RS09440 498a9102b2cf079f83faab6bbb41f281 331 Pfam PF04055 Radical SAM superfamily 20 179 2.0E-28 T 13-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 THL1_RS09440 498a9102b2cf079f83faab6bbb41f281 331 Pfam PF13353 4Fe-4S single cluster domain 22 114 1.7E-7 T 13-09-2016 THL1_RS26880 354a8acc07d000548de418f498bb9c54 249 SUPERFAMILY SSF50249 10 72 5.63E-13 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS26880 354a8acc07d000548de418f498bb9c54 249 Pfam PF00313 'Cold-shock' DNA-binding domain 13 71 2.3E-11 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS26880 354a8acc07d000548de418f498bb9c54 249 SMART SM00357 13 73 1.2E-8 T 13-09-2016 IPR011129 Cold shock protein GO:0003676 THL1_RS26880 354a8acc07d000548de418f498bb9c54 249 Gene3D G3DSA:2.40.50.140 12 72 6.5E-17 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS19715 6c5d76565a33a0ac77e8da8e2796a9c6 148 PANTHER PTHR30435:SF2 1 148 9.9E-67 T 13-09-2016 THL1_RS19715 6c5d76565a33a0ac77e8da8e2796a9c6 148 Pfam PF00460 Flagella basal body rod protein 7 34 2.6E-8 T 13-09-2016 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 THL1_RS19715 6c5d76565a33a0ac77e8da8e2796a9c6 148 PANTHER PTHR30435 1 148 9.9E-67 T 13-09-2016 THL1_RS19715 6c5d76565a33a0ac77e8da8e2796a9c6 148 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 13-09-2016 IPR019776 Flagellar basal body rod protein, conserved site THL1_RS19715 6c5d76565a33a0ac77e8da8e2796a9c6 148 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 5 148 1.7E-49 T 13-09-2016 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 THL1_RS19715 6c5d76565a33a0ac77e8da8e2796a9c6 148 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 101 146 8.1E-14 T 13-09-2016 IPR010930 Flagellar basal-body/hook protein, C-terminal domain THL1_RS17560 527b99ee17f5dce9aad72a98ffbeff7a 118 PANTHER PTHR30204:SF15 11 118 1.2E-34 T 13-09-2016 THL1_RS17560 527b99ee17f5dce9aad72a98ffbeff7a 118 Gene3D G3DSA:1.10.1660.10 19 116 1.7E-18 T 13-09-2016 THL1_RS17560 527b99ee17f5dce9aad72a98ffbeff7a 118 SMART SM00422 19 89 2.9E-9 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS17560 527b99ee17f5dce9aad72a98ffbeff7a 118 SUPERFAMILY SSF46955 19 117 1.01E-20 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS17560 527b99ee17f5dce9aad72a98ffbeff7a 118 PANTHER PTHR30204 11 118 1.2E-34 T 13-09-2016 THL1_RS17560 527b99ee17f5dce9aad72a98ffbeff7a 118 Pfam PF13411 MerR HTH family regulatory protein 19 87 2.9E-23 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS11830 538f9b6be4d40f8e79d69601dab20649 324 Gene3D G3DSA:1.10.10.10 1 82 1.2E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11830 538f9b6be4d40f8e79d69601dab20649 324 SUPERFAMILY SSF53850 90 320 4.64E-43 T 13-09-2016 THL1_RS11830 538f9b6be4d40f8e79d69601dab20649 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 7.2E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS11830 538f9b6be4d40f8e79d69601dab20649 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 7.2E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS11830 538f9b6be4d40f8e79d69601dab20649 324 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 7.2E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS11830 538f9b6be4d40f8e79d69601dab20649 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 6.9E-16 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS11830 538f9b6be4d40f8e79d69601dab20649 324 Gene3D G3DSA:3.40.190.10 90 183 3.6E-23 T 13-09-2016 THL1_RS11830 538f9b6be4d40f8e79d69601dab20649 324 PANTHER PTHR30126:SF6 1 309 7.4E-206 T 13-09-2016 THL1_RS11830 538f9b6be4d40f8e79d69601dab20649 324 Pfam PF03466 LysR substrate binding domain 89 266 3.4E-41 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS11830 538f9b6be4d40f8e79d69601dab20649 324 PANTHER PTHR30126 1 309 7.4E-206 T 13-09-2016 THL1_RS11830 538f9b6be4d40f8e79d69601dab20649 324 SUPERFAMILY SSF46785 1 112 4.98E-15 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11830 538f9b6be4d40f8e79d69601dab20649 324 Gene3D G3DSA:3.40.190.10 184 262 5.9E-29 T 13-09-2016 THL1_RS26240 41bdcd214ad77776da4905260e3fa44c 232 SUPERFAMILY SSF53681 105 215 2.94E-23 T 13-09-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS26240 41bdcd214ad77776da4905260e3fa44c 232 PANTHER PTHR21198 1 228 3.4E-62 T 13-09-2016 THL1_RS26240 41bdcd214ad77776da4905260e3fa44c 232 Gene3D G3DSA:3.40.50.1860 1 112 1.6E-39 T 13-09-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS26240 41bdcd214ad77776da4905260e3fa44c 232 Gene3D G3DSA:3.40.50.1860 113 216 3.3E-26 T 13-09-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS26240 41bdcd214ad77776da4905260e3fa44c 232 PANTHER PTHR21198:SF7 1 228 3.4E-62 T 13-09-2016 THL1_RS26240 41bdcd214ad77776da4905260e3fa44c 232 SUPERFAMILY SSF53681 1 116 2.42E-32 T 13-09-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS26240 41bdcd214ad77776da4905260e3fa44c 232 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 222 2.4E-51 T 13-09-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS26240 41bdcd214ad77776da4905260e3fa44c 232 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 226 4.7E-51 T 13-09-2016 IPR004380 Aspartate racemase GO:0006520|GO:0016855 THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 Gene3D G3DSA:3.30.70.870 295 372 2.3E-26 T 13-09-2016 THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 TIGRFAM TIGR01393 lepA: elongation factor 4 6 598 7.5E-293 T 13-09-2016 IPR006297 Elongation factor 4 GO:0005525 THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 Pfam PF03144 Elongation factor Tu domain 2 208 278 1.0E-10 T 13-09-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 PANTHER PTHR23115 400 598 3.4E-275 T 13-09-2016 THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 PANTHER PTHR23115:SF175 7 376 3.4E-275 T 13-09-2016 THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 PANTHER PTHR23115:SF175 400 598 3.4E-275 T 13-09-2016 THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 Pfam PF00009 Elongation factor Tu GTP binding domain 6 184 1.3E-51 T 13-09-2016 THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 SUPERFAMILY SSF54980 295 373 1.83E-18 T 13-09-2016 IPR009022 Elongation factor G, III-V domain THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 175 1.4E-18 T 13-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 Gene3D G3DSA:2.40.30.10 197 292 5.1E-21 T 13-09-2016 THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 PANTHER PTHR23115 7 376 3.4E-275 T 13-09-2016 THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 PRINTS PR00315 GTP-binding elongation factor signature 93 104 8.8E-14 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 PRINTS PR00315 GTP-binding elongation factor signature 129 138 8.8E-14 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 PRINTS PR00315 GTP-binding elongation factor signature 77 87 8.8E-14 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 PRINTS PR00315 GTP-binding elongation factor signature 9 22 8.8E-14 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 PRINTS PR00315 GTP-binding elongation factor signature 52 60 8.8E-14 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 Gene3D G3DSA:3.40.50.300 4 196 2.9E-59 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 Pfam PF00679 Elongation factor G C-terminus 402 487 6.3E-20 T 13-09-2016 IPR000640 Translation elongation factor EFG, V domain THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 Gene3D G3DSA:3.30.70.240 404 492 1.1E-20 T 13-09-2016 IPR000640 Translation elongation factor EFG, V domain THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 Pfam PF06421 GTP-binding protein LepA C-terminus 490 596 4.8E-50 T 13-09-2016 IPR013842 GTP-binding protein LepA, C-terminal THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 Hamap MF_00071 Elongation factor 4 [lepA]. 1 599 300.735 T 13-09-2016 IPR006297 Elongation factor 4 GO:0005525 THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 SUPERFAMILY SSF54980 403 496 1.87E-24 T 13-09-2016 IPR009022 Elongation factor G, III-V domain THL1_RS21310 86c0721cd56f2658699e3a5e597af21f 599 SUPERFAMILY SSF52540 3 236 4.09E-56 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25430 872b9641c6270ceac14aa4e5c9b0e9a6 123 PANTHER PTHR12789 39 123 7.5E-29 T 13-09-2016 THL1_RS25430 872b9641c6270ceac14aa4e5c9b0e9a6 123 PIRSF PIRSF037511 1 123 4.2E-46 T 13-09-2016 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 THL1_RS25430 872b9641c6270ceac14aa4e5c9b0e9a6 123 Gene3D G3DSA:3.30.780.10 44 123 1.8E-31 T 13-09-2016 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 THL1_RS25430 872b9641c6270ceac14aa4e5c9b0e9a6 123 SUPERFAMILY SSF55159 13 120 1.7E-28 T 13-09-2016 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 THL1_RS25430 872b9641c6270ceac14aa4e5c9b0e9a6 123 Pfam PF01253 Translation initiation factor SUI1 47 117 6.2E-17 T 13-09-2016 IPR001950 Translation initiation factor SUI1 GO:0003743|GO:0006413 THL1_RS25430 872b9641c6270ceac14aa4e5c9b0e9a6 123 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 14 123 2.8E-37 T 13-09-2016 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 THL1_RS24445 48c92ae99c790943771d6b80809b9f19 207 Gene3D G3DSA:3.40.50.150 3 205 1.1E-72 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS24445 48c92ae99c790943771d6b80809b9f19 207 Pfam PF01728 FtsJ-like methyltransferase 28 204 8.9E-55 T 13-09-2016 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 THL1_RS24445 48c92ae99c790943771d6b80809b9f19 207 PANTHER PTHR10920 2 206 2.6E-126 T 13-09-2016 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 THL1_RS24445 48c92ae99c790943771d6b80809b9f19 207 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 8 204 30.391 T 13-09-2016 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 THL1_RS24445 48c92ae99c790943771d6b80809b9f19 207 SUPERFAMILY SSF53335 27 205 5.19E-41 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS24445 48c92ae99c790943771d6b80809b9f19 207 PANTHER PTHR10920:SF20 2 206 2.6E-126 T 13-09-2016 THL1_RS24445 48c92ae99c790943771d6b80809b9f19 207 PIRSF PIRSF005461 1 207 1.5E-79 T 13-09-2016 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 KEGG: 00564+2.1.1.16 THL1_RS21630 2978ea78e5b9dc98e6dc2b42b8897ec2 260 Gene3D G3DSA:3.10.310.10 123 248 1.1E-45 T 13-09-2016 THL1_RS21630 2978ea78e5b9dc98e6dc2b42b8897ec2 260 Gene3D G3DSA:3.10.310.10 1 122 9.1E-47 T 13-09-2016 THL1_RS21630 2978ea78e5b9dc98e6dc2b42b8897ec2 260 SUPERFAMILY SSF54506 1 259 8.57E-86 T 13-09-2016 THL1_RS21630 2978ea78e5b9dc98e6dc2b42b8897ec2 260 PANTHER PTHR13774 1 260 5.0E-109 T 13-09-2016 THL1_RS21630 2978ea78e5b9dc98e6dc2b42b8897ec2 260 Pfam PF02567 Phenazine biosynthesis-like protein 8 256 2.2E-63 T 13-09-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- THL1_RS21630 2978ea78e5b9dc98e6dc2b42b8897ec2 260 PANTHER PTHR13774:SF17 1 260 5.0E-109 T 13-09-2016 THL1_RS21630 2978ea78e5b9dc98e6dc2b42b8897ec2 260 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 257 5.7E-44 T 13-09-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- THL1_RS21630 2978ea78e5b9dc98e6dc2b42b8897ec2 260 PIRSF PIRSF016184 1 260 1.9E-62 T 13-09-2016 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 KEGG: 00520+5.1.-.-|KEGG: 00960+5.1.-.- THL1_RS13860 e273e8252c4e6b45691c76b79807e1f9 819 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 151 819 1.8E-97 T 13-09-2016 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 THL1_RS13860 e273e8252c4e6b45691c76b79807e1f9 819 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 802 819 - T 13-09-2016 IPR010917 TonB-dependent receptor, conserved site THL1_RS13860 e273e8252c4e6b45691c76b79807e1f9 819 Gene3D G3DSA:2.170.130.10 150 264 1.6E-31 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS13860 e273e8252c4e6b45691c76b79807e1f9 819 Pfam PF07660 Secretin and TonB N terminus short domain 69 117 3.9E-9 T 13-09-2016 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 THL1_RS13860 e273e8252c4e6b45691c76b79807e1f9 819 Pfam PF07715 TonB-dependent Receptor Plug Domain 150 263 8.3E-21 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS13860 e273e8252c4e6b45691c76b79807e1f9 819 SMART SM00965 68 118 1.9E-11 T 13-09-2016 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 THL1_RS13860 e273e8252c4e6b45691c76b79807e1f9 819 Pfam PF00593 TonB dependent receptor 558 817 1.6E-32 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS13860 e273e8252c4e6b45691c76b79807e1f9 819 SUPERFAMILY SSF56935 134 819 2.02E-115 T 13-09-2016 THL1_RS13860 e273e8252c4e6b45691c76b79807e1f9 819 Gene3D G3DSA:2.40.170.20 265 819 1.7E-103 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS13860 e273e8252c4e6b45691c76b79807e1f9 819 PANTHER PTHR30442 4 819 2.5E-163 T 13-09-2016 THL1_RS24245 89fa9837a349769b9548dcb0f417eb3b 345 SUPERFAMILY SSF81345 6 342 3.14E-84 T 13-09-2016 IPR029022 ABC transporter, BtuC-like THL1_RS24245 89fa9837a349769b9548dcb0f417eb3b 345 Pfam PF01032 FecCD transport family 17 342 5.5E-92 T 13-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 THL1_RS24245 89fa9837a349769b9548dcb0f417eb3b 345 Gene3D G3DSA:1.10.3470.10 10 344 7.2E-110 T 13-09-2016 IPR029022 ABC transporter, BtuC-like THL1_RS24245 89fa9837a349769b9548dcb0f417eb3b 345 PANTHER PTHR30472:SF3 10 344 2.8E-144 T 13-09-2016 THL1_RS24245 89fa9837a349769b9548dcb0f417eb3b 345 PANTHER PTHR30472 10 344 2.8E-144 T 13-09-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 THL1_RS23780 195b4e6ca172d1cc48a97649b16fd8df 491 PANTHER PTHR11785 12 490 9.5E-213 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS23780 195b4e6ca172d1cc48a97649b16fd8df 491 PANTHER PTHR11785:SF204 12 490 9.5E-213 T 13-09-2016 THL1_RS23780 195b4e6ca172d1cc48a97649b16fd8df 491 ProSitePatterns PS00218 Amino acid permeases signature. 49 80 - T 13-09-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 THL1_RS23780 195b4e6ca172d1cc48a97649b16fd8df 491 PIRSF PIRSF006060 4 489 4.1E-79 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS23780 195b4e6ca172d1cc48a97649b16fd8df 491 Pfam PF00324 Amino acid permease 24 473 1.7E-134 T 13-09-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 THL1_RS22920 c226ecc9fc2ad409600971b128d2db1a 546 SMART SM00283 277 545 9.5E-47 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS22920 c226ecc9fc2ad409600971b128d2db1a 546 SMART SM00304 217 269 2.2E-11 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS22920 c226ecc9fc2ad409600971b128d2db1a 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 8 33 3.6E-20 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS22920 c226ecc9fc2ad409600971b128d2db1a 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 305 334 3.6E-20 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS22920 c226ecc9fc2ad409600971b128d2db1a 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 411 440 3.6E-20 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS22920 c226ecc9fc2ad409600971b128d2db1a 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 382 409 3.6E-20 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS22920 c226ecc9fc2ad409600971b128d2db1a 546 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 185 3.5E-22 T 13-09-2016 IPR024478 4HB MCP domain THL1_RS22920 c226ecc9fc2ad409600971b128d2db1a 546 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 351 544 3.3E-40 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS22920 c226ecc9fc2ad409600971b128d2db1a 546 Gene3D G3DSA:1.10.287.950 301 515 8.7E-46 T 13-09-2016 THL1_RS22920 c226ecc9fc2ad409600971b128d2db1a 546 SUPERFAMILY SSF58104 237 546 8.76E-61 T 13-09-2016 THL1_RS22920 c226ecc9fc2ad409600971b128d2db1a 546 PANTHER PTHR32089 111 546 1.6E-88 T 13-09-2016 THL1_RS22920 c226ecc9fc2ad409600971b128d2db1a 546 Pfam PF00672 HAMP domain 198 265 1.6E-12 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS15485 e5b2c4d7e62cb51762b886a1b171b579 207 SUPERFAMILY SSF46626 30 106 5.8E-17 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS15485 e5b2c4d7e62cb51762b886a1b171b579 207 SUPERFAMILY SSF46626 118 203 4.44E-11 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS15485 e5b2c4d7e62cb51762b886a1b171b579 207 Gene3D G3DSA:1.10.760.10 30 105 1.7E-20 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS15485 e5b2c4d7e62cb51762b886a1b171b579 207 PANTHER PTHR33751:SF3 29 203 4.9E-19 T 13-09-2016 THL1_RS15485 e5b2c4d7e62cb51762b886a1b171b579 207 Gene3D G3DSA:1.10.710.10 17 29 7.5E-4 T 13-09-2016 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674|UniPathway: UPA00653 THL1_RS15485 e5b2c4d7e62cb51762b886a1b171b579 207 Gene3D G3DSA:1.10.710.10 113 125 7.5E-4 T 13-09-2016 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674|UniPathway: UPA00653 THL1_RS15485 e5b2c4d7e62cb51762b886a1b171b579 207 PANTHER PTHR33751 29 203 4.9E-19 T 13-09-2016 THL1_RS15485 e5b2c4d7e62cb51762b886a1b171b579 207 PIRSF PIRSF000005 3 205 2.6E-32 T 13-09-2016 IPR024167 Cytochrome c4 GO:0005506|GO:0009055|GO:0020037|GO:0042597 THL1_RS15485 e5b2c4d7e62cb51762b886a1b171b579 207 Pfam PF00034 Cytochrome c 119 203 1.6E-5 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS15485 e5b2c4d7e62cb51762b886a1b171b579 207 Pfam PF00034 Cytochrome c 30 98 2.6E-5 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS15485 e5b2c4d7e62cb51762b886a1b171b579 207 Gene3D G3DSA:1.10.760.10 126 203 6.2E-13 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS13570 a5463bc5201f5127efb35f2c10a236a2 484 Pfam PF01425 Amidase 31 462 4.4E-87 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS13570 a5463bc5201f5127efb35f2c10a236a2 484 PANTHER PTHR11895:SF76 3 479 3.2E-224 T 13-09-2016 THL1_RS13570 a5463bc5201f5127efb35f2c10a236a2 484 SUPERFAMILY SSF75304 7 471 1.57E-126 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS13570 a5463bc5201f5127efb35f2c10a236a2 484 PANTHER PTHR11895 3 479 3.2E-224 T 13-09-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS13570 a5463bc5201f5127efb35f2c10a236a2 484 Gene3D G3DSA:3.90.1300.10 8 478 1.2E-121 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS09295 8c4eb9d775756c75ef1d65e36d6be5e4 274 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 262 3.7E-39 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS09295 8c4eb9d775756c75ef1d65e36d6be5e4 274 Gene3D G3DSA:3.40.190.10 21 146 6.9E-30 T 13-09-2016 THL1_RS09295 8c4eb9d775756c75ef1d65e36d6be5e4 274 PANTHER PTHR18966 35 262 2.4E-17 T 13-09-2016 THL1_RS09295 8c4eb9d775756c75ef1d65e36d6be5e4 274 SMART SM00062 37 266 1.8E-30 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS09295 8c4eb9d775756c75ef1d65e36d6be5e4 274 PANTHER PTHR18966:SF191 35 262 2.4E-17 T 13-09-2016 THL1_RS09295 8c4eb9d775756c75ef1d65e36d6be5e4 274 SUPERFAMILY SSF53850 7 264 1.29E-41 T 13-09-2016 THL1_RS09295 8c4eb9d775756c75ef1d65e36d6be5e4 274 Gene3D G3DSA:3.40.190.10 147 217 2.9E-13 T 13-09-2016 THL1_RS11410 cae40ca4aa991f7f3d30a22770a18260 296 Gene3D G3DSA:3.40.50.720 1 163 1.5E-61 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11410 cae40ca4aa991f7f3d30a22770a18260 296 SUPERFAMILY SSF51735 1 162 2.76E-44 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11410 cae40ca4aa991f7f3d30a22770a18260 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 291 7.5E-36 T 13-09-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 THL1_RS11410 cae40ca4aa991f7f3d30a22770a18260 296 Gene3D G3DSA:1.10.1040.10 164 294 3.1E-47 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS11410 cae40ca4aa991f7f3d30a22770a18260 296 SUPERFAMILY SSF48179 163 294 1.7E-40 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS11410 cae40ca4aa991f7f3d30a22770a18260 296 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 13-09-2016 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 THL1_RS11410 cae40ca4aa991f7f3d30a22770a18260 296 PIRSF PIRSF000103 1 296 6.3E-78 T 13-09-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 THL1_RS11410 cae40ca4aa991f7f3d30a22770a18260 296 PANTHER PTHR22981 1 296 7.0E-126 T 13-09-2016 THL1_RS11410 cae40ca4aa991f7f3d30a22770a18260 296 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 5 293 2.0E-130 T 13-09-2016 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|UniPathway: UPA00362 THL1_RS11410 cae40ca4aa991f7f3d30a22770a18260 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 162 7.8E-50 T 13-09-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 THL1_RS16510 b82386bf6803f8694ce4d2400826b212 561 SUPERFAMILY SSF54373 292 474 2.55E-45 T 13-09-2016 THL1_RS16510 b82386bf6803f8694ce4d2400826b212 561 Pfam PF05199 GMC oxidoreductase 388 524 3.4E-42 T 13-09-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 THL1_RS16510 b82386bf6803f8694ce4d2400826b212 561 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 83 106 - T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS16510 b82386bf6803f8694ce4d2400826b212 561 Pfam PF00732 GMC oxidoreductase 6 296 1.6E-87 T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS16510 b82386bf6803f8694ce4d2400826b212 561 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 255 269 - T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS16510 b82386bf6803f8694ce4d2400826b212 561 PANTHER PTHR11552 4 549 2.8E-212 T 13-09-2016 THL1_RS16510 b82386bf6803f8694ce4d2400826b212 561 PANTHER PTHR11552:SF51 4 549 2.8E-212 T 13-09-2016 THL1_RS16510 b82386bf6803f8694ce4d2400826b212 561 SUPERFAMILY SSF51905 2 289 9.62E-87 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS16510 b82386bf6803f8694ce4d2400826b212 561 SUPERFAMILY SSF51905 473 531 9.62E-87 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS16510 b82386bf6803f8694ce4d2400826b212 561 Gene3D G3DSA:3.50.50.60 2 127 3.2E-121 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS16510 b82386bf6803f8694ce4d2400826b212 561 Gene3D G3DSA:3.50.50.60 188 314 3.2E-121 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS16510 b82386bf6803f8694ce4d2400826b212 561 Gene3D G3DSA:3.50.50.60 467 531 3.2E-121 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS16510 b82386bf6803f8694ce4d2400826b212 561 PIRSF PIRSF000137 1 538 4.8E-147 T 13-09-2016 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|UniPathway: UPA00529 THL1_RS26320 da15d4af800d1b6f371d31e3941cbb68 354 PIRSF PIRSF019169 1 354 1.9E-124 T 13-09-2016 IPR005883 Type IV pilus assembly protein PilM THL1_RS26320 da15d4af800d1b6f371d31e3941cbb68 354 SUPERFAMILY SSF53067 13 178 2.52E-11 T 13-09-2016 THL1_RS26320 da15d4af800d1b6f371d31e3941cbb68 354 Pfam PF11104 Type IV pilus assembly protein PilM; 14 353 2.7E-139 T 13-09-2016 IPR005883 Type IV pilus assembly protein PilM THL1_RS26320 da15d4af800d1b6f371d31e3941cbb68 354 SMART SM00842 12 181 0.0011 T 13-09-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 THL1_RS26320 da15d4af800d1b6f371d31e3941cbb68 354 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 9 353 3.0E-143 T 13-09-2016 IPR005883 Type IV pilus assembly protein PilM THL1_RS26320 da15d4af800d1b6f371d31e3941cbb68 354 PANTHER PTHR32432 1 353 4.3E-94 T 13-09-2016 THL1_RS26320 da15d4af800d1b6f371d31e3941cbb68 354 Gene3D G3DSA:3.30.420.40 8 104 2.9E-6 T 13-09-2016 THL1_RS26320 da15d4af800d1b6f371d31e3941cbb68 354 PANTHER PTHR32432:SF3 1 353 4.3E-94 T 13-09-2016 THL1_RS26320 da15d4af800d1b6f371d31e3941cbb68 354 SUPERFAMILY SSF53067 192 352 1.15E-26 T 13-09-2016 THL1_RS26320 da15d4af800d1b6f371d31e3941cbb68 354 Gene3D G3DSA:3.30.420.40 196 315 2.7E-28 T 13-09-2016 THL1_RS00235 a34b6915187486b312073d75d3465b42 352 PANTHER PTHR11228:SF26 7 312 9.5E-101 T 13-09-2016 THL1_RS00235 a34b6915187486b312073d75d3465b42 352 SUPERFAMILY SSF102114 57 264 9.81E-9 T 13-09-2016 THL1_RS00235 a34b6915187486b312073d75d3465b42 352 Gene3D G3DSA:3.20.20.70 156 268 9.3E-7 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS00235 a34b6915187486b312073d75d3465b42 352 SMART SM00729 63 287 0.0064 T 13-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THL1_RS00235 a34b6915187486b312073d75d3465b42 352 PANTHER PTHR11228 7 312 9.5E-101 T 13-09-2016 THL1_RS00235 a34b6915187486b312073d75d3465b42 352 Pfam PF04055 Radical SAM superfamily 67 245 2.0E-11 T 13-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 THL1_RS25090 9903e551430d5653b8d3c123b2dcb34b 206 PANTHER PTHR30055:SF66 1 205 1.8E-37 T 13-09-2016 THL1_RS25090 9903e551430d5653b8d3c123b2dcb34b 206 SUPERFAMILY SSF46689 1 72 1.9E-19 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS25090 9903e551430d5653b8d3c123b2dcb34b 206 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 13-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site THL1_RS25090 9903e551430d5653b8d3c123b2dcb34b 206 Gene3D G3DSA:1.10.10.60 1 59 7.0E-23 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS25090 9903e551430d5653b8d3c123b2dcb34b 206 Gene3D G3DSA:1.10.357.10 60 202 2.1E-18 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS25090 9903e551430d5653b8d3c123b2dcb34b 206 Pfam PF08361 MAATS-type transcriptional repressor, C-terminal region 83 199 2.5E-11 T 13-09-2016 IPR013572 Transcription regulator MAATS, C-terminal GO:0003677 THL1_RS25090 9903e551430d5653b8d3c123b2dcb34b 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.2E-17 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS25090 9903e551430d5653b8d3c123b2dcb34b 206 PANTHER PTHR30055 1 205 1.8E-37 T 13-09-2016 THL1_RS25090 9903e551430d5653b8d3c123b2dcb34b 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 5.6E-12 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS25090 9903e551430d5653b8d3c123b2dcb34b 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 5.6E-12 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS25090 9903e551430d5653b8d3c123b2dcb34b 206 SUPERFAMILY SSF48498 83 202 1.25E-9 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS24970 b87da619cb6903a3a0e54da8996f2891 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 203 6.3E-12 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS24970 b87da619cb6903a3a0e54da8996f2891 213 PANTHER PTHR26402 3 212 9.0E-54 T 13-09-2016 THL1_RS24970 b87da619cb6903a3a0e54da8996f2891 213 PANTHER PTHR26402:SF458 3 212 9.0E-54 T 13-09-2016 THL1_RS24970 b87da619cb6903a3a0e54da8996f2891 213 Gene3D G3DSA:3.40.50.2300 2 121 4.7E-25 T 13-09-2016 THL1_RS24970 b87da619cb6903a3a0e54da8996f2891 213 Gene3D G3DSA:1.10.10.10 123 212 2.8E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS24970 b87da619cb6903a3a0e54da8996f2891 213 SUPERFAMILY SSF52172 2 124 3.56E-23 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS24970 b87da619cb6903a3a0e54da8996f2891 213 Pfam PF00072 Response regulator receiver domain 5 119 1.5E-21 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS24970 b87da619cb6903a3a0e54da8996f2891 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS24970 b87da619cb6903a3a0e54da8996f2891 213 SMART SM00448 3 119 8.0E-16 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS24970 b87da619cb6903a3a0e54da8996f2891 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 7.9E-7 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS24970 b87da619cb6903a3a0e54da8996f2891 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 7.9E-7 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS24970 b87da619cb6903a3a0e54da8996f2891 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 7.9E-7 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS24970 b87da619cb6903a3a0e54da8996f2891 213 SUPERFAMILY SSF46894 147 212 5.44E-16 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS24970 b87da619cb6903a3a0e54da8996f2891 213 SMART SM00421 150 207 1.7E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS04575 a3fef6f5673d4c0bb4a932a391967da9 534 Gene3D G3DSA:3.40.109.10 424 513 2.1E-8 T 13-09-2016 IPR000415 Nitroreductase-like GO:0016491 THL1_RS04575 a3fef6f5673d4c0bb4a932a391967da9 534 Pfam PF00881 Nitroreductase family 68 224 5.9E-8 T 13-09-2016 IPR029479 Nitroreductase THL1_RS04575 a3fef6f5673d4c0bb4a932a391967da9 534 SUPERFAMILY SSF55469 421 516 1.24E-8 T 13-09-2016 IPR000415 Nitroreductase-like GO:0016491 THL1_RS04575 a3fef6f5673d4c0bb4a932a391967da9 534 PANTHER PTHR23026 100 118 1.7E-74 T 13-09-2016 THL1_RS04575 a3fef6f5673d4c0bb4a932a391967da9 534 SUPERFAMILY SSF55469 70 116 4.19E-10 T 13-09-2016 IPR000415 Nitroreductase-like GO:0016491 THL1_RS04575 a3fef6f5673d4c0bb4a932a391967da9 534 SUPERFAMILY SSF55469 151 246 4.19E-10 T 13-09-2016 IPR000415 Nitroreductase-like GO:0016491 THL1_RS04575 a3fef6f5673d4c0bb4a932a391967da9 534 PANTHER PTHR23026:SF102 68 83 1.7E-74 T 13-09-2016 THL1_RS04575 a3fef6f5673d4c0bb4a932a391967da9 534 PANTHER PTHR23026:SF102 346 526 1.7E-74 T 13-09-2016 THL1_RS04575 a3fef6f5673d4c0bb4a932a391967da9 534 PANTHER PTHR23026 68 83 1.7E-74 T 13-09-2016 THL1_RS04575 a3fef6f5673d4c0bb4a932a391967da9 534 PANTHER PTHR23026 346 526 1.7E-74 T 13-09-2016 THL1_RS04575 a3fef6f5673d4c0bb4a932a391967da9 534 Gene3D G3DSA:3.40.109.10 70 224 2.2E-8 T 13-09-2016 IPR000415 Nitroreductase-like GO:0016491 THL1_RS04575 a3fef6f5673d4c0bb4a932a391967da9 534 PANTHER PTHR23026:SF102 100 118 1.7E-74 T 13-09-2016 THL1_RS01360 44682ba4b198422048d4ae45ee87fdaa 205 PANTHER PTHR12907 10 201 5.8E-61 T 13-09-2016 THL1_RS01360 44682ba4b198422048d4ae45ee87fdaa 205 PANTHER PTHR12907:SF14 10 201 5.8E-61 T 13-09-2016 THL1_RS01360 44682ba4b198422048d4ae45ee87fdaa 205 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 111 199 1.9E-19 T 13-09-2016 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 THL1_RS01360 44682ba4b198422048d4ae45ee87fdaa 205 SMART SM00702 20 199 4.3E-26 T 13-09-2016 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 THL1_RS04610 af9b76a7825558042d72e768fbdacbb5 364 Hamap MF_01011 tRNA/tmRNA (uracil-C(5))-methyltransferase [trmA]. 4 364 41.462 T 13-09-2016 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 THL1_RS04610 af9b76a7825558042d72e768fbdacbb5 364 PANTHER PTHR11061:SF25 1 364 2.4E-193 T 13-09-2016 THL1_RS04610 af9b76a7825558042d72e768fbdacbb5 364 PANTHER PTHR11061 1 364 2.4E-193 T 13-09-2016 THL1_RS04610 af9b76a7825558042d72e768fbdacbb5 364 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 297 326 - T 13-09-2016 IPR030390 RNA methyltransferase TrmA, active site THL1_RS04610 af9b76a7825558042d72e768fbdacbb5 364 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 11 364 1.0E-175 T 13-09-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 THL1_RS04610 af9b76a7825558042d72e768fbdacbb5 364 Gene3D G3DSA:3.40.50.150 154 363 3.0E-44 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS04610 af9b76a7825558042d72e768fbdacbb5 364 SUPERFAMILY SSF53335 9 363 1.06E-54 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS04610 af9b76a7825558042d72e768fbdacbb5 364 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 346 356 - T 13-09-2016 IPR030391 RNA methyltransferase TrmA, conserved site THL1_RS04610 af9b76a7825558042d72e768fbdacbb5 364 TIGRFAM TIGR02143 trmA_only: tRNA (uracil(54)-C(5))-methyltransferase 11 364 3.3E-176 T 13-09-2016 IPR011869 tRNA/tmRNA (uracil-C(5))-methyltransferase, TrmA GO:0006396|GO:0030697 THL1_RS10175 4ef56d55b8cd225084333e411b594554 323 Pfam PF03934 Type II secretion system (T2SS), protein K 29 302 9.8E-88 T 13-09-2016 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 THL1_RS10175 4ef56d55b8cd225084333e411b594554 323 PANTHER PTHR38831:SF1 1 309 1.4E-34 T 13-09-2016 THL1_RS10175 4ef56d55b8cd225084333e411b594554 323 Gene3D G3DSA:1.10.40.60 211 263 3.1E-7 T 13-09-2016 THL1_RS10175 4ef56d55b8cd225084333e411b594554 323 PIRSF PIRSF002786 1 311 3.8E-78 T 13-09-2016 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 THL1_RS10175 4ef56d55b8cd225084333e411b594554 323 SUPERFAMILY SSF54523 270 309 1.19E-15 T 13-09-2016 THL1_RS10175 4ef56d55b8cd225084333e411b594554 323 SUPERFAMILY SSF54523 37 104 1.19E-15 T 13-09-2016 THL1_RS10175 4ef56d55b8cd225084333e411b594554 323 SUPERFAMILY SSF158544 105 208 7.59E-32 T 13-09-2016 THL1_RS10175 4ef56d55b8cd225084333e411b594554 323 Gene3D G3DSA:3.30.1300.30 27 102 1.6E-13 T 13-09-2016 THL1_RS10175 4ef56d55b8cd225084333e411b594554 323 Gene3D G3DSA:3.30.1300.30 271 309 1.6E-13 T 13-09-2016 THL1_RS10175 4ef56d55b8cd225084333e411b594554 323 PANTHER PTHR38831 1 309 1.4E-34 T 13-09-2016 THL1_RS10175 4ef56d55b8cd225084333e411b594554 323 Gene3D G3DSA:1.10.40.60 104 209 5.7E-34 T 13-09-2016 THL1_RS28380 3e8f94f8da165aae97213cc58717cedb 402 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 256 373 8.2E-28 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS28380 3e8f94f8da165aae97213cc58717cedb 402 PANTHER PTHR13748 1 331 8.5E-188 T 13-09-2016 THL1_RS28380 3e8f94f8da165aae97213cc58717cedb 402 Gene3D G3DSA:3.40.50.300 3 229 1.2E-71 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28380 3e8f94f8da165aae97213cc58717cedb 402 PANTHER PTHR13748 347 387 8.5E-188 T 13-09-2016 THL1_RS28380 3e8f94f8da165aae97213cc58717cedb 402 Gene3D G3DSA:3.30.1220.10 243 373 3.4E-16 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS28380 3e8f94f8da165aae97213cc58717cedb 402 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 210 2.9E-55 T 13-09-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain THL1_RS28380 3e8f94f8da165aae97213cc58717cedb 402 PANTHER PTHR13748:SF4 1 331 8.5E-188 T 13-09-2016 THL1_RS28380 3e8f94f8da165aae97213cc58717cedb 402 SUPERFAMILY SSF52540 3 324 7.97E-42 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28380 3e8f94f8da165aae97213cc58717cedb 402 PANTHER PTHR13748:SF4 347 387 8.5E-188 T 13-09-2016 THL1_RS28380 3e8f94f8da165aae97213cc58717cedb 402 SMART SM00833 256 373 5.5E-44 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS11330 9f0ecb0de28dadb4d990c6c5c5cc86f3 265 SUPERFAMILY SSF54001 51 254 9.03E-41 T 13-09-2016 THL1_RS11330 9f0ecb0de28dadb4d990c6c5c5cc86f3 265 PANTHER PTHR33490 1 254 3.3E-119 T 13-09-2016 THL1_RS11330 9f0ecb0de28dadb4d990c6c5c5cc86f3 265 PANTHER PTHR33490:SF5 1 254 3.3E-119 T 13-09-2016 THL1_RS11330 9f0ecb0de28dadb4d990c6c5c5cc86f3 265 SMART SM00460 153 215 1.7E-16 T 13-09-2016 IPR002931 Transglutaminase-like THL1_RS11330 9f0ecb0de28dadb4d990c6c5c5cc86f3 265 Gene3D G3DSA:3.90.260.10 154 245 2.5E-11 T 13-09-2016 IPR002931 Transglutaminase-like THL1_RS11330 9f0ecb0de28dadb4d990c6c5c5cc86f3 265 Pfam PF01841 Transglutaminase-like superfamily 126 212 9.9E-21 T 13-09-2016 IPR002931 Transglutaminase-like THL1_RS11330 9f0ecb0de28dadb4d990c6c5c5cc86f3 265 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 3 79 4.7E-23 T 13-09-2016 IPR013589 Bacterial transglutaminase-like, N-terminal THL1_RS08555 97bf11734a5ccbb2d14aaa532f312195 254 PANTHER PTHR30043:SF1 6 252 1.1E-88 T 13-09-2016 THL1_RS08555 97bf11734a5ccbb2d14aaa532f312195 254 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 6 251 1.5E-73 T 13-09-2016 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 THL1_RS08555 97bf11734a5ccbb2d14aaa532f312195 254 PANTHER PTHR30043 6 252 1.1E-88 T 13-09-2016 THL1_RS08555 97bf11734a5ccbb2d14aaa532f312195 254 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 248 3.1E-14 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS08555 97bf11734a5ccbb2d14aaa532f312195 254 SUPERFAMILY SSF161098 59 241 5.49E-29 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS08555 97bf11734a5ccbb2d14aaa532f312195 254 Gene3D G3DSA:1.10.3720.10 58 251 1.1E-22 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS25550 02f5ebca96fe85965937b65752b3b8ce 286 PANTHER PTHR24220 47 286 3.5E-142 T 13-09-2016 THL1_RS25550 02f5ebca96fe85965937b65752b3b8ce 286 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 264 285 4.8E-8 T 13-09-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal THL1_RS25550 02f5ebca96fe85965937b65752b3b8ce 286 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 45 286 1.5E-116 T 13-09-2016 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD THL1_RS25550 02f5ebca96fe85965937b65752b3b8ce 286 SUPERFAMILY SSF52540 45 284 1.81E-54 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25550 02f5ebca96fe85965937b65752b3b8ce 286 PANTHER PTHR24220:SF366 47 286 3.5E-142 T 13-09-2016 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD THL1_RS25550 02f5ebca96fe85965937b65752b3b8ce 286 Pfam PF00005 ABC transporter 61 216 2.5E-27 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS25550 02f5ebca96fe85965937b65752b3b8ce 286 Gene3D G3DSA:3.40.50.300 44 283 1.2E-56 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS12750 c5c6b76b96cd6b640d0446a598542f2d 156 SUPERFAMILY SSF46785 5 64 4.83E-11 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12750 c5c6b76b96cd6b640d0446a598542f2d 156 SMART SM00344 6 111 4.5E-16 T 13-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 THL1_RS12750 c5c6b76b96cd6b640d0446a598542f2d 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 1.0E-11 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS12750 c5c6b76b96cd6b640d0446a598542f2d 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 1.0E-11 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS12750 c5c6b76b96cd6b640d0446a598542f2d 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 1.0E-11 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS12750 c5c6b76b96cd6b640d0446a598542f2d 156 SUPERFAMILY SSF54909 69 148 7.69E-11 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS12750 c5c6b76b96cd6b640d0446a598542f2d 156 Gene3D G3DSA:1.10.10.10 5 53 6.8E-15 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12750 c5c6b76b96cd6b640d0446a598542f2d 156 PANTHER PTHR30154:SF2 1 156 2.0E-26 T 13-09-2016 THL1_RS12750 c5c6b76b96cd6b640d0446a598542f2d 156 PANTHER PTHR30154 1 156 2.0E-26 T 13-09-2016 THL1_RS12750 c5c6b76b96cd6b640d0446a598542f2d 156 Pfam PF01037 Lrp/AsnC ligand binding domain 73 135 2.0E-7 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS12750 c5c6b76b96cd6b640d0446a598542f2d 156 Pfam PF13404 AsnC-type helix-turn-helix domain 6 47 2.9E-13 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS12750 c5c6b76b96cd6b640d0446a598542f2d 156 Gene3D G3DSA:3.30.70.920 69 136 4.4E-10 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS09390 c365df06330d22d10526b56d2d71bcd1 467 SUPERFAMILY SSF103473 8 201 2.22E-59 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS09390 c365df06330d22d10526b56d2d71bcd1 467 SUPERFAMILY SSF103473 254 465 2.22E-59 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS09390 c365df06330d22d10526b56d2d71bcd1 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 23 47 1.5E-7 T 13-09-2016 THL1_RS09390 c365df06330d22d10526b56d2d71bcd1 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 114 134 1.5E-7 T 13-09-2016 THL1_RS09390 c365df06330d22d10526b56d2d71bcd1 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 1.5E-7 T 13-09-2016 THL1_RS09390 c365df06330d22d10526b56d2d71bcd1 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 308 332 1.5E-7 T 13-09-2016 THL1_RS09390 c365df06330d22d10526b56d2d71bcd1 467 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 426 1.6E-75 T 13-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 THL1_RS09390 c365df06330d22d10526b56d2d71bcd1 467 PANTHER PTHR23501 19 467 1.2E-89 T 13-09-2016 THL1_RS09390 c365df06330d22d10526b56d2d71bcd1 467 Gene3D G3DSA:1.20.1250.20 268 465 9.5E-17 T 13-09-2016 THL1_RS09390 c365df06330d22d10526b56d2d71bcd1 467 Gene3D G3DSA:1.20.1250.20 18 200 5.7E-31 T 13-09-2016 THL1_RS09390 c365df06330d22d10526b56d2d71bcd1 467 Pfam PF07690 Major Facilitator Superfamily 24 415 9.7E-47 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 245 260 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 Gene3D G3DSA:3.40.50.300 155 331 2.7E-57 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 Pfam PF08448 PAS fold 25 116 9.2E-8 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 SUPERFAMILY SSF55785 24 115 9.42E-13 T 13-09-2016 IPR000014 PAS domain THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 PANTHER PTHR32071 1 472 3.1E-225 T 13-09-2016 THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 Gene3D G3DSA:1.10.8.60 332 404 3.4E-17 T 13-09-2016 THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 SMART SM00091 19 86 1.7E-4 T 13-09-2016 IPR000014 PAS domain THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 436 453 5.7E-8 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 453 473 5.7E-8 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 PANTHER PTHR32071:SF22 1 472 3.1E-225 T 13-09-2016 THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 SUPERFAMILY SSF52540 158 400 8.68E-64 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 371 380 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 182 195 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 Gene3D G3DSA:1.10.10.60 428 472 7.7E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 SMART SM00382 178 326 2.5E-9 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 Pfam PF02954 Bacterial regulatory protein, Fis family 430 469 1.5E-13 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 Pfam PF00158 Sigma-54 interaction domain 159 326 3.7E-64 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 SUPERFAMILY SSF46689 371 472 2.99E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS16975 7b4adf2049aaa184e7cd63133963b0a7 474 Gene3D G3DSA:3.30.450.20 23 111 2.2E-10 T 13-09-2016 THL1_RS21810 dc7fe2b6d0224d3a7d2d9b6feac7977b 375 Gene3D G3DSA:3.20.20.30 311 371 3.2E-85 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS21810 dc7fe2b6d0224d3a7d2d9b6feac7977b 375 Gene3D G3DSA:3.20.20.30 1 273 3.2E-85 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS21810 dc7fe2b6d0224d3a7d2d9b6feac7977b 375 PANTHER PTHR30137 20 284 1.3E-45 T 13-09-2016 THL1_RS21810 dc7fe2b6d0224d3a7d2d9b6feac7977b 375 PANTHER PTHR30137 304 373 1.3E-45 T 13-09-2016 THL1_RS21810 dc7fe2b6d0224d3a7d2d9b6feac7977b 375 SUPERFAMILY SSF51679 1 372 2.36E-73 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS21810 dc7fe2b6d0224d3a7d2d9b6feac7977b 375 Pfam PF00296 Luciferase-like monooxygenase 21 339 8.5E-44 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS24405 2b084428d0a976967441b759a0e75b12 152 Gene3D G3DSA:3.30.300.70 3 80 6.7E-33 T 13-09-2016 IPR028989 Ribosome maturation factor RimP, N-terminal THL1_RS24405 2b084428d0a976967441b759a0e75b12 152 PANTHER PTHR33867 1 152 1.2E-55 T 13-09-2016 THL1_RS24405 2b084428d0a976967441b759a0e75b12 152 SUPERFAMILY SSF74942 84 151 2.62E-17 T 13-09-2016 IPR028998 Ribosome maturation factor RimP, C-terminal THL1_RS24405 2b084428d0a976967441b759a0e75b12 152 PANTHER PTHR33867:SF1 1 152 1.2E-55 T 13-09-2016 THL1_RS24405 2b084428d0a976967441b759a0e75b12 152 SUPERFAMILY SSF75420 3 83 1.44E-26 T 13-09-2016 IPR028989 Ribosome maturation factor RimP, N-terminal THL1_RS24405 2b084428d0a976967441b759a0e75b12 152 Pfam PF02576 Putative ribosome maturation factor RimP 11 147 5.1E-50 T 13-09-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 THL1_RS24405 2b084428d0a976967441b759a0e75b12 152 Gene3D G3DSA:2.30.30.180 88 147 1.5E-12 T 13-09-2016 IPR028998 Ribosome maturation factor RimP, C-terminal THL1_RS24405 2b084428d0a976967441b759a0e75b12 152 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 6 151 25.279 T 13-09-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 THL1_RS21775 b0a570b12fa1c449c50a6ffb09d0fb30 522 Gene3D G3DSA:3.40.50.980 8 182 1.7E-35 T 13-09-2016 THL1_RS21775 b0a570b12fa1c449c50a6ffb09d0fb30 522 PANTHER PTHR24096 46 520 8.6E-169 T 13-09-2016 THL1_RS21775 b0a570b12fa1c449c50a6ffb09d0fb30 522 ProSitePatterns PS00455 Putative AMP-binding domain signature. 178 189 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS21775 b0a570b12fa1c449c50a6ffb09d0fb30 522 PANTHER PTHR24096:SF214 46 520 8.6E-169 T 13-09-2016 THL1_RS21775 b0a570b12fa1c449c50a6ffb09d0fb30 522 Pfam PF13193 AMP-binding enzyme C-terminal domain 436 511 2.8E-18 T 13-09-2016 IPR025110 AMP-binding enzyme C-terminal domain THL1_RS21775 b0a570b12fa1c449c50a6ffb09d0fb30 522 SUPERFAMILY SSF56801 8 521 5.49E-154 T 13-09-2016 THL1_RS21775 b0a570b12fa1c449c50a6ffb09d0fb30 522 Pfam PF00501 AMP-binding enzyme 18 427 4.1E-101 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS21775 b0a570b12fa1c449c50a6ffb09d0fb30 522 Gene3D G3DSA:2.30.38.10 345 418 7.8E-31 T 13-09-2016 THL1_RS21775 b0a570b12fa1c449c50a6ffb09d0fb30 522 Gene3D G3DSA:3.40.50.980 183 338 5.6E-39 T 13-09-2016 THL1_RS21775 b0a570b12fa1c449c50a6ffb09d0fb30 522 Gene3D G3DSA:3.30.300.30 422 520 3.9E-31 T 13-09-2016 THL1_RS15575 8d1fa529201680a3d6a3dd7e95cb4fd2 336 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 16 322 4.8E-123 T 13-09-2016 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 THL1_RS15575 8d1fa529201680a3d6a3dd7e95cb4fd2 336 PANTHER PTHR30238:SF0 14 334 3.6E-156 T 13-09-2016 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 THL1_RS15575 8d1fa529201680a3d6a3dd7e95cb4fd2 336 PANTHER PTHR30238 14 334 3.6E-156 T 13-09-2016 THL1_RS15575 8d1fa529201680a3d6a3dd7e95cb4fd2 336 Pfam PF03741 Integral membrane protein TerC family 82 291 4.5E-59 T 13-09-2016 IPR005496 Integral membrane protein TerC GO:0016021 THL1_RS10020 c607fa0380d21d739fb5ecefdc6a590e 214 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 210 44.245 T 13-09-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10020 c607fa0380d21d739fb5ecefdc6a590e 214 Gene3D G3DSA:3.20.19.10 1 201 3.7E-52 T 13-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THL1_RS10020 c607fa0380d21d739fb5ecefdc6a590e 214 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 196 1.5E-89 T 13-09-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10020 c607fa0380d21d739fb5ecefdc6a590e 214 PANTHER PTHR11670 1 208 3.5E-111 T 13-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10020 c607fa0380d21d739fb5ecefdc6a590e 214 PANTHER PTHR11670:SF27 1 208 3.5E-111 T 13-09-2016 THL1_RS10020 c607fa0380d21d739fb5ecefdc6a590e 214 Pfam PF00694 Aconitase C-terminal domain 1 132 6.2E-38 T 13-09-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10020 c607fa0380d21d739fb5ecefdc6a590e 214 SUPERFAMILY SSF52016 1 204 4.12E-63 T 13-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THL1_RS13750 85f0c30260e19b3f1fc923e014504206 372 PRINTS PR01270 Histone deacetylase superfamily signature 259 269 1.6E-14 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS13750 85f0c30260e19b3f1fc923e014504206 372 PRINTS PR01270 Histone deacetylase superfamily signature 174 189 1.6E-14 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS13750 85f0c30260e19b3f1fc923e014504206 372 PRINTS PR01270 Histone deacetylase superfamily signature 140 163 1.6E-14 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS13750 85f0c30260e19b3f1fc923e014504206 372 PANTHER PTHR10625 1 16 2.1E-97 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS13750 85f0c30260e19b3f1fc923e014504206 372 PANTHER PTHR10625 32 349 2.1E-97 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS13750 85f0c30260e19b3f1fc923e014504206 372 Gene3D G3DSA:3.40.800.20 5 345 9.2E-94 T 13-09-2016 IPR023801 Histone deacetylase domain THL1_RS13750 85f0c30260e19b3f1fc923e014504206 372 PANTHER PTHR10625:SF104 32 349 2.1E-97 T 13-09-2016 THL1_RS13750 85f0c30260e19b3f1fc923e014504206 372 PANTHER PTHR10625:SF104 1 16 2.1E-97 T 13-09-2016 THL1_RS13750 85f0c30260e19b3f1fc923e014504206 372 Pfam PF00850 Histone deacetylase domain 43 327 7.1E-77 T 13-09-2016 IPR023801 Histone deacetylase domain THL1_RS13750 85f0c30260e19b3f1fc923e014504206 372 SUPERFAMILY SSF52768 2 348 9.59E-102 T 13-09-2016 THL1_RS23525 363ee085c0224094729f07885c43bd4f 267 PANTHER PTHR31350:SF1 70 257 2.3E-29 T 13-09-2016 THL1_RS23525 363ee085c0224094729f07885c43bd4f 267 Pfam PF13369 Transglutaminase-like superfamily 58 183 5.0E-35 T 13-09-2016 IPR032698 Protein SirB1, N-terminal THL1_RS23525 363ee085c0224094729f07885c43bd4f 267 PANTHER PTHR31350 70 257 2.3E-29 T 13-09-2016 THL1_RS23525 363ee085c0224094729f07885c43bd4f 267 Gene3D G3DSA:1.25.40.10 176 262 1.6E-5 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS23525 363ee085c0224094729f07885c43bd4f 267 Pfam PF13371 Tetratricopeptide repeat 186 258 3.8E-12 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS16795 4a8450636b50d2f41479b025cd080b9a 118 PANTHER PTHR12589 1 118 3.8E-51 T 13-09-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein THL1_RS16795 4a8450636b50d2f41479b025cd080b9a 118 SUPERFAMILY SSF55620 2 117 1.28E-41 T 13-09-2016 THL1_RS16795 4a8450636b50d2f41479b025cd080b9a 118 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 2 94 1.0E-31 T 13-09-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein THL1_RS16795 4a8450636b50d2f41479b025cd080b9a 118 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 2 117 3.3E-36 T 13-09-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein THL1_RS16795 4a8450636b50d2f41479b025cd080b9a 118 Gene3D G3DSA:3.30.479.10 1 117 3.0E-41 T 13-09-2016 THL1_RS16795 4a8450636b50d2f41479b025cd080b9a 118 PIRSF PIRSF006113 1 118 6.2E-50 T 13-09-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein THL1_RS17955 bda87f8096917eb0ea4d38fb565842fd 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 3.4E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17955 bda87f8096917eb0ea4d38fb565842fd 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 3.4E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17955 bda87f8096917eb0ea4d38fb565842fd 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 136 152 3.4E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17955 bda87f8096917eb0ea4d38fb565842fd 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 3.4E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17955 bda87f8096917eb0ea4d38fb565842fd 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 3.4E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17955 bda87f8096917eb0ea4d38fb565842fd 264 Gene3D G3DSA:3.40.50.720 2 255 1.6E-63 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS17955 bda87f8096917eb0ea4d38fb565842fd 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 255 9.7E-85 T 13-09-2016 THL1_RS17955 bda87f8096917eb0ea4d38fb565842fd 264 SUPERFAMILY SSF51735 6 255 1.82E-62 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS17955 bda87f8096917eb0ea4d38fb565842fd 264 PANTHER PTHR24322:SF317 11 146 1.6E-57 T 13-09-2016 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 THL1_RS17955 bda87f8096917eb0ea4d38fb565842fd 264 PANTHER PTHR24322:SF317 162 194 1.6E-57 T 13-09-2016 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 THL1_RS17955 bda87f8096917eb0ea4d38fb565842fd 264 PIRSF PIRSF000094 1 263 2.2E-111 T 13-09-2016 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 THL1_RS17955 bda87f8096917eb0ea4d38fb565842fd 264 PANTHER PTHR24322 11 146 1.6E-57 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17955 bda87f8096917eb0ea4d38fb565842fd 264 PANTHER PTHR24322 162 194 1.6E-57 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17355 876fbaaa0122f2691bc5f64b8c36a313 386 Gene3D G3DSA:1.10.10.10 299 369 2.8E-6 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS17355 876fbaaa0122f2691bc5f64b8c36a313 386 Gene3D G3DSA:1.10.3290.10 26 298 1.5E-58 T 13-09-2016 IPR003812 Fido domain THL1_RS17355 876fbaaa0122f2691bc5f64b8c36a313 386 PANTHER PTHR13504 1 383 3.8E-197 T 13-09-2016 THL1_RS17355 876fbaaa0122f2691bc5f64b8c36a313 386 Pfam PF02661 Fic/DOC family 115 227 4.6E-15 T 13-09-2016 IPR003812 Fido domain THL1_RS17355 876fbaaa0122f2691bc5f64b8c36a313 386 PANTHER PTHR13504:SF33 1 383 3.8E-197 T 13-09-2016 THL1_RS17355 876fbaaa0122f2691bc5f64b8c36a313 386 Pfam PF13776 Domain of unknown function (DUF4172) 7 87 2.3E-29 T 13-09-2016 IPR025230 Domain of unknown function DUF4172 THL1_RS17355 876fbaaa0122f2691bc5f64b8c36a313 386 SUPERFAMILY SSF46785 274 370 1.76E-5 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS17355 876fbaaa0122f2691bc5f64b8c36a313 386 SUPERFAMILY SSF140931 100 297 4.19E-36 T 13-09-2016 IPR003812 Fido domain THL1_RS07945 15945d2f7ce1ad9b1f476350f59b90cc 162 Pfam PF03928 Haem-degrading 30 154 1.0E-28 T 13-09-2016 IPR005624 Haem-degrading THL1_RS07945 15945d2f7ce1ad9b1f476350f59b90cc 162 PANTHER PTHR34309 1 156 5.6E-31 T 13-09-2016 THL1_RS07945 15945d2f7ce1ad9b1f476350f59b90cc 162 PANTHER PTHR34309:SF1 1 156 5.6E-31 T 13-09-2016 THL1_RS07945 15945d2f7ce1ad9b1f476350f59b90cc 162 SUPERFAMILY SSF143744 23 156 2.35E-34 T 13-09-2016 THL1_RS22605 a89d8f7a2f41ac6f72d8020b816a6d59 450 SMART SM00228 211 280 2.3E-7 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS22605 a89d8f7a2f41ac6f72d8020b816a6d59 450 SMART SM00228 115 186 3.7E-5 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS22605 a89d8f7a2f41ac6f72d8020b816a6d59 450 PANTHER PTHR22939:SF78 205 450 5.5E-80 T 13-09-2016 THL1_RS22605 a89d8f7a2f41ac6f72d8020b816a6d59 450 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 223 276 2.8E-6 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS22605 a89d8f7a2f41ac6f72d8020b816a6d59 450 Gene3D G3DSA:2.30.42.10 95 187 3.8E-16 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS22605 a89d8f7a2f41ac6f72d8020b816a6d59 450 SUPERFAMILY SSF50156 87 180 4.6E-15 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS22605 a89d8f7a2f41ac6f72d8020b816a6d59 450 Gene3D G3DSA:2.30.42.10 221 292 1.3E-14 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS22605 a89d8f7a2f41ac6f72d8020b816a6d59 450 PANTHER PTHR22939 205 450 5.5E-80 T 13-09-2016 THL1_RS22605 a89d8f7a2f41ac6f72d8020b816a6d59 450 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 2 450 1.8E-125 T 13-09-2016 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 THL1_RS22605 a89d8f7a2f41ac6f72d8020b816a6d59 450 Pfam PF02163 Peptidase family M50 11 437 6.3E-82 T 13-09-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 THL1_RS22605 a89d8f7a2f41ac6f72d8020b816a6d59 450 SUPERFAMILY SSF50156 207 291 5.65E-15 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS25680 a6e3b4fa1e0f7271cbbda4478771fc6c 291 PANTHER PTHR24220:SF358 103 136 1.8E-112 T 13-09-2016 THL1_RS25680 a6e3b4fa1e0f7271cbbda4478771fc6c 291 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 262 284 2.4E-10 T 13-09-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal THL1_RS25680 a6e3b4fa1e0f7271cbbda4478771fc6c 291 PANTHER PTHR24220:SF358 8 72 1.8E-112 T 13-09-2016 THL1_RS25680 a6e3b4fa1e0f7271cbbda4478771fc6c 291 ProSitePatterns PS00211 ABC transporters family signature. 185 199 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS25680 a6e3b4fa1e0f7271cbbda4478771fc6c 291 SUPERFAMILY SSF52540 4 97 1.03E-59 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25680 a6e3b4fa1e0f7271cbbda4478771fc6c 291 SUPERFAMILY SSF52540 154 281 1.03E-59 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25680 a6e3b4fa1e0f7271cbbda4478771fc6c 291 Pfam PF00005 ABC transporter 22 212 1.1E-27 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS25680 a6e3b4fa1e0f7271cbbda4478771fc6c 291 PANTHER PTHR24220 103 136 1.8E-112 T 13-09-2016 THL1_RS25680 a6e3b4fa1e0f7271cbbda4478771fc6c 291 PANTHER PTHR24220:SF358 152 290 1.8E-112 T 13-09-2016 THL1_RS25680 a6e3b4fa1e0f7271cbbda4478771fc6c 291 PANTHER PTHR24220 152 290 1.8E-112 T 13-09-2016 THL1_RS25680 a6e3b4fa1e0f7271cbbda4478771fc6c 291 PANTHER PTHR24220 8 72 1.8E-112 T 13-09-2016 THL1_RS25680 a6e3b4fa1e0f7271cbbda4478771fc6c 291 SMART SM00382 31 262 1.3E-8 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS25680 a6e3b4fa1e0f7271cbbda4478771fc6c 291 Gene3D G3DSA:3.40.50.300 3 283 8.9E-65 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24825 4188401626989cb108546f8c532fcb9c 1905 Gene3D G3DSA:2.60.40.420 1249 1317 6.9E-7 T 13-09-2016 IPR008972 Cupredoxin THL1_RS24825 4188401626989cb108546f8c532fcb9c 1905 Gene3D G3DSA:2.60.40.420 426 522 8.5E-14 T 13-09-2016 IPR008972 Cupredoxin THL1_RS24825 4188401626989cb108546f8c532fcb9c 1905 Gene3D G3DSA:2.60.40.420 1164 1165 6.9E-7 T 13-09-2016 IPR008972 Cupredoxin THL1_RS24825 4188401626989cb108546f8c532fcb9c 1905 Gene3D G3DSA:2.60.40.420 1065 1099 6.9E-7 T 13-09-2016 IPR008972 Cupredoxin THL1_RS24825 4188401626989cb108546f8c532fcb9c 1905 Gene3D G3DSA:2.60.40.420 80 209 5.1E-6 T 13-09-2016 IPR008972 Cupredoxin THL1_RS24825 4188401626989cb108546f8c532fcb9c 1905 SUPERFAMILY SSF49503 1238 1305 2.37E-5 T 13-09-2016 IPR008972 Cupredoxin THL1_RS24825 4188401626989cb108546f8c532fcb9c 1905 SUPERFAMILY SSF49503 428 522 6.92E-17 T 13-09-2016 IPR008972 Cupredoxin THL1_RS24825 4188401626989cb108546f8c532fcb9c 1905 ProSitePatterns PS00080 Multicopper oxidases signature 2. 503 514 - T 13-09-2016 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 THL1_RS24825 4188401626989cb108546f8c532fcb9c 1905 Pfam PF07731 Multicopper oxidase 427 517 2.5E-4 T 13-09-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 SUPERFAMILY SSF52317 153 377 8.1E-61 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 Pfam PF00117 Glutamine amidotransferase class-I 197 372 3.6E-46 T 13-09-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 SMART SM01097 3 133 4.2E-91 T 13-09-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 PRINTS PR00096 Glutamine amidotransferase superfamily signature 236 245 5.3E-11 T 13-09-2016 THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 PRINTS PR00096 Glutamine amidotransferase superfamily signature 264 275 5.3E-11 T 13-09-2016 THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 PRINTS PR00096 Glutamine amidotransferase superfamily signature 349 362 5.3E-11 T 13-09-2016 THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 375 4.6E-142 T 13-09-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 264 280 3.5E-39 T 13-09-2016 THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 281 298 3.5E-39 T 13-09-2016 THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 306 317 3.5E-39 T 13-09-2016 THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 194 208 3.5E-39 T 13-09-2016 THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 233 247 3.5E-39 T 13-09-2016 THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 3 378 47.005 T 13-09-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 SUPERFAMILY SSF52021 4 143 1.7E-56 T 13-09-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 Gene3D G3DSA:3.40.50.880 154 376 3.9E-80 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 5 132 1.9E-51 T 13-09-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 Gene3D G3DSA:3.50.30.20 3 145 9.1E-61 T 13-09-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 PANTHER PTHR11405 190 378 5.1E-240 T 13-09-2016 THL1_RS24475 7ab069d28e4a13efadc46993d3759e6d 378 PANTHER PTHR11405 3 170 5.1E-240 T 13-09-2016 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 Hamap MF_01201 Alanine racemase. 1 357 35.91 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 PRINTS PR00992 Alanine racemase signature 266 281 2.4E-64 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 PRINTS PR00992 Alanine racemase signature 121 133 2.4E-64 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 PRINTS PR00992 Alanine racemase signature 61 79 2.4E-64 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 PRINTS PR00992 Alanine racemase signature 339 352 2.4E-64 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 PRINTS PR00992 Alanine racemase signature 26 42 2.4E-64 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 PRINTS PR00992 Alanine racemase signature 155 166 2.4E-64 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 PRINTS PR00992 Alanine racemase signature 287 304 2.4E-64 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 PRINTS PR00992 Alanine racemase signature 192 219 2.4E-64 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 PRINTS PR00992 Alanine racemase signature 249 264 2.4E-64 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 SUPERFAMILY SSF51419 8 234 1.3E-67 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 31 41 - T 13-09-2016 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 SMART SM01005 233 357 3.5E-76 T 13-09-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 TIGRFAM TIGR00492 alr: alanine racemase 4 357 6.3E-108 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 PANTHER PTHR30511 1 357 4.0E-149 T 13-09-2016 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 Gene3D G3DSA:3.20.20.10 10 212 1.1E-63 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 SUPERFAMILY SSF50621 227 357 5.93E-51 T 13-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 Pfam PF01168 Alanine racemase, N-terminal domain 8 219 3.2E-61 T 13-09-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 Gene3D G3DSA:2.40.37.10 213 357 2.2E-60 T 13-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 PANTHER PTHR30511:SF0 1 357 4.0E-149 T 13-09-2016 THL1_RS25775 b419ea669b6f7d2c992c39262bfbd92f 358 Pfam PF00842 Alanine racemase, C-terminal domain 233 356 2.9E-42 T 13-09-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS01170 f33518b019db87dbb6be09cc021ac97d 221 PANTHER PTHR30055 2 196 2.0E-58 T 13-09-2016 THL1_RS01170 f33518b019db87dbb6be09cc021ac97d 221 Gene3D G3DSA:1.10.357.10 3 188 2.4E-24 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS01170 f33518b019db87dbb6be09cc021ac97d 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 55 4.3E-11 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS01170 f33518b019db87dbb6be09cc021ac97d 221 PANTHER PTHR30055:SF30 2 196 2.0E-58 T 13-09-2016 THL1_RS01170 f33518b019db87dbb6be09cc021ac97d 221 SUPERFAMILY SSF46689 3 71 4.08E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01170 f33518b019db87dbb6be09cc021ac97d 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.3E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS01170 f33518b019db87dbb6be09cc021ac97d 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.3E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS01170 f33518b019db87dbb6be09cc021ac97d 221 Pfam PF13972 Bacterial transcriptional repressor 61 201 7.2E-44 T 13-09-2016 IPR025722 Bacterial transcriptional repressor TetR THL1_RS19970 7281f551f36f74162e581d733ba3427e 106 Pfam PF09634 Protein of unknown function (DUF2025) 1 105 8.9E-59 T 13-09-2016 IPR023117 PA1123-like domain THL1_RS19970 7281f551f36f74162e581d733ba3427e 106 SUPERFAMILY SSF160477 1 105 4.58E-51 T 13-09-2016 IPR023117 PA1123-like domain THL1_RS19970 7281f551f36f74162e581d733ba3427e 106 Gene3D G3DSA:3.90.1650.10 1 105 6.0E-54 T 13-09-2016 IPR023117 PA1123-like domain THL1_RS00800 4256afb576f7b538e7fcac6992dff8ac 283 PANTHER PTHR30201 1 278 3.2E-75 T 13-09-2016 THL1_RS00800 4256afb576f7b538e7fcac6992dff8ac 283 TIGRFAM TIGR03132 malonate_mdcB: triphosphoribosyl-dephospho-CoA synthase MdcB 16 279 7.9E-103 T 13-09-2016 IPR017555 Triphosphoribosyl-dephospho-CoA synthase GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 THL1_RS00800 4256afb576f7b538e7fcac6992dff8ac 283 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 18 278 5.0E-73 T 13-09-2016 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 THL1_RS00800 4256afb576f7b538e7fcac6992dff8ac 283 Hamap MF_01883 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase [mdcB]. 1 283 150.26 T 13-09-2016 IPR017555 Triphosphoribosyl-dephospho-CoA synthase GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 THL1_RS12490 31b9a63f1f5ea51b9e9027d72c322f7a 606 Gene3D G3DSA:1.10.150.20 550 604 6.9E-24 T 13-09-2016 THL1_RS12490 31b9a63f1f5ea51b9e9027d72c322f7a 606 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 382 537 1.6E-51 T 13-09-2016 IPR001162 UvrC family homology region THL1_RS12490 31b9a63f1f5ea51b9e9027d72c322f7a 606 SUPERFAMILY SSF46600 189 241 3.79E-12 T 13-09-2016 IPR001943 UVR domain GO:0005515 THL1_RS12490 31b9a63f1f5ea51b9e9027d72c322f7a 606 Gene3D G3DSA:3.40.1440.10 17 96 2.0E-7 T 13-09-2016 IPR027299 GIY-YIG domain THL1_RS12490 31b9a63f1f5ea51b9e9027d72c322f7a 606 Pfam PF01541 GIY-YIG catalytic domain 18 92 1.1E-10 T 13-09-2016 IPR000305 GIY-YIG nuclease superfamily THL1_RS12490 31b9a63f1f5ea51b9e9027d72c322f7a 606 Gene3D G3DSA:4.10.860.10 181 241 1.7E-18 T 13-09-2016 IPR001943 UVR domain GO:0005515 THL1_RS12490 31b9a63f1f5ea51b9e9027d72c322f7a 606 SUPERFAMILY SSF82771 16 99 1.57E-22 T 13-09-2016 IPR000305 GIY-YIG nuclease superfamily THL1_RS12490 31b9a63f1f5ea51b9e9027d72c322f7a 606 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 10 584 4.8E-185 T 13-09-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 THL1_RS12490 31b9a63f1f5ea51b9e9027d72c322f7a 606 Pfam PF02151 UvrB/uvrC motif 206 232 2.8E-8 T 13-09-2016 IPR001943 UVR domain GO:0005515 THL1_RS12490 31b9a63f1f5ea51b9e9027d72c322f7a 606 Hamap MF_00203 UvrABC system protein C [uvrC]. 3 602 29.571 T 13-09-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 THL1_RS12490 31b9a63f1f5ea51b9e9027d72c322f7a 606 SUPERFAMILY SSF47781 516 604 6.67E-24 T 13-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 THL1_RS12490 31b9a63f1f5ea51b9e9027d72c322f7a 606 PANTHER PTHR30562:SF1 8 603 4.2E-270 T 13-09-2016 THL1_RS12490 31b9a63f1f5ea51b9e9027d72c322f7a 606 PANTHER PTHR30562 8 603 4.2E-270 T 13-09-2016 THL1_RS12490 31b9a63f1f5ea51b9e9027d72c322f7a 606 SMART SM00465 16 97 1.4E-24 T 13-09-2016 IPR000305 GIY-YIG nuclease superfamily THL1_RS12490 31b9a63f1f5ea51b9e9027d72c322f7a 606 SMART SM00278 551 570 3.1 T 13-09-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THL1_RS12490 31b9a63f1f5ea51b9e9027d72c322f7a 606 SMART SM00278 583 602 1.3 T 13-09-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THL1_RS12490 31b9a63f1f5ea51b9e9027d72c322f7a 606 Pfam PF14520 Helix-hairpin-helix domain 552 603 8.5E-12 T 13-09-2016 THL1_RS18225 209bc9b43394cd9e24e904938bfa6530 286 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 121 245 1.3E-6 T 13-09-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 THL1_RS18225 209bc9b43394cd9e24e904938bfa6530 286 Gene3D G3DSA:1.10.1670.10 234 283 3.6E-16 T 13-09-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal THL1_RS18225 209bc9b43394cd9e24e904938bfa6530 286 PANTHER PTHR10242 62 285 2.2E-96 T 13-09-2016 THL1_RS18225 209bc9b43394cd9e24e904938bfa6530 286 SUPERFAMILY SSF48150 104 282 9.74E-46 T 13-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 THL1_RS18225 209bc9b43394cd9e24e904938bfa6530 286 SUPERFAMILY SSF55945 1 96 1.73E-22 T 13-09-2016 THL1_RS18225 209bc9b43394cd9e24e904938bfa6530 286 Gene3D G3DSA:1.10.340.30 116 233 4.5E-35 T 13-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 THL1_RS18225 209bc9b43394cd9e24e904938bfa6530 286 PANTHER PTHR10242:SF3 62 285 2.2E-96 T 13-09-2016 THL1_RS18225 209bc9b43394cd9e24e904938bfa6530 286 PANTHER PTHR10242:SF3 1 43 2.2E-96 T 13-09-2016 THL1_RS18225 209bc9b43394cd9e24e904938bfa6530 286 Pfam PF06029 AlkA N-terminal domain 1 115 1.1E-27 T 13-09-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal THL1_RS18225 209bc9b43394cd9e24e904938bfa6530 286 PANTHER PTHR10242 1 43 2.2E-96 T 13-09-2016 THL1_RS18225 209bc9b43394cd9e24e904938bfa6530 286 Gene3D G3DSA:3.30.310.20 1 115 1.3E-26 T 13-09-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal THL1_RS18225 209bc9b43394cd9e24e904938bfa6530 286 SMART SM01009 1 115 1.1E-34 T 13-09-2016 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal THL1_RS18225 209bc9b43394cd9e24e904938bfa6530 286 SMART SM00478 125 283 2.0E-16 T 13-09-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 THL1_RS21700 7c131af980a4c743cd6b40540e05a584 417 PANTHER PTHR11680 8 415 0.0 T 13-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 THL1_RS21700 7c131af980a4c743cd6b40540e05a584 417 Pfam PF00464 Serine hydroxymethyltransferase 8 385 3.1E-181 T 13-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 THL1_RS21700 7c131af980a4c743cd6b40540e05a584 417 PIRSF PIRSF000412 1 417 1.6E-166 T 13-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 THL1_RS21700 7c131af980a4c743cd6b40540e05a584 417 Gene3D G3DSA:3.40.640.10 37 283 2.1E-107 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS21700 7c131af980a4c743cd6b40540e05a584 417 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 416 53.347 T 13-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 THL1_RS21700 7c131af980a4c743cd6b40540e05a584 417 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 13-09-2016 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 THL1_RS21700 7c131af980a4c743cd6b40540e05a584 417 Gene3D G3DSA:3.90.1150.10 284 416 4.9E-54 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS21700 7c131af980a4c743cd6b40540e05a584 417 PANTHER PTHR11680:SF9 8 415 0.0 T 13-09-2016 THL1_RS21700 7c131af980a4c743cd6b40540e05a584 417 SUPERFAMILY SSF53383 5 415 1.08E-183 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS05535 8c50f7779574463103fa921af031c9f5 130 Gene3D G3DSA:3.30.230.10 5 130 4.9E-52 T 13-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THL1_RS05535 8c50f7779574463103fa921af031c9f5 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 13-09-2016 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 THL1_RS05535 8c50f7779574463103fa921af031c9f5 130 PANTHER PTHR21569 1 130 4.0E-72 T 13-09-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 THL1_RS05535 8c50f7779574463103fa921af031c9f5 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 4.0E-48 T 13-09-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 THL1_RS05535 8c50f7779574463103fa921af031c9f5 130 SUPERFAMILY SSF54211 6 130 1.63E-48 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS05535 8c50f7779574463103fa921af031c9f5 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 33.434 T 13-09-2016 IPR023035 Ribosomal protein S9, bacterial/plastid THL1_RS02000 089f76b78578cadc63b3a79339867348 287 PANTHER PTHR10520:SF7 6 279 1.3E-140 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS02000 089f76b78578cadc63b3a79339867348 287 Pfam PF00551 Formyl transferase 91 265 2.6E-36 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS02000 089f76b78578cadc63b3a79339867348 287 PANTHER PTHR10520 6 279 1.3E-140 T 13-09-2016 THL1_RS02000 089f76b78578cadc63b3a79339867348 287 Gene3D G3DSA:3.30.70.260 6 84 7.9E-12 T 13-09-2016 THL1_RS02000 089f76b78578cadc63b3a79339867348 287 SUPERFAMILY SSF55021 7 85 1.56E-8 T 13-09-2016 THL1_RS02000 089f76b78578cadc63b3a79339867348 287 Gene3D G3DSA:3.40.50.170 91 282 1.4E-53 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS02000 089f76b78578cadc63b3a79339867348 287 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 9 285 2.9E-89 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS02000 089f76b78578cadc63b3a79339867348 287 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 5 285 43.82 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS02000 089f76b78578cadc63b3a79339867348 287 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 10 36 4.9E-46 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS02000 089f76b78578cadc63b3a79339867348 287 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 42 54 4.9E-46 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS02000 089f76b78578cadc63b3a79339867348 287 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 113 140 4.9E-46 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS02000 089f76b78578cadc63b3a79339867348 287 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 237 259 4.9E-46 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS02000 089f76b78578cadc63b3a79339867348 287 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 259 284 4.9E-46 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS02000 089f76b78578cadc63b3a79339867348 287 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 91 113 4.9E-46 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS02000 089f76b78578cadc63b3a79339867348 287 PIRSF PIRSF036480 5 286 2.0E-100 T 13-09-2016 THL1_RS02000 089f76b78578cadc63b3a79339867348 287 SUPERFAMILY SSF53328 91 286 1.31E-59 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS07255 a953dcaf9e0548941bee6ddd95f75852 315 SUPERFAMILY SSF161098 41 303 1.21E-51 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07255 a953dcaf9e0548941bee6ddd95f75852 315 PANTHER PTHR30193:SF8 23 315 1.1E-85 T 13-09-2016 THL1_RS07255 a953dcaf9e0548941bee6ddd95f75852 315 Gene3D G3DSA:1.10.3720.10 40 300 1.6E-47 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07255 a953dcaf9e0548941bee6ddd95f75852 315 PANTHER PTHR30193 23 315 1.1E-85 T 13-09-2016 THL1_RS07255 a953dcaf9e0548941bee6ddd95f75852 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 300 7.0E-8 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS23120 19ff96f574ebb3c8928f0d856027bfb7 174 Gene3D G3DSA:2.160.10.10 5 167 3.4E-49 T 13-09-2016 THL1_RS23120 19ff96f574ebb3c8928f0d856027bfb7 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 120 7.5E-9 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS23120 19ff96f574ebb3c8928f0d856027bfb7 174 SUPERFAMILY SSF51161 8 169 5.68E-47 T 13-09-2016 IPR011004 Trimeric LpxA-like THL1_RS23120 19ff96f574ebb3c8928f0d856027bfb7 174 PANTHER PTHR13061 13 174 9.8E-74 T 13-09-2016 THL1_RS13855 e4ffad9475dced941fe7aae15a227c0c 323 PIRSF PIRSF018266 2 322 9.6E-87 T 13-09-2016 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component THL1_RS13855 e4ffad9475dced941fe7aae15a227c0c 323 PANTHER PTHR30273 5 320 2.6E-67 T 13-09-2016 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component THL1_RS13855 e4ffad9475dced941fe7aae15a227c0c 323 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 82 107 0.001 T 13-09-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THL1_RS13855 e4ffad9475dced941fe7aae15a227c0c 323 Pfam PF16220 Domain of unknown function (DUF4880) 13 55 3.4E-10 T 13-09-2016 IPR032623 FecR, N-terminal THL1_RS13855 e4ffad9475dced941fe7aae15a227c0c 323 PANTHER PTHR30273:SF2 5 320 2.6E-67 T 13-09-2016 THL1_RS13855 e4ffad9475dced941fe7aae15a227c0c 323 Pfam PF04773 FecR protein 116 207 2.8E-22 T 13-09-2016 IPR006860 FecR protein THL1_RS24290 226d3f88b3e8aa761893836adc2c5477 475 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 360 369 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS24290 226d3f88b3e8aa761893836adc2c5477 475 SMART SM00448 2 109 8.6E-31 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS24290 226d3f88b3e8aa761893836adc2c5477 475 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 171 184 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS24290 226d3f88b3e8aa761893836adc2c5477 475 PANTHER PTHR32071:SF18 1 475 3.9E-224 T 13-09-2016 THL1_RS24290 226d3f88b3e8aa761893836adc2c5477 475 SMART SM00382 167 332 1.4E-10 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS24290 226d3f88b3e8aa761893836adc2c5477 475 PANTHER PTHR32071 1 475 3.9E-224 T 13-09-2016 THL1_RS24290 226d3f88b3e8aa761893836adc2c5477 475 Pfam PF00158 Sigma-54 interaction domain 147 313 5.5E-73 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS24290 226d3f88b3e8aa761893836adc2c5477 475 Gene3D G3DSA:3.40.50.2300 1 119 1.1E-30 T 13-09-2016 THL1_RS24290 226d3f88b3e8aa761893836adc2c5477 475 Gene3D G3DSA:3.40.50.300 146 319 6.1E-61 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24290 226d3f88b3e8aa761893836adc2c5477 475 SUPERFAMILY SSF52540 146 388 6.56E-73 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24290 226d3f88b3e8aa761893836adc2c5477 475 Pfam PF00072 Response regulator receiver domain 4 109 6.9E-22 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS24290 226d3f88b3e8aa761893836adc2c5477 475 Gene3D G3DSA:1.10.8.60 320 389 4.9E-23 T 13-09-2016 THL1_RS24290 226d3f88b3e8aa761893836adc2c5477 475 SUPERFAMILY SSF52172 1 192 8.4E-40 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS24290 226d3f88b3e8aa761893836adc2c5477 475 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 233 248 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS08920 6048ccf4b119c72769cc01510878adf1 225 PANTHER PTHR26402:SF600 1 223 2.5E-116 T 13-09-2016 THL1_RS08920 6048ccf4b119c72769cc01510878adf1 225 Pfam PF00072 Response regulator receiver domain 4 112 1.2E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS08920 6048ccf4b119c72769cc01510878adf1 225 SMART SM00448 1 112 4.7E-40 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS08920 6048ccf4b119c72769cc01510878adf1 225 SUPERFAMILY SSF52172 1 177 5.27E-39 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS08920 6048ccf4b119c72769cc01510878adf1 225 Gene3D G3DSA:1.10.10.10 125 221 2.5E-28 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08920 6048ccf4b119c72769cc01510878adf1 225 Gene3D G3DSA:3.40.50.2300 1 120 5.2E-35 T 13-09-2016 THL1_RS08920 6048ccf4b119c72769cc01510878adf1 225 PANTHER PTHR26402 1 223 2.5E-116 T 13-09-2016 THL1_RS08920 6048ccf4b119c72769cc01510878adf1 225 SMART SM00862 145 220 1.6E-24 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS08920 6048ccf4b119c72769cc01510878adf1 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 220 3.4E-23 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS10570 46b886f9cb6369b16d7ee2d0f701cb58 267 SUPERFAMILY SSF50800 2 60 1.26E-20 T 13-09-2016 IPR011037 Pyruvate kinase-like, insert domain THL1_RS10570 46b886f9cb6369b16d7ee2d0f701cb58 267 SUPERFAMILY SSF50800 151 266 1.26E-20 T 13-09-2016 IPR011037 Pyruvate kinase-like, insert domain THL1_RS10570 46b886f9cb6369b16d7ee2d0f701cb58 267 SUPERFAMILY SSF141673 4 132 2.35E-29 T 13-09-2016 THL1_RS10570 46b886f9cb6369b16d7ee2d0f701cb58 267 Pfam PF03473 MOSC domain 141 264 9.6E-32 T 13-09-2016 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 THL1_RS10570 46b886f9cb6369b16d7ee2d0f701cb58 267 Pfam PF03476 MOSC N-terminal beta barrel domain 1 118 8.3E-26 T 13-09-2016 IPR005303 MOSC, N-terminal beta barrel THL1_RS10570 46b886f9cb6369b16d7ee2d0f701cb58 267 PANTHER PTHR14237 3 267 5.7E-84 T 13-09-2016 THL1_RS19650 ef23d99f0c70079af8474262ba417734 480 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 236 460 1.3E-55 T 13-09-2016 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 THL1_RS19650 ef23d99f0c70079af8474262ba417734 480 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 9 105 5.4E-22 T 13-09-2016 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 THL1_RS19650 ef23d99f0c70079af8474262ba417734 480 Pfam PF07196 Flagellin hook IN motif 124 182 4.7E-10 T 13-09-2016 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 THL1_RS19650 ef23d99f0c70079af8474262ba417734 480 PANTHER PTHR30288 1 475 1.4E-90 T 13-09-2016 THL1_RS19650 ef23d99f0c70079af8474262ba417734 480 PANTHER PTHR30288:SF0 1 475 1.4E-90 T 13-09-2016 THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 PANTHER PTHR26402:SF437 330 335 4.3E-19 T 13-09-2016 THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 SMART SM00028 551 584 13.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 SMART SM00028 719 752 24.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 SMART SM00028 430 463 350.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 SMART SM00421 785 842 7.9E-23 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 PANTHER PTHR26402:SF437 758 848 4.3E-19 T 13-09-2016 THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 PANTHER PTHR26402 758 848 4.3E-19 T 13-09-2016 THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 SUPERFAMILY SSF48452 552 664 5.08E-6 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 SUPERFAMILY SSF46894 779 847 2.35E-20 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 SUPERFAMILY SSF48452 426 753 2.05E-6 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 ProSitePatterns PS00622 LuxR-type HTH domain signature. 802 829 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 PANTHER PTHR26402 330 335 4.3E-19 T 13-09-2016 THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 788 802 2.3E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 802 818 2.3E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 818 830 2.3E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 Gene3D G3DSA:1.10.10.10 785 847 8.0E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 Gene3D G3DSA:1.25.40.10 419 777 9.9E-29 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS23530 3365a14628e2421ace2523d42bd9ce67 848 Pfam PF00196 Bacterial regulatory proteins, luxR family 787 842 1.1E-17 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS00720 7e3f9c1fba1b194ac3864911114b3a3b 395 PANTHER PTHR11351:SF33 8 374 1.8E-206 T 13-09-2016 THL1_RS00720 7e3f9c1fba1b194ac3864911114b3a3b 395 PANTHER PTHR11351 8 374 1.8E-206 T 13-09-2016 THL1_RS00720 7e3f9c1fba1b194ac3864911114b3a3b 395 Pfam PF00487 Fatty acid desaturase 11 214 9.8E-12 T 13-09-2016 IPR005804 Fatty acid desaturase domain GO:0006629 THL1_RS00720 7e3f9c1fba1b194ac3864911114b3a3b 395 Pfam PF01610 Transposase 286 387 4.7E-9 T 13-09-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain THL1_RS20915 3492ae16703a807fb7865351629728b1 256 Gene3D G3DSA:3.90.226.10 2 254 2.1E-81 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20915 3492ae16703a807fb7865351629728b1 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 255 1.5E-62 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS20915 3492ae16703a807fb7865351629728b1 256 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 97 117 - T 13-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THL1_RS20915 3492ae16703a807fb7865351629728b1 256 PANTHER PTHR11941 5 253 1.8E-87 T 13-09-2016 THL1_RS20915 3492ae16703a807fb7865351629728b1 256 PANTHER PTHR11941:SF54 5 253 1.8E-87 T 13-09-2016 THL1_RS20915 3492ae16703a807fb7865351629728b1 256 SUPERFAMILY SSF52096 2 255 1.89E-80 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS26590 1a556d14f47c4b2b7bb480fe99396c58 549 Pfam PF13188 PAS domain 249 281 1.6E-4 T 13-09-2016 IPR000014 PAS domain THL1_RS26590 1a556d14f47c4b2b7bb480fe99396c58 549 Pfam PF00990 Diguanylate cyclase, GGDEF domain 382 539 2.2E-44 T 13-09-2016 IPR000160 GGDEF domain THL1_RS26590 1a556d14f47c4b2b7bb480fe99396c58 549 PANTHER PTHR10799:SF774 415 539 2.0E-26 T 13-09-2016 THL1_RS26590 1a556d14f47c4b2b7bb480fe99396c58 549 Pfam PF16927 N-terminal 7TM region of histidine kinase 16 243 1.7E-50 T 13-09-2016 IPR031621 Histidine kinase, N-terminal 7TM region THL1_RS26590 1a556d14f47c4b2b7bb480fe99396c58 549 Gene3D G3DSA:3.30.70.270 384 545 9.1E-55 T 13-09-2016 THL1_RS26590 1a556d14f47c4b2b7bb480fe99396c58 549 SMART SM00267 371 543 4.2E-58 T 13-09-2016 IPR000160 GGDEF domain THL1_RS26590 1a556d14f47c4b2b7bb480fe99396c58 549 Gene3D G3DSA:3.30.450.20 248 280 6.3E-5 T 13-09-2016 THL1_RS26590 1a556d14f47c4b2b7bb480fe99396c58 549 PANTHER PTHR10799 257 378 2.0E-26 T 13-09-2016 THL1_RS26590 1a556d14f47c4b2b7bb480fe99396c58 549 PANTHER PTHR10799 415 539 2.0E-26 T 13-09-2016 THL1_RS26590 1a556d14f47c4b2b7bb480fe99396c58 549 PANTHER PTHR10799:SF774 257 378 2.0E-26 T 13-09-2016 THL1_RS26590 1a556d14f47c4b2b7bb480fe99396c58 549 SUPERFAMILY SSF55073 387 543 1.96E-49 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS26590 1a556d14f47c4b2b7bb480fe99396c58 549 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 378 541 7.1E-49 T 13-09-2016 IPR000160 GGDEF domain THL1_RS25180 7ef8639c4ebcc848485ba1316754301e 284 Gene3D G3DSA:3.10.129.10 64 160 4.2E-6 T 13-09-2016 IPR029069 HotDog domain THL1_RS25180 7ef8639c4ebcc848485ba1316754301e 284 PRINTS PR01483 Fatty acid synthase signature 181 203 6.8E-6 T 13-09-2016 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 THL1_RS25180 7ef8639c4ebcc848485ba1316754301e 284 PRINTS PR01483 Fatty acid synthase signature 203 224 6.8E-6 T 13-09-2016 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 THL1_RS25180 7ef8639c4ebcc848485ba1316754301e 284 SUPERFAMILY SSF54637 45 160 1.31E-7 T 13-09-2016 IPR029069 HotDog domain THL1_RS25180 7ef8639c4ebcc848485ba1316754301e 284 Gene3D G3DSA:3.10.129.10 176 266 5.5E-22 T 13-09-2016 IPR029069 HotDog domain THL1_RS25180 7ef8639c4ebcc848485ba1316754301e 284 Pfam PF01575 MaoC like domain 185 256 4.8E-13 T 13-09-2016 IPR002539 MaoC-like domain THL1_RS25180 7ef8639c4ebcc848485ba1316754301e 284 SUPERFAMILY SSF54637 172 259 2.5E-19 T 13-09-2016 IPR029069 HotDog domain THL1_RS25180 7ef8639c4ebcc848485ba1316754301e 284 PANTHER PTHR13078 1 283 1.2E-135 T 13-09-2016 THL1_RS25180 7ef8639c4ebcc848485ba1316754301e 284 PANTHER PTHR13078:SF54 1 283 1.2E-135 T 13-09-2016 THL1_RS24535 7f2ea9ef4f973be5280559eb9207c35c 561 PANTHER PTHR30003:SF6 2 561 0.0 T 13-09-2016 THL1_RS24535 7f2ea9ef4f973be5280559eb9207c35c 561 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 6 553 3.0E-222 T 13-09-2016 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 THL1_RS24535 7f2ea9ef4f973be5280559eb9207c35c 561 Pfam PF02652 L-lactate permease 16 549 2.0E-206 T 13-09-2016 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 THL1_RS24535 7f2ea9ef4f973be5280559eb9207c35c 561 PANTHER PTHR30003 2 561 0.0 T 13-09-2016 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 THL1_RS06190 c42416713f83ab857f296a286b62dad3 454 SUPERFAMILY SSF49503 39 162 1.05E-36 T 13-09-2016 IPR008972 Cupredoxin THL1_RS06190 c42416713f83ab857f296a286b62dad3 454 Gene3D G3DSA:2.60.40.420 156 278 1.7E-16 T 13-09-2016 IPR008972 Cupredoxin THL1_RS06190 c42416713f83ab857f296a286b62dad3 454 Pfam PF07731 Multicopper oxidase 349 453 8.4E-26 T 13-09-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 THL1_RS06190 c42416713f83ab857f296a286b62dad3 454 PANTHER PTHR11709 54 453 2.6E-89 T 13-09-2016 THL1_RS06190 c42416713f83ab857f296a286b62dad3 454 Gene3D G3DSA:2.60.40.420 309 453 7.7E-31 T 13-09-2016 IPR008972 Cupredoxin THL1_RS06190 c42416713f83ab857f296a286b62dad3 454 Gene3D G3DSA:2.60.40.420 34 155 9.0E-35 T 13-09-2016 IPR008972 Cupredoxin THL1_RS06190 c42416713f83ab857f296a286b62dad3 454 Pfam PF07732 Multicopper oxidase 55 159 8.2E-34 T 13-09-2016 IPR011707 Multicopper oxidase, type 3 GO:0005507 THL1_RS06190 c42416713f83ab857f296a286b62dad3 454 SUPERFAMILY SSF49503 310 453 3.32E-33 T 13-09-2016 IPR008972 Cupredoxin THL1_RS06190 c42416713f83ab857f296a286b62dad3 454 SUPERFAMILY SSF49503 162 279 3.9E-16 T 13-09-2016 IPR008972 Cupredoxin THL1_RS06190 c42416713f83ab857f296a286b62dad3 454 PANTHER PTHR11709:SF33 54 453 2.6E-89 T 13-09-2016 THL1_RS06190 c42416713f83ab857f296a286b62dad3 454 ProSitePatterns PS00080 Multicopper oxidases signature 2. 436 447 - T 13-09-2016 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 Gene3D G3DSA:1.20.1580.10 406 476 9.7E-54 T 13-09-2016 THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 Gene3D G3DSA:1.20.1580.10 91 129 9.7E-54 T 13-09-2016 THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 Gene3D G3DSA:1.20.1580.10 251 284 9.7E-54 T 13-09-2016 THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 Gene3D G3DSA:3.40.50.300 600 673 1.1E-60 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 Gene3D G3DSA:3.40.50.300 477 597 9.1E-57 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 Gene3D G3DSA:3.40.50.300 820 940 1.1E-60 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 Gene3D G3DSA:3.40.50.300 3 89 9.1E-57 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 Gene3D G3DSA:3.30.1490.20 130 153 4.8E-29 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 Gene3D G3DSA:3.30.1490.20 200 241 4.8E-29 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 Gene3D G3DSA:1.20.1580.10 693 819 1.1E-53 T 13-09-2016 THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 ProSitePatterns PS00211 ABC transporters family signature. 829 843 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 ProSitePatterns PS00211 ABC transporters family signature. 486 500 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 PANTHER PTHR32282 2 944 0.0 T 13-09-2016 THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 SUPERFAMILY SSF52540 7 204 9.52E-47 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 SUPERFAMILY SSF52540 456 568 9.52E-47 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 PANTHER PTHR32282:SF2 2 944 0.0 T 13-09-2016 THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 SUPERFAMILY SSF52540 614 909 2.47E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 Gene3D G3DSA:1.10.8.280 286 405 1.0E-40 T 13-09-2016 THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 939 22.841 T 13-09-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 THL1_RS03665 c0ec494d4f22ece3e860d35d818019c4 944 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 3 924 0.0 T 13-09-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 THL1_RS07710 c5a2474fc8837408f2a163dbdfa282cc 387 Pfam PF13458 Periplasmic binding protein 25 360 8.4E-65 T 13-09-2016 IPR028081 Leucine-binding protein domain THL1_RS07710 c5a2474fc8837408f2a163dbdfa282cc 387 Gene3D G3DSA:3.40.50.2300 149 294 3.7E-24 T 13-09-2016 THL1_RS07710 c5a2474fc8837408f2a163dbdfa282cc 387 SUPERFAMILY SSF53822 25 376 1.95E-74 T 13-09-2016 IPR028082 Periplasmic binding protein-like I THL1_RS07710 c5a2474fc8837408f2a163dbdfa282cc 387 Gene3D G3DSA:3.40.50.2300 295 349 2.4E-31 T 13-09-2016 THL1_RS07710 c5a2474fc8837408f2a163dbdfa282cc 387 Gene3D G3DSA:3.40.50.2300 21 147 2.4E-31 T 13-09-2016 THL1_RS07710 c5a2474fc8837408f2a163dbdfa282cc 387 PANTHER PTHR30483 1 350 1.4E-88 T 13-09-2016 THL1_RS07710 c5a2474fc8837408f2a163dbdfa282cc 387 PANTHER PTHR30483:SF13 1 350 1.4E-88 T 13-09-2016 THL1_RS19775 0f0986aed4177c8b90327ebc6394ca6a 697 Gene3D G3DSA:3.30.1490.20 482 525 7.0E-4 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS19775 0f0986aed4177c8b90327ebc6394ca6a 697 Gene3D G3DSA:3.40.50.720 1 125 1.2E-19 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS19775 0f0986aed4177c8b90327ebc6394ca6a 697 PANTHER PTHR33303:SF3 456 694 1.2E-212 T 13-09-2016 THL1_RS19775 0f0986aed4177c8b90327ebc6394ca6a 697 SUPERFAMILY SSF52210 292 455 2.35E-21 T 13-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 THL1_RS19775 0f0986aed4177c8b90327ebc6394ca6a 697 SUPERFAMILY SSF51735 2 133 5.44E-23 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS19775 0f0986aed4177c8b90327ebc6394ca6a 697 Gene3D G3DSA:3.40.50.261 126 285 2.0E-13 T 13-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 THL1_RS19775 0f0986aed4177c8b90327ebc6394ca6a 697 PANTHER PTHR33303 3 435 1.2E-212 T 13-09-2016 THL1_RS19775 0f0986aed4177c8b90327ebc6394ca6a 697 PANTHER PTHR33303 456 694 1.2E-212 T 13-09-2016 THL1_RS19775 0f0986aed4177c8b90327ebc6394ca6a 697 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 152 285 8.9E-34 T 13-09-2016 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain THL1_RS19775 0f0986aed4177c8b90327ebc6394ca6a 697 Pfam PF13380 CoA binding domain 25 130 2.0E-12 T 13-09-2016 IPR003781 CoA-binding GO:0048037 THL1_RS19775 0f0986aed4177c8b90327ebc6394ca6a 697 PANTHER PTHR33303:SF3 3 435 1.2E-212 T 13-09-2016 THL1_RS19775 0f0986aed4177c8b90327ebc6394ca6a 697 SUPERFAMILY SSF56059 480 696 2.05E-33 T 13-09-2016 THL1_RS19775 0f0986aed4177c8b90327ebc6394ca6a 697 SMART SM00881 9 99 2.3E-18 T 13-09-2016 IPR003781 CoA-binding GO:0048037 THL1_RS19775 0f0986aed4177c8b90327ebc6394ca6a 697 SUPERFAMILY SSF52210 129 286 1.31E-31 T 13-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 THL1_RS19775 0f0986aed4177c8b90327ebc6394ca6a 697 Pfam PF13549 ATP-grasp domain 477 693 4.6E-55 T 13-09-2016 THL1_RS20925 0e71ab0a527ea12ffd631b5ffd6f1d6e 400 SUPERFAMILY SSF53901 264 383 8.0E-24 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20925 0e71ab0a527ea12ffd631b5ffd6f1d6e 400 Gene3D G3DSA:3.40.47.10 146 188 5.4E-18 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20925 0e71ab0a527ea12ffd631b5ffd6f1d6e 400 Gene3D G3DSA:3.40.47.10 253 371 5.4E-18 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20925 0e71ab0a527ea12ffd631b5ffd6f1d6e 400 Pfam PF00108 Thiolase, N-terminal domain 21 227 2.8E-17 T 13-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THL1_RS20925 0e71ab0a527ea12ffd631b5ffd6f1d6e 400 Pfam PF02803 Thiolase, C-terminal domain 270 367 7.6E-7 T 13-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THL1_RS20925 0e71ab0a527ea12ffd631b5ffd6f1d6e 400 SUPERFAMILY SSF53901 9 235 2.31E-36 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20925 0e71ab0a527ea12ffd631b5ffd6f1d6e 400 PANTHER PTHR18919:SF8 4 394 4.4E-86 T 13-09-2016 THL1_RS20925 0e71ab0a527ea12ffd631b5ffd6f1d6e 400 Gene3D G3DSA:3.40.47.10 18 116 9.9E-25 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20925 0e71ab0a527ea12ffd631b5ffd6f1d6e 400 Gene3D G3DSA:3.40.47.10 198 228 9.9E-25 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20925 0e71ab0a527ea12ffd631b5ffd6f1d6e 400 PANTHER PTHR18919 4 394 4.4E-86 T 13-09-2016 THL1_RS20925 0e71ab0a527ea12ffd631b5ffd6f1d6e 400 PIRSF PIRSF000429 4 394 9.9E-70 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS05540 c6b8d6a52b884484e564e9ac57b0cebd 197 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 2 40 1.9E-12 T 13-09-2016 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 THL1_RS05540 c6b8d6a52b884484e564e9ac57b0cebd 197 PANTHER PTHR10134:SF8 1 195 1.5E-104 T 13-09-2016 THL1_RS05540 c6b8d6a52b884484e564e9ac57b0cebd 197 PANTHER PTHR10134 1 195 1.5E-104 T 13-09-2016 IPR014349 Rieske iron-sulphur protein GO:0016679|GO:0055114 THL1_RS05540 c6b8d6a52b884484e564e9ac57b0cebd 197 PRINTS PR00162 Rieske 2Fe-2S subunit signature 119 130 5.0E-9 T 13-09-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 THL1_RS05540 c6b8d6a52b884484e564e9ac57b0cebd 197 PRINTS PR00162 Rieske 2Fe-2S subunit signature 163 175 5.0E-9 T 13-09-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 THL1_RS05540 c6b8d6a52b884484e564e9ac57b0cebd 197 PRINTS PR00162 Rieske 2Fe-2S subunit signature 150 162 5.0E-9 T 13-09-2016 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 THL1_RS05540 c6b8d6a52b884484e564e9ac57b0cebd 197 Gene3D G3DSA:2.102.10.10 7 195 2.4E-44 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS05540 c6b8d6a52b884484e564e9ac57b0cebd 197 SUPERFAMILY SSF50022 30 193 3.3E-42 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS05540 c6b8d6a52b884484e564e9ac57b0cebd 197 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 9 191 2.9E-68 T 13-09-2016 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 THL1_RS05540 c6b8d6a52b884484e564e9ac57b0cebd 197 Pfam PF00355 Rieske [2Fe-2S] domain 110 178 1.2E-10 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS07150 87306b1b2dc863676db915942db5b3d1 275 Gene3D G3DSA:3.40.50.1820 4 271 3.8E-66 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS07150 87306b1b2dc863676db915942db5b3d1 275 PANTHER PTHR10992 8 272 2.6E-55 T 13-09-2016 THL1_RS07150 87306b1b2dc863676db915942db5b3d1 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 5.9E-20 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS07150 87306b1b2dc863676db915942db5b3d1 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 56 71 5.9E-20 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS07150 87306b1b2dc863676db915942db5b3d1 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 5.9E-20 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS07150 87306b1b2dc863676db915942db5b3d1 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 5.9E-20 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS07150 87306b1b2dc863676db915942db5b3d1 275 PRINTS PR00412 Epoxide hydrolase signature 114 127 4.3E-9 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS07150 87306b1b2dc863676db915942db5b3d1 275 PRINTS PR00412 Epoxide hydrolase signature 56 71 4.3E-9 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS07150 87306b1b2dc863676db915942db5b3d1 275 PRINTS PR00412 Epoxide hydrolase signature 247 269 4.3E-9 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS07150 87306b1b2dc863676db915942db5b3d1 275 Pfam PF12697 Alpha/beta hydrolase family 29 263 4.4E-21 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS07150 87306b1b2dc863676db915942db5b3d1 275 SUPERFAMILY SSF53474 5 271 3.99E-66 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS24300 54bd9d2fb8244ce7fba6ed79f98ae578 166 Gene3D G3DSA:3.30.70.560 3 153 6.2E-56 T 13-09-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 THL1_RS24300 54bd9d2fb8244ce7fba6ed79f98ae578 166 SUPERFAMILY SSF55083 1 157 4.45E-53 T 13-09-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 THL1_RS24300 54bd9d2fb8244ce7fba6ed79f98ae578 166 PANTHER PTHR20941:SF10 1 159 5.3E-71 T 13-09-2016 THL1_RS24300 54bd9d2fb8244ce7fba6ed79f98ae578 166 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 133 1.5E-45 T 13-09-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 THL1_RS24300 54bd9d2fb8244ce7fba6ed79f98ae578 166 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 133 2.7E-36 T 13-09-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 THL1_RS24300 54bd9d2fb8244ce7fba6ed79f98ae578 166 PANTHER PTHR20941 1 159 5.3E-71 T 13-09-2016 THL1_RS24300 54bd9d2fb8244ce7fba6ed79f98ae578 166 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 13-09-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 THL1_RS15670 6a1109f4737b4db092d12e2c7385f76c 496 Gene3D G3DSA:3.40.605.10 17 281 3.3E-101 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS15670 6a1109f4737b4db092d12e2c7385f76c 496 Gene3D G3DSA:3.40.309.10 282 467 7.2E-70 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS15670 6a1109f4737b4db092d12e2c7385f76c 496 Pfam PF00171 Aldehyde dehydrogenase family 26 492 1.1E-173 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS15670 6a1109f4737b4db092d12e2c7385f76c 496 PANTHER PTHR11699 1 494 4.8E-232 T 13-09-2016 THL1_RS15670 6a1109f4737b4db092d12e2c7385f76c 496 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 296 307 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS15670 6a1109f4737b4db092d12e2c7385f76c 496 PANTHER PTHR11699:SF46 1 494 4.8E-232 T 13-09-2016 THL1_RS15670 6a1109f4737b4db092d12e2c7385f76c 496 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 268 275 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS15670 6a1109f4737b4db092d12e2c7385f76c 496 SUPERFAMILY SSF53720 10 494 7.85E-174 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS13770 d5a96e4157c8d07dd1d31d71972a6ab9 415 Gene3D G3DSA:1.20.1250.20 223 401 4.7E-18 T 13-09-2016 THL1_RS13770 d5a96e4157c8d07dd1d31d71972a6ab9 415 Gene3D G3DSA:1.20.1250.20 15 204 5.2E-15 T 13-09-2016 THL1_RS13770 d5a96e4157c8d07dd1d31d71972a6ab9 415 SUPERFAMILY SSF103473 15 402 1.44E-45 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS13770 d5a96e4157c8d07dd1d31d71972a6ab9 415 Pfam PF05977 Transmembrane secretion effector 10 395 3.6E-55 T 13-09-2016 IPR010290 Transmembrane secretion effector THL1_RS13770 d5a96e4157c8d07dd1d31d71972a6ab9 415 PANTHER PTHR23513 1 410 7.7E-75 T 13-09-2016 THL1_RS11715 e2a0ddc8d009090c0c568a98a4cec3a5 493 SMART SM00304 161 214 1.6E-6 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS11715 e2a0ddc8d009090c0c568a98a4cec3a5 493 SMART SM00304 215 267 78.0 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS11715 e2a0ddc8d009090c0c568a98a4cec3a5 493 SUPERFAMILY SSF58104 182 491 9.94E-78 T 13-09-2016 THL1_RS11715 e2a0ddc8d009090c0c568a98a4cec3a5 493 Pfam PF00672 HAMP domain 144 207 3.3E-10 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS11715 e2a0ddc8d009090c0c568a98a4cec3a5 493 Gene3D G3DSA:1.10.287.950 244 459 2.1E-57 T 13-09-2016 THL1_RS11715 e2a0ddc8d009090c0c568a98a4cec3a5 493 SMART SM00283 229 490 1.8E-69 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS11715 e2a0ddc8d009090c0c568a98a4cec3a5 493 PANTHER PTHR32089:SF34 110 493 7.7E-132 T 13-09-2016 THL1_RS11715 e2a0ddc8d009090c0c568a98a4cec3a5 493 PANTHER PTHR32089 110 493 7.7E-132 T 13-09-2016 THL1_RS11715 e2a0ddc8d009090c0c568a98a4cec3a5 493 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 243 272 4.8E-6 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS11715 e2a0ddc8d009090c0c568a98a4cec3a5 493 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 356 385 4.8E-6 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS11715 e2a0ddc8d009090c0c568a98a4cec3a5 493 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 300 488 3.2E-46 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS08645 c4a61223db13be58b2ca55161f1b347d 308 Gene3D G3DSA:3.40.190.10 87 179 1.3E-9 T 13-09-2016 THL1_RS08645 c4a61223db13be58b2ca55161f1b347d 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.2E-17 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08645 c4a61223db13be58b2ca55161f1b347d 308 PANTHER PTHR30126 5 307 6.1E-151 T 13-09-2016 THL1_RS08645 c4a61223db13be58b2ca55161f1b347d 308 PANTHER PTHR30126:SF19 5 307 6.1E-151 T 13-09-2016 THL1_RS08645 c4a61223db13be58b2ca55161f1b347d 308 SUPERFAMILY SSF53850 93 292 6.15E-29 T 13-09-2016 THL1_RS08645 c4a61223db13be58b2ca55161f1b347d 308 Gene3D G3DSA:3.40.190.10 180 256 4.2E-9 T 13-09-2016 THL1_RS08645 c4a61223db13be58b2ca55161f1b347d 308 Gene3D G3DSA:1.10.10.10 7 86 7.3E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08645 c4a61223db13be58b2ca55161f1b347d 308 Pfam PF03466 LysR substrate binding domain 92 290 7.4E-27 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS08645 c4a61223db13be58b2ca55161f1b347d 308 SUPERFAMILY SSF46785 5 104 1.14E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00615 5ea35ca68aaede277e9d9d3df5b8b6db 483 Gene3D G3DSA:3.40.605.10 10 267 6.7E-105 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS00615 5ea35ca68aaede277e9d9d3df5b8b6db 483 Gene3D G3DSA:3.40.309.10 268 453 7.5E-70 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS00615 5ea35ca68aaede277e9d9d3df5b8b6db 483 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS00615 5ea35ca68aaede277e9d9d3df5b8b6db 483 PANTHER PTHR11699:SF49 1 480 1.1E-303 T 13-09-2016 THL1_RS00615 5ea35ca68aaede277e9d9d3df5b8b6db 483 SUPERFAMILY SSF53720 6 481 7.98E-177 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS00615 5ea35ca68aaede277e9d9d3df5b8b6db 483 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 30 476 1.8E-235 T 13-09-2016 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 UniPathway: UPA00733 THL1_RS00615 5ea35ca68aaede277e9d9d3df5b8b6db 483 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS00615 5ea35ca68aaede277e9d9d3df5b8b6db 483 PANTHER PTHR11699 1 480 1.1E-303 T 13-09-2016 THL1_RS00615 5ea35ca68aaede277e9d9d3df5b8b6db 483 Pfam PF00171 Aldehyde dehydrogenase family 19 477 1.6E-173 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS26340 c8090a22b77871a1a0793567e3d4cc67 484 Gene3D G3DSA:3.30.2010.10 55 139 1.8E-20 T 13-09-2016 THL1_RS26340 c8090a22b77871a1a0793567e3d4cc67 484 Pfam PF01435 Peptidase family M48 62 250 7.9E-39 T 13-09-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 THL1_RS26340 c8090a22b77871a1a0793567e3d4cc67 484 PANTHER PTHR22726 21 349 3.7E-111 T 13-09-2016 THL1_RS26340 c8090a22b77871a1a0793567e3d4cc67 484 PANTHER PTHR22726:SF9 21 349 3.7E-111 T 13-09-2016 THL1_RS28000 496879686e5d219351ac910e79adc4c3 446 Pfam PF00571 CBS domain 237 288 8.4E-8 T 13-09-2016 IPR000644 CBS domain THL1_RS28000 496879686e5d219351ac910e79adc4c3 446 Pfam PF00571 CBS domain 302 353 7.9E-6 T 13-09-2016 IPR000644 CBS domain THL1_RS28000 496879686e5d219351ac910e79adc4c3 446 SMART SM00116 239 288 4.6E-6 T 13-09-2016 IPR000644 CBS domain THL1_RS28000 496879686e5d219351ac910e79adc4c3 446 SMART SM00116 305 353 0.03 T 13-09-2016 IPR000644 CBS domain THL1_RS28000 496879686e5d219351ac910e79adc4c3 446 SUPERFAMILY SSF56176 369 445 2.1E-15 T 13-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THL1_RS28000 496879686e5d219351ac910e79adc4c3 446 Pfam PF03471 Transporter associated domain 372 444 6.9E-17 T 13-09-2016 IPR005170 Transporter-associated domain THL1_RS28000 496879686e5d219351ac910e79adc4c3 446 PANTHER PTHR22777:SF18 19 446 8.2E-179 T 13-09-2016 THL1_RS28000 496879686e5d219351ac910e79adc4c3 446 Gene3D G3DSA:3.30.465.10 361 445 1.5E-18 T 13-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THL1_RS28000 496879686e5d219351ac910e79adc4c3 446 Gene3D G3DSA:3.10.580.10 220 360 1.1E-20 T 13-09-2016 THL1_RS28000 496879686e5d219351ac910e79adc4c3 446 PANTHER PTHR22777 19 446 8.2E-179 T 13-09-2016 THL1_RS28000 496879686e5d219351ac910e79adc4c3 446 Pfam PF01595 Domain of unknown function DUF21 21 209 1.1E-49 T 13-09-2016 IPR002550 Domain of unknown function DUF21 THL1_RS28000 496879686e5d219351ac910e79adc4c3 446 SUPERFAMILY SSF54631 227 367 6.95E-27 T 13-09-2016 THL1_RS28000 496879686e5d219351ac910e79adc4c3 446 SMART SM01091 368 446 8.1E-17 T 13-09-2016 IPR005170 Transporter-associated domain THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 SUPERFAMILY SSF101353 254 459 3.53E-62 T 13-09-2016 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7|Reactome: REACT_71 THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 PANTHER PTHR11777:SF9 1 874 0.0 T 13-09-2016 THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 Pfam PF02272 DHHA1 domain 800 866 7.6E-14 T 13-09-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 Pfam PF01411 tRNA synthetases class II (A) 5 552 2.3E-226 T 13-09-2016 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 Gene3D G3DSA:3.30.930.10 1 249 1.1E-124 T 13-09-2016 THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 234 247 3.1E-31 T 13-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 207 218 3.1E-31 T 13-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 304 317 3.1E-31 T 13-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 3.1E-31 T 13-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 280 296 3.1E-31 T 13-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 SMART SM00863 651 695 7.5E-23 T 13-09-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 SUPERFAMILY SSF55186 550 707 9.29E-51 T 13-09-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 651 695 5.6E-19 T 13-09-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 853 0.0 T 13-09-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 PANTHER PTHR11777 1 874 0.0 T 13-09-2016 THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 SUPERFAMILY SSF50447 453 550 3.88E-17 T 13-09-2016 IPR009000 Translation protein, beta-barrel domain THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 874 205.79 T 13-09-2016 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 THL1_RS21160 a14df1bf6319059dd668d6f2b854c349 874 SUPERFAMILY SSF55681 2 253 7.95E-107 T 13-09-2016 THL1_RS07510 708288de534fafc003410758b4fdad64 309 PANTHER PTHR22924:SF20 4 267 3.0E-66 T 13-09-2016 THL1_RS07510 708288de534fafc003410758b4fdad64 309 PANTHER PTHR22924 4 267 3.0E-66 T 13-09-2016 THL1_RS07510 708288de534fafc003410758b4fdad64 309 SUPERFAMILY SSF54292 207 302 2.1E-23 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS07510 708288de534fafc003410758b4fdad64 309 SUPERFAMILY SSF63380 3 98 6.35E-24 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS07510 708288de534fafc003410758b4fdad64 309 Gene3D G3DSA:3.10.20.30 214 300 5.2E-24 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS07510 708288de534fafc003410758b4fdad64 309 Gene3D G3DSA:2.40.30.10 4 98 4.0E-28 T 13-09-2016 THL1_RS07510 708288de534fafc003410758b4fdad64 309 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 231 289 1.0E-10 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS07510 708288de534fafc003410758b4fdad64 309 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 260 268 - T 13-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THL1_RS07510 708288de534fafc003410758b4fdad64 309 Gene3D G3DSA:3.40.50.80 101 213 6.8E-20 T 13-09-2016 THL1_RS07510 708288de534fafc003410758b4fdad64 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 88 102 9.8E-37 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS07510 708288de534fafc003410758b4fdad64 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 28 38 9.8E-37 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS07510 708288de534fafc003410758b4fdad64 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 185 193 9.8E-37 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS07510 708288de534fafc003410758b4fdad64 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 110 129 9.8E-37 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS07510 708288de534fafc003410758b4fdad64 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 50 64 9.8E-37 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS07510 708288de534fafc003410758b4fdad64 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 38 50 9.8E-37 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS07510 708288de534fafc003410758b4fdad64 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 135 144 9.8E-37 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS07510 708288de534fafc003410758b4fdad64 309 PRINTS PR00409 Phthalate dioxygenase reductase family signature 74 88 9.8E-37 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS07510 708288de534fafc003410758b4fdad64 309 SUPERFAMILY SSF52343 96 226 3.93E-24 T 13-09-2016 THL1_RS10785 94e873f2462345fc6cbc942aec828de3 334 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 6 331 37.963 T 13-09-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130|UniPathway: UPA00359 THL1_RS10785 94e873f2462345fc6cbc942aec828de3 334 PANTHER PTHR30160 4 318 6.2E-85 T 13-09-2016 THL1_RS10785 94e873f2462345fc6cbc942aec828de3 334 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 20 326 1.4E-104 T 13-09-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130|UniPathway: UPA00359 THL1_RS10785 94e873f2462345fc6cbc942aec828de3 334 PANTHER PTHR30160:SF13 4 318 6.2E-85 T 13-09-2016 THL1_RS10785 94e873f2462345fc6cbc942aec828de3 334 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 25 314 9.0E-80 T 13-09-2016 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00030+2.7.1.13|KEGG: 00540+2.7.1.130|UniPathway: UPA00359 THL1_RS10785 94e873f2462345fc6cbc942aec828de3 334 Gene3D G3DSA:3.40.50.300 50 108 3.3E-6 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10785 94e873f2462345fc6cbc942aec828de3 334 Gene3D G3DSA:3.40.50.300 142 149 3.3E-6 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10785 94e873f2462345fc6cbc942aec828de3 334 SUPERFAMILY SSF52540 52 193 1.15E-13 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08570 f2d5805be9e06e17e306ff2dba86addd 283 TIGRFAM TIGR04553 ABC_peri_selen: putative selenate ABC transporter periplasmic binding protein 26 283 8.7E-114 T 13-09-2016 IPR030836 Putative selenate ABC transporter periplasmic binding protein THL1_RS08570 f2d5805be9e06e17e306ff2dba86addd 283 SUPERFAMILY SSF53850 49 231 3.4E-39 T 13-09-2016 THL1_RS08570 f2d5805be9e06e17e306ff2dba86addd 283 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 5 242 6.2E-73 T 13-09-2016 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 THL1_RS08570 f2d5805be9e06e17e306ff2dba86addd 283 PANTHER PTHR30024 1 238 5.2E-62 T 13-09-2016 THL1_RS08570 f2d5805be9e06e17e306ff2dba86addd 283 Gene3D G3DSA:3.40.190.10 50 128 2.9E-5 T 13-09-2016 THL1_RS08570 f2d5805be9e06e17e306ff2dba86addd 283 PANTHER PTHR30024:SF17 1 238 5.2E-62 T 13-09-2016 THL1_RS08570 f2d5805be9e06e17e306ff2dba86addd 283 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 30 269 1.8E-67 T 13-09-2016 THL1_RS08570 f2d5805be9e06e17e306ff2dba86addd 283 Gene3D G3DSA:3.40.190.10 129 228 1.3E-12 T 13-09-2016 THL1_RS17885 7e85e5e760d55ebaa448a2408c83b575 629 PANTHER PTHR11236:SF2 407 480 4.2E-140 T 13-09-2016 THL1_RS17885 7e85e5e760d55ebaa448a2408c83b575 629 PANTHER PTHR11236 407 480 4.2E-140 T 13-09-2016 THL1_RS17885 7e85e5e760d55ebaa448a2408c83b575 629 Pfam PF00117 Glutamine amidotransferase class-I 445 620 1.8E-21 T 13-09-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 THL1_RS17885 7e85e5e760d55ebaa448a2408c83b575 629 Gene3D G3DSA:3.40.50.880 442 624 5.1E-28 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS17885 7e85e5e760d55ebaa448a2408c83b575 629 Pfam PF00425 chorismate binding enzyme 119 372 4.1E-43 T 13-09-2016 IPR015890 Chorismate-utilising enzyme, C-terminal THL1_RS17885 7e85e5e760d55ebaa448a2408c83b575 629 SUPERFAMILY SSF52317 440 621 1.91E-22 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS17885 7e85e5e760d55ebaa448a2408c83b575 629 PANTHER PTHR11236 93 391 4.2E-140 T 13-09-2016 THL1_RS17885 7e85e5e760d55ebaa448a2408c83b575 629 Gene3D G3DSA:3.60.120.10 112 384 8.1E-53 T 13-09-2016 IPR005801 ADC synthase GO:0009058 THL1_RS17885 7e85e5e760d55ebaa448a2408c83b575 629 PRINTS PR00096 Glutamine amidotransferase superfamily signature 603 616 2.1E-7 T 13-09-2016 THL1_RS17885 7e85e5e760d55ebaa448a2408c83b575 629 PRINTS PR00096 Glutamine amidotransferase superfamily signature 484 493 2.1E-7 T 13-09-2016 THL1_RS17885 7e85e5e760d55ebaa448a2408c83b575 629 PRINTS PR00096 Glutamine amidotransferase superfamily signature 517 528 2.1E-7 T 13-09-2016 THL1_RS17885 7e85e5e760d55ebaa448a2408c83b575 629 SUPERFAMILY SSF56322 107 381 9.03E-60 T 13-09-2016 IPR005801 ADC synthase GO:0009058 THL1_RS17885 7e85e5e760d55ebaa448a2408c83b575 629 PANTHER PTHR11236:SF2 93 391 4.2E-140 T 13-09-2016 THL1_RS17885 7e85e5e760d55ebaa448a2408c83b575 629 PRINTS PR00097 Anthranilate synthase component II signature 443 457 1.9E-8 T 13-09-2016 THL1_RS17885 7e85e5e760d55ebaa448a2408c83b575 629 PRINTS PR00097 Anthranilate synthase component II signature 484 493 1.9E-8 T 13-09-2016 THL1_RS17885 7e85e5e760d55ebaa448a2408c83b575 629 PRINTS PR00097 Anthranilate synthase component II signature 603 616 1.9E-8 T 13-09-2016 THL1_RS18455 4653c32e60278de7c2addb5a05255fd9 272 PANTHER PTHR35936 1 267 5.5E-17 T 13-09-2016 THL1_RS18455 4653c32e60278de7c2addb5a05255fd9 272 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 247 3.0E-22 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS18455 4653c32e60278de7c2addb5a05255fd9 272 SMART SM00062 28 259 2.1E-4 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS18455 4653c32e60278de7c2addb5a05255fd9 272 PANTHER PTHR35936:SF3 1 267 5.5E-17 T 13-09-2016 THL1_RS18455 4653c32e60278de7c2addb5a05255fd9 272 Gene3D G3DSA:3.40.190.10 10 144 1.3E-16 T 13-09-2016 THL1_RS18455 4653c32e60278de7c2addb5a05255fd9 272 SUPERFAMILY SSF53850 31 257 1.21E-37 T 13-09-2016 THL1_RS06605 eadabc32d8f7ee40e87acb927b1b6478 189 SUPERFAMILY SSF55729 5 172 1.65E-30 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS06605 eadabc32d8f7ee40e87acb927b1b6478 189 PANTHER PTHR13256:SF20 1 184 7.2E-64 T 13-09-2016 THL1_RS06605 eadabc32d8f7ee40e87acb927b1b6478 189 PANTHER PTHR13256 1 184 7.2E-64 T 13-09-2016 THL1_RS06605 eadabc32d8f7ee40e87acb927b1b6478 189 Gene3D G3DSA:3.40.630.30 3 186 1.6E-54 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS06605 eadabc32d8f7ee40e87acb927b1b6478 189 Pfam PF13302 Acetyltransferase (GNAT) domain 14 146 1.3E-11 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS01500 37d093fcd1085b63f6062461dea19263 146 Pfam PF03652 Holliday junction resolvase 10 140 6.2E-41 T 13-09-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 THL1_RS01500 37d093fcd1085b63f6062461dea19263 146 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 8 143 24.858 T 13-09-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 THL1_RS01500 37d093fcd1085b63f6062461dea19263 146 SMART SM00732 8 108 1.5E-39 T 13-09-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 THL1_RS01500 37d093fcd1085b63f6062461dea19263 146 Gene3D G3DSA:3.30.420.140 10 143 2.4E-45 T 13-09-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 THL1_RS01500 37d093fcd1085b63f6062461dea19263 146 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 11 139 4.2E-42 T 13-09-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 THL1_RS01500 37d093fcd1085b63f6062461dea19263 146 SUPERFAMILY SSF53098 9 140 1.05E-40 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS01500 37d093fcd1085b63f6062461dea19263 146 PANTHER PTHR33317 10 139 1.9E-40 T 13-09-2016 THL1_RS06425 1d01fc401f740fcee1df8bdac5b4c719 476 SUPERFAMILY SSF53098 5 461 5.46E-120 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS06425 1d01fc401f740fcee1df8bdac5b4c719 476 Pfam PF08411 Exonuclease C-terminal 205 468 4.2E-96 T 13-09-2016 IPR013620 Exonuclease C-terminal GO:0006281|GO:0008852 THL1_RS06425 1d01fc401f740fcee1df8bdac5b4c719 476 PANTHER PTHR11046:SF2 3 467 4.2E-236 T 13-09-2016 IPR023607 Exodeoxyribonuclease I GO:0004529 THL1_RS06425 1d01fc401f740fcee1df8bdac5b4c719 476 Gene3D G3DSA:3.30.420.10 3 194 2.2E-75 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS06425 1d01fc401f740fcee1df8bdac5b4c719 476 PANTHER PTHR11046 3 467 4.2E-236 T 13-09-2016 THL1_RS06425 1d01fc401f740fcee1df8bdac5b4c719 476 PIRSF PIRSF000977 1 475 1.3E-200 T 13-09-2016 IPR023607 Exodeoxyribonuclease I GO:0004529 THL1_RS06425 1d01fc401f740fcee1df8bdac5b4c719 476 Pfam PF00929 Exonuclease 7 186 3.4E-22 T 13-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 Gene3D G3DSA:3.40.50.300 417 578 7.4E-38 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 Pfam PF12344 Ultra-violet resistance protein B 550 591 2.2E-20 T 13-09-2016 IPR024759 UvrB, YAD/RRR-motif-containing domain THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 SMART SM00487 8 424 3.1E-27 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 Gene3D G3DSA:3.40.50.300 387 408 4.2E-52 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 Gene3D G3DSA:3.40.50.300 277 337 4.2E-52 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 Gene3D G3DSA:3.40.50.300 5 88 4.2E-52 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 3 665 0.0 T 13-09-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 SMART SM00490 458 544 8.9E-17 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 SUPERFAMILY SSF52540 36 81 3.6E-35 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 SUPERFAMILY SSF52540 457 582 3.6E-35 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 Gene3D G3DSA:4.10.860.10 627 669 2.9E-15 T 13-09-2016 IPR001943 UVR domain GO:0005515 THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 Pfam PF04851 Type III restriction enzyme, res subunit 11 91 9.1E-9 T 13-09-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 Gene3D G3DSA:3.30.2060.10 159 232 5.8E-9 T 13-09-2016 THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 SUPERFAMILY SSF46600 625 669 2.75E-10 T 13-09-2016 IPR001943 UVR domain GO:0005515 THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 SUPERFAMILY SSF52540 3 413 4.21E-138 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 PANTHER PTHR24029 1 671 0.0 T 13-09-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 Pfam PF02151 UvrB/uvrC motif 633 666 6.1E-8 T 13-09-2016 IPR001943 UVR domain GO:0005515 THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 Hamap MF_00204 UvrABC system protein B [uvrB]. 2 667 43.413 T 13-09-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 THL1_RS09910 78a71099e59b320550bd5c99ee6b75fb 671 Pfam PF00271 Helicase conserved C-terminal domain 432 543 1.2E-17 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS19945 94c5c64d552ce210c55671b205899770 229 Gene3D G3DSA:3.40.50.720 1 229 1.8E-72 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS19945 94c5c64d552ce210c55671b205899770 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 157 7.0E-29 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19945 94c5c64d552ce210c55671b205899770 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 66 77 7.0E-29 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19945 94c5c64d552ce210c55671b205899770 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 111 127 7.0E-29 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19945 94c5c64d552ce210c55671b205899770 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 176 7.0E-29 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19945 94c5c64d552ce210c55671b205899770 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 211 7.0E-29 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19945 94c5c64d552ce210c55671b205899770 229 PANTHER PTHR24322 1 121 1.3E-46 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19945 94c5c64d552ce210c55671b205899770 229 PANTHER PTHR24322 138 170 1.3E-46 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19945 94c5c64d552ce210c55671b205899770 229 SUPERFAMILY SSF51735 1 229 1.45E-71 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS19945 94c5c64d552ce210c55671b205899770 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 66 77 2.4E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19945 94c5c64d552ce210c55671b205899770 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 157 2.4E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19945 94c5c64d552ce210c55671b205899770 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 117 125 2.4E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19945 94c5c64d552ce210c55671b205899770 229 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 1 228 3.8E-59 T 13-09-2016 THL1_RS05920 93647bbc5c6305ba57a619212a2a3860 258 PANTHER PTHR23416 1 218 3.4E-103 T 13-09-2016 THL1_RS05920 93647bbc5c6305ba57a619212a2a3860 258 PANTHER PTHR23416:SF55 1 218 3.4E-103 T 13-09-2016 THL1_RS05920 93647bbc5c6305ba57a619212a2a3860 258 SUPERFAMILY SSF51161 2 174 3.6E-56 T 13-09-2016 IPR011004 Trimeric LpxA-like THL1_RS05920 93647bbc5c6305ba57a619212a2a3860 258 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 5 166 7.7E-79 T 13-09-2016 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|UniPathway: UPA00136 THL1_RS05920 93647bbc5c6305ba57a619212a2a3860 258 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 71 108 0.0024 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS05920 93647bbc5c6305ba57a619212a2a3860 258 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 118 152 7.5E-7 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS05920 93647bbc5c6305ba57a619212a2a3860 258 Gene3D G3DSA:1.10.3130.10 1 58 2.5E-28 T 13-09-2016 THL1_RS05920 93647bbc5c6305ba57a619212a2a3860 258 Gene3D G3DSA:2.160.10.10 59 181 4.0E-37 T 13-09-2016 THL1_RS24940 77ac5a7dc1519f469902bc75797bdf94 448 SUPERFAMILY SSF53383 19 445 6.59E-115 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS24940 77ac5a7dc1519f469902bc75797bdf94 448 Pfam PF00202 Aminotransferase class-III 25 444 2.2E-122 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS24940 77ac5a7dc1519f469902bc75797bdf94 448 Gene3D G3DSA:3.40.640.10 71 348 2.3E-79 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS24940 77ac5a7dc1519f469902bc75797bdf94 448 Gene3D G3DSA:3.90.1150.10 350 446 1.0E-33 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS24940 77ac5a7dc1519f469902bc75797bdf94 448 Gene3D G3DSA:3.90.1150.10 14 69 1.0E-33 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS24940 77ac5a7dc1519f469902bc75797bdf94 448 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 256 293 - T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS24940 77ac5a7dc1519f469902bc75797bdf94 448 PANTHER PTHR11986 20 445 8.9E-263 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS24940 77ac5a7dc1519f469902bc75797bdf94 448 PANTHER PTHR11986:SF72 20 445 8.9E-263 T 13-09-2016 THL1_RS09240 d77c2da0db024b2795495f0e2abded72 339 SMART SM00342 256 338 8.1E-24 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS09240 d77c2da0db024b2795495f0e2abded72 339 Pfam PF12833 Helix-turn-helix domain 262 338 3.6E-17 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS09240 d77c2da0db024b2795495f0e2abded72 339 Gene3D G3DSA:1.10.10.60 239 277 5.9E-4 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS09240 d77c2da0db024b2795495f0e2abded72 339 PANTHER PTHR11019 129 178 2.0E-40 T 13-09-2016 THL1_RS09240 d77c2da0db024b2795495f0e2abded72 339 PANTHER PTHR11019 223 338 2.0E-40 T 13-09-2016 THL1_RS09240 d77c2da0db024b2795495f0e2abded72 339 PANTHER PTHR11019:SF52 129 178 2.0E-40 T 13-09-2016 THL1_RS09240 d77c2da0db024b2795495f0e2abded72 339 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 29 213 2.3E-44 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS09240 d77c2da0db024b2795495f0e2abded72 339 SUPERFAMILY SSF46689 291 338 9.68E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS09240 d77c2da0db024b2795495f0e2abded72 339 Gene3D G3DSA:1.10.10.60 290 338 5.4E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS09240 d77c2da0db024b2795495f0e2abded72 339 PANTHER PTHR11019:SF52 223 338 2.0E-40 T 13-09-2016 THL1_RS04505 ec9884f44bde2a7ee467e4be977761b9 158 Gene3D G3DSA:3.30.70.920 54 128 6.8E-16 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS04505 ec9884f44bde2a7ee467e4be977761b9 158 SUPERFAMILY SSF54909 63 137 4.96E-14 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS04505 ec9884f44bde2a7ee467e4be977761b9 158 Pfam PF13404 AsnC-type helix-turn-helix domain 2 42 1.8E-15 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS04505 ec9884f44bde2a7ee467e4be977761b9 158 Pfam PF01037 Lrp/AsnC ligand binding domain 68 134 5.3E-13 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS04505 ec9884f44bde2a7ee467e4be977761b9 158 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 13-09-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site THL1_RS04505 ec9884f44bde2a7ee467e4be977761b9 158 SMART SM00344 1 107 6.3E-28 T 13-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 THL1_RS04505 ec9884f44bde2a7ee467e4be977761b9 158 Gene3D G3DSA:1.10.10.10 2 52 1.5E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS04505 ec9884f44bde2a7ee467e4be977761b9 158 PANTHER PTHR30154 2 158 8.3E-46 T 13-09-2016 THL1_RS04505 ec9884f44bde2a7ee467e4be977761b9 158 SUPERFAMILY SSF46785 1 60 9.36E-16 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS04505 ec9884f44bde2a7ee467e4be977761b9 158 PANTHER PTHR30154:SF2 2 158 8.3E-46 T 13-09-2016 THL1_RS04505 ec9884f44bde2a7ee467e4be977761b9 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 6.8E-12 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS04505 ec9884f44bde2a7ee467e4be977761b9 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 6.8E-12 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS04505 ec9884f44bde2a7ee467e4be977761b9 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 6.8E-12 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 Gene3D G3DSA:3.40.50.720 2 255 1.1E-78 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.2E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.2E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.2E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 SUPERFAMILY SSF51735 1 255 1.27E-73 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.0E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.0E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.0E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.0E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.0E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.0E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 254 3.2E-55 T 13-09-2016 THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 PANTHER PTHR24322 10 136 2.5E-53 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 PANTHER PTHR24322:SF330 10 136 2.5E-53 T 13-09-2016 THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 PANTHER PTHR24322:SF330 152 184 2.5E-53 T 13-09-2016 THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 PANTHER PTHR24322 152 184 2.5E-53 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 6 256 4.8E-107 T 13-09-2016 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 THL1_RS16990 10b1bf7fd9608aff84c19d03df5c94e0 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS11940 253f5433229aed28e7728f92608b1baa 507 PANTHER PTHR33908:SF3 5 382 1.5E-74 T 13-09-2016 THL1_RS11940 253f5433229aed28e7728f92608b1baa 507 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 64 227 4.7E-19 T 13-09-2016 THL1_RS11940 253f5433229aed28e7728f92608b1baa 507 PANTHER PTHR33908 5 382 1.5E-74 T 13-09-2016 THL1_RS08455 6d0b89c6c979dae05454f1bf2813f477 96 Gene3D G3DSA:3.10.580.10 32 75 6.8E-5 T 13-09-2016 THL1_RS08455 6d0b89c6c979dae05454f1bf2813f477 96 SUPERFAMILY SSF54631 4 76 3.66E-6 T 13-09-2016 THL1_RS03740 26e5a641ae443047cd6ac65c62c4a2b3 333 PANTHER PTHR32039 7 304 3.5E-108 T 13-09-2016 THL1_RS03740 26e5a641ae443047cd6ac65c62c4a2b3 333 SMART SM00382 30 192 1.7E-5 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS03740 26e5a641ae443047cd6ac65c62c4a2b3 333 Pfam PF07728 AAA domain (dynein-related subfamily) 33 163 4.0E-12 T 13-09-2016 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 THL1_RS03740 26e5a641ae443047cd6ac65c62c4a2b3 333 Gene3D G3DSA:1.10.8.80 216 289 2.6E-24 T 13-09-2016 THL1_RS03740 26e5a641ae443047cd6ac65c62c4a2b3 333 Gene3D G3DSA:3.40.50.300 5 167 3.1E-49 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03740 26e5a641ae443047cd6ac65c62c4a2b3 333 PANTHER PTHR32039:SF10 7 304 3.5E-108 T 13-09-2016 THL1_RS03740 26e5a641ae443047cd6ac65c62c4a2b3 333 SUPERFAMILY SSF52540 5 283 1.19E-54 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03520 e2b866753d78b7f32a78f2a98f203cce 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 1.2E-35 T 13-09-2016 IPR027486 Ribosomal protein S10 domain THL1_RS03520 e2b866753d78b7f32a78f2a98f203cce 103 Gene3D G3DSA:3.30.70.600 3 102 6.2E-44 T 13-09-2016 IPR027486 Ribosomal protein S10 domain THL1_RS03520 e2b866753d78b7f32a78f2a98f203cce 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 26.997 T 13-09-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 THL1_RS03520 e2b866753d78b7f32a78f2a98f203cce 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 13-09-2016 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03520 e2b866753d78b7f32a78f2a98f203cce 103 PANTHER PTHR11700 1 102 5.0E-55 T 13-09-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 THL1_RS03520 e2b866753d78b7f32a78f2a98f203cce 103 SMART SM01403 7 101 7.9E-56 T 13-09-2016 IPR027486 Ribosomal protein S10 domain THL1_RS03520 e2b866753d78b7f32a78f2a98f203cce 103 SUPERFAMILY SSF54999 6 101 9.29E-37 T 13-09-2016 IPR027486 Ribosomal protein S10 domain THL1_RS03520 e2b866753d78b7f32a78f2a98f203cce 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 2.2E-46 T 13-09-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 THL1_RS03520 e2b866753d78b7f32a78f2a98f203cce 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 4.1E-18 T 13-09-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 THL1_RS03520 e2b866753d78b7f32a78f2a98f203cce 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 4.1E-18 T 13-09-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 THL1_RS03520 e2b866753d78b7f32a78f2a98f203cce 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 4.1E-18 T 13-09-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 THL1_RS11935 fb9de9600e4fffefe147f7dbf67e639b 302 Pfam PF06977 SdiA-regulated 46 300 1.5E-88 T 13-09-2016 IPR009722 SdiA-regulated THL1_RS11935 fb9de9600e4fffefe147f7dbf67e639b 302 Gene3D G3DSA:2.120.10.30 69 293 3.6E-10 T 13-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like THL1_RS11935 fb9de9600e4fffefe147f7dbf67e639b 302 SUPERFAMILY SSF50956 23 302 1.44E-31 T 13-09-2016 THL1_RS24965 efcbca3f1ccfad61e93f41807dfc94c3 324 PANTHER PTHR33055:SF3 1 318 1.0E-60 T 13-09-2016 THL1_RS24965 efcbca3f1ccfad61e93f41807dfc94c3 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 197 280 1.9E-21 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS24965 efcbca3f1ccfad61e93f41807dfc94c3 324 Pfam PF01548 Transposase 5 153 2.7E-32 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS24965 efcbca3f1ccfad61e93f41807dfc94c3 324 PANTHER PTHR33055 1 318 1.0E-60 T 13-09-2016 THL1_RS13380 efcbca3f1ccfad61e93f41807dfc94c3 324 PANTHER PTHR33055:SF3 1 318 1.0E-60 T 13-09-2016 THL1_RS13380 efcbca3f1ccfad61e93f41807dfc94c3 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 197 280 1.9E-21 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS13380 efcbca3f1ccfad61e93f41807dfc94c3 324 Pfam PF01548 Transposase 5 153 2.7E-32 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS13380 efcbca3f1ccfad61e93f41807dfc94c3 324 PANTHER PTHR33055 1 318 1.0E-60 T 13-09-2016 THL1_RS24870 efcbca3f1ccfad61e93f41807dfc94c3 324 PANTHER PTHR33055:SF3 1 318 1.0E-60 T 13-09-2016 THL1_RS24870 efcbca3f1ccfad61e93f41807dfc94c3 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 197 280 1.9E-21 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS24870 efcbca3f1ccfad61e93f41807dfc94c3 324 Pfam PF01548 Transposase 5 153 2.7E-32 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS24870 efcbca3f1ccfad61e93f41807dfc94c3 324 PANTHER PTHR33055 1 318 1.0E-60 T 13-09-2016 THL1_RS20650 a94b06d58505b6cc01e6431d907098e8 294 Gene3D G3DSA:3.40.50.720 1 258 1.8E-75 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20650 a94b06d58505b6cc01e6431d907098e8 294 PANTHER PTHR24321 2 257 1.0E-42 T 13-09-2016 THL1_RS20650 a94b06d58505b6cc01e6431d907098e8 294 PANTHER PTHR24321:SF6 2 257 1.0E-42 T 13-09-2016 THL1_RS20650 a94b06d58505b6cc01e6431d907098e8 294 SUPERFAMILY SSF51735 5 257 8.01E-72 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20650 a94b06d58505b6cc01e6431d907098e8 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.6E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20650 a94b06d58505b6cc01e6431d907098e8 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 2.6E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20650 a94b06d58505b6cc01e6431d907098e8 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.6E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20650 a94b06d58505b6cc01e6431d907098e8 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.6E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20650 a94b06d58505b6cc01e6431d907098e8 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.6E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20650 a94b06d58505b6cc01e6431d907098e8 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.6E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20650 a94b06d58505b6cc01e6431d907098e8 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.3E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20650 a94b06d58505b6cc01e6431d907098e8 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.3E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20650 a94b06d58505b6cc01e6431d907098e8 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.3E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20650 a94b06d58505b6cc01e6431d907098e8 294 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 256 6.0E-60 T 13-09-2016 THL1_RS25965 78b9d6be5bd16cf8d0f020dadffc6b23 327 Pfam PF13449 Esterase-like activity of phytase 39 185 9.0E-8 T 13-09-2016 IPR027372 Phytase-like domain THL1_RS25965 78b9d6be5bd16cf8d0f020dadffc6b23 327 SUPERFAMILY SSF101898 227 267 3.66E-7 T 13-09-2016 THL1_RS25965 78b9d6be5bd16cf8d0f020dadffc6b23 327 SUPERFAMILY SSF101898 38 187 3.66E-7 T 13-09-2016 THL1_RS17415 4ec20b8a3699002c1a7a527582f25ed6 393 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 136 227 2.8E-21 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS17415 4ec20b8a3699002c1a7a527582f25ed6 393 PANTHER PTHR10909 1 392 5.5E-264 T 13-09-2016 THL1_RS17415 4ec20b8a3699002c1a7a527582f25ed6 393 SUPERFAMILY SSF56645 7 238 5.89E-75 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS17415 4ec20b8a3699002c1a7a527582f25ed6 393 Gene3D G3DSA:1.20.140.10 227 388 6.2E-44 T 13-09-2016 THL1_RS17415 4ec20b8a3699002c1a7a527582f25ed6 393 SUPERFAMILY SSF47203 243 390 4.67E-42 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS17415 4ec20b8a3699002c1a7a527582f25ed6 393 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 345 364 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS17415 4ec20b8a3699002c1a7a527582f25ed6 393 Gene3D G3DSA:2.40.110.10 135 226 7.8E-32 T 13-09-2016 THL1_RS17415 4ec20b8a3699002c1a7a527582f25ed6 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 20 132 5.5E-34 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS17415 4ec20b8a3699002c1a7a527582f25ed6 393 Gene3D G3DSA:1.10.540.10 5 134 1.3E-39 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS17415 4ec20b8a3699002c1a7a527582f25ed6 393 PANTHER PTHR10909:SF307 1 392 5.5E-264 T 13-09-2016 THL1_RS17415 4ec20b8a3699002c1a7a527582f25ed6 393 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 385 5.7E-28 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS24520 3ccd37d5efc8bdd49f4ff7a025379cd0 144 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 11 135 1.9E-32 T 13-09-2016 IPR005031 Coenzyme Q-binding protein COQ10, START domain THL1_RS24520 3ccd37d5efc8bdd49f4ff7a025379cd0 144 PANTHER PTHR12901:SF7 3 144 1.7E-68 T 13-09-2016 THL1_RS24520 3ccd37d5efc8bdd49f4ff7a025379cd0 144 Gene3D G3DSA:3.30.530.20 4 144 3.4E-45 T 13-09-2016 IPR023393 START-like domain THL1_RS24520 3ccd37d5efc8bdd49f4ff7a025379cd0 144 SUPERFAMILY SSF55961 1 144 2.85E-31 T 13-09-2016 THL1_RS24520 3ccd37d5efc8bdd49f4ff7a025379cd0 144 PANTHER PTHR12901 3 144 1.7E-68 T 13-09-2016 THL1_RS04390 00be1a6744643033bbe978e70f9c9a49 159 Gene3D G3DSA:1.10.10.10 5 56 8.8E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS04390 00be1a6744643033bbe978e70f9c9a49 159 SMART SM00344 4 114 3.8E-43 T 13-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 THL1_RS04390 00be1a6744643033bbe978e70f9c9a49 159 Pfam PF01037 Lrp/AsnC ligand binding domain 70 145 5.2E-24 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS04390 00be1a6744643033bbe978e70f9c9a49 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 5.6E-19 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS04390 00be1a6744643033bbe978e70f9c9a49 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 5.6E-19 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS04390 00be1a6744643033bbe978e70f9c9a49 159 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 5.6E-19 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS04390 00be1a6744643033bbe978e70f9c9a49 159 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 5.3E-23 T 13-09-2016 THL1_RS04390 00be1a6744643033bbe978e70f9c9a49 159 PANTHER PTHR30154:SF19 1 158 4.7E-106 T 13-09-2016 THL1_RS04390 00be1a6744643033bbe978e70f9c9a49 159 PANTHER PTHR30154 1 158 4.7E-106 T 13-09-2016 THL1_RS04390 00be1a6744643033bbe978e70f9c9a49 159 Gene3D G3DSA:3.30.70.920 57 142 2.5E-30 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS04390 00be1a6744643033bbe978e70f9c9a49 159 SUPERFAMILY SSF46785 4 94 4.23E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS04390 00be1a6744643033bbe978e70f9c9a49 159 SUPERFAMILY SSF54909 64 154 1.61E-21 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS04390 00be1a6744643033bbe978e70f9c9a49 159 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 13-09-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site THL1_RS11275 ebc5c67e97e0400656da5e9e86183597 253 SUPERFAMILY SSF51735 4 249 3.78E-59 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11275 ebc5c67e97e0400656da5e9e86183597 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 178 0.0011 T 13-09-2016 THL1_RS11275 ebc5c67e97e0400656da5e9e86183597 253 PANTHER PTHR24322 147 179 4.8E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11275 ebc5c67e97e0400656da5e9e86183597 253 PANTHER PTHR24322 6 131 4.8E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11275 ebc5c67e97e0400656da5e9e86183597 253 Pfam PF00106 short chain dehydrogenase 3 188 1.8E-46 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11275 ebc5c67e97e0400656da5e9e86183597 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 7.6E-21 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11275 ebc5c67e97e0400656da5e9e86183597 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 7.6E-21 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11275 ebc5c67e97e0400656da5e9e86183597 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 7.6E-21 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11275 ebc5c67e97e0400656da5e9e86183597 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 7.6E-21 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11275 ebc5c67e97e0400656da5e9e86183597 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 7.6E-21 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11275 ebc5c67e97e0400656da5e9e86183597 253 PANTHER PTHR24322:SF513 147 179 4.8E-42 T 13-09-2016 THL1_RS11275 ebc5c67e97e0400656da5e9e86183597 253 PANTHER PTHR24322:SF513 6 131 4.8E-42 T 13-09-2016 THL1_RS11275 ebc5c67e97e0400656da5e9e86183597 253 Gene3D G3DSA:3.40.50.720 4 247 3.8E-56 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS22135 d49ddfb485fa17db6eb95d3445666eea 249 Pfam PF01709 Transcriptional regulator 5 238 1.5E-93 T 13-09-2016 IPR002876 Transcriptional regulator TACO1-like THL1_RS22135 d49ddfb485fa17db6eb95d3445666eea 249 Gene3D G3DSA:3.30.1270.10 213 248 9.4E-44 T 13-09-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 THL1_RS22135 d49ddfb485fa17db6eb95d3445666eea 249 Gene3D G3DSA:3.30.1270.10 84 134 9.4E-44 T 13-09-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 THL1_RS22135 d49ddfb485fa17db6eb95d3445666eea 249 SUPERFAMILY SSF75625 3 248 6.02E-97 T 13-09-2016 IPR029072 YebC-like THL1_RS22135 d49ddfb485fa17db6eb95d3445666eea 249 Gene3D G3DSA:1.10.10.200 1 79 7.9E-36 T 13-09-2016 IPR017856 Integrase, N-terminal zinc-binding domain-like THL1_RS22135 d49ddfb485fa17db6eb95d3445666eea 249 Gene3D G3DSA:3.30.70.980 135 204 5.0E-28 T 13-09-2016 IPR026564 Transcriptional regulator TACO1-like, domain 3 THL1_RS22135 d49ddfb485fa17db6eb95d3445666eea 249 PANTHER PTHR12532 1 242 9.9E-116 T 13-09-2016 IPR002876 Transcriptional regulator TACO1-like THL1_RS22135 d49ddfb485fa17db6eb95d3445666eea 249 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 239 9.6E-103 T 13-09-2016 IPR002876 Transcriptional regulator TACO1-like THL1_RS22135 d49ddfb485fa17db6eb95d3445666eea 249 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 240 36.607 T 13-09-2016 IPR002876 Transcriptional regulator TACO1-like THL1_RS21370 7ae91bf671179b9cab55d2c7c8ead575 223 Gene3D G3DSA:3.40.50.2300 2 119 3.4E-38 T 13-09-2016 THL1_RS21370 7ae91bf671179b9cab55d2c7c8ead575 223 Pfam PF00072 Response regulator receiver domain 3 112 5.8E-26 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS21370 7ae91bf671179b9cab55d2c7c8ead575 223 PANTHER PTHR26402 1 221 2.3E-83 T 13-09-2016 THL1_RS21370 7ae91bf671179b9cab55d2c7c8ead575 223 Gene3D G3DSA:1.10.10.10 125 220 1.6E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS21370 7ae91bf671179b9cab55d2c7c8ead575 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 218 1.4E-18 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS21370 7ae91bf671179b9cab55d2c7c8ead575 223 SMART SM00448 1 112 5.1E-38 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS21370 7ae91bf671179b9cab55d2c7c8ead575 223 SMART SM00862 145 218 5.9E-19 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS21370 7ae91bf671179b9cab55d2c7c8ead575 223 SUPERFAMILY SSF52172 2 174 1.15E-38 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS21370 7ae91bf671179b9cab55d2c7c8ead575 223 PANTHER PTHR26402:SF316 1 221 2.3E-83 T 13-09-2016 THL1_RS14565 6a79bc1ce063157ce0426eb023109d4d 349 Gene3D G3DSA:3.75.10.10 5 345 2.2E-122 T 13-09-2016 THL1_RS14565 6a79bc1ce063157ce0426eb023109d4d 349 PANTHER PTHR31377 6 348 1.9E-117 T 13-09-2016 THL1_RS14565 6a79bc1ce063157ce0426eb023109d4d 349 PANTHER PTHR31377:SF0 6 348 1.9E-117 T 13-09-2016 THL1_RS14565 6a79bc1ce063157ce0426eb023109d4d 349 SUPERFAMILY SSF55909 5 344 5.71E-117 T 13-09-2016 THL1_RS14565 6a79bc1ce063157ce0426eb023109d4d 349 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 12 343 1.8E-109 T 13-09-2016 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 THL1_RS17390 fcb6b5194aba9baffdf00b42894b5419 385 Gene3D G3DSA:1.20.1090.10 184 384 5.1E-66 T 13-09-2016 THL1_RS17390 fcb6b5194aba9baffdf00b42894b5419 385 SUPERFAMILY SSF56796 7 384 6.28E-119 T 13-09-2016 THL1_RS17390 fcb6b5194aba9baffdf00b42894b5419 385 Gene3D G3DSA:3.40.50.1970 7 183 4.6E-53 T 13-09-2016 THL1_RS17390 fcb6b5194aba9baffdf00b42894b5419 385 PANTHER PTHR11496 6 385 2.9E-136 T 13-09-2016 THL1_RS17390 fcb6b5194aba9baffdf00b42894b5419 385 Pfam PF00465 Iron-containing alcohol dehydrogenase 12 377 1.5E-114 T 13-09-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 THL1_RS17390 fcb6b5194aba9baffdf00b42894b5419 385 PANTHER PTHR11496:SF77 6 385 2.9E-136 T 13-09-2016 THL1_RS17390 fcb6b5194aba9baffdf00b42894b5419 385 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 172 200 - T 13-09-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 THL1_RS13670 d66d8e5e164975ffc978b78575f7a81a 1015 Pfam PF02913 FAD linked oxidases, C-terminal domain 280 534 3.3E-54 T 13-09-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 THL1_RS13670 d66d8e5e164975ffc978b78575f7a81a 1015 Gene3D G3DSA:1.10.1060.10 649 700 2.3E-13 T 13-09-2016 THL1_RS13670 d66d8e5e164975ffc978b78575f7a81a 1015 Gene3D G3DSA:1.10.1060.10 512 615 2.3E-13 T 13-09-2016 THL1_RS13670 d66d8e5e164975ffc978b78575f7a81a 1015 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 668 679 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS13670 d66d8e5e164975ffc978b78575f7a81a 1015 SUPERFAMILY SSF56176 16 281 9.81E-48 T 13-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THL1_RS13670 d66d8e5e164975ffc978b78575f7a81a 1015 PANTHER PTHR11748 13 198 2.4E-139 T 13-09-2016 THL1_RS13670 d66d8e5e164975ffc978b78575f7a81a 1015 PANTHER PTHR11748:SF35 13 198 2.4E-139 T 13-09-2016 THL1_RS13670 d66d8e5e164975ffc978b78575f7a81a 1015 Gene3D G3DSA:3.30.43.10 14 109 3.6E-21 T 13-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 THL1_RS13670 d66d8e5e164975ffc978b78575f7a81a 1015 SUPERFAMILY SSF55103 258 537 4.91E-50 T 13-09-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 THL1_RS13670 d66d8e5e164975ffc978b78575f7a81a 1015 Gene3D G3DSA:3.30.465.10 110 281 9.7E-39 T 13-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THL1_RS13670 d66d8e5e164975ffc978b78575f7a81a 1015 Pfam PF01565 FAD binding domain 52 188 1.8E-33 T 13-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THL1_RS13670 d66d8e5e164975ffc978b78575f7a81a 1015 Pfam PF13183 4Fe-4S dicluster domain 573 682 3.7E-11 T 13-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THL1_RS13670 d66d8e5e164975ffc978b78575f7a81a 1015 PANTHER PTHR11748:SF35 248 583 2.4E-139 T 13-09-2016 THL1_RS13670 d66d8e5e164975ffc978b78575f7a81a 1015 SUPERFAMILY SSF46548 559 618 1.13E-6 T 13-09-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 THL1_RS13670 d66d8e5e164975ffc978b78575f7a81a 1015 SUPERFAMILY SSF46548 650 686 1.13E-6 T 13-09-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 THL1_RS13670 d66d8e5e164975ffc978b78575f7a81a 1015 PANTHER PTHR11748 248 583 2.4E-139 T 13-09-2016 THL1_RS19500 83cbd893c4c3071b771826b789f015e6 262 PIRSF PIRSF002884 25 262 3.7E-91 T 13-09-2016 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 KEGG: 00051+3.1.3.-|KEGG: 00332+3.1.3.-|KEGG: 00565+3.1.3.-|KEGG: 00600+3.1.3.-|KEGG: 00730+3.1.3.-|KEGG: 00740+3.1.3.-|KEGG: 00760+3.1.3.- THL1_RS19500 83cbd893c4c3071b771826b789f015e6 262 PANTHER PTHR22617:SF35 1 262 5.1E-75 T 13-09-2016 THL1_RS19500 83cbd893c4c3071b771826b789f015e6 262 PANTHER PTHR22617 1 262 5.1E-75 T 13-09-2016 THL1_RS19500 83cbd893c4c3071b771826b789f015e6 262 SUPERFAMILY SSF75708 37 261 5.89E-62 T 13-09-2016 THL1_RS19500 83cbd893c4c3071b771826b789f015e6 262 Gene3D G3DSA:1.10.287.500 76 202 1.7E-46 T 13-09-2016 THL1_RS19500 83cbd893c4c3071b771826b789f015e6 262 Pfam PF04344 Chemotaxis phosphatase, CheZ 49 262 2.9E-74 T 13-09-2016 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 KEGG: 00051+3.1.3.-|KEGG: 00332+3.1.3.-|KEGG: 00565+3.1.3.-|KEGG: 00600+3.1.3.-|KEGG: 00730+3.1.3.-|KEGG: 00740+3.1.3.-|KEGG: 00760+3.1.3.- THL1_RS11740 058bb79abae1bf42852c71dda8d60f7e 314 PANTHER PTHR11440 32 147 1.4E-18 T 13-09-2016 THL1_RS11740 058bb79abae1bf42852c71dda8d60f7e 314 Gene3D G3DSA:3.40.50.1820 30 313 2.6E-58 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS11740 058bb79abae1bf42852c71dda8d60f7e 314 Pfam PF00561 alpha/beta hydrolase fold 38 283 3.5E-21 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS11740 058bb79abae1bf42852c71dda8d60f7e 314 SUPERFAMILY SSF53474 33 310 2.39E-51 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS03730 9d4fe14798d0a8e4484b3041da198a8e 240 SUPERFAMILY SSF52833 140 233 3.58E-15 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS03730 9d4fe14798d0a8e4484b3041da198a8e 240 PANTHER PTHR11780 141 234 2.0E-17 T 13-09-2016 THL1_RS03730 9d4fe14798d0a8e4484b3041da198a8e 240 Gene3D G3DSA:3.40.30.10 141 234 1.5E-17 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS03730 9d4fe14798d0a8e4484b3041da198a8e 240 PANTHER PTHR11780:SF12 141 234 2.0E-17 T 13-09-2016 THL1_RS14170 f6b024ea8dd2b40946641106734d7ff5 317 PANTHER PTHR12151 35 138 3.0E-33 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS14170 f6b024ea8dd2b40946641106734d7ff5 317 SUPERFAMILY SSF46626 202 297 1.0E-17 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS14170 f6b024ea8dd2b40946641106734d7ff5 317 Pfam PF00034 Cytochrome c 209 297 5.2E-11 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS14170 f6b024ea8dd2b40946641106734d7ff5 317 SUPERFAMILY SSF52833 30 165 2.92E-35 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS14170 f6b024ea8dd2b40946641106734d7ff5 317 Pfam PF02630 SCO1/SenC 34 143 1.1E-19 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS14170 f6b024ea8dd2b40946641106734d7ff5 317 Gene3D G3DSA:1.10.760.10 205 296 4.4E-16 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS14170 f6b024ea8dd2b40946641106734d7ff5 317 Gene3D G3DSA:3.40.30.10 7 145 7.1E-36 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS16480 de903adc4a0f040192b4e95f5b830ca2 368 SUPERFAMILY SSF53850 38 366 4.24E-59 T 13-09-2016 THL1_RS16480 de903adc4a0f040192b4e95f5b830ca2 368 Gene3D G3DSA:3.40.190.10 146 295 1.6E-28 T 13-09-2016 THL1_RS16480 de903adc4a0f040192b4e95f5b830ca2 368 PANTHER PTHR30222:SF5 1 291 2.4E-49 T 13-09-2016 THL1_RS16480 de903adc4a0f040192b4e95f5b830ca2 368 Pfam PF13416 Bacterial extracellular solute-binding protein 54 290 5.2E-34 T 13-09-2016 THL1_RS16480 de903adc4a0f040192b4e95f5b830ca2 368 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 264 283 2.0E-16 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS16480 de903adc4a0f040192b4e95f5b830ca2 368 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 103 116 2.0E-16 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS16480 de903adc4a0f040192b4e95f5b830ca2 368 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 161 175 2.0E-16 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS16480 de903adc4a0f040192b4e95f5b830ca2 368 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 136 152 2.0E-16 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS16480 de903adc4a0f040192b4e95f5b830ca2 368 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 60 81 2.0E-16 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS16480 de903adc4a0f040192b4e95f5b830ca2 368 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 44 60 2.0E-16 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS16480 de903adc4a0f040192b4e95f5b830ca2 368 PANTHER PTHR30222 1 291 2.4E-49 T 13-09-2016 THL1_RS16480 de903adc4a0f040192b4e95f5b830ca2 368 Gene3D G3DSA:3.40.190.10 38 145 1.4E-21 T 13-09-2016 THL1_RS01670 8c0755f0f1ac94982b0a5cb7d9de5cb6 164 PANTHER PTHR30399:SF4 1 162 2.3E-92 T 13-09-2016 THL1_RS01670 8c0755f0f1ac94982b0a5cb7d9de5cb6 164 Pfam PF01863 Protein of unknown function DUF45 93 154 3.1E-13 T 13-09-2016 IPR002725 Protein of unknown function DUF45 THL1_RS01670 8c0755f0f1ac94982b0a5cb7d9de5cb6 164 PANTHER PTHR30399 1 162 2.3E-92 T 13-09-2016 THL1_RS23605 69f31f65bb972697a98e4d0817937fe0 186 Gene3D G3DSA:1.10.286.10 3 52 2.5E-20 T 13-09-2016 THL1_RS23605 69f31f65bb972697a98e4d0817937fe0 186 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 62 78 - T 13-09-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 THL1_RS23605 69f31f65bb972697a98e4d0817937fe0 186 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 110 120 - T 13-09-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 THL1_RS23605 69f31f65bb972697a98e4d0817937fe0 186 PANTHER PTHR11109 4 186 8.0E-115 T 13-09-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 THL1_RS23605 69f31f65bb972697a98e4d0817937fe0 186 SUPERFAMILY SSF55620 4 184 5.71E-78 T 13-09-2016 THL1_RS23605 69f31f65bb972697a98e4d0817937fe0 186 Gene3D G3DSA:3.30.1130.10 55 184 1.6E-63 T 13-09-2016 THL1_RS23605 69f31f65bb972697a98e4d0817937fe0 186 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 1 183 38.344 T 13-09-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 THL1_RS23605 69f31f65bb972697a98e4d0817937fe0 186 Pfam PF01227 GTP cyclohydrolase I 8 182 2.3E-74 T 13-09-2016 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 THL1_RS23605 69f31f65bb972697a98e4d0817937fe0 186 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 6 184 5.0E-76 T 13-09-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 THL1_RS03475 4d2d2385522a2c5f18f2cbebacd89cd8 231 PANTHER PTHR23105:SF5 21 229 7.1E-74 T 13-09-2016 THL1_RS03475 4d2d2385522a2c5f18f2cbebacd89cd8 231 PIRSF PIRSF002155 1 227 3.1E-72 T 13-09-2016 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 THL1_RS03475 4d2d2385522a2c5f18f2cbebacd89cd8 231 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 41.671 T 13-09-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 THL1_RS03475 4d2d2385522a2c5f18f2cbebacd89cd8 231 Gene3D G3DSA:3.40.50.790 69 159 3.0E-37 T 13-09-2016 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich THL1_RS03475 4d2d2385522a2c5f18f2cbebacd89cd8 231 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 1.4E-101 T 13-09-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 THL1_RS03475 4d2d2385522a2c5f18f2cbebacd89cd8 231 Gene3D G3DSA:3.30.190.20 18 68 2.4E-43 T 13-09-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 THL1_RS03475 4d2d2385522a2c5f18f2cbebacd89cd8 231 Gene3D G3DSA:3.30.190.20 161 225 2.4E-43 T 13-09-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 THL1_RS03475 4d2d2385522a2c5f18f2cbebacd89cd8 231 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 13-09-2016 IPR023673 Ribosomal protein L1, conserved site THL1_RS03475 4d2d2385522a2c5f18f2cbebacd89cd8 231 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 2.5E-48 T 13-09-2016 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein THL1_RS03475 4d2d2385522a2c5f18f2cbebacd89cd8 231 PANTHER PTHR23105 21 229 7.1E-74 T 13-09-2016 THL1_RS03475 4d2d2385522a2c5f18f2cbebacd89cd8 231 SUPERFAMILY SSF56808 6 225 8.89E-77 T 13-09-2016 IPR023674 Ribosomal protein L1-like THL1_RS07380 2441f773788937ea66968e7cfc4d9e56 453 PANTHER PTHR16943:SF8 6 451 5.1E-104 T 13-09-2016 THL1_RS07380 2441f773788937ea66968e7cfc4d9e56 453 SUPERFAMILY SSF103378 4 444 1.44E-111 T 13-09-2016 IPR005656 MmgE/PrpD GO:0016829 THL1_RS07380 2441f773788937ea66968e7cfc4d9e56 453 Gene3D G3DSA:3.30.1330.120 270 377 5.3E-18 T 13-09-2016 THL1_RS07380 2441f773788937ea66968e7cfc4d9e56 453 PANTHER PTHR16943 6 451 5.1E-104 T 13-09-2016 IPR005656 MmgE/PrpD GO:0016829 THL1_RS07380 2441f773788937ea66968e7cfc4d9e56 453 Pfam PF03972 MmgE/PrpD family 6 437 2.5E-117 T 13-09-2016 IPR005656 MmgE/PrpD GO:0016829 THL1_RS12330 7e73aeebb5c1485bfd5c6e49f4849cda 141 Gene3D G3DSA:3.40.630.30 12 138 2.9E-39 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS12330 7e73aeebb5c1485bfd5c6e49f4849cda 141 PANTHER PTHR13355:SF8 17 139 1.1E-27 T 13-09-2016 THL1_RS12330 7e73aeebb5c1485bfd5c6e49f4849cda 141 PANTHER PTHR13355 17 139 1.1E-27 T 13-09-2016 THL1_RS12330 7e73aeebb5c1485bfd5c6e49f4849cda 141 SUPERFAMILY SSF55729 4 139 1.15E-35 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS12330 7e73aeebb5c1485bfd5c6e49f4849cda 141 Pfam PF13673 Acetyltransferase (GNAT) domain 25 139 2.2E-23 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3433 3451 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 TIGRFAM TIGR03661 T1SS_VCA0849: type I secretion C-terminal target domain (VC_A0849 subclass) 3478 3562 3.9E-15 T 13-09-2016 IPR019960 Type I secretion C-terminal target domain, VC_A0849 subclass THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3415 3433 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 SMART SM00112 2560 2639 5.8E-14 T 13-09-2016 IPR002126 Cadherin GO:0005509|GO:0007156|GO:0016020 THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 3424 3442 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 205 294 1.3E-6 T 13-09-2016 IPR010221 VCBS repeat THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 Pfam PF16184 Cadherin-like 543 595 1.2E-8 T 13-09-2016 THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 Pfam PF00028 Cadherin domain 2540 2631 3.7E-11 T 13-09-2016 IPR002126 Cadherin GO:0005509|GO:0007156|GO:0016020 THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 PRINTS PR00313 NodO calcium binding signature 3398 3409 3.6E-6 T 13-09-2016 THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 PRINTS PR00313 NodO calcium binding signature 3437 3446 3.6E-6 T 13-09-2016 THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 PRINTS PR00313 NodO calcium binding signature 3428 3436 3.6E-6 T 13-09-2016 THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 PRINTS PR00313 NodO calcium binding signature 3419 3427 3.6E-6 T 13-09-2016 THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 SUPERFAMILY SSF51120 3370 3528 3.92E-26 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 Gene3D G3DSA:2.60.40.60 2540 2632 1.2E-14 T 13-09-2016 IPR002126 Cadherin GO:0005509|GO:0007156|GO:0016020 THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 SUPERFAMILY SSF49313 2541 2633 3.01E-13 T 13-09-2016 IPR015919 Cadherin-like GO:0005509|GO:0016020 THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3445 3461 0.14 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3410 3426 1.5 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 3427 3444 0.012 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS21460 01eaf78d159376266ac98910277e06dc 3575 SUPERFAMILY SSF49313 195 278 3.53E-5 T 13-09-2016 IPR015919 Cadherin-like GO:0005509|GO:0016020 THL1_RS07830 3ab1bafae2f27e6548e3b4af656406ec 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 2.9E-15 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS07830 3ab1bafae2f27e6548e3b4af656406ec 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 2.9E-15 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS07830 3ab1bafae2f27e6548e3b4af656406ec 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 2.9E-15 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS07830 3ab1bafae2f27e6548e3b4af656406ec 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 2.9E-15 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS07830 3ab1bafae2f27e6548e3b4af656406ec 292 PIRSF PIRSF001365 1 292 6.6E-82 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS07830 3ab1bafae2f27e6548e3b4af656406ec 292 SUPERFAMILY SSF51569 2 289 9.21E-86 T 13-09-2016 THL1_RS07830 3ab1bafae2f27e6548e3b4af656406ec 292 PANTHER PTHR12128:SF34 1 288 1.7E-84 T 13-09-2016 THL1_RS07830 3ab1bafae2f27e6548e3b4af656406ec 292 PANTHER PTHR12128 1 288 1.7E-84 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS07830 3ab1bafae2f27e6548e3b4af656406ec 292 SMART SM01130 2 291 4.9E-94 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS07830 3ab1bafae2f27e6548e3b4af656406ec 292 Gene3D G3DSA:3.20.20.70 1 290 6.1E-91 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS07830 3ab1bafae2f27e6548e3b4af656406ec 292 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 6 288 9.3E-64 T 13-09-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS07830 3ab1bafae2f27e6548e3b4af656406ec 292 Pfam PF00701 Dihydrodipicolinate synthetase family 3 288 1.6E-66 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS12280 fe3434917ff3f0b26e3ce91b7e3d3e79 448 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 63 235 6.6E-52 T 13-09-2016 IPR011538 NADH-ubiquinone oxidoreductase 51 kDa subunit, FMN-binding domain THL1_RS12280 fe3434917ff3f0b26e3ce91b7e3d3e79 448 PANTHER PTHR11780 21 436 1.5E-214 T 13-09-2016 THL1_RS12280 fe3434917ff3f0b26e3ce91b7e3d3e79 448 SUPERFAMILY SSF142984 259 342 7.45E-20 T 13-09-2016 THL1_RS12280 fe3434917ff3f0b26e3ce91b7e3d3e79 448 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 360 371 - T 13-09-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 THL1_RS12280 fe3434917ff3f0b26e3ce91b7e3d3e79 448 SUPERFAMILY SSF140490 344 438 7.32E-30 T 13-09-2016 THL1_RS12280 fe3434917ff3f0b26e3ce91b7e3d3e79 448 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 22 434 2.6E-196 T 13-09-2016 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 THL1_RS12280 fe3434917ff3f0b26e3ce91b7e3d3e79 448 SMART SM00928 347 392 2.8E-21 T 13-09-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 THL1_RS12280 fe3434917ff3f0b26e3ce91b7e3d3e79 448 SUPERFAMILY SSF142019 29 254 3.01E-86 T 13-09-2016 THL1_RS12280 fe3434917ff3f0b26e3ce91b7e3d3e79 448 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 350 432 6.2E-24 T 13-09-2016 IPR019575 NADH-ubiquinone oxidoreductase 51 kDa subunit, iron-sulphur binding domain GO:0051539 THL1_RS12280 fe3434917ff3f0b26e3ce91b7e3d3e79 448 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 183 198 - T 13-09-2016 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SMART SM00091 30 98 0.022 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SMART SM00091 408 476 0.065 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SMART SM00091 158 225 7.3E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SMART SM00091 537 604 6.7E-9 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SMART SM00091 283 350 5.1E-12 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SMART SM00091 662 728 2.6E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SUPERFAMILY SSF55785 647 773 9.07E-24 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 782 951 2.4E-45 T 13-09-2016 IPR000160 GGDEF domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SUPERFAMILY SSF55785 269 394 1.92E-24 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 Pfam PF08447 PAS fold 431 518 5.8E-14 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 Pfam PF08447 PAS fold 53 140 1.5E-11 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SMART SM00086 483 525 4.3E-4 T 13-09-2016 IPR001610 PAC motif THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SMART SM00086 356 396 10.0 T 13-09-2016 IPR001610 PAC motif THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SMART SM00086 735 775 6.0 T 13-09-2016 IPR001610 PAC motif THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SMART SM00086 610 650 10.0 T 13-09-2016 IPR001610 PAC motif THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SMART SM00086 231 271 9.5 T 13-09-2016 IPR001610 PAC motif THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SMART SM00086 105 146 0.27 T 13-09-2016 IPR001610 PAC motif THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SUPERFAMILY SSF55785 522 648 5.93E-23 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 Pfam PF13188 PAS domain 158 203 4.4E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SUPERFAMILY SSF55073 791 953 7.85E-48 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 Gene3D G3DSA:3.30.450.20 400 522 1.3E-25 T 13-09-2016 THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 Gene3D G3DSA:3.30.450.20 34 143 1.9E-17 T 13-09-2016 THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 281 403 7.4E-17 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 534 657 9.0E-17 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 404 532 2.6E-13 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 44 153 1.8E-10 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 156 278 6.9E-14 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 659 781 8.2E-18 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 Pfam PF00990 Diguanylate cyclase, GGDEF domain 786 947 1.9E-49 T 13-09-2016 IPR000160 GGDEF domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 Gene3D G3DSA:3.30.450.20 144 267 2.5E-16 T 13-09-2016 THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 Gene3D G3DSA:3.30.450.20 268 394 1.4E-25 T 13-09-2016 THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 Gene3D G3DSA:3.30.450.20 523 647 2.1E-23 T 13-09-2016 THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 Gene3D G3DSA:3.30.450.20 648 773 3.8E-26 T 13-09-2016 THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 Gene3D G3DSA:3.20.20.450 965 1218 1.0E-96 T 13-09-2016 IPR001633 EAL domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SMART SM00267 775 952 4.3E-66 T 13-09-2016 IPR000160 GGDEF domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 PANTHER PTHR33121 941 1222 1.9E-84 T 13-09-2016 THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SUPERFAMILY SSF55785 143 269 1.62E-17 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SUPERFAMILY SSF55785 42 153 2.44E-17 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 Pfam PF00563 EAL domain 968 1206 1.8E-72 T 13-09-2016 IPR001633 EAL domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 Pfam PF00989 PAS fold 538 647 1.1E-9 T 13-09-2016 IPR013767 PAS fold GO:0006355 THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 Pfam PF00989 PAS fold 284 392 1.5E-9 T 13-09-2016 IPR013767 PAS fold GO:0006355 THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SUPERFAMILY SSF141868 967 1218 1.57E-90 T 13-09-2016 IPR001633 EAL domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SMART SM00052 962 1211 5.7E-117 T 13-09-2016 IPR001633 EAL domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 Gene3D G3DSA:3.30.70.270 787 960 6.2E-59 T 13-09-2016 THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 PANTHER PTHR33121:SF13 941 1222 1.9E-84 T 13-09-2016 THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 Pfam PF13426 PAS domain 672 773 2.5E-9 T 13-09-2016 IPR000014 PAS domain THL1_RS10005 11186fa1ec6735784287374a1396e85e 1226 SUPERFAMILY SSF55785 393 523 4.36E-18 T 13-09-2016 IPR000014 PAS domain THL1_RS26475 e437abfebbb33372bb40f44accf946a8 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 136 317 8.3E-26 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS26475 e437abfebbb33372bb40f44accf946a8 320 SUPERFAMILY SSF161098 117 302 3.66E-47 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS26475 e437abfebbb33372bb40f44accf946a8 320 PANTHER PTHR30614 6 320 8.1E-129 T 13-09-2016 THL1_RS26475 e437abfebbb33372bb40f44accf946a8 320 PANTHER PTHR30614:SF0 6 320 8.1E-129 T 13-09-2016 THL1_RS26475 e437abfebbb33372bb40f44accf946a8 320 Gene3D G3DSA:1.10.3720.10 115 316 5.2E-53 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS26475 e437abfebbb33372bb40f44accf946a8 320 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 117 211 4.2E-27 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS27910 d3a29fe7c226838fdd566e7e5f16875a 266 SMART SM00342 179 261 2.4E-23 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS27910 d3a29fe7c226838fdd566e7e5f16875a 266 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 245 261 4.6E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS27910 d3a29fe7c226838fdd566e7e5f16875a 266 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 230 245 4.6E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS27910 d3a29fe7c226838fdd566e7e5f16875a 266 SUPERFAMILY SSF51215 22 132 2.09E-16 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS27910 d3a29fe7c226838fdd566e7e5f16875a 266 PANTHER PTHR11019 1 265 1.1E-77 T 13-09-2016 THL1_RS27910 d3a29fe7c226838fdd566e7e5f16875a 266 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 216 257 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS27910 d3a29fe7c226838fdd566e7e5f16875a 266 Gene3D G3DSA:1.10.10.60 217 263 2.4E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS27910 d3a29fe7c226838fdd566e7e5f16875a 266 SUPERFAMILY SSF46689 215 263 3.49E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS27910 d3a29fe7c226838fdd566e7e5f16875a 266 SUPERFAMILY SSF46689 167 213 2.51E-7 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS27910 d3a29fe7c226838fdd566e7e5f16875a 266 Gene3D G3DSA:2.60.120.280 21 129 2.0E-11 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS27910 d3a29fe7c226838fdd566e7e5f16875a 266 Gene3D G3DSA:1.10.10.60 168 216 5.6E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS27910 d3a29fe7c226838fdd566e7e5f16875a 266 Pfam PF12833 Helix-turn-helix domain 185 262 1.4E-20 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS27910 d3a29fe7c226838fdd566e7e5f16875a 266 Pfam PF02311 AraC-like ligand binding domain 13 140 2.8E-22 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS27910 d3a29fe7c226838fdd566e7e5f16875a 266 PANTHER PTHR11019:SF139 1 265 1.1E-77 T 13-09-2016 THL1_RS06035 cacca378b9e3432da336b285810aab97 273 PANTHER PTHR21666 62 268 3.4E-38 T 13-09-2016 THL1_RS06035 cacca378b9e3432da336b285810aab97 273 SUPERFAMILY SSF51261 126 268 4.71E-47 T 13-09-2016 IPR011055 Duplicated hybrid motif THL1_RS06035 cacca378b9e3432da336b285810aab97 273 Gene3D G3DSA:2.70.70.10 122 269 9.6E-43 T 13-09-2016 THL1_RS06035 cacca378b9e3432da336b285810aab97 273 Pfam PF01551 Peptidase family M23 170 264 5.7E-27 T 13-09-2016 IPR016047 Peptidase M23 THL1_RS06035 cacca378b9e3432da336b285810aab97 273 Gene3D G3DSA:2.60.40.1590 20 114 2.3E-36 T 13-09-2016 THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 SUPERFAMILY SSF51735 2 150 6.9E-33 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 Pfam PF02080 TrkA-C domain 156 224 4.8E-12 T 13-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 Pfam PF02080 TrkA-C domain 389 450 3.4E-12 T 13-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 SUPERFAMILY SSF116726 135 222 3.01E-11 T 13-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 Gene3D G3DSA:3.30.70.1450 389 435 7.9E-6 T 13-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 SUPERFAMILY SSF116726 361 436 3.53E-9 T 13-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 Pfam PF02254 TrkA-N domain 3 111 7.2E-26 T 13-09-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 Pfam PF02254 TrkA-N domain 234 349 1.5E-23 T 13-09-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 PANTHER PTHR13789 2 169 2.3E-95 T 13-09-2016 THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 PANTHER PTHR13789 415 452 2.3E-95 T 13-09-2016 THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 Gene3D G3DSA:3.30.70.1450 157 224 6.9E-5 T 13-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 3.0E-30 T 13-09-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 3.0E-30 T 13-09-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 3.0E-30 T 13-09-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 3.0E-30 T 13-09-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 3.0E-30 T 13-09-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 SUPERFAMILY SSF51735 232 375 3.07E-33 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 Gene3D G3DSA:3.40.50.720 232 375 4.2E-37 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 Gene3D G3DSA:3.40.50.720 2 151 7.8E-46 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 PANTHER PTHR13789:SF225 2 169 2.3E-95 T 13-09-2016 THL1_RS00090 4630f29e9098b8292fd4d28c0103693f 457 PANTHER PTHR13789:SF225 415 452 2.3E-95 T 13-09-2016 THL1_RS17870 4c86463a33779f187cc2b63cccb76021 198 PANTHER PTHR30055 3 189 1.9E-26 T 13-09-2016 THL1_RS17870 4c86463a33779f187cc2b63cccb76021 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 6 50 1.4E-14 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS17870 4c86463a33779f187cc2b63cccb76021 198 Gene3D G3DSA:1.10.357.10 48 189 1.1E-20 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS17870 4c86463a33779f187cc2b63cccb76021 198 Gene3D G3DSA:1.10.10.60 3 47 1.5E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17870 4c86463a33779f187cc2b63cccb76021 198 SUPERFAMILY SSF46689 2 60 3.45E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17870 4c86463a33779f187cc2b63cccb76021 198 PANTHER PTHR30055:SF10 3 189 1.9E-26 T 13-09-2016 THL1_RS17870 4c86463a33779f187cc2b63cccb76021 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 50 4.1E-8 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS17870 4c86463a33779f187cc2b63cccb76021 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 6 19 4.1E-8 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS12705 e33f8155fbfe2bf7a30b1d20c2794250 147 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 5 139 4.2E-61 T 13-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS12705 e33f8155fbfe2bf7a30b1d20c2794250 147 PANTHER PTHR21272 1 146 7.9E-88 T 13-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS12705 e33f8155fbfe2bf7a30b1d20c2794250 147 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 147 74.084 T 13-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS12705 e33f8155fbfe2bf7a30b1d20c2794250 147 PIRSF PIRSF001399 1 146 1.0E-63 T 13-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS12705 e33f8155fbfe2bf7a30b1d20c2794250 147 ProSitePatterns PS01029 Dehydroquinase class II signature. 8 25 - T 13-09-2016 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS12705 e33f8155fbfe2bf7a30b1d20c2794250 147 SUPERFAMILY SSF52304 4 145 3.27E-63 T 13-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS12705 e33f8155fbfe2bf7a30b1d20c2794250 147 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 5 146 1.0E-57 T 13-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS12705 e33f8155fbfe2bf7a30b1d20c2794250 147 Gene3D G3DSA:3.40.50.9100 2 143 5.5E-67 T 13-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS12705 e33f8155fbfe2bf7a30b1d20c2794250 147 Pfam PF01220 Dehydroquinase class II 5 139 2.8E-60 T 13-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS25205 bcf103569b442bfa9cbaa8b0a2db5fa4 162 Pfam PF00583 Acetyltransferase (GNAT) family 59 136 5.7E-13 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS25205 bcf103569b442bfa9cbaa8b0a2db5fa4 162 PANTHER PTHR23091:SF250 8 160 3.3E-65 T 13-09-2016 THL1_RS25205 bcf103569b442bfa9cbaa8b0a2db5fa4 162 Gene3D G3DSA:3.40.630.30 6 160 3.9E-39 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS25205 bcf103569b442bfa9cbaa8b0a2db5fa4 162 SUPERFAMILY SSF55729 5 160 3.9E-34 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS25205 bcf103569b442bfa9cbaa8b0a2db5fa4 162 PANTHER PTHR23091 8 160 3.3E-65 T 13-09-2016 THL1_RS00130 23aa97cb9682e6aaa5c4dfb37ecba8e1 306 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 165 189 - T 13-09-2016 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS00130 23aa97cb9682e6aaa5c4dfb37ecba8e1 306 PRINTS PR00073 Coprogen oxidase signature 89 113 2.3E-85 T 13-09-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS00130 23aa97cb9682e6aaa5c4dfb37ecba8e1 306 PRINTS PR00073 Coprogen oxidase signature 30 46 2.3E-85 T 13-09-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS00130 23aa97cb9682e6aaa5c4dfb37ecba8e1 306 PRINTS PR00073 Coprogen oxidase signature 161 190 2.3E-85 T 13-09-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS00130 23aa97cb9682e6aaa5c4dfb37ecba8e1 306 PRINTS PR00073 Coprogen oxidase signature 261 287 2.3E-85 T 13-09-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS00130 23aa97cb9682e6aaa5c4dfb37ecba8e1 306 PRINTS PR00073 Coprogen oxidase signature 233 260 2.3E-85 T 13-09-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS00130 23aa97cb9682e6aaa5c4dfb37ecba8e1 306 PRINTS PR00073 Coprogen oxidase signature 47 68 2.3E-85 T 13-09-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS00130 23aa97cb9682e6aaa5c4dfb37ecba8e1 306 PRINTS PR00073 Coprogen oxidase signature 124 146 2.3E-85 T 13-09-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS00130 23aa97cb9682e6aaa5c4dfb37ecba8e1 306 PIRSF PIRSF000166 1 302 5.9E-126 T 13-09-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS00130 23aa97cb9682e6aaa5c4dfb37ecba8e1 306 SUPERFAMILY SSF102886 4 301 9.68E-138 T 13-09-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS00130 23aa97cb9682e6aaa5c4dfb37ecba8e1 306 Pfam PF01218 Coproporphyrinogen III oxidase 8 301 1.5E-130 T 13-09-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS00130 23aa97cb9682e6aaa5c4dfb37ecba8e1 306 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 2 276 55.289 T 13-09-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS00130 23aa97cb9682e6aaa5c4dfb37ecba8e1 306 Gene3D G3DSA:3.40.1500.10 4 301 3.3E-134 T 13-09-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS00130 23aa97cb9682e6aaa5c4dfb37ecba8e1 306 PANTHER PTHR10755 3 302 1.0E-186 T 13-09-2016 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-5531|MetaCyc: PWY-7159|UniPathway: UPA00251 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 SUPERFAMILY SSF50249 616 695 8.21E-23 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 Gene3D G3DSA:1.10.10.400 240 314 6.5E-22 T 13-09-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 Gene3D G3DSA:2.40.50.140 625 695 2.5E-25 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 SUPERFAMILY SSF55666 145 235 2.24E-26 T 13-09-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 243 322 9.1E-24 T 13-09-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 Pfam PF01138 3' exoribonuclease family, domain 1 326 458 1.1E-21 T 13-09-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 Pfam PF01138 3' exoribonuclease family, domain 1 15 144 6.2E-20 T 13-09-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 Pfam PF00013 KH domain 560 614 2.9E-13 T 13-09-2016 IPR004088 K Homology domain, type 1 GO:0003723 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 SMART SM00316 622 692 3.5E-25 T 13-09-2016 IPR022967 RNA-binding domain, S1 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 PANTHER PTHR11252:SF0 2 700 0.0 T 13-09-2016 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 Gene3D G3DSA:3.30.230.70 3 226 1.0E-80 T 13-09-2016 IPR027408 PNPase/RNase PH domain THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 Gene3D G3DSA:3.30.230.70 315 545 9.1E-91 T 13-09-2016 IPR027408 PNPase/RNase PH domain THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 Pfam PF00575 S1 RNA binding domain 621 692 3.3E-18 T 13-09-2016 IPR003029 S1 domain GO:0003676 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 Gene3D G3DSA:3.30.1370.10 554 624 9.0E-25 T 13-09-2016 IPR004088 K Homology domain, type 1 GO:0003723 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 9 694 0.0 T 13-09-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 Pfam PF03725 3' exoribonuclease family, domain 2 461 530 1.5E-6 T 13-09-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 Pfam PF03725 3' exoribonuclease family, domain 2 147 211 1.7E-10 T 13-09-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 SMART SM00322 554 619 1.1E-13 T 13-09-2016 IPR004087 K Homology domain GO:0003676 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 SUPERFAMILY SSF54211 4 144 6.58E-48 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 SUPERFAMILY SSF54791 557 642 3.5E-24 T 13-09-2016 IPR004088 K Homology domain, type 1 GO:0003723 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 SUPERFAMILY SSF54211 295 490 1.27E-48 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 2 695 30.25 T 13-09-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 PANTHER PTHR11252 2 700 0.0 T 13-09-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 SUPERFAMILY SSF55666 452 550 4.91E-29 T 13-09-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 THL1_RS24375 d257dbc967719fcd880a51ee0d700eb3 702 PIRSF PIRSF005499 1 701 2.6E-291 T 13-09-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THL1_RS16455 6e2484f6a964e5295a98a00478cf926e 323 PANTHER PTHR30349 14 296 7.9E-16 T 13-09-2016 THL1_RS16455 6e2484f6a964e5295a98a00478cf926e 323 PANTHER PTHR30349:SF34 14 296 7.9E-16 T 13-09-2016 THL1_RS16455 6e2484f6a964e5295a98a00478cf926e 323 SUPERFAMILY SSF47823 7 96 1.59E-25 T 13-09-2016 IPR010998 Integrase, Lambda-type, N-terminal THL1_RS16455 6e2484f6a964e5295a98a00478cf926e 323 Gene3D G3DSA:1.10.150.130 7 99 4.3E-25 T 13-09-2016 IPR023109 Integrase/recombinase, N-terminal THL1_RS16455 6e2484f6a964e5295a98a00478cf926e 323 Gene3D G3DSA:1.10.443.10 100 295 5.5E-54 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS16455 6e2484f6a964e5295a98a00478cf926e 323 Pfam PF00589 Phage integrase family 137 297 2.8E-13 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS16455 6e2484f6a964e5295a98a00478cf926e 323 SUPERFAMILY SSF56349 121 299 1.71E-40 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS01230 f29e081bf4b529fabec569245f39afce 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 3.1E-23 T 13-09-2016 IPR010035 ThiS, thiamine-biosynthesis THL1_RS01230 f29e081bf4b529fabec569245f39afce 66 PANTHER PTHR34472:SF1 1 66 1.9E-25 T 13-09-2016 THL1_RS01230 f29e081bf4b529fabec569245f39afce 66 Pfam PF02597 ThiS family 3 66 1.9E-16 T 13-09-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 THL1_RS01230 f29e081bf4b529fabec569245f39afce 66 PANTHER PTHR34472 1 66 1.9E-25 T 13-09-2016 THL1_RS01230 f29e081bf4b529fabec569245f39afce 66 SUPERFAMILY SSF54285 2 65 4.45E-19 T 13-09-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp THL1_RS01230 f29e081bf4b529fabec569245f39afce 66 Gene3D G3DSA:3.10.20.30 1 66 1.4E-28 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS03280 619b005655f5928e74f1c5620ada38ff 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 210 1.1E-18 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS03280 619b005655f5928e74f1c5620ada38ff 215 SUPERFAMILY SSF161098 10 195 5.76E-37 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS03280 619b005655f5928e74f1c5620ada38ff 215 PANTHER PTHR30614 1 215 4.7E-58 T 13-09-2016 THL1_RS03280 619b005655f5928e74f1c5620ada38ff 215 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 104 1.0E-22 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS03280 619b005655f5928e74f1c5620ada38ff 215 Gene3D G3DSA:1.10.3720.10 9 210 2.9E-36 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS05365 cdaa0999de89de18c43c6198e5cf9614 498 Pfam PF04552 Sigma-54, DNA binding domain 338 496 7.3E-72 T 13-09-2016 IPR007634 RNA polymerase sigma factor 54, DNA-binding THL1_RS05365 cdaa0999de89de18c43c6198e5cf9614 498 PRINTS PR00045 Sigma-54 factor signature 471 489 3.6E-32 T 13-09-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THL1_RS05365 cdaa0999de89de18c43c6198e5cf9614 498 PRINTS PR00045 Sigma-54 factor signature 397 409 3.6E-32 T 13-09-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THL1_RS05365 cdaa0999de89de18c43c6198e5cf9614 498 PRINTS PR00045 Sigma-54 factor signature 207 224 3.6E-32 T 13-09-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THL1_RS05365 cdaa0999de89de18c43c6198e5cf9614 498 PRINTS PR00045 Sigma-54 factor signature 413 424 3.6E-32 T 13-09-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THL1_RS05365 cdaa0999de89de18c43c6198e5cf9614 498 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 385 404 - T 13-09-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THL1_RS05365 cdaa0999de89de18c43c6198e5cf9614 498 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 495 1.3E-155 T 13-09-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THL1_RS05365 cdaa0999de89de18c43c6198e5cf9614 498 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 476 483 - T 13-09-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THL1_RS05365 cdaa0999de89de18c43c6198e5cf9614 498 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 5 48 5.3E-17 T 13-09-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THL1_RS05365 cdaa0999de89de18c43c6198e5cf9614 498 PANTHER PTHR32248 80 498 8.4E-176 T 13-09-2016 THL1_RS05365 cdaa0999de89de18c43c6198e5cf9614 498 PANTHER PTHR32248 1 62 8.4E-176 T 13-09-2016 THL1_RS05365 cdaa0999de89de18c43c6198e5cf9614 498 PANTHER PTHR32248:SF4 80 498 8.4E-176 T 13-09-2016 THL1_RS05365 cdaa0999de89de18c43c6198e5cf9614 498 PANTHER PTHR32248:SF4 1 62 8.4E-176 T 13-09-2016 THL1_RS05365 cdaa0999de89de18c43c6198e5cf9614 498 PIRSF PIRSF000774 1 498 2.4E-155 T 13-09-2016 IPR000394 RNA polymerase sigma factor 54 GO:0003677|GO:0003700|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THL1_RS05365 cdaa0999de89de18c43c6198e5cf9614 498 Pfam PF04963 Sigma-54 factor, core binding domain 131 324 1.1E-61 T 13-09-2016 IPR007046 RNA polymerase sigma factor 54, core-binding GO:0003677|GO:0006352 THL1_RS05025 d95d1806283d2100dc5d0ac6b0958c24 432 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 1.4E-14 T 13-09-2016 THL1_RS05025 d95d1806283d2100dc5d0ac6b0958c24 432 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 1.4E-14 T 13-09-2016 THL1_RS05025 d95d1806283d2100dc5d0ac6b0958c24 432 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 1.4E-14 T 13-09-2016 THL1_RS05025 d95d1806283d2100dc5d0ac6b0958c24 432 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.4E-14 T 13-09-2016 THL1_RS05025 d95d1806283d2100dc5d0ac6b0958c24 432 Gene3D G3DSA:3.50.50.60 119 342 6.6E-33 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS05025 d95d1806283d2100dc5d0ac6b0958c24 432 PANTHER PTHR22912 205 317 2.9E-22 T 13-09-2016 THL1_RS05025 d95d1806283d2100dc5d0ac6b0958c24 432 PANTHER PTHR22912 3 189 2.9E-22 T 13-09-2016 THL1_RS05025 d95d1806283d2100dc5d0ac6b0958c24 432 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 337 2.3E-60 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS05025 d95d1806283d2100dc5d0ac6b0958c24 432 Gene3D G3DSA:3.50.50.60 2 118 1.3E-18 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS05025 d95d1806283d2100dc5d0ac6b0958c24 432 SUPERFAMILY SSF51905 2 335 3.03E-28 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS05025 d95d1806283d2100dc5d0ac6b0958c24 432 PANTHER PTHR22912:SF180 205 317 2.9E-22 T 13-09-2016 THL1_RS05025 d95d1806283d2100dc5d0ac6b0958c24 432 PANTHER PTHR22912:SF180 3 189 2.9E-22 T 13-09-2016 THL1_RS05025 d95d1806283d2100dc5d0ac6b0958c24 432 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 3.9E-8 T 13-09-2016 THL1_RS05025 d95d1806283d2100dc5d0ac6b0958c24 432 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 307 314 3.9E-8 T 13-09-2016 THL1_RS05025 d95d1806283d2100dc5d0ac6b0958c24 432 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 3.9E-8 T 13-09-2016 THL1_RS28230 79d16bf1a64d72025e1817785ac2babe 288 ProSitePatterns PS00356 LacI-type HTH domain signature. 37 55 - T 13-09-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 THL1_RS28230 79d16bf1a64d72025e1817785ac2babe 288 Pfam PF01380 SIS domain 126 252 2.5E-16 T 13-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 THL1_RS28230 79d16bf1a64d72025e1817785ac2babe 288 SUPERFAMILY SSF46689 2 76 5.02E-18 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS28230 79d16bf1a64d72025e1817785ac2babe 288 PANTHER PTHR30514:SF1 1 278 3.1E-94 T 13-09-2016 THL1_RS28230 79d16bf1a64d72025e1817785ac2babe 288 PANTHER PTHR30514 1 278 3.1E-94 T 13-09-2016 THL1_RS28230 79d16bf1a64d72025e1817785ac2babe 288 Gene3D G3DSA:3.40.50.10490 97 262 2.3E-31 T 13-09-2016 THL1_RS28230 79d16bf1a64d72025e1817785ac2babe 288 Pfam PF01418 Helix-turn-helix domain, rpiR family 2 76 1.5E-21 T 13-09-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 THL1_RS28230 79d16bf1a64d72025e1817785ac2babe 288 Gene3D G3DSA:1.10.10.10 2 77 4.0E-27 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS28230 79d16bf1a64d72025e1817785ac2babe 288 SUPERFAMILY SSF53697 85 278 1.98E-36 T 13-09-2016 THL1_RS18410 631c2dce4f5f41140127ab7d13fe62ba 274 PANTHER PTHR24322:SF554 163 194 1.7E-78 T 13-09-2016 THL1_RS18410 631c2dce4f5f41140127ab7d13fe62ba 274 SUPERFAMILY SSF51735 1 244 6.98E-55 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18410 631c2dce4f5f41140127ab7d13fe62ba 274 PANTHER PTHR24322 163 194 1.7E-78 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18410 631c2dce4f5f41140127ab7d13fe62ba 274 PANTHER PTHR24322:SF554 10 145 1.7E-78 T 13-09-2016 THL1_RS18410 631c2dce4f5f41140127ab7d13fe62ba 274 PANTHER PTHR24322 10 145 1.7E-78 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18410 631c2dce4f5f41140127ab7d13fe62ba 274 Gene3D G3DSA:3.40.50.720 1 247 2.5E-55 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18410 631c2dce4f5f41140127ab7d13fe62ba 274 Pfam PF00106 short chain dehydrogenase 6 196 1.9E-39 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18410 631c2dce4f5f41140127ab7d13fe62ba 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 5.7E-6 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18410 631c2dce4f5f41140127ab7d13fe62ba 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 5.7E-6 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18410 631c2dce4f5f41140127ab7d13fe62ba 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 5.7E-6 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18410 631c2dce4f5f41140127ab7d13fe62ba 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.7E-16 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18410 631c2dce4f5f41140127ab7d13fe62ba 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.7E-16 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18410 631c2dce4f5f41140127ab7d13fe62ba 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.7E-16 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18410 631c2dce4f5f41140127ab7d13fe62ba 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 1.7E-16 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18410 631c2dce4f5f41140127ab7d13fe62ba 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 1.7E-16 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18410 631c2dce4f5f41140127ab7d13fe62ba 274 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS19965 846d5d7ebb1071fdb6d25b42ae22b17a 218 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 109 195 4.2E-16 T 13-09-2016 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 THL1_RS19965 846d5d7ebb1071fdb6d25b42ae22b17a 218 PANTHER PTHR12714 75 218 1.1E-29 T 13-09-2016 THL1_RS01805 5afbbe05cb9f29419206ded22af443d6 325 PANTHER PTHR10443 9 251 4.6E-186 T 13-09-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 THL1_RS01805 5afbbe05cb9f29419206ded22af443d6 325 PANTHER PTHR10443 276 323 4.6E-186 T 13-09-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 THL1_RS01805 5afbbe05cb9f29419206ded22af443d6 325 SUPERFAMILY SSF51556 9 324 4.16E-82 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS01805 5afbbe05cb9f29419206ded22af443d6 325 Gene3D G3DSA:3.20.20.140 5 324 6.7E-97 T 13-09-2016 THL1_RS01805 5afbbe05cb9f29419206ded22af443d6 325 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 6 320 1.9E-93 T 13-09-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 THL1_RS01805 5afbbe05cb9f29419206ded22af443d6 325 PANTHER PTHR10443:SF24 9 251 4.6E-186 T 13-09-2016 THL1_RS01805 5afbbe05cb9f29419206ded22af443d6 325 PANTHER PTHR10443:SF24 276 323 4.6E-186 T 13-09-2016 THL1_RS03775 625859ffd75dc30d8fa5e0171710668c 256 Gene3D G3DSA:3.30.950.10 110 230 6.1E-39 T 13-09-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 THL1_RS03775 625859ffd75dc30d8fa5e0171710668c 256 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 206 1.0E-45 T 13-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 THL1_RS03775 625859ffd75dc30d8fa5e0171710668c 256 PANTHER PTHR21091 1 210 1.0E-63 T 13-09-2016 THL1_RS03775 625859ffd75dc30d8fa5e0171710668c 256 PANTHER PTHR21091:SF17 1 210 1.0E-63 T 13-09-2016 THL1_RS03775 625859ffd75dc30d8fa5e0171710668c 256 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 13-09-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 THL1_RS03775 625859ffd75dc30d8fa5e0171710668c 256 Gene3D G3DSA:3.40.1010.10 2 109 2.1E-32 T 13-09-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 THL1_RS03775 625859ffd75dc30d8fa5e0171710668c 256 SUPERFAMILY SSF53790 2 244 4.71E-66 T 13-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 THL1_RS03775 625859ffd75dc30d8fa5e0171710668c 256 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 247 4.1E-94 T 13-09-2016 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 THL1_RS04210 49983909582d6a3589c4642458866a12 421 PANTHER PTHR11063 1 420 2.5E-186 T 13-09-2016 THL1_RS04210 49983909582d6a3589c4642458866a12 421 PIRSF PIRSF000151 1 421 1.6E-181 T 13-09-2016 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 THL1_RS04210 49983909582d6a3589c4642458866a12 421 Gene3D G3DSA:3.40.309.10 229 378 8.2E-41 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS04210 49983909582d6a3589c4642458866a12 421 PANTHER PTHR11063:SF8 1 420 2.5E-186 T 13-09-2016 THL1_RS04210 49983909582d6a3589c4642458866a12 421 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 327 349 - T 13-09-2016 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 THL1_RS04210 49983909582d6a3589c4642458866a12 421 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 16 410 1.6E-157 T 13-09-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 THL1_RS04210 49983909582d6a3589c4642458866a12 421 Gene3D G3DSA:3.40.605.10 379 420 9.0E-106 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS04210 49983909582d6a3589c4642458866a12 421 Gene3D G3DSA:3.40.605.10 3 227 9.0E-106 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS04210 49983909582d6a3589c4642458866a12 421 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 8 420 42.602 T 13-09-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 THL1_RS04210 49983909582d6a3589c4642458866a12 421 Pfam PF00171 Aldehyde dehydrogenase family 14 283 9.9E-14 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS04210 49983909582d6a3589c4642458866a12 421 Pfam PF00171 Aldehyde dehydrogenase family 312 377 3.8E-6 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS04210 49983909582d6a3589c4642458866a12 421 SUPERFAMILY SSF53720 8 420 1.02E-121 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS09385 21372ded6935ffa60dfbe9434b676005 144 SUPERFAMILY SSF46785 7 142 1.2E-29 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09385 21372ded6935ffa60dfbe9434b676005 144 SMART SM00347 26 127 9.7E-21 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS09385 21372ded6935ffa60dfbe9434b676005 144 PANTHER PTHR33164:SF16 13 144 2.3E-25 T 13-09-2016 THL1_RS09385 21372ded6935ffa60dfbe9434b676005 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 2.9E-15 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS09385 21372ded6935ffa60dfbe9434b676005 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 2.9E-15 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS09385 21372ded6935ffa60dfbe9434b676005 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 2.9E-15 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS09385 21372ded6935ffa60dfbe9434b676005 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 2.9E-15 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS09385 21372ded6935ffa60dfbe9434b676005 144 Gene3D G3DSA:1.10.10.10 4 142 1.9E-34 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09385 21372ded6935ffa60dfbe9434b676005 144 PANTHER PTHR33164 13 144 2.3E-25 T 13-09-2016 THL1_RS09385 21372ded6935ffa60dfbe9434b676005 144 Pfam PF01047 MarR family 33 91 1.8E-11 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS28065 4efef13d712c05950ec66a7747b349fa 403 PANTHER PTHR30572 4 400 9.2E-58 T 13-09-2016 THL1_RS28065 4efef13d712c05950ec66a7747b349fa 403 Pfam PF12704 MacB-like periplasmic core domain 21 240 3.8E-27 T 13-09-2016 IPR025857 MacB-like periplasmic core domain THL1_RS28065 4efef13d712c05950ec66a7747b349fa 403 Pfam PF02687 FtsX-like permease family 281 391 2.0E-19 T 13-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 THL1_RS08655 ae863fd2e6cabeb1fe37f33eac0bed40 199 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 199 32.863 T 13-09-2016 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 THL1_RS08655 ae863fd2e6cabeb1fe37f33eac0bed40 199 PANTHER PTHR10204 1 199 1.1E-93 T 13-09-2016 THL1_RS08655 ae863fd2e6cabeb1fe37f33eac0bed40 199 Gene3D G3DSA:3.40.50.360 1 199 7.8E-70 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS08655 ae863fd2e6cabeb1fe37f33eac0bed40 199 SUPERFAMILY SSF52218 1 197 7.68E-56 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS08655 ae863fd2e6cabeb1fe37f33eac0bed40 199 PANTHER PTHR10204:SF16 1 199 1.1E-93 T 13-09-2016 THL1_RS08655 ae863fd2e6cabeb1fe37f33eac0bed40 199 Pfam PF02525 Flavodoxin-like fold 3 197 1.9E-49 T 13-09-2016 IPR003680 Flavodoxin-like fold THL1_RS03525 272ac1b12c008e14d037c883e4dceeb9 211 SUPERFAMILY SSF50447 1 208 3.0E-80 T 13-09-2016 IPR009000 Translation protein, beta-barrel domain THL1_RS03525 272ac1b12c008e14d037c883e4dceeb9 211 ProSitePatterns PS00474 Ribosomal protein L3 signature. 101 124 - T 13-09-2016 IPR019926 Ribosomal protein L3, conserved site THL1_RS03525 272ac1b12c008e14d037c883e4dceeb9 211 Gene3D G3DSA:4.10.960.10 78 157 9.2E-34 T 13-09-2016 THL1_RS03525 272ac1b12c008e14d037c883e4dceeb9 211 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 204 1.3E-91 T 13-09-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03525 272ac1b12c008e14d037c883e4dceeb9 211 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 207 39.84 T 13-09-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03525 272ac1b12c008e14d037c883e4dceeb9 211 Pfam PF00297 Ribosomal protein L3 44 182 4.9E-16 T 13-09-2016 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03525 272ac1b12c008e14d037c883e4dceeb9 211 Gene3D G3DSA:2.40.30.10 4 33 3.5E-8 T 13-09-2016 THL1_RS03525 272ac1b12c008e14d037c883e4dceeb9 211 Gene3D G3DSA:2.40.30.10 158 207 3.5E-8 T 13-09-2016 THL1_RS03525 272ac1b12c008e14d037c883e4dceeb9 211 PANTHER PTHR11229 1 208 3.9E-117 T 13-09-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS02020 fb9e0906e7c80da1d9cbccee7a296187 149 SUPERFAMILY SSF75516 2 75 1.06E-8 T 13-09-2016 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain THL1_RS02020 fb9e0906e7c80da1d9cbccee7a296187 149 SUPERFAMILY SSF46894 75 149 1.56E-17 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS02020 fb9e0906e7c80da1d9cbccee7a296187 149 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 89 103 9.3E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS02020 fb9e0906e7c80da1d9cbccee7a296187 149 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 103 119 9.3E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS02020 fb9e0906e7c80da1d9cbccee7a296187 149 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 119 131 9.3E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS02020 fb9e0906e7c80da1d9cbccee7a296187 149 Pfam PF00196 Bacterial regulatory proteins, luxR family 88 143 2.5E-17 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS02020 fb9e0906e7c80da1d9cbccee7a296187 149 SMART SM00421 86 143 5.0E-17 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS02020 fb9e0906e7c80da1d9cbccee7a296187 149 Gene3D G3DSA:1.10.10.10 92 149 7.6E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02020 fb9e0906e7c80da1d9cbccee7a296187 149 PANTHER PTHR26402 78 144 3.5E-12 T 13-09-2016 THL1_RS02020 fb9e0906e7c80da1d9cbccee7a296187 149 Gene3D G3DSA:3.30.450.80 1 91 1.2E-9 T 13-09-2016 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain THL1_RS02020 fb9e0906e7c80da1d9cbccee7a296187 149 PANTHER PTHR26402:SF151 78 144 3.5E-12 T 13-09-2016 THL1_RS28160 1af576a2030a749a58d1a6f896da779d 224 PANTHER PTHR13256:SF22 4 212 1.2E-83 T 13-09-2016 THL1_RS28160 1af576a2030a749a58d1a6f896da779d 224 SUPERFAMILY SSF55729 21 189 1.94E-37 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS28160 1af576a2030a749a58d1a6f896da779d 224 PANTHER PTHR13256 4 212 1.2E-83 T 13-09-2016 THL1_RS28160 1af576a2030a749a58d1a6f896da779d 224 Pfam PF13302 Acetyltransferase (GNAT) domain 34 164 2.7E-12 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS28160 1af576a2030a749a58d1a6f896da779d 224 Gene3D G3DSA:3.40.630.30 7 205 5.9E-59 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS14665 bc330e0193a76974b8188f868039f8b4 306 PANTHER PTHR30514:SF3 13 279 3.6E-35 T 13-09-2016 THL1_RS14665 bc330e0193a76974b8188f868039f8b4 306 Gene3D G3DSA:1.10.10.10 15 87 2.2E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14665 bc330e0193a76974b8188f868039f8b4 306 Gene3D G3DSA:3.40.50.10490 114 281 4.7E-27 T 13-09-2016 THL1_RS14665 bc330e0193a76974b8188f868039f8b4 306 Pfam PF01380 SIS domain 140 267 4.1E-19 T 13-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 THL1_RS14665 bc330e0193a76974b8188f868039f8b4 306 PANTHER PTHR30514 13 279 3.6E-35 T 13-09-2016 THL1_RS14665 bc330e0193a76974b8188f868039f8b4 306 SUPERFAMILY SSF53697 111 290 1.85E-29 T 13-09-2016 THL1_RS14665 bc330e0193a76974b8188f868039f8b4 306 Pfam PF01418 Helix-turn-helix domain, rpiR family 17 87 5.6E-15 T 13-09-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 THL1_RS14665 bc330e0193a76974b8188f868039f8b4 306 SUPERFAMILY SSF46689 15 87 3.58E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17095 f35551c791b7340dfacdf6f1659df3fd 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 53 1.8E-7 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS17095 f35551c791b7340dfacdf6f1659df3fd 234 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 61 84 1.8E-7 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS17095 f35551c791b7340dfacdf6f1659df3fd 234 Gene3D G3DSA:1.10.357.10 30 217 5.6E-46 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS17095 f35551c791b7340dfacdf6f1659df3fd 234 Pfam PF13977 Bacterial transcriptional repressor 107 214 5.1E-16 T 13-09-2016 THL1_RS17095 f35551c791b7340dfacdf6f1659df3fd 234 SUPERFAMILY SSF46689 28 101 1.28E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17095 f35551c791b7340dfacdf6f1659df3fd 234 PANTHER PTHR30055 20 226 3.1E-29 T 13-09-2016 THL1_RS17095 f35551c791b7340dfacdf6f1659df3fd 234 Pfam PF00440 Bacterial regulatory proteins, tetR family 40 86 8.4E-14 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS17095 f35551c791b7340dfacdf6f1659df3fd 234 SUPERFAMILY SSF48498 107 214 9.15E-21 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS19525 14d41477bb6e26bd0706f910a3346a11 707 PANTHER PTHR30161:SF1 3 707 0.0 T 13-09-2016 THL1_RS19525 14d41477bb6e26bd0706f910a3346a11 707 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 147 170 - T 13-09-2016 IPR025505 FHIPEP conserved site THL1_RS19525 14d41477bb6e26bd0706f910a3346a11 707 PANTHER PTHR30161 3 707 0.0 T 13-09-2016 THL1_RS19525 14d41477bb6e26bd0706f910a3346a11 707 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 21 704 1.4E-263 T 13-09-2016 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 THL1_RS19525 14d41477bb6e26bd0706f910a3346a11 707 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 242 256 3.3E-55 T 13-09-2016 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 THL1_RS19525 14d41477bb6e26bd0706f910a3346a11 707 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 75 94 3.3E-55 T 13-09-2016 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 THL1_RS19525 14d41477bb6e26bd0706f910a3346a11 707 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 161 179 3.3E-55 T 13-09-2016 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 THL1_RS19525 14d41477bb6e26bd0706f910a3346a11 707 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 191 208 3.3E-55 T 13-09-2016 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 THL1_RS19525 14d41477bb6e26bd0706f910a3346a11 707 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 142 158 3.3E-55 T 13-09-2016 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 THL1_RS19525 14d41477bb6e26bd0706f910a3346a11 707 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 38 51 3.3E-55 T 13-09-2016 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 THL1_RS19525 14d41477bb6e26bd0706f910a3346a11 707 Pfam PF00771 FHIPEP family 32 696 7.4E-269 T 13-09-2016 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 THL1_RS19525 14d41477bb6e26bd0706f910a3346a11 707 PIRSF PIRSF005419 9 707 1.1E-247 T 13-09-2016 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 THL1_RS22075 c16bc4574ec983cfd857e14665621393 224 PIRSF PIRSF006293 2 224 1.7E-80 T 13-09-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 THL1_RS22075 c16bc4574ec983cfd857e14665621393 224 Pfam PF06508 Queuosine biosynthesis protein QueC 5 215 8.0E-80 T 13-09-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 THL1_RS22075 c16bc4574ec983cfd857e14665621393 224 PANTHER PTHR11587 1 223 4.2E-113 T 13-09-2016 THL1_RS22075 c16bc4574ec983cfd857e14665621393 224 SUPERFAMILY SSF52402 4 223 1.61E-65 T 13-09-2016 THL1_RS22075 c16bc4574ec983cfd857e14665621393 224 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 4 221 56.863 T 13-09-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 THL1_RS22075 c16bc4574ec983cfd857e14665621393 224 Gene3D G3DSA:3.40.50.620 3 223 1.7E-81 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS22075 c16bc4574ec983cfd857e14665621393 224 PANTHER PTHR11587:SF3 1 223 4.2E-113 T 13-09-2016 THL1_RS22075 c16bc4574ec983cfd857e14665621393 224 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 6 208 2.0E-62 T 13-09-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 THL1_RS05285 ac8b694ea0afb518d55969e4a374c130 483 PANTHER PTHR11895 1 480 3.0E-229 T 13-09-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS05285 ac8b694ea0afb518d55969e4a374c130 483 SUPERFAMILY SSF75304 2 480 5.89E-172 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS05285 ac8b694ea0afb518d55969e4a374c130 483 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 13 474 2.9E-182 T 13-09-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS05285 ac8b694ea0afb518d55969e4a374c130 483 Gene3D G3DSA:3.90.1300.10 2 480 1.8E-189 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS05285 ac8b694ea0afb518d55969e4a374c130 483 PANTHER PTHR11895:SF7 1 480 3.0E-229 T 13-09-2016 THL1_RS05285 ac8b694ea0afb518d55969e4a374c130 483 Pfam PF01425 Amidase 22 463 3.9E-162 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS05285 ac8b694ea0afb518d55969e4a374c130 483 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 9 474 95.058 T 13-09-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS05285 ac8b694ea0afb518d55969e4a374c130 483 ProSitePatterns PS00571 Amidases signature. 149 180 - T 13-09-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS15650 2ec53222027b4f93cb73301d357c89c3 497 SUPERFAMILY SSF53720 10 496 1.14E-175 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS15650 2ec53222027b4f93cb73301d357c89c3 497 Pfam PF00171 Aldehyde dehydrogenase family 27 493 6.2E-178 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS15650 2ec53222027b4f93cb73301d357c89c3 497 PANTHER PTHR11699 2 497 1.4E-239 T 13-09-2016 THL1_RS15650 2ec53222027b4f93cb73301d357c89c3 497 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 270 277 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS15650 2ec53222027b4f93cb73301d357c89c3 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 298 309 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS15650 2ec53222027b4f93cb73301d357c89c3 497 Gene3D G3DSA:3.40.605.10 18 283 1.4E-104 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS15650 2ec53222027b4f93cb73301d357c89c3 497 Gene3D G3DSA:3.40.309.10 284 468 1.9E-72 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 SUPERFAMILY SSF82693 555 650 6.8E-21 T 13-09-2016 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 PANTHER PTHR32063 1 1007 0.0 T 13-09-2016 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 SUPERFAMILY SSF82714 183 264 4.97E-16 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 SUPERFAMILY SSF82693 40 134 2.62E-26 T 13-09-2016 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 Pfam PF00873 AcrB/AcrD/AcrF family 4 1004 0.0 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 Gene3D G3DSA:3.30.70.1430 40 140 1.5E-29 T 13-09-2016 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 Gene3D G3DSA:3.30.2090.10 701 786 4.9E-17 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 Gene3D G3DSA:3.30.2090.10 183 265 3.4E-21 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 SUPERFAMILY SSF82693 267 323 4.92E-24 T 13-09-2016 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 SUPERFAMILY SSF82693 135 181 4.92E-24 T 13-09-2016 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 Gene3D G3DSA:1.10.3850.10 793 1007 5.8E-64 T 13-09-2016 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 Gene3D G3DSA:1.10.3850.10 271 491 1.3E-60 T 13-09-2016 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 Gene3D G3DSA:3.30.70.1430 557 650 2.3E-14 T 13-09-2016 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 SUPERFAMILY SSF82866 291 489 8.89E-50 T 13-09-2016 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 9.3E-82 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 9.3E-82 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 PRINTS PR00702 Acriflavin resistance protein family signature 605 619 9.3E-82 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 9.3E-82 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 9.3E-82 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 9.3E-82 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 PRINTS PR00702 Acriflavin resistance protein family signature 542 559 9.3E-82 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 9.3E-82 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 9.3E-82 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 SUPERFAMILY SSF82714 701 786 2.49E-15 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 PANTHER PTHR32063:SF14 1 1007 0.0 T 13-09-2016 THL1_RS16000 1366542e0f05cae4fef85ff9f8127adf 1019 SUPERFAMILY SSF82866 786 1009 7.59E-50 T 13-09-2016 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 Pfam PF07695 7TM diverse intracellular signalling 192 392 2.0E-36 T 13-09-2016 IPR011623 7TM-DISM receptor, extracellular domain, type 1 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 PANTHER PTHR24423 408 647 6.3E-167 T 13-09-2016 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 SMART SM00387 528 644 2.0E-39 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 528 643 5.3E-28 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 SMART SM00448 796 914 8.3E-35 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 SMART SM00388 416 481 2.8E-23 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 PANTHER PTHR24423:SF548 86 112 6.3E-167 T 13-09-2016 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 PANTHER PTHR24423:SF548 680 924 6.3E-167 T 13-09-2016 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 PANTHER PTHR24423 86 112 6.3E-167 T 13-09-2016 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 SUPERFAMILY SSF52172 796 918 1.71E-34 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 Pfam PF00072 Response regulator receiver domain 798 913 8.7E-24 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 PANTHER PTHR24423 680 924 6.3E-167 T 13-09-2016 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 Pfam PF00512 His Kinase A (phospho-acceptor) domain 416 481 1.4E-19 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 SUPERFAMILY SSF55874 470 644 5.89E-48 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 Gene3D G3DSA:1.10.287.130 408 466 4.0E-16 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 Pfam PF07696 7TMR-DISM extracellular 2 45 176 1.1E-32 T 13-09-2016 IPR011622 7TM-DISM receptor, extracellular domain, type 2 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 PANTHER PTHR24423:SF548 408 647 6.3E-167 T 13-09-2016 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 PRINTS PR00344 Bacterial sensor protein C-terminal signature 628 641 2.8E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 PRINTS PR00344 Bacterial sensor protein C-terminal signature 587 597 2.8E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 PRINTS PR00344 Bacterial sensor protein C-terminal signature 569 583 2.8E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 PRINTS PR00344 Bacterial sensor protein C-terminal signature 604 622 2.8E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 SUPERFAMILY SSF47384 404 482 1.08E-20 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 Gene3D G3DSA:3.30.565.10 467 644 7.0E-48 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS06890 01a6dc384b6ada98435cf7f4ca12f9f3 925 Gene3D G3DSA:3.40.50.2300 785 920 7.2E-37 T 13-09-2016 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Gene3D G3DSA:1.10.287.560 1938 1972 8.0E-5 T 13-09-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Gene3D G3DSA:1.10.287.560 2052 2077 8.0E-5 T 13-09-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Gene3D G3DSA:1.20.120.160 900 1036 9.4E-29 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Gene3D G3DSA:1.20.120.160 1057 1188 1.9E-21 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Gene3D G3DSA:1.20.120.160 1619 1752 9.7E-31 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Gene3D G3DSA:1.20.120.160 1771 1889 6.5E-22 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Gene3D G3DSA:1.20.120.160 10 142 1.5E-15 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Gene3D G3DSA:1.20.120.160 1398 1533 4.7E-28 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Pfam PF01627 Hpt domain 10 98 2.3E-6 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Pfam PF01627 Hpt domain 1624 1724 8.8E-15 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Pfam PF01627 Hpt domain 901 990 6.3E-11 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Pfam PF01627 Hpt domain 1401 1501 7.6E-14 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Pfam PF01627 Hpt domain 1772 1872 1.4E-13 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Pfam PF01627 Hpt domain 1059 1151 1.9E-12 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SUPERFAMILY SSF47226 1399 1520 2.62E-25 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SMART SM00073 898 1003 2.0E-5 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SMART SM00073 1057 1160 0.017 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SMART SM00073 1770 1871 3.6E-5 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SMART SM00073 1622 1719 3.1E-4 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SMART SM00073 1399 1496 1.9E-6 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Gene3D G3DSA:3.30.565.10 2078 2260 6.9E-34 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SUPERFAMILY SSF47226 433 557 2.83E-14 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 2125 2261 7.1E-15 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SMART SM00387 2121 2262 3.5E-26 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 PANTHER PTHR22617:SF28 1600 1986 0.0 T 13-09-2016 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SUPERFAMILY SSF47226 900 1023 3.06E-25 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SUPERFAMILY SSF47226 1198 1320 5.36E-15 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Gene3D G3DSA:2.30.30.40 2353 2395 5.2E-21 T 13-09-2016 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Gene3D G3DSA:2.30.30.40 2262 2283 5.2E-21 T 13-09-2016 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SUPERFAMILY SSF50341 2261 2394 2.49E-23 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Pfam PF01584 CheW-like domain 2267 2400 7.3E-23 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SUPERFAMILY SSF47226 1772 1876 2.88E-19 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 2222 2240 1.6E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 2166 2180 1.6E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 PRINTS PR00344 Bacterial sensor protein C-terminal signature 2246 2259 1.6E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SMART SM00260 2254 2398 1.8E-32 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SUPERFAMILY SSF47226 1057 1179 1.02E-19 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SUPERFAMILY SSF47226 1622 1743 6.02E-26 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 PANTHER PTHR22617 1600 1986 0.0 T 13-09-2016 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SMART SM00448 2428 2541 6.0E-37 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Gene3D G3DSA:1.20.120.160 1198 1298 1.8E-15 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 PANTHER PTHR22617:SF28 2054 2414 0.0 T 13-09-2016 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SMART SM01231 1937 2076 7.1E-11 T 13-09-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SUPERFAMILY SSF52172 2427 2546 1.42E-37 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Pfam PF00072 Response regulator receiver domain 2430 2541 1.9E-27 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SUPERFAMILY SSF55874 2078 2259 4.98E-37 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 SUPERFAMILY SSF47226 7 130 5.1E-21 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 PANTHER PTHR22617 2054 2414 0.0 T 13-09-2016 THL1_RS01545 1f17539751f740b204f223cbd2f4125c 2548 Gene3D G3DSA:3.40.50.2300 2428 2547 8.9E-39 T 13-09-2016 THL1_RS03065 be0a0cf8fecdf9d37ee241eab910358a 292 Pfam PF00483 Nucleotidyl transferase 2 238 6.1E-72 T 13-09-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 THL1_RS03065 be0a0cf8fecdf9d37ee241eab910358a 292 PANTHER PTHR22572:SF105 2 268 6.9E-178 T 13-09-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 THL1_RS03065 be0a0cf8fecdf9d37ee241eab910358a 292 Gene3D G3DSA:3.90.550.10 1 259 1.3E-68 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS03065 be0a0cf8fecdf9d37ee241eab910358a 292 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 5.0E-157 T 13-09-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 THL1_RS03065 be0a0cf8fecdf9d37ee241eab910358a 292 PANTHER PTHR22572 2 268 6.9E-178 T 13-09-2016 THL1_RS03065 be0a0cf8fecdf9d37ee241eab910358a 292 SUPERFAMILY SSF53448 1 286 6.53E-95 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS12165 e7ee1da70caa7c59c82b7b025aa1cd9b 373 PANTHER PTHR10160 1 371 2.7E-194 T 13-09-2016 THL1_RS12165 e7ee1da70caa7c59c82b7b025aa1cd9b 373 Gene3D G3DSA:3.40.50.720 176 199 4.4E-4 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS12165 e7ee1da70caa7c59c82b7b025aa1cd9b 373 Gene3D G3DSA:3.40.50.1770 1 175 6.9E-60 T 13-09-2016 THL1_RS12165 e7ee1da70caa7c59c82b7b025aa1cd9b 373 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 1.7E-152 T 13-09-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 THL1_RS12165 e7ee1da70caa7c59c82b7b025aa1cd9b 373 SMART SM01002 149 297 3.8E-86 T 13-09-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain THL1_RS12165 e7ee1da70caa7c59c82b7b025aa1cd9b 373 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 1.1E-46 T 13-09-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal THL1_RS12165 e7ee1da70caa7c59c82b7b025aa1cd9b 373 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 6.7E-80 T 13-09-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain THL1_RS12165 e7ee1da70caa7c59c82b7b025aa1cd9b 373 Gene3D G3DSA:3.40.50.1770 200 354 4.5E-29 T 13-09-2016 THL1_RS12165 e7ee1da70caa7c59c82b7b025aa1cd9b 373 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 13-09-2016 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 THL1_RS12165 e7ee1da70caa7c59c82b7b025aa1cd9b 373 PIRSF PIRSF000183 1 371 2.6E-151 T 13-09-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 THL1_RS12165 e7ee1da70caa7c59c82b7b025aa1cd9b 373 SMART SM01003 4 137 3.3E-75 T 13-09-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal THL1_RS12165 e7ee1da70caa7c59c82b7b025aa1cd9b 373 SUPERFAMILY SSF52283 305 359 3.66E-63 T 13-09-2016 THL1_RS12165 e7ee1da70caa7c59c82b7b025aa1cd9b 373 SUPERFAMILY SSF52283 1 137 3.66E-63 T 13-09-2016 THL1_RS12165 e7ee1da70caa7c59c82b7b025aa1cd9b 373 SUPERFAMILY SSF51735 137 303 2.63E-46 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS17765 1999ceb5db93c947260145f89af9428f 72 Pfam PF11174 Protein of unknown function (DUF2970) 12 67 8.7E-25 T 13-09-2016 IPR021344 Protein of unknown function DUF2970 THL1_RS17075 66f5a0eee5145979e77df3f7d973cede 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.4E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS17075 66f5a0eee5145979e77df3f7d973cede 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.4E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS17075 66f5a0eee5145979e77df3f7d973cede 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.4E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS17075 66f5a0eee5145979e77df3f7d973cede 308 SUPERFAMILY SSF53850 91 291 8.22E-33 T 13-09-2016 THL1_RS17075 66f5a0eee5145979e77df3f7d973cede 308 Pfam PF03466 LysR substrate binding domain 87 290 6.6E-34 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS17075 66f5a0eee5145979e77df3f7d973cede 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.3E-21 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS17075 66f5a0eee5145979e77df3f7d973cede 308 Gene3D G3DSA:3.40.190.10 90 174 2.6E-17 T 13-09-2016 THL1_RS17075 66f5a0eee5145979e77df3f7d973cede 308 Gene3D G3DSA:1.10.10.10 2 85 7.6E-29 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS17075 66f5a0eee5145979e77df3f7d973cede 308 PANTHER PTHR30346:SF6 1 307 2.1E-76 T 13-09-2016 THL1_RS17075 66f5a0eee5145979e77df3f7d973cede 308 Gene3D G3DSA:3.40.190.10 175 262 1.6E-16 T 13-09-2016 THL1_RS17075 66f5a0eee5145979e77df3f7d973cede 308 SUPERFAMILY SSF46785 2 84 1.36E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS17075 66f5a0eee5145979e77df3f7d973cede 308 PANTHER PTHR30346 1 307 2.1E-76 T 13-09-2016 THL1_RS14025 5909088ae60d61c118b03483349c48ff 281 SUPERFAMILY SSF161098 8 257 1.96E-48 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS14025 5909088ae60d61c118b03483349c48ff 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 268 9.3E-19 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS14025 5909088ae60d61c118b03483349c48ff 281 Gene3D G3DSA:1.10.3720.10 11 268 1.6E-44 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS14025 5909088ae60d61c118b03483349c48ff 281 PANTHER PTHR30193:SF20 1 276 2.8E-54 T 13-09-2016 THL1_RS14025 5909088ae60d61c118b03483349c48ff 281 PANTHER PTHR30193 1 276 2.8E-54 T 13-09-2016 THL1_RS19130 51979bd84affd5b808a1934acf8899e2 295 Gene3D G3DSA:3.40.190.10 97 177 3.6E-5 T 13-09-2016 THL1_RS19130 51979bd84affd5b808a1934acf8899e2 295 Gene3D G3DSA:1.10.10.10 9 90 2.4E-26 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19130 51979bd84affd5b808a1934acf8899e2 295 Pfam PF03466 LysR substrate binding domain 94 292 2.3E-26 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS19130 51979bd84affd5b808a1934acf8899e2 295 PANTHER PTHR30537 2 295 4.1E-69 T 13-09-2016 THL1_RS19130 51979bd84affd5b808a1934acf8899e2 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 2.1E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19130 51979bd84affd5b808a1934acf8899e2 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 2.1E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19130 51979bd84affd5b808a1934acf8899e2 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 2.1E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19130 51979bd84affd5b808a1934acf8899e2 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 69 3.1E-20 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19130 51979bd84affd5b808a1934acf8899e2 295 SUPERFAMILY SSF53850 93 293 3.62E-26 T 13-09-2016 THL1_RS19130 51979bd84affd5b808a1934acf8899e2 295 SUPERFAMILY SSF46785 9 93 8.3E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19130 51979bd84affd5b808a1934acf8899e2 295 PANTHER PTHR30537:SF26 2 295 4.1E-69 T 13-09-2016 THL1_RS19130 51979bd84affd5b808a1934acf8899e2 295 Gene3D G3DSA:3.40.190.10 178 263 1.0E-21 T 13-09-2016 THL1_RS18780 e956831277577f71bd28663abc2de869 459 PANTHER PTHR11102 32 150 2.9E-17 T 13-09-2016 THL1_RS18780 e956831277577f71bd28663abc2de869 459 PANTHER PTHR11102 295 398 2.9E-17 T 13-09-2016 THL1_RS18780 e956831277577f71bd28663abc2de869 459 Pfam PF08238 Sel1 repeat 301 332 0.0016 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS18780 e956831277577f71bd28663abc2de869 459 Pfam PF08238 Sel1 repeat 52 82 75.0 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS18780 e956831277577f71bd28663abc2de869 459 Pfam PF08238 Sel1 repeat 335 370 0.34 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS18780 e956831277577f71bd28663abc2de869 459 SMART SM00671 371 406 16.0 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS18780 e956831277577f71bd28663abc2de869 459 SMART SM00671 300 334 1.2 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS18780 e956831277577f71bd28663abc2de869 459 SMART SM00671 51 85 22.0 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS18780 e956831277577f71bd28663abc2de869 459 SMART SM00671 335 370 0.0024 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS18780 e956831277577f71bd28663abc2de869 459 SUPERFAMILY SSF81901 252 414 9.59E-17 T 13-09-2016 THL1_RS18780 e956831277577f71bd28663abc2de869 459 Gene3D G3DSA:1.25.40.10 24 137 1.9E-29 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS18780 e956831277577f71bd28663abc2de869 459 Gene3D G3DSA:1.25.40.10 284 421 1.9E-29 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS18780 e956831277577f71bd28663abc2de869 459 SUPERFAMILY SSF81901 24 134 1.57E-6 T 13-09-2016 THL1_RS03860 bec660a8260b2f7f12095481916a3e01 158 Gene3D G3DSA:3.40.50.960 5 156 1.1E-63 T 13-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS03860 bec660a8260b2f7f12095481916a3e01 158 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 16 151 5.0E-53 T 13-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS03860 bec660a8260b2f7f12095481916a3e01 158 SUPERFAMILY SSF52121 5 155 8.77E-61 T 13-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS03860 bec660a8260b2f7f12095481916a3e01 158 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 10 155 30.996 T 13-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS03860 bec660a8260b2f7f12095481916a3e01 158 PANTHER PTHR21058 1 157 7.4E-75 T 13-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS03860 bec660a8260b2f7f12095481916a3e01 158 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 16 152 7.4E-55 T 13-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS04805 90889929475655157bfcc457d443fb94 205 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 117 202 6.9E-26 T 13-09-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 THL1_RS04805 90889929475655157bfcc457d443fb94 205 PANTHER PTHR10516 86 204 1.3E-85 T 13-09-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type THL1_RS04805 90889929475655157bfcc457d443fb94 205 PANTHER PTHR10516:SF320 6 67 1.3E-85 T 13-09-2016 THL1_RS04805 90889929475655157bfcc457d443fb94 205 PANTHER PTHR10516 6 67 1.3E-85 T 13-09-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type THL1_RS04805 90889929475655157bfcc457d443fb94 205 Gene3D G3DSA:1.10.287.460 3 92 3.0E-20 T 13-09-2016 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 THL1_RS04805 90889929475655157bfcc457d443fb94 205 Gene3D G3DSA:3.10.50.40 93 204 1.4E-42 T 13-09-2016 THL1_RS04805 90889929475655157bfcc457d443fb94 205 SUPERFAMILY SSF54534 7 204 4.85E-55 T 13-09-2016 THL1_RS04805 90889929475655157bfcc457d443fb94 205 PANTHER PTHR10516:SF320 86 204 1.3E-85 T 13-09-2016 THL1_RS04805 90889929475655157bfcc457d443fb94 205 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 5 108 1.4E-21 T 13-09-2016 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 THL1_RS23105 f3ce5f8b3f812b22a45c7bedd062b998 257 PANTHER PTHR30383 45 254 2.8E-13 T 13-09-2016 THL1_RS23105 f3ce5f8b3f812b22a45c7bedd062b998 257 Gene3D G3DSA:3.40.50.1110 53 238 1.4E-19 T 13-09-2016 IPR013830 SGNH hydrolase-type esterase domain THL1_RS23105 f3ce5f8b3f812b22a45c7bedd062b998 257 PANTHER PTHR30383:SF5 45 254 2.8E-13 T 13-09-2016 THL1_RS23105 f3ce5f8b3f812b22a45c7bedd062b998 257 SUPERFAMILY SSF52266 51 238 5.36E-27 T 13-09-2016 IPR013830 SGNH hydrolase-type esterase domain THL1_RS23105 f3ce5f8b3f812b22a45c7bedd062b998 257 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 59 229 2.9E-13 T 13-09-2016 IPR013830 SGNH hydrolase-type esterase domain THL1_RS26065 96e605a114c6840e351ba62f8246d967 425 PANTHER PTHR10909 1 421 3.7E-188 T 13-09-2016 THL1_RS26065 96e605a114c6840e351ba62f8246d967 425 Gene3D G3DSA:2.40.110.10 188 277 1.9E-19 T 13-09-2016 THL1_RS26065 96e605a114c6840e351ba62f8246d967 425 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 69 180 2.0E-18 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS26065 96e605a114c6840e351ba62f8246d967 425 PANTHER PTHR10909:SF243 1 421 3.7E-188 T 13-09-2016 THL1_RS26065 96e605a114c6840e351ba62f8246d967 425 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 393 412 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS26065 96e605a114c6840e351ba62f8246d967 425 SUPERFAMILY SSF56645 64 285 1.96E-42 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS26065 96e605a114c6840e351ba62f8246d967 425 Gene3D G3DSA:1.20.140.10 278 421 3.1E-39 T 13-09-2016 THL1_RS26065 96e605a114c6840e351ba62f8246d967 425 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 188 277 2.0E-11 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS26065 96e605a114c6840e351ba62f8246d967 425 Gene3D G3DSA:1.10.540.10 63 179 3.1E-23 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS26065 96e605a114c6840e351ba62f8246d967 425 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 294 421 2.6E-29 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS26065 96e605a114c6840e351ba62f8246d967 425 SUPERFAMILY SSF47203 292 421 2.09E-38 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS26230 4e5b80f8729f6452ca66ec1f7f05d533 1105 Pfam PF00924 Mechanosensitive ion channel 867 1066 1.6E-51 T 13-09-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 THL1_RS26230 4e5b80f8729f6452ca66ec1f7f05d533 1105 Pfam PF12794 Mechanosensitive ion channel inner membrane domain 1 486 806 3.6E-103 T 13-09-2016 IPR025692 Mechanosensitive ion channel inner membrane domain 1 THL1_RS26230 4e5b80f8729f6452ca66ec1f7f05d533 1105 Gene3D G3DSA:2.30.30.60 925 974 1.9E-16 T 13-09-2016 THL1_RS26230 4e5b80f8729f6452ca66ec1f7f05d533 1105 SUPERFAMILY SSF82689 978 1067 1.7E-15 T 13-09-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 THL1_RS26230 4e5b80f8729f6452ca66ec1f7f05d533 1105 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 939 973 - T 13-09-2016 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 THL1_RS26230 4e5b80f8729f6452ca66ec1f7f05d533 1105 Gene3D G3DSA:3.30.70.100 980 1064 2.1E-14 T 13-09-2016 THL1_RS26230 4e5b80f8729f6452ca66ec1f7f05d533 1105 SUPERFAMILY SSF82861 823 908 1.19E-7 T 13-09-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 THL1_RS26230 4e5b80f8729f6452ca66ec1f7f05d533 1105 PANTHER PTHR30347:SF2 53 1103 0.0 T 13-09-2016 THL1_RS26230 4e5b80f8729f6452ca66ec1f7f05d533 1105 SUPERFAMILY SSF50182 910 975 4.25E-16 T 13-09-2016 IPR010920 LSM domain THL1_RS26230 4e5b80f8729f6452ca66ec1f7f05d533 1105 Pfam PF12795 Mechanosensitive ion channel porin domain 53 266 8.5E-50 T 13-09-2016 IPR024393 Mechanosensitive ion channel MscS, porin domain THL1_RS26230 4e5b80f8729f6452ca66ec1f7f05d533 1105 PANTHER PTHR30347 53 1103 0.0 T 13-09-2016 THL1_RS06730 bb4e7b5075e4a9f4883f0d17e2e5f620 329 PANTHER PTHR24220:SF150 5 281 1.2E-119 T 13-09-2016 THL1_RS06730 bb4e7b5075e4a9f4883f0d17e2e5f620 329 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS06730 bb4e7b5075e4a9f4883f0d17e2e5f620 329 PANTHER PTHR24220 5 281 1.2E-119 T 13-09-2016 THL1_RS06730 bb4e7b5075e4a9f4883f0d17e2e5f620 329 Gene3D G3DSA:3.40.50.300 4 236 6.0E-82 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06730 bb4e7b5075e4a9f4883f0d17e2e5f620 329 Pfam PF00005 ABC transporter 20 161 3.3E-35 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS06730 bb4e7b5075e4a9f4883f0d17e2e5f620 329 SUPERFAMILY SSF52540 4 241 1.46E-85 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06730 bb4e7b5075e4a9f4883f0d17e2e5f620 329 SUPERFAMILY SSF50331 256 325 7.37E-9 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS06730 bb4e7b5075e4a9f4883f0d17e2e5f620 329 SMART SM00382 28 211 1.7E-17 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS06730 bb4e7b5075e4a9f4883f0d17e2e5f620 329 Pfam PF08402 TOBE domain 257 325 3.3E-9 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS01705 fe8e2eb92c1827bcc663eacafd2c4c38 247 PANTHER PTHR35936 6 247 1.1E-43 T 13-09-2016 THL1_RS01705 fe8e2eb92c1827bcc663eacafd2c4c38 247 SUPERFAMILY SSF53850 21 242 2.57E-45 T 13-09-2016 THL1_RS01705 fe8e2eb92c1827bcc663eacafd2c4c38 247 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 41 242 4.0E-26 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS01705 fe8e2eb92c1827bcc663eacafd2c4c38 247 Gene3D G3DSA:3.40.190.10 98 186 1.6E-5 T 13-09-2016 THL1_RS01705 fe8e2eb92c1827bcc663eacafd2c4c38 247 PANTHER PTHR35936:SF3 6 247 1.1E-43 T 13-09-2016 THL1_RS01705 fe8e2eb92c1827bcc663eacafd2c4c38 247 Gene3D G3DSA:3.40.190.10 21 97 3.7E-18 T 13-09-2016 THL1_RS01705 fe8e2eb92c1827bcc663eacafd2c4c38 247 Gene3D G3DSA:3.40.190.10 202 243 3.7E-18 T 13-09-2016 THL1_RS01705 fe8e2eb92c1827bcc663eacafd2c4c38 247 SMART SM00062 23 246 3.5E-15 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS12220 3f756b0b25ae514ee82c781673ce28ec 560 Pfam PF17200 Single Cache domain 2 49 195 9.6E-22 T 13-09-2016 IPR033480 Single Cache domain 2 THL1_RS12220 3f756b0b25ae514ee82c781673ce28ec 560 SMART SM00283 298 559 1.2E-77 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS12220 3f756b0b25ae514ee82c781673ce28ec 560 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 374 558 1.9E-44 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS12220 3f756b0b25ae514ee82c781673ce28ec 560 PANTHER PTHR32089 90 560 4.4E-157 T 13-09-2016 THL1_RS12220 3f756b0b25ae514ee82c781673ce28ec 560 Gene3D G3DSA:1.10.287.950 313 528 8.0E-57 T 13-09-2016 THL1_RS12220 3f756b0b25ae514ee82c781673ce28ec 560 Pfam PF00672 HAMP domain 210 279 2.8E-13 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS12220 3f756b0b25ae514ee82c781673ce28ec 560 Gene3D G3DSA:3.30.450.20 39 187 7.6E-30 T 13-09-2016 THL1_RS12220 3f756b0b25ae514ee82c781673ce28ec 560 PANTHER PTHR32089:SF34 90 560 4.4E-157 T 13-09-2016 THL1_RS12220 3f756b0b25ae514ee82c781673ce28ec 560 SMART SM00304 229 283 2.1E-12 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS12220 3f756b0b25ae514ee82c781673ce28ec 560 SMART SM01049 44 135 2.7E-22 T 13-09-2016 IPR033480 Single Cache domain 2 THL1_RS12220 3f756b0b25ae514ee82c781673ce28ec 560 SUPERFAMILY SSF58104 251 560 8.89E-77 T 13-09-2016 THL1_RS12220 3f756b0b25ae514ee82c781673ce28ec 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 12 37 2.3E-23 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS12220 3f756b0b25ae514ee82c781673ce28ec 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 319 348 2.3E-23 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS12220 3f756b0b25ae514ee82c781673ce28ec 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 425 454 2.3E-23 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS12220 3f756b0b25ae514ee82c781673ce28ec 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 396 423 2.3E-23 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS01240 d79da37b63b0c72dfbafb6975bc0415b 238 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 52 237 4.9E-59 T 13-09-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 THL1_RS01240 d79da37b63b0c72dfbafb6975bc0415b 238 PANTHER PTHR23417 11 236 1.1E-75 T 13-09-2016 THL1_RS01240 d79da37b63b0c72dfbafb6975bc0415b 238 SUPERFAMILY SSF53335 14 237 6.42E-41 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS01240 d79da37b63b0c72dfbafb6975bc0415b 238 PANTHER PTHR23417:SF14 11 236 1.1E-75 T 13-09-2016 THL1_RS01240 d79da37b63b0c72dfbafb6975bc0415b 238 Pfam PF02390 Putative methyltransferase 63 232 1.5E-55 T 13-09-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 THL1_RS01240 d79da37b63b0c72dfbafb6975bc0415b 238 Gene3D G3DSA:3.40.50.150 59 221 2.0E-14 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS01240 d79da37b63b0c72dfbafb6975bc0415b 238 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 23 237 29.641 T 13-09-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 THL1_RS01755 5e979fe1c141a5e7732c77e66ff2d7b1 398 PANTHER PTHR24220 42 272 5.8E-143 T 13-09-2016 THL1_RS01755 5e979fe1c141a5e7732c77e66ff2d7b1 398 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 39 396 1.6E-123 T 13-09-2016 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 THL1_RS01755 5e979fe1c141a5e7732c77e66ff2d7b1 398 Gene3D G3DSA:3.10.580.10 299 395 9.1E-11 T 13-09-2016 THL1_RS01755 5e979fe1c141a5e7732c77e66ff2d7b1 398 Pfam PF00005 ABC transporter 46 193 2.4E-32 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS01755 5e979fe1c141a5e7732c77e66ff2d7b1 398 PANTHER PTHR24220 7 17 5.8E-143 T 13-09-2016 THL1_RS01755 5e979fe1c141a5e7732c77e66ff2d7b1 398 SUPERFAMILY SSF54631 299 397 8.61E-9 T 13-09-2016 THL1_RS01755 5e979fe1c141a5e7732c77e66ff2d7b1 398 PANTHER PTHR24220:SF374 7 17 5.8E-143 T 13-09-2016 THL1_RS01755 5e979fe1c141a5e7732c77e66ff2d7b1 398 SMART SM00382 54 244 1.3E-16 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS01755 5e979fe1c141a5e7732c77e66ff2d7b1 398 SUPERFAMILY SSF52540 44 271 1.93E-76 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01755 5e979fe1c141a5e7732c77e66ff2d7b1 398 Gene3D G3DSA:3.40.50.300 39 266 2.1E-78 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01755 5e979fe1c141a5e7732c77e66ff2d7b1 398 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS01755 5e979fe1c141a5e7732c77e66ff2d7b1 398 PANTHER PTHR24220:SF374 42 272 5.8E-143 T 13-09-2016 THL1_RS20625 9f665541d31030df664ce020a0752d63 107 SUPERFAMILY SSF54292 3 104 1.52E-33 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS20625 9f665541d31030df664ce020a0752d63 107 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 40 50 - T 13-09-2016 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 THL1_RS20625 9f665541d31030df664ce020a0752d63 107 PRINTS PR00355 Adrenodoxin signature 59 73 8.5E-7 T 13-09-2016 IPR001055 Adrenodoxin GO:0009055|GO:0051537 THL1_RS20625 9f665541d31030df664ce020a0752d63 107 PRINTS PR00355 Adrenodoxin signature 40 50 8.5E-7 T 13-09-2016 IPR001055 Adrenodoxin GO:0009055|GO:0051537 THL1_RS20625 9f665541d31030df664ce020a0752d63 107 PRINTS PR00355 Adrenodoxin signature 83 91 8.5E-7 T 13-09-2016 IPR001055 Adrenodoxin GO:0009055|GO:0051537 THL1_RS20625 9f665541d31030df664ce020a0752d63 107 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 92 6.3E-16 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS20625 9f665541d31030df664ce020a0752d63 107 PANTHER PTHR23426 3 104 8.6E-25 T 13-09-2016 THL1_RS20625 9f665541d31030df664ce020a0752d63 107 Gene3D G3DSA:3.10.20.30 3 105 1.0E-34 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS10930 e1eaa2f367157177575c193b04e1eb5a 147 PANTHER PTHR12418:SF18 1 142 4.8E-59 T 13-09-2016 THL1_RS10930 e1eaa2f367157177575c193b04e1eb5a 147 Gene3D G3DSA:3.10.129.10 20 144 2.4E-19 T 13-09-2016 IPR029069 HotDog domain THL1_RS10930 e1eaa2f367157177575c193b04e1eb5a 147 Pfam PF03061 Thioesterase superfamily 61 133 2.2E-13 T 13-09-2016 IPR006683 Thioesterase domain THL1_RS10930 e1eaa2f367157177575c193b04e1eb5a 147 PANTHER PTHR12418 1 142 4.8E-59 T 13-09-2016 THL1_RS10930 e1eaa2f367157177575c193b04e1eb5a 147 SUPERFAMILY SSF54637 20 144 2.26E-22 T 13-09-2016 IPR029069 HotDog domain THL1_RS22520 9a4f83e6d8fd7b49f93cc6d98799a828 370 SUPERFAMILY SSF51735 161 334 1.81E-47 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS22520 9a4f83e6d8fd7b49f93cc6d98799a828 370 SUPERFAMILY SSF50129 319 370 5.65E-11 T 13-09-2016 IPR011032 GroES-like THL1_RS22520 9a4f83e6d8fd7b49f93cc6d98799a828 370 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 13-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 THL1_RS22520 9a4f83e6d8fd7b49f93cc6d98799a828 370 SMART SM00829 11 368 4.9E-4 T 13-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THL1_RS22520 9a4f83e6d8fd7b49f93cc6d98799a828 370 SUPERFAMILY SSF50129 2 185 2.95E-73 T 13-09-2016 IPR011032 GroES-like THL1_RS22520 9a4f83e6d8fd7b49f93cc6d98799a828 370 Gene3D G3DSA:3.40.50.720 191 310 9.7E-44 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS22520 9a4f83e6d8fd7b49f93cc6d98799a828 370 PANTHER PTHR11695:SF560 129 370 2.8E-217 T 13-09-2016 THL1_RS22520 9a4f83e6d8fd7b49f93cc6d98799a828 370 PANTHER PTHR11695 16 109 2.8E-217 T 13-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 THL1_RS22520 9a4f83e6d8fd7b49f93cc6d98799a828 370 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 155 3.0E-26 T 13-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THL1_RS22520 9a4f83e6d8fd7b49f93cc6d98799a828 370 Gene3D G3DSA:3.90.180.10 2 190 5.3E-71 T 13-09-2016 IPR011032 GroES-like THL1_RS22520 9a4f83e6d8fd7b49f93cc6d98799a828 370 PANTHER PTHR11695:SF560 16 109 2.8E-217 T 13-09-2016 THL1_RS22520 9a4f83e6d8fd7b49f93cc6d98799a828 370 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 3 370 1.0E-225 T 13-09-2016 IPR014183 Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00040+1.1.1.-|KEGG: 00051+1.1.1.-|KEGG: 00071+1.1.1.1|KEGG: 00140+1.1.1.-|KEGG: 00240+1.1.1.-|KEGG: 00253+1.1.1.-|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00362+1.1.1.-|KEGG: 00363+1.1.1.-|KEGG: 00365+1.1.1.-|KEGG: 00400+1.1.1.-|KEGG: 00520+1.1.1.-|KEGG: 00523+1.1.1.-|KEGG: 00591+1.1.1.-|KEGG: 00592+1.1.1.1|KEGG: 00620+1.1.1.28|KEGG: 00622+1.1.1.-|KEGG: 00625+1.1.1.1+1.1.1.-|KEGG: 00626+1.1.1.1|KEGG: 00633+1.1.1.-|KEGG: 00640+1.1.1.-|KEGG: 00650+1.1.1.-|KEGG: 00680+1.1.1.284+1.1.1.-|KEGG: 00720+1.1.1.-|KEGG: 00750+1.1.1.-|KEGG: 00830+1.1.1.1+1.1.1.-|KEGG: 00950+1.1.1.-|KEGG: 00966+1.1.1.-|KEGG: 00980+1.1.1.1|KEGG: 00981+1.1.1.-|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6454|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-6901|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 THL1_RS22520 9a4f83e6d8fd7b49f93cc6d98799a828 370 PANTHER PTHR11695 129 370 2.8E-217 T 13-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 THL1_RS22520 9a4f83e6d8fd7b49f93cc6d98799a828 370 Pfam PF00107 Zinc-binding dehydrogenase 198 327 4.8E-25 T 13-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THL1_RS05970 feb274c499a01c7663a8a1a9650436d8 382 PIRSF PIRSF006004 4 367 3.3E-150 T 13-09-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS05970 feb274c499a01c7663a8a1a9650436d8 382 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 7 354 72.275 T 13-09-2016 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS05970 feb274c499a01c7663a8a1a9650436d8 382 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 5 358 1.2E-140 T 13-09-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS05970 feb274c499a01c7663a8a1a9650436d8 382 Pfam PF04055 Radical SAM superfamily 111 279 3.1E-15 T 13-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 THL1_RS05970 feb274c499a01c7663a8a1a9650436d8 382 PANTHER PTHR30544 1 361 4.2E-181 T 13-09-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS05970 feb274c499a01c7663a8a1a9650436d8 382 Gene3D G3DSA:3.20.20.70 107 335 6.1E-14 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS05970 feb274c499a01c7663a8a1a9650436d8 382 PANTHER PTHR30544:SF5 1 361 4.2E-181 T 13-09-2016 THL1_RS05970 feb274c499a01c7663a8a1a9650436d8 382 SUPERFAMILY SSF102114 107 321 9.03E-14 T 13-09-2016 THL1_RS07420 5fb9ed15d9cb947df21348dcaf8541e1 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 29 87 1.0E-13 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS07420 5fb9ed15d9cb947df21348dcaf8541e1 321 SUPERFAMILY SSF46785 27 110 8.71E-15 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07420 5fb9ed15d9cb947df21348dcaf8541e1 321 PANTHER PTHR30126 26 313 4.3E-68 T 13-09-2016 THL1_RS07420 5fb9ed15d9cb947df21348dcaf8541e1 321 Pfam PF03466 LysR substrate binding domain 113 314 3.5E-20 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS07420 5fb9ed15d9cb947df21348dcaf8541e1 321 Gene3D G3DSA:1.10.10.10 27 107 4.0E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07420 5fb9ed15d9cb947df21348dcaf8541e1 321 PANTHER PTHR30126:SF16 26 313 4.3E-68 T 13-09-2016 THL1_RS07420 5fb9ed15d9cb947df21348dcaf8541e1 321 SUPERFAMILY SSF53850 113 313 9.23E-21 T 13-09-2016 THL1_RS07420 5fb9ed15d9cb947df21348dcaf8541e1 321 Gene3D G3DSA:3.40.190.10 115 222 1.1E-8 T 13-09-2016 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR00418 DNA topoisomerase II family signature 496 513 4.2E-58 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR00418 DNA topoisomerase II family signature 516 528 4.2E-58 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR00418 DNA topoisomerase II family signature 65 78 4.2E-58 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR00418 DNA topoisomerase II family signature 413 427 4.2E-58 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR00418 DNA topoisomerase II family signature 265 278 4.2E-58 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR00418 DNA topoisomerase II family signature 30 45 4.2E-58 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR00418 DNA topoisomerase II family signature 108 122 4.2E-58 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR00418 DNA topoisomerase II family signature 561 577 4.2E-58 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR00418 DNA topoisomerase II family signature 478 494 4.2E-58 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 SUPERFAMILY SSF55874 4 214 2.6E-67 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 SUPERFAMILY SSF54211 216 381 6.83E-45 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 Gene3D G3DSA:3.40.50.670 397 610 7.9E-77 T 13-09-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 ProSitePatterns PS00177 DNA topoisomerase II signature. 415 423 - T 13-09-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 SMART SM00433 33 623 1.6E-206 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 SMART SM00387 26 172 1.1E-20 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 Pfam PF00204 DNA gyrase B 217 384 7.8E-39 T 13-09-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 Pfam PF01751 Toprim domain 412 521 8.0E-13 T 13-09-2016 IPR006171 Toprim domain THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 Gene3D G3DSA:3.30.230.10 215 389 1.1E-45 T 13-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 2 623 0.0 T 13-09-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR01098 Topoisomerase IV subunit B signature 536 558 6.5E-116 T 13-09-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR01098 Topoisomerase IV subunit B signature 191 212 6.5E-116 T 13-09-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR01098 Topoisomerase IV subunit B signature 310 325 6.5E-116 T 13-09-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR01098 Topoisomerase IV subunit B signature 447 468 6.5E-116 T 13-09-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR01098 Topoisomerase IV subunit B signature 237 260 6.5E-116 T 13-09-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR01098 Topoisomerase IV subunit B signature 468 480 6.5E-116 T 13-09-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR01098 Topoisomerase IV subunit B signature 502 518 6.5E-116 T 13-09-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR01098 Topoisomerase IV subunit B signature 361 386 6.5E-116 T 13-09-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR01098 Topoisomerase IV subunit B signature 134 148 6.5E-116 T 13-09-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR01098 Topoisomerase IV subunit B signature 148 163 6.5E-116 T 13-09-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR01098 Topoisomerase IV subunit B signature 293 309 6.5E-116 T 13-09-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR01098 Topoisomerase IV subunit B signature 25 38 6.5E-116 T 13-09-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR01098 Topoisomerase IV subunit B signature 173 190 6.5E-116 T 13-09-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR01098 Topoisomerase IV subunit B signature 337 360 6.5E-116 T 13-09-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PRINTS PR01098 Topoisomerase IV subunit B signature 583 597 6.5E-116 T 13-09-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 557 619 1.8E-24 T 13-09-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PANTHER PTHR10169:SF45 3 628 0.0 T 13-09-2016 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 Gene3D G3DSA:3.30.565.10 14 212 1.2E-75 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 SUPERFAMILY SSF56719 387 620 2.88E-76 T 13-09-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 170 5.2E-19 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 PANTHER PTHR10169 3 628 0.0 T 13-09-2016 THL1_RS25970 fedbcf2e54c251d41ddd9ce41a2d66a3 629 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 1 627 46.93 T 13-09-2016 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS06315 bab5f3cca20f14c4f7736b00b78945e3 436 Gene3D G3DSA:3.40.50.720 235 424 1.4E-39 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS06315 bab5f3cca20f14c4f7736b00b78945e3 436 SUPERFAMILY SSF52413 305 425 1.57E-23 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS06315 bab5f3cca20f14c4f7736b00b78945e3 436 SUPERFAMILY SSF51735 1 195 6.54E-51 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS06315 bab5f3cca20f14c4f7736b00b78945e3 436 PIRSF PIRSF500135 1 436 1.4E-242 T 13-09-2016 IPR028358 GDP-mannose 6-dehydrogenase GO:0042121|GO:0047919 KEGG: 00040+1.1.1.13|KEGG: 00051+1.1.1.132|KEGG: 00520+1.1.1.132|MetaCyc: PWY-6073|MetaCyc: PWY-6082|UniPathway: UPA00286 THL1_RS06315 bab5f3cca20f14c4f7736b00b78945e3 436 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 406 1.4E-12 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS06315 bab5f3cca20f14c4f7736b00b78945e3 436 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 205 298 5.7E-28 T 13-09-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 THL1_RS06315 bab5f3cca20f14c4f7736b00b78945e3 436 Gene3D G3DSA:1.20.5.100 203 234 1.6E-12 T 13-09-2016 THL1_RS06315 bab5f3cca20f14c4f7736b00b78945e3 436 SMART SM00984 317 425 1.6E-17 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS06315 bab5f3cca20f14c4f7736b00b78945e3 436 Gene3D G3DSA:3.40.50.720 1 194 6.2E-69 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS06315 bab5f3cca20f14c4f7736b00b78945e3 436 SUPERFAMILY SSF48179 204 299 1.36E-26 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS06315 bab5f3cca20f14c4f7736b00b78945e3 436 PANTHER PTHR11374 1 403 1.9E-239 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS06315 bab5f3cca20f14c4f7736b00b78945e3 436 PIRSF PIRSF000124 1 436 1.1E-136 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS06315 bab5f3cca20f14c4f7736b00b78945e3 436 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 418 2.6E-133 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS06315 bab5f3cca20f14c4f7736b00b78945e3 436 PANTHER PTHR11374:SF22 1 403 1.9E-239 T 13-09-2016 THL1_RS06315 bab5f3cca20f14c4f7736b00b78945e3 436 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 189 7.5E-64 T 13-09-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS25340 9da74be373d1477e9043cdcf7a536e09 423 PANTHER PTHR30258 53 408 1.2E-115 T 13-09-2016 THL1_RS25340 9da74be373d1477e9043cdcf7a536e09 423 Gene3D G3DSA:3.40.50.300 193 400 4.1E-58 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25340 9da74be373d1477e9043cdcf7a536e09 423 SUPERFAMILY SSF52540 72 381 1.87E-57 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25340 9da74be373d1477e9043cdcf7a536e09 423 Pfam PF00437 Type II/IV secretion system protein 91 366 1.2E-87 T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS25340 9da74be373d1477e9043cdcf7a536e09 423 PANTHER PTHR30258:SF3 53 408 1.2E-115 T 13-09-2016 THL1_RS25340 9da74be373d1477e9043cdcf7a536e09 423 Gene3D G3DSA:3.30.450.90 87 184 1.2E-35 T 13-09-2016 THL1_RS01645 2935fa6e57724e4b353e6ec5e0460b46 387 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 1.3E-78 T 13-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 THL1_RS01645 2935fa6e57724e4b353e6ec5e0460b46 387 PRINTS PR00477 Phosphoglycerate kinase family signature 132 154 1.3E-78 T 13-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 THL1_RS01645 2935fa6e57724e4b353e6ec5e0460b46 387 PRINTS PR00477 Phosphoglycerate kinase family signature 186 205 1.3E-78 T 13-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 THL1_RS01645 2935fa6e57724e4b353e6ec5e0460b46 387 PRINTS PR00477 Phosphoglycerate kinase family signature 336 347 1.3E-78 T 13-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 THL1_RS01645 2935fa6e57724e4b353e6ec5e0460b46 387 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 1.3E-78 T 13-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 THL1_RS01645 2935fa6e57724e4b353e6ec5e0460b46 387 PRINTS PR00477 Phosphoglycerate kinase family signature 359 376 1.3E-78 T 13-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 THL1_RS01645 2935fa6e57724e4b353e6ec5e0460b46 387 PRINTS PR00477 Phosphoglycerate kinase family signature 104 119 1.3E-78 T 13-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 THL1_RS01645 2935fa6e57724e4b353e6ec5e0460b46 387 PRINTS PR00477 Phosphoglycerate kinase family signature 303 328 1.3E-78 T 13-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 THL1_RS01645 2935fa6e57724e4b353e6ec5e0460b46 387 PRINTS PR00477 Phosphoglycerate kinase family signature 163 185 1.3E-78 T 13-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 THL1_RS01645 2935fa6e57724e4b353e6ec5e0460b46 387 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 13-09-2016 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 THL1_RS01645 2935fa6e57724e4b353e6ec5e0460b46 387 Pfam PF00162 Phosphoglycerate kinase 6 373 2.9E-138 T 13-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 THL1_RS01645 2935fa6e57724e4b353e6ec5e0460b46 387 PIRSF PIRSF000724 1 387 1.3E-131 T 13-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 THL1_RS01645 2935fa6e57724e4b353e6ec5e0460b46 387 Gene3D G3DSA:3.40.50.1270 175 371 4.1E-81 T 13-09-2016 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 THL1_RS01645 2935fa6e57724e4b353e6ec5e0460b46 387 PANTHER PTHR11406 1 387 6.8E-197 T 13-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 THL1_RS01645 2935fa6e57724e4b353e6ec5e0460b46 387 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 383 38.658 T 13-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 THL1_RS01645 2935fa6e57724e4b353e6ec5e0460b46 387 Gene3D G3DSA:3.40.50.1260 5 174 2.0E-63 T 13-09-2016 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 THL1_RS01645 2935fa6e57724e4b353e6ec5e0460b46 387 SUPERFAMILY SSF53748 4 383 1.3E-143 T 13-09-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 THL1_RS08580 3fc3cefb5b3b71ca33cbe518620208f6 261 Pfam PF01261 Xylose isomerase-like TIM barrel 22 212 8.7E-23 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS08580 3fc3cefb5b3b71ca33cbe518620208f6 261 PANTHER PTHR12110 1 256 1.5E-56 T 13-09-2016 THL1_RS08580 3fc3cefb5b3b71ca33cbe518620208f6 261 PANTHER PTHR12110:SF22 1 256 1.5E-56 T 13-09-2016 THL1_RS08580 3fc3cefb5b3b71ca33cbe518620208f6 261 SUPERFAMILY SSF51658 1 255 1.04E-68 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS08580 3fc3cefb5b3b71ca33cbe518620208f6 261 PIRSF PIRSF006241 1 260 2.1E-79 T 13-09-2016 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 THL1_RS08580 3fc3cefb5b3b71ca33cbe518620208f6 261 Gene3D G3DSA:3.20.20.150 1 255 7.2E-72 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 Gene3D G3DSA:3.30.450.40 192 367 2.8E-21 T 13-09-2016 IPR029016 GAF domain-like THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 Gene3D G3DSA:3.30.450.40 16 191 1.7E-21 T 13-09-2016 IPR029016 GAF domain-like THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 377 534 4.3E-23 T 13-09-2016 IPR000160 GGDEF domain THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 Pfam PF00990 Diguanylate cyclase, GGDEF domain 380 533 4.3E-27 T 13-09-2016 IPR000160 GGDEF domain THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 PANTHER PTHR33121:SF13 502 798 3.1E-79 T 13-09-2016 THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 Pfam PF13185 GAF domain 217 360 1.9E-12 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 Pfam PF13185 GAF domain 31 178 7.7E-15 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 PANTHER PTHR33121 502 798 3.1E-79 T 13-09-2016 THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 SUPERFAMILY SSF55781 219 368 7.85E-13 T 13-09-2016 IPR029016 GAF domain-like THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 PANTHER PTHR33121 290 306 3.1E-79 T 13-09-2016 THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 PANTHER PTHR33121:SF13 290 306 3.1E-79 T 13-09-2016 THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 SMART SM00065 33 187 0.0013 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 SMART SM00065 205 370 0.0094 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 Pfam PF00563 EAL domain 556 789 4.3E-69 T 13-09-2016 IPR001633 EAL domain THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 SUPERFAMILY SSF55073 385 536 1.65E-30 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 SUPERFAMILY SSF55781 33 190 2.4E-15 T 13-09-2016 IPR029016 GAF domain-like THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 SMART SM00267 369 540 8.4E-29 T 13-09-2016 IPR000160 GGDEF domain THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 SUPERFAMILY SSF141868 555 800 8.63E-86 T 13-09-2016 IPR001633 EAL domain THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 Gene3D G3DSA:3.20.20.450 553 798 3.2E-94 T 13-09-2016 IPR001633 EAL domain THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 Gene3D G3DSA:3.30.70.270 382 543 7.0E-33 T 13-09-2016 THL1_RS21040 78f436a008ae40375415cb23bc7ffa02 805 SMART SM00052 549 794 3.4E-107 T 13-09-2016 IPR001633 EAL domain THL1_RS10695 422b8f60f5941e9ed657bd5fc947de24 403 PANTHER PTHR30578 3 403 1.1E-251 T 13-09-2016 THL1_RS10695 422b8f60f5941e9ed657bd5fc947de24 403 TIGRFAM TIGR01937 nqrB: NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit 3 398 4.9E-193 T 13-09-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 THL1_RS10695 422b8f60f5941e9ed657bd5fc947de24 403 PANTHER PTHR30578:SF1 3 403 1.1E-251 T 13-09-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 THL1_RS10695 422b8f60f5941e9ed657bd5fc947de24 403 Pfam PF03116 NQR2, RnfD, RnfE family 41 395 2.8E-110 T 13-09-2016 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 THL1_RS10695 422b8f60f5941e9ed657bd5fc947de24 403 PIRSF PIRSF016055 1 403 1.1E-203 T 13-09-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 THL1_RS10695 422b8f60f5941e9ed657bd5fc947de24 403 Hamap MF_00426 Na(+)-translocating NADH-quinone reductase subunit B [nqrB]. 2 402 37.716 T 13-09-2016 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B GO:0009276|GO:0010181|GO:0016021|GO:0016655|GO:0022904|GO:0055114 THL1_RS18470 5611094cad9bca6042f0789a34964ee5 249 SUPERFAMILY SSF52402 1 242 3.28E-84 T 13-09-2016 THL1_RS18470 5611094cad9bca6042f0789a34964ee5 249 Pfam PF01012 Electron transfer flavoprotein domain 29 206 3.5E-45 T 13-09-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 THL1_RS18470 5611094cad9bca6042f0789a34964ee5 249 PANTHER PTHR21294 1 249 4.5E-150 T 13-09-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 THL1_RS18470 5611094cad9bca6042f0789a34964ee5 249 Gene3D G3DSA:3.40.50.620 1 247 1.2E-102 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS18470 5611094cad9bca6042f0789a34964ee5 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 13-09-2016 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 THL1_RS18470 5611094cad9bca6042f0789a34964ee5 249 PIRSF PIRSF000090 1 249 1.1E-82 T 13-09-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 THL1_RS18470 5611094cad9bca6042f0789a34964ee5 249 PANTHER PTHR21294:SF8 1 249 4.5E-150 T 13-09-2016 THL1_RS18470 5611094cad9bca6042f0789a34964ee5 249 SMART SM00893 23 211 1.2E-67 T 13-09-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 THL1_RS23515 88d8424275dd559a0ef2447699bb5961 363 Gene3D G3DSA:3.40.50.970 5 348 1.7E-121 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS23515 88d8424275dd559a0ef2447699bb5961 363 SUPERFAMILY SSF52518 24 352 2.5E-96 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS23515 88d8424275dd559a0ef2447699bb5961 363 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 9 349 9.1E-140 T 13-09-2016 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 THL1_RS23515 88d8424275dd559a0ef2447699bb5961 363 PANTHER PTHR11516:SF1 2 358 3.1E-122 T 13-09-2016 THL1_RS23515 88d8424275dd559a0ef2447699bb5961 363 PANTHER PTHR11516 2 358 3.1E-122 T 13-09-2016 THL1_RS23515 88d8424275dd559a0ef2447699bb5961 363 Pfam PF00676 Dehydrogenase E1 component 37 327 4.4E-80 T 13-09-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 THL1_RS07440 3851fc4d8c63c4357cefcf2d575d65eb 444 Gene3D G3DSA:3.10.20.70 5 101 1.7E-16 T 13-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS07440 3851fc4d8c63c4357cefcf2d575d65eb 444 SMART SM01230 99 354 1.7E-110 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS07440 3851fc4d8c63c4357cefcf2d575d65eb 444 SUPERFAMILY SSF55931 100 442 6.54E-112 T 13-09-2016 THL1_RS07440 3851fc4d8c63c4357cefcf2d575d65eb 444 PANTHER PTHR20852:SF7 7 444 6.3E-136 T 13-09-2016 THL1_RS07440 3851fc4d8c63c4357cefcf2d575d65eb 444 Pfam PF00120 Glutamine synthetase, catalytic domain 100 440 9.2E-112 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS07440 3851fc4d8c63c4357cefcf2d575d65eb 444 TIGRFAM TIGR03105 gln_synth_III: glutamine synthetase, type III 7 441 1.9E-202 T 13-09-2016 IPR017536 Glutamine synthetase, type III GO:0004356|GO:0006542 THL1_RS07440 3851fc4d8c63c4357cefcf2d575d65eb 444 PANTHER PTHR20852 7 444 6.3E-136 T 13-09-2016 THL1_RS07440 3851fc4d8c63c4357cefcf2d575d65eb 444 SUPERFAMILY SSF54368 4 97 9.55E-20 T 13-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS07440 3851fc4d8c63c4357cefcf2d575d65eb 444 Gene3D G3DSA:3.30.590.10 102 432 2.9E-108 T 13-09-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 THL1_RS03545 df8ba4da6a82bc542d8e6bbd76c0a9b9 91 SUPERFAMILY SSF54570 3 84 2.88E-34 T 13-09-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 THL1_RS03545 df8ba4da6a82bc542d8e6bbd76c0a9b9 91 Pfam PF00203 Ribosomal protein S19 3 83 1.4E-35 T 13-09-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 THL1_RS03545 df8ba4da6a82bc542d8e6bbd76c0a9b9 91 Gene3D G3DSA:3.30.860.10 2 90 4.6E-39 T 13-09-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 THL1_RS03545 df8ba4da6a82bc542d8e6bbd76c0a9b9 91 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 2 91 3.6E-43 T 13-09-2016 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 THL1_RS03545 df8ba4da6a82bc542d8e6bbd76c0a9b9 91 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 13-09-2016 IPR020934 Ribosomal protein S19 conserved site GO:0003723 THL1_RS03545 df8ba4da6a82bc542d8e6bbd76c0a9b9 91 PIRSF PIRSF002144 1 91 2.1E-31 T 13-09-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 THL1_RS03545 df8ba4da6a82bc542d8e6bbd76c0a9b9 91 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 1.2E-22 T 13-09-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 THL1_RS03545 df8ba4da6a82bc542d8e6bbd76c0a9b9 91 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 1.2E-22 T 13-09-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 THL1_RS03545 df8ba4da6a82bc542d8e6bbd76c0a9b9 91 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 1.2E-22 T 13-09-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 THL1_RS03545 df8ba4da6a82bc542d8e6bbd76c0a9b9 91 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 24.783 T 13-09-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 THL1_RS03545 df8ba4da6a82bc542d8e6bbd76c0a9b9 91 PANTHER PTHR11880 2 91 3.2E-52 T 13-09-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 THL1_RS03865 96a38e5498e8338978d3450b19379ba1 157 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 19 145 7.2E-42 T 13-09-2016 IPR011605 NusB antitermination factor GO:0006353 THL1_RS03865 96a38e5498e8338978d3450b19379ba1 157 Gene3D G3DSA:1.10.940.10 18 151 1.6E-42 T 13-09-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 THL1_RS03865 96a38e5498e8338978d3450b19379ba1 157 PANTHER PTHR11078 11 151 9.3E-46 T 13-09-2016 IPR011605 NusB antitermination factor GO:0006353 THL1_RS03865 96a38e5498e8338978d3450b19379ba1 157 Pfam PF01029 NusB family 20 144 1.3E-32 T 13-09-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 THL1_RS03865 96a38e5498e8338978d3450b19379ba1 157 SUPERFAMILY SSF48013 17 148 3.14E-41 T 13-09-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 THL1_RS03865 96a38e5498e8338978d3450b19379ba1 157 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 17 148 22.348 T 13-09-2016 IPR011605 NusB antitermination factor GO:0006353 THL1_RS23975 3943b1a753e2de30e36a13f4778ac3a5 360 SMART SM00937 65 180 8.4E-70 T 13-09-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 THL1_RS23975 3943b1a753e2de30e36a13f4778ac3a5 360 SUPERFAMILY SSF75620 12 355 5.23E-135 T 13-09-2016 THL1_RS23975 3943b1a753e2de30e36a13f4778ac3a5 360 PANTHER PTHR11075:SF9 1 358 1.1E-178 T 13-09-2016 THL1_RS23975 3943b1a753e2de30e36a13f4778ac3a5 360 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 230 246 - T 13-09-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THL1_RS23975 3943b1a753e2de30e36a13f4778ac3a5 360 Gene3D G3DSA:3.30.160.20 213 291 1.0E-36 T 13-09-2016 IPR014720 Double-stranded RNA-binding domain THL1_RS23975 3943b1a753e2de30e36a13f4778ac3a5 360 PANTHER PTHR11075 1 358 1.1E-178 T 13-09-2016 THL1_RS23975 3943b1a753e2de30e36a13f4778ac3a5 360 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 358 3.7E-168 T 13-09-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 THL1_RS23975 3943b1a753e2de30e36a13f4778ac3a5 360 Gene3D G3DSA:1.20.58.410 8 95 1.3E-18 T 13-09-2016 THL1_RS23975 3943b1a753e2de30e36a13f4778ac3a5 360 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 359 41.108 T 13-09-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 THL1_RS23975 3943b1a753e2de30e36a13f4778ac3a5 360 Pfam PF00472 RF-1 domain 215 323 2.5E-42 T 13-09-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THL1_RS23975 3943b1a753e2de30e36a13f4778ac3a5 360 Pfam PF03462 PCRF domain 12 205 5.9E-74 T 13-09-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 THL1_RS06390 884b7ded527bd7e88a4237b8419a04fa 491 PANTHER PTHR24031:SF261 90 483 1.1E-171 T 13-09-2016 THL1_RS06390 884b7ded527bd7e88a4237b8419a04fa 491 SMART SM00490 364 445 2.8E-32 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS06390 884b7ded527bd7e88a4237b8419a04fa 491 SUPERFAMILY SSF52540 177 461 9.82E-72 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06390 884b7ded527bd7e88a4237b8419a04fa 491 Pfam PF00271 Helicase conserved C-terminal domain 336 445 2.7E-29 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS06390 884b7ded527bd7e88a4237b8419a04fa 491 SMART SM00487 121 328 4.7E-52 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS06390 884b7ded527bd7e88a4237b8419a04fa 491 Hamap MF_00661 ATP-dependent RNA helicase RhlB [rhlB]. 101 483 52.875 T 13-09-2016 IPR023554 ATP-dependent RNA helicase RhlB type GO:0004004 THL1_RS06390 884b7ded527bd7e88a4237b8419a04fa 491 Pfam PF00270 DEAD/DEAH box helicase 126 301 6.7E-48 T 13-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THL1_RS06390 884b7ded527bd7e88a4237b8419a04fa 491 Gene3D G3DSA:3.40.50.300 97 319 5.5E-78 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06390 884b7ded527bd7e88a4237b8419a04fa 491 PANTHER PTHR24031 90 483 1.1E-171 T 13-09-2016 THL1_RS06390 884b7ded527bd7e88a4237b8419a04fa 491 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 257 265 - T 13-09-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site THL1_RS06390 884b7ded527bd7e88a4237b8419a04fa 491 Gene3D G3DSA:3.40.50.300 320 474 8.5E-50 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00300 71335c284524544fcccfb33ad5943a3e 258 PANTHER PTHR30429:SF0 1 258 2.5E-137 T 13-09-2016 THL1_RS00300 71335c284524544fcccfb33ad5943a3e 258 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 19 257 1.8E-68 T 13-09-2016 IPR004872 Lipoprotein NlpA family THL1_RS00300 71335c284524544fcccfb33ad5943a3e 258 Pfam PF03180 NLPA lipoprotein 21 258 1.7E-98 T 13-09-2016 IPR004872 Lipoprotein NlpA family THL1_RS00300 71335c284524544fcccfb33ad5943a3e 258 PIRSF PIRSF002854 1 258 3.0E-102 T 13-09-2016 IPR004872 Lipoprotein NlpA family THL1_RS00300 71335c284524544fcccfb33ad5943a3e 258 Gene3D G3DSA:3.40.190.10 19 150 6.2E-55 T 13-09-2016 THL1_RS00300 71335c284524544fcccfb33ad5943a3e 258 PANTHER PTHR30429 1 258 2.5E-137 T 13-09-2016 IPR004872 Lipoprotein NlpA family THL1_RS00300 71335c284524544fcccfb33ad5943a3e 258 SUPERFAMILY SSF53850 20 258 2.29E-83 T 13-09-2016 THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 Gene3D G3DSA:3.30.70.270 824 995 9.9E-56 T 13-09-2016 THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 SUPERFAMILY SSF55073 827 990 6.98E-47 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 SUPERFAMILY SSF141868 1004 1251 9.29E-92 T 13-09-2016 IPR001633 EAL domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 Pfam PF08448 PAS fold 700 813 1.5E-11 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 SMART SM00086 521 562 0.13 T 13-09-2016 IPR001610 PAC motif THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 SMART SM00086 647 689 0.0052 T 13-09-2016 IPR001610 PAC motif THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 SMART SM00086 387 428 3.9E-8 T 13-09-2016 IPR001610 PAC motif THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 SMART SM00086 771 811 20.0 T 13-09-2016 IPR001610 PAC motif THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 SUPERFAMILY SSF55785 688 809 1.77E-18 T 13-09-2016 IPR000014 PAS domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 319 435 1.3E-19 T 13-09-2016 IPR000014 PAS domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 690 817 2.1E-16 T 13-09-2016 IPR000014 PAS domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 571 694 1.8E-13 T 13-09-2016 IPR000014 PAS domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 SMART SM00052 998 1243 6.7E-116 T 13-09-2016 IPR001633 EAL domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 Gene3D G3DSA:3.30.450.20 560 687 3.3E-15 T 13-09-2016 THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 Gene3D G3DSA:3.30.450.20 688 809 3.3E-19 T 13-09-2016 THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 Pfam PF00563 EAL domain 1004 1238 2.9E-79 T 13-09-2016 IPR001633 EAL domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 SMART SM00267 811 988 6.2E-61 T 13-09-2016 IPR000160 GGDEF domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 818 986 1.1E-41 T 13-09-2016 IPR000160 GGDEF domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 PANTHER PTHR33121:SF13 939 1259 3.8E-93 T 13-09-2016 THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 PANTHER PTHR33121 939 1259 3.8E-93 T 13-09-2016 THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 Gene3D G3DSA:3.30.450.20 324 428 1.7E-31 T 13-09-2016 THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 Pfam PF13426 PAS domain 332 426 2.5E-16 T 13-09-2016 IPR000014 PAS domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 Pfam PF13426 PAS domain 586 687 2.2E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 SUPERFAMILY SSF55785 456 565 2.79E-10 T 13-09-2016 IPR000014 PAS domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 Pfam PF00990 Diguanylate cyclase, GGDEF domain 822 983 1.2E-47 T 13-09-2016 IPR000160 GGDEF domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 SMART SM00091 694 761 4.2E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 SMART SM00091 574 640 0.0041 T 13-09-2016 IPR000014 PAS domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 SMART SM00091 312 381 1.6E-9 T 13-09-2016 IPR000014 PAS domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 SUPERFAMILY SSF55785 560 687 1.31E-14 T 13-09-2016 IPR000014 PAS domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 Gene3D G3DSA:3.20.20.450 1001 1250 2.1E-101 T 13-09-2016 IPR001633 EAL domain THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 Gene3D G3DSA:3.30.450.20 439 559 1.6E-13 T 13-09-2016 THL1_RS27130 165ecbd2d2cf915da80d3ee340338829 1261 SUPERFAMILY SSF55785 320 428 2.26E-25 T 13-09-2016 IPR000014 PAS domain THL1_RS05925 7f7cf549bdb5dd113067f6e15caa1972 165 PANTHER PTHR33221:SF1 2 152 4.0E-74 T 13-09-2016 THL1_RS05925 7f7cf549bdb5dd113067f6e15caa1972 165 Gene3D G3DSA:1.10.10.10 1 135 1.3E-31 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS05925 7f7cf549bdb5dd113067f6e15caa1972 165 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 8.8E-47 T 13-09-2016 IPR000944 Transcription regulator Rrf2-type THL1_RS05925 7f7cf549bdb5dd113067f6e15caa1972 165 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 134 7.0E-67 T 13-09-2016 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 THL1_RS05925 7f7cf549bdb5dd113067f6e15caa1972 165 Pfam PF02082 Transcriptional regulator 1 83 7.2E-28 T 13-09-2016 IPR000944 Transcription regulator Rrf2-type THL1_RS05925 7f7cf549bdb5dd113067f6e15caa1972 165 SUPERFAMILY SSF46785 2 133 3.89E-36 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS05925 7f7cf549bdb5dd113067f6e15caa1972 165 PANTHER PTHR33221 2 152 4.0E-74 T 13-09-2016 THL1_RS11380 b2cba346ac31dc073612ac22799ee295 323 PANTHER PTHR21535:SF33 13 323 5.0E-48 T 13-09-2016 THL1_RS11380 b2cba346ac31dc073612ac22799ee295 323 Gene3D G3DSA:1.20.58.340 133 244 1.0E-35 T 13-09-2016 THL1_RS11380 b2cba346ac31dc073612ac22799ee295 323 PANTHER PTHR21535 13 323 5.0E-48 T 13-09-2016 THL1_RS11380 b2cba346ac31dc073612ac22799ee295 323 Pfam PF01544 CorA-like Mg2+ transporter protein 33 314 3.4E-55 T 13-09-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 THL1_RS11380 b2cba346ac31dc073612ac22799ee295 323 SUPERFAMILY SSF143865 5 250 6.54E-65 T 13-09-2016 THL1_RS11380 b2cba346ac31dc073612ac22799ee295 323 Gene3D G3DSA:3.30.460.20 6 132 2.9E-29 T 13-09-2016 THL1_RS11380 b2cba346ac31dc073612ac22799ee295 323 Gene3D G3DSA:1.20.58.340 253 323 5.3E-21 T 13-09-2016 THL1_RS11380 b2cba346ac31dc073612ac22799ee295 323 SUPERFAMILY SSF144083 259 320 2.48E-16 T 13-09-2016 THL1_RS25030 a7320003e4eb8e89335dddd7708fd00c 291 Pfam PF03934 Type II secretion system (T2SS), protein K 32 135 5.0E-21 T 13-09-2016 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 THL1_RS25030 a7320003e4eb8e89335dddd7708fd00c 291 Pfam PF03934 Type II secretion system (T2SS), protein K 151 275 1.4E-27 T 13-09-2016 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 THL1_RS25030 a7320003e4eb8e89335dddd7708fd00c 291 SUPERFAMILY SSF54523 40 105 1.13E-19 T 13-09-2016 THL1_RS25030 a7320003e4eb8e89335dddd7708fd00c 291 SUPERFAMILY SSF54523 244 281 1.13E-19 T 13-09-2016 THL1_RS25030 a7320003e4eb8e89335dddd7708fd00c 291 Gene3D G3DSA:1.10.40.60 186 235 1.0E-10 T 13-09-2016 THL1_RS25030 a7320003e4eb8e89335dddd7708fd00c 291 SUPERFAMILY SSF158544 186 236 1.6E-7 T 13-09-2016 THL1_RS25030 a7320003e4eb8e89335dddd7708fd00c 291 Gene3D G3DSA:3.30.1300.30 245 282 9.3E-25 T 13-09-2016 THL1_RS25030 a7320003e4eb8e89335dddd7708fd00c 291 Gene3D G3DSA:3.30.1300.30 29 103 9.3E-25 T 13-09-2016 THL1_RS23610 1be81d3b1ab37d131984e2661aa00b2b 123 TIGRFAM TIGR00526 folB_dom: FolB domain 8 119 1.9E-32 T 13-09-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 THL1_RS23610 1be81d3b1ab37d131984e2661aa00b2b 123 SMART SM00905 11 121 6.7E-34 T 13-09-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 THL1_RS23610 1be81d3b1ab37d131984e2661aa00b2b 123 PANTHER PTHR20941:SF6 1 119 4.5E-65 T 13-09-2016 THL1_RS23610 1be81d3b1ab37d131984e2661aa00b2b 123 PANTHER PTHR20941 1 119 4.5E-65 T 13-09-2016 THL1_RS23610 1be81d3b1ab37d131984e2661aa00b2b 123 Gene3D G3DSA:3.30.1130.10 7 119 7.2E-37 T 13-09-2016 THL1_RS23610 1be81d3b1ab37d131984e2661aa00b2b 123 Pfam PF02152 Dihydroneopterin aldolase 11 119 6.7E-27 T 13-09-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 THL1_RS23610 1be81d3b1ab37d131984e2661aa00b2b 123 SUPERFAMILY SSF55620 7 120 3.3E-31 T 13-09-2016 THL1_RS01180 0c4f5c6c59b04adc63d1c78f96fbed4a 205 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 63 77 1.6E-5 T 13-09-2016 THL1_RS01180 0c4f5c6c59b04adc63d1c78f96fbed4a 205 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 129 141 1.6E-5 T 13-09-2016 THL1_RS01180 0c4f5c6c59b04adc63d1c78f96fbed4a 205 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 38 54 1.6E-5 T 13-09-2016 THL1_RS01180 0c4f5c6c59b04adc63d1c78f96fbed4a 205 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 10 197 7.9E-52 T 13-09-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS01180 0c4f5c6c59b04adc63d1c78f96fbed4a 205 PANTHER PTHR18895:SF60 18 201 2.0E-42 T 13-09-2016 THL1_RS01180 0c4f5c6c59b04adc63d1c78f96fbed4a 205 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 132 138 - T 13-09-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THL1_RS01180 0c4f5c6c59b04adc63d1c78f96fbed4a 205 PANTHER PTHR18895 18 201 2.0E-42 T 13-09-2016 THL1_RS01180 0c4f5c6c59b04adc63d1c78f96fbed4a 205 Gene3D G3DSA:3.40.50.150 13 198 2.0E-59 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS01180 0c4f5c6c59b04adc63d1c78f96fbed4a 205 PIRSF PIRSF004553 18 199 2.6E-49 T 13-09-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS01180 0c4f5c6c59b04adc63d1c78f96fbed4a 205 Pfam PF03602 Conserved hypothetical protein 95 19 195 1.8E-57 T 13-09-2016 THL1_RS01180 0c4f5c6c59b04adc63d1c78f96fbed4a 205 SUPERFAMILY SSF53335 19 197 8.37E-51 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS00310 54b848d9513af2489a00eff82682080d 335 Pfam PF00005 ABC transporter 22 170 3.8E-36 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS00310 54b848d9513af2489a00eff82682080d 335 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS00310 54b848d9513af2489a00eff82682080d 335 Gene3D G3DSA:3.30.70.260 237 334 4.3E-24 T 13-09-2016 THL1_RS00310 54b848d9513af2489a00eff82682080d 335 SUPERFAMILY SSF55021 262 334 1.72E-16 T 13-09-2016 THL1_RS00310 54b848d9513af2489a00eff82682080d 335 PANTHER PTHR24220:SF455 277 308 2.3E-157 T 13-09-2016 IPR026253 Methionine import ATP-binding protein MetN GO:0005524|GO:0015821|GO:0042626 THL1_RS00310 54b848d9513af2489a00eff82682080d 335 Pfam PF09383 NIL domain 263 332 2.0E-19 T 13-09-2016 IPR018449 NIL domain THL1_RS00310 54b848d9513af2489a00eff82682080d 335 SMART SM00930 261 334 3.8E-24 T 13-09-2016 IPR018449 NIL domain THL1_RS00310 54b848d9513af2489a00eff82682080d 335 PANTHER PTHR24220 277 308 2.3E-157 T 13-09-2016 THL1_RS00310 54b848d9513af2489a00eff82682080d 335 PANTHER PTHR24220 3 248 2.3E-157 T 13-09-2016 THL1_RS00310 54b848d9513af2489a00eff82682080d 335 PANTHER PTHR24220:SF455 3 248 2.3E-157 T 13-09-2016 IPR026253 Methionine import ATP-binding protein MetN GO:0005524|GO:0015821|GO:0042626 THL1_RS00310 54b848d9513af2489a00eff82682080d 335 SUPERFAMILY SSF52540 1 241 1.36E-82 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00310 54b848d9513af2489a00eff82682080d 335 Gene3D G3DSA:3.40.50.300 1 236 4.6E-87 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00310 54b848d9513af2489a00eff82682080d 335 SMART SM00382 30 218 6.4E-18 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS10900 9d50d047b330d261e93330540c4369cc 441 PANTHER PTHR34596 1 441 1.2E-134 T 13-09-2016 THL1_RS10900 9d50d047b330d261e93330540c4369cc 441 Pfam PF03573 outer membrane porin, OprD family 31 440 4.4E-123 T 13-09-2016 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 THL1_RS10900 9d50d047b330d261e93330540c4369cc 441 Gene3D G3DSA:2.40.160.10 35 441 6.7E-117 T 13-09-2016 IPR023614 Porin domain THL1_RS07935 865e90d7f0c152dc9c1ced3c46915930 344 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 108 324 1.8E-42 T 13-09-2016 IPR005079 Peptidase C45 THL1_RS07935 865e90d7f0c152dc9c1ced3c46915930 344 PANTHER PTHR34180 1 316 7.6E-50 T 13-09-2016 THL1_RS02095 2351a7b80751b3bedde34799e5cada13 144 Pfam PF00571 CBS domain 13 61 2.9E-10 T 13-09-2016 IPR000644 CBS domain THL1_RS02095 2351a7b80751b3bedde34799e5cada13 144 Pfam PF00571 CBS domain 74 124 1.5E-11 T 13-09-2016 IPR000644 CBS domain THL1_RS02095 2351a7b80751b3bedde34799e5cada13 144 PANTHER PTHR11911 13 143 1.0E-32 T 13-09-2016 THL1_RS02095 2351a7b80751b3bedde34799e5cada13 144 SMART SM00116 15 62 8.5E-12 T 13-09-2016 IPR000644 CBS domain THL1_RS02095 2351a7b80751b3bedde34799e5cada13 144 SMART SM00116 80 127 4.8E-6 T 13-09-2016 IPR000644 CBS domain THL1_RS02095 2351a7b80751b3bedde34799e5cada13 144 Gene3D G3DSA:3.10.580.10 12 124 3.6E-34 T 13-09-2016 THL1_RS02095 2351a7b80751b3bedde34799e5cada13 144 SUPERFAMILY SSF54631 13 128 2.65E-32 T 13-09-2016 THL1_RS01720 44b42cf4aa888d17b9ac0543410045ad 490 SUPERFAMILY SSF53720 5 484 2.75E-175 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS01720 44b42cf4aa888d17b9ac0543410045ad 490 Pfam PF00171 Aldehyde dehydrogenase family 16 479 2.3E-181 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS01720 44b42cf4aa888d17b9ac0543410045ad 490 PANTHER PTHR11699 1 490 0.0 T 13-09-2016 THL1_RS01720 44b42cf4aa888d17b9ac0543410045ad 490 Gene3D G3DSA:3.40.309.10 266 444 7.3E-70 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS01720 44b42cf4aa888d17b9ac0543410045ad 490 PANTHER PTHR11699:SF115 1 490 0.0 T 13-09-2016 THL1_RS01720 44b42cf4aa888d17b9ac0543410045ad 490 Gene3D G3DSA:3.40.605.10 6 265 3.2E-107 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS01720 44b42cf4aa888d17b9ac0543410045ad 490 Hamap MF_00804 NAD/NADP-dependent betaine aldehyde dehydrogenase [betB]. 4 490 58.889 T 13-09-2016 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494|UniPathway: UPA00529 THL1_RS01720 44b42cf4aa888d17b9ac0543410045ad 490 TIGRFAM TIGR01804 BADH: betaine-aldehyde dehydrogenase 10 477 5.4E-228 T 13-09-2016 IPR011264 Betaine aldehyde dehydrogenase GO:0008802|GO:0019285|GO:0046872 KEGG: 00260+1.2.1.8|MetaCyc: PWY-3722|MetaCyc: PWY-7494|UniPathway: UPA00529 THL1_RS01720 44b42cf4aa888d17b9ac0543410045ad 490 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS01720 44b42cf4aa888d17b9ac0543410045ad 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS13250 e168dc8e5b292063065208cf60c7fc29 964 Pfam PF13191 AAA ATPase domain 133 305 4.4E-24 T 13-09-2016 THL1_RS13250 e168dc8e5b292063065208cf60c7fc29 964 SMART SM00862 31 106 2.5E-21 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS13250 e168dc8e5b292063065208cf60c7fc29 964 Gene3D G3DSA:1.10.10.10 11 107 1.0E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13250 e168dc8e5b292063065208cf60c7fc29 964 Gene3D G3DSA:3.40.50.300 129 180 1.8E-7 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS13250 e168dc8e5b292063065208cf60c7fc29 964 SUPERFAMILY SSF52540 131 185 1.14E-10 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS13250 e168dc8e5b292063065208cf60c7fc29 964 SUPERFAMILY SSF52540 233 390 1.14E-10 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS13250 e168dc8e5b292063065208cf60c7fc29 964 PANTHER PTHR16305 799 942 2.4E-28 T 13-09-2016 THL1_RS13250 e168dc8e5b292063065208cf60c7fc29 964 PANTHER PTHR16305 128 592 2.4E-28 T 13-09-2016 THL1_RS13250 e168dc8e5b292063065208cf60c7fc29 964 Pfam PF00486 Transcriptional regulatory protein, C terminal 31 106 7.4E-19 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS13250 e168dc8e5b292063065208cf60c7fc29 964 SUPERFAMILY SSF48452 600 698 3.08E-10 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS13250 e168dc8e5b292063065208cf60c7fc29 964 SUPERFAMILY SSF46894 14 107 1.45E-20 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS13250 e168dc8e5b292063065208cf60c7fc29 964 Gene3D G3DSA:1.25.40.10 622 788 1.0E-12 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS13250 e168dc8e5b292063065208cf60c7fc29 964 Gene3D G3DSA:1.25.40.10 830 959 1.0E-12 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS14640 ca2018ad0a250f2fe5f1eba7654ad33e 179 ProSitePatterns PS00194 Thioredoxin family active site. 62 80 - T 13-09-2016 IPR017937 Thioredoxin, conserved site GO:0045454 THL1_RS14640 ca2018ad0a250f2fe5f1eba7654ad33e 179 Gene3D G3DSA:3.40.30.10 3 175 3.3E-39 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS14640 ca2018ad0a250f2fe5f1eba7654ad33e 179 Pfam PF08534 Redoxin 40 161 2.4E-16 T 13-09-2016 IPR013740 Redoxin GO:0016491 THL1_RS14640 ca2018ad0a250f2fe5f1eba7654ad33e 179 SUPERFAMILY SSF52833 12 171 5.74E-36 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS14640 ca2018ad0a250f2fe5f1eba7654ad33e 179 PANTHER PTHR10681:SF68 36 174 1.2E-17 T 13-09-2016 THL1_RS14640 ca2018ad0a250f2fe5f1eba7654ad33e 179 PANTHER PTHR10681 36 174 1.2E-17 T 13-09-2016 THL1_RS21655 6320255f3a7f19ad8c644b52f45bb6ea 331 Gene3D G3DSA:3.40.50.1820 30 319 2.0E-65 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS21655 6320255f3a7f19ad8c644b52f45bb6ea 331 PANTHER PTHR10992 117 321 1.3E-56 T 13-09-2016 THL1_RS21655 6320255f3a7f19ad8c644b52f45bb6ea 331 Pfam PF00561 alpha/beta hydrolase fold 51 301 8.3E-20 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS21655 6320255f3a7f19ad8c644b52f45bb6ea 331 SUPERFAMILY SSF53474 28 319 2.97E-60 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS21655 6320255f3a7f19ad8c644b52f45bb6ea 331 PANTHER PTHR10992:SF732 117 321 1.3E-56 T 13-09-2016 THL1_RS21655 6320255f3a7f19ad8c644b52f45bb6ea 331 PANTHER PTHR10992:SF732 28 97 1.3E-56 T 13-09-2016 THL1_RS21655 6320255f3a7f19ad8c644b52f45bb6ea 331 PANTHER PTHR10992 28 97 1.3E-56 T 13-09-2016 THL1_RS04145 3eeeb0878fcfca35763d71c467d7d6b0 96 Pfam PF07119 Protein of unknown function (DUF1375) 9 81 2.4E-22 T 13-09-2016 IPR010780 Protein of unknown function DUF1375 THL1_RS28395 c4a3d5e73139df8277869d7a135bfd12 396 PANTHER PTHR10108:SF743 309 394 5.2E-120 T 13-09-2016 THL1_RS28395 c4a3d5e73139df8277869d7a135bfd12 396 PANTHER PTHR10108:SF743 87 292 5.2E-120 T 13-09-2016 THL1_RS28395 c4a3d5e73139df8277869d7a135bfd12 396 SUPERFAMILY SSF53335 109 377 4.38E-81 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS28395 c4a3d5e73139df8277869d7a135bfd12 396 Pfam PF02353 Mycolic acid cyclopropane synthetase 99 372 1.5E-103 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS28395 c4a3d5e73139df8277869d7a135bfd12 396 PANTHER PTHR10108 309 394 5.2E-120 T 13-09-2016 THL1_RS28395 c4a3d5e73139df8277869d7a135bfd12 396 PANTHER PTHR10108 87 292 5.2E-120 T 13-09-2016 THL1_RS28395 c4a3d5e73139df8277869d7a135bfd12 396 Gene3D G3DSA:3.40.50.150 102 376 7.7E-95 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS28395 c4a3d5e73139df8277869d7a135bfd12 396 PIRSF PIRSF003085 1 394 1.2E-126 T 13-09-2016 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 THL1_RS20300 521c86601c3b64b7baf588e73b017b2c 353 Pfam PF08402 TOBE domain 279 352 5.0E-6 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS20300 521c86601c3b64b7baf588e73b017b2c 353 PANTHER PTHR24220 12 252 1.3E-117 T 13-09-2016 THL1_RS20300 521c86601c3b64b7baf588e73b017b2c 353 PANTHER PTHR24220:SF150 12 252 1.3E-117 T 13-09-2016 THL1_RS20300 521c86601c3b64b7baf588e73b017b2c 353 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS20300 521c86601c3b64b7baf588e73b017b2c 353 TIGRFAM TIGR03265 PhnT2: putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein 9 353 9.2E-158 T 13-09-2016 IPR017666 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT2 GO:0005524 THL1_RS20300 521c86601c3b64b7baf588e73b017b2c 353 Gene3D G3DSA:3.40.50.300 12 241 9.1E-80 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS20300 521c86601c3b64b7baf588e73b017b2c 353 SUPERFAMILY SSF52540 12 247 1.82E-86 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS20300 521c86601c3b64b7baf588e73b017b2c 353 SUPERFAMILY SSF50331 243 352 2.32E-8 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS20300 521c86601c3b64b7baf588e73b017b2c 353 SMART SM00382 35 216 1.6E-19 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS20300 521c86601c3b64b7baf588e73b017b2c 353 Pfam PF00005 ABC transporter 28 166 6.4E-34 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS01785 c018313de6894ee55565aaa457f95de3 410 PANTHER PTHR10909 245 396 1.1E-13 T 13-09-2016 THL1_RS01785 c018313de6894ee55565aaa457f95de3 410 SUPERFAMILY SSF52467 281 396 1.18E-32 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS01785 c018313de6894ee55565aaa457f95de3 410 Pfam PF01012 Electron transfer flavoprotein domain 102 224 1.4E-18 T 13-09-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 THL1_RS01785 c018313de6894ee55565aaa457f95de3 410 PANTHER PTHR10909:SF309 245 396 1.1E-13 T 13-09-2016 THL1_RS01785 c018313de6894ee55565aaa457f95de3 410 Gene3D G3DSA:3.40.50.1220 277 396 1.7E-36 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS01785 c018313de6894ee55565aaa457f95de3 410 SUPERFAMILY SSF52402 95 215 2.93E-19 T 13-09-2016 THL1_RS01785 c018313de6894ee55565aaa457f95de3 410 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 283 358 6.8E-24 T 13-09-2016 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal THL1_RS01785 c018313de6894ee55565aaa457f95de3 410 SMART SM00893 95 275 9.3E-7 T 13-09-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 THL1_RS01785 c018313de6894ee55565aaa457f95de3 410 Gene3D G3DSA:3.40.50.620 94 213 8.8E-14 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS22570 4486532762c2d320cb48febccdbd3769 200 Gene3D G3DSA:3.30.420.10 13 153 2.5E-50 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS22570 4486532762c2d320cb48febccdbd3769 200 PANTHER PTHR10954 11 197 6.9E-84 T 13-09-2016 IPR001352 Ribonuclease HII/HIII GO:0003723|GO:0004523 THL1_RS22570 4486532762c2d320cb48febccdbd3769 200 SUPERFAMILY SSF53098 12 197 7.89E-71 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS22570 4486532762c2d320cb48febccdbd3769 200 Pfam PF01351 Ribonuclease HII 15 190 1.8E-41 T 13-09-2016 IPR024567 Ribonuclease HII/HIII domain THL1_RS22570 4486532762c2d320cb48febccdbd3769 200 Hamap MF_00052_B Ribonuclease HII [rnhB]. 13 192 39.055 T 13-09-2016 IPR022898 Ribonuclease HII GO:0004523 THL1_RS00840 de8b548350cc771b9bb1a58d4a54dceb 260 Gene3D G3DSA:3.40.190.10 23 151 4.3E-53 T 13-09-2016 THL1_RS00840 de8b548350cc771b9bb1a58d4a54dceb 260 SUPERFAMILY SSF53850 24 260 1.14E-83 T 13-09-2016 THL1_RS00840 de8b548350cc771b9bb1a58d4a54dceb 260 Pfam PF03180 NLPA lipoprotein 25 260 8.8E-100 T 13-09-2016 IPR004872 Lipoprotein NlpA family THL1_RS00840 de8b548350cc771b9bb1a58d4a54dceb 260 PANTHER PTHR30429 1 260 4.7E-138 T 13-09-2016 IPR004872 Lipoprotein NlpA family THL1_RS00840 de8b548350cc771b9bb1a58d4a54dceb 260 PIRSF PIRSF002854 1 260 1.8E-103 T 13-09-2016 IPR004872 Lipoprotein NlpA family THL1_RS00840 de8b548350cc771b9bb1a58d4a54dceb 260 PANTHER PTHR30429:SF0 1 260 4.7E-138 T 13-09-2016 THL1_RS10810 1189a948fde1e9863059c0852a5cc83a 93 Gene3D G3DSA:2.60.120.10 1 92 6.2E-39 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS10810 1189a948fde1e9863059c0852a5cc83a 93 PANTHER PTHR36540:SF1 1 93 2.2E-46 T 13-09-2016 THL1_RS10810 1189a948fde1e9863059c0852a5cc83a 93 Pfam PF06865 Protein of unknown function (DUF1255) 3 92 2.2E-36 T 13-09-2016 IPR009664 Protein of unknown function DUF1255 THL1_RS10810 1189a948fde1e9863059c0852a5cc83a 93 SUPERFAMILY SSF51182 1 92 6.58E-36 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS10810 1189a948fde1e9863059c0852a5cc83a 93 Hamap MF_01537 UPF0345 protein YaiE [yaiE]. 1 93 25.585 T 13-09-2016 IPR009664 Protein of unknown function DUF1255 THL1_RS10810 1189a948fde1e9863059c0852a5cc83a 93 PANTHER PTHR36540 1 93 2.2E-46 T 13-09-2016 THL1_RS22560 57d8eb0843539966667120e2c662d326 316 Gene3D G3DSA:3.90.226.10 58 272 2.5E-48 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS22560 57d8eb0843539966667120e2c662d326 316 PANTHER PTHR22855:SF42 1 314 6.2E-130 T 13-09-2016 THL1_RS22560 57d8eb0843539966667120e2c662d326 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 88 99 1.4E-46 T 13-09-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS22560 57d8eb0843539966667120e2c662d326 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 153 166 1.4E-46 T 13-09-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS22560 57d8eb0843539966667120e2c662d326 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 169 182 1.4E-46 T 13-09-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS22560 57d8eb0843539966667120e2c662d326 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 113 131 1.4E-46 T 13-09-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS22560 57d8eb0843539966667120e2c662d326 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 134 150 1.4E-46 T 13-09-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS22560 57d8eb0843539966667120e2c662d326 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 197 206 1.4E-46 T 13-09-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS22560 57d8eb0843539966667120e2c662d326 316 SUPERFAMILY SSF52096 5 315 5.53E-103 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS22560 57d8eb0843539966667120e2c662d326 316 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 316 50.78 T 13-09-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS22560 57d8eb0843539966667120e2c662d326 316 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 315 2.1E-159 T 13-09-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS22560 57d8eb0843539966667120e2c662d326 316 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 148 2.9E-64 T 13-09-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS22560 57d8eb0843539966667120e2c662d326 316 PANTHER PTHR22855 1 314 6.2E-130 T 13-09-2016 THL1_RS15320 0c0998b03860de0fa32ca2f054f78588 685 PANTHER PTHR30252:SF3 5 685 0.0 T 13-09-2016 THL1_RS15320 0c0998b03860de0fa32ca2f054f78588 685 PANTHER PTHR30252 5 685 0.0 T 13-09-2016 THL1_RS15320 0c0998b03860de0fa32ca2f054f78588 685 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 463 591 4.5E-36 T 13-09-2016 IPR025299 CstA, C-terminal domain THL1_RS15320 0c0998b03860de0fa32ca2f054f78588 685 Pfam PF02554 Carbon starvation protein CstA 32 408 1.5E-167 T 13-09-2016 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 THL1_RS23030 d3883eb50bfeee9f154d0616fcdde1e8 384 PANTHER PTHR10799 160 381 4.8E-26 T 13-09-2016 THL1_RS23030 d3883eb50bfeee9f154d0616fcdde1e8 384 Gene3D G3DSA:3.30.70.270 225 381 9.4E-48 T 13-09-2016 THL1_RS23030 d3883eb50bfeee9f154d0616fcdde1e8 384 PANTHER PTHR10799:SF710 160 381 4.8E-26 T 13-09-2016 THL1_RS23030 d3883eb50bfeee9f154d0616fcdde1e8 384 SMART SM00267 212 381 3.3E-55 T 13-09-2016 IPR000160 GGDEF domain THL1_RS23030 d3883eb50bfeee9f154d0616fcdde1e8 384 Pfam PF00990 Diguanylate cyclase, GGDEF domain 223 377 1.5E-41 T 13-09-2016 IPR000160 GGDEF domain THL1_RS23030 d3883eb50bfeee9f154d0616fcdde1e8 384 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 222 379 2.7E-44 T 13-09-2016 IPR000160 GGDEF domain THL1_RS23030 d3883eb50bfeee9f154d0616fcdde1e8 384 SUPERFAMILY SSF55073 228 381 1.65E-43 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 SUPERFAMILY SSF53067 19 197 2.07E-51 T 13-09-2016 THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 SUPERFAMILY SSF100934 504 615 7.85E-34 T 13-09-2016 IPR029048 Heat shock protein 70kD, C-terminal domain THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 Gene3D G3DSA:3.30.30.30 70 118 1.1E-6 T 13-09-2016 THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 Gene3D G3DSA:3.30.420.40 314 356 1.1E-31 T 13-09-2016 THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 Gene3D G3DSA:3.30.420.40 206 238 1.1E-31 T 13-09-2016 THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 13-09-2016 IPR018181 Heat shock protein 70, conserved site THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 Gene3D G3DSA:1.20.1270.10 529 616 2.4E-29 T 13-09-2016 IPR029048 Heat shock protein 70kD, C-terminal domain THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 Gene3D G3DSA:3.90.640.10 239 308 1.7E-4 T 13-09-2016 THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 PANTHER PTHR19375 19 605 0.0 T 13-09-2016 THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 Pfam PF00012 Hsp70 protein 21 600 5.4E-184 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 105 119 - T 13-09-2016 IPR018181 Heat shock protein 70, conserved site THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 205 218 - T 13-09-2016 IPR018181 Heat shock protein 70, conserved site THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 616 8.9E-280 T 13-09-2016 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 PANTHER PTHR19375:SF176 19 605 0.0 T 13-09-2016 THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 PRINTS PR00301 70kDa heat shock protein signature 385 404 5.8E-57 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 PRINTS PR00301 70kDa heat shock protein signature 152 172 5.8E-57 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 PRINTS PR00301 70kDa heat shock protein signature 48 60 5.8E-57 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 PRINTS PR00301 70kDa heat shock protein signature 70 78 5.8E-57 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 PRINTS PR00301 70kDa heat shock protein signature 329 345 5.8E-57 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 PRINTS PR00301 70kDa heat shock protein signature 466 482 5.8E-57 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 PRINTS PR00301 70kDa heat shock protein signature 211 221 5.8E-57 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 PRINTS PR00301 70kDa heat shock protein signature 360 380 5.8E-57 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 PRINTS PR00301 70kDa heat shock protein signature 20 33 5.8E-57 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 332 346 - T 13-09-2016 IPR018181 Heat shock protein 70, conserved site THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 Gene3D G3DSA:2.60.34.10 387 528 1.1E-54 T 13-09-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 SUPERFAMILY SSF100920 384 537 9.29E-50 T 13-09-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 SUPERFAMILY SSF53067 200 376 2.39E-48 T 13-09-2016 THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 617 45.441 T 13-09-2016 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 Gene3D G3DSA:3.30.420.40 133 205 2.6E-53 T 13-09-2016 THL1_RS05950 63de7585ea5e923f9aa30a4e039ffc80 619 Gene3D G3DSA:3.30.420.40 20 69 2.6E-53 T 13-09-2016 THL1_RS03655 c9f50b6040670de8a76945cb2774ce4f 129 SUPERFAMILY SSF64263 1 119 7.33E-50 T 13-09-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03655 c9f50b6040670de8a76945cb2774ce4f 129 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 13-09-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03655 c9f50b6040670de8a76945cb2774ce4f 129 Pfam PF01196 Ribosomal protein L17 20 116 2.1E-33 T 13-09-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03655 c9f50b6040670de8a76945cb2774ce4f 129 Gene3D G3DSA:3.90.1030.10 1 117 1.4E-48 T 13-09-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03655 c9f50b6040670de8a76945cb2774ce4f 129 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 7.8E-46 T 13-09-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03655 c9f50b6040670de8a76945cb2774ce4f 129 PANTHER PTHR14413 1 119 6.8E-63 T 13-09-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03655 c9f50b6040670de8a76945cb2774ce4f 129 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 25.458 T 13-09-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS19300 47e593bba347a907a2311c26be423707 484 Pfam PF02386 Cation transport protein 44 479 6.2E-49 T 13-09-2016 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 THL1_RS19300 47e593bba347a907a2311c26be423707 484 PANTHER PTHR32024:SF3 3 483 1.1E-281 T 13-09-2016 THL1_RS19300 47e593bba347a907a2311c26be423707 484 PIRSF PIRSF006247 1 484 4.5E-169 T 13-09-2016 IPR004772 TrkH potassium transport family GO:0016021|GO:0022820|GO:0071805 THL1_RS19300 47e593bba347a907a2311c26be423707 484 PANTHER PTHR32024 3 483 1.1E-281 T 13-09-2016 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 SUPERFAMILY SSF55781 149 291 1.5E-14 T 13-09-2016 IPR029016 GAF domain-like THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 Gene3D G3DSA:3.40.50.2300 812 932 1.4E-24 T 13-09-2016 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 SMART SM00387 665 787 3.5E-29 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 Pfam PF13188 PAS domain 292 336 1.3E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 SUPERFAMILY SSF55785 402 532 1.34E-28 T 13-09-2016 IPR000014 PAS domain THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 Gene3D G3DSA:3.30.450.40 132 286 5.5E-10 T 13-09-2016 IPR029016 GAF domain-like THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 SMART SM00448 811 924 2.5E-21 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 SUPERFAMILY SSF55785 9 127 2.74E-21 T 13-09-2016 IPR000014 PAS domain THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 SUPERFAMILY SSF47384 545 625 8.24E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 Pfam PF00072 Response regulator receiver domain 813 924 5.3E-18 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 413 540 1.8E-24 T 13-09-2016 IPR000014 PAS domain THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 287 412 1.0E-19 T 13-09-2016 IPR000014 PAS domain THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 13 136 1.1E-15 T 13-09-2016 IPR000014 PAS domain THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 PANTHER PTHR24423:SF544 17 928 1.4E-128 T 13-09-2016 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 PANTHER PTHR24423 17 928 1.4E-128 T 13-09-2016 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 SUPERFAMILY SSF55874 614 785 3.54E-37 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 SMART SM00091 417 484 2.2E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 SMART SM00091 16 82 1.4E-9 T 13-09-2016 IPR000014 PAS domain THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 SMART SM00091 290 357 4.1E-4 T 13-09-2016 IPR000014 PAS domain THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 Pfam PF08448 PAS fold 22 130 2.6E-23 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 Gene3D G3DSA:1.10.287.130 549 620 3.3E-8 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 SMART SM00065 147 293 0.0017 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 Gene3D G3DSA:3.30.565.10 626 785 1.9E-37 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 Pfam PF00512 His Kinase A (phospho-acceptor) domain 558 621 1.1E-10 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 Gene3D G3DSA:3.30.450.20 403 532 1.1E-29 T 13-09-2016 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 666 785 9.1E-18 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 SUPERFAMILY SSF52172 812 929 2.13E-26 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 SUPERFAMILY SSF55785 301 413 1.77E-18 T 13-09-2016 IPR000014 PAS domain THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 PRINTS PR00344 Bacterial sensor protein C-terminal signature 734 744 7.4E-18 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 PRINTS PR00344 Bacterial sensor protein C-terminal signature 747 765 7.4E-18 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 PRINTS PR00344 Bacterial sensor protein C-terminal signature 771 784 7.4E-18 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 PRINTS PR00344 Bacterial sensor protein C-terminal signature 716 730 7.4E-18 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 Pfam PF13426 PAS domain 428 533 2.3E-11 T 13-09-2016 IPR000014 PAS domain THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 Gene3D G3DSA:3.30.450.20 287 402 1.6E-19 T 13-09-2016 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 SMART SM00388 556 624 3.4E-10 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 Gene3D G3DSA:3.30.450.20 12 129 3.4E-22 T 13-09-2016 THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 SMART SM00086 494 534 3.9 T 13-09-2016 IPR001610 PAC motif THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 SMART SM00086 86 129 43.0 T 13-09-2016 IPR001610 PAC motif THL1_RS10970 9fcca3c518a5d38f7257e0523dcc6074 940 SMART SM00086 365 405 37.0 T 13-09-2016 IPR001610 PAC motif THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 PANTHER PTHR32071 1 487 5.9E-152 T 13-09-2016 THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 382 391 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 SUPERFAMILY SSF46689 382 487 3.12E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 Gene3D G3DSA:3.40.50.300 166 341 9.7E-59 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 Pfam PF00158 Sigma-54 interaction domain 169 335 3.2E-66 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 SUPERFAMILY SSF52540 168 410 3.99E-68 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 Pfam PF02954 Bacterial regulatory protein, Fis family 445 483 2.5E-12 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 451 468 2.8E-9 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 468 487 2.8E-9 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 Gene3D G3DSA:1.10.8.60 342 414 2.4E-21 T 13-09-2016 THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 Gene3D G3DSA:3.30.450.20 39 125 1.8E-6 T 13-09-2016 THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 SUPERFAMILY SSF55785 32 125 6.49E-10 T 13-09-2016 IPR000014 PAS domain THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 Pfam PF08448 PAS fold 39 126 2.5E-7 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 Gene3D G3DSA:1.10.10.60 440 483 2.3E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 PANTHER PTHR32071:SF22 1 487 5.9E-152 T 13-09-2016 THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 192 205 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 255 270 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS02305 98edd8a61cc71d39f5ce751c2860c68a 487 SMART SM00382 188 333 7.3E-9 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 Pfam PF00873 AcrB/AcrD/AcrF family 7 1013 5.0E-170 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 Gene3D G3DSA:3.30.2090.10 714 800 6.2E-15 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 Gene3D G3DSA:3.30.2090.10 188 267 4.4E-13 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 PANTHER PTHR32063:SF18 3 1025 0.0 T 13-09-2016 THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 SUPERFAMILY SSF82866 796 1019 2.62E-45 T 13-09-2016 THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 PANTHER PTHR32063 3 1025 0.0 T 13-09-2016 THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 Gene3D G3DSA:3.30.70.1430 42 138 1.3E-20 T 13-09-2016 THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 SUPERFAMILY SSF82714 187 267 5.62E-12 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 SUPERFAMILY SSF82714 714 800 5.75E-15 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 SUPERFAMILY SSF82693 42 136 3.49E-19 T 13-09-2016 THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 SUPERFAMILY SSF82866 300 487 1.29E-36 T 13-09-2016 THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 Gene3D G3DSA:1.10.3850.10 804 1017 8.2E-52 T 13-09-2016 THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 Gene3D G3DSA:1.10.3850.10 276 489 2.2E-42 T 13-09-2016 THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 PRINTS PR00702 Acriflavin resistance protein family signature 439 462 2.1E-22 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 PRINTS PR00702 Acriflavin resistance protein family signature 386 410 2.1E-22 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 2.1E-22 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 2.1E-22 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 PRINTS PR00702 Acriflavin resistance protein family signature 358 379 2.1E-22 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 SUPERFAMILY SSF82693 141 184 3.66E-17 T 13-09-2016 THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 SUPERFAMILY SSF82693 270 325 3.66E-17 T 13-09-2016 THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 Gene3D G3DSA:3.30.70.1430 565 638 2.0E-4 T 13-09-2016 THL1_RS22780 4383daaf519ae8baca2ab18bc52edd9c 1038 SUPERFAMILY SSF82693 565 639 7.59E-5 T 13-09-2016 THL1_RS13295 1c24b60c32df73cfd53d80bc7d02d55e 190 Gene3D G3DSA:3.40.640.10 1 116 1.2E-31 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS13295 1c24b60c32df73cfd53d80bc7d02d55e 190 PANTHER PTHR11751 3 150 5.1E-62 T 13-09-2016 THL1_RS13295 1c24b60c32df73cfd53d80bc7d02d55e 190 SUPERFAMILY SSF53383 2 175 1.03E-40 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS13295 1c24b60c32df73cfd53d80bc7d02d55e 190 PANTHER PTHR11751:SF10 3 150 5.1E-62 T 13-09-2016 THL1_RS13295 1c24b60c32df73cfd53d80bc7d02d55e 190 Pfam PF00155 Aminotransferase class I and II 11 143 1.9E-7 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS25150 346114b8357709a48d59022f85770849 344 PIRSF PIRSF026166 1 335 5.9E-102 T 13-09-2016 IPR016833 Putative sodium bile acid cotransporter THL1_RS25150 346114b8357709a48d59022f85770849 344 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 13 321 2.5E-98 T 13-09-2016 IPR016833 Putative sodium bile acid cotransporter THL1_RS25150 346114b8357709a48d59022f85770849 344 PANTHER PTHR18640 7 319 7.3E-87 T 13-09-2016 IPR016833 Putative sodium bile acid cotransporter THL1_RS04120 0c75bddf788c0cb5677ceddff476d118 443 Gene3D G3DSA:1.20.1250.20 230 422 7.9E-32 T 13-09-2016 THL1_RS04120 0c75bddf788c0cb5677ceddff476d118 443 Gene3D G3DSA:1.20.1250.20 16 213 3.4E-41 T 13-09-2016 THL1_RS04120 0c75bddf788c0cb5677ceddff476d118 443 SUPERFAMILY SSF103473 14 421 1.57E-59 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS04120 0c75bddf788c0cb5677ceddff476d118 443 Pfam PF07690 Major Facilitator Superfamily 27 386 9.4E-43 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS04120 0c75bddf788c0cb5677ceddff476d118 443 PANTHER PTHR11662 9 428 4.0E-149 T 13-09-2016 THL1_RS04120 0c75bddf788c0cb5677ceddff476d118 443 PANTHER PTHR11662:SF141 9 428 4.0E-149 T 13-09-2016 THL1_RS04120 0c75bddf788c0cb5677ceddff476d118 443 PIRSF PIRSF002808 3 431 6.0E-79 T 13-09-2016 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 THL1_RS01380 50450e6504fad528c7e441e4b1d5b4c3 409 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 14 326 2.6E-36 T 13-09-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 THL1_RS01380 50450e6504fad528c7e441e4b1d5b4c3 409 Gene3D G3DSA:3.40.50.720 120 297 1.3E-56 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS01380 50450e6504fad528c7e441e4b1d5b4c3 409 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 200 222 - T 13-09-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site THL1_RS01380 50450e6504fad528c7e441e4b1d5b4c3 409 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 154 181 - T 13-09-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 THL1_RS01380 50450e6504fad528c7e441e4b1d5b4c3 409 PANTHER PTHR10996:SF18 1 369 1.1E-239 T 13-09-2016 IPR029015 D-3-phosphoglycerate dehydrogenase, type2 GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|UniPathway: UPA00135 THL1_RS01380 50450e6504fad528c7e441e4b1d5b4c3 409 SUPERFAMILY SSF52283 7 136 3.4E-50 T 13-09-2016 THL1_RS01380 50450e6504fad528c7e441e4b1d5b4c3 409 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 119 294 5.8E-47 T 13-09-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 THL1_RS01380 50450e6504fad528c7e441e4b1d5b4c3 409 SUPERFAMILY SSF51735 108 295 3.17E-52 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS01380 50450e6504fad528c7e441e4b1d5b4c3 409 Gene3D G3DSA:3.40.50.720 8 119 2.2E-34 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS01380 50450e6504fad528c7e441e4b1d5b4c3 409 Gene3D G3DSA:3.30.70.260 324 408 6.5E-27 T 13-09-2016 THL1_RS01380 50450e6504fad528c7e441e4b1d5b4c3 409 PANTHER PTHR10996 1 369 1.1E-239 T 13-09-2016 THL1_RS01380 50450e6504fad528c7e441e4b1d5b4c3 409 SUPERFAMILY SSF55021 334 408 2.96E-17 T 13-09-2016 THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 701 791 3.4E-10 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 SMART SM00062 40 261 2.1E-16 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 SUPERFAMILY SSF53850 41 262 3.84E-33 T 13-09-2016 THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 SMART SM00387 699 792 3.5E-12 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 Gene3D G3DSA:3.40.190.10 221 262 2.8E-14 T 13-09-2016 THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 Gene3D G3DSA:3.40.190.10 39 126 2.8E-14 T 13-09-2016 THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 328 442 4.6E-14 T 13-09-2016 IPR000014 PAS domain THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 479 574 4.3E-10 T 13-09-2016 IPR000014 PAS domain THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 Pfam PF13426 PAS domain 338 434 4.3E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 SUPERFAMILY SSF55874 668 787 3.41E-20 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 259 1.5E-22 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 SMART SM00086 526 567 0.89 T 13-09-2016 IPR001610 PAC motif THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 SMART SM00086 395 435 0.0015 T 13-09-2016 IPR001610 PAC motif THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 Gene3D G3DSA:3.40.190.10 134 216 0.001 T 13-09-2016 THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 SUPERFAMILY SSF55785 433 565 2.58E-19 T 13-09-2016 IPR000014 PAS domain THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 Gene3D G3DSA:3.30.450.20 331 443 3.8E-17 T 13-09-2016 THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 Pfam PF07730 Histidine kinase 595 661 1.8E-13 T 13-09-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 PANTHER PTHR24423 275 783 1.9E-43 T 13-09-2016 THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 SMART SM00091 447 520 8.1 T 13-09-2016 IPR000014 PAS domain THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 SMART SM00091 322 388 0.31 T 13-09-2016 IPR000014 PAS domain THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 Gene3D G3DSA:3.30.565.10 662 793 2.2E-14 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 Pfam PF08447 PAS fold 478 557 5.6E-13 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 SUPERFAMILY SSF55785 334 444 2.79E-22 T 13-09-2016 IPR000014 PAS domain THL1_RS02645 f82c41d447305390e01cbc2e9a297432 796 Gene3D G3DSA:3.30.450.20 444 565 2.5E-20 T 13-09-2016 THL1_RS20335 dec8bcdcdec57ded9fe8db3a68f82d75 381 PANTHER PTHR40659 16 113 4.1E-13 T 13-09-2016 THL1_RS20335 dec8bcdcdec57ded9fe8db3a68f82d75 381 Pfam PF03824 High-affinity nickel-transport protein 16 376 3.5E-41 T 13-09-2016 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 SUPERFAMILY SSF56719 732 796 2.51E-88 T 13-09-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 SUPERFAMILY SSF56719 396 562 2.51E-88 T 13-09-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 Gene3D G3DSA:3.40.50.670 720 788 1.9E-101 T 13-09-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 Gene3D G3DSA:3.40.50.670 406 552 1.9E-101 T 13-09-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 Pfam PF00204 DNA gyrase B 222 392 8.6E-57 T 13-09-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 SUPERFAMILY SSF54211 222 394 3.22E-57 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 Pfam PF01751 Toprim domain 421 533 2.0E-18 T 13-09-2016 IPR006171 Toprim domain THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 734 795 3.9E-30 T 13-09-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 Gene3D G3DSA:3.30.230.10 221 394 1.4E-71 T 13-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 Gene3D G3DSA:3.30.565.10 7 219 3.6E-89 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 ProSitePatterns PS00177 DNA topoisomerase II signature. 424 432 - T 13-09-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR00418 DNA topoisomerase II family signature 72 85 4.7E-71 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR00418 DNA topoisomerase II family signature 489 505 4.7E-71 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR00418 DNA topoisomerase II family signature 115 129 4.7E-71 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR00418 DNA topoisomerase II family signature 738 754 4.7E-71 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR00418 DNA topoisomerase II family signature 422 436 4.7E-71 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR00418 DNA topoisomerase II family signature 37 52 4.7E-71 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR00418 DNA topoisomerase II family signature 270 283 4.7E-71 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR00418 DNA topoisomerase II family signature 507 524 4.7E-71 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR00418 DNA topoisomerase II family signature 527 539 4.7E-71 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 SMART SM00433 37 799 1.7E-268 T 13-09-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 4 806 101.178 T 13-09-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR01159 DNA gyrase subunit B signature 759 771 1.3E-83 T 13-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR01159 DNA gyrase subunit B signature 314 330 1.3E-83 T 13-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR01159 DNA gyrase subunit B signature 182 197 1.3E-83 T 13-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR01159 DNA gyrase subunit B signature 362 376 1.3E-83 T 13-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR01159 DNA gyrase subunit B signature 775 791 1.3E-83 T 13-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR01159 DNA gyrase subunit B signature 221 243 1.3E-83 T 13-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR01159 DNA gyrase subunit B signature 197 210 1.3E-83 T 13-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR01159 DNA gyrase subunit B signature 244 262 1.3E-83 T 13-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR01159 DNA gyrase subunit B signature 376 396 1.3E-83 T 13-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR01159 DNA gyrase subunit B signature 7 17 1.3E-83 T 13-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PRINTS PR01159 DNA gyrase subunit B signature 472 481 1.3E-83 T 13-09-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PANTHER PTHR10169 4 555 0.0 T 13-09-2016 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 PANTHER PTHR10169 726 806 0.0 T 13-09-2016 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 7 806 4.6E-302 T 13-09-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 34 176 3.6E-24 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 SMART SM00387 33 177 4.0E-30 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS00020 b8936dcb2d7eb1d5e72c4f92f243c100 806 SUPERFAMILY SSF55874 7 219 1.83E-73 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS21895 7a693e190fe1e9503c2c8b55d799b1c8 269 Pfam PF13411 MerR HTH family regulatory protein 26 93 1.4E-19 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS21895 7a693e190fe1e9503c2c8b55d799b1c8 269 Gene3D G3DSA:1.10.1660.10 26 99 5.4E-19 T 13-09-2016 THL1_RS21895 7a693e190fe1e9503c2c8b55d799b1c8 269 SUPERFAMILY SSF46955 26 97 6.59E-17 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS21895 7a693e190fe1e9503c2c8b55d799b1c8 269 PANTHER PTHR30204 18 204 1.5E-32 T 13-09-2016 THL1_RS21895 7a693e190fe1e9503c2c8b55d799b1c8 269 SMART SM00422 26 94 4.1E-13 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS21895 7a693e190fe1e9503c2c8b55d799b1c8 269 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 51 2.5E-5 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS21895 7a693e190fe1e9503c2c8b55d799b1c8 269 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 27 38 2.5E-5 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS21895 7a693e190fe1e9503c2c8b55d799b1c8 269 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 61 81 2.5E-5 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS21895 7a693e190fe1e9503c2c8b55d799b1c8 269 PANTHER PTHR30204:SF13 18 204 1.5E-32 T 13-09-2016 THL1_RS14300 ea0c0b227170c381ed04194d815acc99 375 PANTHER PTHR31297 8 371 8.1E-93 T 13-09-2016 THL1_RS14300 ea0c0b227170c381ed04194d815acc99 375 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 61 352 9.0E-20 T 13-09-2016 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 THL1_RS14300 ea0c0b227170c381ed04194d815acc99 375 SUPERFAMILY SSF51445 11 372 2.54E-93 T 13-09-2016 IPR017853 Glycoside hydrolase superfamily THL1_RS14300 ea0c0b227170c381ed04194d815acc99 375 Gene3D G3DSA:3.20.20.80 13 373 1.6E-107 T 13-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 THL1_RS11560 ec021a614220af152f1c64ea4eb00a16 561 PANTHER PTHR24031 3 474 5.8E-200 T 13-09-2016 THL1_RS11560 ec021a614220af152f1c64ea4eb00a16 561 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 154 162 - T 13-09-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site THL1_RS11560 ec021a614220af152f1c64ea4eb00a16 561 PANTHER PTHR24031:SF261 514 561 5.8E-200 T 13-09-2016 THL1_RS11560 ec021a614220af152f1c64ea4eb00a16 561 Gene3D G3DSA:3.40.50.300 3 212 1.2E-77 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11560 ec021a614220af152f1c64ea4eb00a16 561 PANTHER PTHR24031 514 561 5.8E-200 T 13-09-2016 THL1_RS11560 ec021a614220af152f1c64ea4eb00a16 561 Gene3D G3DSA:3.40.50.300 213 374 1.5E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11560 ec021a614220af152f1c64ea4eb00a16 561 Hamap MF_00964 ATP-dependent RNA helicase DeaD [deaD]. 1 558 42.317 T 13-09-2016 IPR028618 ATP-dependent RNA helicase DeaD GO:0000027|GO:0004004|GO:0070417 THL1_RS11560 ec021a614220af152f1c64ea4eb00a16 561 SMART SM00487 25 223 3.0E-57 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS11560 ec021a614220af152f1c64ea4eb00a16 561 Pfam PF00271 Helicase conserved C-terminal domain 232 340 1.1E-28 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS11560 ec021a614220af152f1c64ea4eb00a16 561 Pfam PF03880 DbpA RNA binding domain 488 556 8.5E-18 T 13-09-2016 IPR005580 DbpA, RNA-binding domain THL1_RS11560 ec021a614220af152f1c64ea4eb00a16 561 SUPERFAMILY SSF52540 74 361 1.7E-70 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11560 ec021a614220af152f1c64ea4eb00a16 561 Pfam PF00270 DEAD/DEAH box helicase 31 194 2.7E-47 T 13-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THL1_RS11560 ec021a614220af152f1c64ea4eb00a16 561 SMART SM00490 259 340 3.4E-32 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS11560 ec021a614220af152f1c64ea4eb00a16 561 PANTHER PTHR24031:SF261 3 474 5.8E-200 T 13-09-2016 THL1_RS24425 93e0de5e27c65267cb6ea5167f7a9906 251 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 13-09-2016 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 THL1_RS24425 93e0de5e27c65267cb6ea5167f7a9906 251 Pfam PF00121 Triosephosphate isomerase 5 246 4.1E-86 T 13-09-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 THL1_RS24425 93e0de5e27c65267cb6ea5167f7a9906 251 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 4.8E-68 T 13-09-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 THL1_RS24425 93e0de5e27c65267cb6ea5167f7a9906 251 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 249 39.831 T 13-09-2016 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 THL1_RS24425 93e0de5e27c65267cb6ea5167f7a9906 251 PANTHER PTHR21139 1 249 3.3E-124 T 13-09-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 THL1_RS24425 93e0de5e27c65267cb6ea5167f7a9906 251 Gene3D G3DSA:3.20.20.70 1 249 1.2E-98 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS24425 93e0de5e27c65267cb6ea5167f7a9906 251 SUPERFAMILY SSF51351 1 248 1.83E-89 T 13-09-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 SUPERFAMILY SSF57783 812 867 8.5E-23 T 13-09-2016 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 SMART SM00436 138 226 1.4E-50 T 13-09-2016 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 Gene3D G3DSA:2.20.25.10 811 867 3.7E-30 T 13-09-2016 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 PANTHER PTHR11390:SF27 72 778 0.0 T 13-09-2016 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 111 124 1.7E-37 T 13-09-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 395 411 1.7E-37 T 13-09-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 319 328 1.7E-37 T 13-09-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 495 509 1.7E-37 T 13-09-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 196 214 1.7E-37 T 13-09-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 SUPERFAMILY SSF57783 746 808 1.43E-17 T 13-09-2016 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 Gene3D G3DSA:3.40.50.140 1 168 5.1E-58 T 13-09-2016 IPR006171 Toprim domain THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 SUPERFAMILY SSF56712 3 612 5.62E-202 T 13-09-2016 IPR023405 DNA topoisomerase, type IA, core domain THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 SUPERFAMILY SSF57783 701 744 6.12E-8 T 13-09-2016 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 638 1.8E-247 T 13-09-2016 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 PANTHER PTHR11390 72 778 0.0 T 13-09-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 Pfam PF01751 Toprim domain 5 147 4.6E-32 T 13-09-2016 IPR006171 Toprim domain THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 725 57.681 T 13-09-2016 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 SMART SM00437 277 532 1.6E-120 T 13-09-2016 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 314 328 - T 13-09-2016 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 601 625 6.4E-4 T 13-09-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 712 746 1.6E-9 T 13-09-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 PANTHER PTHR11390 1 37 0.0 T 13-09-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 SMART SM00493 3 137 3.6E-29 T 13-09-2016 IPR006171 Toprim domain THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 Gene3D G3DSA:1.10.460.10 169 216 1.4E-56 T 13-09-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 Gene3D G3DSA:1.10.460.10 479 583 1.4E-56 T 13-09-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 Gene3D G3DSA:3.30.65.10 707 745 1.0E-11 T 13-09-2016 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 Gene3D G3DSA:3.30.65.10 747 808 4.8E-23 T 13-09-2016 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 Gene3D G3DSA:3.30.65.10 591 627 1.3E-10 T 13-09-2016 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 Pfam PF01131 DNA topoisomerase 162 569 1.3E-127 T 13-09-2016 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 PANTHER PTHR11390:SF27 1 37 0.0 T 13-09-2016 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 Pfam PF08272 Topoisomerase I zinc-ribbon-like 826 865 5.4E-19 T 13-09-2016 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 Pfam PF08272 Topoisomerase I zinc-ribbon-like 760 795 1.7E-11 T 13-09-2016 IPR013263 DNA topoisomerase I, zinc ribbon-like, bacterial-type GO:0003677|GO:0003917|GO:0006265 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 Gene3D G3DSA:2.70.20.10 343 478 2.2E-33 T 13-09-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 THL1_RS10620 d96efc28cb7bcf0ac9b264195ddd2dbd 868 Gene3D G3DSA:2.70.20.10 218 337 4.1E-33 T 13-09-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 THL1_RS12985 30d283c2be9a46b0f85314dbfd0e3782 391 SUPERFAMILY SSF56601 34 384 1.73E-91 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS12985 30d283c2be9a46b0f85314dbfd0e3782 391 ProSitePatterns PS00336 Beta-lactamase class-C active site. 84 91 - T 13-09-2016 IPR001586 Beta-lactamase, class-C active site GO:0008800|GO:0017001|GO:0030288 KEGG: 00311+3.5.2.6 THL1_RS12985 30d283c2be9a46b0f85314dbfd0e3782 391 PANTHER PTHR22935:SF64 27 386 4.3E-62 T 13-09-2016 THL1_RS12985 30d283c2be9a46b0f85314dbfd0e3782 391 Gene3D G3DSA:3.40.710.10 35 384 9.2E-78 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS12985 30d283c2be9a46b0f85314dbfd0e3782 391 Pfam PF00144 Beta-lactamase 39 382 4.0E-70 T 13-09-2016 IPR001466 Beta-lactamase-related THL1_RS12985 30d283c2be9a46b0f85314dbfd0e3782 391 PANTHER PTHR22935 27 386 4.3E-62 T 13-09-2016 THL1_RS09035 68808cb80a7e5ff57392ab93ce1bbcc3 302 Pfam PF03186 CobD/Cbib protein 8 283 3.9E-98 T 13-09-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 THL1_RS09035 68808cb80a7e5ff57392ab93ce1bbcc3 302 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 8 268 1.1E-60 T 13-09-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 THL1_RS09035 68808cb80a7e5ff57392ab93ce1bbcc3 302 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 302 108.945 T 13-09-2016 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 UniPathway: UPA00148 THL1_RS09035 68808cb80a7e5ff57392ab93ce1bbcc3 302 PANTHER PTHR34308 1 302 1.7E-101 T 13-09-2016 THL1_RS09035 68808cb80a7e5ff57392ab93ce1bbcc3 302 PANTHER PTHR34308:SF1 1 302 1.7E-101 T 13-09-2016 THL1_RS23170 cecc18413cfadd27dfbe3be654f9802b 313 SUPERFAMILY SSF63380 93 176 4.66E-18 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS23170 cecc18413cfadd27dfbe3be654f9802b 313 Gene3D G3DSA:3.10.20.30 6 86 2.6E-22 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS23170 cecc18413cfadd27dfbe3be654f9802b 313 PANTHER PTHR19370:SF68 30 309 7.0E-46 T 13-09-2016 THL1_RS23170 cecc18413cfadd27dfbe3be654f9802b 313 SUPERFAMILY SSF52343 190 308 7.07E-20 T 13-09-2016 THL1_RS23170 cecc18413cfadd27dfbe3be654f9802b 313 PRINTS PR00410 Phenol hydroxylase reductase family signature 292 300 2.7E-7 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS23170 cecc18413cfadd27dfbe3be654f9802b 313 PRINTS PR00410 Phenol hydroxylase reductase family signature 196 215 2.7E-7 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS23170 cecc18413cfadd27dfbe3be654f9802b 313 PRINTS PR00410 Phenol hydroxylase reductase family signature 119 131 2.7E-7 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS23170 cecc18413cfadd27dfbe3be654f9802b 313 PRINTS PR00410 Phenol hydroxylase reductase family signature 135 142 2.7E-7 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS23170 cecc18413cfadd27dfbe3be654f9802b 313 SUPERFAMILY SSF54292 4 86 3.41E-22 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS23170 cecc18413cfadd27dfbe3be654f9802b 313 Pfam PF00175 Oxidoreductase NAD-binding domain 197 252 2.1E-4 T 13-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THL1_RS23170 cecc18413cfadd27dfbe3be654f9802b 313 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 76 2.1E-13 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS23170 cecc18413cfadd27dfbe3be654f9802b 313 Gene3D G3DSA:2.40.30.10 92 178 8.8E-18 T 13-09-2016 THL1_RS23170 cecc18413cfadd27dfbe3be654f9802b 313 Pfam PF00970 Oxidoreductase FAD-binding domain 106 176 2.3E-6 T 13-09-2016 IPR008333 Oxidoreductase, FAD-binding domain THL1_RS23170 cecc18413cfadd27dfbe3be654f9802b 313 PANTHER PTHR19370 30 309 7.0E-46 T 13-09-2016 THL1_RS23170 cecc18413cfadd27dfbe3be654f9802b 313 Gene3D G3DSA:3.40.50.80 192 308 9.4E-16 T 13-09-2016 THL1_RS13905 3c944a2c4880aac7959987a3ca68a795 116 Gene3D G3DSA:2.102.10.10 8 107 8.3E-22 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS13905 3c944a2c4880aac7959987a3ca68a795 116 Pfam PF00355 Rieske [2Fe-2S] domain 19 77 3.9E-12 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS13905 3c944a2c4880aac7959987a3ca68a795 116 SUPERFAMILY SSF50022 15 103 6.02E-22 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS21505 c89e108b867fab2f7db4977b0ae6f861 271 PANTHER PTHR30151 41 267 2.0E-48 T 13-09-2016 THL1_RS21505 c89e108b867fab2f7db4977b0ae6f861 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 260 8.6E-19 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS21505 c89e108b867fab2f7db4977b0ae6f861 271 Gene3D G3DSA:1.10.3720.10 69 258 3.5E-22 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS21505 c89e108b867fab2f7db4977b0ae6f861 271 SUPERFAMILY SSF161098 70 253 8.63E-29 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS21505 c89e108b867fab2f7db4977b0ae6f861 271 PANTHER PTHR30151:SF0 41 267 2.0E-48 T 13-09-2016 THL1_RS02185 6860ec00ac68d2d2627a32a7719f1317 231 Gene3D G3DSA:3.40.50.300 4 221 6.1E-77 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS02185 6860ec00ac68d2d2627a32a7719f1317 231 Pfam PF13500 AAA domain 4 211 7.1E-37 T 13-09-2016 THL1_RS02185 6860ec00ac68d2d2627a32a7719f1317 231 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 2 219 29.075 T 13-09-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380|UniPathway: UPA00078 THL1_RS02185 6860ec00ac68d2d2627a32a7719f1317 231 PANTHER PTHR21343 1 223 3.9E-104 T 13-09-2016 THL1_RS02185 6860ec00ac68d2d2627a32a7719f1317 231 PANTHER PTHR21343:SF13 1 223 3.9E-104 T 13-09-2016 THL1_RS02185 6860ec00ac68d2d2627a32a7719f1317 231 PIRSF PIRSF006755 1 229 1.1E-72 T 13-09-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380|UniPathway: UPA00078 THL1_RS02185 6860ec00ac68d2d2627a32a7719f1317 231 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 177 1.8E-44 T 13-09-2016 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380|UniPathway: UPA00078 THL1_RS02185 6860ec00ac68d2d2627a32a7719f1317 231 SUPERFAMILY SSF52540 1 216 7.97E-60 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05810 6468b5db3520a48705176fda27766943 1142 Gene3D G3DSA:3.40.50.300 1 163 4.3E-21 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05810 6468b5db3520a48705176fda27766943 1142 Pfam PF13476 AAA domain 5 203 3.8E-15 T 13-09-2016 THL1_RS05810 6468b5db3520a48705176fda27766943 1142 Gene3D G3DSA:3.40.50.300 1003 1113 2.1E-11 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05810 6468b5db3520a48705176fda27766943 1142 SUPERFAMILY SSF52540 1 182 7.1E-30 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05810 6468b5db3520a48705176fda27766943 1142 SUPERFAMILY SSF52540 993 1125 7.1E-30 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05810 6468b5db3520a48705176fda27766943 1142 PANTHER PTHR32114 734 1140 1.2E-119 T 13-09-2016 IPR027050 Nuclease SbcCD subunit C GO:0004518|GO:0006281 THL1_RS05810 6468b5db3520a48705176fda27766943 1142 PANTHER PTHR32114 2 685 1.2E-119 T 13-09-2016 IPR027050 Nuclease SbcCD subunit C GO:0004518|GO:0006281 THL1_RS05810 6468b5db3520a48705176fda27766943 1142 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1020 1095 2.3E-15 T 13-09-2016 THL1_RS05810 6468b5db3520a48705176fda27766943 1142 PANTHER PTHR32114:SF2 734 1140 1.2E-119 T 13-09-2016 THL1_RS05810 6468b5db3520a48705176fda27766943 1142 PANTHER PTHR32114:SF2 2 685 1.2E-119 T 13-09-2016 THL1_RS03645 48c6f9561b4ce03deae1a701fbe509e0 206 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 206 1.2E-78 T 13-09-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 THL1_RS03645 48c6f9561b4ce03deae1a701fbe509e0 206 PANTHER PTHR11831 1 206 2.2E-90 T 13-09-2016 IPR022801 Ribosomal protein S4/S9 THL1_RS03645 48c6f9561b4ce03deae1a701fbe509e0 206 ProSitePatterns PS00632 Ribosomal protein S4 signature. 94 118 - T 13-09-2016 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 THL1_RS03645 48c6f9561b4ce03deae1a701fbe509e0 206 Gene3D G3DSA:1.10.1050.10 1 98 1.2E-41 T 13-09-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 THL1_RS03645 48c6f9561b4ce03deae1a701fbe509e0 206 Pfam PF01479 S4 domain 97 143 1.6E-17 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS03645 48c6f9561b4ce03deae1a701fbe509e0 206 SUPERFAMILY SSF55174 3 206 9.81E-69 T 13-09-2016 THL1_RS03645 48c6f9561b4ce03deae1a701fbe509e0 206 SMART SM01390 3 95 7.3E-49 T 13-09-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 THL1_RS03645 48c6f9561b4ce03deae1a701fbe509e0 206 SMART SM00363 96 160 1.0E-17 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS03645 48c6f9561b4ce03deae1a701fbe509e0 206 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 206 34.808 T 13-09-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 THL1_RS03645 48c6f9561b4ce03deae1a701fbe509e0 206 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 95 2.5E-30 T 13-09-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 THL1_RS03645 48c6f9561b4ce03deae1a701fbe509e0 206 PANTHER PTHR11831:SF4 1 206 2.2E-90 T 13-09-2016 THL1_RS03645 48c6f9561b4ce03deae1a701fbe509e0 206 Gene3D G3DSA:3.10.290.10 99 198 2.0E-32 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS28430 dc1c2044c0bf156f00c32308c988b9de 514 PIRSF PIRSF039088 2 514 8.4E-232 T 13-09-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28430 dc1c2044c0bf156f00c32308c988b9de 514 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 2 513 49.871 T 13-09-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28430 dc1c2044c0bf156f00c32308c988b9de 514 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 367 376 - T 13-09-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28430 dc1c2044c0bf156f00c32308c988b9de 514 Gene3D G3DSA:1.20.150.20 384 511 3.3E-48 T 13-09-2016 THL1_RS28430 dc1c2044c0bf156f00c32308c988b9de 514 Gene3D G3DSA:2.40.30.20 3 94 1.1E-32 T 13-09-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28430 dc1c2044c0bf156f00c32308c988b9de 514 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 29 93 3.3E-15 T 13-09-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28430 dc1c2044c0bf156f00c32308c988b9de 514 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 4 513 7.7E-252 T 13-09-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28430 dc1c2044c0bf156f00c32308c988b9de 514 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 383 508 1.2E-44 T 13-09-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28430 dc1c2044c0bf156f00c32308c988b9de 514 SUPERFAMILY SSF50615 11 95 1.31E-28 T 13-09-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28430 dc1c2044c0bf156f00c32308c988b9de 514 SUPERFAMILY SSF52540 97 382 6.11E-94 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28430 dc1c2044c0bf156f00c32308c988b9de 514 PANTHER PTHR15184:SF3 1 497 3.6E-294 T 13-09-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28430 dc1c2044c0bf156f00c32308c988b9de 514 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 150 376 2.0E-74 T 13-09-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS28430 dc1c2044c0bf156f00c32308c988b9de 514 Gene3D G3DSA:3.40.50.300 95 383 1.1E-113 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28430 dc1c2044c0bf156f00c32308c988b9de 514 PANTHER PTHR15184 1 497 3.6E-294 T 13-09-2016 THL1_RS28430 dc1c2044c0bf156f00c32308c988b9de 514 SUPERFAMILY SSF47917 384 512 6.8E-45 T 13-09-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS03635 954d485b1f1c19578ca0817952f1ea54 118 PIRSF PIRSF002134 1 118 6.8E-43 T 13-09-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03635 954d485b1f1c19578ca0817952f1ea54 118 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 13-09-2016 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 THL1_RS03635 954d485b1f1c19578ca0817952f1ea54 118 Pfam PF00416 Ribosomal protein S13/S18 3 108 3.5E-31 T 13-09-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03635 954d485b1f1c19578ca0817952f1ea54 118 Gene3D G3DSA:1.10.8.50 1 71 5.1E-30 T 13-09-2016 THL1_RS03635 954d485b1f1c19578ca0817952f1ea54 118 PANTHER PTHR10871 1 118 6.6E-68 T 13-09-2016 THL1_RS03635 954d485b1f1c19578ca0817952f1ea54 118 Gene3D G3DSA:4.10.910.10 72 118 9.6E-27 T 13-09-2016 IPR027437 30s ribosomal protein S13, C-terminal THL1_RS03635 954d485b1f1c19578ca0817952f1ea54 118 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 1.6E-53 T 13-09-2016 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03635 954d485b1f1c19578ca0817952f1ea54 118 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 25.96 T 13-09-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03635 954d485b1f1c19578ca0817952f1ea54 118 SUPERFAMILY SSF46946 2 114 3.01E-47 T 13-09-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 SUPERFAMILY SSF82185 30 118 6.54E-23 T 13-09-2016 THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 Gene3D G3DSA:3.40.50.1460 354 465 7.1E-5 T 13-09-2016 IPR029030 Caspase-like domain THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 Gene3D G3DSA:2.20.110.10 83 188 2.5E-27 T 13-09-2016 THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 Gene3D G3DSA:2.20.110.10 189 296 1.3E-23 T 13-09-2016 THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 SMART SM00698 239 260 5.5 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 SMART SM00698 56 77 17.0 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 SMART SM00698 102 123 0.41 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 SMART SM00698 147 168 3.1 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 SMART SM00698 124 145 0.37 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 SMART SM00698 170 191 9.8 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 SMART SM00698 193 214 0.14 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 SMART SM00698 79 100 0.0079 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 SMART SM00698 33 54 2.9 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 SMART SM00698 262 283 0.61 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 SUPERFAMILY SSF52129 387 525 1.88E-5 T 13-09-2016 IPR029030 Caspase-like domain THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 Pfam PF02493 MORN repeat 195 217 3.7E-4 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 Pfam PF02493 MORN repeat 58 78 2.3E-4 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 Pfam PF02493 MORN repeat 35 56 0.025 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 Pfam PF02493 MORN repeat 149 171 0.0024 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 Pfam PF02493 MORN repeat 264 284 0.57 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 Pfam PF02493 MORN repeat 173 193 0.0095 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 Pfam PF02493 MORN repeat 126 147 3.5E-4 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 Pfam PF02493 MORN repeat 104 120 0.15 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 Pfam PF02493 MORN repeat 241 263 1.6 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 Pfam PF02493 MORN repeat 219 239 16.0 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 Pfam PF02493 MORN repeat 81 103 1.4E-5 T 13-09-2016 IPR003409 MORN motif THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 PANTHER PTHR23084 34 300 7.8E-61 T 13-09-2016 THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 Pfam PF01650 Peptidase C13 family 337 542 4.7E-40 T 13-09-2016 IPR001096 Peptidase C13, legumain GO:0006508|GO:0008233 THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 PANTHER PTHR23084:SF131 34 300 7.8E-61 T 13-09-2016 THL1_RS04165 064ebd9bb88fb530bb2a82c167df24c1 575 SUPERFAMILY SSF82185 122 232 2.68E-24 T 13-09-2016 THL1_RS17290 1654f9c6c0a1f2329d73a19bfd47a49f 335 SUPERFAMILY SSF52540 28 293 4.61E-36 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17290 1654f9c6c0a1f2329d73a19bfd47a49f 335 PANTHER PTHR30258 27 321 4.9E-89 T 13-09-2016 THL1_RS17290 1654f9c6c0a1f2329d73a19bfd47a49f 335 Gene3D G3DSA:3.40.50.300 131 318 4.3E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17290 1654f9c6c0a1f2329d73a19bfd47a49f 335 Pfam PF00437 Type II/IV secretion system protein 30 295 1.2E-78 T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS17290 1654f9c6c0a1f2329d73a19bfd47a49f 335 TIGRFAM TIGR02782 TrbB_P: P-type conjugative transfer ATPase TrbB 18 317 6.9E-125 T 13-09-2016 IPR014149 Conjugative transfer, TrbB GO:0000746|GO:0005737 THL1_RS17290 1654f9c6c0a1f2329d73a19bfd47a49f 335 Gene3D G3DSA:3.30.450.90 31 121 6.4E-12 T 13-09-2016 THL1_RS17290 1654f9c6c0a1f2329d73a19bfd47a49f 335 PANTHER PTHR30258:SF12 27 321 4.9E-89 T 13-09-2016 THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 159 172 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 348 357 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 Gene3D G3DSA:1.10.8.60 308 379 1.4E-24 T 13-09-2016 THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 Gene3D G3DSA:3.40.50.2300 3 125 4.7E-35 T 13-09-2016 THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 Pfam PF00072 Response regulator receiver domain 7 115 1.1E-28 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 SUPERFAMILY SSF52172 1 178 1.42E-42 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 SUPERFAMILY SSF46689 349 445 8.96E-18 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 SMART SM00448 4 115 1.4E-33 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 PANTHER PTHR32071:SF28 1 445 4.0E-279 T 13-09-2016 THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 Gene3D G3DSA:1.10.10.60 397 441 2.4E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 Pfam PF02954 Bacterial regulatory protein, Fis family 402 442 2.3E-16 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 408 425 1.5E-12 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 425 445 1.5E-12 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 Gene3D G3DSA:3.40.50.300 134 307 6.1E-60 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 SMART SM00382 155 298 1.0E-7 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 SUPERFAMILY SSF52540 135 377 5.98E-67 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 Pfam PF00158 Sigma-54 interaction domain 136 301 1.4E-66 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 221 236 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS04950 d81b72914a2bea73a73adf3ae8f3d2dc 445 PANTHER PTHR32071 1 445 4.0E-279 T 13-09-2016 THL1_RS21545 788fabdf69940519135a372c7b194cbc 361 Gene3D G3DSA:3.40.50.300 19 226 6.2E-57 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21545 788fabdf69940519135a372c7b194cbc 361 SUPERFAMILY SSF50331 240 359 1.04E-16 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS21545 788fabdf69940519135a372c7b194cbc 361 TIGRFAM TIGR02142 modC_ABC: molybdate ABC transporter, ATP-binding protein 4 359 3.6E-139 T 13-09-2016 IPR011868 Molybdate ABC transporter, ATP-binding protein GO:0005524|GO:0015098|GO:0015689|GO:0016020 THL1_RS21545 788fabdf69940519135a372c7b194cbc 361 SUPERFAMILY SSF52540 11 225 3.1E-62 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21545 788fabdf69940519135a372c7b194cbc 361 PANTHER PTHR24220:SF284 2 231 1.2E-102 T 13-09-2016 THL1_RS21545 788fabdf69940519135a372c7b194cbc 361 SMART SM00382 25 212 5.4E-15 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS21545 788fabdf69940519135a372c7b194cbc 361 PANTHER PTHR24220 2 231 1.2E-102 T 13-09-2016 THL1_RS21545 788fabdf69940519135a372c7b194cbc 361 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS21545 788fabdf69940519135a372c7b194cbc 361 Gene3D G3DSA:2.40.50.100 284 357 5.0E-15 T 13-09-2016 THL1_RS21545 788fabdf69940519135a372c7b194cbc 361 Pfam PF00005 ABC transporter 21 162 1.5E-27 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS21545 788fabdf69940519135a372c7b194cbc 361 Pfam PF03459 TOBE domain 297 359 6.1E-13 T 13-09-2016 IPR005116 Transport-associated OB, type 1 THL1_RS07295 59b0db1587f49ff7839a0cfbfddc797d 161 SUPERFAMILY SSF50475 3 155 2.89E-43 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS07295 59b0db1587f49ff7839a0cfbfddc797d 161 PANTHER PTHR30466 2 160 8.5E-34 T 13-09-2016 THL1_RS07295 59b0db1587f49ff7839a0cfbfddc797d 161 Pfam PF01613 Flavin reductase like domain 11 154 5.0E-34 T 13-09-2016 IPR002563 Flavin reductase like domain GO:0010181 THL1_RS07295 59b0db1587f49ff7839a0cfbfddc797d 161 SMART SM00903 11 156 6.6E-50 T 13-09-2016 IPR002563 Flavin reductase like domain GO:0010181 THL1_RS07295 59b0db1587f49ff7839a0cfbfddc797d 161 Gene3D G3DSA:2.30.110.10 3 153 1.9E-47 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS03540 926fbe05aa88e94961c49b256de09f2e 273 PIRSF PIRSF002158 12 273 1.0E-100 T 13-09-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03540 926fbe05aa88e94961c49b256de09f2e 273 SMART SM01383 42 118 3.3E-45 T 13-09-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03540 926fbe05aa88e94961c49b256de09f2e 273 Gene3D G3DSA:2.30.30.30 119 195 3.3E-31 T 13-09-2016 IPR014722 Ribosomal protein L2 domain 2 THL1_RS03540 926fbe05aa88e94961c49b256de09f2e 273 SMART SM01382 124 252 5.6E-92 T 13-09-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 THL1_RS03540 926fbe05aa88e94961c49b256de09f2e 273 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 47.13 T 13-09-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 THL1_RS03540 926fbe05aa88e94961c49b256de09f2e 273 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 1.4E-33 T 13-09-2016 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03540 926fbe05aa88e94961c49b256de09f2e 273 Gene3D G3DSA:4.10.950.10 196 272 4.5E-35 T 13-09-2016 IPR014726 Ribosomal protein L2, domain 3 THL1_RS03540 926fbe05aa88e94961c49b256de09f2e 273 PANTHER PTHR13691 1 273 9.0E-143 T 13-09-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03540 926fbe05aa88e94961c49b256de09f2e 273 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 250 7.8E-56 T 13-09-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 THL1_RS03540 926fbe05aa88e94961c49b256de09f2e 273 SUPERFAMILY SSF50104 127 272 1.87E-60 T 13-09-2016 IPR008991 Translation protein SH3-like domain THL1_RS03540 926fbe05aa88e94961c49b256de09f2e 273 SUPERFAMILY SSF50249 2 125 7.2E-48 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS03540 926fbe05aa88e94961c49b256de09f2e 273 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 13-09-2016 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 THL1_RS03540 926fbe05aa88e94961c49b256de09f2e 273 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 273 1.6E-129 T 13-09-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 THL1_RS03540 926fbe05aa88e94961c49b256de09f2e 273 Gene3D G3DSA:2.40.50.140 1 114 7.4E-50 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS17055 eb520e657ca790350557504071cdc08b 167 Gene3D G3DSA:3.40.630.30 7 159 2.9E-24 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS17055 eb520e657ca790350557504071cdc08b 167 PANTHER PTHR23091 6 158 7.1E-17 T 13-09-2016 THL1_RS17055 eb520e657ca790350557504071cdc08b 167 Pfam PF00583 Acetyltransferase (GNAT) family 72 152 4.4E-11 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS17055 eb520e657ca790350557504071cdc08b 167 SUPERFAMILY SSF55729 6 158 5.65E-26 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS18985 91d0f90fe35dcf8eef119ff0cbde7c21 430 SUPERFAMILY SSF103473 15 416 3.27E-25 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS18985 91d0f90fe35dcf8eef119ff0cbde7c21 430 Gene3D G3DSA:1.20.1250.20 19 190 2.0E-9 T 13-09-2016 THL1_RS18985 91d0f90fe35dcf8eef119ff0cbde7c21 430 PANTHER PTHR31187 3 415 1.2E-63 T 13-09-2016 IPR004667 ADP/ATP carrier protein GO:0005471|GO:0005524|GO:0006810|GO:0016021 THL1_RS18985 91d0f90fe35dcf8eef119ff0cbde7c21 430 Pfam PF07690 Major Facilitator Superfamily 38 333 2.7E-13 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 SUPERFAMILY SSF51905 1 362 5.62E-61 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 2.3E-30 T 13-09-2016 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.3E-30 T 13-09-2016 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 2.3E-30 T 13-09-2016 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 2.3E-30 T 13-09-2016 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 2.3E-30 T 13-09-2016 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 317 1.6E-68 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 1.0E-68 T 13-09-2016 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 399 414 1.0E-68 T 13-09-2016 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 1.0E-68 T 13-09-2016 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 421 441 1.0E-68 T 13-09-2016 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 1.0E-68 T 13-09-2016 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.0E-68 T 13-09-2016 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 1.0E-68 T 13-09-2016 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 1.0E-68 T 13-09-2016 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 355 1.0E-68 T 13-09-2016 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 PANTHER PTHR22912 1 450 1.7E-214 T 13-09-2016 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 TIGRFAM TIGR01424 gluta_reduc_2: glutathione-disulfide reductase 3 447 2.7E-183 T 13-09-2016 IPR006324 Glutathione-disulphide reductase GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 SUPERFAMILY SSF55424 335 447 3.09E-37 T 13-09-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 Gene3D G3DSA:3.50.50.60 138 325 8.0E-55 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 Gene3D G3DSA:3.50.50.60 3 137 8.8E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 PANTHER PTHR22912:SF106 1 450 1.7E-214 T 13-09-2016 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 13-09-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 Gene3D G3DSA:3.30.390.30 337 450 9.1E-44 T 13-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 338 446 2.8E-36 T 13-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THL1_RS12540 3c4922dcedd62b21ac0141978c3ad9a3 452 PIRSF PIRSF000350 1 442 9.5E-87 T 13-09-2016 THL1_RS15425 0c35914f27d97ad4ae9694f9de8edf7d 269 SUPERFAMILY SSF51735 28 268 1.9E-79 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS15425 0c35914f27d97ad4ae9694f9de8edf7d 269 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 164 192 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS15425 0c35914f27d97ad4ae9694f9de8edf7d 269 PANTHER PTHR24322 177 209 4.2E-53 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15425 0c35914f27d97ad4ae9694f9de8edf7d 269 PANTHER PTHR24322 32 161 4.2E-53 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15425 0c35914f27d97ad4ae9694f9de8edf7d 269 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 34 268 2.0E-62 T 13-09-2016 THL1_RS15425 0c35914f27d97ad4ae9694f9de8edf7d 269 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 28 208 6.2E-5 T 13-09-2016 THL1_RS15425 0c35914f27d97ad4ae9694f9de8edf7d 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 177 196 1.5E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15425 0c35914f27d97ad4ae9694f9de8edf7d 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 104 115 1.5E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15425 0c35914f27d97ad4ae9694f9de8edf7d 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 165 1.5E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15425 0c35914f27d97ad4ae9694f9de8edf7d 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 29 46 3.3E-39 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15425 0c35914f27d97ad4ae9694f9de8edf7d 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 232 252 3.3E-39 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15425 0c35914f27d97ad4ae9694f9de8edf7d 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 215 3.3E-39 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15425 0c35914f27d97ad4ae9694f9de8edf7d 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 167 3.3E-39 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15425 0c35914f27d97ad4ae9694f9de8edf7d 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 196 3.3E-39 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15425 0c35914f27d97ad4ae9694f9de8edf7d 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 104 115 3.3E-39 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15425 0c35914f27d97ad4ae9694f9de8edf7d 269 Gene3D G3DSA:3.40.50.720 19 268 2.4E-82 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS04315 45d9eed04e0bcd1f57ab63e93fdd1d09 154 SUPERFAMILY SSF55486 4 148 1.49E-47 T 13-09-2016 THL1_RS04315 45d9eed04e0bcd1f57ab63e93fdd1d09 154 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 37 143 1.9E-36 T 13-09-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 THL1_RS04315 45d9eed04e0bcd1f57ab63e93fdd1d09 154 Gene3D G3DSA:3.40.390.30 13 150 5.8E-52 T 13-09-2016 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 THL1_RS04315 45d9eed04e0bcd1f57ab63e93fdd1d09 154 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 112 122 - T 13-09-2016 IPR020549 Endoribonuclease YbeY, conserved site THL1_RS04315 45d9eed04e0bcd1f57ab63e93fdd1d09 154 PANTHER PTHR22881 1 149 7.3E-59 T 13-09-2016 THL1_RS04315 45d9eed04e0bcd1f57ab63e93fdd1d09 154 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 3 146 24.43 T 13-09-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 THL1_RS04315 45d9eed04e0bcd1f57ab63e93fdd1d09 154 Pfam PF02130 Uncharacterized protein family UPF0054 19 142 3.6E-38 T 13-09-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 THL1_RS25990 37e031a639b3dbac467f46ea98c3dec6 205 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 12 195 1.5E-54 T 13-09-2016 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 THL1_RS25990 37e031a639b3dbac467f46ea98c3dec6 205 ProSitePatterns PS00893 Nudix box signature. 93 114 - T 13-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THL1_RS25990 37e031a639b3dbac467f46ea98c3dec6 205 Pfam PF00293 NUDIX domain 52 176 1.3E-14 T 13-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 THL1_RS25990 37e031a639b3dbac467f46ea98c3dec6 205 PANTHER PTHR11839:SF5 12 204 4.0E-94 T 13-09-2016 THL1_RS25990 37e031a639b3dbac467f46ea98c3dec6 205 Gene3D G3DSA:3.90.79.10 12 197 1.7E-57 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS25990 37e031a639b3dbac467f46ea98c3dec6 205 PANTHER PTHR11839 12 204 4.0E-94 T 13-09-2016 THL1_RS25990 37e031a639b3dbac467f46ea98c3dec6 205 SUPERFAMILY SSF55811 17 197 2.44E-47 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS26505 763af5632795bdd8d868a696fbda95fc 267 TIGRFAM TIGR02017 hutG_amidohyd: N-formylglutamate deformylase 4 262 9.0E-122 T 13-09-2016 IPR010247 N-formylglutamate deformylase THL1_RS26505 763af5632795bdd8d868a696fbda95fc 267 Pfam PF05013 N-formylglutamate amidohydrolase 12 230 7.8E-69 T 13-09-2016 IPR007709 N-formylglutamate amidohydrolase THL1_RS26505 763af5632795bdd8d868a696fbda95fc 267 Gene3D G3DSA:3.40.630.40 4 263 2.9E-91 T 13-09-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 THL1_RS26505 763af5632795bdd8d868a696fbda95fc 267 SUPERFAMILY SSF53187 5 263 1.28E-81 T 13-09-2016 THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 PANTHER PTHR24423:SF485 14 43 1.2E-96 T 13-09-2016 THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 PANTHER PTHR24423 14 43 1.2E-96 T 13-09-2016 THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 PRINTS PR00344 Bacterial sensor protein C-terminal signature 541 559 8.3E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 PRINTS PR00344 Bacterial sensor protein C-terminal signature 564 577 8.3E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 PRINTS PR00344 Bacterial sensor protein C-terminal signature 528 538 8.3E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 524 8.3E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 471 579 1.1E-20 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 PANTHER PTHR24423:SF485 186 294 1.2E-96 T 13-09-2016 THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 PANTHER PTHR24423 320 336 1.2E-96 T 13-09-2016 THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 PANTHER PTHR24423 357 578 1.2E-96 T 13-09-2016 THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 PANTHER PTHR24423:SF485 320 336 1.2E-96 T 13-09-2016 THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 PANTHER PTHR24423:SF485 357 578 1.2E-96 T 13-09-2016 THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 PANTHER PTHR24423 186 294 1.2E-96 T 13-09-2016 THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 SMART SM00387 471 580 6.2E-32 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 Gene3D G3DSA:3.30.565.10 435 584 5.5E-37 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 SMART SM00388 361 429 2.7E-7 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 Pfam PF00512 His Kinase A (phospho-acceptor) domain 361 426 9.2E-7 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 SUPERFAMILY SSF103190 107 191 1.02E-11 T 13-09-2016 IPR029151 Periplasmic sensor domain-like THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 PIRSF PIRSF036431 1 586 1.2E-179 T 13-09-2016 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 Gene3D G3DSA:1.10.287.130 358 425 7.4E-5 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 Gene3D G3DSA:3.30.450.20 100 181 2.4E-5 T 13-09-2016 THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 SUPERFAMILY SSF55874 433 578 1.44E-37 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS28345 a93b933abf5fa473fe576f4725f2848b 586 SUPERFAMILY SSF47384 357 429 2.16E-9 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS03605 cad808bfaf137d4791c2819c0eae273f 116 SUPERFAMILY SSF53137 4 114 1.87E-51 T 13-09-2016 THL1_RS03605 cad808bfaf137d4791c2819c0eae273f 116 Gene3D G3DSA:3.30.420.100 24 116 1.1E-38 T 13-09-2016 THL1_RS03605 cad808bfaf137d4791c2819c0eae273f 116 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 4 116 2.0E-41 T 13-09-2016 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03605 cad808bfaf137d4791c2819c0eae273f 116 PANTHER PTHR12899 4 116 1.1E-41 T 13-09-2016 THL1_RS03605 cad808bfaf137d4791c2819c0eae273f 116 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 4 116 2.2E-41 T 13-09-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03605 cad808bfaf137d4791c2819c0eae273f 116 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 3 116 27.08 T 13-09-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS13595 708ccbb7c66c58f2ccb1d50a0a2064ae 299 PANTHER PTHR30537 1 296 1.2E-90 T 13-09-2016 THL1_RS13595 708ccbb7c66c58f2ccb1d50a0a2064ae 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 2.2E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS13595 708ccbb7c66c58f2ccb1d50a0a2064ae 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 2.2E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS13595 708ccbb7c66c58f2ccb1d50a0a2064ae 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 2.2E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS13595 708ccbb7c66c58f2ccb1d50a0a2064ae 299 Pfam PF03466 LysR substrate binding domain 91 288 9.4E-29 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS13595 708ccbb7c66c58f2ccb1d50a0a2064ae 299 Gene3D G3DSA:3.40.190.10 97 196 6.4E-21 T 13-09-2016 THL1_RS13595 708ccbb7c66c58f2ccb1d50a0a2064ae 299 SUPERFAMILY SSF46785 5 87 2.94E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13595 708ccbb7c66c58f2ccb1d50a0a2064ae 299 PANTHER PTHR30537:SF16 1 296 1.2E-90 T 13-09-2016 THL1_RS13595 708ccbb7c66c58f2ccb1d50a0a2064ae 299 Gene3D G3DSA:1.10.10.10 8 91 4.1E-26 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13595 708ccbb7c66c58f2ccb1d50a0a2064ae 299 SUPERFAMILY SSF53850 95 292 2.71E-29 T 13-09-2016 THL1_RS13595 708ccbb7c66c58f2ccb1d50a0a2064ae 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 1.5E-19 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS16935 28a2e221e5b29335a905907a7bd001dc 312 SUPERFAMILY SSF53850 90 300 9.59E-41 T 13-09-2016 THL1_RS16935 28a2e221e5b29335a905907a7bd001dc 312 Gene3D G3DSA:1.10.10.10 3 82 4.7E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS16935 28a2e221e5b29335a905907a7bd001dc 312 PANTHER PTHR30537 1 312 2.3E-99 T 13-09-2016 THL1_RS16935 28a2e221e5b29335a905907a7bd001dc 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.3E-21 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS16935 28a2e221e5b29335a905907a7bd001dc 312 PANTHER PTHR30537:SF5 1 312 2.3E-99 T 13-09-2016 THL1_RS16935 28a2e221e5b29335a905907a7bd001dc 312 SUPERFAMILY SSF46785 4 111 6.01E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS16935 28a2e221e5b29335a905907a7bd001dc 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.8E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS16935 28a2e221e5b29335a905907a7bd001dc 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.8E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS16935 28a2e221e5b29335a905907a7bd001dc 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.8E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS16935 28a2e221e5b29335a905907a7bd001dc 312 Gene3D G3DSA:3.40.190.10 92 176 8.1E-21 T 13-09-2016 THL1_RS16935 28a2e221e5b29335a905907a7bd001dc 312 Pfam PF03466 LysR substrate binding domain 88 295 2.8E-40 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS16935 28a2e221e5b29335a905907a7bd001dc 312 Gene3D G3DSA:3.40.190.10 177 263 2.9E-19 T 13-09-2016 THL1_RS22380 d4780ea39b128b4304f3b9e7e2601ec0 116 PANTHER PTHR34290 1 116 1.7E-12 T 13-09-2016 THL1_RS22380 d4780ea39b128b4304f3b9e7e2601ec0 116 Pfam PF04134 Protein of unknown function, DUF393 4 115 6.1E-18 T 13-09-2016 IPR007263 Protein of unknown function DUF393 THL1_RS08910 0e21ac6bb5117023357cd98cc774cf90 238 SUPERFAMILY SSF56214 120 213 1.44E-17 T 13-09-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 THL1_RS08910 0e21ac6bb5117023357cd98cc774cf90 238 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 122 207 4.1E-13 T 13-09-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 THL1_RS08910 0e21ac6bb5117023357cd98cc774cf90 238 PRINTS PR01399 Enterobactin synthetase component D signature 88 106 1.1E-18 T 13-09-2016 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UniPathway: UPA00017 THL1_RS08910 0e21ac6bb5117023357cd98cc774cf90 238 PRINTS PR01399 Enterobactin synthetase component D signature 58 78 1.1E-18 T 13-09-2016 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UniPathway: UPA00017 THL1_RS08910 0e21ac6bb5117023357cd98cc774cf90 238 PRINTS PR01399 Enterobactin synthetase component D signature 166 182 1.1E-18 T 13-09-2016 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 UniPathway: UPA00017 THL1_RS08910 0e21ac6bb5117023357cd98cc774cf90 238 PANTHER PTHR38096 15 238 5.9E-60 T 13-09-2016 THL1_RS08910 0e21ac6bb5117023357cd98cc774cf90 238 Gene3D G3DSA:3.90.470.20 121 206 3.7E-11 T 13-09-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 THL1_RS01770 0e516889fc639977a879cc747eb3fb7f 367 SUPERFAMILY SSF46689 224 274 2.42E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01770 0e516889fc639977a879cc747eb3fb7f 367 Pfam PF12833 Helix-turn-helix domain 247 323 4.1E-22 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS01770 0e516889fc639977a879cc747eb3fb7f 367 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 277 319 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS01770 0e516889fc639977a879cc747eb3fb7f 367 PANTHER PTHR11019 16 39 3.1E-77 T 13-09-2016 THL1_RS01770 0e516889fc639977a879cc747eb3fb7f 367 Gene3D G3DSA:3.40.50.880 17 230 4.5E-44 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS01770 0e516889fc639977a879cc747eb3fb7f 367 SMART SM00342 240 323 5.4E-28 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS01770 0e516889fc639977a879cc747eb3fb7f 367 SUPERFAMILY SSF52317 15 205 1.4E-46 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS01770 0e516889fc639977a879cc747eb3fb7f 367 SUPERFAMILY SSF46689 276 326 2.73E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01770 0e516889fc639977a879cc747eb3fb7f 367 PANTHER PTHR11019 65 331 3.1E-77 T 13-09-2016 THL1_RS01770 0e516889fc639977a879cc747eb3fb7f 367 Pfam PF01965 DJ-1/PfpI family 24 184 1.8E-16 T 13-09-2016 IPR002818 DJ-1/PfpI THL1_RS01770 0e516889fc639977a879cc747eb3fb7f 367 Gene3D G3DSA:1.10.10.60 231 276 2.0E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01770 0e516889fc639977a879cc747eb3fb7f 367 PANTHER PTHR11019:SF90 65 331 3.1E-77 T 13-09-2016 THL1_RS01770 0e516889fc639977a879cc747eb3fb7f 367 PANTHER PTHR11019:SF90 16 39 3.1E-77 T 13-09-2016 THL1_RS01770 0e516889fc639977a879cc747eb3fb7f 367 Gene3D G3DSA:1.10.10.60 277 326 3.1E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS04135 1b3a31972ae36ab7e0c8ca8484cabb78 450 SUPERFAMILY SSF53623 94 309 3.4E-52 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS04135 1b3a31972ae36ab7e0c8ca8484cabb78 450 SUPERFAMILY SSF53244 311 448 3.92E-36 T 13-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 THL1_RS04135 1b3a31972ae36ab7e0c8ca8484cabb78 450 Gene3D G3DSA:3.40.1190.10 92 312 7.8E-88 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS04135 1b3a31972ae36ab7e0c8ca8484cabb78 450 Gene3D G3DSA:3.90.190.20 313 449 1.9E-32 T 13-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 THL1_RS04135 1b3a31972ae36ab7e0c8ca8484cabb78 450 SUPERFAMILY SSF51984 1 90 7.59E-24 T 13-09-2016 THL1_RS04135 1b3a31972ae36ab7e0c8ca8484cabb78 450 Gene3D G3DSA:3.40.50.720 1 90 8.0E-41 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS04135 1b3a31972ae36ab7e0c8ca8484cabb78 450 Pfam PF02875 Mur ligase family, glutamate ligase domain 311 359 1.1E-9 T 13-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 THL1_RS04135 1b3a31972ae36ab7e0c8ca8484cabb78 450 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 449 60.979 T 13-09-2016 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 UniPathway: UPA00544 THL1_RS04135 1b3a31972ae36ab7e0c8ca8484cabb78 450 Pfam PF08245 Mur ligase middle domain 108 291 1.5E-21 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS04135 1b3a31972ae36ab7e0c8ca8484cabb78 450 Pfam PF01225 Mur ligase family, catalytic domain 2 100 8.6E-20 T 13-09-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS04135 1b3a31972ae36ab7e0c8ca8484cabb78 450 PANTHER PTHR23135:SF17 1 439 1.1E-278 T 13-09-2016 THL1_RS04135 1b3a31972ae36ab7e0c8ca8484cabb78 450 PANTHER PTHR23135 1 439 1.1E-278 T 13-09-2016 THL1_RS04135 1b3a31972ae36ab7e0c8ca8484cabb78 450 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 448 4.4E-219 T 13-09-2016 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 UniPathway: UPA00544 THL1_RS03310 b0b0e66d06aa63b5896b0ba8fe22c9f1 349 Gene3D G3DSA:3.40.1030.10 76 340 2.3E-102 T 13-09-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 THL1_RS03310 b0b0e66d06aa63b5896b0ba8fe22c9f1 349 PANTHER PTHR11922:SF5 1 340 1.1E-108 T 13-09-2016 THL1_RS03310 b0b0e66d06aa63b5896b0ba8fe22c9f1 349 PANTHER PTHR11922 1 340 1.1E-108 T 13-09-2016 THL1_RS03310 b0b0e66d06aa63b5896b0ba8fe22c9f1 349 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 64 7.9E-20 T 13-09-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain THL1_RS03310 b0b0e66d06aa63b5896b0ba8fe22c9f1 349 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 5 339 39.28 T 13-09-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 THL1_RS03310 b0b0e66d06aa63b5896b0ba8fe22c9f1 349 Pfam PF00591 Glycosyl transferase family, a/b domain 76 329 1.7E-100 T 13-09-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 THL1_RS03310 b0b0e66d06aa63b5896b0ba8fe22c9f1 349 SUPERFAMILY SSF47648 1 69 8.63E-22 T 13-09-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain THL1_RS03310 b0b0e66d06aa63b5896b0ba8fe22c9f1 349 Gene3D G3DSA:1.20.970.10 4 70 1.9E-26 T 13-09-2016 THL1_RS03310 b0b0e66d06aa63b5896b0ba8fe22c9f1 349 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 7 338 9.2E-125 T 13-09-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 THL1_RS03310 b0b0e66d06aa63b5896b0ba8fe22c9f1 349 SUPERFAMILY SSF52418 75 340 3.92E-90 T 13-09-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 THL1_RS05395 aee6685c9e7feeb8dde28976bde4289b 269 Pfam PF00005 ABC transporter 25 172 4.2E-30 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS05395 aee6685c9e7feeb8dde28976bde4289b 269 PANTHER PTHR24220:SF368 10 266 9.4E-174 T 13-09-2016 THL1_RS05395 aee6685c9e7feeb8dde28976bde4289b 269 SUPERFAMILY SSF52540 8 236 4.14E-63 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05395 aee6685c9e7feeb8dde28976bde4289b 269 PANTHER PTHR24220 10 266 9.4E-174 T 13-09-2016 THL1_RS05395 aee6685c9e7feeb8dde28976bde4289b 269 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS05395 aee6685c9e7feeb8dde28976bde4289b 269 Gene3D G3DSA:3.40.50.300 5 243 1.4E-67 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05395 aee6685c9e7feeb8dde28976bde4289b 269 SMART SM00382 33 222 5.0E-14 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS19695 aa5edfb2f415b9715be9f0c86f788cf8 247 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 121 2.3E-32 T 13-09-2016 IPR020013 Fagellar hook-basal body protein, FlgE/F/G THL1_RS19695 aa5edfb2f415b9715be9f0c86f788cf8 247 PANTHER PTHR30435 1 247 1.7E-104 T 13-09-2016 THL1_RS19695 aa5edfb2f415b9715be9f0c86f788cf8 247 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 5 224 4.8E-55 T 13-09-2016 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 THL1_RS19695 aa5edfb2f415b9715be9f0c86f788cf8 247 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 171 241 7.4E-20 T 13-09-2016 IPR010930 Flagellar basal-body/hook protein, C-terminal domain THL1_RS19695 aa5edfb2f415b9715be9f0c86f788cf8 247 PANTHER PTHR30435:SF18 1 247 1.7E-104 T 13-09-2016 THL1_RS19695 aa5edfb2f415b9715be9f0c86f788cf8 247 SUPERFAMILY SSF117143 77 179 1.03E-14 T 13-09-2016 THL1_RS19695 aa5edfb2f415b9715be9f0c86f788cf8 247 Pfam PF00460 Flagella basal body rod protein 5 35 2.4E-7 T 13-09-2016 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 THL1_RS07955 54939b69f647e4df25f93e770b4ce7c4 475 PANTHER PTHR24423:SF505 232 471 1.3E-52 T 13-09-2016 THL1_RS07955 54939b69f647e4df25f93e770b4ce7c4 475 Pfam PF00512 His Kinase A (phospho-acceptor) domain 256 319 1.4E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS07955 54939b69f647e4df25f93e770b4ce7c4 475 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 470 9.2E-21 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS07955 54939b69f647e4df25f93e770b4ce7c4 475 SUPERFAMILY SSF47384 245 319 1.04E-8 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS07955 54939b69f647e4df25f93e770b4ce7c4 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 417 9.4E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS07955 54939b69f647e4df25f93e770b4ce7c4 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 469 9.4E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS07955 54939b69f647e4df25f93e770b4ce7c4 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 450 9.4E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS07955 54939b69f647e4df25f93e770b4ce7c4 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 431 9.4E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS07955 54939b69f647e4df25f93e770b4ce7c4 475 SMART SM00388 255 324 1.4E-7 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS07955 54939b69f647e4df25f93e770b4ce7c4 475 Gene3D G3DSA:3.30.565.10 327 471 7.3E-34 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS07955 54939b69f647e4df25f93e770b4ce7c4 475 Gene3D G3DSA:1.10.287.130 253 314 3.2E-5 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS07955 54939b69f647e4df25f93e770b4ce7c4 475 SUPERFAMILY SSF55874 325 470 1.57E-34 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS07955 54939b69f647e4df25f93e770b4ce7c4 475 SMART SM00387 367 472 1.6E-30 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS07955 54939b69f647e4df25f93e770b4ce7c4 475 PANTHER PTHR24423 232 471 1.3E-52 T 13-09-2016 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 PANTHER PTHR11670 726 867 0.0 T 13-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 PANTHER PTHR11670:SF43 1 683 0.0 T 13-09-2016 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 PRINTS PR00415 Aconitase family signature 138 151 2.3E-28 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 PRINTS PR00415 Aconitase family signature 281 294 2.3E-28 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 PRINTS PR00415 Aconitase family signature 409 420 2.3E-28 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 PRINTS PR00415 Aconitase family signature 267 280 2.3E-28 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 PRINTS PR00415 Aconitase family signature 360 374 2.3E-28 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 PRINTS PR00415 Aconitase family signature 471 484 2.3E-28 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 PRINTS PR00415 Aconitase family signature 205 220 2.3E-28 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 PRINTS PR00415 Aconitase family signature 162 170 2.3E-28 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 PRINTS PR00415 Aconitase family signature 191 204 2.3E-28 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 SUPERFAMILY SSF53732 21 594 3.4E-185 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 TIGRFAM TIGR02333 2met_isocit_dHY: 2-methylisocitrate dehydratase, Fe/S-dependent 2 865 0.0 T 13-09-2016 IPR012708 2-methylisocitrate dehydratase AcnD, Fe/S-dependent GO:0019679 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|UniPathway: UPA00946 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 Gene3D G3DSA:3.20.19.10 612 863 1.1E-64 T 13-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 Gene3D G3DSA:3.40.1060.10 238 355 2.3E-35 T 13-09-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 SUPERFAMILY SSF52016 605 863 3.53E-67 T 13-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 Pfam PF00330 Aconitase family (aconitate hydratase) 70 540 3.1E-150 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 PANTHER PTHR11670:SF43 726 867 0.0 T 13-09-2016 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 PANTHER PTHR11670 1 683 0.0 T 13-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 Gene3D G3DSA:3.30.499.10 357 553 5.7E-55 T 13-09-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 30 862 3.2E-285 T 13-09-2016 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 Gene3D G3DSA:3.30.499.10 24 236 4.3E-60 T 13-09-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18175 a45d49ffdd745a6c46cba31a077f73d3 873 Pfam PF00694 Aconitase C-terminal domain 663 793 4.8E-30 T 13-09-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS20895 346a0d6db73630ae1e880c76e5644e95 547 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 149 261 8.0E-24 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS20895 346a0d6db73630ae1e880c76e5644e95 547 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 389 537 1.3E-36 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS20895 346a0d6db73630ae1e880c76e5644e95 547 Gene3D G3DSA:2.40.110.10 265 376 2.2E-23 T 13-09-2016 THL1_RS20895 346a0d6db73630ae1e880c76e5644e95 547 Gene3D G3DSA:1.10.540.10 144 261 1.2E-23 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS20895 346a0d6db73630ae1e880c76e5644e95 547 SUPERFAMILY SSF56645 142 401 1.96E-53 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS20895 346a0d6db73630ae1e880c76e5644e95 547 Gene3D G3DSA:1.20.140.10 377 539 1.0E-46 T 13-09-2016 THL1_RS20895 346a0d6db73630ae1e880c76e5644e95 547 PANTHER PTHR10909 134 538 2.0E-90 T 13-09-2016 THL1_RS20895 346a0d6db73630ae1e880c76e5644e95 547 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 495 514 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS20895 346a0d6db73630ae1e880c76e5644e95 547 SUPERFAMILY SSF47203 388 537 7.41E-38 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS20895 346a0d6db73630ae1e880c76e5644e95 547 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 265 373 4.4E-15 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS01890 959548ef1c7860b12e711f94ba678870 429 PANTHER PTHR21266:SF2 33 412 3.3E-115 T 13-09-2016 THL1_RS01890 959548ef1c7860b12e711f94ba678870 429 PANTHER PTHR21266 33 412 3.3E-115 T 13-09-2016 THL1_RS01890 959548ef1c7860b12e711f94ba678870 429 SUPERFAMILY SSF50022 25 167 2.23E-45 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS01890 959548ef1c7860b12e711f94ba678870 429 Gene3D G3DSA:2.102.10.10 55 158 1.9E-25 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS01890 959548ef1c7860b12e711f94ba678870 429 Gene3D G3DSA:3.90.380.10 159 410 1.5E-19 T 13-09-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 THL1_RS01890 959548ef1c7860b12e711f94ba678870 429 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 91 111 3.6E-29 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS01890 959548ef1c7860b12e711f94ba678870 429 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 152 178 3.6E-29 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS01890 959548ef1c7860b12e711f94ba678870 429 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 40 65 3.6E-29 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS01890 959548ef1c7860b12e711f94ba678870 429 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 189 211 3.6E-29 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS01890 959548ef1c7860b12e711f94ba678870 429 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 112 132 3.6E-29 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS01890 959548ef1c7860b12e711f94ba678870 429 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 70 85 3.6E-29 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS01890 959548ef1c7860b12e711f94ba678870 429 Pfam PF00355 Rieske [2Fe-2S] domain 56 131 1.4E-16 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS01890 959548ef1c7860b12e711f94ba678870 429 SUPERFAMILY SSF55961 168 413 6.28E-53 T 13-09-2016 THL1_RS01890 959548ef1c7860b12e711f94ba678870 429 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 188 412 8.6E-46 T 13-09-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 SUPERFAMILY SSF82866 803 1004 3.66E-45 T 13-09-2016 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 SUPERFAMILY SSF82693 267 323 5.41E-23 T 13-09-2016 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 SUPERFAMILY SSF82693 137 181 5.41E-23 T 13-09-2016 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 Gene3D G3DSA:3.30.70.1440 794 823 7.4E-8 T 13-09-2016 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 Gene3D G3DSA:3.30.70.1440 651 697 7.4E-8 T 13-09-2016 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 SUPERFAMILY SSF82693 650 698 5.75E-14 T 13-09-2016 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 SUPERFAMILY SSF82693 785 832 5.75E-14 T 13-09-2016 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 SUPERFAMILY SSF82714 699 784 4.97E-19 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 SUPERFAMILY SSF82693 42 132 2.09E-21 T 13-09-2016 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 PANTHER PTHR32063:SF14 1 1012 0.0 T 13-09-2016 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 Pfam PF00873 AcrB/AcrD/AcrF family 6 1002 8.5E-278 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 Gene3D G3DSA:3.30.70.1430 42 141 3.6E-25 T 13-09-2016 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 Gene3D G3DSA:3.30.70.1430 555 650 4.8E-15 T 13-09-2016 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 SUPERFAMILY SSF82693 553 650 5.75E-22 T 13-09-2016 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 Gene3D G3DSA:3.30.2090.10 183 265 9.7E-19 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 Gene3D G3DSA:3.30.2090.10 699 783 9.3E-20 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 Gene3D G3DSA:1.10.3850.10 271 491 2.6E-63 T 13-09-2016 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 SUPERFAMILY SSF82866 290 490 1.44E-52 T 13-09-2016 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 Gene3D G3DSA:1.20.1640.10 824 1007 3.8E-47 T 13-09-2016 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 PANTHER PTHR32063 1 1012 0.0 T 13-09-2016 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 SUPERFAMILY SSF82714 183 265 1.31E-16 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 2.7E-77 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 2.7E-77 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 2.7E-77 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 2.7E-77 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 2.7E-77 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 2.7E-77 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 PRINTS PR00702 Acriflavin resistance protein family signature 603 617 2.7E-77 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 2.7E-77 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS23390 b47775cfd933f0fbe2fbb9ffc281e5b4 1017 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 2.7E-77 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS10375 b4b297de01db2b3450c9dcf1ac9ac163 984 SUPERFAMILY SSF103190 176 235 4.71E-6 T 13-09-2016 IPR029151 Periplasmic sensor domain-like THL1_RS10375 b4b297de01db2b3450c9dcf1ac9ac163 984 Gene3D G3DSA:3.30.450.20 215 346 1.0E-6 T 13-09-2016 THL1_RS10375 b4b297de01db2b3450c9dcf1ac9ac163 984 SUPERFAMILY SSF109604 838 951 5.02E-9 T 13-09-2016 THL1_RS10375 b4b297de01db2b3450c9dcf1ac9ac163 984 SMART SM00471 610 922 4.3E-6 T 13-09-2016 IPR003607 HD/PDEase domain THL1_RS10375 b4b297de01db2b3450c9dcf1ac9ac163 984 Pfam PF13487 HD domain 839 904 6.2E-25 T 13-09-2016 THL1_RS10375 b4b297de01db2b3450c9dcf1ac9ac163 984 Pfam PF00672 HAMP domain 349 415 2.2E-8 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS10375 b4b297de01db2b3450c9dcf1ac9ac163 984 Gene3D G3DSA:3.30.450.20 89 214 1.3E-20 T 13-09-2016 THL1_RS10375 b4b297de01db2b3450c9dcf1ac9ac163 984 SUPERFAMILY SSF55781 532 595 8.24E-7 T 13-09-2016 IPR029016 GAF domain-like THL1_RS10375 b4b297de01db2b3450c9dcf1ac9ac163 984 SUPERFAMILY SSF55781 414 500 8.24E-7 T 13-09-2016 IPR029016 GAF domain-like THL1_RS10375 b4b297de01db2b3450c9dcf1ac9ac163 984 SUPERFAMILY SSF109604 606 693 1.98E-8 T 13-09-2016 THL1_RS10375 b4b297de01db2b3450c9dcf1ac9ac163 984 Pfam PF02743 Cache domain 43 328 1.9E-12 T 13-09-2016 IPR033479 Double Cache domain 1 THL1_RS10375 b4b297de01db2b3450c9dcf1ac9ac163 984 Gene3D G3DSA:1.10.3210.10 600 679 9.3E-7 T 13-09-2016 IPR006674 HD domain THL1_RS11880 606554800e60fdbf8a389968a0f10f26 528 PANTHER PTHR35093:SF2 132 223 4.4E-125 T 13-09-2016 THL1_RS11880 606554800e60fdbf8a389968a0f10f26 528 PANTHER PTHR35093:SF2 316 519 4.4E-125 T 13-09-2016 THL1_RS11880 606554800e60fdbf8a389968a0f10f26 528 PANTHER PTHR35093:SF2 245 300 4.4E-125 T 13-09-2016 THL1_RS11880 606554800e60fdbf8a389968a0f10f26 528 PANTHER PTHR35093:SF2 2 116 4.4E-125 T 13-09-2016 THL1_RS11880 606554800e60fdbf8a389968a0f10f26 528 SUPERFAMILY SSF56935 33 528 3.4E-59 T 13-09-2016 THL1_RS11880 606554800e60fdbf8a389968a0f10f26 528 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 13 528 9.9E-119 T 13-09-2016 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) THL1_RS11880 606554800e60fdbf8a389968a0f10f26 528 PANTHER PTHR35093 132 223 4.4E-125 T 13-09-2016 THL1_RS11880 606554800e60fdbf8a389968a0f10f26 528 PANTHER PTHR35093 316 519 4.4E-125 T 13-09-2016 THL1_RS11880 606554800e60fdbf8a389968a0f10f26 528 PANTHER PTHR35093 245 300 4.4E-125 T 13-09-2016 THL1_RS11880 606554800e60fdbf8a389968a0f10f26 528 PANTHER PTHR35093 2 116 4.4E-125 T 13-09-2016 THL1_RS11880 606554800e60fdbf8a389968a0f10f26 528 Gene3D G3DSA:2.40.160.60 34 528 1.2E-106 T 13-09-2016 THL1_RS14215 4946de7d340683f525718647772bf236 622 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 34 586 3.1E-237 T 13-09-2016 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 THL1_RS14215 4946de7d340683f525718647772bf236 622 Pfam PF01011 PQQ enzyme repeat 532 568 1.2E-9 T 13-09-2016 IPR002372 Pyrrolo-quinoline quinone repeat THL1_RS14215 4946de7d340683f525718647772bf236 622 ProSitePatterns PS00364 Bacterial quinoprotein dehydrogenases signature 2. 282 303 - T 13-09-2016 IPR001479 Quinoprotein dehydrogenase, conserved site GO:0030288|GO:0055114 THL1_RS14215 4946de7d340683f525718647772bf236 622 SMART SM00564 475 517 95.0 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS14215 4946de7d340683f525718647772bf236 622 SMART SM00564 527 558 1.8E-6 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS14215 4946de7d340683f525718647772bf236 622 SMART SM00564 97 129 1.6E-7 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS14215 4946de7d340683f525718647772bf236 622 SMART SM00564 368 397 790.0 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS14215 4946de7d340683f525718647772bf236 622 SMART SM00564 147 178 2.0E-6 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS14215 4946de7d340683f525718647772bf236 622 SMART SM00564 197 235 110.0 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS14215 4946de7d340683f525718647772bf236 622 PANTHER PTHR32303:SF2 431 621 3.0E-138 T 13-09-2016 THL1_RS14215 4946de7d340683f525718647772bf236 622 PANTHER PTHR32303:SF2 10 237 3.0E-138 T 13-09-2016 THL1_RS14215 4946de7d340683f525718647772bf236 622 PANTHER PTHR32303:SF2 262 392 3.0E-138 T 13-09-2016 THL1_RS14215 4946de7d340683f525718647772bf236 622 SUPERFAMILY SSF50998 45 615 2.22E-148 T 13-09-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THL1_RS14215 4946de7d340683f525718647772bf236 622 Gene3D G3DSA:2.140.10.10 49 618 9.7E-147 T 13-09-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain THL1_RS14215 4946de7d340683f525718647772bf236 622 PANTHER PTHR32303 431 621 3.0E-138 T 13-09-2016 THL1_RS14215 4946de7d340683f525718647772bf236 622 PANTHER PTHR32303 10 237 3.0E-138 T 13-09-2016 THL1_RS14215 4946de7d340683f525718647772bf236 622 PANTHER PTHR32303 262 392 3.0E-138 T 13-09-2016 THL1_RS14215 4946de7d340683f525718647772bf236 622 Pfam PF13360 PQQ-like domain 91 249 6.2E-17 T 13-09-2016 IPR002372 Pyrrolo-quinoline quinone repeat THL1_RS19575 63f64ab9514ebd3684011606365b8ed5 117 SUPERFAMILY SSF47226 4 115 8.9E-27 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS19575 63f64ab9514ebd3684011606365b8ed5 117 Gene3D G3DSA:1.20.120.160 5 110 8.8E-27 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS19575 63f64ab9514ebd3684011606365b8ed5 117 SMART SM00073 14 108 3.8E-4 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS19575 63f64ab9514ebd3684011606365b8ed5 117 Pfam PF01627 Hpt domain 25 97 6.1E-16 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS24500 c6200235010d6e2c476ca502cfd0f894 557 Gene3D G3DSA:3.40.50.300 432 510 3.0E-6 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24500 c6200235010d6e2c476ca502cfd0f894 557 Pfam PF02463 RecF/RecN/SMC N terminal domain 6 510 2.9E-15 T 13-09-2016 IPR003395 RecF/RecN/SMC, N-terminal THL1_RS24500 c6200235010d6e2c476ca502cfd0f894 557 SUPERFAMILY SSF52540 2 50 9.94E-30 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24500 c6200235010d6e2c476ca502cfd0f894 557 SUPERFAMILY SSF52540 284 514 9.94E-30 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24500 c6200235010d6e2c476ca502cfd0f894 557 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 552 7.0E-160 T 13-09-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 THL1_RS24500 c6200235010d6e2c476ca502cfd0f894 557 SUPERFAMILY SSF52540 1 217 1.35E-66 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24500 c6200235010d6e2c476ca502cfd0f894 557 Gene3D G3DSA:3.40.50.300 1 199 2.5E-69 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24500 c6200235010d6e2c476ca502cfd0f894 557 Gene3D G3DSA:3.80.10.10 200 268 8.5E-5 T 13-09-2016 IPR032675 Leucine-rich repeat domain, L domain-like THL1_RS24500 c6200235010d6e2c476ca502cfd0f894 557 PIRSF PIRSF003128 1 557 5.2E-161 T 13-09-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 THL1_RS24500 c6200235010d6e2c476ca502cfd0f894 557 PANTHER PTHR11059 2 556 1.7E-172 T 13-09-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 THL1_RS19590 b09586d5cdd5728c3caffaf72f3397b3 149 Pfam PF02050 Flagellar FliJ protein 22 143 1.2E-36 T 13-09-2016 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 THL1_RS19590 b09586d5cdd5728c3caffaf72f3397b3 149 PRINTS PR01004 Flagellar FliJ protein signature 6 28 1.1E-9 T 13-09-2016 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 THL1_RS19590 b09586d5cdd5728c3caffaf72f3397b3 149 PRINTS PR01004 Flagellar FliJ protein signature 110 128 1.1E-9 T 13-09-2016 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 THL1_RS19590 b09586d5cdd5728c3caffaf72f3397b3 149 PRINTS PR01004 Flagellar FliJ protein signature 65 86 1.1E-9 T 13-09-2016 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 THL1_RS19590 b09586d5cdd5728c3caffaf72f3397b3 149 PRINTS PR01004 Flagellar FliJ protein signature 128 148 1.1E-9 T 13-09-2016 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 THL1_RS19590 b09586d5cdd5728c3caffaf72f3397b3 149 PRINTS PR01004 Flagellar FliJ protein signature 46 63 1.1E-9 T 13-09-2016 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 THL1_RS19590 b09586d5cdd5728c3caffaf72f3397b3 149 PANTHER PTHR38786 3 146 5.5E-36 T 13-09-2016 THL1_RS19590 b09586d5cdd5728c3caffaf72f3397b3 149 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 7 145 8.9E-34 T 13-09-2016 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 THL1_RS19590 b09586d5cdd5728c3caffaf72f3397b3 149 PIRSF PIRSF019404 1 149 1.0E-38 T 13-09-2016 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 THL1_RS20575 bc5ba721b43fa727e6453bfa61d6c282 332 PANTHER PTHR11695 15 331 6.3E-115 T 13-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 THL1_RS20575 bc5ba721b43fa727e6453bfa61d6c282 332 Pfam PF00107 Zinc-binding dehydrogenase 153 266 7.2E-32 T 13-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THL1_RS20575 bc5ba721b43fa727e6453bfa61d6c282 332 Gene3D G3DSA:3.90.180.10 1 145 1.9E-37 T 13-09-2016 IPR011032 GroES-like THL1_RS20575 bc5ba721b43fa727e6453bfa61d6c282 332 PANTHER PTHR11695:SF31 15 331 6.3E-115 T 13-09-2016 THL1_RS20575 bc5ba721b43fa727e6453bfa61d6c282 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 1.3E-8 T 13-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THL1_RS20575 bc5ba721b43fa727e6453bfa61d6c282 332 SUPERFAMILY SSF50129 1 142 1.89E-34 T 13-09-2016 IPR011032 GroES-like THL1_RS20575 bc5ba721b43fa727e6453bfa61d6c282 332 SMART SM00829 10 324 6.4E-45 T 13-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THL1_RS20575 bc5ba721b43fa727e6453bfa61d6c282 332 SUPERFAMILY SSF51735 121 284 1.14E-47 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20575 bc5ba721b43fa727e6453bfa61d6c282 332 Gene3D G3DSA:3.40.50.720 146 263 3.0E-39 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07700 5506390b20b9c255ce608b7f60f794a9 339 PANTHER PTHR30482:SF2 4 336 2.1E-74 T 13-09-2016 THL1_RS07700 5506390b20b9c255ce608b7f60f794a9 339 Pfam PF02653 Branched-chain amino acid transport system / permease component 30 304 1.7E-33 T 13-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 THL1_RS07700 5506390b20b9c255ce608b7f60f794a9 339 PANTHER PTHR30482 4 336 2.1E-74 T 13-09-2016 THL1_RS23680 1d65be33b34464b628e8bb42f5efc8c9 104 SUPERFAMILY SSF54909 1 100 1.13E-12 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS23680 1d65be33b34464b628e8bb42f5efc8c9 104 Pfam PF07110 EthD domain 18 87 1.8E-4 T 13-09-2016 IPR009799 EthD domain THL1_RS23680 1d65be33b34464b628e8bb42f5efc8c9 104 Gene3D G3DSA:3.30.70.900 4 98 8.0E-27 T 13-09-2016 THL1_RS23680 1d65be33b34464b628e8bb42f5efc8c9 104 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 101 2.3E-16 T 13-09-2016 IPR009799 EthD domain THL1_RS23680 1d65be33b34464b628e8bb42f5efc8c9 104 PANTHER PTHR40260 1 104 8.6E-12 T 13-09-2016 THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 PANTHER PTHR24423:SF485 382 905 3.7E-156 T 13-09-2016 THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 SUPERFAMILY SSF55785 533 658 2.49E-15 T 13-09-2016 IPR000014 PAS domain THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 791 902 1.8E-19 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 SUPERFAMILY SSF55874 734 905 5.24E-39 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 Gene3D G3DSA:3.30.450.20 551 658 7.5E-13 T 13-09-2016 THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 Gene3D G3DSA:3.30.450.20 285 406 2.6E-9 T 13-09-2016 THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 PANTHER PTHR24423 382 905 3.7E-156 T 13-09-2016 THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 SUPERFAMILY SSF55785 405 534 6.41E-16 T 13-09-2016 IPR000014 PAS domain THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 Pfam PF00512 His Kinase A (phospho-acceptor) domain 678 744 1.0E-7 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 PRINTS PR00344 Bacterial sensor protein C-terminal signature 865 883 1.3E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 PRINTS PR00344 Bacterial sensor protein C-terminal signature 834 848 1.3E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 PRINTS PR00344 Bacterial sensor protein C-terminal signature 852 862 1.3E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 PRINTS PR00344 Bacterial sensor protein C-terminal signature 888 901 1.3E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 544 669 1.4E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 419 542 1.2E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 SMART SM00387 789 904 9.0E-29 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 SMART SM00091 293 360 15.0 T 13-09-2016 IPR000014 PAS domain THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 SMART SM00091 548 614 3.1E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 SMART SM00091 420 489 8.3E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 SUPERFAMILY SSF47384 673 743 3.53E-8 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 SMART SM00388 677 747 1.1E-5 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 Pfam PF08448 PAS fold 554 663 1.5E-7 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 Gene3D G3DSA:3.30.565.10 747 902 1.0E-40 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 Pfam PF08447 PAS fold 447 529 1.4E-13 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 Gene3D G3DSA:3.30.450.20 447 550 9.2E-23 T 13-09-2016 THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 Gene3D G3DSA:1.10.287.130 675 738 0.001 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS25295 322625b7f2ec6d59893b8509fdd835b2 931 SMART SM00086 494 536 9.9E-5 T 13-09-2016 IPR001610 PAC motif THL1_RS05640 5cd6deb2e1863a9274ce876c4df241cb 356 Gene3D G3DSA:3.40.50.2000 4 192 6.0E-71 T 13-09-2016 THL1_RS05640 5cd6deb2e1863a9274ce876c4df241cb 356 Gene3D G3DSA:3.40.50.2000 252 330 1.1E-5 T 13-09-2016 THL1_RS05640 5cd6deb2e1863a9274ce876c4df241cb 356 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 4 349 9.1E-110 T 13-09-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS05640 5cd6deb2e1863a9274ce876c4df241cb 356 PANTHER PTHR21015 4 355 1.1E-124 T 13-09-2016 THL1_RS05640 5cd6deb2e1863a9274ce876c4df241cb 356 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 5 354 37.529 T 13-09-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS05640 5cd6deb2e1863a9274ce876c4df241cb 356 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 182 334 2.7E-36 T 13-09-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS05640 5cd6deb2e1863a9274ce876c4df241cb 356 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 5 141 8.1E-43 T 13-09-2016 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS05640 5cd6deb2e1863a9274ce876c4df241cb 356 SUPERFAMILY SSF53756 4 354 1.62E-118 T 13-09-2016 THL1_RS05640 5cd6deb2e1863a9274ce876c4df241cb 356 PANTHER PTHR21015:SF22 4 355 1.1E-124 T 13-09-2016 THL1_RS00980 8679a36c87600cade763938042a3151f 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 155 169 3.8E-68 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00980 8679a36c87600cade763938042a3151f 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 178 197 3.8E-68 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00980 8679a36c87600cade763938042a3151f 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 91 104 3.8E-68 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00980 8679a36c87600cade763938042a3151f 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 75 89 3.8E-68 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00980 8679a36c87600cade763938042a3151f 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 32 48 3.8E-68 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00980 8679a36c87600cade763938042a3151f 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 48 69 3.8E-68 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00980 8679a36c87600cade763938042a3151f 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 124 140 3.8E-68 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00980 8679a36c87600cade763938042a3151f 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 215 234 3.8E-68 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00980 8679a36c87600cade763938042a3151f 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 265 284 3.8E-68 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00980 8679a36c87600cade763938042a3151f 366 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 310 336 3.8E-68 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00980 8679a36c87600cade763938042a3151f 366 PANTHER PTHR30222 1 366 2.5E-215 T 13-09-2016 THL1_RS00980 8679a36c87600cade763938042a3151f 366 SUPERFAMILY SSF53850 26 365 7.95E-107 T 13-09-2016 THL1_RS00980 8679a36c87600cade763938042a3151f 366 Pfam PF13416 Bacterial extracellular solute-binding protein 42 330 7.4E-36 T 13-09-2016 THL1_RS00980 8679a36c87600cade763938042a3151f 366 Gene3D G3DSA:3.40.190.10 41 147 4.8E-15 T 13-09-2016 THL1_RS00980 8679a36c87600cade763938042a3151f 366 PANTHER PTHR30222:SF11 1 366 2.5E-215 T 13-09-2016 THL1_RS00980 8679a36c87600cade763938042a3151f 366 Gene3D G3DSA:3.40.190.10 148 315 6.8E-71 T 13-09-2016 THL1_RS00980 8679a36c87600cade763938042a3151f 366 PIRSF PIRSF019574 1 366 4.6E-145 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS10895 aac8b95987d4d8d07a8eb2b34904b575 437 Pfam PF05525 Branched-chain amino acid transport protein 7 427 2.6E-158 T 13-09-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 THL1_RS10895 aac8b95987d4d8d07a8eb2b34904b575 437 PANTHER PTHR30588 1 437 1.7E-220 T 13-09-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 THL1_RS10895 aac8b95987d4d8d07a8eb2b34904b575 437 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 13 414 3.9E-160 T 13-09-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 THL1_RS10895 aac8b95987d4d8d07a8eb2b34904b575 437 PANTHER PTHR30588:SF0 1 437 1.7E-220 T 13-09-2016 THL1_RS26760 920a1165324f1c33650a7a8de5e66073 197 PANTHER PTHR23133:SF2 1 197 3.8E-104 T 13-09-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 THL1_RS26760 920a1165324f1c33650a7a8de5e66073 197 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 4 197 42.543 T 13-09-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 THL1_RS26760 920a1165324f1c33650a7a8de5e66073 197 Gene3D G3DSA:3.30.230.40 3 90 8.7E-39 T 13-09-2016 THL1_RS26760 920a1165324f1c33650a7a8de5e66073 197 SUPERFAMILY SSF54211 89 181 1.39E-34 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS26760 920a1165324f1c33650a7a8de5e66073 197 PANTHER PTHR23133 1 197 3.8E-104 T 13-09-2016 THL1_RS26760 920a1165324f1c33650a7a8de5e66073 197 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 63 76 - T 13-09-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 THL1_RS26760 920a1165324f1c33650a7a8de5e66073 197 SUPERFAMILY SSF54211 4 88 3.67E-34 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS26760 920a1165324f1c33650a7a8de5e66073 197 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 13-09-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 THL1_RS26760 920a1165324f1c33650a7a8de5e66073 197 Gene3D G3DSA:3.30.230.40 92 197 1.8E-31 T 13-09-2016 THL1_RS26760 920a1165324f1c33650a7a8de5e66073 197 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 34 176 4.7E-62 T 13-09-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 THL1_RS25275 296990d7374439bb25e2cc7859501bd4 210 SUPERFAMILY SSF81342 5 206 1.8E-53 T 13-09-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 THL1_RS25275 296990d7374439bb25e2cc7859501bd4 210 Pfam PF01292 Prokaryotic cytochrome b561 7 184 1.3E-24 T 13-09-2016 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THL1_RS25275 296990d7374439bb25e2cc7859501bd4 210 PANTHER PTHR30074 1 206 5.4E-73 T 13-09-2016 THL1_RS25275 296990d7374439bb25e2cc7859501bd4 210 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 5 204 5.9E-61 T 13-09-2016 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 THL1_RS25275 296990d7374439bb25e2cc7859501bd4 210 Gene3D G3DSA:1.20.950.20 2 206 8.3E-66 T 13-09-2016 THL1_RS15300 d3af127b203f67247aff140bf32d763b 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 2.2E-13 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS15300 d3af127b203f67247aff140bf32d763b 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 2.2E-13 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS15300 d3af127b203f67247aff140bf32d763b 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 2.2E-13 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS15300 d3af127b203f67247aff140bf32d763b 210 SUPERFAMILY SSF52172 6 137 1.04E-32 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS15300 d3af127b203f67247aff140bf32d763b 210 SMART SM00421 145 202 1.2E-20 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS15300 d3af127b203f67247aff140bf32d763b 210 PANTHER PTHR26402:SF151 7 210 6.8E-69 T 13-09-2016 THL1_RS15300 d3af127b203f67247aff140bf32d763b 210 SUPERFAMILY SSF46894 143 209 9.18E-22 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS15300 d3af127b203f67247aff140bf32d763b 210 SMART SM00448 7 120 2.9E-28 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS15300 d3af127b203f67247aff140bf32d763b 210 Gene3D G3DSA:1.10.10.10 125 208 2.2E-28 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS15300 d3af127b203f67247aff140bf32d763b 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 5.0E-18 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS15300 d3af127b203f67247aff140bf32d763b 210 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS15300 d3af127b203f67247aff140bf32d763b 210 Gene3D G3DSA:3.40.50.2300 5 124 4.5E-34 T 13-09-2016 THL1_RS15300 d3af127b203f67247aff140bf32d763b 210 Pfam PF00072 Response regulator receiver domain 9 121 2.6E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS15300 d3af127b203f67247aff140bf32d763b 210 PANTHER PTHR26402 7 210 6.8E-69 T 13-09-2016 THL1_RS25110 bca7ca2c3cf8ce66375c89209c6cdfa9 133 PANTHER PTHR30204 1 133 2.4E-64 T 13-09-2016 THL1_RS25110 bca7ca2c3cf8ce66375c89209c6cdfa9 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 2.2E-9 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS25110 bca7ca2c3cf8ce66375c89209c6cdfa9 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.2E-9 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS25110 bca7ca2c3cf8ce66375c89209c6cdfa9 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.2E-9 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS25110 bca7ca2c3cf8ce66375c89209c6cdfa9 133 Gene3D G3DSA:1.10.1660.10 56 131 1.1E-30 T 13-09-2016 THL1_RS25110 bca7ca2c3cf8ce66375c89209c6cdfa9 133 SMART SM00422 1 70 2.4E-31 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS25110 bca7ca2c3cf8ce66375c89209c6cdfa9 133 Pfam PF09278 MerR, DNA binding 45 108 5.1E-20 T 13-09-2016 IPR015358 Transcription regulator MerR, DNA binding THL1_RS25110 bca7ca2c3cf8ce66375c89209c6cdfa9 133 Pfam PF00376 MerR family regulatory protein 2 39 1.0E-15 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS25110 bca7ca2c3cf8ce66375c89209c6cdfa9 133 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 1 126 5.8E-54 T 13-09-2016 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 THL1_RS25110 bca7ca2c3cf8ce66375c89209c6cdfa9 133 Gene3D G3DSA:1.10.1660.10 1 55 9.8E-26 T 13-09-2016 THL1_RS25110 bca7ca2c3cf8ce66375c89209c6cdfa9 133 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS25110 bca7ca2c3cf8ce66375c89209c6cdfa9 133 SUPERFAMILY SSF46955 1 126 6.96E-39 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS25110 bca7ca2c3cf8ce66375c89209c6cdfa9 133 PANTHER PTHR30204:SF16 1 133 2.4E-64 T 13-09-2016 THL1_RS19860 d3bcfe371aa4dea231115a143f6ca9e2 249 Pfam PF07317 Flagellar regulator YcgR 17 121 2.0E-25 T 13-09-2016 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal THL1_RS19860 d3bcfe371aa4dea231115a143f6ca9e2 249 Pfam PF07238 PilZ domain 124 235 4.1E-8 T 13-09-2016 IPR009875 PilZ domain GO:0035438 THL1_RS19860 d3bcfe371aa4dea231115a143f6ca9e2 249 Gene3D G3DSA:2.30.110.10 14 124 1.2E-47 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS19860 d3bcfe371aa4dea231115a143f6ca9e2 249 Gene3D G3DSA:2.40.10.220 125 246 9.7E-39 T 13-09-2016 THL1_RS01095 127a5d4b32647a5b9a9bce7dcc47eea4 239 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 18 123 1.6E-11 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS01095 127a5d4b32647a5b9a9bce7dcc47eea4 239 SUPERFAMILY SSF161098 19 216 1.57E-32 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01095 127a5d4b32647a5b9a9bce7dcc47eea4 239 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 223 1.9E-16 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01095 127a5d4b32647a5b9a9bce7dcc47eea4 239 PANTHER PTHR30133 13 239 9.1E-69 T 13-09-2016 THL1_RS01095 127a5d4b32647a5b9a9bce7dcc47eea4 239 Gene3D G3DSA:1.10.3720.10 19 230 1.6E-32 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS20470 23186e8cb3d65c6bc627b60f40ed6c62 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 72 3.2E-15 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS20470 23186e8cb3d65c6bc627b60f40ed6c62 316 Pfam PF03466 LysR substrate binding domain 98 294 3.2E-30 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS20470 23186e8cb3d65c6bc627b60f40ed6c62 316 Gene3D G3DSA:1.10.10.10 10 92 2.4E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20470 23186e8cb3d65c6bc627b60f40ed6c62 316 PANTHER PTHR30579 8 310 2.8E-72 T 13-09-2016 THL1_RS20470 23186e8cb3d65c6bc627b60f40ed6c62 316 Gene3D G3DSA:3.40.190.10 101 200 4.4E-21 T 13-09-2016 THL1_RS20470 23186e8cb3d65c6bc627b60f40ed6c62 316 SUPERFAMILY SSF46785 9 121 8.47E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20470 23186e8cb3d65c6bc627b60f40ed6c62 316 PANTHER PTHR30579:SF3 8 310 2.8E-72 T 13-09-2016 THL1_RS20470 23186e8cb3d65c6bc627b60f40ed6c62 316 SUPERFAMILY SSF53850 98 296 1.41E-33 T 13-09-2016 THL1_RS22460 a118f45fea1c1ec8229017629497f8fd 348 Hamap MF_00268 Protein RecA [recA]. 5 329 51.089 T 13-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THL1_RS22460 a118f45fea1c1ec8229017629497f8fd 348 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 324 2.0E-169 T 13-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THL1_RS22460 a118f45fea1c1ec8229017629497f8fd 348 SUPERFAMILY SSF52540 7 267 4.97E-65 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22460 a118f45fea1c1ec8229017629497f8fd 348 PRINTS PR00142 RecA protein signature 127 156 3.1E-83 T 13-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THL1_RS22460 a118f45fea1c1ec8229017629497f8fd 348 PRINTS PR00142 RecA protein signature 243 272 3.1E-83 T 13-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THL1_RS22460 a118f45fea1c1ec8229017629497f8fd 348 PRINTS PR00142 RecA protein signature 210 238 3.1E-83 T 13-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THL1_RS22460 a118f45fea1c1ec8229017629497f8fd 348 PRINTS PR00142 RecA protein signature 165 194 3.1E-83 T 13-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THL1_RS22460 a118f45fea1c1ec8229017629497f8fd 348 PRINTS PR00142 RecA protein signature 297 314 3.1E-83 T 13-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THL1_RS22460 a118f45fea1c1ec8229017629497f8fd 348 PRINTS PR00142 RecA protein signature 93 122 3.1E-83 T 13-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THL1_RS22460 a118f45fea1c1ec8229017629497f8fd 348 SMART SM00382 57 228 1.7E-10 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS22460 a118f45fea1c1ec8229017629497f8fd 348 Gene3D G3DSA:3.40.50.300 27 267 1.2E-84 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22460 a118f45fea1c1ec8229017629497f8fd 348 SUPERFAMILY SSF54752 269 325 1.57E-19 T 13-09-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal THL1_RS22460 a118f45fea1c1ec8229017629497f8fd 348 PANTHER PTHR22942:SF1 3 335 9.2E-204 T 13-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THL1_RS22460 a118f45fea1c1ec8229017629497f8fd 348 Gene3D G3DSA:3.30.250.10 269 326 6.1E-26 T 13-09-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal THL1_RS22460 a118f45fea1c1ec8229017629497f8fd 348 PANTHER PTHR22942 3 335 9.2E-204 T 13-09-2016 THL1_RS22460 a118f45fea1c1ec8229017629497f8fd 348 ProSitePatterns PS00321 recA signature. 213 221 - T 13-09-2016 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 THL1_RS22460 a118f45fea1c1ec8229017629497f8fd 348 Pfam PF00154 recA bacterial DNA recombination protein 7 267 1.2E-144 T 13-09-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 PANTHER PTHR24423:SF564 238 591 4.0E-135 T 13-09-2016 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 SUPERFAMILY SSF47384 358 439 2.55E-16 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 SMART SM00304 191 243 1.1E-9 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 SMART SM00091 254 319 1.1E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 Gene3D G3DSA:1.10.287.130 363 435 2.8E-15 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 252 369 3.1E-10 T 13-09-2016 IPR000014 PAS domain THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 Pfam PF08448 PAS fold 260 366 2.9E-14 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 SUPERFAMILY SSF158472 191 239 1.7E-6 T 13-09-2016 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 PANTHER PTHR24423 238 591 4.0E-135 T 13-09-2016 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 SMART SM00387 485 591 2.8E-30 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 540 550 2.1E-18 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 522 536 2.1E-18 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 577 590 2.1E-18 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 PRINTS PR00344 Bacterial sensor protein C-terminal signature 553 571 2.1E-18 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 Pfam PF00512 His Kinase A (phospho-acceptor) domain 372 439 6.2E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 PANTHER PTHR24423:SF564 1 31 4.0E-135 T 13-09-2016 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 487 590 1.6E-22 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 PANTHER PTHR24423 1 31 4.0E-135 T 13-09-2016 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 Pfam PF16767 Sensor domain of alginate biosynthesis sensor protein KinB 35 154 6.6E-39 T 13-09-2016 IPR031909 Alginate biosynthesis sensor protein KinB, sensor domain THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 Pfam PF00672 HAMP domain 172 239 2.0E-11 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 SMART SM00388 371 439 1.5E-17 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 SUPERFAMILY SSF55874 428 591 1.96E-48 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 SUPERFAMILY SSF55785 247 363 2.27E-16 T 13-09-2016 IPR000014 PAS domain THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 Gene3D G3DSA:3.30.450.20 249 362 3.0E-19 T 13-09-2016 THL1_RS00415 b90e6c3eaf533e63108bb1f350c17f98 591 Gene3D G3DSA:3.30.565.10 443 591 1.5E-45 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS21840 a9a12b5d826f7f10de7085d4e38f46b8 348 SUPERFAMILY SSF53335 96 348 3.22E-33 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS21840 a9a12b5d826f7f10de7085d4e38f46b8 348 Gene3D G3DSA:1.10.10.10 26 84 1.9E-7 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS21840 a9a12b5d826f7f10de7085d4e38f46b8 348 SUPERFAMILY SSF46785 17 87 3.36E-8 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS21840 a9a12b5d826f7f10de7085d4e38f46b8 348 PANTHER PTHR10108 143 280 2.6E-22 T 13-09-2016 THL1_RS21840 a9a12b5d826f7f10de7085d4e38f46b8 348 PANTHER PTHR10108 300 334 2.6E-22 T 13-09-2016 THL1_RS21840 a9a12b5d826f7f10de7085d4e38f46b8 348 Gene3D G3DSA:3.40.50.150 164 331 2.7E-32 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS21840 a9a12b5d826f7f10de7085d4e38f46b8 348 Pfam PF13847 Methyltransferase domain 167 288 4.0E-19 T 13-09-2016 IPR025714 Methyltransferase domain THL1_RS23440 cd742ab61c0ca3a4b6b88d0dc3902a83 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 193 1.5E-4 T 13-09-2016 THL1_RS23440 cd742ab61c0ca3a4b6b88d0dc3902a83 252 SUPERFAMILY SSF51735 4 250 3.01E-73 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23440 cd742ab61c0ca3a4b6b88d0dc3902a83 252 PANTHER PTHR24322 10 194 1.7E-46 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23440 cd742ab61c0ca3a4b6b88d0dc3902a83 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.0E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23440 cd742ab61c0ca3a4b6b88d0dc3902a83 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 3.0E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23440 cd742ab61c0ca3a4b6b88d0dc3902a83 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 3.0E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23440 cd742ab61c0ca3a4b6b88d0dc3902a83 252 Gene3D G3DSA:3.40.50.720 2 250 3.9E-80 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23440 cd742ab61c0ca3a4b6b88d0dc3902a83 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 250 6.2E-56 T 13-09-2016 THL1_RS23440 cd742ab61c0ca3a4b6b88d0dc3902a83 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 7.8E-35 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23440 cd742ab61c0ca3a4b6b88d0dc3902a83 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 7.8E-35 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23440 cd742ab61c0ca3a4b6b88d0dc3902a83 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 7.8E-35 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23440 cd742ab61c0ca3a4b6b88d0dc3902a83 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 7.8E-35 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23440 cd742ab61c0ca3a4b6b88d0dc3902a83 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 7.8E-35 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23440 cd742ab61c0ca3a4b6b88d0dc3902a83 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 7.8E-35 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS10650 e1707087be508da8defeacb7163aa6b0 174 Pfam PF03734 L,D-transpeptidase catalytic domain 7 155 2.9E-18 T 13-09-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 THL1_RS10650 e1707087be508da8defeacb7163aa6b0 174 PANTHER PTHR30582 9 160 8.7E-17 T 13-09-2016 THL1_RS10650 e1707087be508da8defeacb7163aa6b0 174 SUPERFAMILY SSF141523 6 60 3.27E-24 T 13-09-2016 THL1_RS10650 e1707087be508da8defeacb7163aa6b0 174 SUPERFAMILY SSF141523 88 160 3.27E-24 T 13-09-2016 THL1_RS10650 e1707087be508da8defeacb7163aa6b0 174 Gene3D G3DSA:2.40.440.10 6 160 6.3E-26 T 13-09-2016 THL1_RS12555 0eede2f99d1f8d14a2335bfe6cc2b432 463 Gene3D G3DSA:3.40.309.10 245 431 3.3E-56 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS12555 0eede2f99d1f8d14a2335bfe6cc2b432 463 SUPERFAMILY SSF53720 4 460 3.67E-131 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS12555 0eede2f99d1f8d14a2335bfe6cc2b432 463 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 230 237 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS12555 0eede2f99d1f8d14a2335bfe6cc2b432 463 PANTHER PTHR11699:SF65 5 460 2.1E-223 T 13-09-2016 THL1_RS12555 0eede2f99d1f8d14a2335bfe6cc2b432 463 Gene3D G3DSA:3.40.605.10 3 244 3.0E-66 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS12555 0eede2f99d1f8d14a2335bfe6cc2b432 463 Pfam PF00171 Aldehyde dehydrogenase family 5 456 5.3E-123 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS12555 0eede2f99d1f8d14a2335bfe6cc2b432 463 PANTHER PTHR11699 5 460 2.1E-223 T 13-09-2016 THL1_RS12555 0eede2f99d1f8d14a2335bfe6cc2b432 463 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 258 269 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS03965 032e7c88199a57939b88767390e1a569 257 Pfam PF06251 Capsule biosynthesis GfcC 34 249 1.6E-31 T 13-09-2016 IPR010425 Domain of unknown function DUF1017 THL1_RS18635 44158ec592db21dc6c88e5bda81d4fd4 271 Gene3D G3DSA:3.30.470.10 4 104 2.7E-28 T 13-09-2016 THL1_RS18635 44158ec592db21dc6c88e5bda81d4fd4 271 PANTHER PTHR11825:SF55 2 267 1.5E-69 T 13-09-2016 THL1_RS18635 44158ec592db21dc6c88e5bda81d4fd4 271 TIGRFAM TIGR03461 pabC_Proteo: aminodeoxychorismate lyase 4 263 2.5E-87 T 13-09-2016 IPR017824 Aminodeoxychorismate lyase, class IV GO:0008696|GO:0030170|GO:0046656 KEGG: 00790+4.1.3.38|MetaCyc: PWY-6543|UniPathway: UPA00077 THL1_RS18635 44158ec592db21dc6c88e5bda81d4fd4 271 PANTHER PTHR11825 2 267 1.5E-69 T 13-09-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 THL1_RS18635 44158ec592db21dc6c88e5bda81d4fd4 271 Pfam PF01063 Amino-transferase class IV 25 247 1.2E-48 T 13-09-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 THL1_RS18635 44158ec592db21dc6c88e5bda81d4fd4 271 Gene3D G3DSA:3.20.10.10 124 262 1.6E-43 T 13-09-2016 THL1_RS18635 44158ec592db21dc6c88e5bda81d4fd4 271 SUPERFAMILY SSF56752 3 262 5.36E-73 T 13-09-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 THL1_RS19235 47f0f53eeb548753bcc131f4ea451258 442 Pfam PF00849 RNA pseudouridylate synthase 75 206 1.2E-14 T 13-09-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS19235 47f0f53eeb548753bcc131f4ea451258 442 Gene3D G3DSA:3.10.290.10 10 69 6.4E-19 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS19235 47f0f53eeb548753bcc131f4ea451258 442 Pfam PF01479 S4 domain 12 56 3.3E-12 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS19235 47f0f53eeb548753bcc131f4ea451258 442 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 79 241 1.2E-54 T 13-09-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 THL1_RS19235 47f0f53eeb548753bcc131f4ea451258 442 SMART SM00363 11 68 1.3E-9 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS19235 47f0f53eeb548753bcc131f4ea451258 442 SUPERFAMILY SSF55120 74 244 5.76E-42 T 13-09-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS19235 47f0f53eeb548753bcc131f4ea451258 442 SUPERFAMILY SSF55174 13 104 3.09E-18 T 13-09-2016 THL1_RS19235 47f0f53eeb548753bcc131f4ea451258 442 PANTHER PTHR21600:SF2 9 315 1.4E-93 T 13-09-2016 THL1_RS19235 47f0f53eeb548753bcc131f4ea451258 442 PANTHER PTHR21600 9 315 1.4E-93 T 13-09-2016 THL1_RS19235 47f0f53eeb548753bcc131f4ea451258 442 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 113 127 - T 13-09-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 THL1_RS25200 e48736cb5fc04b2caabcb8d89a7eb3e6 186 Pfam PF13590 Domain of unknown function (DUF4136) 23 185 7.9E-31 T 13-09-2016 IPR025411 Domain of unknown function DUF4136 THL1_RS08735 b06673d2d39b9dba33948032b47b5f25 69 PIRSF PIRSF002599 1 69 3.5E-23 T 13-09-2016 IPR012156 Cold shock, CspA GO:0003676 THL1_RS08735 b06673d2d39b9dba33948032b47b5f25 69 SUPERFAMILY SSF50249 2 68 2.42E-24 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS08735 b06673d2d39b9dba33948032b47b5f25 69 Gene3D G3DSA:2.40.50.140 5 68 4.8E-30 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS08735 b06673d2d39b9dba33948032b47b5f25 69 PRINTS PR00050 Cold shock protein signature 42 60 1.7E-16 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS08735 b06673d2d39b9dba33948032b47b5f25 69 PRINTS PR00050 Cold shock protein signature 7 22 1.7E-16 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS08735 b06673d2d39b9dba33948032b47b5f25 69 PRINTS PR00050 Cold shock protein signature 27 36 1.7E-16 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS08735 b06673d2d39b9dba33948032b47b5f25 69 PANTHER PTHR11544 1 69 5.3E-38 T 13-09-2016 THL1_RS08735 b06673d2d39b9dba33948032b47b5f25 69 Pfam PF00313 'Cold-shock' DNA-binding domain 6 68 1.4E-27 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS08735 b06673d2d39b9dba33948032b47b5f25 69 PANTHER PTHR11544:SF63 1 69 5.3E-38 T 13-09-2016 THL1_RS08735 b06673d2d39b9dba33948032b47b5f25 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 36 - T 13-09-2016 IPR019844 Cold-shock conserved site THL1_RS08735 b06673d2d39b9dba33948032b47b5f25 69 SMART SM00357 6 69 9.0E-29 T 13-09-2016 IPR011129 Cold shock protein GO:0003676 THL1_RS27020 b814615d879969d0182a076b0f5a73ef 635 PANTHER PTHR11712:SF272 179 609 9.3E-42 T 13-09-2016 THL1_RS27020 b814615d879969d0182a076b0f5a73ef 635 Gene3D G3DSA:3.40.47.10 389 542 1.0E-20 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS27020 b814615d879969d0182a076b0f5a73ef 635 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 186 371 1.3E-12 T 13-09-2016 IPR014030 Beta-ketoacyl synthase, N-terminal THL1_RS27020 b814615d879969d0182a076b0f5a73ef 635 PANTHER PTHR11712 179 609 9.3E-42 T 13-09-2016 THL1_RS27020 b814615d879969d0182a076b0f5a73ef 635 Gene3D G3DSA:3.40.47.10 159 384 6.5E-23 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS27020 b814615d879969d0182a076b0f5a73ef 635 SUPERFAMILY SSF53901 344 545 4.03E-29 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS27020 b814615d879969d0182a076b0f5a73ef 635 SUPERFAMILY SSF53901 166 380 5.07E-29 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS27020 b814615d879969d0182a076b0f5a73ef 635 SMART SM00825 Beta-ketoacyl synthase 144 550 0.0053 T 13-09-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain THL1_RS27020 b814615d879969d0182a076b0f5a73ef 635 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 382 496 2.4E-10 T 13-09-2016 IPR014031 Beta-ketoacyl synthase, C-terminal THL1_RS23740 78bd5ab5dd95eb84dd295d617360d71b 560 SUPERFAMILY SSF56801 29 547 2.22E-132 T 13-09-2016 THL1_RS23740 78bd5ab5dd95eb84dd295d617360d71b 560 Gene3D G3DSA:3.40.50.980 33 190 2.2E-30 T 13-09-2016 THL1_RS23740 78bd5ab5dd95eb84dd295d617360d71b 560 Gene3D G3DSA:3.40.50.980 191 349 1.4E-37 T 13-09-2016 THL1_RS23740 78bd5ab5dd95eb84dd295d617360d71b 560 Gene3D G3DSA:3.30.300.30 442 543 7.4E-27 T 13-09-2016 THL1_RS23740 78bd5ab5dd95eb84dd295d617360d71b 560 Pfam PF00501 AMP-binding enzyme 33 447 4.2E-89 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS23740 78bd5ab5dd95eb84dd295d617360d71b 560 Gene3D G3DSA:2.30.38.10 365 441 1.2E-19 T 13-09-2016 THL1_RS23740 78bd5ab5dd95eb84dd295d617360d71b 560 PANTHER PTHR24096:SF136 13 546 0.0 T 13-09-2016 THL1_RS23740 78bd5ab5dd95eb84dd295d617360d71b 560 PANTHER PTHR24096 13 546 0.0 T 13-09-2016 THL1_RS23740 78bd5ab5dd95eb84dd295d617360d71b 560 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 536 1.2E-19 T 13-09-2016 IPR025110 AMP-binding enzyme C-terminal domain THL1_RS02635 d504e3193fa6df84de5a2e33eecc06ee 255 Gene3D G3DSA:1.10.287.110 183 249 2.5E-9 T 13-09-2016 IPR001623 DnaJ domain THL1_RS02635 d504e3193fa6df84de5a2e33eecc06ee 255 SMART SM00271 188 253 1.7E-6 T 13-09-2016 IPR001623 DnaJ domain THL1_RS02635 d504e3193fa6df84de5a2e33eecc06ee 255 PRINTS PR00625 DnaJ domain signature 233 253 5.1E-5 T 13-09-2016 IPR001623 DnaJ domain THL1_RS02635 d504e3193fa6df84de5a2e33eecc06ee 255 PRINTS PR00625 DnaJ domain signature 191 209 5.1E-5 T 13-09-2016 IPR001623 DnaJ domain THL1_RS02635 d504e3193fa6df84de5a2e33eecc06ee 255 PRINTS PR00625 DnaJ domain signature 209 224 5.1E-5 T 13-09-2016 IPR001623 DnaJ domain THL1_RS02635 d504e3193fa6df84de5a2e33eecc06ee 255 Pfam PF05099 Tellurite resistance protein TerB 49 169 2.1E-15 T 13-09-2016 IPR007791 Co-chaperone DjlA, N-terminal THL1_RS02635 d504e3193fa6df84de5a2e33eecc06ee 255 Gene3D G3DSA:1.10.3680.10 21 169 5.2E-18 T 13-09-2016 IPR029024 TerB-like THL1_RS02635 d504e3193fa6df84de5a2e33eecc06ee 255 SUPERFAMILY SSF46565 193 249 2.24E-10 T 13-09-2016 IPR001623 DnaJ domain THL1_RS02635 d504e3193fa6df84de5a2e33eecc06ee 255 SUPERFAMILY SSF158682 48 171 1.2E-18 T 13-09-2016 IPR029024 TerB-like THL1_RS25670 957a402e61aaf366d3363d96b77c34f2 313 Gene3D G3DSA:3.40.50.720 135 293 1.6E-52 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS25670 957a402e61aaf366d3363d96b77c34f2 313 PANTHER PTHR13812:SF19 1 311 1.6E-94 T 13-09-2016 THL1_RS25670 957a402e61aaf366d3363d96b77c34f2 313 PIRSF PIRSF001439 2 312 6.6E-73 T 13-09-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin THL1_RS25670 957a402e61aaf366d3363d96b77c34f2 313 Gene3D G3DSA:3.30.1780.10 4 134 9.5E-40 T 13-09-2016 IPR023401 Ornithine cyclodeaminase, N-terminal THL1_RS25670 957a402e61aaf366d3363d96b77c34f2 313 PANTHER PTHR13812 1 311 1.6E-94 T 13-09-2016 THL1_RS25670 957a402e61aaf366d3363d96b77c34f2 313 SUPERFAMILY SSF51735 2 309 3.38E-87 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS25670 957a402e61aaf366d3363d96b77c34f2 313 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 12 309 1.4E-59 T 13-09-2016 IPR003462 Ornithine cyclodeaminase/mu-crystallin THL1_RS03170 924691d0c7e96ce2dd3761eb5e8d1e19 194 Pfam PF13328 HD domain 14 158 8.7E-27 T 13-09-2016 IPR003607 HD/PDEase domain THL1_RS03170 924691d0c7e96ce2dd3761eb5e8d1e19 194 PANTHER PTHR21262:SF16 10 170 3.9E-50 T 13-09-2016 THL1_RS03170 924691d0c7e96ce2dd3761eb5e8d1e19 194 SUPERFAMILY SSF109604 5 169 7.53E-33 T 13-09-2016 THL1_RS03170 924691d0c7e96ce2dd3761eb5e8d1e19 194 SMART SM00471 30 143 5.2E-4 T 13-09-2016 IPR003607 HD/PDEase domain THL1_RS03170 924691d0c7e96ce2dd3761eb5e8d1e19 194 PANTHER PTHR21262 10 170 3.9E-50 T 13-09-2016 THL1_RS23770 b9b59d8926da444584464198c22e46ee 320 PANTHER PTHR10996:SF91 14 317 1.2E-100 T 13-09-2016 THL1_RS23770 b9b59d8926da444584464198c22e46ee 320 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 289 1.4E-52 T 13-09-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 THL1_RS23770 b9b59d8926da444584464198c22e46ee 320 SUPERFAMILY SSF52283 16 140 5.86E-28 T 13-09-2016 THL1_RS23770 b9b59d8926da444584464198c22e46ee 320 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 226 242 - T 13-09-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site THL1_RS23770 b9b59d8926da444584464198c22e46ee 320 SUPERFAMILY SSF51735 105 290 9.81E-52 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23770 b9b59d8926da444584464198c22e46ee 320 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 20 315 7.3E-24 T 13-09-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 THL1_RS23770 b9b59d8926da444584464198c22e46ee 320 Gene3D G3DSA:3.40.50.720 115 290 3.8E-58 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23770 b9b59d8926da444584464198c22e46ee 320 PANTHER PTHR10996 14 317 1.2E-100 T 13-09-2016 THL1_RS23770 b9b59d8926da444584464198c22e46ee 320 Gene3D G3DSA:3.40.50.720 16 114 4.3E-26 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS22060 cdb516f35582248162629b77d0a1fc5d 477 SUPERFAMILY SSF48452 287 450 2.38E-15 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS22060 cdb516f35582248162629b77d0a1fc5d 477 Gene3D G3DSA:1.25.40.10 284 448 3.2E-16 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS22060 cdb516f35582248162629b77d0a1fc5d 477 Pfam PF14559 Tetratricopeptide repeat 284 336 4.2E-9 T 13-09-2016 THL1_RS22060 cdb516f35582248162629b77d0a1fc5d 477 Pfam PF14559 Tetratricopeptide repeat 346 408 2.5E-8 T 13-09-2016 THL1_RS22060 cdb516f35582248162629b77d0a1fc5d 477 Hamap MF_00997 Beta-barrel assembly-enhancing protease [bepA]. 1 473 32.272 T 13-09-2016 IPR030873 Beta-barrel assembly-enhancing protease GO:0006508|GO:0008237|GO:0016020|GO:0061077 THL1_RS22060 cdb516f35582248162629b77d0a1fc5d 477 PANTHER PTHR22726:SF10 1 345 2.4E-120 T 13-09-2016 THL1_RS22060 cdb516f35582248162629b77d0a1fc5d 477 Pfam PF01435 Peptidase family M48 63 250 2.0E-31 T 13-09-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 THL1_RS22060 cdb516f35582248162629b77d0a1fc5d 477 PANTHER PTHR22726 1 345 2.4E-120 T 13-09-2016 THL1_RS22060 cdb516f35582248162629b77d0a1fc5d 477 Gene3D G3DSA:3.30.2010.10 58 142 5.2E-18 T 13-09-2016 THL1_RS11985 fbb11d601f6e0b10b103ccb2c4fcc921 206 PANTHER PTHR30363 5 175 1.9E-14 T 13-09-2016 THL1_RS11985 fbb11d601f6e0b10b103ccb2c4fcc921 206 Pfam PF12802 MarR family 4 59 9.9E-7 T 13-09-2016 THL1_RS11985 fbb11d601f6e0b10b103ccb2c4fcc921 206 SUPERFAMILY SSF46785 7 181 1.95E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11985 fbb11d601f6e0b10b103ccb2c4fcc921 206 Gene3D G3DSA:1.10.10.10 4 111 1.6E-13 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11985 fbb11d601f6e0b10b103ccb2c4fcc921 206 PANTHER PTHR30363:SF17 5 175 1.9E-14 T 13-09-2016 THL1_RS28235 45d4091ec8713a2b7c6d558b2fbb3b2e 480 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 9 183 2.6E-54 T 13-09-2016 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS28235 45d4091ec8713a2b7c6d558b2fbb3b2e 480 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 185 479 8.6E-122 T 13-09-2016 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS28235 45d4091ec8713a2b7c6d558b2fbb3b2e 480 SUPERFAMILY SSF55347 173 479 5.56E-117 T 13-09-2016 THL1_RS28235 45d4091ec8713a2b7c6d558b2fbb3b2e 480 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 163 191 1.7E-48 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS28235 45d4091ec8713a2b7c6d558b2fbb3b2e 480 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 139 152 1.7E-48 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS28235 45d4091ec8713a2b7c6d558b2fbb3b2e 480 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 233 249 1.7E-48 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS28235 45d4091ec8713a2b7c6d558b2fbb3b2e 480 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 215 232 1.7E-48 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS28235 45d4091ec8713a2b7c6d558b2fbb3b2e 480 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 324 350 1.7E-48 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS28235 45d4091ec8713a2b7c6d558b2fbb3b2e 480 PANTHER PTHR23429 2 480 2.6E-215 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS28235 45d4091ec8713a2b7c6d558b2fbb3b2e 480 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 4 480 84.018 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS28235 45d4091ec8713a2b7c6d558b2fbb3b2e 480 PIRSF PIRSF000110 1 480 6.3E-175 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS28235 45d4091ec8713a2b7c6d558b2fbb3b2e 480 Gene3D G3DSA:3.40.50.720 3 182 1.2E-56 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS28235 45d4091ec8713a2b7c6d558b2fbb3b2e 480 PANTHER PTHR23429:SF0 2 480 2.6E-215 T 13-09-2016 THL1_RS28235 45d4091ec8713a2b7c6d558b2fbb3b2e 480 Gene3D G3DSA:3.30.360.10 183 479 5.1E-127 T 13-09-2016 THL1_RS28235 45d4091ec8713a2b7c6d558b2fbb3b2e 480 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 4 479 1.0E-177 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS28235 45d4091ec8713a2b7c6d558b2fbb3b2e 480 SUPERFAMILY SSF51735 3 186 1.57E-53 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS28235 45d4091ec8713a2b7c6d558b2fbb3b2e 480 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 173 179 - T 13-09-2016 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS10325 d343f8bc140417b4af9048e22c265504 319 Gene3D G3DSA:1.10.8.300 201 315 6.9E-41 T 13-09-2016 THL1_RS10325 d343f8bc140417b4af9048e22c265504 319 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 37 167 1.8E-63 T 13-09-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 THL1_RS10325 d343f8bc140417b4af9048e22c265504 319 PIRSF PIRSF002849 1 319 3.6E-127 T 13-09-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted THL1_RS10325 d343f8bc140417b4af9048e22c265504 319 Gene3D G3DSA:3.40.50.300 19 183 5.2E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10325 d343f8bc140417b4af9048e22c265504 319 PANTHER PTHR11603:SF148 1 318 3.1E-150 T 13-09-2016 THL1_RS10325 d343f8bc140417b4af9048e22c265504 319 PANTHER PTHR11603 1 318 3.1E-150 T 13-09-2016 THL1_RS10325 d343f8bc140417b4af9048e22c265504 319 SUPERFAMILY SSF52540 4 291 3.36E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS23590 53f961c1c323d1a15a3ee825bdfc1786 315 PANTHER PTHR30204:SF19 11 247 2.8E-34 T 13-09-2016 THL1_RS23590 53f961c1c323d1a15a3ee825bdfc1786 315 PANTHER PTHR30204 11 247 2.8E-34 T 13-09-2016 THL1_RS23590 53f961c1c323d1a15a3ee825bdfc1786 315 SMART SM00422 19 88 4.8E-22 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS23590 53f961c1c323d1a15a3ee825bdfc1786 315 Gene3D G3DSA:1.10.1660.10 20 100 7.4E-19 T 13-09-2016 THL1_RS23590 53f961c1c323d1a15a3ee825bdfc1786 315 SUPERFAMILY SSF46955 19 94 1.6E-18 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS23590 53f961c1c323d1a15a3ee825bdfc1786 315 Pfam PF13411 MerR HTH family regulatory protein 20 86 6.9E-16 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS07725 3b01a695b2c3a76a12df7b4f3371687b 464 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 202 395 5.1E-11 T 13-09-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 THL1_RS07725 3b01a695b2c3a76a12df7b4f3371687b 464 TIGRFAM TIGR03228 anthran_1_2_A: anthranilate 1,2-dioxygenase, large subunit 15 452 4.0E-293 T 13-09-2016 IPR017638 Anthranilate 1,2-dioxygenase, large subunit KEGG: 00627+1.14.12.1|MetaCyc: PWY-2421|MetaCyc: PWY-5648|MetaCyc: PWY-6079|UniPathway: UPA01016 THL1_RS07725 3b01a695b2c3a76a12df7b4f3371687b 464 Pfam PF00355 Rieske [2Fe-2S] domain 52 136 2.3E-22 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS07725 3b01a695b2c3a76a12df7b4f3371687b 464 Gene3D G3DSA:3.90.380.10 156 455 1.2E-71 T 13-09-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 THL1_RS07725 3b01a695b2c3a76a12df7b4f3371687b 464 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 95 118 - T 13-09-2016 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 THL1_RS07725 3b01a695b2c3a76a12df7b4f3371687b 464 SUPERFAMILY SSF55961 171 455 5.02E-58 T 13-09-2016 THL1_RS07725 3b01a695b2c3a76a12df7b4f3371687b 464 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 67 82 1.7E-34 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS07725 3b01a695b2c3a76a12df7b4f3371687b 464 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 194 216 1.7E-34 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS07725 3b01a695b2c3a76a12df7b4f3371687b 464 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 109 129 1.7E-34 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS07725 3b01a695b2c3a76a12df7b4f3371687b 464 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 151 177 1.7E-34 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS07725 3b01a695b2c3a76a12df7b4f3371687b 464 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 88 108 1.7E-34 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS07725 3b01a695b2c3a76a12df7b4f3371687b 464 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 37 62 1.7E-34 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS07725 3b01a695b2c3a76a12df7b4f3371687b 464 Gene3D G3DSA:2.102.10.10 52 155 7.4E-24 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS07725 3b01a695b2c3a76a12df7b4f3371687b 464 PANTHER PTHR21266:SF30 1 383 1.5E-117 T 13-09-2016 THL1_RS07725 3b01a695b2c3a76a12df7b4f3371687b 464 PANTHER PTHR21266 1 383 1.5E-117 T 13-09-2016 THL1_RS07725 3b01a695b2c3a76a12df7b4f3371687b 464 SUPERFAMILY SSF50022 21 165 3.4E-46 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS25310 5f2b671ac7dfb55a1b7f6049bb91dcce 251 Gene3D G3DSA:3.40.50.2300 5 154 2.9E-30 T 13-09-2016 THL1_RS25310 5f2b671ac7dfb55a1b7f6049bb91dcce 251 Gene3D G3DSA:1.10.10.10 178 239 3.1E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS25310 5f2b671ac7dfb55a1b7f6049bb91dcce 251 SUPERFAMILY SSF52172 5 159 4.7E-32 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS25310 5f2b671ac7dfb55a1b7f6049bb91dcce 251 SUPERFAMILY SSF46894 172 239 1.26E-15 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS25310 5f2b671ac7dfb55a1b7f6049bb91dcce 251 SMART SM00448 6 121 3.0E-23 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS25310 5f2b671ac7dfb55a1b7f6049bb91dcce 251 Pfam PF00072 Response regulator receiver domain 9 121 3.7E-20 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS25310 5f2b671ac7dfb55a1b7f6049bb91dcce 251 SMART SM00421 182 239 5.4E-16 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS25310 5f2b671ac7dfb55a1b7f6049bb91dcce 251 Pfam PF00196 Bacterial regulatory proteins, luxR family 184 237 1.2E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS25310 5f2b671ac7dfb55a1b7f6049bb91dcce 251 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 199 5.3E-7 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS25310 5f2b671ac7dfb55a1b7f6049bb91dcce 251 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 215 227 5.3E-7 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS25310 5f2b671ac7dfb55a1b7f6049bb91dcce 251 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 199 215 5.3E-7 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS25310 5f2b671ac7dfb55a1b7f6049bb91dcce 251 PANTHER PTHR26402 164 237 2.0E-41 T 13-09-2016 THL1_RS25310 5f2b671ac7dfb55a1b7f6049bb91dcce 251 PANTHER PTHR26402 6 139 2.0E-41 T 13-09-2016 THL1_RS19195 d2f0ea4541841ba1b0f39d7634b442ff 361 SUPERFAMILY SSF53383 4 358 1.2E-115 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS19195 d2f0ea4541841ba1b0f39d7634b442ff 361 PIRSF PIRSF000525 1 361 5.5E-149 T 13-09-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 THL1_RS19195 d2f0ea4541841ba1b0f39d7634b442ff 361 Gene3D G3DSA:3.90.1150.10 259 359 2.6E-41 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS19195 d2f0ea4541841ba1b0f39d7634b442ff 361 PANTHER PTHR21152 2 361 1.4E-188 T 13-09-2016 THL1_RS19195 d2f0ea4541841ba1b0f39d7634b442ff 361 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 3 360 51.413 T 13-09-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 THL1_RS19195 d2f0ea4541841ba1b0f39d7634b442ff 361 Pfam PF00266 Aminotransferase class-V 6 349 1.8E-50 T 13-09-2016 IPR000192 Aminotransferase class V domain THL1_RS19195 d2f0ea4541841ba1b0f39d7634b442ff 361 Gene3D G3DSA:3.40.640.10 18 258 2.9E-107 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS19195 d2f0ea4541841ba1b0f39d7634b442ff 361 PANTHER PTHR21152:SF1 2 361 1.4E-188 T 13-09-2016 THL1_RS19195 d2f0ea4541841ba1b0f39d7634b442ff 361 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 6 359 8.5E-163 T 13-09-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 THL1_RS22495 5a668f008316be52e40a2089ab2b07dc 225 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 21 220 4.0E-64 T 13-09-2016 THL1_RS22495 5a668f008316be52e40a2089ab2b07dc 225 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 16 225 39.114 T 13-09-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 THL1_RS22495 5a668f008316be52e40a2089ab2b07dc 225 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 16 222 1.3E-69 T 13-09-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 THL1_RS22495 5a668f008316be52e40a2089ab2b07dc 225 SUPERFAMILY SSF53335 17 222 9.94E-45 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS22495 5a668f008316be52e40a2089ab2b07dc 225 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 146 161 - T 13-09-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 THL1_RS22495 5a668f008316be52e40a2089ab2b07dc 225 Gene3D G3DSA:3.40.50.150 30 221 7.7E-60 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS22495 5a668f008316be52e40a2089ab2b07dc 225 PANTHER PTHR11579 10 219 7.5E-89 T 13-09-2016 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 THL1_RS27660 4c5601898f13b43ed82bcc53925c7c82 78 SUPERFAMILY SSF48452 3 62 7.91E-7 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS27660 4c5601898f13b43ed82bcc53925c7c82 78 Gene3D G3DSA:1.25.40.10 2 59 1.2E-7 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS10795 286e18fc08ef1acb08eb0b18fa7d184f 254 Gene3D G3DSA:3.90.550.10 5 252 2.5E-82 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS10795 286e18fc08ef1acb08eb0b18fa7d184f 254 PANTHER PTHR21485:SF4 5 252 1.4E-114 T 13-09-2016 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 THL1_RS10795 286e18fc08ef1acb08eb0b18fa7d184f 254 PANTHER PTHR21485 5 252 1.4E-114 T 13-09-2016 THL1_RS10795 286e18fc08ef1acb08eb0b18fa7d184f 254 SUPERFAMILY SSF53448 5 252 1.55E-62 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS10795 286e18fc08ef1acb08eb0b18fa7d184f 254 Pfam PF02348 Cytidylyltransferase 7 226 7.8E-57 T 13-09-2016 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 THL1_RS10795 286e18fc08ef1acb08eb0b18fa7d184f 254 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 4 246 6.0E-95 T 13-09-2016 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 THL1_RS10795 286e18fc08ef1acb08eb0b18fa7d184f 254 Hamap MF_00057 3-deoxy-manno-octulosonate cytidylyltransferase [kdsB]. 3 253 44.795 T 13-09-2016 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|UniPathway: UPA00030|UniPathway: UPA00358 THL1_RS07995 0d07a90506d8d9baff0746090040a5ac 109 TIGRFAM TIGR02448 TIGR02448: conserverd hypothetical protein 1 105 4.3E-26 T 13-09-2016 IPR012661 Conserved hypothetical protein CHP02448 THL1_RS07995 0d07a90506d8d9baff0746090040a5ac 109 Pfam PF09498 Protein of unknown function (DUF2388) 35 105 2.8E-29 T 13-09-2016 IPR012661 Conserved hypothetical protein CHP02448 THL1_RS21995 adefe2685f91dea203b2f4a8e7dab617 512 Pfam PF00589 Phage integrase family 324 482 4.4E-11 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS21995 adefe2685f91dea203b2f4a8e7dab617 512 Gene3D G3DSA:1.10.443.10 323 490 5.7E-21 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS21995 adefe2685f91dea203b2f4a8e7dab617 512 SUPERFAMILY SSF56349 214 499 1.27E-27 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS04970 8a851b46da83b3d79719afc4fb013453 379 PANTHER PTHR24559 138 323 4.4E-21 T 13-09-2016 THL1_RS04970 8a851b46da83b3d79719afc4fb013453 379 SUPERFAMILY SSF46689 8 116 1.74E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS04970 8a851b46da83b3d79719afc4fb013453 379 Pfam PF13565 Homeodomain-like domain 39 112 1.0E-11 T 13-09-2016 THL1_RS04970 8a851b46da83b3d79719afc4fb013453 379 Gene3D G3DSA:1.10.10.60 11 57 2.5E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS04970 8a851b46da83b3d79719afc4fb013453 379 Gene3D G3DSA:3.30.420.10 132 296 5.9E-38 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS04970 8a851b46da83b3d79719afc4fb013453 379 SUPERFAMILY SSF53098 138 302 2.28E-35 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS04970 8a851b46da83b3d79719afc4fb013453 379 Pfam PF00665 Integrase core domain 138 259 1.7E-24 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS05115 8a851b46da83b3d79719afc4fb013453 379 PANTHER PTHR24559 138 323 4.4E-21 T 13-09-2016 THL1_RS05115 8a851b46da83b3d79719afc4fb013453 379 SUPERFAMILY SSF46689 8 116 1.74E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS05115 8a851b46da83b3d79719afc4fb013453 379 Pfam PF13565 Homeodomain-like domain 39 112 1.0E-11 T 13-09-2016 THL1_RS05115 8a851b46da83b3d79719afc4fb013453 379 Gene3D G3DSA:1.10.10.60 11 57 2.5E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS05115 8a851b46da83b3d79719afc4fb013453 379 Gene3D G3DSA:3.30.420.10 132 296 5.9E-38 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS05115 8a851b46da83b3d79719afc4fb013453 379 SUPERFAMILY SSF53098 138 302 2.28E-35 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS05115 8a851b46da83b3d79719afc4fb013453 379 Pfam PF00665 Integrase core domain 138 259 1.7E-24 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS05120 f20f24bbaadbd37fd9d4bdd759a18486 182 Gene3D G3DSA:3.40.80.10 7 180 1.9E-68 T 13-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 THL1_RS05120 f20f24bbaadbd37fd9d4bdd759a18486 182 PANTHER PTHR30417:SF4 8 181 9.7E-75 T 13-09-2016 THL1_RS05120 f20f24bbaadbd37fd9d4bdd759a18486 182 SMART SM00644 18 168 6.7E-53 T 13-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 THL1_RS05120 f20f24bbaadbd37fd9d4bdd759a18486 182 PANTHER PTHR30417 8 181 9.7E-75 T 13-09-2016 THL1_RS05120 f20f24bbaadbd37fd9d4bdd759a18486 182 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 28 169 2.4E-19 T 13-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 THL1_RS05120 f20f24bbaadbd37fd9d4bdd759a18486 182 SUPERFAMILY SSF55846 6 180 3.27E-64 T 13-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 THL1_RS26740 d399062554aace7a5cf19af6cd166da3 256 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 256 49.007 T 13-09-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UniPathway: UPA00031 THL1_RS26740 d399062554aace7a5cf19af6cd166da3 256 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 256 3.9E-116 T 13-09-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UniPathway: UPA00031 THL1_RS26740 d399062554aace7a5cf19af6cd166da3 256 Gene3D G3DSA:3.20.20.70 5 256 1.4E-109 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS26740 d399062554aace7a5cf19af6cd166da3 256 Pfam PF00977 Histidine biosynthesis protein 6 240 3.8E-92 T 13-09-2016 IPR006062 Histidine biosynthesis GO:0000105 THL1_RS26740 d399062554aace7a5cf19af6cd166da3 256 SUPERFAMILY SSF51366 3 256 2.59E-84 T 13-09-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 THL1_RS26740 d399062554aace7a5cf19af6cd166da3 256 PANTHER PTHR21235:SF2 3 256 2.2E-126 T 13-09-2016 THL1_RS26740 d399062554aace7a5cf19af6cd166da3 256 PANTHER PTHR21235 3 256 2.2E-126 T 13-09-2016 THL1_RS04450 96502791912dedc561ac191836b52493 465 SUPERFAMILY SSF51556 63 381 1.45E-88 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS04450 96502791912dedc561ac191836b52493 465 SUPERFAMILY SSF51338 21 63 4.64E-20 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS04450 96502791912dedc561ac191836b52493 465 SUPERFAMILY SSF51338 383 457 4.64E-20 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS04450 96502791912dedc561ac191836b52493 465 PANTHER PTHR11271:SF37 4 459 1.4E-116 T 13-09-2016 THL1_RS04450 96502791912dedc561ac191836b52493 465 Pfam PF01979 Amidohydrolase family 60 416 9.5E-50 T 13-09-2016 IPR006680 Amidohydrolase-related GO:0016787 THL1_RS04450 96502791912dedc561ac191836b52493 465 Gene3D G3DSA:2.30.40.10 5 71 1.2E-16 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS04450 96502791912dedc561ac191836b52493 465 Gene3D G3DSA:3.20.20.140 72 402 1.2E-94 T 13-09-2016 THL1_RS04450 96502791912dedc561ac191836b52493 465 PANTHER PTHR11271 4 459 1.4E-116 T 13-09-2016 THL1_RS15805 9a63c12300bb31ec8ddd0c1aac27466c 446 PANTHER PTHR11958 9 429 1.3E-208 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS15805 9a63c12300bb31ec8ddd0c1aac27466c 446 SUPERFAMILY SSF118215 9 403 2.09E-113 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS15805 9a63c12300bb31ec8ddd0c1aac27466c 446 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 2 430 36.878 T 13-09-2016 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 THL1_RS15805 9a63c12300bb31ec8ddd0c1aac27466c 446 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 297 320 - T 13-09-2016 IPR018107 Sodium:dicarboxylate symporter, conserved site Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS15805 9a63c12300bb31ec8ddd0c1aac27466c 446 Gene3D G3DSA:1.10.3860.10 8 409 2.4E-111 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS15805 9a63c12300bb31ec8ddd0c1aac27466c 446 PRINTS PR00173 Glutamate-aspartate symporter signature 147 169 2.4E-29 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS15805 9a63c12300bb31ec8ddd0c1aac27466c 446 PRINTS PR00173 Glutamate-aspartate symporter signature 357 377 2.4E-29 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS15805 9a63c12300bb31ec8ddd0c1aac27466c 446 PRINTS PR00173 Glutamate-aspartate symporter signature 44 64 2.4E-29 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS15805 9a63c12300bb31ec8ddd0c1aac27466c 446 PRINTS PR00173 Glutamate-aspartate symporter signature 3 23 2.4E-29 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS15805 9a63c12300bb31ec8ddd0c1aac27466c 446 PRINTS PR00173 Glutamate-aspartate symporter signature 294 320 2.4E-29 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS15805 9a63c12300bb31ec8ddd0c1aac27466c 446 PRINTS PR00173 Glutamate-aspartate symporter signature 74 99 2.4E-29 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS15805 9a63c12300bb31ec8ddd0c1aac27466c 446 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 36 51 - T 13-09-2016 IPR018107 Sodium:dicarboxylate symporter, conserved site Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS15805 9a63c12300bb31ec8ddd0c1aac27466c 446 PANTHER PTHR11958:SF49 9 429 1.3E-208 T 13-09-2016 THL1_RS15805 9a63c12300bb31ec8ddd0c1aac27466c 446 Pfam PF00375 Sodium:dicarboxylate symporter family 9 403 5.2E-106 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS04000 c50c63a224a2f48780b7806c1685675c 354 Pfam PF04230 Polysaccharide pyruvyl transferase 16 291 6.5E-24 T 13-09-2016 IPR007345 Polysaccharide pyruvyl transferase THL1_RS13120 19604ab1c213d48db5e1371171d9c763 113 Pfam PF02411 MerT mercuric transport protein 6 112 2.0E-17 T 13-09-2016 IPR003457 Mercuric transport protein MerT GO:0015097|GO:0015694|GO:0016020 THL1_RS09100 ab02bb4d199237e529979effe1eb7067 284 PANTHER PTHR11364 1 283 2.0E-89 T 13-09-2016 THL1_RS09100 ab02bb4d199237e529979effe1eb7067 284 Gene3D G3DSA:3.40.250.10 153 284 1.6E-36 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS09100 ab02bb4d199237e529979effe1eb7067 284 Gene3D G3DSA:3.40.250.10 2 152 2.5E-42 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS09100 ab02bb4d199237e529979effe1eb7067 284 PANTHER PTHR11364:SF0 1 283 2.0E-89 T 13-09-2016 THL1_RS09100 ab02bb4d199237e529979effe1eb7067 284 SMART SM00450 158 278 6.9E-11 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS09100 ab02bb4d199237e529979effe1eb7067 284 SMART SM00450 7 135 1.0E-16 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS09100 ab02bb4d199237e529979effe1eb7067 284 Pfam PF00581 Rhodanese-like domain 160 273 5.4E-11 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS09100 ab02bb4d199237e529979effe1eb7067 284 Pfam PF00581 Rhodanese-like domain 8 131 6.7E-14 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS09100 ab02bb4d199237e529979effe1eb7067 284 SUPERFAMILY SSF52821 2 155 3.14E-37 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS09100 ab02bb4d199237e529979effe1eb7067 284 ProSitePatterns PS00683 Rhodanese C-terminal signature. 262 272 - T 13-09-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 THL1_RS09100 ab02bb4d199237e529979effe1eb7067 284 SUPERFAMILY SSF52821 151 283 2.88E-32 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS04895 500edcbf816e173d802fa1a2c0b0dc14 381 Pfam PF16074 Type IV Pilus-assembly protein W 215 373 5.0E-26 T 13-09-2016 IPR032092 Type IV Pilus-assembly protein W GO:0043683 THL1_RS04895 500edcbf816e173d802fa1a2c0b0dc14 381 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 22 42 - T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS04895 500edcbf816e173d802fa1a2c0b0dc14 381 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 18 43 1.5E-8 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS04895 500edcbf816e173d802fa1a2c0b0dc14 381 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 21 44 2.9E-4 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS04435 5482920c0ab18745de3ab937ae7809b2 211 Gene3D G3DSA:3.40.50.1950 14 200 3.3E-78 T 13-09-2016 IPR003382 Flavoprotein GO:0003824 THL1_RS04435 5482920c0ab18745de3ab937ae7809b2 211 PANTHER PTHR30108 14 196 3.4E-85 T 13-09-2016 THL1_RS04435 5482920c0ab18745de3ab937ae7809b2 211 PANTHER PTHR30108:SF10 14 196 3.4E-85 T 13-09-2016 THL1_RS04435 5482920c0ab18745de3ab937ae7809b2 211 SUPERFAMILY SSF52507 14 196 3.66E-62 T 13-09-2016 IPR003382 Flavoprotein GO:0003824 THL1_RS04435 5482920c0ab18745de3ab937ae7809b2 211 Pfam PF02441 Flavoprotein 14 141 1.7E-27 T 13-09-2016 IPR003382 Flavoprotein GO:0003824 THL1_RS04435 5482920c0ab18745de3ab937ae7809b2 211 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 13 196 36.649 T 13-09-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 THL1_RS04435 5482920c0ab18745de3ab937ae7809b2 211 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 14 194 7.4E-72 T 13-09-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 THL1_RS00705 57254e7387146bcef22828675667feb9 332 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 148 156 - T 13-09-2016 IPR000957 Sulphate/thiosulphate-binding, conserved site GO:0008271|GO:0008272|GO:0030288 THL1_RS00705 57254e7387146bcef22828675667feb9 332 ProSitePatterns PS00401 Prokaryotic sulfate-binding proteins signature 1. 50 62 - T 13-09-2016 IPR000957 Sulphate/thiosulphate-binding, conserved site GO:0008271|GO:0008272|GO:0030288 THL1_RS00705 57254e7387146bcef22828675667feb9 332 PANTHER PTHR30368:SF2 3 332 1.9E-186 T 13-09-2016 THL1_RS00705 57254e7387146bcef22828675667feb9 332 PANTHER PTHR30368 3 332 1.9E-186 T 13-09-2016 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 THL1_RS00705 57254e7387146bcef22828675667feb9 332 Pfam PF13531 Bacterial extracellular solute-binding protein 31 282 4.0E-46 T 13-09-2016 THL1_RS00705 57254e7387146bcef22828675667feb9 332 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 21 328 2.8E-140 T 13-09-2016 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 THL1_RS00705 57254e7387146bcef22828675667feb9 332 SUPERFAMILY SSF53850 22 330 1.12E-87 T 13-09-2016 THL1_RS00705 57254e7387146bcef22828675667feb9 332 Gene3D G3DSA:3.40.190.10 24 170 7.4E-52 T 13-09-2016 THL1_RS00705 57254e7387146bcef22828675667feb9 332 Gene3D G3DSA:3.40.190.10 174 297 1.8E-29 T 13-09-2016 THL1_RS19665 9de217878568443d7f598264a7601287 416 PANTHER PTHR30244:SF5 328 416 1.6E-74 T 13-09-2016 THL1_RS19665 9de217878568443d7f598264a7601287 416 PANTHER PTHR30244:SF5 232 306 1.6E-74 T 13-09-2016 THL1_RS19665 9de217878568443d7f598264a7601287 416 PANTHER PTHR30244:SF5 1 185 1.6E-74 T 13-09-2016 THL1_RS19665 9de217878568443d7f598264a7601287 416 SUPERFAMILY SSF64518 1 416 1.44E-79 T 13-09-2016 THL1_RS19665 9de217878568443d7f598264a7601287 416 PANTHER PTHR30244 328 416 1.6E-74 T 13-09-2016 THL1_RS19665 9de217878568443d7f598264a7601287 416 PANTHER PTHR30244 232 306 1.6E-74 T 13-09-2016 THL1_RS19665 9de217878568443d7f598264a7601287 416 PANTHER PTHR30244 1 185 1.6E-74 T 13-09-2016 THL1_RS19665 9de217878568443d7f598264a7601287 416 Gene3D G3DSA:1.20.1330.10 320 364 8.7E-31 T 13-09-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 THL1_RS19665 9de217878568443d7f598264a7601287 416 Gene3D G3DSA:1.20.1330.10 53 168 8.7E-31 T 13-09-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 THL1_RS19665 9de217878568443d7f598264a7601287 416 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 413 2.7E-93 T 13-09-2016 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 THL1_RS19665 9de217878568443d7f598264a7601287 416 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 1.4E-22 T 13-09-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 56 71 - T 13-09-2016 IPR031157 Tr-type G domain, conserved site THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 Gene3D G3DSA:3.30.70.870 392 461 2.3E-15 T 13-09-2016 THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 SUPERFAMILY SSF50447 259 390 9.06E-30 T 13-09-2016 IPR009000 Translation protein, beta-barrel domain THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 146 1.9E-16 T 13-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 6 526 9.8E-263 T 13-09-2016 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 SUPERFAMILY SSF54980 390 465 5.76E-18 T 13-09-2016 IPR009022 Elongation factor G, III-V domain THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 Gene3D G3DSA:2.40.30.10 289 391 3.2E-25 T 13-09-2016 THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 Pfam PF16658 Class II release factor RF3, C-terminal domain 384 511 4.9E-46 T 13-09-2016 IPR032090 Peptide chain release factor 3, C-terminal THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 Pfam PF03144 Elongation factor Tu domain 2 311 377 5.2E-10 T 13-09-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 2 524 51.295 T 13-09-2016 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 Gene3D G3DSA:3.40.50.300 8 279 4.4E-66 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 SUPERFAMILY SSF52540 8 274 3.97E-87 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 PRINTS PR00315 GTP-binding elongation factor signature 135 144 7.6E-12 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 PRINTS PR00315 GTP-binding elongation factor signature 13 26 7.6E-12 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 PRINTS PR00315 GTP-binding elongation factor signature 83 93 7.6E-12 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 PRINTS PR00315 GTP-binding elongation factor signature 99 110 7.6E-12 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 PRINTS PR00315 GTP-binding elongation factor signature 63 71 7.6E-12 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 PANTHER PTHR23115 248 465 9.1E-241 T 13-09-2016 THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 PANTHER PTHR23115 1 182 9.1E-241 T 13-09-2016 THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 PANTHER PTHR23115:SF69 248 465 9.1E-241 T 13-09-2016 THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 PANTHER PTHR23115:SF69 1 182 9.1E-241 T 13-09-2016 THL1_RS05165 c6ab1a3672ba286b5af6dd5703e6b499 527 Pfam PF00009 Elongation factor Tu GTP binding domain 11 274 1.1E-46 T 13-09-2016 THL1_RS06740 c4dcad053ff1cd763bb3bfd9d8ec7023 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 271 9.9E-13 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS06740 c4dcad053ff1cd763bb3bfd9d8ec7023 280 PANTHER PTHR30193:SF20 2 280 4.3E-76 T 13-09-2016 THL1_RS06740 c4dcad053ff1cd763bb3bfd9d8ec7023 280 PANTHER PTHR30193 2 280 4.3E-76 T 13-09-2016 THL1_RS06740 c4dcad053ff1cd763bb3bfd9d8ec7023 280 Gene3D G3DSA:1.10.3720.10 14 275 1.7E-41 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS06740 c4dcad053ff1cd763bb3bfd9d8ec7023 280 SUPERFAMILY SSF161098 6 276 1.14E-45 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS03870 be6ca72e2a5efd4560ba56316c9e411b 322 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 314 29.478 T 13-09-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 THL1_RS03870 be6ca72e2a5efd4560ba56316c9e411b 322 SUPERFAMILY SSF56042 143 302 1.79E-35 T 13-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain THL1_RS03870 be6ca72e2a5efd4560ba56316c9e411b 322 Pfam PF00586 AIR synthase related protein, N-terminal domain 29 138 3.8E-23 T 13-09-2016 IPR016188 PurM-like, N-terminal domain THL1_RS03870 be6ca72e2a5efd4560ba56316c9e411b 322 Pfam PF02769 AIR synthase related protein, C-terminal domain 150 297 4.4E-8 T 13-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain THL1_RS03870 be6ca72e2a5efd4560ba56316c9e411b 322 SUPERFAMILY SSF55326 2 138 2.69E-33 T 13-09-2016 THL1_RS03870 be6ca72e2a5efd4560ba56316c9e411b 322 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 2 317 8.7E-92 T 13-09-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 THL1_RS03870 be6ca72e2a5efd4560ba56316c9e411b 322 Gene3D G3DSA:3.90.650.10 145 317 3.5E-42 T 13-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain THL1_RS03870 be6ca72e2a5efd4560ba56316c9e411b 322 PANTHER PTHR30270:SF0 2 321 1.7E-105 T 13-09-2016 THL1_RS03870 be6ca72e2a5efd4560ba56316c9e411b 322 PIRSF PIRSF005303 1 317 2.1E-76 T 13-09-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 THL1_RS03870 be6ca72e2a5efd4560ba56316c9e411b 322 Gene3D G3DSA:3.30.1330.10 2 141 2.5E-43 T 13-09-2016 IPR016188 PurM-like, N-terminal domain THL1_RS03870 be6ca72e2a5efd4560ba56316c9e411b 322 PANTHER PTHR30270 2 321 1.7E-105 T 13-09-2016 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897|UniPathway: UPA00060 THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 306 318 - T 13-09-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 SMART SM01086 657 747 6.7E-33 T 13-09-2016 IPR019489 Clp ATPase, C-terminal THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 62 1.1E-14 T 13-09-2016 IPR004176 Clp, N-terminal GO:0019538 THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 657 738 6.1E-25 T 13-09-2016 IPR019489 Clp ATPase, C-terminal THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 SUPERFAMILY SSF52540 441 736 3.26E-79 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 Gene3D G3DSA:3.40.50.300 174 354 1.2E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 PANTHER PTHR11638:SF111 1 754 0.0 T 13-09-2016 THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 SUPERFAMILY SSF81923 1 142 2.22E-60 T 13-09-2016 IPR004176 Clp, N-terminal GO:0019538 THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 SMART SM00382 210 355 6.0E-11 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 SMART SM00382 491 658 3.3E-10 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 Gene3D G3DSA:1.10.1780.10 1 142 1.6E-43 T 13-09-2016 IPR004176 Clp, N-terminal GO:0019538 THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 739 0.0 T 13-09-2016 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0004176 THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 Gene3D G3DSA:1.10.8.60 669 752 3.0E-31 T 13-09-2016 THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 PANTHER PTHR11638 1 754 0.0 T 13-09-2016 THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 Gene3D G3DSA:3.40.50.300 446 668 1.0E-58 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 537 555 1.0E-37 T 13-09-2016 IPR001270 ClpA/B family GO:0005524 THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 566 584 1.0E-37 T 13-09-2016 IPR001270 ClpA/B family GO:0005524 THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 599 613 1.0E-37 T 13-09-2016 IPR001270 ClpA/B family GO:0005524 THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 495 513 1.0E-37 T 13-09-2016 IPR001270 ClpA/B family GO:0005524 THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 522 540 - T 13-09-2016 IPR028299 ClpA/B, conserved site 2 THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 SUPERFAMILY SSF52540 172 425 1.22E-69 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 Pfam PF07724 AAA domain (Cdc48 subfamily) 490 651 3.9E-47 T 13-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 Gene3D G3DSA:1.10.8.60 355 438 2.0E-30 T 13-09-2016 THL1_RS12380 2fcadcd44ebdeb7ca1c21d8ab7292ea9 756 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 215 327 4.8E-12 T 13-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 THL1_RS11010 bc28ffe86755dc7a4c41e1bd6a1fa5ef 555 Pfam PF00501 AMP-binding enzyme 13 428 3.7E-92 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS11010 bc28ffe86755dc7a4c41e1bd6a1fa5ef 555 Gene3D G3DSA:3.40.50.980 177 351 9.7E-31 T 13-09-2016 THL1_RS11010 bc28ffe86755dc7a4c41e1bd6a1fa5ef 555 PANTHER PTHR24096 5 550 1.9E-248 T 13-09-2016 THL1_RS11010 bc28ffe86755dc7a4c41e1bd6a1fa5ef 555 Gene3D G3DSA:3.30.300.30 429 535 3.7E-7 T 13-09-2016 THL1_RS11010 bc28ffe86755dc7a4c41e1bd6a1fa5ef 555 SUPERFAMILY SSF56801 8 540 9.42E-117 T 13-09-2016 THL1_RS11010 bc28ffe86755dc7a4c41e1bd6a1fa5ef 555 Gene3D G3DSA:3.40.50.980 10 176 9.3E-34 T 13-09-2016 THL1_RS11010 bc28ffe86755dc7a4c41e1bd6a1fa5ef 555 PANTHER PTHR24096:SF249 5 550 1.9E-248 T 13-09-2016 THL1_RS11010 bc28ffe86755dc7a4c41e1bd6a1fa5ef 555 Gene3D G3DSA:2.30.38.10 363 422 1.8E-15 T 13-09-2016 THL1_RS11010 bc28ffe86755dc7a4c41e1bd6a1fa5ef 555 ProSitePatterns PS00455 Putative AMP-binding domain signature. 171 182 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS08240 3bbcc3c4a0bd23de587cb4bc3a131ed3 301 PANTHER PTHR12715:SF11 6 294 4.1E-70 T 13-09-2016 THL1_RS08240 3bbcc3c4a0bd23de587cb4bc3a131ed3 301 SUPERFAMILY SSF103481 190 291 7.45E-18 T 13-09-2016 THL1_RS08240 3bbcc3c4a0bd23de587cb4bc3a131ed3 301 PANTHER PTHR12715 6 294 4.1E-70 T 13-09-2016 THL1_RS08240 3bbcc3c4a0bd23de587cb4bc3a131ed3 301 SUPERFAMILY SSF103481 43 144 3.53E-16 T 13-09-2016 THL1_RS08240 3bbcc3c4a0bd23de587cb4bc3a131ed3 301 Pfam PF00892 EamA-like transporter family 10 140 3.3E-22 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS08240 3bbcc3c4a0bd23de587cb4bc3a131ed3 301 Pfam PF00892 EamA-like transporter family 154 286 2.3E-25 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS10145 2227f80884bb5b2e8597ee9a092d0aef 495 SUPERFAMILY SSF160246 11 74 3.92E-16 T 13-09-2016 THL1_RS10145 2227f80884bb5b2e8597ee9a092d0aef 495 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 315 329 - T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS10145 2227f80884bb5b2e8597ee9a092d0aef 495 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 11 492 5.3E-216 T 13-09-2016 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 THL1_RS10145 2227f80884bb5b2e8597ee9a092d0aef 495 PANTHER PTHR30258:SF9 8 495 0.0 T 13-09-2016 THL1_RS10145 2227f80884bb5b2e8597ee9a092d0aef 495 PANTHER PTHR30258 8 495 0.0 T 13-09-2016 THL1_RS10145 2227f80884bb5b2e8597ee9a092d0aef 495 Pfam PF00437 Type II/IV secretion system protein 122 387 3.5E-87 T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS10145 2227f80884bb5b2e8597ee9a092d0aef 495 Gene3D G3DSA:3.30.450.90 93 220 1.0E-53 T 13-09-2016 THL1_RS10145 2227f80884bb5b2e8597ee9a092d0aef 495 SUPERFAMILY SSF52540 104 492 1.03E-100 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10145 2227f80884bb5b2e8597ee9a092d0aef 495 Gene3D G3DSA:3.40.50.300 226 493 4.7E-95 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16915 3054ac4869a8dc1902423c7130da10ef 152 TIGRFAM TIGR02293 TAS_TIGR02293: putative toxin-antitoxin system antitoxin component, TIGR02293 family 36 151 4.3E-20 T 13-09-2016 IPR011979 Conserved hypothetical protein CHP02293 THL1_RS16915 3054ac4869a8dc1902423c7130da10ef 152 Pfam PF09722 Protein of unknown function (DUF2384) 100 149 1.4E-18 T 13-09-2016 IPR024467 Domain of unknown function DUF2384 THL1_RS03100 10dfb5e01eed2854fc6c48df07c81314 140 Pfam PF08780 Nucleotidyltransferase substrate binding protein like 10 133 3.8E-43 T 13-09-2016 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 THL1_RS03100 10dfb5e01eed2854fc6c48df07c81314 140 TIGRFAM TIGR01987 HI0074: nucleotidyltransferase substrate binding protein, HI0074 family 11 132 2.1E-29 T 13-09-2016 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 THL1_RS03100 10dfb5e01eed2854fc6c48df07c81314 140 Gene3D G3DSA:1.20.120.330 5 134 2.4E-50 T 13-09-2016 THL1_RS03100 10dfb5e01eed2854fc6c48df07c81314 140 SUPERFAMILY SSF81593 5 131 1.45E-43 T 13-09-2016 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 413 542 7.6E-36 T 13-09-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 SUPERFAMILY SSF55957 769 862 3.49E-26 T 13-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 PANTHER PTHR22573:SF28 391 862 4.9E-217 T 13-09-2016 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 559 655 5.4E-28 T 13-09-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 Gene3D G3DSA:3.40.120.10 653 769 3.9E-45 T 13-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 SUPERFAMILY SSF53738 660 764 2.59E-33 T 13-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 SUPERFAMILY SSF53738 412 551 1.49E-39 T 13-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 Gene3D G3DSA:3.30.310.50 772 860 2.7E-31 T 13-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 SUPERFAMILY SSF53738 556 657 1.49E-32 T 13-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 Gene3D G3DSA:3.40.120.10 411 549 2.8E-34 T 13-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 775 849 5.6E-13 T 13-09-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 502 511 - T 13-09-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 Gene3D G3DSA:3.40.120.10 574 651 1.7E-35 T 13-09-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 PANTHER PTHR22573 391 862 4.9E-217 T 13-09-2016 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 572 591 2.7E-24 T 13-09-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 501 515 2.7E-24 T 13-09-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 606 619 2.7E-24 T 13-09-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 635 650 2.7E-24 T 13-09-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS27835 379ed75d772511924e8671302a064cfb 863 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 660 768 2.8E-22 T 13-09-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THL1_RS11925 b943c593f5826dba26b4ac147d5dfe05 227 Gene3D G3DSA:1.10.10.10 127 221 3.0E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11925 b943c593f5826dba26b4ac147d5dfe05 227 SUPERFAMILY SSF52172 2 173 7.68E-42 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS11925 b943c593f5826dba26b4ac147d5dfe05 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 9.8E-18 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS11925 b943c593f5826dba26b4ac147d5dfe05 227 PANTHER PTHR26402 1 222 3.1E-109 T 13-09-2016 THL1_RS11925 b943c593f5826dba26b4ac147d5dfe05 227 SMART SM00448 1 113 6.6E-43 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS11925 b943c593f5826dba26b4ac147d5dfe05 227 Gene3D G3DSA:3.40.50.2300 2 126 9.7E-41 T 13-09-2016 THL1_RS11925 b943c593f5826dba26b4ac147d5dfe05 227 SMART SM00862 146 220 4.3E-18 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS11925 b943c593f5826dba26b4ac147d5dfe05 227 PANTHER PTHR26402:SF552 1 222 3.1E-109 T 13-09-2016 THL1_RS11925 b943c593f5826dba26b4ac147d5dfe05 227 Pfam PF00072 Response regulator receiver domain 3 114 2.3E-29 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS01530 0a5319535296b40a3c6bcc18cf7d3bbe 178 PANTHER PTHR22617 35 156 4.0E-23 T 13-09-2016 THL1_RS01530 0a5319535296b40a3c6bcc18cf7d3bbe 178 SMART SM00260 32 168 5.7E-27 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS01530 0a5319535296b40a3c6bcc18cf7d3bbe 178 SUPERFAMILY SSF50341 33 171 4.58E-28 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS01530 0a5319535296b40a3c6bcc18cf7d3bbe 178 Gene3D G3DSA:2.40.50.180 74 120 1.9E-6 T 13-09-2016 THL1_RS01530 0a5319535296b40a3c6bcc18cf7d3bbe 178 Pfam PF01584 CheW-like domain 38 170 2.1E-27 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 Gene3D G3DSA:3.30.70.270 379 540 1.2E-37 T 13-09-2016 THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 SUPERFAMILY SSF55781 37 190 1.74E-23 T 13-09-2016 IPR029016 GAF domain-like THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 SMART SM00052 546 791 3.8E-106 T 13-09-2016 IPR001633 EAL domain THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 374 530 6.5E-26 T 13-09-2016 IPR000160 GGDEF domain THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 Gene3D G3DSA:3.30.450.40 9 191 4.5E-30 T 13-09-2016 IPR029016 GAF domain-like THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 Gene3D G3DSA:3.30.450.40 192 370 5.3E-17 T 13-09-2016 IPR029016 GAF domain-like THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 Pfam PF00990 Diguanylate cyclase, GGDEF domain 377 530 9.0E-32 T 13-09-2016 IPR000160 GGDEF domain THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 Pfam PF13185 GAF domain 37 177 4.8E-19 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 Pfam PF13185 GAF domain 219 357 9.6E-10 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 SUPERFAMILY SSF55781 219 358 1.94E-15 T 13-09-2016 IPR029016 GAF domain-like THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 Gene3D G3DSA:3.20.20.450 550 796 3.6E-93 T 13-09-2016 IPR001633 EAL domain THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 PANTHER PTHR33121 287 301 2.9E-77 T 13-09-2016 THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 PANTHER PTHR33121 497 795 2.9E-77 T 13-09-2016 THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 SUPERFAMILY SSF141868 552 797 8.89E-86 T 13-09-2016 IPR001633 EAL domain THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 PANTHER PTHR33121:SF13 287 301 2.9E-77 T 13-09-2016 THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 PANTHER PTHR33121:SF13 497 795 2.9E-77 T 13-09-2016 THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 SMART SM00267 366 537 3.1E-34 T 13-09-2016 IPR000160 GGDEF domain THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 Pfam PF00563 EAL domain 552 786 8.1E-69 T 13-09-2016 IPR001633 EAL domain THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 SUPERFAMILY SSF55073 382 536 2.28E-33 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 SMART SM00065 37 187 1.1E-5 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS22350 1e31c3ca20cad02005f7781136a97d92 802 SMART SM00065 219 367 0.076 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS04845 a80bedc80fa75002f32d6eb193c89681 91 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.767 T 13-09-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS04845 a80bedc80fa75002f32d6eb193c89681 91 TIGRFAM TIGR00029 S20: ribosomal protein bS20 2 85 1.2E-30 T 13-09-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS04845 a80bedc80fa75002f32d6eb193c89681 91 PANTHER PTHR33398 2 90 2.4E-38 T 13-09-2016 THL1_RS04845 a80bedc80fa75002f32d6eb193c89681 91 Gene3D G3DSA:1.20.58.110 3 86 8.0E-33 T 13-09-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS04845 a80bedc80fa75002f32d6eb193c89681 91 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 19 91 8.0E-32 T 13-09-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS04845 a80bedc80fa75002f32d6eb193c89681 91 SUPERFAMILY SSF46992 3 86 3.53E-33 T 13-09-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS04845 a80bedc80fa75002f32d6eb193c89681 91 Pfam PF01649 Ribosomal protein S20 2 84 7.2E-29 T 13-09-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS07645 69b3d06b17a5fc8736547eabf17d8981 272 Gene3D G3DSA:3.40.192.10 25 110 7.2E-27 T 13-09-2016 THL1_RS07645 69b3d06b17a5fc8736547eabf17d8981 272 SUPERFAMILY SSF53223 9 105 1.15E-26 T 13-09-2016 THL1_RS07645 69b3d06b17a5fc8736547eabf17d8981 272 PANTHER PTHR21089 1 271 3.7E-150 T 13-09-2016 THL1_RS07645 69b3d06b17a5fc8736547eabf17d8981 272 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 26 93 1.4E-16 T 13-09-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS07645 69b3d06b17a5fc8736547eabf17d8981 272 PANTHER PTHR21089:SF9 1 271 3.7E-150 T 13-09-2016 THL1_RS07645 69b3d06b17a5fc8736547eabf17d8981 272 Gene3D G3DSA:3.40.50.720 111 267 4.0E-40 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07645 69b3d06b17a5fc8736547eabf17d8981 272 SUPERFAMILY SSF51735 106 266 2.27E-32 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS03425 4e54963adc81ea0019222a0a6dd598a0 249 Gene3D G3DSA:3.30.420.40 88 245 1.4E-40 T 13-09-2016 THL1_RS03425 4e54963adc81ea0019222a0a6dd598a0 249 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 249 18.123 T 13-09-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 THL1_RS03425 4e54963adc81ea0019222a0a6dd598a0 249 Pfam PF03309 Type III pantothenate kinase 2 199 1.5E-41 T 13-09-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 THL1_RS03425 4e54963adc81ea0019222a0a6dd598a0 249 SUPERFAMILY SSF53067 116 246 7.77E-31 T 13-09-2016 THL1_RS03425 4e54963adc81ea0019222a0a6dd598a0 249 SUPERFAMILY SSF53067 1 113 5.5E-24 T 13-09-2016 THL1_RS03425 4e54963adc81ea0019222a0a6dd598a0 249 PANTHER PTHR34265 1 245 2.1E-44 T 13-09-2016 THL1_RS03425 4e54963adc81ea0019222a0a6dd598a0 249 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 3 245 5.4E-27 T 13-09-2016 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 4.0E-66 T 13-09-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 4.0E-66 T 13-09-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 4.0E-66 T 13-09-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 4.0E-66 T 13-09-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 4.0E-66 T 13-09-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 4.0E-66 T 13-09-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 4.0E-66 T 13-09-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 SMART SM00851 955 1041 2.8E-34 T 13-09-2016 IPR011607 Methylglyoxal synthase-like domain THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 Gene3D G3DSA:3.40.50.1380 938 1071 8.1E-44 T 13-09-2016 IPR011607 Methylglyoxal synthase-like domain THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1062 13.119 T 13-09-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 Gene3D G3DSA:3.40.50.20 539 662 4.7E-61 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 PANTHER PTHR11405:SF5 1 1072 0.0 T 13-09-2016 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 SUPERFAMILY SSF56059 673 933 2.3E-102 T 13-09-2016 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 SUPERFAMILY SSF52440 1 127 1.09E-48 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 SUPERFAMILY SSF52335 938 1069 9.55E-42 T 13-09-2016 IPR011607 Methylglyoxal synthase-like domain THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 Gene3D G3DSA:3.30.1490.20 687 744 2.1E-25 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 SUPERFAMILY SSF52440 557 675 2.3E-49 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 1.3E-71 T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 673 875 3.1E-32 T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 SMART SM01096 424 547 9.2E-76 T 13-09-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 838 845 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 Gene3D G3DSA:1.10.1030.10 400 538 7.2E-51 T 13-09-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 427 547 7.4E-40 T 13-09-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 SUPERFAMILY SSF56059 128 401 1.41E-108 T 13-09-2016 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1067 13.395 T 13-09-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 Gene3D G3DSA:3.30.470.20 745 934 1.7E-77 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 Gene3D G3DSA:3.30.470.20 200 399 4.2E-75 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 709 723 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 PANTHER PTHR11405 1 1072 0.0 T 13-09-2016 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 Pfam PF02142 MGS-like domain 957 1041 1.0E-20 T 13-09-2016 IPR011607 Methylglyoxal synthase-like domain THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 Gene3D G3DSA:3.40.50.20 3 108 7.1E-44 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 Gene3D G3DSA:3.30.1490.20 142 199 1.6E-25 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 SUPERFAMILY SSF48108 396 554 1.2E-52 T 13-09-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1053 0.0 T 13-09-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 THL1_RS24465 4454ad42a11363822df74d4fa5bec405 1073 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS13575 fc73e3ff0e6affc97c79e9f1e9af375a 344 Gene3D G3DSA:3.40.190.10 143 269 1.9E-15 T 13-09-2016 THL1_RS13575 fc73e3ff0e6affc97c79e9f1e9af375a 344 PIRSF PIRSF019574 2 344 8.3E-86 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS13575 fc73e3ff0e6affc97c79e9f1e9af375a 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 119 135 3.6E-30 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS13575 fc73e3ff0e6affc97c79e9f1e9af375a 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 45 66 3.6E-30 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS13575 fc73e3ff0e6affc97c79e9f1e9af375a 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 247 266 3.6E-30 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS13575 fc73e3ff0e6affc97c79e9f1e9af375a 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 29 45 3.6E-30 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS13575 fc73e3ff0e6affc97c79e9f1e9af375a 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 72 86 3.6E-30 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS13575 fc73e3ff0e6affc97c79e9f1e9af375a 344 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 88 101 3.6E-30 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS13575 fc73e3ff0e6affc97c79e9f1e9af375a 344 PANTHER PTHR30222 1 344 2.4E-202 T 13-09-2016 THL1_RS13575 fc73e3ff0e6affc97c79e9f1e9af375a 344 PANTHER PTHR30222:SF9 1 344 2.4E-202 T 13-09-2016 THL1_RS13575 fc73e3ff0e6affc97c79e9f1e9af375a 344 Gene3D G3DSA:3.40.190.10 270 312 3.1E-47 T 13-09-2016 THL1_RS13575 fc73e3ff0e6affc97c79e9f1e9af375a 344 Gene3D G3DSA:3.40.190.10 23 128 3.1E-47 T 13-09-2016 THL1_RS13575 fc73e3ff0e6affc97c79e9f1e9af375a 344 SUPERFAMILY SSF53850 23 341 3.73E-77 T 13-09-2016 THL1_RS13575 fc73e3ff0e6affc97c79e9f1e9af375a 344 Pfam PF13416 Bacterial extracellular solute-binding protein 39 286 5.1E-30 T 13-09-2016 THL1_RS01935 ad660e28f4403c3ce3710144243d130b 447 SUPERFAMILY SSF103473 26 440 1.44E-73 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS01935 ad660e28f4403c3ce3710144243d130b 447 ProSitePatterns PS00216 Sugar transport proteins signature 1. 312 329 - T 13-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 THL1_RS01935 ad660e28f4403c3ce3710144243d130b 447 PANTHER PTHR23508 21 445 4.5E-142 T 13-09-2016 THL1_RS01935 ad660e28f4403c3ce3710144243d130b 447 Pfam PF07690 Major Facilitator Superfamily 53 310 6.7E-30 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS01935 ad660e28f4403c3ce3710144243d130b 447 PANTHER PTHR23508:SF17 21 445 4.5E-142 T 13-09-2016 THL1_RS01935 ad660e28f4403c3ce3710144243d130b 447 Gene3D G3DSA:1.20.1250.20 27 240 8.4E-32 T 13-09-2016 THL1_RS01935 ad660e28f4403c3ce3710144243d130b 447 Gene3D G3DSA:1.20.1250.20 256 442 1.7E-26 T 13-09-2016 THL1_RS23020 15e81a8c980569f83e5ca8b1b847490c 571 Pfam PF01368 DHH family 70 195 3.0E-8 T 13-09-2016 IPR001667 DDH domain THL1_RS23020 15e81a8c980569f83e5ca8b1b847490c 571 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 20 566 1.0E-150 T 13-09-2016 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 THL1_RS23020 15e81a8c980569f83e5ca8b1b847490c 571 PANTHER PTHR30255:SF2 18 571 2.0E-220 T 13-09-2016 THL1_RS23020 15e81a8c980569f83e5ca8b1b847490c 571 SUPERFAMILY SSF64182 44 459 5.76E-117 T 13-09-2016 THL1_RS23020 15e81a8c980569f83e5ca8b1b847490c 571 PANTHER PTHR30255 18 571 2.0E-220 T 13-09-2016 THL1_RS23020 15e81a8c980569f83e5ca8b1b847490c 571 Pfam PF02272 DHHA1 domain 376 443 1.4E-14 T 13-09-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 THL1_RS05650 5bb54e6853f090463846da3b47f39d18 315 SUPERFAMILY SSF56059 109 308 1.27E-55 T 13-09-2016 THL1_RS05650 5bb54e6853f090463846da3b47f39d18 315 Gene3D G3DSA:3.30.1490.20 118 186 1.4E-23 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS05650 5bb54e6853f090463846da3b47f39d18 315 Pfam PF07478 D-ala D-ala ligase C-terminus 116 307 4.0E-54 T 13-09-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS05650 5bb54e6853f090463846da3b47f39d18 315 SUPERFAMILY SSF52440 16 108 5.18E-31 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS05650 5bb54e6853f090463846da3b47f39d18 315 Pfam PF01820 D-ala D-ala ligase N-terminus 16 98 7.3E-22 T 13-09-2016 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS05650 5bb54e6853f090463846da3b47f39d18 315 Gene3D G3DSA:3.40.50.20 16 96 2.5E-29 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS05650 5bb54e6853f090463846da3b47f39d18 315 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 75 86 - T 13-09-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS05650 5bb54e6853f090463846da3b47f39d18 315 Gene3D G3DSA:3.30.470.20 97 115 9.9E-47 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS05650 5bb54e6853f090463846da3b47f39d18 315 Gene3D G3DSA:3.30.470.20 187 308 9.9E-47 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS05650 5bb54e6853f090463846da3b47f39d18 315 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 253 281 - T 13-09-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS05650 5bb54e6853f090463846da3b47f39d18 315 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 16 309 3.4E-105 T 13-09-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS05650 5bb54e6853f090463846da3b47f39d18 315 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 15 311 34.193 T 13-09-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS05650 5bb54e6853f090463846da3b47f39d18 315 PANTHER PTHR23132 16 313 3.8E-91 T 13-09-2016 THL1_RS01970 706acac15c183d01b9dea6e7695b42f6 317 SUPERFAMILY SSF46689 263 312 1.97E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01970 706acac15c183d01b9dea6e7695b42f6 317 Gene3D G3DSA:1.10.10.60 264 312 4.0E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01970 706acac15c183d01b9dea6e7695b42f6 317 Pfam PF01965 DJ-1/PfpI family 33 170 2.4E-18 T 13-09-2016 IPR002818 DJ-1/PfpI THL1_RS01970 706acac15c183d01b9dea6e7695b42f6 317 PANTHER PTHR11019:SF90 51 317 4.9E-70 T 13-09-2016 THL1_RS01970 706acac15c183d01b9dea6e7695b42f6 317 PANTHER PTHR11019:SF90 4 25 4.9E-70 T 13-09-2016 THL1_RS01970 706acac15c183d01b9dea6e7695b42f6 317 SUPERFAMILY SSF46689 211 261 8.96E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01970 706acac15c183d01b9dea6e7695b42f6 317 Gene3D G3DSA:1.10.10.60 217 263 1.8E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01970 706acac15c183d01b9dea6e7695b42f6 317 SUPERFAMILY SSF52317 2 192 8.06E-42 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS01970 706acac15c183d01b9dea6e7695b42f6 317 PANTHER PTHR11019 51 317 4.9E-70 T 13-09-2016 THL1_RS01970 706acac15c183d01b9dea6e7695b42f6 317 PANTHER PTHR11019 4 25 4.9E-70 T 13-09-2016 THL1_RS01970 706acac15c183d01b9dea6e7695b42f6 317 Pfam PF12833 Helix-turn-helix domain 233 311 7.0E-23 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS01970 706acac15c183d01b9dea6e7695b42f6 317 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 264 306 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS01970 706acac15c183d01b9dea6e7695b42f6 317 SMART SM00342 227 310 4.0E-23 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS01970 706acac15c183d01b9dea6e7695b42f6 317 Gene3D G3DSA:3.40.50.880 3 216 5.9E-41 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS19170 deb9a101e6c8417c362b62dca2c55b39 521 PANTHER PTHR30047 9 502 3.5E-213 T 13-09-2016 THL1_RS19170 deb9a101e6c8417c362b62dca2c55b39 521 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 51 498 6.2E-163 T 13-09-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 THL1_RS19170 deb9a101e6c8417c362b62dca2c55b39 521 ProSitePatterns PS01303 BCCT family of transporters signature. 316 325 - T 13-09-2016 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 THL1_RS19170 deb9a101e6c8417c362b62dca2c55b39 521 PANTHER PTHR30047:SF2 9 502 3.5E-213 T 13-09-2016 THL1_RS19170 deb9a101e6c8417c362b62dca2c55b39 521 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 13 497 5.5E-186 T 13-09-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 THL1_RS04185 e2d828f808d4fceef7d4240741c4c708 196 PANTHER PTHR23327:SF0 1 155 1.1E-51 T 13-09-2016 THL1_RS04185 e2d828f808d4fceef7d4240741c4c708 196 SMART SM00464 2 189 8.3E-7 T 13-09-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 THL1_RS04185 e2d828f808d4fceef7d4240741c4c708 196 SUPERFAMILY SSF88697 1 188 9.44E-44 T 13-09-2016 IPR015947 PUA-like domain THL1_RS04185 e2d828f808d4fceef7d4240741c4c708 196 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 2 188 1.4E-18 T 13-09-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 THL1_RS04185 e2d828f808d4fceef7d4240741c4c708 196 PANTHER PTHR23327 1 155 1.1E-51 T 13-09-2016 THL1_RS05865 d1571efc1867c8c8b61119f80242471c 165 PANTHER PTHR36115:SF2 8 165 8.4E-68 T 13-09-2016 THL1_RS05865 d1571efc1867c8c8b61119f80242471c 165 Pfam PF06271 RDD family 14 151 2.4E-28 T 13-09-2016 IPR010432 RDD THL1_RS05865 d1571efc1867c8c8b61119f80242471c 165 PANTHER PTHR36115 8 165 8.4E-68 T 13-09-2016 THL1_RS21245 2ceafc47531cba4745a2218016b066f1 250 Gene3D G3DSA:1.10.10.60 203 247 7.0E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21245 2ceafc47531cba4745a2218016b066f1 250 SMART SM00342 164 247 3.5E-29 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS21245 2ceafc47531cba4745a2218016b066f1 250 Pfam PF12833 Helix-turn-helix domain 170 247 2.4E-22 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS21245 2ceafc47531cba4745a2218016b066f1 250 SUPERFAMILY SSF46689 150 198 2.02E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21245 2ceafc47531cba4745a2218016b066f1 250 PANTHER PTHR11019 16 247 5.1E-86 T 13-09-2016 THL1_RS21245 2ceafc47531cba4745a2218016b066f1 250 Gene3D G3DSA:2.60.120.10 14 67 2.8E-5 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS21245 2ceafc47531cba4745a2218016b066f1 250 Gene3D G3DSA:1.10.10.60 150 202 6.9E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21245 2ceafc47531cba4745a2218016b066f1 250 PANTHER PTHR11019:SF39 16 247 5.1E-86 T 13-09-2016 THL1_RS21245 2ceafc47531cba4745a2218016b066f1 250 SUPERFAMILY SSF46689 201 247 2.78E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21245 2ceafc47531cba4745a2218016b066f1 250 SUPERFAMILY SSF51182 16 100 6.52E-5 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS23055 615b9a2098f3a68c5b9872abe15a5385 298 Gene3D G3DSA:1.10.443.10 113 289 9.8E-60 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS23055 615b9a2098f3a68c5b9872abe15a5385 298 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 5 298 64.062 T 13-09-2016 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 THL1_RS23055 615b9a2098f3a68c5b9872abe15a5385 298 Pfam PF00589 Phage integrase family 113 283 1.3E-51 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS23055 615b9a2098f3a68c5b9872abe15a5385 298 Gene3D G3DSA:1.10.150.130 8 100 1.2E-28 T 13-09-2016 IPR023109 Integrase/recombinase, N-terminal THL1_RS23055 615b9a2098f3a68c5b9872abe15a5385 298 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 5 298 31.954 T 13-09-2016 IPR023009 Tyrosine recombinase XerC/XerD THL1_RS23055 615b9a2098f3a68c5b9872abe15a5385 298 SUPERFAMILY SSF56349 8 289 4.12E-59 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS23055 615b9a2098f3a68c5b9872abe15a5385 298 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 11 297 2.7E-118 T 13-09-2016 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 THL1_RS23055 615b9a2098f3a68c5b9872abe15a5385 298 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 9 91 7.5E-23 T 13-09-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THL1_RS23055 615b9a2098f3a68c5b9872abe15a5385 298 PANTHER PTHR30349 8 297 3.0E-122 T 13-09-2016 THL1_RS23055 615b9a2098f3a68c5b9872abe15a5385 298 PANTHER PTHR30349:SF5 8 297 3.0E-122 T 13-09-2016 THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 PANTHER PTHR24423:SF354 91 107 3.8E-114 T 13-09-2016 THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 PANTHER PTHR24423:SF354 177 455 3.8E-114 T 13-09-2016 THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 SMART SM00388 237 303 5.5E-15 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 Pfam PF00672 HAMP domain 165 232 4.1E-14 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 303 1.3E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 4 455 5.0E-146 T 13-09-2016 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 PANTHER PTHR24423 91 107 3.8E-114 T 13-09-2016 THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 PANTHER PTHR24423 177 455 3.8E-114 T 13-09-2016 THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 SUPERFAMILY SSF55874 292 456 6.02E-35 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 SMART SM00304 183 236 6.3E-9 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 Gene3D G3DSA:1.10.287.130 227 299 2.7E-9 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 Gene3D G3DSA:3.30.565.10 308 461 1.7E-34 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 SUPERFAMILY SSF158472 184 233 4.58E-5 T 13-09-2016 THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 455 5.4E-17 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 SUPERFAMILY SSF47384 220 303 4.12E-16 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 SMART SM00387 346 458 1.1E-28 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 397 1.2E-7 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 437 1.2E-7 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS12855 c323956db8bc872caa9bc446517fcb7b 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 411 1.2E-7 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS06950 a8c475d8da69deec2a48a09eb1792092 206 Pfam PF02525 Flavodoxin-like fold 17 200 1.3E-38 T 13-09-2016 IPR003680 Flavodoxin-like fold THL1_RS06950 a8c475d8da69deec2a48a09eb1792092 206 Gene3D G3DSA:3.40.50.360 17 205 3.3E-48 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS06950 a8c475d8da69deec2a48a09eb1792092 206 SUPERFAMILY SSF52218 17 205 8.56E-53 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS06950 a8c475d8da69deec2a48a09eb1792092 206 PANTHER PTHR10204 16 205 1.3E-77 T 13-09-2016 THL1_RS06950 a8c475d8da69deec2a48a09eb1792092 206 PANTHER PTHR10204:SF40 16 205 1.3E-77 T 13-09-2016 THL1_RS04695 e6cce6f618161c7b614d68c5e8d3d717 158 Pfam PF06073 Bacterial protein of unknown function (DUF934) 49 155 1.3E-38 T 13-09-2016 IPR008318 Uncharacterised conserved protein UCP030820 THL1_RS04695 e6cce6f618161c7b614d68c5e8d3d717 158 PIRSF PIRSF030820 1 158 2.8E-55 T 13-09-2016 IPR008318 Uncharacterised conserved protein UCP030820 THL1_RS23080 b7729e00f6512a29e181f0ca98b4e0c0 178 Gene3D G3DSA:2.30.30.240 104 178 1.6E-30 T 13-09-2016 THL1_RS23080 b7729e00f6512a29e181f0ca98b4e0c0 178 PANTHER PTHR33692 9 178 3.5E-55 T 13-09-2016 THL1_RS23080 b7729e00f6512a29e181f0ca98b4e0c0 178 SUPERFAMILY SSF50346 104 177 6.47E-21 T 13-09-2016 IPR011033 PRC-barrel-like THL1_RS23080 b7729e00f6512a29e181f0ca98b4e0c0 178 SUPERFAMILY SSF50447 10 98 6.0E-25 T 13-09-2016 IPR009000 Translation protein, beta-barrel domain THL1_RS23080 b7729e00f6512a29e181f0ca98b4e0c0 178 Pfam PF01782 RimM N-terminal domain 14 94 5.8E-26 T 13-09-2016 IPR002676 RimM protein GO:0006364 THL1_RS23080 b7729e00f6512a29e181f0ca98b4e0c0 178 Gene3D G3DSA:2.40.30.60 5 98 5.3E-31 T 13-09-2016 IPR002676 RimM protein GO:0006364 THL1_RS23080 b7729e00f6512a29e181f0ca98b4e0c0 178 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 12 176 1.5E-53 T 13-09-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 THL1_RS23080 b7729e00f6512a29e181f0ca98b4e0c0 178 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 11 178 24.209 T 13-09-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 THL1_RS23080 b7729e00f6512a29e181f0ca98b4e0c0 178 Pfam PF05239 PRC-barrel domain 102 172 1.1E-7 T 13-09-2016 IPR027275 PRC-barrel domain THL1_RS11170 59fb51c10fde0dadd50252b67da9652b 363 SUPERFAMILY SSF53474 68 165 2.19E-22 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS11170 59fb51c10fde0dadd50252b67da9652b 363 SUPERFAMILY SSF53474 192 359 2.19E-22 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS11170 59fb51c10fde0dadd50252b67da9652b 363 Pfam PF12697 Alpha/beta hydrolase family 90 307 1.6E-7 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS11170 59fb51c10fde0dadd50252b67da9652b 363 PANTHER PTHR11177:SF162 110 353 3.3E-59 T 13-09-2016 THL1_RS11170 59fb51c10fde0dadd50252b67da9652b 363 Gene3D G3DSA:3.40.50.1820 33 362 1.6E-99 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS11170 59fb51c10fde0dadd50252b67da9652b 363 PANTHER PTHR11177 110 353 3.3E-59 T 13-09-2016 THL1_RS09540 0eb34ed685e26f8280672de78fe455b5 272 PANTHER PTHR38685 1 272 2.6E-69 T 13-09-2016 THL1_RS09540 0eb34ed685e26f8280672de78fe455b5 272 PANTHER PTHR38685:SF1 1 272 2.6E-69 T 13-09-2016 THL1_RS09540 0eb34ed685e26f8280672de78fe455b5 272 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 133 262 4.0E-66 T 13-09-2016 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 THL1_RS09540 0eb34ed685e26f8280672de78fe455b5 272 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 132 259 5.4E-49 T 13-09-2016 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 THL1_RS09540 0eb34ed685e26f8280672de78fe455b5 272 SUPERFAMILY SSF64383 130 267 1.96E-47 T 13-09-2016 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 THL1_RS09540 0eb34ed685e26f8280672de78fe455b5 272 Gene3D G3DSA:3.30.1400.10 129 266 1.4E-58 T 13-09-2016 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 THL1_RS09540 0eb34ed685e26f8280672de78fe455b5 272 Hamap MF_00509 Cell division protein ZipA [zipA]. 3 262 24.658 T 13-09-2016 IPR011919 Cell division protein ZipA GO:0000917|GO:0007049|GO:0016021 THL1_RS09540 0eb34ed685e26f8280672de78fe455b5 272 TIGRFAM TIGR02205 septum_zipA: cell division protein ZipA 5 260 1.8E-78 T 13-09-2016 IPR011919 Cell division protein ZipA GO:0000917|GO:0007049|GO:0016021 THL1_RS09540 0eb34ed685e26f8280672de78fe455b5 272 SMART SM00771 130 260 5.8E-66 T 13-09-2016 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0000917|GO:0016021 THL1_RS05180 a5f02e1259c68e9b9017673e91eaed47 751 SUPERFAMILY SSF56935 30 751 1.54E-139 T 13-09-2016 THL1_RS05180 a5f02e1259c68e9b9017673e91eaed47 751 Pfam PF07715 TonB-dependent Receptor Plug Domain 67 165 1.6E-20 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS05180 a5f02e1259c68e9b9017673e91eaed47 751 PANTHER PTHR32552 6 751 6.8E-254 T 13-09-2016 THL1_RS05180 a5f02e1259c68e9b9017673e91eaed47 751 Gene3D G3DSA:2.170.130.10 30 176 1.4E-34 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS05180 a5f02e1259c68e9b9017673e91eaed47 751 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 68 751 4.5E-105 T 13-09-2016 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 THL1_RS05180 a5f02e1259c68e9b9017673e91eaed47 751 Gene3D G3DSA:2.40.170.20 180 751 3.1E-147 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS05180 a5f02e1259c68e9b9017673e91eaed47 751 Pfam PF00593 TonB dependent receptor 500 749 1.4E-37 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS05180 a5f02e1259c68e9b9017673e91eaed47 751 PANTHER PTHR32552:SF8 6 751 6.8E-254 T 13-09-2016 IPR030148 Catecholate siderophore receptor Fiu GO:0004872|GO:0005506|GO:0009279|GO:0015891|GO:0016021 THL1_RS08135 4a230a1f1611e6b262741cedcd453346 166 SUPERFAMILY SSF117070 16 158 3.4E-32 T 13-09-2016 THL1_RS08135 4a230a1f1611e6b262741cedcd453346 166 ProDom PD010978 LATE EMBRYOGENESIS ABUNDANT DESICCATION SIMILAR PROTECTANT PROTEINS RELATED EMBRYOGENESIS-ABUNDANT EMBRYOGENESIS-LIKE 34 166 4.0E-4 T 13-09-2016 THL1_RS08135 4a230a1f1611e6b262741cedcd453346 166 Pfam PF03168 Late embryogenesis abundant protein 61 155 2.6E-22 T 13-09-2016 IPR004864 Late embryogenesis abundant protein, LEA-14 THL1_RS08135 4a230a1f1611e6b262741cedcd453346 166 SMART SM00769 40 159 8.4E-33 T 13-09-2016 IPR013990 Water stress and hypersensitive response domain GO:0009269 THL1_RS08135 4a230a1f1611e6b262741cedcd453346 166 Gene3D G3DSA:2.60.40.10 42 157 4.8E-18 T 13-09-2016 IPR013783 Immunoglobulin-like fold THL1_RS06585 0293278fb671152e45b7a8bb31a52f8e 576 Gene3D G3DSA:2.30.38.10 364 411 3.0E-13 T 13-09-2016 THL1_RS06585 0293278fb671152e45b7a8bb31a52f8e 576 Pfam PF00501 AMP-binding enzyme 14 417 6.0E-67 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS06585 0293278fb671152e45b7a8bb31a52f8e 576 SUPERFAMILY SSF56801 6 514 2.09E-115 T 13-09-2016 THL1_RS06585 0293278fb671152e45b7a8bb31a52f8e 576 Gene3D G3DSA:3.40.50.980 8 184 1.1E-18 T 13-09-2016 THL1_RS06585 0293278fb671152e45b7a8bb31a52f8e 576 Gene3D G3DSA:3.30.300.30 412 514 2.7E-25 T 13-09-2016 THL1_RS06585 0293278fb671152e45b7a8bb31a52f8e 576 ProSitePatterns PS00455 Putative AMP-binding domain signature. 181 192 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS06585 0293278fb671152e45b7a8bb31a52f8e 576 Gene3D G3DSA:3.40.50.980 185 345 1.7E-33 T 13-09-2016 THL1_RS06585 0293278fb671152e45b7a8bb31a52f8e 576 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 502 5.0E-16 T 13-09-2016 IPR025110 AMP-binding enzyme C-terminal domain THL1_RS06585 0293278fb671152e45b7a8bb31a52f8e 576 PANTHER PTHR24096 5 555 1.9E-134 T 13-09-2016 THL1_RS06585 0293278fb671152e45b7a8bb31a52f8e 576 PANTHER PTHR24096:SF170 5 555 1.9E-134 T 13-09-2016 THL1_RS14125 832641160abe80304e71b029d7f46ed7 818 Gene3D G3DSA:3.30.830.10 17 232 7.5E-43 T 13-09-2016 IPR011237 Peptidase M16 domain GO:0046872 THL1_RS14125 832641160abe80304e71b029d7f46ed7 818 SUPERFAMILY SSF63411 17 219 1.1E-39 T 13-09-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THL1_RS14125 832641160abe80304e71b029d7f46ed7 818 PANTHER PTHR11851 1 297 1.8E-41 T 13-09-2016 THL1_RS14125 832641160abe80304e71b029d7f46ed7 818 Gene3D G3DSA:3.30.830.10 619 790 7.3E-26 T 13-09-2016 IPR011237 Peptidase M16 domain GO:0046872 THL1_RS14125 832641160abe80304e71b029d7f46ed7 818 Pfam PF05193 Peptidase M16 inactive domain 186 341 6.0E-6 T 13-09-2016 IPR007863 Peptidase M16, C-terminal THL1_RS14125 832641160abe80304e71b029d7f46ed7 818 Pfam PF00675 Insulinase (Peptidase family M16) 28 151 7.7E-27 T 13-09-2016 IPR011765 Peptidase M16, N-terminal THL1_RS14125 832641160abe80304e71b029d7f46ed7 818 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 44 67 - T 13-09-2016 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 THL1_RS14125 832641160abe80304e71b029d7f46ed7 818 SUPERFAMILY SSF63411 629 791 1.0E-21 T 13-09-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THL1_RS14125 832641160abe80304e71b029d7f46ed7 818 TIGRFAM TIGR02110 PQQ_syn_pqqF: coenzyme PQQ biosynthesis protein PqqF 17 720 6.0E-155 T 13-09-2016 IPR011844 Coenzyme PQQ biosynthesis protein PqqF GO:0004222|GO:0006508|GO:0008270|GO:0018189 UniPathway: UPA00539 THL1_RS12960 4dfba38b536a5a95dec3a56080306d01 334 Gene3D G3DSA:3.40.50.720 3 160 5.4E-60 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS12960 4dfba38b536a5a95dec3a56080306d01 334 PANTHER PTHR10836 1 330 1.6E-223 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS12960 4dfba38b536a5a95dec3a56080306d01 334 SUPERFAMILY SSF51735 1 179 7.81E-54 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS12960 4dfba38b536a5a95dec3a56080306d01 334 Gene3D G3DSA:3.30.360.10 161 315 2.6E-69 T 13-09-2016 THL1_RS12960 4dfba38b536a5a95dec3a56080306d01 334 PIRSF PIRSF000149 1 332 2.0E-122 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS12960 4dfba38b536a5a95dec3a56080306d01 334 PANTHER PTHR10836:SF37 1 330 1.6E-223 T 13-09-2016 THL1_RS12960 4dfba38b536a5a95dec3a56080306d01 334 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 324 3.4E-118 T 13-09-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS12960 4dfba38b536a5a95dec3a56080306d01 334 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 152 2.7E-49 T 13-09-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS12960 4dfba38b536a5a95dec3a56080306d01 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 5.1E-61 T 13-09-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS12960 4dfba38b536a5a95dec3a56080306d01 334 SUPERFAMILY SSF55347 152 314 2.23E-65 T 13-09-2016 THL1_RS12960 4dfba38b536a5a95dec3a56080306d01 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 108 121 1.3E-30 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS12960 4dfba38b536a5a95dec3a56080306d01 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 1.3E-30 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS12960 4dfba38b536a5a95dec3a56080306d01 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 1.3E-30 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS12960 4dfba38b536a5a95dec3a56080306d01 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 1.3E-30 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS12960 4dfba38b536a5a95dec3a56080306d01 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 1.3E-30 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS12960 4dfba38b536a5a95dec3a56080306d01 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 13-09-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS12960 4dfba38b536a5a95dec3a56080306d01 334 SMART SM00846 3 152 5.5E-74 T 13-09-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS07660 7e4973907c3b31fed49a01454a4ce3fc 373 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 195 226 - T 13-09-2016 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 THL1_RS07660 7e4973907c3b31fed49a01454a4ce3fc 373 Gene3D G3DSA:3.20.20.120 128 360 1.1E-64 T 13-09-2016 IPR029065 Enolase C-terminal domain-like THL1_RS07660 7e4973907c3b31fed49a01454a4ce3fc 373 SMART SM00922 148 245 4.5E-17 T 13-09-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal THL1_RS07660 7e4973907c3b31fed49a01454a4ce3fc 373 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 10 129 7.2E-38 T 13-09-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain THL1_RS07660 7e4973907c3b31fed49a01454a4ce3fc 373 SUPERFAMILY SSF54826 6 130 3.39E-33 T 13-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THL1_RS07660 7e4973907c3b31fed49a01454a4ce3fc 373 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 104 129 - T 13-09-2016 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 THL1_RS07660 7e4973907c3b31fed49a01454a4ce3fc 373 TIGRFAM TIGR02534 mucon_cyclo: muconate and chloromuconate cycloisomerases 6 373 1.3E-157 T 13-09-2016 IPR013370 Muconate/chloromuconate cycloisomerase GO:0018849|GO:0018850|GO:0030145 THL1_RS07660 7e4973907c3b31fed49a01454a4ce3fc 373 Gene3D G3DSA:3.30.390.10 4 127 1.4E-45 T 13-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THL1_RS07660 7e4973907c3b31fed49a01454a4ce3fc 373 PANTHER PTHR13794 3 372 2.6E-122 T 13-09-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 THL1_RS07660 7e4973907c3b31fed49a01454a4ce3fc 373 SUPERFAMILY SSF51604 117 371 2.62E-63 T 13-09-2016 IPR029065 Enolase C-terminal domain-like THL1_RS07660 7e4973907c3b31fed49a01454a4ce3fc 373 PANTHER PTHR13794:SF55 3 372 2.6E-122 T 13-09-2016 THL1_RS07660 7e4973907c3b31fed49a01454a4ce3fc 373 Pfam PF13378 Enolase C-terminal domain-like 152 365 4.9E-45 T 13-09-2016 IPR029065 Enolase C-terminal domain-like THL1_RS26375 72a3ce5e3b7bd20d6fa7c1eecc00f511 445 SMART SM01086 333 431 6.8E-15 T 13-09-2016 IPR019489 Clp ATPase, C-terminal THL1_RS26375 72a3ce5e3b7bd20d6fa7c1eecc00f511 445 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 3 445 4.7E-214 T 13-09-2016 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 THL1_RS26375 72a3ce5e3b7bd20d6fa7c1eecc00f511 445 SUPERFAMILY SSF52540 3 443 5.81E-88 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26375 72a3ce5e3b7bd20d6fa7c1eecc00f511 445 Gene3D G3DSA:1.10.8.10 211 241 3.4E-31 T 13-09-2016 THL1_RS26375 72a3ce5e3b7bd20d6fa7c1eecc00f511 445 Gene3D G3DSA:1.10.8.10 110 175 3.4E-31 T 13-09-2016 THL1_RS26375 72a3ce5e3b7bd20d6fa7c1eecc00f511 445 Gene3D G3DSA:3.40.50.300 243 329 8.0E-52 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26375 72a3ce5e3b7bd20d6fa7c1eecc00f511 445 Gene3D G3DSA:3.40.50.300 3 109 8.0E-52 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26375 72a3ce5e3b7bd20d6fa7c1eecc00f511 445 Gene3D G3DSA:1.10.8.60 333 445 1.7E-29 T 13-09-2016 THL1_RS26375 72a3ce5e3b7bd20d6fa7c1eecc00f511 445 PANTHER PTHR11262 3 104 1.8E-204 T 13-09-2016 THL1_RS26375 72a3ce5e3b7bd20d6fa7c1eecc00f511 445 PANTHER PTHR11262 216 445 1.8E-204 T 13-09-2016 THL1_RS26375 72a3ce5e3b7bd20d6fa7c1eecc00f511 445 Pfam PF07724 AAA domain (Cdc48 subfamily) 185 327 8.0E-40 T 13-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 THL1_RS26375 72a3ce5e3b7bd20d6fa7c1eecc00f511 445 PANTHER PTHR11262:SF3 3 104 1.8E-204 T 13-09-2016 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 THL1_RS26375 72a3ce5e3b7bd20d6fa7c1eecc00f511 445 PANTHER PTHR11262:SF3 216 445 1.8E-204 T 13-09-2016 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 THL1_RS26375 72a3ce5e3b7bd20d6fa7c1eecc00f511 445 SMART SM00382 48 330 1.5E-11 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS26375 72a3ce5e3b7bd20d6fa7c1eecc00f511 445 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 52 136 9.6E-8 T 13-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 THL1_RS26375 72a3ce5e3b7bd20d6fa7c1eecc00f511 445 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 445 42.116 T 13-09-2016 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 THL1_RS16185 6eaa8d54c1d779aa1675f702152f5511 389 PANTHER PTHR35861 1 388 4.1E-119 T 13-09-2016 THL1_RS16185 6eaa8d54c1d779aa1675f702152f5511 389 PANTHER PTHR35861:SF1 1 388 4.1E-119 T 13-09-2016 THL1_RS16185 6eaa8d54c1d779aa1675f702152f5511 389 Pfam PF04984 Phage tail sheath protein 1 90 8.5E-11 T 13-09-2016 IPR007067 Tail sheath protein THL1_RS16185 6eaa8d54c1d779aa1675f702152f5511 389 Pfam PF04984 Phage tail sheath protein 93 376 7.1E-48 T 13-09-2016 IPR007067 Tail sheath protein THL1_RS08830 4173d44c7dd5c7db71e07c213efcb40b 294 SUPERFAMILY SSF46785 7 117 5.1E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08830 4173d44c7dd5c7db71e07c213efcb40b 294 Pfam PF03466 LysR substrate binding domain 101 287 7.7E-29 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS08830 4173d44c7dd5c7db71e07c213efcb40b 294 Gene3D G3DSA:1.10.10.10 12 94 5.8E-27 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08830 4173d44c7dd5c7db71e07c213efcb40b 294 Gene3D G3DSA:3.40.190.10 101 179 3.7E-12 T 13-09-2016 THL1_RS08830 4173d44c7dd5c7db71e07c213efcb40b 294 PANTHER PTHR30579 7 294 2.4E-118 T 13-09-2016 THL1_RS08830 4173d44c7dd5c7db71e07c213efcb40b 294 Gene3D G3DSA:3.40.190.10 180 247 1.2E-10 T 13-09-2016 THL1_RS08830 4173d44c7dd5c7db71e07c213efcb40b 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 1.2E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08830 4173d44c7dd5c7db71e07c213efcb40b 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 1.2E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08830 4173d44c7dd5c7db71e07c213efcb40b 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 1.2E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08830 4173d44c7dd5c7db71e07c213efcb40b 294 SUPERFAMILY SSF53850 101 291 1.35E-27 T 13-09-2016 THL1_RS08830 4173d44c7dd5c7db71e07c213efcb40b 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 73 2.0E-19 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08830 4173d44c7dd5c7db71e07c213efcb40b 294 PANTHER PTHR30579:SF0 7 294 2.4E-118 T 13-09-2016 THL1_RS00660 f87a2ac25b10cdeb5b7da0d5ea81e414 54 PRINTS PR00163 Rubredoxin signature 3 19 6.0E-9 T 13-09-2016 IPR024935 Rubredoxin domain GO:0005506 THL1_RS00660 f87a2ac25b10cdeb5b7da0d5ea81e414 54 PRINTS PR00163 Rubredoxin signature 33 49 6.0E-9 T 13-09-2016 IPR024935 Rubredoxin domain GO:0005506 THL1_RS00660 f87a2ac25b10cdeb5b7da0d5ea81e414 54 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 13-09-2016 IPR018527 Rubredoxin, iron-binding site GO:0046872 THL1_RS00660 f87a2ac25b10cdeb5b7da0d5ea81e414 54 Pfam PF00301 Rubredoxin 4 49 8.7E-23 T 13-09-2016 IPR024935 Rubredoxin domain GO:0005506 THL1_RS00660 f87a2ac25b10cdeb5b7da0d5ea81e414 54 SUPERFAMILY SSF57802 1 53 2.69E-22 T 13-09-2016 THL1_RS00660 f87a2ac25b10cdeb5b7da0d5ea81e414 54 Gene3D G3DSA:2.20.28.10 1 53 6.1E-26 T 13-09-2016 IPR004039 Rubredoxin-type fold THL1_RS00660 f87a2ac25b10cdeb5b7da0d5ea81e414 54 PIRSF PIRSF000071 1 54 1.3E-23 T 13-09-2016 IPR024922 Rubredoxin GO:0005506|GO:0009055 THL1_RS22035 12c33804ff2f059dd79ec632f4f91fa5 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 9.0E-34 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS22035 12c33804ff2f059dd79ec632f4f91fa5 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 9.0E-34 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS22035 12c33804ff2f059dd79ec632f4f91fa5 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 9.0E-34 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS22035 12c33804ff2f059dd79ec632f4f91fa5 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 9.0E-34 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS22035 12c33804ff2f059dd79ec632f4f91fa5 292 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 287 68.463 T 13-09-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS22035 12c33804ff2f059dd79ec632f4f91fa5 292 PANTHER PTHR12128 1 291 8.9E-146 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS22035 12c33804ff2f059dd79ec632f4f91fa5 292 Pfam PF00701 Dihydrodipicolinate synthetase family 2 285 5.1E-106 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS22035 12c33804ff2f059dd79ec632f4f91fa5 292 SMART SM01130 1 289 1.9E-148 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS22035 12c33804ff2f059dd79ec632f4f91fa5 292 PIRSF PIRSF001365 1 292 7.0E-98 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS22035 12c33804ff2f059dd79ec632f4f91fa5 292 SUPERFAMILY SSF51569 2 288 3.66E-105 T 13-09-2016 THL1_RS22035 12c33804ff2f059dd79ec632f4f91fa5 292 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 5 286 1.3E-113 T 13-09-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS22035 12c33804ff2f059dd79ec632f4f91fa5 292 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 13-09-2016 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS22035 12c33804ff2f059dd79ec632f4f91fa5 292 Gene3D G3DSA:3.20.20.70 1 291 5.7E-123 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS22035 12c33804ff2f059dd79ec632f4f91fa5 292 PANTHER PTHR12128:SF34 1 291 8.9E-146 T 13-09-2016 THL1_RS22035 12c33804ff2f059dd79ec632f4f91fa5 292 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 13-09-2016 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS17375 eb3003f631d1bb647e03ff3466df6ecf 351 PANTHER PTHR30222 1 348 1.9E-103 T 13-09-2016 THL1_RS17375 eb3003f631d1bb647e03ff3466df6ecf 351 Gene3D G3DSA:3.40.190.10 131 273 6.3E-29 T 13-09-2016 THL1_RS17375 eb3003f631d1bb647e03ff3466df6ecf 351 PANTHER PTHR30222:SF2 1 348 1.9E-103 T 13-09-2016 THL1_RS17375 eb3003f631d1bb647e03ff3466df6ecf 351 SUPERFAMILY SSF53850 20 349 1.81E-63 T 13-09-2016 THL1_RS17375 eb3003f631d1bb647e03ff3466df6ecf 351 Gene3D G3DSA:3.40.190.10 7 123 7.8E-8 T 13-09-2016 THL1_RS17375 eb3003f631d1bb647e03ff3466df6ecf 351 Gene3D G3DSA:3.40.190.10 274 304 7.8E-8 T 13-09-2016 THL1_RS17375 eb3003f631d1bb647e03ff3466df6ecf 351 Pfam PF13416 Bacterial extracellular solute-binding protein 42 315 7.3E-38 T 13-09-2016 THL1_RS12475 2dffa7a22974df17ea80ac3a1d288b33 517 SUPERFAMILY SSF49503 374 514 1.39E-19 T 13-09-2016 IPR008972 Cupredoxin THL1_RS12475 2dffa7a22974df17ea80ac3a1d288b33 517 SUPERFAMILY SSF49503 210 334 1.03E-16 T 13-09-2016 IPR008972 Cupredoxin THL1_RS12475 2dffa7a22974df17ea80ac3a1d288b33 517 PANTHER PTHR11709:SF2 164 517 1.1E-53 T 13-09-2016 THL1_RS12475 2dffa7a22974df17ea80ac3a1d288b33 517 PANTHER PTHR11709 164 517 1.1E-53 T 13-09-2016 THL1_RS12475 2dffa7a22974df17ea80ac3a1d288b33 517 Gene3D G3DSA:2.60.40.420 206 327 4.2E-24 T 13-09-2016 IPR008972 Cupredoxin THL1_RS12475 2dffa7a22974df17ea80ac3a1d288b33 517 ProSitePatterns PS00080 Multicopper oxidases signature 2. 499 510 - T 13-09-2016 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 THL1_RS12475 2dffa7a22974df17ea80ac3a1d288b33 517 SUPERFAMILY SSF49503 67 190 8.75E-8 T 13-09-2016 IPR008972 Cupredoxin THL1_RS12475 2dffa7a22974df17ea80ac3a1d288b33 517 Pfam PF07731 Multicopper oxidase 405 514 9.3E-16 T 13-09-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 THL1_RS12475 2dffa7a22974df17ea80ac3a1d288b33 517 Gene3D G3DSA:2.60.40.420 401 516 1.5E-23 T 13-09-2016 IPR008972 Cupredoxin THL1_RS12475 2dffa7a22974df17ea80ac3a1d288b33 517 Gene3D G3DSA:2.60.40.420 39 188 7.8E-10 T 13-09-2016 IPR008972 Cupredoxin THL1_RS08245 b777411caf3738a4877f694fbdd3b803 332 PIRSF PIRSF000149 1 332 3.2E-122 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS08245 b777411caf3738a4877f694fbdd3b803 332 PANTHER PTHR10836 1 326 1.1E-167 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS08245 b777411caf3738a4877f694fbdd3b803 332 SUPERFAMILY SSF51735 2 173 2.76E-52 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS08245 b777411caf3738a4877f694fbdd3b803 332 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 152 2.3E-50 T 13-09-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS08245 b777411caf3738a4877f694fbdd3b803 332 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 3 324 1.0E-114 T 13-09-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS08245 b777411caf3738a4877f694fbdd3b803 332 SMART SM00846 2 152 3.6E-73 T 13-09-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS08245 b777411caf3738a4877f694fbdd3b803 332 Gene3D G3DSA:3.40.50.720 1 160 3.4E-60 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS08245 b777411caf3738a4877f694fbdd3b803 332 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 312 6.0E-55 T 13-09-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS08245 b777411caf3738a4877f694fbdd3b803 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 4.2E-32 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS08245 b777411caf3738a4877f694fbdd3b803 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 4.2E-32 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS08245 b777411caf3738a4877f694fbdd3b803 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 4.2E-32 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS08245 b777411caf3738a4877f694fbdd3b803 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 4.2E-32 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS08245 b777411caf3738a4877f694fbdd3b803 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 111 124 4.2E-32 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS08245 b777411caf3738a4877f694fbdd3b803 332 PANTHER PTHR10836:SF50 1 326 1.1E-167 T 13-09-2016 THL1_RS08245 b777411caf3738a4877f694fbdd3b803 332 SUPERFAMILY SSF55347 152 313 9.04E-62 T 13-09-2016 THL1_RS08245 b777411caf3738a4877f694fbdd3b803 332 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 13-09-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS08245 b777411caf3738a4877f694fbdd3b803 332 Gene3D G3DSA:3.30.360.10 161 314 8.8E-63 T 13-09-2016 THL1_RS04905 49180f28dd3ed48b7c2be3f43f3705c2 1008 SUPERFAMILY SSF53300 41 147 1.2E-6 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS04905 49180f28dd3ed48b7c2be3f43f3705c2 1008 SUPERFAMILY SSF53300 194 212 1.2E-6 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS04905 49180f28dd3ed48b7c2be3f43f3705c2 1008 SUPERFAMILY SSF53300 242 312 1.2E-6 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS04905 49180f28dd3ed48b7c2be3f43f3705c2 1008 Pfam PF05567 Neisseria PilC beta-propeller domain 533 780 3.6E-17 T 13-09-2016 IPR008707 PilC beta-propeller domain THL1_RS04905 49180f28dd3ed48b7c2be3f43f3705c2 1008 SUPERFAMILY SSF82171 696 775 1.65E-6 T 13-09-2016 THL1_RS04905 49180f28dd3ed48b7c2be3f43f3705c2 1008 SUPERFAMILY SSF82171 578 640 1.65E-6 T 13-09-2016 THL1_RS04905 49180f28dd3ed48b7c2be3f43f3705c2 1008 Gene3D G3DSA:2.130.10.10 705 789 5.7E-4 T 13-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THL1_RS03070 e35f9b421cd2d48cc19fbb5362fc2d4c 180 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 5 173 3.1E-71 T 13-09-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 THL1_RS03070 e35f9b421cd2d48cc19fbb5362fc2d4c 180 Gene3D G3DSA:2.60.120.10 2 176 2.1E-78 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS03070 e35f9b421cd2d48cc19fbb5362fc2d4c 180 PANTHER PTHR21047 3 175 2.2E-73 T 13-09-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 THL1_RS03070 e35f9b421cd2d48cc19fbb5362fc2d4c 180 SUPERFAMILY SSF51182 2 175 2.77E-74 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS03070 e35f9b421cd2d48cc19fbb5362fc2d4c 180 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 175 1.0E-76 T 13-09-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 THL1_RS03070 e35f9b421cd2d48cc19fbb5362fc2d4c 180 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 167 2.0E-66 T 13-09-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 THL1_RS13955 b738a18c1734eb77212128225828c1a0 319 SUPERFAMILY SSF111369 62 176 8.24E-23 T 13-09-2016 THL1_RS13955 b738a18c1734eb77212128225828c1a0 319 PANTHER PTHR30386:SF7 1 319 1.3E-70 T 13-09-2016 THL1_RS13955 b738a18c1734eb77212128225828c1a0 319 Pfam PF13533 Biotin-lipoyl like 63 110 6.8E-12 T 13-09-2016 THL1_RS13955 b738a18c1734eb77212128225828c1a0 319 PANTHER PTHR30386 1 319 1.3E-70 T 13-09-2016 THL1_RS13955 b738a18c1734eb77212128225828c1a0 319 Gene3D G3DSA:2.40.50.100 64 96 3.3E-12 T 13-09-2016 THL1_RS13955 b738a18c1734eb77212128225828c1a0 319 Gene3D G3DSA:2.40.50.100 157 176 3.3E-12 T 13-09-2016 THL1_RS25850 6c5a3195d969f57a6b3df79180a93d00 389 PRINTS PR00721 Stomatin signature 217 235 1.6E-6 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS25850 6c5a3195d969f57a6b3df79180a93d00 389 PRINTS PR00721 Stomatin signature 88 110 1.6E-6 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS25850 6c5a3195d969f57a6b3df79180a93d00 389 PRINTS PR00721 Stomatin signature 135 156 1.6E-6 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS25850 6c5a3195d969f57a6b3df79180a93d00 389 Pfam PF01145 SPFH domain / Band 7 family 85 257 1.6E-28 T 13-09-2016 IPR001107 Band 7 domain THL1_RS25850 6c5a3195d969f57a6b3df79180a93d00 389 SUPERFAMILY SSF117892 113 246 1.57E-22 T 13-09-2016 IPR001107 Band 7 domain THL1_RS25850 6c5a3195d969f57a6b3df79180a93d00 389 SMART SM00244 81 241 1.2E-30 T 13-09-2016 IPR001107 Band 7 domain THL1_RS25850 6c5a3195d969f57a6b3df79180a93d00 389 PANTHER PTHR10264:SF51 4 380 1.3E-153 T 13-09-2016 IPR010201 HflK GO:0016021 THL1_RS25850 6c5a3195d969f57a6b3df79180a93d00 389 Pfam PF12221 Bacterial membrane protein N terminal 1 48 5.7E-16 T 13-09-2016 IPR020980 Menbrane protein HflK, N-terminal THL1_RS25850 6c5a3195d969f57a6b3df79180a93d00 389 PANTHER PTHR10264 4 380 1.3E-153 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS25850 6c5a3195d969f57a6b3df79180a93d00 389 TIGRFAM TIGR01933 hflK: HflK protein 83 344 1.6E-113 T 13-09-2016 IPR010201 HflK GO:0016021 THL1_RS14630 b7d8754e701b17e433c297cf57c5b3ad 446 Pfam PF03972 MmgE/PrpD family 3 426 1.5E-73 T 13-09-2016 IPR005656 MmgE/PrpD GO:0016829 THL1_RS14630 b7d8754e701b17e433c297cf57c5b3ad 446 Gene3D G3DSA:3.30.1330.120 257 381 4.9E-18 T 13-09-2016 THL1_RS14630 b7d8754e701b17e433c297cf57c5b3ad 446 PANTHER PTHR16943 3 428 1.4E-45 T 13-09-2016 IPR005656 MmgE/PrpD GO:0016829 THL1_RS14630 b7d8754e701b17e433c297cf57c5b3ad 446 SUPERFAMILY SSF103378 3 435 1.57E-82 T 13-09-2016 IPR005656 MmgE/PrpD GO:0016829 THL1_RS14630 b7d8754e701b17e433c297cf57c5b3ad 446 PANTHER PTHR16943:SF8 3 428 1.4E-45 T 13-09-2016 THL1_RS10230 4244bab9e7a67fb6a8142d73d463c370 368 Pfam PF00581 Rhodanese-like domain 256 339 5.6E-10 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS10230 4244bab9e7a67fb6a8142d73d463c370 368 SUPERFAMILY SSF52821 246 339 1.17E-20 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS10230 4244bab9e7a67fb6a8142d73d463c370 368 SMART SM00450 253 346 1.9E-9 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS10230 4244bab9e7a67fb6a8142d73d463c370 368 SMART SM00100 15 128 2.8E-4 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS10230 4244bab9e7a67fb6a8142d73d463c370 368 SMART SM00100 143 260 2.2E-11 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS10230 4244bab9e7a67fb6a8142d73d463c370 368 SUPERFAMILY SSF51206 133 246 1.01E-23 T 13-09-2016 IPR018490 Cyclic nucleotide-binding-like THL1_RS10230 4244bab9e7a67fb6a8142d73d463c370 368 SUPERFAMILY SSF51206 7 123 4.19E-15 T 13-09-2016 IPR018490 Cyclic nucleotide-binding-like THL1_RS10230 4244bab9e7a67fb6a8142d73d463c370 368 Pfam PF00027 Cyclic nucleotide-binding domain 162 246 2.8E-18 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS10230 4244bab9e7a67fb6a8142d73d463c370 368 Pfam PF00027 Cyclic nucleotide-binding domain 36 111 2.3E-7 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS10230 4244bab9e7a67fb6a8142d73d463c370 368 PANTHER PTHR24353 152 241 7.2E-17 T 13-09-2016 THL1_RS10230 4244bab9e7a67fb6a8142d73d463c370 368 Gene3D G3DSA:2.60.120.10 9 116 1.5E-9 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS10230 4244bab9e7a67fb6a8142d73d463c370 368 Gene3D G3DSA:2.60.120.10 133 247 3.3E-25 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS10230 4244bab9e7a67fb6a8142d73d463c370 368 Gene3D G3DSA:3.40.250.10 248 339 3.4E-18 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS19550 966b1d9d974cd40b5540a24f71163d56 146 PANTHER PTHR38766:SF1 9 144 2.9E-26 T 13-09-2016 THL1_RS19550 966b1d9d974cd40b5540a24f71163d56 146 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 50 117 1.5E-20 T 13-09-2016 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 THL1_RS19550 966b1d9d974cd40b5540a24f71163d56 146 Pfam PF04347 Flagellar biosynthesis protein, FliO 62 141 1.1E-19 T 13-09-2016 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 THL1_RS19550 966b1d9d974cd40b5540a24f71163d56 146 PANTHER PTHR38766 9 144 2.9E-26 T 13-09-2016 THL1_RS13600 59ce9ddee65d6b78e6239f2f5278d99a 305 PANTHER PTHR18866:SF74 151 263 6.3E-35 T 13-09-2016 THL1_RS13600 59ce9ddee65d6b78e6239f2f5278d99a 305 Pfam PF02626 Allophanate hydrolase subunit 2 25 285 1.0E-72 T 13-09-2016 IPR003778 Carboxyltransferase domain, subdomain A and B THL1_RS13600 59ce9ddee65d6b78e6239f2f5278d99a 305 SUPERFAMILY SSF50891 194 287 1.1E-5 T 13-09-2016 IPR029000 Cyclophilin-like domain THL1_RS13600 59ce9ddee65d6b78e6239f2f5278d99a 305 SMART SM00797 24 303 1.7E-114 T 13-09-2016 IPR003778 Carboxyltransferase domain, subdomain A and B THL1_RS13600 59ce9ddee65d6b78e6239f2f5278d99a 305 PANTHER PTHR18866 151 263 6.3E-35 T 13-09-2016 THL1_RS18945 d92e128a06b0e82148c1e8d933ca74e6 516 Gene3D G3DSA:3.50.50.60 325 491 2.1E-18 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS18945 d92e128a06b0e82148c1e8d933ca74e6 516 Gene3D G3DSA:3.50.50.60 9 226 3.8E-56 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS18945 d92e128a06b0e82148c1e8d933ca74e6 516 PANTHER PTHR23023:SF132 12 488 2.4E-233 T 13-09-2016 THL1_RS18945 d92e128a06b0e82148c1e8d933ca74e6 516 Pfam PF00743 Flavin-binding monooxygenase-like 15 352 1.7E-15 T 13-09-2016 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 THL1_RS18945 d92e128a06b0e82148c1e8d933ca74e6 516 PANTHER PTHR23023 12 488 2.4E-233 T 13-09-2016 THL1_RS18945 d92e128a06b0e82148c1e8d933ca74e6 516 SUPERFAMILY SSF51905 286 480 3.4E-25 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS18945 d92e128a06b0e82148c1e8d933ca74e6 516 SUPERFAMILY SSF51905 12 233 2.59E-51 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS13510 bd2ed2d57706dc03c6165c481b8b84b9 271 SUPERFAMILY SSF52833 137 265 1.55E-30 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS13510 bd2ed2d57706dc03c6165c481b8b84b9 271 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 6 101 3.9E-6 T 13-09-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 THL1_RS13510 bd2ed2d57706dc03c6165c481b8b84b9 271 ProSitePatterns PS00194 Thioredoxin family active site. 160 178 - T 13-09-2016 IPR017937 Thioredoxin, conserved site GO:0045454 THL1_RS13510 bd2ed2d57706dc03c6165c481b8b84b9 271 Gene3D G3DSA:3.40.30.10 47 71 6.0E-35 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS13510 bd2ed2d57706dc03c6165c481b8b84b9 271 Gene3D G3DSA:3.40.30.10 129 265 6.0E-35 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS13510 bd2ed2d57706dc03c6165c481b8b84b9 271 Pfam PF08534 Redoxin 133 243 4.5E-12 T 13-09-2016 IPR013740 Redoxin GO:0016491 THL1_RS13510 bd2ed2d57706dc03c6165c481b8b84b9 271 PANTHER PTHR10438:SF244 219 265 7.9E-26 T 13-09-2016 THL1_RS13510 bd2ed2d57706dc03c6165c481b8b84b9 271 PANTHER PTHR10438:SF244 97 195 7.9E-26 T 13-09-2016 THL1_RS13510 bd2ed2d57706dc03c6165c481b8b84b9 271 PANTHER PTHR10438 219 265 7.9E-26 T 13-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THL1_RS13510 bd2ed2d57706dc03c6165c481b8b84b9 271 PANTHER PTHR10438 97 195 7.9E-26 T 13-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THL1_RS28135 91bdce1b35a615eeb1540b26b0eee526 474 ProSitePatterns PS00163 Fumarate lyases signature. 322 331 - T 13-09-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 THL1_RS28135 91bdce1b35a615eeb1540b26b0eee526 474 PANTHER PTHR11444:SF25 1 468 9.8E-270 T 13-09-2016 THL1_RS28135 91bdce1b35a615eeb1540b26b0eee526 474 Gene3D G3DSA:1.10.40.30 424 468 6.7E-21 T 13-09-2016 THL1_RS28135 91bdce1b35a615eeb1540b26b0eee526 474 Pfam PF10415 Fumarase C C-terminus 413 465 3.3E-20 T 13-09-2016 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 THL1_RS28135 91bdce1b35a615eeb1540b26b0eee526 474 PRINTS PR00145 Argininosuccinate lyase family signature 322 338 8.8E-5 T 13-09-2016 THL1_RS28135 91bdce1b35a615eeb1540b26b0eee526 474 PRINTS PR00145 Argininosuccinate lyase family signature 138 160 8.8E-5 T 13-09-2016 THL1_RS28135 91bdce1b35a615eeb1540b26b0eee526 474 PRINTS PR00145 Argininosuccinate lyase family signature 179 199 8.8E-5 T 13-09-2016 THL1_RS28135 91bdce1b35a615eeb1540b26b0eee526 474 Pfam PF00206 Lyase 15 347 2.0E-110 T 13-09-2016 IPR022761 Fumarate lyase, N-terminal THL1_RS28135 91bdce1b35a615eeb1540b26b0eee526 474 Gene3D G3DSA:1.20.200.10 144 423 7.1E-89 T 13-09-2016 THL1_RS28135 91bdce1b35a615eeb1540b26b0eee526 474 Gene3D G3DSA:1.10.275.10 6 143 2.4E-54 T 13-09-2016 IPR024083 Fumarase/histidase, N-terminal THL1_RS28135 91bdce1b35a615eeb1540b26b0eee526 474 PANTHER PTHR11444 1 468 9.8E-270 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS28135 91bdce1b35a615eeb1540b26b0eee526 474 SUPERFAMILY SSF48557 7 468 8.64E-143 T 13-09-2016 IPR008948 L-Aspartase-like GO:0003824 THL1_RS28135 91bdce1b35a615eeb1540b26b0eee526 474 PRINTS PR00149 Fumarate lyase superfamily signature 276 303 1.3E-28 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS28135 91bdce1b35a615eeb1540b26b0eee526 474 PRINTS PR00149 Fumarate lyase superfamily signature 139 157 1.3E-28 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS28135 91bdce1b35a615eeb1540b26b0eee526 474 PRINTS PR00149 Fumarate lyase superfamily signature 322 338 1.3E-28 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS28135 91bdce1b35a615eeb1540b26b0eee526 474 PRINTS PR00149 Fumarate lyase superfamily signature 184 202 1.3E-28 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS01940 6836b103d0443e7c2683d45324cc2446 375 PANTHER PTHR30222:SF5 1 374 4.8E-38 T 13-09-2016 THL1_RS01940 6836b103d0443e7c2683d45324cc2446 375 Pfam PF13416 Bacterial extracellular solute-binding protein 54 314 4.0E-29 T 13-09-2016 THL1_RS01940 6836b103d0443e7c2683d45324cc2446 375 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 136 152 3.0E-9 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS01940 6836b103d0443e7c2683d45324cc2446 375 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 44 60 3.0E-9 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS01940 6836b103d0443e7c2683d45324cc2446 375 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 162 176 3.0E-9 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS01940 6836b103d0443e7c2683d45324cc2446 375 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 60 81 3.0E-9 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS01940 6836b103d0443e7c2683d45324cc2446 375 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 88 102 3.0E-9 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS01940 6836b103d0443e7c2683d45324cc2446 375 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 264 283 3.0E-9 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS01940 6836b103d0443e7c2683d45324cc2446 375 PANTHER PTHR30222 1 374 4.8E-38 T 13-09-2016 THL1_RS01940 6836b103d0443e7c2683d45324cc2446 375 SUPERFAMILY SSF53850 38 372 1.94E-58 T 13-09-2016 THL1_RS01940 6836b103d0443e7c2683d45324cc2446 375 Gene3D G3DSA:3.40.190.10 287 315 3.3E-26 T 13-09-2016 THL1_RS01940 6836b103d0443e7c2683d45324cc2446 375 Gene3D G3DSA:3.40.190.10 37 145 3.3E-26 T 13-09-2016 THL1_RS01940 6836b103d0443e7c2683d45324cc2446 375 Gene3D G3DSA:3.40.190.10 147 286 1.3E-14 T 13-09-2016 THL1_RS09600 c89daed5d3836ab8b09d605307e3298a 405 SUPERFAMILY SSF52172 53 136 6.3E-6 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS09600 c89daed5d3836ab8b09d605307e3298a 405 Gene3D G3DSA:3.40.50.300 146 386 5.6E-47 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09600 c89daed5d3836ab8b09d605307e3298a 405 SUPERFAMILY SSF52540 147 386 1.6E-38 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09600 c89daed5d3836ab8b09d605307e3298a 405 Gene3D G3DSA:3.40.50.2300 81 138 8.2E-4 T 13-09-2016 THL1_RS09600 c89daed5d3836ab8b09d605307e3298a 405 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 149 340 3.6E-18 T 13-09-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THL1_RS09600 c89daed5d3836ab8b09d605307e3298a 405 PANTHER PTHR13696 85 396 2.6E-31 T 13-09-2016 THL1_RS01485 95205de1b420a4580293669651184eb2 423 SUPERFAMILY SSF51556 56 367 2.56E-85 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS01485 95205de1b420a4580293669651184eb2 423 Pfam PF01979 Amidohydrolase family 148 419 4.1E-16 T 13-09-2016 IPR006680 Amidohydrolase-related GO:0016787 THL1_RS01485 95205de1b420a4580293669651184eb2 423 PANTHER PTHR11647 1 422 1.3E-142 T 13-09-2016 THL1_RS01485 95205de1b420a4580293669651184eb2 423 PANTHER PTHR11647:SF70 1 422 1.3E-142 T 13-09-2016 THL1_RS01485 95205de1b420a4580293669651184eb2 423 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 423 31.851 T 13-09-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS01485 95205de1b420a4580293669651184eb2 423 Gene3D G3DSA:3.20.20.140 69 385 4.5E-85 T 13-09-2016 THL1_RS01485 95205de1b420a4580293669651184eb2 423 Gene3D G3DSA:2.30.40.10 3 68 1.4E-10 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS01485 95205de1b420a4580293669651184eb2 423 SUPERFAMILY SSF51338 367 422 4.74E-24 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS01485 95205de1b420a4580293669651184eb2 423 SUPERFAMILY SSF51338 1 55 4.74E-24 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS01485 95205de1b420a4580293669651184eb2 423 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 22 421 9.0E-89 T 13-09-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS26175 34dcaa33fd788e083e5b9ffc274270bf 347 PANTHER PTHR30160:SF7 1 347 2.2E-105 T 13-09-2016 THL1_RS26175 34dcaa33fd788e083e5b9ffc274270bf 347 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 69 318 4.6E-86 T 13-09-2016 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 THL1_RS26175 34dcaa33fd788e083e5b9ffc274270bf 347 TIGRFAM TIGR02195 heptsyl_trn_II: lipopolysaccharide heptosyltransferase II 2 337 8.7E-162 T 13-09-2016 IPR011910 Lipopolysaccharide heptosyltransferase II GO:0009103|GO:0016757 KEGG: 00231+2.-.-.-|UniPathway: UPA00958 THL1_RS26175 34dcaa33fd788e083e5b9ffc274270bf 347 SUPERFAMILY SSF53756 1 337 4.29E-98 T 13-09-2016 THL1_RS26175 34dcaa33fd788e083e5b9ffc274270bf 347 Gene3D G3DSA:3.40.50.2000 1 148 6.5E-51 T 13-09-2016 THL1_RS26175 34dcaa33fd788e083e5b9ffc274270bf 347 Gene3D G3DSA:3.40.50.2000 162 337 2.4E-56 T 13-09-2016 THL1_RS26175 34dcaa33fd788e083e5b9ffc274270bf 347 PANTHER PTHR30160 1 347 2.2E-105 T 13-09-2016 THL1_RS23040 37840896231936acf323b001767d2824 469 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 102 116 - T 13-09-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 THL1_RS23040 37840896231936acf323b001767d2824 469 Gene3D G3DSA:3.40.50.1100 131 202 7.9E-7 T 13-09-2016 THL1_RS23040 37840896231936acf323b001767d2824 469 PANTHER PTHR10314:SF1 361 468 3.0E-166 T 13-09-2016 THL1_RS23040 37840896231936acf323b001767d2824 469 PANTHER PTHR10314:SF1 25 36 3.0E-166 T 13-09-2016 THL1_RS23040 37840896231936acf323b001767d2824 469 PANTHER PTHR10314 361 468 3.0E-166 T 13-09-2016 THL1_RS23040 37840896231936acf323b001767d2824 469 PANTHER PTHR10314 25 36 3.0E-166 T 13-09-2016 THL1_RS23040 37840896231936acf323b001767d2824 469 SUPERFAMILY SSF53686 1 461 2.27E-164 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS23040 37840896231936acf323b001767d2824 469 Gene3D G3DSA:3.40.50.1100 203 437 4.1E-95 T 13-09-2016 THL1_RS23040 37840896231936acf323b001767d2824 469 Pfam PF14821 Threonine synthase N terminus 2 80 1.5E-29 T 13-09-2016 IPR029144 Threonine synthase, N-terminal THL1_RS23040 37840896231936acf323b001767d2824 469 PANTHER PTHR10314:SF1 53 329 3.0E-166 T 13-09-2016 THL1_RS23040 37840896231936acf323b001767d2824 469 PANTHER PTHR10314 53 329 3.0E-166 T 13-09-2016 THL1_RS23040 37840896231936acf323b001767d2824 469 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 92 398 1.4E-24 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS23040 37840896231936acf323b001767d2824 469 TIGRFAM TIGR00260 thrC: threonine synthase 67 423 5.9E-80 T 13-09-2016 IPR004450 Threonine synthase-like THL1_RS23040 37840896231936acf323b001767d2824 469 Gene3D G3DSA:3.90.1380.10 1 85 1.2E-30 T 13-09-2016 IPR029144 Threonine synthase, N-terminal THL1_RS18925 9df35c6baa7a776ebbe079bf587b7559 448 Gene3D G3DSA:3.40.50.2300 9 138 3.8E-33 T 13-09-2016 THL1_RS18925 9df35c6baa7a776ebbe079bf587b7559 448 PANTHER PTHR26402 8 362 1.2E-53 T 13-09-2016 THL1_RS18925 9df35c6baa7a776ebbe079bf587b7559 448 SMART SM00448 8 120 5.7E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS18925 9df35c6baa7a776ebbe079bf587b7559 448 Pfam PF00072 Response regulator receiver domain 11 117 1.3E-20 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS18925 9df35c6baa7a776ebbe079bf587b7559 448 PANTHER PTHR26402:SF515 8 362 1.2E-53 T 13-09-2016 THL1_RS18925 9df35c6baa7a776ebbe079bf587b7559 448 Pfam PF13487 HD domain 255 315 2.5E-17 T 13-09-2016 THL1_RS18925 9df35c6baa7a776ebbe079bf587b7559 448 SUPERFAMILY SSF52172 7 172 1.57E-34 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS18925 9df35c6baa7a776ebbe079bf587b7559 448 SUPERFAMILY SSF109604 208 362 4.93E-10 T 13-09-2016 THL1_RS12590 d04421ac351eae25953dbd70c5d28cd9 166 PANTHER PTHR33990:SF2 5 166 2.6E-76 T 13-09-2016 THL1_RS12590 d04421ac351eae25953dbd70c5d28cd9 166 Gene3D G3DSA:3.10.180.10 6 137 2.1E-48 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS12590 d04421ac351eae25953dbd70c5d28cd9 166 PIRSF PIRSF021700 3 166 5.6E-61 T 13-09-2016 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase THL1_RS12590 d04421ac351eae25953dbd70c5d28cd9 166 PANTHER PTHR33990 5 166 2.6E-76 T 13-09-2016 THL1_RS12590 d04421ac351eae25953dbd70c5d28cd9 166 SUPERFAMILY SSF54593 7 165 7.5E-51 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS12590 d04421ac351eae25953dbd70c5d28cd9 166 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 7 126 6.8E-48 T 13-09-2016 IPR028973 3-demethylubiquinone-9 3-methyltransferase THL1_RS17365 6da18f73b2eed684cd6062e493b13889 424 PANTHER PTHR30193 12 79 3.0E-121 T 13-09-2016 THL1_RS17365 6da18f73b2eed684cd6062e493b13889 424 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 224 415 9.0E-18 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS17365 6da18f73b2eed684cd6062e493b13889 424 PANTHER PTHR30193 184 423 3.0E-121 T 13-09-2016 THL1_RS17365 6da18f73b2eed684cd6062e493b13889 424 PANTHER PTHR30193:SF8 184 423 3.0E-121 T 13-09-2016 THL1_RS17365 6da18f73b2eed684cd6062e493b13889 424 Gene3D G3DSA:1.10.3720.10 32 89 2.2E-53 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS17365 6da18f73b2eed684cd6062e493b13889 424 Gene3D G3DSA:1.10.3720.10 195 414 2.2E-53 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS17365 6da18f73b2eed684cd6062e493b13889 424 PANTHER PTHR30193:SF8 12 79 3.0E-121 T 13-09-2016 THL1_RS17365 6da18f73b2eed684cd6062e493b13889 424 SUPERFAMILY SSF161098 199 412 2.09E-49 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS14765 2d0ff6e4d108811728670d896fe01d7b 253 PIRSF PIRSF039085 1 253 5.3E-111 T 13-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 THL1_RS14765 2d0ff6e4d108811728670d896fe01d7b 253 SMART SM00382 28 226 1.5E-15 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS14765 2d0ff6e4d108811728670d896fe01d7b 253 Pfam PF00005 ABC transporter 19 178 1.3E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS14765 2d0ff6e4d108811728670d896fe01d7b 253 PANTHER PTHR24220 5 253 7.7E-148 T 13-09-2016 THL1_RS14765 2d0ff6e4d108811728670d896fe01d7b 253 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS14765 2d0ff6e4d108811728670d896fe01d7b 253 Gene3D G3DSA:3.40.50.300 4 248 2.3E-79 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14765 2d0ff6e4d108811728670d896fe01d7b 253 PANTHER PTHR24220:SF347 5 253 7.7E-148 T 13-09-2016 THL1_RS14765 2d0ff6e4d108811728670d896fe01d7b 253 SUPERFAMILY SSF52540 4 247 9.38E-71 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 Pfam PF02938 GAD domain 309 408 7.7E-32 T 13-09-2016 IPR029351 GAD domain THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 PANTHER PTHR22594:SF5 372 571 4.5E-250 T 13-09-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 PANTHER PTHR22594:SF5 1 298 4.5E-250 T 13-09-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 582 3.0E-243 T 13-09-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 Pfam PF00152 tRNA synthetases class II (D, K and N) 120 558 1.1E-108 T 13-09-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 1 563 37.776 T 13-09-2016 THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 SUPERFAMILY SSF50249 1 105 1.9E-33 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 SUPERFAMILY SSF55261 291 421 1.79E-44 T 13-09-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 Gene3D G3DSA:3.30.930.10 133 277 1.4E-112 T 13-09-2016 THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 Gene3D G3DSA:3.30.930.10 416 585 1.4E-112 T 13-09-2016 THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 PANTHER PTHR22594 1 298 4.5E-250 T 13-09-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 SUPERFAMILY SSF55681 110 289 1.39E-102 T 13-09-2016 THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 SUPERFAMILY SSF55681 421 584 1.39E-102 T 13-09-2016 THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 192 204 4.7E-27 T 13-09-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 209 222 4.7E-27 T 13-09-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 518 532 4.7E-27 T 13-09-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 PRINTS PR01042 Aspartyl-tRNA synthetase signature 474 490 4.7E-27 T 13-09-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 PANTHER PTHR22594 372 571 4.5E-250 T 13-09-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 Pfam PF01336 OB-fold nucleic acid binding domain 19 101 1.0E-16 T 13-09-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 Gene3D G3DSA:2.40.50.140 1 108 1.3E-39 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS22140 56d6795f5265d97d4549e31b08cf37aa 590 Gene3D G3DSA:3.30.1360.30 278 415 3.4E-46 T 13-09-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 THL1_RS17440 37ce4b57c6f32ed6b63b54d568e380c5 380 SUPERFAMILY SSF47203 239 376 1.01E-32 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS17440 37ce4b57c6f32ed6b63b54d568e380c5 380 Gene3D G3DSA:2.40.110.10 122 216 3.1E-16 T 13-09-2016 THL1_RS17440 37ce4b57c6f32ed6b63b54d568e380c5 380 PANTHER PTHR10909 1 349 8.3E-69 T 13-09-2016 THL1_RS17440 37ce4b57c6f32ed6b63b54d568e380c5 380 SUPERFAMILY SSF56645 1 227 5.24E-47 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS17440 37ce4b57c6f32ed6b63b54d568e380c5 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 9.4E-18 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS17440 37ce4b57c6f32ed6b63b54d568e380c5 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 244 364 2.0E-22 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS17440 37ce4b57c6f32ed6b63b54d568e380c5 380 PANTHER PTHR10909:SF341 1 349 8.3E-69 T 13-09-2016 THL1_RS17440 37ce4b57c6f32ed6b63b54d568e380c5 380 Gene3D G3DSA:1.20.140.10 217 371 9.5E-31 T 13-09-2016 THL1_RS17440 37ce4b57c6f32ed6b63b54d568e380c5 380 Gene3D G3DSA:1.10.540.10 1 118 5.3E-21 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS17440 37ce4b57c6f32ed6b63b54d568e380c5 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 215 8.9E-13 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS27215 c6ddb76e6b1e1f1a28168da41f0f0734 958 Pfam PF02347 Glycine cleavage system P-protein 18 441 4.9E-176 T 13-09-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 THL1_RS27215 c6ddb76e6b1e1f1a28168da41f0f0734 958 Pfam PF02347 Glycine cleavage system P-protein 478 729 7.9E-6 T 13-09-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 THL1_RS27215 c6ddb76e6b1e1f1a28168da41f0f0734 958 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 10 956 25.741 T 13-09-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2 THL1_RS27215 c6ddb76e6b1e1f1a28168da41f0f0734 958 SUPERFAMILY SSF53383 929 951 1.45E-95 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS27215 c6ddb76e6b1e1f1a28168da41f0f0734 958 SUPERFAMILY SSF53383 477 887 1.45E-95 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS27215 c6ddb76e6b1e1f1a28168da41f0f0734 958 SUPERFAMILY SSF53383 19 437 1.38E-96 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS27215 c6ddb76e6b1e1f1a28168da41f0f0734 958 PANTHER PTHR11773:SF1 6 958 0.0 T 13-09-2016 THL1_RS27215 c6ddb76e6b1e1f1a28168da41f0f0734 958 PANTHER PTHR11773 6 958 0.0 T 13-09-2016 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 THL1_RS27215 c6ddb76e6b1e1f1a28168da41f0f0734 958 Gene3D G3DSA:3.40.640.10 89 305 2.3E-11 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS27215 c6ddb76e6b1e1f1a28168da41f0f0734 958 Gene3D G3DSA:3.40.640.10 503 739 1.4E-40 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS27215 c6ddb76e6b1e1f1a28168da41f0f0734 958 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 19 950 0.0 T 13-09-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2 THL1_RS03535 f8dc4b0bebd3dd02ce4aa79c3de6a9e9 99 Gene3D G3DSA:3.30.70.330 5 97 5.4E-33 T 13-09-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 THL1_RS03535 f8dc4b0bebd3dd02ce4aa79c3de6a9e9 99 PANTHER PTHR11620 7 95 1.3E-30 T 13-09-2016 THL1_RS03535 f8dc4b0bebd3dd02ce4aa79c3de6a9e9 99 Pfam PF00276 Ribosomal protein L23 8 94 9.6E-31 T 13-09-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 THL1_RS03535 f8dc4b0bebd3dd02ce4aa79c3de6a9e9 99 SUPERFAMILY SSF54189 1 91 7.91E-30 T 13-09-2016 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03535 f8dc4b0bebd3dd02ce4aa79c3de6a9e9 99 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 7 97 22.042 T 13-09-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 THL1_RS20150 b2dc4415d27ac8b42101725dd1e6277a 412 Pfam PF08281 Sigma-70, region 4 113 164 3.7E-8 T 13-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS20150 b2dc4415d27ac8b42101725dd1e6277a 412 Gene3D G3DSA:1.10.10.10 105 166 4.3E-13 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20150 b2dc4415d27ac8b42101725dd1e6277a 412 SUPERFAMILY SSF88946 8 94 2.63E-12 T 13-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS20150 b2dc4415d27ac8b42101725dd1e6277a 412 Gene3D G3DSA:1.25.40.10 203 245 3.2E-4 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS20150 b2dc4415d27ac8b42101725dd1e6277a 412 PANTHER PTHR30173:SF7 1 382 1.9E-207 T 13-09-2016 THL1_RS20150 b2dc4415d27ac8b42101725dd1e6277a 412 Gene3D G3DSA:1.25.40.10 265 319 2.7E-4 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS20150 b2dc4415d27ac8b42101725dd1e6277a 412 Gene3D G3DSA:1.25.40.10 362 394 2.7E-4 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS20150 b2dc4415d27ac8b42101725dd1e6277a 412 SUPERFAMILY SSF88659 103 166 1.36E-10 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS20150 b2dc4415d27ac8b42101725dd1e6277a 412 Pfam PF04542 Sigma-70 region 2 14 80 5.6E-9 T 13-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS20150 b2dc4415d27ac8b42101725dd1e6277a 412 Gene3D G3DSA:1.10.1740.10 4 100 7.9E-11 T 13-09-2016 THL1_RS20150 b2dc4415d27ac8b42101725dd1e6277a 412 PANTHER PTHR30173 1 382 1.9E-207 T 13-09-2016 THL1_RS20150 b2dc4415d27ac8b42101725dd1e6277a 412 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 166 5.0E-12 T 13-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS23325 92c4c76a71a428eb47cdd51cac0ebf48 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 1.7E-15 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS23325 92c4c76a71a428eb47cdd51cac0ebf48 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 6.8E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS23325 92c4c76a71a428eb47cdd51cac0ebf48 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 6.8E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS23325 92c4c76a71a428eb47cdd51cac0ebf48 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 6.8E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS23325 92c4c76a71a428eb47cdd51cac0ebf48 298 Gene3D G3DSA:1.10.10.10 3 85 3.3E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS23325 92c4c76a71a428eb47cdd51cac0ebf48 298 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 2 292 3.5E-113 T 13-09-2016 IPR017685 HTH-type transcriptional regulator ArgP THL1_RS23325 92c4c76a71a428eb47cdd51cac0ebf48 298 Pfam PF03466 LysR substrate binding domain 92 287 9.1E-13 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS23325 92c4c76a71a428eb47cdd51cac0ebf48 298 SUPERFAMILY SSF46785 2 110 4.99E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS23325 92c4c76a71a428eb47cdd51cac0ebf48 298 SUPERFAMILY SSF53850 85 290 7.06E-21 T 13-09-2016 THL1_RS23325 92c4c76a71a428eb47cdd51cac0ebf48 298 PANTHER PTHR30579 1 293 2.6E-121 T 13-09-2016 THL1_RS23325 92c4c76a71a428eb47cdd51cac0ebf48 298 PANTHER PTHR30579:SF2 1 293 2.6E-121 T 13-09-2016 THL1_RS23325 92c4c76a71a428eb47cdd51cac0ebf48 298 Hamap MF_00513 HTH-type transcriptional regulator ArgP [argP]. 1 295 49.789 T 13-09-2016 IPR023490 HTH-type transcriptional regulator ArgP, Gammaproteobacteria THL1_RS23325 92c4c76a71a428eb47cdd51cac0ebf48 298 Gene3D G3DSA:3.40.190.10 92 197 2.9E-38 T 13-09-2016 THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 SUPERFAMILY SSF50447 151 299 6.13E-31 T 13-09-2016 IPR009000 Translation protein, beta-barrel domain THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 SUPERFAMILY SSF54980 398 512 8.63E-26 T 13-09-2016 IPR009022 Elongation factor G, III-V domain THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 5 599 9.0E-283 T 13-09-2016 IPR006298 GTP-binding protein TypA GO:0005525 THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 Gene3D G3DSA:3.40.50.300 3 205 1.0E-67 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 PANTHER PTHR23115 3 602 2.9E-297 T 13-09-2016 THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 Gene3D G3DSA:2.40.50.250 483 577 3.3E-37 T 13-09-2016 THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 13-09-2016 IPR031157 Tr-type G domain, conserved site THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 SUPERFAMILY SSF54980 302 387 3.56E-15 T 13-09-2016 IPR009022 Elongation factor G, III-V domain THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 Pfam PF00679 Elongation factor G C-terminus 397 477 7.9E-22 T 13-09-2016 IPR000640 Translation elongation factor EFG, V domain THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 Gene3D G3DSA:3.30.70.240 401 478 1.4E-30 T 13-09-2016 IPR000640 Translation elongation factor EFG, V domain THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 Gene3D G3DSA:3.30.70.870 303 400 9.1E-38 T 13-09-2016 THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 Pfam PF03144 Elongation factor Tu domain 2 219 289 1.8E-9 T 13-09-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 Gene3D G3DSA:2.40.30.10 206 302 2.4E-24 T 13-09-2016 THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 SUPERFAMILY SSF52540 3 219 4.76E-60 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 Pfam PF00009 Elongation factor Tu GTP binding domain 4 195 6.6E-58 T 13-09-2016 THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 PRINTS PR00315 GTP-binding elongation factor signature 87 98 1.1E-14 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 PRINTS PR00315 GTP-binding elongation factor signature 51 59 1.1E-14 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 PRINTS PR00315 GTP-binding elongation factor signature 71 81 1.1E-14 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 PRINTS PR00315 GTP-binding elongation factor signature 7 20 1.1E-14 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 PRINTS PR00315 GTP-binding elongation factor signature 123 132 1.1E-14 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 PANTHER PTHR23115:SF14 3 602 2.9E-297 T 13-09-2016 IPR006298 GTP-binding protein TypA GO:0005525 THL1_RS26650 812f53b2d2b7079aab5cc5d5ebbe672d 605 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 134 4.6E-25 T 13-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 SUPERFAMILY SSF100920 384 539 6.8E-60 T 13-09-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 SUPERFAMILY SSF53067 4 183 6.26E-66 T 13-09-2016 THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 Gene3D G3DSA:3.30.420.40 193 229 3.3E-34 T 13-09-2016 THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 Gene3D G3DSA:3.30.420.40 319 361 3.3E-34 T 13-09-2016 THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 Gene3D G3DSA:3.30.420.40 4 52 5.3E-65 T 13-09-2016 THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 Gene3D G3DSA:3.30.420.40 119 192 5.3E-65 T 13-09-2016 THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 192 205 - T 13-09-2016 IPR018181 Heat shock protein 70, conserved site THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 633 36.839 T 13-09-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 PRINTS PR00301 70kDa heat shock protein signature 334 350 2.3E-80 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 PRINTS PR00301 70kDa heat shock protein signature 365 385 2.3E-80 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.3E-80 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 PRINTS PR00301 70kDa heat shock protein signature 388 407 2.3E-80 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.3E-80 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 PRINTS PR00301 70kDa heat shock protein signature 138 158 2.3E-80 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.3E-80 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 PRINTS PR00301 70kDa heat shock protein signature 469 485 2.3E-80 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 PRINTS PR00301 70kDa heat shock protein signature 198 208 2.3E-80 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 PANTHER PTHR19375:SF173 2 637 0.0 T 13-09-2016 THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 PANTHER PTHR19375 2 637 0.0 T 13-09-2016 THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 Gene3D G3DSA:3.90.640.10 230 315 3.2E-31 T 13-09-2016 THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 Gene3D G3DSA:3.30.30.30 53 108 3.9E-28 T 13-09-2016 THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 SUPERFAMILY SSF53067 187 382 2.66E-69 T 13-09-2016 THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 13-09-2016 IPR018181 Heat shock protein 70, conserved site THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 Pfam PF00012 Hsp70 protein 4 603 1.8E-264 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 Gene3D G3DSA:1.20.1270.10 532 603 1.8E-26 T 13-09-2016 IPR029048 Heat shock protein 70kD, C-terminal domain THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 603 3.5E-289 T 13-09-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 337 351 - T 13-09-2016 IPR018181 Heat shock protein 70, conserved site THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 SUPERFAMILY SSF100934 507 603 4.84E-23 T 13-09-2016 IPR029048 Heat shock protein 70kD, C-terminal domain THL1_RS24490 9a511fa3ee9fd72bafe09735ff23f417 637 Gene3D G3DSA:2.60.34.10 390 531 5.1E-70 T 13-09-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain THL1_RS04910 696e0f729052f60ebd6050584403ce02 178 Pfam PF12019 Type II transport protein GspH 57 165 1.9E-19 T 13-09-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 THL1_RS04910 696e0f729052f60ebd6050584403ce02 178 Gene3D G3DSA:3.30.700.10 22 90 1.1E-8 T 13-09-2016 THL1_RS04910 696e0f729052f60ebd6050584403ce02 178 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 20 42 1.7E-7 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS04910 696e0f729052f60ebd6050584403ce02 178 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 20 40 - T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS04910 696e0f729052f60ebd6050584403ce02 178 SUPERFAMILY SSF54523 22 124 8.63E-22 T 13-09-2016 THL1_RS04910 696e0f729052f60ebd6050584403ce02 178 Pfam PF13633 Prokaryotic N-terminal methylation site 20 45 4.2E-9 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS01110 f9bd351acb1b16c6e6d32fdd1a8782d3 259 SMART SM00382 44 231 1.4E-17 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS01110 f9bd351acb1b16c6e6d32fdd1a8782d3 259 SUPERFAMILY SSF52540 22 253 3.47E-77 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01110 f9bd351acb1b16c6e6d32fdd1a8782d3 259 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS01110 f9bd351acb1b16c6e6d32fdd1a8782d3 259 Pfam PF00005 ABC transporter 35 183 2.2E-34 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS01110 f9bd351acb1b16c6e6d32fdd1a8782d3 259 PANTHER PTHR24220:SF474 21 258 2.0E-150 T 13-09-2016 THL1_RS01110 f9bd351acb1b16c6e6d32fdd1a8782d3 259 PIRSF PIRSF039085 16 259 1.8E-107 T 13-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 THL1_RS01110 f9bd351acb1b16c6e6d32fdd1a8782d3 259 Gene3D G3DSA:3.40.50.300 19 254 6.7E-82 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01110 f9bd351acb1b16c6e6d32fdd1a8782d3 259 PANTHER PTHR24220 21 258 2.0E-150 T 13-09-2016 THL1_RS04345 96b10574efb4202e2017517fb6740915 209 PANTHER PTHR20857:SF15 6 200 7.4E-54 T 13-09-2016 THL1_RS04345 96b10574efb4202e2017517fb6740915 209 SUPERFAMILY SSF51391 3 199 1.18E-59 T 13-09-2016 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 THL1_RS04345 96b10574efb4202e2017517fb6740915 209 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 4 207 24.914 T 13-09-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 THL1_RS04345 96b10574efb4202e2017517fb6740915 209 Gene3D G3DSA:3.20.20.70 4 207 2.7E-61 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS04345 96b10574efb4202e2017517fb6740915 209 PANTHER PTHR20857 6 200 7.4E-54 T 13-09-2016 THL1_RS04345 96b10574efb4202e2017517fb6740915 209 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 6 196 1.1E-59 T 13-09-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 THL1_RS04345 96b10574efb4202e2017517fb6740915 209 Pfam PF02581 Thiamine monophosphate synthase/TENI 6 186 5.3E-55 T 13-09-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 THL1_RS01075 c5ce7ad712969b80a00d1cd2f5e5ca0a 612 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 507 518 - T 13-09-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS01075 c5ce7ad712969b80a00d1cd2f5e5ca0a 612 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 13-09-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS01075 c5ce7ad712969b80a00d1cd2f5e5ca0a 612 PANTHER PTHR21000:SF11 1 369 0.0 T 13-09-2016 THL1_RS01075 c5ce7ad712969b80a00d1cd2f5e5ca0a 612 Pfam PF00920 Dehydratase family 34 603 1.7E-219 T 13-09-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS01075 c5ce7ad712969b80a00d1cd2f5e5ca0a 612 SUPERFAMILY SSF143975 3 418 2.35E-137 T 13-09-2016 THL1_RS01075 c5ce7ad712969b80a00d1cd2f5e5ca0a 612 PANTHER PTHR21000 1 369 0.0 T 13-09-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS01075 c5ce7ad712969b80a00d1cd2f5e5ca0a 612 PANTHER PTHR21000 404 611 0.0 T 13-09-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS01075 c5ce7ad712969b80a00d1cd2f5e5ca0a 612 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 606 44.954 T 13-09-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS01075 c5ce7ad712969b80a00d1cd2f5e5ca0a 612 SUPERFAMILY SSF52016 419 606 5.41E-60 T 13-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THL1_RS01075 c5ce7ad712969b80a00d1cd2f5e5ca0a 612 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 606 5.3E-252 T 13-09-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS01075 c5ce7ad712969b80a00d1cd2f5e5ca0a 612 PANTHER PTHR21000:SF11 404 611 0.0 T 13-09-2016 THL1_RS16515 491cdd0d90c8016d0c23b3ad0c1eabcb 499 Gene3D G3DSA:3.40.605.10 19 279 1.0E-98 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS16515 491cdd0d90c8016d0c23b3ad0c1eabcb 499 Pfam PF00171 Aldehyde dehydrogenase family 29 494 5.0E-174 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS16515 491cdd0d90c8016d0c23b3ad0c1eabcb 499 PANTHER PTHR11699:SF210 1 498 2.7E-249 T 13-09-2016 THL1_RS16515 491cdd0d90c8016d0c23b3ad0c1eabcb 499 SUPERFAMILY SSF53720 13 497 2.88E-167 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS16515 491cdd0d90c8016d0c23b3ad0c1eabcb 499 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 266 273 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS16515 491cdd0d90c8016d0c23b3ad0c1eabcb 499 PANTHER PTHR11699 1 498 2.7E-249 T 13-09-2016 THL1_RS16515 491cdd0d90c8016d0c23b3ad0c1eabcb 499 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS16515 491cdd0d90c8016d0c23b3ad0c1eabcb 499 Gene3D G3DSA:3.40.309.10 280 468 1.5E-68 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 Pfam PF01039 Carboxyl transferase domain 604 1078 2.3E-74 T 13-09-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 SUPERFAMILY SSF51230 482 557 2.36E-16 T 13-09-2016 IPR011053 Single hybrid motif THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 SMART SM00878 340 450 3.9E-39 T 13-09-2016 IPR005482 Biotin carboxylase, C-terminal THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 PANTHER PTHR18866 1 453 3.0E-211 T 13-09-2016 THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 SUPERFAMILY SSF52096 844 1081 2.63E-59 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 Gene3D G3DSA:2.40.50.100 490 557 5.6E-17 T 13-09-2016 THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 SUPERFAMILY SSF52096 582 837 1.39E-48 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 Gene3D G3DSA:3.30.1490.20 129 201 6.3E-20 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 PANTHER PTHR18866:SF103 1 453 3.0E-211 T 13-09-2016 THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 Gene3D G3DSA:3.40.50.20 1 128 6.3E-43 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 SUPERFAMILY SSF56059 82 328 7.6E-58 T 13-09-2016 THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 Gene3D G3DSA:3.30.470.20 204 454 1.9E-77 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 Gene3D G3DSA:3.90.226.10 833 1080 3.3E-53 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 323 2.4E-57 T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 109 6.3E-39 T 13-09-2016 IPR005481 Biotin carboxylase-like, N-terminal domain THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 Gene3D G3DSA:3.90.226.10 594 832 1.3E-42 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 Pfam PF02785 Biotin carboxylase C-terminal domain 340 451 5.3E-29 T 13-09-2016 IPR005482 Biotin carboxylase, C-terminal THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 Pfam PF00364 Biotin-requiring enzyme 492 556 6.0E-12 T 13-09-2016 IPR000089 Biotin/lipoyl attachment THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 SUPERFAMILY SSF51246 335 455 3.77E-29 T 13-09-2016 IPR011054 Rudiment single hybrid motif THL1_RS20525 a48abf1f589e60b637eb24fbff4b6870 1096 SUPERFAMILY SSF52440 1 111 6.69E-39 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS06870 d51e2c803e425f637c486a6d4d75a957 110 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 4 106 1.7E-30 T 13-09-2016 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 THL1_RS06870 d51e2c803e425f637c486a6d4d75a957 110 PANTHER PTHR36116 1 110 1.6E-47 T 13-09-2016 THL1_RS06870 d51e2c803e425f637c486a6d4d75a957 110 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 1 106 23.506 T 13-09-2016 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 THL1_RS06870 d51e2c803e425f637c486a6d4d75a957 110 SUPERFAMILY SSF103481 6 106 2.35E-8 T 13-09-2016 THL1_RS06870 d51e2c803e425f637c486a6d4d75a957 110 PANTHER PTHR36116:SF1 1 110 1.6E-47 T 13-09-2016 THL1_RS06370 305d4e09217714d728e26bffa02a94c2 342 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 255 1.2E-33 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS06370 305d4e09217714d728e26bffa02a94c2 342 PANTHER PTHR30085 1 311 4.1E-189 T 13-09-2016 THL1_RS06370 305d4e09217714d728e26bffa02a94c2 342 SUPERFAMILY SSF53850 28 256 2.24E-50 T 13-09-2016 THL1_RS06370 305d4e09217714d728e26bffa02a94c2 342 Gene3D G3DSA:3.40.190.10 34 127 1.7E-19 T 13-09-2016 THL1_RS06370 305d4e09217714d728e26bffa02a94c2 342 Gene3D G3DSA:3.40.190.10 226 251 1.7E-19 T 13-09-2016 THL1_RS06370 305d4e09217714d728e26bffa02a94c2 342 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 60 73 - T 13-09-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 THL1_RS06370 305d4e09217714d728e26bffa02a94c2 342 PANTHER PTHR30085:SF5 1 311 4.1E-189 T 13-09-2016 THL1_RS06370 305d4e09217714d728e26bffa02a94c2 342 SMART SM00062 37 266 3.2E-59 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS06370 305d4e09217714d728e26bffa02a94c2 342 Gene3D G3DSA:3.40.190.10 128 225 2.8E-16 T 13-09-2016 THL1_RS12710 dfffd1f3aa6911459844f3fd61c9fc38 323 Gene3D G3DSA:3.30.450.20 96 248 9.3E-21 T 13-09-2016 THL1_RS12710 dfffd1f3aa6911459844f3fd61c9fc38 323 PANTHER PTHR32089 259 322 8.4E-34 T 13-09-2016 THL1_RS12710 dfffd1f3aa6911459844f3fd61c9fc38 323 Gene3D G3DSA:1.10.287.950 253 322 7.0E-32 T 13-09-2016 THL1_RS12710 dfffd1f3aa6911459844f3fd61c9fc38 323 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 241 321 1.5E-29 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS12710 dfffd1f3aa6911459844f3fd61c9fc38 323 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 143 245 5.5E-10 T 13-09-2016 IPR000014 PAS domain THL1_RS12710 dfffd1f3aa6911459844f3fd61c9fc38 323 SMART SM00086 197 239 6.2E-4 T 13-09-2016 IPR001610 PAC motif THL1_RS12710 dfffd1f3aa6911459844f3fd61c9fc38 323 SUPERFAMILY SSF55785 140 241 9.77E-19 T 13-09-2016 IPR000014 PAS domain THL1_RS12710 dfffd1f3aa6911459844f3fd61c9fc38 323 PANTHER PTHR32089:SF34 259 322 8.4E-34 T 13-09-2016 THL1_RS12710 dfffd1f3aa6911459844f3fd61c9fc38 323 Pfam PF08447 PAS fold 143 232 9.0E-22 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS12710 dfffd1f3aa6911459844f3fd61c9fc38 323 SUPERFAMILY SSF58104 251 321 1.44E-36 T 13-09-2016 THL1_RS17070 4ceded14a2706427438c0097b3644694 379 Gene3D G3DSA:1.20.1250.20 185 361 2.3E-8 T 13-09-2016 THL1_RS17070 4ceded14a2706427438c0097b3644694 379 Pfam PF07690 Major Facilitator Superfamily 2 294 1.1E-31 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS17070 4ceded14a2706427438c0097b3644694 379 Gene3D G3DSA:1.20.1250.20 1 168 3.5E-20 T 13-09-2016 THL1_RS17070 4ceded14a2706427438c0097b3644694 379 PANTHER PTHR23501:SF4 4 335 5.3E-54 T 13-09-2016 THL1_RS17070 4ceded14a2706427438c0097b3644694 379 PANTHER PTHR23501 4 335 5.3E-54 T 13-09-2016 THL1_RS17070 4ceded14a2706427438c0097b3644694 379 SUPERFAMILY SSF103473 2 369 1.44E-42 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS20955 9cd62d0a65bcdb46e1651a41bc78d511 419 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 193 382 5.5E-15 T 13-09-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 THL1_RS20955 9cd62d0a65bcdb46e1651a41bc78d511 419 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 84 107 - T 13-09-2016 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0016705|GO:0051537|GO:0055114 THL1_RS20955 9cd62d0a65bcdb46e1651a41bc78d511 419 SUPERFAMILY SSF55961 156 418 6.67E-47 T 13-09-2016 THL1_RS20955 9cd62d0a65bcdb46e1651a41bc78d511 419 Gene3D G3DSA:3.90.380.10 147 417 1.6E-60 T 13-09-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 THL1_RS20955 9cd62d0a65bcdb46e1651a41bc78d511 419 Pfam PF00355 Rieske [2Fe-2S] domain 41 123 3.1E-17 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS20955 9cd62d0a65bcdb46e1651a41bc78d511 419 SUPERFAMILY SSF50022 8 155 3.54E-46 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS20955 9cd62d0a65bcdb46e1651a41bc78d511 419 PANTHER PTHR21266:SF30 18 371 1.4E-74 T 13-09-2016 THL1_RS20955 9cd62d0a65bcdb46e1651a41bc78d511 419 Gene3D G3DSA:2.102.10.10 41 146 2.6E-20 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS20955 9cd62d0a65bcdb46e1651a41bc78d511 419 PANTHER PTHR21266 18 371 1.4E-74 T 13-09-2016 THL1_RS20955 9cd62d0a65bcdb46e1651a41bc78d511 419 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 98 118 8.2E-38 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS20955 9cd62d0a65bcdb46e1651a41bc78d511 419 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 26 51 8.2E-38 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS20955 9cd62d0a65bcdb46e1651a41bc78d511 419 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 56 71 8.2E-38 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS20955 9cd62d0a65bcdb46e1651a41bc78d511 419 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 182 204 8.2E-38 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS20955 9cd62d0a65bcdb46e1651a41bc78d511 419 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 140 166 8.2E-38 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS20955 9cd62d0a65bcdb46e1651a41bc78d511 419 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 77 97 8.2E-38 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS14340 871bfa56d0e1f1634a7ff1d72454aba0 459 PANTHER PTHR11699:SF28 8 458 1.6E-229 T 13-09-2016 THL1_RS14340 871bfa56d0e1f1634a7ff1d72454aba0 459 Gene3D G3DSA:3.40.605.10 9 245 4.5E-67 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS14340 871bfa56d0e1f1634a7ff1d72454aba0 459 Pfam PF00171 Aldehyde dehydrogenase family 8 454 1.1E-137 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS14340 871bfa56d0e1f1634a7ff1d72454aba0 459 PANTHER PTHR11699 8 458 1.6E-229 T 13-09-2016 THL1_RS14340 871bfa56d0e1f1634a7ff1d72454aba0 459 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 258 269 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS14340 871bfa56d0e1f1634a7ff1d72454aba0 459 SUPERFAMILY SSF53720 8 457 3.27E-138 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS14340 871bfa56d0e1f1634a7ff1d72454aba0 459 Gene3D G3DSA:3.40.309.10 246 434 3.7E-63 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.0E-39 T 13-09-2016 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 3.0E-39 T 13-09-2016 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 286 3.0E-39 T 13-09-2016 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 3.0E-39 T 13-09-2016 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 3.0E-39 T 13-09-2016 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 Gene3D G3DSA:3.30.390.30 341 471 4.0E-51 T 13-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 Gene3D G3DSA:3.50.50.60 3 147 1.5E-39 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 314 321 4.7E-82 T 13-09-2016 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 271 285 4.7E-82 T 13-09-2016 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 414 429 4.7E-82 T 13-09-2016 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 436 456 4.7E-82 T 13-09-2016 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 4.7E-82 T 13-09-2016 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 349 370 4.7E-82 T 13-09-2016 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 4.7E-82 T 13-09-2016 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 45 60 4.7E-82 T 13-09-2016 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 4.7E-82 T 13-09-2016 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 PIRSF PIRSF000350 1 471 5.0E-89 T 13-09-2016 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 46 56 - T 13-09-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 353 462 6.3E-40 T 13-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 SUPERFAMILY SSF55424 349 473 1.19E-42 T 13-09-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 PANTHER PTHR22912:SF131 1 465 1.4E-273 T 13-09-2016 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 334 6.7E-70 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 Gene3D G3DSA:3.50.50.60 148 340 1.6E-51 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 472 6.8E-165 T 13-09-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 PANTHER PTHR22912 1 465 1.4E-273 T 13-09-2016 THL1_RS10880 21652834d489734a8a0c2e0dbdea98b5 478 SUPERFAMILY SSF51905 1 347 3.0E-62 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 SUPERFAMILY SSF54106 415 457 4.05E-11 T 13-09-2016 IPR018392 LysM domain THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 135 163 - T 13-09-2016 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 SUPERFAMILY SSF54106 481 525 7.85E-11 T 13-09-2016 IPR018392 LysM domain THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 PANTHER PTHR21666 57 457 5.9E-163 T 13-09-2016 THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 SMART SM00257 482 525 2.2E-9 T 13-09-2016 IPR018392 LysM domain THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 SMART SM00257 346 389 1.7E-12 T 13-09-2016 IPR018392 LysM domain THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 SMART SM00257 415 458 3.7E-14 T 13-09-2016 IPR018392 LysM domain THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 Pfam PF01464 Transglycosylase SLT domain 126 225 2.1E-27 T 13-09-2016 IPR008258 Transglycosylase SLT domain 1 THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 SUPERFAMILY SSF54106 345 390 5.75E-11 T 13-09-2016 IPR018392 LysM domain THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 Pfam PF01476 LysM domain 483 524 8.1E-9 T 13-09-2016 IPR018392 LysM domain THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 Pfam PF01476 LysM domain 416 457 1.3E-12 T 13-09-2016 IPR018392 LysM domain THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 Pfam PF01476 LysM domain 347 389 9.3E-13 T 13-09-2016 IPR018392 LysM domain THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 SUPERFAMILY SSF53955 115 274 1.48E-42 T 13-09-2016 IPR023346 Lysozyme-like domain THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 Gene3D G3DSA:3.10.350.10 414 457 5.8E-17 T 13-09-2016 IPR018392 LysM domain THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 Gene3D G3DSA:3.10.350.10 480 525 4.1E-16 T 13-09-2016 IPR018392 LysM domain THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 Gene3D G3DSA:3.10.350.10 344 390 5.3E-17 T 13-09-2016 IPR018392 LysM domain THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 PANTHER PTHR21666:SF206 57 457 5.9E-163 T 13-09-2016 THL1_RS17915 12139533533767e31b5bc7ffaf69a515 527 Gene3D G3DSA:1.10.530.10 113 273 7.5E-49 T 13-09-2016 THL1_RS19215 0fcdce18147c1aa8647376661653f4b8 232 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 6 231 38.284 T 13-09-2016 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|UniPathway: UPA00232 THL1_RS19215 0fcdce18147c1aa8647376661653f4b8 232 PANTHER PTHR10108:SF910 3 228 3.8E-143 T 13-09-2016 THL1_RS19215 0fcdce18147c1aa8647376661653f4b8 232 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 8 225 5.3E-87 T 13-09-2016 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|KEGG: 00340+2.1.1.22|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|UniPathway: UPA00232 THL1_RS19215 0fcdce18147c1aa8647376661653f4b8 232 Pfam PF13489 Methyltransferase domain 38 199 5.5E-27 T 13-09-2016 THL1_RS19215 0fcdce18147c1aa8647376661653f4b8 232 Gene3D G3DSA:3.40.50.150 19 217 2.7E-47 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS19215 0fcdce18147c1aa8647376661653f4b8 232 PANTHER PTHR10108 3 228 3.8E-143 T 13-09-2016 THL1_RS19215 0fcdce18147c1aa8647376661653f4b8 232 SUPERFAMILY SSF53335 12 226 5.27E-49 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS10125 bdb06a2341403e8c1fbef94e51491ca9 501 Pfam PF13522 Glutamine amidotransferase domain 63 208 7.1E-15 T 13-09-2016 THL1_RS10125 bdb06a2341403e8c1fbef94e51491ca9 501 Pfam PF00156 Phosphoribosyl transferase domain 277 393 6.8E-9 T 13-09-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 THL1_RS10125 bdb06a2341403e8c1fbef94e51491ca9 501 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 464 8.1E-162 T 13-09-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 THL1_RS10125 bdb06a2341403e8c1fbef94e51491ca9 501 PANTHER PTHR11907 1 478 2.8E-272 T 13-09-2016 THL1_RS10125 bdb06a2341403e8c1fbef94e51491ca9 501 Gene3D G3DSA:3.60.20.10 2 257 1.6E-61 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS10125 bdb06a2341403e8c1fbef94e51491ca9 501 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 466 44.37 T 13-09-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 THL1_RS10125 bdb06a2341403e8c1fbef94e51491ca9 501 Gene3D G3DSA:3.40.50.2020 271 444 4.0E-47 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS10125 bdb06a2341403e8c1fbef94e51491ca9 501 PANTHER PTHR11907:SF4 1 478 2.8E-272 T 13-09-2016 THL1_RS10125 bdb06a2341403e8c1fbef94e51491ca9 501 SUPERFAMILY SSF53271 250 483 7.87E-72 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS10125 bdb06a2341403e8c1fbef94e51491ca9 501 SUPERFAMILY SSF56235 2 257 1.72E-70 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS10125 bdb06a2341403e8c1fbef94e51491ca9 501 PIRSF PIRSF000485 1 481 4.9E-161 T 13-09-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 Pfam PF13188 PAS domain 208 246 0.057 T 13-09-2016 IPR000014 PAS domain THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 Pfam PF08448 PAS fold 329 437 8.4E-25 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 Pfam PF00512 His Kinase A (phospho-acceptor) domain 494 559 5.8E-9 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 Pfam PF00072 Response regulator receiver domain 738 849 3.5E-10 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 606 713 2.2E-17 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 PRINTS PR00344 Bacterial sensor protein C-terminal signature 639 653 3.4E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 PRINTS PR00344 Bacterial sensor protein C-terminal signature 674 692 3.4E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 PRINTS PR00344 Bacterial sensor protein C-terminal signature 698 711 3.4E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 Gene3D G3DSA:3.30.450.20 309 433 4.6E-21 T 13-09-2016 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 Gene3D G3DSA:3.30.565.10 562 715 3.9E-36 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 318 442 1.0E-13 T 13-09-2016 IPR000014 PAS domain THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 Gene3D G3DSA:3.40.50.2300 731 856 6.4E-16 T 13-09-2016 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 Gene3D G3DSA:3.30.450.20 197 308 7.2E-12 T 13-09-2016 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 Gene3D G3DSA:3.30.450.20 81 189 8.9E-11 T 13-09-2016 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 SUPERFAMILY SSF47384 479 559 3.34E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 SUPERFAMILY SSF55785 194 308 1.92E-9 T 13-09-2016 IPR000014 PAS domain THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 SUPERFAMILY SSF55874 550 712 1.15E-36 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 PANTHER PTHR24423 473 856 1.0E-259 T 13-09-2016 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 PANTHER PTHR24423 1 433 1.0E-259 T 13-09-2016 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 SMART SM00387 603 714 4.6E-26 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 PANTHER PTHR24423:SF479 473 856 1.0E-259 T 13-09-2016 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 PANTHER PTHR24423:SF479 1 433 1.0E-259 T 13-09-2016 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 Pfam PF12860 PAS fold 94 194 8.2E-13 T 13-09-2016 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 Pfam PF12860 PAS fold 276 314 1.1E-9 T 13-09-2016 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 SUPERFAMILY SSF55785 307 433 3.32E-23 T 13-09-2016 IPR000014 PAS domain THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 SMART SM00448 736 850 1.3E-8 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 SUPERFAMILY SSF55785 82 188 3.14E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 SMART SM00388 494 559 2.8E-10 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 SUPERFAMILY SSF52172 734 855 1.57E-16 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 SMART SM00091 322 388 0.33 T 13-09-2016 IPR000014 PAS domain THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 SMART SM00091 88 156 13.0 T 13-09-2016 IPR000014 PAS domain THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 SMART SM00091 207 272 0.44 T 13-09-2016 IPR000014 PAS domain THL1_RS14140 d779d50f6799ed94270017f278fd5042 856 Gene3D G3DSA:1.10.287.130 488 555 8.2E-8 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS10890 fcdf40700b27dd76f20da99880771a76 295 SUPERFAMILY SSF52210 123 287 1.3E-57 T 13-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 THL1_RS10890 fcdf40700b27dd76f20da99880771a76 295 Pfam PF00549 CoA-ligase 151 270 5.9E-22 T 13-09-2016 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 THL1_RS10890 fcdf40700b27dd76f20da99880771a76 295 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 287 1.3E-145 T 13-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 THL1_RS10890 fcdf40700b27dd76f20da99880771a76 295 PIRSF PIRSF001553 1 290 3.9E-134 T 13-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 THL1_RS10890 fcdf40700b27dd76f20da99880771a76 295 Gene3D G3DSA:3.40.50.720 2 119 1.0E-55 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10890 fcdf40700b27dd76f20da99880771a76 295 Pfam PF02629 CoA binding domain 6 99 3.1E-32 T 13-09-2016 IPR003781 CoA-binding GO:0048037 THL1_RS10890 fcdf40700b27dd76f20da99880771a76 295 SUPERFAMILY SSF51735 1 122 1.86E-43 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10890 fcdf40700b27dd76f20da99880771a76 295 Gene3D G3DSA:3.40.50.261 120 287 4.9E-78 T 13-09-2016 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|UniPathway: UPA00223 THL1_RS10890 fcdf40700b27dd76f20da99880771a76 295 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 13-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 THL1_RS10890 fcdf40700b27dd76f20da99880771a76 295 PANTHER PTHR11117 1 287 2.2E-198 T 13-09-2016 THL1_RS10890 fcdf40700b27dd76f20da99880771a76 295 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 1.0E-39 T 13-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 THL1_RS10890 fcdf40700b27dd76f20da99880771a76 295 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 1.0E-39 T 13-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 THL1_RS10890 fcdf40700b27dd76f20da99880771a76 295 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 1.0E-39 T 13-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 THL1_RS10890 fcdf40700b27dd76f20da99880771a76 295 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 1.0E-39 T 13-09-2016 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 THL1_RS10890 fcdf40700b27dd76f20da99880771a76 295 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 13-09-2016 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site THL1_RS10890 fcdf40700b27dd76f20da99880771a76 295 SMART SM00881 4 100 2.6E-38 T 13-09-2016 IPR003781 CoA-binding GO:0048037 THL1_RS06275 b1d17245561c17eb2b9be284beab959c 497 PIRSF PIRSF500217 1 497 1.6E-163 T 13-09-2016 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.-|UniPathway: UPA00286 THL1_RS06275 b1d17245561c17eb2b9be284beab959c 497 PANTHER PTHR13285:SF23 1 433 1.6E-113 T 13-09-2016 THL1_RS06275 b1d17245561c17eb2b9be284beab959c 497 PANTHER PTHR13285 1 433 1.6E-113 T 13-09-2016 THL1_RS06275 b1d17245561c17eb2b9be284beab959c 497 PIRSF PIRSF016636 1 497 9.5E-162 T 13-09-2016 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB THL1_RS06275 b1d17245561c17eb2b9be284beab959c 497 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 150 361 1.6E-23 T 13-09-2016 IPR004299 Membrane bound O-acyl transferase, MBOAT THL1_RS27195 49ca51edb33da530cf195163cd2f6b43 306 ProSitePatterns PS01270 Band 7 protein family signature. 134 162 - T 13-09-2016 IPR018080 Band 7/stomatin-like, conserved site THL1_RS27195 49ca51edb33da530cf195163cd2f6b43 306 PANTHER PTHR10264:SF27 6 299 1.0E-117 T 13-09-2016 THL1_RS27195 49ca51edb33da530cf195163cd2f6b43 306 SUPERFAMILY SSF117892 51 185 3.4E-39 T 13-09-2016 IPR001107 Band 7 domain THL1_RS27195 49ca51edb33da530cf195163cd2f6b43 306 PRINTS PR00721 Stomatin signature 173 194 4.0E-29 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS27195 49ca51edb33da530cf195163cd2f6b43 306 PRINTS PR00721 Stomatin signature 130 153 4.0E-29 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS27195 49ca51edb33da530cf195163cd2f6b43 306 PRINTS PR00721 Stomatin signature 75 96 4.0E-29 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS27195 49ca51edb33da530cf195163cd2f6b43 306 PRINTS PR00721 Stomatin signature 110 127 4.0E-29 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS27195 49ca51edb33da530cf195163cd2f6b43 306 PRINTS PR00721 Stomatin signature 154 172 4.0E-29 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS27195 49ca51edb33da530cf195163cd2f6b43 306 SMART SM00244 20 178 2.1E-55 T 13-09-2016 IPR001107 Band 7 domain THL1_RS27195 49ca51edb33da530cf195163cd2f6b43 306 Pfam PF01145 SPFH domain / Band 7 family 24 193 1.0E-31 T 13-09-2016 IPR001107 Band 7 domain THL1_RS27195 49ca51edb33da530cf195163cd2f6b43 306 PANTHER PTHR10264 6 299 1.0E-117 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS27195 49ca51edb33da530cf195163cd2f6b43 306 Pfam PF16200 C-terminal region of band_7 239 299 2.2E-9 T 13-09-2016 IPR032435 Band 7, C-terminal extension THL1_RS10645 2d0a2f053f6c84da0b796e48febf7f9b 235 PANTHER PTHR30055:SF73 4 171 4.6E-46 T 13-09-2016 THL1_RS10645 2d0a2f053f6c84da0b796e48febf7f9b 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 2.0E-15 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS10645 2d0a2f053f6c84da0b796e48febf7f9b 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 3.5E-11 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS10645 2d0a2f053f6c84da0b796e48febf7f9b 235 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 3.5E-11 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS10645 2d0a2f053f6c84da0b796e48febf7f9b 235 SUPERFAMILY SSF46689 4 75 2.41E-18 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS10645 2d0a2f053f6c84da0b796e48febf7f9b 235 SUPERFAMILY SSF48498 82 208 2.18E-39 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS10645 2d0a2f053f6c84da0b796e48febf7f9b 235 PANTHER PTHR30055 4 171 4.6E-46 T 13-09-2016 THL1_RS10645 2d0a2f053f6c84da0b796e48febf7f9b 235 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 53 - T 13-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site THL1_RS10645 2d0a2f053f6c84da0b796e48febf7f9b 235 Gene3D G3DSA:1.10.357.10 3 208 2.6E-43 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS12065 884ca6ccc7216d1f1e468f0178044111 76 Pfam PF10982 Protein of unknown function (DUF2789) 1 74 1.8E-26 T 13-09-2016 IPR021250 Protein of unknown function DUF2789 THL1_RS19810 83ee2bf4c68347ff8ae3278859ba5eee 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 2.1E-12 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS19810 83ee2bf4c68347ff8ae3278859ba5eee 216 Gene3D G3DSA:1.10.357.10 12 202 6.6E-43 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS19810 83ee2bf4c68347ff8ae3278859ba5eee 216 PANTHER PTHR30328 10 209 4.4E-38 T 13-09-2016 THL1_RS19810 83ee2bf4c68347ff8ae3278859ba5eee 216 SUPERFAMILY SSF48498 87 202 6.67E-19 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS19810 83ee2bf4c68347ff8ae3278859ba5eee 216 PANTHER PTHR30328:SF11 10 209 4.4E-38 T 13-09-2016 THL1_RS19810 83ee2bf4c68347ff8ae3278859ba5eee 216 SUPERFAMILY SSF46689 8 87 6.48E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19810 83ee2bf4c68347ff8ae3278859ba5eee 216 Pfam PF13977 Bacterial transcriptional repressor 89 201 1.1E-24 T 13-09-2016 THL1_RS11315 c2fe2a0a22d516f460557d6f44b65b08 183 PANTHER PTHR10681:SF87 1 181 7.2E-77 T 13-09-2016 THL1_RS11315 c2fe2a0a22d516f460557d6f44b65b08 183 Gene3D G3DSA:3.40.30.10 2 181 9.6E-61 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS11315 c2fe2a0a22d516f460557d6f44b65b08 183 Pfam PF00578 AhpC/TSA family 4 142 1.4E-32 T 13-09-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS11315 c2fe2a0a22d516f460557d6f44b65b08 183 PANTHER PTHR10681 1 181 7.2E-77 T 13-09-2016 THL1_RS11315 c2fe2a0a22d516f460557d6f44b65b08 183 PIRSF PIRSF000239 1 183 2.8E-49 T 13-09-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 THL1_RS11315 c2fe2a0a22d516f460557d6f44b65b08 183 SUPERFAMILY SSF52833 1 181 4.08E-53 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS12580 1e9e3d0fecd0f91a7f643f9bdac43798 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 241 1.1E-51 T 13-09-2016 THL1_RS12580 1e9e3d0fecd0f91a7f643f9bdac43798 245 PANTHER PTHR24322 155 191 7.1E-53 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12580 1e9e3d0fecd0f91a7f643f9bdac43798 245 PANTHER PTHR24322 10 137 7.1E-53 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12580 1e9e3d0fecd0f91a7f643f9bdac43798 245 Gene3D G3DSA:3.40.50.720 5 242 1.1E-72 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS12580 1e9e3d0fecd0f91a7f643f9bdac43798 245 SUPERFAMILY SSF51735 5 241 9.65E-71 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS12580 1e9e3d0fecd0f91a7f643f9bdac43798 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.8E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12580 1e9e3d0fecd0f91a7f643f9bdac43798 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.8E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12580 1e9e3d0fecd0f91a7f643f9bdac43798 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.8E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12580 1e9e3d0fecd0f91a7f643f9bdac43798 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 6.4E-36 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12580 1e9e3d0fecd0f91a7f643f9bdac43798 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 6.4E-36 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12580 1e9e3d0fecd0f91a7f643f9bdac43798 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 6.4E-36 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12580 1e9e3d0fecd0f91a7f643f9bdac43798 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 6.4E-36 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12580 1e9e3d0fecd0f91a7f643f9bdac43798 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.4E-36 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12580 1e9e3d0fecd0f91a7f643f9bdac43798 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.4E-36 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18750 a90644281563e5dedb54d6889adec600 896 SUPERFAMILY SSF53732 4 628 1.44E-223 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 Gene3D G3DSA:3.30.499.10 369 576 3.3E-61 T 13-09-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 Gene3D G3DSA:3.40.1060.10 250 367 1.3E-34 T 13-09-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 Gene3D G3DSA:3.30.499.10 28 249 1.1E-77 T 13-09-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 894 0.0 T 13-09-2016 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 ProSitePatterns PS01244 Aconitase family signature 2. 495 508 - T 13-09-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 SUPERFAMILY SSF52016 632 894 2.94E-89 T 13-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THL1_RS18750 a90644281563e5dedb54d6889adec600 896 PANTHER PTHR11670:SF1 418 652 0.0 T 13-09-2016 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 PANTHER PTHR11670:SF1 8 393 0.0 T 13-09-2016 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 PANTHER PTHR11670 752 896 0.0 T 13-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 ProSitePatterns PS00450 Aconitase family signature 1. 429 445 - T 13-09-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 PRINTS PR00415 Aconitase family signature 170 178 1.9E-41 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 PRINTS PR00415 Aconitase family signature 203 216 1.9E-41 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 PRINTS PR00415 Aconitase family signature 279 292 1.9E-41 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 PRINTS PR00415 Aconitase family signature 495 508 1.9E-41 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 PRINTS PR00415 Aconitase family signature 372 386 1.9E-41 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 PRINTS PR00415 Aconitase family signature 433 444 1.9E-41 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 PRINTS PR00415 Aconitase family signature 217 232 1.9E-41 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 PRINTS PR00415 Aconitase family signature 146 159 1.9E-41 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 PRINTS PR00415 Aconitase family signature 293 306 1.9E-41 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 Pfam PF00330 Aconitase family (aconitate hydratase) 76 564 2.1E-182 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 PANTHER PTHR11670:SF1 668 713 0.0 T 13-09-2016 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 PANTHER PTHR11670:SF1 752 896 0.0 T 13-09-2016 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 Gene3D G3DSA:3.20.19.10 638 894 1.4E-84 T 13-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THL1_RS18750 a90644281563e5dedb54d6889adec600 896 Pfam PF00694 Aconitase C-terminal domain 693 820 1.5E-49 T 13-09-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 PANTHER PTHR11670 418 652 0.0 T 13-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 PANTHER PTHR11670 668 713 0.0 T 13-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS18750 a90644281563e5dedb54d6889adec600 896 PANTHER PTHR11670 8 393 0.0 T 13-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS14100 21a5d4e5d8b0e1d01d1654fe77a97cf8 954 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 8 951 26.161 T 13-09-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2 THL1_RS14100 21a5d4e5d8b0e1d01d1654fe77a97cf8 954 Gene3D G3DSA:3.40.640.10 502 735 4.6E-41 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS14100 21a5d4e5d8b0e1d01d1654fe77a97cf8 954 Gene3D G3DSA:3.40.640.10 84 307 1.5E-13 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS14100 21a5d4e5d8b0e1d01d1654fe77a97cf8 954 PANTHER PTHR11773 1 953 0.0 T 13-09-2016 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 THL1_RS14100 21a5d4e5d8b0e1d01d1654fe77a97cf8 954 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 17 945 0.0 T 13-09-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2 THL1_RS14100 21a5d4e5d8b0e1d01d1654fe77a97cf8 954 SUPERFAMILY SSF53383 924 946 2.56E-106 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS14100 21a5d4e5d8b0e1d01d1654fe77a97cf8 954 SUPERFAMILY SSF53383 460 882 2.56E-106 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS14100 21a5d4e5d8b0e1d01d1654fe77a97cf8 954 PANTHER PTHR11773:SF1 1 953 0.0 T 13-09-2016 THL1_RS14100 21a5d4e5d8b0e1d01d1654fe77a97cf8 954 Pfam PF02347 Glycine cleavage system P-protein 459 734 3.0E-11 T 13-09-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 THL1_RS14100 21a5d4e5d8b0e1d01d1654fe77a97cf8 954 Pfam PF02347 Glycine cleavage system P-protein 17 441 4.4E-180 T 13-09-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 THL1_RS14100 21a5d4e5d8b0e1d01d1654fe77a97cf8 954 SUPERFAMILY SSF53383 17 442 7.72E-100 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS03610 9029e7bab7e791ebb346ed5167685f7d 166 Gene3D G3DSA:3.30.160.20 11 73 3.2E-28 T 13-09-2016 IPR014720 Double-stranded RNA-binding domain THL1_RS03610 9029e7bab7e791ebb346ed5167685f7d 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 89 158 7.9E-32 T 13-09-2016 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 THL1_RS03610 9029e7bab7e791ebb346ed5167685f7d 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 14 75 2.6E-27 T 13-09-2016 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 THL1_RS03610 9029e7bab7e791ebb346ed5167685f7d 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 29 61 - T 13-09-2016 IPR018192 Ribosomal protein S5, N-terminal, conserved site THL1_RS03610 9029e7bab7e791ebb346ed5167685f7d 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 11 164 4.8E-66 T 13-09-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 THL1_RS03610 9029e7bab7e791ebb346ed5167685f7d 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 164 34.075 T 13-09-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 THL1_RS03610 9029e7bab7e791ebb346ed5167685f7d 166 SUPERFAMILY SSF54211 81 160 9.36E-27 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS03610 9029e7bab7e791ebb346ed5167685f7d 166 SUPERFAMILY SSF54768 10 77 7.53E-23 T 13-09-2016 THL1_RS03610 9029e7bab7e791ebb346ed5167685f7d 166 Gene3D G3DSA:3.30.230.10 78 160 1.3E-32 T 13-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THL1_RS03610 9029e7bab7e791ebb346ed5167685f7d 166 PANTHER PTHR13718 10 165 1.4E-75 T 13-09-2016 IPR000851 Ribosomal protein S5 GO:0003735|GO:0005840|GO:0006412 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Gene3D G3DSA:2.40.50.100 719 797 1.2E-31 T 13-09-2016 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Pfam PF04565 RNA polymerase Rpb2, domain 3 518 585 6.5E-31 T 13-09-2016 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1357 12.322 T 13-09-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Gene3D G3DSA:3.90.1110.10 351 449 1.7E-66 T 13-09-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Gene3D G3DSA:3.90.1110.10 157 234 1.7E-66 T 13-09-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 PANTHER PTHR20856 345 730 0.0 T 13-09-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 PANTHER PTHR20856 1197 1357 0.0 T 13-09-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Gene3D G3DSA:2.40.50.150 1062 1076 5.8E-58 T 13-09-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Gene3D G3DSA:2.40.50.150 833 942 5.8E-58 T 13-09-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 PANTHER PTHR20856 1051 1145 0.0 T 13-09-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 PANTHER PTHR20856 748 935 0.0 T 13-09-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 PANTHER PTHR20856 5 234 0.0 T 13-09-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1080 1092 - T 13-09-2016 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Gene3D G3DSA:2.40.270.10 798 825 3.1E-88 T 13-09-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Gene3D G3DSA:2.40.270.10 1077 1257 3.1E-88 T 13-09-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Pfam PF04563 RNA polymerase beta subunit 26 504 2.5E-41 T 13-09-2016 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 PANTHER PTHR20856:SF20 1051 1145 0.0 T 13-09-2016 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 PANTHER PTHR20856:SF20 345 730 0.0 T 13-09-2016 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 PANTHER PTHR20856:SF20 1197 1357 0.0 T 13-09-2016 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 PANTHER PTHR20856:SF20 748 935 0.0 T 13-09-2016 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 PANTHER PTHR20856:SF20 5 234 0.0 T 13-09-2016 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1354 0.0 T 13-09-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Gene3D G3DSA:3.90.1100.10 450 596 2.8E-150 T 13-09-2016 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Gene3D G3DSA:3.90.1100.10 664 718 2.8E-150 T 13-09-2016 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Gene3D G3DSA:3.90.1100.10 20 155 2.8E-150 T 13-09-2016 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 SUPERFAMILY SSF64484 1056 1356 0.0 T 13-09-2016 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 SUPERFAMILY SSF64484 348 944 0.0 T 13-09-2016 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 SUPERFAMILY SSF64484 12 230 0.0 T 13-09-2016 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Pfam PF00562 RNA polymerase Rpb2, domain 6 722 1279 1.4E-160 T 13-09-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Pfam PF10385 RNA polymerase beta subunit external 1 domain 596 661 1.6E-20 T 13-09-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Pfam PF04561 RNA polymerase Rpb2, domain 2 362 459 2.6E-15 T 13-09-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Pfam PF04561 RNA polymerase Rpb2, domain 2 156 227 3.5E-7 T 13-09-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Pfam PF04560 RNA polymerase Rpb2, domain 7 1281 1356 4.2E-27 T 13-09-2016 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 THL1_RS03490 fa3d85f60b9d201b1f04b9d3ab31a7f6 1357 Gene3D G3DSA:2.30.150.10 597 661 1.3E-22 T 13-09-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS00515 33c49cb4eecb826da971de6bb10d961f 104 PANTHER PTHR10160:SF19 10 95 6.3E-32 T 13-09-2016 THL1_RS00515 33c49cb4eecb826da971de6bb10d961f 104 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 11 94 1.5E-35 T 13-09-2016 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2 THL1_RS00515 33c49cb4eecb826da971de6bb10d961f 104 PANTHER PTHR10160 10 95 6.3E-32 T 13-09-2016 THL1_RS03265 b9667563945c8aa992eed9bac15580d3 236 Pfam PF09347 Domain of unknown function (DUF1989) 45 209 1.2E-52 T 13-09-2016 IPR018959 Domain of unknown function DUF1989 THL1_RS03265 b9667563945c8aa992eed9bac15580d3 236 PANTHER PTHR31527:SF0 1 234 2.2E-53 T 13-09-2016 THL1_RS03265 b9667563945c8aa992eed9bac15580d3 236 PANTHER PTHR31527 1 234 2.2E-53 T 13-09-2016 THL1_RS24385 76f80c8faac59af97eedf110459635de 305 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 242 1.2E-21 T 13-09-2016 IPR032819 tRNA pseudouridylate synthase B, C-terminal THL1_RS24385 76f80c8faac59af97eedf110459635de 305 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 246 302 2.4E-19 T 13-09-2016 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS24385 76f80c8faac59af97eedf110459635de 305 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 12 219 2.9E-82 T 13-09-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS24385 76f80c8faac59af97eedf110459635de 305 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 11 302 19.204 T 13-09-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS24385 76f80c8faac59af97eedf110459635de 305 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 33 180 4.1E-57 T 13-09-2016 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 THL1_RS24385 76f80c8faac59af97eedf110459635de 305 SUPERFAMILY SSF88697 245 303 8.45E-14 T 13-09-2016 IPR015947 PUA-like domain THL1_RS24385 76f80c8faac59af97eedf110459635de 305 SUPERFAMILY SSF55120 11 241 3.17E-82 T 13-09-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS24385 76f80c8faac59af97eedf110459635de 305 PANTHER PTHR13767 2 302 4.6E-134 T 13-09-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS24385 76f80c8faac59af97eedf110459635de 305 PANTHER PTHR13767:SF2 2 302 4.6E-134 T 13-09-2016 THL1_RS24385 76f80c8faac59af97eedf110459635de 305 Gene3D G3DSA:2.30.130.10 244 303 7.2E-26 T 13-09-2016 IPR015947 PUA-like domain THL1_RS25960 ef28ef7dfaa6560eeea4309c0acb3558 174 Pfam PF13975 gag-polyprotein putative aspartyl protease 68 156 1.8E-24 T 13-09-2016 THL1_RS25960 ef28ef7dfaa6560eeea4309c0acb3558 174 PANTHER PTHR41535:SF1 1 174 2.9E-43 T 13-09-2016 THL1_RS25960 ef28ef7dfaa6560eeea4309c0acb3558 174 TIGRFAM TIGR02281 clan_AA_DTGA: clan AA aspartic protease, TIGR02281 family 54 170 1.4E-31 T 13-09-2016 IPR011969 Clan AA aspartic peptidase, C-terminal THL1_RS25960 ef28ef7dfaa6560eeea4309c0acb3558 174 PANTHER PTHR41535 1 174 2.9E-43 T 13-09-2016 THL1_RS25960 ef28ef7dfaa6560eeea4309c0acb3558 174 SUPERFAMILY SSF50630 58 160 4.96E-19 T 13-09-2016 IPR021109 Aspartic peptidase domain THL1_RS07280 7bac95f12c26ad1605f83b1282d447b3 187 Gene3D G3DSA:3.90.79.10 40 168 1.7E-37 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS07280 7bac95f12c26ad1605f83b1282d447b3 187 Pfam PF00293 NUDIX domain 45 157 2.7E-19 T 13-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 THL1_RS07280 7bac95f12c26ad1605f83b1282d447b3 187 PANTHER PTHR22769:SF17 5 169 3.4E-49 T 13-09-2016 THL1_RS07280 7bac95f12c26ad1605f83b1282d447b3 187 ProSitePatterns PS00893 Nudix box signature. 74 95 - T 13-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THL1_RS07280 7bac95f12c26ad1605f83b1282d447b3 187 PRINTS PR00502 NUDIX hydrolase family signature 83 98 6.5E-8 T 13-09-2016 IPR020476 NUDIX hydrolase THL1_RS07280 7bac95f12c26ad1605f83b1282d447b3 187 PRINTS PR00502 NUDIX hydrolase family signature 69 83 6.5E-8 T 13-09-2016 IPR020476 NUDIX hydrolase THL1_RS07280 7bac95f12c26ad1605f83b1282d447b3 187 Pfam PF14803 Nudix N-terminal 5 39 8.0E-14 T 13-09-2016 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.-+3.6.1.13|KEGG: 00332+3.6.1.-|KEGG: 00740+3.6.1.18|KEGG: 00790+3.6.1.- THL1_RS07280 7bac95f12c26ad1605f83b1282d447b3 187 PANTHER PTHR22769 5 169 3.4E-49 T 13-09-2016 THL1_RS07280 7bac95f12c26ad1605f83b1282d447b3 187 Gene3D G3DSA:2.20.70.10 5 39 1.3E-12 T 13-09-2016 THL1_RS07280 7bac95f12c26ad1605f83b1282d447b3 187 SUPERFAMILY SSF55811 5 166 1.62E-42 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS04490 c1c320b9c15e210ad7f0180b66bdb34a 188 SUPERFAMILY SSF52499 8 185 3.01E-44 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS04490 c1c320b9c15e210ad7f0180b66bdb34a 188 PANTHER PTHR11080:SF16 9 183 1.5E-58 T 13-09-2016 THL1_RS04490 c1c320b9c15e210ad7f0180b66bdb34a 188 PANTHER PTHR11080 9 183 1.5E-58 T 13-09-2016 THL1_RS04490 c1c320b9c15e210ad7f0180b66bdb34a 188 Pfam PF00857 Isochorismatase family 9 178 3.7E-32 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS04490 c1c320b9c15e210ad7f0180b66bdb34a 188 Gene3D G3DSA:3.40.50.850 4 186 2.8E-45 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS28185 5455251d98e272a2a3ca2703c609c73f 601 PANTHER PTHR18866:SF109 1 600 1.3E-251 T 13-09-2016 THL1_RS28185 5455251d98e272a2a3ca2703c609c73f 601 Gene3D G3DSA:3.20.20.70 1 283 1.8E-118 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS28185 5455251d98e272a2a3ca2703c609c73f 601 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 7 597 5.0E-258 T 13-09-2016 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 THL1_RS28185 5455251d98e272a2a3ca2703c609c73f 601 Gene3D G3DSA:2.40.50.100 530 600 2.3E-25 T 13-09-2016 THL1_RS28185 5455251d98e272a2a3ca2703c609c73f 601 Pfam PF02436 Conserved carboxylase domain 292 483 9.5E-57 T 13-09-2016 IPR003379 Carboxylase, conserved domain THL1_RS28185 5455251d98e272a2a3ca2703c609c73f 601 SUPERFAMILY SSF89000 297 447 9.81E-51 T 13-09-2016 THL1_RS28185 5455251d98e272a2a3ca2703c609c73f 601 Pfam PF00682 HMGL-like 4 268 4.9E-52 T 13-09-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 THL1_RS28185 5455251d98e272a2a3ca2703c609c73f 601 PANTHER PTHR18866 1 600 1.3E-251 T 13-09-2016 THL1_RS28185 5455251d98e272a2a3ca2703c609c73f 601 SUPERFAMILY SSF51230 529 600 1.22E-21 T 13-09-2016 IPR011053 Single hybrid motif THL1_RS28185 5455251d98e272a2a3ca2703c609c73f 601 Pfam PF00364 Biotin-requiring enzyme 535 600 8.3E-18 T 13-09-2016 IPR000089 Biotin/lipoyl attachment THL1_RS28185 5455251d98e272a2a3ca2703c609c73f 601 SUPERFAMILY SSF51569 1 300 1.83E-91 T 13-09-2016 THL1_RS07625 b37e6d12c413ffab04c547468f1fbc27 489 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 187 485 2.9E-117 T 13-09-2016 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS07625 b37e6d12c413ffab04c547468f1fbc27 489 SUPERFAMILY SSF55347 179 486 1.08E-114 T 13-09-2016 THL1_RS07625 b37e6d12c413ffab04c547468f1fbc27 489 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 13 184 3.6E-50 T 13-09-2016 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS07625 b37e6d12c413ffab04c547468f1fbc27 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 234 250 3.6E-49 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS07625 b37e6d12c413ffab04c547468f1fbc27 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 140 153 3.6E-49 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS07625 b37e6d12c413ffab04c547468f1fbc27 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 164 192 3.6E-49 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS07625 b37e6d12c413ffab04c547468f1fbc27 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 216 233 3.6E-49 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS07625 b37e6d12c413ffab04c547468f1fbc27 489 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 325 351 3.6E-49 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS07625 b37e6d12c413ffab04c547468f1fbc27 489 PIRSF PIRSF000110 1 488 3.6E-169 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS07625 b37e6d12c413ffab04c547468f1fbc27 489 Gene3D G3DSA:3.30.360.10 184 485 1.9E-124 T 13-09-2016 THL1_RS07625 b37e6d12c413ffab04c547468f1fbc27 489 SUPERFAMILY SSF51735 5 187 2.36E-50 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07625 b37e6d12c413ffab04c547468f1fbc27 489 PANTHER PTHR23429:SF0 7 488 2.0E-215 T 13-09-2016 THL1_RS07625 b37e6d12c413ffab04c547468f1fbc27 489 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 9 485 5.3E-175 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS07625 b37e6d12c413ffab04c547468f1fbc27 489 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 8 487 85.617 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS07625 b37e6d12c413ffab04c547468f1fbc27 489 Gene3D G3DSA:3.40.50.720 7 183 1.4E-52 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07625 b37e6d12c413ffab04c547468f1fbc27 489 PANTHER PTHR23429 7 488 2.0E-215 T 13-09-2016 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS07625 b37e6d12c413ffab04c547468f1fbc27 489 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 174 180 - T 13-09-2016 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268|UniPathway: UPA00115 THL1_RS10285 b2165d5891ff90e9e12eeccd912cdf0d 455 Gene3D G3DSA:2.50.20.10 341 451 6.9E-37 T 13-09-2016 THL1_RS10285 b2165d5891ff90e9e12eeccd912cdf0d 455 Gene3D G3DSA:2.50.20.10 160 308 6.9E-37 T 13-09-2016 THL1_RS10285 b2165d5891ff90e9e12eeccd912cdf0d 455 Pfam PF07044 Protein of unknown function (DUF1329) 84 450 1.5E-161 T 13-09-2016 IPR010752 Protein of unknown function DUF1329 THL1_RS18085 e03f354bc3a6bbca29d629b5862c5de3 414 Gene3D G3DSA:3.90.1150.10 264 395 8.1E-44 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS18085 e03f354bc3a6bbca29d629b5862c5de3 414 SUPERFAMILY SSF53383 9 394 2.99E-106 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS18085 e03f354bc3a6bbca29d629b5862c5de3 414 Gene3D G3DSA:3.40.640.10 50 263 4.5E-62 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS18085 e03f354bc3a6bbca29d629b5862c5de3 414 PANTHER PTHR11751:SF302 18 402 9.5E-268 T 13-09-2016 THL1_RS18085 e03f354bc3a6bbca29d629b5862c5de3 414 Pfam PF00155 Aminotransferase class I and II 37 387 3.3E-60 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS18085 e03f354bc3a6bbca29d629b5862c5de3 414 PANTHER PTHR11751 18 402 9.5E-268 T 13-09-2016 THL1_RS07895 532002d3ce9019c098cc0ec22239506b 347 PANTHER PTHR21499:SF2 1 340 9.4E-97 T 13-09-2016 THL1_RS07895 532002d3ce9019c098cc0ec22239506b 347 SUPERFAMILY SSF55347 160 325 4.64E-46 T 13-09-2016 THL1_RS07895 532002d3ce9019c098cc0ec22239506b 347 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 205 227 - T 13-09-2016 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 THL1_RS07895 532002d3ce9019c098cc0ec22239506b 347 Pfam PF00742 Homoserine dehydrogenase 160 338 6.3E-56 T 13-09-2016 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 THL1_RS07895 532002d3ce9019c098cc0ec22239506b 347 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 91 152 9.0E-5 T 13-09-2016 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 THL1_RS07895 532002d3ce9019c098cc0ec22239506b 347 Gene3D G3DSA:3.40.50.720 1 171 1.4E-41 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07895 532002d3ce9019c098cc0ec22239506b 347 PIRSF PIRSF036497 1 347 4.1E-106 T 13-09-2016 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 THL1_RS07895 532002d3ce9019c098cc0ec22239506b 347 SUPERFAMILY SSF51735 2 180 5.52E-20 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07895 532002d3ce9019c098cc0ec22239506b 347 PANTHER PTHR21499 1 340 9.4E-97 T 13-09-2016 THL1_RS07895 532002d3ce9019c098cc0ec22239506b 347 Gene3D G3DSA:3.30.360.10 172 321 5.5E-48 T 13-09-2016 THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 13-09-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 Gene3D G3DSA:1.20.200.10 89 355 3.0E-84 T 13-09-2016 THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 PRINTS PR00149 Fumarate lyase superfamily signature 131 149 7.6E-25 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 7.6E-25 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 PRINTS PR00149 Fumarate lyase superfamily signature 86 104 7.6E-25 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 7.6E-25 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 PANTHER PTHR11444:SF21 4 428 9.2E-202 T 13-09-2016 THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 427 3.8E-20 T 13-09-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 PANTHER PTHR11444 4 428 9.2E-202 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 1 334 4.7E-134 T 13-09-2016 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 SUPERFAMILY SSF48557 1 431 4.4E-118 T 13-09-2016 IPR008948 L-Aspartase-like GO:0003824 THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 PRINTS PR00145 Argininosuccinate lyase family signature 126 146 1.8E-11 T 13-09-2016 THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 PRINTS PR00145 Argininosuccinate lyase family signature 85 107 1.8E-11 T 13-09-2016 THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 1.8E-11 T 13-09-2016 THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 1.8E-11 T 13-09-2016 THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 SMART SM00998 349 428 1.9E-29 T 13-09-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 Pfam PF00206 Lyase 1 286 7.8E-64 T 13-09-2016 IPR022761 Fumarate lyase, N-terminal THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 Gene3D G3DSA:1.10.275.10 1 88 4.6E-31 T 13-09-2016 IPR024083 Fumarase/histidase, N-terminal THL1_RS12610 ef69e4bfd38ef463c70b9224ca548e77 436 Gene3D G3DSA:1.10.40.30 356 428 5.7E-31 T 13-09-2016 THL1_RS17400 c008874859884cdd93b0609b63d0dec6 307 Gene3D G3DSA:3.40.190.10 96 178 6.4E-25 T 13-09-2016 THL1_RS17400 c008874859884cdd93b0609b63d0dec6 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 4.8E-20 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS17400 c008874859884cdd93b0609b63d0dec6 307 SUPERFAMILY SSF53850 88 292 6.52E-32 T 13-09-2016 THL1_RS17400 c008874859884cdd93b0609b63d0dec6 307 Pfam PF03466 LysR substrate binding domain 90 289 2.8E-28 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS17400 c008874859884cdd93b0609b63d0dec6 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.4E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS17400 c008874859884cdd93b0609b63d0dec6 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.4E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS17400 c008874859884cdd93b0609b63d0dec6 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.4E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS17400 c008874859884cdd93b0609b63d0dec6 307 Gene3D G3DSA:3.40.190.10 179 259 2.0E-17 T 13-09-2016 THL1_RS17400 c008874859884cdd93b0609b63d0dec6 307 PANTHER PTHR30537 1 298 3.0E-90 T 13-09-2016 THL1_RS17400 c008874859884cdd93b0609b63d0dec6 307 PANTHER PTHR30537:SF26 1 298 3.0E-90 T 13-09-2016 THL1_RS17400 c008874859884cdd93b0609b63d0dec6 307 Gene3D G3DSA:1.10.10.10 2 86 1.2E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS17400 c008874859884cdd93b0609b63d0dec6 307 SUPERFAMILY SSF46785 4 86 2.94E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS28475 875f31a8a84a73a747b36535abc29a9d 630 Gene3D G3DSA:3.50.50.60 7 234 6.5E-53 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS28475 875f31a8a84a73a747b36535abc29a9d 630 PANTHER PTHR11806 2 625 0.0 T 13-09-2016 THL1_RS28475 875f31a8a84a73a747b36535abc29a9d 630 Pfam PF01134 Glucose inhibited division protein A 8 399 3.9E-169 T 13-09-2016 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 THL1_RS28475 875f31a8a84a73a747b36535abc29a9d 630 Pfam PF13932 GidA associated domain 402 614 1.0E-71 T 13-09-2016 IPR026904 GidA associated domain 3 THL1_RS28475 875f31a8a84a73a747b36535abc29a9d 630 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 622 42.586 T 13-09-2016 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 THL1_RS28475 875f31a8a84a73a747b36535abc29a9d 630 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 13-09-2016 IPR020595 MnmG-related, conserved site THL1_RS28475 875f31a8a84a73a747b36535abc29a9d 630 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 620 2.3E-276 T 13-09-2016 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 THL1_RS28475 875f31a8a84a73a747b36535abc29a9d 630 SMART SM01228 544 615 1.5E-41 T 13-09-2016 THL1_RS28475 875f31a8a84a73a747b36535abc29a9d 630 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 13-09-2016 IPR020595 MnmG-related, conserved site THL1_RS28475 875f31a8a84a73a747b36535abc29a9d 630 SUPERFAMILY SSF51905 97 261 1.2E-51 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS28475 875f31a8a84a73a747b36535abc29a9d 630 SUPERFAMILY SSF51905 7 66 1.2E-51 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS28475 875f31a8a84a73a747b36535abc29a9d 630 PANTHER PTHR11806:SF0 2 625 0.0 T 13-09-2016 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 SUPERFAMILY SSF47226 10 125 4.45E-20 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 Gene3D G3DSA:2.30.30.40 547 590 1.8E-14 T 13-09-2016 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 Gene3D G3DSA:2.30.30.40 460 481 1.8E-14 T 13-09-2016 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 SUPERFAMILY SSF52172 614 733 1.22E-33 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 317 459 8.3E-18 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 SUPERFAMILY SSF50341 459 590 1.27E-23 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 Pfam PF00072 Response regulator receiver domain 618 729 1.4E-23 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 Pfam PF01584 CheW-like domain 466 593 4.7E-17 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 Gene3D G3DSA:3.30.565.10 278 458 4.9E-33 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 Pfam PF01627 Hpt domain 12 103 1.1E-16 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 Gene3D G3DSA:3.40.50.2300 615 733 5.1E-34 T 13-09-2016 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 SMART SM00073 8 106 6.7E-13 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 PANTHER PTHR22617 2 25 2.4E-84 T 13-09-2016 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 SMART SM00387 312 460 1.9E-23 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 SUPERFAMILY SSF55874 277 458 4.98E-37 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 SMART SM00260 452 591 1.7E-12 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 PANTHER PTHR22617:SF6 2 25 2.4E-84 T 13-09-2016 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 PANTHER PTHR22617:SF6 252 607 2.4E-84 T 13-09-2016 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 7.5E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 7.5E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 376 7.5E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 SMART SM00448 615 729 5.0E-34 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 Gene3D G3DSA:2.40.50.180 484 546 1.2E-7 T 13-09-2016 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 PANTHER PTHR22617 252 607 2.4E-84 T 13-09-2016 THL1_RS02970 eda76434173ff29cc69950b1b5255cb2 733 Gene3D G3DSA:1.20.120.160 10 142 5.8E-24 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS22265 745bf7ad988832ce30f91004d7fde11c 216 PANTHER PTHR10520 4 197 3.4E-97 T 13-09-2016 THL1_RS22265 745bf7ad988832ce30f91004d7fde11c 216 Gene3D G3DSA:3.40.50.170 6 198 5.3E-73 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS22265 745bf7ad988832ce30f91004d7fde11c 216 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 6 191 32.224 T 13-09-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|UniPathway: UPA00074 THL1_RS22265 745bf7ad988832ce30f91004d7fde11c 216 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 137 160 - T 13-09-2016 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS22265 745bf7ad988832ce30f91004d7fde11c 216 SUPERFAMILY SSF53328 7 200 4.97E-66 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS22265 745bf7ad988832ce30f91004d7fde11c 216 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 7 194 8.4E-78 T 13-09-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|UniPathway: UPA00074 THL1_RS22265 745bf7ad988832ce30f91004d7fde11c 216 Pfam PF00551 Formyl transferase 7 184 3.5E-62 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS28075 4fcdd8828a3fc1a488a000cdf6b27bd3 384 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 55 281 1.5E-19 T 13-09-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THL1_RS28075 4fcdd8828a3fc1a488a000cdf6b27bd3 384 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 45 374 1.2E-52 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS28075 4fcdd8828a3fc1a488a000cdf6b27bd3 384 SUPERFAMILY SSF111369 47 264 3.27E-16 T 13-09-2016 THL1_RS28075 4fcdd8828a3fc1a488a000cdf6b27bd3 384 PANTHER PTHR32347 1 375 3.1E-45 T 13-09-2016 THL1_RS28075 4fcdd8828a3fc1a488a000cdf6b27bd3 384 Gene3D G3DSA:2.40.50.100 59 89 9.7E-12 T 13-09-2016 THL1_RS28075 4fcdd8828a3fc1a488a000cdf6b27bd3 384 Gene3D G3DSA:2.40.50.100 178 204 9.7E-12 T 13-09-2016 THL1_RS28075 4fcdd8828a3fc1a488a000cdf6b27bd3 384 PANTHER PTHR32347:SF16 1 375 3.1E-45 T 13-09-2016 THL1_RS18705 75580cca2decdc26323d061786884d53 146 Pfam PF04134 Protein of unknown function, DUF393 17 126 3.9E-32 T 13-09-2016 IPR007263 Protein of unknown function DUF393 THL1_RS18705 75580cca2decdc26323d061786884d53 146 PANTHER PTHR33639 8 142 2.4E-50 T 13-09-2016 THL1_RS18705 75580cca2decdc26323d061786884d53 146 PANTHER PTHR33639:SF3 8 142 2.4E-50 T 13-09-2016 THL1_RS07495 4c999db267c3f27926ca8491ade3cb79 284 Gene3D G3DSA:3.40.50.170 88 279 8.5E-53 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS07495 4c999db267c3f27926ca8491ade3cb79 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 89 111 1.4E-48 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS07495 4c999db267c3f27926ca8491ade3cb79 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 111 138 1.4E-48 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS07495 4c999db267c3f27926ca8491ade3cb79 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 6 32 1.4E-48 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS07495 4c999db267c3f27926ca8491ade3cb79 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 235 257 1.4E-48 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS07495 4c999db267c3f27926ca8491ade3cb79 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 38 50 1.4E-48 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS07495 4c999db267c3f27926ca8491ade3cb79 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 257 282 1.4E-48 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS07495 4c999db267c3f27926ca8491ade3cb79 284 PIRSF PIRSF036480 1 284 1.6E-106 T 13-09-2016 THL1_RS07495 4c999db267c3f27926ca8491ade3cb79 284 PANTHER PTHR10520:SF7 1 277 1.1E-139 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS07495 4c999db267c3f27926ca8491ade3cb79 284 Pfam PF00551 Formyl transferase 88 265 2.8E-34 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS07495 4c999db267c3f27926ca8491ade3cb79 284 PANTHER PTHR10520 1 277 1.1E-139 T 13-09-2016 THL1_RS07495 4c999db267c3f27926ca8491ade3cb79 284 SUPERFAMILY SSF53328 88 283 2.09E-59 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS07495 4c999db267c3f27926ca8491ade3cb79 284 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 5 283 5.5E-98 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS07495 4c999db267c3f27926ca8491ade3cb79 284 Gene3D G3DSA:3.30.70.260 1 82 2.8E-18 T 13-09-2016 THL1_RS07495 4c999db267c3f27926ca8491ade3cb79 284 SUPERFAMILY SSF55021 2 81 6.62E-12 T 13-09-2016 THL1_RS07495 4c999db267c3f27926ca8491ade3cb79 284 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 1 283 46.109 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS28355 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055 75 184 6.7E-22 T 13-09-2016 THL1_RS28355 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055:SF3 200 371 6.7E-22 T 13-09-2016 THL1_RS28355 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055:SF3 75 184 6.7E-22 T 13-09-2016 THL1_RS28355 d82c5555ab0c94a5a98cc060ee2c742b 381 Pfam PF01548 Transposase 70 180 3.6E-9 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS28355 d82c5555ab0c94a5a98cc060ee2c742b 381 Pfam PF02371 Transposase IS116/IS110/IS902 family 250 329 2.0E-15 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS28355 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055 200 371 6.7E-22 T 13-09-2016 THL1_RS07265 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055 75 184 6.7E-22 T 13-09-2016 THL1_RS07265 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055:SF3 200 371 6.7E-22 T 13-09-2016 THL1_RS07265 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055:SF3 75 184 6.7E-22 T 13-09-2016 THL1_RS07265 d82c5555ab0c94a5a98cc060ee2c742b 381 Pfam PF01548 Transposase 70 180 3.6E-9 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS07265 d82c5555ab0c94a5a98cc060ee2c742b 381 Pfam PF02371 Transposase IS116/IS110/IS902 family 250 329 2.0E-15 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS07265 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055 200 371 6.7E-22 T 13-09-2016 THL1_RS22860 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055 75 184 6.7E-22 T 13-09-2016 THL1_RS22860 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055:SF3 200 371 6.7E-22 T 13-09-2016 THL1_RS22860 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055:SF3 75 184 6.7E-22 T 13-09-2016 THL1_RS22860 d82c5555ab0c94a5a98cc060ee2c742b 381 Pfam PF01548 Transposase 70 180 3.6E-9 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS22860 d82c5555ab0c94a5a98cc060ee2c742b 381 Pfam PF02371 Transposase IS116/IS110/IS902 family 250 329 2.0E-15 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS22860 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055 200 371 6.7E-22 T 13-09-2016 THL1_RS07740 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055 75 184 6.7E-22 T 13-09-2016 THL1_RS07740 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055:SF3 200 371 6.7E-22 T 13-09-2016 THL1_RS07740 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055:SF3 75 184 6.7E-22 T 13-09-2016 THL1_RS07740 d82c5555ab0c94a5a98cc060ee2c742b 381 Pfam PF01548 Transposase 70 180 3.6E-9 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS07740 d82c5555ab0c94a5a98cc060ee2c742b 381 Pfam PF02371 Transposase IS116/IS110/IS902 family 250 329 2.0E-15 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS07740 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055 200 371 6.7E-22 T 13-09-2016 THL1_RS26550 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055 75 184 6.7E-22 T 13-09-2016 THL1_RS26550 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055:SF3 200 371 6.7E-22 T 13-09-2016 THL1_RS26550 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055:SF3 75 184 6.7E-22 T 13-09-2016 THL1_RS26550 d82c5555ab0c94a5a98cc060ee2c742b 381 Pfam PF01548 Transposase 70 180 3.6E-9 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS26550 d82c5555ab0c94a5a98cc060ee2c742b 381 Pfam PF02371 Transposase IS116/IS110/IS902 family 250 329 2.0E-15 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS26550 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055 200 371 6.7E-22 T 13-09-2016 THL1_RS20280 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055 75 184 6.7E-22 T 13-09-2016 THL1_RS20280 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055:SF3 200 371 6.7E-22 T 13-09-2016 THL1_RS20280 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055:SF3 75 184 6.7E-22 T 13-09-2016 THL1_RS20280 d82c5555ab0c94a5a98cc060ee2c742b 381 Pfam PF01548 Transposase 70 180 3.6E-9 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS20280 d82c5555ab0c94a5a98cc060ee2c742b 381 Pfam PF02371 Transposase IS116/IS110/IS902 family 250 329 2.0E-15 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS20280 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055 200 371 6.7E-22 T 13-09-2016 THL1_RS03825 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055 75 184 6.7E-22 T 13-09-2016 THL1_RS03825 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055:SF3 200 371 6.7E-22 T 13-09-2016 THL1_RS03825 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055:SF3 75 184 6.7E-22 T 13-09-2016 THL1_RS03825 d82c5555ab0c94a5a98cc060ee2c742b 381 Pfam PF01548 Transposase 70 180 3.6E-9 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS03825 d82c5555ab0c94a5a98cc060ee2c742b 381 Pfam PF02371 Transposase IS116/IS110/IS902 family 250 329 2.0E-15 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS03825 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055 200 371 6.7E-22 T 13-09-2016 THL1_RS25760 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055 75 184 6.7E-22 T 13-09-2016 THL1_RS25760 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055:SF3 200 371 6.7E-22 T 13-09-2016 THL1_RS25760 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055:SF3 75 184 6.7E-22 T 13-09-2016 THL1_RS25760 d82c5555ab0c94a5a98cc060ee2c742b 381 Pfam PF01548 Transposase 70 180 3.6E-9 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS25760 d82c5555ab0c94a5a98cc060ee2c742b 381 Pfam PF02371 Transposase IS116/IS110/IS902 family 250 329 2.0E-15 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS25760 d82c5555ab0c94a5a98cc060ee2c742b 381 PANTHER PTHR33055 200 371 6.7E-22 T 13-09-2016 THL1_RS23100 febe402d45b49e0ee2885db9243a0de1 274 SUPERFAMILY SSF56176 190 268 9.82E-19 T 13-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THL1_RS23100 febe402d45b49e0ee2885db9243a0de1 274 SMART SM01091 191 269 6.6E-20 T 13-09-2016 IPR005170 Transporter-associated domain THL1_RS23100 febe402d45b49e0ee2885db9243a0de1 274 Pfam PF03471 Transporter associated domain 192 264 2.7E-15 T 13-09-2016 IPR005170 Transporter-associated domain THL1_RS23100 febe402d45b49e0ee2885db9243a0de1 274 PANTHER PTHR22777 49 273 5.6E-66 T 13-09-2016 THL1_RS23100 febe402d45b49e0ee2885db9243a0de1 274 SUPERFAMILY SSF54631 50 184 5.43E-23 T 13-09-2016 THL1_RS23100 febe402d45b49e0ee2885db9243a0de1 274 Gene3D G3DSA:3.30.465.10 167 266 7.3E-22 T 13-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THL1_RS23100 febe402d45b49e0ee2885db9243a0de1 274 Gene3D G3DSA:3.10.580.10 48 166 3.7E-14 T 13-09-2016 THL1_RS23100 febe402d45b49e0ee2885db9243a0de1 274 Pfam PF00571 CBS domain 125 175 2.7E-5 T 13-09-2016 IPR000644 CBS domain THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 Gene3D G3DSA:3.40.50.300 591 784 4.2E-57 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 SUPERFAMILY SSF52540 522 781 8.69E-62 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 Gene3D G3DSA:3.30.2060.10 130 204 2.2E-14 T 13-09-2016 THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 SUPERFAMILY SSF52540 780 988 1.92E-48 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 SUPERFAMILY SSF52540 351 465 4.25E-31 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 Pfam PF03461 TRCF domain 1007 1097 2.8E-26 T 13-09-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 146 1079 0.0 T 13-09-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 SMART SM00490 824 908 5.3E-17 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 SMART SM01058 477 574 3.7E-49 T 13-09-2016 IPR003711 CarD-like/TRCF domain THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 Gene3D G3DSA:3.40.50.300 793 954 6.3E-36 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 SUPERFAMILY SSF141259 469 546 3.01E-22 T 13-09-2016 IPR003711 CarD-like/TRCF domain THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 PANTHER PTHR14025:SF21 382 1143 0.0 T 13-09-2016 THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 Pfam PF00271 Helicase conserved C-terminal domain 803 907 1.2E-17 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 25 1139 28.964 T 13-09-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 PANTHER PTHR14025 382 1143 0.0 T 13-09-2016 THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 SMART SM00487 598 788 1.0E-33 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 Pfam PF00270 DEAD/DEAH box helicase 603 763 2.3E-18 T 13-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 SMART SM00982 1006 1106 4.8E-50 T 13-09-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 SUPERFAMILY SSF52540 11 340 1.95E-104 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 Pfam PF02559 CarD-like/TRCF domain 478 573 7.6E-23 T 13-09-2016 IPR003711 CarD-like/TRCF domain THL1_RS10675 a31ffbc542d95c25c66c261402ae78d2 1146 SUPERFAMILY SSF143517 992 1144 1.15E-42 T 13-09-2016 THL1_RS18835 6bc56d00d62411deb8f80b45b7d415f6 203 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 4 181 5.7E-84 T 13-09-2016 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO THL1_RS18835 6bc56d00d62411deb8f80b45b7d415f6 203 PANTHER PTHR10422:SF23 23 160 1.9E-91 T 13-09-2016 THL1_RS18835 6bc56d00d62411deb8f80b45b7d415f6 203 SUPERFAMILY SSF46626 16 196 1.14E-30 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18835 6bc56d00d62411deb8f80b45b7d415f6 203 Gene3D G3DSA:1.10.760.10 16 196 9.7E-39 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18835 6bc56d00d62411deb8f80b45b7d415f6 203 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 4 180 9.7E-87 T 13-09-2016 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO THL1_RS18835 6bc56d00d62411deb8f80b45b7d415f6 203 PANTHER PTHR10422 23 160 1.9E-91 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS09010 a43bdca6cb0bf4e1c19f55c8a7fa0c4f 98 PANTHER PTHR33713:SF2 1 86 4.1E-26 T 13-09-2016 THL1_RS09010 a43bdca6cb0bf4e1c19f55c8a7fa0c4f 98 PANTHER PTHR33713 1 86 4.1E-26 T 13-09-2016 THL1_RS09010 a43bdca6cb0bf4e1c19f55c8a7fa0c4f 98 SUPERFAMILY SSF143120 1 69 9.68E-10 T 13-09-2016 THL1_RS26275 b63fd21a73074326012ee97922c4100e 472 Gene3D G3DSA:3.40.50.720 153 239 9.3E-34 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS26275 b63fd21a73074326012ee97922c4100e 472 Gene3D G3DSA:3.40.50.720 401 470 9.3E-34 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS26275 b63fd21a73074326012ee97922c4100e 472 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 150 459 1.2E-24 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS26275 b63fd21a73074326012ee97922c4100e 472 PANTHER PTHR11938 28 470 2.4E-287 T 13-09-2016 THL1_RS26275 b63fd21a73074326012ee97922c4100e 472 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 27 137 3.0E-38 T 13-09-2016 IPR028261 Dihydroprymidine dehydrogenase domain II THL1_RS26275 b63fd21a73074326012ee97922c4100e 472 TIGRFAM TIGR01318 gltD_gamma_fam: glutamate synthase, small subunit 9 472 1.5E-237 T 13-09-2016 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 GO:0006537|GO:0016639 THL1_RS26275 b63fd21a73074326012ee97922c4100e 472 Gene3D G3DSA:3.50.50.60 240 400 5.2E-49 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS26275 b63fd21a73074326012ee97922c4100e 472 PRINTS PR00419 Adrenodoxin reductase family signature 174 187 1.1E-34 T 13-09-2016 THL1_RS26275 b63fd21a73074326012ee97922c4100e 472 PRINTS PR00419 Adrenodoxin reductase family signature 326 339 1.1E-34 T 13-09-2016 THL1_RS26275 b63fd21a73074326012ee97922c4100e 472 PRINTS PR00419 Adrenodoxin reductase family signature 151 173 1.1E-34 T 13-09-2016 THL1_RS26275 b63fd21a73074326012ee97922c4100e 472 PRINTS PR00419 Adrenodoxin reductase family signature 292 306 1.1E-34 T 13-09-2016 THL1_RS26275 b63fd21a73074326012ee97922c4100e 472 PRINTS PR00419 Adrenodoxin reductase family signature 216 226 1.1E-34 T 13-09-2016 THL1_RS26275 b63fd21a73074326012ee97922c4100e 472 SUPERFAMILY SSF46548 11 160 4.5E-39 T 13-09-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 THL1_RS26275 b63fd21a73074326012ee97922c4100e 472 PANTHER PTHR11938:SF93 28 470 2.4E-287 T 13-09-2016 THL1_RS26275 b63fd21a73074326012ee97922c4100e 472 Gene3D G3DSA:1.10.1060.10 10 152 2.1E-44 T 13-09-2016 THL1_RS26275 b63fd21a73074326012ee97922c4100e 472 SUPERFAMILY SSF51971 148 401 1.35E-69 T 13-09-2016 THL1_RS26420 ad3d864dad0f3a30479dea6a4f468a85 256 PANTHER PTHR10108:SF864 9 255 1.7E-174 T 13-09-2016 THL1_RS26420 ad3d864dad0f3a30479dea6a4f468a85 256 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 163 177 - T 13-09-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 THL1_RS26420 ad3d864dad0f3a30479dea6a4f468a85 256 PANTHER PTHR10108 9 255 1.7E-174 T 13-09-2016 THL1_RS26420 ad3d864dad0f3a30479dea6a4f468a85 256 SUPERFAMILY SSF53335 19 253 1.7E-53 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS26420 ad3d864dad0f3a30479dea6a4f468a85 256 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 41 56 - T 13-09-2016 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 THL1_RS26420 ad3d864dad0f3a30479dea6a4f468a85 256 Pfam PF01209 ubiE/COQ5 methyltransferase family 25 255 3.2E-98 T 13-09-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 THL1_RS26420 ad3d864dad0f3a30479dea6a4f468a85 256 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 21 255 39.242 T 13-09-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 THL1_RS26420 ad3d864dad0f3a30479dea6a4f468a85 256 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 30 255 1.2E-84 T 13-09-2016 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|UniPathway: UPA00079 THL1_RS26420 ad3d864dad0f3a30479dea6a4f468a85 256 Gene3D G3DSA:3.40.50.150 28 252 1.6E-59 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS12085 30f11454a6cfb9be13e550f7393e0afa 219 Gene3D G3DSA:1.10.10.10 7 96 8.2E-35 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12085 30f11454a6cfb9be13e550f7393e0afa 219 Pfam PF04337 Protein of unknown function, DUF480 14 158 2.8E-53 T 13-09-2016 IPR007432 Protein of unknown function DUF480 THL1_RS12085 30f11454a6cfb9be13e550f7393e0afa 219 SUPERFAMILY SSF46785 94 173 3.62E-26 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12085 30f11454a6cfb9be13e550f7393e0afa 219 PANTHER PTHR38768 2 219 6.2E-79 T 13-09-2016 THL1_RS12085 30f11454a6cfb9be13e550f7393e0afa 219 SUPERFAMILY SSF46785 13 91 5.44E-28 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12085 30f11454a6cfb9be13e550f7393e0afa 219 Gene3D G3DSA:1.10.10.10 99 174 2.5E-30 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12085 30f11454a6cfb9be13e550f7393e0afa 219 PANTHER PTHR38768:SF1 2 219 6.2E-79 T 13-09-2016 THL1_RS12085 30f11454a6cfb9be13e550f7393e0afa 219 Hamap MF_01584 UPF0502 protein YceH [yceH]. 14 216 28.743 T 13-09-2016 IPR007432 Protein of unknown function DUF480 THL1_RS04815 e6aae3471cbced089a8fd9ee29049e06 322 Pfam PF00348 Polyprenyl synthetase 31 272 2.3E-70 T 13-09-2016 IPR000092 Polyprenyl synthetase GO:0008299 THL1_RS04815 e6aae3471cbced089a8fd9ee29049e06 322 PANTHER PTHR12001 6 322 2.2E-117 T 13-09-2016 IPR017446 Polyprenyl synthetase-related THL1_RS04815 e6aae3471cbced089a8fd9ee29049e06 322 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 13-09-2016 IPR000092 Polyprenyl synthetase GO:0008299 THL1_RS04815 e6aae3471cbced089a8fd9ee29049e06 322 Gene3D G3DSA:1.10.600.10 4 321 6.5E-100 T 13-09-2016 IPR008949 Isoprenoid synthase domain THL1_RS04815 e6aae3471cbced089a8fd9ee29049e06 322 PANTHER PTHR12001:SF47 6 322 2.2E-117 T 13-09-2016 THL1_RS04815 e6aae3471cbced089a8fd9ee29049e06 322 SUPERFAMILY SSF48576 5 321 1.87E-99 T 13-09-2016 IPR008949 Isoprenoid synthase domain THL1_RS04815 e6aae3471cbced089a8fd9ee29049e06 322 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 13-09-2016 IPR000092 Polyprenyl synthetase GO:0008299 THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 SUPERFAMILY SSF52540 338 611 3.43E-47 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 Gene3D G3DSA:1.10.8.60 520 610 3.1E-27 T 13-09-2016 THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 PANTHER PTHR10046 5 799 0.0 T 13-09-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 SUPERFAMILY SSF88697 35 228 8.95E-19 T 13-09-2016 IPR015947 PUA-like domain THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 597 797 1.8E-75 T 13-09-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 SUPERFAMILY SSF54211 621 798 2.01E-45 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 Gene3D G3DSA:3.30.230.10 621 798 2.3E-62 T 13-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 PIRSF PIRSF001174 14 799 9.9E-267 T 13-09-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 Gene3D G3DSA:3.40.50.300 338 517 2.2E-33 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 33 228 2.8E-25 T 13-09-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 Hamap MF_01973 Lon protease [lon]. 33 799 58.219 T 13-09-2016 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 380 517 7.0E-22 T 13-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 703 711 - T 13-09-2016 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 TIGRFAM TIGR00763 lon: endopeptidase La 35 798 8.0E-270 T 13-09-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 384 403 2.7E-47 T 13-09-2016 THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 700 719 2.7E-47 T 13-09-2016 THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 753 771 2.7E-47 T 13-09-2016 THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 730 749 2.7E-47 T 13-09-2016 THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 621 637 2.7E-47 T 13-09-2016 THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 SMART SM00382 376 521 1.7E-11 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS21250 a39a04a97b253b984598749c222a70d7 799 SMART SM00464 32 229 8.6E-18 T 13-09-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 THL1_RS17485 92922472c6babb637837748ccdfaa748 252 Gene3D G3DSA:3.40.50.300 3 246 9.9E-63 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17485 92922472c6babb637837748ccdfaa748 252 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 246 2.0E-8 T 13-09-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal THL1_RS17485 92922472c6babb637837748ccdfaa748 252 Pfam PF00005 ABC transporter 22 177 4.0E-25 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS17485 92922472c6babb637837748ccdfaa748 252 PANTHER PTHR24220 7 246 2.8E-112 T 13-09-2016 THL1_RS17485 92922472c6babb637837748ccdfaa748 252 PANTHER PTHR24220:SF400 7 246 2.8E-112 T 13-09-2016 THL1_RS17485 92922472c6babb637837748ccdfaa748 252 SUPERFAMILY SSF52540 4 246 9.59E-58 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17485 92922472c6babb637837748ccdfaa748 252 SMART SM00382 30 232 7.1E-5 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS01000 6cac9162e380021bc4148b84e93b3f37 294 PANTHER PTHR30222 1 275 1.1E-82 T 13-09-2016 THL1_RS01000 6cac9162e380021bc4148b84e93b3f37 294 PANTHER PTHR30222:SF1 1 275 1.1E-82 T 13-09-2016 THL1_RS01000 6cac9162e380021bc4148b84e93b3f37 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 260 1.1E-14 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01000 6cac9162e380021bc4148b84e93b3f37 294 SUPERFAMILY SSF161098 3 261 2.34E-50 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01000 6cac9162e380021bc4148b84e93b3f37 294 Gene3D G3DSA:1.10.3720.10 2 266 1.7E-55 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS22130 495ad69a35f50f14148ae03703648173 174 SUPERFAMILY SSF53098 3 156 5.31E-52 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS22130 495ad69a35f50f14148ae03703648173 174 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 2 153 46.589 T 13-09-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THL1_RS22130 495ad69a35f50f14148ae03703648173 174 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 4 155 5.3E-60 T 13-09-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THL1_RS22130 495ad69a35f50f14148ae03703648173 174 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 147 - T 13-09-2016 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 THL1_RS22130 495ad69a35f50f14148ae03703648173 174 Gene3D G3DSA:3.30.420.10 3 156 1.0E-61 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS22130 495ad69a35f50f14148ae03703648173 174 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 4 150 9.4E-64 T 13-09-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THL1_RS22130 495ad69a35f50f14148ae03703648173 174 PANTHER PTHR30194 1 169 1.8E-67 T 13-09-2016 THL1_RS22130 495ad69a35f50f14148ae03703648173 174 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 3.5E-39 T 13-09-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THL1_RS22130 495ad69a35f50f14148ae03703648173 174 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 138 150 3.5E-39 T 13-09-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THL1_RS22130 495ad69a35f50f14148ae03703648173 174 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 5 18 3.5E-39 T 13-09-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THL1_RS22130 495ad69a35f50f14148ae03703648173 174 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 3.5E-39 T 13-09-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THL1_RS22130 495ad69a35f50f14148ae03703648173 174 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 3.5E-39 T 13-09-2016 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THL1_RS25675 2b86cc11c1d3335b86b60357814cd804 238 PANTHER PTHR24220 7 236 1.1E-157 T 13-09-2016 THL1_RS25675 2b86cc11c1d3335b86b60357814cd804 238 SMART SM00382 30 222 1.6E-5 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS25675 2b86cc11c1d3335b86b60357814cd804 238 SUPERFAMILY SSF52540 4 235 5.01E-61 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25675 2b86cc11c1d3335b86b60357814cd804 238 PANTHER PTHR24220:SF515 7 236 1.1E-157 T 13-09-2016 THL1_RS25675 2b86cc11c1d3335b86b60357814cd804 238 Pfam PF00005 ABC transporter 21 165 3.4E-31 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS25675 2b86cc11c1d3335b86b60357814cd804 238 Gene3D G3DSA:3.40.50.300 2 233 1.3E-60 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25675 2b86cc11c1d3335b86b60357814cd804 238 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS25665 c032270b11986cf38780c6bdfd4d0615 107 SUPERFAMILY SSF54909 1 98 8.58E-25 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS25665 c032270b11986cf38780c6bdfd4d0615 107 Gene3D G3DSA:3.30.70.900 1 92 2.5E-34 T 13-09-2016 THL1_RS02310 1915a6e3e9d54a0ee1cd8af0250689c2 265 Pfam PF00892 EamA-like transporter family 131 261 7.5E-12 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS02310 1915a6e3e9d54a0ee1cd8af0250689c2 265 PANTHER PTHR22911:SF61 1 263 8.1E-58 T 13-09-2016 THL1_RS02310 1915a6e3e9d54a0ee1cd8af0250689c2 265 PANTHER PTHR22911 1 263 8.1E-58 T 13-09-2016 THL1_RS02310 1915a6e3e9d54a0ee1cd8af0250689c2 265 SUPERFAMILY SSF103481 172 263 2.88E-13 T 13-09-2016 THL1_RS02310 1915a6e3e9d54a0ee1cd8af0250689c2 265 SUPERFAMILY SSF103481 26 117 2.35E-12 T 13-09-2016 THL1_RS03975 978b3f79fd75351dde2cdf44d16933b9 368 PANTHER PTHR33619 62 354 8.6E-46 T 13-09-2016 THL1_RS03975 978b3f79fd75351dde2cdf44d16933b9 368 Gene3D G3DSA:3.30.1950.10 79 153 2.5E-27 T 13-09-2016 THL1_RS03975 978b3f79fd75351dde2cdf44d16933b9 368 Pfam PF02563 Polysaccharide biosynthesis/export protein 72 155 1.1E-25 T 13-09-2016 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 THL1_RS03975 978b3f79fd75351dde2cdf44d16933b9 368 PANTHER PTHR33619:SF3 62 354 8.6E-46 T 13-09-2016 THL1_RS03975 978b3f79fd75351dde2cdf44d16933b9 368 Gene3D G3DSA:1.20.5.70 336 349 2.1E-4 T 13-09-2016 THL1_RS03975 978b3f79fd75351dde2cdf44d16933b9 368 Gene3D G3DSA:3.10.560.10 234 332 4.0E-26 T 13-09-2016 THL1_RS03975 978b3f79fd75351dde2cdf44d16933b9 368 Gene3D G3DSA:3.10.560.10 154 233 5.0E-14 T 13-09-2016 THL1_RS24570 7928f8040b1cb07c19c44fb3a88b84cb 209 Pfam PF01810 LysE type translocator 15 202 1.1E-34 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS24570 7928f8040b1cb07c19c44fb3a88b84cb 209 PIRSF PIRSF006324 1 205 1.2E-49 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS24570 7928f8040b1cb07c19c44fb3a88b84cb 209 PANTHER PTHR30086 1 209 2.8E-47 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS20980 8873ac912589ee1ce9e6afc4efc5de91 565 PANTHER PTHR32089 205 565 3.6E-94 T 13-09-2016 THL1_RS20980 8873ac912589ee1ce9e6afc4efc5de91 565 SUPERFAMILY SSF58104 256 565 9.94E-65 T 13-09-2016 THL1_RS20980 8873ac912589ee1ce9e6afc4efc5de91 565 SMART SM00304 235 288 7.7E-7 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS20980 8873ac912589ee1ce9e6afc4efc5de91 565 Gene3D G3DSA:1.10.287.950 317 535 1.0E-52 T 13-09-2016 THL1_RS20980 8873ac912589ee1ce9e6afc4efc5de91 565 SMART SM00283 303 564 2.5E-72 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS20980 8873ac912589ee1ce9e6afc4efc5de91 565 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 358 563 1.1E-43 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS20980 8873ac912589ee1ce9e6afc4efc5de91 565 Pfam PF00672 HAMP domain 218 285 7.2E-11 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS20980 8873ac912589ee1ce9e6afc4efc5de91 565 Pfam PF02203 Tar ligand binding domain homologue 2 143 9.4E-13 T 13-09-2016 IPR003122 Chemotaxis methyl-accepting receptor, ligand-binding GO:0004888|GO:0006935|GO:0007165|GO:0016020 THL1_RS23580 338d6e12a85a6017bfb3c7bb52607813 148 PANTHER PTHR19384:SF81 2 147 8.5E-17 T 13-09-2016 THL1_RS23580 338d6e12a85a6017bfb3c7bb52607813 148 PANTHER PTHR19384 2 147 8.5E-17 T 13-09-2016 THL1_RS23580 338d6e12a85a6017bfb3c7bb52607813 148 Gene3D G3DSA:3.40.50.360 2 147 3.8E-28 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS23580 338d6e12a85a6017bfb3c7bb52607813 148 Pfam PF00258 Flavodoxin 5 139 9.7E-16 T 13-09-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 THL1_RS23580 338d6e12a85a6017bfb3c7bb52607813 148 SUPERFAMILY SSF52218 2 147 2.67E-31 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS27870 8e43ba2af2a3193fc989cbced1c1b9c5 239 PANTHER PTHR11953 1 237 8.9E-89 T 13-09-2016 THL1_RS27870 8e43ba2af2a3193fc989cbced1c1b9c5 239 Pfam PF03725 3' exoribonuclease family, domain 2 159 225 2.2E-10 T 13-09-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 THL1_RS27870 8e43ba2af2a3193fc989cbced1c1b9c5 239 Hamap MF_00564 Ribonuclease PH [rph]. 2 238 49.857 T 13-09-2016 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 THL1_RS27870 8e43ba2af2a3193fc989cbced1c1b9c5 239 SUPERFAMILY SSF55666 153 238 8.12E-25 T 13-09-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 THL1_RS27870 8e43ba2af2a3193fc989cbced1c1b9c5 239 SUPERFAMILY SSF54211 2 182 1.57E-46 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS27870 8e43ba2af2a3193fc989cbced1c1b9c5 239 ProSitePatterns PS01277 Ribonuclease PH signature. 117 129 - T 13-09-2016 IPR018336 Ribonuclease PH, conserved site THL1_RS27870 8e43ba2af2a3193fc989cbced1c1b9c5 239 Pfam PF01138 3' exoribonuclease family, domain 1 11 141 3.4E-26 T 13-09-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 THL1_RS27870 8e43ba2af2a3193fc989cbced1c1b9c5 239 PANTHER PTHR11953:SF0 1 237 8.9E-89 T 13-09-2016 THL1_RS27870 8e43ba2af2a3193fc989cbced1c1b9c5 239 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 237 2.5E-116 T 13-09-2016 IPR002381 Ribonuclease phosphorolytic, bacterial-type GO:0000049|GO:0004549|GO:0008033 THL1_RS27870 8e43ba2af2a3193fc989cbced1c1b9c5 239 Gene3D G3DSA:3.30.230.70 7 237 1.1E-36 T 13-09-2016 IPR027408 PNPase/RNase PH domain THL1_RS07405 8bf0accd79ef9b52cdb61544668ca5f1 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 282 4.5E-20 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07405 8bf0accd79ef9b52cdb61544668ca5f1 292 SUPERFAMILY SSF161098 71 270 1.31E-43 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07405 8bf0accd79ef9b52cdb61544668ca5f1 292 PANTHER PTHR30450 54 291 4.1E-129 T 13-09-2016 THL1_RS07405 8bf0accd79ef9b52cdb61544668ca5f1 292 PANTHER PTHR30450:SF2 54 291 4.1E-129 T 13-09-2016 THL1_RS07405 8bf0accd79ef9b52cdb61544668ca5f1 292 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 71 179 3.0E-19 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS07405 8bf0accd79ef9b52cdb61544668ca5f1 292 Gene3D G3DSA:1.10.3720.10 69 285 5.9E-47 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS20420 24d91f99a90e518736d4943daeeb8c9c 201 SUPERFAMILY SSF46689 11 83 3.34E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS20420 24d91f99a90e518736d4943daeeb8c9c 201 Gene3D G3DSA:1.10.357.10 10 196 5.7E-26 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS20420 24d91f99a90e518736d4943daeeb8c9c 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 61 2.2E-8 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20420 24d91f99a90e518736d4943daeeb8c9c 201 PANTHER PTHR30055 6 167 1.9E-17 T 13-09-2016 THL1_RS09745 a861ed5e79dd22099ff6a9335f79e3c6 293 PANTHER PTHR22911:SF70 10 293 2.4E-102 T 13-09-2016 THL1_RS09745 a861ed5e79dd22099ff6a9335f79e3c6 293 SUPERFAMILY SSF103481 51 152 2.48E-15 T 13-09-2016 THL1_RS09745 a861ed5e79dd22099ff6a9335f79e3c6 293 PANTHER PTHR22911 10 293 2.4E-102 T 13-09-2016 THL1_RS09745 a861ed5e79dd22099ff6a9335f79e3c6 293 SUPERFAMILY SSF103481 197 291 1.31E-10 T 13-09-2016 THL1_RS09745 a861ed5e79dd22099ff6a9335f79e3c6 293 Pfam PF00892 EamA-like transporter family 16 148 1.6E-17 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS09745 a861ed5e79dd22099ff6a9335f79e3c6 293 Pfam PF00892 EamA-like transporter family 158 286 1.0E-7 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS20460 b28abbb1c83a4c3b3b2dce3d82bf3e08 383 Gene3D G3DSA:1.10.540.10 3 119 2.5E-41 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS20460 b28abbb1c83a4c3b3b2dce3d82bf3e08 383 PANTHER PTHR10909 3 378 2.8E-165 T 13-09-2016 THL1_RS20460 b28abbb1c83a4c3b3b2dce3d82bf3e08 383 SUPERFAMILY SSF56645 2 243 1.23E-82 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS20460 b28abbb1c83a4c3b3b2dce3d82bf3e08 383 Gene3D G3DSA:1.20.140.10 222 380 9.4E-71 T 13-09-2016 THL1_RS20460 b28abbb1c83a4c3b3b2dce3d82bf3e08 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS20460 b28abbb1c83a4c3b3b2dce3d82bf3e08 383 Gene3D G3DSA:2.40.110.10 122 221 4.2E-40 T 13-09-2016 THL1_RS20460 b28abbb1c83a4c3b3b2dce3d82bf3e08 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 1.2E-27 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS20460 b28abbb1c83a4c3b3b2dce3d82bf3e08 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 2.6E-38 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS20460 b28abbb1c83a4c3b3b2dce3d82bf3e08 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 1.2E-49 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS20460 b28abbb1c83a4c3b3b2dce3d82bf3e08 383 SUPERFAMILY SSF47203 229 381 2.74E-58 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS20460 b28abbb1c83a4c3b3b2dce3d82bf3e08 383 PANTHER PTHR10909:SF10 3 378 2.8E-165 T 13-09-2016 THL1_RS05645 562bdd7881d3ea828f27cfef2f3a3fd1 486 Gene3D G3DSA:3.90.190.20 323 469 4.6E-53 T 13-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 THL1_RS05645 562bdd7881d3ea828f27cfef2f3a3fd1 486 SUPERFAMILY SSF53623 102 319 5.1E-75 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05645 562bdd7881d3ea828f27cfef2f3a3fd1 486 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 16 473 44.067 T 13-09-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS05645 562bdd7881d3ea828f27cfef2f3a3fd1 486 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 18 467 3.0E-170 T 13-09-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS05645 562bdd7881d3ea828f27cfef2f3a3fd1 486 SUPERFAMILY SSF53244 320 468 2.01E-46 T 13-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 THL1_RS05645 562bdd7881d3ea828f27cfef2f3a3fd1 486 Pfam PF08245 Mur ligase middle domain 121 301 4.4E-28 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05645 562bdd7881d3ea828f27cfef2f3a3fd1 486 Gene3D G3DSA:3.40.1190.10 105 322 3.1E-84 T 13-09-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05645 562bdd7881d3ea828f27cfef2f3a3fd1 486 Gene3D G3DSA:3.40.50.720 17 103 1.2E-35 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS05645 562bdd7881d3ea828f27cfef2f3a3fd1 486 Pfam PF02875 Mur ligase family, glutamate ligase domain 321 411 1.1E-20 T 13-09-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 THL1_RS05645 562bdd7881d3ea828f27cfef2f3a3fd1 486 Pfam PF01225 Mur ligase family, catalytic domain 18 116 1.7E-26 T 13-09-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 THL1_RS05645 562bdd7881d3ea828f27cfef2f3a3fd1 486 PANTHER PTHR23135 11 462 3.0E-224 T 13-09-2016 THL1_RS05645 562bdd7881d3ea828f27cfef2f3a3fd1 486 SUPERFAMILY SSF51984 17 103 6.54E-29 T 13-09-2016 THL1_RS05645 562bdd7881d3ea828f27cfef2f3a3fd1 486 PANTHER PTHR23135:SF5 11 462 3.0E-224 T 13-09-2016 THL1_RS25015 a0a412cc91fb4af375f34f2908fdbc56 158 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 27 1.8E-6 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS25015 a0a412cc91fb4af375f34f2908fdbc56 158 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS25015 a0a412cc91fb4af375f34f2908fdbc56 158 PRINTS PR00885 Bacterial general secretion pathway protein H signature 116 131 2.7E-11 T 13-09-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 THL1_RS25015 a0a412cc91fb4af375f34f2908fdbc56 158 PRINTS PR00885 Bacterial general secretion pathway protein H signature 3 17 2.7E-11 T 13-09-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 THL1_RS25015 a0a412cc91fb4af375f34f2908fdbc56 158 PRINTS PR00885 Bacterial general secretion pathway protein H signature 18 32 2.7E-11 T 13-09-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 THL1_RS25015 a0a412cc91fb4af375f34f2908fdbc56 158 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 3 26 2.6E-6 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS25015 a0a412cc91fb4af375f34f2908fdbc56 158 Gene3D G3DSA:3.55.40.10 38 137 2.2E-18 T 13-09-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 THL1_RS25015 a0a412cc91fb4af375f34f2908fdbc56 158 SUPERFAMILY SSF54523 8 77 1.18E-10 T 13-09-2016 THL1_RS25015 a0a412cc91fb4af375f34f2908fdbc56 158 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 5 134 3.4E-15 T 13-09-2016 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 THL1_RS25015 a0a412cc91fb4af375f34f2908fdbc56 158 Pfam PF12019 Type II transport protein GspH 42 134 1.4E-4 T 13-09-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 THL1_RS18995 b1f693c902c43b7c8a4a8fc5067b58a1 249 PANTHER PTHR24322:SF343 14 141 1.8E-55 T 13-09-2016 THL1_RS18995 b1f693c902c43b7c8a4a8fc5067b58a1 249 PANTHER PTHR24322:SF343 158 190 1.8E-55 T 13-09-2016 THL1_RS18995 b1f693c902c43b7c8a4a8fc5067b58a1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.7E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18995 b1f693c902c43b7c8a4a8fc5067b58a1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.7E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18995 b1f693c902c43b7c8a4a8fc5067b58a1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.7E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18995 b1f693c902c43b7c8a4a8fc5067b58a1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.7E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18995 b1f693c902c43b7c8a4a8fc5067b58a1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.7E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18995 b1f693c902c43b7c8a4a8fc5067b58a1 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.7E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18995 b1f693c902c43b7c8a4a8fc5067b58a1 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.4E-13 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18995 b1f693c902c43b7c8a4a8fc5067b58a1 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.4E-13 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18995 b1f693c902c43b7c8a4a8fc5067b58a1 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 4.4E-13 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18995 b1f693c902c43b7c8a4a8fc5067b58a1 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 248 9.0E-65 T 13-09-2016 THL1_RS18995 b1f693c902c43b7c8a4a8fc5067b58a1 249 SUPERFAMILY SSF51735 8 248 3.26E-80 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18995 b1f693c902c43b7c8a4a8fc5067b58a1 249 Gene3D G3DSA:3.40.50.720 6 249 9.6E-82 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18995 b1f693c902c43b7c8a4a8fc5067b58a1 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 194 0.0081 T 13-09-2016 THL1_RS18995 b1f693c902c43b7c8a4a8fc5067b58a1 249 PANTHER PTHR24322 14 141 1.8E-55 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18995 b1f693c902c43b7c8a4a8fc5067b58a1 249 PANTHER PTHR24322 158 190 1.8E-55 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20595 9752e4582558c96d4f51121d9a901487 278 PANTHER PTHR10992 157 274 2.3E-55 T 13-09-2016 THL1_RS20595 9752e4582558c96d4f51121d9a901487 278 PANTHER PTHR10992 11 136 2.3E-55 T 13-09-2016 THL1_RS20595 9752e4582558c96d4f51121d9a901487 278 Pfam PF12146 Serine aminopeptidase, S33 24 260 2.6E-22 T 13-09-2016 IPR022742 Serine aminopeptidase, S33 THL1_RS20595 9752e4582558c96d4f51121d9a901487 278 Gene3D G3DSA:3.40.50.1820 4 273 2.9E-60 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS20595 9752e4582558c96d4f51121d9a901487 278 PRINTS PR00412 Epoxide hydrolase signature 249 271 4.1E-5 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS20595 9752e4582558c96d4f51121d9a901487 278 PRINTS PR00412 Epoxide hydrolase signature 51 66 4.1E-5 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS20595 9752e4582558c96d4f51121d9a901487 278 PRINTS PR00412 Epoxide hydrolase signature 31 49 4.1E-5 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS20595 9752e4582558c96d4f51121d9a901487 278 PANTHER PTHR10992:SF868 157 274 2.3E-55 T 13-09-2016 THL1_RS20595 9752e4582558c96d4f51121d9a901487 278 PANTHER PTHR10992:SF868 11 136 2.3E-55 T 13-09-2016 THL1_RS20595 9752e4582558c96d4f51121d9a901487 278 SUPERFAMILY SSF53474 5 271 2.48E-47 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS20595 9752e4582558c96d4f51121d9a901487 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 1.8E-5 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS20595 9752e4582558c96d4f51121d9a901487 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 1.8E-5 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS20595 9752e4582558c96d4f51121d9a901487 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 218 232 1.8E-5 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS19820 3340ca4a15139639b6d8d013620ce3b2 472 Gene3D G3DSA:3.40.640.10 76 354 3.9E-74 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS19820 3340ca4a15139639b6d8d013620ce3b2 472 Gene3D G3DSA:3.90.1150.10 15 75 3.9E-40 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS19820 3340ca4a15139639b6d8d013620ce3b2 472 Gene3D G3DSA:3.90.1150.10 356 459 3.9E-40 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS19820 3340ca4a15139639b6d8d013620ce3b2 472 PIRSF PIRSF000521 21 459 1.0E-28 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS19820 3340ca4a15139639b6d8d013620ce3b2 472 SUPERFAMILY SSF53383 21 456 1.77E-114 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS19820 3340ca4a15139639b6d8d013620ce3b2 472 Pfam PF00202 Aminotransferase class-III 38 456 1.9E-93 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS19820 3340ca4a15139639b6d8d013620ce3b2 472 PANTHER PTHR11986:SF72 17 464 3.0E-255 T 13-09-2016 THL1_RS19820 3340ca4a15139639b6d8d013620ce3b2 472 PANTHER PTHR11986 17 464 3.0E-255 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS01465 a232e8bc37b005957ff837145a25bd71 155 Pfam PF10027 Predicted integral membrane protein (DUF2269) 6 154 1.4E-39 T 13-09-2016 IPR018729 Protein of unknown function DUF2269, transmembrane THL1_RS03290 fcfe972fc4c306d6be3d7083dc18541c 282 SUPERFAMILY SSF53850 9 268 1.27E-45 T 13-09-2016 THL1_RS03290 fcfe972fc4c306d6be3d7083dc18541c 282 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 267 4.6E-39 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS03290 fcfe972fc4c306d6be3d7083dc18541c 282 SMART SM00062 36 269 3.3E-36 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS03290 fcfe972fc4c306d6be3d7083dc18541c 282 PANTHER PTHR18966 32 271 3.9E-16 T 13-09-2016 THL1_RS03290 fcfe972fc4c306d6be3d7083dc18541c 282 PANTHER PTHR18966:SF152 32 271 3.9E-16 T 13-09-2016 THL1_RS03290 fcfe972fc4c306d6be3d7083dc18541c 282 Gene3D G3DSA:3.40.190.10 18 140 1.5E-28 T 13-09-2016 THL1_RS03290 fcfe972fc4c306d6be3d7083dc18541c 282 Gene3D G3DSA:3.40.190.10 141 223 1.2E-17 T 13-09-2016 THL1_RS04225 96506fee87efa0408fb58d8b383cb65a 155 PANTHER PTHR33603 1 155 6.6E-64 T 13-09-2016 THL1_RS04225 96506fee87efa0408fb58d8b383cb65a 155 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 155 27.614 T 13-09-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS04225 96506fee87efa0408fb58d8b383cb65a 155 SUPERFAMILY SSF75217 1 154 3.19E-47 T 13-09-2016 IPR029028 Alpha/beta knot methyltransferases THL1_RS04225 96506fee87efa0408fb58d8b383cb65a 155 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 155 1.7E-60 T 13-09-2016 IPR016051 Ribosomal RNA large subunit methyltransferase H GO:0005737|GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS04225 96506fee87efa0408fb58d8b383cb65a 155 Gene3D G3DSA:3.40.1280.10 2 155 1.8E-50 T 13-09-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THL1_RS04225 96506fee87efa0408fb58d8b383cb65a 155 PIRSF PIRSF004505 1 155 2.6E-41 T 13-09-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS04225 96506fee87efa0408fb58d8b383cb65a 155 PANTHER PTHR33603:SF1 1 155 6.6E-64 T 13-09-2016 THL1_RS04225 96506fee87efa0408fb58d8b383cb65a 155 Pfam PF02590 Predicted SPOUT methyltransferase 2 154 4.7E-46 T 13-09-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS12840 b330726f29430edfb14782fdc89917af 179 Gene3D G3DSA:2.60.40.420 34 179 5.6E-36 T 13-09-2016 IPR008972 Cupredoxin THL1_RS12840 b330726f29430edfb14782fdc89917af 179 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 45 179 4.0E-8 T 13-09-2016 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 THL1_RS12840 b330726f29430edfb14782fdc89917af 179 SUPERFAMILY SSF49503 43 179 6.11E-25 T 13-09-2016 IPR008972 Cupredoxin THL1_RS20565 9c2f8594347adcd66b366895adbde846 367 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 4 199 4.4E-72 T 13-09-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS20565 9c2f8594347adcd66b366895adbde846 367 PANTHER PTHR21327:SF6 1 364 4.3E-133 T 13-09-2016 THL1_RS20565 9c2f8594347adcd66b366895adbde846 367 PANTHER PTHR21327 1 364 4.3E-133 T 13-09-2016 THL1_RS20565 9c2f8594347adcd66b366895adbde846 367 SUPERFAMILY SSF55821 2 202 2.08E-84 T 13-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain THL1_RS20565 9c2f8594347adcd66b366895adbde846 367 Pfam PF00925 GTP cyclohydrolase II 209 364 1.1E-25 T 13-09-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 THL1_RS20565 9c2f8594347adcd66b366895adbde846 367 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 37.906 T 13-09-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS20565 9c2f8594347adcd66b366895adbde846 367 PIRSF PIRSF001259 1 367 1.2E-111 T 13-09-2016 THL1_RS20565 9c2f8594347adcd66b366895adbde846 367 SUPERFAMILY SSF142695 205 364 7.59E-34 T 13-09-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 THL1_RS20565 9c2f8594347adcd66b366895adbde846 367 Gene3D G3DSA:3.90.870.10 1 209 3.9E-96 T 13-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain THL1_RS20565 9c2f8594347adcd66b366895adbde846 367 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 7 198 1.8E-81 T 13-09-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 SUPERFAMILY SSF50465 331 433 6.23E-34 T 13-09-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 SUPERFAMILY SSF50447 243 328 6.63E-24 T 13-09-2016 IPR009000 Translation protein, beta-barrel domain THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 PANTHER PTHR23115 10 51 1.5E-71 T 13-09-2016 THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 PANTHER PTHR23115 73 346 1.5E-71 T 13-09-2016 THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 80 95 - T 13-09-2016 IPR031157 Tr-type G domain, conserved site THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 Pfam PF00009 Elongation factor Tu GTP binding domain 23 225 1.0E-44 T 13-09-2016 THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 Gene3D G3DSA:3.40.50.300 11 233 4.2E-70 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 Gene3D G3DSA:2.40.30.10 243 327 1.3E-14 T 13-09-2016 THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 Gene3D G3DSA:2.40.30.10 330 433 2.2E-7 T 13-09-2016 THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 31 211 2.0E-14 T 13-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 Gene3D G3DSA:3.40.50.300 448 633 9.7E-56 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 PRINTS PR00315 GTP-binding elongation factor signature 107 117 3.1E-13 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 PRINTS PR00315 GTP-binding elongation factor signature 26 39 3.1E-13 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 PRINTS PR00315 GTP-binding elongation factor signature 160 169 3.1E-13 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 PRINTS PR00315 GTP-binding elongation factor signature 87 95 3.1E-13 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 PRINTS PR00315 GTP-binding elongation factor signature 123 134 3.1E-13 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 25 432 1.7E-207 T 13-09-2016 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 SUPERFAMILY SSF52540 18 234 7.41E-61 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 Pfam PF01583 Adenylylsulphate kinase 464 613 1.3E-49 T 13-09-2016 THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 SUPERFAMILY SSF52540 463 630 2.44E-28 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 463 631 31.579 T 13-09-2016 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: REACT_13433|UniPathway: UPA00140 THL1_RS05480 60d7d49af5d4d19034876495c5013883 633 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 16 461 55.074 T 13-09-2016 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 THL1_RS17460 1fa332305d6ddf336f9204e1df6dac5a 555 Gene3D G3DSA:3.30.300.30 443 544 1.5E-26 T 13-09-2016 THL1_RS17460 1fa332305d6ddf336f9204e1df6dac5a 555 Gene3D G3DSA:3.40.50.980 26 208 7.1E-32 T 13-09-2016 THL1_RS17460 1fa332305d6ddf336f9204e1df6dac5a 555 PANTHER PTHR24095 25 546 1.1E-127 T 13-09-2016 THL1_RS17460 1fa332305d6ddf336f9204e1df6dac5a 555 Pfam PF13193 AMP-binding enzyme C-terminal domain 457 534 3.7E-12 T 13-09-2016 IPR025110 AMP-binding enzyme C-terminal domain THL1_RS17460 1fa332305d6ddf336f9204e1df6dac5a 555 Gene3D G3DSA:2.30.38.10 370 442 9.5E-22 T 13-09-2016 THL1_RS17460 1fa332305d6ddf336f9204e1df6dac5a 555 ProSitePatterns PS00455 Putative AMP-binding domain signature. 203 214 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS17460 1fa332305d6ddf336f9204e1df6dac5a 555 Pfam PF00501 AMP-binding enzyme 32 448 1.2E-85 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS17460 1fa332305d6ddf336f9204e1df6dac5a 555 SUPERFAMILY SSF56801 24 547 9.68E-135 T 13-09-2016 THL1_RS17460 1fa332305d6ddf336f9204e1df6dac5a 555 Gene3D G3DSA:3.40.50.980 209 360 3.6E-31 T 13-09-2016 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 426 439 3.5E-34 T 13-09-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 400 415 3.5E-34 T 13-09-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 333 349 3.5E-34 T 13-09-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 294 311 3.5E-34 T 13-09-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 Hamap MF_01953 Urease subunit alpha [ureC]. 1 566 57.692 T 13-09-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 SUPERFAMILY SSF51556 128 431 6.58E-206 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 SUPERFAMILY SSF51556 480 566 6.58E-206 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 PANTHER PTHR22642 319 500 7.7E-264 T 13-09-2016 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 Gene3D G3DSA:3.20.20.140 487 564 5.8E-216 T 13-09-2016 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 Gene3D G3DSA:3.20.20.140 143 428 5.8E-216 T 13-09-2016 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 Pfam PF01979 Amidohydrolase family 124 449 1.7E-80 T 13-09-2016 IPR006680 Amidohydrolase-related GO:0016787 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 SUPERFAMILY SSF51338 421 476 1.4E-6 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 PANTHER PTHR22642:SF7 23 295 7.7E-264 T 13-09-2016 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 ProSitePatterns PS00145 Urease active site. 316 332 - T 13-09-2016 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 2 566 2.7E-300 T 13-09-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 ProSitePatterns PS01120 Urease nickel ligands signature. 126 139 - T 13-09-2016 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 Gene3D G3DSA:2.30.40.10 67 142 2.8E-15 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 PANTHER PTHR22642:SF7 319 500 7.7E-264 T 13-09-2016 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 SUPERFAMILY SSF51338 2 176 1.38E-62 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 Pfam PF00449 Urease alpha-subunit, N-terminal domain 1 118 4.0E-56 T 13-09-2016 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25580 69a99e65ac601e1d367d578e59809583 566 PANTHER PTHR22642 23 295 7.7E-264 T 13-09-2016 THL1_RS01375 d3f0b75279f9f17f7d77ffec7dbe4775 180 SUPERFAMILY SSF53850 3 170 5.66E-25 T 13-09-2016 THL1_RS01375 d3f0b75279f9f17f7d77ffec7dbe4775 180 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 53 66 - T 13-09-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 THL1_RS01375 d3f0b75279f9f17f7d77ffec7dbe4775 180 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 32 114 5.5E-16 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS01375 d3f0b75279f9f17f7d77ffec7dbe4775 180 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 128 169 4.9E-6 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS01375 d3f0b75279f9f17f7d77ffec7dbe4775 180 Gene3D G3DSA:3.40.190.10 28 171 1.8E-25 T 13-09-2016 THL1_RS27830 1d4b6b9ebf351919a9d85d1cca66ba61 151 SUPERFAMILY SSF51283 2 149 3.14E-53 T 13-09-2016 IPR029054 dUTPase-like THL1_RS27830 1d4b6b9ebf351919a9d85d1cca66ba61 151 Gene3D G3DSA:2.70.40.10 7 149 6.6E-53 T 13-09-2016 IPR029054 dUTPase-like THL1_RS27830 1d4b6b9ebf351919a9d85d1cca66ba61 151 Pfam PF00692 dUTPase 16 149 4.9E-40 T 13-09-2016 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 THL1_RS27830 1d4b6b9ebf351919a9d85d1cca66ba61 151 TIGRFAM TIGR00576 dut: dUTP diphosphatase 10 150 2.5E-48 T 13-09-2016 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|UniPathway: UPA00610 THL1_RS27830 1d4b6b9ebf351919a9d85d1cca66ba61 151 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 6 150 33.473 T 13-09-2016 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7206|UniPathway: UPA00610 THL1_RS27830 1d4b6b9ebf351919a9d85d1cca66ba61 151 PANTHER PTHR11241 6 149 4.9E-52 T 13-09-2016 THL1_RS10540 5cf6d524ef146d68a934fe10e259c5b5 531 PANTHER PTHR11748 57 530 2.3E-139 T 13-09-2016 THL1_RS10540 5cf6d524ef146d68a934fe10e259c5b5 531 Gene3D G3DSA:3.30.465.10 147 263 7.9E-13 T 13-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THL1_RS10540 5cf6d524ef146d68a934fe10e259c5b5 531 SUPERFAMILY SSF56176 39 263 2.01E-41 T 13-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THL1_RS10540 5cf6d524ef146d68a934fe10e259c5b5 531 PANTHER PTHR11748:SF3 57 530 2.3E-139 T 13-09-2016 IPR025650 Alkyldihydroxyacetonephosphate synthase GO:0008609|GO:0008610 KEGG: 00565+2.5.1.26|UniPathway: UPA00781 THL1_RS10540 5cf6d524ef146d68a934fe10e259c5b5 531 SUPERFAMILY SSF55103 270 529 6.38E-35 T 13-09-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 THL1_RS10540 5cf6d524ef146d68a934fe10e259c5b5 531 Pfam PF02913 FAD linked oxidases, C-terminal domain 266 526 1.0E-38 T 13-09-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 THL1_RS10540 5cf6d524ef146d68a934fe10e259c5b5 531 Pfam PF01565 FAD binding domain 88 215 5.2E-29 T 13-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THL1_RS10540 5cf6d524ef146d68a934fe10e259c5b5 531 Gene3D G3DSA:3.30.43.10 57 146 7.2E-13 T 13-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 217 280 9.5E-18 T 13-09-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 SUPERFAMILY SSF55874 283 463 1.15E-38 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 Gene3D G3DSA:2.40.50.180 488 553 2.3E-10 T 13-09-2016 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 327 464 5.0E-16 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 Gene3D G3DSA:1.10.287.560 217 281 7.9E-23 T 13-09-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 Gene3D G3DSA:1.20.120.160 2 127 2.0E-43 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 SUPERFAMILY SSF50341 464 597 2.35E-31 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 Gene3D G3DSA:3.30.565.10 282 464 1.7E-35 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 Pfam PF01627 Hpt domain 7 97 2.9E-21 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 Gene3D G3DSA:2.30.30.40 465 486 1.5E-24 T 13-09-2016 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 Gene3D G3DSA:2.30.30.40 554 597 1.5E-24 T 13-09-2016 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 SMART SM01231 217 280 1.2E-23 T 13-09-2016 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 462 3.4E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 384 3.4E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 419 3.4E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 443 3.4E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 SMART SM00387 325 465 4.0E-25 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 PANTHER PTHR22617 5 597 1.8E-241 T 13-09-2016 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 PANTHER PTHR22617:SF20 5 597 1.8E-241 T 13-09-2016 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 SMART SM00073 5 102 2.3E-28 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 SUPERFAMILY SSF47226 5 127 3.66E-33 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 SMART SM00260 457 598 3.9E-36 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 Pfam PF01584 CheW-like domain 470 597 1.9E-26 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS07195 bf24cb7f01933962ff2efebc70e17b2f 612 SUPERFAMILY SSF47384 218 281 1.92E-15 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS20010 08cef0a1bacdcee12cde359415150d20 870 PANTHER PTHR32552 132 870 1.5E-217 T 13-09-2016 THL1_RS20010 08cef0a1bacdcee12cde359415150d20 870 Pfam PF07660 Secretin and TonB N terminus short domain 76 125 3.4E-8 T 13-09-2016 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 THL1_RS20010 08cef0a1bacdcee12cde359415150d20 870 TIGRFAM TIGR01785 TonB-hemin: TonB-dependent heme/hemoglobin receptor family protein 133 866 8.0E-121 T 13-09-2016 IPR011276 TonB-dependent haem/haemoglobin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 THL1_RS20010 08cef0a1bacdcee12cde359415150d20 870 Gene3D G3DSA:2.40.170.20 263 867 1.0E-110 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS20010 08cef0a1bacdcee12cde359415150d20 870 PANTHER PTHR32552:SF18 132 870 1.5E-217 T 13-09-2016 THL1_RS20010 08cef0a1bacdcee12cde359415150d20 870 Pfam PF00593 TonB dependent receptor 596 867 2.7E-36 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS20010 08cef0a1bacdcee12cde359415150d20 870 SMART SM00965 75 126 1.1E-12 T 13-09-2016 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 THL1_RS20010 08cef0a1bacdcee12cde359415150d20 870 Pfam PF07715 TonB-dependent Receptor Plug Domain 150 257 2.0E-26 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS20010 08cef0a1bacdcee12cde359415150d20 870 TIGRFAM TIGR01786 TonB-hemlactrns: TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein 136 867 3.5E-156 T 13-09-2016 IPR010949 TonB-dependent haemoglobin/transferrin/lactoferrin receptor GO:0004872|GO:0005215|GO:0006810|GO:0019867 THL1_RS20010 08cef0a1bacdcee12cde359415150d20 870 Gene3D G3DSA:2.170.130.10 146 262 2.4E-36 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS20010 08cef0a1bacdcee12cde359415150d20 870 SUPERFAMILY SSF56935 525 866 5.13E-121 T 13-09-2016 THL1_RS20010 08cef0a1bacdcee12cde359415150d20 870 SUPERFAMILY SSF56935 137 497 5.13E-121 T 13-09-2016 THL1_RS14720 42e1edc3b8703ba1010b98ee360c4c50 309 PANTHER PTHR10996 41 304 2.9E-80 T 13-09-2016 THL1_RS14720 42e1edc3b8703ba1010b98ee360c4c50 309 PANTHER PTHR10996:SF114 41 304 2.9E-80 T 13-09-2016 THL1_RS14720 42e1edc3b8703ba1010b98ee360c4c50 309 SUPERFAMILY SSF52283 36 123 2.11E-10 T 13-09-2016 THL1_RS14720 42e1edc3b8703ba1010b98ee360c4c50 309 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 104 274 2.6E-39 T 13-09-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 THL1_RS14720 42e1edc3b8703ba1010b98ee360c4c50 309 SUPERFAMILY SSF51735 95 275 1.65E-42 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS14720 42e1edc3b8703ba1010b98ee360c4c50 309 Gene3D G3DSA:3.40.50.720 95 275 4.8E-48 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS08520 b9ef4411ab34d61ac2b8421686cb5a2e 233 PANTHER PTHR24220 3 232 6.0E-134 T 13-09-2016 THL1_RS08520 b9ef4411ab34d61ac2b8421686cb5a2e 233 Pfam PF00005 ABC transporter 17 161 1.1E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS08520 b9ef4411ab34d61ac2b8421686cb5a2e 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS08520 b9ef4411ab34d61ac2b8421686cb5a2e 233 PIRSF PIRSF039137 1 233 4.1E-104 T 13-09-2016 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 THL1_RS08520 b9ef4411ab34d61ac2b8421686cb5a2e 233 SMART SM00382 26 212 2.0E-6 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS08520 b9ef4411ab34d61ac2b8421686cb5a2e 233 Gene3D G3DSA:3.40.50.300 1 229 1.3E-62 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08520 b9ef4411ab34d61ac2b8421686cb5a2e 233 SUPERFAMILY SSF52540 2 231 5.33E-61 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08520 b9ef4411ab34d61ac2b8421686cb5a2e 233 PANTHER PTHR24220:SF568 3 232 6.0E-134 T 13-09-2016 THL1_RS09565 18614e5cb2723e1fbe1ca1b5d99842d7 440 SUPERFAMILY SSF52540 242 433 1.82E-19 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09565 18614e5cb2723e1fbe1ca1b5d99842d7 440 SUPERFAMILY SSF52540 146 193 1.82E-19 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09565 18614e5cb2723e1fbe1ca1b5d99842d7 440 Gene3D G3DSA:1.10.10.10 41 108 1.5E-4 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09565 18614e5cb2723e1fbe1ca1b5d99842d7 440 Gene3D G3DSA:3.40.50.300 145 178 2.5E-13 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09565 18614e5cb2723e1fbe1ca1b5d99842d7 440 Gene3D G3DSA:3.40.50.300 240 368 2.5E-13 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09565 18614e5cb2723e1fbe1ca1b5d99842d7 440 SMART SM00382 165 352 8.7E-5 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS09565 18614e5cb2723e1fbe1ca1b5d99842d7 440 Gene3D G3DSA:3.40.50.300 179 231 3.8E-4 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27775 10d687347ce455e48e80b33c0b38aae8 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 27 38 3.6E-21 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS27775 10d687347ce455e48e80b33c0b38aae8 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 57 3.6E-21 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS27775 10d687347ce455e48e80b33c0b38aae8 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 11 27 3.6E-21 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS27775 10d687347ce455e48e80b33c0b38aae8 162 Pfam PF01037 Lrp/AsnC ligand binding domain 77 151 2.5E-21 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS27775 10d687347ce455e48e80b33c0b38aae8 162 Gene3D G3DSA:3.30.70.920 64 160 5.0E-32 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS27775 10d687347ce455e48e80b33c0b38aae8 162 Gene3D G3DSA:1.10.10.10 12 63 5.6E-26 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS27775 10d687347ce455e48e80b33c0b38aae8 162 PANTHER PTHR30154 3 160 1.4E-92 T 13-09-2016 THL1_RS27775 10d687347ce455e48e80b33c0b38aae8 162 SUPERFAMILY SSF54909 73 160 5.9E-21 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS27775 10d687347ce455e48e80b33c0b38aae8 162 Pfam PF13404 AsnC-type helix-turn-helix domain 11 52 1.4E-20 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS27775 10d687347ce455e48e80b33c0b38aae8 162 PANTHER PTHR30154:SF0 3 160 1.4E-92 T 13-09-2016 THL1_RS27775 10d687347ce455e48e80b33c0b38aae8 162 SUPERFAMILY SSF46785 10 69 5.53E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS27775 10d687347ce455e48e80b33c0b38aae8 162 SMART SM00344 11 120 1.0E-48 T 13-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 THL1_RS27775 10d687347ce455e48e80b33c0b38aae8 162 ProSitePatterns PS00519 AsnC-type HTH domain signature. 29 55 - T 13-09-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site THL1_RS12135 e1fb340ace2428eff49cfaf89d573475 352 Pfam PF00199 Catalase 61 338 7.2E-20 T 13-09-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS12135 e1fb340ace2428eff49cfaf89d573475 352 PANTHER PTHR11465 1 341 2.5E-103 T 13-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS12135 e1fb340ace2428eff49cfaf89d573475 352 PIRSF PIRSF000296 11 342 4.0E-117 T 13-09-2016 IPR024168 Catalase, SrpA-type, predicted THL1_RS12135 e1fb340ace2428eff49cfaf89d573475 352 Gene3D G3DSA:2.40.180.10 39 345 2.1E-73 T 13-09-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS12135 e1fb340ace2428eff49cfaf89d573475 352 PANTHER PTHR11465:SF16 1 341 2.5E-103 T 13-09-2016 THL1_RS12135 e1fb340ace2428eff49cfaf89d573475 352 SMART SM01060 24 352 2.4E-5 T 13-09-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS12135 e1fb340ace2428eff49cfaf89d573475 352 SUPERFAMILY SSF56634 29 340 7.85E-85 T 13-09-2016 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS16075 554c73e230903eeb5f06a83b2c223837 93 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 19 74 1.7E-6 T 13-09-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THL1_RS16075 554c73e230903eeb5f06a83b2c223837 93 SUPERFAMILY SSF143120 12 87 1.29E-7 T 13-09-2016 THL1_RS20295 e86f6ad4e40ac1bebc1048b44eb97e0d 573 Gene3D G3DSA:1.10.3720.10 31 283 6.8E-44 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS20295 e86f6ad4e40ac1bebc1048b44eb97e0d 573 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 281 7.4E-11 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS20295 e86f6ad4e40ac1bebc1048b44eb97e0d 573 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 377 557 1.9E-10 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS20295 e86f6ad4e40ac1bebc1048b44eb97e0d 573 SUPERFAMILY SSF161098 27 282 9.42E-44 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS20295 e86f6ad4e40ac1bebc1048b44eb97e0d 573 TIGRFAM TIGR03262 PhnU2: putative 2-aminoethylphosphonate ABC transporter, permease protein 32 567 6.8E-229 T 13-09-2016 IPR017664 2-aminoethylphosphonate ABC transport system, permease protein, putative THL1_RS20295 e86f6ad4e40ac1bebc1048b44eb97e0d 573 PANTHER PTHR30193 36 290 1.4E-59 T 13-09-2016 THL1_RS20295 e86f6ad4e40ac1bebc1048b44eb97e0d 573 Gene3D G3DSA:1.10.3720.10 299 551 1.2E-28 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS20295 e86f6ad4e40ac1bebc1048b44eb97e0d 573 SUPERFAMILY SSF161098 303 554 4.77E-32 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS20295 e86f6ad4e40ac1bebc1048b44eb97e0d 573 PANTHER PTHR30193:SF3 36 290 1.4E-59 T 13-09-2016 THL1_RS22730 b3d2969b20c2878b1ac8bb151ffd9302 307 Pfam PF00005 ABC transporter 17 160 3.5E-29 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS22730 b3d2969b20c2878b1ac8bb151ffd9302 307 SMART SM00382 26 216 4.4E-14 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS22730 b3d2969b20c2878b1ac8bb151ffd9302 307 PANTHER PTHR24220:SF193 3 305 7.8E-92 T 13-09-2016 THL1_RS22730 b3d2969b20c2878b1ac8bb151ffd9302 307 Gene3D G3DSA:3.40.50.300 1 230 5.9E-68 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22730 b3d2969b20c2878b1ac8bb151ffd9302 307 PANTHER PTHR24220 3 305 7.8E-92 T 13-09-2016 THL1_RS22730 b3d2969b20c2878b1ac8bb151ffd9302 307 SUPERFAMILY SSF52540 2 224 1.96E-61 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21240 076c7919856cb9c89a597c3ff51005c7 497 PANTHER PTHR11819 4 487 6.6E-191 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS21240 076c7919856cb9c89a597c3ff51005c7 497 PANTHER PTHR11819:SF148 4 487 6.6E-191 T 13-09-2016 THL1_RS21240 076c7919856cb9c89a597c3ff51005c7 497 Pfam PF00474 Sodium:solute symporter family 35 437 2.2E-134 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS21240 076c7919856cb9c89a597c3ff51005c7 497 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 437 8.8E-121 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS21240 076c7919856cb9c89a597c3ff51005c7 497 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 157 182 - T 13-09-2016 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 THL1_RS21240 076c7919856cb9c89a597c3ff51005c7 497 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 7 492 1.4E-224 T 13-09-2016 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 THL1_RS12575 2687bf5163fc466c2b90a831b26f251f 68 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 63 1.4E-19 T 13-09-2016 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 THL1_RS12575 2687bf5163fc466c2b90a831b26f251f 68 Gene3D G3DSA:3.30.429.20 1 65 1.2E-25 T 13-09-2016 THL1_RS12575 2687bf5163fc466c2b90a831b26f251f 68 PANTHER PTHR35530:SF1 1 66 2.8E-20 T 13-09-2016 THL1_RS12575 2687bf5163fc466c2b90a831b26f251f 68 Pfam PF01361 Tautomerase enzyme 2 56 2.9E-17 T 13-09-2016 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 THL1_RS12575 2687bf5163fc466c2b90a831b26f251f 68 SUPERFAMILY SSF55331 2 65 1.4E-21 T 13-09-2016 IPR014347 Tautomerase/MIF superfamily THL1_RS12575 2687bf5163fc466c2b90a831b26f251f 68 PANTHER PTHR35530 1 66 2.8E-20 T 13-09-2016 THL1_RS27815 0059cc1272128b136abe1516a30aa021 524 PANTHER PTHR30290:SF14 15 523 8.7E-195 T 13-09-2016 THL1_RS27815 0059cc1272128b136abe1516a30aa021 524 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 62 442 1.2E-94 T 13-09-2016 IPR000914 Solute-binding protein family 5 domain THL1_RS27815 0059cc1272128b136abe1516a30aa021 524 PIRSF PIRSF002741 14 524 1.8E-116 T 13-09-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 THL1_RS27815 0059cc1272128b136abe1516a30aa021 524 SUPERFAMILY SSF53850 19 523 1.18E-146 T 13-09-2016 THL1_RS27815 0059cc1272128b136abe1516a30aa021 524 PANTHER PTHR30290 15 523 8.7E-195 T 13-09-2016 THL1_RS27815 0059cc1272128b136abe1516a30aa021 524 Gene3D G3DSA:3.90.76.10 28 208 2.0E-45 T 13-09-2016 THL1_RS27815 0059cc1272128b136abe1516a30aa021 524 Gene3D G3DSA:3.10.105.10 279 494 2.4E-62 T 13-09-2016 THL1_RS16235 e52ca141aada2d043b5ed244138ce975 118 Pfam PF05717 IS66 Orf2 like protein 10 104 1.7E-30 T 13-09-2016 IPR008878 Transposase IS66, Orf2 THL1_RS16235 e52ca141aada2d043b5ed244138ce975 118 PANTHER PTHR36455 2 118 1.9E-18 T 13-09-2016 THL1_RS09895 e52ca141aada2d043b5ed244138ce975 118 Pfam PF05717 IS66 Orf2 like protein 10 104 1.7E-30 T 13-09-2016 IPR008878 Transposase IS66, Orf2 THL1_RS09895 e52ca141aada2d043b5ed244138ce975 118 PANTHER PTHR36455 2 118 1.9E-18 T 13-09-2016 THL1_RS08875 e52ca141aada2d043b5ed244138ce975 118 Pfam PF05717 IS66 Orf2 like protein 10 104 1.7E-30 T 13-09-2016 IPR008878 Transposase IS66, Orf2 THL1_RS08875 e52ca141aada2d043b5ed244138ce975 118 PANTHER PTHR36455 2 118 1.9E-18 T 13-09-2016 THL1_RS09880 e52ca141aada2d043b5ed244138ce975 118 Pfam PF05717 IS66 Orf2 like protein 10 104 1.7E-30 T 13-09-2016 IPR008878 Transposase IS66, Orf2 THL1_RS09880 e52ca141aada2d043b5ed244138ce975 118 PANTHER PTHR36455 2 118 1.9E-18 T 13-09-2016 THL1_RS05450 e52ca141aada2d043b5ed244138ce975 118 Pfam PF05717 IS66 Orf2 like protein 10 104 1.7E-30 T 13-09-2016 IPR008878 Transposase IS66, Orf2 THL1_RS05450 e52ca141aada2d043b5ed244138ce975 118 PANTHER PTHR36455 2 118 1.9E-18 T 13-09-2016 THL1_RS26645 e52ca141aada2d043b5ed244138ce975 118 Pfam PF05717 IS66 Orf2 like protein 10 104 1.7E-30 T 13-09-2016 IPR008878 Transposase IS66, Orf2 THL1_RS26645 e52ca141aada2d043b5ed244138ce975 118 PANTHER PTHR36455 2 118 1.9E-18 T 13-09-2016 THL1_RS26945 e52ca141aada2d043b5ed244138ce975 118 Pfam PF05717 IS66 Orf2 like protein 10 104 1.7E-30 T 13-09-2016 IPR008878 Transposase IS66, Orf2 THL1_RS26945 e52ca141aada2d043b5ed244138ce975 118 PANTHER PTHR36455 2 118 1.9E-18 T 13-09-2016 THL1_RS08860 e52ca141aada2d043b5ed244138ce975 118 Pfam PF05717 IS66 Orf2 like protein 10 104 1.7E-30 T 13-09-2016 IPR008878 Transposase IS66, Orf2 THL1_RS08860 e52ca141aada2d043b5ed244138ce975 118 PANTHER PTHR36455 2 118 1.9E-18 T 13-09-2016 THL1_RS16500 225429257d6a7d19cb96b8765bb977c1 527 PANTHER PTHR11699:SF10 1 519 1.0E-156 T 13-09-2016 THL1_RS16500 225429257d6a7d19cb96b8765bb977c1 527 Gene3D G3DSA:3.40.309.10 267 454 3.1E-48 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS16500 225429257d6a7d19cb96b8765bb977c1 527 SUPERFAMILY SSF53720 19 518 1.44E-96 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS16500 225429257d6a7d19cb96b8765bb977c1 527 Gene3D G3DSA:3.40.605.10 8 265 4.3E-47 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS16500 225429257d6a7d19cb96b8765bb977c1 527 PANTHER PTHR11699 1 519 1.0E-156 T 13-09-2016 THL1_RS16500 225429257d6a7d19cb96b8765bb977c1 527 Pfam PF00171 Aldehyde dehydrogenase family 19 459 1.3E-43 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS18030 4d480c3646622c708d9095e2a2088127 461 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 460 38.566 T 13-09-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 THL1_RS18030 4d480c3646622c708d9095e2a2088127 461 SMART SM00840 341 402 8.8E-25 T 13-09-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 THL1_RS18030 4d480c3646622c708d9095e2a2088127 461 Gene3D G3DSA:1.20.120.640 307 392 8.5E-25 T 13-09-2016 THL1_RS18030 4d480c3646622c708d9095e2a2088127 461 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 314 3.4E-133 T 13-09-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 THL1_RS18030 4d480c3646622c708d9095e2a2088127 461 Pfam PF09190 DALR domain 341 402 1.0E-20 T 13-09-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 THL1_RS18030 4d480c3646622c708d9095e2a2088127 461 PANTHER PTHR10890 1 461 3.1E-243 T 13-09-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 THL1_RS18030 4d480c3646622c708d9095e2a2088127 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.3E-30 T 13-09-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 THL1_RS18030 4d480c3646622c708d9095e2a2088127 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 223 244 1.3E-30 T 13-09-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 THL1_RS18030 4d480c3646622c708d9095e2a2088127 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.3E-30 T 13-09-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 THL1_RS18030 4d480c3646622c708d9095e2a2088127 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 192 210 1.3E-30 T 13-09-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 THL1_RS18030 4d480c3646622c708d9095e2a2088127 461 Gene3D G3DSA:3.40.50.620 21 306 7.0E-109 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS18030 4d480c3646622c708d9095e2a2088127 461 SUPERFAMILY SSF52374 4 314 4.61E-100 T 13-09-2016 THL1_RS18030 4d480c3646622c708d9095e2a2088127 461 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 458 3.4E-173 T 13-09-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 THL1_RS18030 4d480c3646622c708d9095e2a2088127 461 SUPERFAMILY SSF47323 317 459 9.29E-40 T 13-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS15445 87c82b5a84c69e5f37ccc3dbafae8efb 499 Pfam PF02321 Outer membrane efflux protein 73 273 2.2E-25 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS15445 87c82b5a84c69e5f37ccc3dbafae8efb 499 Pfam PF02321 Outer membrane efflux protein 298 480 2.6E-27 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS15445 87c82b5a84c69e5f37ccc3dbafae8efb 499 Gene3D G3DSA:1.20.1600.10 63 485 2.8E-113 T 13-09-2016 THL1_RS15445 87c82b5a84c69e5f37ccc3dbafae8efb 499 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 19 482 2.7E-127 T 13-09-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 THL1_RS15445 87c82b5a84c69e5f37ccc3dbafae8efb 499 SUPERFAMILY SSF56954 10 484 4.19E-111 T 13-09-2016 THL1_RS15445 87c82b5a84c69e5f37ccc3dbafae8efb 499 PANTHER PTHR30203 1 499 1.3E-220 T 13-09-2016 THL1_RS15445 87c82b5a84c69e5f37ccc3dbafae8efb 499 PANTHER PTHR30203:SF7 1 499 1.3E-220 T 13-09-2016 THL1_RS15910 580d5a457f872fe760cd8c37f066bca4 392 SUPERFAMILY SSF53901 3 270 3.54E-91 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15910 580d5a457f872fe760cd8c37f066bca4 392 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 13-09-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 THL1_RS15910 580d5a457f872fe760cd8c37f066bca4 392 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 13-09-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 THL1_RS15910 580d5a457f872fe760cd8c37f066bca4 392 Pfam PF00108 Thiolase, N-terminal domain 4 262 9.0E-105 T 13-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THL1_RS15910 580d5a457f872fe760cd8c37f066bca4 392 Gene3D G3DSA:3.40.47.10 3 123 1.3E-80 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15910 580d5a457f872fe760cd8c37f066bca4 392 Gene3D G3DSA:3.40.47.10 194 276 1.3E-80 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15910 580d5a457f872fe760cd8c37f066bca4 392 PANTHER PTHR18919:SF95 1 392 1.8E-235 T 13-09-2016 THL1_RS15910 580d5a457f872fe760cd8c37f066bca4 392 SUPERFAMILY SSF53901 272 392 1.33E-43 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15910 580d5a457f872fe760cd8c37f066bca4 392 PIRSF PIRSF000429 1 392 1.6E-133 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS15910 580d5a457f872fe760cd8c37f066bca4 392 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 13-09-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 THL1_RS15910 580d5a457f872fe760cd8c37f066bca4 392 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 1.5E-146 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS15910 580d5a457f872fe760cd8c37f066bca4 392 PANTHER PTHR18919 1 392 1.8E-235 T 13-09-2016 THL1_RS15910 580d5a457f872fe760cd8c37f066bca4 392 Gene3D G3DSA:3.40.47.10 277 391 4.8E-67 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15910 580d5a457f872fe760cd8c37f066bca4 392 Gene3D G3DSA:3.40.47.10 142 193 4.8E-67 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS15910 580d5a457f872fe760cd8c37f066bca4 392 Pfam PF02803 Thiolase, C-terminal domain 271 392 3.4E-52 T 13-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THL1_RS28180 e380e8114e2aff8fcf3bd9863990a1de 326 PRINTS PR00139 Asparaginase/glutaminase family signature 7 18 1.1E-12 T 13-09-2016 IPR006034 Asparaginase/glutaminase GO:0006520 THL1_RS28180 e380e8114e2aff8fcf3bd9863990a1de 326 PRINTS PR00139 Asparaginase/glutaminase family signature 82 100 1.1E-12 T 13-09-2016 IPR006034 Asparaginase/glutaminase GO:0006520 THL1_RS28180 e380e8114e2aff8fcf3bd9863990a1de 326 PRINTS PR00139 Asparaginase/glutaminase family signature 250 268 1.1E-12 T 13-09-2016 IPR006034 Asparaginase/glutaminase GO:0006520 THL1_RS28180 e380e8114e2aff8fcf3bd9863990a1de 326 SMART SM00870 6 313 6.0E-91 T 13-09-2016 IPR006034 Asparaginase/glutaminase GO:0006520 THL1_RS28180 e380e8114e2aff8fcf3bd9863990a1de 326 Pfam PF00710 Asparaginase, N-terminal 7 173 6.0E-44 T 13-09-2016 IPR027474 L-asparaginase, N-terminal THL1_RS28180 e380e8114e2aff8fcf3bd9863990a1de 326 SUPERFAMILY SSF53774 4 325 2.75E-85 T 13-09-2016 IPR006034 Asparaginase/glutaminase GO:0006520 THL1_RS28180 e380e8114e2aff8fcf3bd9863990a1de 326 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 9 17 - T 13-09-2016 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 THL1_RS28180 e380e8114e2aff8fcf3bd9863990a1de 326 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 83 93 - T 13-09-2016 IPR027475 Asparaginase/glutaminase, active site 2 THL1_RS28180 e380e8114e2aff8fcf3bd9863990a1de 326 PIRSF PIRSF001220 1 324 4.5E-77 T 13-09-2016 IPR006034 Asparaginase/glutaminase GO:0006520 THL1_RS28180 e380e8114e2aff8fcf3bd9863990a1de 326 Gene3D G3DSA:3.40.50.40 200 324 6.8E-36 T 13-09-2016 IPR027473 L-asparaginase, C-terminal domain THL1_RS28180 e380e8114e2aff8fcf3bd9863990a1de 326 Gene3D G3DSA:3.40.50.1170 4 173 2.5E-48 T 13-09-2016 IPR027474 L-asparaginase, N-terminal THL1_RS28180 e380e8114e2aff8fcf3bd9863990a1de 326 PANTHER PTHR11707:SF3 4 326 6.0E-93 T 13-09-2016 THL1_RS28180 e380e8114e2aff8fcf3bd9863990a1de 326 PANTHER PTHR11707 4 326 6.0E-93 T 13-09-2016 THL1_RS28180 e380e8114e2aff8fcf3bd9863990a1de 326 PIRSF PIRSF500176 3 322 2.9E-85 T 13-09-2016 THL1_RS18850 5129e00b17cbe30831b6566f253beb01 471 Gene3D G3DSA:2.60.40.10 352 468 2.0E-33 T 13-09-2016 IPR013783 Immunoglobulin-like fold THL1_RS18850 5129e00b17cbe30831b6566f253beb01 471 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 270 281 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS18850 5129e00b17cbe30831b6566f253beb01 471 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 39 468 4.7E-175 T 13-09-2016 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021 THL1_RS18850 5129e00b17cbe30831b6566f253beb01 471 Gene3D G3DSA:3.30.70.20 279 329 1.8E-7 T 13-09-2016 THL1_RS18850 5129e00b17cbe30831b6566f253beb01 471 Pfam PF12801 4Fe-4S binding domain 93 125 2.0E-5 T 13-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THL1_RS18850 5129e00b17cbe30831b6566f253beb01 471 Pfam PF13746 4Fe-4S dicluster domain 217 322 3.1E-45 T 13-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THL1_RS18850 5129e00b17cbe30831b6566f253beb01 471 PANTHER PTHR24960 3 390 3.8E-187 T 13-09-2016 THL1_RS18850 5129e00b17cbe30831b6566f253beb01 471 Gene3D G3DSA:1.10.1060.10 221 278 1.3E-7 T 13-09-2016 THL1_RS18850 5129e00b17cbe30831b6566f253beb01 471 SUPERFAMILY SSF54862 103 125 2.62E-32 T 13-09-2016 THL1_RS18850 5129e00b17cbe30831b6566f253beb01 471 SUPERFAMILY SSF54862 171 353 2.62E-32 T 13-09-2016 THL1_RS18850 5129e00b17cbe30831b6566f253beb01 471 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 352 468 2.1E-28 T 13-09-2016 IPR032879 FixG, C-terminal immunoglobulin-like domain THL1_RS18850 5129e00b17cbe30831b6566f253beb01 471 PANTHER PTHR24960:SF45 3 390 3.8E-187 T 13-09-2016 THL1_RS25255 831c6718cfd9bf3a855d5620cbc61ce3 78 PANTHER PTHR36582 1 67 1.6E-24 T 13-09-2016 THL1_RS25255 831c6718cfd9bf3a855d5620cbc61ce3 78 PANTHER PTHR36582:SF1 1 67 1.6E-24 T 13-09-2016 THL1_RS25255 831c6718cfd9bf3a855d5620cbc61ce3 78 Gene3D G3DSA:1.10.1220.10 4 41 1.3E-7 T 13-09-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THL1_RS25255 831c6718cfd9bf3a855d5620cbc61ce3 78 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 6 66 3.2E-5 T 13-09-2016 IPR022789 Antitoxin ParD THL1_RS25255 831c6718cfd9bf3a855d5620cbc61ce3 78 SUPERFAMILY SSF47598 1 44 6.45E-11 T 13-09-2016 IPR010985 Ribbon-helix-helix GO:0006355 THL1_RS25255 831c6718cfd9bf3a855d5620cbc61ce3 78 TIGRFAM TIGR02606 antidote_CC2985: putative addiction module antidote protein, CC2985 family 3 62 1.1E-14 T 13-09-2016 IPR022789 Antitoxin ParD THL1_RS16690 d40f0ea63b73bb0452bda5be5496360a 87 Gene3D G3DSA:3.40.30.10 8 65 3.4E-9 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS16690 d40f0ea63b73bb0452bda5be5496360a 87 Pfam PF13192 Thioredoxin domain 6 65 3.9E-9 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS16690 d40f0ea63b73bb0452bda5be5496360a 87 SUPERFAMILY SSF52833 5 68 1.94E-9 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS20540 5ce1f5374917239c7249c218bf2d0a9b 160 PANTHER PTHR21058 1 160 1.5E-70 T 13-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS20540 5ce1f5374917239c7249c218bf2d0a9b 160 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 17 152 2.0E-51 T 13-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS20540 5ce1f5374917239c7249c218bf2d0a9b 160 SUPERFAMILY SSF52121 14 156 2.09E-56 T 13-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS20540 5ce1f5374917239c7249c218bf2d0a9b 160 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 153 1.6E-53 T 13-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS20540 5ce1f5374917239c7249c218bf2d0a9b 160 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 11 156 30.3 T 13-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS20540 5ce1f5374917239c7249c218bf2d0a9b 160 Gene3D G3DSA:3.40.50.960 6 156 1.3E-60 T 13-09-2016 IPR002180 6,7-dimethyl-8-ribityllumazine synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS03155 2aa94d0c9dd03157aebfc63bfdc9c719 292 Pfam PF01555 DNA methylase 65 227 1.2E-27 T 13-09-2016 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 THL1_RS03155 2aa94d0c9dd03157aebfc63bfdc9c719 292 Gene3D G3DSA:3.40.50.150 41 222 7.9E-42 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS03155 2aa94d0c9dd03157aebfc63bfdc9c719 292 Gene3D G3DSA:3.40.50.150 268 289 7.9E-42 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS03155 2aa94d0c9dd03157aebfc63bfdc9c719 292 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 68 74 - T 13-09-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THL1_RS03155 2aa94d0c9dd03157aebfc63bfdc9c719 292 PANTHER PTHR13370:SF7 99 167 1.7E-19 T 13-09-2016 THL1_RS03155 2aa94d0c9dd03157aebfc63bfdc9c719 292 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 120 140 3.2E-7 T 13-09-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THL1_RS03155 2aa94d0c9dd03157aebfc63bfdc9c719 292 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 64 78 3.2E-7 T 13-09-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THL1_RS03155 2aa94d0c9dd03157aebfc63bfdc9c719 292 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 223 241 3.2E-7 T 13-09-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 THL1_RS03155 2aa94d0c9dd03157aebfc63bfdc9c719 292 PANTHER PTHR13370 99 167 1.7E-19 T 13-09-2016 THL1_RS03155 2aa94d0c9dd03157aebfc63bfdc9c719 292 PANTHER PTHR13370 42 74 1.7E-19 T 13-09-2016 THL1_RS03155 2aa94d0c9dd03157aebfc63bfdc9c719 292 PANTHER PTHR13370:SF7 42 74 1.7E-19 T 13-09-2016 THL1_RS03155 2aa94d0c9dd03157aebfc63bfdc9c719 292 SUPERFAMILY SSF53335 40 259 1.03E-47 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS02320 f115161626876bfb4daf62cb73d9d6af 217 SUPERFAMILY SSF50475 2 197 4.46E-46 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS02320 f115161626876bfb4daf62cb73d9d6af 217 Pfam PF01613 Flavin reductase like domain 23 173 7.2E-21 T 13-09-2016 IPR002563 Flavin reductase like domain GO:0010181 THL1_RS02320 f115161626876bfb4daf62cb73d9d6af 217 PANTHER PTHR33798:SF1 1 214 3.0E-79 T 13-09-2016 THL1_RS02320 f115161626876bfb4daf62cb73d9d6af 217 Gene3D G3DSA:2.30.110.10 3 197 1.3E-55 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS02320 f115161626876bfb4daf62cb73d9d6af 217 SMART SM00903 20 173 3.4E-26 T 13-09-2016 IPR002563 Flavin reductase like domain GO:0010181 THL1_RS02320 f115161626876bfb4daf62cb73d9d6af 217 PANTHER PTHR33798 1 214 3.0E-79 T 13-09-2016 THL1_RS21695 5c13707680176c264d199c2260d996eb 958 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 8 955 26.005 T 13-09-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2 THL1_RS21695 5c13707680176c264d199c2260d996eb 958 PANTHER PTHR11773:SF1 8 957 0.0 T 13-09-2016 THL1_RS21695 5c13707680176c264d199c2260d996eb 958 Pfam PF02347 Glycine cleavage system P-protein 477 735 7.8E-11 T 13-09-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 THL1_RS21695 5c13707680176c264d199c2260d996eb 958 Pfam PF02347 Glycine cleavage system P-protein 17 440 3.1E-178 T 13-09-2016 IPR020580 Glycine cleavage system P-protein, N-terminal GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 THL1_RS21695 5c13707680176c264d199c2260d996eb 958 SUPERFAMILY SSF53383 928 950 1.64E-105 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS21695 5c13707680176c264d199c2260d996eb 958 SUPERFAMILY SSF53383 462 886 1.64E-105 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS21695 5c13707680176c264d199c2260d996eb 958 PANTHER PTHR11773 8 957 0.0 T 13-09-2016 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2 THL1_RS21695 5c13707680176c264d199c2260d996eb 958 Gene3D G3DSA:3.40.640.10 502 741 5.0E-41 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS21695 5c13707680176c264d199c2260d996eb 958 Gene3D G3DSA:3.40.640.10 86 302 4.3E-14 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS21695 5c13707680176c264d199c2260d996eb 958 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 17 949 0.0 T 13-09-2016 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2 THL1_RS21695 5c13707680176c264d199c2260d996eb 958 SUPERFAMILY SSF53383 17 441 3.35E-99 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS07395 820b478b4ea556668a6f59d6e71df546 272 SMART SM00062 32 261 3.5E-41 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS07395 820b478b4ea556668a6f59d6e71df546 272 Gene3D G3DSA:3.40.190.10 111 220 3.0E-17 T 13-09-2016 THL1_RS07395 820b478b4ea556668a6f59d6e71df546 272 PANTHER PTHR18966:SF191 22 257 1.2E-34 T 13-09-2016 THL1_RS07395 820b478b4ea556668a6f59d6e71df546 272 Gene3D G3DSA:3.40.190.10 28 110 2.5E-35 T 13-09-2016 THL1_RS07395 820b478b4ea556668a6f59d6e71df546 272 Gene3D G3DSA:3.40.190.10 221 258 2.5E-35 T 13-09-2016 THL1_RS07395 820b478b4ea556668a6f59d6e71df546 272 SUPERFAMILY SSF53850 1 258 7.44E-52 T 13-09-2016 THL1_RS07395 820b478b4ea556668a6f59d6e71df546 272 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 33 257 2.1E-50 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS07395 820b478b4ea556668a6f59d6e71df546 272 PANTHER PTHR18966 22 257 1.2E-34 T 13-09-2016 THL1_RS19280 b9f3dd0bd6b1529976c9065ec304fa39 225 SUPERFAMILY SSF46894 123 223 5.67E-21 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS19280 b9f3dd0bd6b1529976c9065ec304fa39 225 SMART SM00862 147 223 3.2E-14 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS19280 b9f3dd0bd6b1529976c9065ec304fa39 225 PANTHER PTHR26402 2 223 1.3E-90 T 13-09-2016 THL1_RS19280 b9f3dd0bd6b1529976c9065ec304fa39 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 222 5.4E-15 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS19280 b9f3dd0bd6b1529976c9065ec304fa39 225 Gene3D G3DSA:3.40.50.2300 3 124 1.3E-38 T 13-09-2016 THL1_RS19280 b9f3dd0bd6b1529976c9065ec304fa39 225 Gene3D G3DSA:1.10.10.10 125 223 9.6E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19280 b9f3dd0bd6b1529976c9065ec304fa39 225 SUPERFAMILY SSF52172 4 127 1.71E-38 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS19280 b9f3dd0bd6b1529976c9065ec304fa39 225 SMART SM00448 2 113 1.5E-37 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS19280 b9f3dd0bd6b1529976c9065ec304fa39 225 Pfam PF00072 Response regulator receiver domain 5 113 1.4E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS19280 b9f3dd0bd6b1529976c9065ec304fa39 225 PANTHER PTHR26402:SF476 2 223 1.3E-90 T 13-09-2016 THL1_RS21830 da997b5d8f8c80f98befa75e491e711b 252 Gene3D G3DSA:3.10.20.30 29 75 8.8E-9 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS21830 da997b5d8f8c80f98befa75e491e711b 252 Pfam PF01927 Mut7-C RNAse domain 97 238 7.3E-45 T 13-09-2016 IPR002782 Mut7-C RNAse domain THL1_RS21830 da997b5d8f8c80f98befa75e491e711b 252 PANTHER PTHR12124:SF44 34 236 5.3E-19 T 13-09-2016 THL1_RS21830 da997b5d8f8c80f98befa75e491e711b 252 PANTHER PTHR12124 34 236 5.3E-19 T 13-09-2016 THL1_RS21830 da997b5d8f8c80f98befa75e491e711b 252 Pfam PF14451 Mut7-C ubiquitin 1 81 3.1E-37 T 13-09-2016 IPR027798 Ubiquitin Mut7-C domain THL1_RS21830 da997b5d8f8c80f98befa75e491e711b 252 SUPERFAMILY SSF54285 26 76 1.7E-6 T 13-09-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp THL1_RS09125 ca245f343fc87b60c0472a7c003c8b76 375 SUPERFAMILY SSF47819 296 370 2.8E-16 T 13-09-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 THL1_RS09125 ca245f343fc87b60c0472a7c003c8b76 375 Hamap MF_01899 Ribonuclease D [rnd]. 5 371 41.467 T 13-09-2016 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 THL1_RS09125 ca245f343fc87b60c0472a7c003c8b76 375 Pfam PF00570 HRDC domain 214 281 2.4E-15 T 13-09-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 THL1_RS09125 ca245f343fc87b60c0472a7c003c8b76 375 TIGRFAM TIGR01388 rnd: ribonuclease D 7 370 3.5E-138 T 13-09-2016 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 THL1_RS09125 ca245f343fc87b60c0472a7c003c8b76 375 PANTHER PTHR12124 3 362 1.2E-67 T 13-09-2016 THL1_RS09125 ca245f343fc87b60c0472a7c003c8b76 375 SUPERFAMILY SSF53098 4 211 1.8E-58 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS09125 ca245f343fc87b60c0472a7c003c8b76 375 SMART SM00341 211 291 4.8E-6 T 13-09-2016 IPR002121 HRDC domain GO:0003676|GO:0005622 THL1_RS09125 ca245f343fc87b60c0472a7c003c8b76 375 SMART SM00474 5 173 6.5E-37 T 13-09-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 THL1_RS09125 ca245f343fc87b60c0472a7c003c8b76 375 SUPERFAMILY SSF47819 196 301 4.86E-30 T 13-09-2016 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 THL1_RS09125 ca245f343fc87b60c0472a7c003c8b76 375 Pfam PF01612 3'-5' exonuclease 6 172 2.7E-36 T 13-09-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 THL1_RS09125 ca245f343fc87b60c0472a7c003c8b76 375 Gene3D G3DSA:3.30.420.10 6 183 3.4E-16 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS09125 ca245f343fc87b60c0472a7c003c8b76 375 PANTHER PTHR12124:SF42 3 362 1.2E-67 T 13-09-2016 THL1_RS04015 699f39463b98db757abcafff0d7c1f5f 422 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 206 293 1.3E-26 T 13-09-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 THL1_RS04015 699f39463b98db757abcafff0d7c1f5f 422 SUPERFAMILY SSF52413 317 421 6.28E-22 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS04015 699f39463b98db757abcafff0d7c1f5f 422 PIRSF PIRSF000124 4 422 5.6E-73 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS04015 699f39463b98db757abcafff0d7c1f5f 422 Gene3D G3DSA:1.20.5.100 206 235 3.8E-6 T 13-09-2016 THL1_RS04015 699f39463b98db757abcafff0d7c1f5f 422 SUPERFAMILY SSF51735 5 198 4.14E-46 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS04015 699f39463b98db757abcafff0d7c1f5f 422 PANTHER PTHR11374:SF4 1 421 2.3E-178 T 13-09-2016 THL1_RS04015 699f39463b98db757abcafff0d7c1f5f 422 PANTHER PTHR11374 1 421 2.3E-178 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS04015 699f39463b98db757abcafff0d7c1f5f 422 SUPERFAMILY SSF48179 206 299 1.7E-28 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS04015 699f39463b98db757abcafff0d7c1f5f 422 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 325 421 1.6E-17 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS04015 699f39463b98db757abcafff0d7c1f5f 422 PIRSF PIRSF500136 1 422 3.6E-151 T 13-09-2016 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 THL1_RS04015 699f39463b98db757abcafff0d7c1f5f 422 Gene3D G3DSA:3.40.50.720 238 421 1.1E-44 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS04015 699f39463b98db757abcafff0d7c1f5f 422 Gene3D G3DSA:3.40.50.720 6 201 6.8E-59 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS04015 699f39463b98db757abcafff0d7c1f5f 422 SMART SM00984 325 422 2.4E-20 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS04015 699f39463b98db757abcafff0d7c1f5f 422 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 5 418 6.3E-120 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS04015 699f39463b98db757abcafff0d7c1f5f 422 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 186 2.7E-58 T 13-09-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS01315 625df90dc2e1a38227927e6e1c96f0f0 381 Pfam PF00437 Type II/IV secretion system protein 112 269 4.6E-34 T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS01315 625df90dc2e1a38227927e6e1c96f0f0 381 Gene3D G3DSA:3.40.50.300 101 344 3.5E-62 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01315 625df90dc2e1a38227927e6e1c96f0f0 381 SUPERFAMILY SSF52540 4 336 6.51E-69 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01315 625df90dc2e1a38227927e6e1c96f0f0 381 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 344 2.8E-136 T 13-09-2016 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 THL1_RS01315 625df90dc2e1a38227927e6e1c96f0f0 381 PANTHER PTHR30486:SF3 1 375 3.0E-180 T 13-09-2016 THL1_RS01315 625df90dc2e1a38227927e6e1c96f0f0 381 PANTHER PTHR30486 1 375 3.0E-180 T 13-09-2016 THL1_RS01315 625df90dc2e1a38227927e6e1c96f0f0 381 SMART SM00382 122 247 0.0024 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS24270 29af53f891b8bebe22eba03c69ce2263 391 Gene3D G3DSA:3.90.1150.10 254 386 2.1E-32 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS24270 29af53f891b8bebe22eba03c69ce2263 391 PANTHER PTHR11751 14 386 2.8E-192 T 13-09-2016 THL1_RS24270 29af53f891b8bebe22eba03c69ce2263 391 Pfam PF00155 Aminotransferase class I and II 33 381 4.6E-50 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS24270 29af53f891b8bebe22eba03c69ce2263 391 Gene3D G3DSA:3.40.640.10 48 253 4.7E-53 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS24270 29af53f891b8bebe22eba03c69ce2263 391 SUPERFAMILY SSF53383 6 386 1.48E-92 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS24270 29af53f891b8bebe22eba03c69ce2263 391 PANTHER PTHR11751:SF401 14 386 2.8E-192 T 13-09-2016 THL1_RS24270 29af53f891b8bebe22eba03c69ce2263 391 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 231 244 - T 13-09-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 THL1_RS03785 e2443a723c6ddf350d52f8e9421f038f 309 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 142 0.0066 T 13-09-2016 THL1_RS03785 e2443a723c6ddf350d52f8e9421f038f 309 PANTHER PTHR10366:SF466 5 307 1.4E-99 T 13-09-2016 THL1_RS03785 e2443a723c6ddf350d52f8e9421f038f 309 SUPERFAMILY SSF51735 4 307 1.0E-92 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS03785 e2443a723c6ddf350d52f8e9421f038f 309 Gene3D G3DSA:3.90.25.10 178 293 8.2E-31 T 13-09-2016 THL1_RS03785 e2443a723c6ddf350d52f8e9421f038f 309 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 232 1.1E-66 T 13-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 THL1_RS03785 e2443a723c6ddf350d52f8e9421f038f 309 PANTHER PTHR10366 5 307 1.4E-99 T 13-09-2016 THL1_RS03785 e2443a723c6ddf350d52f8e9421f038f 309 Gene3D G3DSA:3.40.50.720 3 177 2.5E-59 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS00050 41cec8f99434b0867818c2bbc99b6870 254 SMART SM00563 76 190 2.0E-35 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS00050 41cec8f99434b0867818c2bbc99b6870 254 Pfam PF01553 Acyltransferase 63 187 1.3E-23 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS00050 41cec8f99434b0867818c2bbc99b6870 254 Gene3D G3DSA:3.40.1130.10 58 217 1.2E-21 T 13-09-2016 THL1_RS00050 41cec8f99434b0867818c2bbc99b6870 254 SUPERFAMILY SSF69593 10 241 1.09E-40 T 13-09-2016 THL1_RS00050 41cec8f99434b0867818c2bbc99b6870 254 PANTHER PTHR10434:SF11 1 242 2.9E-57 T 13-09-2016 THL1_RS00050 41cec8f99434b0867818c2bbc99b6870 254 PANTHER PTHR10434 1 242 2.9E-57 T 13-09-2016 THL1_RS13485 798820f2129d54a137e7286fc9448174 526 PANTHER PTHR11699 1 519 7.7E-170 T 13-09-2016 THL1_RS13485 798820f2129d54a137e7286fc9448174 526 Gene3D G3DSA:3.40.605.10 8 265 2.5E-43 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS13485 798820f2129d54a137e7286fc9448174 526 Gene3D G3DSA:3.40.309.10 267 454 1.7E-52 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS13485 798820f2129d54a137e7286fc9448174 526 Pfam PF00171 Aldehyde dehydrogenase family 35 456 1.4E-41 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS13485 798820f2129d54a137e7286fc9448174 526 PANTHER PTHR11699:SF10 1 519 7.7E-170 T 13-09-2016 THL1_RS13485 798820f2129d54a137e7286fc9448174 526 SUPERFAMILY SSF53720 23 518 1.57E-96 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS08000 87c02bbeb7286245349607b4565afa7c 75 Gene3D G3DSA:1.10.260.40 15 70 8.9E-21 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS08000 87c02bbeb7286245349607b4565afa7c 75 PANTHER PTHR36511:SF2 12 73 8.5E-18 T 13-09-2016 THL1_RS08000 87c02bbeb7286245349607b4565afa7c 75 SMART SM00530 15 69 5.8E-6 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS08000 87c02bbeb7286245349607b4565afa7c 75 PANTHER PTHR36511 12 73 8.5E-18 T 13-09-2016 THL1_RS08000 87c02bbeb7286245349607b4565afa7c 75 SUPERFAMILY SSF47413 16 66 4.86E-12 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS08000 87c02bbeb7286245349607b4565afa7c 75 Pfam PF01381 Helix-turn-helix 16 53 5.0E-8 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS05195 3dec3a8a86a4129bae68054dc3bf4905 225 Gene3D G3DSA:2.40.100.10 91 220 8.3E-45 T 13-09-2016 IPR029000 Cyclophilin-like domain THL1_RS05195 3dec3a8a86a4129bae68054dc3bf4905 225 PANTHER PTHR34698 1 225 2.2E-87 T 13-09-2016 THL1_RS05195 3dec3a8a86a4129bae68054dc3bf4905 225 Gene3D G3DSA:3.30.1360.40 3 76 5.7E-14 T 13-09-2016 IPR024946 Arginine repressor C-terminal-like domain THL1_RS05195 3dec3a8a86a4129bae68054dc3bf4905 225 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 10 210 9.3E-45 T 13-09-2016 IPR010016 KipI family THL1_RS05195 3dec3a8a86a4129bae68054dc3bf4905 225 PANTHER PTHR34698:SF2 1 225 2.2E-87 T 13-09-2016 THL1_RS05195 3dec3a8a86a4129bae68054dc3bf4905 225 Pfam PF02682 Allophanate hydrolase subunit 1 3 202 1.3E-65 T 13-09-2016 IPR003833 Carboxyltransferase domain, subdomain C and D THL1_RS05195 3dec3a8a86a4129bae68054dc3bf4905 225 SUPERFAMILY SSF160467 3 96 2.09E-15 T 13-09-2016 THL1_RS05195 3dec3a8a86a4129bae68054dc3bf4905 225 SMART SM00796 2 202 3.1E-88 T 13-09-2016 IPR003833 Carboxyltransferase domain, subdomain C and D THL1_RS05195 3dec3a8a86a4129bae68054dc3bf4905 225 SUPERFAMILY SSF50891 91 218 8.34E-42 T 13-09-2016 IPR029000 Cyclophilin-like domain THL1_RS09320 8258e3e52f1e4568fe694a1858bad4b4 521 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 124 1.3E-13 T 13-09-2016 IPR000014 PAS domain THL1_RS09320 8258e3e52f1e4568fe694a1858bad4b4 521 Pfam PF08447 PAS fold 31 113 2.8E-16 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS09320 8258e3e52f1e4568fe694a1858bad4b4 521 Gene3D G3DSA:3.30.450.20 20 112 6.3E-25 T 13-09-2016 THL1_RS09320 8258e3e52f1e4568fe694a1858bad4b4 521 SMART SM00091 8 74 3.5E-4 T 13-09-2016 IPR000014 PAS domain THL1_RS09320 8258e3e52f1e4568fe694a1858bad4b4 521 PANTHER PTHR32089 51 521 2.0E-124 T 13-09-2016 THL1_RS09320 8258e3e52f1e4568fe694a1858bad4b4 521 SUPERFAMILY SSF55785 21 114 4.36E-28 T 13-09-2016 IPR000014 PAS domain THL1_RS09320 8258e3e52f1e4568fe694a1858bad4b4 521 PANTHER PTHR32089:SF64 51 521 2.0E-124 T 13-09-2016 THL1_RS09320 8258e3e52f1e4568fe694a1858bad4b4 521 Gene3D G3DSA:1.10.287.950 273 489 2.6E-58 T 13-09-2016 THL1_RS09320 8258e3e52f1e4568fe694a1858bad4b4 521 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 322 519 3.7E-51 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS09320 8258e3e52f1e4568fe694a1858bad4b4 521 SMART SM00283 259 520 2.2E-77 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS09320 8258e3e52f1e4568fe694a1858bad4b4 521 SUPERFAMILY SSF58104 265 521 4.84E-76 T 13-09-2016 THL1_RS18655 d2d3fce009e7c755f6d95862207365f2 312 Gene3D G3DSA:3.40.366.10 198 300 1.7E-67 T 13-09-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 THL1_RS18655 d2d3fce009e7c755f6d95862207365f2 312 Gene3D G3DSA:3.40.366.10 4 123 1.7E-67 T 13-09-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 THL1_RS18655 d2d3fce009e7c755f6d95862207365f2 312 PANTHER PTHR10982 4 301 2.5E-140 T 13-09-2016 THL1_RS18655 d2d3fce009e7c755f6d95862207365f2 312 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 8 311 2.6E-34 T 13-09-2016 IPR020801 Polyketide synthase, acyl transferase domain THL1_RS18655 d2d3fce009e7c755f6d95862207365f2 312 Gene3D G3DSA:3.30.70.250 127 197 1.5E-28 T 13-09-2016 THL1_RS18655 d2d3fce009e7c755f6d95862207365f2 312 SUPERFAMILY SSF52151 199 303 2.09E-72 T 13-09-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THL1_RS18655 d2d3fce009e7c755f6d95862207365f2 312 SUPERFAMILY SSF52151 5 129 2.09E-72 T 13-09-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THL1_RS18655 d2d3fce009e7c755f6d95862207365f2 312 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 5 291 1.2E-110 T 13-09-2016 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 THL1_RS18655 d2d3fce009e7c755f6d95862207365f2 312 SUPERFAMILY SSF55048 129 198 1.12E-17 T 13-09-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 THL1_RS18655 d2d3fce009e7c755f6d95862207365f2 312 PIRSF PIRSF000446 2 312 4.0E-115 T 13-09-2016 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388|UniPathway: UPA00094 THL1_RS18655 d2d3fce009e7c755f6d95862207365f2 312 Pfam PF00698 Acyl transferase domain 7 238 3.2E-37 T 13-09-2016 IPR014043 Acyl transferase THL1_RS13045 af37f70673bbf87f381fcbdcb5e4ac1c 499 PANTHER PTHR10799 295 497 2.2E-32 T 13-09-2016 THL1_RS13045 af37f70673bbf87f381fcbdcb5e4ac1c 499 Pfam PF02743 Cache domain 38 256 9.6E-14 T 13-09-2016 IPR033479 Double Cache domain 1 THL1_RS13045 af37f70673bbf87f381fcbdcb5e4ac1c 499 Gene3D G3DSA:3.30.70.270 337 498 2.8E-51 T 13-09-2016 THL1_RS13045 af37f70673bbf87f381fcbdcb5e4ac1c 499 Gene3D G3DSA:3.30.450.20 84 163 2.1E-13 T 13-09-2016 THL1_RS13045 af37f70673bbf87f381fcbdcb5e4ac1c 499 PANTHER PTHR10799:SF750 295 497 2.2E-32 T 13-09-2016 THL1_RS13045 af37f70673bbf87f381fcbdcb5e4ac1c 499 Gene3D G3DSA:3.30.450.20 164 279 1.8E-6 T 13-09-2016 THL1_RS13045 af37f70673bbf87f381fcbdcb5e4ac1c 499 SUPERFAMILY SSF55073 340 498 9.68E-46 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS13045 af37f70673bbf87f381fcbdcb5e4ac1c 499 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 331 498 3.2E-52 T 13-09-2016 IPR000160 GGDEF domain THL1_RS13045 af37f70673bbf87f381fcbdcb5e4ac1c 499 SMART SM00267 324 499 1.6E-57 T 13-09-2016 IPR000160 GGDEF domain THL1_RS13045 af37f70673bbf87f381fcbdcb5e4ac1c 499 Pfam PF00990 Diguanylate cyclase, GGDEF domain 335 496 1.9E-47 T 13-09-2016 IPR000160 GGDEF domain THL1_RS09130 24223d2e5120389650d799303f09e85a 97 SUPERFAMILY SSF160191 2 94 5.62E-35 T 13-09-2016 THL1_RS09130 24223d2e5120389650d799303f09e85a 97 ProDom PD030374 YCGL UNCHARACTERIZED SIMILAR BACTERIA HI1446 Y2231 HYDROLASE CYTOPLASMIC YPO2080 SO2575 4 78 9.0E-33 T 13-09-2016 IPR027354 YcgL domain THL1_RS09130 24223d2e5120389650d799303f09e85a 97 PANTHER PTHR38109 4 97 5.1E-39 T 13-09-2016 THL1_RS09130 24223d2e5120389650d799303f09e85a 97 Hamap MF_01866 Protein YcgL [ycgL]. 3 90 25.491 T 13-09-2016 IPR027354 YcgL domain THL1_RS09130 24223d2e5120389650d799303f09e85a 97 Pfam PF05166 YcgL domain 5 77 1.2E-30 T 13-09-2016 IPR027354 YcgL domain THL1_RS16895 9a33886e72ed228b6b9ebf51dcd69c0e 283 SUPERFAMILY SSF52402 163 282 5.53E-22 T 13-09-2016 THL1_RS16895 9a33886e72ed228b6b9ebf51dcd69c0e 283 Gene3D G3DSA:3.40.50.620 163 282 2.8E-18 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS16895 9a33886e72ed228b6b9ebf51dcd69c0e 283 Gene3D G3DSA:3.40.50.620 4 157 7.1E-20 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS16895 9a33886e72ed228b6b9ebf51dcd69c0e 283 PRINTS PR01438 Universal stress protein signature 163 181 2.2E-10 T 13-09-2016 IPR006015 Universal stress protein A THL1_RS16895 9a33886e72ed228b6b9ebf51dcd69c0e 283 PRINTS PR01438 Universal stress protein signature 261 283 2.2E-10 T 13-09-2016 IPR006015 Universal stress protein A THL1_RS16895 9a33886e72ed228b6b9ebf51dcd69c0e 283 PRINTS PR01438 Universal stress protein signature 243 255 2.2E-10 T 13-09-2016 IPR006015 Universal stress protein A THL1_RS16895 9a33886e72ed228b6b9ebf51dcd69c0e 283 Pfam PF00582 Universal stress protein family 4 157 2.9E-16 T 13-09-2016 IPR006016 UspA GO:0006950 THL1_RS16895 9a33886e72ed228b6b9ebf51dcd69c0e 283 Pfam PF00582 Universal stress protein family 212 282 5.8E-10 T 13-09-2016 IPR006016 UspA GO:0006950 THL1_RS16895 9a33886e72ed228b6b9ebf51dcd69c0e 283 SUPERFAMILY SSF52402 3 157 3.6E-18 T 13-09-2016 THL1_RS10370 248d459ff0d9e901348be90b0fa61111 113 Pfam PF04320 Protein with unknown function (DUF469) 7 106 2.3E-31 T 13-09-2016 IPR007416 Protein of unknown function DUF469 THL1_RS10370 248d459ff0d9e901348be90b0fa61111 113 PANTHER PTHR38778:SF1 2 113 8.0E-39 T 13-09-2016 THL1_RS10370 248d459ff0d9e901348be90b0fa61111 113 PANTHER PTHR38778 2 113 8.0E-39 T 13-09-2016 THL1_RS09305 f4a133a3ae39231e5c324a4e70a49219 135 SUPERFAMILY SSF54427 2 128 7.4E-26 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS09305 f4a133a3ae39231e5c324a4e70a49219 135 Pfam PF13474 SnoaL-like domain 8 128 3.2E-14 T 13-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain THL1_RS09305 f4a133a3ae39231e5c324a4e70a49219 135 Gene3D G3DSA:3.10.450.50 3 131 8.6E-23 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS00150 6e3d7dd1cc335fca576d33c2e9dee66d 501 Pfam PF00884 Sulfatase 4 345 3.8E-56 T 13-09-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 THL1_RS00150 6e3d7dd1cc335fca576d33c2e9dee66d 501 PANTHER PTHR10342:SF207 2 467 6.6E-136 T 13-09-2016 THL1_RS00150 6e3d7dd1cc335fca576d33c2e9dee66d 501 PANTHER PTHR10342 2 467 6.6E-136 T 13-09-2016 THL1_RS00150 6e3d7dd1cc335fca576d33c2e9dee66d 501 TIGRFAM TIGR03417 chol_sulfatase: choline-sulfatase 2 499 1.3E-262 T 13-09-2016 IPR017785 Choline-sulfatase UniPathway: UPA00290 THL1_RS00150 6e3d7dd1cc335fca576d33c2e9dee66d 501 Gene3D G3DSA:3.30.1120.10 368 438 3.0E-10 T 13-09-2016 THL1_RS00150 6e3d7dd1cc335fca576d33c2e9dee66d 501 Pfam PF12411 Choline sulfatase enzyme C terminal 447 498 2.6E-26 T 13-09-2016 IPR025863 Choline sulfatase enzyme C-terminal domain UniPathway: UPA00290 THL1_RS00150 6e3d7dd1cc335fca576d33c2e9dee66d 501 ProSitePatterns PS00149 Sulfatases signature 2. 92 102 - T 13-09-2016 IPR024607 Sulfatase, conserved site THL1_RS00150 6e3d7dd1cc335fca576d33c2e9dee66d 501 Gene3D G3DSA:3.40.720.10 2 366 1.7E-98 T 13-09-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THL1_RS00150 6e3d7dd1cc335fca576d33c2e9dee66d 501 SUPERFAMILY SSF53649 2 209 2.18E-119 T 13-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THL1_RS00150 6e3d7dd1cc335fca576d33c2e9dee66d 501 SUPERFAMILY SSF53649 252 476 2.18E-119 T 13-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THL1_RS18585 b6958c8b19040a17595f4e31bb3ece22 1035 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 10 691 1.7E-166 T 13-09-2016 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 THL1_RS18585 b6958c8b19040a17595f4e31bb3ece22 1035 SUPERFAMILY SSF52540 450 482 9.56E-5 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18585 b6958c8b19040a17595f4e31bb3ece22 1035 SUPERFAMILY SSF52540 587 675 9.56E-5 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18585 b6958c8b19040a17595f4e31bb3ece22 1035 SUPERFAMILY SSF52540 523 551 9.56E-5 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18585 b6958c8b19040a17595f4e31bb3ece22 1035 SUPERFAMILY SSF52540 389 423 9.56E-5 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18585 b6958c8b19040a17595f4e31bb3ece22 1035 PANTHER PTHR30195 80 922 6.5E-109 T 13-09-2016 THL1_RS18585 b6958c8b19040a17595f4e31bb3ece22 1035 PANTHER PTHR30195:SF15 80 922 6.5E-109 T 13-09-2016 THL1_RS18585 b6958c8b19040a17595f4e31bb3ece22 1035 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 8 200 5.4E-36 T 13-09-2016 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 THL1_RS18585 b6958c8b19040a17595f4e31bb3ece22 1035 Pfam PF04851 Type III restriction enzyme, res subunit 258 423 4.1E-16 T 13-09-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THL1_RS18585 b6958c8b19040a17595f4e31bb3ece22 1035 SUPERFAMILY SSF52540 219 427 1.58E-23 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18585 b6958c8b19040a17595f4e31bb3ece22 1035 Gene3D G3DSA:3.40.50.300 256 439 6.5E-20 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18585 b6958c8b19040a17595f4e31bb3ece22 1035 SMART SM00487 251 460 5.1E-10 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS23215 8d652c16d9c6437ac9ee876f3e655bc2 385 PANTHER PTHR21248:SF5 1 384 1.8E-102 T 13-09-2016 THL1_RS23215 8d652c16d9c6437ac9ee876f3e655bc2 385 SUPERFAMILY SSF56024 3 176 1.51E-40 T 13-09-2016 THL1_RS23215 8d652c16d9c6437ac9ee876f3e655bc2 385 Gene3D G3DSA:3.30.870.10 210 354 4.1E-33 T 13-09-2016 THL1_RS23215 8d652c16d9c6437ac9ee876f3e655bc2 385 SMART SM00155 291 317 11.0 T 13-09-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 THL1_RS23215 8d652c16d9c6437ac9ee876f3e655bc2 385 SMART SM00155 109 136 0.38 T 13-09-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 THL1_RS23215 8d652c16d9c6437ac9ee876f3e655bc2 385 Gene3D G3DSA:3.30.870.10 6 172 5.5E-39 T 13-09-2016 THL1_RS23215 8d652c16d9c6437ac9ee876f3e655bc2 385 PANTHER PTHR21248 1 384 1.8E-102 T 13-09-2016 THL1_RS23215 8d652c16d9c6437ac9ee876f3e655bc2 385 SUPERFAMILY SSF56024 208 364 4.93E-36 T 13-09-2016 THL1_RS23215 8d652c16d9c6437ac9ee876f3e655bc2 385 Pfam PF13091 PLD-like domain 28 169 3.6E-13 T 13-09-2016 IPR025202 Phospholipase D-like domain THL1_RS23215 8d652c16d9c6437ac9ee876f3e655bc2 385 Pfam PF13091 PLD-like domain 219 343 3.2E-25 T 13-09-2016 IPR025202 Phospholipase D-like domain THL1_RS07220 0130ffb4a83309c77c57aedd5e1b0ade 601 SUPERFAMILY SSF51735 407 543 8.09E-30 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07220 0130ffb4a83309c77c57aedd5e1b0ade 601 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 15 288 1.1E-85 T 13-09-2016 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 THL1_RS07220 0130ffb4a83309c77c57aedd5e1b0ade 601 Pfam PF00999 Sodium/hydrogen exchanger family 12 378 8.7E-67 T 13-09-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 THL1_RS07220 0130ffb4a83309c77c57aedd5e1b0ade 601 PANTHER PTHR16254:SF6 1 563 6.4E-232 T 13-09-2016 THL1_RS07220 0130ffb4a83309c77c57aedd5e1b0ade 601 PANTHER PTHR16254 1 563 6.4E-232 T 13-09-2016 THL1_RS07220 0130ffb4a83309c77c57aedd5e1b0ade 601 Pfam PF02254 TrkA-N domain 409 519 2.7E-23 T 13-09-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 THL1_RS07220 0130ffb4a83309c77c57aedd5e1b0ade 601 Gene3D G3DSA:3.40.50.720 402 537 1.5E-33 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 83 96 - T 13-09-2016 IPR020583 Inositol monophosphatase, metal-binding site THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 PANTHER PTHR20854 1 262 7.2E-98 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 Gene3D G3DSA:3.30.540.10 2 153 8.3E-51 T 13-09-2016 THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 215 229 - T 13-09-2016 IPR020550 Inositol monophosphatase, conserved site GO:0046854 THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 2.8E-21 T 13-09-2016 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 PRINTS PR01959 SuhB family inositol monophosphatase signature 160 186 2.8E-21 T 13-09-2016 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 PRINTS PR01959 SuhB family inositol monophosphatase signature 106 125 2.8E-21 T 13-09-2016 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 PRINTS PR01959 SuhB family inositol monophosphatase signature 202 214 2.8E-21 T 13-09-2016 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 PANTHER PTHR20854:SF4 1 262 7.2E-98 T 13-09-2016 THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 132 155 5.4E-62 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 5.4E-62 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 212 236 5.4E-62 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 83 99 5.4E-62 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 5.4E-62 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 PRINTS PR00377 Inositol monophosphatase superfamily signature 181 202 5.4E-62 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 Gene3D G3DSA:3.40.190.80 154 265 2.3E-41 T 13-09-2016 THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 SUPERFAMILY SSF56655 1 265 8.51E-85 T 13-09-2016 THL1_RS05910 557d6c9600f7d24fcf977c88adfdc04d 271 Pfam PF00459 Inositol monophosphatase family 1 258 3.8E-66 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS04090 23ff909380e929973a3ab96d2e6e7cae 464 PIRSF PIRSF018788 2 461 3.4E-240 T 13-09-2016 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7|UniPathway: UPA00560 THL1_RS04090 23ff909380e929973a3ab96d2e6e7cae 464 Gene3D G3DSA:3.20.20.70 143 443 4.6E-164 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS04090 23ff909380e929973a3ab96d2e6e7cae 464 PANTHER PTHR39329 2 462 9.7E-303 T 13-09-2016 THL1_RS04090 23ff909380e929973a3ab96d2e6e7cae 464 PANTHER PTHR39329:SF1 2 462 9.7E-303 T 13-09-2016 THL1_RS04090 23ff909380e929973a3ab96d2e6e7cae 464 Gene3D G3DSA:1.10.220.70 56 142 5.1E-40 T 13-09-2016 THL1_RS04090 23ff909380e929973a3ab96d2e6e7cae 464 Gene3D G3DSA:2.30.170.30 3 55 1.1E-25 T 13-09-2016 THL1_RS04090 23ff909380e929973a3ab96d2e6e7cae 464 Pfam PF06751 Ethanolamine ammonia lyase large subunit (EutB) 13 441 2.0E-220 T 13-09-2016 IPR010628 Ethanolamine ammonia lyase large subunit GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7|UniPathway: UPA00560 THL1_RS28190 fa54047be86b2acdc5cee021a4cc583d 471 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 320 2.3E-74 T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS28190 fa54047be86b2acdc5cee021a4cc583d 471 Gene3D G3DSA:3.40.50.20 2 128 2.2E-50 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS28190 fa54047be86b2acdc5cee021a4cc583d 471 SUPERFAMILY SSF51246 329 445 1.99E-42 T 13-09-2016 IPR011054 Rudiment single hybrid motif THL1_RS28190 fa54047be86b2acdc5cee021a4cc583d 471 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 284 291 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS28190 fa54047be86b2acdc5cee021a4cc583d 471 SUPERFAMILY SSF52440 1 112 1.37E-45 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS28190 fa54047be86b2acdc5cee021a4cc583d 471 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 1.3E-42 T 13-09-2016 IPR005481 Biotin carboxylase-like, N-terminal domain THL1_RS28190 fa54047be86b2acdc5cee021a4cc583d 471 SMART SM00878 334 440 1.1E-60 T 13-09-2016 IPR005482 Biotin carboxylase, C-terminal THL1_RS28190 fa54047be86b2acdc5cee021a4cc583d 471 SUPERFAMILY SSF56059 82 346 2.12E-67 T 13-09-2016 THL1_RS28190 fa54047be86b2acdc5cee021a4cc583d 471 Pfam PF02785 Biotin carboxylase C-terminal domain 334 440 1.6E-40 T 13-09-2016 IPR005482 Biotin carboxylase, C-terminal THL1_RS28190 fa54047be86b2acdc5cee021a4cc583d 471 PANTHER PTHR18866 1 468 0.0 T 13-09-2016 THL1_RS28190 fa54047be86b2acdc5cee021a4cc583d 471 PANTHER PTHR18866:SF111 1 468 0.0 T 13-09-2016 THL1_RS28190 fa54047be86b2acdc5cee021a4cc583d 471 Gene3D G3DSA:3.30.1490.20 129 200 1.9E-27 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS28190 fa54047be86b2acdc5cee021a4cc583d 471 Gene3D G3DSA:3.30.470.20 203 445 3.9E-94 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS28190 fa54047be86b2acdc5cee021a4cc583d 471 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS08115 6c31f40e2443153d3eb1944967320af2 276 Gene3D G3DSA:3.40.50.620 27 273 2.7E-66 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS08115 6c31f40e2443153d3eb1944967320af2 276 SUPERFAMILY SSF52402 28 275 1.13E-72 T 13-09-2016 THL1_RS08115 6c31f40e2443153d3eb1944967320af2 276 TIGRFAM TIGR00552 nadE: NAD+ synthetase 30 273 7.9E-65 T 13-09-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 THL1_RS08115 6c31f40e2443153d3eb1944967320af2 276 PANTHER PTHR23090 6 276 1.4E-126 T 13-09-2016 THL1_RS08115 6c31f40e2443153d3eb1944967320af2 276 PANTHER PTHR23090:SF7 6 276 1.4E-126 T 13-09-2016 THL1_RS08115 6c31f40e2443153d3eb1944967320af2 276 Pfam PF02540 NAD synthase 29 273 2.4E-62 T 13-09-2016 IPR022310 NAD/GMP synthase THL1_RS08115 6c31f40e2443153d3eb1944967320af2 276 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 20 276 31.361 T 13-09-2016 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 THL1_RS11470 faaff2b94760f7a7881a2fd94507d373 124 PANTHER PTHR10245 3 64 1.2E-13 T 13-09-2016 THL1_RS11470 faaff2b94760f7a7881a2fd94507d373 124 SMART SM00530 7 63 4.2E-12 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS11470 faaff2b94760f7a7881a2fd94507d373 124 Pfam PF01381 Helix-turn-helix 9 63 1.7E-14 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS11470 faaff2b94760f7a7881a2fd94507d373 124 Gene3D G3DSA:1.10.260.40 3 70 5.2E-21 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS11470 faaff2b94760f7a7881a2fd94507d373 124 SUPERFAMILY SSF47413 1 66 1.39E-15 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS21380 ce90d8879e1b9c3590ae90d8de8ee8c8 324 PANTHER PTHR30349:SF29 1 285 2.9E-163 T 13-09-2016 THL1_RS21380 ce90d8879e1b9c3590ae90d8de8ee8c8 324 SUPERFAMILY SSF53850 58 229 6.73E-8 T 13-09-2016 THL1_RS21380 ce90d8879e1b9c3590ae90d8de8ee8c8 324 PANTHER PTHR30349 1 285 2.9E-163 T 13-09-2016 THL1_RS21380 ce90d8879e1b9c3590ae90d8de8ee8c8 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 69 321 1.4E-20 T 13-09-2016 IPR005064 Bordetella uptake gene GO:0030288 THL1_RS21380 ce90d8879e1b9c3590ae90d8de8ee8c8 324 PIRSF PIRSF017082 4 324 3.1E-75 T 13-09-2016 IPR005064 Bordetella uptake gene GO:0030288 THL1_RS24450 19224394b1e3187bf7752fb0b026a5a9 104 PANTHER PTHR40065:SF1 1 101 7.1E-28 T 13-09-2016 THL1_RS24450 19224394b1e3187bf7752fb0b026a5a9 104 SMART SM01103 3 86 1.5E-37 T 13-09-2016 IPR001890 RNA-binding, CRM domain GO:0003723 THL1_RS24450 19224394b1e3187bf7752fb0b026a5a9 104 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 12 93 2.0E-33 T 13-09-2016 IPR001890 RNA-binding, CRM domain GO:0003723 THL1_RS24450 19224394b1e3187bf7752fb0b026a5a9 104 SUPERFAMILY SSF75471 1 96 2.88E-27 T 13-09-2016 IPR001890 RNA-binding, CRM domain GO:0003723 THL1_RS24450 19224394b1e3187bf7752fb0b026a5a9 104 Gene3D G3DSA:3.30.110.60 2 94 1.2E-27 T 13-09-2016 IPR001890 RNA-binding, CRM domain GO:0003723 THL1_RS24450 19224394b1e3187bf7752fb0b026a5a9 104 Pfam PF01985 CRS1 / YhbY (CRM) domain 3 86 2.3E-18 T 13-09-2016 IPR001890 RNA-binding, CRM domain GO:0003723 THL1_RS24450 19224394b1e3187bf7752fb0b026a5a9 104 PANTHER PTHR40065 1 101 7.1E-28 T 13-09-2016 THL1_RS25485 37c924c0da112ad2c96d1c99b942480a 331 SUPERFAMILY SSF51395 13 322 3.48E-94 T 13-09-2016 THL1_RS25485 37c924c0da112ad2c96d1c99b942480a 331 PIRSF PIRSF006621 4 329 6.7E-107 T 13-09-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 THL1_RS25485 37c924c0da112ad2c96d1c99b942480a 331 Gene3D G3DSA:3.20.20.70 11 247 3.4E-85 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS25485 37c924c0da112ad2c96d1c99b942480a 331 PANTHER PTHR11082 6 331 1.5E-145 T 13-09-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 THL1_RS25485 37c924c0da112ad2c96d1c99b942480a 331 Pfam PF01207 Dihydrouridine synthase (Dus) 16 320 1.0E-109 T 13-09-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 THL1_RS25485 37c924c0da112ad2c96d1c99b942480a 331 PANTHER PTHR11082:SF25 6 331 1.5E-145 T 13-09-2016 THL1_RS25485 37c924c0da112ad2c96d1c99b942480a 331 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 4 324 51.023 T 13-09-2016 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 THL1_RS25485 37c924c0da112ad2c96d1c99b942480a 331 Gene3D G3DSA:1.10.1200.80 257 324 1.1E-22 T 13-09-2016 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 THL1_RS25485 37c924c0da112ad2c96d1c99b942480a 331 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 6 321 4.8E-128 T 13-09-2016 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 THL1_RS25485 37c924c0da112ad2c96d1c99b942480a 331 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 97 115 - T 13-09-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 Gene3D G3DSA:1.20.200.10 113 380 5.3E-108 T 13-09-2016 THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 PRINTS PR00149 Fumarate lyase superfamily signature 281 297 5.1E-31 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 PRINTS PR00149 Fumarate lyase superfamily signature 237 264 5.1E-31 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 PRINTS PR00149 Fumarate lyase superfamily signature 108 126 5.1E-31 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 PRINTS PR00149 Fumarate lyase superfamily signature 153 171 5.1E-31 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 Pfam PF00206 Lyase 12 306 1.7E-78 T 13-09-2016 IPR022761 Fumarate lyase, N-terminal THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 SUPERFAMILY SSF48557 10 460 1.57E-156 T 13-09-2016 IPR008948 L-Aspartase-like GO:0003824 THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 ProSitePatterns PS00163 Fumarate lyases signature. 281 290 - T 13-09-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 PANTHER PTHR11444 7 461 1.4E-238 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 TIGRFAM TIGR00838 argH: argininosuccinate lyase 10 460 6.1E-194 T 13-09-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 PANTHER PTHR11444:SF3 7 461 1.4E-238 T 13-09-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 PRINTS PR00145 Argininosuccinate lyase family signature 107 129 1.1E-69 T 13-09-2016 THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 PRINTS PR00145 Argininosuccinate lyase family signature 316 335 1.1E-69 T 13-09-2016 THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 PRINTS PR00145 Argininosuccinate lyase family signature 148 168 1.1E-69 T 13-09-2016 THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 PRINTS PR00145 Argininosuccinate lyase family signature 237 261 1.1E-69 T 13-09-2016 THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 PRINTS PR00145 Argininosuccinate lyase family signature 281 297 1.1E-69 T 13-09-2016 THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 PRINTS PR00145 Argininosuccinate lyase family signature 199 215 1.1E-69 T 13-09-2016 THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 Gene3D G3DSA:1.10.40.30 381 438 6.8E-31 T 13-09-2016 THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 Pfam PF14698 Argininosuccinate lyase C-terminal 369 437 7.4E-25 T 13-09-2016 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 Hamap MF_00006 Argininosuccinate lyase [argH]. 8 459 43.948 T 13-09-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS27460 450308dd049f08954928bbf634cb7c95 464 Gene3D G3DSA:1.10.275.10 8 112 7.0E-42 T 13-09-2016 IPR024083 Fumarase/histidase, N-terminal THL1_RS20435 a15c8108fa6bd24ddab3796537c13caf 246 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 153 244 2.0E-27 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS20435 a15c8108fa6bd24ddab3796537c13caf 246 Pfam PF08447 PAS fold 53 143 2.3E-22 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS20435 a15c8108fa6bd24ddab3796537c13caf 246 SUPERFAMILY SSF55785 50 152 9.95E-16 T 13-09-2016 IPR000014 PAS domain THL1_RS20435 a15c8108fa6bd24ddab3796537c13caf 246 Gene3D G3DSA:1.10.287.950 164 240 2.6E-30 T 13-09-2016 THL1_RS20435 a15c8108fa6bd24ddab3796537c13caf 246 Gene3D G3DSA:3.30.450.20 17 147 1.7E-22 T 13-09-2016 THL1_RS20435 a15c8108fa6bd24ddab3796537c13caf 246 PANTHER PTHR32089 167 235 1.9E-28 T 13-09-2016 THL1_RS20435 a15c8108fa6bd24ddab3796537c13caf 246 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 180 207 1.6E-16 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS20435 a15c8108fa6bd24ddab3796537c13caf 246 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 209 238 1.6E-16 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS20435 a15c8108fa6bd24ddab3796537c13caf 246 SUPERFAMILY SSF58104 165 241 3.66E-34 T 13-09-2016 THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 SUPERFAMILY SSF47384 191 272 5.69E-22 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 Pfam PF11808 Domain of unknown function (DUF3329) 5 90 4.3E-27 T 13-09-2016 IPR021766 Protein of unknown function DUF3329 GO:0004673 THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 SMART SM00091 98 165 4.6E-4 T 13-09-2016 IPR000014 PAS domain THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 Pfam PF00512 His Kinase A (phospho-acceptor) domain 205 271 2.8E-19 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 94 425 2.4E-137 T 13-09-2016 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 319 428 2.3E-22 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 SUPERFAMILY SSF55785 109 204 9.95E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 PANTHER PTHR24423:SF554 41 434 1.4E-163 T 13-09-2016 THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 SMART SM00388 205 272 3.3E-21 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 368 6.5E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 426 6.5E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 407 6.5E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 382 6.5E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 Gene3D G3DSA:1.10.287.130 197 257 3.5E-21 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 Gene3D G3DSA:3.30.565.10 258 428 2.2E-40 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 PANTHER PTHR24423 41 434 1.4E-163 T 13-09-2016 THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 SUPERFAMILY SSF55874 261 427 7.47E-39 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 SMART SM00387 317 429 1.5E-33 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 Gene3D G3DSA:3.30.450.20 105 196 1.4E-9 T 13-09-2016 THL1_RS27995 369d3c1004aaa419214a62dc54e57498 434 Pfam PF00989 PAS fold 100 154 1.5E-6 T 13-09-2016 IPR013767 PAS fold GO:0006355 THL1_RS19140 8d1147f5e5fbc8bb45ceff2ba2cdf6a7 575 PANTHER PTHR22642 4 571 4.8E-207 T 13-09-2016 THL1_RS19140 8d1147f5e5fbc8bb45ceff2ba2cdf6a7 575 Gene3D G3DSA:2.30.40.10 15 92 8.8E-23 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS19140 8d1147f5e5fbc8bb45ceff2ba2cdf6a7 575 PANTHER PTHR22642:SF9 4 571 4.8E-207 T 13-09-2016 THL1_RS19140 8d1147f5e5fbc8bb45ceff2ba2cdf6a7 575 SUPERFAMILY SSF51338 20 83 2.7E-24 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS19140 8d1147f5e5fbc8bb45ceff2ba2cdf6a7 575 SUPERFAMILY SSF51338 530 572 2.7E-24 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS19140 8d1147f5e5fbc8bb45ceff2ba2cdf6a7 575 Pfam PF07969 Amidohydrolase family 71 571 5.8E-80 T 13-09-2016 IPR013108 Amidohydrolase 3 THL1_RS19140 8d1147f5e5fbc8bb45ceff2ba2cdf6a7 575 SUPERFAMILY SSF51556 226 531 6.45E-37 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS19140 8d1147f5e5fbc8bb45ceff2ba2cdf6a7 575 SUPERFAMILY SSF51556 82 146 6.45E-37 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS19140 8d1147f5e5fbc8bb45ceff2ba2cdf6a7 575 Gene3D G3DSA:2.30.40.10 517 572 4.7E-9 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS19140 8d1147f5e5fbc8bb45ceff2ba2cdf6a7 575 Gene3D G3DSA:3.20.20.140 228 516 1.1E-25 T 13-09-2016 THL1_RS19140 8d1147f5e5fbc8bb45ceff2ba2cdf6a7 575 Gene3D G3DSA:3.20.20.140 93 105 1.1E-25 T 13-09-2016 THL1_RS00420 2cc6d1bfa2cd737ddb822fd26f8bba25 448 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 360 369 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS00420 2cc6d1bfa2cd737ddb822fd26f8bba25 448 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 171 184 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS00420 2cc6d1bfa2cd737ddb822fd26f8bba25 448 PANTHER PTHR32071:SF18 1 448 5.8E-189 T 13-09-2016 THL1_RS00420 2cc6d1bfa2cd737ddb822fd26f8bba25 448 PANTHER PTHR32071 1 448 5.8E-189 T 13-09-2016 THL1_RS00420 2cc6d1bfa2cd737ddb822fd26f8bba25 448 SUPERFAMILY SSF52172 9 192 2.42E-40 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS00420 2cc6d1bfa2cd737ddb822fd26f8bba25 448 SMART SM00448 9 120 1.5E-34 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS00420 2cc6d1bfa2cd737ddb822fd26f8bba25 448 SUPERFAMILY SSF52540 149 388 2.3E-69 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00420 2cc6d1bfa2cd737ddb822fd26f8bba25 448 Gene3D G3DSA:3.40.50.2300 10 139 1.2E-33 T 13-09-2016 THL1_RS00420 2cc6d1bfa2cd737ddb822fd26f8bba25 448 Gene3D G3DSA:3.40.50.300 149 319 6.7E-50 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00420 2cc6d1bfa2cd737ddb822fd26f8bba25 448 Gene3D G3DSA:1.10.8.60 320 390 2.7E-26 T 13-09-2016 THL1_RS00420 2cc6d1bfa2cd737ddb822fd26f8bba25 448 SMART SM00382 167 310 4.5E-11 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS00420 2cc6d1bfa2cd737ddb822fd26f8bba25 448 Gene3D G3DSA:1.10.10.60 399 448 8.9E-7 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS00420 2cc6d1bfa2cd737ddb822fd26f8bba25 448 Pfam PF00158 Sigma-54 interaction domain 149 313 1.7E-62 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS00420 2cc6d1bfa2cd737ddb822fd26f8bba25 448 Pfam PF02954 Bacterial regulatory protein, Fis family 406 444 4.1E-6 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS00420 2cc6d1bfa2cd737ddb822fd26f8bba25 448 Pfam PF00072 Response regulator receiver domain 11 119 5.6E-29 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS00420 2cc6d1bfa2cd737ddb822fd26f8bba25 448 SUPERFAMILY SSF46689 360 448 9.86E-7 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS00420 2cc6d1bfa2cd737ddb822fd26f8bba25 448 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 233 248 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS07345 e12717290f3944a6892540f5686d872b 288 SUPERFAMILY SSF53328 92 287 4.19E-60 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS07345 e12717290f3944a6892540f5686d872b 288 PIRSF PIRSF036480 5 288 3.8E-109 T 13-09-2016 THL1_RS07345 e12717290f3944a6892540f5686d872b 288 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 9 287 9.9E-101 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS07345 e12717290f3944a6892540f5686d872b 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 10 36 1.1E-49 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS07345 e12717290f3944a6892540f5686d872b 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 239 261 1.1E-49 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS07345 e12717290f3944a6892540f5686d872b 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 93 115 1.1E-49 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS07345 e12717290f3944a6892540f5686d872b 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 261 286 1.1E-49 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS07345 e12717290f3944a6892540f5686d872b 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 42 54 1.1E-49 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS07345 e12717290f3944a6892540f5686d872b 288 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 115 142 1.1E-49 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS07345 e12717290f3944a6892540f5686d872b 288 Gene3D G3DSA:3.40.50.170 92 283 1.1E-53 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS07345 e12717290f3944a6892540f5686d872b 288 PANTHER PTHR10520 6 281 3.4E-143 T 13-09-2016 THL1_RS07345 e12717290f3944a6892540f5686d872b 288 PANTHER PTHR10520:SF7 6 281 3.4E-143 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS07345 e12717290f3944a6892540f5686d872b 288 SUPERFAMILY SSF55021 7 88 1.42E-15 T 13-09-2016 THL1_RS07345 e12717290f3944a6892540f5686d872b 288 Gene3D G3DSA:3.30.70.260 4 87 1.2E-21 T 13-09-2016 THL1_RS07345 e12717290f3944a6892540f5686d872b 288 Pfam PF00551 Formyl transferase 92 269 4.0E-35 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS07345 e12717290f3944a6892540f5686d872b 288 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 5 287 46.829 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 Gene3D G3DSA:1.10.3210.10 431 620 8.6E-24 T 13-09-2016 IPR006674 HD domain THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 SUPERFAMILY SSF81593 199 313 1.8E-10 T 13-09-2016 THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 SUPERFAMILY SSF81301 8 177 5.89E-26 T 13-09-2016 THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 36 885 0.0 T 13-09-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 SUPERFAMILY SSF55021 814 877 2.52E-10 T 13-09-2016 THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 SUPERFAMILY SSF55021 703 769 3.57E-5 T 13-09-2016 THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 PIRSF PIRSF006288 12 892 0.0 T 13-09-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 PANTHER PTHR13734:SF45 104 698 1.3E-135 T 13-09-2016 THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 SUPERFAMILY SSF109604 426 590 1.38E-14 T 13-09-2016 THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 Gene3D G3DSA:3.30.70.260 815 876 4.0E-10 T 13-09-2016 THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 Gene3D G3DSA:3.30.460.10 69 172 5.8E-13 T 13-09-2016 THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 Pfam PF08335 GlnD PII-uridylyltransferase 184 321 1.5E-36 T 13-09-2016 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 Pfam PF01909 Nucleotidyltransferase domain 73 109 4.2E-6 T 13-09-2016 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 Pfam PF01842 ACT domain 815 865 1.0E-6 T 13-09-2016 IPR002912 ACT domain GO:0008152|GO:0016597 THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 SMART SM00471 457 604 7.6E-10 T 13-09-2016 IPR003607 HD/PDEase domain THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 897 343.248 T 13-09-2016 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 PANTHER PTHR13734 104 698 1.3E-135 T 13-09-2016 THL1_RS22650 25af3c0c0baf8aee68d9e512d5f02a21 900 Pfam PF01966 HD domain 482 574 3.2E-11 T 13-09-2016 IPR006674 HD domain THL1_RS13490 b85ad1c138b503462b52015f48b6d258 344 Gene3D G3DSA:1.10.10.60 238 290 2.8E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13490 b85ad1c138b503462b52015f48b6d258 344 PANTHER PTHR11019 34 53 1.5E-40 T 13-09-2016 THL1_RS13490 b85ad1c138b503462b52015f48b6d258 344 SUPERFAMILY SSF46689 290 340 1.88E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13490 b85ad1c138b503462b52015f48b6d258 344 Gene3D G3DSA:3.40.50.880 31 222 8.0E-28 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS13490 b85ad1c138b503462b52015f48b6d258 344 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 291 333 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS13490 b85ad1c138b503462b52015f48b6d258 344 Pfam PF01965 DJ-1/PfpI family 30 199 6.7E-11 T 13-09-2016 IPR002818 DJ-1/PfpI THL1_RS13490 b85ad1c138b503462b52015f48b6d258 344 PANTHER PTHR11019:SF90 78 344 1.5E-40 T 13-09-2016 THL1_RS13490 b85ad1c138b503462b52015f48b6d258 344 Gene3D G3DSA:1.10.10.60 291 341 1.6E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13490 b85ad1c138b503462b52015f48b6d258 344 PANTHER PTHR11019 78 344 1.5E-40 T 13-09-2016 THL1_RS13490 b85ad1c138b503462b52015f48b6d258 344 SUPERFAMILY SSF46689 238 288 2.78E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13490 b85ad1c138b503462b52015f48b6d258 344 SMART SM00342 254 337 7.1E-27 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS13490 b85ad1c138b503462b52015f48b6d258 344 SUPERFAMILY SSF52317 30 216 8.7E-32 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS13490 b85ad1c138b503462b52015f48b6d258 344 Pfam PF12833 Helix-turn-helix domain 260 339 9.4E-23 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS13490 b85ad1c138b503462b52015f48b6d258 344 PANTHER PTHR11019:SF90 34 53 1.5E-40 T 13-09-2016 THL1_RS04745 8cd51422f4b6ff04dd425c28611764c1 417 Gene3D G3DSA:3.40.640.10 37 284 2.8E-108 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS04745 8cd51422f4b6ff04dd425c28611764c1 417 Gene3D G3DSA:3.90.1150.10 285 416 6.2E-55 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS04745 8cd51422f4b6ff04dd425c28611764c1 417 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 416 53.184 T 13-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 THL1_RS04745 8cd51422f4b6ff04dd425c28611764c1 417 PANTHER PTHR11680 8 416 0.0 T 13-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 THL1_RS04745 8cd51422f4b6ff04dd425c28611764c1 417 PANTHER PTHR11680:SF9 8 416 0.0 T 13-09-2016 THL1_RS04745 8cd51422f4b6ff04dd425c28611764c1 417 Pfam PF00464 Serine hydroxymethyltransferase 9 385 7.3E-183 T 13-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 THL1_RS04745 8cd51422f4b6ff04dd425c28611764c1 417 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 13-09-2016 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 THL1_RS04745 8cd51422f4b6ff04dd425c28611764c1 417 PIRSF PIRSF000412 2 417 2.1E-167 T 13-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 THL1_RS04745 8cd51422f4b6ff04dd425c28611764c1 417 SUPERFAMILY SSF53383 6 416 1.18E-180 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS26040 7461a3ba1fc99f91bc2428de1a267ac1 110 SUPERFAMILY SSF103481 5 106 2.35E-19 T 13-09-2016 THL1_RS26040 7461a3ba1fc99f91bc2428de1a267ac1 110 PANTHER PTHR30561:SF1 1 110 1.2E-51 T 13-09-2016 THL1_RS26040 7461a3ba1fc99f91bc2428de1a267ac1 110 Pfam PF00893 Small Multidrug Resistance protein 3 94 4.6E-27 T 13-09-2016 IPR000390 Small multidrug resistance protein family GO:0016021 THL1_RS26040 7461a3ba1fc99f91bc2428de1a267ac1 110 PANTHER PTHR30561 1 110 1.2E-51 T 13-09-2016 THL1_RS01750 74867d73dc7d7df5bfea3b95638999c5 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 263 4.6E-27 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01750 74867d73dc7d7df5bfea3b95638999c5 295 PANTHER PTHR30177:SF2 3 282 7.6E-125 T 13-09-2016 THL1_RS01750 74867d73dc7d7df5bfea3b95638999c5 295 SUPERFAMILY SSF161098 83 267 8.76E-43 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01750 74867d73dc7d7df5bfea3b95638999c5 295 Gene3D G3DSA:1.10.3720.10 40 263 1.6E-42 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01750 74867d73dc7d7df5bfea3b95638999c5 295 PANTHER PTHR30177 3 282 7.6E-125 T 13-09-2016 THL1_RS21345 0de140b63277637ef0861e354d614729 84 Pfam PF03937 Flavinator of succinate dehydrogenase 8 77 1.5E-24 T 13-09-2016 IPR005631 Flavinator of succinate dehydrogenase THL1_RS21345 0de140b63277637ef0861e354d614729 84 PANTHER PTHR39585:SF1 2 83 5.8E-32 T 13-09-2016 THL1_RS21345 0de140b63277637ef0861e354d614729 84 Gene3D G3DSA:1.10.150.250 3 83 4.6E-28 T 13-09-2016 IPR005631 Flavinator of succinate dehydrogenase THL1_RS21345 0de140b63277637ef0861e354d614729 84 PANTHER PTHR39585 2 83 5.8E-32 T 13-09-2016 THL1_RS21345 0de140b63277637ef0861e354d614729 84 SUPERFAMILY SSF109910 3 79 5.62E-24 T 13-09-2016 IPR005631 Flavinator of succinate dehydrogenase THL1_RS12455 b3c036534e364cc4b8069b9b403a0c4a 118 PANTHER PTHR38780 1 118 2.0E-49 T 13-09-2016 THL1_RS12455 b3c036534e364cc4b8069b9b403a0c4a 118 Gene3D G3DSA:3.40.1260.10 1 117 2.5E-41 T 13-09-2016 IPR027396 DsrEFH-like THL1_RS12455 b3c036534e364cc4b8069b9b403a0c4a 118 Pfam PF02635 DsrE/DsrF-like family 2 117 1.4E-19 T 13-09-2016 IPR003787 Sulphur relay, DsrE/F-like protein THL1_RS12455 b3c036534e364cc4b8069b9b403a0c4a 118 TIGRFAM TIGR03010 sulf_tusC_dsrF: sulfur relay protein TusC/DsrF 4 117 3.7E-39 T 13-09-2016 IPR017462 Sulphur relay, TusC/DsrF THL1_RS12455 b3c036534e364cc4b8069b9b403a0c4a 118 SUPERFAMILY SSF75169 1 117 4.45E-35 T 13-09-2016 IPR027396 DsrEFH-like THL1_RS12455 b3c036534e364cc4b8069b9b403a0c4a 118 PANTHER PTHR38780:SF1 1 118 2.0E-49 T 13-09-2016 THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 SUPERFAMILY SSF55326 625 814 1.78E-66 T 13-09-2016 THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1042 1297 3.7E-107 T 13-09-2016 THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 1 1298 21.41 T 13-09-2016 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 PANTHER PTHR10099:SF5 1 1298 0.0 T 13-09-2016 THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 PANTHER PTHR10099 1 1298 0.0 T 13-09-2016 THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 SUPERFAMILY SSF56042 823 1036 2.09E-53 T 13-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 SUPERFAMILY SSF82697 1 150 4.6E-48 T 13-09-2016 THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 Gene3D G3DSA:3.40.50.880 1043 1266 1.4E-10 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 SUPERFAMILY SSF55326 219 426 8.72E-64 T 13-09-2016 THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 3 1297 0.0 T 13-09-2016 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 Pfam PF02769 AIR synthase related protein, C-terminal domain 836 966 9.7E-14 T 13-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 Pfam PF02769 AIR synthase related protein, C-terminal domain 431 587 4.7E-31 T 13-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 SMART SM01211 1042 1297 2.3E-154 T 13-09-2016 THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 SUPERFAMILY SSF109736 153 218 3.66E-22 T 13-09-2016 THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 Gene3D G3DSA:3.30.1330.10 209 419 1.5E-39 T 13-09-2016 IPR016188 PurM-like, N-terminal domain THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 Gene3D G3DSA:3.30.1330.10 644 808 3.0E-13 T 13-09-2016 IPR016188 PurM-like, N-terminal domain THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 SUPERFAMILY SSF52317 1039 1297 7.08E-96 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS06205 37b17a0408d25c450a24e8c05b0599d3 1298 SUPERFAMILY SSF56042 430 612 4.49E-54 T 13-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain THL1_RS07670 c782bc13971afd2fd2e2e86d7f6c07bb 308 PANTHER PTHR33711:SF4 1 306 1.5E-119 T 13-09-2016 THL1_RS07670 c782bc13971afd2fd2e2e86d7f6c07bb 308 Pfam PF04444 Catechol dioxygenase N terminus 28 95 5.0E-20 T 13-09-2016 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 THL1_RS07670 c782bc13971afd2fd2e2e86d7f6c07bb 308 TIGRFAM TIGR02439 catechol_proteo: catechol 1,2-dioxygenase 9 289 7.9E-143 T 13-09-2016 IPR012801 Catechol 1,2-dioxygenase, proteobacteria GO:0005506|GO:0018576|GO:0019614|GO:0055114 KEGG: 00361+1.13.11.1|KEGG: 00362+1.13.11.1|KEGG: 00364+1.13.11.1|KEGG: 00623+1.13.11.1|UniPathway: UPA00157 THL1_RS07670 c782bc13971afd2fd2e2e86d7f6c07bb 308 SUPERFAMILY SSF49482 5 292 1.14E-92 T 13-09-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 THL1_RS07670 c782bc13971afd2fd2e2e86d7f6c07bb 308 Pfam PF00775 Dioxygenase 105 290 2.7E-69 T 13-09-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 THL1_RS07670 c782bc13971afd2fd2e2e86d7f6c07bb 308 PANTHER PTHR33711 1 306 1.5E-119 T 13-09-2016 THL1_RS07670 c782bc13971afd2fd2e2e86d7f6c07bb 308 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 135 163 - T 13-09-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 THL1_RS07670 c782bc13971afd2fd2e2e86d7f6c07bb 308 Gene3D G3DSA:2.60.130.10 2 307 1.1E-103 T 13-09-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 SUPERFAMILY SSF82714 707 792 7.85E-18 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 SUPERFAMILY SSF82714 183 265 3.14E-15 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 8.1E-80 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 8.1E-80 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 PRINTS PR00702 Acriflavin resistance protein family signature 607 621 8.1E-80 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 8.1E-80 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 8.1E-80 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 8.1E-80 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 8.1E-80 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 8.1E-80 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 8.1E-80 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 SUPERFAMILY SSF82866 290 491 8.5E-48 T 13-09-2016 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 Gene3D G3DSA:1.20.1640.10 284 498 4.2E-59 T 13-09-2016 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 SUPERFAMILY SSF82693 137 182 2.2E-20 T 13-09-2016 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 SUPERFAMILY SSF82693 268 324 2.2E-20 T 13-09-2016 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 Gene3D G3DSA:1.10.3850.10 799 1014 4.5E-50 T 13-09-2016 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 PANTHER PTHR32063 1 1034 0.0 T 13-09-2016 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 SUPERFAMILY SSF82693 40 130 5.75E-23 T 13-09-2016 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 Gene3D G3DSA:3.30.70.1430 41 142 5.2E-29 T 13-09-2016 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 SUPERFAMILY SSF82693 556 648 2.62E-14 T 13-09-2016 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 SUPERFAMILY SSF82866 791 1017 4.58E-44 T 13-09-2016 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 Gene3D G3DSA:3.30.2090.10 183 264 2.0E-16 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 Gene3D G3DSA:3.30.2090.10 707 790 6.5E-18 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 PANTHER PTHR32063:SF34 1 1034 0.0 T 13-09-2016 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 Pfam PF00873 AcrB/AcrD/AcrF family 6 1012 0.0 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15450 33a50dbd84b602e1da376affec5d4301 1035 Gene3D G3DSA:3.30.70.1430 559 647 1.0E-9 T 13-09-2016 THL1_RS01945 ec79fefc778cf1fa68a82262d54b4c3a 304 Gene3D G3DSA:1.10.3720.10 36 302 1.6E-38 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01945 ec79fefc778cf1fa68a82262d54b4c3a 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 302 2.6E-12 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01945 ec79fefc778cf1fa68a82262d54b4c3a 304 SUPERFAMILY SSF161098 30 298 8.13E-44 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01945 ec79fefc778cf1fa68a82262d54b4c3a 304 PANTHER PTHR30193 9 304 9.5E-49 T 13-09-2016 THL1_RS22400 7b1cb4251c17ec68e6fc051771eb31f2 230 Gene3D G3DSA:2.40.30.70 4 146 1.5E-53 T 13-09-2016 IPR023370 TsaA-like domain THL1_RS22400 7b1cb4251c17ec68e6fc051771eb31f2 230 PANTHER PTHR12818 4 228 1.5E-103 T 13-09-2016 THL1_RS22400 7b1cb4251c17ec68e6fc051771eb31f2 230 Pfam PF01980 Uncharacterised protein family UPF0066 20 138 6.1E-42 T 13-09-2016 IPR023370 TsaA-like domain THL1_RS22400 7b1cb4251c17ec68e6fc051771eb31f2 230 ProSitePatterns PS01318 TsaA-like domain signature. 86 97 - T 13-09-2016 IPR023368 Uncharacterised protein family UPF0066, conserved site THL1_RS22400 7b1cb4251c17ec68e6fc051771eb31f2 230 SUPERFAMILY SSF118196 2 218 9.29E-75 T 13-09-2016 IPR023370 TsaA-like domain THL1_RS22400 7b1cb4251c17ec68e6fc051771eb31f2 230 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 3 142 2.9E-48 T 13-09-2016 IPR023370 TsaA-like domain THL1_RS22400 7b1cb4251c17ec68e6fc051771eb31f2 230 PANTHER PTHR12818:SF6 4 228 1.5E-103 T 13-09-2016 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 368 381 1.8E-27 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 77 89 1.8E-27 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 57 75 1.8E-27 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 190 203 1.8E-27 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 270 289 1.8E-27 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 SUPERFAMILY SSF50621 255 411 2.09E-52 T 13-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 PANTHER PTHR11482 1 415 1.3E-178 T 13-09-2016 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 285 388 2.0E-17 T 13-09-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 SUPERFAMILY SSF51419 26 282 4.84E-81 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 PANTHER PTHR11482:SF5 1 415 1.3E-178 T 13-09-2016 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 Gene3D G3DSA:3.20.20.10 36 267 6.7E-85 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 41 281 6.9E-75 T 13-09-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 8 410 3.9E-158 T 13-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 15 411 42.374 T 13-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 Gene3D G3DSA:2.40.37.10 268 412 3.4E-47 T 13-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 57 75 - T 13-09-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Reactome: REACT_13 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 PRINTS PR01181 Diaminopimelate decarboxylase signature 164 173 6.5E-30 T 13-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 PRINTS PR01181 Diaminopimelate decarboxylase signature 298 316 6.5E-30 T 13-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 PRINTS PR01181 Diaminopimelate decarboxylase signature 378 400 6.5E-30 T 13-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS27495 5b1aef9c2f47e93eee0ea5a13e973022 415 PRINTS PR01181 Diaminopimelate decarboxylase signature 75 92 6.5E-30 T 13-09-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS25450 140191e5f6d8a5fd35f88c2b18d5918b 654 Gene3D G3DSA:1.10.287.950 407 620 2.5E-50 T 13-09-2016 THL1_RS25450 140191e5f6d8a5fd35f88c2b18d5918b 654 PANTHER PTHR32089 360 654 9.9E-84 T 13-09-2016 THL1_RS25450 140191e5f6d8a5fd35f88c2b18d5918b 654 PANTHER PTHR32089 4 62 9.9E-84 T 13-09-2016 THL1_RS25450 140191e5f6d8a5fd35f88c2b18d5918b 654 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 457 652 2.3E-42 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS25450 140191e5f6d8a5fd35f88c2b18d5918b 654 SMART SM00283 392 653 1.4E-53 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS25450 140191e5f6d8a5fd35f88c2b18d5918b 654 SUPERFAMILY SSF58104 361 654 4.62E-64 T 13-09-2016 THL1_RS04520 2c5d57d99e387b75fe39e26f07d42005 274 Pfam PF00196 Bacterial regulatory proteins, luxR family 201 253 1.7E-15 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS04520 2c5d57d99e387b75fe39e26f07d42005 274 ProSitePatterns PS00622 LuxR-type HTH domain signature. 216 243 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS04520 2c5d57d99e387b75fe39e26f07d42005 274 Gene3D G3DSA:1.10.10.10 201 258 4.0E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS04520 2c5d57d99e387b75fe39e26f07d42005 274 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 232 244 1.1E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS04520 2c5d57d99e387b75fe39e26f07d42005 274 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 202 216 1.1E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS04520 2c5d57d99e387b75fe39e26f07d42005 274 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 216 232 1.1E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS04520 2c5d57d99e387b75fe39e26f07d42005 274 PANTHER PTHR26402:SF572 202 260 3.9E-18 T 13-09-2016 THL1_RS04520 2c5d57d99e387b75fe39e26f07d42005 274 SUPERFAMILY SSF46894 194 257 1.16E-16 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS04520 2c5d57d99e387b75fe39e26f07d42005 274 Gene3D G3DSA:3.30.450.80 22 152 5.4E-5 T 13-09-2016 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain THL1_RS04520 2c5d57d99e387b75fe39e26f07d42005 274 PANTHER PTHR26402 202 260 3.9E-18 T 13-09-2016 THL1_RS04520 2c5d57d99e387b75fe39e26f07d42005 274 SMART SM00421 199 256 6.6E-18 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS04520 2c5d57d99e387b75fe39e26f07d42005 274 SUPERFAMILY SSF75516 9 148 7.19E-6 T 13-09-2016 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain THL1_RS02495 cbf90ad54b3bdc391e09b525d15748fd 425 Pfam PF01168 Alanine racemase, N-terminal domain 56 293 8.2E-21 T 13-09-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS02495 cbf90ad54b3bdc391e09b525d15748fd 425 Gene3D G3DSA:3.20.20.10 59 217 1.9E-7 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS02495 cbf90ad54b3bdc391e09b525d15748fd 425 SUPERFAMILY SSF51419 57 294 3.27E-20 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS19670 1ed308eb15ebb65e2dcce92efc3d81fb 690 PANTHER PTHR30033:SF1 1 494 7.7E-110 T 13-09-2016 THL1_RS19670 1ed308eb15ebb65e2dcce92efc3d81fb 690 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 4 346 2.2E-81 T 13-09-2016 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 THL1_RS19670 1ed308eb15ebb65e2dcce92efc3d81fb 690 PANTHER PTHR30033 550 690 7.7E-110 T 13-09-2016 THL1_RS19670 1ed308eb15ebb65e2dcce92efc3d81fb 690 PANTHER PTHR30033 1 494 7.7E-110 T 13-09-2016 THL1_RS19670 1ed308eb15ebb65e2dcce92efc3d81fb 690 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 637 687 2.7E-7 T 13-09-2016 IPR010930 Flagellar basal-body/hook protein, C-terminal domain THL1_RS19670 1ed308eb15ebb65e2dcce92efc3d81fb 690 PRINTS PR01005 Flagellar hook-associated protein signature 11 34 1.6E-12 T 13-09-2016 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 THL1_RS19670 1ed308eb15ebb65e2dcce92efc3d81fb 690 PRINTS PR01005 Flagellar hook-associated protein signature 156 180 1.6E-12 T 13-09-2016 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 THL1_RS19670 1ed308eb15ebb65e2dcce92efc3d81fb 690 PRINTS PR01005 Flagellar hook-associated protein signature 123 143 1.6E-12 T 13-09-2016 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 THL1_RS19670 1ed308eb15ebb65e2dcce92efc3d81fb 690 PRINTS PR01005 Flagellar hook-associated protein signature 49 71 1.6E-12 T 13-09-2016 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 THL1_RS19670 1ed308eb15ebb65e2dcce92efc3d81fb 690 Pfam PF00460 Flagella basal body rod protein 5 34 4.3E-6 T 13-09-2016 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 THL1_RS19670 1ed308eb15ebb65e2dcce92efc3d81fb 690 PANTHER PTHR30033:SF1 550 690 7.7E-110 T 13-09-2016 THL1_RS19670 1ed308eb15ebb65e2dcce92efc3d81fb 690 SUPERFAMILY SSF64518 147 364 1.57E-32 T 13-09-2016 THL1_RS19670 1ed308eb15ebb65e2dcce92efc3d81fb 690 SUPERFAMILY SSF64518 506 690 1.57E-32 T 13-09-2016 THL1_RS24600 a12dda12350da837109cbc576bab4bfa 361 Gene3D G3DSA:3.60.70.12 4 355 3.8E-116 T 13-09-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 THL1_RS24600 a12dda12350da837109cbc576bab4bfa 361 Pfam PF03576 Peptidase family S58 21 339 1.0E-101 T 13-09-2016 IPR005321 Peptidase S58, DmpA THL1_RS24600 a12dda12350da837109cbc576bab4bfa 361 SUPERFAMILY SSF56266 3 337 4.45E-107 T 13-09-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 THL1_RS24600 a12dda12350da837109cbc576bab4bfa 361 PANTHER PTHR36512:SF1 4 361 1.9E-130 T 13-09-2016 THL1_RS24600 a12dda12350da837109cbc576bab4bfa 361 PANTHER PTHR36512 4 361 1.9E-130 T 13-09-2016 THL1_RS02150 3f05e33479548068654f08acc33c7a7c 254 PIRSF PIRSF005763 1 253 7.4E-83 T 13-09-2016 IPR016462 Molybdate-dependent transcriptional regulator ModE GO:0006355|GO:0015689|GO:0030151 THL1_RS02150 3f05e33479548068654f08acc33c7a7c 254 Pfam PF03459 TOBE domain 115 178 7.6E-18 T 13-09-2016 IPR005116 Transport-associated OB, type 1 THL1_RS02150 3f05e33479548068654f08acc33c7a7c 254 Pfam PF03459 TOBE domain 187 249 5.8E-12 T 13-09-2016 IPR005116 Transport-associated OB, type 1 THL1_RS02150 3f05e33479548068654f08acc33c7a7c 254 SUPERFAMILY SSF50331 113 178 3.21E-18 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS02150 3f05e33479548068654f08acc33c7a7c 254 SUPERFAMILY SSF50331 189 252 2.09E-10 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS02150 3f05e33479548068654f08acc33c7a7c 254 TIGRFAM TIGR00637 ModE_repress: ModE molybdate transport repressor domain 15 103 2.7E-30 T 13-09-2016 IPR003725 Molybdenum-binding protein ModE, N-terminal THL1_RS02150 3f05e33479548068654f08acc33c7a7c 254 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 79 4.4E-16 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS02150 3f05e33479548068654f08acc33c7a7c 254 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 113 178 3.0E-19 T 13-09-2016 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 THL1_RS02150 3f05e33479548068654f08acc33c7a7c 254 SUPERFAMILY SSF46785 10 99 1.01E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02150 3f05e33479548068654f08acc33c7a7c 254 Gene3D G3DSA:1.10.10.10 7 110 6.5E-37 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02150 3f05e33479548068654f08acc33c7a7c 254 Gene3D G3DSA:2.40.50.100 174 243 8.7E-14 T 13-09-2016 THL1_RS02150 3f05e33479548068654f08acc33c7a7c 254 Gene3D G3DSA:2.40.50.100 111 173 2.1E-25 T 13-09-2016 THL1_RS02150 3f05e33479548068654f08acc33c7a7c 254 PANTHER PTHR30432 9 254 3.7E-44 T 13-09-2016 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 Gene3D G3DSA:1.10.274.10 428 526 8.2E-29 T 13-09-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 PANTHER PTHR22931:SF15 435 935 1.7E-237 T 13-09-2016 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 PRINTS PR00107 Phosphocarrier protein signature 337 354 2.2E-7 T 13-09-2016 IPR000032 Phosphocarrier HPr protein-like THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 PRINTS PR00107 Phosphocarrier protein signature 294 310 2.2E-7 T 13-09-2016 IPR000032 Phosphocarrier HPr protein-like THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 PRINTS PR00107 Phosphocarrier protein signature 322 337 2.2E-7 T 13-09-2016 IPR000032 Phosphocarrier HPr protein-like THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 832 850 - T 13-09-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 Pfam PF05524 PEP-utilising enzyme, N-terminal 405 519 7.3E-22 T 13-09-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 SUPERFAMILY SSF52009 518 634 3.14E-32 T 13-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 Gene3D G3DSA:3.50.30.10 527 641 3.0E-36 T 13-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 406 949 2.7E-145 T 13-09-2016 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 SUPERFAMILY SSF47831 428 536 9.02E-25 T 13-09-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 575 586 - T 13-09-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 648 924 1.5E-102 T 13-09-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 832 847 1.5E-19 T 13-09-2016 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 849 864 1.5E-19 T 13-09-2016 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 885 897 1.5E-19 T 13-09-2016 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 684 703 1.5E-19 T 13-09-2016 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 SUPERFAMILY SSF55804 148 274 4.32E-14 T 13-09-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 141 8.6E-25 T 13-09-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 Gene3D G3DSA:3.20.20.60 649 951 3.4E-103 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 Gene3D G3DSA:3.30.1340.10 286 372 1.5E-20 T 13-09-2016 IPR000032 Phosphocarrier HPr protein-like THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 Pfam PF00391 PEP-utilising enzyme, mobile domain 544 616 9.3E-22 T 13-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 SUPERFAMILY SSF55594 284 371 2.09E-17 T 13-09-2016 IPR000032 Phosphocarrier HPr protein-like THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 SUPERFAMILY SSF55804 4 140 1.19E-32 T 13-09-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 Pfam PF00381 PTS HPr component phosphorylation site 289 366 1.2E-16 T 13-09-2016 IPR000032 Phosphocarrier HPr protein-like THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 PANTHER PTHR22931 435 935 1.7E-237 T 13-09-2016 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 SUPERFAMILY SSF51621 647 934 2.49E-99 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 47 63 - T 13-09-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 Gene3D G3DSA:3.40.930.10 4 143 5.2E-33 T 13-09-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- THL1_RS08320 b7bdb0c33c51c890f25bd786914b963f 953 Gene3D G3DSA:3.40.930.10 148 276 4.8E-11 T 13-09-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- THL1_RS14605 885364b70ad1afb6edb02da0c365c2e9 403 PANTHER PTHR21266 9 393 4.1E-76 T 13-09-2016 THL1_RS14605 885364b70ad1afb6edb02da0c365c2e9 403 PANTHER PTHR21266:SF2 9 393 4.1E-76 T 13-09-2016 THL1_RS14605 885364b70ad1afb6edb02da0c365c2e9 403 Pfam PF00355 Rieske [2Fe-2S] domain 43 118 1.6E-16 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS14605 885364b70ad1afb6edb02da0c365c2e9 403 Gene3D G3DSA:3.90.380.10 146 393 6.9E-15 T 13-09-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 THL1_RS14605 885364b70ad1afb6edb02da0c365c2e9 403 Gene3D G3DSA:2.102.10.10 41 145 7.8E-34 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS14605 885364b70ad1afb6edb02da0c365c2e9 403 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 174 398 4.5E-41 T 13-09-2016 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 THL1_RS14605 885364b70ad1afb6edb02da0c365c2e9 403 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 27 52 2.4E-21 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS14605 885364b70ad1afb6edb02da0c365c2e9 403 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 57 72 2.4E-21 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS14605 885364b70ad1afb6edb02da0c365c2e9 403 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 175 197 2.4E-21 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS14605 885364b70ad1afb6edb02da0c365c2e9 403 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 99 119 2.4E-21 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS14605 885364b70ad1afb6edb02da0c365c2e9 403 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 78 98 2.4E-21 T 13-09-2016 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 THL1_RS14605 885364b70ad1afb6edb02da0c365c2e9 403 SUPERFAMILY SSF55961 155 400 3.77E-53 T 13-09-2016 THL1_RS14605 885364b70ad1afb6edb02da0c365c2e9 403 SUPERFAMILY SSF50022 10 153 6.29E-46 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS04850 8d4b6ec8f17c78891a221a97452905cd 511 PIRSF PIRSF002869 1 511 4.7E-171 T 13-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ THL1_RS04850 8d4b6ec8f17c78891a221a97452905cd 511 PANTHER PTHR11206 469 484 1.0E-97 T 13-09-2016 THL1_RS04850 8d4b6ec8f17c78891a221a97452905cd 511 PANTHER PTHR11206 217 442 1.0E-97 T 13-09-2016 THL1_RS04850 8d4b6ec8f17c78891a221a97452905cd 511 PANTHER PTHR11206 70 82 1.0E-97 T 13-09-2016 THL1_RS04850 8d4b6ec8f17c78891a221a97452905cd 511 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 504 2.0E-162 T 13-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ THL1_RS04850 8d4b6ec8f17c78891a221a97452905cd 511 PANTHER PTHR11206:SF90 469 484 1.0E-97 T 13-09-2016 THL1_RS04850 8d4b6ec8f17c78891a221a97452905cd 511 PANTHER PTHR11206:SF90 217 442 1.0E-97 T 13-09-2016 THL1_RS04850 8d4b6ec8f17c78891a221a97452905cd 511 PANTHER PTHR11206:SF90 70 82 1.0E-97 T 13-09-2016 THL1_RS04850 8d4b6ec8f17c78891a221a97452905cd 511 Pfam PF03023 MviN-like protein 28 477 6.1E-153 T 13-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ THL1_RS04850 8d4b6ec8f17c78891a221a97452905cd 511 PRINTS PR01806 Virulence factor MviN signature 33 52 2.6E-85 T 13-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ THL1_RS04850 8d4b6ec8f17c78891a221a97452905cd 511 PRINTS PR01806 Virulence factor MviN signature 133 157 2.6E-85 T 13-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ THL1_RS04850 8d4b6ec8f17c78891a221a97452905cd 511 PRINTS PR01806 Virulence factor MviN signature 157 178 2.6E-85 T 13-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ THL1_RS04850 8d4b6ec8f17c78891a221a97452905cd 511 PRINTS PR01806 Virulence factor MviN signature 357 376 2.6E-85 T 13-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ THL1_RS04850 8d4b6ec8f17c78891a221a97452905cd 511 PRINTS PR01806 Virulence factor MviN signature 52 68 2.6E-85 T 13-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ THL1_RS04850 8d4b6ec8f17c78891a221a97452905cd 511 PRINTS PR01806 Virulence factor MviN signature 409 426 2.6E-85 T 13-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ THL1_RS04850 8d4b6ec8f17c78891a221a97452905cd 511 PRINTS PR01806 Virulence factor MviN signature 259 285 2.6E-85 T 13-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ THL1_RS24460 a6258368ac20dc6688e31ee92e75f189 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 156 7.8E-28 T 13-09-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 THL1_RS24460 a6258368ac20dc6688e31ee92e75f189 158 SUPERFAMILY SSF54534 82 156 1.02E-23 T 13-09-2016 THL1_RS24460 a6258368ac20dc6688e31ee92e75f189 158 SUPERFAMILY SSF46557 3 77 5.1E-28 T 13-09-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 THL1_RS24460 a6258368ac20dc6688e31ee92e75f189 158 Gene3D G3DSA:3.10.50.30 81 156 1.5E-30 T 13-09-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 THL1_RS24460 a6258368ac20dc6688e31ee92e75f189 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 33.064 T 13-09-2016 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 THL1_RS24460 a6258368ac20dc6688e31ee92e75f189 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 13-09-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 THL1_RS24460 a6258368ac20dc6688e31ee92e75f189 158 Gene3D G3DSA:1.10.287.180 1 75 6.5E-33 T 13-09-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 THL1_RS24460 a6258368ac20dc6688e31ee92e75f189 158 PANTHER PTHR30437 1 156 3.1E-65 T 13-09-2016 THL1_RS24460 a6258368ac20dc6688e31ee92e75f189 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 13-09-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 THL1_RS24460 a6258368ac20dc6688e31ee92e75f189 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 155 2.6E-56 T 13-09-2016 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 THL1_RS24460 a6258368ac20dc6688e31ee92e75f189 158 Pfam PF03449 Transcription elongation factor, N-terminal 5 74 3.6E-30 T 13-09-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 THL1_RS24460 a6258368ac20dc6688e31ee92e75f189 158 PIRSF PIRSF006092 1 158 1.6E-51 T 13-09-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 THL1_RS21585 5dba253d71dc5c6c766506fa161bebe7 200 Gene3D G3DSA:3.30.1020.10 157 194 1.8E-16 T 13-09-2016 THL1_RS21585 5dba253d71dc5c6c766506fa161bebe7 200 Pfam PF00578 AhpC/TSA family 5 139 4.6E-34 T 13-09-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS21585 5dba253d71dc5c6c766506fa161bebe7 200 SUPERFAMILY SSF52833 3 194 1.79E-67 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS21585 5dba253d71dc5c6c766506fa161bebe7 200 Gene3D G3DSA:3.40.30.10 2 156 2.8E-56 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS21585 5dba253d71dc5c6c766506fa161bebe7 200 PIRSF PIRSF000239 1 198 5.1E-59 T 13-09-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 THL1_RS21585 5dba253d71dc5c6c766506fa161bebe7 200 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 160 193 2.4E-14 T 13-09-2016 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS21585 5dba253d71dc5c6c766506fa161bebe7 200 PANTHER PTHR10681 3 194 5.1E-86 T 13-09-2016 THL1_RS26860 65e07ea0267d6a82bf875901a1bd22cd 405 Pfam PF13356 Domain of unknown function (DUF4102) 3 86 8.5E-16 T 13-09-2016 IPR025166 Domain of unknown function DUF4102 THL1_RS26860 65e07ea0267d6a82bf875901a1bd22cd 405 PANTHER PTHR30629 1 390 5.3E-172 T 13-09-2016 THL1_RS26860 65e07ea0267d6a82bf875901a1bd22cd 405 Gene3D G3DSA:1.10.150.130 98 195 5.8E-14 T 13-09-2016 IPR023109 Integrase/recombinase, N-terminal THL1_RS26860 65e07ea0267d6a82bf875901a1bd22cd 405 SUPERFAMILY SSF56349 98 380 1.0E-60 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS26860 65e07ea0267d6a82bf875901a1bd22cd 405 Gene3D G3DSA:1.10.443.10 209 376 4.1E-25 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS26860 65e07ea0267d6a82bf875901a1bd22cd 405 Pfam PF00589 Phage integrase family 211 370 6.0E-24 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS26860 65e07ea0267d6a82bf875901a1bd22cd 405 PANTHER PTHR30629:SF3 1 390 5.3E-172 T 13-09-2016 THL1_RS25025 cdfe340ffa23eb79cd3e4177d84fd3cf 199 PANTHER PTHR39583 1 191 5.3E-25 T 13-09-2016 THL1_RS25025 cdfe340ffa23eb79cd3e4177d84fd3cf 199 SUPERFAMILY SSF54523 45 193 2.16E-31 T 13-09-2016 THL1_RS25025 cdfe340ffa23eb79cd3e4177d84fd3cf 199 Gene3D G3DSA:2.10.70.20 144 193 7.6E-7 T 13-09-2016 THL1_RS25025 cdfe340ffa23eb79cd3e4177d84fd3cf 199 Gene3D G3DSA:3.10.610.10 35 133 1.3E-19 T 13-09-2016 THL1_RS25025 cdfe340ffa23eb79cd3e4177d84fd3cf 199 Pfam PF11612 Type II secretion system (T2SS), protein J 56 187 2.3E-27 T 13-09-2016 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 THL1_RS25025 cdfe340ffa23eb79cd3e4177d84fd3cf 199 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 23 3.5E-7 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS25025 cdfe340ffa23eb79cd3e4177d84fd3cf 199 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS25025 cdfe340ffa23eb79cd3e4177d84fd3cf 199 Pfam PF13633 Prokaryotic N-terminal methylation site 3 29 8.5E-9 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS25025 cdfe340ffa23eb79cd3e4177d84fd3cf 199 TIGRFAM TIGR01711 gspJ: type II secretion system protein J 4 189 1.8E-38 T 13-09-2016 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 THL1_RS25025 cdfe340ffa23eb79cd3e4177d84fd3cf 199 PANTHER PTHR39583:SF1 1 191 5.3E-25 T 13-09-2016 THL1_RS28035 64b1963a28373a1aca475ec2a06d9643 763 SUPERFAMILY SSF50978 109 389 1.65E-5 T 13-09-2016 IPR017986 WD40-repeat-containing domain GO:0005515 THL1_RS28035 64b1963a28373a1aca475ec2a06d9643 763 PANTHER PTHR30425:SF3 319 528 1.2E-174 T 13-09-2016 THL1_RS28035 64b1963a28373a1aca475ec2a06d9643 763 PANTHER PTHR30425 594 763 1.2E-174 T 13-09-2016 THL1_RS28035 64b1963a28373a1aca475ec2a06d9643 763 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 480 758 2.7E-10 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS28035 64b1963a28373a1aca475ec2a06d9643 763 Gene3D G3DSA:1.10.3720.10 444 526 2.9E-44 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS28035 64b1963a28373a1aca475ec2a06d9643 763 Gene3D G3DSA:1.10.3720.10 599 760 2.9E-44 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS28035 64b1963a28373a1aca475ec2a06d9643 763 Gene3D G3DSA:1.10.3720.10 49 71 2.9E-44 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS28035 64b1963a28373a1aca475ec2a06d9643 763 PANTHER PTHR30425 319 528 1.2E-174 T 13-09-2016 THL1_RS28035 64b1963a28373a1aca475ec2a06d9643 763 PANTHER PTHR30425:SF3 594 763 1.2E-174 T 13-09-2016 THL1_RS28035 64b1963a28373a1aca475ec2a06d9643 763 SUPERFAMILY SSF161098 458 525 8.0E-18 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS28035 64b1963a28373a1aca475ec2a06d9643 763 SUPERFAMILY SSF161098 609 699 8.0E-18 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07070 b41bbe75a845322c9cbbc6af2da8dfc3 388 PANTHER PTHR10909:SF229 1 388 1.6E-136 T 13-09-2016 THL1_RS07070 b41bbe75a845322c9cbbc6af2da8dfc3 388 Gene3D G3DSA:2.40.110.10 123 220 7.2E-33 T 13-09-2016 THL1_RS07070 b41bbe75a845322c9cbbc6af2da8dfc3 388 SUPERFAMILY SSF47203 230 384 5.48E-19 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS07070 b41bbe75a845322c9cbbc6af2da8dfc3 388 Gene3D G3DSA:1.20.140.10 221 387 1.1E-30 T 13-09-2016 THL1_RS07070 b41bbe75a845322c9cbbc6af2da8dfc3 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 120 1.2E-20 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS07070 b41bbe75a845322c9cbbc6af2da8dfc3 388 PANTHER PTHR10909 1 388 1.6E-136 T 13-09-2016 THL1_RS07070 b41bbe75a845322c9cbbc6af2da8dfc3 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 218 9.0E-21 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS07070 b41bbe75a845322c9cbbc6af2da8dfc3 388 Gene3D G3DSA:1.10.540.10 1 122 1.9E-25 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS07070 b41bbe75a845322c9cbbc6af2da8dfc3 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 383 1.9E-18 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS07070 b41bbe75a845322c9cbbc6af2da8dfc3 388 SUPERFAMILY SSF56645 2 239 1.57E-68 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS25470 62e87849e95570cd2ab530088d274d7d 449 SMART SM00878 336 441 1.0E-64 T 13-09-2016 IPR005482 Biotin carboxylase, C-terminal THL1_RS25470 62e87849e95570cd2ab530088d274d7d 449 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 446 6.3E-230 T 13-09-2016 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 THL1_RS25470 62e87849e95570cd2ab530088d274d7d 449 Gene3D G3DSA:3.30.1490.20 130 203 5.6E-28 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS25470 62e87849e95570cd2ab530088d274d7d 449 SUPERFAMILY SSF51246 331 444 1.88E-43 T 13-09-2016 IPR011054 Rudiment single hybrid motif THL1_RS25470 62e87849e95570cd2ab530088d274d7d 449 Gene3D G3DSA:3.40.50.20 1 129 8.8E-53 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS25470 62e87849e95570cd2ab530088d274d7d 449 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 323 5.9E-85 T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS25470 62e87849e95570cd2ab530088d274d7d 449 SUPERFAMILY SSF56059 83 344 9.72E-68 T 13-09-2016 THL1_RS25470 62e87849e95570cd2ab530088d274d7d 449 SMART SM01209 114 292 0.0024 T 13-09-2016 THL1_RS25470 62e87849e95570cd2ab530088d274d7d 449 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.9E-45 T 13-09-2016 IPR005481 Biotin carboxylase-like, N-terminal domain THL1_RS25470 62e87849e95570cd2ab530088d274d7d 449 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 8.1E-39 T 13-09-2016 IPR005482 Biotin carboxylase, C-terminal THL1_RS25470 62e87849e95570cd2ab530088d274d7d 449 Gene3D G3DSA:3.30.470.20 204 444 1.0E-95 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS25470 62e87849e95570cd2ab530088d274d7d 449 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS25470 62e87849e95570cd2ab530088d274d7d 449 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS25470 62e87849e95570cd2ab530088d274d7d 449 SUPERFAMILY SSF52440 1 113 2.37E-47 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS25470 62e87849e95570cd2ab530088d274d7d 449 PANTHER PTHR18866 1 442 2.8E-293 T 13-09-2016 THL1_RS07770 2b1511e41ca9fc170b6e0baacbc704f8 86 PANTHER PTHR33993 2 83 2.3E-27 T 13-09-2016 THL1_RS07770 2b1511e41ca9fc170b6e0baacbc704f8 86 Gene3D G3DSA:3.10.180.10 16 83 3.4E-13 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS07770 2b1511e41ca9fc170b6e0baacbc704f8 86 PANTHER PTHR33993:SF1 2 83 2.3E-27 T 13-09-2016 THL1_RS07770 2b1511e41ca9fc170b6e0baacbc704f8 86 SUPERFAMILY SSF54593 4 83 2.11E-13 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS02005 8415830edfcc994ee7d4914f3bf11e1b 399 Gene3D G3DSA:3.40.50.720 189 308 7.7E-27 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS02005 8415830edfcc994ee7d4914f3bf11e1b 399 Pfam PF00107 Zinc-binding dehydrogenase 197 266 8.8E-8 T 13-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THL1_RS02005 8415830edfcc994ee7d4914f3bf11e1b 399 PANTHER PTHR11695:SF586 15 396 1.8E-194 T 13-09-2016 THL1_RS02005 8415830edfcc994ee7d4914f3bf11e1b 399 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 67 81 - T 13-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 THL1_RS02005 8415830edfcc994ee7d4914f3bf11e1b 399 Gene3D G3DSA:3.90.180.10 5 188 2.3E-46 T 13-09-2016 IPR011032 GroES-like THL1_RS02005 8415830edfcc994ee7d4914f3bf11e1b 399 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 144 8.6E-27 T 13-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THL1_RS02005 8415830edfcc994ee7d4914f3bf11e1b 399 SUPERFAMILY SSF50129 4 188 4.23E-64 T 13-09-2016 IPR011032 GroES-like THL1_RS02005 8415830edfcc994ee7d4914f3bf11e1b 399 TIGRFAM TIGR02819 fdhA_non_GSH: formaldehyde dehydrogenase, glutathione-independent 2 395 4.1E-233 T 13-09-2016 IPR014184 Formaldehyde dehydrogenase, glutathione-independent GO:0016491|GO:0055114 THL1_RS02005 8415830edfcc994ee7d4914f3bf11e1b 399 SUPERFAMILY SSF51735 162 356 1.18E-65 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS02005 8415830edfcc994ee7d4914f3bf11e1b 399 PANTHER PTHR11695 15 396 1.8E-194 T 13-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 THL1_RS16525 6bf79c7f4be15875416eebc53be5fda2 221 SMART SM00345 22 80 4.4E-13 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS16525 6bf79c7f4be15875416eebc53be5fda2 221 Gene3D G3DSA:1.20.120.530 84 220 8.8E-40 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS16525 6bf79c7f4be15875416eebc53be5fda2 221 Gene3D G3DSA:1.10.10.10 13 81 4.1E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS16525 6bf79c7f4be15875416eebc53be5fda2 221 SUPERFAMILY SSF48008 87 219 5.75E-27 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS16525 6bf79c7f4be15875416eebc53be5fda2 221 SMART SM00895 90 212 4.6E-20 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS16525 6bf79c7f4be15875416eebc53be5fda2 221 PANTHER PTHR11751 9 106 3.0E-37 T 13-09-2016 THL1_RS16525 6bf79c7f4be15875416eebc53be5fda2 221 PANTHER PTHR11751:SF436 9 106 3.0E-37 T 13-09-2016 THL1_RS16525 6bf79c7f4be15875416eebc53be5fda2 221 Pfam PF07729 FCD domain 90 210 5.8E-28 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS16525 6bf79c7f4be15875416eebc53be5fda2 221 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 80 1.3E-15 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS16525 6bf79c7f4be15875416eebc53be5fda2 221 SUPERFAMILY SSF46785 17 84 4.93E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS25500 2c4db3f0727ab61d48ca6ff0aad1a2c9 429 Gene3D G3DSA:3.30.1490.20 120 189 4.4E-34 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS25500 2c4db3f0727ab61d48ca6ff0aad1a2c9 429 Gene3D G3DSA:3.40.50.20 2 94 9.5E-36 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS25500 2c4db3f0727ab61d48ca6ff0aad1a2c9 429 SUPERFAMILY SSF52440 1 102 1.11E-33 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS25500 2c4db3f0727ab61d48ca6ff0aad1a2c9 429 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 330 420 1.4E-29 T 13-09-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 THL1_RS25500 2c4db3f0727ab61d48ca6ff0aad1a2c9 429 PANTHER PTHR10520 1 425 1.6E-286 T 13-09-2016 THL1_RS25500 2c4db3f0727ab61d48ca6ff0aad1a2c9 429 SMART SM01210 329 422 1.1E-54 T 13-09-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 THL1_RS25500 2c4db3f0727ab61d48ca6ff0aad1a2c9 429 SUPERFAMILY SSF56059 103 319 4.6E-64 T 13-09-2016 THL1_RS25500 2c4db3f0727ab61d48ca6ff0aad1a2c9 429 Gene3D G3DSA:3.30.470.20 190 327 1.3E-61 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS25500 2c4db3f0727ab61d48ca6ff0aad1a2c9 429 Gene3D G3DSA:3.90.600.10 330 422 3.7E-35 T 13-09-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 THL1_RS25500 2c4db3f0727ab61d48ca6ff0aad1a2c9 429 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 422 43.082 T 13-09-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 THL1_RS25500 2c4db3f0727ab61d48ca6ff0aad1a2c9 429 SUPERFAMILY SSF51246 328 423 6.28E-33 T 13-09-2016 IPR011054 Rudiment single hybrid motif THL1_RS25500 2c4db3f0727ab61d48ca6ff0aad1a2c9 429 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 422 3.1E-180 T 13-09-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 THL1_RS25500 2c4db3f0727ab61d48ca6ff0aad1a2c9 429 SMART SM01209 102 295 5.2E-142 T 13-09-2016 THL1_RS25500 2c4db3f0727ab61d48ca6ff0aad1a2c9 429 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 101 1.6E-32 T 13-09-2016 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 THL1_RS25500 2c4db3f0727ab61d48ca6ff0aad1a2c9 429 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 289 296 - T 13-09-2016 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 THL1_RS25500 2c4db3f0727ab61d48ca6ff0aad1a2c9 429 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 102 295 2.3E-83 T 13-09-2016 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 THL1_RS17210 2451f99bccd9c817341097ef3ebf50c5 202 Gene3D G3DSA:1.10.357.10 27 174 7.6E-23 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS17210 2451f99bccd9c817341097ef3ebf50c5 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 68 2.3E-12 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS17210 2451f99bccd9c817341097ef3ebf50c5 202 SUPERFAMILY SSF46689 24 82 2.57E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17210 2451f99bccd9c817341097ef3ebf50c5 202 PANTHER PTHR30055 12 145 5.2E-17 T 13-09-2016 THL1_RS19125 d3380a150e7414acbea6c642c715e3b0 433 SUPERFAMILY SSF51905 350 396 4.32E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS19125 d3380a150e7414acbea6c642c715e3b0 433 SUPERFAMILY SSF51905 26 253 4.32E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS19125 d3380a150e7414acbea6c642c715e3b0 433 PANTHER PTHR13847:SF196 1 416 5.8E-56 T 13-09-2016 THL1_RS19125 d3380a150e7414acbea6c642c715e3b0 433 PANTHER PTHR13847 1 416 5.8E-56 T 13-09-2016 THL1_RS19125 d3380a150e7414acbea6c642c715e3b0 433 Gene3D G3DSA:3.50.50.60 171 252 1.0E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS19125 d3380a150e7414acbea6c642c715e3b0 433 Gene3D G3DSA:3.50.50.60 350 395 1.0E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS19125 d3380a150e7414acbea6c642c715e3b0 433 Gene3D G3DSA:3.50.50.60 19 118 1.0E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS19125 d3380a150e7414acbea6c642c715e3b0 433 Pfam PF01266 FAD dependent oxidoreductase 27 387 1.6E-42 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS17025 b9ffad45dae55102b6cbc1f9e2e1f71f 212 Gene3D G3DSA:3.40.50.300 1 210 7.1E-38 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17025 b9ffad45dae55102b6cbc1f9e2e1f71f 212 PANTHER PTHR13696 1 209 3.4E-63 T 13-09-2016 THL1_RS17025 b9ffad45dae55102b6cbc1f9e2e1f71f 212 PANTHER PTHR13696:SF54 1 209 3.4E-63 T 13-09-2016 THL1_RS17025 b9ffad45dae55102b6cbc1f9e2e1f71f 212 PIRSF PIRSF009320 1 211 3.3E-49 T 13-09-2016 THL1_RS17025 b9ffad45dae55102b6cbc1f9e2e1f71f 212 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 144 3.9E-26 T 13-09-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THL1_RS17025 b9ffad45dae55102b6cbc1f9e2e1f71f 212 SUPERFAMILY SSF52540 1 210 1.64E-41 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16350 5669a0a4065e045fd8a038a81cc246b6 308 PANTHER PTHR10683 1 307 2.5E-166 T 13-09-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 THL1_RS16350 5669a0a4065e045fd8a038a81cc246b6 308 Hamap MF_00492 Transaldolase [tal]. 2 308 50.059 T 13-09-2016 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 THL1_RS16350 5669a0a4065e045fd8a038a81cc246b6 308 PANTHER PTHR10683:SF18 1 307 2.5E-166 T 13-09-2016 THL1_RS16350 5669a0a4065e045fd8a038a81cc246b6 308 ProSitePatterns PS01054 Transaldolase signature 1. 31 39 - T 13-09-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 THL1_RS16350 5669a0a4065e045fd8a038a81cc246b6 308 ProSitePatterns PS00958 Transaldolase active site. 122 139 - T 13-09-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 THL1_RS16350 5669a0a4065e045fd8a038a81cc246b6 308 Pfam PF00923 Transaldolase 14 303 1.3E-96 T 13-09-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 THL1_RS16350 5669a0a4065e045fd8a038a81cc246b6 308 Gene3D G3DSA:3.20.20.70 2 307 1.4E-120 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS16350 5669a0a4065e045fd8a038a81cc246b6 308 SUPERFAMILY SSF51569 1 307 5.23E-109 T 13-09-2016 THL1_RS16350 5669a0a4065e045fd8a038a81cc246b6 308 TIGRFAM TIGR00874 talAB: transaldolase 4 305 3.3E-136 T 13-09-2016 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 THL1_RS12200 71b138ab17f197ba58ecaf13e803514e 430 Gene3D G3DSA:1.10.8.60 300 369 3.8E-20 T 13-09-2016 THL1_RS12200 71b138ab17f197ba58ecaf13e803514e 430 Gene3D G3DSA:1.10.10.60 378 429 3.8E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS12200 71b138ab17f197ba58ecaf13e803514e 430 Pfam PF00158 Sigma-54 interaction domain 140 284 1.1E-30 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS12200 71b138ab17f197ba58ecaf13e803514e 430 SMART SM00382 160 292 5.3E-4 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS12200 71b138ab17f197ba58ecaf13e803514e 430 SUPERFAMILY SSF46689 340 429 2.09E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS12200 71b138ab17f197ba58ecaf13e803514e 430 PANTHER PTHR32071 1 429 2.7E-124 T 13-09-2016 THL1_RS12200 71b138ab17f197ba58ecaf13e803514e 430 Gene3D G3DSA:3.40.50.300 137 299 1.2E-40 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS12200 71b138ab17f197ba58ecaf13e803514e 430 PANTHER PTHR32071:SF34 1 429 2.7E-124 T 13-09-2016 THL1_RS12200 71b138ab17f197ba58ecaf13e803514e 430 Pfam PF02954 Bacterial regulatory protein, Fis family 390 423 1.8E-6 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS12200 71b138ab17f197ba58ecaf13e803514e 430 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 164 177 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS12200 71b138ab17f197ba58ecaf13e803514e 430 SUPERFAMILY SSF52540 140 368 3.31E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11690 0873f0c8122959bcf7a7328a27afe34f 315 Pfam PF01882 Protein of unknown function DUF58 211 284 2.8E-13 T 13-09-2016 IPR002881 Domain of unknown function DUF58 THL1_RS11690 0873f0c8122959bcf7a7328a27afe34f 315 PANTHER PTHR34351:SF1 6 311 5.3E-72 T 13-09-2016 THL1_RS11690 0873f0c8122959bcf7a7328a27afe34f 315 PANTHER PTHR34351 6 311 5.3E-72 T 13-09-2016 THL1_RS05085 1d208b1fe9a8f12355431927ed12ae13 135 PANTHER PTHR30093 1 62 5.7E-20 T 13-09-2016 THL1_RS05085 1d208b1fe9a8f12355431927ed12ae13 135 Pfam PF13633 Prokaryotic N-terminal methylation site 4 30 2.1E-13 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS05085 1d208b1fe9a8f12355431927ed12ae13 135 Gene3D G3DSA:3.30.700.10 7 125 1.5E-37 T 13-09-2016 THL1_RS05085 1d208b1fe9a8f12355431927ed12ae13 135 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 27 5.6E-11 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS05085 1d208b1fe9a8f12355431927ed12ae13 135 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS05085 1d208b1fe9a8f12355431927ed12ae13 135 SUPERFAMILY SSF54523 7 127 2.41E-28 T 13-09-2016 THL1_RS05085 1d208b1fe9a8f12355431927ed12ae13 135 Pfam PF00114 Pilin (bacterial filament) 36 126 1.1E-7 T 13-09-2016 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 THL1_RS10120 22b381cc902b39cebeca08e131e008d2 170 PANTHER PTHR36926:SF1 2 162 1.3E-68 T 13-09-2016 THL1_RS10120 22b381cc902b39cebeca08e131e008d2 170 Pfam PF02674 Colicin V production protein 6 144 1.4E-33 T 13-09-2016 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 THL1_RS10120 22b381cc902b39cebeca08e131e008d2 170 PANTHER PTHR36926 2 162 1.3E-68 T 13-09-2016 THL1_RS26415 320d4b2130791be82f3a50feeabc3e86 91 TIGRFAM TIGR02610 PHA_gran_rgn: putative polyhydroxyalkanoic acid system protein 2 91 4.1E-36 T 13-09-2016 IPR013433 Putative polyhydroxyalkanoic acid system protein THL1_RS26415 320d4b2130791be82f3a50feeabc3e86 91 Pfam PF09650 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) 4 90 2.5E-34 T 13-09-2016 IPR013433 Putative polyhydroxyalkanoic acid system protein THL1_RS16415 e77975829cbe52caacb5f02496b58818 314 Gene3D G3DSA:3.20.20.70 2 310 3.8E-70 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS16415 e77975829cbe52caacb5f02496b58818 314 SMART SM01130 5 301 2.0E-41 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS16415 e77975829cbe52caacb5f02496b58818 314 PANTHER PTHR12128:SF15 1 292 1.0E-63 T 13-09-2016 THL1_RS16415 e77975829cbe52caacb5f02496b58818 314 Pfam PF00701 Dihydrodipicolinate synthetase family 6 237 2.0E-28 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS16415 e77975829cbe52caacb5f02496b58818 314 PANTHER PTHR12128 1 292 1.0E-63 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS16415 e77975829cbe52caacb5f02496b58818 314 SUPERFAMILY SSF51569 4 272 7.01E-51 T 13-09-2016 THL1_RS16415 e77975829cbe52caacb5f02496b58818 314 PRINTS PR00146 Dihydrodipicolinate synthase signature 39 60 6.4E-7 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS16415 e77975829cbe52caacb5f02496b58818 314 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 6.4E-7 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS16415 e77975829cbe52caacb5f02496b58818 314 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 6.4E-7 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS16415 e77975829cbe52caacb5f02496b58818 314 PIRSF PIRSF001365 1 313 5.4E-60 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS01540 d046e892852d172bfb78581414502494 286 Pfam PF01739 CheR methyltransferase, SAM binding domain 86 270 3.5E-55 T 13-09-2016 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal THL1_RS01540 d046e892852d172bfb78581414502494 286 Pfam PF03705 CheR methyltransferase, all-alpha domain 18 70 3.2E-9 T 13-09-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THL1_RS01540 d046e892852d172bfb78581414502494 286 Gene3D G3DSA:3.40.50.150 85 277 1.3E-57 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS01540 d046e892852d172bfb78581414502494 286 PRINTS PR00996 Glutamate methyltransferase family signature 241 264 8.0E-38 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS01540 d046e892852d172bfb78581414502494 286 PRINTS PR00996 Glutamate methyltransferase family signature 117 137 8.0E-38 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS01540 d046e892852d172bfb78581414502494 286 PRINTS PR00996 Glutamate methyltransferase family signature 153 169 8.0E-38 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS01540 d046e892852d172bfb78581414502494 286 PRINTS PR00996 Glutamate methyltransferase family signature 39 52 8.0E-38 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS01540 d046e892852d172bfb78581414502494 286 PRINTS PR00996 Glutamate methyltransferase family signature 79 91 8.0E-38 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS01540 d046e892852d172bfb78581414502494 286 PRINTS PR00996 Glutamate methyltransferase family signature 222 236 8.0E-38 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS01540 d046e892852d172bfb78581414502494 286 Gene3D G3DSA:1.10.155.10 8 84 3.4E-18 T 13-09-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THL1_RS01540 d046e892852d172bfb78581414502494 286 PANTHER PTHR24422:SF13 5 286 7.5E-120 T 13-09-2016 THL1_RS01540 d046e892852d172bfb78581414502494 286 PANTHER PTHR24422 5 286 7.5E-120 T 13-09-2016 THL1_RS01540 d046e892852d172bfb78581414502494 286 SUPERFAMILY SSF47757 8 85 6.28E-14 T 13-09-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THL1_RS01540 d046e892852d172bfb78581414502494 286 SUPERFAMILY SSF53335 87 275 2.84E-46 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS01540 d046e892852d172bfb78581414502494 286 SMART SM00138 17 282 3.0E-103 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS05500 52115e9e2b461452472498b4998cde68 364 SUPERFAMILY SSF52540 55 196 3.55E-14 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05500 52115e9e2b461452472498b4998cde68 364 PANTHER PTHR12169:SF11 1 364 1.0E-192 T 13-09-2016 THL1_RS05500 52115e9e2b461452472498b4998cde68 364 Hamap MF_01919 Cell division protein ZapE [zapE]. 1 364 54.452 T 13-09-2016 IPR030870 Cell division protein ZapE GO:0016887|GO:0051301 THL1_RS05500 52115e9e2b461452472498b4998cde68 364 Pfam PF03969 AFG1-like ATPase 1 360 3.9E-163 T 13-09-2016 IPR005654 ATPase, AFG1-like GO:0005524 THL1_RS05500 52115e9e2b461452472498b4998cde68 364 PANTHER PTHR12169 1 364 1.0E-192 T 13-09-2016 IPR005654 ATPase, AFG1-like GO:0005524 THL1_RS05500 52115e9e2b461452472498b4998cde68 364 Gene3D G3DSA:3.40.50.300 5 169 1.3E-24 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17545 e54f214b96f60a8d2799a577ff88306e 266 Gene3D G3DSA:3.40.50.300 64 229 4.0E-25 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17545 e54f214b96f60a8d2799a577ff88306e 266 SMART SM00382 95 232 8.1E-7 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS17545 e54f214b96f60a8d2799a577ff88306e 266 SUPERFAMILY SSF52540 87 230 7.04E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17545 e54f214b96f60a8d2799a577ff88306e 266 Pfam PF01695 IstB-like ATP binding protein 52 228 1.9E-66 T 13-09-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 THL1_RS17545 e54f214b96f60a8d2799a577ff88306e 266 PANTHER PTHR30050 4 236 2.3E-67 T 13-09-2016 THL1_RS17545 e54f214b96f60a8d2799a577ff88306e 266 PANTHER PTHR30050:SF6 4 236 2.3E-67 T 13-09-2016 THL1_RS17545 e54f214b96f60a8d2799a577ff88306e 266 PIRSF PIRSF003073 1 252 2.1E-69 T 13-09-2016 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein THL1_RS07540 c335f2230a5827f5436e2b408c531df6 161 PANTHER PTHR30466 2 161 1.0E-35 T 13-09-2016 THL1_RS07540 c335f2230a5827f5436e2b408c531df6 161 SUPERFAMILY SSF50475 2 155 2.8E-44 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS07540 c335f2230a5827f5436e2b408c531df6 161 Gene3D G3DSA:2.30.110.10 2 153 1.7E-48 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS07540 c335f2230a5827f5436e2b408c531df6 161 SMART SM00903 11 156 1.3E-49 T 13-09-2016 IPR002563 Flavin reductase like domain GO:0010181 THL1_RS07540 c335f2230a5827f5436e2b408c531df6 161 Pfam PF01613 Flavin reductase like domain 11 155 5.1E-34 T 13-09-2016 IPR002563 Flavin reductase like domain GO:0010181 THL1_RS14445 05f7a416e8446838ab168a0b37e66248 177 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 51 69 - T 13-09-2016 IPR030489 Transcription regulator Rrf2-type, conserved site THL1_RS14445 05f7a416e8446838ab168a0b37e66248 177 SUPERFAMILY SSF46785 5 148 2.97E-31 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14445 05f7a416e8446838ab168a0b37e66248 177 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 5 145 5.0E-30 T 13-09-2016 IPR000944 Transcription regulator Rrf2-type THL1_RS14445 05f7a416e8446838ab168a0b37e66248 177 Gene3D G3DSA:1.10.10.10 5 154 2.8E-40 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14445 05f7a416e8446838ab168a0b37e66248 177 PANTHER PTHR33221:SF6 4 167 7.8E-63 T 13-09-2016 THL1_RS14445 05f7a416e8446838ab168a0b37e66248 177 Pfam PF02082 Transcriptional regulator 4 85 1.2E-24 T 13-09-2016 IPR000944 Transcription regulator Rrf2-type THL1_RS14445 05f7a416e8446838ab168a0b37e66248 177 PANTHER PTHR33221 4 167 7.8E-63 T 13-09-2016 THL1_RS24440 2e4a611836dc04e9c36adc748ea135bf 638 Gene3D G3DSA:3.40.50.300 149 333 8.2E-65 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24440 2e4a611836dc04e9c36adc748ea135bf 638 SMART SM00382 186 325 6.4E-26 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS24440 2e4a611836dc04e9c36adc748ea135bf 638 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 625 37.77 T 13-09-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 THL1_RS24440 2e4a611836dc04e9c36adc748ea135bf 638 PANTHER PTHR23076 1 608 0.0 T 13-09-2016 THL1_RS24440 2e4a611836dc04e9c36adc748ea135bf 638 Pfam PF01434 Peptidase family M41 384 595 2.4E-81 T 13-09-2016 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 THL1_RS24440 2e4a611836dc04e9c36adc748ea135bf 638 ProSitePatterns PS00674 AAA-protein family signature. 293 311 - T 13-09-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 THL1_RS24440 2e4a611836dc04e9c36adc748ea135bf 638 Pfam PF06480 FtsH Extracellular 5 72 1.3E-12 T 13-09-2016 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 THL1_RS24440 2e4a611836dc04e9c36adc748ea135bf 638 Gene3D G3DSA:1.10.8.60 334 407 1.9E-28 T 13-09-2016 THL1_RS24440 2e4a611836dc04e9c36adc748ea135bf 638 SUPERFAMILY SSF140990 404 606 1.24E-76 T 13-09-2016 THL1_RS24440 2e4a611836dc04e9c36adc748ea135bf 638 SUPERFAMILY SSF52540 145 393 6.57E-73 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24440 2e4a611836dc04e9c36adc748ea135bf 638 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 190 322 7.8E-46 T 13-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 THL1_RS24440 2e4a611836dc04e9c36adc748ea135bf 638 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 99 596 2.0E-239 T 13-09-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 THL1_RS17265 c5735f28f0e27ef656a072947b68f5f0 703 SUPERFAMILY SSF51735 297 476 7.78E-56 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS17265 c5735f28f0e27ef656a072947b68f5f0 703 SUPERFAMILY SSF48179 481 579 3.74E-20 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS17265 c5735f28f0e27ef656a072947b68f5f0 703 PANTHER PTHR23309:SF9 2 703 2.1E-269 T 13-09-2016 THL1_RS17265 c5735f28f0e27ef656a072947b68f5f0 703 Gene3D G3DSA:1.10.1040.10 483 575 3.1E-18 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS17265 c5735f28f0e27ef656a072947b68f5f0 703 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 608 698 1.5E-8 T 13-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS17265 c5735f28f0e27ef656a072947b68f5f0 703 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 481 574 1.3E-21 T 13-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS17265 c5735f28f0e27ef656a072947b68f5f0 703 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 194 5.6E-35 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS17265 c5735f28f0e27ef656a072947b68f5f0 703 Gene3D G3DSA:3.40.50.720 297 482 4.1E-59 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS17265 c5735f28f0e27ef656a072947b68f5f0 703 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 301 475 2.4E-61 T 13-09-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS17265 c5735f28f0e27ef656a072947b68f5f0 703 Gene3D G3DSA:1.10.1040.10 613 698 9.7E-15 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS17265 c5735f28f0e27ef656a072947b68f5f0 703 Gene3D G3DSA:3.90.226.10 2 283 2.7E-50 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS17265 c5735f28f0e27ef656a072947b68f5f0 703 SUPERFAMILY SSF48179 604 697 2.3E-19 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS17265 c5735f28f0e27ef656a072947b68f5f0 703 SUPERFAMILY SSF52096 3 291 2.01E-53 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS17265 c5735f28f0e27ef656a072947b68f5f0 703 PANTHER PTHR23309 2 703 2.1E-269 T 13-09-2016 THL1_RS25925 271d8a3c1fcae1909390a11ae0a0a004 287 PANTHER PTHR10067 7 283 8.3E-104 T 13-09-2016 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 THL1_RS25925 271d8a3c1fcae1909390a11ae0a0a004 287 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 50 283 4.7E-77 T 13-09-2016 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 THL1_RS25925 271d8a3c1fcae1909390a11ae0a0a004 287 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 10 285 47.916 T 13-09-2016 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 THL1_RS25925 271d8a3c1fcae1909390a11ae0a0a004 287 Pfam PF02666 Phosphatidylserine decarboxylase 63 282 1.3E-61 T 13-09-2016 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|UniPathway: UPA00558 THL1_RS20815 d34fbc29a95f1a468db6c05e5dd26958 195 PANTHER PTHR11403 20 195 7.9E-48 T 13-09-2016 IPR024791 Cytochrome c oxidase subunit III GO:0015002|GO:0016020|GO:0019646 THL1_RS20815 d34fbc29a95f1a468db6c05e5dd26958 195 Gene3D G3DSA:1.20.120.80 16 194 6.2E-41 T 13-09-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 THL1_RS20815 d34fbc29a95f1a468db6c05e5dd26958 195 Pfam PF00510 Cytochrome c oxidase subunit III 19 194 4.4E-9 T 13-09-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 THL1_RS20815 d34fbc29a95f1a468db6c05e5dd26958 195 SUPERFAMILY SSF81452 12 195 1.83E-40 T 13-09-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 THL1_RS20815 d34fbc29a95f1a468db6c05e5dd26958 195 PANTHER PTHR11403:SF6 20 195 7.9E-48 T 13-09-2016 THL1_RS05625 1ee93a657482006e02262e759046a1b2 360 PANTHER PTHR22926 2 360 2.6E-182 T 13-09-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS05625 1ee93a657482006e02262e759046a1b2 360 PANTHER PTHR22926:SF5 2 360 2.6E-182 T 13-09-2016 THL1_RS05625 1ee93a657482006e02262e759046a1b2 360 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 2.5E-5 T 13-09-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS05625 1ee93a657482006e02262e759046a1b2 360 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 13-09-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS05625 1ee93a657482006e02262e759046a1b2 360 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 37 360 1.4E-138 T 13-09-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS05625 1ee93a657482006e02262e759046a1b2 360 ProSitePatterns PS01348 MraY family signature 2. 189 200 - T 13-09-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS05625 1ee93a657482006e02262e759046a1b2 360 Pfam PF00953 Glycosyl transferase family 4 99 284 3.2E-36 T 13-09-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS05625 1ee93a657482006e02262e759046a1b2 360 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 358 24.539 T 13-09-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS04515 b9d95e065f8dcde607c377dce1276b99 442 PANTHER PTHR24031 1 369 4.5E-185 T 13-09-2016 THL1_RS04515 b9d95e065f8dcde607c377dce1276b99 442 SMART SM00490 258 339 3.0E-33 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS04515 b9d95e065f8dcde607c377dce1276b99 442 PANTHER PTHR24031:SF0 1 369 4.5E-185 T 13-09-2016 THL1_RS04515 b9d95e065f8dcde607c377dce1276b99 442 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 153 161 - T 13-09-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site THL1_RS04515 b9d95e065f8dcde607c377dce1276b99 442 Gene3D G3DSA:3.40.50.300 1 218 3.4E-79 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04515 b9d95e065f8dcde607c377dce1276b99 442 SMART SM00487 20 222 2.2E-60 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS04515 b9d95e065f8dcde607c377dce1276b99 442 SUPERFAMILY SSF52540 74 357 1.93E-73 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04515 b9d95e065f8dcde607c377dce1276b99 442 Pfam PF00270 DEAD/DEAH box helicase 26 193 5.9E-47 T 13-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THL1_RS04515 b9d95e065f8dcde607c377dce1276b99 442 Pfam PF00271 Helicase conserved C-terminal domain 235 339 1.3E-26 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS04515 b9d95e065f8dcde607c377dce1276b99 442 Gene3D G3DSA:3.40.50.300 219 373 2.9E-50 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22430 ca84acb8981b9beaf7d4a4a12db28a6d 216 SMART SM00448 4 119 2.0E-17 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS22430 ca84acb8981b9beaf7d4a4a12db28a6d 216 Gene3D G3DSA:1.10.10.10 141 210 3.7E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS22430 ca84acb8981b9beaf7d4a4a12db28a6d 216 Gene3D G3DSA:3.40.50.2300 3 132 2.4E-28 T 13-09-2016 THL1_RS22430 ca84acb8981b9beaf7d4a4a12db28a6d 216 SMART SM00421 150 207 1.1E-23 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS22430 ca84acb8981b9beaf7d4a4a12db28a6d 216 PANTHER PTHR26402:SF474 4 210 2.9E-76 T 13-09-2016 THL1_RS22430 ca84acb8981b9beaf7d4a4a12db28a6d 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 3.4E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS22430 ca84acb8981b9beaf7d4a4a12db28a6d 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 3.4E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS22430 ca84acb8981b9beaf7d4a4a12db28a6d 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 3.4E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS22430 ca84acb8981b9beaf7d4a4a12db28a6d 216 Pfam PF00072 Response regulator receiver domain 6 119 1.8E-20 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS22430 ca84acb8981b9beaf7d4a4a12db28a6d 216 SUPERFAMILY SSF52172 3 173 1.26E-24 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS22430 ca84acb8981b9beaf7d4a4a12db28a6d 216 PANTHER PTHR26402 4 210 2.9E-76 T 13-09-2016 THL1_RS22430 ca84acb8981b9beaf7d4a4a12db28a6d 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS22430 ca84acb8981b9beaf7d4a4a12db28a6d 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 5.2E-18 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS14865 93f11bf3dfa3636ccbe4573692ebfbe6 346 TIGRFAM TIGR01629 rep_II_X: phage/plasmid replication protein, gene II/X family 2 336 2.3E-61 T 13-09-2016 IPR006516 Replication-associated protein G2P GO:0006260 THL1_RS14865 93f11bf3dfa3636ccbe4573692ebfbe6 346 Pfam PF05144 Phage replication protein CRI 1 223 2.8E-51 T 13-09-2016 IPR022686 Replication-associated protein G2P, N-terminal GO:0006260 THL1_RS14865 93f11bf3dfa3636ccbe4573692ebfbe6 346 Pfam PF05155 Phage X family 253 336 3.2E-25 T 13-09-2016 IPR022688 Replication-associated protein G2P, C-terminal GO:0006260 THL1_RS14815 93f11bf3dfa3636ccbe4573692ebfbe6 346 TIGRFAM TIGR01629 rep_II_X: phage/plasmid replication protein, gene II/X family 2 336 2.3E-61 T 13-09-2016 IPR006516 Replication-associated protein G2P GO:0006260 THL1_RS14815 93f11bf3dfa3636ccbe4573692ebfbe6 346 Pfam PF05144 Phage replication protein CRI 1 223 2.8E-51 T 13-09-2016 IPR022686 Replication-associated protein G2P, N-terminal GO:0006260 THL1_RS14815 93f11bf3dfa3636ccbe4573692ebfbe6 346 Pfam PF05155 Phage X family 253 336 3.2E-25 T 13-09-2016 IPR022688 Replication-associated protein G2P, C-terminal GO:0006260 THL1_RS24295 a9d37a9e1e8a6202da0e8d11e0f1308f 468 SUPERFAMILY SSF81891 187 424 7.72E-47 T 13-09-2016 THL1_RS24295 a9d37a9e1e8a6202da0e8d11e0f1308f 468 Gene3D G3DSA:1.10.3090.10 189 423 2.1E-48 T 13-09-2016 THL1_RS24295 a9d37a9e1e8a6202da0e8d11e0f1308f 468 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 216 278 6.2E-20 T 13-09-2016 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain THL1_RS24295 a9d37a9e1e8a6202da0e8d11e0f1308f 468 Pfam PF01743 Poly A polymerase head domain 56 189 1.9E-38 T 13-09-2016 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 THL1_RS24295 a9d37a9e1e8a6202da0e8d11e0f1308f 468 PANTHER PTHR13734 5 318 7.4E-125 T 13-09-2016 THL1_RS24295 a9d37a9e1e8a6202da0e8d11e0f1308f 468 PANTHER PTHR13734:SF47 5 318 7.4E-125 T 13-09-2016 THL1_RS24295 a9d37a9e1e8a6202da0e8d11e0f1308f 468 Gene3D G3DSA:3.30.460.10 38 188 2.4E-50 T 13-09-2016 THL1_RS24295 a9d37a9e1e8a6202da0e8d11e0f1308f 468 SUPERFAMILY SSF81301 30 186 1.74E-40 T 13-09-2016 THL1_RS24295 a9d37a9e1e8a6202da0e8d11e0f1308f 468 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 16 458 37.643 T 13-09-2016 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 THL1_RS24295 a9d37a9e1e8a6202da0e8d11e0f1308f 468 Pfam PF12626 Polymerase A arginine-rich C-terminus 332 448 6.1E-43 T 13-09-2016 IPR025866 Polymerase A arginine-rich C-terminal domain THL1_RS24295 a9d37a9e1e8a6202da0e8d11e0f1308f 468 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 26 455 7.8E-183 T 13-09-2016 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 THL1_RS24960 be871905c79132725f94dab780d9ca5a 316 Gene3D G3DSA:3.20.20.140 4 313 2.8E-101 T 13-09-2016 THL1_RS24960 be871905c79132725f94dab780d9ca5a 316 SUPERFAMILY SSF51556 3 312 5.73E-85 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS24960 be871905c79132725f94dab780d9ca5a 316 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 8 312 3.0E-111 T 13-09-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 THL1_RS24960 be871905c79132725f94dab780d9ca5a 316 PANTHER PTHR11409 1 312 2.1E-172 T 13-09-2016 THL1_RS24960 be871905c79132725f94dab780d9ca5a 316 Pfam PF00962 Adenosine/AMP deaminase 8 310 6.1E-72 T 13-09-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 THL1_RS24960 be871905c79132725f94dab780d9ca5a 316 Hamap MF_01962 Adenine deaminase. 4 316 87.124 T 13-09-2016 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 THL1_RS24960 be871905c79132725f94dab780d9ca5a 316 PANTHER PTHR11409:SF41 1 312 2.1E-172 T 13-09-2016 THL1_RS17840 6132f263ce16a22e079d6050aee90655 270 PANTHER PTHR11941 3 268 8.0E-141 T 13-09-2016 THL1_RS17840 6132f263ce16a22e079d6050aee90655 270 Gene3D G3DSA:1.10.12.10 213 270 8.2E-30 T 13-09-2016 IPR014748 Crontonase, C-terminal THL1_RS17840 6132f263ce16a22e079d6050aee90655 270 Gene3D G3DSA:3.90.226.10 4 212 2.7E-65 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS17840 6132f263ce16a22e079d6050aee90655 270 PANTHER PTHR11941:SF43 3 268 8.0E-141 T 13-09-2016 THL1_RS17840 6132f263ce16a22e079d6050aee90655 270 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 270 2.8E-49 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS17840 6132f263ce16a22e079d6050aee90655 270 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 111 131 - T 13-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THL1_RS17840 6132f263ce16a22e079d6050aee90655 270 SUPERFAMILY SSF52096 3 269 1.39E-80 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 PANTHER PTHR24423:SF451 386 631 5.3E-127 T 13-09-2016 THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 Pfam PF02743 Cache domain 52 303 1.6E-20 T 13-09-2016 IPR033479 Double Cache domain 1 THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 Gene3D G3DSA:3.30.450.20 189 313 1.3E-4 T 13-09-2016 THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 Pfam PF00512 His Kinase A (phospho-acceptor) domain 411 474 1.6E-6 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 PRINTS PR00344 Bacterial sensor protein C-terminal signature 573 583 6.7E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 PRINTS PR00344 Bacterial sensor protein C-terminal signature 555 569 6.7E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 PRINTS PR00344 Bacterial sensor protein C-terminal signature 610 623 6.7E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 PRINTS PR00344 Bacterial sensor protein C-terminal signature 586 604 6.7E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 SMART SM00387 516 626 2.3E-25 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 Gene3D G3DSA:1.10.287.130 411 473 4.7E-4 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 PIRSF PIRSF036431 8 633 1.3E-205 T 13-09-2016 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 SMART SM00388 409 477 3.3E-5 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 517 624 2.4E-18 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 Gene3D G3DSA:3.30.450.20 113 188 9.3E-6 T 13-09-2016 THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 SUPERFAMILY SSF55874 482 624 1.57E-32 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 PANTHER PTHR24423 72 139 5.3E-127 T 13-09-2016 THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 PANTHER PTHR24423 386 631 5.3E-127 T 13-09-2016 THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 PANTHER PTHR24423:SF451 72 139 5.3E-127 T 13-09-2016 THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 SUPERFAMILY SSF103190 74 205 7.26E-17 T 13-09-2016 IPR029151 Periplasmic sensor domain-like THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 SUPERFAMILY SSF47384 406 475 1.96E-8 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS18975 da87f7dc11efcb1c1fd217fa94b0ae2a 636 Gene3D G3DSA:3.30.565.10 483 630 2.0E-32 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS26245 51d9f7ec4970cb83cf3206f54c3125b3 324 PANTHER PTHR30269 77 320 1.6E-132 T 13-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 THL1_RS26245 51d9f7ec4970cb83cf3206f54c3125b3 324 PANTHER PTHR30269:SF5 77 320 1.6E-132 T 13-09-2016 THL1_RS26245 51d9f7ec4970cb83cf3206f54c3125b3 324 Pfam PF01925 Sulfite exporter TauE/SafE 86 316 1.7E-36 T 13-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 THL1_RS23420 bded9a9341f269f5c5711fdf70580455 546 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 525 1.4E-254 T 13-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 THL1_RS23420 bded9a9341f269f5c5711fdf70580455 546 Hamap MF_00600 60 kDa chaperonin [groL]. 2 545 41.626 T 13-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 THL1_RS23420 bded9a9341f269f5c5711fdf70580455 546 SUPERFAMILY SSF48592 406 521 9.99E-76 T 13-09-2016 THL1_RS23420 bded9a9341f269f5c5711fdf70580455 546 SUPERFAMILY SSF48592 7 134 9.99E-76 T 13-09-2016 THL1_RS23420 bded9a9341f269f5c5711fdf70580455 546 PANTHER PTHR11353 2 546 1.1E-251 T 13-09-2016 THL1_RS23420 bded9a9341f269f5c5711fdf70580455 546 Gene3D G3DSA:3.50.7.10 188 366 1.2E-99 T 13-09-2016 IPR027409 GroEL-like apical domain THL1_RS23420 bded9a9341f269f5c5711fdf70580455 546 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 13-09-2016 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 THL1_RS23420 bded9a9341f269f5c5711fdf70580455 546 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 523 2.0E-93 T 13-09-2016 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 THL1_RS23420 bded9a9341f269f5c5711fdf70580455 546 Gene3D G3DSA:1.10.560.10 367 518 4.0E-39 T 13-09-2016 IPR027413 GroEL-like equatorial domain THL1_RS23420 bded9a9341f269f5c5711fdf70580455 546 SUPERFAMILY SSF54849 137 203 5.04E-24 T 13-09-2016 THL1_RS23420 bded9a9341f269f5c5711fdf70580455 546 Gene3D G3DSA:1.10.560.10 3 187 1.1E-46 T 13-09-2016 IPR027413 GroEL-like equatorial domain THL1_RS23420 bded9a9341f269f5c5711fdf70580455 546 SUPERFAMILY SSF52029 184 376 8.55E-84 T 13-09-2016 IPR027409 GroEL-like apical domain THL1_RS23420 bded9a9341f269f5c5711fdf70580455 546 PRINTS PR00298 60kDa chaperonin signature 398 419 8.2E-75 T 13-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 THL1_RS23420 bded9a9341f269f5c5711fdf70580455 546 PRINTS PR00298 60kDa chaperonin signature 83 110 8.2E-75 T 13-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 THL1_RS23420 bded9a9341f269f5c5711fdf70580455 546 PRINTS PR00298 60kDa chaperonin signature 350 375 8.2E-75 T 13-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 THL1_RS23420 bded9a9341f269f5c5711fdf70580455 546 PRINTS PR00298 60kDa chaperonin signature 27 53 8.2E-75 T 13-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 THL1_RS23420 bded9a9341f269f5c5711fdf70580455 546 PRINTS PR00298 60kDa chaperonin signature 268 291 8.2E-75 T 13-09-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 THL1_RS12480 5136e66f6a772720d546797d42fc2830 207 SUPERFAMILY SSF52833 42 196 6.73E-29 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS12480 5136e66f6a772720d546797d42fc2830 207 Pfam PF02630 SCO1/SenC 57 146 4.0E-11 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS12480 5136e66f6a772720d546797d42fc2830 207 PANTHER PTHR12151 38 163 6.9E-23 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS12480 5136e66f6a772720d546797d42fc2830 207 PANTHER PTHR12151:SF10 38 163 6.9E-23 T 13-09-2016 THL1_RS12480 5136e66f6a772720d546797d42fc2830 207 Gene3D G3DSA:3.40.30.10 11 170 9.9E-29 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS27625 decba60e5594ac8d9908b4d9fe2e8fd7 479 Pfam PF02954 Bacterial regulatory protein, Fis family 435 464 4.8E-10 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS27625 decba60e5594ac8d9908b4d9fe2e8fd7 479 Gene3D G3DSA:1.10.8.60 331 404 7.0E-20 T 13-09-2016 THL1_RS27625 decba60e5594ac8d9908b4d9fe2e8fd7 479 PANTHER PTHR32071 137 477 3.1E-135 T 13-09-2016 THL1_RS27625 decba60e5594ac8d9908b4d9fe2e8fd7 479 Pfam PF00158 Sigma-54 interaction domain 158 324 1.3E-60 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS27625 decba60e5594ac8d9908b4d9fe2e8fd7 479 Gene3D G3DSA:3.30.450.20 30 134 9.2E-14 T 13-09-2016 THL1_RS27625 decba60e5594ac8d9908b4d9fe2e8fd7 479 SUPERFAMILY SSF52540 156 394 2.8E-66 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27625 decba60e5594ac8d9908b4d9fe2e8fd7 479 SUPERFAMILY SSF46689 371 466 3.88E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS27625 decba60e5594ac8d9908b4d9fe2e8fd7 479 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 430 447 4.8E-6 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS27625 decba60e5594ac8d9908b4d9fe2e8fd7 479 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 447 467 4.8E-6 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS27625 decba60e5594ac8d9908b4d9fe2e8fd7 479 Pfam PF08448 PAS fold 37 139 1.2E-7 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS27625 decba60e5594ac8d9908b4d9fe2e8fd7 479 Gene3D G3DSA:1.10.10.60 412 467 1.0E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS27625 decba60e5594ac8d9908b4d9fe2e8fd7 479 SUPERFAMILY SSF55785 19 133 7.61E-11 T 13-09-2016 IPR000014 PAS domain THL1_RS27625 decba60e5594ac8d9908b4d9fe2e8fd7 479 Gene3D G3DSA:3.40.50.300 153 330 4.4E-55 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27625 decba60e5594ac8d9908b4d9fe2e8fd7 479 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 181 194 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS27625 decba60e5594ac8d9908b4d9fe2e8fd7 479 SMART SM00382 177 322 2.0E-11 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS27625 decba60e5594ac8d9908b4d9fe2e8fd7 479 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 244 259 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 SMART SM00490 311 411 2.0E-14 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 PANTHER PTHR18934 774 902 0.0 T 13-09-2016 THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 Pfam PF00271 Helicase conserved C-terminal domain 292 410 2.3E-11 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 SMART SM00847 471 561 3.4E-35 T 13-09-2016 IPR007502 Helicase-associated domain GO:0004386 THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 PANTHER PTHR18934:SF109 3 615 0.0 T 13-09-2016 THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 PANTHER PTHR18934:SF109 774 902 0.0 T 13-09-2016 THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 Gene3D G3DSA:3.40.50.300 72 228 1.4E-47 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 SMART SM00487 69 254 1.4E-25 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 646 1334 3.6E-276 T 13-09-2016 IPR010222 RNA helicase HrpA GO:0004004 THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 12 612 0.0 T 13-09-2016 IPR010222 RNA helicase HrpA GO:0004004 THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 SUPERFAMILY SSF52540 73 591 1.78E-104 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 Pfam PF11898 Domain of unknown function (DUF3418) 747 1333 1.8E-199 T 13-09-2016 IPR024590 RNA helicase HrpA, C-terminal THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 PANTHER PTHR18934 652 739 0.0 T 13-09-2016 THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 PANTHER PTHR18934 3 615 0.0 T 13-09-2016 THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 631 734 3.1E-20 T 13-09-2016 IPR011709 Domain of unknown function DUF1605 THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 Gene3D G3DSA:3.40.50.300 293 423 4.5E-12 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 PANTHER PTHR18934:SF109 652 739 0.0 T 13-09-2016 THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 SMART SM00382 87 247 5.0E-4 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS20215 470087c0ac2ecbebac178c21d8678953 1337 Pfam PF04408 Helicase associated domain (HA2) 474 559 5.0E-18 T 13-09-2016 IPR007502 Helicase-associated domain GO:0004386 THL1_RS27160 1442649870499463bec1504d2d0ddab2 432 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 432 223.679 T 13-09-2016 IPR010167 Amino-acid N-acetyltransferase (ArgA) GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068 THL1_RS27160 1442649870499463bec1504d2d0ddab2 432 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 4 432 9.4E-217 T 13-09-2016 IPR010167 Amino-acid N-acetyltransferase (ArgA) GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068 THL1_RS27160 1442649870499463bec1504d2d0ddab2 432 Gene3D G3DSA:3.40.1160.10 21 280 6.8E-58 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS27160 1442649870499463bec1504d2d0ddab2 432 Pfam PF00583 Acetyltransferase (GNAT) family 331 403 1.3E-7 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS27160 1442649870499463bec1504d2d0ddab2 432 SUPERFAMILY SSF55729 285 410 3.95E-20 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS27160 1442649870499463bec1504d2d0ddab2 432 Gene3D G3DSA:3.40.630.30 287 428 2.2E-37 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS27160 1442649870499463bec1504d2d0ddab2 432 PANTHER PTHR30602:SF3 1 432 4.7E-255 T 13-09-2016 THL1_RS27160 1442649870499463bec1504d2d0ddab2 432 PANTHER PTHR30602 1 432 4.7E-255 T 13-09-2016 THL1_RS27160 1442649870499463bec1504d2d0ddab2 432 SUPERFAMILY SSF53633 3 282 5.59E-62 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS27160 1442649870499463bec1504d2d0ddab2 432 PIRSF PIRSF000423 1 432 3.4E-193 T 13-09-2016 IPR010167 Amino-acid N-acetyltransferase (ArgA) GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068 THL1_RS27160 1442649870499463bec1504d2d0ddab2 432 Pfam PF00696 Amino acid kinase family 24 254 2.9E-18 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS03130 b945e9d606eefd31a4c79c436819ffdf 178 PANTHER PTHR26402 2 138 4.5E-27 T 13-09-2016 THL1_RS03130 b945e9d606eefd31a4c79c436819ffdf 178 PANTHER PTHR26402:SF515 2 138 4.5E-27 T 13-09-2016 THL1_RS03130 b945e9d606eefd31a4c79c436819ffdf 178 SUPERFAMILY SSF52172 1 147 2.28E-29 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS03130 b945e9d606eefd31a4c79c436819ffdf 178 SMART SM00448 2 114 5.0E-20 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS03130 b945e9d606eefd31a4c79c436819ffdf 178 Pfam PF00072 Response regulator receiver domain 5 114 2.9E-20 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS03130 b945e9d606eefd31a4c79c436819ffdf 178 Gene3D G3DSA:3.40.50.2300 1 135 2.3E-29 T 13-09-2016 THL1_RS22180 8ec66fe8967fc5a8f5d60b0815220f4e 122 Gene3D G3DSA:3.10.129.10 2 119 6.1E-37 T 13-09-2016 IPR029069 HotDog domain THL1_RS22180 8ec66fe8967fc5a8f5d60b0815220f4e 122 Pfam PF03061 Thioesterase superfamily 31 104 1.4E-13 T 13-09-2016 IPR006683 Thioesterase domain THL1_RS22180 8ec66fe8967fc5a8f5d60b0815220f4e 122 PANTHER PTHR12418 1 119 5.6E-52 T 13-09-2016 THL1_RS22180 8ec66fe8967fc5a8f5d60b0815220f4e 122 PANTHER PTHR12418:SF30 1 119 5.6E-52 T 13-09-2016 THL1_RS22180 8ec66fe8967fc5a8f5d60b0815220f4e 122 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 2 117 1.3E-14 T 13-09-2016 IPR003736 Phenylacetic acid degradation-related domain THL1_RS22180 8ec66fe8967fc5a8f5d60b0815220f4e 122 SUPERFAMILY SSF54637 3 118 1.93E-25 T 13-09-2016 IPR029069 HotDog domain THL1_RS14430 a2a325bb49b9edc2c54c0eff9f7d502b 327 SUPERFAMILY SSF51735 118 286 7.96E-40 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS14430 a2a325bb49b9edc2c54c0eff9f7d502b 327 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 88 1.3E-4 T 13-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THL1_RS14430 a2a325bb49b9edc2c54c0eff9f7d502b 327 SUPERFAMILY SSF50129 3 145 1.89E-43 T 13-09-2016 IPR011032 GroES-like THL1_RS14430 a2a325bb49b9edc2c54c0eff9f7d502b 327 Gene3D G3DSA:3.40.50.720 126 292 1.5E-74 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS14430 a2a325bb49b9edc2c54c0eff9f7d502b 327 Pfam PF00107 Zinc-binding dehydrogenase 159 274 8.4E-14 T 13-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THL1_RS14430 a2a325bb49b9edc2c54c0eff9f7d502b 327 SMART SM00829 13 323 6.1E-5 T 13-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THL1_RS14430 a2a325bb49b9edc2c54c0eff9f7d502b 327 PANTHER PTHR11695:SF13 16 326 2.0E-148 T 13-09-2016 IPR014188 Acrylyl-CoA reductase AcuI THL1_RS14430 a2a325bb49b9edc2c54c0eff9f7d502b 327 PANTHER PTHR11695 16 326 2.0E-148 T 13-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 THL1_RS14430 a2a325bb49b9edc2c54c0eff9f7d502b 327 Gene3D G3DSA:3.90.180.10 16 88 2.7E-8 T 13-09-2016 IPR011032 GroES-like THL1_RS14430 a2a325bb49b9edc2c54c0eff9f7d502b 327 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 4 325 8.5E-135 T 13-09-2016 IPR014188 Acrylyl-CoA reductase AcuI THL1_RS12370 8f06bd869db68b7b5276f7aa3a667fd5 87 PANTHER PTHR11544:SF52 1 81 3.3E-43 T 13-09-2016 THL1_RS12370 8f06bd869db68b7b5276f7aa3a667fd5 87 PANTHER PTHR11544 1 81 3.3E-43 T 13-09-2016 THL1_RS12370 8f06bd869db68b7b5276f7aa3a667fd5 87 Gene3D G3DSA:2.40.50.140 1 65 1.0E-27 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS12370 8f06bd869db68b7b5276f7aa3a667fd5 87 SUPERFAMILY SSF50249 1 66 6.12E-23 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS12370 8f06bd869db68b7b5276f7aa3a667fd5 87 PIRSF PIRSF002599 1 85 1.4E-22 T 13-09-2016 IPR012156 Cold shock, CspA GO:0003676 THL1_RS12370 8f06bd869db68b7b5276f7aa3a667fd5 87 SMART SM00357 3 67 1.3E-25 T 13-09-2016 IPR011129 Cold shock protein GO:0003676 THL1_RS12370 8f06bd869db68b7b5276f7aa3a667fd5 87 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 13-09-2016 IPR019844 Cold-shock conserved site THL1_RS12370 8f06bd869db68b7b5276f7aa3a667fd5 87 PRINTS PR00050 Cold shock protein signature 4 19 5.6E-16 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS12370 8f06bd869db68b7b5276f7aa3a667fd5 87 PRINTS PR00050 Cold shock protein signature 25 34 5.6E-16 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS12370 8f06bd869db68b7b5276f7aa3a667fd5 87 PRINTS PR00050 Cold shock protein signature 40 58 5.6E-16 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS12370 8f06bd869db68b7b5276f7aa3a667fd5 87 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 3.1E-27 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS12370 8f06bd869db68b7b5276f7aa3a667fd5 87 TIGRFAM TIGR02381 cspD: cold shock domain protein CspD 1 67 5.1E-38 T 13-09-2016 IPR012751 CspD, cold shock GO:0003676|GO:0005737|GO:0006355|GO:0006950 THL1_RS13260 6e56b40bb903d15f6e4c6414c373a25a 504 SUPERFAMILY SSF56954 32 484 1.44E-91 T 13-09-2016 THL1_RS13260 6e56b40bb903d15f6e4c6414c373a25a 504 Gene3D G3DSA:1.20.1600.10 72 484 8.8E-94 T 13-09-2016 THL1_RS13260 6e56b40bb903d15f6e4c6414c373a25a 504 PANTHER PTHR30203 15 501 4.6E-92 T 13-09-2016 THL1_RS13260 6e56b40bb903d15f6e4c6414c373a25a 504 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 38 482 5.6E-83 T 13-09-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 THL1_RS13260 6e56b40bb903d15f6e4c6414c373a25a 504 Pfam PF02321 Outer membrane efflux protein 83 272 5.3E-30 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS13260 6e56b40bb903d15f6e4c6414c373a25a 504 Pfam PF02321 Outer membrane efflux protein 300 480 5.4E-18 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS13260 6e56b40bb903d15f6e4c6414c373a25a 504 PANTHER PTHR30203:SF3 15 501 4.6E-92 T 13-09-2016 THL1_RS14435 d59b0fd5b88d63b9c0200d306ee67659 210 Gene3D G3DSA:1.10.357.10 72 208 1.4E-25 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS14435 d59b0fd5b88d63b9c0200d306ee67659 210 PANTHER PTHR30055 10 200 1.4E-50 T 13-09-2016 THL1_RS14435 d59b0fd5b88d63b9c0200d306ee67659 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 2.1E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS14435 d59b0fd5b88d63b9c0200d306ee67659 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 2.1E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS14435 d59b0fd5b88d63b9c0200d306ee67659 210 SUPERFAMILY SSF48498 95 208 1.4E-27 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS14435 d59b0fd5b88d63b9c0200d306ee67659 210 PANTHER PTHR30055:SF20 10 200 1.4E-50 T 13-09-2016 THL1_RS14435 d59b0fd5b88d63b9c0200d306ee67659 210 Gene3D G3DSA:1.10.10.60 16 71 8.0E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS14435 d59b0fd5b88d63b9c0200d306ee67659 210 Pfam PF16925 Bacterial transcriptional repressor C-terminal 95 208 2.0E-48 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS14435 d59b0fd5b88d63b9c0200d306ee67659 210 SUPERFAMILY SSF46689 14 87 3.9E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS14435 d59b0fd5b88d63b9c0200d306ee67659 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 69 2.9E-11 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 273 288 0.0071 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 145 161 0.012 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 128 144 0.0014 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 107 117 1.2 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 256 271 0.0078 T 13-09-2016 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 SUPERFAMILY SSF51120 256 359 3.4E-19 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 133 151 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 SUPERFAMILY SSF51120 105 246 2.09E-22 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 260 278 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 Pfam PF06594 Haemolysin-type calcium binding protein related domain 331 359 1.1E-4 T 13-09-2016 IPR010566 Haemolysin-type calcium binding-related THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 Pfam PF06594 Haemolysin-type calcium binding protein related domain 57 97 1.1E-14 T 13-09-2016 IPR010566 Haemolysin-type calcium binding-related THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 Pfam PF06594 Haemolysin-type calcium binding protein related domain 208 248 1.4E-14 T 13-09-2016 IPR010566 Haemolysin-type calcium binding-related THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 142 160 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 Gene3D G3DSA:2.150.10.10 105 249 4.1E-27 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 Gene3D G3DSA:2.150.10.10 256 361 1.1E-21 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 Gene3D G3DSA:2.150.10.10 1 98 6.5E-13 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 SUPERFAMILY SSF51120 1 95 1.96E-9 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 PRINTS PR00313 NodO calcium binding signature 273 281 6.1E-12 T 13-09-2016 THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 PRINTS PR00313 NodO calcium binding signature 282 291 6.1E-12 T 13-09-2016 THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 PRINTS PR00313 NodO calcium binding signature 146 154 6.1E-12 T 13-09-2016 THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 PRINTS PR00313 NodO calcium binding signature 125 136 6.1E-12 T 13-09-2016 THL1_RS16615 77f8b2197ddabd40d054047323e3b479 408 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 269 287 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS01875 d4bd0286804b46d7e86313e70dfa45d1 833 PANTHER PTHR30451 1 833 3.3E-269 T 13-09-2016 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 THL1_RS01875 d4bd0286804b46d7e86313e70dfa45d1 833 Pfam PF00577 Outer membrane usher protein 200 745 4.0E-163 T 13-09-2016 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 THL1_RS01875 d4bd0286804b46d7e86313e70dfa45d1 833 Pfam PF13953 PapC C-terminal domain 757 817 1.7E-11 T 13-09-2016 IPR025949 PapC-like, C-terminal domain THL1_RS01875 d4bd0286804b46d7e86313e70dfa45d1 833 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 310 320 - T 13-09-2016 IPR018030 Fimbrial membrane usher, conserved site THL1_RS01875 d4bd0286804b46d7e86313e70dfa45d1 833 Pfam PF13954 PapC N-terminal domain 37 183 4.7E-41 T 13-09-2016 IPR025885 PapC, N-terminal domain GO:0005515 THL1_RS01875 d4bd0286804b46d7e86313e70dfa45d1 833 PANTHER PTHR30451:SF2 1 833 3.3E-269 T 13-09-2016 THL1_RS01875 d4bd0286804b46d7e86313e70dfa45d1 833 SUPERFAMILY SSF141729 59 175 4.58E-28 T 13-09-2016 THL1_RS16105 1c61c7dd98abfc981274b986f2342bbd 153 Pfam PF05926 Phage head completion protein (GPL) 15 153 6.2E-51 T 13-09-2016 IPR009225 Bacteriophage head completion protein GpL GO:0019069 THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 Gene3D G3DSA:3.40.50.300 4 214 1.3E-65 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-09-2016 IPR031157 Tr-type G domain, conserved site THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 Gene3D G3DSA:2.40.30.10 215 301 6.6E-36 T 13-09-2016 THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 Pfam PF03144 Elongation factor Tu domain 2 228 296 2.5E-15 T 13-09-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 Pfam PF03143 Elongation factor Tu C-terminal domain 301 395 1.0E-33 T 13-09-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 Gene3D G3DSA:2.40.30.10 303 395 8.5E-47 T 13-09-2016 THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 396 1.9E-226 T 13-09-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 SUPERFAMILY SSF50447 208 304 1.79E-29 T 13-09-2016 IPR009000 Translation protein, beta-barrel domain THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 1.1E-14 T 13-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 59.563 T 13-09-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 204 6.9E-57 T 13-09-2016 THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.9E-24 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 PRINTS PR00315 GTP-binding elongation factor signature 131 140 1.9E-24 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.9E-24 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.9E-24 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.9E-24 T 13-09-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 SUPERFAMILY SSF52540 6 222 6.64E-58 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 PANTHER PTHR23115:SF151 1 395 3.2E-274 T 13-09-2016 THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 SUPERFAMILY SSF50465 301 396 3.74E-36 T 13-09-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal THL1_RS03515 b499f88f354f810669c01f9e935e7784 397 PANTHER PTHR23115 1 395 3.2E-274 T 13-09-2016 THL1_RS17270 d5340a509280229cb99557114b51c5c1 341 Gene3D G3DSA:1.10.10.60 282 330 1.2E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17270 d5340a509280229cb99557114b51c5c1 341 SUPERFAMILY SSF46689 279 330 2.64E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17270 d5340a509280229cb99557114b51c5c1 341 SMART SM00342 243 325 4.1E-19 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS17270 d5340a509280229cb99557114b51c5c1 341 Pfam PF12833 Helix-turn-helix domain 249 326 5.1E-16 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS17270 d5340a509280229cb99557114b51c5c1 341 PANTHER PTHR11019:SF52 206 333 1.2E-19 T 13-09-2016 THL1_RS17270 d5340a509280229cb99557114b51c5c1 341 PANTHER PTHR11019:SF52 83 94 1.2E-19 T 13-09-2016 THL1_RS17270 d5340a509280229cb99557114b51c5c1 341 PANTHER PTHR11019 206 333 1.2E-19 T 13-09-2016 THL1_RS17270 d5340a509280229cb99557114b51c5c1 341 PANTHER PTHR11019 83 94 1.2E-19 T 13-09-2016 THL1_RS17270 d5340a509280229cb99557114b51c5c1 341 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 21 201 6.3E-39 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS11695 d9212a3229edbe6d32962972eff7f34f 662 PANTHER PTHR33490:SF4 7 656 4.2E-123 T 13-09-2016 THL1_RS11695 d9212a3229edbe6d32962972eff7f34f 662 PANTHER PTHR33490 7 656 4.2E-123 T 13-09-2016 THL1_RS11695 d9212a3229edbe6d32962972eff7f34f 662 SMART SM00460 399 470 2.3E-25 T 13-09-2016 IPR002931 Transglutaminase-like THL1_RS11695 d9212a3229edbe6d32962972eff7f34f 662 Pfam PF13559 Domain of unknown function (DUF4129) 585 642 5.6E-9 T 13-09-2016 IPR025403 Domain of unknown function DUF4129 THL1_RS11695 d9212a3229edbe6d32962972eff7f34f 662 Pfam PF11992 Domain of unknown function (DUF3488) 12 324 1.6E-103 T 13-09-2016 IPR021878 Protein of unknown function DUF3488 THL1_RS11695 d9212a3229edbe6d32962972eff7f34f 662 Gene3D G3DSA:3.90.260.10 288 595 7.2E-54 T 13-09-2016 IPR002931 Transglutaminase-like THL1_RS11695 d9212a3229edbe6d32962972eff7f34f 662 SUPERFAMILY SSF54001 273 603 1.54E-70 T 13-09-2016 THL1_RS11695 d9212a3229edbe6d32962972eff7f34f 662 Pfam PF01841 Transglutaminase-like superfamily 352 468 3.9E-24 T 13-09-2016 IPR002931 Transglutaminase-like THL1_RS13710 8c934f89f9d4abb1f4a498fecf2899cf 307 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 280 2.4E-82 T 13-09-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 THL1_RS13710 8c934f89f9d4abb1f4a498fecf2899cf 307 SUPERFAMILY SSF53213 12 280 4.05E-48 T 13-09-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 THL1_RS13710 8c934f89f9d4abb1f4a498fecf2899cf 307 TIGRFAM TIGR02298 HpaD_Fe: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 1 282 1.3E-138 T 13-09-2016 IPR011984 3,4-dihydroxyphenylacetate 2,3-dioxygenase HpaD-Fe KEGG: 00350+1.13.11.15|UniPathway: UPA00208 THL1_RS13710 8c934f89f9d4abb1f4a498fecf2899cf 307 Gene3D G3DSA:3.40.830.10 5 268 1.2E-23 T 13-09-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 THL1_RS02815 c19ac09bebbbf47b4da0814d4556cfa5 416 PANTHER PTHR13847:SF191 2 396 5.5E-134 T 13-09-2016 THL1_RS02815 c19ac09bebbbf47b4da0814d4556cfa5 416 SUPERFAMILY SSF51905 2 283 1.99E-51 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS02815 c19ac09bebbbf47b4da0814d4556cfa5 416 Gene3D G3DSA:3.30.9.10 226 249 6.3E-10 T 13-09-2016 THL1_RS02815 c19ac09bebbbf47b4da0814d4556cfa5 416 Gene3D G3DSA:3.30.9.10 86 137 6.3E-10 T 13-09-2016 THL1_RS02815 c19ac09bebbbf47b4da0814d4556cfa5 416 Pfam PF01266 FAD dependent oxidoreductase 3 390 2.0E-72 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS02815 c19ac09bebbbf47b4da0814d4556cfa5 416 PANTHER PTHR13847 2 396 5.5E-134 T 13-09-2016 THL1_RS02815 c19ac09bebbbf47b4da0814d4556cfa5 416 Gene3D G3DSA:3.50.50.60 2 84 1.0E-34 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS02815 c19ac09bebbbf47b4da0814d4556cfa5 416 Gene3D G3DSA:3.50.50.60 138 215 1.0E-34 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS25630 5be25267cf867a0f5683574ed8cf2131 211 PANTHER PTHR30055 1 204 7.6E-86 T 13-09-2016 THL1_RS25630 5be25267cf867a0f5683574ed8cf2131 211 SUPERFAMILY SSF46689 2 74 7.18E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS25630 5be25267cf867a0f5683574ed8cf2131 211 PANTHER PTHR30055:SF39 1 204 7.6E-86 T 13-09-2016 THL1_RS25630 5be25267cf867a0f5683574ed8cf2131 211 Gene3D G3DSA:1.10.357.10 1 176 2.3E-30 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS25630 5be25267cf867a0f5683574ed8cf2131 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 3.6E-7 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS24225 aee379e9b7cd3b7c147beba592ea8331 90 PANTHER PTHR36121:SF1 1 77 6.5E-28 T 13-09-2016 THL1_RS24225 aee379e9b7cd3b7c147beba592ea8331 90 PANTHER PTHR36121 1 77 6.5E-28 T 13-09-2016 THL1_RS24225 aee379e9b7cd3b7c147beba592ea8331 90 Gene3D G3DSA:1.10.150.20 2 83 2.8E-26 T 13-09-2016 THL1_RS24225 aee379e9b7cd3b7c147beba592ea8331 90 Pfam PF04994 TfoX C-terminal domain 1 80 2.2E-28 T 13-09-2016 IPR007077 TfoX, C-terminal THL1_RS21130 e0a89868738d6c14539abdecdb102c38 167 Pfam PF04355 SmpA / OmlA family 113 164 2.9E-5 T 13-09-2016 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 THL1_RS21130 e0a89868738d6c14539abdecdb102c38 167 Pfam PF13511 Domain of unknown function (DUF4124) 16 57 1.1E-8 T 13-09-2016 IPR025392 Domain of unknown function DUF4124 THL1_RS07905 fac8c25913d136d1f1f886982eb87ee7 118 PANTHER PTHR11803 10 114 7.7E-19 T 13-09-2016 IPR006175 YjgF/YER057c/UK114 family THL1_RS07905 fac8c25913d136d1f1f886982eb87ee7 118 Pfam PF01042 Endoribonuclease L-PSP 11 108 2.3E-13 T 13-09-2016 IPR006175 YjgF/YER057c/UK114 family THL1_RS07905 fac8c25913d136d1f1f886982eb87ee7 118 Gene3D G3DSA:3.30.1330.40 6 112 3.8E-17 T 13-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THL1_RS07905 fac8c25913d136d1f1f886982eb87ee7 118 SUPERFAMILY SSF55298 4 111 1.49E-21 T 13-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THL1_RS10820 bdf7642c4a31d2b37ec1c6b68ce6be3b 290 PIRSF PIRSF000103 1 290 1.6E-68 T 13-09-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 THL1_RS10820 bdf7642c4a31d2b37ec1c6b68ce6be3b 290 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 284 5.3E-34 T 13-09-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 THL1_RS10820 bdf7642c4a31d2b37ec1c6b68ce6be3b 290 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 163 4.2E-45 T 13-09-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 THL1_RS10820 bdf7642c4a31d2b37ec1c6b68ce6be3b 290 PANTHER PTHR22981:SF49 1 288 1.0E-147 T 13-09-2016 THL1_RS10820 bdf7642c4a31d2b37ec1c6b68ce6be3b 290 Gene3D G3DSA:3.40.50.720 1 167 1.3E-49 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10820 bdf7642c4a31d2b37ec1c6b68ce6be3b 290 SUPERFAMILY SSF51735 3 165 7.3E-48 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10820 bdf7642c4a31d2b37ec1c6b68ce6be3b 290 Gene3D G3DSA:1.10.1040.10 168 288 1.1E-40 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS10820 bdf7642c4a31d2b37ec1c6b68ce6be3b 290 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 13-09-2016 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 THL1_RS10820 bdf7642c4a31d2b37ec1c6b68ce6be3b 290 SUPERFAMILY SSF48179 164 288 1.59E-40 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS10820 bdf7642c4a31d2b37ec1c6b68ce6be3b 290 PANTHER PTHR22981 1 288 1.0E-147 T 13-09-2016 THL1_RS22610 a81ce6afef47b675634c38bde0c6e333 396 SUPERFAMILY SSF51735 3 153 4.44E-45 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS22610 a81ce6afef47b675634c38bde0c6e333 396 PANTHER PTHR30525 2 391 7.9E-217 T 13-09-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS22610 a81ce6afef47b675634c38bde0c6e333 396 Gene3D G3DSA:3.40.50.720 2 153 6.2E-52 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS22610 a81ce6afef47b675634c38bde0c6e333 396 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 7 135 9.5E-44 T 13-09-2016 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS22610 a81ce6afef47b675634c38bde0c6e333 396 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 149 237 1.9E-37 T 13-09-2016 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS22610 a81ce6afef47b675634c38bde0c6e333 396 PIRSF PIRSF006205 4 396 5.9E-149 T 13-09-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS22610 a81ce6afef47b675634c38bde0c6e333 396 Gene3D G3DSA:1.10.1740.10 311 391 1.6E-29 T 13-09-2016 THL1_RS22610 a81ce6afef47b675634c38bde0c6e333 396 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 7 390 47.083 T 13-09-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS22610 a81ce6afef47b675634c38bde0c6e333 396 SUPERFAMILY SSF55347 129 272 1.86E-60 T 13-09-2016 THL1_RS22610 a81ce6afef47b675634c38bde0c6e333 396 SUPERFAMILY SSF69055 300 391 2.09E-29 T 13-09-2016 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS22610 a81ce6afef47b675634c38bde0c6e333 396 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 6 389 1.1E-155 T 13-09-2016 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS22610 a81ce6afef47b675634c38bde0c6e333 396 Pfam PF13288 DXP reductoisomerase C-terminal domain 269 385 7.3E-43 T 13-09-2016 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS11890 44037c7c3a287abccead0dd84436c2dc 249 Pfam PF08241 Methyltransferase domain 42 130 6.5E-17 T 13-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 THL1_RS11890 44037c7c3a287abccead0dd84436c2dc 249 SUPERFAMILY SSF53335 13 199 3.94E-25 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS11890 44037c7c3a287abccead0dd84436c2dc 249 Gene3D G3DSA:3.40.50.150 20 243 6.0E-28 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS11890 44037c7c3a287abccead0dd84436c2dc 249 PANTHER PTHR10108:SF730 4 231 9.5E-44 T 13-09-2016 THL1_RS11890 44037c7c3a287abccead0dd84436c2dc 249 PANTHER PTHR10108 4 231 9.5E-44 T 13-09-2016 THL1_RS21375 83ef730053a292ef7e4af795539ebd59 421 PANTHER PTHR34596 1 421 2.6E-172 T 13-09-2016 THL1_RS21375 83ef730053a292ef7e4af795539ebd59 421 Pfam PF03573 outer membrane porin, OprD family 31 419 6.5E-155 T 13-09-2016 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 THL1_RS21375 83ef730053a292ef7e4af795539ebd59 421 Gene3D G3DSA:2.40.160.10 35 421 6.9E-148 T 13-09-2016 IPR023614 Porin domain THL1_RS11700 a01c5c7e55606f2bb703e233505f9ef4 253 Pfam PF05235 CHAD domain 19 216 1.0E-26 T 13-09-2016 IPR007899 CHAD domain THL1_RS11700 a01c5c7e55606f2bb703e233505f9ef4 253 SMART SM00880 11 252 3.7E-33 T 13-09-2016 IPR007899 CHAD domain THL1_RS05965 ff17f6d3680f646808d66c36f7845073 143 Gene3D G3DSA:3.30.70.141 1 139 3.1E-61 T 13-09-2016 THL1_RS05965 ff17f6d3680f646808d66c36f7845073 143 PANTHER PTHR11349 1 139 1.2E-74 T 13-09-2016 THL1_RS05965 ff17f6d3680f646808d66c36f7845073 143 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 13-09-2016 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS05965 ff17f6d3680f646808d66c36f7845073 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 2.9E-41 T 13-09-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS05965 ff17f6d3680f646808d66c36f7845073 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 2.9E-41 T 13-09-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS05965 ff17f6d3680f646808d66c36f7845073 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 2.9E-41 T 13-09-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS05965 ff17f6d3680f646808d66c36f7845073 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 2.9E-41 T 13-09-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS05965 ff17f6d3680f646808d66c36f7845073 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 2.9E-41 T 13-09-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS05965 ff17f6d3680f646808d66c36f7845073 143 SUPERFAMILY SSF54919 1 140 1.17E-58 T 13-09-2016 THL1_RS05965 ff17f6d3680f646808d66c36f7845073 143 SMART SM00562 3 140 7.0E-90 T 13-09-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS05965 ff17f6d3680f646808d66c36f7845073 143 Pfam PF00334 Nucleoside diphosphate kinase 4 137 4.4E-58 T 13-09-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS05965 ff17f6d3680f646808d66c36f7845073 143 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 36.344 T 13-09-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS17855 6d4d441675827f6b33d4675be5183f82 751 Gene3D G3DSA:3.40.640.10 149 452 1.7E-112 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS17855 6d4d441675827f6b33d4675be5183f82 751 PANTHER PTHR11751:SF406 544 667 6.1E-204 T 13-09-2016 THL1_RS17855 6d4d441675827f6b33d4675be5183f82 751 SUPERFAMILY SSF53383 149 599 2.18E-114 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS17855 6d4d441675827f6b33d4675be5183f82 751 PANTHER PTHR11751 150 491 6.1E-204 T 13-09-2016 THL1_RS17855 6d4d441675827f6b33d4675be5183f82 751 PANTHER PTHR11751:SF406 519 527 6.1E-204 T 13-09-2016 THL1_RS17855 6d4d441675827f6b33d4675be5183f82 751 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 149 582 6.6E-159 T 13-09-2016 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 THL1_RS17855 6d4d441675827f6b33d4675be5183f82 751 PIRSF PIRSF009393 3 751 7.9E-285 T 13-09-2016 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 THL1_RS17855 6d4d441675827f6b33d4675be5183f82 751 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 22 143 1.1E-23 T 13-09-2016 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 THL1_RS17855 6d4d441675827f6b33d4675be5183f82 751 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 607 737 1.1E-49 T 13-09-2016 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 THL1_RS17855 6d4d441675827f6b33d4675be5183f82 751 PANTHER PTHR11751 519 527 6.1E-204 T 13-09-2016 THL1_RS17855 6d4d441675827f6b33d4675be5183f82 751 PANTHER PTHR11751:SF406 150 491 6.1E-204 T 13-09-2016 THL1_RS17855 6d4d441675827f6b33d4675be5183f82 751 Gene3D G3DSA:3.90.1150.10 455 624 5.1E-62 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS17855 6d4d441675827f6b33d4675be5183f82 751 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 388 402 - T 13-09-2016 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 THL1_RS17855 6d4d441675827f6b33d4675be5183f82 751 SUPERFAMILY SSF55904 602 751 3.66E-42 T 13-09-2016 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 THL1_RS17855 6d4d441675827f6b33d4675be5183f82 751 PANTHER PTHR11751 544 667 6.1E-204 T 13-09-2016 THL1_RS17855 6d4d441675827f6b33d4675be5183f82 751 Gene3D G3DSA:3.90.100.10 625 744 1.2E-34 T 13-09-2016 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 THL1_RS12935 6bce944e467e0ef29f53d966594a4574 118 Gene3D G3DSA:1.10.10.10 8 91 7.0E-29 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12935 6bce944e467e0ef29f53d966594a4574 118 SUPERFAMILY SSF46785 6 88 1.03E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12935 6bce944e467e0ef29f53d966594a4574 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 31 42 1.3E-22 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS12935 6bce944e467e0ef29f53d966594a4574 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 1.3E-22 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS12935 6bce944e467e0ef29f53d966594a4574 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 1.3E-22 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS12935 6bce944e467e0ef29f53d966594a4574 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 1.3E-22 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS12935 6bce944e467e0ef29f53d966594a4574 118 SMART SM00418 9 91 4.7E-30 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS12935 6bce944e467e0ef29f53d966594a4574 118 PANTHER PTHR33154 10 103 9.3E-24 T 13-09-2016 THL1_RS12935 6bce944e467e0ef29f53d966594a4574 118 Pfam PF01022 Bacterial regulatory protein, arsR family 16 61 3.4E-14 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS07750 9423b6d88b44a603e06742e3ef6ecca3 365 SUPERFAMILY SSF111369 53 277 4.05E-19 T 13-09-2016 THL1_RS07750 9423b6d88b44a603e06742e3ef6ecca3 365 Gene3D G3DSA:2.40.50.100 67 95 2.0E-12 T 13-09-2016 THL1_RS07750 9423b6d88b44a603e06742e3ef6ecca3 365 Gene3D G3DSA:2.40.50.100 170 201 2.0E-12 T 13-09-2016 THL1_RS07750 9423b6d88b44a603e06742e3ef6ecca3 365 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 355 2.1E-60 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS07750 9423b6d88b44a603e06742e3ef6ecca3 365 PANTHER PTHR30469 1 365 1.9E-56 T 13-09-2016 THL1_RS07750 9423b6d88b44a603e06742e3ef6ecca3 365 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 61 268 9.4E-13 T 13-09-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THL1_RS22550 406e6a50e27062af609e95719e9f91f0 543 SUPERFAMILY SSF52540 1 267 1.72E-121 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22550 406e6a50e27062af609e95719e9f91f0 543 Pfam PF06418 CTP synthase N-terminus 3 265 4.2E-125 T 13-09-2016 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 THL1_RS22550 406e6a50e27062af609e95719e9f91f0 543 PANTHER PTHR11550 1 541 0.0 T 13-09-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 THL1_RS22550 406e6a50e27062af609e95719e9f91f0 543 TIGRFAM TIGR00337 PyrG: CTP synthase 2 534 1.2E-251 T 13-09-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 THL1_RS22550 406e6a50e27062af609e95719e9f91f0 543 Pfam PF00117 Glutamine amidotransferase class-I 300 533 5.2E-58 T 13-09-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 THL1_RS22550 406e6a50e27062af609e95719e9f91f0 543 Gene3D G3DSA:3.40.50.880 286 540 1.2E-97 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS22550 406e6a50e27062af609e95719e9f91f0 543 Gene3D G3DSA:3.40.50.300 1 280 1.8E-132 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22550 406e6a50e27062af609e95719e9f91f0 543 SUPERFAMILY SSF52317 288 540 2.52E-88 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS22550 406e6a50e27062af609e95719e9f91f0 543 Hamap MF_01227 CTP synthase [pyrG]. 2 539 51.147 T 13-09-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 THL1_RS16785 514ca554a6db5844ec44429c583a0343 393 Pfam PF00175 Oxidoreductase NAD-binding domain 264 367 1.2E-10 T 13-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THL1_RS16785 514ca554a6db5844ec44429c583a0343 393 Gene3D G3DSA:2.40.30.10 152 255 2.9E-31 T 13-09-2016 THL1_RS16785 514ca554a6db5844ec44429c583a0343 393 PRINTS PR00409 Phthalate dioxygenase reductase family signature 227 241 1.3E-9 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS16785 514ca554a6db5844ec44429c583a0343 393 PRINTS PR00409 Phthalate dioxygenase reductase family signature 241 255 1.3E-9 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS16785 514ca554a6db5844ec44429c583a0343 393 PRINTS PR00409 Phthalate dioxygenase reductase family signature 263 282 1.3E-9 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS16785 514ca554a6db5844ec44429c583a0343 393 PRINTS PR00409 Phthalate dioxygenase reductase family signature 180 190 1.3E-9 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS16785 514ca554a6db5844ec44429c583a0343 393 SUPERFAMILY SSF63380 151 253 1.51E-28 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS16785 514ca554a6db5844ec44429c583a0343 393 PANTHER PTHR22924 1 391 3.0E-122 T 13-09-2016 THL1_RS16785 514ca554a6db5844ec44429c583a0343 393 SUPERFAMILY SSF46458 1 142 3.99E-36 T 13-09-2016 IPR009050 Globin-like THL1_RS16785 514ca554a6db5844ec44429c583a0343 393 PANTHER PTHR22924:SF49 1 391 3.0E-122 T 13-09-2016 THL1_RS16785 514ca554a6db5844ec44429c583a0343 393 Pfam PF00042 Globin 6 103 1.0E-6 T 13-09-2016 IPR000971 Globin GO:0019825|GO:0020037 THL1_RS16785 514ca554a6db5844ec44429c583a0343 393 Gene3D G3DSA:3.40.50.80 258 389 2.2E-30 T 13-09-2016 THL1_RS16785 514ca554a6db5844ec44429c583a0343 393 SUPERFAMILY SSF52343 256 388 2.88E-33 T 13-09-2016 THL1_RS16785 514ca554a6db5844ec44429c583a0343 393 Pfam PF00970 Oxidoreductase FAD-binding domain 159 253 1.7E-13 T 13-09-2016 IPR008333 Oxidoreductase, FAD-binding domain THL1_RS16785 514ca554a6db5844ec44429c583a0343 393 Gene3D G3DSA:1.10.490.10 3 143 3.8E-48 T 13-09-2016 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 THL1_RS02070 c2be0323e50f4a12f13ccb6fbf50b5ae 299 Pfam PF01553 Acyltransferase 73 226 4.2E-14 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS02070 c2be0323e50f4a12f13ccb6fbf50b5ae 299 SMART SM00563 85 227 8.1E-21 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS02070 c2be0323e50f4a12f13ccb6fbf50b5ae 299 PANTHER PTHR10983:SF15 1 292 1.4E-133 T 13-09-2016 THL1_RS02070 c2be0323e50f4a12f13ccb6fbf50b5ae 299 PANTHER PTHR10983 1 292 1.4E-133 T 13-09-2016 THL1_RS02070 c2be0323e50f4a12f13ccb6fbf50b5ae 299 SUPERFAMILY SSF69593 13 290 2.35E-49 T 13-09-2016 THL1_RS19180 aab5babb4c80c561e90201064356fc15 743 ProSitePatterns PS00885 EPSP synthase signature 2. 648 666 - T 13-09-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS19180 aab5babb4c80c561e90201064356fc15 743 PANTHER PTHR21090:SF5 314 737 7.6E-183 T 13-09-2016 THL1_RS19180 aab5babb4c80c561e90201064356fc15 743 Pfam PF02153 Prephenate dehydrogenase 26 281 1.3E-74 T 13-09-2016 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 THL1_RS19180 aab5babb4c80c561e90201064356fc15 743 ProSitePatterns PS00104 EPSP synthase signature 1. 396 410 - T 13-09-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS19180 aab5babb4c80c561e90201064356fc15 743 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 321 734 4.9E-127 T 13-09-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS19180 aab5babb4c80c561e90201064356fc15 743 Gene3D G3DSA:3.65.10.10 538 735 8.7E-53 T 13-09-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 THL1_RS19180 aab5babb4c80c561e90201064356fc15 743 PANTHER PTHR21090 314 737 7.6E-183 T 13-09-2016 THL1_RS19180 aab5babb4c80c561e90201064356fc15 743 Gene3D G3DSA:3.40.50.720 11 189 1.7E-39 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS19180 aab5babb4c80c561e90201064356fc15 743 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 317 736 33.663 T 13-09-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS19180 aab5babb4c80c561e90201064356fc15 743 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 314 727 3.1E-119 T 13-09-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 THL1_RS19180 aab5babb4c80c561e90201064356fc15 743 Gene3D G3DSA:3.65.10.10 329 537 2.6E-63 T 13-09-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 THL1_RS19180 aab5babb4c80c561e90201064356fc15 743 SUPERFAMILY SSF55205 312 735 6.54E-132 T 13-09-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 THL1_RS19180 aab5babb4c80c561e90201064356fc15 743 SUPERFAMILY SSF48179 183 291 3.17E-34 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS19180 aab5babb4c80c561e90201064356fc15 743 SUPERFAMILY SSF51735 12 179 1.05E-47 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS19120 97afa90b49ae48963bb1d2d8b38acf46 362 Gene3D G3DSA:3.40.190.10 134 310 4.4E-62 T 13-09-2016 THL1_RS19120 97afa90b49ae48963bb1d2d8b38acf46 362 Gene3D G3DSA:3.40.190.10 34 133 4.2E-12 T 13-09-2016 THL1_RS19120 97afa90b49ae48963bb1d2d8b38acf46 362 SUPERFAMILY SSF53850 23 361 2.64E-90 T 13-09-2016 THL1_RS19120 97afa90b49ae48963bb1d2d8b38acf46 362 Pfam PF13416 Bacterial extracellular solute-binding protein 39 327 2.1E-29 T 13-09-2016 THL1_RS19120 97afa90b49ae48963bb1d2d8b38acf46 362 PANTHER PTHR30222:SF11 16 361 1.6E-173 T 13-09-2016 THL1_RS19120 97afa90b49ae48963bb1d2d8b38acf46 362 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 28 44 1.1E-57 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19120 97afa90b49ae48963bb1d2d8b38acf46 362 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 87 100 1.1E-57 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19120 97afa90b49ae48963bb1d2d8b38acf46 362 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 71 85 1.1E-57 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19120 97afa90b49ae48963bb1d2d8b38acf46 362 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 261 280 1.1E-57 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19120 97afa90b49ae48963bb1d2d8b38acf46 362 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 306 332 1.1E-57 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19120 97afa90b49ae48963bb1d2d8b38acf46 362 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 211 230 1.1E-57 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19120 97afa90b49ae48963bb1d2d8b38acf46 362 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 44 65 1.1E-57 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19120 97afa90b49ae48963bb1d2d8b38acf46 362 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 120 136 1.1E-57 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19120 97afa90b49ae48963bb1d2d8b38acf46 362 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 174 193 1.1E-57 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19120 97afa90b49ae48963bb1d2d8b38acf46 362 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 151 165 1.1E-57 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19120 97afa90b49ae48963bb1d2d8b38acf46 362 PANTHER PTHR30222 16 361 1.6E-173 T 13-09-2016 THL1_RS19120 97afa90b49ae48963bb1d2d8b38acf46 362 PIRSF PIRSF019574 4 362 4.2E-124 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS01925 fdd17826ffd7291afb86765608703421 264 SUPERFAMILY SSF52317 16 134 1.52E-21 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS01925 fdd17826ffd7291afb86765608703421 264 Gene3D G3DSA:1.10.10.60 151 205 6.7E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01925 fdd17826ffd7291afb86765608703421 264 Gene3D G3DSA:3.40.50.880 16 145 1.8E-16 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS01925 fdd17826ffd7291afb86765608703421 264 SUPERFAMILY SSF46689 205 252 9.86E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01925 fdd17826ffd7291afb86765608703421 264 PANTHER PTHR11019:SF90 19 38 4.5E-38 T 13-09-2016 THL1_RS01925 fdd17826ffd7291afb86765608703421 264 SMART SM00342 169 252 3.8E-27 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS01925 fdd17826ffd7291afb86765608703421 264 SUPERFAMILY SSF46689 153 203 1.43E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01925 fdd17826ffd7291afb86765608703421 264 PANTHER PTHR11019 64 260 4.5E-38 T 13-09-2016 THL1_RS01925 fdd17826ffd7291afb86765608703421 264 Gene3D G3DSA:1.10.10.60 206 252 2.0E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01925 fdd17826ffd7291afb86765608703421 264 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 206 248 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS01925 fdd17826ffd7291afb86765608703421 264 PANTHER PTHR11019:SF90 64 260 4.5E-38 T 13-09-2016 THL1_RS01925 fdd17826ffd7291afb86765608703421 264 PANTHER PTHR11019 19 38 4.5E-38 T 13-09-2016 THL1_RS01925 fdd17826ffd7291afb86765608703421 264 Pfam PF12833 Helix-turn-helix domain 175 250 1.2E-22 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS23415 dac77dea3b5b73ed2ca63af8c32e6cd7 227 SMART SM00448 1 113 2.6E-45 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS23415 dac77dea3b5b73ed2ca63af8c32e6cd7 227 Pfam PF00072 Response regulator receiver domain 3 113 9.8E-31 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS23415 dac77dea3b5b73ed2ca63af8c32e6cd7 227 Gene3D G3DSA:1.10.10.10 126 222 7.1E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS23415 dac77dea3b5b73ed2ca63af8c32e6cd7 227 SUPERFAMILY SSF52172 1 173 1.21E-43 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS23415 dac77dea3b5b73ed2ca63af8c32e6cd7 227 PANTHER PTHR26402:SF552 1 222 1.4E-115 T 13-09-2016 THL1_RS23415 dac77dea3b5b73ed2ca63af8c32e6cd7 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 6.8E-17 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS23415 dac77dea3b5b73ed2ca63af8c32e6cd7 227 PANTHER PTHR26402 1 222 1.4E-115 T 13-09-2016 THL1_RS23415 dac77dea3b5b73ed2ca63af8c32e6cd7 227 Gene3D G3DSA:3.40.50.2300 1 125 1.4E-41 T 13-09-2016 THL1_RS23415 dac77dea3b5b73ed2ca63af8c32e6cd7 227 SMART SM00862 146 220 1.8E-18 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS01305 c0353b9df32694a312df8b3ceff9a48c 230 SUPERFAMILY SSF51419 1 221 7.33E-81 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS01305 c0353b9df32694a312df8b3ceff9a48c 230 Gene3D G3DSA:3.20.20.10 1 227 4.8E-94 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS01305 c0353b9df32694a312df8b3ceff9a48c 230 Pfam PF01168 Alanine racemase, N-terminal domain 9 223 4.7E-35 T 13-09-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS01305 c0353b9df32694a312df8b3ceff9a48c 230 PIRSF PIRSF004848 1 229 2.6E-72 T 13-09-2016 IPR011078 Uncharacterised protein family UPF0001 THL1_RS01305 c0353b9df32694a312df8b3ceff9a48c 230 PANTHER PTHR10146 1 229 3.0E-104 T 13-09-2016 IPR011078 Uncharacterised protein family UPF0001 THL1_RS01305 c0353b9df32694a312df8b3ceff9a48c 230 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 76 90 - T 13-09-2016 IPR011078 Uncharacterised protein family UPF0001 THL1_RS01305 c0353b9df32694a312df8b3ceff9a48c 230 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 1 223 8.8E-76 T 13-09-2016 IPR011078 Uncharacterised protein family UPF0001 THL1_RS06450 a60ccc268af5f0b0251c46e9c1758a4c 497 Pfam PF05872 Bacterial protein of unknown function (DUF853) 10 496 3.9E-216 T 13-09-2016 IPR033186 Helicase HerA-like C-terminal THL1_RS06450 a60ccc268af5f0b0251c46e9c1758a4c 497 PANTHER PTHR30121 2 445 7.9E-158 T 13-09-2016 THL1_RS06450 a60ccc268af5f0b0251c46e9c1758a4c 497 SMART SM00382 25 331 5.2E-4 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS06450 a60ccc268af5f0b0251c46e9c1758a4c 497 Gene3D G3DSA:1.10.238.10 206 215 9.0E-4 T 13-09-2016 IPR011992 EF-hand domain pair THL1_RS06450 a60ccc268af5f0b0251c46e9c1758a4c 497 Gene3D G3DSA:1.10.238.10 128 169 9.0E-4 T 13-09-2016 IPR011992 EF-hand domain pair THL1_RS06450 a60ccc268af5f0b0251c46e9c1758a4c 497 PANTHER PTHR30121:SF3 2 445 7.9E-158 T 13-09-2016 THL1_RS06450 a60ccc268af5f0b0251c46e9c1758a4c 497 SUPERFAMILY SSF52540 5 383 4.74E-47 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06450 a60ccc268af5f0b0251c46e9c1758a4c 497 Gene3D G3DSA:3.40.50.300 216 383 3.5E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06450 a60ccc268af5f0b0251c46e9c1758a4c 497 Gene3D G3DSA:3.40.50.300 4 111 3.5E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24770 53dd57e30b95da8946edeb8bd70a6c89 606 PRINTS PR01032 Gene IV protein signature 533 555 3.9E-8 T 13-09-2016 THL1_RS24770 53dd57e30b95da8946edeb8bd70a6c89 606 PRINTS PR01032 Gene IV protein signature 480 508 3.9E-8 T 13-09-2016 THL1_RS24770 53dd57e30b95da8946edeb8bd70a6c89 606 PRINTS PR01032 Gene IV protein signature 407 430 3.9E-8 T 13-09-2016 THL1_RS24770 53dd57e30b95da8946edeb8bd70a6c89 606 SMART SM00965 202 253 6.4E-7 T 13-09-2016 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 THL1_RS24770 53dd57e30b95da8946edeb8bd70a6c89 606 Pfam PF00263 Bacterial type II and III secretion system protein 388 553 3.0E-42 T 13-09-2016 IPR004846 Type II/III secretion system GO:0009306 THL1_RS24770 53dd57e30b95da8946edeb8bd70a6c89 606 Gene3D G3DSA:1.25.40.10 25 148 1.0E-5 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS24770 53dd57e30b95da8946edeb8bd70a6c89 606 SUPERFAMILY SSF48452 22 99 2.81E-5 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS24770 53dd57e30b95da8946edeb8bd70a6c89 606 PANTHER PTHR30332 9 553 7.8E-72 T 13-09-2016 THL1_RS24770 53dd57e30b95da8946edeb8bd70a6c89 606 Pfam PF03958 Bacterial type II/III secretion system short domain 266 323 6.0E-7 T 13-09-2016 IPR005644 NolW-like THL1_RS24770 53dd57e30b95da8946edeb8bd70a6c89 606 Pfam PF07660 Secretin and TonB N terminus short domain 202 252 1.1E-8 T 13-09-2016 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 THL1_RS24770 53dd57e30b95da8946edeb8bd70a6c89 606 PRINTS PR00811 Bacterial general secretion pathway protein D signature 517 535 4.2E-10 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS24770 53dd57e30b95da8946edeb8bd70a6c89 606 PRINTS PR00811 Bacterial general secretion pathway protein D signature 417 427 4.2E-10 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS24770 53dd57e30b95da8946edeb8bd70a6c89 606 PRINTS PR00811 Bacterial general secretion pathway protein D signature 540 554 4.2E-10 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS24770 53dd57e30b95da8946edeb8bd70a6c89 606 PRINTS PR00811 Bacterial general secretion pathway protein D signature 326 336 4.2E-10 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS24770 53dd57e30b95da8946edeb8bd70a6c89 606 PANTHER PTHR30332:SF7 9 553 7.8E-72 T 13-09-2016 THL1_RS22655 626abf3ac592ead095acadae68e8ea5b 398 PANTHER PTHR11751 12 394 5.2E-141 T 13-09-2016 THL1_RS22655 626abf3ac592ead095acadae68e8ea5b 398 Pfam PF00155 Aminotransferase class I and II 30 376 9.4E-48 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS22655 626abf3ac592ead095acadae68e8ea5b 398 SUPERFAMILY SSF53383 2 396 1.93E-89 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS22655 626abf3ac592ead095acadae68e8ea5b 398 TIGRFAM TIGR03538 DapC_gpp: succinyldiaminopimelate transaminase 1 395 1.8E-206 T 13-09-2016 IPR019878 Succinyldiaminopimelate transaminase, DapC, beta/gammaproteobacteria GO:0009016|GO:0009089 THL1_RS22655 626abf3ac592ead095acadae68e8ea5b 398 PANTHER PTHR11751:SF354 12 394 5.2E-141 T 13-09-2016 THL1_RS22655 626abf3ac592ead095acadae68e8ea5b 398 Gene3D G3DSA:3.40.640.10 44 265 5.1E-62 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS22655 626abf3ac592ead095acadae68e8ea5b 398 Gene3D G3DSA:3.90.1150.10 266 396 4.7E-24 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS21440 180fa6efa8caa16393d16099af9c8570 294 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 291 1.4E-33 T 13-09-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 THL1_RS21440 180fa6efa8caa16393d16099af9c8570 294 PANTHER PTHR22981 1 292 4.0E-119 T 13-09-2016 THL1_RS21440 180fa6efa8caa16393d16099af9c8570 294 SUPERFAMILY SSF51735 3 163 3.94E-46 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS21440 180fa6efa8caa16393d16099af9c8570 294 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 162 4.4E-53 T 13-09-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 THL1_RS21440 180fa6efa8caa16393d16099af9c8570 294 SUPERFAMILY SSF48179 164 292 3.85E-39 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS21440 180fa6efa8caa16393d16099af9c8570 294 Gene3D G3DSA:3.40.50.720 2 163 5.3E-60 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS21440 180fa6efa8caa16393d16099af9c8570 294 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 13-09-2016 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 THL1_RS21440 180fa6efa8caa16393d16099af9c8570 294 PIRSF PIRSF000103 1 294 4.0E-81 T 13-09-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 THL1_RS21440 180fa6efa8caa16393d16099af9c8570 294 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 6 292 8.3E-121 T 13-09-2016 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|UniPathway: UPA00362 THL1_RS21440 180fa6efa8caa16393d16099af9c8570 294 Gene3D G3DSA:1.10.1040.10 165 293 6.6E-43 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS26180 c7bd4de3cdf682882f507451fd804f75 307 Gene3D G3DSA:3.30.470.10 8 130 1.0E-40 T 13-09-2016 THL1_RS26180 c7bd4de3cdf682882f507451fd804f75 307 PANTHER PTHR11825 1 305 2.0E-123 T 13-09-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 THL1_RS26180 c7bd4de3cdf682882f507451fd804f75 307 SUPERFAMILY SSF56752 1 303 7.33E-106 T 13-09-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 THL1_RS26180 c7bd4de3cdf682882f507451fd804f75 307 ProSitePatterns PS00770 Aminotransferases class-IV signature. 194 222 - T 13-09-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: REACT_13 THL1_RS26180 c7bd4de3cdf682882f507451fd804f75 307 PANTHER PTHR11825:SF7 1 305 2.0E-123 T 13-09-2016 THL1_RS26180 c7bd4de3cdf682882f507451fd804f75 307 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 11 306 4.9E-142 T 13-09-2016 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|UniPathway: UPA00047|UniPathway: UPA00048|UniPathway: UPA00049 THL1_RS26180 c7bd4de3cdf682882f507451fd804f75 307 Pfam PF01063 Amino-transferase class IV 36 267 9.5E-56 T 13-09-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 THL1_RS26180 c7bd4de3cdf682882f507451fd804f75 307 Gene3D G3DSA:3.20.10.10 134 295 1.1E-59 T 13-09-2016 THL1_RS07430 8c9769de2e4ebf1f2972b521fdbad63f 148 SUPERFAMILY SSF47413 29 88 1.66E-8 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS07430 8c9769de2e4ebf1f2972b521fdbad63f 148 SMART SM00530 34 90 0.003 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS07430 8c9769de2e4ebf1f2972b521fdbad63f 148 Pfam PF01381 Helix-turn-helix 44 87 6.8E-6 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS07430 8c9769de2e4ebf1f2972b521fdbad63f 148 Gene3D G3DSA:1.10.260.40 29 86 1.5E-9 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 PANTHER PTHR19370 4 264 1.5E-80 T 13-09-2016 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 PRINTS PR00406 Cytochrome B5 reductase signature 212 220 3.5E-8 T 13-09-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 PRINTS PR00406 Cytochrome B5 reductase signature 153 164 3.5E-8 T 13-09-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 PRINTS PR00406 Cytochrome B5 reductase signature 116 135 3.5E-8 T 13-09-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 PRINTS PR00406 Cytochrome B5 reductase signature 91 105 3.5E-8 T 13-09-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 Gene3D G3DSA:2.40.30.10 2 94 7.7E-25 T 13-09-2016 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 SUPERFAMILY SSF52343 94 242 1.96E-35 T 13-09-2016 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 273 346 1.5E-16 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 Gene3D G3DSA:3.10.20.30 239 356 1.6E-33 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 PANTHER PTHR19370:SF93 4 264 1.5E-80 T 13-09-2016 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 SUPERFAMILY SSF54292 235 355 1.7E-28 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 Pfam PF00970 Oxidoreductase FAD-binding domain 8 103 3.0E-13 T 13-09-2016 IPR008333 Oxidoreductase, FAD-binding domain THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 55 62 6.8E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 153 164 6.8E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 116 135 6.8E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 141 150 6.8E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 304 312 - T 13-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 Gene3D G3DSA:3.40.50.80 95 238 3.1E-41 T 13-09-2016 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 SUPERFAMILY SSF63380 2 105 1.7E-25 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 Pfam PF00175 Oxidoreductase NAD-binding domain 118 226 5.8E-18 T 13-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THL1_RS15760 99d682300d115279bbebd5a5e96e9d01 358 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 4 356 2.1E-146 T 13-09-2016 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.-|UniPathway: UPA00930 THL1_RS00745 898407a8d744746ad481354bee6a6ace 323 SUPERFAMILY SSF55785 38 153 2.9E-21 T 13-09-2016 IPR000014 PAS domain THL1_RS00745 898407a8d744746ad481354bee6a6ace 323 SMART SM00091 33 102 0.0054 T 13-09-2016 IPR000014 PAS domain THL1_RS00745 898407a8d744746ad481354bee6a6ace 323 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 158 322 2.0E-42 T 13-09-2016 IPR000160 GGDEF domain THL1_RS00745 898407a8d744746ad481354bee6a6ace 323 Gene3D G3DSA:3.30.450.20 26 149 1.1E-25 T 13-09-2016 THL1_RS00745 898407a8d744746ad481354bee6a6ace 323 SMART SM00267 151 322 1.2E-52 T 13-09-2016 IPR000160 GGDEF domain THL1_RS00745 898407a8d744746ad481354bee6a6ace 323 Pfam PF00990 Diguanylate cyclase, GGDEF domain 162 318 6.3E-41 T 13-09-2016 IPR000160 GGDEF domain THL1_RS00745 898407a8d744746ad481354bee6a6ace 323 SMART SM00086 108 151 8.4E-5 T 13-09-2016 IPR001610 PAC motif THL1_RS00745 898407a8d744746ad481354bee6a6ace 323 Gene3D G3DSA:3.30.70.270 164 322 9.9E-52 T 13-09-2016 THL1_RS00745 898407a8d744746ad481354bee6a6ace 323 Pfam PF08447 PAS fold 56 145 1.7E-23 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS00745 898407a8d744746ad481354bee6a6ace 323 PANTHER PTHR10799 194 321 7.8E-31 T 13-09-2016 THL1_RS00745 898407a8d744746ad481354bee6a6ace 323 SUPERFAMILY SSF55073 167 321 4.16E-47 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS00745 898407a8d744746ad481354bee6a6ace 323 PANTHER PTHR10799:SF750 194 321 7.8E-31 T 13-09-2016 THL1_RS00745 898407a8d744746ad481354bee6a6ace 323 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 29 158 8.6E-15 T 13-09-2016 IPR000014 PAS domain THL1_RS10750 d84b8de608910b476b64bf7a8517424b 416 PANTHER PTHR30489 1 416 5.0E-124 T 13-09-2016 THL1_RS10750 d84b8de608910b476b64bf7a8517424b 416 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 4 416 1.9E-162 T 13-09-2016 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 THL1_RS10750 d84b8de608910b476b64bf7a8517424b 416 Pfam PF02687 FtsX-like permease family 276 409 5.3E-20 T 13-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 THL1_RS10750 d84b8de608910b476b64bf7a8517424b 416 PANTHER PTHR30489:SF8 1 416 5.0E-124 T 13-09-2016 THL1_RS10750 d84b8de608910b476b64bf7a8517424b 416 Pfam PF12704 MacB-like periplasmic core domain 27 238 1.1E-16 T 13-09-2016 IPR025857 MacB-like periplasmic core domain THL1_RS27000 5953d06292decb7222a1b62f6ff19355 475 PANTHER PTHR11785:SF77 3 469 6.4E-240 T 13-09-2016 THL1_RS27000 5953d06292decb7222a1b62f6ff19355 475 PIRSF PIRSF006060 1 471 1.4E-47 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS27000 5953d06292decb7222a1b62f6ff19355 475 TIGRFAM TIGR00905 2A0302: transporter, basic amino acid/polyamine antiporter (APA) family 1 475 6.9E-198 T 13-09-2016 IPR004754 Amino acid antiporter GO:0006865|GO:0016021 THL1_RS27000 5953d06292decb7222a1b62f6ff19355 475 TIGRFAM TIGR03810 arg_ornith_anti: arginine-ornithine antiporter 7 474 1.1E-222 T 13-09-2016 IPR022461 Arginine/ornithine antiporter GO:0005887|GO:0006527|GO:0043858 THL1_RS27000 5953d06292decb7222a1b62f6ff19355 475 Pfam PF13520 Amino acid permease 12 415 1.7E-73 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS27000 5953d06292decb7222a1b62f6ff19355 475 PANTHER PTHR11785 3 469 6.4E-240 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS20040 ee5a2c546ce41c8bb064cef297c637ea 268 Pfam PF00106 short chain dehydrogenase 8 191 1.6E-47 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20040 ee5a2c546ce41c8bb064cef297c637ea 268 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 182 1.7E-4 T 13-09-2016 THL1_RS20040 ee5a2c546ce41c8bb064cef297c637ea 268 Gene3D G3DSA:3.40.50.720 7 248 1.1E-59 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20040 ee5a2c546ce41c8bb064cef297c637ea 268 SUPERFAMILY SSF51735 1 259 2.33E-61 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20040 ee5a2c546ce41c8bb064cef297c637ea 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS20040 ee5a2c546ce41c8bb064cef297c637ea 268 PANTHER PTHR24320 1 220 1.1E-40 T 13-09-2016 THL1_RS20040 ee5a2c546ce41c8bb064cef297c637ea 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 2.8E-21 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20040 ee5a2c546ce41c8bb064cef297c637ea 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 2.8E-21 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20040 ee5a2c546ce41c8bb064cef297c637ea 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 2.8E-21 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20040 ee5a2c546ce41c8bb064cef297c637ea 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.8E-21 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20040 ee5a2c546ce41c8bb064cef297c637ea 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 2.8E-21 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20040 ee5a2c546ce41c8bb064cef297c637ea 268 PANTHER PTHR24320:SF1 1 220 1.1E-40 T 13-09-2016 THL1_RS20040 ee5a2c546ce41c8bb064cef297c637ea 268 PIRSF PIRSF000126 2 262 2.4E-51 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20040 ee5a2c546ce41c8bb064cef297c637ea 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 2.8E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20040 ee5a2c546ce41c8bb064cef297c637ea 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.8E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20040 ee5a2c546ce41c8bb064cef297c637ea 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.8E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 SUPERFAMILY SSF47831 204 316 5.49E-30 T 13-09-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 Gene3D G3DSA:3.30.450.40 1 162 7.4E-50 T 13-09-2016 IPR029016 GAF domain-like THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 620 638 - T 13-09-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 179 736 1.8E-140 T 13-09-2016 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 SUPERFAMILY SSF51621 428 714 1.73E-102 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 Pfam PF05524 PEP-utilising enzyme, N-terminal 180 301 1.1E-27 T 13-09-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 SUPERFAMILY SSF52009 300 419 1.44E-28 T 13-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 Pfam PF00391 PEP-utilising enzyme, mobile domain 327 399 5.1E-17 T 13-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 Gene3D G3DSA:1.10.274.10 204 307 5.4E-35 T 13-09-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 SUPERFAMILY SSF55781 2 158 2.18E-32 T 13-09-2016 IPR029016 GAF domain-like THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 Pfam PF01590 GAF domain 17 152 1.2E-15 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 SMART SM00065 17 164 4.2E-24 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 PANTHER PTHR22931 200 723 8.8E-282 T 13-09-2016 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 PANTHER PTHR22931:SF23 200 723 8.8E-282 T 13-09-2016 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 467 486 7.1E-24 T 13-09-2016 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 620 635 7.1E-24 T 13-09-2016 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 673 685 7.1E-24 T 13-09-2016 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 637 652 7.1E-24 T 13-09-2016 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 427 714 1.6E-98 T 13-09-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 Gene3D G3DSA:3.20.20.60 431 739 2.7E-103 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS01480 6f20eb2e8433e4552d86ea16c5eee59e 759 Gene3D G3DSA:3.50.30.10 308 430 3.3E-32 T 13-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THL1_RS11100 937f8ce036b88b29c214fb4f1d9ab315 309 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 146 306 2.2E-26 T 13-09-2016 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 THL1_RS11100 937f8ce036b88b29c214fb4f1d9ab315 309 PRINTS PR00086 L-lactate dehydrogenase signature 28 52 7.7E-30 T 13-09-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THL1_RS11100 937f8ce036b88b29c214fb4f1d9ab315 309 PRINTS PR00086 L-lactate dehydrogenase signature 116 136 7.7E-30 T 13-09-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THL1_RS11100 937f8ce036b88b29c214fb4f1d9ab315 309 PRINTS PR00086 L-lactate dehydrogenase signature 140 158 7.7E-30 T 13-09-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THL1_RS11100 937f8ce036b88b29c214fb4f1d9ab315 309 PRINTS PR00086 L-lactate dehydrogenase signature 170 183 7.7E-30 T 13-09-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THL1_RS11100 937f8ce036b88b29c214fb4f1d9ab315 309 PRINTS PR00086 L-lactate dehydrogenase signature 3 27 7.7E-30 T 13-09-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THL1_RS11100 937f8ce036b88b29c214fb4f1d9ab315 309 Gene3D G3DSA:3.90.110.10 144 306 3.8E-48 T 13-09-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 THL1_RS11100 937f8ce036b88b29c214fb4f1d9ab315 309 SUPERFAMILY SSF56327 144 302 7.78E-46 T 13-09-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 THL1_RS11100 937f8ce036b88b29c214fb4f1d9ab315 309 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 3 142 1.7E-37 T 13-09-2016 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 THL1_RS11100 937f8ce036b88b29c214fb4f1d9ab315 309 Hamap MF_00487 Malate dehydrogenase [mdh]. 2 307 35.34 T 13-09-2016 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 THL1_RS11100 937f8ce036b88b29c214fb4f1d9ab315 309 PANTHER PTHR11540 3 305 1.3E-102 T 13-09-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THL1_RS11100 937f8ce036b88b29c214fb4f1d9ab315 309 PIRSF PIRSF000102 1 309 6.8E-91 T 13-09-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THL1_RS11100 937f8ce036b88b29c214fb4f1d9ab315 309 Gene3D G3DSA:3.40.50.720 2 142 1.4E-42 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11100 937f8ce036b88b29c214fb4f1d9ab315 309 SUPERFAMILY SSF51735 2 142 2.36E-42 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11100 937f8ce036b88b29c214fb4f1d9ab315 309 PANTHER PTHR11540:SF16 3 305 1.3E-102 T 13-09-2016 THL1_RS00820 ae09ce50cd7fbec33775d838e1818de7 248 SMART SM00382 26 219 2.7E-20 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS00820 ae09ce50cd7fbec33775d838e1818de7 248 Pfam PF00005 ABC transporter 17 171 3.2E-34 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS00820 ae09ce50cd7fbec33775d838e1818de7 248 PIRSF PIRSF039085 1 247 5.0E-111 T 13-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 THL1_RS00820 ae09ce50cd7fbec33775d838e1818de7 248 PANTHER PTHR24220 3 246 5.2E-137 T 13-09-2016 THL1_RS00820 ae09ce50cd7fbec33775d838e1818de7 248 PANTHER PTHR24220:SF327 3 246 5.2E-137 T 13-09-2016 THL1_RS00820 ae09ce50cd7fbec33775d838e1818de7 248 SUPERFAMILY SSF52540 1 241 1.15E-75 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00820 ae09ce50cd7fbec33775d838e1818de7 248 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS00820 ae09ce50cd7fbec33775d838e1818de7 248 Gene3D G3DSA:3.40.50.300 1 243 2.1E-82 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28175 dc2c58f875af8721297465c87dbd5a42 482 PRINTS PR00175 Sodium/alanine symporter signature 203 222 4.2E-47 T 13-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THL1_RS28175 dc2c58f875af8721297465c87dbd5a42 482 PRINTS PR00175 Sodium/alanine symporter signature 175 193 4.2E-47 T 13-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THL1_RS28175 dc2c58f875af8721297465c87dbd5a42 482 PRINTS PR00175 Sodium/alanine symporter signature 294 312 4.2E-47 T 13-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THL1_RS28175 dc2c58f875af8721297465c87dbd5a42 482 PRINTS PR00175 Sodium/alanine symporter signature 84 106 4.2E-47 T 13-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THL1_RS28175 dc2c58f875af8721297465c87dbd5a42 482 PRINTS PR00175 Sodium/alanine symporter signature 401 421 4.2E-47 T 13-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THL1_RS28175 dc2c58f875af8721297465c87dbd5a42 482 PRINTS PR00175 Sodium/alanine symporter signature 340 362 4.2E-47 T 13-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THL1_RS28175 dc2c58f875af8721297465c87dbd5a42 482 Pfam PF01235 Sodium:alanine symporter family 50 445 1.5E-145 T 13-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THL1_RS28175 dc2c58f875af8721297465c87dbd5a42 482 PANTHER PTHR30330:SF1 1 466 7.9E-247 T 13-09-2016 THL1_RS28175 dc2c58f875af8721297465c87dbd5a42 482 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 84 99 - T 13-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THL1_RS28175 dc2c58f875af8721297465c87dbd5a42 482 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 432 9.2E-140 T 13-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THL1_RS28175 dc2c58f875af8721297465c87dbd5a42 482 PANTHER PTHR30330 1 466 7.9E-247 T 13-09-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THL1_RS22100 738004fad1f63a1b398ad599259ac0ab 333 Pfam PF13103 TonB C terminal 246 308 3.1E-11 T 13-09-2016 IPR006260 TonB, C-terminal GO:0006810 THL1_RS22100 738004fad1f63a1b398ad599259ac0ab 333 Gene3D G3DSA:3.30.1150.10 213 331 1.5E-34 T 13-09-2016 THL1_RS22100 738004fad1f63a1b398ad599259ac0ab 333 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 252 328 4.6E-14 T 13-09-2016 IPR006260 TonB, C-terminal GO:0006810 THL1_RS22100 738004fad1f63a1b398ad599259ac0ab 333 TIGRFAM TIGR02794 tolA_full: protein TolA 15 328 1.0E-49 T 13-09-2016 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0006810|GO:0016020 THL1_RS22100 738004fad1f63a1b398ad599259ac0ab 333 SUPERFAMILY SSF74653 215 330 2.94E-24 T 13-09-2016 THL1_RS08210 89bc680c4085d62523fa2cb392a85522 931 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 75 100 1.4E-39 T 13-09-2016 THL1_RS08210 89bc680c4085d62523fa2cb392a85522 931 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 415 434 1.4E-39 T 13-09-2016 THL1_RS08210 89bc680c4085d62523fa2cb392a85522 931 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 150 171 1.4E-39 T 13-09-2016 THL1_RS08210 89bc680c4085d62523fa2cb392a85522 931 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 1.4E-39 T 13-09-2016 THL1_RS08210 89bc680c4085d62523fa2cb392a85522 931 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 1.4E-39 T 13-09-2016 THL1_RS08210 89bc680c4085d62523fa2cb392a85522 931 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 103 123 1.4E-39 T 13-09-2016 THL1_RS08210 89bc680c4085d62523fa2cb392a85522 931 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 306 318 1.4E-39 T 13-09-2016 THL1_RS08210 89bc680c4085d62523fa2cb392a85522 931 PANTHER PTHR22773 1 549 2.2E-238 T 13-09-2016 THL1_RS08210 89bc680c4085d62523fa2cb392a85522 931 PANTHER PTHR22773:SF46 1 549 2.2E-238 T 13-09-2016 THL1_RS08210 89bc680c4085d62523fa2cb392a85522 931 Pfam PF13244 Domain of unknown function (DUF4040) 611 674 2.2E-19 T 13-09-2016 IPR025383 Domain of unknown function DUF4040 THL1_RS08210 89bc680c4085d62523fa2cb392a85522 931 Pfam PF00361 Proton-conducting membrane transporter 126 402 8.6E-66 T 13-09-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 THL1_RS08210 89bc680c4085d62523fa2cb392a85522 931 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 788 911 3.9E-37 T 13-09-2016 IPR007182 Na+/H+ antiporter MnhB subunit-related protein THL1_RS08210 89bc680c4085d62523fa2cb392a85522 931 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 61 113 1.8E-12 T 13-09-2016 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal THL1_RS21000 876fc17d7994fa4b364e561834c15384 96 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 13 87 2.5E-11 T 13-09-2016 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 THL1_RS21290 eb2deee297f164bc2e1e865859631fe4 300 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 169 3.1E-29 T 13-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 THL1_RS21290 eb2deee297f164bc2e1e865859631fe4 300 Gene3D G3DSA:3.30.300.20 195 294 1.7E-40 T 13-09-2016 IPR015946 K homology domain-like, alpha/beta THL1_RS21290 eb2deee297f164bc2e1e865859631fe4 300 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 12 32 3.9E-6 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS21290 eb2deee297f164bc2e1e865859631fe4 300 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 61 76 3.9E-6 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS21290 eb2deee297f164bc2e1e865859631fe4 300 PANTHER PTHR11649:SF3 7 299 9.9E-118 T 13-09-2016 THL1_RS21290 eb2deee297f164bc2e1e865859631fe4 300 TIGRFAM TIGR00436 era: GTP-binding protein Era 10 280 1.3E-98 T 13-09-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 THL1_RS21290 eb2deee297f164bc2e1e865859631fe4 300 SUPERFAMILY SSF54814 183 298 4.25E-43 T 13-09-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 THL1_RS21290 eb2deee297f164bc2e1e865859631fe4 300 SUPERFAMILY SSF52540 12 205 1.34E-44 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21290 eb2deee297f164bc2e1e865859631fe4 300 Gene3D G3DSA:3.40.50.300 11 194 3.1E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21290 eb2deee297f164bc2e1e865859631fe4 300 Pfam PF01926 50S ribosome-binding GTPase 12 126 2.0E-23 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS21290 eb2deee297f164bc2e1e865859631fe4 300 Pfam PF07650 KH domain 210 285 5.1E-21 T 13-09-2016 IPR004044 K Homology domain, type 2 GO:0003723 THL1_RS21290 eb2deee297f164bc2e1e865859631fe4 300 Hamap MF_00367 GTPase Era [era]. 7 297 36.31 T 13-09-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 THL1_RS21290 eb2deee297f164bc2e1e865859631fe4 300 PANTHER PTHR11649 7 299 9.9E-118 T 13-09-2016 THL1_RS06130 6961e16658bab72d0f25731d11996ef5 682 Gene3D G3DSA:3.40.50.2300 1 126 4.8E-38 T 13-09-2016 THL1_RS06130 6961e16658bab72d0f25731d11996ef5 682 SMART SM00052 425 670 5.4E-106 T 13-09-2016 IPR001633 EAL domain THL1_RS06130 6961e16658bab72d0f25731d11996ef5 682 SUPERFAMILY SSF52172 1 130 2.28E-38 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS06130 6961e16658bab72d0f25731d11996ef5 682 PANTHER PTHR33121:SF13 365 679 1.9E-88 T 13-09-2016 THL1_RS06130 6961e16658bab72d0f25731d11996ef5 682 Pfam PF00563 EAL domain 431 665 2.3E-73 T 13-09-2016 IPR001633 EAL domain THL1_RS06130 6961e16658bab72d0f25731d11996ef5 682 PANTHER PTHR33121 365 679 1.9E-88 T 13-09-2016 THL1_RS06130 6961e16658bab72d0f25731d11996ef5 682 Pfam PF00072 Response regulator receiver domain 1 112 3.3E-28 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS06130 6961e16658bab72d0f25731d11996ef5 682 Gene3D G3DSA:3.20.20.450 429 675 1.7E-94 T 13-09-2016 IPR001633 EAL domain THL1_RS06130 6961e16658bab72d0f25731d11996ef5 682 Gene3D G3DSA:3.30.70.270 249 421 3.6E-15 T 13-09-2016 THL1_RS06130 6961e16658bab72d0f25731d11996ef5 682 SMART SM00267 236 415 1.7E-5 T 13-09-2016 IPR000160 GGDEF domain THL1_RS06130 6961e16658bab72d0f25731d11996ef5 682 SMART SM00448 1 112 8.3E-35 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS06130 6961e16658bab72d0f25731d11996ef5 682 SUPERFAMILY SSF141868 430 677 4.58E-86 T 13-09-2016 IPR001633 EAL domain THL1_RS06130 6961e16658bab72d0f25731d11996ef5 682 Pfam PF00990 Diguanylate cyclase, GGDEF domain 248 408 3.8E-10 T 13-09-2016 IPR000160 GGDEF domain THL1_RS06130 6961e16658bab72d0f25731d11996ef5 682 SUPERFAMILY SSF55073 253 409 4.08E-12 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS00065 031e7d5b9c9bc1d214d3d86543ce63bb 315 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 10 299 7.4E-165 T 13-09-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THL1_RS00065 031e7d5b9c9bc1d214d3d86543ce63bb 315 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 115 139 1.8E-69 T 13-09-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THL1_RS00065 031e7d5b9c9bc1d214d3d86543ce63bb 315 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 84 104 1.8E-69 T 13-09-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THL1_RS00065 031e7d5b9c9bc1d214d3d86543ce63bb 315 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 164 179 1.8E-69 T 13-09-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THL1_RS00065 031e7d5b9c9bc1d214d3d86543ce63bb 315 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 63 78 1.8E-69 T 13-09-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THL1_RS00065 031e7d5b9c9bc1d214d3d86543ce63bb 315 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 141 161 1.8E-69 T 13-09-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THL1_RS00065 031e7d5b9c9bc1d214d3d86543ce63bb 315 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 253 269 1.8E-69 T 13-09-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THL1_RS00065 031e7d5b9c9bc1d214d3d86543ce63bb 315 Gene3D G3DSA:3.30.930.10 4 216 3.5E-108 T 13-09-2016 THL1_RS00065 031e7d5b9c9bc1d214d3d86543ce63bb 315 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 11 291 9.5E-154 T 13-09-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THL1_RS00065 031e7d5b9c9bc1d214d3d86543ce63bb 315 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 9 293 61.863 T 13-09-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THL1_RS00065 031e7d5b9c9bc1d214d3d86543ce63bb 315 SUPERFAMILY SSF55681 10 291 1.49E-137 T 13-09-2016 THL1_RS00065 031e7d5b9c9bc1d214d3d86543ce63bb 315 PANTHER PTHR30075 1 315 7.0E-267 T 13-09-2016 THL1_RS00065 031e7d5b9c9bc1d214d3d86543ce63bb 315 Gene3D G3DSA:1.20.58.180 217 298 1.8E-37 T 13-09-2016 THL1_RS03885 b5548674f9edbd3a79d34b7dd3eb6bfc 204 PANTHER PTHR21327 3 203 1.6E-130 T 13-09-2016 THL1_RS03885 b5548674f9edbd3a79d34b7dd3eb6bfc 204 Pfam PF00925 GTP cyclohydrolase II 6 170 1.5E-67 T 13-09-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 THL1_RS03885 b5548674f9edbd3a79d34b7dd3eb6bfc 204 SUPERFAMILY SSF142695 3 172 9.15E-66 T 13-09-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 THL1_RS03885 b5548674f9edbd3a79d34b7dd3eb6bfc 204 PANTHER PTHR21327:SF14 3 203 1.6E-130 T 13-09-2016 THL1_RS03885 b5548674f9edbd3a79d34b7dd3eb6bfc 204 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 1 196 45.661 T 13-09-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 THL1_RS03885 b5548674f9edbd3a79d34b7dd3eb6bfc 204 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 7 194 1.3E-78 T 13-09-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 THL1_RS05040 4bc5230a4b0adab91cfdd986b8d0395a 140 Gene3D G3DSA:3.40.630.30 1 128 7.0E-23 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS05040 4bc5230a4b0adab91cfdd986b8d0395a 140 Pfam PF00583 Acetyltransferase (GNAT) family 53 121 1.6E-7 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS05040 4bc5230a4b0adab91cfdd986b8d0395a 140 SUPERFAMILY SSF55729 1 129 2.99E-21 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS05040 4bc5230a4b0adab91cfdd986b8d0395a 140 PANTHER PTHR23091 1 133 8.9E-12 T 13-09-2016 THL1_RS11815 19128ed5426c0fece60648765385dde7 317 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 7 314 1.3E-71 T 13-09-2016 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|UniPathway: UPA00028 THL1_RS11815 19128ed5426c0fece60648765385dde7 317 SUPERFAMILY SSF48179 189 312 5.78E-27 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS11815 19128ed5426c0fece60648765385dde7 317 Pfam PF02558 Ketopantoate reductase PanE/ApbA 8 157 4.6E-34 T 13-09-2016 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|UniPathway: UPA00028 THL1_RS11815 19128ed5426c0fece60648765385dde7 317 SUPERFAMILY SSF51735 7 166 1.06E-12 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11815 19128ed5426c0fece60648765385dde7 317 PANTHER PTHR21708 2 316 1.6E-63 T 13-09-2016 THL1_RS11815 19128ed5426c0fece60648765385dde7 317 Gene3D G3DSA:3.40.50.720 4 183 1.3E-45 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11815 19128ed5426c0fece60648765385dde7 317 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 189 311 7.7E-25 T 13-09-2016 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|UniPathway: UPA00028 THL1_RS11815 19128ed5426c0fece60648765385dde7 317 Gene3D G3DSA:1.10.1040.10 190 311 8.1E-27 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS17300 0cd7cfa899072180b1c13f8b6ce5a662 90 Pfam PF05101 Type IV secretory pathway, VirB3-like protein 12 85 1.9E-10 T 13-09-2016 IPR007792 Type IV secretion system, VirB3 / TrbD / AvhB THL1_RS17300 0cd7cfa899072180b1c13f8b6ce5a662 90 ProDom PD012561 TRBD PLASMID CONJUGAL TRANSFER PRECURSOR SIGNAL MATING FORMATION PROBABLE PAIR 15 86 4.0E-5 T 13-09-2016 THL1_RS17300 0cd7cfa899072180b1c13f8b6ce5a662 90 PIRSF PIRSF017854 5 90 1.4E-34 T 13-09-2016 IPR016704 Conjugal transfer, TrbD THL1_RS15565 c60b90eb7f6d9fda994df9b7e0e6509f 109 PANTHER PTHR40606 2 109 3.2E-19 T 13-09-2016 THL1_RS15565 c60b90eb7f6d9fda994df9b7e0e6509f 109 SUPERFAMILY SSF160113 3 57 3.01E-11 T 13-09-2016 IPR010879 Domain of unknown function DUF1508 THL1_RS15565 c60b90eb7f6d9fda994df9b7e0e6509f 109 Gene3D G3DSA:3.30.160.160 3 49 3.2E-8 T 13-09-2016 IPR010879 Domain of unknown function DUF1508 THL1_RS15565 c60b90eb7f6d9fda994df9b7e0e6509f 109 Gene3D G3DSA:3.30.160.160 56 99 8.4E-10 T 13-09-2016 IPR010879 Domain of unknown function DUF1508 THL1_RS15565 c60b90eb7f6d9fda994df9b7e0e6509f 109 SUPERFAMILY SSF160113 55 108 2.62E-9 T 13-09-2016 IPR010879 Domain of unknown function DUF1508 THL1_RS15565 c60b90eb7f6d9fda994df9b7e0e6509f 109 Pfam PF07411 Domain of unknown function (DUF1508) 61 108 1.7E-13 T 13-09-2016 IPR010879 Domain of unknown function DUF1508 THL1_RS15565 c60b90eb7f6d9fda994df9b7e0e6509f 109 Pfam PF07411 Domain of unknown function (DUF1508) 11 54 9.6E-7 T 13-09-2016 IPR010879 Domain of unknown function DUF1508 THL1_RS15565 c60b90eb7f6d9fda994df9b7e0e6509f 109 PANTHER PTHR40606:SF1 2 109 3.2E-19 T 13-09-2016 THL1_RS19005 c0e30534f5516c448bf14006695a2888 426 TIGRFAM TIGR00896 CynX: cyanate transporter 43 393 9.7E-137 T 13-09-2016 IPR004747 Cyanate transport system protein GO:0016021 THL1_RS19005 c0e30534f5516c448bf14006695a2888 426 SUPERFAMILY SSF103473 26 415 5.1E-46 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS19005 c0e30534f5516c448bf14006695a2888 426 Gene3D G3DSA:1.20.1250.20 233 409 1.6E-16 T 13-09-2016 THL1_RS19005 c0e30534f5516c448bf14006695a2888 426 Gene3D G3DSA:1.20.1250.20 41 225 1.2E-11 T 13-09-2016 THL1_RS19005 c0e30534f5516c448bf14006695a2888 426 PANTHER PTHR23523:SF2 24 426 3.8E-171 T 13-09-2016 THL1_RS19005 c0e30534f5516c448bf14006695a2888 426 Pfam PF07690 Major Facilitator Superfamily 59 375 2.9E-16 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS19005 c0e30534f5516c448bf14006695a2888 426 PANTHER PTHR23523 24 426 3.8E-171 T 13-09-2016 THL1_RS20305 faf04a7a2aaefb7c021dcb5a95962e93 288 SUPERFAMILY SSF53850 87 285 3.15E-41 T 13-09-2016 THL1_RS20305 faf04a7a2aaefb7c021dcb5a95962e93 288 Gene3D G3DSA:3.40.190.10 172 256 2.3E-24 T 13-09-2016 THL1_RS20305 faf04a7a2aaefb7c021dcb5a95962e93 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.8E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS20305 faf04a7a2aaefb7c021dcb5a95962e93 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.8E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS20305 faf04a7a2aaefb7c021dcb5a95962e93 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.8E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS20305 faf04a7a2aaefb7c021dcb5a95962e93 288 PANTHER PTHR30126:SF11 1 283 2.4E-69 T 13-09-2016 THL1_RS20305 faf04a7a2aaefb7c021dcb5a95962e93 288 Gene3D G3DSA:3.40.190.10 89 171 2.8E-21 T 13-09-2016 THL1_RS20305 faf04a7a2aaefb7c021dcb5a95962e93 288 Gene3D G3DSA:1.10.10.10 5 78 8.4E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20305 faf04a7a2aaefb7c021dcb5a95962e93 288 PANTHER PTHR30126 1 283 2.4E-69 T 13-09-2016 THL1_RS20305 faf04a7a2aaefb7c021dcb5a95962e93 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 61 3.9E-18 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS20305 faf04a7a2aaefb7c021dcb5a95962e93 288 SUPERFAMILY SSF46785 6 106 1.66E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20305 faf04a7a2aaefb7c021dcb5a95962e93 288 Pfam PF03466 LysR substrate binding domain 87 283 4.5E-45 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS20305 faf04a7a2aaefb7c021dcb5a95962e93 288 TIGRFAM TIGR03339 phn_lysR: aminoethylphosphonate catabolism associated LysR family transcriptional regulator 5 281 5.8E-125 T 13-09-2016 IPR017724 Aminoethylphosphonate utilisation-associated transcription regulator, LysR-type THL1_RS04475 a8477917341f35fe61edb72b4a906df3 145 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 124 7.5E-7 T 13-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain THL1_RS04475 a8477917341f35fe61edb72b4a906df3 145 SUPERFAMILY SSF54593 8 129 4.4E-22 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS04475 a8477917341f35fe61edb72b4a906df3 145 PANTHER PTHR35006 5 141 1.0E-44 T 13-09-2016 THL1_RS04475 a8477917341f35fe61edb72b4a906df3 145 Gene3D G3DSA:3.10.180.10 6 125 1.1E-28 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS23900 9db0bc07e50d1904a4aaacd9d0d08b9f 327 Gene3D G3DSA:3.90.660.10 44 110 5.3E-56 T 13-09-2016 THL1_RS23900 9db0bc07e50d1904a4aaacd9d0d08b9f 327 Gene3D G3DSA:3.90.660.10 187 285 5.3E-56 T 13-09-2016 THL1_RS23900 9db0bc07e50d1904a4aaacd9d0d08b9f 327 Pfam PF01593 Flavin containing amine oxidoreductase 113 324 2.2E-10 T 13-09-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 THL1_RS23900 9db0bc07e50d1904a4aaacd9d0d08b9f 327 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 71 1.4E-15 T 13-09-2016 THL1_RS23900 9db0bc07e50d1904a4aaacd9d0d08b9f 327 Gene3D G3DSA:3.50.50.60 287 327 4.5E-53 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23900 9db0bc07e50d1904a4aaacd9d0d08b9f 327 Gene3D G3DSA:3.50.50.60 111 186 4.5E-53 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23900 9db0bc07e50d1904a4aaacd9d0d08b9f 327 Gene3D G3DSA:3.50.50.60 4 41 4.5E-53 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23900 9db0bc07e50d1904a4aaacd9d0d08b9f 327 SUPERFAMILY SSF51905 287 327 2.16E-36 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23900 9db0bc07e50d1904a4aaacd9d0d08b9f 327 SUPERFAMILY SSF51905 2 196 2.16E-36 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23900 9db0bc07e50d1904a4aaacd9d0d08b9f 327 PANTHER PTHR16128:SF5 5 327 5.0E-80 T 13-09-2016 THL1_RS23900 9db0bc07e50d1904a4aaacd9d0d08b9f 327 PANTHER PTHR16128 5 327 5.0E-80 T 13-09-2016 THL1_RS04115 0a521012c4cb182ebce5139c2c8c29d1 275 Hamap MF_01375 Phosphonoacetaldehyde hydrolase [phnX]. 1 275 136.951 T 13-09-2016 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 THL1_RS04115 0a521012c4cb182ebce5139c2c8c29d1 275 Gene3D G3DSA:1.10.150.240 28 102 5.5E-35 T 13-09-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 THL1_RS04115 0a521012c4cb182ebce5139c2c8c29d1 275 PANTHER PTHR18901:SF45 1 273 3.5E-114 T 13-09-2016 THL1_RS04115 0a521012c4cb182ebce5139c2c8c29d1 275 PANTHER PTHR18901 1 273 3.5E-114 T 13-09-2016 THL1_RS04115 0a521012c4cb182ebce5139c2c8c29d1 275 TIGRFAM TIGR01422 phosphonatase: phosphonoacetaldehyde hydrolase 9 260 5.5E-111 T 13-09-2016 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 THL1_RS04115 0a521012c4cb182ebce5139c2c8c29d1 275 Gene3D G3DSA:3.40.50.1000 8 27 2.7E-31 T 13-09-2016 IPR023214 HAD-like domain THL1_RS04115 0a521012c4cb182ebce5139c2c8c29d1 275 Gene3D G3DSA:3.40.50.1000 107 261 2.7E-31 T 13-09-2016 IPR023214 HAD-like domain THL1_RS04115 0a521012c4cb182ebce5139c2c8c29d1 275 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 77 206 6.0E-11 T 13-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THL1_RS04115 0a521012c4cb182ebce5139c2c8c29d1 275 SUPERFAMILY SSF56784 9 263 2.65E-56 T 13-09-2016 IPR023214 HAD-like domain THL1_RS01960 8411638415ca9671440a37a2f493cb8f 261 Pfam PF02633 Creatinine amidohydrolase 9 252 2.3E-53 T 13-09-2016 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167|UniPathway: UPA00071|UniPathway: UPA00275 THL1_RS01960 8411638415ca9671440a37a2f493cb8f 261 PANTHER PTHR35005 1 257 5.0E-35 T 13-09-2016 THL1_RS01960 8411638415ca9671440a37a2f493cb8f 261 PANTHER PTHR35005:SF1 1 257 5.0E-35 T 13-09-2016 THL1_RS01960 8411638415ca9671440a37a2f493cb8f 261 SUPERFAMILY SSF102215 4 256 3.14E-79 T 13-09-2016 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167|UniPathway: UPA00071|UniPathway: UPA00275 THL1_RS01960 8411638415ca9671440a37a2f493cb8f 261 TIGRFAM TIGR04448 creatininase: creatininase 9 257 1.2E-115 T 13-09-2016 IPR031034 Creatinine amidohydrolase GO:0006601|GO:0006602|GO:0047789 KEGG: 00330+3.5.2.10|UniPathway: UPA00274 THL1_RS01960 8411638415ca9671440a37a2f493cb8f 261 Gene3D G3DSA:3.40.50.10310 2 257 4.6E-82 T 13-09-2016 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167|UniPathway: UPA00071|UniPathway: UPA00275 THL1_RS21205 a174debb7f740c91d89f821f82d40f3a 328 Pfam PF12833 Helix-turn-helix domain 230 308 1.3E-23 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS21205 a174debb7f740c91d89f821f82d40f3a 328 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 291 307 4.8E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS21205 a174debb7f740c91d89f821f82d40f3a 328 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 276 291 4.8E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS21205 a174debb7f740c91d89f821f82d40f3a 328 Gene3D G3DSA:1.10.10.60 261 310 7.7E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21205 a174debb7f740c91d89f821f82d40f3a 328 SUPERFAMILY SSF52317 4 189 8.02E-25 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS21205 a174debb7f740c91d89f821f82d40f3a 328 SMART SM00342 224 307 1.4E-33 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS21205 a174debb7f740c91d89f821f82d40f3a 328 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 261 303 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS21205 a174debb7f740c91d89f821f82d40f3a 328 Gene3D G3DSA:3.40.50.880 79 211 4.3E-19 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS21205 a174debb7f740c91d89f821f82d40f3a 328 PANTHER PTHR11019 105 315 3.8E-97 T 13-09-2016 THL1_RS21205 a174debb7f740c91d89f821f82d40f3a 328 PANTHER PTHR11019:SF25 105 315 3.8E-97 T 13-09-2016 THL1_RS21205 a174debb7f740c91d89f821f82d40f3a 328 SUPERFAMILY SSF46689 207 258 1.43E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21205 a174debb7f740c91d89f821f82d40f3a 328 Gene3D G3DSA:1.10.10.60 212 260 1.4E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21205 a174debb7f740c91d89f821f82d40f3a 328 SUPERFAMILY SSF46689 260 311 1.48E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS00690 8abc12b3552f20ec5a0267c1403755ea 329 Gene3D G3DSA:3.40.50.300 2 237 1.1E-84 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00690 8abc12b3552f20ec5a0267c1403755ea 329 SUPERFAMILY SSF50331 235 321 1.62E-7 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS00690 8abc12b3552f20ec5a0267c1403755ea 329 PANTHER PTHR24220:SF123 4 276 1.5E-140 T 13-09-2016 THL1_RS00690 8abc12b3552f20ec5a0267c1403755ea 329 PANTHER PTHR24220 4 276 1.5E-140 T 13-09-2016 THL1_RS00690 8abc12b3552f20ec5a0267c1403755ea 329 SUPERFAMILY SSF52540 3 243 1.64E-87 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00690 8abc12b3552f20ec5a0267c1403755ea 329 Pfam PF12857 TOBE-like domain 269 321 2.1E-10 T 13-09-2016 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 THL1_RS00690 8abc12b3552f20ec5a0267c1403755ea 329 Pfam PF00005 ABC transporter 18 164 4.9E-37 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS00690 8abc12b3552f20ec5a0267c1403755ea 329 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 243 1.5E-120 T 13-09-2016 IPR005666 Sulphate transport system permease protein 1 GO:0006810|GO:0016020|GO:0042626 KEGG: 00920+3.6.3.25 THL1_RS00690 8abc12b3552f20ec5a0267c1403755ea 329 SMART SM00382 27 214 1.5E-20 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS00690 8abc12b3552f20ec5a0267c1403755ea 329 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS18430 9351d28e31ce9c0ba9a45e704c0a37ee 196 PANTHER PTHR30173 9 187 4.9E-69 T 13-09-2016 THL1_RS18430 9351d28e31ce9c0ba9a45e704c0a37ee 196 Gene3D G3DSA:1.10.1740.10 7 119 6.4E-29 T 13-09-2016 THL1_RS18430 9351d28e31ce9c0ba9a45e704c0a37ee 196 SUPERFAMILY SSF88659 103 187 1.53E-16 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS18430 9351d28e31ce9c0ba9a45e704c0a37ee 196 Pfam PF08281 Sigma-70, region 4 129 181 6.6E-12 T 13-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS18430 9351d28e31ce9c0ba9a45e704c0a37ee 196 Gene3D G3DSA:1.10.10.10 127 186 2.0E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS18430 9351d28e31ce9c0ba9a45e704c0a37ee 196 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 184 3.9E-29 T 13-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS18430 9351d28e31ce9c0ba9a45e704c0a37ee 196 Pfam PF04542 Sigma-70 region 2 27 94 1.9E-16 T 13-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS18430 9351d28e31ce9c0ba9a45e704c0a37ee 196 PANTHER PTHR30173:SF29 9 187 4.9E-69 T 13-09-2016 THL1_RS18430 9351d28e31ce9c0ba9a45e704c0a37ee 196 SUPERFAMILY SSF88946 7 107 1.04E-26 T 13-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS19585 0b802f194347738b2b8c5673be9bf8b9 101 PANTHER PTHR33495 14 100 2.7E-12 T 13-09-2016 THL1_RS19585 0b802f194347738b2b8c5673be9bf8b9 101 Gene3D G3DSA:3.30.750.24 10 100 1.0E-21 T 13-09-2016 IPR002645 STAS domain THL1_RS19585 0b802f194347738b2b8c5673be9bf8b9 101 SUPERFAMILY SSF52091 10 100 1.16E-22 T 13-09-2016 IPR002645 STAS domain THL1_RS19585 0b802f194347738b2b8c5673be9bf8b9 101 Pfam PF13466 STAS domain 18 94 9.1E-14 T 13-09-2016 IPR002645 STAS domain THL1_RS08900 bbcc48368d6cd8c738b26e00fcd280cb 241 SUPERFAMILY SSF52172 5 130 1.37E-39 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS08900 bbcc48368d6cd8c738b26e00fcd280cb 241 PANTHER PTHR26402:SF514 6 235 8.0E-127 T 13-09-2016 THL1_RS08900 bbcc48368d6cd8c738b26e00fcd280cb 241 SMART SM00862 156 232 5.9E-24 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS08900 bbcc48368d6cd8c738b26e00fcd280cb 241 Gene3D G3DSA:1.10.10.10 133 235 1.1E-31 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08900 bbcc48368d6cd8c738b26e00fcd280cb 241 Gene3D G3DSA:3.40.50.2300 3 125 1.5E-37 T 13-09-2016 THL1_RS08900 bbcc48368d6cd8c738b26e00fcd280cb 241 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 232 2.3E-23 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS08900 bbcc48368d6cd8c738b26e00fcd280cb 241 PANTHER PTHR26402 6 235 8.0E-127 T 13-09-2016 THL1_RS08900 bbcc48368d6cd8c738b26e00fcd280cb 241 SMART SM00448 6 116 6.6E-40 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS08900 bbcc48368d6cd8c738b26e00fcd280cb 241 Pfam PF00072 Response regulator receiver domain 8 117 3.5E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS08900 bbcc48368d6cd8c738b26e00fcd280cb 241 SUPERFAMILY SSF46894 133 233 4.54E-28 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS14510 e0ffb905dc8c8562125eccebd538dd17 649 SUPERFAMILY SSF46689 604 641 4.48E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS14510 e0ffb905dc8c8562125eccebd538dd17 649 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 361 374 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS14510 e0ffb905dc8c8562125eccebd538dd17 649 Gene3D G3DSA:3.40.50.300 336 510 1.5E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14510 e0ffb905dc8c8562125eccebd538dd17 649 SUPERFAMILY SSF55781 64 207 9.16E-11 T 13-09-2016 IPR029016 GAF domain-like THL1_RS14510 e0ffb905dc8c8562125eccebd538dd17 649 PANTHER PTHR32071 299 642 1.4E-133 T 13-09-2016 THL1_RS14510 e0ffb905dc8c8562125eccebd538dd17 649 Gene3D G3DSA:1.10.10.60 605 637 4.0E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS14510 e0ffb905dc8c8562125eccebd538dd17 649 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 424 439 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS14510 e0ffb905dc8c8562125eccebd538dd17 649 SMART SM00382 357 501 3.2E-12 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS14510 e0ffb905dc8c8562125eccebd538dd17 649 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 549 558 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS14510 e0ffb905dc8c8562125eccebd538dd17 649 Gene3D G3DSA:3.30.450.40 153 207 1.2E-5 T 13-09-2016 IPR029016 GAF domain-like THL1_RS14510 e0ffb905dc8c8562125eccebd538dd17 649 SUPERFAMILY SSF52540 340 579 1.49E-62 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14510 e0ffb905dc8c8562125eccebd538dd17 649 Pfam PF01590 GAF domain 87 204 1.3E-9 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS14510 e0ffb905dc8c8562125eccebd538dd17 649 Gene3D G3DSA:1.10.8.60 512 580 1.2E-17 T 13-09-2016 THL1_RS14510 e0ffb905dc8c8562125eccebd538dd17 649 Pfam PF00158 Sigma-54 interaction domain 340 502 1.8E-65 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS14510 e0ffb905dc8c8562125eccebd538dd17 649 PANTHER PTHR32071:SF5 299 642 1.4E-133 T 13-09-2016 THL1_RS14510 e0ffb905dc8c8562125eccebd538dd17 649 Pfam PF02954 Bacterial regulatory protein, Fis family 606 637 1.8E-10 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS08085 da84f08bdfad760e4cb385a69b2bffe4 335 PANTHER PTHR30578:SF0 13 326 7.3E-97 T 13-09-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 THL1_RS08085 da84f08bdfad760e4cb385a69b2bffe4 335 PANTHER PTHR30578 13 326 7.3E-97 T 13-09-2016 THL1_RS08085 da84f08bdfad760e4cb385a69b2bffe4 335 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 12 327 2.5E-105 T 13-09-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 THL1_RS08085 da84f08bdfad760e4cb385a69b2bffe4 335 Hamap MF_00462 Electron transport complex subunit RsxD [rsxD]. 1 334 23.247 T 13-09-2016 IPR011303 Electron transport complex, subunit RnfD/RsxD GO:0016021|GO:0022900 THL1_RS08085 da84f08bdfad760e4cb385a69b2bffe4 335 Pfam PF03116 NQR2, RnfD, RnfE family 12 327 2.1E-88 T 13-09-2016 IPR004338 NADH-quinone reductase NQR2/RnfD GO:0006810|GO:0016020 THL1_RS01405 daec33b62ee9e9cddbc42cf8bd42ef98 343 Pfam PF00850 Histone deacetylase domain 49 336 2.1E-58 T 13-09-2016 IPR023801 Histone deacetylase domain THL1_RS01405 daec33b62ee9e9cddbc42cf8bd42ef98 343 Gene3D G3DSA:3.40.800.20 3 336 4.2E-69 T 13-09-2016 IPR023801 Histone deacetylase domain THL1_RS01405 daec33b62ee9e9cddbc42cf8bd42ef98 343 PRINTS PR01270 Histone deacetylase superfamily signature 155 178 7.4E-15 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS01405 daec33b62ee9e9cddbc42cf8bd42ef98 343 PRINTS PR01270 Histone deacetylase superfamily signature 188 203 7.4E-15 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS01405 daec33b62ee9e9cddbc42cf8bd42ef98 343 PRINTS PR01270 Histone deacetylase superfamily signature 274 284 7.4E-15 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS01405 daec33b62ee9e9cddbc42cf8bd42ef98 343 SUPERFAMILY SSF52768 2 339 4.6E-83 T 13-09-2016 THL1_RS01405 daec33b62ee9e9cddbc42cf8bd42ef98 343 PANTHER PTHR10625:SF121 26 75 5.1E-98 T 13-09-2016 THL1_RS01405 daec33b62ee9e9cddbc42cf8bd42ef98 343 PANTHER PTHR10625:SF121 99 336 5.1E-98 T 13-09-2016 THL1_RS01405 daec33b62ee9e9cddbc42cf8bd42ef98 343 PANTHER PTHR10625 26 75 5.1E-98 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS01405 daec33b62ee9e9cddbc42cf8bd42ef98 343 PANTHER PTHR10625 99 336 5.1E-98 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS28450 45f3cfde3fce4479dd2d458ae33a67de 289 Gene3D G3DSA:1.20.120.220 100 287 7.5E-52 T 13-09-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 THL1_RS28450 45f3cfde3fce4479dd2d458ae33a67de 289 PANTHER PTHR11410:SF7 27 125 2.0E-92 T 13-09-2016 THL1_RS28450 45f3cfde3fce4479dd2d458ae33a67de 289 PANTHER PTHR11410:SF7 143 289 2.0E-92 T 13-09-2016 THL1_RS28450 45f3cfde3fce4479dd2d458ae33a67de 289 SUPERFAMILY SSF81336 99 282 3.66E-40 T 13-09-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 THL1_RS28450 45f3cfde3fce4479dd2d458ae33a67de 289 Pfam PF00119 ATP synthase A chain 52 282 1.6E-54 T 13-09-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 THL1_RS28450 45f3cfde3fce4479dd2d458ae33a67de 289 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 41 283 7.4E-43 T 13-09-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 THL1_RS28450 45f3cfde3fce4479dd2d458ae33a67de 289 Hamap MF_01393 ATP synthase subunit a [atpB]. 10 288 15.51 T 13-09-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 THL1_RS28450 45f3cfde3fce4479dd2d458ae33a67de 289 PANTHER PTHR11410 27 125 2.0E-92 T 13-09-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 THL1_RS28450 45f3cfde3fce4479dd2d458ae33a67de 289 PANTHER PTHR11410 143 289 2.0E-92 T 13-09-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 THL1_RS28450 45f3cfde3fce4479dd2d458ae33a67de 289 ProSitePatterns PS00449 ATP synthase a subunit signature. 217 226 - T 13-09-2016 IPR023011 ATPase, F0 complex, subunit A, active site THL1_RS08815 e06c7f95647195deaab3bf9d71a296a6 260 PANTHER PTHR10204 1 219 1.1E-112 T 13-09-2016 THL1_RS08815 e06c7f95647195deaab3bf9d71a296a6 260 Pfam PF02525 Flavodoxin-like fold 1 215 4.1E-57 T 13-09-2016 IPR003680 Flavodoxin-like fold THL1_RS08815 e06c7f95647195deaab3bf9d71a296a6 260 Gene3D G3DSA:3.40.50.360 1 234 1.9E-73 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS08815 e06c7f95647195deaab3bf9d71a296a6 260 SUPERFAMILY SSF52218 1 250 6.86E-72 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS08815 e06c7f95647195deaab3bf9d71a296a6 260 PANTHER PTHR10204:SF46 1 219 1.1E-112 T 13-09-2016 THL1_RS11035 c32e6c7aecf1d732c3836ac637972dc5 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 1.9E-7 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS11035 c32e6c7aecf1d732c3836ac637972dc5 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 1.9E-7 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS11035 c32e6c7aecf1d732c3836ac637972dc5 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 1.9E-7 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS11035 c32e6c7aecf1d732c3836ac637972dc5 287 SUPERFAMILY SSF53474 5 280 1.19E-43 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS11035 c32e6c7aecf1d732c3836ac637972dc5 287 PANTHER PTHR10992:SF909 5 286 2.0E-57 T 13-09-2016 THL1_RS11035 c32e6c7aecf1d732c3836ac637972dc5 287 PANTHER PTHR10992 5 286 2.0E-57 T 13-09-2016 THL1_RS11035 c32e6c7aecf1d732c3836ac637972dc5 287 Pfam PF00561 alpha/beta hydrolase fold 29 153 2.8E-16 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS11035 c32e6c7aecf1d732c3836ac637972dc5 287 Gene3D G3DSA:3.40.50.1820 4 278 5.6E-50 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS24945 65806eab07577bbb32d9e86da448f8e2 306 Pfam PF03466 LysR substrate binding domain 101 304 1.1E-27 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS24945 65806eab07577bbb32d9e86da448f8e2 306 SUPERFAMILY SSF53850 98 304 4.95E-27 T 13-09-2016 THL1_RS24945 65806eab07577bbb32d9e86da448f8e2 306 Gene3D G3DSA:1.10.10.10 15 96 3.5E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS24945 65806eab07577bbb32d9e86da448f8e2 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 76 2.6E-15 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS24945 65806eab07577bbb32d9e86da448f8e2 306 SUPERFAMILY SSF46785 16 101 1.77E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS24945 65806eab07577bbb32d9e86da448f8e2 306 Gene3D G3DSA:3.40.190.10 102 205 2.7E-15 T 13-09-2016 THL1_RS24945 65806eab07577bbb32d9e86da448f8e2 306 PANTHER PTHR30126:SF16 15 302 5.7E-78 T 13-09-2016 THL1_RS24945 65806eab07577bbb32d9e86da448f8e2 306 PANTHER PTHR30126 15 302 5.7E-78 T 13-09-2016 THL1_RS06725 c9f8e0ba86d4944622902a3958204c63 217 Gene3D G3DSA:1.20.1440.100 15 83 1.5E-19 T 13-09-2016 THL1_RS06725 c9f8e0ba86d4944622902a3958204c63 217 PANTHER PTHR10000:SF17 42 213 7.6E-92 T 13-09-2016 THL1_RS06725 c9f8e0ba86d4944622902a3958204c63 217 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 3 189 3.2E-31 T 13-09-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 THL1_RS06725 c9f8e0ba86d4944622902a3958204c63 217 Gene3D G3DSA:3.40.50.1000 84 217 1.4E-45 T 13-09-2016 IPR023214 HAD-like domain THL1_RS06725 c9f8e0ba86d4944622902a3958204c63 217 SUPERFAMILY SSF56784 2 211 3.86E-26 T 13-09-2016 IPR023214 HAD-like domain THL1_RS06725 c9f8e0ba86d4944622902a3958204c63 217 Pfam PF12710 haloacid dehalogenase-like hydrolase 4 187 5.4E-33 T 13-09-2016 THL1_RS06725 c9f8e0ba86d4944622902a3958204c63 217 PANTHER PTHR10000 42 213 7.6E-92 T 13-09-2016 THL1_RS06725 c9f8e0ba86d4944622902a3958204c63 217 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 3 201 6.4E-53 T 13-09-2016 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial THL1_RS11805 90f2b77b017905f55582ee8cbda6ae6c 136 Gene3D G3DSA:2.40.10.220 2 84 7.2E-4 T 13-09-2016 THL1_RS11805 90f2b77b017905f55582ee8cbda6ae6c 136 SUPERFAMILY SSF141371 2 86 7.65E-9 T 13-09-2016 THL1_RS11805 90f2b77b017905f55582ee8cbda6ae6c 136 Pfam PF07238 PilZ domain 2 87 3.9E-11 T 13-09-2016 IPR009875 PilZ domain GO:0035438 THL1_RS03745 322d1b561bfc35eb26894d9457146629 363 Gene3D G3DSA:3.20.20.70 29 361 5.7E-135 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS03745 322d1b561bfc35eb26894d9457146629 363 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 30 361 2.2E-133 T 13-09-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 THL1_RS03745 322d1b561bfc35eb26894d9457146629 363 PIRSF PIRSF001361 22 363 2.0E-144 T 13-09-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 THL1_RS03745 322d1b561bfc35eb26894d9457146629 363 PANTHER PTHR21225 28 361 6.9E-197 T 13-09-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 THL1_RS03745 322d1b561bfc35eb26894d9457146629 363 Pfam PF00793 DAHP synthetase I family 61 354 7.1E-81 T 13-09-2016 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 THL1_RS03745 322d1b561bfc35eb26894d9457146629 363 SUPERFAMILY SSF51569 29 360 1.99E-120 T 13-09-2016 THL1_RS03745 322d1b561bfc35eb26894d9457146629 363 PANTHER PTHR21225:SF5 28 361 6.9E-197 T 13-09-2016 THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 SMART SM00086 368 409 12.0 T 13-09-2016 IPR001610 PAC motif THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 SMART SM00086 235 278 2.7E-5 T 13-09-2016 IPR001610 PAC motif THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 159 284 4.0E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 Gene3D G3DSA:3.30.450.20 158 286 2.6E-34 T 13-09-2016 THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 PANTHER PTHR10799 267 411 2.5E-24 T 13-09-2016 THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 SMART SM00267 409 582 2.4E-59 T 13-09-2016 IPR000160 GGDEF domain THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 PANTHER PTHR10799:SF750 267 411 2.5E-24 T 13-09-2016 THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 Gene3D G3DSA:3.30.450.40 69 157 3.4E-5 T 13-09-2016 IPR029016 GAF domain-like THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 Gene3D G3DSA:3.30.70.270 422 581 8.7E-50 T 13-09-2016 THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 PANTHER PTHR10799:SF750 454 579 2.5E-24 T 13-09-2016 THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 SUPERFAMILY SSF55785 169 279 1.92E-18 T 13-09-2016 IPR000014 PAS domain THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 Pfam PF00990 Diguanylate cyclase, GGDEF domain 420 578 2.2E-42 T 13-09-2016 IPR000160 GGDEF domain THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 SUPERFAMILY SSF55785 310 417 1.57E-14 T 13-09-2016 IPR000014 PAS domain THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 SMART SM00065 13 156 0.0031 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 SMART SM00091 160 228 0.35 T 13-09-2016 IPR000014 PAS domain THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 SMART SM00091 290 362 4.2 T 13-09-2016 IPR000014 PAS domain THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 416 581 1.0E-47 T 13-09-2016 IPR000160 GGDEF domain THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 PANTHER PTHR10799 454 579 2.5E-24 T 13-09-2016 THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 Gene3D G3DSA:3.30.450.20 287 407 3.3E-15 T 13-09-2016 THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 Pfam PF08447 PAS fold 183 271 1.1E-22 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 Pfam PF08447 PAS fold 317 398 7.9E-12 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 SUPERFAMILY SSF55781 15 158 1.05E-10 T 13-09-2016 IPR029016 GAF domain-like THL1_RS08805 82c39a203f0fc2a92d9ae3a505ef9d9e 582 SUPERFAMILY SSF55073 425 580 1.49E-44 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS07115 45198739bcf6e96307c2891aead7b198 395 Gene3D G3DSA:2.40.110.10 129 225 1.1E-32 T 13-09-2016 THL1_RS07115 45198739bcf6e96307c2891aead7b198 395 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 223 5.4E-24 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS07115 45198739bcf6e96307c2891aead7b198 395 PANTHER PTHR10909 1 394 1.9E-134 T 13-09-2016 THL1_RS07115 45198739bcf6e96307c2891aead7b198 395 SUPERFAMILY SSF47203 236 386 7.68E-21 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS07115 45198739bcf6e96307c2891aead7b198 395 PANTHER PTHR10909:SF229 1 394 1.9E-134 T 13-09-2016 THL1_RS07115 45198739bcf6e96307c2891aead7b198 395 Gene3D G3DSA:1.20.140.10 226 392 1.1E-26 T 13-09-2016 THL1_RS07115 45198739bcf6e96307c2891aead7b198 395 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 385 2.0E-24 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS07115 45198739bcf6e96307c2891aead7b198 395 SUPERFAMILY SSF56645 5 247 3.14E-64 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS07115 45198739bcf6e96307c2891aead7b198 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 125 2.5E-20 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS07115 45198739bcf6e96307c2891aead7b198 395 Gene3D G3DSA:1.10.540.10 4 126 4.2E-25 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS02640 35b6e97de8baed2bd2f4655d32521f4f 338 SUPERFAMILY SSF53474 190 327 6.56E-13 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS02640 35b6e97de8baed2bd2f4655d32521f4f 338 SUPERFAMILY SSF53474 60 149 6.56E-13 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS02640 35b6e97de8baed2bd2f4655d32521f4f 338 Gene3D G3DSA:3.40.50.1820 80 132 5.0E-11 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS02640 35b6e97de8baed2bd2f4655d32521f4f 338 Gene3D G3DSA:3.40.50.1820 190 324 5.0E-11 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS02640 35b6e97de8baed2bd2f4655d32521f4f 338 Pfam PF12048 Protein of unknown function (DUF3530) 9 324 1.8E-99 T 13-09-2016 IPR022529 Protein of unknown function DUF3530 THL1_RS07840 3e0810a8bb312e5e5d2040f4950580ad 424 Pfam PF01266 FAD dependent oxidoreductase 10 399 1.3E-41 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS07840 3e0810a8bb312e5e5d2040f4950580ad 424 PANTHER PTHR13847 10 65 1.5E-38 T 13-09-2016 THL1_RS07840 3e0810a8bb312e5e5d2040f4950580ad 424 PANTHER PTHR13847:SF216 126 420 1.5E-38 T 13-09-2016 THL1_RS07840 3e0810a8bb312e5e5d2040f4950580ad 424 Gene3D G3DSA:3.30.9.10 143 192 8.7E-8 T 13-09-2016 THL1_RS07840 3e0810a8bb312e5e5d2040f4950580ad 424 Gene3D G3DSA:3.30.9.10 273 350 8.7E-8 T 13-09-2016 THL1_RS07840 3e0810a8bb312e5e5d2040f4950580ad 424 PANTHER PTHR13847 126 420 1.5E-38 T 13-09-2016 THL1_RS07840 3e0810a8bb312e5e5d2040f4950580ad 424 SUPERFAMILY SSF54373 275 360 3.27E-10 T 13-09-2016 THL1_RS07840 3e0810a8bb312e5e5d2040f4950580ad 424 SUPERFAMILY SSF51905 120 273 9.58E-39 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07840 3e0810a8bb312e5e5d2040f4950580ad 424 SUPERFAMILY SSF51905 9 59 9.58E-39 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07840 3e0810a8bb312e5e5d2040f4950580ad 424 SUPERFAMILY SSF51905 360 418 9.58E-39 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07840 3e0810a8bb312e5e5d2040f4950580ad 424 Gene3D G3DSA:3.50.50.60 360 417 3.9E-43 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07840 3e0810a8bb312e5e5d2040f4950580ad 424 Gene3D G3DSA:3.50.50.60 193 272 3.9E-43 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07840 3e0810a8bb312e5e5d2040f4950580ad 424 Gene3D G3DSA:3.50.50.60 113 135 3.9E-43 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07840 3e0810a8bb312e5e5d2040f4950580ad 424 Gene3D G3DSA:3.50.50.60 4 63 3.9E-43 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07840 3e0810a8bb312e5e5d2040f4950580ad 424 PANTHER PTHR13847:SF216 10 65 1.5E-38 T 13-09-2016 THL1_RS09700 8840fcf52e1ee92cf13ff28cae05fc84 391 SUPERFAMILY SSF51604 127 387 3.54E-69 T 13-09-2016 IPR029065 Enolase C-terminal domain-like THL1_RS09700 8840fcf52e1ee92cf13ff28cae05fc84 391 SUPERFAMILY SSF54826 1 143 1.13E-33 T 13-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THL1_RS09700 8840fcf52e1ee92cf13ff28cae05fc84 391 SMART SM00922 159 262 5.8E-22 T 13-09-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal THL1_RS09700 8840fcf52e1ee92cf13ff28cae05fc84 391 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 39 139 4.0E-20 T 13-09-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain THL1_RS09700 8840fcf52e1ee92cf13ff28cae05fc84 391 Gene3D G3DSA:3.20.20.120 145 379 9.0E-71 T 13-09-2016 IPR029065 Enolase C-terminal domain-like THL1_RS09700 8840fcf52e1ee92cf13ff28cae05fc84 391 Gene3D G3DSA:3.30.390.10 1 144 3.9E-50 T 13-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THL1_RS09700 8840fcf52e1ee92cf13ff28cae05fc84 391 PANTHER PTHR13794 10 391 5.7E-190 T 13-09-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 THL1_RS09700 8840fcf52e1ee92cf13ff28cae05fc84 391 PANTHER PTHR13794:SF50 10 391 5.7E-190 T 13-09-2016 THL1_RS09700 8840fcf52e1ee92cf13ff28cae05fc84 391 Pfam PF13378 Enolase C-terminal domain-like 164 382 5.6E-55 T 13-09-2016 IPR029065 Enolase C-terminal domain-like THL1_RS01050 0f61fa9139f3b68adeaee8681adc8b8b 170 PRINTS PR00070 Dihydrofolate reductase signature 102 116 1.2E-15 T 13-09-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 THL1_RS01050 0f61fa9139f3b68adeaee8681adc8b8b 170 PRINTS PR00070 Dihydrofolate reductase signature 32 40 1.2E-15 T 13-09-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 THL1_RS01050 0f61fa9139f3b68adeaee8681adc8b8b 170 PRINTS PR00070 Dihydrofolate reductase signature 18 28 1.2E-15 T 13-09-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 THL1_RS01050 0f61fa9139f3b68adeaee8681adc8b8b 170 PRINTS PR00070 Dihydrofolate reductase signature 45 56 1.2E-15 T 13-09-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 THL1_RS01050 0f61fa9139f3b68adeaee8681adc8b8b 170 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 18 40 - T 13-09-2016 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 THL1_RS01050 0f61fa9139f3b68adeaee8681adc8b8b 170 SUPERFAMILY SSF53597 7 170 2.24E-55 T 13-09-2016 IPR024072 Dihydrofolate reductase-like domain THL1_RS01050 0f61fa9139f3b68adeaee8681adc8b8b 170 PANTHER PTHR22778:SF16 1 170 2.6E-46 T 13-09-2016 THL1_RS01050 0f61fa9139f3b68adeaee8681adc8b8b 170 Pfam PF00186 Dihydrofolate reductase 7 169 6.4E-56 T 13-09-2016 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 THL1_RS01050 0f61fa9139f3b68adeaee8681adc8b8b 170 PANTHER PTHR22778 1 170 2.6E-46 T 13-09-2016 THL1_RS01050 0f61fa9139f3b68adeaee8681adc8b8b 170 PIRSF PIRSF000194 1 170 4.2E-61 T 13-09-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 THL1_RS01050 0f61fa9139f3b68adeaee8681adc8b8b 170 Gene3D G3DSA:3.40.430.10 2 170 2.8E-59 T 13-09-2016 IPR024072 Dihydrofolate reductase-like domain THL1_RS07105 71d0d2d50b3f45922cfa334a9723c7a7 107 SMART SM00530 19 73 1.6E-5 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS07105 71d0d2d50b3f45922cfa334a9723c7a7 107 SUPERFAMILY SSF47413 12 75 6.17E-9 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS07105 71d0d2d50b3f45922cfa334a9723c7a7 107 Gene3D G3DSA:1.10.260.40 19 59 3.2E-9 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS07105 71d0d2d50b3f45922cfa334a9723c7a7 107 Pfam PF01381 Helix-turn-helix 20 53 5.4E-7 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS04525 71dfe873bc56baf4b647a710d787bd55 372 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS04525 71dfe873bc56baf4b647a710d787bd55 372 PANTHER PTHR24220 11 256 5.4E-129 T 13-09-2016 THL1_RS04525 71dfe873bc56baf4b647a710d787bd55 372 Gene3D G3DSA:3.40.50.300 10 243 7.7E-79 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04525 71dfe873bc56baf4b647a710d787bd55 372 SMART SM00382 34 219 2.6E-14 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS04525 71dfe873bc56baf4b647a710d787bd55 372 PANTHER PTHR24220:SF150 11 256 5.4E-129 T 13-09-2016 THL1_RS04525 71dfe873bc56baf4b647a710d787bd55 372 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 41 366 3.1E-112 T 13-09-2016 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 THL1_RS04525 71dfe873bc56baf4b647a710d787bd55 372 SUPERFAMILY SSF50331 244 367 4.36E-15 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS04525 71dfe873bc56baf4b647a710d787bd55 372 Pfam PF08402 TOBE domain 289 368 4.4E-12 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS04525 71dfe873bc56baf4b647a710d787bd55 372 Pfam PF00005 ABC transporter 26 169 2.2E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS04525 71dfe873bc56baf4b647a710d787bd55 372 SUPERFAMILY SSF52540 10 249 9.29E-84 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22845 ed42848439468b9129a3367c177914df 166 SUPERFAMILY SSF52949 2 165 4.88E-64 T 13-09-2016 THL1_RS22845 ed42848439468b9129a3367c177914df 166 Gene3D G3DSA:3.40.220.10 2 165 8.3E-70 T 13-09-2016 THL1_RS22845 ed42848439468b9129a3367c177914df 166 SMART SM00506 2 131 3.4E-54 T 13-09-2016 IPR002589 Macro domain THL1_RS22845 ed42848439468b9129a3367c177914df 166 Pfam PF01661 Macro domain 19 131 7.8E-46 T 13-09-2016 IPR002589 Macro domain THL1_RS22845 ed42848439468b9129a3367c177914df 166 PANTHER PTHR11106 3 166 3.8E-86 T 13-09-2016 THL1_RS02400 79245920b4e8de4b739d094a1462fd17 414 SUPERFAMILY SSF53383 9 398 1.33E-86 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS02400 79245920b4e8de4b739d094a1462fd17 414 PANTHER PTHR14084 6 407 2.8E-136 T 13-09-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 THL1_RS02400 79245920b4e8de4b739d094a1462fd17 414 TIGRFAM TIGR01814 kynureninase: kynureninase 13 398 5.7E-96 T 13-09-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 THL1_RS02400 79245920b4e8de4b739d094a1462fd17 414 Gene3D G3DSA:3.90.1150.10 256 414 1.0E-56 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS02400 79245920b4e8de4b739d094a1462fd17 414 Hamap MF_01970 Kynureninase [kynU]. 2 397 33.344 T 13-09-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 THL1_RS02400 79245920b4e8de4b739d094a1462fd17 414 Gene3D G3DSA:3.40.640.10 35 255 5.3E-22 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS02400 79245920b4e8de4b739d094a1462fd17 414 PIRSF PIRSF038800 4 405 2.5E-144 T 13-09-2016 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|UniPathway: UPA00253|UniPathway: UPA00334 THL1_RS02400 79245920b4e8de4b739d094a1462fd17 414 Pfam PF00266 Aminotransferase class-V 79 351 1.4E-21 T 13-09-2016 IPR000192 Aminotransferase class V domain THL1_RS19085 1c728e72f3077fdc5c8e907436e96dcf 496 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 264 271 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS19085 1c728e72f3077fdc5c8e907436e96dcf 496 Pfam PF00171 Aldehyde dehydrogenase family 30 490 4.4E-167 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS19085 1c728e72f3077fdc5c8e907436e96dcf 496 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 293 304 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS19085 1c728e72f3077fdc5c8e907436e96dcf 496 SUPERFAMILY SSF53720 15 494 2.88E-166 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS19085 1c728e72f3077fdc5c8e907436e96dcf 496 Gene3D G3DSA:3.40.309.10 279 466 2.4E-66 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS19085 1c728e72f3077fdc5c8e907436e96dcf 496 Gene3D G3DSA:3.40.605.10 19 278 7.1E-93 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS19085 1c728e72f3077fdc5c8e907436e96dcf 496 PANTHER PTHR11699 1 496 0.0 T 13-09-2016 THL1_RS19085 1c728e72f3077fdc5c8e907436e96dcf 496 PANTHER PTHR11699:SF210 1 496 0.0 T 13-09-2016 THL1_RS27305 02c36254d50e8884822652d0dc891068 322 SUPERFAMILY SSF54292 2 79 9.31E-19 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS27305 02c36254d50e8884822652d0dc891068 322 Gene3D G3DSA:2.40.30.10 93 186 5.4E-18 T 13-09-2016 THL1_RS27305 02c36254d50e8884822652d0dc891068 322 Pfam PF00175 Oxidoreductase NAD-binding domain 197 296 6.8E-13 T 13-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THL1_RS27305 02c36254d50e8884822652d0dc891068 322 PANTHER PTHR19370 31 316 8.5E-73 T 13-09-2016 THL1_RS27305 02c36254d50e8884822652d0dc891068 322 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 4 68 1.9E-10 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS27305 02c36254d50e8884822652d0dc891068 322 PRINTS PR00410 Phenol hydroxylase reductase family signature 196 215 9.4E-10 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS27305 02c36254d50e8884822652d0dc891068 322 PRINTS PR00410 Phenol hydroxylase reductase family signature 138 145 9.4E-10 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS27305 02c36254d50e8884822652d0dc891068 322 PRINTS PR00410 Phenol hydroxylase reductase family signature 221 230 9.4E-10 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS27305 02c36254d50e8884822652d0dc891068 322 PRINTS PR00410 Phenol hydroxylase reductase family signature 284 292 9.4E-10 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS27305 02c36254d50e8884822652d0dc891068 322 PRINTS PR00410 Phenol hydroxylase reductase family signature 122 134 9.4E-10 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS27305 02c36254d50e8884822652d0dc891068 322 SUPERFAMILY SSF63380 93 186 2.0E-15 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS27305 02c36254d50e8884822652d0dc891068 322 Gene3D G3DSA:3.10.20.30 2 78 2.1E-19 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS27305 02c36254d50e8884822652d0dc891068 322 PANTHER PTHR19370:SF68 31 316 8.5E-73 T 13-09-2016 THL1_RS27305 02c36254d50e8884822652d0dc891068 322 SUPERFAMILY SSF52343 192 317 9.69E-31 T 13-09-2016 THL1_RS27305 02c36254d50e8884822652d0dc891068 322 Gene3D G3DSA:3.40.50.80 191 317 1.6E-30 T 13-09-2016 THL1_RS12050 dcbeac464a3a18884a5b75ff758b822c 152 SUPERFAMILY SSF54292 2 86 4.98E-27 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS12050 dcbeac464a3a18884a5b75ff758b822c 152 Gene3D G3DSA:3.10.20.30 2 73 7.4E-29 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS12050 dcbeac464a3a18884a5b75ff758b822c 152 SUPERFAMILY SSF47741 83 150 1.7E-29 T 13-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 THL1_RS12050 dcbeac464a3a18884a5b75ff758b822c 152 Pfam PF01799 [2Fe-2S] binding domain 72 144 1.5E-24 T 13-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 THL1_RS12050 dcbeac464a3a18884a5b75ff758b822c 152 PANTHER PTHR11908:SF66 1 134 1.2E-29 T 13-09-2016 THL1_RS12050 dcbeac464a3a18884a5b75ff758b822c 152 Gene3D G3DSA:1.10.150.120 74 149 4.7E-29 T 13-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 THL1_RS12050 dcbeac464a3a18884a5b75ff758b822c 152 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 13-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THL1_RS12050 dcbeac464a3a18884a5b75ff758b822c 152 PANTHER PTHR11908 1 134 1.2E-29 T 13-09-2016 THL1_RS12050 dcbeac464a3a18884a5b75ff758b822c 152 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 59 7.2E-9 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS00550 7a8b89aef668ad50e4894242e80cddca 393 PANTHER PTHR10909:SF307 1 392 1.3E-266 T 13-09-2016 THL1_RS00550 7a8b89aef668ad50e4894242e80cddca 393 SUPERFAMILY SSF56645 7 238 4.97E-76 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS00550 7a8b89aef668ad50e4894242e80cddca 393 PANTHER PTHR10909 1 392 1.3E-266 T 13-09-2016 THL1_RS00550 7a8b89aef668ad50e4894242e80cddca 393 Gene3D G3DSA:1.20.140.10 227 388 6.2E-44 T 13-09-2016 THL1_RS00550 7a8b89aef668ad50e4894242e80cddca 393 SUPERFAMILY SSF47203 243 390 4.67E-42 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS00550 7a8b89aef668ad50e4894242e80cddca 393 Gene3D G3DSA:1.10.540.10 5 134 3.2E-41 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS00550 7a8b89aef668ad50e4894242e80cddca 393 Gene3D G3DSA:2.40.110.10 135 226 4.0E-32 T 13-09-2016 THL1_RS00550 7a8b89aef668ad50e4894242e80cddca 393 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 136 227 2.3E-21 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS00550 7a8b89aef668ad50e4894242e80cddca 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 20 132 1.1E-34 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS00550 7a8b89aef668ad50e4894242e80cddca 393 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 385 5.7E-28 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS00550 7a8b89aef668ad50e4894242e80cddca 393 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 345 364 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS16165 056b3af812853aee525952b633948250 278 Pfam PF09684 Phage tail protein (Tail_P2_I) 5 146 5.9E-42 T 13-09-2016 IPR006521 Tail protein I THL1_RS16165 056b3af812853aee525952b633948250 278 TIGRFAM TIGR01634 tail_P2_I: phage tail protein I 5 117 9.3E-43 T 13-09-2016 IPR006521 Tail protein I THL1_RS08075 48c480129ad39f3510341dbabaa1457f 190 PIRSF PIRSF006102 5 190 1.1E-18 T 13-09-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 THL1_RS08075 48c480129ad39f3510341dbabaa1457f 190 Pfam PF02508 Rnf-Nqr subunit, membrane protein 9 175 7.3E-11 T 13-09-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 THL1_RS26700 234e590a5c7e732de01ad5580dfa6f73 91 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 13-09-2016 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 THL1_RS26700 234e590a5c7e732de01ad5580dfa6f73 91 Pfam PF00462 Glutaredoxin 4 63 2.5E-22 T 13-09-2016 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 THL1_RS26700 234e590a5c7e732de01ad5580dfa6f73 91 SUPERFAMILY SSF52833 2 83 3.22E-29 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS26700 234e590a5c7e732de01ad5580dfa6f73 91 PRINTS PR00160 Glutaredoxin signature 4 22 4.7E-15 T 13-09-2016 IPR014025 Glutaredoxin subgroup THL1_RS26700 234e590a5c7e732de01ad5580dfa6f73 91 PRINTS PR00160 Glutaredoxin signature 46 59 4.7E-15 T 13-09-2016 IPR014025 Glutaredoxin subgroup THL1_RS26700 234e590a5c7e732de01ad5580dfa6f73 91 PRINTS PR00160 Glutaredoxin signature 60 73 4.7E-15 T 13-09-2016 IPR014025 Glutaredoxin subgroup THL1_RS26700 234e590a5c7e732de01ad5580dfa6f73 91 PANTHER PTHR10168 4 84 2.1E-27 T 13-09-2016 THL1_RS26700 234e590a5c7e732de01ad5580dfa6f73 91 Gene3D G3DSA:3.40.30.10 2 84 3.8E-29 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS26700 234e590a5c7e732de01ad5580dfa6f73 91 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 82 1.3E-35 T 13-09-2016 IPR011900 Glutaredoxin, GrxC GO:0045454 THL1_RS04900 f7dca901c766dd975e9145a1690809a9 165 Pfam PF14341 PilX N-terminal 11 59 3.3E-6 T 13-09-2016 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain THL1_RS18045 54a7f8e4a0b7b71dd6cdb17f55466b4f 240 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 3 231 4.4E-103 T 13-09-2016 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54|UniPathway: UPA00359 THL1_RS18045 54a7f8e4a0b7b71dd6cdb17f55466b4f 240 Gene3D G3DSA:3.60.21.10 2 124 3.8E-20 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS18045 54a7f8e4a0b7b71dd6cdb17f55466b4f 240 Gene3D G3DSA:3.60.21.10 172 202 3.8E-20 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS18045 54a7f8e4a0b7b71dd6cdb17f55466b4f 240 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 240 122.885 T 13-09-2016 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54|UniPathway: UPA00359 THL1_RS18045 54a7f8e4a0b7b71dd6cdb17f55466b4f 240 SUPERFAMILY SSF56300 2 220 2.64E-27 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS18045 54a7f8e4a0b7b71dd6cdb17f55466b4f 240 Pfam PF00149 Calcineurin-like phosphoesterase 2 198 5.5E-9 T 13-09-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 THL1_RS18045 54a7f8e4a0b7b71dd6cdb17f55466b4f 240 PANTHER PTHR34990 3 234 4.4E-108 T 13-09-2016 THL1_RS18045 54a7f8e4a0b7b71dd6cdb17f55466b4f 240 PANTHER PTHR34990:SF1 3 234 4.4E-108 T 13-09-2016 THL1_RS20160 6764fe7dd7edc7cc534db6d643158071 175 Gene3D G3DSA:3.30.530.20 27 175 3.8E-13 T 13-09-2016 IPR023393 START-like domain THL1_RS20160 6764fe7dd7edc7cc534db6d643158071 175 SUPERFAMILY SSF55961 21 175 7.15E-25 T 13-09-2016 THL1_RS20160 6764fe7dd7edc7cc534db6d643158071 175 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 27 174 5.9E-22 T 13-09-2016 IPR019587 Polyketide cyclase/dehydrase THL1_RS05600 14db5585824ddd6b7bae03ef318a9521 315 PANTHER PTHR11265:SF0 2 315 2.7E-148 T 13-09-2016 THL1_RS05600 14db5585824ddd6b7bae03ef318a9521 315 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 9 314 38.707 T 13-09-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS05600 14db5585824ddd6b7bae03ef318a9521 315 Gene3D G3DSA:1.10.150.170 116 219 5.8E-35 T 13-09-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS05600 14db5585824ddd6b7bae03ef318a9521 315 SUPERFAMILY SSF53335 9 117 3.12E-47 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS05600 14db5585824ddd6b7bae03ef318a9521 315 SUPERFAMILY SSF53335 217 314 3.12E-47 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS05600 14db5585824ddd6b7bae03ef318a9521 315 PANTHER PTHR11265 2 315 2.7E-148 T 13-09-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS05600 14db5585824ddd6b7bae03ef318a9521 315 Gene3D G3DSA:3.40.50.150 9 114 1.3E-50 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS05600 14db5585824ddd6b7bae03ef318a9521 315 Gene3D G3DSA:3.40.50.150 220 314 1.3E-50 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS05600 14db5585824ddd6b7bae03ef318a9521 315 SUPERFAMILY SSF81799 118 217 1.23E-33 T 13-09-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS05600 14db5585824ddd6b7bae03ef318a9521 315 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 5 313 8.0E-113 T 13-09-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS05600 14db5585824ddd6b7bae03ef318a9521 315 PIRSF PIRSF004486 3 315 3.2E-99 T 13-09-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS05600 14db5585824ddd6b7bae03ef318a9521 315 Pfam PF01795 MraW methylase family 7 313 3.6E-110 T 13-09-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS15465 df0c8915bd144dde2ff31ce45292a381 477 PANTHER PTHR30624:SF10 10 477 2.1E-159 T 13-09-2016 THL1_RS15465 df0c8915bd144dde2ff31ce45292a381 477 PANTHER PTHR30624 10 477 2.1E-159 T 13-09-2016 THL1_RS15465 df0c8915bd144dde2ff31ce45292a381 477 Pfam PF01523 Putative modulator of DNA gyrase 21 321 9.7E-38 T 13-09-2016 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS15465 df0c8915bd144dde2ff31ce45292a381 477 SUPERFAMILY SSF111283 5 472 2.75E-87 T 13-09-2016 THL1_RS16460 2c1ea6b5fd9dfbd38d4708f0c164beeb 311 Gene3D G3DSA:3.40.1350.10 12 135 1.5E-6 T 13-09-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 THL1_RS16460 2c1ea6b5fd9dfbd38d4708f0c164beeb 311 Pfam PF04471 Restriction endonuclease 12 133 1.8E-5 T 13-09-2016 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 THL1_RS20440 0b3d7f6e4e6faa7f65e21fe735050e05 501 Gene3D G3DSA:3.40.605.10 7 264 2.5E-101 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS20440 0b3d7f6e4e6faa7f65e21fe735050e05 501 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 8 484 3.1E-224 T 13-09-2016 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373 THL1_RS20440 0b3d7f6e4e6faa7f65e21fe735050e05 501 SUPERFAMILY SSF53720 5 486 5.37E-148 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS20440 0b3d7f6e4e6faa7f65e21fe735050e05 501 Pfam PF00171 Aldehyde dehydrogenase family 16 480 1.7E-140 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS20440 0b3d7f6e4e6faa7f65e21fe735050e05 501 PANTHER PTHR11699 1 488 0.0 T 13-09-2016 THL1_RS20440 0b3d7f6e4e6faa7f65e21fe735050e05 501 PANTHER PTHR11699:SF181 1 488 0.0 T 13-09-2016 THL1_RS20440 0b3d7f6e4e6faa7f65e21fe735050e05 501 Gene3D G3DSA:3.40.309.10 265 445 3.6E-65 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS07685 2187353a053f080275275cb6b6a43d07 417 Gene3D G3DSA:2.40.160.10 29 417 9.6E-145 T 13-09-2016 IPR023614 Porin domain THL1_RS07685 2187353a053f080275275cb6b6a43d07 417 Pfam PF03573 outer membrane porin, OprD family 24 415 5.2E-152 T 13-09-2016 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 THL1_RS07685 2187353a053f080275275cb6b6a43d07 417 PANTHER PTHR34596 1 417 6.4E-151 T 13-09-2016 THL1_RS18755 187e722a6ca592de9f815881d5cd70ad 481 PANTHER PTHR12526 160 291 1.7E-107 T 13-09-2016 THL1_RS18755 187e722a6ca592de9f815881d5cd70ad 481 PANTHER PTHR12526 354 471 1.7E-107 T 13-09-2016 THL1_RS18755 187e722a6ca592de9f815881d5cd70ad 481 PANTHER PTHR12526:SF387 160 291 1.7E-107 T 13-09-2016 THL1_RS18755 187e722a6ca592de9f815881d5cd70ad 481 PANTHER PTHR12526:SF387 354 471 1.7E-107 T 13-09-2016 THL1_RS18755 187e722a6ca592de9f815881d5cd70ad 481 Pfam PF01050 Mannose-6-phosphate isomerase 317 467 8.9E-74 T 13-09-2016 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882|UniPathway: UPA00126 THL1_RS18755 187e722a6ca592de9f815881d5cd70ad 481 SUPERFAMILY SSF51182 187 471 8.22E-85 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS18755 187e722a6ca592de9f815881d5cd70ad 481 Pfam PF00483 Nucleotidyl transferase 3 287 1.3E-72 T 13-09-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 THL1_RS18755 187e722a6ca592de9f815881d5cd70ad 481 SUPERFAMILY SSF53448 1 284 5.86E-69 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS18755 187e722a6ca592de9f815881d5cd70ad 481 Gene3D G3DSA:3.90.550.10 1 273 4.5E-92 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS18755 187e722a6ca592de9f815881d5cd70ad 481 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 1 471 1.0E-222 T 13-09-2016 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882|UniPathway: UPA00126 THL1_RS18755 187e722a6ca592de9f815881d5cd70ad 481 Gene3D G3DSA:2.60.120.10 360 472 9.8E-46 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS15625 a76ba43a8265da69e2dcebe4c0ca578c 566 Gene3D G3DSA:2.30.38.10 374 447 4.7E-27 T 13-09-2016 THL1_RS15625 a76ba43a8265da69e2dcebe4c0ca578c 566 ProSitePatterns PS00455 Putative AMP-binding domain signature. 206 217 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS15625 a76ba43a8265da69e2dcebe4c0ca578c 566 Gene3D G3DSA:3.40.50.980 221 366 2.9E-49 T 13-09-2016 THL1_RS15625 a76ba43a8265da69e2dcebe4c0ca578c 566 Gene3D G3DSA:3.40.50.980 18 220 8.4E-40 T 13-09-2016 THL1_RS15625 a76ba43a8265da69e2dcebe4c0ca578c 566 Pfam PF13193 AMP-binding enzyme C-terminal domain 465 540 3.5E-16 T 13-09-2016 IPR025110 AMP-binding enzyme C-terminal domain THL1_RS15625 a76ba43a8265da69e2dcebe4c0ca578c 566 Gene3D G3DSA:3.30.300.30 453 553 2.0E-31 T 13-09-2016 THL1_RS15625 a76ba43a8265da69e2dcebe4c0ca578c 566 SUPERFAMILY SSF56801 13 552 1.44E-158 T 13-09-2016 THL1_RS15625 a76ba43a8265da69e2dcebe4c0ca578c 566 Pfam PF00501 AMP-binding enzyme 24 456 5.0E-103 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS15625 a76ba43a8265da69e2dcebe4c0ca578c 566 PANTHER PTHR24095 19 554 1.1E-193 T 13-09-2016 THL1_RS05320 f09846152940d17b9ce5e5c119ab87f0 1264 Pfam PF13502 AsmA-like C-terminal region 1008 1253 8.0E-49 T 13-09-2016 IPR032712 AsmA-like, C-terminal THL1_RS05320 f09846152940d17b9ce5e5c119ab87f0 1264 Pfam PF13116 Protein of unknown function 506 787 5.9E-46 T 13-09-2016 IPR025263 Domain of unknown function DUF3971 THL1_RS05320 f09846152940d17b9ce5e5c119ab87f0 1264 PANTHER PTHR38690 1 1263 3.2E-290 T 13-09-2016 THL1_RS05320 f09846152940d17b9ce5e5c119ab87f0 1264 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 3 1263 0.0 T 13-09-2016 IPR011836 Conserved hypothetical protein CHP02099 THL1_RS04930 364042065e284f53416181591ed6fae4 343 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 27 1.4E-5 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS04930 364042065e284f53416181591ed6fae4 343 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS04930 364042065e284f53416181591ed6fae4 343 Pfam PF16074 Type IV Pilus-assembly protein W 220 340 4.7E-18 T 13-09-2016 IPR032092 Type IV Pilus-assembly protein W GO:0043683 THL1_RS04930 364042065e284f53416181591ed6fae4 343 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 1 26 2.1E-8 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS04130 354bcf11d4060c9e68cf3676b4c436b4 290 Gene3D G3DSA:1.10.10.10 5 82 2.1E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS04130 354bcf11d4060c9e68cf3676b4c436b4 290 Pfam PF03466 LysR substrate binding domain 91 287 1.1E-40 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS04130 354bcf11d4060c9e68cf3676b4c436b4 290 Gene3D G3DSA:3.40.190.10 105 174 6.9E-15 T 13-09-2016 THL1_RS04130 354bcf11d4060c9e68cf3676b4c436b4 290 SUPERFAMILY SSF46785 4 98 3.16E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS04130 354bcf11d4060c9e68cf3676b4c436b4 290 PANTHER PTHR30126:SF17 3 285 1.6E-136 T 13-09-2016 THL1_RS04130 354bcf11d4060c9e68cf3676b4c436b4 290 Gene3D G3DSA:3.40.190.10 175 257 5.3E-26 T 13-09-2016 THL1_RS04130 354bcf11d4060c9e68cf3676b4c436b4 290 SUPERFAMILY SSF53850 92 288 4.79E-39 T 13-09-2016 THL1_RS04130 354bcf11d4060c9e68cf3676b4c436b4 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.3E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS04130 354bcf11d4060c9e68cf3676b4c436b4 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.3E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS04130 354bcf11d4060c9e68cf3676b4c436b4 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.3E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS04130 354bcf11d4060c9e68cf3676b4c436b4 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 1.9E-22 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS04130 354bcf11d4060c9e68cf3676b4c436b4 290 PANTHER PTHR30126 3 285 1.6E-136 T 13-09-2016 THL1_RS04130 354bcf11d4060c9e68cf3676b4c436b4 290 TIGRFAM TIGR03339 phn_lysR: aminoethylphosphonate catabolism associated LysR family transcriptional regulator 7 285 8.8E-113 T 13-09-2016 IPR017724 Aminoethylphosphonate utilisation-associated transcription regulator, LysR-type THL1_RS05150 fddfc226004a34f771b1a453157b4e0f 236 SUPERFAMILY SSF161098 18 231 1.57E-41 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS05150 fddfc226004a34f771b1a453157b4e0f 236 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 231 5.2E-26 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS05150 fddfc226004a34f771b1a453157b4e0f 236 PANTHER PTHR30133 6 234 9.5E-68 T 13-09-2016 THL1_RS05150 fddfc226004a34f771b1a453157b4e0f 236 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 18 124 3.7E-18 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS05150 fddfc226004a34f771b1a453157b4e0f 236 Gene3D G3DSA:1.10.3720.10 18 232 6.4E-45 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00930 3ad22c6bc8e4e10b9d51123c48e9d738 270 SMART SM00382 41 215 3.3E-16 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS00930 3ad22c6bc8e4e10b9d51123c48e9d738 270 SUPERFAMILY SSF52540 17 217 1.93E-63 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00930 3ad22c6bc8e4e10b9d51123c48e9d738 270 Gene3D G3DSA:3.40.50.300 15 216 1.6E-62 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00930 3ad22c6bc8e4e10b9d51123c48e9d738 270 PANTHER PTHR24220:SF365 18 262 1.2E-155 T 13-09-2016 IPR017875 Aliphatic sulfonates import ATP-binding protein SsuB GO:0005215|GO:0005524|GO:0005886|GO:0006810 THL1_RS00930 3ad22c6bc8e4e10b9d51123c48e9d738 270 Pfam PF00005 ABC transporter 32 165 1.2E-29 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS00930 3ad22c6bc8e4e10b9d51123c48e9d738 270 PANTHER PTHR24220 18 262 1.2E-155 T 13-09-2016 THL1_RS00930 3ad22c6bc8e4e10b9d51123c48e9d738 270 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS08070 7bb5bf3ad614e7ececa5dbbc3eaa6ecf 212 SMART SM00478 38 185 4.3E-59 T 13-09-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 THL1_RS08070 7bb5bf3ad614e7ececa5dbbc3eaa6ecf 212 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 4.5E-4 T 13-09-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: REACT_216 THL1_RS08070 7bb5bf3ad614e7ececa5dbbc3eaa6ecf 212 Gene3D G3DSA:1.10.1670.10 123 208 1.4E-36 T 13-09-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal THL1_RS08070 7bb5bf3ad614e7ececa5dbbc3eaa6ecf 212 SUPERFAMILY SSF48150 3 208 2.83E-72 T 13-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 THL1_RS08070 7bb5bf3ad614e7ececa5dbbc3eaa6ecf 212 TIGRFAM TIGR01083 nth: endonuclease III 5 194 1.2E-85 T 13-09-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 THL1_RS08070 7bb5bf3ad614e7ececa5dbbc3eaa6ecf 212 Gene3D G3DSA:1.10.340.30 23 122 1.3E-34 T 13-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 THL1_RS08070 7bb5bf3ad614e7ececa5dbbc3eaa6ecf 212 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 168 1.1E-19 T 13-09-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 THL1_RS08070 7bb5bf3ad614e7ececa5dbbc3eaa6ecf 212 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 187 203 - T 13-09-2016 IPR004035 Endonuclease III, iron-sulphur binding site THL1_RS08070 7bb5bf3ad614e7ececa5dbbc3eaa6ecf 212 PANTHER PTHR10359 1 212 6.1E-90 T 13-09-2016 THL1_RS08070 7bb5bf3ad614e7ececa5dbbc3eaa6ecf 212 Hamap MF_00942 Endonuclease III [nth]. 1 209 37.596 T 13-09-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 THL1_RS08070 7bb5bf3ad614e7ececa5dbbc3eaa6ecf 212 SMART SM00525 186 206 7.2E-5 T 13-09-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: REACT_216 THL1_RS08070 7bb5bf3ad614e7ececa5dbbc3eaa6ecf 212 PIRSF PIRSF001435 1 212 5.1E-52 T 13-09-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 THL1_RS08070 7bb5bf3ad614e7ececa5dbbc3eaa6ecf 212 Pfam PF00633 Helix-hairpin-helix motif 100 127 2.2E-9 T 13-09-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 THL1_RS08070 7bb5bf3ad614e7ececa5dbbc3eaa6ecf 212 PANTHER PTHR10359:SF18 1 212 6.1E-90 T 13-09-2016 THL1_RS21485 03376860ff8dc99de9eb8eb755f04f81 595 PANTHER PTHR11935 54 150 3.8E-78 T 13-09-2016 THL1_RS21485 03376860ff8dc99de9eb8eb755f04f81 595 PANTHER PTHR11935:SF93 174 406 3.8E-78 T 13-09-2016 THL1_RS21485 03376860ff8dc99de9eb8eb755f04f81 595 Pfam PF14864 Alkyl sulfatase C-terminal 475 584 6.5E-16 T 13-09-2016 IPR029229 Alkyl sulfatase, C-terminal THL1_RS21485 03376860ff8dc99de9eb8eb755f04f81 595 SMART SM00849 63 280 3.1E-21 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS21485 03376860ff8dc99de9eb8eb755f04f81 595 Pfam PF00753 Metallo-beta-lactamase superfamily 61 278 8.0E-25 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS21485 03376860ff8dc99de9eb8eb755f04f81 595 Gene3D G3DSA:3.60.15.10 190 310 4.6E-46 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS21485 03376860ff8dc99de9eb8eb755f04f81 595 Gene3D G3DSA:3.60.15.10 48 148 4.6E-46 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS21485 03376860ff8dc99de9eb8eb755f04f81 595 SUPERFAMILY SSF55718 475 584 5.0E-19 T 13-09-2016 IPR003033 SCP2 sterol-binding domain THL1_RS21485 03376860ff8dc99de9eb8eb755f04f81 595 Pfam PF14863 Alkyl sulfatase dimerisation 317 454 2.4E-50 T 13-09-2016 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 THL1_RS21485 03376860ff8dc99de9eb8eb755f04f81 595 SUPERFAMILY SSF56281 11 456 7.47E-120 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS21485 03376860ff8dc99de9eb8eb755f04f81 595 PANTHER PTHR11935 174 406 3.8E-78 T 13-09-2016 THL1_RS21485 03376860ff8dc99de9eb8eb755f04f81 595 PANTHER PTHR11935:SF93 54 150 3.8E-78 T 13-09-2016 THL1_RS06780 b7f3a2ed67bfe6d897756bcfb4a383a6 84 Gene3D G3DSA:3.30.1070.10 33 83 6.2E-21 T 13-09-2016 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 THL1_RS06780 b7f3a2ed67bfe6d897756bcfb4a383a6 84 SUPERFAMILY SSF55229 33 83 2.48E-15 T 13-09-2016 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 THL1_RS06780 b7f3a2ed67bfe6d897756bcfb4a383a6 84 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 83 5.3E-34 T 13-09-2016 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 THL1_RS06780 b7f3a2ed67bfe6d897756bcfb4a383a6 84 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 84 19.645 T 13-09-2016 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 THL1_RS06780 b7f3a2ed67bfe6d897756bcfb4a383a6 84 PANTHER PTHR33404 1 83 6.2E-29 T 13-09-2016 THL1_RS06780 b7f3a2ed67bfe6d897756bcfb4a383a6 84 Pfam PF03776 Septum formation topological specificity factor MinE 15 82 5.0E-26 T 13-09-2016 IPR005527 Septum formation topological specificity factor MinE GO:0032955|GO:0051301 THL1_RS25375 f37c189f71017115f3fd8e6f9d2a848b 783 PANTHER PTHR32282 17 684 2.6E-191 T 13-09-2016 THL1_RS25375 f37c189f71017115f3fd8e6f9d2a848b 783 Gene3D G3DSA:3.40.710.10 270 625 7.6E-62 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS25375 f37c189f71017115f3fd8e6f9d2a848b 783 SUPERFAMILY SSF56601 211 642 1.91E-88 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS25375 f37c189f71017115f3fd8e6f9d2a848b 783 PANTHER PTHR32282:SF0 17 684 2.6E-191 T 13-09-2016 THL1_RS25375 f37c189f71017115f3fd8e6f9d2a848b 783 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 698 779 7.8E-18 T 13-09-2016 IPR009647 Penicillin-binding, C-terminal KEGG: 00230+2.4.2.-|KEGG: 00514+2.4.2.-|UniPathway: UPA00219 THL1_RS25375 f37c189f71017115f3fd8e6f9d2a848b 783 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 44 781 1.5E-240 T 13-09-2016 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 KEGG: 00230+2.4.2.-|KEGG: 00514+2.4.2.-|UniPathway: UPA00219 THL1_RS25375 f37c189f71017115f3fd8e6f9d2a848b 783 SUPERFAMILY SSF53955 44 261 5.62E-64 T 13-09-2016 IPR023346 Lysozyme-like domain THL1_RS25375 f37c189f71017115f3fd8e6f9d2a848b 783 Pfam PF00912 Transglycosylase 63 229 8.2E-50 T 13-09-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 THL1_RS25375 f37c189f71017115f3fd8e6f9d2a848b 783 Gene3D G3DSA:1.10.3810.10 61 245 1.6E-51 T 13-09-2016 THL1_RS25375 f37c189f71017115f3fd8e6f9d2a848b 783 Pfam PF00905 Penicillin binding protein transpeptidase domain 305 544 3.5E-10 T 13-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THL1_RS01625 ff6233b3cd0831c06899e621377be7b0 396 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 117 127 - T 13-09-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 THL1_RS01625 ff6233b3cd0831c06899e621377be7b0 396 SUPERFAMILY SSF55973 112 233 4.32E-50 T 13-09-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 THL1_RS01625 ff6233b3cd0831c06899e621377be7b0 396 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 234 368 6.0E-66 T 13-09-2016 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 THL1_RS01625 ff6233b3cd0831c06899e621377be7b0 396 Gene3D G3DSA:3.30.300.10 245 394 1.3E-68 T 13-09-2016 THL1_RS01625 ff6233b3cd0831c06899e621377be7b0 396 SUPERFAMILY SSF55973 234 393 3.77E-67 T 13-09-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 THL1_RS01625 ff6233b3cd0831c06899e621377be7b0 396 Gene3D G3DSA:3.30.300.10 135 234 4.1E-40 T 13-09-2016 THL1_RS01625 ff6233b3cd0831c06899e621377be7b0 396 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 394 56.262 T 13-09-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 THL1_RS01625 ff6233b3cd0831c06899e621377be7b0 396 Pfam PF02772 S-adenosylmethionine synthetase, central domain 115 232 2.1E-42 T 13-09-2016 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 THL1_RS01625 ff6233b3cd0831c06899e621377be7b0 396 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 260 268 - T 13-09-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 THL1_RS01625 ff6233b3cd0831c06899e621377be7b0 396 Gene3D G3DSA:3.30.300.10 12 134 6.8E-47 T 13-09-2016 THL1_RS01625 ff6233b3cd0831c06899e621377be7b0 396 PIRSF PIRSF000497 1 394 1.4E-168 T 13-09-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 THL1_RS01625 ff6233b3cd0831c06899e621377be7b0 396 PANTHER PTHR11964 6 389 5.1E-263 T 13-09-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 THL1_RS01625 ff6233b3cd0831c06899e621377be7b0 396 SUPERFAMILY SSF55973 6 111 1.41E-45 T 13-09-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 THL1_RS01625 ff6233b3cd0831c06899e621377be7b0 396 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 393 4.0E-182 T 13-09-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 THL1_RS01625 ff6233b3cd0831c06899e621377be7b0 396 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 102 6.8E-41 T 13-09-2016 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 THL1_RS03470 9748cd2c0522a4c770c0f96b3ab8b3d7 143 PANTHER PTHR11661 1 142 3.9E-70 T 13-09-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 THL1_RS03470 9748cd2c0522a4c770c0f96b3ab8b3d7 143 Gene3D G3DSA:3.30.1550.10 2 72 2.8E-37 T 13-09-2016 IPR020784 Ribosomal protein L11, N-terminal THL1_RS03470 9748cd2c0522a4c770c0f96b3ab8b3d7 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 29.973 T 13-09-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 THL1_RS03470 9748cd2c0522a4c770c0f96b3ab8b3d7 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 4.0E-23 T 13-09-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 THL1_RS03470 9748cd2c0522a4c770c0f96b3ab8b3d7 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 5.0E-65 T 13-09-2016 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 THL1_RS03470 9748cd2c0522a4c770c0f96b3ab8b3d7 143 SUPERFAMILY SSF54747 3 72 2.75E-29 T 13-09-2016 IPR020784 Ribosomal protein L11, N-terminal THL1_RS03470 9748cd2c0522a4c770c0f96b3ab8b3d7 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 7.8E-28 T 13-09-2016 IPR020784 Ribosomal protein L11, N-terminal THL1_RS03470 9748cd2c0522a4c770c0f96b3ab8b3d7 143 SMART SM00649 9 141 4.1E-82 T 13-09-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 THL1_RS03470 9748cd2c0522a4c770c0f96b3ab8b3d7 143 SUPERFAMILY SSF46906 68 141 9.81E-24 T 13-09-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 THL1_RS03470 9748cd2c0522a4c770c0f96b3ab8b3d7 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 72 4.0E-16 T 13-09-2016 THL1_RS03470 9748cd2c0522a4c770c0f96b3ab8b3d7 143 Gene3D G3DSA:1.10.10.250 73 141 1.2E-29 T 13-09-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 THL1_RS03470 9748cd2c0522a4c770c0f96b3ab8b3d7 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 13-09-2016 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 THL1_RS04555 175581d00ee1acf1e4d4878b8e6c0e55 335 SUPERFAMILY SSF52172 4 117 6.55E-29 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS04555 175581d00ee1acf1e4d4878b8e6c0e55 335 Pfam PF00072 Response regulator receiver domain 5 114 1.6E-21 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS04555 175581d00ee1acf1e4d4878b8e6c0e55 335 Gene3D G3DSA:3.40.1550.10 145 334 1.6E-33 T 13-09-2016 IPR028976 CheC-like domain THL1_RS04555 175581d00ee1acf1e4d4878b8e6c0e55 335 Gene3D G3DSA:3.40.50.2300 4 115 1.5E-26 T 13-09-2016 THL1_RS04555 175581d00ee1acf1e4d4878b8e6c0e55 335 SMART SM00448 2 114 8.3E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS04555 175581d00ee1acf1e4d4878b8e6c0e55 335 PANTHER PTHR26402 2 114 4.2E-27 T 13-09-2016 THL1_RS04555 175581d00ee1acf1e4d4878b8e6c0e55 335 SUPERFAMILY SSF103039 145 332 1.57E-39 T 13-09-2016 IPR028976 CheC-like domain THL1_RS24530 517f3d426741735147dd9f3291cf8c92 255 PANTHER PTHR11751 93 115 6.4E-44 T 13-09-2016 THL1_RS24530 517f3d426741735147dd9f3291cf8c92 255 PANTHER PTHR11751:SF355 93 115 6.4E-44 T 13-09-2016 THL1_RS24530 517f3d426741735147dd9f3291cf8c92 255 PANTHER PTHR11751 12 77 6.4E-44 T 13-09-2016 THL1_RS24530 517f3d426741735147dd9f3291cf8c92 255 SMART SM00345 15 74 5.9E-25 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS24530 517f3d426741735147dd9f3291cf8c92 255 Gene3D G3DSA:1.10.10.10 4 75 2.7E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS24530 517f3d426741735147dd9f3291cf8c92 255 PANTHER PTHR11751:SF355 12 77 6.4E-44 T 13-09-2016 THL1_RS24530 517f3d426741735147dd9f3291cf8c92 255 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.9E-22 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS24530 517f3d426741735147dd9f3291cf8c92 255 SMART SM00895 99 231 3.4E-22 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS24530 517f3d426741735147dd9f3291cf8c92 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 5.7E-11 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS24530 517f3d426741735147dd9f3291cf8c92 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 5.7E-11 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS24530 517f3d426741735147dd9f3291cf8c92 255 SUPERFAMILY SSF48008 96 237 3.66E-26 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS24530 517f3d426741735147dd9f3291cf8c92 255 Pfam PF07729 FCD domain 99 230 6.3E-25 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS24530 517f3d426741735147dd9f3291cf8c92 255 Gene3D G3DSA:1.20.120.530 96 238 1.4E-24 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS24530 517f3d426741735147dd9f3291cf8c92 255 SUPERFAMILY SSF46785 6 76 3.06E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00680 04c98fe83aaaa07edebf8474732c538d 174 PANTHER PTHR28026:SF3 1 173 7.2E-57 T 13-09-2016 THL1_RS00680 04c98fe83aaaa07edebf8474732c538d 174 Pfam PF06127 Protein of unknown function (DUF962) 1 145 1.0E-25 T 13-09-2016 IPR009305 Protein of unknown function DUF962 THL1_RS00680 04c98fe83aaaa07edebf8474732c538d 174 PANTHER PTHR28026 1 173 7.2E-57 T 13-09-2016 THL1_RS01790 3c3b56a2e49eefd91b507cc9bd71e3f8 652 SUPERFAMILY SSF46548 224 352 1.05E-19 T 13-09-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 THL1_RS01790 3c3b56a2e49eefd91b507cc9bd71e3f8 652 Gene3D G3DSA:1.10.1060.10 222 354 3.8E-26 T 13-09-2016 THL1_RS01790 3c3b56a2e49eefd91b507cc9bd71e3f8 652 PANTHER PTHR11921 217 634 3.1E-175 T 13-09-2016 THL1_RS01790 3c3b56a2e49eefd91b507cc9bd71e3f8 652 Pfam PF11982 Domain of unknown function (DUF3483) 4 220 2.8E-92 T 13-09-2016 IPR021872 Protein of unknown function DUF3483 THL1_RS01790 3c3b56a2e49eefd91b507cc9bd71e3f8 652 Pfam PF02754 Cysteine-rich domain 525 611 4.3E-13 T 13-09-2016 IPR004017 Cysteine-rich domain THL1_RS01790 3c3b56a2e49eefd91b507cc9bd71e3f8 652 Pfam PF02754 Cysteine-rich domain 402 481 1.1E-4 T 13-09-2016 IPR004017 Cysteine-rich domain THL1_RS01790 3c3b56a2e49eefd91b507cc9bd71e3f8 652 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 323 334 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS01790 3c3b56a2e49eefd91b507cc9bd71e3f8 652 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 245 256 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS01790 3c3b56a2e49eefd91b507cc9bd71e3f8 652 Pfam PF13183 4Fe-4S dicluster domain 242 336 6.2E-11 T 13-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THL1_RS01790 3c3b56a2e49eefd91b507cc9bd71e3f8 652 PANTHER PTHR11921:SF22 217 634 3.1E-175 T 13-09-2016 THL1_RS23320 578b9d59c387f29695c7fd5274b5e6e4 347 SUPERFAMILY SSF51735 2 131 1.7E-15 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23320 578b9d59c387f29695c7fd5274b5e6e4 347 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 2 114 1.5E-11 T 13-09-2016 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 THL1_RS23320 578b9d59c387f29695c7fd5274b5e6e4 347 PANTHER PTHR12286 1 192 2.4E-47 T 13-09-2016 THL1_RS23320 578b9d59c387f29695c7fd5274b5e6e4 347 Gene3D G3DSA:3.40.50.720 2 127 2.3E-17 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23320 578b9d59c387f29695c7fd5274b5e6e4 347 PANTHER PTHR12286:SF4 1 192 2.4E-47 T 13-09-2016 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 Gene3D G3DSA:3.30.70.1430 565 646 2.0E-5 T 13-09-2016 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 Pfam PF00873 AcrB/AcrD/AcrF family 17 1010 4.8E-157 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 PRINTS PR00702 Acriflavin resistance protein family signature 450 473 1.2E-22 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 PRINTS PR00702 Acriflavin resistance protein family signature 475 498 1.2E-22 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 PRINTS PR00702 Acriflavin resistance protein family signature 51 69 1.2E-22 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 PRINTS PR00702 Acriflavin resistance protein family signature 397 421 1.2E-22 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 PRINTS PR00702 Acriflavin resistance protein family signature 343 366 1.2E-22 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 PRINTS PR00702 Acriflavin resistance protein family signature 23 47 1.2E-22 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 Gene3D G3DSA:3.30.2090.10 195 276 1.7E-8 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 SUPERFAMILY SSF82866 797 1019 1.22E-42 T 13-09-2016 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 SUPERFAMILY SSF82866 303 502 1.96E-34 T 13-09-2016 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 Gene3D G3DSA:3.30.70.1430 53 152 1.0E-17 T 13-09-2016 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 SUPERFAMILY SSF82693 561 641 1.36E-7 T 13-09-2016 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 PANTHER PTHR32063:SF7 14 1009 0.0 T 13-09-2016 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 SUPERFAMILY SSF82693 53 148 8.72E-15 T 13-09-2016 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 Gene3D G3DSA:3.30.2090.10 713 799 5.3E-16 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 PANTHER PTHR32063 14 1009 0.0 T 13-09-2016 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 SUPERFAMILY SSF82714 714 800 4.84E-17 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 SUPERFAMILY SSF82714 197 276 1.83E-9 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 SUPERFAMILY SSF82693 150 195 1.92E-19 T 13-09-2016 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 SUPERFAMILY SSF82693 281 337 1.92E-19 T 13-09-2016 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 Gene3D G3DSA:1.10.3850.10 287 502 4.1E-42 T 13-09-2016 THL1_RS17135 5c0bc353552a4653f8f6dac44ebce1e0 1034 Gene3D G3DSA:1.10.3850.10 804 1017 8.3E-49 T 13-09-2016 THL1_RS09800 f1bb8b856838cc2f02e3df0dcb882182 933 Pfam PF03023 MviN-like protein 490 901 5.2E-13 T 13-09-2016 IPR004268 Peptidoglycan biosynthesis protein MurJ THL1_RS07130 3ebc1aab4ba3f42e1b551a8c982fd54a 400 ProSitePatterns PS00737 Thiolases signature 2. 346 362 - T 13-09-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 THL1_RS07130 3ebc1aab4ba3f42e1b551a8c982fd54a 400 SUPERFAMILY SSF53901 1 274 6.24E-67 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS07130 3ebc1aab4ba3f42e1b551a8c982fd54a 400 PANTHER PTHR18919 1 400 3.0E-201 T 13-09-2016 THL1_RS07130 3ebc1aab4ba3f42e1b551a8c982fd54a 400 Pfam PF00108 Thiolase, N-terminal domain 5 269 7.1E-58 T 13-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THL1_RS07130 3ebc1aab4ba3f42e1b551a8c982fd54a 400 Gene3D G3DSA:3.40.47.10 4 125 7.1E-56 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS07130 3ebc1aab4ba3f42e1b551a8c982fd54a 400 Gene3D G3DSA:3.40.47.10 186 282 7.1E-56 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS07130 3ebc1aab4ba3f42e1b551a8c982fd54a 400 SUPERFAMILY SSF53901 278 398 1.03E-39 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS07130 3ebc1aab4ba3f42e1b551a8c982fd54a 400 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 398 5.7E-123 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS07130 3ebc1aab4ba3f42e1b551a8c982fd54a 400 Pfam PF02803 Thiolase, C-terminal domain 278 398 4.0E-43 T 13-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THL1_RS07130 3ebc1aab4ba3f42e1b551a8c982fd54a 400 Gene3D G3DSA:3.40.47.10 141 185 7.2E-59 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS07130 3ebc1aab4ba3f42e1b551a8c982fd54a 400 Gene3D G3DSA:3.40.47.10 284 399 7.2E-59 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS07130 3ebc1aab4ba3f42e1b551a8c982fd54a 400 PANTHER PTHR18919:SF14 1 400 3.0E-201 T 13-09-2016 THL1_RS07130 3ebc1aab4ba3f42e1b551a8c982fd54a 400 PIRSF PIRSF000429 1 400 3.9E-112 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS05460 6251cbe0bdfa342874223053026dd899 683 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 52 682 8.5E-108 T 13-09-2016 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 THL1_RS05460 6251cbe0bdfa342874223053026dd899 683 PANTHER PTHR32552:SF29 42 683 3.3E-244 T 13-09-2016 THL1_RS05460 6251cbe0bdfa342874223053026dd899 683 Pfam PF07715 TonB-dependent Receptor Plug Domain 50 149 1.4E-16 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS05460 6251cbe0bdfa342874223053026dd899 683 PANTHER PTHR32552 42 683 3.3E-244 T 13-09-2016 THL1_RS05460 6251cbe0bdfa342874223053026dd899 683 Gene3D G3DSA:2.170.130.10 32 156 4.4E-35 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS05460 6251cbe0bdfa342874223053026dd899 683 PANTHER PTHR32552:SF29 15 20 3.3E-244 T 13-09-2016 THL1_RS05460 6251cbe0bdfa342874223053026dd899 683 Pfam PF00593 TonB dependent receptor 454 681 2.7E-30 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS05460 6251cbe0bdfa342874223053026dd899 683 Gene3D G3DSA:2.40.170.20 164 681 1.5E-148 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS05460 6251cbe0bdfa342874223053026dd899 683 PANTHER PTHR32552 15 20 3.3E-244 T 13-09-2016 THL1_RS05460 6251cbe0bdfa342874223053026dd899 683 SUPERFAMILY SSF56935 14 682 2.02E-135 T 13-09-2016 THL1_RS16160 107697ee52a7fa5638de85288cb98dfb 334 PANTHER PTHR35862 1 159 1.8E-81 T 13-09-2016 THL1_RS16160 107697ee52a7fa5638de85288cb98dfb 334 PANTHER PTHR35862:SF1 1 159 1.8E-81 T 13-09-2016 THL1_RS16160 107697ee52a7fa5638de85288cb98dfb 334 PANTHER PTHR35862 197 333 1.8E-81 T 13-09-2016 THL1_RS16160 107697ee52a7fa5638de85288cb98dfb 334 PANTHER PTHR35862:SF1 197 333 1.8E-81 T 13-09-2016 THL1_RS16160 107697ee52a7fa5638de85288cb98dfb 334 Pfam PF04865 Baseplate J-like protein 118 291 6.1E-23 T 13-09-2016 IPR006949 Baseplate protein J-like THL1_RS16160 107697ee52a7fa5638de85288cb98dfb 334 PIRSF PIRSF020481 1 333 9.6E-104 T 13-09-2016 IPR014507 Baseplate assembly protein J, predicted THL1_RS22635 e519dccf437a0fa435cd126ad5ea82c5 289 SUPERFAMILY SSF46934 4 54 2.14E-16 T 13-09-2016 IPR009060 UBA-like GO:0005515 THL1_RS22635 e519dccf437a0fa435cd126ad5ea82c5 289 Gene3D G3DSA:1.10.286.20 186 230 3.4E-13 T 13-09-2016 THL1_RS22635 e519dccf437a0fa435cd126ad5ea82c5 289 PANTHER PTHR11741 1 287 8.0E-122 T 13-09-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 THL1_RS22635 e519dccf437a0fa435cd126ad5ea82c5 289 SUPERFAMILY SSF54713 56 141 8.83E-15 T 13-09-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 THL1_RS22635 e519dccf437a0fa435cd126ad5ea82c5 289 Gene3D G3DSA:3.30.479.20 57 95 5.2E-29 T 13-09-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 THL1_RS22635 e519dccf437a0fa435cd126ad5ea82c5 289 Gene3D G3DSA:3.30.479.20 169 184 5.2E-29 T 13-09-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 THL1_RS22635 e519dccf437a0fa435cd126ad5ea82c5 289 Gene3D G3DSA:3.30.479.20 232 270 5.2E-29 T 13-09-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 THL1_RS22635 e519dccf437a0fa435cd126ad5ea82c5 289 Pfam PF00889 Elongation factor TS 73 267 9.6E-59 T 13-09-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 THL1_RS22635 e519dccf437a0fa435cd126ad5ea82c5 289 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 13-09-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 THL1_RS22635 e519dccf437a0fa435cd126ad5ea82c5 289 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 284 8.6E-97 T 13-09-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 THL1_RS22635 e519dccf437a0fa435cd126ad5ea82c5 289 SUPERFAMILY SSF54713 143 284 4.06E-49 T 13-09-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 THL1_RS22635 e519dccf437a0fa435cd126ad5ea82c5 289 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 13-09-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 THL1_RS22635 e519dccf437a0fa435cd126ad5ea82c5 289 Hamap MF_00050 Elongation factor Ts [tsf]. 1 284 72.563 T 13-09-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 THL1_RS22635 e519dccf437a0fa435cd126ad5ea82c5 289 Gene3D G3DSA:1.10.8.10 2 55 9.1E-25 T 13-09-2016 THL1_RS19430 f46bb217140f51473293782c369ab3f7 250 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 46 229 2.9E-84 T 13-09-2016 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19430 f46bb217140f51473293782c369ab3f7 250 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 46 63 3.8E-59 T 13-09-2016 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19430 f46bb217140f51473293782c369ab3f7 250 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 205 229 3.8E-59 T 13-09-2016 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19430 f46bb217140f51473293782c369ab3f7 250 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 63 83 3.8E-59 T 13-09-2016 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19430 f46bb217140f51473293782c369ab3f7 250 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 122 142 3.8E-59 T 13-09-2016 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19430 f46bb217140f51473293782c369ab3f7 250 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 101 121 3.8E-59 T 13-09-2016 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19430 f46bb217140f51473293782c369ab3f7 250 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 157 183 3.8E-59 T 13-09-2016 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19430 f46bb217140f51473293782c369ab3f7 250 Pfam PF01578 Cytochrome C assembly protein 25 185 2.4E-25 T 13-09-2016 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 THL1_RS19430 f46bb217140f51473293782c369ab3f7 250 PANTHER PTHR30071 3 225 4.5E-78 T 13-09-2016 THL1_RS05140 392fb6cd3ea516b2afa7a3a2eb3f8898 667 Gene3D G3DSA:3.90.1150.10 255 386 6.6E-34 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS05140 392fb6cd3ea516b2afa7a3a2eb3f8898 667 ProSitePatterns PS00211 ABC transporters family signature. 562 576 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS05140 392fb6cd3ea516b2afa7a3a2eb3f8898 667 Pfam PF00155 Aminotransferase class I and II 33 382 1.0E-67 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS05140 392fb6cd3ea516b2afa7a3a2eb3f8898 667 PANTHER PTHR24220:SF472 417 667 3.9E-139 T 13-09-2016 THL1_RS05140 392fb6cd3ea516b2afa7a3a2eb3f8898 667 Pfam PF00005 ABC transporter 431 590 7.1E-34 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS05140 392fb6cd3ea516b2afa7a3a2eb3f8898 667 SUPERFAMILY SSF52540 415 660 2.89E-73 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05140 392fb6cd3ea516b2afa7a3a2eb3f8898 667 Gene3D G3DSA:3.40.640.10 47 254 4.5E-72 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS05140 392fb6cd3ea516b2afa7a3a2eb3f8898 667 Gene3D G3DSA:3.40.50.300 414 662 9.0E-80 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05140 392fb6cd3ea516b2afa7a3a2eb3f8898 667 SUPERFAMILY SSF53383 23 386 8.91E-114 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS05140 392fb6cd3ea516b2afa7a3a2eb3f8898 667 PANTHER PTHR24220 417 667 3.9E-139 T 13-09-2016 THL1_RS05140 392fb6cd3ea516b2afa7a3a2eb3f8898 667 SMART SM00382 440 638 4.1E-16 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS27515 68711ded00c7dc6cf2e0c3864eb04eb5 234 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 84 194 1.3E-15 T 13-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THL1_RS27515 68711ded00c7dc6cf2e0c3864eb04eb5 234 Gene3D G3DSA:3.40.50.1000 2 225 1.1E-41 T 13-09-2016 IPR023214 HAD-like domain THL1_RS27515 68711ded00c7dc6cf2e0c3864eb04eb5 234 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 199 3.6E-23 T 13-09-2016 IPR023214 HAD-like domain THL1_RS27515 68711ded00c7dc6cf2e0c3864eb04eb5 234 PANTHER PTHR12725:SF65 1 229 2.5E-63 T 13-09-2016 THL1_RS27515 68711ded00c7dc6cf2e0c3864eb04eb5 234 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 101 199 1.3E-10 T 13-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THL1_RS27515 68711ded00c7dc6cf2e0c3864eb04eb5 234 SUPERFAMILY SSF56784 3 227 3.42E-47 T 13-09-2016 IPR023214 HAD-like domain THL1_RS27515 68711ded00c7dc6cf2e0c3864eb04eb5 234 PANTHER PTHR12725 1 229 2.5E-63 T 13-09-2016 THL1_RS27515 68711ded00c7dc6cf2e0c3864eb04eb5 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 9.3E-6 T 13-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THL1_RS27515 68711ded00c7dc6cf2e0c3864eb04eb5 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 159 9.3E-6 T 13-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THL1_RS27515 68711ded00c7dc6cf2e0c3864eb04eb5 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 189 202 9.3E-6 T 13-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THL1_RS22865 3fcca43f4379b5628b8adc80b70b3fe3 429 SMART SM01154 41 417 2.5E-179 T 13-09-2016 IPR012548 Protein of unknown function DUF1704 THL1_RS22865 3fcca43f4379b5628b8adc80b70b3fe3 429 TIGRFAM TIGR02421 QEGLA: conserved hypothetical protein 22 410 1.6E-127 T 13-09-2016 IPR012656 Conserved hypothetical protein CHP02421, QEGLA THL1_RS22865 3fcca43f4379b5628b8adc80b70b3fe3 429 Pfam PF08014 Domain of unknown function (DUF1704) 43 414 9.3E-130 T 13-09-2016 IPR012548 Protein of unknown function DUF1704 THL1_RS17310 450df998d885270643947f536595dc75 244 TIGRFAM TIGR02780 TrbJ_Ti: P-type conjugative transfer protein TrbJ 21 243 2.8E-57 T 13-09-2016 IPR014147 Type IV conjugative transfer protein TrbJ THL1_RS11610 2e17b10235c9eefb03511ae7282a1c7e 296 Pfam PF05673 Protein of unknown function (DUF815) 35 288 3.9E-103 T 13-09-2016 IPR008533 Domain of unknown function DUF815 THL1_RS11610 2e17b10235c9eefb03511ae7282a1c7e 296 Gene3D G3DSA:3.40.50.300 59 221 5.7E-15 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11610 2e17b10235c9eefb03511ae7282a1c7e 296 PANTHER PTHR13779 7 189 7.0E-92 T 13-09-2016 THL1_RS11610 2e17b10235c9eefb03511ae7282a1c7e 296 SUPERFAMILY SSF52540 57 190 1.08E-23 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11610 2e17b10235c9eefb03511ae7282a1c7e 296 PANTHER PTHR13779:SF28 216 288 7.0E-92 T 13-09-2016 THL1_RS11610 2e17b10235c9eefb03511ae7282a1c7e 296 PANTHER PTHR13779:SF28 7 189 7.0E-92 T 13-09-2016 THL1_RS11610 2e17b10235c9eefb03511ae7282a1c7e 296 PANTHER PTHR13779 216 288 7.0E-92 T 13-09-2016 THL1_RS01630 7b40bf809b4ecd56cef379e5683551a4 333 Pfam PF12840 Helix-turn-helix domain 20 75 3.8E-10 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS01630 7b40bf809b4ecd56cef379e5683551a4 333 Pfam PF13489 Methyltransferase domain 153 300 1.8E-17 T 13-09-2016 THL1_RS01630 7b40bf809b4ecd56cef379e5683551a4 333 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 8.5E-10 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS01630 7b40bf809b4ecd56cef379e5683551a4 333 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 20 35 8.5E-10 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS01630 7b40bf809b4ecd56cef379e5683551a4 333 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 8.5E-10 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS01630 7b40bf809b4ecd56cef379e5683551a4 333 SMART SM00418 18 99 1.5E-8 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS01630 7b40bf809b4ecd56cef379e5683551a4 333 SUPERFAMILY SSF46785 11 205 2.22E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS01630 7b40bf809b4ecd56cef379e5683551a4 333 SUPERFAMILY SSF53335 157 313 2.41E-33 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS01630 7b40bf809b4ecd56cef379e5683551a4 333 PANTHER PTHR10108:SF820 39 302 2.9E-39 T 13-09-2016 THL1_RS01630 7b40bf809b4ecd56cef379e5683551a4 333 Gene3D G3DSA:3.40.50.150 127 302 3.4E-29 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS01630 7b40bf809b4ecd56cef379e5683551a4 333 PANTHER PTHR10108 39 302 2.9E-39 T 13-09-2016 THL1_RS01630 7b40bf809b4ecd56cef379e5683551a4 333 Gene3D G3DSA:1.10.10.10 6 90 6.5E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00320 d33d3a3b60cdb56161cdbd2b8a8b0904 542 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 257 271 - T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS00320 d33d3a3b60cdb56161cdbd2b8a8b0904 542 SUPERFAMILY SSF54373 293 476 9.81E-58 T 13-09-2016 THL1_RS00320 d33d3a3b60cdb56161cdbd2b8a8b0904 542 SUPERFAMILY SSF51905 475 535 2.91E-88 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS00320 d33d3a3b60cdb56161cdbd2b8a8b0904 542 SUPERFAMILY SSF51905 5 291 2.91E-88 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS00320 d33d3a3b60cdb56161cdbd2b8a8b0904 542 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 85 108 - T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS00320 d33d3a3b60cdb56161cdbd2b8a8b0904 542 PANTHER PTHR11552:SF51 4 533 5.0E-214 T 13-09-2016 THL1_RS00320 d33d3a3b60cdb56161cdbd2b8a8b0904 542 PANTHER PTHR11552 4 533 5.0E-214 T 13-09-2016 THL1_RS00320 d33d3a3b60cdb56161cdbd2b8a8b0904 542 Pfam PF05199 GMC oxidoreductase 390 526 3.6E-38 T 13-09-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 THL1_RS00320 d33d3a3b60cdb56161cdbd2b8a8b0904 542 Pfam PF00732 GMC oxidoreductase 8 298 8.9E-75 T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS00320 d33d3a3b60cdb56161cdbd2b8a8b0904 542 PIRSF PIRSF000137 3 541 1.2E-141 T 13-09-2016 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|UniPathway: UPA00529 THL1_RS00320 d33d3a3b60cdb56161cdbd2b8a8b0904 542 Gene3D G3DSA:3.50.50.60 4 129 1.9E-117 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS00320 d33d3a3b60cdb56161cdbd2b8a8b0904 542 Gene3D G3DSA:3.50.50.60 469 534 1.9E-117 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS00320 d33d3a3b60cdb56161cdbd2b8a8b0904 542 Gene3D G3DSA:3.50.50.60 190 316 1.9E-117 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10155 7dca8968787a47eac892e539542045ec 143 PRINTS PR00813 Bacterial general secretion pathway protein G signature 9 34 7.3E-20 T 13-09-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THL1_RS10155 7dca8968787a47eac892e539542045ec 143 PRINTS PR00813 Bacterial general secretion pathway protein G signature 45 63 7.3E-20 T 13-09-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THL1_RS10155 7dca8968787a47eac892e539542045ec 143 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 30 7.8E-9 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS10155 7dca8968787a47eac892e539542045ec 143 SUPERFAMILY SSF54523 35 142 8.89E-39 T 13-09-2016 THL1_RS10155 7dca8968787a47eac892e539542045ec 143 Pfam PF08334 Type II secretion system (T2SS), protein G 32 141 4.5E-43 T 13-09-2016 IPR013545 Type II secretion system protein G THL1_RS10155 7dca8968787a47eac892e539542045ec 143 Pfam PF13633 Prokaryotic N-terminal methylation site 7 31 1.3E-9 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS10155 7dca8968787a47eac892e539542045ec 143 Gene3D G3DSA:3.30.700.10 10 75 2.5E-10 T 13-09-2016 THL1_RS10155 7dca8968787a47eac892e539542045ec 143 PANTHER PTHR30093 4 143 1.0E-71 T 13-09-2016 THL1_RS10155 7dca8968787a47eac892e539542045ec 143 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 8 142 1.6E-62 T 13-09-2016 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 THL1_RS10155 7dca8968787a47eac892e539542045ec 143 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS10155 7dca8968787a47eac892e539542045ec 143 PANTHER PTHR30093:SF9 4 143 1.0E-71 T 13-09-2016 THL1_RS00990 62b1558142955cf20f6c9f767b17a83f 380 SUPERFAMILY SSF52540 22 263 1.28E-85 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00990 62b1558142955cf20f6c9f767b17a83f 380 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS00990 62b1558142955cf20f6c9f767b17a83f 380 PANTHER PTHR24220:SF481 24 327 2.4E-189 T 13-09-2016 THL1_RS00990 62b1558142955cf20f6c9f767b17a83f 380 SUPERFAMILY SSF50331 255 378 4.19E-15 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS00990 62b1558142955cf20f6c9f767b17a83f 380 Pfam PF00005 ABC transporter 39 180 2.5E-37 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS00990 62b1558142955cf20f6c9f767b17a83f 380 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 53 378 9.3E-128 T 13-09-2016 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 THL1_RS00990 62b1558142955cf20f6c9f767b17a83f 380 Gene3D G3DSA:3.40.50.300 15 256 1.2E-80 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00990 62b1558142955cf20f6c9f767b17a83f 380 PANTHER PTHR24220 24 327 2.4E-189 T 13-09-2016 THL1_RS00990 62b1558142955cf20f6c9f767b17a83f 380 Pfam PF08402 TOBE domain 300 378 8.2E-16 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS00990 62b1558142955cf20f6c9f767b17a83f 380 SMART SM00382 47 230 4.7E-17 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS21880 6d7186b2bec77bf385c120d2e14a73ab 314 SUPERFAMILY SSF53850 24 300 1.14E-77 T 13-09-2016 THL1_RS21880 6d7186b2bec77bf385c120d2e14a73ab 314 Gene3D G3DSA:3.40.190.100 117 235 8.0E-17 T 13-09-2016 THL1_RS21880 6d7186b2bec77bf385c120d2e14a73ab 314 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 31 284 1.9E-47 T 13-09-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 THL1_RS21880 6d7186b2bec77bf385c120d2e14a73ab 314 PANTHER PTHR30177 7 288 2.0E-115 T 13-09-2016 THL1_RS21880 6d7186b2bec77bf385c120d2e14a73ab 314 Gene3D G3DSA:3.40.190.10 236 300 2.5E-38 T 13-09-2016 THL1_RS21880 6d7186b2bec77bf385c120d2e14a73ab 314 Gene3D G3DSA:3.40.190.10 24 112 2.5E-38 T 13-09-2016 THL1_RS21880 6d7186b2bec77bf385c120d2e14a73ab 314 TIGRFAM TIGR03414 ABC_choline_bnd: choline ABC transporter, periplasmic binding protein 23 311 6.6E-137 T 13-09-2016 IPR017783 ABC transporter, choline, substrate-binding protein GO:0015871|GO:0033265|GO:0042597 THL1_RS21880 6d7186b2bec77bf385c120d2e14a73ab 314 PANTHER PTHR30177:SF6 7 288 2.0E-115 T 13-09-2016 THL1_RS05670 2eb365b3387135235d47345ac7614a41 303 Gene3D G3DSA:3.30.1700.10 128 282 1.0E-59 T 13-09-2016 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 THL1_RS05670 2eb365b3387135235d47345ac7614a41 303 Gene3D G3DSA:3.30.230.20 3 125 3.0E-47 T 13-09-2016 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 THL1_RS05670 2eb365b3387135235d47345ac7614a41 303 SUPERFAMILY SSF54211 3 125 3.64E-43 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS05670 2eb365b3387135235d47345ac7614a41 303 SUPERFAMILY SSF54211 134 277 2.5E-52 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS05670 2eb365b3387135235d47345ac7614a41 303 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 275 4.9E-109 T 13-09-2016 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 THL1_RS05670 2eb365b3387135235d47345ac7614a41 303 PANTHER PTHR33694 1 303 9.9E-136 T 13-09-2016 THL1_RS05670 2eb365b3387135235d47345ac7614a41 303 PANTHER PTHR33694:SF1 1 303 9.9E-136 T 13-09-2016 THL1_RS05670 2eb365b3387135235d47345ac7614a41 303 Hamap MF_00388 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [lpxC]. 2 280 49.963 T 13-09-2016 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 THL1_RS05670 2eb365b3387135235d47345ac7614a41 303 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 297 3.3E-120 T 13-09-2016 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108|KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00359 THL1_RS20115 a97e872f16f437305b156cac53443a07 434 SUPERFAMILY SSF56529 129 432 1.15E-95 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS20115 a97e872f16f437305b156cac53443a07 434 PANTHER PTHR11820:SF1 126 280 4.9E-167 T 13-09-2016 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 THL1_RS20115 a97e872f16f437305b156cac53443a07 434 PANTHER PTHR11820 4 95 4.9E-167 T 13-09-2016 THL1_RS20115 a97e872f16f437305b156cac53443a07 434 PANTHER PTHR11820 301 434 4.9E-167 T 13-09-2016 THL1_RS20115 a97e872f16f437305b156cac53443a07 434 Gene3D G3DSA:2.30.30.230 9 128 6.2E-31 T 13-09-2016 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 THL1_RS20115 a97e872f16f437305b156cac53443a07 434 PANTHER PTHR11820 126 280 4.9E-167 T 13-09-2016 THL1_RS20115 a97e872f16f437305b156cac53443a07 434 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 9 433 9.7E-185 T 13-09-2016 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 THL1_RS20115 a97e872f16f437305b156cac53443a07 434 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 132 428 6.6E-57 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS20115 a97e872f16f437305b156cac53443a07 434 SUPERFAMILY SSF63433 8 126 1.7E-28 T 13-09-2016 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 THL1_RS20115 a97e872f16f437305b156cac53443a07 434 PANTHER PTHR11820:SF1 4 95 4.9E-167 T 13-09-2016 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 THL1_RS20115 a97e872f16f437305b156cac53443a07 434 PANTHER PTHR11820:SF1 301 434 4.9E-167 T 13-09-2016 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 THL1_RS20115 a97e872f16f437305b156cac53443a07 434 Pfam PF09298 Fumarylacetoacetase N-terminal 23 126 8.3E-22 T 13-09-2016 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|UniPathway: UPA00139 THL1_RS20115 a97e872f16f437305b156cac53443a07 434 Gene3D G3DSA:3.90.850.10 129 427 1.7E-107 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS27985 7a6e4d2a0c04b8a39b3514abd4ccf8e8 128 Pfam PF03640 Secreted repeat of unknown function 32 69 5.6E-15 T 13-09-2016 IPR005297 Lipoprotein repeat THL1_RS27985 7a6e4d2a0c04b8a39b3514abd4ccf8e8 128 Pfam PF03640 Secreted repeat of unknown function 81 124 1.4E-20 T 13-09-2016 IPR005297 Lipoprotein repeat THL1_RS27985 7a6e4d2a0c04b8a39b3514abd4ccf8e8 128 PANTHER PTHR39335 11 126 6.1E-47 T 13-09-2016 THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 Gene3D G3DSA:3.30.450.40 178 351 9.8E-11 T 13-09-2016 IPR029016 GAF domain-like THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 SUPERFAMILY SSF52172 5 150 7.4E-38 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 PANTHER PTHR33121 738 1063 2.3E-79 T 13-09-2016 THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 SMART SM00086 439 481 0.71 T 13-09-2016 IPR001610 PAC motif THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 SMART SM00086 567 606 1.3E-5 T 13-09-2016 IPR001610 PAC motif THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 PANTHER PTHR33121:SF13 738 1063 2.3E-79 T 13-09-2016 THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 SMART SM00448 5 118 2.2E-35 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 SMART SM00448 1056 1168 7.3E-20 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 Pfam PF13185 GAF domain 201 337 3.1E-8 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 SUPERFAMILY SSF55781 204 349 1.57E-12 T 13-09-2016 IPR029016 GAF domain-like THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 SUPERFAMILY SSF55785 496 605 5.41E-27 T 13-09-2016 IPR000014 PAS domain THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 Pfam PF00990 Diguanylate cyclase, GGDEF domain 617 774 3.0E-50 T 13-09-2016 IPR000160 GGDEF domain THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 Gene3D G3DSA:3.20.20.450 792 1040 1.3E-91 T 13-09-2016 IPR001633 EAL domain THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 SUPERFAMILY SSF52172 1058 1188 4.98E-29 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 SUPERFAMILY SSF55073 622 778 2.28E-52 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 Gene3D G3DSA:3.40.50.2300 5 124 6.8E-37 T 13-09-2016 THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 Gene3D G3DSA:3.30.450.20 354 479 2.2E-13 T 13-09-2016 THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 PANTHER PTHR33121 617 623 2.3E-79 T 13-09-2016 THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 Gene3D G3DSA:3.40.50.2300 1058 1189 4.7E-28 T 13-09-2016 THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 PANTHER PTHR33121:SF13 617 623 2.3E-79 T 13-09-2016 THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 SUPERFAMILY SSF55785 352 479 1.54E-12 T 13-09-2016 IPR000014 PAS domain THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 SMART SM00091 489 558 4.1E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 SMART SM00091 362 429 3.1 T 13-09-2016 IPR000014 PAS domain THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 SMART SM00267 606 778 9.9E-70 T 13-09-2016 IPR000160 GGDEF domain THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 613 776 1.4E-48 T 13-09-2016 IPR000160 GGDEF domain THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 Pfam PF08448 PAS fold 368 483 6.8E-7 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 Pfam PF13426 PAS domain 501 605 3.5E-21 T 13-09-2016 IPR000014 PAS domain THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 Pfam PF00563 EAL domain 794 1028 4.5E-69 T 13-09-2016 IPR001633 EAL domain THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 SMART SM00052 788 1033 1.4E-105 T 13-09-2016 IPR001633 EAL domain THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 Pfam PF00072 Response regulator receiver domain 7 118 1.5E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 Pfam PF00072 Response regulator receiver domain 1059 1167 1.0E-18 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 Gene3D G3DSA:3.30.70.270 618 787 3.2E-60 T 13-09-2016 THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 Gene3D G3DSA:3.30.450.20 500 605 2.8E-35 T 13-09-2016 THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 493 613 2.0E-24 T 13-09-2016 IPR000014 PAS domain THL1_RS02980 9ad428eaeb8e99578c37c898b72ec028 1193 SUPERFAMILY SSF141868 797 1042 5.75E-86 T 13-09-2016 IPR001633 EAL domain THL1_RS22885 fbd486acb7de1a1ddd7f69ec79ececa2 300 Gene3D G3DSA:1.20.58.410 1 51 5.7E-9 T 13-09-2016 THL1_RS22885 fbd486acb7de1a1ddd7f69ec79ececa2 300 Gene3D G3DSA:3.30.160.20 163 240 3.3E-38 T 13-09-2016 IPR014720 Double-stranded RNA-binding domain THL1_RS22885 fbd486acb7de1a1ddd7f69ec79ececa2 300 SUPERFAMILY SSF75620 2 297 6.54E-122 T 13-09-2016 THL1_RS22885 fbd486acb7de1a1ddd7f69ec79ececa2 300 PANTHER PTHR11075:SF6 1 298 4.1E-144 T 13-09-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 THL1_RS22885 fbd486acb7de1a1ddd7f69ec79ececa2 300 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 180 196 - T 13-09-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THL1_RS22885 fbd486acb7de1a1ddd7f69ec79ececa2 300 Pfam PF00472 RF-1 domain 164 272 3.0E-40 T 13-09-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THL1_RS22885 fbd486acb7de1a1ddd7f69ec79ececa2 300 SMART SM00937 20 130 3.2E-52 T 13-09-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 THL1_RS22885 fbd486acb7de1a1ddd7f69ec79ececa2 300 PANTHER PTHR11075 1 298 4.1E-144 T 13-09-2016 THL1_RS22885 fbd486acb7de1a1ddd7f69ec79ececa2 300 Pfam PF03462 PCRF domain 2 155 1.4E-45 T 13-09-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 THL1_RS22885 fbd486acb7de1a1ddd7f69ec79ececa2 300 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 2 298 3.3E-142 T 13-09-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 THL1_RS26410 7524085416e638ee8c19653563718bcb 143 PANTHER PTHR38664 26 141 4.1E-21 T 13-09-2016 THL1_RS26410 7524085416e638ee8c19653563718bcb 143 TIGRFAM TIGR01837 PHA_granule_1: poly(hydroxyalkanoate) granule-associated protein 23 141 4.6E-41 T 13-09-2016 IPR008769 Poly granule associated THL1_RS26410 7524085416e638ee8c19653563718bcb 143 Pfam PF05597 Poly(hydroxyalcanoate) granule associated protein (phasin) 15 140 5.5E-44 T 13-09-2016 IPR008769 Poly granule associated THL1_RS26410 7524085416e638ee8c19653563718bcb 143 PANTHER PTHR38664:SF1 26 141 4.1E-21 T 13-09-2016 THL1_RS10800 aef15454af97903094b8bf6370059d2f 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 80 95 1.1E-24 T 13-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THL1_RS10800 aef15454af97903094b8bf6370059d2f 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 46 62 1.1E-24 T 13-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THL1_RS10800 aef15454af97903094b8bf6370059d2f 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 3 20 1.1E-24 T 13-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THL1_RS10800 aef15454af97903094b8bf6370059d2f 154 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 121 136 1.1E-24 T 13-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THL1_RS10800 aef15454af97903094b8bf6370059d2f 154 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 146 5.3E-43 T 13-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily THL1_RS10800 aef15454af97903094b8bf6370059d2f 154 SMART SM00226 1 149 2.8E-55 T 13-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily THL1_RS10800 aef15454af97903094b8bf6370059d2f 154 PANTHER PTHR11717 1 151 9.5E-62 T 13-09-2016 THL1_RS10800 aef15454af97903094b8bf6370059d2f 154 Gene3D G3DSA:3.40.50.270 1 150 6.1E-55 T 13-09-2016 THL1_RS10800 aef15454af97903094b8bf6370059d2f 154 PANTHER PTHR11717:SF7 1 151 9.5E-62 T 13-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THL1_RS10800 aef15454af97903094b8bf6370059d2f 154 SUPERFAMILY SSF52788 1 147 1.44E-51 T 13-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily THL1_RS09270 6cb643ba2de02b5d87d06d5fa15b9390 241 Pfam PF00753 Metallo-beta-lactamase superfamily 30 220 1.1E-19 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS09270 6cb643ba2de02b5d87d06d5fa15b9390 241 PANTHER PTHR11935:SF106 1 237 3.5E-74 T 13-09-2016 THL1_RS09270 6cb643ba2de02b5d87d06d5fa15b9390 241 SMART SM00849 32 220 6.0E-30 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS09270 6cb643ba2de02b5d87d06d5fa15b9390 241 PANTHER PTHR11935 1 237 3.5E-74 T 13-09-2016 THL1_RS09270 6cb643ba2de02b5d87d06d5fa15b9390 241 Gene3D G3DSA:3.60.15.10 8 233 2.1E-35 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS09270 6cb643ba2de02b5d87d06d5fa15b9390 241 SUPERFAMILY SSF56281 13 236 6.58E-41 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS07620 b14ee8d70985c564eada08295858602c 289 Pfam PF01418 Helix-turn-helix domain, rpiR family 6 80 6.1E-30 T 13-09-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 THL1_RS07620 b14ee8d70985c564eada08295858602c 289 PANTHER PTHR30514:SF7 1 275 1.2E-163 T 13-09-2016 THL1_RS07620 b14ee8d70985c564eada08295858602c 289 SUPERFAMILY SSF53697 96 281 1.2E-39 T 13-09-2016 THL1_RS07620 b14ee8d70985c564eada08295858602c 289 SUPERFAMILY SSF46689 5 81 1.06E-21 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS07620 b14ee8d70985c564eada08295858602c 289 Gene3D G3DSA:1.10.10.10 4 82 3.2E-30 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07620 b14ee8d70985c564eada08295858602c 289 Gene3D G3DSA:3.40.50.10490 99 267 1.5E-36 T 13-09-2016 THL1_RS07620 b14ee8d70985c564eada08295858602c 289 PANTHER PTHR30514 1 275 1.2E-163 T 13-09-2016 THL1_RS07620 b14ee8d70985c564eada08295858602c 289 Pfam PF01380 SIS domain 129 256 3.7E-20 T 13-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 THL1_RS23920 f3f42aa966ad087e36bf2ffa0699461a 476 PANTHER PTHR11455:SF18 1 474 9.3E-200 T 13-09-2016 THL1_RS23920 f3f42aa966ad087e36bf2ffa0699461a 476 PANTHER PTHR11455 1 474 9.3E-200 T 13-09-2016 THL1_RS23920 f3f42aa966ad087e36bf2ffa0699461a 476 SUPERFAMILY SSF48173 195 470 1.57E-105 T 13-09-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain THL1_RS23920 f3f42aa966ad087e36bf2ffa0699461a 476 PRINTS PR00147 DNA photolyase signature 346 364 5.4E-23 T 13-09-2016 IPR002081 Cryptochrome/DNA photolyase class 1 THL1_RS23920 f3f42aa966ad087e36bf2ffa0699461a 476 PRINTS PR00147 DNA photolyase signature 385 399 5.4E-23 T 13-09-2016 IPR002081 Cryptochrome/DNA photolyase class 1 THL1_RS23920 f3f42aa966ad087e36bf2ffa0699461a 476 PRINTS PR00147 DNA photolyase signature 326 342 5.4E-23 T 13-09-2016 IPR002081 Cryptochrome/DNA photolyase class 1 THL1_RS23920 f3f42aa966ad087e36bf2ffa0699461a 476 Gene3D G3DSA:3.40.50.620 2 146 2.1E-43 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS23920 f3f42aa966ad087e36bf2ffa0699461a 476 Pfam PF00875 DNA photolyase 4 166 1.8E-41 T 13-09-2016 IPR006050 DNA photolyase, N-terminal THL1_RS23920 f3f42aa966ad087e36bf2ffa0699461a 476 Gene3D G3DSA:1.10.579.10 287 471 4.8E-76 T 13-09-2016 THL1_RS23920 f3f42aa966ad087e36bf2ffa0699461a 476 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 326 338 - T 13-09-2016 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal THL1_RS23920 f3f42aa966ad087e36bf2ffa0699461a 476 SUPERFAMILY SSF52425 3 188 1.26E-50 T 13-09-2016 IPR006050 DNA photolyase, N-terminal THL1_RS23920 f3f42aa966ad087e36bf2ffa0699461a 476 Gene3D G3DSA:1.25.40.80 147 286 1.1E-41 T 13-09-2016 THL1_RS23920 f3f42aa966ad087e36bf2ffa0699461a 476 Pfam PF03441 FAD binding domain of DNA photolyase 276 469 4.1E-82 T 13-09-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain THL1_RS02055 ac7e27f8da26385c56374bcc64b3f8b8 346 SMART SM01236 185 288 4.7E-22 T 13-09-2016 THL1_RS02055 ac7e27f8da26385c56374bcc64b3f8b8 346 Gene3D G3DSA:1.20.910.10 118 339 2.6E-60 T 13-09-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 THL1_RS02055 ac7e27f8da26385c56374bcc64b3f8b8 346 Pfam PF14518 Iron-containing redox enzyme 154 325 2.0E-31 T 13-09-2016 IPR028201 PqqC-like protein THL1_RS02055 ac7e27f8da26385c56374bcc64b3f8b8 346 SUPERFAMILY SSF48613 120 334 1.08E-17 T 13-09-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 THL1_RS12090 26be25771aec257ddea082f197468655 376 Pfam PF00246 Zinc carboxypeptidase 131 233 7.4E-21 T 13-09-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 THL1_RS12090 26be25771aec257ddea082f197468655 376 SUPERFAMILY SSF53187 105 374 1.22E-52 T 13-09-2016 THL1_RS12090 26be25771aec257ddea082f197468655 376 PANTHER PTHR12756:SF18 1 301 4.7E-135 T 13-09-2016 THL1_RS12090 26be25771aec257ddea082f197468655 376 PANTHER PTHR12756 1 301 4.7E-135 T 13-09-2016 THL1_RS12090 26be25771aec257ddea082f197468655 376 Gene3D G3DSA:3.40.630.10 101 345 1.0E-37 T 13-09-2016 THL1_RS12090 26be25771aec257ddea082f197468655 376 SMART SM00631 110 363 0.0055 T 13-09-2016 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 THL1_RS08140 a37f2a8ff2c2c72ce03e8a2620283ff1 191 PANTHER PTHR34980:SF2 1 189 1.0E-47 T 13-09-2016 THL1_RS08140 a37f2a8ff2c2c72ce03e8a2620283ff1 191 PANTHER PTHR34980 1 189 1.0E-47 T 13-09-2016 THL1_RS27955 c85d5c452c99f35f33eee1759babba0f 90 PANTHER PTHR33175 1 90 1.1E-39 T 13-09-2016 THL1_RS27955 c85d5c452c99f35f33eee1759babba0f 90 SUPERFAMILY SSF47729 1 90 2.65E-31 T 13-09-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THL1_RS27955 c85d5c452c99f35f33eee1759babba0f 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.9E-16 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS27955 c85d5c452c99f35f33eee1759babba0f 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.9E-16 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS27955 c85d5c452c99f35f33eee1759babba0f 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.9E-16 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS27955 c85d5c452c99f35f33eee1759babba0f 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 13-09-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 THL1_RS27955 c85d5c452c99f35f33eee1759babba0f 90 SMART SM00411 1 90 1.5E-38 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS27955 c85d5c452c99f35f33eee1759babba0f 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 4.1E-33 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS27955 c85d5c452c99f35f33eee1759babba0f 90 Gene3D G3DSA:4.10.520.10 1 90 3.8E-35 T 13-09-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THL1_RS28010 cab7ce6eb992c41b0d4ef1939f7fdb80 298 SUPERFAMILY SSF51261 154 271 9.94E-30 T 13-09-2016 IPR011055 Duplicated hybrid motif THL1_RS28010 cab7ce6eb992c41b0d4ef1939f7fdb80 298 Gene3D G3DSA:2.70.70.10 148 271 2.0E-30 T 13-09-2016 THL1_RS28010 cab7ce6eb992c41b0d4ef1939f7fdb80 298 Pfam PF01551 Peptidase family M23 177 271 1.7E-23 T 13-09-2016 IPR016047 Peptidase M23 THL1_RS28010 cab7ce6eb992c41b0d4ef1939f7fdb80 298 Pfam PF13511 Domain of unknown function (DUF4124) 10 44 9.1E-10 T 13-09-2016 IPR025392 Domain of unknown function DUF4124 THL1_RS28010 cab7ce6eb992c41b0d4ef1939f7fdb80 298 PANTHER PTHR21666:SF204 48 295 1.2E-59 T 13-09-2016 THL1_RS28010 cab7ce6eb992c41b0d4ef1939f7fdb80 298 PANTHER PTHR21666 48 295 1.2E-59 T 13-09-2016 THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 SUPERFAMILY SSF158472 190 238 3.14E-6 T 13-09-2016 THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 470 3.4E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 431 3.4E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 445 3.4E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 489 3.4E-16 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 Pfam PF00672 HAMP domain 171 236 1.4E-11 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 SUPERFAMILY SSF55874 317 490 9.56E-47 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 Pfam PF00072 Response regulator receiver domain 515 624 5.7E-26 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 Gene3D G3DSA:1.10.287.130 256 315 2.5E-16 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 SUPERFAMILY SSF47384 249 328 1.0E-21 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 376 490 1.6E-27 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 SMART SM00388 263 328 1.6E-24 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 SMART SM00448 513 626 3.3E-38 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 Gene3D G3DSA:3.30.565.10 316 490 7.3E-46 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 Pfam PF09984 Uncharacterised signal transduction histidine kinase domain (DUF2222) 35 158 2.6E-8 T 13-09-2016 IPR019247 Histidine kinase BarA, N-terminal THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 PANTHER PTHR24423 183 221 2.9E-153 T 13-09-2016 THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 PANTHER PTHR24423 1 10 2.9E-153 T 13-09-2016 THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 PANTHER PTHR24423 242 630 2.9E-153 T 13-09-2016 THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 SUPERFAMILY SSF52172 511 631 4.7E-39 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 SMART SM00387 376 492 3.0E-39 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 Pfam PF00512 His Kinase A (phospho-acceptor) domain 263 328 1.7E-19 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 Gene3D G3DSA:3.40.50.2300 504 632 1.4E-43 T 13-09-2016 THL1_RS10990 4633f80d6d3bb5be4038e55968a107fd 635 SMART SM00304 189 241 3.0E-5 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS11195 a0bbed6497a2fdbd33d3a69b56d61fec 307 PANTHER PTHR10366 2 307 3.0E-73 T 13-09-2016 THL1_RS11195 a0bbed6497a2fdbd33d3a69b56d61fec 307 Gene3D G3DSA:3.40.50.720 1 174 2.9E-47 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11195 a0bbed6497a2fdbd33d3a69b56d61fec 307 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 234 2.0E-44 T 13-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 THL1_RS11195 a0bbed6497a2fdbd33d3a69b56d61fec 307 Gene3D G3DSA:3.90.25.10 175 306 1.6E-17 T 13-09-2016 THL1_RS11195 a0bbed6497a2fdbd33d3a69b56d61fec 307 SUPERFAMILY SSF51735 1 306 4.83E-76 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS22735 26a254159a37395a916287b06949dc1f 832 SUPERFAMILY SSF69593 262 521 9.81E-34 T 13-09-2016 THL1_RS22735 26a254159a37395a916287b06949dc1f 832 PANTHER PTHR12563 1 130 0.0 T 13-09-2016 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00557 THL1_RS22735 26a254159a37395a916287b06949dc1f 832 PANTHER PTHR12563 149 823 0.0 T 13-09-2016 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00557 THL1_RS22735 26a254159a37395a916287b06949dc1f 832 PANTHER PTHR12563:SF14 1 130 0.0 T 13-09-2016 THL1_RS22735 26a254159a37395a916287b06949dc1f 832 PANTHER PTHR12563:SF14 149 823 0.0 T 13-09-2016 THL1_RS22735 26a254159a37395a916287b06949dc1f 832 Pfam PF01553 Acyltransferase 288 428 3.7E-21 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS22735 26a254159a37395a916287b06949dc1f 832 SMART SM00563 304 431 5.4E-27 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS22735 26a254159a37395a916287b06949dc1f 832 PIRSF PIRSF000437 21 826 1.4E-297 T 13-09-2016 IPR022284 Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase GO:0008374|GO:0044255 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00557 THL1_RS22735 26a254159a37395a916287b06949dc1f 832 PIRSF PIRSF500064 4 827 0.0 T 13-09-2016 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00557 THL1_RS22735 26a254159a37395a916287b06949dc1f 832 TIGRFAM TIGR03703 plsB: glycerol-3-phosphate O-acyltransferase 14 812 0.0 T 13-09-2016 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00557 THL1_RS22735 26a254159a37395a916287b06949dc1f 832 Hamap MF_00393 Glycerol-3-phosphate acyltransferase [plsB]. 15 816 30.359 T 13-09-2016 IPR028354 Glycerol-3-phosphate acyltransferase, PlsB GO:0004366|GO:0005886|GO:0008654 KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00557 THL1_RS18770 c148374c24e35125f75524a1c172cac2 506 Pfam PF13229 Right handed beta helix region 262 407 5.3E-13 T 13-09-2016 THL1_RS18770 c148374c24e35125f75524a1c172cac2 506 SMART SM00722 226 386 1.3E-7 T 13-09-2016 IPR006633 Carbohydrate-binding/sugar hydrolysis domain THL1_RS18770 c148374c24e35125f75524a1c172cac2 506 SMART SM00710 293 316 2100.0 T 13-09-2016 IPR006626 Parallel beta-helix repeat THL1_RS18770 c148374c24e35125f75524a1c172cac2 506 SMART SM00710 269 291 11.0 T 13-09-2016 IPR006626 Parallel beta-helix repeat THL1_RS18770 c148374c24e35125f75524a1c172cac2 506 SMART SM00710 207 234 5500.0 T 13-09-2016 IPR006626 Parallel beta-helix repeat THL1_RS18770 c148374c24e35125f75524a1c172cac2 506 SMART SM00710 247 268 7800.0 T 13-09-2016 IPR006626 Parallel beta-helix repeat THL1_RS18770 c148374c24e35125f75524a1c172cac2 506 SMART SM00710 342 364 2000.0 T 13-09-2016 IPR006626 Parallel beta-helix repeat THL1_RS18770 c148374c24e35125f75524a1c172cac2 506 SMART SM00710 365 387 260.0 T 13-09-2016 IPR006626 Parallel beta-helix repeat THL1_RS18770 c148374c24e35125f75524a1c172cac2 506 SMART SM00710 318 340 220.0 T 13-09-2016 IPR006626 Parallel beta-helix repeat THL1_RS18770 c148374c24e35125f75524a1c172cac2 506 SUPERFAMILY SSF51126 130 428 1.73E-31 T 13-09-2016 IPR011050 Pectin lyase fold/virulence factor THL1_RS18770 c148374c24e35125f75524a1c172cac2 506 Gene3D G3DSA:2.160.20.10 254 407 2.0E-12 T 13-09-2016 IPR012334 Pectin lyase fold THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 Gene3D G3DSA:1.10.287.130 750 805 3.4E-9 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 SMART SM00387 863 975 1.1E-34 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 PANTHER PTHR24423:SF497 28 43 3.8E-111 T 13-09-2016 THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 PANTHER PTHR24423:SF497 628 973 3.8E-111 T 13-09-2016 THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 SUPERFAMILY SSF55874 815 974 3.93E-38 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 Gene3D G3DSA:3.30.565.10 806 973 4.5E-40 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 SUPERFAMILY SSF47384 749 817 1.75E-10 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 PANTHER PTHR24423 28 43 3.8E-111 T 13-09-2016 THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 Pfam PF00512 His Kinase A (phospho-acceptor) domain 755 818 6.9E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 SUPERFAMILY SSF55785 629 715 1.07E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 SMART SM00388 754 820 1.4E-10 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 Gene3D G3DSA:3.30.450.20 623 738 4.8E-9 T 13-09-2016 THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 SMART SM00091 630 698 0.0084 T 13-09-2016 IPR000014 PAS domain THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 PRINTS PR00344 Bacterial sensor protein C-terminal signature 900 914 1.4E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 PRINTS PR00344 Bacterial sensor protein C-terminal signature 918 928 1.4E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 PRINTS PR00344 Bacterial sensor protein C-terminal signature 959 972 1.4E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 PRINTS PR00344 Bacterial sensor protein C-terminal signature 931 949 1.4E-15 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 863 972 1.2E-21 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 Pfam PF00989 PAS fold 633 675 2.4E-5 T 13-09-2016 IPR013767 PAS fold GO:0006355 THL1_RS24285 1ff73ffc257575c4834d0e347aeaefc3 982 PANTHER PTHR24423 628 973 3.8E-111 T 13-09-2016 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 Pfam PF09334 tRNA synthetases class I (M) 39 171 7.6E-20 T 13-09-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 631 665 4.5E-7 T 13-09-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 428 584 3.3E-8 T 13-09-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 Gene3D G3DSA:3.40.50.620 5 226 1.3E-135 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 Gene3D G3DSA:3.40.50.620 500 586 1.3E-135 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 Gene3D G3DSA:3.40.50.620 631 658 1.3E-135 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 410 8.7E-67 T 13-09-2016 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 PANTHER PTHR11946:SF7 244 269 0.0 T 13-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 PANTHER PTHR11946:SF7 631 873 0.0 T 13-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 PANTHER PTHR11946:SF7 289 586 0.0 T 13-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 PANTHER PTHR11946:SF7 1 206 0.0 T 13-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 872 0.0 T 13-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 SUPERFAMILY SSF50677 226 424 6.91E-49 T 13-09-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 13-09-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 PRINTS PR00985 Leucyl-tRNA synthetase signature 536 558 4.7E-51 T 13-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 PRINTS PR00985 Leucyl-tRNA synthetase signature 185 198 4.7E-51 T 13-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 4.7E-51 T 13-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 PRINTS PR00985 Leucyl-tRNA synthetase signature 497 515 4.7E-51 T 13-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 4.7E-51 T 13-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 4.7E-51 T 13-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 PRINTS PR00985 Leucyl-tRNA synthetase signature 569 579 4.7E-51 T 13-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 Gene3D G3DSA:3.90.740.10 227 467 1.0E-60 T 13-09-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 SUPERFAMILY SSF52374 426 680 1.63E-151 T 13-09-2016 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 SUPERFAMILY SSF52374 5 226 1.63E-151 T 13-09-2016 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 Gene3D G3DSA:1.10.730.10 659 808 1.3E-43 T 13-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 SUPERFAMILY SSF47323 675 872 7.66E-37 T 13-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 Pfam PF08264 Anticodon-binding domain of tRNA 716 834 6.1E-17 T 13-09-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 PANTHER PTHR11946 1 206 0.0 T 13-09-2016 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 872 23.537 T 13-09-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 PANTHER PTHR11946 244 269 0.0 T 13-09-2016 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 PANTHER PTHR11946 631 873 0.0 T 13-09-2016 THL1_RS04290 6fd7dc5534db9326f460b430e4e1f3f5 873 PANTHER PTHR11946 289 586 0.0 T 13-09-2016 THL1_RS01760 b094ea61f561d02d29e04005c88af0b9 317 SUPERFAMILY SSF53850 27 303 6.06E-79 T 13-09-2016 THL1_RS01760 b094ea61f561d02d29e04005c88af0b9 317 TIGRFAM TIGR03414 ABC_choline_bnd: choline ABC transporter, periplasmic binding protein 26 310 5.5E-132 T 13-09-2016 IPR017783 ABC transporter, choline, substrate-binding protein GO:0015871|GO:0033265|GO:0042597 THL1_RS01760 b094ea61f561d02d29e04005c88af0b9 317 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 34 287 1.9E-49 T 13-09-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 THL1_RS01760 b094ea61f561d02d29e04005c88af0b9 317 PANTHER PTHR30177 25 291 6.4E-126 T 13-09-2016 THL1_RS01760 b094ea61f561d02d29e04005c88af0b9 317 PANTHER PTHR30177:SF6 25 291 6.4E-126 T 13-09-2016 THL1_RS01760 b094ea61f561d02d29e04005c88af0b9 317 Gene3D G3DSA:3.40.190.100 128 239 1.5E-16 T 13-09-2016 THL1_RS01760 b094ea61f561d02d29e04005c88af0b9 317 Gene3D G3DSA:3.40.190.10 240 302 5.4E-43 T 13-09-2016 THL1_RS01760 b094ea61f561d02d29e04005c88af0b9 317 Gene3D G3DSA:3.40.190.10 28 115 5.4E-43 T 13-09-2016 THL1_RS22500 5482534d4129702c9d6d0a0c13924b43 249 Gene3D G3DSA:3.40.1210.10 1 246 3.4E-80 T 13-09-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 THL1_RS22500 5482534d4129702c9d6d0a0c13924b43 249 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 248 38.808 T 13-09-2016 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 THL1_RS22500 5482534d4129702c9d6d0a0c13924b43 249 Pfam PF01975 Survival protein SurE 3 181 8.4E-54 T 13-09-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 THL1_RS22500 5482534d4129702c9d6d0a0c13924b43 249 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 232 3.4E-62 T 13-09-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 THL1_RS22500 5482534d4129702c9d6d0a0c13924b43 249 PANTHER PTHR30457 1 249 6.5E-90 T 13-09-2016 THL1_RS22500 5482534d4129702c9d6d0a0c13924b43 249 SUPERFAMILY SSF64167 1 247 3.53E-81 T 13-09-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 THL1_RS11965 af277bda1004e94bce772ea29ad2884b 315 SUPERFAMILY SSF101898 63 305 4.97E-17 T 13-09-2016 THL1_RS11965 af277bda1004e94bce772ea29ad2884b 315 Gene3D G3DSA:2.120.10.30 76 304 1.6E-12 T 13-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like THL1_RS04945 2a0b52680401be206f6d7d3e25b0a9e3 138 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 1 26 1.4E-7 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS04945 2a0b52680401be206f6d7d3e25b0a9e3 138 PANTHER PTHR30093 1 63 1.3E-20 T 13-09-2016 THL1_RS04945 2a0b52680401be206f6d7d3e25b0a9e3 138 Gene3D G3DSA:3.30.700.10 7 124 8.8E-20 T 13-09-2016 THL1_RS04945 2a0b52680401be206f6d7d3e25b0a9e3 138 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 28 118 6.7E-24 T 13-09-2016 IPR031982 Type IV minor pilin ComP THL1_RS04945 2a0b52680401be206f6d7d3e25b0a9e3 138 SUPERFAMILY SSF54523 7 125 1.41E-24 T 13-09-2016 THL1_RS04945 2a0b52680401be206f6d7d3e25b0a9e3 138 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 27 3.6E-9 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS24170 89d331b362dbc540d76ab54b83a0098a 334 Gene3D G3DSA:3.90.420.10 82 302 6.2E-67 T 13-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 THL1_RS24170 89d331b362dbc540d76ab54b83a0098a 334 Hamap MF_01206 Sulfoxide reductase catalytic subunit YedY [yedY]. 6 334 58.773 T 13-09-2016 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 THL1_RS24170 89d331b362dbc540d76ab54b83a0098a 334 SUPERFAMILY SSF56524 79 330 3.53E-89 T 13-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 THL1_RS24170 89d331b362dbc540d76ab54b83a0098a 334 Pfam PF00174 Oxidoreductase molybdopterin binding domain 111 269 7.6E-29 T 13-09-2016 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 THL1_RS24170 89d331b362dbc540d76ab54b83a0098a 334 PANTHER PTHR19372 13 329 4.0E-140 T 13-09-2016 THL1_RS24170 89d331b362dbc540d76ab54b83a0098a 334 PANTHER PTHR19372:SF1 13 329 4.0E-140 T 13-09-2016 THL1_RS18560 48197e61bc9bd1713aacbc709f510a0e 152 Pfam PF01381 Helix-turn-helix 11 63 1.3E-10 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS18560 48197e61bc9bd1713aacbc709f510a0e 152 Gene3D G3DSA:1.10.260.40 3 66 8.5E-14 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS18560 48197e61bc9bd1713aacbc709f510a0e 152 Gene3D G3DSA:1.10.10.60 118 148 7.1E-4 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS18560 48197e61bc9bd1713aacbc709f510a0e 152 SUPERFAMILY SSF47413 4 67 2.7E-12 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS18560 48197e61bc9bd1713aacbc709f510a0e 152 SMART SM00530 10 63 3.4E-9 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS15615 18d1393a42b7461d72d4cb1d37ecd723 713 Pfam PF00672 HAMP domain 364 432 1.6E-13 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS15615 18d1393a42b7461d72d4cb1d37ecd723 713 PANTHER PTHR32089:SF34 24 713 1.2E-240 T 13-09-2016 THL1_RS15615 18d1393a42b7461d72d4cb1d37ecd723 713 Gene3D G3DSA:3.30.450.20 101 137 8.9E-9 T 13-09-2016 THL1_RS15615 18d1393a42b7461d72d4cb1d37ecd723 713 Gene3D G3DSA:3.30.450.20 169 239 8.9E-9 T 13-09-2016 THL1_RS15615 18d1393a42b7461d72d4cb1d37ecd723 713 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 519 711 2.0E-50 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS15615 18d1393a42b7461d72d4cb1d37ecd723 713 Pfam PF02743 Cache domain 52 332 5.8E-13 T 13-09-2016 IPR033479 Double Cache domain 1 THL1_RS15615 18d1393a42b7461d72d4cb1d37ecd723 713 Gene3D G3DSA:1.10.287.950 465 682 4.1E-58 T 13-09-2016 THL1_RS15615 18d1393a42b7461d72d4cb1d37ecd723 713 SMART SM00304 382 436 2.9E-8 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS15615 18d1393a42b7461d72d4cb1d37ecd723 713 SUPERFAMILY SSF58104 404 712 7.59E-82 T 13-09-2016 THL1_RS15615 18d1393a42b7461d72d4cb1d37ecd723 713 PANTHER PTHR32089 24 713 1.2E-240 T 13-09-2016 THL1_RS15615 18d1393a42b7461d72d4cb1d37ecd723 713 SMART SM00283 451 712 1.4E-82 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS24310 53c7b7a4cca789102b7d41bdb06f0871 286 Gene3D G3DSA:3.40.50.620 1 174 7.0E-75 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS24310 53c7b7a4cca789102b7d41bdb06f0871 286 Hamap MF_00158 Pantothenate synthetase [panC]. 2 280 40.298 T 13-09-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 THL1_RS24310 53c7b7a4cca789102b7d41bdb06f0871 286 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 3 279 7.6E-101 T 13-09-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 THL1_RS24310 53c7b7a4cca789102b7d41bdb06f0871 286 SUPERFAMILY SSF52374 1 282 2.17E-105 T 13-09-2016 THL1_RS24310 53c7b7a4cca789102b7d41bdb06f0871 286 PANTHER PTHR21299 1 283 1.4E-128 T 13-09-2016 THL1_RS24310 53c7b7a4cca789102b7d41bdb06f0871 286 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 65 2.4E-7 T 13-09-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THL1_RS24310 53c7b7a4cca789102b7d41bdb06f0871 286 Pfam PF02569 Pantoate-beta-alanine ligase 4 278 7.6E-103 T 13-09-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 THL1_RS24310 53c7b7a4cca789102b7d41bdb06f0871 286 PANTHER PTHR21299:SF1 1 283 1.4E-128 T 13-09-2016 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1|UniPathway: UPA00028 THL1_RS24310 53c7b7a4cca789102b7d41bdb06f0871 286 Gene3D G3DSA:3.30.1300.10 181 282 2.9E-30 T 13-09-2016 THL1_RS11390 06e90f7c40a1829dbfb8c6856dff73e1 229 Gene3D G3DSA:3.90.226.10 2 224 8.4E-37 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS11390 06e90f7c40a1829dbfb8c6856dff73e1 229 PANTHER PTHR11941 1 229 1.2E-128 T 13-09-2016 THL1_RS11390 06e90f7c40a1829dbfb8c6856dff73e1 229 SUPERFAMILY SSF52096 3 226 1.82E-45 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS11390 06e90f7c40a1829dbfb8c6856dff73e1 229 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 227 3.4E-31 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS11390 06e90f7c40a1829dbfb8c6856dff73e1 229 PANTHER PTHR11941:SF50 1 229 1.2E-128 T 13-09-2016 THL1_RS14785 6c203fcb9dd675d84a870a833821505f 347 Pfam PF04958 Arginine N-succinyltransferase beta subunit 1 333 2.1E-127 T 13-09-2016 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109|UniPathway: UPA00185 THL1_RS14785 6c203fcb9dd675d84a870a833821505f 347 PANTHER PTHR30420:SF1 1 342 5.0E-165 T 13-09-2016 THL1_RS14785 6c203fcb9dd675d84a870a833821505f 347 SUPERFAMILY SSF55729 1 334 4.81E-121 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS14785 6c203fcb9dd675d84a870a833821505f 347 PANTHER PTHR30420 1 342 5.0E-165 T 13-09-2016 THL1_RS14785 6c203fcb9dd675d84a870a833821505f 347 TIGRFAM TIGR03244 arg_catab_AstA: arginine N-succinyltransferase 2 334 7.7E-142 T 13-09-2016 IPR017650 Arginine N-succinyltransferase GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109|UniPathway: UPA00185 THL1_RS14785 6c203fcb9dd675d84a870a833821505f 347 TIGRFAM TIGR03243 arg_catab_AOST: arginine and ornithine succinyltransferase subunits 2 334 1.1E-132 T 13-09-2016 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109|UniPathway: UPA00185 THL1_RS14785 6c203fcb9dd675d84a870a833821505f 347 Gene3D G3DSA:2.40.40.20 278 334 3.1E-5 T 13-09-2016 THL1_RS14785 6c203fcb9dd675d84a870a833821505f 347 Gene3D G3DSA:3.40.630.30 112 131 1.2E-5 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS14785 6c203fcb9dd675d84a870a833821505f 347 Gene3D G3DSA:3.40.630.30 1 77 1.2E-5 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS17590 68ef4f14a81a424775e86a749de81610 177 Gene3D G3DSA:3.10.20.80 10 84 1.1E-32 T 13-09-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 THL1_RS17590 68ef4f14a81a424775e86a749de81610 177 SUPERFAMILY SSF54364 12 84 1.44E-26 T 13-09-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 THL1_RS17590 68ef4f14a81a424775e86a749de81610 177 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 13 176 1.4E-65 T 13-09-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 THL1_RS17590 68ef4f14a81a424775e86a749de81610 177 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 3 176 29.624 T 13-09-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 THL1_RS17590 68ef4f14a81a424775e86a749de81610 177 PANTHER PTHR10938 2 177 3.7E-66 T 13-09-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 THL1_RS17590 68ef4f14a81a424775e86a749de81610 177 Gene3D G3DSA:3.30.110.10 85 176 9.0E-40 T 13-09-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 THL1_RS17590 68ef4f14a81a424775e86a749de81610 177 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 13 79 2.0E-29 T 13-09-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 THL1_RS17590 68ef4f14a81a424775e86a749de81610 177 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 90 174 7.8E-38 T 13-09-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 THL1_RS17590 68ef4f14a81a424775e86a749de81610 177 SUPERFAMILY SSF55200 90 175 5.89E-33 T 13-09-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 THL1_RS20520 7823c7a9c1ca6a6203f3121620dafd28 256 SUPERFAMILY SSF52096 3 256 2.87E-76 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20520 7823c7a9c1ca6a6203f3121620dafd28 256 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 97 117 - T 13-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THL1_RS20520 7823c7a9c1ca6a6203f3121620dafd28 256 PANTHER PTHR11941 1 253 3.5E-74 T 13-09-2016 THL1_RS20520 7823c7a9c1ca6a6203f3121620dafd28 256 Gene3D G3DSA:3.90.226.10 2 254 5.1E-75 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20520 7823c7a9c1ca6a6203f3121620dafd28 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 255 3.5E-62 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS21155 8ec9477d7789cf7b9a459f777a9b09bf 411 PIRSF PIRSF000726 59 410 2.9E-151 T 13-09-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 THL1_RS21155 8ec9477d7789cf7b9a459f777a9b09bf 411 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 13-09-2016 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 THL1_RS21155 8ec9477d7789cf7b9a459f777a9b09bf 411 Pfam PF01842 ACT domain 267 324 5.8E-10 T 13-09-2016 IPR002912 ACT domain GO:0008152|GO:0016597 THL1_RS21155 8ec9477d7789cf7b9a459f777a9b09bf 411 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 403 7.8E-133 T 13-09-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 THL1_RS21155 8ec9477d7789cf7b9a459f777a9b09bf 411 PANTHER PTHR21499 1 411 1.3E-178 T 13-09-2016 THL1_RS21155 8ec9477d7789cf7b9a459f777a9b09bf 411 Pfam PF13840 ACT domain 339 398 7.6E-15 T 13-09-2016 IPR027795 GATS-like ACT domain THL1_RS21155 8ec9477d7789cf7b9a459f777a9b09bf 411 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 402 9.4E-120 T 13-09-2016 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 THL1_RS21155 8ec9477d7789cf7b9a459f777a9b09bf 411 Pfam PF00696 Amino acid kinase family 3 229 1.8E-50 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS21155 8ec9477d7789cf7b9a459f777a9b09bf 411 SUPERFAMILY SSF55021 329 404 4.84E-25 T 13-09-2016 THL1_RS21155 8ec9477d7789cf7b9a459f777a9b09bf 411 PANTHER PTHR21499:SF27 1 411 1.3E-178 T 13-09-2016 THL1_RS21155 8ec9477d7789cf7b9a459f777a9b09bf 411 Gene3D G3DSA:3.40.1160.10 1 246 1.7E-75 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS21155 8ec9477d7789cf7b9a459f777a9b09bf 411 SUPERFAMILY SSF55021 248 326 4.12E-18 T 13-09-2016 THL1_RS21155 8ec9477d7789cf7b9a459f777a9b09bf 411 SUPERFAMILY SSF53633 4 241 2.88E-74 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS18595 b65827cab3a54bcea6351766f5a4487c 298 SUPERFAMILY SSF116734 3 105 5.07E-20 T 13-09-2016 THL1_RS18595 b65827cab3a54bcea6351766f5a4487c 298 SUPERFAMILY SSF116734 99 297 1.28E-28 T 13-09-2016 THL1_RS18595 b65827cab3a54bcea6351766f5a4487c 298 Pfam PF01420 Type I restriction modification DNA specificity domain 106 275 3.5E-6 T 13-09-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THL1_RS08120 ba264e95b79d8d4c6ff8fcf82ad80308 401 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 7 399 49.696 T 13-09-2016 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 THL1_RS08120 ba264e95b79d8d4c6ff8fcf82ad80308 401 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 12 397 2.6E-152 T 13-09-2016 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 THL1_RS08120 ba264e95b79d8d4c6ff8fcf82ad80308 401 SUPERFAMILY SSF54675 9 140 1.26E-40 T 13-09-2016 THL1_RS08120 ba264e95b79d8d4c6ff8fcf82ad80308 401 SUPERFAMILY SSF51690 122 395 8.63E-90 T 13-09-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 THL1_RS08120 ba264e95b79d8d4c6ff8fcf82ad80308 401 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 171 398 3.0E-85 T 13-09-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 THL1_RS08120 ba264e95b79d8d4c6ff8fcf82ad80308 401 PANTHER PTHR11098 1 397 3.3E-204 T 13-09-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 THL1_RS08120 ba264e95b79d8d4c6ff8fcf82ad80308 401 Gene3D G3DSA:3.20.140.10 7 380 4.1E-143 T 13-09-2016 THL1_RS08120 ba264e95b79d8d4c6ff8fcf82ad80308 401 PIRSF PIRSF000484 1 401 3.5E-62 T 13-09-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 THL1_RS08120 ba264e95b79d8d4c6ff8fcf82ad80308 401 PANTHER PTHR11098:SF16 1 397 3.3E-204 T 13-09-2016 THL1_RS11060 aa7defd9d69b8e024cf626b84f3c2d7c 222 PANTHER PTHR24220:SF430 3 222 4.0E-89 T 13-09-2016 THL1_RS11060 aa7defd9d69b8e024cf626b84f3c2d7c 222 SUPERFAMILY SSF52540 1 219 4.39E-59 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11060 aa7defd9d69b8e024cf626b84f3c2d7c 222 Pfam PF00005 ABC transporter 21 166 1.6E-28 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS11060 aa7defd9d69b8e024cf626b84f3c2d7c 222 PANTHER PTHR24220 3 222 4.0E-89 T 13-09-2016 THL1_RS11060 aa7defd9d69b8e024cf626b84f3c2d7c 222 SMART SM00382 30 219 1.6E-11 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS11060 aa7defd9d69b8e024cf626b84f3c2d7c 222 Gene3D G3DSA:3.40.50.300 1 221 4.6E-59 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26560 e80618e20d960924e8bf8f70646952ea 250 Gene3D G3DSA:1.10.10.10 19 92 1.6E-26 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS26560 e80618e20d960924e8bf8f70646952ea 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 85 2.1E-20 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS26560 e80618e20d960924e8bf8f70646952ea 250 Gene3D G3DSA:3.40.1410.10 103 239 2.9E-53 T 13-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain THL1_RS26560 e80618e20d960924e8bf8f70646952ea 250 SMART SM00866 106 243 8.3E-37 T 13-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 THL1_RS26560 e80618e20d960924e8bf8f70646952ea 250 SMART SM00345 26 85 4.8E-21 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS26560 e80618e20d960924e8bf8f70646952ea 250 SUPERFAMILY SSF64288 73 248 7.69E-45 T 13-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain THL1_RS26560 e80618e20d960924e8bf8f70646952ea 250 TIGRFAM TIGR02018 his_ut_repres: histidine utilization repressor 21 249 2.2E-108 T 13-09-2016 IPR010248 Histidine utilization repressor GO:0003677|GO:0006547|GO:0045892 UniPathway: UPA00379 THL1_RS26560 e80618e20d960924e8bf8f70646952ea 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 4.7E-9 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS26560 e80618e20d960924e8bf8f70646952ea 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 4.7E-9 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS26560 e80618e20d960924e8bf8f70646952ea 250 Pfam PF07702 UTRA domain 106 243 9.3E-36 T 13-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 THL1_RS26560 e80618e20d960924e8bf8f70646952ea 250 PANTHER PTHR11751 18 109 2.8E-50 T 13-09-2016 THL1_RS26560 e80618e20d960924e8bf8f70646952ea 250 PANTHER PTHR11751:SF364 18 109 2.8E-50 T 13-09-2016 THL1_RS26560 e80618e20d960924e8bf8f70646952ea 250 SUPERFAMILY SSF46785 19 109 4.72E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20780 982a2b5434b23e4e654d063bdae9dd11 140 PANTHER PTHR30574:SF1 7 133 4.8E-22 T 13-09-2016 THL1_RS20780 982a2b5434b23e4e654d063bdae9dd11 140 PANTHER PTHR30574 7 133 4.8E-22 T 13-09-2016 THL1_RS21455 3f01c471f101341adff4674a636c71d2 450 Pfam PF02321 Outer membrane efflux protein 237 420 1.9E-24 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS21455 3f01c471f101341adff4674a636c71d2 450 Pfam PF02321 Outer membrane efflux protein 24 216 1.5E-24 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS21455 3f01c471f101341adff4674a636c71d2 450 PANTHER PTHR30026 1 446 1.2E-69 T 13-09-2016 THL1_RS21455 3f01c471f101341adff4674a636c71d2 450 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 20 427 7.5E-93 T 13-09-2016 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 THL1_RS21455 3f01c471f101341adff4674a636c71d2 450 Gene3D G3DSA:1.20.1600.10 19 424 7.4E-67 T 13-09-2016 THL1_RS21455 3f01c471f101341adff4674a636c71d2 450 PANTHER PTHR30026:SF4 1 446 1.2E-69 T 13-09-2016 THL1_RS21455 3f01c471f101341adff4674a636c71d2 450 SUPERFAMILY SSF56954 1 423 1.57E-82 T 13-09-2016 THL1_RS19755 4ab1c75bd36ee99756c36300e38b5862 386 PANTHER PTHR23521 2 375 1.8E-107 T 13-09-2016 THL1_RS19755 4ab1c75bd36ee99756c36300e38b5862 386 Pfam PF07690 Major Facilitator Superfamily 205 371 1.2E-17 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS19755 4ab1c75bd36ee99756c36300e38b5862 386 Gene3D G3DSA:1.20.1250.20 6 173 1.3E-8 T 13-09-2016 THL1_RS19755 4ab1c75bd36ee99756c36300e38b5862 386 Gene3D G3DSA:1.20.1250.20 195 371 1.2E-24 T 13-09-2016 THL1_RS19755 4ab1c75bd36ee99756c36300e38b5862 386 PANTHER PTHR23521:SF2 2 375 1.8E-107 T 13-09-2016 THL1_RS19755 4ab1c75bd36ee99756c36300e38b5862 386 SUPERFAMILY SSF103473 6 371 2.88E-40 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS14975 83a3e6a09818a87fb17dd2c64e9b5bf6 429 TIGRFAM TIGR01629 rep_II_X: phage/plasmid replication protein, gene II/X family 346 425 3.9E-22 T 13-09-2016 IPR006516 Replication-associated protein G2P GO:0006260 THL1_RS14975 83a3e6a09818a87fb17dd2c64e9b5bf6 429 TIGRFAM TIGR01629 rep_II_X: phage/plasmid replication protein, gene II/X family 3 315 3.9E-58 T 13-09-2016 IPR006516 Replication-associated protein G2P GO:0006260 THL1_RS14975 83a3e6a09818a87fb17dd2c64e9b5bf6 429 Pfam PF05144 Phage replication protein CRI 1 268 6.1E-56 T 13-09-2016 IPR022686 Replication-associated protein G2P, N-terminal GO:0006260 THL1_RS14975 83a3e6a09818a87fb17dd2c64e9b5bf6 429 Pfam PF05155 Phage X family 345 426 4.8E-19 T 13-09-2016 IPR022688 Replication-associated protein G2P, C-terminal GO:0006260 THL1_RS14915 83a3e6a09818a87fb17dd2c64e9b5bf6 429 TIGRFAM TIGR01629 rep_II_X: phage/plasmid replication protein, gene II/X family 346 425 3.9E-22 T 13-09-2016 IPR006516 Replication-associated protein G2P GO:0006260 THL1_RS14915 83a3e6a09818a87fb17dd2c64e9b5bf6 429 TIGRFAM TIGR01629 rep_II_X: phage/plasmid replication protein, gene II/X family 3 315 3.9E-58 T 13-09-2016 IPR006516 Replication-associated protein G2P GO:0006260 THL1_RS14915 83a3e6a09818a87fb17dd2c64e9b5bf6 429 Pfam PF05144 Phage replication protein CRI 1 268 6.1E-56 T 13-09-2016 IPR022686 Replication-associated protein G2P, N-terminal GO:0006260 THL1_RS14915 83a3e6a09818a87fb17dd2c64e9b5bf6 429 Pfam PF05155 Phage X family 345 426 4.8E-19 T 13-09-2016 IPR022688 Replication-associated protein G2P, C-terminal GO:0006260 THL1_RS04765 0b49be948bf55372d8206ef029f4822b 444 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 55 183 3.2E-49 T 13-09-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 THL1_RS04765 0b49be948bf55372d8206ef029f4822b 444 Gene3D G3DSA:3.40.50.720 207 369 1.7E-60 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS04765 0b49be948bf55372d8206ef029f4822b 444 SMART SM00839 202 442 8.0E-92 T 13-09-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 THL1_RS04765 0b49be948bf55372d8206ef029f4822b 444 SUPERFAMILY SSF53223 6 194 8.32E-74 T 13-09-2016 THL1_RS04765 0b49be948bf55372d8206ef029f4822b 444 PANTHER PTHR11606:SF4 1 444 9.3E-247 T 13-09-2016 THL1_RS04765 0b49be948bf55372d8206ef029f4822b 444 SUPERFAMILY SSF51735 200 443 6.34E-77 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS04765 0b49be948bf55372d8206ef029f4822b 444 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 200 442 1.2E-85 T 13-09-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 THL1_RS04765 0b49be948bf55372d8206ef029f4822b 444 Gene3D G3DSA:1.10.285.10 370 444 2.8E-29 T 13-09-2016 THL1_RS04765 0b49be948bf55372d8206ef029f4822b 444 Gene3D G3DSA:1.10.285.10 5 65 7.5E-27 T 13-09-2016 THL1_RS04765 0b49be948bf55372d8206ef029f4822b 444 Gene3D G3DSA:3.40.192.10 66 186 7.9E-61 T 13-09-2016 THL1_RS04765 0b49be948bf55372d8206ef029f4822b 444 PIRSF PIRSF000185 20 444 2.2E-117 T 13-09-2016 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 THL1_RS04765 0b49be948bf55372d8206ef029f4822b 444 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 120 133 - T 13-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 THL1_RS04765 0b49be948bf55372d8206ef029f4822b 444 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 191 213 2.9E-32 T 13-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 THL1_RS04765 0b49be948bf55372d8206ef029f4822b 444 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 233 253 2.9E-32 T 13-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 THL1_RS04765 0b49be948bf55372d8206ef029f4822b 444 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 112 126 2.9E-32 T 13-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 THL1_RS04765 0b49be948bf55372d8206ef029f4822b 444 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 369 380 2.9E-32 T 13-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 THL1_RS04765 0b49be948bf55372d8206ef029f4822b 444 PANTHER PTHR11606 1 444 9.3E-247 T 13-09-2016 THL1_RS27295 5efb6aac306fb9bacebdda9f780a463c 325 Pfam PF00107 Zinc-binding dehydrogenase 151 273 5.3E-34 T 13-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THL1_RS27295 5efb6aac306fb9bacebdda9f780a463c 325 Gene3D G3DSA:3.40.50.720 146 262 2.8E-38 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS27295 5efb6aac306fb9bacebdda9f780a463c 325 PANTHER PTHR11695 15 323 1.6E-143 T 13-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 THL1_RS27295 5efb6aac306fb9bacebdda9f780a463c 325 SUPERFAMILY SSF51735 111 278 6.85E-54 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS27295 5efb6aac306fb9bacebdda9f780a463c 325 SUPERFAMILY SSF50129 1 140 1.25E-41 T 13-09-2016 IPR011032 GroES-like THL1_RS27295 5efb6aac306fb9bacebdda9f780a463c 325 Gene3D G3DSA:3.90.180.10 1 145 2.2E-51 T 13-09-2016 IPR011032 GroES-like THL1_RS27295 5efb6aac306fb9bacebdda9f780a463c 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 4.7E-11 T 13-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THL1_RS27295 5efb6aac306fb9bacebdda9f780a463c 325 SMART SM00829 10 322 2.6E-57 T 13-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THL1_RS27295 5efb6aac306fb9bacebdda9f780a463c 325 PANTHER PTHR11695:SF31 15 323 1.6E-143 T 13-09-2016 THL1_RS14210 0468db2c924cb49430dd87535c7edd40 215 PANTHER PTHR14136:SF0 33 192 1.5E-31 T 13-09-2016 THL1_RS14210 0468db2c924cb49430dd87535c7edd40 215 PANTHER PTHR14136 33 192 1.5E-31 T 13-09-2016 THL1_RS14210 0468db2c924cb49430dd87535c7edd40 215 SUPERFAMILY SSF141571 40 208 2.59E-39 T 13-09-2016 THL1_RS14210 0468db2c924cb49430dd87535c7edd40 215 Pfam PF13599 Pentapeptide repeats (9 copies) 142 207 7.0E-9 T 13-09-2016 IPR001646 Pentapeptide repeat THL1_RS14210 0468db2c924cb49430dd87535c7edd40 215 Pfam PF00805 Pentapeptide repeats (8 copies) 42 80 7.6E-10 T 13-09-2016 IPR001646 Pentapeptide repeat THL1_RS14035 328f689e780c74f20794f7a7630eec1e 371 SUPERFAMILY SSF53850 52 365 1.47E-52 T 13-09-2016 THL1_RS14035 328f689e780c74f20794f7a7630eec1e 371 PANTHER PTHR30222 14 364 3.6E-50 T 13-09-2016 THL1_RS14035 328f689e780c74f20794f7a7630eec1e 371 Gene3D G3DSA:3.40.190.10 169 310 3.9E-27 T 13-09-2016 THL1_RS14035 328f689e780c74f20794f7a7630eec1e 371 Pfam PF13416 Bacterial extracellular solute-binding protein 72 325 8.4E-34 T 13-09-2016 THL1_RS14035 328f689e780c74f20794f7a7630eec1e 371 Gene3D G3DSA:3.40.190.10 54 168 2.2E-10 T 13-09-2016 THL1_RS14035 328f689e780c74f20794f7a7630eec1e 371 PANTHER PTHR30222:SF2 14 364 3.6E-50 T 13-09-2016 THL1_RS18330 0a027e5ecbdceebad4679abe9208639f 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.2E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18330 0a027e5ecbdceebad4679abe9208639f 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.2E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18330 0a027e5ecbdceebad4679abe9208639f 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.2E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18330 0a027e5ecbdceebad4679abe9208639f 253 PANTHER PTHR24321:SF6 3 252 2.3E-55 T 13-09-2016 THL1_RS18330 0a027e5ecbdceebad4679abe9208639f 253 SUPERFAMILY SSF51735 1 252 2.0E-82 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18330 0a027e5ecbdceebad4679abe9208639f 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.0E-45 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18330 0a027e5ecbdceebad4679abe9208639f 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.0E-45 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18330 0a027e5ecbdceebad4679abe9208639f 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 6.0E-45 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18330 0a027e5ecbdceebad4679abe9208639f 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 6.0E-45 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18330 0a027e5ecbdceebad4679abe9208639f 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 6.0E-45 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18330 0a027e5ecbdceebad4679abe9208639f 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 6.0E-45 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18330 0a027e5ecbdceebad4679abe9208639f 253 Gene3D G3DSA:3.40.50.720 1 251 3.5E-86 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18330 0a027e5ecbdceebad4679abe9208639f 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS18330 0a027e5ecbdceebad4679abe9208639f 253 PANTHER PTHR24321 3 252 2.3E-55 T 13-09-2016 THL1_RS18330 0a027e5ecbdceebad4679abe9208639f 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 1.2E-71 T 13-09-2016 THL1_RS23995 bb139cead321ced18d9c400bd12129cc 283 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 6 280 1.9E-84 T 13-09-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS23995 bb139cead321ced18d9c400bd12129cc 283 Pfam PF00288 GHMP kinases N terminal domain 88 145 5.7E-10 T 13-09-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 THL1_RS23995 bb139cead321ced18d9c400bd12129cc 283 PANTHER PTHR20861 5 278 3.7E-92 T 13-09-2016 THL1_RS23995 bb139cead321ced18d9c400bd12129cc 283 Hamap MF_00061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 6 272 33.202 T 13-09-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS23995 bb139cead321ced18d9c400bd12129cc 283 Gene3D G3DSA:3.30.70.890 162 279 2.7E-39 T 13-09-2016 IPR013750 GHMP kinase, C-terminal domain THL1_RS23995 bb139cead321ced18d9c400bd12129cc 283 Pfam PF08544 GHMP kinases C terminal 196 262 1.0E-7 T 13-09-2016 IPR013750 GHMP kinase, C-terminal domain THL1_RS23995 bb139cead321ced18d9c400bd12129cc 283 SUPERFAMILY SSF54211 7 159 3.72E-45 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS23995 bb139cead321ced18d9c400bd12129cc 283 PANTHER PTHR20861:SF2 5 278 3.7E-92 T 13-09-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS23995 bb139cead321ced18d9c400bd12129cc 283 PIRSF PIRSF010376 4 280 4.7E-86 T 13-09-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS23995 bb139cead321ced18d9c400bd12129cc 283 Gene3D G3DSA:3.30.230.10 8 161 1.7E-52 T 13-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THL1_RS23995 bb139cead321ced18d9c400bd12129cc 283 SUPERFAMILY SSF55060 162 279 2.64E-34 T 13-09-2016 IPR013750 GHMP kinase, C-terminal domain THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 PANTHER PTHR22912 4 459 3.8E-261 T 13-09-2016 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 PANTHER PTHR22912:SF93 4 459 3.8E-261 T 13-09-2016 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 Gene3D G3DSA:3.50.50.60 143 333 2.1E-50 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 PIRSF PIRSF000350 2 459 6.0E-65 T 13-09-2016 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 344 455 6.7E-29 T 13-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 SUPERFAMILY SSF55424 342 461 2.58E-28 T 13-09-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 Gene3D G3DSA:3.50.50.60 5 142 7.4E-30 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 SUPERFAMILY SSF51905 4 318 1.4E-56 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 9.5E-31 T 13-09-2016 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 290 312 9.5E-31 T 13-09-2016 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 9.5E-31 T 13-09-2016 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 9.5E-31 T 13-09-2016 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 9.5E-31 T 13-09-2016 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 Gene3D G3DSA:3.30.390.30 343 456 6.8E-30 T 13-09-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 325 9.8E-63 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 7.2E-52 T 13-09-2016 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 305 312 7.2E-52 T 13-09-2016 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 7.2E-52 T 13-09-2016 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 340 361 7.2E-52 T 13-09-2016 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 7.2E-52 T 13-09-2016 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 40 55 7.2E-52 T 13-09-2016 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 405 420 7.2E-52 T 13-09-2016 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 7.2E-52 T 13-09-2016 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 7.2E-52 T 13-09-2016 THL1_RS10730 115196ae18e24f0074519de48ab74a00 464 Hamap MF_00247 Soluble pyridine nucleotide transhydrogenase [sthA]. 1 464 72.561 T 13-09-2016 IPR022962 Soluble pyridine nucleotide transhydrogenase GO:0003957|GO:0055114 KEGG: 00760+1.6.1.1|MetaCyc: PWY-5083 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 101 351 9.3E-46 T 13-09-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 356 565 1.8E-25 T 13-09-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PRINTS PR01180 Arginine decarboxylase signature 153 168 4.2E-70 T 13-09-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PRINTS PR01180 Arginine decarboxylase signature 179 200 4.2E-70 T 13-09-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PRINTS PR01180 Arginine decarboxylase signature 75 90 4.2E-70 T 13-09-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PRINTS PR01180 Arginine decarboxylase signature 203 225 4.2E-70 T 13-09-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PRINTS PR01180 Arginine decarboxylase signature 546 567 4.2E-70 T 13-09-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PRINTS PR01180 Arginine decarboxylase signature 468 489 4.2E-70 T 13-09-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PRINTS PR01180 Arginine decarboxylase signature 99 113 4.2E-70 T 13-09-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PRINTS PR01180 Arginine decarboxylase signature 330 347 4.2E-70 T 13-09-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PRINTS PR01180 Arginine decarboxylase signature 493 518 4.2E-70 T 13-09-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PANTHER PTHR11482:SF36 443 601 1.7E-253 T 13-09-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PANTHER PTHR11482:SF36 1 373 1.7E-253 T 13-09-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 SUPERFAMILY SSF51419 75 352 6.54E-68 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 Gene3D G3DSA:2.40.37.10 459 591 4.9E-15 T 13-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 Gene3D G3DSA:2.40.37.10 339 363 4.9E-15 T 13-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 TIGRFAM TIGR01273 speA: arginine decarboxylase 14 636 1.5E-269 T 13-09-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PANTHER PTHR11482 443 601 1.7E-253 T 13-09-2016 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PANTHER PTHR11482 1 373 1.7E-253 T 13-09-2016 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 546 559 7.7E-16 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 340 359 7.7E-16 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 246 259 7.7E-16 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 130 142 7.7E-16 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 107 125 7.7E-16 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 Hamap MF_01417 Biosynthetic arginine decarboxylase [speA]. 12 637 42.288 T 13-09-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 SUPERFAMILY SSF50621 461 571 8.37E-7 T 13-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 PIRSF PIRSF001336 1 637 4.3E-251 T 13-09-2016 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 282 297 - T 13-09-2016 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Reactome: REACT_13 THL1_RS25425 d31c128115245f03e4c7d991bfc00012 637 Gene3D G3DSA:3.20.20.10 77 338 1.8E-59 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS22665 724a82a1c6b8b9edef1d9c6ab2fedba9 344 TIGRFAM TIGR03536 DapD_gpp: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 5 344 7.8E-190 T 13-09-2016 IPR019876 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, gammaproteobacteria KEGG: 00300+2.3.1.117|UniPathway: UPA00034 THL1_RS22665 724a82a1c6b8b9edef1d9c6ab2fedba9 344 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 4 341 44.178 T 13-09-2016 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117|UniPathway: UPA00034 THL1_RS22665 724a82a1c6b8b9edef1d9c6ab2fedba9 344 Gene3D G3DSA:2.160.10.10 173 341 1.5E-31 T 13-09-2016 THL1_RS22665 724a82a1c6b8b9edef1d9c6ab2fedba9 344 SUPERFAMILY SSF51161 97 300 1.52E-34 T 13-09-2016 IPR011004 Trimeric LpxA-like THL1_RS22665 724a82a1c6b8b9edef1d9c6ab2fedba9 344 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 132 172 5.0E-16 T 13-09-2016 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117|UniPathway: UPA00034 THL1_RS22665 724a82a1c6b8b9edef1d9c6ab2fedba9 344 Gene3D G3DSA:3.30.60.70 132 172 1.2E-18 T 13-09-2016 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117|UniPathway: UPA00034 THL1_RS22665 724a82a1c6b8b9edef1d9c6ab2fedba9 344 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 254 286 3.7E-12 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS01505 6bd1ea14e478089b839582d9d1354512 188 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 6 188 36.427 T 13-09-2016 IPR003774 Protein of unknown function UPF0301 THL1_RS01505 6bd1ea14e478089b839582d9d1354512 188 PANTHER PTHR30327 3 188 9.0E-65 T 13-09-2016 THL1_RS01505 6bd1ea14e478089b839582d9d1354512 188 Gene3D G3DSA:3.40.1740.10 132 178 1.6E-32 T 13-09-2016 THL1_RS01505 6bd1ea14e478089b839582d9d1354512 188 Gene3D G3DSA:3.40.1740.10 4 45 1.6E-32 T 13-09-2016 THL1_RS01505 6bd1ea14e478089b839582d9d1354512 188 Gene3D G3DSA:3.30.70.1300 46 131 3.8E-22 T 13-09-2016 THL1_RS01505 6bd1ea14e478089b839582d9d1354512 188 PANTHER PTHR30327:SF1 3 188 9.0E-65 T 13-09-2016 THL1_RS01505 6bd1ea14e478089b839582d9d1354512 188 Pfam PF02622 Uncharacterized ACR, COG1678 17 175 1.1E-45 T 13-09-2016 IPR003774 Protein of unknown function UPF0301 THL1_RS01505 6bd1ea14e478089b839582d9d1354512 188 SUPERFAMILY SSF143456 7 188 1.2E-61 T 13-09-2016 THL1_RS11120 1aa06f4a89ec95b71024e1afbf811352 113 PANTHER PTHR33204 1 104 1.2E-40 T 13-09-2016 THL1_RS11120 1aa06f4a89ec95b71024e1afbf811352 113 PANTHER PTHR33204:SF8 1 104 1.2E-40 T 13-09-2016 THL1_RS11120 1aa06f4a89ec95b71024e1afbf811352 113 SUPERFAMILY SSF46785 11 104 2.37E-30 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11120 1aa06f4a89ec95b71024e1afbf811352 113 Gene3D G3DSA:1.10.10.10 6 104 5.0E-39 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11120 1aa06f4a89ec95b71024e1afbf811352 113 Pfam PF01638 HxlR-like helix-turn-helix 21 104 2.0E-33 T 13-09-2016 IPR002577 Helix-turn-helix, HxlR type THL1_RS10655 b17dd344fd73b923ccedfb7b1f13ec6c 332 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 230 247 - T 13-09-2016 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 THL1_RS10655 b17dd344fd73b923ccedfb7b1f13ec6c 332 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 4 330 48.863 T 13-09-2016 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|UniPathway: UPA00544 THL1_RS10655 b17dd344fd73b923ccedfb7b1f13ec6c 332 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 6 288 2.9E-79 T 13-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 THL1_RS10655 b17dd344fd73b923ccedfb7b1f13ec6c 332 Gene3D G3DSA:3.20.20.300 5 302 7.6E-91 T 13-09-2016 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 THL1_RS10655 b17dd344fd73b923ccedfb7b1f13ec6c 332 PANTHER PTHR30480:SF7 5 291 7.4E-123 T 13-09-2016 THL1_RS10655 b17dd344fd73b923ccedfb7b1f13ec6c 332 PANTHER PTHR30480 5 291 7.4E-123 T 13-09-2016 THL1_RS10655 b17dd344fd73b923ccedfb7b1f13ec6c 332 SUPERFAMILY SSF51445 3 305 4.84E-83 T 13-09-2016 IPR017853 Glycoside hydrolase superfamily THL1_RS14670 d4c11257e89aa0e69e721a7cc1507807 257 PANTHER PTHR18966:SF152 1 250 1.4E-67 T 13-09-2016 THL1_RS14670 d4c11257e89aa0e69e721a7cc1507807 257 SUPERFAMILY SSF53850 6 254 1.09E-67 T 13-09-2016 THL1_RS14670 d4c11257e89aa0e69e721a7cc1507807 257 Gene3D G3DSA:3.40.190.10 114 210 4.9E-27 T 13-09-2016 THL1_RS14670 d4c11257e89aa0e69e721a7cc1507807 257 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 9 250 1.2E-82 T 13-09-2016 IPR005768 Lysine-arginine-ornithine-binding periplasmic protein GO:0005215|GO:0006810|GO:0030288 THL1_RS14670 d4c11257e89aa0e69e721a7cc1507807 257 Gene3D G3DSA:3.40.190.10 21 110 5.7E-43 T 13-09-2016 THL1_RS14670 d4c11257e89aa0e69e721a7cc1507807 257 Gene3D G3DSA:3.40.190.10 212 255 5.7E-43 T 13-09-2016 THL1_RS14670 d4c11257e89aa0e69e721a7cc1507807 257 PANTHER PTHR18966 1 250 1.4E-67 T 13-09-2016 THL1_RS14670 d4c11257e89aa0e69e721a7cc1507807 257 SMART SM00062 24 253 4.3E-75 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS14670 d4c11257e89aa0e69e721a7cc1507807 257 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 25 251 5.8E-63 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 Hamap MF_00505 Chaperone protein HtpG [htpG]. 5 628 32.789 T 13-09-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 PANTHER PTHR11528:SF44 2 629 0.0 T 13-09-2016 THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 PIRSF PIRSF002583 1 632 8.4E-215 T 13-09-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 PANTHER PTHR11528 2 629 0.0 T 13-09-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 Pfam PF00183 Hsp90 protein 226 627 1.6E-130 T 13-09-2016 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 SMART SM00387 30 187 1.3E-10 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 Gene3D G3DSA:3.30.565.10 8 241 7.3E-83 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 SUPERFAMILY SSF55874 8 217 9.95E-65 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 30 186 4.0E-13 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 28 37 - T 13-09-2016 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 SUPERFAMILY SSF54211 234 489 5.84E-97 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 PRINTS PR00775 90kDa heat shock protein signature 123 145 1.3E-61 T 13-09-2016 IPR020575 Heat shock protein Hsp90, N-terminal THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 PRINTS PR00775 90kDa heat shock protein signature 193 211 1.3E-61 T 13-09-2016 IPR020575 Heat shock protein Hsp90, N-terminal THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 PRINTS PR00775 90kDa heat shock protein signature 8 28 1.3E-61 T 13-09-2016 IPR020575 Heat shock protein Hsp90, N-terminal THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 PRINTS PR00775 90kDa heat shock protein signature 78 95 1.3E-61 T 13-09-2016 IPR020575 Heat shock protein Hsp90, N-terminal THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 PRINTS PR00775 90kDa heat shock protein signature 96 113 1.3E-61 T 13-09-2016 IPR020575 Heat shock protein Hsp90, N-terminal THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 PRINTS PR00775 90kDa heat shock protein signature 29 51 1.3E-61 T 13-09-2016 IPR020575 Heat shock protein Hsp90, N-terminal THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 PRINTS PR00775 90kDa heat shock protein signature 175 192 1.3E-61 T 13-09-2016 IPR020575 Heat shock protein Hsp90, N-terminal THL1_RS10940 b6a92fe8033bbe14b52e7e76558a76a1 632 SUPERFAMILY SSF110942 516 628 1.96E-35 T 13-09-2016 THL1_RS02490 00bf8ac9e6c01880a594eff73b0b84c1 316 Pfam PF13557 Putative MetA-pathway of phenol degradation 78 310 1.3E-54 T 13-09-2016 IPR025737 MetA-pathway of phenol degradation, putative THL1_RS02490 00bf8ac9e6c01880a594eff73b0b84c1 316 Gene3D G3DSA:2.40.230.30 172 253 1.6E-4 T 13-09-2016 THL1_RS10035 f6a920dbf0c5ac1804d4b774791d19ab 370 PIRSF PIRSF000148 1 370 9.4E-65 T 13-09-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 THL1_RS10035 f6a920dbf0c5ac1804d4b774791d19ab 370 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 121 2.7E-24 T 13-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THL1_RS10035 f6a920dbf0c5ac1804d4b774791d19ab 370 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 2 368 4.2E-199 T 13-09-2016 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 THL1_RS10035 f6a920dbf0c5ac1804d4b774791d19ab 370 PANTHER PTHR10174:SF116 201 370 3.2E-159 T 13-09-2016 THL1_RS10035 f6a920dbf0c5ac1804d4b774791d19ab 370 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 262 276 - T 13-09-2016 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 THL1_RS10035 f6a920dbf0c5ac1804d4b774791d19ab 370 SMART SM00859 3 122 3.3E-27 T 13-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THL1_RS10035 f6a920dbf0c5ac1804d4b774791d19ab 370 SUPERFAMILY SSF55347 134 355 2.32E-77 T 13-09-2016 THL1_RS10035 f6a920dbf0c5ac1804d4b774791d19ab 370 SUPERFAMILY SSF51735 1 147 1.68E-54 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10035 f6a920dbf0c5ac1804d4b774791d19ab 370 Gene3D G3DSA:3.30.360.10 143 351 1.8E-75 T 13-09-2016 THL1_RS10035 f6a920dbf0c5ac1804d4b774791d19ab 370 PANTHER PTHR10174 201 370 3.2E-159 T 13-09-2016 THL1_RS10035 f6a920dbf0c5ac1804d4b774791d19ab 370 PANTHER PTHR10174 103 179 3.2E-159 T 13-09-2016 THL1_RS10035 f6a920dbf0c5ac1804d4b774791d19ab 370 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 368 34.638 T 13-09-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 THL1_RS10035 f6a920dbf0c5ac1804d4b774791d19ab 370 Gene3D G3DSA:3.40.50.720 1 142 1.0E-63 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10035 f6a920dbf0c5ac1804d4b774791d19ab 370 PANTHER PTHR10174:SF116 103 179 3.2E-159 T 13-09-2016 THL1_RS10035 f6a920dbf0c5ac1804d4b774791d19ab 370 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 144 354 7.0E-62 T 13-09-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS20065 350444dcfebf2d16272b18089813346e 230 PANTHER PTHR26402:SF552 1 225 2.4E-79 T 13-09-2016 THL1_RS20065 350444dcfebf2d16272b18089813346e 230 Gene3D G3DSA:3.40.50.2300 2 119 6.4E-38 T 13-09-2016 THL1_RS20065 350444dcfebf2d16272b18089813346e 230 SMART SM00862 147 223 2.7E-18 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS20065 350444dcfebf2d16272b18089813346e 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 223 1.0E-16 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS20065 350444dcfebf2d16272b18089813346e 230 SMART SM00448 1 113 1.7E-40 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS20065 350444dcfebf2d16272b18089813346e 230 SUPERFAMILY SSF46894 123 224 2.32E-22 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS20065 350444dcfebf2d16272b18089813346e 230 SUPERFAMILY SSF52172 2 126 3.56E-39 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS20065 350444dcfebf2d16272b18089813346e 230 Pfam PF00072 Response regulator receiver domain 3 113 5.6E-26 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS20065 350444dcfebf2d16272b18089813346e 230 Gene3D G3DSA:1.10.10.10 125 225 3.4E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20065 350444dcfebf2d16272b18089813346e 230 PANTHER PTHR26402 1 225 2.4E-79 T 13-09-2016 THL1_RS01955 afaacbe62898e6da8858b2d3790e9840 362 SUPERFAMILY SSF52540 6 242 1.77E-80 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01955 afaacbe62898e6da8858b2d3790e9840 362 PANTHER PTHR24220:SF150 7 246 4.1E-113 T 13-09-2016 THL1_RS01955 afaacbe62898e6da8858b2d3790e9840 362 Gene3D G3DSA:3.40.50.300 2 235 1.0E-77 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01955 afaacbe62898e6da8858b2d3790e9840 362 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS01955 afaacbe62898e6da8858b2d3790e9840 362 SUPERFAMILY SSF50331 240 358 2.27E-14 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS01955 afaacbe62898e6da8858b2d3790e9840 362 Pfam PF00005 ABC transporter 22 163 4.1E-35 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS01955 afaacbe62898e6da8858b2d3790e9840 362 Pfam PF08402 TOBE domain 283 359 2.8E-8 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS01955 afaacbe62898e6da8858b2d3790e9840 362 PANTHER PTHR24220 7 246 4.1E-113 T 13-09-2016 THL1_RS01955 afaacbe62898e6da8858b2d3790e9840 362 SMART SM00382 30 213 5.5E-20 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS03315 d9e0fc1928101f35303d1a660a187a40 278 PANTHER PTHR22854:SF2 2 264 1.2E-112 T 13-09-2016 THL1_RS03315 d9e0fc1928101f35303d1a660a187a40 278 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 58 76 - T 13-09-2016 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 THL1_RS03315 d9e0fc1928101f35303d1a660a187a40 278 Gene3D G3DSA:3.20.20.70 5 267 4.2E-103 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS03315 d9e0fc1928101f35303d1a660a187a40 278 PANTHER PTHR22854 2 264 1.2E-112 T 13-09-2016 THL1_RS03315 d9e0fc1928101f35303d1a660a187a40 278 Pfam PF00218 Indole-3-glycerol phosphate synthase 7 256 1.7E-97 T 13-09-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 THL1_RS03315 d9e0fc1928101f35303d1a660a187a40 278 SUPERFAMILY SSF51366 14 264 1.65E-85 T 13-09-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 THL1_RS03315 d9e0fc1928101f35303d1a660a187a40 278 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 5 265 36.567 T 13-09-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 THL1_RS26370 ddb6bd4b8537a0812dea1e46e28e46be 176 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 1 172 41.308 T 13-09-2016 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 THL1_RS26370 ddb6bd4b8537a0812dea1e46e28e46be 176 SUPERFAMILY SSF56235 2 172 1.97E-55 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS26370 ddb6bd4b8537a0812dea1e46e28e46be 176 Pfam PF00227 Proteasome subunit 2 170 2.1E-20 T 13-09-2016 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: REACT_11045|Reactome: REACT_13|Reactome: REACT_13635|Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_383|Reactome: REACT_578|Reactome: REACT_6185|Reactome: REACT_6850 THL1_RS26370 ddb6bd4b8537a0812dea1e46e28e46be 176 PANTHER PTHR32194 2 176 1.2E-123 T 13-09-2016 THL1_RS26370 ddb6bd4b8537a0812dea1e46e28e46be 176 PIRSF PIRSF039093 1 175 8.6E-85 T 13-09-2016 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 THL1_RS26370 ddb6bd4b8537a0812dea1e46e28e46be 176 Gene3D G3DSA:3.60.20.10 2 173 1.2E-82 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS26370 ddb6bd4b8537a0812dea1e46e28e46be 176 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 2 172 1.1E-84 T 13-09-2016 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 THL1_RS10665 4f0444546f093351a08a3a3b85ed37c5 764 SMART SM00490 623 703 2.5E-19 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS10665 4f0444546f093351a08a3a3b85ed37c5 764 Gene3D G3DSA:3.40.50.300 287 464 2.9E-28 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10665 4f0444546f093351a08a3a3b85ed37c5 764 SUPERFAMILY SSF52540 279 506 2.57E-58 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10665 4f0444546f093351a08a3a3b85ed37c5 764 Gene3D G3DSA:3.40.50.300 591 733 2.1E-21 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10665 4f0444546f093351a08a3a3b85ed37c5 764 SUPERFAMILY SSF52540 508 757 2.37E-62 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10665 4f0444546f093351a08a3a3b85ed37c5 764 SMART SM00487 291 479 6.6E-29 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS10665 4f0444546f093351a08a3a3b85ed37c5 764 Pfam PF00271 Helicase conserved C-terminal domain 594 703 2.2E-16 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS10665 4f0444546f093351a08a3a3b85ed37c5 764 Pfam PF00176 SNF2 family N-terminal domain 311 578 6.1E-61 T 13-09-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 THL1_RS10665 4f0444546f093351a08a3a3b85ed37c5 764 PANTHER PTHR10799 282 758 1.4E-176 T 13-09-2016 THL1_RS10665 4f0444546f093351a08a3a3b85ed37c5 764 PANTHER PTHR10799 177 183 1.4E-176 T 13-09-2016 THL1_RS21940 d340725ca13b039996a748e54c111e67 204 PIRSF PIRSF037290 4 203 2.5E-76 T 13-09-2016 IPR017166 Uncharacterised conserved protein UCP037290 THL1_RS21940 d340725ca13b039996a748e54c111e67 204 SUPERFAMILY SSF52540 50 162 4.36E-33 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21940 d340725ca13b039996a748e54c111e67 204 PANTHER PTHR35369:SF1 1 204 5.2E-81 T 13-09-2016 THL1_RS21940 d340725ca13b039996a748e54c111e67 204 PANTHER PTHR35369 1 204 5.2E-81 T 13-09-2016 THL1_RS21940 d340725ca13b039996a748e54c111e67 204 Gene3D G3DSA:3.40.50.300 50 162 1.4E-41 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18260 6a3a193e70204d12b3b457ef200bb16a 363 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 13-09-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS18260 6a3a193e70204d12b3b457ef200bb16a 363 Hamap MF_00300 Chorismate synthase [aroC]. 10 351 36.614 T 13-09-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS18260 6a3a193e70204d12b3b457ef200bb16a 363 SUPERFAMILY SSF103263 4 355 9.03E-148 T 13-09-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS18260 6a3a193e70204d12b3b457ef200bb16a 363 TIGRFAM TIGR00033 aroC: chorismate synthase 10 349 1.8E-139 T 13-09-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS18260 6a3a193e70204d12b3b457ef200bb16a 363 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 13-09-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS18260 6a3a193e70204d12b3b457ef200bb16a 363 Gene3D G3DSA:3.60.150.10 9 353 1.5E-155 T 13-09-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS18260 6a3a193e70204d12b3b457ef200bb16a 363 ProSitePatterns PS00789 Chorismate synthase signature 3. 318 334 - T 13-09-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS18260 6a3a193e70204d12b3b457ef200bb16a 363 PIRSF PIRSF001456 3 359 2.4E-137 T 13-09-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS18260 6a3a193e70204d12b3b457ef200bb16a 363 PANTHER PTHR21085 2 359 1.8E-210 T 13-09-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS18260 6a3a193e70204d12b3b457ef200bb16a 363 Pfam PF01264 Chorismate synthase 10 344 1.5E-138 T 13-09-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS08695 eb4e2b5a9e9c6db864d6c10dc131d943 278 Gene3D G3DSA:1.10.10.10 218 271 0.001 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08695 eb4e2b5a9e9c6db864d6c10dc131d943 278 PIRSF PIRSF012524 1 278 2.9E-92 T 13-09-2016 IPR014464 Conserved virulence factor B THL1_RS08695 eb4e2b5a9e9c6db864d6c10dc131d943 278 PANTHER PTHR37296 1 278 2.2E-111 T 13-09-2016 THL1_RS08695 eb4e2b5a9e9c6db864d6c10dc131d943 278 SMART SM00316 146 208 0.051 T 13-09-2016 IPR022967 RNA-binding domain, S1 THL1_RS08695 eb4e2b5a9e9c6db864d6c10dc131d943 278 SMART SM00316 71 133 5.3 T 13-09-2016 IPR022967 RNA-binding domain, S1 THL1_RS08695 eb4e2b5a9e9c6db864d6c10dc131d943 278 Pfam PF13509 S1 domain 72 130 4.3E-10 T 13-09-2016 THL1_RS08695 eb4e2b5a9e9c6db864d6c10dc131d943 278 Pfam PF13509 S1 domain 4 65 9.8E-25 T 13-09-2016 THL1_RS24010 6257b237fbd4332f0119a9cacfde6c97 313 PANTHER PTHR10210:SF41 2 313 9.2E-183 T 13-09-2016 THL1_RS24010 6257b237fbd4332f0119a9cacfde6c97 313 SMART SM01400 4 121 6.8E-76 T 13-09-2016 THL1_RS24010 6257b237fbd4332f0119a9cacfde6c97 313 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 4 313 48.346 T 13-09-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 THL1_RS24010 6257b237fbd4332f0119a9cacfde6c97 313 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 4 313 5.2E-123 T 13-09-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 THL1_RS24010 6257b237fbd4332f0119a9cacfde6c97 313 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 4 121 1.0E-47 T 13-09-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 THL1_RS24010 6257b237fbd4332f0119a9cacfde6c97 313 SUPERFAMILY SSF53271 69 305 7.37E-65 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS24010 6257b237fbd4332f0119a9cacfde6c97 313 PANTHER PTHR10210 2 313 9.2E-183 T 13-09-2016 THL1_RS24010 6257b237fbd4332f0119a9cacfde6c97 313 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 129 144 - T 13-09-2016 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: REACT_474|UniPathway: UPA00087 THL1_RS24010 6257b237fbd4332f0119a9cacfde6c97 313 Pfam PF14572 Phosphoribosyl synthetase-associated domain 202 313 4.5E-34 T 13-09-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 THL1_RS24010 6257b237fbd4332f0119a9cacfde6c97 313 Gene3D G3DSA:3.40.50.2020 160 287 2.6E-55 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS24010 6257b237fbd4332f0119a9cacfde6c97 313 Gene3D G3DSA:3.40.50.2020 2 159 2.9E-73 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS08125 d09d22a885ef7a326389b90b76057ee3 848 PANTHER PTHR34218 1 848 8.4E-250 T 13-09-2016 THL1_RS08125 d09d22a885ef7a326389b90b76057ee3 848 SUPERFAMILY SSF56235 52 840 7.97E-198 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS08125 d09d22a885ef7a326389b90b76057ee3 848 Gene3D G3DSA:3.60.20.10 429 677 3.6E-90 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS08125 d09d22a885ef7a326389b90b76057ee3 848 Gene3D G3DSA:3.60.20.10 265 340 3.6E-90 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS08125 d09d22a885ef7a326389b90b76057ee3 848 Gene3D G3DSA:2.30.120.10 341 401 4.4E-19 T 13-09-2016 THL1_RS08125 d09d22a885ef7a326389b90b76057ee3 848 PIRSF PIRSF001227 13 844 1.3E-161 T 13-09-2016 IPR014395 Penicillin acylase GO:0016811 THL1_RS08125 d09d22a885ef7a326389b90b76057ee3 848 PANTHER PTHR34218:SF2 1 848 8.4E-250 T 13-09-2016 THL1_RS08125 d09d22a885ef7a326389b90b76057ee3 848 Pfam PF01804 Penicillin amidase 55 834 6.6E-193 T 13-09-2016 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 THL1_RS08125 d09d22a885ef7a326389b90b76057ee3 848 Gene3D G3DSA:1.10.439.10 40 209 1.2E-45 T 13-09-2016 IPR023343 Penicillin amidase type, domain1 GO:0016811 THL1_RS04415 f829ba3c6089fa173f7a1259135608bb 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 9.9E-20 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS04415 f829ba3c6089fa173f7a1259135608bb 299 SUPERFAMILY SSF53850 95 296 1.99E-25 T 13-09-2016 THL1_RS04415 f829ba3c6089fa173f7a1259135608bb 299 Gene3D G3DSA:1.10.10.10 8 89 4.6E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS04415 f829ba3c6089fa173f7a1259135608bb 299 Gene3D G3DSA:3.40.190.10 164 258 7.5E-17 T 13-09-2016 THL1_RS04415 f829ba3c6089fa173f7a1259135608bb 299 PANTHER PTHR30537 1 292 1.2E-57 T 13-09-2016 THL1_RS04415 f829ba3c6089fa173f7a1259135608bb 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.0E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS04415 f829ba3c6089fa173f7a1259135608bb 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.0E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS04415 f829ba3c6089fa173f7a1259135608bb 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.0E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS04415 f829ba3c6089fa173f7a1259135608bb 299 Pfam PF03466 LysR substrate binding domain 95 289 9.4E-25 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS04415 f829ba3c6089fa173f7a1259135608bb 299 SUPERFAMILY SSF46785 2 87 4.28E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS06690 417046f417dfe090c38595dbc2d2f099 581 Gene3D G3DSA:3.20.20.450 8 241 3.2E-64 T 13-09-2016 IPR001633 EAL domain THL1_RS06690 417046f417dfe090c38595dbc2d2f099 581 SMART SM00267 389 576 5.5E-7 T 13-09-2016 IPR000160 GGDEF domain THL1_RS06690 417046f417dfe090c38595dbc2d2f099 581 PANTHER PTHR33121 10 277 4.5E-54 T 13-09-2016 THL1_RS06690 417046f417dfe090c38595dbc2d2f099 581 SUPERFAMILY SSF54631 273 396 1.49E-8 T 13-09-2016 THL1_RS06690 417046f417dfe090c38595dbc2d2f099 581 Pfam PF00571 CBS domain 274 315 7.4E-5 T 13-09-2016 IPR000644 CBS domain THL1_RS06690 417046f417dfe090c38595dbc2d2f099 581 Pfam PF00563 EAL domain 9 239 3.5E-56 T 13-09-2016 IPR001633 EAL domain THL1_RS06690 417046f417dfe090c38595dbc2d2f099 581 SMART SM00052 2 246 2.4E-42 T 13-09-2016 IPR001633 EAL domain THL1_RS06690 417046f417dfe090c38595dbc2d2f099 581 Gene3D G3DSA:3.30.70.270 404 569 1.3E-20 T 13-09-2016 THL1_RS06690 417046f417dfe090c38595dbc2d2f099 581 Pfam PF00990 Diguanylate cyclase, GGDEF domain 405 489 2.6E-13 T 13-09-2016 IPR000160 GGDEF domain THL1_RS06690 417046f417dfe090c38595dbc2d2f099 581 Gene3D G3DSA:3.10.580.10 275 394 3.3E-8 T 13-09-2016 THL1_RS06690 417046f417dfe090c38595dbc2d2f099 581 SUPERFAMILY SSF55073 406 572 9.42E-22 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS06690 417046f417dfe090c38595dbc2d2f099 581 PANTHER PTHR33121:SF10 10 277 4.5E-54 T 13-09-2016 THL1_RS06690 417046f417dfe090c38595dbc2d2f099 581 SUPERFAMILY SSF141868 8 242 1.1E-67 T 13-09-2016 IPR001633 EAL domain THL1_RS06690 417046f417dfe090c38595dbc2d2f099 581 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 421 489 2.0E-13 T 13-09-2016 IPR000160 GGDEF domain THL1_RS03355 33ef4a2f69a4c78cf30f12d3ca34aa7d 344 Gene3D G3DSA:3.30.700.10 296 331 3.0E-9 T 13-09-2016 THL1_RS03355 33ef4a2f69a4c78cf30f12d3ca34aa7d 344 PANTHER PTHR34980:SF1 167 324 5.1E-58 T 13-09-2016 THL1_RS03355 33ef4a2f69a4c78cf30f12d3ca34aa7d 344 PANTHER PTHR34980:SF1 2 55 5.1E-58 T 13-09-2016 THL1_RS03355 33ef4a2f69a4c78cf30f12d3ca34aa7d 344 Pfam PF05656 Protein of unknown function (DUF805) 178 283 2.1E-21 T 13-09-2016 IPR008523 Protein of unknown function DUF805 GO:0016021 THL1_RS03355 33ef4a2f69a4c78cf30f12d3ca34aa7d 344 PANTHER PTHR34980 167 324 5.1E-58 T 13-09-2016 THL1_RS03355 33ef4a2f69a4c78cf30f12d3ca34aa7d 344 PANTHER PTHR34980 2 55 5.1E-58 T 13-09-2016 THL1_RS05895 1db6e37a5c68642f9bd40956ea5bfc3b 620 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 3 619 47.646 T 13-09-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 THL1_RS05895 1db6e37a5c68642f9bd40956ea5bfc3b 620 PANTHER PTHR30081:SF1 401 618 1.8E-199 T 13-09-2016 THL1_RS05895 1db6e37a5c68642f9bd40956ea5bfc3b 620 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 342 599 5.9E-67 T 13-09-2016 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THL1_RS05895 1db6e37a5c68642f9bd40956ea5bfc3b 620 Pfam PF07549 SecD/SecF GG Motif 118 140 1.1E-5 T 13-09-2016 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site THL1_RS05895 1db6e37a5c68642f9bd40956ea5bfc3b 620 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 124 606 6.3E-130 T 13-09-2016 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 THL1_RS05895 1db6e37a5c68642f9bd40956ea5bfc3b 620 PANTHER PTHR30081:SF1 310 382 1.8E-199 T 13-09-2016 THL1_RS05895 1db6e37a5c68642f9bd40956ea5bfc3b 620 PANTHER PTHR30081:SF1 227 285 1.8E-199 T 13-09-2016 THL1_RS05895 1db6e37a5c68642f9bd40956ea5bfc3b 620 PANTHER PTHR30081:SF1 1 174 1.8E-199 T 13-09-2016 THL1_RS05895 1db6e37a5c68642f9bd40956ea5bfc3b 620 SUPERFAMILY SSF82866 416 611 1.05E-39 T 13-09-2016 THL1_RS05895 1db6e37a5c68642f9bd40956ea5bfc3b 620 SUPERFAMILY SSF82866 327 346 1.05E-39 T 13-09-2016 THL1_RS05895 1db6e37a5c68642f9bd40956ea5bfc3b 620 Pfam PF13721 SecD export protein N-terminal TM region 2 104 3.4E-33 T 13-09-2016 IPR027398 SecD export protein N-terminal TM domain THL1_RS05895 1db6e37a5c68642f9bd40956ea5bfc3b 620 Gene3D G3DSA:1.20.1640.10 464 612 4.6E-25 T 13-09-2016 THL1_RS05895 1db6e37a5c68642f9bd40956ea5bfc3b 620 PANTHER PTHR30081 401 618 1.8E-199 T 13-09-2016 THL1_RS05895 1db6e37a5c68642f9bd40956ea5bfc3b 620 PANTHER PTHR30081 227 285 1.8E-199 T 13-09-2016 THL1_RS05895 1db6e37a5c68642f9bd40956ea5bfc3b 620 PANTHER PTHR30081 310 382 1.8E-199 T 13-09-2016 THL1_RS05895 1db6e37a5c68642f9bd40956ea5bfc3b 620 PANTHER PTHR30081 1 174 1.8E-199 T 13-09-2016 THL1_RS05895 1db6e37a5c68642f9bd40956ea5bfc3b 620 Pfam PF02355 Protein export membrane protein 443 606 2.0E-17 T 13-09-2016 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial THL1_RS04550 0f3b9c7a2c53ad17fe8055ad580c7436 153 Gene3D G3DSA:3.30.450.20 14 129 6.6E-17 T 13-09-2016 THL1_RS04550 0f3b9c7a2c53ad17fe8055ad580c7436 153 SUPERFAMILY SSF55785 12 128 3.7E-15 T 13-09-2016 IPR000014 PAS domain THL1_RS04550 0f3b9c7a2c53ad17fe8055ad580c7436 153 SMART SM00091 11 77 5.1E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS04550 0f3b9c7a2c53ad17fe8055ad580c7436 153 Pfam PF08448 PAS fold 21 139 1.8E-12 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS04550 0f3b9c7a2c53ad17fe8055ad580c7436 153 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 82 3.3E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS02565 6e8cd5ee03f161d2d6d7155579ad54d1 410 PIRSF PIRSF000813 1 407 4.0E-194 T 13-09-2016 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 THL1_RS02565 6e8cd5ee03f161d2d6d7155579ad54d1 410 Pfam PF01966 HD domain 231 310 4.6E-8 T 13-09-2016 IPR006674 HD domain THL1_RS02565 6e8cd5ee03f161d2d6d7155579ad54d1 410 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 149 212 2.0E-12 T 13-09-2016 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain THL1_RS02565 6e8cd5ee03f161d2d6d7155579ad54d1 410 PANTHER PTHR13734 1 237 1.3E-69 T 13-09-2016 THL1_RS02565 6e8cd5ee03f161d2d6d7155579ad54d1 410 SUPERFAMILY SSF81891 120 400 4.58E-50 T 13-09-2016 THL1_RS02565 6e8cd5ee03f161d2d6d7155579ad54d1 410 SUPERFAMILY SSF81301 1 119 4.47E-28 T 13-09-2016 THL1_RS02565 6e8cd5ee03f161d2d6d7155579ad54d1 410 Hamap MF_01262 CCA-adding enzyme [cca]. 1 401 40.838 T 13-09-2016 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 THL1_RS02565 6e8cd5ee03f161d2d6d7155579ad54d1 410 Gene3D G3DSA:1.10.3090.10 122 360 3.5E-50 T 13-09-2016 THL1_RS02565 6e8cd5ee03f161d2d6d7155579ad54d1 410 Hamap MF_01261 Multifunctional CCA protein [cca]. 1 407 54.193 T 13-09-2016 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 THL1_RS02565 6e8cd5ee03f161d2d6d7155579ad54d1 410 Pfam PF01743 Poly A polymerase head domain 4 122 1.4E-15 T 13-09-2016 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 THL1_RS02565 6e8cd5ee03f161d2d6d7155579ad54d1 410 Gene3D G3DSA:3.30.460.10 1 121 1.9E-27 T 13-09-2016 THL1_RS19955 5becb5671cc5c1f1e5d96f65bd8d79a7 326 SUPERFAMILY SSF52317 4 197 1.28E-35 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS19955 5becb5671cc5c1f1e5d96f65bd8d79a7 326 SUPERFAMILY SSF46689 268 318 9.41E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19955 5becb5671cc5c1f1e5d96f65bd8d79a7 326 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 269 311 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS19955 5becb5671cc5c1f1e5d96f65bd8d79a7 326 Gene3D G3DSA:3.40.50.880 6 221 1.3E-47 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS19955 5becb5671cc5c1f1e5d96f65bd8d79a7 326 SMART SM00342 232 315 2.2E-26 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS19955 5becb5671cc5c1f1e5d96f65bd8d79a7 326 PANTHER PTHR11019:SF68 96 323 1.1E-62 T 13-09-2016 THL1_RS19955 5becb5671cc5c1f1e5d96f65bd8d79a7 326 SUPERFAMILY SSF46689 215 266 1.25E-6 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19955 5becb5671cc5c1f1e5d96f65bd8d79a7 326 Gene3D G3DSA:1.10.10.60 222 268 4.9E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19955 5becb5671cc5c1f1e5d96f65bd8d79a7 326 Pfam PF01965 DJ-1/PfpI family 92 177 5.3E-12 T 13-09-2016 IPR002818 DJ-1/PfpI THL1_RS19955 5becb5671cc5c1f1e5d96f65bd8d79a7 326 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 299 315 3.3E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS19955 5becb5671cc5c1f1e5d96f65bd8d79a7 326 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 284 299 3.3E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS19955 5becb5671cc5c1f1e5d96f65bd8d79a7 326 Pfam PF12833 Helix-turn-helix domain 238 317 1.2E-23 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS19955 5becb5671cc5c1f1e5d96f65bd8d79a7 326 PANTHER PTHR11019 96 323 1.1E-62 T 13-09-2016 THL1_RS19955 5becb5671cc5c1f1e5d96f65bd8d79a7 326 Gene3D G3DSA:1.10.10.60 269 318 2.8E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS03390 3b3afca69a28bb25ff39033389f4faab 399 Pfam PF00579 tRNA synthetases class I (W and Y) 31 311 5.8E-81 T 13-09-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS03390 3b3afca69a28bb25ff39033389f4faab 399 Gene3D G3DSA:3.10.290.10 327 395 8.5E-16 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS03390 3b3afca69a28bb25ff39033389f4faab 399 SUPERFAMILY SSF52374 4 310 2.78E-99 T 13-09-2016 THL1_RS03390 3b3afca69a28bb25ff39033389f4faab 399 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 13-09-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS03390 3b3afca69a28bb25ff39033389f4faab 399 Gene3D G3DSA:1.10.240.10 228 326 2.3E-33 T 13-09-2016 THL1_RS03390 3b3afca69a28bb25ff39033389f4faab 399 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 2 396 47.77 T 13-09-2016 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 THL1_RS03390 3b3afca69a28bb25ff39033389f4faab 399 PANTHER PTHR11766 4 397 3.1E-222 T 13-09-2016 IPR024088 Tyrosine-tRNA ligase, bacterial-type GO:0004831 KEGG: 00970+6.1.1.1 THL1_RS03390 3b3afca69a28bb25ff39033389f4faab 399 Pfam PF01479 S4 domain 336 379 2.1E-5 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS03390 3b3afca69a28bb25ff39033389f4faab 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 46 68 7.3E-26 T 13-09-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 THL1_RS03390 3b3afca69a28bb25ff39033389f4faab 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 178 200 7.3E-26 T 13-09-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 THL1_RS03390 3b3afca69a28bb25ff39033389f4faab 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 211 223 7.3E-26 T 13-09-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 THL1_RS03390 3b3afca69a28bb25ff39033389f4faab 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 7.3E-26 T 13-09-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 THL1_RS03390 3b3afca69a28bb25ff39033389f4faab 399 SUPERFAMILY SSF55174 320 395 2.22E-13 T 13-09-2016 THL1_RS03390 3b3afca69a28bb25ff39033389f4faab 399 PANTHER PTHR11766:SF1 4 397 3.1E-222 T 13-09-2016 THL1_RS03390 3b3afca69a28bb25ff39033389f4faab 399 Gene3D G3DSA:3.40.50.620 10 227 4.0E-87 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS03390 3b3afca69a28bb25ff39033389f4faab 399 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 395 3.2E-121 T 13-09-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 THL1_RS04460 0f9232b5807ef025d00ee054206bf645 363 SUPERFAMILY SSF56219 44 62 9.95E-32 T 13-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase THL1_RS04460 0f9232b5807ef025d00ee054206bf645 363 SUPERFAMILY SSF56219 94 360 9.95E-32 T 13-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase THL1_RS04460 0f9232b5807ef025d00ee054206bf645 363 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 58 350 3.3E-17 T 13-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase THL1_RS04460 0f9232b5807ef025d00ee054206bf645 363 PANTHER PTHR14859 79 362 1.6E-18 T 13-09-2016 IPR027317 PGAP2-interacting protein THL1_RS04460 0f9232b5807ef025d00ee054206bf645 363 PANTHER PTHR14859:SF0 79 362 1.6E-18 T 13-09-2016 THL1_RS04460 0f9232b5807ef025d00ee054206bf645 363 Gene3D G3DSA:3.60.10.10 46 357 2.6E-14 T 13-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase THL1_RS20140 a02d84094853d0c11566b6934d593851 286 PANTHER PTHR30126 1 286 4.3E-132 T 13-09-2016 THL1_RS20140 a02d84094853d0c11566b6934d593851 286 PANTHER PTHR30126:SF21 1 286 4.3E-132 T 13-09-2016 THL1_RS20140 a02d84094853d0c11566b6934d593851 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.4E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS20140 a02d84094853d0c11566b6934d593851 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.4E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS20140 a02d84094853d0c11566b6934d593851 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.4E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS20140 a02d84094853d0c11566b6934d593851 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.2E-19 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS20140 a02d84094853d0c11566b6934d593851 286 Pfam PF03466 LysR substrate binding domain 87 272 6.0E-17 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS20140 a02d84094853d0c11566b6934d593851 286 SUPERFAMILY SSF46785 1 105 4.33E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20140 a02d84094853d0c11566b6934d593851 286 Gene3D G3DSA:3.40.190.10 85 193 1.8E-10 T 13-09-2016 THL1_RS20140 a02d84094853d0c11566b6934d593851 286 Gene3D G3DSA:1.10.10.10 1 82 6.5E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20140 a02d84094853d0c11566b6934d593851 286 SUPERFAMILY SSF53850 86 273 1.74E-21 T 13-09-2016 THL1_RS14385 4d23581af32da26519c70811c485ef02 319 SMART SM00342 228 314 3.1E-21 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS14385 4d23581af32da26519c70811c485ef02 319 PANTHER PTHR11019 47 317 1.6E-51 T 13-09-2016 THL1_RS14385 4d23581af32da26519c70811c485ef02 319 Pfam PF14525 AraC-binding-like domain 25 192 1.4E-24 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS14385 4d23581af32da26519c70811c485ef02 319 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 265 310 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS14385 4d23581af32da26519c70811c485ef02 319 Gene3D G3DSA:2.60.120.280 76 184 2.3E-4 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS14385 4d23581af32da26519c70811c485ef02 319 Gene3D G3DSA:1.10.10.60 265 312 5.8E-4 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS14385 4d23581af32da26519c70811c485ef02 319 Gene3D G3DSA:1.10.10.60 211 264 4.2E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS14385 4d23581af32da26519c70811c485ef02 319 Pfam PF12833 Helix-turn-helix domain 234 316 8.3E-25 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS14385 4d23581af32da26519c70811c485ef02 319 PANTHER PTHR11019:SF54 47 317 1.6E-51 T 13-09-2016 THL1_RS14385 4d23581af32da26519c70811c485ef02 319 SUPERFAMILY SSF51215 75 152 1.09E-5 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS14385 4d23581af32da26519c70811c485ef02 319 SUPERFAMILY SSF46689 214 263 4.44E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS12875 fcda5583531e555c7835fa41e344e6d7 229 SUPERFAMILY SSF53474 126 225 6.03E-29 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS12875 fcda5583531e555c7835fa41e344e6d7 229 SUPERFAMILY SSF53474 3 96 6.03E-29 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS12875 fcda5583531e555c7835fa41e344e6d7 229 PANTHER PTHR10992:SF832 3 228 7.3E-36 T 13-09-2016 THL1_RS12875 fcda5583531e555c7835fa41e344e6d7 229 Pfam PF12697 Alpha/beta hydrolase family 7 220 8.6E-18 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS12875 fcda5583531e555c7835fa41e344e6d7 229 PANTHER PTHR10992 3 228 7.3E-36 T 13-09-2016 THL1_RS12875 fcda5583531e555c7835fa41e344e6d7 229 Gene3D G3DSA:3.40.50.1820 5 227 4.1E-34 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS10170 360f0d8bb08f163c21b41417502b0673 237 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 25 3.5E-6 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS10170 360f0d8bb08f163c21b41417502b0673 237 PANTHER PTHR39583:SF1 1 234 8.2E-43 T 13-09-2016 THL1_RS10170 360f0d8bb08f163c21b41417502b0673 237 Pfam PF11612 Type II secretion system (T2SS), protein J 57 197 6.1E-43 T 13-09-2016 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 THL1_RS10170 360f0d8bb08f163c21b41417502b0673 237 PANTHER PTHR39583 1 234 8.2E-43 T 13-09-2016 THL1_RS10170 360f0d8bb08f163c21b41417502b0673 237 Gene3D G3DSA:2.10.70.20 146 197 1.2E-7 T 13-09-2016 THL1_RS10170 360f0d8bb08f163c21b41417502b0673 237 Gene3D G3DSA:3.10.610.10 36 143 2.6E-30 T 13-09-2016 THL1_RS10170 360f0d8bb08f163c21b41417502b0673 237 Pfam PF13633 Prokaryotic N-terminal methylation site 5 30 2.9E-9 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS10170 360f0d8bb08f163c21b41417502b0673 237 SUPERFAMILY SSF54523 38 202 7.85E-42 T 13-09-2016 THL1_RS10170 360f0d8bb08f163c21b41417502b0673 237 TIGRFAM TIGR01711 gspJ: type II secretion system protein J 5 200 1.4E-65 T 13-09-2016 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 THL1_RS27935 90f1c7970b8d95770ba71a8ce988e058 312 PANTHER PTHR30346 1 296 8.8E-112 T 13-09-2016 THL1_RS27935 90f1c7970b8d95770ba71a8ce988e058 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.3E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS27935 90f1c7970b8d95770ba71a8ce988e058 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.3E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS27935 90f1c7970b8d95770ba71a8ce988e058 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.3E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS27935 90f1c7970b8d95770ba71a8ce988e058 312 SUPERFAMILY SSF53850 88 296 2.58E-37 T 13-09-2016 THL1_RS27935 90f1c7970b8d95770ba71a8ce988e058 312 Gene3D G3DSA:3.40.190.10 175 273 1.8E-29 T 13-09-2016 THL1_RS27935 90f1c7970b8d95770ba71a8ce988e058 312 Pfam PF03466 LysR substrate binding domain 88 296 8.2E-45 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS27935 90f1c7970b8d95770ba71a8ce988e058 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.4E-17 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS27935 90f1c7970b8d95770ba71a8ce988e058 312 SUPERFAMILY SSF46785 1 85 6.08E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS27935 90f1c7970b8d95770ba71a8ce988e058 312 Gene3D G3DSA:1.10.10.10 1 84 3.2E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS27935 90f1c7970b8d95770ba71a8ce988e058 312 PANTHER PTHR30346:SF15 1 296 8.8E-112 T 13-09-2016 THL1_RS27935 90f1c7970b8d95770ba71a8ce988e058 312 Gene3D G3DSA:3.40.190.10 93 174 2.9E-14 T 13-09-2016 THL1_RS20775 cc1233ed9f14816636a77c4b26ca603d 295 SMART SM00849 19 209 5.9E-25 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS20775 cc1233ed9f14816636a77c4b26ca603d 295 SUPERFAMILY SSF56281 17 292 1.68E-49 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS20775 cc1233ed9f14816636a77c4b26ca603d 295 PANTHER PTHR11935 13 276 1.5E-102 T 13-09-2016 THL1_RS20775 cc1233ed9f14816636a77c4b26ca603d 295 Pfam PF00753 Metallo-beta-lactamase superfamily 18 209 1.9E-27 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS20775 cc1233ed9f14816636a77c4b26ca603d 295 Gene3D G3DSA:3.60.15.10 10 251 1.4E-47 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS20775 cc1233ed9f14816636a77c4b26ca603d 295 PANTHER PTHR11935:SF110 13 276 1.5E-102 T 13-09-2016 THL1_RS20850 fc5f0345821937462819e99b7795dd4a 482 PANTHER PTHR11699:SF216 20 481 7.6E-184 T 13-09-2016 THL1_RS20850 fc5f0345821937462819e99b7795dd4a 482 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 255 266 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS20850 fc5f0345821937462819e99b7795dd4a 482 PANTHER PTHR11699 20 481 7.6E-184 T 13-09-2016 THL1_RS20850 fc5f0345821937462819e99b7795dd4a 482 Gene3D G3DSA:3.40.605.10 19 241 1.7E-53 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS20850 fc5f0345821937462819e99b7795dd4a 482 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 227 234 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS20850 fc5f0345821937462819e99b7795dd4a 482 Gene3D G3DSA:3.40.309.10 242 429 6.9E-64 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS20850 fc5f0345821937462819e99b7795dd4a 482 SUPERFAMILY SSF53720 19 453 1.96E-124 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS20850 fc5f0345821937462819e99b7795dd4a 482 PIRSF PIRSF036492 10 482 3.8E-168 T 13-09-2016 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 THL1_RS20850 fc5f0345821937462819e99b7795dd4a 482 Pfam PF00171 Aldehyde dehydrogenase family 19 451 1.3E-95 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS20795 944f3c466d35827457725e8f6e98465f 345 Gene3D G3DSA:2.130.10.10 45 315 1.4E-29 T 13-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THL1_RS20795 944f3c466d35827457725e8f6e98465f 345 SUPERFAMILY SSF50939 37 313 1.63E-37 T 13-09-2016 IPR011040 Sialidases THL1_RS20795 944f3c466d35827457725e8f6e98465f 345 Pfam PF14870 Photosynthesis system II assembly factor YCF48 145 214 1.0E-9 T 13-09-2016 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain THL1_RS20795 944f3c466d35827457725e8f6e98465f 345 Pfam PF14870 Photosynthesis system II assembly factor YCF48 51 110 8.5E-7 T 13-09-2016 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain THL1_RS13475 365adef4ddb23ede6e35afa21ef40441 313 Gene3D G3DSA:3.40.190.10 99 188 3.4E-13 T 13-09-2016 THL1_RS13475 365adef4ddb23ede6e35afa21ef40441 313 SUPERFAMILY SSF53850 99 309 3.58E-37 T 13-09-2016 THL1_RS13475 365adef4ddb23ede6e35afa21ef40441 313 Gene3D G3DSA:3.40.190.10 189 274 5.8E-16 T 13-09-2016 THL1_RS13475 365adef4ddb23ede6e35afa21ef40441 313 Pfam PF03466 LysR substrate binding domain 98 305 7.2E-35 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS13475 365adef4ddb23ede6e35afa21ef40441 313 Gene3D G3DSA:1.10.10.10 12 93 5.7E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13475 365adef4ddb23ede6e35afa21ef40441 313 PANTHER PTHR30126:SF3 11 306 2.6E-56 T 13-09-2016 THL1_RS13475 365adef4ddb23ede6e35afa21ef40441 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 73 1.6E-14 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS13475 365adef4ddb23ede6e35afa21ef40441 313 PANTHER PTHR30126 11 306 2.6E-56 T 13-09-2016 THL1_RS13475 365adef4ddb23ede6e35afa21ef40441 313 SUPERFAMILY SSF46785 11 113 8.16E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07940 f945b70927e7a558168d3db60070d163 302 SUPERFAMILY SSF53697 121 280 3.24E-21 T 13-09-2016 THL1_RS07940 f945b70927e7a558168d3db60070d163 302 PANTHER PTHR30514 30 282 1.4E-31 T 13-09-2016 THL1_RS07940 f945b70927e7a558168d3db60070d163 302 SUPERFAMILY SSF46689 30 95 3.94E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS07940 f945b70927e7a558168d3db60070d163 302 PANTHER PTHR30514:SF3 30 282 1.4E-31 T 13-09-2016 THL1_RS07940 f945b70927e7a558168d3db60070d163 302 Pfam PF01380 SIS domain 148 254 9.0E-13 T 13-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 THL1_RS07940 f945b70927e7a558168d3db60070d163 302 Gene3D G3DSA:1.10.10.10 30 94 4.2E-16 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07940 f945b70927e7a558168d3db60070d163 302 Pfam PF01418 Helix-turn-helix domain, rpiR family 30 84 1.4E-9 T 13-09-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 THL1_RS07940 f945b70927e7a558168d3db60070d163 302 Gene3D G3DSA:3.40.50.10490 129 282 9.9E-21 T 13-09-2016 THL1_RS01725 98d0f79f4bbfe0bfe9cc88a95d3347ef 197 SUPERFAMILY SSF46689 5 78 6.16E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01725 98d0f79f4bbfe0bfe9cc88a95d3347ef 197 PANTHER PTHR30055 1 195 3.7E-110 T 13-09-2016 THL1_RS01725 98d0f79f4bbfe0bfe9cc88a95d3347ef 197 SUPERFAMILY SSF48498 82 193 8.9E-21 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS01725 98d0f79f4bbfe0bfe9cc88a95d3347ef 197 TIGRFAM TIGR03384 betaine_BetI: transcriptional repressor BetI 2 192 1.7E-72 T 13-09-2016 IPR017757 Transcriptional repressor BetI UniPathway: UPA00529 THL1_RS01725 98d0f79f4bbfe0bfe9cc88a95d3347ef 197 PANTHER PTHR30055:SF61 1 195 3.7E-110 T 13-09-2016 THL1_RS01725 98d0f79f4bbfe0bfe9cc88a95d3347ef 197 Hamap MF_00768 HTH-type transcriptional regulator BetI [betI]. 1 197 103.08 T 13-09-2016 IPR017757 Transcriptional repressor BetI UniPathway: UPA00529 THL1_RS01725 98d0f79f4bbfe0bfe9cc88a95d3347ef 197 Gene3D G3DSA:1.10.357.10 1 193 7.8E-43 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS01725 98d0f79f4bbfe0bfe9cc88a95d3347ef 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 13-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site THL1_RS01725 98d0f79f4bbfe0bfe9cc88a95d3347ef 197 Pfam PF13977 Bacterial transcriptional repressor 87 193 2.3E-32 T 13-09-2016 THL1_RS01725 98d0f79f4bbfe0bfe9cc88a95d3347ef 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 1.9E-9 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS02075 6c5abd9ac81846af3a292b74bf518e01 412 SMART SM00471 159 295 1.9E-12 T 13-09-2016 IPR003607 HD/PDEase domain THL1_RS02075 6c5abd9ac81846af3a292b74bf518e01 412 Pfam PF01966 HD domain 164 285 2.5E-16 T 13-09-2016 IPR006674 HD domain THL1_RS02075 6c5abd9ac81846af3a292b74bf518e01 412 Pfam PF11871 Domain of unknown function (DUF3391) 2 132 2.3E-36 T 13-09-2016 IPR021812 Protein of unknown function DUF3391 THL1_RS02075 6c5abd9ac81846af3a292b74bf518e01 412 Gene3D G3DSA:1.10.3210.10 150 309 1.1E-27 T 13-09-2016 IPR006674 HD domain THL1_RS02075 6c5abd9ac81846af3a292b74bf518e01 412 SUPERFAMILY SSF109604 157 324 2.93E-35 T 13-09-2016 THL1_RS02075 6c5abd9ac81846af3a292b74bf518e01 412 TIGRFAM TIGR00277 HDIG: HDIG domain 161 254 1.3E-10 T 13-09-2016 IPR006675 HDIG domain THL1_RS00135 d0634db2dddb58c96a637c2115a710b3 275 Gene3D G3DSA:3.40.192.10 2 107 4.7E-34 T 13-09-2016 THL1_RS00135 d0634db2dddb58c96a637c2115a710b3 275 PANTHER PTHR21089 1 274 2.6E-140 T 13-09-2016 THL1_RS00135 d0634db2dddb58c96a637c2115a710b3 275 SUPERFAMILY SSF53223 2 101 2.65E-28 T 13-09-2016 THL1_RS00135 d0634db2dddb58c96a637c2115a710b3 275 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 118 191 1.8E-8 T 13-09-2016 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase THL1_RS00135 d0634db2dddb58c96a637c2115a710b3 275 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 2 271 31.426 T 13-09-2016 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS00135 d0634db2dddb58c96a637c2115a710b3 275 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 5 272 1.6E-77 T 13-09-2016 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS00135 d0634db2dddb58c96a637c2115a710b3 275 Gene3D G3DSA:3.40.50.720 108 246 3.5E-45 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS00135 d0634db2dddb58c96a637c2115a710b3 275 SUPERFAMILY SSF51735 102 271 7.91E-41 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS00135 d0634db2dddb58c96a637c2115a710b3 275 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 7 88 4.0E-22 T 13-09-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS00135 d0634db2dddb58c96a637c2115a710b3 275 PANTHER PTHR21089:SF2 1 274 2.6E-140 T 13-09-2016 THL1_RS23280 418cb2a528ea518b59424155ee2456ee 403 Gene3D G3DSA:3.30.70.360 185 301 8.5E-39 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS23280 418cb2a528ea518b59424155ee2456ee 403 SUPERFAMILY SSF55031 188 300 4.71E-30 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS23280 418cb2a528ea518b59424155ee2456ee 403 Pfam PF01546 Peptidase family M20/M25/M40 77 385 8.6E-33 T 13-09-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 THL1_RS23280 418cb2a528ea518b59424155ee2456ee 403 PANTHER PTHR11014:SF63 7 393 6.5E-154 T 13-09-2016 THL1_RS23280 418cb2a528ea518b59424155ee2456ee 403 Gene3D G3DSA:3.40.630.10 4 182 1.0E-100 T 13-09-2016 THL1_RS23280 418cb2a528ea518b59424155ee2456ee 403 Gene3D G3DSA:3.40.630.10 302 394 1.0E-100 T 13-09-2016 THL1_RS23280 418cb2a528ea518b59424155ee2456ee 403 SUPERFAMILY SSF53187 6 201 7.61E-88 T 13-09-2016 THL1_RS23280 418cb2a528ea518b59424155ee2456ee 403 SUPERFAMILY SSF53187 302 390 7.61E-88 T 13-09-2016 THL1_RS23280 418cb2a528ea518b59424155ee2456ee 403 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 21 375 1.7E-106 T 13-09-2016 IPR017439 Amidohydrolase GO:0016787 THL1_RS23280 418cb2a528ea518b59424155ee2456ee 403 Pfam PF07687 Peptidase dimerisation domain 191 287 2.6E-9 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS23280 418cb2a528ea518b59424155ee2456ee 403 PANTHER PTHR11014 7 393 6.5E-154 T 13-09-2016 THL1_RS23280 418cb2a528ea518b59424155ee2456ee 403 PIRSF PIRSF005962 5 393 3.4E-123 T 13-09-2016 IPR017439 Amidohydrolase GO:0016787 THL1_RS21690 92edc67fdcc357ebeba5e7f380f389c4 125 Gene3D G3DSA:2.40.50.100 3 123 3.7E-44 T 13-09-2016 THL1_RS21690 92edc67fdcc357ebeba5e7f380f389c4 125 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 1 122 27.912 T 13-09-2016 IPR002930 Glycine cleavage system H-protein THL1_RS21690 92edc67fdcc357ebeba5e7f380f389c4 125 PANTHER PTHR11715 2 125 1.5E-58 T 13-09-2016 IPR002930 Glycine cleavage system H-protein THL1_RS21690 92edc67fdcc357ebeba5e7f380f389c4 125 Pfam PF01597 Glycine cleavage H-protein 4 123 7.0E-41 T 13-09-2016 IPR002930 Glycine cleavage system H-protein THL1_RS21690 92edc67fdcc357ebeba5e7f380f389c4 125 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 123 8.5E-42 T 13-09-2016 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 THL1_RS21690 92edc67fdcc357ebeba5e7f380f389c4 125 SUPERFAMILY SSF51230 2 122 8.9E-38 T 13-09-2016 IPR011053 Single hybrid motif THL1_RS24325 99c6925169a774b6e70071a89c925c17 645 Gene3D G3DSA:3.40.50.980 78 263 8.2E-45 T 13-09-2016 THL1_RS24325 99c6925169a774b6e70071a89c925c17 645 Gene3D G3DSA:3.30.300.30 515 636 3.5E-26 T 13-09-2016 THL1_RS24325 99c6925169a774b6e70071a89c925c17 645 Gene3D G3DSA:3.40.50.980 264 421 4.0E-28 T 13-09-2016 THL1_RS24325 99c6925169a774b6e70071a89c925c17 645 Pfam PF00501 AMP-binding enzyme 83 519 6.0E-89 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS24325 99c6925169a774b6e70071a89c925c17 645 Gene3D G3DSA:2.30.38.10 436 512 3.5E-6 T 13-09-2016 THL1_RS24325 99c6925169a774b6e70071a89c925c17 645 PANTHER PTHR24095:SF178 3 642 0.0 T 13-09-2016 THL1_RS24325 99c6925169a774b6e70071a89c925c17 645 PANTHER PTHR24095 3 642 0.0 T 13-09-2016 THL1_RS24325 99c6925169a774b6e70071a89c925c17 645 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 2 642 53.819 T 13-09-2016 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: REACT_13433 THL1_RS24325 99c6925169a774b6e70071a89c925c17 645 SUPERFAMILY SSF56801 11 638 5.36E-186 T 13-09-2016 THL1_RS24325 99c6925169a774b6e70071a89c925c17 645 ProSitePatterns PS00455 Putative AMP-binding domain signature. 258 269 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS24325 99c6925169a774b6e70071a89c925c17 645 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 24 80 1.4E-21 T 13-09-2016 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 THL1_RS24325 99c6925169a774b6e70071a89c925c17 645 Pfam PF13193 AMP-binding enzyme C-terminal domain 528 606 9.7E-23 T 13-09-2016 IPR025110 AMP-binding enzyme C-terminal domain THL1_RS24325 99c6925169a774b6e70071a89c925c17 645 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 20 640 0.0 T 13-09-2016 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: REACT_13433 THL1_RS07470 9604449c7d161d86fa816f703d4798da 113 PANTHER PTHR30561:SF0 4 107 1.6E-35 T 13-09-2016 THL1_RS07470 9604449c7d161d86fa816f703d4798da 113 SUPERFAMILY SSF103481 9 108 2.62E-19 T 13-09-2016 THL1_RS07470 9604449c7d161d86fa816f703d4798da 113 Pfam PF00893 Small Multidrug Resistance protein 6 97 1.6E-22 T 13-09-2016 IPR000390 Small multidrug resistance protein family GO:0016021 THL1_RS07470 9604449c7d161d86fa816f703d4798da 113 PANTHER PTHR30561 4 107 1.6E-35 T 13-09-2016 THL1_RS15230 53132abf149575a28346e00529d24a56 271 Gene3D G3DSA:3.40.50.300 3 87 3.4E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15230 53132abf149575a28346e00529d24a56 271 Pfam PF05707 Zonular occludens toxin (Zot) 4 85 3.3E-12 T 13-09-2016 IPR008900 Zona occludens toxin THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 Pfam PF00773 RNB domain 264 596 1.2E-110 T 13-09-2016 THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 SUPERFAMILY SSF50249 71 151 3.0E-16 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 Pfam PF08461 Ribonuclease R winged-helix domain 27 81 2.3E-8 T 13-09-2016 IPR013668 Ribonuclease R winged-helix domain THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 78 741 2.2E-228 T 13-09-2016 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 Pfam PF08206 Ribonuclease B OB domain 91 148 3.8E-21 T 13-09-2016 IPR013223 Ribonuclease B, N-terminal OB domain THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 PANTHER PTHR23355:SF9 6 775 2.3E-276 T 13-09-2016 THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 SMART SM00955 264 598 1.7E-186 T 13-09-2016 THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 Pfam PF00575 S1 RNA binding domain 658 741 8.3E-12 T 13-09-2016 IPR003029 S1 domain GO:0003676 THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 Gene3D G3DSA:2.40.50.140 661 741 2.5E-18 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 SMART SM00316 659 742 1.9E-12 T 13-09-2016 IPR022967 RNA-binding domain, S1 THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 SUPERFAMILY SSF50249 142 241 1.81E-17 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 SUPERFAMILY SSF50249 224 659 4.45E-148 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 PANTHER PTHR23355 6 775 2.3E-276 T 13-09-2016 THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 SMART SM00357 90 150 2.5E-9 T 13-09-2016 IPR011129 Cold shock protein GO:0003676 THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 SUPERFAMILY SSF50249 661 740 1.12E-20 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 ProSitePatterns PS01175 Ribonuclease II family signature. 565 589 - T 13-09-2016 IPR022966 Ribonuclease II/R, conserved site THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 Hamap MF_01895 Ribonuclease R [rnr]. 42 742 57.646 T 13-09-2016 IPR011805 Ribonuclease R GO:0003723|GO:0004518 THL1_RS25810 e668f7082a6c6548c47207bfe4dc36bf 916 TIGRFAM TIGR02063 RNase_R: ribonuclease R 23 742 4.6E-265 T 13-09-2016 IPR011805 Ribonuclease R GO:0003723|GO:0004518 THL1_RS02010 8cbd6b7c19bd45e365c72b57b3083ac5 417 PANTHER PTHR31817:SF4 209 417 8.5E-14 T 13-09-2016 THL1_RS02010 8cbd6b7c19bd45e365c72b57b3083ac5 417 Pfam PF08014 Domain of unknown function (DUF1704) 35 398 1.1E-111 T 13-09-2016 IPR012548 Protein of unknown function DUF1704 THL1_RS02010 8cbd6b7c19bd45e365c72b57b3083ac5 417 SMART SM01154 33 402 6.6E-103 T 13-09-2016 IPR012548 Protein of unknown function DUF1704 THL1_RS02010 8cbd6b7c19bd45e365c72b57b3083ac5 417 PANTHER PTHR31817 209 417 8.5E-14 T 13-09-2016 THL1_RS01590 c046ba59de81fed9af3ec94dde0081a1 652 Hamap MF_00968 ATP-dependent RNA helicase RhlE [rhlE]. 1 590 49.32 T 13-09-2016 IPR028622 ATP-dependent RNA helicase RhlE GO:0004004|GO:0042255 THL1_RS01590 c046ba59de81fed9af3ec94dde0081a1 652 Pfam PF00271 Helicase conserved C-terminal domain 240 344 1.8E-25 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS01590 c046ba59de81fed9af3ec94dde0081a1 652 SMART SM00490 263 344 5.4E-31 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS01590 c046ba59de81fed9af3ec94dde0081a1 652 SUPERFAMILY SSF52540 24 105 3.72E-6 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01590 c046ba59de81fed9af3ec94dde0081a1 652 Gene3D G3DSA:3.40.50.300 1 216 1.2E-76 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01590 c046ba59de81fed9af3ec94dde0081a1 652 Gene3D G3DSA:3.40.50.300 217 375 3.4E-52 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01590 c046ba59de81fed9af3ec94dde0081a1 652 SUPERFAMILY SSF52540 80 365 3.32E-72 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01590 c046ba59de81fed9af3ec94dde0081a1 652 SMART SM00487 20 227 5.4E-62 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS01590 c046ba59de81fed9af3ec94dde0081a1 652 PANTHER PTHR24031:SF0 431 580 4.4E-214 T 13-09-2016 THL1_RS01590 c046ba59de81fed9af3ec94dde0081a1 652 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 158 166 - T 13-09-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site THL1_RS01590 c046ba59de81fed9af3ec94dde0081a1 652 PANTHER PTHR24031:SF0 1 413 4.4E-214 T 13-09-2016 THL1_RS01590 c046ba59de81fed9af3ec94dde0081a1 652 Pfam PF00270 DEAD/DEAH box helicase 25 199 6.9E-46 T 13-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THL1_RS01590 c046ba59de81fed9af3ec94dde0081a1 652 PANTHER PTHR24031 431 580 4.4E-214 T 13-09-2016 THL1_RS01590 c046ba59de81fed9af3ec94dde0081a1 652 PANTHER PTHR24031 1 413 4.4E-214 T 13-09-2016 THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 Pfam PF00106 short chain dehydrogenase 5 189 4.0E-47 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 PANTHER PTHR24322:SF392 7 136 3.5E-78 T 13-09-2016 THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 183 5.2E-4 T 13-09-2016 THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.6E-5 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 2.6E-5 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 2.6E-5 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 SUPERFAMILY SSF51735 4 234 1.44E-58 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 Gene3D G3DSA:3.40.50.720 4 235 3.5E-61 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 PANTHER PTHR24322 7 136 3.5E-78 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 PANTHER PTHR24322 152 184 3.5E-78 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 PANTHER PTHR24322:SF392 152 184 3.5E-78 T 13-09-2016 THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.7E-19 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.7E-19 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.7E-19 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.7E-19 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.7E-19 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25660 3238aa21426a262c3a465a7bf5677003 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 1.7E-19 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12680 73a59a49837ebb6bf8be8d009c4c63f3 106 SUPERFAMILY SSF54909 1 106 1.02E-34 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS12680 73a59a49837ebb6bf8be8d009c4c63f3 106 PANTHER PTHR21017 3 106 5.7E-26 T 13-09-2016 THL1_RS12680 73a59a49837ebb6bf8be8d009c4c63f3 106 Gene3D G3DSA:3.30.70.900 2 106 1.4E-32 T 13-09-2016 THL1_RS12680 73a59a49837ebb6bf8be8d009c4c63f3 106 Pfam PF07978 NIPSNAP 3 104 4.0E-34 T 13-09-2016 IPR012577 NIPSNAP THL1_RS25065 d82491c067a5bca2d40de847c67e8a1e 304 SUPERFAMILY SSF53850 89 299 3.08E-42 T 13-09-2016 THL1_RS25065 d82491c067a5bca2d40de847c67e8a1e 304 PANTHER PTHR30537:SF21 1 294 7.8E-155 T 13-09-2016 THL1_RS25065 d82491c067a5bca2d40de847c67e8a1e 304 SUPERFAMILY SSF46785 2 112 4.25E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS25065 d82491c067a5bca2d40de847c67e8a1e 304 PANTHER PTHR30537 1 294 7.8E-155 T 13-09-2016 THL1_RS25065 d82491c067a5bca2d40de847c67e8a1e 304 Pfam PF03466 LysR substrate binding domain 88 295 3.9E-42 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS25065 d82491c067a5bca2d40de847c67e8a1e 304 Gene3D G3DSA:1.10.10.10 2 85 2.7E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS25065 d82491c067a5bca2d40de847c67e8a1e 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.2E-20 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS25065 d82491c067a5bca2d40de847c67e8a1e 304 Gene3D G3DSA:3.40.190.10 92 193 4.7E-27 T 13-09-2016 THL1_RS23615 f9cf127de1aa859cfa0d5396d4a96055 97 Pfam PF06844 Protein of unknown function (DUF1244) 27 93 2.8E-37 T 13-09-2016 IPR023163 SMc04008-like domain THL1_RS23615 f9cf127de1aa859cfa0d5396d4a96055 97 SUPERFAMILY SSF158757 1 77 3.53E-37 T 13-09-2016 IPR023163 SMc04008-like domain THL1_RS23615 f9cf127de1aa859cfa0d5396d4a96055 97 Gene3D G3DSA:1.10.3340.10 1 84 5.3E-43 T 13-09-2016 IPR023163 SMc04008-like domain THL1_RS08965 4077b731ceebd58a44f40aceb3e35095 199 SMART SM00271 142 199 5.4E-6 T 13-09-2016 IPR001623 DnaJ domain THL1_RS08965 4077b731ceebd58a44f40aceb3e35095 199 SUPERFAMILY SSF46565 138 195 3.14E-12 T 13-09-2016 IPR001623 DnaJ domain THL1_RS08965 4077b731ceebd58a44f40aceb3e35095 199 Gene3D G3DSA:1.10.287.110 134 196 2.2E-14 T 13-09-2016 IPR001623 DnaJ domain THL1_RS08965 4077b731ceebd58a44f40aceb3e35095 199 Pfam PF12339 DNA-J related protein 11 135 2.1E-40 T 13-09-2016 IPR021059 DnaJ-related protein, N-terminal THL1_RS16375 3653a36fac9f073c3c2e6802e66fe1dc 139 Gene3D G3DSA:3.10.129.10 8 133 2.0E-36 T 13-09-2016 IPR029069 HotDog domain THL1_RS16375 3653a36fac9f073c3c2e6802e66fe1dc 139 SUPERFAMILY SSF54637 6 133 7.94E-32 T 13-09-2016 IPR029069 HotDog domain THL1_RS16375 3653a36fac9f073c3c2e6802e66fe1dc 139 Pfam PF13279 Thioesterase-like superfamily 14 133 8.8E-14 T 13-09-2016 THL1_RS16375 3653a36fac9f073c3c2e6802e66fe1dc 139 PANTHER PTHR31793 7 133 5.3E-29 T 13-09-2016 THL1_RS11005 f3a069aa006d11e96d9554457fe0dfe0 154 Gene3D G3DSA:3.40.50.1240 1 150 3.2E-31 T 13-09-2016 IPR029033 Histidine phosphatase superfamily THL1_RS11005 f3a069aa006d11e96d9554457fe0dfe0 154 SMART SM00855 2 110 2.5E-7 T 13-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 THL1_RS11005 f3a069aa006d11e96d9554457fe0dfe0 154 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 66 2.5E-12 T 13-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 THL1_RS11005 f3a069aa006d11e96d9554457fe0dfe0 154 SUPERFAMILY SSF53254 1 136 5.05E-22 T 13-09-2016 IPR029033 Histidine phosphatase superfamily THL1_RS11005 f3a069aa006d11e96d9554457fe0dfe0 154 TIGRFAM TIGR00249 sixA: phosphohistidine phosphatase SixA 1 129 1.1E-24 T 13-09-2016 IPR004449 Phosphohistidine phosphatase SixA GO:0005737|GO:0006464|GO:0008969 KEGG: 00051+3.1.3.-|KEGG: 00332+3.1.3.-|KEGG: 00565+3.1.3.-|KEGG: 00600+3.1.3.-|KEGG: 00730+3.1.3.-|KEGG: 00740+3.1.3.-|KEGG: 00760+3.1.3.- THL1_RS27235 e546213b89e8174362a77d79b250a767 333 PANTHER PTHR30006 7 330 1.0E-149 T 13-09-2016 THL1_RS27235 e546213b89e8174362a77d79b250a767 333 Gene3D G3DSA:3.40.190.10 125 264 7.0E-53 T 13-09-2016 THL1_RS27235 e546213b89e8174362a77d79b250a767 333 Gene3D G3DSA:3.40.190.10 265 305 7.7E-31 T 13-09-2016 THL1_RS27235 e546213b89e8174362a77d79b250a767 333 Gene3D G3DSA:3.40.190.10 7 121 7.7E-31 T 13-09-2016 THL1_RS27235 e546213b89e8174362a77d79b250a767 333 Pfam PF13343 Bacterial extracellular solute-binding protein 73 298 5.8E-21 T 13-09-2016 THL1_RS27235 e546213b89e8174362a77d79b250a767 333 PIRSF PIRSF002825 1 333 3.4E-101 T 13-09-2016 IPR026045 Ferric binding protein THL1_RS27235 e546213b89e8174362a77d79b250a767 333 PANTHER PTHR30006:SF4 7 330 1.0E-149 T 13-09-2016 THL1_RS27235 e546213b89e8174362a77d79b250a767 333 SUPERFAMILY SSF53850 25 329 3.52E-79 T 13-09-2016 THL1_RS18130 bd959f7458afb7704f24a84d06ba707a 188 Pfam PF04542 Sigma-70 region 2 31 98 1.8E-19 T 13-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS18130 bd959f7458afb7704f24a84d06ba707a 188 PANTHER PTHR30173 2 183 4.2E-87 T 13-09-2016 THL1_RS18130 bd959f7458afb7704f24a84d06ba707a 188 Gene3D G3DSA:1.10.1740.10 5 119 1.3E-32 T 13-09-2016 THL1_RS18130 bd959f7458afb7704f24a84d06ba707a 188 SUPERFAMILY SSF88946 9 116 4.87E-27 T 13-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS18130 bd959f7458afb7704f24a84d06ba707a 188 Gene3D G3DSA:1.10.10.10 128 183 2.1E-10 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS18130 bd959f7458afb7704f24a84d06ba707a 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 181 1.3E-30 T 13-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS18130 bd959f7458afb7704f24a84d06ba707a 188 PANTHER PTHR30173:SF26 2 183 4.2E-87 T 13-09-2016 THL1_RS18130 bd959f7458afb7704f24a84d06ba707a 188 SUPERFAMILY SSF88659 121 182 1.42E-10 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS18130 bd959f7458afb7704f24a84d06ba707a 188 Pfam PF04545 Sigma-70, region 4 131 180 9.5E-12 T 13-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS03875 e3ddfee87fea390dfc03e25ba3691a70 166 PANTHER PTHR36305 7 166 1.2E-65 T 13-09-2016 THL1_RS03875 e3ddfee87fea390dfc03e25ba3691a70 166 SUPERFAMILY SSF101307 16 162 5.76E-46 T 13-09-2016 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 THL1_RS03875 e3ddfee87fea390dfc03e25ba3691a70 166 Pfam PF04608 Phosphatidylglycerophosphatase A 22 161 2.5E-52 T 13-09-2016 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 THL1_RS03875 e3ddfee87fea390dfc03e25ba3691a70 166 PIRSF PIRSF006162 13 166 7.3E-50 T 13-09-2016 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 THL1_RS05410 060516e954e31388a5a2c6f63efc54b4 214 PIRSF PIRSF004649 1 209 9.6E-57 T 13-09-2016 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC THL1_RS05410 060516e954e31388a5a2c6f63efc54b4 214 Pfam PF05494 MlaC protein 31 196 5.0E-39 T 13-09-2016 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC THL1_RS05410 060516e954e31388a5a2c6f63efc54b4 214 Gene3D G3DSA:1.10.10.640 168 203 2.8E-18 T 13-09-2016 IPR023094 Toluene tolerance protein, alpha-helical THL1_RS05410 060516e954e31388a5a2c6f63efc54b4 214 Gene3D G3DSA:1.10.10.640 70 111 2.8E-18 T 13-09-2016 IPR023094 Toluene tolerance protein, alpha-helical THL1_RS05410 060516e954e31388a5a2c6f63efc54b4 214 PANTHER PTHR36573 1 210 5.7E-63 T 13-09-2016 THL1_RS05410 060516e954e31388a5a2c6f63efc54b4 214 Gene3D G3DSA:3.10.450.50 25 69 1.5E-19 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS05410 060516e954e31388a5a2c6f63efc54b4 214 Gene3D G3DSA:3.10.450.50 114 167 1.5E-19 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS14935 c9c7549acc934dcbb1823c677af9bf25 68 Gene3D G3DSA:1.20.5.230 25 68 6.7E-5 T 13-09-2016 THL1_RS14935 c9c7549acc934dcbb1823c677af9bf25 68 Pfam PF10389 Bacteriophage coat protein B 24 68 1.7E-12 T 13-09-2016 IPR008020 Capsid protein G8P GO:0019028 THL1_RS14995 c9c7549acc934dcbb1823c677af9bf25 68 Gene3D G3DSA:1.20.5.230 25 68 6.7E-5 T 13-09-2016 THL1_RS14995 c9c7549acc934dcbb1823c677af9bf25 68 Pfam PF10389 Bacteriophage coat protein B 24 68 1.7E-12 T 13-09-2016 IPR008020 Capsid protein G8P GO:0019028 THL1_RS07270 c5abe99fb90bbfd94ad94c1a408e59dc 369 SUPERFAMILY SSF55821 2 202 4.35E-86 T 13-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain THL1_RS07270 c5abe99fb90bbfd94ad94c1a408e59dc 369 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 3 199 9.9E-74 T 13-09-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS07270 c5abe99fb90bbfd94ad94c1a408e59dc 369 PANTHER PTHR21327:SF6 1 368 1.3E-135 T 13-09-2016 THL1_RS07270 c5abe99fb90bbfd94ad94c1a408e59dc 369 SUPERFAMILY SSF142695 204 367 1.31E-40 T 13-09-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 THL1_RS07270 c5abe99fb90bbfd94ad94c1a408e59dc 369 PIRSF PIRSF001259 1 369 7.7E-115 T 13-09-2016 THL1_RS07270 c5abe99fb90bbfd94ad94c1a408e59dc 369 Gene3D G3DSA:3.90.870.10 1 210 8.6E-99 T 13-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain THL1_RS07270 c5abe99fb90bbfd94ad94c1a408e59dc 369 Pfam PF00925 GTP cyclohydrolase II 208 365 2.4E-28 T 13-09-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 THL1_RS07270 c5abe99fb90bbfd94ad94c1a408e59dc 369 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 38.73 T 13-09-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS07270 c5abe99fb90bbfd94ad94c1a408e59dc 369 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 7 198 1.4E-82 T 13-09-2016 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00275 THL1_RS07270 c5abe99fb90bbfd94ad94c1a408e59dc 369 PANTHER PTHR21327 1 368 1.3E-135 T 13-09-2016 THL1_RS27740 06840bd1caa16345477b091e274d8be9 670 Gene3D G3DSA:3.40.50.300 280 382 3.0E-65 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27740 06840bd1caa16345477b091e274d8be9 670 Gene3D G3DSA:3.40.50.300 551 641 3.0E-65 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27740 06840bd1caa16345477b091e274d8be9 670 PANTHER PTHR11070:SF19 1 648 0.0 T 13-09-2016 THL1_RS27740 06840bd1caa16345477b091e274d8be9 670 Gene3D G3DSA:3.40.50.300 2 105 5.4E-67 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27740 06840bd1caa16345477b091e274d8be9 670 Gene3D G3DSA:3.40.50.300 182 279 5.4E-67 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27740 06840bd1caa16345477b091e274d8be9 670 Pfam PF00580 UvrD/REP helicase N-terminal domain 4 265 1.7E-73 T 13-09-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 THL1_RS27740 06840bd1caa16345477b091e274d8be9 670 Pfam PF13361 UvrD-like helicase C-terminal domain 271 613 2.7E-66 T 13-09-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 THL1_RS27740 06840bd1caa16345477b091e274d8be9 670 TIGRFAM TIGR01074 rep: ATP-dependent DNA helicase Rep 3 668 0.0 T 13-09-2016 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 THL1_RS27740 06840bd1caa16345477b091e274d8be9 670 PANTHER PTHR11070 1 648 0.0 T 13-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 THL1_RS27740 06840bd1caa16345477b091e274d8be9 670 SUPERFAMILY SSF52540 2 640 2.27E-164 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27740 06840bd1caa16345477b091e274d8be9 670 Gene3D G3DSA:1.10.10.160 109 181 2.3E-18 T 13-09-2016 IPR013986 DExx box DNA helicase domain THL1_RS27740 06840bd1caa16345477b091e274d8be9 670 Gene3D G3DSA:1.10.486.10 383 524 4.8E-36 T 13-09-2016 THL1_RS27740 06840bd1caa16345477b091e274d8be9 670 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 2 668 40.224 T 13-09-2016 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 THL1_RS25835 fcdb83bea662502e138668881ebdd7e3 394 PANTHER PTHR11476 10 361 3.5E-71 T 13-09-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 THL1_RS25835 fcdb83bea662502e138668881ebdd7e3 394 SUPERFAMILY SSF55681 7 324 1.47E-60 T 13-09-2016 THL1_RS25835 fcdb83bea662502e138668881ebdd7e3 394 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 19 372 34.803 T 13-09-2016 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 UniPathway: UPA00031 THL1_RS25835 fcdb83bea662502e138668881ebdd7e3 394 PANTHER PTHR11476:SF5 10 361 3.5E-71 T 13-09-2016 THL1_RS25835 fcdb83bea662502e138668881ebdd7e3 394 PIRSF PIRSF001549 7 381 1.0E-47 T 13-09-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 THL1_RS25835 fcdb83bea662502e138668881ebdd7e3 394 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 15 324 2.4E-91 T 13-09-2016 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 UniPathway: UPA00031 THL1_RS25835 fcdb83bea662502e138668881ebdd7e3 394 Pfam PF13393 Histidyl-tRNA synthetase 12 321 1.2E-117 T 13-09-2016 THL1_RS25835 fcdb83bea662502e138668881ebdd7e3 394 Gene3D G3DSA:3.30.930.10 20 322 8.6E-70 T 13-09-2016 THL1_RS06115 50f7adc0a9a83ec76c6dc526cbec6660 481 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 360 369 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS06115 50f7adc0a9a83ec76c6dc526cbec6660 481 SUPERFAMILY SSF46689 360 467 2.96E-7 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS06115 50f7adc0a9a83ec76c6dc526cbec6660 481 SMART SM00448 8 119 2.6E-28 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS06115 50f7adc0a9a83ec76c6dc526cbec6660 481 PANTHER PTHR32071:SF33 10 473 4.7E-172 T 13-09-2016 THL1_RS06115 50f7adc0a9a83ec76c6dc526cbec6660 481 Gene3D G3DSA:1.10.10.60 427 467 3.3E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS06115 50f7adc0a9a83ec76c6dc526cbec6660 481 Pfam PF00072 Response regulator receiver domain 10 119 1.6E-24 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS06115 50f7adc0a9a83ec76c6dc526cbec6660 481 Gene3D G3DSA:1.10.8.60 320 392 8.9E-22 T 13-09-2016 THL1_RS06115 50f7adc0a9a83ec76c6dc526cbec6660 481 Pfam PF00158 Sigma-54 interaction domain 147 313 1.8E-64 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS06115 50f7adc0a9a83ec76c6dc526cbec6660 481 Gene3D G3DSA:3.40.50.300 143 319 5.5E-55 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06115 50f7adc0a9a83ec76c6dc526cbec6660 481 Pfam PF02954 Bacterial regulatory protein, Fis family 432 469 4.6E-9 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS06115 50f7adc0a9a83ec76c6dc526cbec6660 481 SUPERFAMILY SSF52172 8 192 6.26E-42 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS06115 50f7adc0a9a83ec76c6dc526cbec6660 481 SUPERFAMILY SSF52540 147 390 2.4E-66 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06115 50f7adc0a9a83ec76c6dc526cbec6660 481 SMART SM00382 167 310 5.7E-8 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS06115 50f7adc0a9a83ec76c6dc526cbec6660 481 PANTHER PTHR32071 10 473 4.7E-172 T 13-09-2016 THL1_RS06115 50f7adc0a9a83ec76c6dc526cbec6660 481 Gene3D G3DSA:3.40.50.2300 8 133 9.0E-35 T 13-09-2016 THL1_RS06115 50f7adc0a9a83ec76c6dc526cbec6660 481 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 233 248 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS10705 8355b82595e313897c52bca8a467f63d 222 PANTHER PTHR30586:SF1 1 214 1.3E-140 T 13-09-2016 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 THL1_RS10705 8355b82595e313897c52bca8a467f63d 222 Pfam PF02508 Rnf-Nqr subunit, membrane protein 8 194 8.3E-60 T 13-09-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 THL1_RS10705 8355b82595e313897c52bca8a467f63d 222 PANTHER PTHR30586 1 214 1.3E-140 T 13-09-2016 THL1_RS10705 8355b82595e313897c52bca8a467f63d 222 PIRSF PIRSF006102 2 212 1.6E-65 T 13-09-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 THL1_RS10705 8355b82595e313897c52bca8a467f63d 222 TIGRFAM TIGR01939 nqrD: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit 3 205 7.7E-105 T 13-09-2016 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 THL1_RS10705 8355b82595e313897c52bca8a467f63d 222 Hamap MF_00428 Na(+)-translocating NADH-quinone reductase subunit D [nqrD]. 1 206 36.048 T 13-09-2016 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D GO:0016655|GO:0055114 THL1_RS11190 e3ad85144ce9d847d15f6fb071dcac32 241 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS11190 e3ad85144ce9d847d15f6fb071dcac32 241 PANTHER PTHR24322 147 183 3.4E-48 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11190 e3ad85144ce9d847d15f6fb071dcac32 241 PANTHER PTHR24322 6 131 3.4E-48 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11190 e3ad85144ce9d847d15f6fb071dcac32 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 236 2.1E-58 T 13-09-2016 THL1_RS11190 e3ad85144ce9d847d15f6fb071dcac32 241 SUPERFAMILY SSF51735 2 238 5.67E-77 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11190 e3ad85144ce9d847d15f6fb071dcac32 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 1.6E-14 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11190 e3ad85144ce9d847d15f6fb071dcac32 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 1.6E-14 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11190 e3ad85144ce9d847d15f6fb071dcac32 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.6E-14 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11190 e3ad85144ce9d847d15f6fb071dcac32 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.1E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11190 e3ad85144ce9d847d15f6fb071dcac32 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.1E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11190 e3ad85144ce9d847d15f6fb071dcac32 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 1.1E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11190 e3ad85144ce9d847d15f6fb071dcac32 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 1.1E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11190 e3ad85144ce9d847d15f6fb071dcac32 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 1.1E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11190 e3ad85144ce9d847d15f6fb071dcac32 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 1.1E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11190 e3ad85144ce9d847d15f6fb071dcac32 241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 184 0.0035 T 13-09-2016 THL1_RS11190 e3ad85144ce9d847d15f6fb071dcac32 241 Gene3D G3DSA:3.40.50.720 2 237 2.7E-77 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23340 d8973f5b5d75a6bbad12a75cd41df942 193 PIRSF PIRSF000349 1 193 2.4E-87 T 13-09-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 THL1_RS23340 d8973f5b5d75a6bbad12a75cd41df942 193 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 4.1E-23 T 13-09-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 THL1_RS23340 d8973f5b5d75a6bbad12a75cd41df942 193 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 4.1E-23 T 13-09-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 THL1_RS23340 d8973f5b5d75a6bbad12a75cd41df942 193 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 4.1E-23 T 13-09-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 THL1_RS23340 d8973f5b5d75a6bbad12a75cd41df942 193 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 4.1E-23 T 13-09-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 THL1_RS23340 d8973f5b5d75a6bbad12a75cd41df942 193 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 4.1E-23 T 13-09-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 THL1_RS23340 d8973f5b5d75a6bbad12a75cd41df942 193 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 81 2.8E-33 T 13-09-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 THL1_RS23340 d8973f5b5d75a6bbad12a75cd41df942 193 PANTHER PTHR11404 1 193 2.2E-114 T 13-09-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 THL1_RS23340 d8973f5b5d75a6bbad12a75cd41df942 193 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 13-09-2016 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 THL1_RS23340 d8973f5b5d75a6bbad12a75cd41df942 193 SUPERFAMILY SSF54719 84 192 1.27E-46 T 13-09-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 THL1_RS23340 d8973f5b5d75a6bbad12a75cd41df942 193 Gene3D G3DSA:1.10.287.990 20 82 5.9E-24 T 13-09-2016 THL1_RS23340 d8973f5b5d75a6bbad12a75cd41df942 193 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 189 6.0E-40 T 13-09-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 THL1_RS23340 d8973f5b5d75a6bbad12a75cd41df942 193 PANTHER PTHR11404:SF8 1 193 2.2E-114 T 13-09-2016 THL1_RS23340 d8973f5b5d75a6bbad12a75cd41df942 193 SUPERFAMILY SSF46609 1 84 7.2E-35 T 13-09-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 THL1_RS11285 0fcb9f2bbcdd51369045965367e8c87c 235 PANTHER PTHR11922 28 208 1.9E-66 T 13-09-2016 THL1_RS11285 0fcb9f2bbcdd51369045965367e8c87c 235 SUPERFAMILY SSF52317 3 198 6.42E-45 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS11285 0fcb9f2bbcdd51369045965367e8c87c 235 Gene3D G3DSA:3.40.50.880 2 231 5.8E-56 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS11285 0fcb9f2bbcdd51369045965367e8c87c 235 PANTHER PTHR11922:SF11 28 208 1.9E-66 T 13-09-2016 THL1_RS11285 0fcb9f2bbcdd51369045965367e8c87c 235 Pfam PF00117 Glutamine amidotransferase class-I 26 179 1.0E-15 T 13-09-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 THL1_RS07950 449b519bd97838e886c41aacd7f7806d 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 5.5E-12 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07950 449b519bd97838e886c41aacd7f7806d 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 5.5E-12 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07950 449b519bd97838e886c41aacd7f7806d 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 5.5E-12 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07950 449b519bd97838e886c41aacd7f7806d 208 PANTHER PTHR26402 8 197 1.0E-58 T 13-09-2016 THL1_RS07950 449b519bd97838e886c41aacd7f7806d 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 159 186 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07950 449b519bd97838e886c41aacd7f7806d 208 SUPERFAMILY SSF46894 134 199 1.16E-18 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS07950 449b519bd97838e886c41aacd7f7806d 208 Gene3D G3DSA:3.40.50.2300 10 146 1.1E-29 T 13-09-2016 THL1_RS07950 449b519bd97838e886c41aacd7f7806d 208 SMART SM00448 8 118 1.2E-23 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS07950 449b519bd97838e886c41aacd7f7806d 208 PANTHER PTHR26402:SF613 8 197 1.0E-58 T 13-09-2016 THL1_RS07950 449b519bd97838e886c41aacd7f7806d 208 SMART SM00421 142 199 4.6E-19 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07950 449b519bd97838e886c41aacd7f7806d 208 SUPERFAMILY SSF52172 8 151 2.28E-31 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS07950 449b519bd97838e886c41aacd7f7806d 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 197 2.2E-19 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07950 449b519bd97838e886c41aacd7f7806d 208 Gene3D G3DSA:1.10.10.10 147 199 1.2E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07950 449b519bd97838e886c41aacd7f7806d 208 Pfam PF00072 Response regulator receiver domain 10 118 1.5E-22 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS05315 1b2565d4a7698c31a9155c77a277678c 485 Pfam PF00575 S1 RNA binding domain 38 100 1.7E-8 T 13-09-2016 IPR003029 S1 domain GO:0003676 THL1_RS05315 1b2565d4a7698c31a9155c77a277678c 485 SUPERFAMILY SSF50249 39 118 4.44E-20 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS05315 1b2565d4a7698c31a9155c77a277678c 485 SMART SM00316 37 113 2.2E-10 T 13-09-2016 IPR022967 RNA-binding domain, S1 THL1_RS05315 1b2565d4a7698c31a9155c77a277678c 485 Gene3D G3DSA:2.40.50.140 30 119 1.6E-31 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS05315 1b2565d4a7698c31a9155c77a277678c 485 Pfam PF10150 Ribonuclease E/G family 115 389 5.1E-107 T 13-09-2016 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 THL1_RS05315 1b2565d4a7698c31a9155c77a277678c 485 PANTHER PTHR30001 1 485 3.9E-212 T 13-09-2016 THL1_RS05315 1b2565d4a7698c31a9155c77a277678c 485 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 14 422 8.4E-161 T 13-09-2016 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 THL1_RS08825 f839c6252a9b7d72d249f9218b45c10a 278 TIGRFAM TIGR03214 ura-cupin: putative allantoin catabolism protein 6 272 1.6E-116 T 13-09-2016 IPR017627 Conserved hypothetical protein CHP03214, putative allantoin-urate catabolism protein KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 THL1_RS08825 f839c6252a9b7d72d249f9218b45c10a 278 SUPERFAMILY SSF51182 10 272 2.68E-85 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS08825 f839c6252a9b7d72d249f9218b45c10a 278 Pfam PF07883 Cupin domain 195 252 1.5E-7 T 13-09-2016 IPR013096 Cupin 2, conserved barrel THL1_RS08825 f839c6252a9b7d72d249f9218b45c10a 278 Pfam PF07883 Cupin domain 72 141 2.2E-12 T 13-09-2016 IPR013096 Cupin 2, conserved barrel THL1_RS08825 f839c6252a9b7d72d249f9218b45c10a 278 PANTHER PTHR34571:SF1 6 272 3.5E-85 T 13-09-2016 THL1_RS08825 f839c6252a9b7d72d249f9218b45c10a 278 PANTHER PTHR34571 6 272 3.5E-85 T 13-09-2016 THL1_RS08825 f839c6252a9b7d72d249f9218b45c10a 278 Gene3D G3DSA:2.60.120.10 127 276 1.7E-69 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS08825 f839c6252a9b7d72d249f9218b45c10a 278 Gene3D G3DSA:2.60.120.10 1 126 4.7E-46 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS14455 5fbf206e71b908c9c1299a3979a212bb 300 Gene3D G3DSA:3.40.190.10 183 255 1.2E-11 T 13-09-2016 THL1_RS14455 5fbf206e71b908c9c1299a3979a212bb 300 Gene3D G3DSA:1.10.10.10 6 87 2.5E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14455 5fbf206e71b908c9c1299a3979a212bb 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 4.6E-18 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14455 5fbf206e71b908c9c1299a3979a212bb 300 SUPERFAMILY SSF53850 89 295 2.33E-26 T 13-09-2016 THL1_RS14455 5fbf206e71b908c9c1299a3979a212bb 300 Gene3D G3DSA:3.40.190.10 91 182 6.6E-9 T 13-09-2016 THL1_RS14455 5fbf206e71b908c9c1299a3979a212bb 300 PANTHER PTHR30126:SF29 3 293 2.3E-63 T 13-09-2016 THL1_RS14455 5fbf206e71b908c9c1299a3979a212bb 300 Pfam PF03466 LysR substrate binding domain 88 293 4.6E-22 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS14455 5fbf206e71b908c9c1299a3979a212bb 300 PANTHER PTHR30126 3 293 2.3E-63 T 13-09-2016 THL1_RS14455 5fbf206e71b908c9c1299a3979a212bb 300 SUPERFAMILY SSF46785 6 88 5.99E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS18630 4dff797cbd5442ba867087fb73964d6c 345 PANTHER PTHR30518 1 341 1.5E-91 T 13-09-2016 THL1_RS18630 4dff797cbd5442ba867087fb73964d6c 345 Gene3D G3DSA:3.30.160.60 303 336 2.3E-17 T 13-09-2016 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 THL1_RS18630 4dff797cbd5442ba867087fb73964d6c 345 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 3 330 7.2E-77 T 13-09-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like THL1_RS18630 4dff797cbd5442ba867087fb73964d6c 345 PANTHER PTHR30518:SF2 1 341 1.5E-91 T 13-09-2016 THL1_RS18630 4dff797cbd5442ba867087fb73964d6c 345 Pfam PF02618 YceG-like family 44 328 6.8E-76 T 13-09-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 ProSitePatterns PS00450 Aconitase family signature 1. 345 361 - T 13-09-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 PANTHER PTHR11670 333 472 8.1E-280 T 13-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 473 61.6 T 13-09-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 PANTHER PTHR11670:SF38 333 472 8.1E-280 T 13-09-2016 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 Gene3D G3DSA:3.30.499.10 341 472 6.7E-61 T 13-09-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 Gene3D G3DSA:3.30.499.10 300 309 6.7E-61 T 13-09-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 PANTHER PTHR11670:SF38 1 313 8.1E-280 T 13-09-2016 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 ProSitePatterns PS01244 Aconitase family signature 2. 406 419 - T 13-09-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 PRINTS PR00415 Aconitase family signature 139 154 9.3E-48 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 PRINTS PR00415 Aconitase family signature 215 228 9.3E-48 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 PRINTS PR00415 Aconitase family signature 292 306 9.3E-48 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 PRINTS PR00415 Aconitase family signature 114 122 9.3E-48 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 PRINTS PR00415 Aconitase family signature 125 138 9.3E-48 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 PRINTS PR00415 Aconitase family signature 349 360 9.3E-48 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 PRINTS PR00415 Aconitase family signature 406 419 9.3E-48 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 PRINTS PR00415 Aconitase family signature 88 101 9.3E-48 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 PRINTS PR00415 Aconitase family signature 201 214 9.3E-48 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 Gene3D G3DSA:3.40.1060.10 172 285 3.0E-39 T 13-09-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 Pfam PF00330 Aconitase family (aconitate hydratase) 8 464 3.9E-154 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 SUPERFAMILY SSF53732 2 472 4.58E-163 T 13-09-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 PANTHER PTHR11670 1 313 8.1E-280 T 13-09-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 Gene3D G3DSA:3.30.499.10 4 163 7.1E-21 T 13-09-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS10015 7e7916cce1dd8c144e4f638665b924d1 474 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 472 5.2E-234 T 13-09-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS06350 9a6ce096249e184c08dec5b38a5cd850 258 Gene3D G3DSA:3.40.190.10 23 111 5.7E-47 T 13-09-2016 THL1_RS06350 9a6ce096249e184c08dec5b38a5cd850 258 Gene3D G3DSA:3.40.190.10 213 255 5.7E-47 T 13-09-2016 THL1_RS06350 9a6ce096249e184c08dec5b38a5cd850 258 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 3 251 1.9E-86 T 13-09-2016 IPR005768 Lysine-arginine-ornithine-binding periplasmic protein GO:0005215|GO:0006810|GO:0030288 THL1_RS06350 9a6ce096249e184c08dec5b38a5cd850 258 SUPERFAMILY SSF53850 1 255 9.31E-71 T 13-09-2016 THL1_RS06350 9a6ce096249e184c08dec5b38a5cd850 258 SMART SM00062 25 254 4.2E-71 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS06350 9a6ce096249e184c08dec5b38a5cd850 258 PANTHER PTHR18966:SF152 26 251 8.7E-68 T 13-09-2016 THL1_RS06350 9a6ce096249e184c08dec5b38a5cd850 258 Gene3D G3DSA:3.40.190.10 113 211 1.3E-22 T 13-09-2016 THL1_RS06350 9a6ce096249e184c08dec5b38a5cd850 258 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 26 252 2.1E-63 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS06350 9a6ce096249e184c08dec5b38a5cd850 258 PANTHER PTHR18966 26 251 8.7E-68 T 13-09-2016 THL1_RS12285 0386acde89369da9c46305f48f053363 164 Gene3D G3DSA:3.40.30.10 84 162 9.3E-10 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS12285 0386acde89369da9c46305f48f053363 164 PIRSF PIRSF000216 4 164 3.3E-52 T 13-09-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 THL1_RS12285 0386acde89369da9c46305f48f053363 164 SUPERFAMILY SSF52833 13 163 8.61E-48 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS12285 0386acde89369da9c46305f48f053363 164 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 21 164 4.8E-50 T 13-09-2016 THL1_RS12285 0386acde89369da9c46305f48f053363 164 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 20 164 6.2E-47 T 13-09-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 THL1_RS12285 0386acde89369da9c46305f48f053363 164 PANTHER PTHR10371 1 164 5.7E-106 T 13-09-2016 THL1_RS12285 0386acde89369da9c46305f48f053363 164 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 121 139 - T 13-09-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 THL1_RS12285 0386acde89369da9c46305f48f053363 164 PANTHER PTHR10371:SF7 1 164 5.7E-106 T 13-09-2016 THL1_RS01880 04b4a8e304f520a4f14853f348378c0b 246 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 24 138 3.7E-39 T 13-09-2016 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 THL1_RS01880 04b4a8e304f520a4f14853f348378c0b 246 PANTHER PTHR30251 15 232 2.4E-68 T 13-09-2016 THL1_RS01880 04b4a8e304f520a4f14853f348378c0b 246 Gene3D G3DSA:2.60.40.360 24 138 2.7E-41 T 13-09-2016 IPR008962 PapD-like THL1_RS01880 04b4a8e304f520a4f14853f348378c0b 246 SUPERFAMILY SSF49354 19 138 3.14E-38 T 13-09-2016 IPR008962 PapD-like THL1_RS01880 04b4a8e304f520a4f14853f348378c0b 246 PRINTS PR00969 Pili chaperone signature 159 174 1.8E-27 T 13-09-2016 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 THL1_RS01880 04b4a8e304f520a4f14853f348378c0b 246 PRINTS PR00969 Pili chaperone signature 97 114 1.8E-27 T 13-09-2016 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 THL1_RS01880 04b4a8e304f520a4f14853f348378c0b 246 PRINTS PR00969 Pili chaperone signature 25 34 1.8E-27 T 13-09-2016 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 THL1_RS01880 04b4a8e304f520a4f14853f348378c0b 246 PRINTS PR00969 Pili chaperone signature 69 90 1.8E-27 T 13-09-2016 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 THL1_RS01880 04b4a8e304f520a4f14853f348378c0b 246 PRINTS PR00969 Pili chaperone signature 120 135 1.8E-27 T 13-09-2016 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 THL1_RS01880 04b4a8e304f520a4f14853f348378c0b 246 Gene3D G3DSA:2.60.40.1070 143 225 4.6E-18 T 13-09-2016 IPR016148 Pili assembly chaperone, C-terminal THL1_RS01880 04b4a8e304f520a4f14853f348378c0b 246 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 164 223 2.0E-12 T 13-09-2016 IPR016148 Pili assembly chaperone, C-terminal THL1_RS01880 04b4a8e304f520a4f14853f348378c0b 246 SUPERFAMILY SSF49584 132 227 4.19E-16 T 13-09-2016 IPR016148 Pili assembly chaperone, C-terminal THL1_RS01880 04b4a8e304f520a4f14853f348378c0b 246 PANTHER PTHR30251:SF0 15 232 2.4E-68 T 13-09-2016 THL1_RS00215 9b5212edeb50981327b6b702869012e5 214 PANTHER PTHR18901:SF23 1 213 4.3E-83 T 13-09-2016 THL1_RS00215 9b5212edeb50981327b6b702869012e5 214 Gene3D G3DSA:3.40.50.1000 76 211 1.8E-38 T 13-09-2016 IPR023214 HAD-like domain THL1_RS00215 9b5212edeb50981327b6b702869012e5 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 183 3.8E-29 T 13-09-2016 IPR023214 HAD-like domain THL1_RS00215 9b5212edeb50981327b6b702869012e5 214 PANTHER PTHR18901 1 213 4.3E-83 T 13-09-2016 THL1_RS00215 9b5212edeb50981327b6b702869012e5 214 SUPERFAMILY SSF56784 1 210 2.76E-51 T 13-09-2016 IPR023214 HAD-like domain THL1_RS00215 9b5212edeb50981327b6b702869012e5 214 Gene3D G3DSA:1.10.150.240 17 75 3.6E-24 T 13-09-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 THL1_RS07500 e1c1c27c191fc59db0bd0ae24d9b6038 376 Gene3D G3DSA:2.40.30.110 289 372 7.2E-11 T 13-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS07500 e1c1c27c191fc59db0bd0ae24d9b6038 376 Pfam PF01571 Aminomethyltransferase folate-binding domain 11 245 2.2E-61 T 13-09-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal THL1_RS07500 e1c1c27c191fc59db0bd0ae24d9b6038 376 Gene3D G3DSA:3.30.70.1400 57 125 3.6E-20 T 13-09-2016 THL1_RS07500 e1c1c27c191fc59db0bd0ae24d9b6038 376 PIRSF PIRSF006487 1 376 7.1E-84 T 13-09-2016 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS07500 e1c1c27c191fc59db0bd0ae24d9b6038 376 SUPERFAMILY SSF101790 290 372 5.72E-13 T 13-09-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain THL1_RS07500 e1c1c27c191fc59db0bd0ae24d9b6038 376 SUPERFAMILY SSF103025 5 284 7.53E-70 T 13-09-2016 THL1_RS07500 e1c1c27c191fc59db0bd0ae24d9b6038 376 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 274 350 2.6E-7 T 13-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS07500 e1c1c27c191fc59db0bd0ae24d9b6038 376 Gene3D G3DSA:3.30.1360.120 141 233 1.5E-25 T 13-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 195 204 2.2E-21 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 235 244 2.2E-21 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 133 145 2.2E-21 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 210 229 2.2E-21 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 301 309 2.2E-21 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 Pfam PF00970 Oxidoreductase FAD-binding domain 109 201 1.6E-11 T 13-09-2016 IPR008333 Oxidoreductase, FAD-binding domain THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 Gene3D G3DSA:3.10.20.30 16 96 5.3E-26 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 SUPERFAMILY SSF63380 105 201 2.08E-18 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 Gene3D G3DSA:2.40.30.10 106 202 4.3E-20 T 13-09-2016 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 PANTHER PTHR19370:SF68 37 333 1.3E-50 T 13-09-2016 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 235 244 1.3E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 301 309 1.3E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 210 229 1.3E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 Pfam PF00175 Oxidoreductase NAD-binding domain 211 314 1.0E-18 T 13-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 PANTHER PTHR19370 37 333 1.3E-50 T 13-09-2016 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 16 88 4.3E-17 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 Gene3D G3DSA:3.40.50.80 205 334 1.6E-35 T 13-09-2016 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 43 51 - T 13-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 SUPERFAMILY SSF52343 191 331 3.93E-35 T 13-09-2016 THL1_RS13405 d0af623e01fff9081c6293e913c56fd9 344 SUPERFAMILY SSF54292 12 95 6.42E-27 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS11050 571c518441b7ec342d46072492a7abdf 358 Gene3D G3DSA:2.40.370.10 49 236 1.9E-69 T 13-09-2016 IPR023374 AttH-like domain THL1_RS11050 571c518441b7ec342d46072492a7abdf 358 Pfam PF17186 Lipocalin-like domain 236 358 5.9E-42 T 13-09-2016 IPR033451 AttH, lipocalin-like domain THL1_RS11050 571c518441b7ec342d46072492a7abdf 358 PANTHER PTHR38591 28 358 3.6E-103 T 13-09-2016 THL1_RS11050 571c518441b7ec342d46072492a7abdf 358 SUPERFAMILY SSF159245 38 358 7.59E-106 T 13-09-2016 THL1_RS11050 571c518441b7ec342d46072492a7abdf 358 Pfam PF07143 CrtC N-terminal lipocalin domain 61 233 3.3E-54 T 13-09-2016 IPR010791 AttH domain THL1_RS11050 571c518441b7ec342d46072492a7abdf 358 Gene3D G3DSA:2.40.370.10 238 358 5.9E-42 T 13-09-2016 IPR023374 AttH-like domain THL1_RS19145 a531da16d5bb022d36c207ddb43737e6 358 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 121 347 1.8E-16 T 13-09-2016 IPR005079 Peptidase C45 THL1_RS19145 a531da16d5bb022d36c207ddb43737e6 358 PANTHER PTHR34180 1 348 6.2E-30 T 13-09-2016 THL1_RS25460 5b80fce26467be3c924de8d8e0945cd6 147 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 147 75.386 T 13-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS25460 5b80fce26467be3c924de8d8e0945cd6 147 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 13-09-2016 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS25460 5b80fce26467be3c924de8d8e0945cd6 147 PANTHER PTHR21272 1 146 1.3E-90 T 13-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS25460 5b80fce26467be3c924de8d8e0945cd6 147 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 143 3.1E-61 T 13-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS25460 5b80fce26467be3c924de8d8e0945cd6 147 SUPERFAMILY SSF52304 3 145 1.96E-63 T 13-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS25460 5b80fce26467be3c924de8d8e0945cd6 147 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 17 142 6.0E-64 T 13-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS25460 5b80fce26467be3c924de8d8e0945cd6 147 Gene3D G3DSA:3.40.50.9100 2 145 2.7E-67 T 13-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS25460 5b80fce26467be3c924de8d8e0945cd6 147 Pfam PF01220 Dehydroquinase class II 4 140 1.3E-59 T 13-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS25460 5b80fce26467be3c924de8d8e0945cd6 147 PIRSF PIRSF001399 1 146 5.6E-59 T 13-09-2016 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 THL1_RS19560 bb85a4711291aa0ad75ad195fc8bf707 323 PANTHER PTHR30034 4 323 6.4E-150 T 13-09-2016 THL1_RS19560 bb85a4711291aa0ad75ad195fc8bf707 323 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 5 320 2.8E-108 T 13-09-2016 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 THL1_RS19560 bb85a4711291aa0ad75ad195fc8bf707 323 PRINTS PR00955 Flagellar motor switch protein FliM signature 114 133 5.8E-21 T 13-09-2016 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 THL1_RS19560 bb85a4711291aa0ad75ad195fc8bf707 323 PRINTS PR00955 Flagellar motor switch protein FliM signature 4 17 5.8E-21 T 13-09-2016 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 THL1_RS19560 bb85a4711291aa0ad75ad195fc8bf707 323 PRINTS PR00955 Flagellar motor switch protein FliM signature 89 105 5.8E-21 T 13-09-2016 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 THL1_RS19560 bb85a4711291aa0ad75ad195fc8bf707 323 PRINTS PR00955 Flagellar motor switch protein FliM signature 211 229 5.8E-21 T 13-09-2016 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 THL1_RS19560 bb85a4711291aa0ad75ad195fc8bf707 323 Pfam PF02154 Flagellar motor switch protein FliM 38 229 1.4E-73 T 13-09-2016 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 THL1_RS19560 bb85a4711291aa0ad75ad195fc8bf707 323 SUPERFAMILY SSF103039 55 230 2.88E-19 T 13-09-2016 IPR028976 CheC-like domain THL1_RS19560 bb85a4711291aa0ad75ad195fc8bf707 323 SUPERFAMILY SSF103039 6 15 2.88E-19 T 13-09-2016 IPR028976 CheC-like domain THL1_RS19560 bb85a4711291aa0ad75ad195fc8bf707 323 PANTHER PTHR30034:SF0 4 323 6.4E-150 T 13-09-2016 THL1_RS19560 bb85a4711291aa0ad75ad195fc8bf707 323 SUPERFAMILY SSF101801 247 321 1.7E-14 T 13-09-2016 IPR001543 Surface presentation of antigen (SpoA) THL1_RS19560 bb85a4711291aa0ad75ad195fc8bf707 323 PIRSF PIRSF002888 3 323 3.9E-91 T 13-09-2016 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 THL1_RS19560 bb85a4711291aa0ad75ad195fc8bf707 323 Gene3D G3DSA:2.30.330.10 240 321 9.0E-10 T 13-09-2016 THL1_RS19560 bb85a4711291aa0ad75ad195fc8bf707 323 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 251 319 4.1E-17 T 13-09-2016 IPR001543 Surface presentation of antigen (SpoA) THL1_RS00740 2383acd1fce1c718c19a00e1da8812ce 342 Pfam PF11168 Protein of unknown function (DUF2955) 14 153 3.9E-45 T 13-09-2016 IPR022604 Protein of unknown function DUF2955 THL1_RS00740 2383acd1fce1c718c19a00e1da8812ce 342 PIRSF PIRSF029594 7 341 6.6E-142 T 13-09-2016 IPR016926 Uncharacterised conserved protein UCP029594 THL1_RS00740 2383acd1fce1c718c19a00e1da8812ce 342 Pfam PF13515 Fusaric acid resistance protein-like 190 321 8.3E-8 T 13-09-2016 THL1_RS15835 a2da9199e1e1b7cd6d203b26d0c60481 210 SUPERFAMILY SSF50090 1 208 1.22E-57 T 13-09-2016 IPR008990 Electron transport accessory protein-like domain THL1_RS15835 a2da9199e1e1b7cd6d203b26d0c60481 210 Pfam PF02211 Nitrile hydratase beta subunit 1 207 2.2E-57 T 13-09-2016 IPR024690 Nitrile hydratase beta subunit domain GO:0018822 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 THL1_RS15835 a2da9199e1e1b7cd6d203b26d0c60481 210 Gene3D G3DSA:1.10.472.20 1 125 1.4E-32 T 13-09-2016 THL1_RS15835 a2da9199e1e1b7cd6d203b26d0c60481 210 TIGRFAM TIGR03888 nitrile_beta: nitrile hydratase, beta subunit 1 207 8.1E-65 T 13-09-2016 IPR003168 Nitrile hydratase, beta subunit GO:0006807|GO:0018822|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 THL1_RS15835 a2da9199e1e1b7cd6d203b26d0c60481 210 Gene3D G3DSA:2.30.30.50 126 207 7.3E-31 T 13-09-2016 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 PANTHER PTHR19370:SF89 19 272 1.1E-126 T 13-09-2016 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 Pfam PF00970 Oxidoreductase FAD-binding domain 25 116 3.3E-18 T 13-09-2016 IPR008333 Oxidoreductase, FAD-binding domain THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 PANTHER PTHR19370 19 272 1.1E-126 T 13-09-2016 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 PRINTS PR00406 Cytochrome B5 reductase signature 127 146 7.4E-9 T 13-09-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 PRINTS PR00406 Cytochrome B5 reductase signature 164 175 7.4E-9 T 13-09-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 PRINTS PR00406 Cytochrome B5 reductase signature 104 118 7.4E-9 T 13-09-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 PRINTS PR00406 Cytochrome B5 reductase signature 220 228 7.4E-9 T 13-09-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 PRINTS PR00406 Cytochrome B5 reductase signature 67 74 7.4E-9 T 13-09-2016 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 317 325 - T 13-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 SUPERFAMILY SSF63380 12 117 8.82E-30 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 Gene3D G3DSA:3.10.20.30 246 366 2.8E-30 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 67 74 6.2E-5 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 164 175 6.2E-5 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 127 146 6.2E-5 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 220 228 6.2E-5 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 Gene3D G3DSA:3.40.50.80 107 245 4.3E-34 T 13-09-2016 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 Gene3D G3DSA:2.40.30.10 19 106 3.8E-29 T 13-09-2016 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 Pfam PF00175 Oxidoreductase NAD-binding domain 128 233 2.4E-13 T 13-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 288 360 9.1E-13 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 SUPERFAMILY SSF54292 243 366 1.7E-27 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS01895 4d0d0af641c3b2cfdff20c1095b679c9 367 SUPERFAMILY SSF52343 107 250 9.43E-35 T 13-09-2016 THL1_RS25230 ecd8a1ea29ef80323cc5dc5b227f3eeb 434 PANTHER PTHR37419:SF3 5 319 4.3E-58 T 13-09-2016 THL1_RS25230 ecd8a1ea29ef80323cc5dc5b227f3eeb 434 PANTHER PTHR37419 5 319 4.3E-58 T 13-09-2016 THL1_RS25230 ecd8a1ea29ef80323cc5dc5b227f3eeb 434 Pfam PF07805 HipA-like N-terminal domain 147 227 7.2E-18 T 13-09-2016 IPR012894 HipA, N-terminal subdomain 2 THL1_RS25230 ecd8a1ea29ef80323cc5dc5b227f3eeb 434 Pfam PF13657 HipA N-terminal domain 5 106 3.5E-19 T 13-09-2016 IPR017508 HipA, N-terminal subdomain 1 THL1_RS25230 ecd8a1ea29ef80323cc5dc5b227f3eeb 434 Pfam PF07804 HipA-like C-terminal domain 236 381 8.0E-32 T 13-09-2016 IPR012893 HipA-like, C-terminal THL1_RS25230 ecd8a1ea29ef80323cc5dc5b227f3eeb 434 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 4 106 2.9E-20 T 13-09-2016 IPR017508 HipA, N-terminal subdomain 1 THL1_RS11500 65393e125ec4c0677f778378ad9a9d4c 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 6.8E-6 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS11500 65393e125ec4c0677f778378ad9a9d4c 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 6.8E-6 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS11500 65393e125ec4c0677f778378ad9a9d4c 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 56 72 6.8E-6 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS11500 65393e125ec4c0677f778378ad9a9d4c 148 PANTHER PTHR33164:SF5 3 144 5.6E-54 T 13-09-2016 THL1_RS11500 65393e125ec4c0677f778378ad9a9d4c 148 Gene3D G3DSA:1.10.10.10 6 144 1.1E-41 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11500 65393e125ec4c0677f778378ad9a9d4c 148 PANTHER PTHR33164 3 144 5.6E-54 T 13-09-2016 THL1_RS11500 65393e125ec4c0677f778378ad9a9d4c 148 SMART SM00347 32 130 1.6E-24 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS11500 65393e125ec4c0677f778378ad9a9d4c 148 Pfam PF01047 MarR family 39 97 2.4E-15 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS11500 65393e125ec4c0677f778378ad9a9d4c 148 SUPERFAMILY SSF46785 2 144 5.24E-35 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS03255 3bafee2a73dec1fe1f1f52f5521246f9 300 Pfam PF03466 LysR substrate binding domain 98 296 2.1E-23 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS03255 3bafee2a73dec1fe1f1f52f5521246f9 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 1.8E-12 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS03255 3bafee2a73dec1fe1f1f52f5521246f9 300 SUPERFAMILY SSF46785 8 88 2.38E-15 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS03255 3bafee2a73dec1fe1f1f52f5521246f9 300 PANTHER PTHR30118:SF8 1 298 1.6E-88 T 13-09-2016 THL1_RS03255 3bafee2a73dec1fe1f1f52f5521246f9 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 8.1E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS03255 3bafee2a73dec1fe1f1f52f5521246f9 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 8.1E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS03255 3bafee2a73dec1fe1f1f52f5521246f9 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 8.1E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS03255 3bafee2a73dec1fe1f1f52f5521246f9 300 Gene3D G3DSA:3.40.190.10 273 299 8.6E-25 T 13-09-2016 THL1_RS03255 3bafee2a73dec1fe1f1f52f5521246f9 300 Gene3D G3DSA:3.40.190.10 93 176 8.6E-25 T 13-09-2016 THL1_RS03255 3bafee2a73dec1fe1f1f52f5521246f9 300 PANTHER PTHR30118 1 298 1.6E-88 T 13-09-2016 THL1_RS03255 3bafee2a73dec1fe1f1f52f5521246f9 300 Gene3D G3DSA:3.40.190.10 183 269 4.5E-24 T 13-09-2016 THL1_RS03255 3bafee2a73dec1fe1f1f52f5521246f9 300 Gene3D G3DSA:1.10.10.10 2 87 1.6E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS03255 3bafee2a73dec1fe1f1f52f5521246f9 300 SUPERFAMILY SSF53850 93 297 6.83E-36 T 13-09-2016 THL1_RS22320 6312b5c6cdc3956d74d8258ee41d2c5f 327 SUPERFAMILY SSF52283 2 132 1.32E-37 T 13-09-2016 THL1_RS22320 6312b5c6cdc3956d74d8258ee41d2c5f 327 SUPERFAMILY SSF51735 100 296 5.85E-59 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS22320 6312b5c6cdc3956d74d8258ee41d2c5f 327 PANTHER PTHR10996:SF161 1 322 3.2E-160 T 13-09-2016 THL1_RS22320 6312b5c6cdc3956d74d8258ee41d2c5f 327 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 13-09-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site THL1_RS22320 6312b5c6cdc3956d74d8258ee41d2c5f 327 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 145 172 - T 13-09-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 THL1_RS22320 6312b5c6cdc3956d74d8258ee41d2c5f 327 PANTHER PTHR10996 1 322 3.2E-160 T 13-09-2016 THL1_RS22320 6312b5c6cdc3956d74d8258ee41d2c5f 327 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 192 214 - T 13-09-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site THL1_RS22320 6312b5c6cdc3956d74d8258ee41d2c5f 327 Gene3D G3DSA:3.40.50.720 117 295 1.3E-63 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS22320 6312b5c6cdc3956d74d8258ee41d2c5f 327 Gene3D G3DSA:3.40.50.720 16 116 5.8E-31 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS22320 6312b5c6cdc3956d74d8258ee41d2c5f 327 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 295 4.3E-59 T 13-09-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 THL1_RS22320 6312b5c6cdc3956d74d8258ee41d2c5f 327 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 19 321 6.0E-30 T 13-09-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 THL1_RS24950 7161bb59fed21f017eb943a4047bd19e 222 PANTHER PTHR30055 11 216 2.7E-84 T 13-09-2016 THL1_RS24950 7161bb59fed21f017eb943a4047bd19e 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 74 4.3E-14 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS24950 7161bb59fed21f017eb943a4047bd19e 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 7.7E-7 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS24950 7161bb59fed21f017eb943a4047bd19e 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 7.7E-7 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS24950 7161bb59fed21f017eb943a4047bd19e 222 Gene3D G3DSA:1.10.357.10 75 216 3.1E-56 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS24950 7161bb59fed21f017eb943a4047bd19e 222 Gene3D G3DSA:1.10.10.60 18 74 2.4E-19 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS24950 7161bb59fed21f017eb943a4047bd19e 222 SUPERFAMILY SSF48498 92 216 1.64E-42 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS24950 7161bb59fed21f017eb943a4047bd19e 222 SUPERFAMILY SSF46689 16 96 6.16E-18 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS24950 7161bb59fed21f017eb943a4047bd19e 222 PANTHER PTHR30055:SF42 11 216 2.7E-84 T 13-09-2016 THL1_RS24950 7161bb59fed21f017eb943a4047bd19e 222 Pfam PF08362 YcdC-like protein, C-terminal region 75 216 5.9E-53 T 13-09-2016 IPR013573 Transcription regulator YcdC, C-terminal GO:0045892 THL1_RS28080 fe76d0a641d8e0c4ea79459f0de3804a 302 Pfam PF01263 Aldose 1-epimerase 24 296 3.7E-55 T 13-09-2016 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 THL1_RS28080 fe76d0a641d8e0c4ea79459f0de3804a 302 SUPERFAMILY SSF74650 5 294 6.09E-71 T 13-09-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 THL1_RS28080 fe76d0a641d8e0c4ea79459f0de3804a 302 PANTHER PTHR11122:SF14 7 297 9.9E-86 T 13-09-2016 THL1_RS28080 fe76d0a641d8e0c4ea79459f0de3804a 302 PANTHER PTHR11122 7 297 9.9E-86 T 13-09-2016 THL1_RS28080 fe76d0a641d8e0c4ea79459f0de3804a 302 PIRSF PIRSF016020 5 300 4.7E-61 T 13-09-2016 IPR025532 Glucose-6-phosphate 1-epimerase KEGG: 00010+5.1.3.15 THL1_RS28080 fe76d0a641d8e0c4ea79459f0de3804a 302 Gene3D G3DSA:2.70.98.10 7 297 1.0E-84 T 13-09-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 THL1_RS03095 771d5c19d38e505c4c4463e2f46c92cf 502 Gene3D G3DSA:3.30.420.10 157 277 2.1E-4 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS03095 771d5c19d38e505c4c4463e2f46c92cf 502 PANTHER PTHR35004 2 442 3.2E-81 T 13-09-2016 THL1_RS03095 771d5c19d38e505c4c4463e2f46c92cf 502 Pfam PF00665 Integrase core domain 128 252 2.0E-15 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS03095 771d5c19d38e505c4c4463e2f46c92cf 502 PANTHER PTHR35004:SF2 2 442 3.2E-81 T 13-09-2016 THL1_RS03095 771d5c19d38e505c4c4463e2f46c92cf 502 Gene3D G3DSA:1.10.10.60 12 47 2.0E-5 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS00900 ec3ae99ad1d5c99c59ff65ac6391fbfb 326 SUPERFAMILY SSF53850 28 247 7.27E-43 T 13-09-2016 THL1_RS00900 ec3ae99ad1d5c99c59ff65ac6391fbfb 326 TIGRFAM TIGR01729 taurine_ABC_bnd: taurine ABC transporter, periplasmic binding protein 29 325 1.3E-140 T 13-09-2016 IPR010068 Periplasmic binding protein TauA GO:0015734|GO:0042597 THL1_RS00900 ec3ae99ad1d5c99c59ff65ac6391fbfb 326 PANTHER PTHR30024 19 324 1.0E-84 T 13-09-2016 THL1_RS00900 ec3ae99ad1d5c99c59ff65ac6391fbfb 326 SMART SM00062 27 244 7.2E-7 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS00900 ec3ae99ad1d5c99c59ff65ac6391fbfb 326 Gene3D G3DSA:3.40.190.10 109 218 4.0E-21 T 13-09-2016 THL1_RS00900 ec3ae99ad1d5c99c59ff65ac6391fbfb 326 PANTHER PTHR30024:SF17 19 324 1.0E-84 T 13-09-2016 THL1_RS00900 ec3ae99ad1d5c99c59ff65ac6391fbfb 326 Gene3D G3DSA:3.40.190.10 65 104 2.0E-4 T 13-09-2016 THL1_RS00900 ec3ae99ad1d5c99c59ff65ac6391fbfb 326 Gene3D G3DSA:3.40.190.10 219 251 2.0E-4 T 13-09-2016 THL1_RS00900 ec3ae99ad1d5c99c59ff65ac6391fbfb 326 Pfam PF09084 NMT1/THI5 like 56 245 1.9E-22 T 13-09-2016 IPR015168 SsuA/THI5-like THL1_RS03365 a6b27b3b36cfd9bfbd0825f66ae9c184 141 TIGRFAM TIGR00701 TIGR00701: TIGR00701 family protein 3 141 4.4E-52 T 13-09-2016 IPR014351 Conserved hypothetical protein CHP00701 THL1_RS03365 a6b27b3b36cfd9bfbd0825f66ae9c184 141 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 141 1.8E-58 T 13-09-2016 IPR005265 Uncharacterised protein family UPF0093 THL1_RS03365 a6b27b3b36cfd9bfbd0825f66ae9c184 141 PIRSF PIRSF004638 1 141 1.4E-64 T 13-09-2016 IPR005265 Uncharacterised protein family UPF0093 THL1_RS03365 a6b27b3b36cfd9bfbd0825f66ae9c184 141 PANTHER PTHR40255 1 141 5.3E-65 T 13-09-2016 THL1_RS16495 630021a77d4581201ee25dcfd63cc679 705 PANTHER PTHR32089:SF34 24 336 6.8E-171 T 13-09-2016 THL1_RS16495 630021a77d4581201ee25dcfd63cc679 705 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 511 703 1.0E-48 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS16495 630021a77d4581201ee25dcfd63cc679 705 PANTHER PTHR32089 24 336 6.8E-171 T 13-09-2016 THL1_RS16495 630021a77d4581201ee25dcfd63cc679 705 PANTHER PTHR32089 353 705 6.8E-171 T 13-09-2016 THL1_RS16495 630021a77d4581201ee25dcfd63cc679 705 Gene3D G3DSA:3.30.450.20 195 339 8.6E-11 T 13-09-2016 THL1_RS16495 630021a77d4581201ee25dcfd63cc679 705 SMART SM00283 443 704 1.4E-74 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS16495 630021a77d4581201ee25dcfd63cc679 705 SUPERFAMILY SSF58104 396 705 1.31E-78 T 13-09-2016 THL1_RS16495 630021a77d4581201ee25dcfd63cc679 705 Pfam PF02743 Cache domain 94 326 9.4E-13 T 13-09-2016 IPR033479 Double Cache domain 1 THL1_RS16495 630021a77d4581201ee25dcfd63cc679 705 Pfam PF00672 HAMP domain 355 424 5.9E-11 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS16495 630021a77d4581201ee25dcfd63cc679 705 SMART SM00304 374 428 1.4E-6 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS16495 630021a77d4581201ee25dcfd63cc679 705 Gene3D G3DSA:1.10.287.950 461 674 1.9E-56 T 13-09-2016 THL1_RS16495 630021a77d4581201ee25dcfd63cc679 705 PANTHER PTHR32089:SF34 353 705 6.8E-171 T 13-09-2016 THL1_RS13185 2cb20818ce5616e71c5a48ca6c8dbd0e 439 PANTHER PTHR35093:SF2 16 439 4.0E-126 T 13-09-2016 THL1_RS13185 2cb20818ce5616e71c5a48ca6c8dbd0e 439 Gene3D G3DSA:2.40.160.60 39 439 9.0E-113 T 13-09-2016 THL1_RS13185 2cb20818ce5616e71c5a48ca6c8dbd0e 439 PANTHER PTHR35093 16 439 4.0E-126 T 13-09-2016 THL1_RS13185 2cb20818ce5616e71c5a48ca6c8dbd0e 439 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 31 439 1.3E-113 T 13-09-2016 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) THL1_RS13185 2cb20818ce5616e71c5a48ca6c8dbd0e 439 SUPERFAMILY SSF56935 39 439 1.16E-85 T 13-09-2016 THL1_RS25635 c44fb442eb8701de94908226f47533d3 166 SMART SM00988 1 65 3.1E-23 T 13-09-2016 IPR004029 UreE urease accessory, N-terminal THL1_RS25635 c44fb442eb8701de94908226f47533d3 166 SUPERFAMILY SSF69737 71 138 1.96E-21 T 13-09-2016 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 THL1_RS25635 c44fb442eb8701de94908226f47533d3 166 Pfam PF02814 UreE urease accessory protein, N-terminal domain 6 65 7.6E-20 T 13-09-2016 IPR004029 UreE urease accessory, N-terminal THL1_RS25635 c44fb442eb8701de94908226f47533d3 166 PIRSF PIRSF036402 1 149 1.1E-49 T 13-09-2016 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 THL1_RS25635 c44fb442eb8701de94908226f47533d3 166 Pfam PF05194 UreE urease accessory protein, C-terminal domain 72 148 5.9E-27 T 13-09-2016 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 THL1_RS25635 c44fb442eb8701de94908226f47533d3 166 Gene3D G3DSA:3.30.70.790 72 143 2.6E-32 T 13-09-2016 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 THL1_RS25635 c44fb442eb8701de94908226f47533d3 166 SUPERFAMILY SSF69287 1 71 2.75E-17 T 13-09-2016 IPR004029 UreE urease accessory, N-terminal THL1_RS25635 c44fb442eb8701de94908226f47533d3 166 Hamap MF_00822 Urease accessory protein UreE [ureE]. 2 139 23.651 T 13-09-2016 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 THL1_RS25635 c44fb442eb8701de94908226f47533d3 166 Gene3D G3DSA:2.60.260.20 1 69 2.2E-15 T 13-09-2016 THL1_RS11345 7aa3f872838cad20a0e89d083410639d 118 Gene3D G3DSA:3.40.250.10 26 114 3.8E-25 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS11345 7aa3f872838cad20a0e89d083410639d 118 Pfam PF00581 Rhodanese-like domain 25 106 3.8E-11 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS11345 7aa3f872838cad20a0e89d083410639d 118 SUPERFAMILY SSF52821 20 111 1.96E-26 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS11345 7aa3f872838cad20a0e89d083410639d 118 SMART SM00450 21 117 2.0E-19 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS13210 d55e7125b8c54f41744cae4a531e41bf 362 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 172 287 1.4E-7 T 13-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain THL1_RS13210 d55e7125b8c54f41744cae4a531e41bf 362 PANTHER PTHR13789:SF244 170 298 8.1E-28 T 13-09-2016 THL1_RS13210 d55e7125b8c54f41744cae4a531e41bf 362 SUPERFAMILY SSF54593 18 329 1.88E-41 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS13210 d55e7125b8c54f41744cae4a531e41bf 362 PANTHER PTHR13789 170 298 8.1E-28 T 13-09-2016 THL1_RS13210 d55e7125b8c54f41744cae4a531e41bf 362 Gene3D G3DSA:3.10.180.10 172 326 1.6E-36 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS13210 d55e7125b8c54f41744cae4a531e41bf 362 Gene3D G3DSA:3.10.180.10 27 140 5.0E-18 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS27045 6dcb59eb2220ae7c873fac49df4db7cd 269 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 25 258 2.1E-49 T 13-09-2016 IPR003786 Protein FdhD GO:0016783 THL1_RS27045 6dcb59eb2220ae7c873fac49df4db7cd 269 PIRSF PIRSF015626 6 266 1.3E-68 T 13-09-2016 IPR003786 Protein FdhD GO:0016783 THL1_RS27045 6dcb59eb2220ae7c873fac49df4db7cd 269 PANTHER PTHR30592:SF1 26 261 3.2E-96 T 13-09-2016 THL1_RS27045 6dcb59eb2220ae7c873fac49df4db7cd 269 Gene3D G3DSA:3.10.20.10 29 114 1.1E-25 T 13-09-2016 THL1_RS27045 6dcb59eb2220ae7c873fac49df4db7cd 269 SUPERFAMILY SSF53927 16 260 1.26E-69 T 13-09-2016 IPR016193 Cytidine deaminase-like GO:0003824 THL1_RS27045 6dcb59eb2220ae7c873fac49df4db7cd 269 PANTHER PTHR30592 26 261 3.2E-96 T 13-09-2016 THL1_RS27045 6dcb59eb2220ae7c873fac49df4db7cd 269 Pfam PF02634 FdhD/NarQ family 27 260 8.2E-66 T 13-09-2016 IPR003786 Protein FdhD GO:0016783 THL1_RS27045 6dcb59eb2220ae7c873fac49df4db7cd 269 Gene3D G3DSA:3.40.140.10 130 260 3.4E-41 T 13-09-2016 THL1_RS11855 c85082465679748f8173d1b797bec035 860 Gene3D G3DSA:3.40.50.300 2 120 3.1E-6 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11855 c85082465679748f8173d1b797bec035 860 SUPERFAMILY SSF46894 793 858 1.8E-20 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS11855 c85082465679748f8173d1b797bec035 860 Pfam PF00196 Bacterial regulatory proteins, luxR family 798 850 1.1E-16 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS11855 c85082465679748f8173d1b797bec035 860 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 828 840 1.3E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS11855 c85082465679748f8173d1b797bec035 860 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 812 828 1.3E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS11855 c85082465679748f8173d1b797bec035 860 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 798 812 1.3E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS11855 c85082465679748f8173d1b797bec035 860 Gene3D G3DSA:1.25.40.10 422 773 5.7E-16 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS11855 c85082465679748f8173d1b797bec035 860 SUPERFAMILY SSF52540 87 188 6.3E-9 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11855 c85082465679748f8173d1b797bec035 860 SUPERFAMILY SSF52540 1 57 6.3E-9 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11855 c85082465679748f8173d1b797bec035 860 ProSitePatterns PS00622 LuxR-type HTH domain signature. 812 839 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS11855 c85082465679748f8173d1b797bec035 860 SMART SM00421 795 852 4.8E-25 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS11855 c85082465679748f8173d1b797bec035 860 Gene3D G3DSA:1.10.10.10 791 858 4.6E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS25745 92b436353bad188fe7f9f68b42f6ab52 311 PANTHER PTHR33490:SF6 1 306 6.3E-85 T 13-09-2016 THL1_RS25745 92b436353bad188fe7f9f68b42f6ab52 311 SMART SM00460 192 262 6.6E-25 T 13-09-2016 IPR002931 Transglutaminase-like THL1_RS25745 92b436353bad188fe7f9f68b42f6ab52 311 SUPERFAMILY SSF54001 72 287 1.86E-46 T 13-09-2016 THL1_RS25745 92b436353bad188fe7f9f68b42f6ab52 311 Pfam PF01841 Transglutaminase-like superfamily 163 260 5.3E-23 T 13-09-2016 IPR002931 Transglutaminase-like THL1_RS25745 92b436353bad188fe7f9f68b42f6ab52 311 Gene3D G3DSA:3.90.260.10 196 267 4.4E-14 T 13-09-2016 IPR002931 Transglutaminase-like THL1_RS25745 92b436353bad188fe7f9f68b42f6ab52 311 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 16 95 1.6E-23 T 13-09-2016 IPR013589 Bacterial transglutaminase-like, N-terminal THL1_RS25745 92b436353bad188fe7f9f68b42f6ab52 311 PANTHER PTHR33490 1 306 6.3E-85 T 13-09-2016 THL1_RS07575 dea5cb3f8efa2567f081932a13b583f4 322 PANTHER PTHR30514:SF0 1 320 1.2E-76 T 13-09-2016 THL1_RS07575 dea5cb3f8efa2567f081932a13b583f4 322 Pfam PF02685 Glucokinase 5 315 1.4E-107 T 13-09-2016 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 THL1_RS07575 dea5cb3f8efa2567f081932a13b583f4 322 Hamap MF_00524 Glucokinase [glk]. 1 316 35.204 T 13-09-2016 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 THL1_RS07575 dea5cb3f8efa2567f081932a13b583f4 322 TIGRFAM TIGR00749 glk: glucokinase 5 310 2.6E-80 T 13-09-2016 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 THL1_RS07575 dea5cb3f8efa2567f081932a13b583f4 322 Gene3D G3DSA:3.40.367.20 100 299 1.8E-69 T 13-09-2016 THL1_RS07575 dea5cb3f8efa2567f081932a13b583f4 322 SUPERFAMILY SSF53067 4 316 1.25E-55 T 13-09-2016 THL1_RS07575 dea5cb3f8efa2567f081932a13b583f4 322 PANTHER PTHR30514 1 320 1.2E-76 T 13-09-2016 THL1_RS22125 57f6040742b35f32a93d622411222c17 201 PANTHER PTHR33796 2 201 2.2E-78 T 13-09-2016 THL1_RS22125 57f6040742b35f32a93d622411222c17 201 SMART SM00278 73 92 0.72 T 13-09-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THL1_RS22125 57f6040742b35f32a93d622411222c17 201 SMART SM00278 108 127 0.017 T 13-09-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THL1_RS22125 57f6040742b35f32a93d622411222c17 201 SUPERFAMILY SSF46929 156 200 3.01E-10 T 13-09-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 THL1_RS22125 57f6040742b35f32a93d622411222c17 201 Pfam PF14520 Helix-hairpin-helix domain 72 130 4.9E-18 T 13-09-2016 THL1_RS22125 57f6040742b35f32a93d622411222c17 201 SUPERFAMILY SSF50249 2 63 4.85E-18 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS22125 57f6040742b35f32a93d622411222c17 201 Gene3D G3DSA:2.40.50.140 2 64 8.0E-28 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS22125 57f6040742b35f32a93d622411222c17 201 Gene3D G3DSA:1.10.150.20 68 141 3.0E-30 T 13-09-2016 THL1_RS22125 57f6040742b35f32a93d622411222c17 201 SUPERFAMILY SSF47781 66 137 2.22E-22 T 13-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 THL1_RS22125 57f6040742b35f32a93d622411222c17 201 Gene3D G3DSA:1.10.8.10 155 200 7.6E-20 T 13-09-2016 THL1_RS22125 57f6040742b35f32a93d622411222c17 201 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 201 31.381 T 13-09-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 THL1_RS22125 57f6040742b35f32a93d622411222c17 201 Pfam PF07499 RuvA, C-terminal domain 157 200 2.5E-14 T 13-09-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 THL1_RS22125 57f6040742b35f32a93d622411222c17 201 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 199 4.9E-60 T 13-09-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 THL1_RS22125 57f6040742b35f32a93d622411222c17 201 Pfam PF01330 RuvA N terminal domain 2 62 2.8E-21 T 13-09-2016 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 THL1_RS07520 62834077cb3658ddd1ba78986739f332 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 20 34 9.3E-13 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07520 62834077cb3658ddd1ba78986739f332 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 34 50 9.3E-13 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07520 62834077cb3658ddd1ba78986739f332 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 50 62 9.3E-13 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07520 62834077cb3658ddd1ba78986739f332 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 19 72 1.3E-18 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07520 62834077cb3658ddd1ba78986739f332 221 PANTHER PTHR26402 18 71 6.2E-15 T 13-09-2016 THL1_RS07520 62834077cb3658ddd1ba78986739f332 221 SUPERFAMILY SSF55785 108 216 9.42E-12 T 13-09-2016 IPR000014 PAS domain THL1_RS07520 62834077cb3658ddd1ba78986739f332 221 Gene3D G3DSA:3.30.450.20 108 216 1.6E-11 T 13-09-2016 THL1_RS07520 62834077cb3658ddd1ba78986739f332 221 SUPERFAMILY SSF46894 10 78 1.7E-18 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS07520 62834077cb3658ddd1ba78986739f332 221 SMART SM00421 17 74 3.1E-18 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07520 62834077cb3658ddd1ba78986739f332 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 34 61 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07520 62834077cb3658ddd1ba78986739f332 221 Gene3D G3DSA:1.10.10.10 15 78 5.3E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07520 62834077cb3658ddd1ba78986739f332 221 PANTHER PTHR26402:SF555 18 71 6.2E-15 T 13-09-2016 THL1_RS07520 62834077cb3658ddd1ba78986739f332 221 Pfam PF08447 PAS fold 129 215 1.2E-12 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS25235 506ccd7979d3cfc2848d1d9efdf3e660 80 SUPERFAMILY SSF47413 7 68 1.31E-9 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS25235 506ccd7979d3cfc2848d1d9efdf3e660 80 Pfam PF13560 Helix-turn-helix domain 10 67 1.1E-11 T 13-09-2016 THL1_RS25235 506ccd7979d3cfc2848d1d9efdf3e660 80 Gene3D G3DSA:1.10.260.40 8 67 4.9E-9 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS07720 6b0b35150bc19290839ca18554b6a056 163 Gene3D G3DSA:3.10.450.50 1 156 8.2E-52 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS07720 6b0b35150bc19290839ca18554b6a056 163 PANTHER PTHR41534 1 163 9.8E-80 T 13-09-2016 THL1_RS07720 6b0b35150bc19290839ca18554b6a056 163 PANTHER PTHR41534:SF1 1 163 9.8E-80 T 13-09-2016 THL1_RS07720 6b0b35150bc19290839ca18554b6a056 163 Pfam PF00866 Ring hydroxylating beta subunit 18 156 4.2E-47 T 13-09-2016 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 THL1_RS07720 6b0b35150bc19290839ca18554b6a056 163 TIGRFAM TIGR03231 anthran_1_2_B: anthranilate 1,2-dioxygenase, small subunit 9 163 7.2E-89 T 13-09-2016 IPR017640 Anthranilate 1,2-dioxygenase, small subunit KEGG: 00627+1.14.12.1|MetaCyc: PWY-2421|MetaCyc: PWY-5648|MetaCyc: PWY-6079|UniPathway: UPA01016 THL1_RS07720 6b0b35150bc19290839ca18554b6a056 163 SUPERFAMILY SSF54427 1 163 7.32E-52 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS08660 76e3f0fca15180a83a6c57cd4f95c106 298 PANTHER PTHR22911 1 296 2.7E-118 T 13-09-2016 THL1_RS08660 76e3f0fca15180a83a6c57cd4f95c106 298 SUPERFAMILY SSF103481 40 146 5.75E-6 T 13-09-2016 THL1_RS08660 76e3f0fca15180a83a6c57cd4f95c106 298 PANTHER PTHR22911:SF57 1 296 2.7E-118 T 13-09-2016 THL1_RS08660 76e3f0fca15180a83a6c57cd4f95c106 298 SUPERFAMILY SSF103481 188 286 1.83E-7 T 13-09-2016 THL1_RS08660 76e3f0fca15180a83a6c57cd4f95c106 298 TIGRFAM TIGR00688 rarD: protein RarD 6 259 1.0E-55 T 13-09-2016 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 THL1_RS00410 0c608c965619e95e72b3f5723a8249af 259 SUPERFAMILY SSF55846 22 175 2.75E-49 T 13-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 THL1_RS00410 0c608c965619e95e72b3f5723a8249af 259 SUPERFAMILY SSF47090 186 254 2.55E-18 T 13-09-2016 IPR002477 Peptidoglycan binding-like THL1_RS00410 0c608c965619e95e72b3f5723a8249af 259 Gene3D G3DSA:3.40.80.10 25 181 2.8E-50 T 13-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 THL1_RS00410 0c608c965619e95e72b3f5723a8249af 259 Pfam PF01471 Putative peptidoglycan binding domain 199 251 8.8E-9 T 13-09-2016 IPR002477 Peptidoglycan binding-like THL1_RS00410 0c608c965619e95e72b3f5723a8249af 259 PANTHER PTHR30417 34 255 1.8E-72 T 13-09-2016 THL1_RS00410 0c608c965619e95e72b3f5723a8249af 259 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 33 164 9.9E-21 T 13-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 THL1_RS00410 0c608c965619e95e72b3f5723a8249af 259 Gene3D G3DSA:1.10.101.10 198 251 1.2E-4 T 13-09-2016 IPR002477 Peptidoglycan binding-like THL1_RS00410 0c608c965619e95e72b3f5723a8249af 259 SMART SM00644 23 163 2.4E-30 T 13-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 PANTHER PTHR10799:SF774 563 801 2.8E-80 T 13-09-2016 THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 Gene3D G3DSA:3.30.450.20 400 513 1.2E-25 T 13-09-2016 THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 Gene3D G3DSA:3.20.20.450 703 955 7.3E-103 T 13-09-2016 IPR001633 EAL domain THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 SUPERFAMILY SSF55785 410 517 4.83E-25 T 13-09-2016 IPR000014 PAS domain THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 SMART SM00052 701 947 1.3E-118 T 13-09-2016 IPR001633 EAL domain THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 Pfam PF08447 PAS fold 307 390 4.0E-21 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 Pfam PF00990 Diguanylate cyclase, GGDEF domain 531 686 5.1E-43 T 13-09-2016 IPR000160 GGDEF domain THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 SUPERFAMILY SSF141868 706 954 2.48E-91 T 13-09-2016 IPR001633 EAL domain THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 PANTHER PTHR10799 563 801 2.8E-80 T 13-09-2016 THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 PANTHER PTHR10799 384 536 2.8E-80 T 13-09-2016 THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 Pfam PF00563 EAL domain 707 942 1.8E-73 T 13-09-2016 IPR001633 EAL domain THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 529 689 8.0E-34 T 13-09-2016 IPR000160 GGDEF domain THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 Gene3D G3DSA:3.30.70.270 532 696 1.9E-49 T 13-09-2016 THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 Gene3D G3DSA:3.30.450.20 258 399 8.0E-29 T 13-09-2016 THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 Pfam PF13426 PAS domain 416 517 4.1E-15 T 13-09-2016 IPR000014 PAS domain THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 SUPERFAMILY SSF55785 286 398 2.27E-17 T 13-09-2016 IPR000014 PAS domain THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 SMART SM00091 405 471 1.1E-9 T 13-09-2016 IPR000014 PAS domain THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 SMART SM00091 280 347 48.0 T 13-09-2016 IPR000014 PAS domain THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 277 402 8.9E-10 T 13-09-2016 IPR000014 PAS domain THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 402 526 1.0E-19 T 13-09-2016 IPR000014 PAS domain THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 PANTHER PTHR10799:SF774 384 536 2.8E-80 T 13-09-2016 THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 SMART SM00267 519 691 5.3E-55 T 13-09-2016 IPR000160 GGDEF domain THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 SMART SM00086 354 397 2.8E-9 T 13-09-2016 IPR001610 PAC motif THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 SMART SM00086 477 519 5.9E-4 T 13-09-2016 IPR001610 PAC motif THL1_RS28250 fb731e3dd2125677ee9e532a92e3f150 961 SUPERFAMILY SSF55073 535 693 2.43E-43 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS21575 45e726f5f8adf314f583e8ec9929870d 348 SUPERFAMILY SSF51556 3 343 6.01E-147 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS21575 45e726f5f8adf314f583e8ec9929870d 348 PANTHER PTHR11647:SF59 1 317 3.8E-168 T 13-09-2016 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS21575 45e726f5f8adf314f583e8ec9929870d 348 Hamap MF_00219 Dihydroorotase [pyrC]. 3 344 44.602 T 13-09-2016 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS21575 45e726f5f8adf314f583e8ec9929870d 348 PANTHER PTHR11647 1 317 3.8E-168 T 13-09-2016 THL1_RS21575 45e726f5f8adf314f583e8ec9929870d 348 Pfam PF01979 Amidohydrolase family 12 310 6.4E-15 T 13-09-2016 IPR006680 Amidohydrolase-related GO:0016787 THL1_RS21575 45e726f5f8adf314f583e8ec9929870d 348 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 5 343 4.3E-141 T 13-09-2016 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS21575 45e726f5f8adf314f583e8ec9929870d 348 ProSitePatterns PS00483 Dihydroorotase signature 2. 246 257 - T 13-09-2016 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS21575 45e726f5f8adf314f583e8ec9929870d 348 ProSitePatterns PS00482 Dihydroorotase signature 1. 12 20 - T 13-09-2016 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS21575 45e726f5f8adf314f583e8ec9929870d 348 Gene3D G3DSA:3.20.20.140 2 343 3.0E-136 T 13-09-2016 THL1_RS21575 45e726f5f8adf314f583e8ec9929870d 348 PIRSF PIRSF001237 1 346 2.3E-140 T 13-09-2016 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS24730 e185dec4a87fffda8b31f133ed2654a2 459 Gene3D G3DSA:3.40.190.10 375 439 5.5E-4 T 13-09-2016 THL1_RS24730 e185dec4a87fffda8b31f133ed2654a2 459 Pfam PF07012 Curlin associated repeat 338 369 9.9E-7 T 13-09-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 THL1_RS12805 e7ac0d9daefeb011d980a3870509c3b9 279 Pfam PF05114 Protein of unknown function (DUF692) 8 269 1.6E-108 T 13-09-2016 IPR007801 Uncharacterised protein family UPF0276 THL1_RS12805 e7ac0d9daefeb011d980a3870509c3b9 279 PANTHER PTHR42194:SF1 3 276 5.6E-78 T 13-09-2016 THL1_RS12805 e7ac0d9daefeb011d980a3870509c3b9 279 Gene3D G3DSA:3.20.20.150 7 271 3.4E-102 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS12805 e7ac0d9daefeb011d980a3870509c3b9 279 PANTHER PTHR42194 3 276 5.6E-78 T 13-09-2016 THL1_RS12805 e7ac0d9daefeb011d980a3870509c3b9 279 Hamap MF_00697 UPF0276 protein . 9 277 44.964 T 13-09-2016 IPR007801 Uncharacterised protein family UPF0276 THL1_RS05435 5ab36df76f2012fa48a40e48ff568d1a 437 PRINTS PR00083 Histidinol dehydrogenase signature 258 277 2.9E-88 T 13-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 THL1_RS05435 5ab36df76f2012fa48a40e48ff568d1a 437 PRINTS PR00083 Histidinol dehydrogenase signature 207 232 2.9E-88 T 13-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 THL1_RS05435 5ab36df76f2012fa48a40e48ff568d1a 437 PRINTS PR00083 Histidinol dehydrogenase signature 236 257 2.9E-88 T 13-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 THL1_RS05435 5ab36df76f2012fa48a40e48ff568d1a 437 PRINTS PR00083 Histidinol dehydrogenase signature 327 352 2.9E-88 T 13-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 THL1_RS05435 5ab36df76f2012fa48a40e48ff568d1a 437 PRINTS PR00083 Histidinol dehydrogenase signature 177 203 2.9E-88 T 13-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 THL1_RS05435 5ab36df76f2012fa48a40e48ff568d1a 437 PRINTS PR00083 Histidinol dehydrogenase signature 39 63 2.9E-88 T 13-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 THL1_RS05435 5ab36df76f2012fa48a40e48ff568d1a 437 PRINTS PR00083 Histidinol dehydrogenase signature 368 386 2.9E-88 T 13-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 THL1_RS05435 5ab36df76f2012fa48a40e48ff568d1a 437 PRINTS PR00083 Histidinol dehydrogenase signature 143 169 2.9E-88 T 13-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 THL1_RS05435 5ab36df76f2012fa48a40e48ff568d1a 437 PANTHER PTHR21256 5 437 1.0E-206 T 13-09-2016 THL1_RS05435 5ab36df76f2012fa48a40e48ff568d1a 437 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 39 433 4.5E-163 T 13-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 THL1_RS05435 5ab36df76f2012fa48a40e48ff568d1a 437 PIRSF PIRSF000099 6 436 1.3E-161 T 13-09-2016 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 THL1_RS05435 5ab36df76f2012fa48a40e48ff568d1a 437 SUPERFAMILY SSF53720 27 434 9.42E-87 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS05435 5ab36df76f2012fa48a40e48ff568d1a 437 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 11 434 41.24 T 13-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 THL1_RS05435 5ab36df76f2012fa48a40e48ff568d1a 437 Pfam PF00815 Histidinol dehydrogenase 30 433 7.1E-171 T 13-09-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 THL1_RS05435 5ab36df76f2012fa48a40e48ff568d1a 437 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 236 268 - T 13-09-2016 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 THL1_RS05435 5ab36df76f2012fa48a40e48ff568d1a 437 Gene3D G3DSA:3.40.50.1980 33 246 4.1E-81 T 13-09-2016 THL1_RS10075 80316964390d038ad185ab365d6bd245 90 Pfam PF10983 Protein of unknown function (DUF2793) 3 81 3.1E-17 T 13-09-2016 IPR021251 Protein of unknown function DUF2793 THL1_RS14740 a7c57872f45d28198bf83a2d6613fd2c 128 SUPERFAMILY SSF55298 6 122 1.73E-34 T 13-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THL1_RS14740 a7c57872f45d28198bf83a2d6613fd2c 128 Pfam PF01042 Endoribonuclease L-PSP 11 121 3.4E-27 T 13-09-2016 IPR006175 YjgF/YER057c/UK114 family THL1_RS14740 a7c57872f45d28198bf83a2d6613fd2c 128 Gene3D G3DSA:3.30.1330.40 12 120 4.0E-35 T 13-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THL1_RS14740 a7c57872f45d28198bf83a2d6613fd2c 128 PANTHER PTHR11803 13 124 1.1E-33 T 13-09-2016 IPR006175 YjgF/YER057c/UK114 family THL1_RS13055 c7eb67b2fc76c57bfa3d52f1cdd02f5d 422 Gene3D G3DSA:3.50.50.60 279 348 6.0E-32 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS13055 c7eb67b2fc76c57bfa3d52f1cdd02f5d 422 Gene3D G3DSA:3.50.50.60 34 145 6.0E-32 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS13055 c7eb67b2fc76c57bfa3d52f1cdd02f5d 422 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 34 144 8.5E-9 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS13055 c7eb67b2fc76c57bfa3d52f1cdd02f5d 422 SUPERFAMILY SSF51905 147 261 4.53E-21 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS13055 c7eb67b2fc76c57bfa3d52f1cdd02f5d 422 Gene3D G3DSA:3.50.50.60 148 277 1.8E-37 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS13055 c7eb67b2fc76c57bfa3d52f1cdd02f5d 422 PANTHER PTHR10632:SF10 27 361 4.2E-78 T 13-09-2016 THL1_RS13055 c7eb67b2fc76c57bfa3d52f1cdd02f5d 422 PANTHER PTHR10632 27 361 4.2E-78 T 13-09-2016 THL1_RS13055 c7eb67b2fc76c57bfa3d52f1cdd02f5d 422 SUPERFAMILY SSF51905 273 350 6.37E-22 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS13055 c7eb67b2fc76c57bfa3d52f1cdd02f5d 422 SUPERFAMILY SSF51905 34 139 6.37E-22 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS25955 66a9ac1bc18203118914cffad11c52e7 752 SUPERFAMILY SSF56719 35 487 5.89E-154 T 13-09-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 THL1_RS25955 66a9ac1bc18203118914cffad11c52e7 752 SMART SM00434 15 465 3.2E-229 T 13-09-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS25955 66a9ac1bc18203118914cffad11c52e7 752 PANTHER PTHR10169 1 527 0.0 T 13-09-2016 THL1_RS25955 66a9ac1bc18203118914cffad11c52e7 752 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 8 747 33.7 T 13-09-2016 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS25955 66a9ac1bc18203118914cffad11c52e7 752 Gene3D G3DSA:3.30.1360.40 242 335 4.6E-24 T 13-09-2016 IPR024946 Arginine repressor C-terminal-like domain THL1_RS25955 66a9ac1bc18203118914cffad11c52e7 752 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 602 641 0.0039 T 13-09-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THL1_RS25955 66a9ac1bc18203118914cffad11c52e7 752 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 649 688 7.5E-4 T 13-09-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THL1_RS25955 66a9ac1bc18203118914cffad11c52e7 752 PANTHER PTHR10169:SF30 1 527 0.0 T 13-09-2016 THL1_RS25955 66a9ac1bc18203118914cffad11c52e7 752 Gene3D G3DSA:3.90.199.10 337 401 3.4E-103 T 13-09-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 THL1_RS25955 66a9ac1bc18203118914cffad11c52e7 752 Gene3D G3DSA:3.90.199.10 34 241 3.4E-103 T 13-09-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 THL1_RS25955 66a9ac1bc18203118914cffad11c52e7 752 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 12 745 0.0 T 13-09-2016 THL1_RS25955 66a9ac1bc18203118914cffad11c52e7 752 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 36 472 8.0E-132 T 13-09-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS25955 66a9ac1bc18203118914cffad11c52e7 752 Gene3D G3DSA:2.120.10.90 500 740 5.4E-24 T 13-09-2016 THL1_RS25955 66a9ac1bc18203118914cffad11c52e7 752 SUPERFAMILY SSF101904 501 747 1.44E-51 T 13-09-2016 THL1_RS08720 574a69391320ee0d0eb3283c3c475dea 312 Gene3D G3DSA:3.40.190.10 92 190 6.2E-27 T 13-09-2016 THL1_RS08720 574a69391320ee0d0eb3283c3c475dea 312 Pfam PF03466 LysR substrate binding domain 87 298 8.8E-35 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS08720 574a69391320ee0d0eb3283c3c475dea 312 Gene3D G3DSA:1.10.10.10 1 84 4.1E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08720 574a69391320ee0d0eb3283c3c475dea 312 SUPERFAMILY SSF46785 2 85 3.43E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08720 574a69391320ee0d0eb3283c3c475dea 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 4.7E-17 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08720 574a69391320ee0d0eb3283c3c475dea 312 PANTHER PTHR30537 1 303 7.4E-78 T 13-09-2016 THL1_RS08720 574a69391320ee0d0eb3283c3c475dea 312 PANTHER PTHR30537:SF26 1 303 7.4E-78 T 13-09-2016 THL1_RS08720 574a69391320ee0d0eb3283c3c475dea 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 5.2E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08720 574a69391320ee0d0eb3283c3c475dea 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 5.2E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08720 574a69391320ee0d0eb3283c3c475dea 312 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 5.2E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08720 574a69391320ee0d0eb3283c3c475dea 312 SUPERFAMILY SSF53850 88 301 1.19E-35 T 13-09-2016 THL1_RS27400 b7e0af8f15c06c172d3b5f31ca7b9ef9 636 Pfam PF12848 ABC transporter 217 295 5.6E-27 T 13-09-2016 IPR032781 ABC-transporter extension domain THL1_RS27400 b7e0af8f15c06c172d3b5f31ca7b9ef9 636 SUPERFAMILY SSF52540 119 257 1.59E-45 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27400 b7e0af8f15c06c172d3b5f31ca7b9ef9 636 SUPERFAMILY SSF52540 2 92 1.59E-45 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27400 b7e0af8f15c06c172d3b5f31ca7b9ef9 636 SMART SM00382 26 223 1.6E-7 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS27400 b7e0af8f15c06c172d3b5f31ca7b9ef9 636 SMART SM00382 337 504 2.5E-14 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS27400 b7e0af8f15c06c172d3b5f31ca7b9ef9 636 Pfam PF00005 ABC transporter 328 459 6.2E-23 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS27400 b7e0af8f15c06c172d3b5f31ca7b9ef9 636 Pfam PF00005 ABC transporter 18 178 5.1E-22 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS27400 b7e0af8f15c06c172d3b5f31ca7b9ef9 636 PANTHER PTHR19211 1 554 0.0 T 13-09-2016 THL1_RS27400 b7e0af8f15c06c172d3b5f31ca7b9ef9 636 ProSitePatterns PS00211 ABC transporters family signature. 431 445 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS27400 b7e0af8f15c06c172d3b5f31ca7b9ef9 636 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS27400 b7e0af8f15c06c172d3b5f31ca7b9ef9 636 SUPERFAMILY SSF52540 297 517 2.39E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27400 b7e0af8f15c06c172d3b5f31ca7b9ef9 636 PANTHER PTHR19211:SF49 1 554 0.0 T 13-09-2016 THL1_RS27400 b7e0af8f15c06c172d3b5f31ca7b9ef9 636 Gene3D G3DSA:3.40.50.300 1 266 3.3E-46 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27400 b7e0af8f15c06c172d3b5f31ca7b9ef9 636 Gene3D G3DSA:3.40.50.300 311 516 5.4E-41 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18125 66bbf75c43d83d9f2a5b9efcffbc40d9 350 PANTHER PTHR30128:SF10 140 346 4.0E-63 T 13-09-2016 THL1_RS18125 66bbf75c43d83d9f2a5b9efcffbc40d9 350 Gene3D G3DSA:4.10.1080.10 201 242 2.7E-7 T 13-09-2016 IPR028974 TSP type-3 repeat GO:0005509 THL1_RS18125 66bbf75c43d83d9f2a5b9efcffbc40d9 350 PANTHER PTHR30128 140 346 4.0E-63 T 13-09-2016 THL1_RS18125 66bbf75c43d83d9f2a5b9efcffbc40d9 350 Gene3D G3DSA:3.30.1330.60 243 345 1.1E-40 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS18125 66bbf75c43d83d9f2a5b9efcffbc40d9 350 Pfam PF05736 OprF membrane domain 1 185 1.3E-83 T 13-09-2016 IPR008722 Outer membrane porin F, N-terminal THL1_RS18125 66bbf75c43d83d9f2a5b9efcffbc40d9 350 Gene3D G3DSA:2.40.160.20 39 198 5.5E-14 T 13-09-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 THL1_RS18125 66bbf75c43d83d9f2a5b9efcffbc40d9 350 SUPERFAMILY SSF56925 38 185 5.23E-16 T 13-09-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 THL1_RS18125 66bbf75c43d83d9f2a5b9efcffbc40d9 350 SUPERFAMILY SSF103647 199 231 3.92E-7 T 13-09-2016 IPR028974 TSP type-3 repeat GO:0005509 THL1_RS18125 66bbf75c43d83d9f2a5b9efcffbc40d9 350 SUPERFAMILY SSF103088 235 345 1.7E-38 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS18125 66bbf75c43d83d9f2a5b9efcffbc40d9 350 Pfam PF00691 OmpA family 244 339 2.9E-23 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS18125 66bbf75c43d83d9f2a5b9efcffbc40d9 350 PRINTS PR01021 OMPA domain signature 244 266 7.7E-18 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS18125 66bbf75c43d83d9f2a5b9efcffbc40d9 350 PRINTS PR01021 OMPA domain signature 289 305 7.7E-18 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS18125 66bbf75c43d83d9f2a5b9efcffbc40d9 350 PRINTS PR01021 OMPA domain signature 274 289 7.7E-18 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS18125 66bbf75c43d83d9f2a5b9efcffbc40d9 350 ProSitePatterns PS01068 OmpA-like domain. 276 321 - T 13-09-2016 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 THL1_RS05510 0b0db80977838acdc452876add30dfdb 332 SUPERFAMILY SSF46689 277 328 8.06E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS05510 0b0db80977838acdc452876add30dfdb 332 Gene3D G3DSA:1.10.10.60 232 277 4.2E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS05510 0b0db80977838acdc452876add30dfdb 332 Gene3D G3DSA:1.10.10.60 278 328 6.8E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS05510 0b0db80977838acdc452876add30dfdb 332 SMART SM00342 241 324 3.5E-24 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS05510 0b0db80977838acdc452876add30dfdb 332 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 278 320 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS05510 0b0db80977838acdc452876add30dfdb 332 Gene3D G3DSA:3.40.50.880 11 231 1.6E-38 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS05510 0b0db80977838acdc452876add30dfdb 332 SUPERFAMILY SSF52317 10 207 1.41E-35 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS05510 0b0db80977838acdc452876add30dfdb 332 PANTHER PTHR11019 121 332 7.6E-60 T 13-09-2016 THL1_RS05510 0b0db80977838acdc452876add30dfdb 332 PANTHER PTHR11019:SF61 121 332 7.6E-60 T 13-09-2016 THL1_RS05510 0b0db80977838acdc452876add30dfdb 332 SUPERFAMILY SSF46689 226 275 2.33E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS05510 0b0db80977838acdc452876add30dfdb 332 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 293 308 5.5E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS05510 0b0db80977838acdc452876add30dfdb 332 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 308 324 5.5E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS05510 0b0db80977838acdc452876add30dfdb 332 Pfam PF12833 Helix-turn-helix domain 248 326 4.2E-21 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS15360 1e872fec9497c700493241d9521e3bc1 689 SMART SM00267 252 423 1.8E-63 T 13-09-2016 IPR000160 GGDEF domain THL1_RS15360 1e872fec9497c700493241d9521e3bc1 689 PANTHER PTHR10799 148 534 1.4E-82 T 13-09-2016 THL1_RS15360 1e872fec9497c700493241d9521e3bc1 689 Gene3D G3DSA:3.20.20.450 436 682 1.7E-99 T 13-09-2016 IPR001633 EAL domain THL1_RS15360 1e872fec9497c700493241d9521e3bc1 689 Gene3D G3DSA:3.30.70.270 265 431 2.0E-57 T 13-09-2016 THL1_RS15360 1e872fec9497c700493241d9521e3bc1 689 Pfam PF00563 EAL domain 440 675 3.3E-73 T 13-09-2016 IPR001633 EAL domain THL1_RS15360 1e872fec9497c700493241d9521e3bc1 689 SUPERFAMILY SSF55073 268 425 6.43E-49 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS15360 1e872fec9497c700493241d9521e3bc1 689 Pfam PF03707 Bacterial signalling protein N terminal repeat 52 108 1.3E-22 T 13-09-2016 IPR005330 MHYT domain THL1_RS15360 1e872fec9497c700493241d9521e3bc1 689 Pfam PF03707 Bacterial signalling protein N terminal repeat 182 246 3.8E-15 T 13-09-2016 IPR005330 MHYT domain THL1_RS15360 1e872fec9497c700493241d9521e3bc1 689 Pfam PF03707 Bacterial signalling protein N terminal repeat 115 167 6.6E-16 T 13-09-2016 IPR005330 MHYT domain THL1_RS15360 1e872fec9497c700493241d9521e3bc1 689 PANTHER PTHR10799:SF774 148 534 1.4E-82 T 13-09-2016 THL1_RS15360 1e872fec9497c700493241d9521e3bc1 689 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 259 421 1.3E-43 T 13-09-2016 IPR000160 GGDEF domain THL1_RS15360 1e872fec9497c700493241d9521e3bc1 689 Pfam PF00990 Diguanylate cyclase, GGDEF domain 263 418 7.0E-45 T 13-09-2016 IPR000160 GGDEF domain THL1_RS15360 1e872fec9497c700493241d9521e3bc1 689 SUPERFAMILY SSF141868 439 682 1.7E-90 T 13-09-2016 IPR001633 EAL domain THL1_RS15360 1e872fec9497c700493241d9521e3bc1 689 SMART SM00052 433 680 3.4E-120 T 13-09-2016 IPR001633 EAL domain THL1_RS03695 f34974164fb682a07d7e1a42dbe96966 549 PANTHER PTHR21091:SF9 29 47 9.3E-39 T 13-09-2016 THL1_RS03695 f34974164fb682a07d7e1a42dbe96966 549 PANTHER PTHR21091 29 47 9.3E-39 T 13-09-2016 THL1_RS03695 f34974164fb682a07d7e1a42dbe96966 549 Gene3D G3DSA:3.40.1010.10 300 416 1.9E-28 T 13-09-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 THL1_RS03695 f34974164fb682a07d7e1a42dbe96966 549 Gene3D G3DSA:3.30.950.10 417 530 3.5E-9 T 13-09-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 THL1_RS03695 f34974164fb682a07d7e1a42dbe96966 549 Pfam PF11760 Cobalamin synthesis G N-terminal 49 128 1.3E-25 T 13-09-2016 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377|UniPathway: UPA00148 THL1_RS03695 f34974164fb682a07d7e1a42dbe96966 549 PANTHER PTHR21091:SF9 268 468 9.3E-39 T 13-09-2016 THL1_RS03695 f34974164fb682a07d7e1a42dbe96966 549 PANTHER PTHR21091 268 468 9.3E-39 T 13-09-2016 THL1_RS03695 f34974164fb682a07d7e1a42dbe96966 549 SUPERFAMILY SSF159672 3 209 7.59E-44 T 13-09-2016 THL1_RS03695 f34974164fb682a07d7e1a42dbe96966 549 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 301 512 8.2E-30 T 13-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 THL1_RS03695 f34974164fb682a07d7e1a42dbe96966 549 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 302 548 6.7E-87 T 13-09-2016 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 THL1_RS03695 f34974164fb682a07d7e1a42dbe96966 549 SUPERFAMILY SSF53790 296 545 4.45E-50 T 13-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 THL1_RS26145 52764fa5025f6d8bb490937fbddad206 485 Gene3D G3DSA:1.10.510.10 401 445 8.5E-6 T 13-09-2016 THL1_RS26145 52764fa5025f6d8bb490937fbddad206 485 SUPERFAMILY SSF56112 44 171 1.38E-10 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS26145 52764fa5025f6d8bb490937fbddad206 485 SUPERFAMILY SSF56112 285 470 5.05E-16 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS26145 52764fa5025f6d8bb490937fbddad206 485 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 306 447 1.4E-8 T 13-09-2016 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 468 590 3.5E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 Pfam PF02743 Cache domain 142 358 5.9E-15 T 13-09-2016 IPR033479 Double Cache domain 1 THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 Pfam PF00072 Response regulator receiver domain 854 962 1.8E-16 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 SUPERFAMILY SSF52172 852 969 1.71E-24 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 Pfam PF00512 His Kinase A (phospho-acceptor) domain 603 671 4.1E-16 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 SMART SM00388 603 672 1.5E-18 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 720 827 2.0E-20 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 SUPERFAMILY SSF55785 472 585 3.56E-13 T 13-09-2016 IPR000014 PAS domain THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 Gene3D G3DSA:3.40.50.2300 847 970 2.0E-25 T 13-09-2016 THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 Gene3D G3DSA:3.30.450.20 213 373 2.3E-22 T 13-09-2016 THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 Pfam PF08447 PAS fold 490 577 5.1E-13 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 SUPERFAMILY SSF47384 588 672 1.69E-18 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 PANTHER PTHR24423 451 963 3.2E-112 T 13-09-2016 THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 SMART SM00448 852 964 4.5E-21 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 PRINTS PR00344 Bacterial sensor protein C-terminal signature 790 808 1.3E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 PRINTS PR00344 Bacterial sensor protein C-terminal signature 756 770 1.3E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 PRINTS PR00344 Bacterial sensor protein C-terminal signature 814 827 1.3E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 PRINTS PR00344 Bacterial sensor protein C-terminal signature 774 784 1.3E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 Gene3D G3DSA:3.30.565.10 673 828 8.0E-40 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 Gene3D G3DSA:3.30.450.20 458 597 5.5E-26 T 13-09-2016 THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 SUPERFAMILY SSF55874 661 828 1.31E-40 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 SMART SM00387 719 830 4.7E-27 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24555 483e8a8fb945e3e12fe7ceeeee427137 972 Gene3D G3DSA:1.10.287.130 598 667 2.0E-17 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS01745 d762cfaccfec48b56209a63bc3ef86e9 314 SUPERFAMILY SSF53850 23 300 5.58E-79 T 13-09-2016 THL1_RS01745 d762cfaccfec48b56209a63bc3ef86e9 314 Gene3D G3DSA:3.40.190.100 118 235 7.4E-22 T 13-09-2016 THL1_RS01745 d762cfaccfec48b56209a63bc3ef86e9 314 TIGRFAM TIGR03414 ABC_choline_bnd: choline ABC transporter, periplasmic binding protein 23 312 2.3E-139 T 13-09-2016 IPR017783 ABC transporter, choline, substrate-binding protein GO:0015871|GO:0033265|GO:0042597 THL1_RS01745 d762cfaccfec48b56209a63bc3ef86e9 314 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 30 283 3.7E-51 T 13-09-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 THL1_RS01745 d762cfaccfec48b56209a63bc3ef86e9 314 PANTHER PTHR30177:SF6 7 288 8.8E-109 T 13-09-2016 THL1_RS01745 d762cfaccfec48b56209a63bc3ef86e9 314 PANTHER PTHR30177 7 288 8.8E-109 T 13-09-2016 THL1_RS01745 d762cfaccfec48b56209a63bc3ef86e9 314 Gene3D G3DSA:3.40.190.10 24 113 2.2E-31 T 13-09-2016 THL1_RS01745 d762cfaccfec48b56209a63bc3ef86e9 314 Gene3D G3DSA:3.40.190.10 236 300 2.2E-31 T 13-09-2016 THL1_RS10640 b88b707760b7c1996b0f25d803312537 203 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 116 126 5.4E-12 T 13-09-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 THL1_RS10640 b88b707760b7c1996b0f25d803312537 203 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 127 138 5.4E-12 T 13-09-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 THL1_RS10640 b88b707760b7c1996b0f25d803312537 203 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 155 167 5.4E-12 T 13-09-2016 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 THL1_RS10640 b88b707760b7c1996b0f25d803312537 203 SUPERFAMILY SSF46785 3 70 9.28E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS10640 b88b707760b7c1996b0f25d803312537 203 Pfam PF01726 LexA DNA binding domain 1 65 2.3E-30 T 13-09-2016 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 THL1_RS10640 b88b707760b7c1996b0f25d803312537 203 Hamap MF_00015 LexA repressor [lexA]. 3 203 31.62 T 13-09-2016 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 THL1_RS10640 b88b707760b7c1996b0f25d803312537 203 Pfam PF00717 Peptidase S24-like 119 185 2.1E-16 T 13-09-2016 IPR019759 Peptidase S24/S26A/S26B THL1_RS10640 b88b707760b7c1996b0f25d803312537 203 Gene3D G3DSA:1.10.10.10 1 69 8.7E-29 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS10640 b88b707760b7c1996b0f25d803312537 203 Gene3D G3DSA:2.10.109.10 81 203 2.5E-45 T 13-09-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain THL1_RS10640 b88b707760b7c1996b0f25d803312537 203 PANTHER PTHR33516:SF2 1 203 4.8E-98 T 13-09-2016 THL1_RS10640 b88b707760b7c1996b0f25d803312537 203 PANTHER PTHR33516 1 203 4.8E-98 T 13-09-2016 THL1_RS10640 b88b707760b7c1996b0f25d803312537 203 SUPERFAMILY SSF51306 81 202 2.35E-37 T 13-09-2016 IPR015927 Peptidase S24/S26A/S26B/S26C THL1_RS10640 b88b707760b7c1996b0f25d803312537 203 TIGRFAM TIGR00498 lexA: repressor LexA 1 203 1.0E-74 T 13-09-2016 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 THL1_RS24085 ad204e1f7740c328c8afce5ca59ad255 516 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 201 214 - T 13-09-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 THL1_RS24085 ad204e1f7740c328c8afce5ca59ad255 516 SMART SM00917 372 503 2.4E-40 T 13-09-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 THL1_RS24085 ad204e1f7740c328c8afce5ca59ad255 516 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 14 30 - T 13-09-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 THL1_RS24085 ad204e1f7740c328c8afce5ca59ad255 516 PANTHER PTHR10277 1 511 8.7E-259 T 13-09-2016 THL1_RS24085 ad204e1f7740c328c8afce5ca59ad255 516 Gene3D G3DSA:3.20.20.70 3 349 2.9E-152 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS24085 ad204e1f7740c328c8afce5ca59ad255 516 SUPERFAMILY SSF51569 3 293 7.33E-105 T 13-09-2016 THL1_RS24085 ad204e1f7740c328c8afce5ca59ad255 516 SUPERFAMILY SSF110921 393 502 7.85E-26 T 13-09-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 THL1_RS24085 ad204e1f7740c328c8afce5ca59ad255 516 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 6 500 9.1E-225 T 13-09-2016 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 THL1_RS24085 ad204e1f7740c328c8afce5ca59ad255 516 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 4 512 44.255 T 13-09-2016 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 THL1_RS24085 ad204e1f7740c328c8afce5ca59ad255 516 Pfam PF08502 LeuA allosteric (dimerisation) domain 372 502 4.3E-37 T 13-09-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 THL1_RS24085 ad204e1f7740c328c8afce5ca59ad255 516 Pfam PF00682 HMGL-like 6 275 3.2E-100 T 13-09-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 THL1_RS24085 ad204e1f7740c328c8afce5ca59ad255 516 PANTHER PTHR10277:SF9 1 511 8.7E-259 T 13-09-2016 THL1_RS20170 2ed1f248fc69e74a12a3450349ef2550 235 Pfam PF00117 Glutamine amidotransferase class-I 35 211 6.4E-9 T 13-09-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 THL1_RS20170 2ed1f248fc69e74a12a3450349ef2550 235 Gene3D G3DSA:3.40.50.880 5 231 6.2E-41 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS20170 2ed1f248fc69e74a12a3450349ef2550 235 SUPERFAMILY SSF52317 6 231 2.5E-42 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS20170 2ed1f248fc69e74a12a3450349ef2550 235 PANTHER PTHR11550 28 211 2.1E-38 T 13-09-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 THL1_RS02660 1e2b52cd31e89358a7f83f9ed996be05 343 PANTHER PTHR30222:SF2 5 343 9.7E-172 T 13-09-2016 THL1_RS02660 1e2b52cd31e89358a7f83f9ed996be05 343 PANTHER PTHR30222 5 343 9.7E-172 T 13-09-2016 THL1_RS02660 1e2b52cd31e89358a7f83f9ed996be05 343 Pfam PF13416 Bacterial extracellular solute-binding protein 44 297 2.2E-46 T 13-09-2016 THL1_RS02660 1e2b52cd31e89358a7f83f9ed996be05 343 Gene3D G3DSA:3.40.190.10 24 139 1.6E-7 T 13-09-2016 THL1_RS02660 1e2b52cd31e89358a7f83f9ed996be05 343 SUPERFAMILY SSF53850 25 340 2.93E-66 T 13-09-2016 THL1_RS02660 1e2b52cd31e89358a7f83f9ed996be05 343 Gene3D G3DSA:3.40.190.10 140 283 1.0E-35 T 13-09-2016 THL1_RS21735 80c2d3f03376ba0b376ae7478be6060d 447 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 344 368 4.6E-54 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS21735 80c2d3f03376ba0b376ae7478be6060d 447 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 35 58 4.6E-54 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS21735 80c2d3f03376ba0b376ae7478be6060d 447 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 411 426 4.6E-54 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS21735 80c2d3f03376ba0b376ae7478be6060d 447 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 368 391 4.6E-54 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS21735 80c2d3f03376ba0b376ae7478be6060d 447 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 77 97 4.6E-54 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS21735 80c2d3f03376ba0b376ae7478be6060d 447 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 311 332 4.6E-54 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS21735 80c2d3f03376ba0b376ae7478be6060d 447 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 426 446 4.6E-54 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS21735 80c2d3f03376ba0b376ae7478be6060d 447 PANTHER PTHR30386:SF3 19 120 1.9E-124 T 13-09-2016 THL1_RS21735 80c2d3f03376ba0b376ae7478be6060d 447 PANTHER PTHR30386 158 447 1.9E-124 T 13-09-2016 THL1_RS21735 80c2d3f03376ba0b376ae7478be6060d 447 PANTHER PTHR30386:SF3 158 447 1.9E-124 T 13-09-2016 THL1_RS21735 80c2d3f03376ba0b376ae7478be6060d 447 Pfam PF00529 HlyD membrane-fusion protein of T1SS 37 402 9.6E-15 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS21735 80c2d3f03376ba0b376ae7478be6060d 447 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 25 447 6.5E-115 T 13-09-2016 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 THL1_RS21735 80c2d3f03376ba0b376ae7478be6060d 447 ProSitePatterns PS00543 HlyD family secretion proteins signature. 411 433 - T 13-09-2016 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 THL1_RS21735 80c2d3f03376ba0b376ae7478be6060d 447 PANTHER PTHR30386 19 120 1.9E-124 T 13-09-2016 THL1_RS21735 80c2d3f03376ba0b376ae7478be6060d 447 Gene3D G3DSA:2.40.50.100 296 330 8.8E-16 T 13-09-2016 THL1_RS21735 80c2d3f03376ba0b376ae7478be6060d 447 Gene3D G3DSA:2.40.50.100 68 99 8.8E-16 T 13-09-2016 THL1_RS21750 368d9abec10586250cff09ae21419f72 380 SUPERFAMILY SSF111369 49 283 2.09E-95 T 13-09-2016 THL1_RS21750 368d9abec10586250cff09ae21419f72 380 Pfam PF00529 HlyD membrane-fusion protein of T1SS 38 345 5.2E-11 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS21750 368d9abec10586250cff09ae21419f72 380 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 62 278 2.5E-18 T 13-09-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THL1_RS21750 368d9abec10586250cff09ae21419f72 380 PANTHER PTHR30158 1 375 1.7E-163 T 13-09-2016 THL1_RS21750 368d9abec10586250cff09ae21419f72 380 Gene3D G3DSA:2.40.50.100 157 192 2.5E-27 T 13-09-2016 THL1_RS21750 368d9abec10586250cff09ae21419f72 380 Gene3D G3DSA:2.40.50.100 63 96 2.5E-27 T 13-09-2016 THL1_RS21750 368d9abec10586250cff09ae21419f72 380 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 38 360 8.9E-78 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS21750 368d9abec10586250cff09ae21419f72 380 PANTHER PTHR30158:SF3 1 375 1.7E-163 T 13-09-2016 THL1_RS25920 20c838ca21b427bcf1a7dc59ed303c9d 271 PANTHER PTHR11364 11 270 6.6E-66 T 13-09-2016 THL1_RS25920 20c838ca21b427bcf1a7dc59ed303c9d 271 Gene3D G3DSA:3.40.250.10 147 270 8.3E-33 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS25920 20c838ca21b427bcf1a7dc59ed303c9d 271 Gene3D G3DSA:3.40.250.10 7 135 5.0E-32 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS25920 20c838ca21b427bcf1a7dc59ed303c9d 271 SUPERFAMILY SSF52821 144 270 4.71E-29 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS25920 20c838ca21b427bcf1a7dc59ed303c9d 271 SMART SM00450 149 267 2.1E-20 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS25920 20c838ca21b427bcf1a7dc59ed303c9d 271 SMART SM00450 11 126 2.1E-16 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS25920 20c838ca21b427bcf1a7dc59ed303c9d 271 ProSitePatterns PS00380 Rhodanese signature 1. 36 47 - T 13-09-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 THL1_RS25920 20c838ca21b427bcf1a7dc59ed303c9d 271 Pfam PF00581 Rhodanese-like domain 155 263 6.6E-16 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS25920 20c838ca21b427bcf1a7dc59ed303c9d 271 Pfam PF00581 Rhodanese-like domain 13 122 1.0E-13 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS25920 20c838ca21b427bcf1a7dc59ed303c9d 271 PANTHER PTHR11364:SF0 11 270 6.6E-66 T 13-09-2016 THL1_RS25920 20c838ca21b427bcf1a7dc59ed303c9d 271 SUPERFAMILY SSF52821 3 129 1.57E-31 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS25920 20c838ca21b427bcf1a7dc59ed303c9d 271 ProSitePatterns PS00683 Rhodanese C-terminal signature. 251 261 - T 13-09-2016 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 THL1_RS23725 fb369df15e9eced8df2dd47aa2a40f58 907 Pfam PF00196 Bacterial regulatory proteins, luxR family 845 899 1.2E-17 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS23725 fb369df15e9eced8df2dd47aa2a40f58 907 SUPERFAMILY SSF48452 473 596 1.39E-6 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS23725 fb369df15e9eced8df2dd47aa2a40f58 907 SUPERFAMILY SSF52540 39 248 2.44E-9 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS23725 fb369df15e9eced8df2dd47aa2a40f58 907 Gene3D G3DSA:3.40.50.300 138 189 1.1E-4 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS23725 fb369df15e9eced8df2dd47aa2a40f58 907 Gene3D G3DSA:3.40.50.300 37 88 1.1E-4 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS23725 fb369df15e9eced8df2dd47aa2a40f58 907 Gene3D G3DSA:1.10.10.10 842 905 3.3E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS23725 fb369df15e9eced8df2dd47aa2a40f58 907 SMART SM00421 843 900 7.5E-23 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS23725 fb369df15e9eced8df2dd47aa2a40f58 907 SUPERFAMILY SSF46894 835 906 3.4E-20 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS23725 fb369df15e9eced8df2dd47aa2a40f58 907 Gene3D G3DSA:1.25.40.10 464 816 3.8E-29 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS23725 fb369df15e9eced8df2dd47aa2a40f58 907 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 846 860 8.8E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS23725 fb369df15e9eced8df2dd47aa2a40f58 907 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 876 888 8.8E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS23725 fb369df15e9eced8df2dd47aa2a40f58 907 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 860 876 8.8E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS23725 fb369df15e9eced8df2dd47aa2a40f58 907 SMART SM00382 46 206 0.0014 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS23725 fb369df15e9eced8df2dd47aa2a40f58 907 ProSitePatterns PS00622 LuxR-type HTH domain signature. 860 887 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07640 da452ac2d7fd127eb94fb866c5d898ce 541 Pfam PF00171 Aldehyde dehydrogenase family 63 505 1.1E-94 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS07640 da452ac2d7fd127eb94fb866c5d898ce 541 SUPERFAMILY SSF53720 23 511 2.49E-104 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS07640 da452ac2d7fd127eb94fb866c5d898ce 541 PANTHER PTHR11699:SF69 9 541 0.0 T 13-09-2016 THL1_RS07640 da452ac2d7fd127eb94fb866c5d898ce 541 Gene3D G3DSA:3.40.309.10 300 485 3.4E-47 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS07640 da452ac2d7fd127eb94fb866c5d898ce 541 PANTHER PTHR11699 9 541 0.0 T 13-09-2016 THL1_RS07640 da452ac2d7fd127eb94fb866c5d898ce 541 Gene3D G3DSA:3.40.605.10 31 299 2.8E-53 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS07640 da452ac2d7fd127eb94fb866c5d898ce 541 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 313 324 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS23940 97c1888d7b0c4e060271f3e89bda8e43 266 Pfam PF07103 Protein of unknown function (DUF1365) 5 245 3.9E-64 T 13-09-2016 IPR010775 Protein of unknown function DUF1365 THL1_RS23940 97c1888d7b0c4e060271f3e89bda8e43 266 PANTHER PTHR33973 2 244 1.2E-48 T 13-09-2016 THL1_RS07285 928414397080d03050f8dbe44926f7b5 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 81 4.7E-16 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS07285 928414397080d03050f8dbe44926f7b5 250 SUPERFAMILY SSF48008 87 223 1.33E-23 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS07285 928414397080d03050f8dbe44926f7b5 250 Gene3D G3DSA:1.10.10.10 14 82 3.0E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07285 928414397080d03050f8dbe44926f7b5 250 SMART SM00345 23 81 1.9E-15 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS07285 928414397080d03050f8dbe44926f7b5 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 9.9E-8 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS07285 928414397080d03050f8dbe44926f7b5 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 9.9E-8 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS07285 928414397080d03050f8dbe44926f7b5 250 SMART SM00895 91 215 3.5E-19 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS07285 928414397080d03050f8dbe44926f7b5 250 Gene3D G3DSA:1.20.120.530 84 228 1.6E-25 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS07285 928414397080d03050f8dbe44926f7b5 250 SUPERFAMILY SSF46785 15 85 1.0E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07285 928414397080d03050f8dbe44926f7b5 250 Pfam PF07729 FCD domain 91 214 1.2E-22 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS07285 928414397080d03050f8dbe44926f7b5 250 PANTHER PTHR11751 17 107 1.1E-23 T 13-09-2016 THL1_RS08855 a8d65bb34b39e207986966fa555b0ebf 585 SMART SM00382 366 548 2.8E-11 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS08855 a8d65bb34b39e207986966fa555b0ebf 585 Pfam PF00005 ABC transporter 362 502 6.4E-19 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS08855 a8d65bb34b39e207986966fa555b0ebf 585 Gene3D G3DSA:1.20.1560.10 14 326 3.6E-31 T 13-09-2016 THL1_RS08855 a8d65bb34b39e207986966fa555b0ebf 585 Gene3D G3DSA:3.40.50.300 362 564 1.9E-45 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08855 a8d65bb34b39e207986966fa555b0ebf 585 SUPERFAMILY SSF52540 362 564 7.24E-39 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08855 a8d65bb34b39e207986966fa555b0ebf 585 SUPERFAMILY SSF90123 14 326 1.06E-33 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS08855 a8d65bb34b39e207986966fa555b0ebf 585 PANTHER PTHR24221 22 581 1.5E-57 T 13-09-2016 THL1_RS08855 a8d65bb34b39e207986966fa555b0ebf 585 PANTHER PTHR24221:SF161 22 581 1.5E-57 T 13-09-2016 THL1_RS08855 a8d65bb34b39e207986966fa555b0ebf 585 Pfam PF00664 ABC transporter transmembrane region 22 295 1.2E-19 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS00010 31eceed930e8fe1e4e84128d5024c04d 367 Pfam PF02767 DNA polymerase III beta subunit, central domain 130 244 2.3E-38 T 13-09-2016 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00010 31eceed930e8fe1e4e84128d5024c04d 367 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 119 7.7E-43 T 13-09-2016 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00010 31eceed930e8fe1e4e84128d5024c04d 367 SUPERFAMILY SSF55979 246 367 2.2E-37 T 13-09-2016 THL1_RS00010 31eceed930e8fe1e4e84128d5024c04d 367 SUPERFAMILY SSF55979 126 245 1.0E-28 T 13-09-2016 THL1_RS00010 31eceed930e8fe1e4e84128d5024c04d 367 PANTHER PTHR30478 2 367 2.0E-146 T 13-09-2016 THL1_RS00010 31eceed930e8fe1e4e84128d5024c04d 367 Gene3D G3DSA:3.10.150.10 250 367 2.4E-38 T 13-09-2016 THL1_RS00010 31eceed930e8fe1e4e84128d5024c04d 367 SUPERFAMILY SSF55979 1 120 1.73E-30 T 13-09-2016 THL1_RS00010 31eceed930e8fe1e4e84128d5024c04d 367 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 367 1.2E-109 T 13-09-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00010 31eceed930e8fe1e4e84128d5024c04d 367 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 247 366 6.1E-41 T 13-09-2016 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00010 31eceed930e8fe1e4e84128d5024c04d 367 Gene3D G3DSA:3.10.150.10 126 249 3.7E-37 T 13-09-2016 THL1_RS00010 31eceed930e8fe1e4e84128d5024c04d 367 SMART SM00480 17 363 2.2E-164 T 13-09-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00010 31eceed930e8fe1e4e84128d5024c04d 367 PIRSF PIRSF000804 1 367 9.7E-123 T 13-09-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00010 31eceed930e8fe1e4e84128d5024c04d 367 Gene3D G3DSA:3.10.150.10 1 120 1.4E-35 T 13-09-2016 THL1_RS03770 37ac719d09e953548881d650c3c81b3b 133 Pfam PF01890 Cobalamin synthesis G C-terminus 3 127 3.9E-27 T 13-09-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 THL1_RS03770 37ac719d09e953548881d650c3c81b3b 133 PANTHER PTHR37477 1 127 7.6E-19 T 13-09-2016 THL1_RS03770 37ac719d09e953548881d650c3c81b3b 133 PANTHER PTHR37477:SF1 1 127 7.6E-19 T 13-09-2016 THL1_RS03770 37ac719d09e953548881d650c3c81b3b 133 SUPERFAMILY SSF159664 3 130 1.31E-33 T 13-09-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 THL1_RS03770 37ac719d09e953548881d650c3c81b3b 133 Gene3D G3DSA:3.30.420.180 2 128 1.3E-30 T 13-09-2016 IPR002750 CobE/GbiG C-terminal domain GO:0009236 THL1_RS24710 1e8c1fa80157fbafcc256024d3bdb328 485 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 378 479 3.3E-17 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24710 1e8c1fa80157fbafcc256024d3bdb328 485 Pfam PF00512 His Kinase A (phospho-acceptor) domain 269 329 9.0E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24710 1e8c1fa80157fbafcc256024d3bdb328 485 SUPERFAMILY SSF47384 264 330 2.55E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24710 1e8c1fa80157fbafcc256024d3bdb328 485 Gene3D G3DSA:1.10.287.130 270 328 1.8E-10 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24710 1e8c1fa80157fbafcc256024d3bdb328 485 PANTHER PTHR24423 177 218 1.3E-42 T 13-09-2016 THL1_RS24710 1e8c1fa80157fbafcc256024d3bdb328 485 PANTHER PTHR24423 265 481 1.3E-42 T 13-09-2016 THL1_RS24710 1e8c1fa80157fbafcc256024d3bdb328 485 SMART SM00388 269 333 3.1E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24710 1e8c1fa80157fbafcc256024d3bdb328 485 SMART SM00387 374 482 1.5E-22 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24710 1e8c1fa80157fbafcc256024d3bdb328 485 Gene3D G3DSA:3.30.565.10 336 477 2.1E-30 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24710 1e8c1fa80157fbafcc256024d3bdb328 485 SUPERFAMILY SSF55874 334 478 1.83E-31 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24710 1e8c1fa80157fbafcc256024d3bdb328 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 427 1.1E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS24710 1e8c1fa80157fbafcc256024d3bdb328 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 460 1.1E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS24710 1e8c1fa80157fbafcc256024d3bdb328 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 441 1.1E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS14185 157fdc7b15722a21cb90277efb83cee4 238 TIGRFAM TIGR03864 PQQ_ABC_ATP: ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system 3 237 9.0E-104 T 13-09-2016 IPR022467 ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system THL1_RS14185 157fdc7b15722a21cb90277efb83cee4 238 Pfam PF00005 ABC transporter 19 162 4.5E-29 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS14185 157fdc7b15722a21cb90277efb83cee4 238 SUPERFAMILY SSF52540 3 221 9.43E-55 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14185 157fdc7b15722a21cb90277efb83cee4 238 PANTHER PTHR24220 5 221 4.6E-66 T 13-09-2016 THL1_RS14185 157fdc7b15722a21cb90277efb83cee4 238 SMART SM00382 28 211 5.0E-14 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS14185 157fdc7b15722a21cb90277efb83cee4 238 Gene3D G3DSA:3.40.50.300 3 221 2.0E-60 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15975 9a15f0a9b65aeb9ba1445f75e68d9751 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.5E-19 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS15975 9a15f0a9b65aeb9ba1445f75e68d9751 302 Gene3D G3DSA:3.40.190.10 92 178 1.4E-20 T 13-09-2016 THL1_RS15975 9a15f0a9b65aeb9ba1445f75e68d9751 302 SUPERFAMILY SSF46785 3 85 2.38E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS15975 9a15f0a9b65aeb9ba1445f75e68d9751 302 Pfam PF03466 LysR substrate binding domain 89 294 1.6E-38 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS15975 9a15f0a9b65aeb9ba1445f75e68d9751 302 PANTHER PTHR30537:SF29 1 295 6.0E-95 T 13-09-2016 THL1_RS15975 9a15f0a9b65aeb9ba1445f75e68d9751 302 PANTHER PTHR30537 1 295 6.0E-95 T 13-09-2016 THL1_RS15975 9a15f0a9b65aeb9ba1445f75e68d9751 302 Gene3D G3DSA:1.10.10.10 3 85 6.7E-26 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS15975 9a15f0a9b65aeb9ba1445f75e68d9751 302 SUPERFAMILY SSF53850 89 297 9.95E-37 T 13-09-2016 THL1_RS15975 9a15f0a9b65aeb9ba1445f75e68d9751 302 Gene3D G3DSA:3.40.190.10 179 262 1.5E-15 T 13-09-2016 THL1_RS19045 211eb401fefc39111ff48f844ef9f8e2 231 PIRSF PIRSF026326 2 229 4.5E-65 T 13-09-2016 IPR027023 Putative lipopolysaccharide kinase InaA THL1_RS19045 211eb401fefc39111ff48f844ef9f8e2 231 SUPERFAMILY SSF56112 73 169 4.62E-11 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS19045 211eb401fefc39111ff48f844ef9f8e2 231 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 19 221 4.4E-48 T 13-09-2016 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 THL1_RS19045 211eb401fefc39111ff48f844ef9f8e2 231 Gene3D G3DSA:1.10.510.10 129 200 3.7E-5 T 13-09-2016 THL1_RS16425 75a3ad48508e559c84fe8827b618cf4c 257 Pfam PF00005 ABC transporter 17 171 1.2E-28 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS16425 75a3ad48508e559c84fe8827b618cf4c 257 SMART SM00382 26 219 1.5E-15 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS16425 75a3ad48508e559c84fe8827b618cf4c 257 SUPERFAMILY SSF52540 2 234 1.11E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16425 75a3ad48508e559c84fe8827b618cf4c 257 PANTHER PTHR24220:SF557 3 249 7.4E-57 T 13-09-2016 THL1_RS16425 75a3ad48508e559c84fe8827b618cf4c 257 PANTHER PTHR24220 3 249 7.4E-57 T 13-09-2016 THL1_RS16425 75a3ad48508e559c84fe8827b618cf4c 257 Gene3D G3DSA:3.40.50.300 2 242 7.9E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 SUPERFAMILY SSF50692 622 652 3.94E-42 T 13-09-2016 IPR009010 Aspartate decarboxylase-like domain THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 SUPERFAMILY SSF50692 682 811 3.94E-42 T 13-09-2016 IPR009010 Aspartate decarboxylase-like domain THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 Gene3D G3DSA:3.40.228.10 1 105 1.0E-72 T 13-09-2016 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 Gene3D G3DSA:3.40.228.10 150 262 1.0E-72 T 13-09-2016 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 PANTHER PTHR11615:SF149 675 810 9.9E-261 T 13-09-2016 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 PANTHER PTHR11615 287 382 9.9E-261 T 13-09-2016 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 PANTHER PTHR11615 576 651 9.9E-261 T 13-09-2016 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 PANTHER PTHR11615 1 183 9.9E-261 T 13-09-2016 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 Pfam PF00384 Molybdopterin oxidoreductase 2 379 8.0E-22 T 13-09-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 SUPERFAMILY SSF53706 1 643 3.5E-225 T 13-09-2016 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 1 810 0.0 T 13-09-2016 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 PANTHER PTHR11615 211 248 9.9E-261 T 13-09-2016 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 PANTHER PTHR11615 399 483 9.9E-261 T 13-09-2016 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 PANTHER PTHR11615 675 810 9.9E-261 T 13-09-2016 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 Gene3D G3DSA:2.40.40.20 603 649 3.4E-47 T 13-09-2016 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 Gene3D G3DSA:2.40.40.20 681 811 3.4E-47 T 13-09-2016 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 Pfam PF01568 Molydopterin dinucleotide binding domain 689 804 7.6E-13 T 13-09-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 Gene3D G3DSA:3.40.50.740 322 470 7.5E-54 T 13-09-2016 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 PANTHER PTHR11615:SF149 287 382 9.9E-261 T 13-09-2016 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 PANTHER PTHR11615:SF149 576 651 9.9E-261 T 13-09-2016 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 PANTHER PTHR11615:SF149 211 248 9.9E-261 T 13-09-2016 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 PANTHER PTHR11615:SF149 399 483 9.9E-261 T 13-09-2016 THL1_RS25285 1dc947fb91e914019e55dca2f06a6488 811 PANTHER PTHR11615:SF149 1 183 9.9E-261 T 13-09-2016 THL1_RS05660 6f14ff181966803f75388438067dbdb0 416 PANTHER PTHR32432:SF4 1 384 4.8E-170 T 13-09-2016 THL1_RS05660 6f14ff181966803f75388438067dbdb0 416 Gene3D G3DSA:3.90.640.10 235 297 1.0E-19 T 13-09-2016 THL1_RS05660 6f14ff181966803f75388438067dbdb0 416 SUPERFAMILY SSF53067 9 196 6.04E-62 T 13-09-2016 THL1_RS05660 6f14ff181966803f75388438067dbdb0 416 Gene3D G3DSA:3.30.420.40 158 209 4.1E-27 T 13-09-2016 THL1_RS05660 6f14ff181966803f75388438067dbdb0 416 Gene3D G3DSA:3.30.420.40 5 83 4.1E-27 T 13-09-2016 THL1_RS05660 6f14ff181966803f75388438067dbdb0 416 Pfam PF14450 Cell division protein FtsA 207 374 8.8E-26 T 13-09-2016 THL1_RS05660 6f14ff181966803f75388438067dbdb0 416 Pfam PF14450 Cell division protein FtsA 11 193 5.2E-11 T 13-09-2016 THL1_RS05660 6f14ff181966803f75388438067dbdb0 416 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 9 378 5.3E-157 T 13-09-2016 IPR020823 Cell division protein FtsA GO:0007049 THL1_RS05660 6f14ff181966803f75388438067dbdb0 416 Gene3D G3DSA:3.30.1490.110 100 157 1.6E-16 T 13-09-2016 THL1_RS05660 6f14ff181966803f75388438067dbdb0 416 SUPERFAMILY SSF53067 198 378 1.08E-51 T 13-09-2016 THL1_RS05660 6f14ff181966803f75388438067dbdb0 416 Hamap MF_02033 Cell division protein FtsA [ftsA]. 6 416 31.627 T 13-09-2016 IPR020823 Cell division protein FtsA GO:0007049 THL1_RS05660 6f14ff181966803f75388438067dbdb0 416 PANTHER PTHR32432 1 384 4.8E-170 T 13-09-2016 THL1_RS05660 6f14ff181966803f75388438067dbdb0 416 SMART SM00842 10 196 6.9E-107 T 13-09-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 THL1_RS05660 6f14ff181966803f75388438067dbdb0 416 Gene3D G3DSA:3.30.420.40 298 352 6.3E-36 T 13-09-2016 THL1_RS05660 6f14ff181966803f75388438067dbdb0 416 Gene3D G3DSA:3.30.420.40 210 234 6.3E-36 T 13-09-2016 THL1_RS05660 6f14ff181966803f75388438067dbdb0 416 PIRSF PIRSF003101 1 416 5.7E-160 T 13-09-2016 IPR020823 Cell division protein FtsA GO:0007049 THL1_RS05660 6f14ff181966803f75388438067dbdb0 416 Pfam PF02491 SHS2 domain inserted in FTSA 85 162 1.1E-31 T 13-09-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 192 3.5E-4 T 13-09-2016 THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 PANTHER PTHR24322 161 192 3.8E-57 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 PANTHER PTHR24322 10 145 3.8E-57 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.7E-29 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.7E-29 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.7E-29 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.7E-29 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.7E-29 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.7E-29 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 3.4E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 3.4E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 3.4E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 SUPERFAMILY SSF51735 3 250 1.65E-65 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 Pfam PF00106 short chain dehydrogenase 8 202 2.8E-51 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 Gene3D G3DSA:3.40.50.720 2 252 1.1E-73 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 PANTHER PTHR24322:SF356 161 192 3.8E-57 T 13-09-2016 THL1_RS15605 cb2d84b911d3689ee4b643312b605bcc 255 PANTHER PTHR24322:SF356 10 145 3.8E-57 T 13-09-2016 THL1_RS09815 4c8ad208e5ed5e03eb1e5ee5aa153f07 193 PANTHER PTHR23416:SF53 1 162 2.7E-49 T 13-09-2016 THL1_RS09815 4c8ad208e5ed5e03eb1e5ee5aa153f07 193 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 109 136 3.8E-5 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS09815 4c8ad208e5ed5e03eb1e5ee5aa153f07 193 SUPERFAMILY SSF51161 3 162 3.53E-42 T 13-09-2016 IPR011004 Trimeric LpxA-like THL1_RS09815 4c8ad208e5ed5e03eb1e5ee5aa153f07 193 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 14 49 1.1E-5 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS09815 4c8ad208e5ed5e03eb1e5ee5aa153f07 193 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 51 75 7.1E-5 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS09815 4c8ad208e5ed5e03eb1e5ee5aa153f07 193 Gene3D G3DSA:2.160.10.10 2 156 1.2E-41 T 13-09-2016 THL1_RS09815 4c8ad208e5ed5e03eb1e5ee5aa153f07 193 PANTHER PTHR23416 1 162 2.7E-49 T 13-09-2016 THL1_RS11075 239c4fdbc4742342e665cbd092682884 300 Gene3D G3DSA:3.40.190.10 92 176 2.8E-12 T 13-09-2016 THL1_RS11075 239c4fdbc4742342e665cbd092682884 300 Pfam PF03466 LysR substrate binding domain 88 289 1.2E-28 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS11075 239c4fdbc4742342e665cbd092682884 300 SUPERFAMILY SSF53850 90 295 7.96E-31 T 13-09-2016 THL1_RS11075 239c4fdbc4742342e665cbd092682884 300 PANTHER PTHR30537 1 287 3.9E-67 T 13-09-2016 THL1_RS11075 239c4fdbc4742342e665cbd092682884 300 Gene3D G3DSA:1.10.10.10 3 85 1.4E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11075 239c4fdbc4742342e665cbd092682884 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.1E-16 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS11075 239c4fdbc4742342e665cbd092682884 300 Gene3D G3DSA:3.40.190.10 177 259 6.9E-15 T 13-09-2016 THL1_RS11075 239c4fdbc4742342e665cbd092682884 300 SUPERFAMILY SSF46785 4 103 1.36E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12265 e31dfbe32cc95b3576f5933c0091f273 182 PANTHER PTHR10849:SF13 14 182 2.8E-82 T 13-09-2016 THL1_RS12265 e31dfbe32cc95b3576f5933c0091f273 182 SUPERFAMILY SSF54862 35 161 2.93E-29 T 13-09-2016 THL1_RS12265 e31dfbe32cc95b3576f5933c0091f273 182 PANTHER PTHR10849 14 182 2.8E-82 T 13-09-2016 THL1_RS12265 e31dfbe32cc95b3576f5933c0091f273 182 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 62 73 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS12265 e31dfbe32cc95b3576f5933c0091f273 182 Gene3D G3DSA:1.10.1060.10 11 122 2.7E-19 T 13-09-2016 THL1_RS12265 e31dfbe32cc95b3576f5933c0091f273 182 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 101 112 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS12265 e31dfbe32cc95b3576f5933c0091f273 182 Pfam PF12838 4Fe-4S dicluster domain 61 115 1.3E-11 T 13-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THL1_RS12265 e31dfbe32cc95b3576f5933c0091f273 182 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 9 152 27.704 T 13-09-2016 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 THL1_RS12265 e31dfbe32cc95b3576f5933c0091f273 182 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 18 139 5.9E-53 T 13-09-2016 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 THL1_RS18825 23b23583e95f0495039b3ddca231c855 312 SUPERFAMILY SSF46626 55 78 7.42E-32 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18825 23b23583e95f0495039b3ddca231c855 312 SUPERFAMILY SSF46626 111 207 7.42E-32 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18825 23b23583e95f0495039b3ddca231c855 312 Gene3D G3DSA:1.10.760.10 60 82 7.2E-31 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18825 23b23583e95f0495039b3ddca231c855 312 Gene3D G3DSA:1.10.760.10 126 207 7.2E-31 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18825 23b23583e95f0495039b3ddca231c855 312 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 37 83 5.2E-23 T 13-09-2016 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal UniPathway: UPA00705 THL1_RS18825 23b23583e95f0495039b3ddca231c855 312 Gene3D G3DSA:1.10.760.10 221 305 6.8E-24 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18825 23b23583e95f0495039b3ddca231c855 312 SUPERFAMILY SSF46626 219 303 2.76E-22 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18825 23b23583e95f0495039b3ddca231c855 312 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 131 205 7.7E-16 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18825 23b23583e95f0495039b3ddca231c855 312 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 222 298 7.4E-12 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18825 23b23583e95f0495039b3ddca231c855 312 PRINTS PR00605 Class IC cytochrome C signature 183 205 8.5E-6 T 13-09-2016 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 THL1_RS18825 23b23583e95f0495039b3ddca231c855 312 PRINTS PR00605 Class IC cytochrome C signature 141 152 8.5E-6 T 13-09-2016 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 THL1_RS18825 23b23583e95f0495039b3ddca231c855 312 PIRSF PIRSF000006 1 305 9.0E-104 T 13-09-2016 IPR004678 Cytochrome c oxidase cbb3-type, subunit III UniPathway: UPA00705 THL1_RS18825 23b23583e95f0495039b3ddca231c855 312 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 36 304 3.9E-83 T 13-09-2016 IPR004678 Cytochrome c oxidase cbb3-type, subunit III UniPathway: UPA00705 THL1_RS18825 23b23583e95f0495039b3ddca231c855 312 PANTHER PTHR33751:SF1 97 308 4.8E-123 T 13-09-2016 THL1_RS18825 23b23583e95f0495039b3ddca231c855 312 PANTHER PTHR33751:SF1 25 79 4.8E-123 T 13-09-2016 THL1_RS18825 23b23583e95f0495039b3ddca231c855 312 PANTHER PTHR33751 97 308 4.8E-123 T 13-09-2016 THL1_RS18825 23b23583e95f0495039b3ddca231c855 312 PANTHER PTHR33751 25 79 4.8E-123 T 13-09-2016 THL1_RS04150 c3730e08c814afece6c464c9098417bb 288 Pfam PF00753 Metallo-beta-lactamase superfamily 42 257 3.7E-23 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS04150 c3730e08c814afece6c464c9098417bb 288 PANTHER PTHR23200 3 286 8.2E-91 T 13-09-2016 THL1_RS04150 c3730e08c814afece6c464c9098417bb 288 PANTHER PTHR23200:SF41 3 286 8.2E-91 T 13-09-2016 THL1_RS04150 c3730e08c814afece6c464c9098417bb 288 SMART SM00849 43 257 3.4E-18 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS04150 c3730e08c814afece6c464c9098417bb 288 SUPERFAMILY SSF56281 4 269 5.77E-37 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS04150 c3730e08c814afece6c464c9098417bb 288 Gene3D G3DSA:3.60.15.10 4 271 1.6E-41 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS23795 4735c15d756ed4a163f37717880dafce 327 Gene3D G3DSA:3.90.25.10 216 324 2.4E-8 T 13-09-2016 THL1_RS23795 4735c15d756ed4a163f37717880dafce 327 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 226 2.1E-17 T 13-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 THL1_RS23795 4735c15d756ed4a163f37717880dafce 327 SUPERFAMILY SSF51735 290 326 1.13E-44 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23795 4735c15d756ed4a163f37717880dafce 327 SUPERFAMILY SSF51735 2 251 1.13E-44 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23795 4735c15d756ed4a163f37717880dafce 327 PANTHER PTHR10366 2 327 1.0E-128 T 13-09-2016 THL1_RS23795 4735c15d756ed4a163f37717880dafce 327 PANTHER PTHR10366:SF446 2 327 1.0E-128 T 13-09-2016 THL1_RS23795 4735c15d756ed4a163f37717880dafce 327 Gene3D G3DSA:3.40.50.720 2 215 4.1E-30 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS14155 9d44c948a13e905c1084452360b1b636 220 SUPERFAMILY SSF52172 2 131 6.97E-28 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS14155 9d44c948a13e905c1084452360b1b636 220 SUPERFAMILY SSF46894 141 212 9.86E-18 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS14155 9d44c948a13e905c1084452360b1b636 220 SMART SM00421 152 209 5.4E-20 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS14155 9d44c948a13e905c1084452360b1b636 220 Gene3D G3DSA:1.10.10.10 141 210 2.3E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14155 9d44c948a13e905c1084452360b1b636 220 Pfam PF00072 Response regulator receiver domain 4 117 1.5E-28 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS14155 9d44c948a13e905c1084452360b1b636 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 3.3E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS14155 9d44c948a13e905c1084452360b1b636 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 3.3E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS14155 9d44c948a13e905c1084452360b1b636 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 3.3E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS14155 9d44c948a13e905c1084452360b1b636 220 SMART SM00448 2 116 3.9E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS14155 9d44c948a13e905c1084452360b1b636 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS14155 9d44c948a13e905c1084452360b1b636 220 PANTHER PTHR26402 2 209 1.8E-74 T 13-09-2016 THL1_RS14155 9d44c948a13e905c1084452360b1b636 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 6.1E-21 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS14155 9d44c948a13e905c1084452360b1b636 220 PANTHER PTHR26402:SF511 2 209 1.8E-74 T 13-09-2016 THL1_RS14155 9d44c948a13e905c1084452360b1b636 220 Gene3D G3DSA:3.40.50.2300 2 128 4.0E-29 T 13-09-2016 THL1_RS02610 e62f4677471624f0dd3d3cf6d0a675e6 332 SUPERFAMILY SSF53659 4 326 2.88E-111 T 13-09-2016 THL1_RS02610 e62f4677471624f0dd3d3cf6d0a675e6 332 PANTHER PTHR30004 1 325 2.2E-196 T 13-09-2016 THL1_RS02610 e62f4677471624f0dd3d3cf6d0a675e6 332 Gene3D G3DSA:3.40.718.10 2 328 1.5E-131 T 13-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 THL1_RS02610 e62f4677471624f0dd3d3cf6d0a675e6 332 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 6 325 3.2E-125 T 13-09-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 THL1_RS02610 e62f4677471624f0dd3d3cf6d0a675e6 332 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 2 325 35.448 T 13-09-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 THL1_RS02610 e62f4677471624f0dd3d3cf6d0a675e6 332 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 34 321 8.3E-107 T 13-09-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 THL1_RS02610 e62f4677471624f0dd3d3cf6d0a675e6 332 PANTHER PTHR30004:SF5 1 325 2.2E-196 T 13-09-2016 THL1_RS02465 b26fbe891ac325bbdaef2ab1fce6e941 315 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 132 285 1.3E-63 T 13-09-2016 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 THL1_RS02465 b26fbe891ac325bbdaef2ab1fce6e941 315 SUPERFAMILY SSF51735 1 156 7.74E-30 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS02465 b26fbe891ac325bbdaef2ab1fce6e941 315 PANTHER PTHR41706 1 315 3.8E-136 T 13-09-2016 THL1_RS02465 b26fbe891ac325bbdaef2ab1fce6e941 315 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 121 1.7E-11 T 13-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THL1_RS02465 b26fbe891ac325bbdaef2ab1fce6e941 315 Gene3D G3DSA:3.40.50.720 1 144 2.7E-75 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS02465 b26fbe891ac325bbdaef2ab1fce6e941 315 PIRSF PIRSF015689 1 315 6.6E-131 T 13-09-2016 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 THL1_RS02465 b26fbe891ac325bbdaef2ab1fce6e941 315 SUPERFAMILY SSF55347 132 285 3.99E-66 T 13-09-2016 THL1_RS02465 b26fbe891ac325bbdaef2ab1fce6e941 315 Gene3D G3DSA:3.30.360.10 145 285 2.8E-74 T 13-09-2016 THL1_RS02465 b26fbe891ac325bbdaef2ab1fce6e941 315 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 4 309 4.1E-141 T 13-09-2016 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 THL1_RS02465 b26fbe891ac325bbdaef2ab1fce6e941 315 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 315 146.656 T 13-09-2016 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 THL1_RS02465 b26fbe891ac325bbdaef2ab1fce6e941 315 SMART SM00859 6 124 5.1E-17 T 13-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THL1_RS24380 264b484b2a8c500a3ccd64b422b32cb1 89 Gene3D G3DSA:1.10.287.10 3 89 1.8E-37 T 13-09-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 THL1_RS24380 264b484b2a8c500a3ccd64b422b32cb1 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 20.904 T 13-09-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 THL1_RS24380 264b484b2a8c500a3ccd64b422b32cb1 89 Pfam PF00312 Ribosomal protein S15 8 88 3.5E-36 T 13-09-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS24380 264b484b2a8c500a3ccd64b422b32cb1 89 SUPERFAMILY SSF47060 3 89 1.94E-34 T 13-09-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 THL1_RS24380 264b484b2a8c500a3ccd64b422b32cb1 89 PANTHER PTHR23321 1 89 3.0E-44 T 13-09-2016 THL1_RS24380 264b484b2a8c500a3ccd64b422b32cb1 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 13-09-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS24380 264b484b2a8c500a3ccd64b422b32cb1 89 SMART SM01387 8 88 1.2E-49 T 13-09-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS24380 264b484b2a8c500a3ccd64b422b32cb1 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 3.0E-39 T 13-09-2016 THL1_RS24380 264b484b2a8c500a3ccd64b422b32cb1 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 6.7E-38 T 13-09-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 THL1_RS10685 5420060a9e1e22c40ddb8bbb54ba578a 465 PANTHER PTHR11785:SF26 1 461 5.9E-304 T 13-09-2016 THL1_RS10685 5420060a9e1e22c40ddb8bbb54ba578a 465 PANTHER PTHR11785 1 461 5.9E-304 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS10685 5420060a9e1e22c40ddb8bbb54ba578a 465 ProSitePatterns PS00218 Amino acid permeases signature. 44 74 - T 13-09-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 THL1_RS10685 5420060a9e1e22c40ddb8bbb54ba578a 465 PIRSF PIRSF006060 2 463 1.6E-72 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS10685 5420060a9e1e22c40ddb8bbb54ba578a 465 Pfam PF00324 Amino acid permease 19 461 2.0E-118 T 13-09-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 THL1_RS07125 5ae04be8c32c55f4338eb600be34cf24 152 PANTHER PTHR13078 14 143 6.3E-34 T 13-09-2016 THL1_RS07125 5ae04be8c32c55f4338eb600be34cf24 152 Pfam PF01575 MaoC like domain 14 131 1.1E-23 T 13-09-2016 IPR002539 MaoC-like domain THL1_RS07125 5ae04be8c32c55f4338eb600be34cf24 152 SUPERFAMILY SSF54637 5 147 1.27E-31 T 13-09-2016 IPR029069 HotDog domain THL1_RS07125 5ae04be8c32c55f4338eb600be34cf24 152 Gene3D G3DSA:3.10.129.10 14 139 1.5E-28 T 13-09-2016 IPR029069 HotDog domain THL1_RS23315 2919bd8b96be6b04fa3851d65f0c22d7 329 PANTHER PTHR10366:SF418 2 258 1.3E-91 T 13-09-2016 THL1_RS23315 2919bd8b96be6b04fa3851d65f0c22d7 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 227 1.7E-35 T 13-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 THL1_RS23315 2919bd8b96be6b04fa3851d65f0c22d7 329 Gene3D G3DSA:3.40.50.720 1 320 1.6E-61 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23315 2919bd8b96be6b04fa3851d65f0c22d7 329 SUPERFAMILY SSF51735 1 263 4.31E-70 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23315 2919bd8b96be6b04fa3851d65f0c22d7 329 SUPERFAMILY SSF51735 293 325 4.31E-70 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23315 2919bd8b96be6b04fa3851d65f0c22d7 329 PANTHER PTHR10366 284 328 1.3E-91 T 13-09-2016 THL1_RS23315 2919bd8b96be6b04fa3851d65f0c22d7 329 PANTHER PTHR10366 2 258 1.3E-91 T 13-09-2016 THL1_RS23315 2919bd8b96be6b04fa3851d65f0c22d7 329 PANTHER PTHR10366:SF418 284 328 1.3E-91 T 13-09-2016 THL1_RS07800 e9c8226583510f9e33a58f3b9fc4653b 425 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 9 419 5.8E-162 T 13-09-2016 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 THL1_RS07800 e9c8226583510f9e33a58f3b9fc4653b 425 SUPERFAMILY SSF53383 21 424 3.23E-133 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS07800 e9c8226583510f9e33a58f3b9fc4653b 425 Gene3D G3DSA:3.40.640.10 59 303 2.5E-85 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS07800 e9c8226583510f9e33a58f3b9fc4653b 425 PANTHER PTHR11986 1 424 2.4E-285 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS07800 e9c8226583510f9e33a58f3b9fc4653b 425 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 273 - T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS07800 e9c8226583510f9e33a58f3b9fc4653b 425 Gene3D G3DSA:3.90.1150.10 304 425 5.0E-39 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS07800 e9c8226583510f9e33a58f3b9fc4653b 425 Pfam PF00202 Aminotransferase class-III 17 420 1.4E-133 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS07800 e9c8226583510f9e33a58f3b9fc4653b 425 PANTHER PTHR11986:SF70 1 424 2.4E-285 T 13-09-2016 THL1_RS18660 acf54cbe09766592a22a57ca8be952ab 326 SUPERFAMILY SSF53659 1 324 6.58E-101 T 13-09-2016 THL1_RS18660 acf54cbe09766592a22a57ca8be952ab 326 PIRSF PIRSF002465 1 325 3.6E-118 T 13-09-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UniPathway: UPA00085 THL1_RS18660 acf54cbe09766592a22a57ca8be952ab 326 Pfam PF02504 Fatty acid synthesis protein 1 315 3.7E-96 T 13-09-2016 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 UniPathway: UPA00085 THL1_RS18660 acf54cbe09766592a22a57ca8be952ab 326 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 323 2.7E-100 T 13-09-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UniPathway: UPA00085 THL1_RS18660 acf54cbe09766592a22a57ca8be952ab 326 PANTHER PTHR30100 1 326 4.5E-125 T 13-09-2016 THL1_RS18660 acf54cbe09766592a22a57ca8be952ab 326 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 326 143.278 T 13-09-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UniPathway: UPA00085 THL1_RS18660 acf54cbe09766592a22a57ca8be952ab 326 PANTHER PTHR30100:SF1 1 326 4.5E-125 T 13-09-2016 THL1_RS18660 acf54cbe09766592a22a57ca8be952ab 326 Gene3D G3DSA:3.40.718.10 1 323 6.3E-124 T 13-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 THL1_RS23075 2927d9767c0712d3d088a317d25a455c 250 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 4 230 1.1E-99 T 13-09-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THL1_RS23075 2927d9767c0712d3d088a317d25a455c 250 SUPERFAMILY SSF75217 4 247 8.5E-101 T 13-09-2016 IPR029028 Alpha/beta knot methyltransferases THL1_RS23075 2927d9767c0712d3d088a317d25a455c 250 PANTHER PTHR32125:SF1 1 231 1.7E-117 T 13-09-2016 THL1_RS23075 2927d9767c0712d3d088a317d25a455c 250 PIRSF PIRSF000386 4 249 4.6E-99 T 13-09-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THL1_RS23075 2927d9767c0712d3d088a317d25a455c 250 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 26 223 2.7E-65 T 13-09-2016 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THL1_RS23075 2927d9767c0712d3d088a317d25a455c 250 PANTHER PTHR32125 1 231 1.7E-117 T 13-09-2016 THL1_RS23075 2927d9767c0712d3d088a317d25a455c 250 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 250 116.475 T 13-09-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THL1_RS23075 2927d9767c0712d3d088a317d25a455c 250 Gene3D G3DSA:3.40.1280.10 3 163 1.3E-68 T 13-09-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THL1_RS23075 2927d9767c0712d3d088a317d25a455c 250 Gene3D G3DSA:1.10.1270.20 164 246 2.2E-34 T 13-09-2016 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THL1_RS16015 4571f466618e04397acd77311d189ee1 310 Gene3D G3DSA:3.40.50.300 2 233 1.9E-70 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16015 4571f466618e04397acd77311d189ee1 310 PANTHER PTHR24220:SF305 6 302 2.5E-175 T 13-09-2016 THL1_RS16015 4571f466618e04397acd77311d189ee1 310 SMART SM00382 30 215 4.9E-11 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS16015 4571f466618e04397acd77311d189ee1 310 SUPERFAMILY SSF52540 4 231 2.72E-63 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16015 4571f466618e04397acd77311d189ee1 310 PANTHER PTHR24220 6 302 2.5E-175 T 13-09-2016 THL1_RS16015 4571f466618e04397acd77311d189ee1 310 Pfam PF00005 ABC transporter 21 165 6.4E-30 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS16015 4571f466618e04397acd77311d189ee1 310 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS05780 b826fae98259f602ddd32e865f6f7d46 161 Pfam PF12680 SnoaL-like domain 10 110 1.7E-14 T 13-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain THL1_RS05780 b826fae98259f602ddd32e865f6f7d46 161 SUPERFAMILY SSF54427 3 133 1.88E-29 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS05780 b826fae98259f602ddd32e865f6f7d46 161 Gene3D G3DSA:3.10.450.50 1 123 1.1E-24 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS12945 b4de099073a0cbb42b4ed9a896c3b0cf 353 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 6 335 2.0E-133 T 13-09-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 THL1_RS12945 b4de099073a0cbb42b4ed9a896c3b0cf 353 PIRSF PIRSF005508 1 348 3.4E-132 T 13-09-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 THL1_RS12945 b4de099073a0cbb42b4ed9a896c3b0cf 353 PANTHER PTHR10361:SF31 5 343 1.7E-148 T 13-09-2016 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 THL1_RS12945 b4de099073a0cbb42b4ed9a896c3b0cf 353 PANTHER PTHR10361 5 343 1.7E-148 T 13-09-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 THL1_RS12945 b4de099073a0cbb42b4ed9a896c3b0cf 353 Pfam PF01758 Sodium Bile acid symporter family 51 247 4.3E-65 T 13-09-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 THL1_RS08375 b70fadfcd0b8ff5517442f913eaa1ccf 212 PANTHER PTHR10204:SF16 1 210 1.5E-70 T 13-09-2016 THL1_RS08375 b70fadfcd0b8ff5517442f913eaa1ccf 212 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 209 26.943 T 13-09-2016 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 THL1_RS08375 b70fadfcd0b8ff5517442f913eaa1ccf 212 Gene3D G3DSA:3.40.50.360 1 211 1.4E-52 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS08375 b70fadfcd0b8ff5517442f913eaa1ccf 212 Pfam PF02525 Flavodoxin-like fold 3 206 2.3E-40 T 13-09-2016 IPR003680 Flavodoxin-like fold THL1_RS08375 b70fadfcd0b8ff5517442f913eaa1ccf 212 SUPERFAMILY SSF52218 1 211 1.32E-42 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS08375 b70fadfcd0b8ff5517442f913eaa1ccf 212 PANTHER PTHR10204 1 210 1.5E-70 T 13-09-2016 THL1_RS25855 e2ecd00089ba23864f8b823cf47c9ded 433 SUPERFAMILY SSF54980 370 421 1.01E-7 T 13-09-2016 IPR009022 Elongation factor G, III-V domain THL1_RS25855 e2ecd00089ba23864f8b823cf47c9ded 433 PANTHER PTHR10229 2 433 1.3E-177 T 13-09-2016 IPR016496 GTPase HflX GO:0005525 THL1_RS25855 e2ecd00089ba23864f8b823cf47c9ded 433 Hamap MF_00900 GTPase HflX [hflX]. 28 391 46.391 T 13-09-2016 IPR016496 GTPase HflX GO:0005525 THL1_RS25855 e2ecd00089ba23864f8b823cf47c9ded 433 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 222 240 6.0E-10 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS25855 e2ecd00089ba23864f8b823cf47c9ded 433 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 268 286 6.0E-10 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS25855 e2ecd00089ba23864f8b823cf47c9ded 433 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 201 221 6.0E-10 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS25855 e2ecd00089ba23864f8b823cf47c9ded 433 Pfam PF16360 GTP-binding GTPase Middle Region 115 193 2.3E-29 T 13-09-2016 IPR032305 GTP-binding protein, middle domain THL1_RS25855 e2ecd00089ba23864f8b823cf47c9ded 433 Gene3D G3DSA:3.40.50.300 198 362 3.1E-35 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25855 e2ecd00089ba23864f8b823cf47c9ded 433 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 11 361 1.5E-154 T 13-09-2016 IPR016496 GTPase HflX GO:0005525 THL1_RS25855 e2ecd00089ba23864f8b823cf47c9ded 433 Pfam PF01926 50S ribosome-binding GTPase 201 319 2.4E-21 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS25855 e2ecd00089ba23864f8b823cf47c9ded 433 PANTHER PTHR10229:SF0 2 433 1.3E-177 T 13-09-2016 THL1_RS25855 e2ecd00089ba23864f8b823cf47c9ded 433 Pfam PF13167 GTP-binding GTPase N-terminal 28 113 7.6E-30 T 13-09-2016 IPR025121 GTPase HflX, N-terminal THL1_RS25855 e2ecd00089ba23864f8b823cf47c9ded 433 PIRSF PIRSF006809 5 421 8.8E-147 T 13-09-2016 IPR016496 GTPase HflX GO:0005525 THL1_RS25855 e2ecd00089ba23864f8b823cf47c9ded 433 SUPERFAMILY SSF52540 198 369 7.92E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22440 3852643deeec7a2a56fed32075b80cc9 236 PANTHER PTHR21392:SF1 1 235 2.2E-110 T 13-09-2016 THL1_RS22440 3852643deeec7a2a56fed32075b80cc9 236 PANTHER PTHR21392 1 235 2.2E-110 T 13-09-2016 THL1_RS22440 3852643deeec7a2a56fed32075b80cc9 236 Pfam PF03942 DTW domain 28 213 2.2E-42 T 13-09-2016 IPR005636 DTW THL1_RS22440 3852643deeec7a2a56fed32075b80cc9 236 SMART SM01144 26 218 6.9E-75 T 13-09-2016 IPR005636 DTW THL1_RS15460 e8ab244b9ca5bbc97be6958ae650fc81 422 SUPERFAMILY SSF111369 79 317 2.22E-58 T 13-09-2016 THL1_RS15460 e8ab244b9ca5bbc97be6958ae650fc81 422 Pfam PF13437 HlyD family secretion protein 201 302 5.6E-8 T 13-09-2016 THL1_RS15460 e8ab244b9ca5bbc97be6958ae650fc81 422 PANTHER PTHR30469 61 405 1.3E-179 T 13-09-2016 THL1_RS15460 e8ab244b9ca5bbc97be6958ae650fc81 422 Gene3D G3DSA:2.40.50.100 89 123 1.0E-22 T 13-09-2016 THL1_RS15460 e8ab244b9ca5bbc97be6958ae650fc81 422 Gene3D G3DSA:2.40.50.100 198 233 1.0E-22 T 13-09-2016 THL1_RS15460 e8ab244b9ca5bbc97be6958ae650fc81 422 Pfam PF13533 Biotin-lipoyl like 90 138 4.9E-15 T 13-09-2016 THL1_RS15460 e8ab244b9ca5bbc97be6958ae650fc81 422 PANTHER PTHR30469:SF12 4 44 1.3E-179 T 13-09-2016 IPR022824 Multidrug resistance protein MdtA THL1_RS15460 e8ab244b9ca5bbc97be6958ae650fc81 422 PANTHER PTHR30469:SF12 61 405 1.3E-179 T 13-09-2016 IPR022824 Multidrug resistance protein MdtA THL1_RS15460 e8ab244b9ca5bbc97be6958ae650fc81 422 PANTHER PTHR30469 4 44 1.3E-179 T 13-09-2016 THL1_RS15460 e8ab244b9ca5bbc97be6958ae650fc81 422 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 65 393 8.2E-75 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS17815 98c85bffd9360f4574d2be1d15fa30b0 255 Gene3D G3DSA:3.40.50.720 5 254 1.5E-84 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS17815 98c85bffd9360f4574d2be1d15fa30b0 255 SUPERFAMILY SSF51735 10 253 2.65E-83 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS17815 98c85bffd9360f4574d2be1d15fa30b0 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 253 1.5E-66 T 13-09-2016 THL1_RS17815 98c85bffd9360f4574d2be1d15fa30b0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 6.5E-41 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17815 98c85bffd9360f4574d2be1d15fa30b0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 6.5E-41 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17815 98c85bffd9360f4574d2be1d15fa30b0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 6.5E-41 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17815 98c85bffd9360f4574d2be1d15fa30b0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 6.5E-41 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17815 98c85bffd9360f4574d2be1d15fa30b0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 6.5E-41 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17815 98c85bffd9360f4574d2be1d15fa30b0 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 6.5E-41 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17815 98c85bffd9360f4574d2be1d15fa30b0 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 1.0E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17815 98c85bffd9360f4574d2be1d15fa30b0 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.0E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17815 98c85bffd9360f4574d2be1d15fa30b0 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.0E-11 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17815 98c85bffd9360f4574d2be1d15fa30b0 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS17815 98c85bffd9360f4574d2be1d15fa30b0 255 PANTHER PTHR24322:SF409 161 193 9.1E-84 T 13-09-2016 THL1_RS17815 98c85bffd9360f4574d2be1d15fa30b0 255 PANTHER PTHR24322:SF409 16 145 9.1E-84 T 13-09-2016 THL1_RS17815 98c85bffd9360f4574d2be1d15fa30b0 255 PANTHER PTHR24322 161 193 9.1E-84 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17815 98c85bffd9360f4574d2be1d15fa30b0 255 PANTHER PTHR24322 16 145 9.1E-84 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS00535 83aaf5e15323fc0c53981d55a4cac1a2 456 Gene3D G3DSA:2.50.20.10 343 451 1.3E-36 T 13-09-2016 THL1_RS00535 83aaf5e15323fc0c53981d55a4cac1a2 456 Gene3D G3DSA:2.50.20.10 162 310 1.3E-36 T 13-09-2016 THL1_RS00535 83aaf5e15323fc0c53981d55a4cac1a2 456 Pfam PF07044 Protein of unknown function (DUF1329) 84 451 2.6E-151 T 13-09-2016 IPR010752 Protein of unknown function DUF1329 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 81 97 7.7E-5 T 13-09-2016 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 10 24 7.7E-5 T 13-09-2016 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 51 65 7.7E-5 T 13-09-2016 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 Gene3D G3DSA:3.40.50.620 223 399 4.9E-60 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 SUPERFAMILY SSF52402 197 420 1.3E-58 T 13-09-2016 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 Pfam PF00117 Glutamine amidotransferase class-I 12 200 3.0E-36 T 13-09-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 212 525 4.1E-149 T 13-09-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 PRINTS PR00097 Anthranilate synthase component II signature 177 190 1.5E-5 T 13-09-2016 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 PRINTS PR00097 Anthranilate synthase component II signature 54 63 1.5E-5 T 13-09-2016 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 PRINTS PR00097 Anthranilate synthase component II signature 81 92 1.5E-5 T 13-09-2016 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 Pfam PF02540 NAD synthase 216 291 7.1E-8 T 13-09-2016 IPR022310 NAD/GMP synthase THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 Gene3D G3DSA:3.40.50.880 6 222 3.7E-59 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 5.1E-7 T 13-09-2016 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 5.1E-7 T 13-09-2016 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 177 190 5.1E-7 T 13-09-2016 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 Pfam PF00958 GMP synthase C terminal domain 433 524 1.2E-41 T 13-09-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 10 204 4.9E-78 T 13-09-2016 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 PANTHER PTHR11922 1 522 1.2E-283 T 13-09-2016 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 SUPERFAMILY SSF54810 405 525 2.48E-49 T 13-09-2016 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 SUPERFAMILY SSF52317 8 237 1.7E-54 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 7 525 55.963 T 13-09-2016 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 PANTHER PTHR11922:SF2 1 522 1.2E-283 T 13-09-2016 THL1_RS06055 8dc02cc867cd8d7c3e9d33b80bca2a85 525 Gene3D G3DSA:3.30.300.10 401 525 6.3E-53 T 13-09-2016 THL1_RS19480 d4c27f4c767c00fb32a1376130742f87 295 SUPERFAMILY SSF103088 131 243 8.24E-30 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS19480 d4c27f4c767c00fb32a1376130742f87 295 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 4 54 3.3E-21 T 13-09-2016 IPR025713 Motility protein B, N-terminal domain THL1_RS19480 d4c27f4c767c00fb32a1376130742f87 295 PANTHER PTHR30329 1 267 6.3E-83 T 13-09-2016 THL1_RS19480 d4c27f4c767c00fb32a1376130742f87 295 PANTHER PTHR30329:SF4 1 267 6.3E-83 T 13-09-2016 THL1_RS19480 d4c27f4c767c00fb32a1376130742f87 295 Pfam PF00691 OmpA family 153 237 8.5E-16 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS19480 d4c27f4c767c00fb32a1376130742f87 295 Gene3D G3DSA:3.30.1330.60 119 243 2.7E-28 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS13810 329e0b01f1b746db538d28649b518666 316 SUPERFAMILY SSF46689 261 312 5.82E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13810 329e0b01f1b746db538d28649b518666 316 SMART SM00342 225 310 3.7E-27 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS13810 329e0b01f1b746db538d28649b518666 316 Gene3D G3DSA:1.10.10.60 261 312 1.1E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13810 329e0b01f1b746db538d28649b518666 316 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 261 306 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS13810 329e0b01f1b746db538d28649b518666 316 Pfam PF14525 AraC-binding-like domain 17 190 6.8E-14 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS13810 329e0b01f1b746db538d28649b518666 316 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 279 294 3.5E-7 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS13810 329e0b01f1b746db538d28649b518666 316 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 294 310 3.5E-7 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS13810 329e0b01f1b746db538d28649b518666 316 Gene3D G3DSA:1.10.10.60 213 260 2.1E-4 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13810 329e0b01f1b746db538d28649b518666 316 PANTHER PTHR11019:SF50 66 314 3.2E-34 T 13-09-2016 THL1_RS13810 329e0b01f1b746db538d28649b518666 316 Pfam PF12833 Helix-turn-helix domain 231 311 2.4E-22 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS13810 329e0b01f1b746db538d28649b518666 316 PANTHER PTHR11019:SF50 35 44 3.2E-34 T 13-09-2016 THL1_RS13810 329e0b01f1b746db538d28649b518666 316 PANTHER PTHR11019 66 314 3.2E-34 T 13-09-2016 THL1_RS13810 329e0b01f1b746db538d28649b518666 316 PANTHER PTHR11019 35 44 3.2E-34 T 13-09-2016 THL1_RS28150 f4725bb31b089102011625090348951f 210 Gene3D G3DSA:2.30.110.10 1 206 3.6E-76 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS28150 f4725bb31b089102011625090348951f 210 PIRSF PIRSF010372 1 209 5.3E-77 T 13-09-2016 IPR007396 Transcriptional regulator PAI 2-type THL1_RS28150 f4725bb31b089102011625090348951f 210 SUPERFAMILY SSF50475 10 193 9.47E-43 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS28150 f4725bb31b089102011625090348951f 210 PANTHER PTHR35802 2 206 2.6E-62 T 13-09-2016 THL1_RS28150 f4725bb31b089102011625090348951f 210 Pfam PF04299 Putative FMN-binding domain 1 168 7.2E-62 T 13-09-2016 IPR007396 Transcriptional regulator PAI 2-type THL1_RS28150 f4725bb31b089102011625090348951f 210 PANTHER PTHR35802:SF1 2 206 2.6E-62 T 13-09-2016 THL1_RS12250 f1ac7d9d78a31d5506ff8355ee69ed5a 615 PANTHER PTHR22773:SF50 1 570 3.7E-226 T 13-09-2016 THL1_RS12250 f1ac7d9d78a31d5506ff8355ee69ed5a 615 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 66 123 5.9E-20 T 13-09-2016 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal THL1_RS12250 f1ac7d9d78a31d5506ff8355ee69ed5a 615 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 8.1E-54 T 13-09-2016 THL1_RS12250 f1ac7d9d78a31d5506ff8355ee69ed5a 615 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 159 180 8.1E-54 T 13-09-2016 THL1_RS12250 f1ac7d9d78a31d5506ff8355ee69ed5a 615 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 249 275 8.1E-54 T 13-09-2016 THL1_RS12250 f1ac7d9d78a31d5506ff8355ee69ed5a 615 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 227 248 8.1E-54 T 13-09-2016 THL1_RS12250 f1ac7d9d78a31d5506ff8355ee69ed5a 615 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 8.1E-54 T 13-09-2016 THL1_RS12250 f1ac7d9d78a31d5506ff8355ee69ed5a 615 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 420 439 8.1E-54 T 13-09-2016 THL1_RS12250 f1ac7d9d78a31d5506ff8355ee69ed5a 615 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 317 329 8.1E-54 T 13-09-2016 THL1_RS12250 f1ac7d9d78a31d5506ff8355ee69ed5a 615 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 86 106 1.2E-8 T 13-09-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THL1_RS12250 f1ac7d9d78a31d5506ff8355ee69ed5a 615 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 60 84 1.2E-8 T 13-09-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THL1_RS12250 f1ac7d9d78a31d5506ff8355ee69ed5a 615 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 267 289 1.2E-8 T 13-09-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THL1_RS12250 f1ac7d9d78a31d5506ff8355ee69ed5a 615 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 419 441 1.2E-8 T 13-09-2016 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THL1_RS12250 f1ac7d9d78a31d5506ff8355ee69ed5a 615 PANTHER PTHR22773 1 570 3.7E-226 T 13-09-2016 THL1_RS12250 f1ac7d9d78a31d5506ff8355ee69ed5a 615 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 2 612 2.2E-228 T 13-09-2016 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 THL1_RS12250 f1ac7d9d78a31d5506ff8355ee69ed5a 615 Pfam PF00361 Proton-conducting membrane transporter 136 427 4.1E-88 T 13-09-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 THL1_RS21490 ab57d4977c57aff5b7e719330c93104e 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.2E-21 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS21490 ab57d4977c57aff5b7e719330c93104e 300 SUPERFAMILY SSF46785 2 112 1.72E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS21490 ab57d4977c57aff5b7e719330c93104e 300 Gene3D G3DSA:3.40.190.10 90 181 1.1E-16 T 13-09-2016 THL1_RS21490 ab57d4977c57aff5b7e719330c93104e 300 Gene3D G3DSA:1.10.10.10 3 86 3.3E-28 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS21490 ab57d4977c57aff5b7e719330c93104e 300 Gene3D G3DSA:3.40.190.10 182 257 1.7E-4 T 13-09-2016 THL1_RS21490 ab57d4977c57aff5b7e719330c93104e 300 SUPERFAMILY SSF53850 91 293 6.52E-31 T 13-09-2016 THL1_RS21490 ab57d4977c57aff5b7e719330c93104e 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.5E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS21490 ab57d4977c57aff5b7e719330c93104e 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.5E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS21490 ab57d4977c57aff5b7e719330c93104e 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.5E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS21490 ab57d4977c57aff5b7e719330c93104e 300 Pfam PF03466 LysR substrate binding domain 90 293 2.7E-31 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS21490 ab57d4977c57aff5b7e719330c93104e 300 PANTHER PTHR30126:SF32 1 297 1.7E-117 T 13-09-2016 THL1_RS21490 ab57d4977c57aff5b7e719330c93104e 300 PANTHER PTHR30126 1 297 1.7E-117 T 13-09-2016 THL1_RS05370 ac595aaa493775cf0e519d556e95bf14 241 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 3 241 1.1E-124 T 13-09-2016 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 THL1_RS05370 ac595aaa493775cf0e519d556e95bf14 241 SUPERFAMILY SSF52540 4 235 1.81E-63 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05370 ac595aaa493775cf0e519d556e95bf14 241 PANTHER PTHR24220:SF497 5 238 3.3E-149 T 13-09-2016 THL1_RS05370 ac595aaa493775cf0e519d556e95bf14 241 Gene3D G3DSA:3.40.50.300 3 233 5.7E-69 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05370 ac595aaa493775cf0e519d556e95bf14 241 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 214 236 1.7E-5 T 13-09-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal THL1_RS05370 ac595aaa493775cf0e519d556e95bf14 241 SMART SM00382 28 222 3.3E-8 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS05370 ac595aaa493775cf0e519d556e95bf14 241 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS05370 ac595aaa493775cf0e519d556e95bf14 241 PANTHER PTHR24220 5 238 3.3E-149 T 13-09-2016 THL1_RS05370 ac595aaa493775cf0e519d556e95bf14 241 Pfam PF00005 ABC transporter 20 166 4.7E-35 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS07465 eb3e1e226a8b5a4b0961396ba75c31d3 112 SMART SM00938 4 105 6.2E-61 T 13-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THL1_RS07465 eb3e1e226a8b5a4b0961396ba75c31d3 112 PANTHER PTHR30115 1 112 2.1E-63 T 13-09-2016 THL1_RS07465 eb3e1e226a8b5a4b0961396ba75c31d3 112 PIRSF PIRSF039144 1 112 2.6E-51 T 13-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THL1_RS07465 eb3e1e226a8b5a4b0961396ba75c31d3 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 13-09-2016 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 THL1_RS07465 eb3e1e226a8b5a4b0961396ba75c31d3 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 2.2E-40 T 13-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THL1_RS07465 eb3e1e226a8b5a4b0961396ba75c31d3 112 SUPERFAMILY SSF54913 1 112 2.45E-43 T 13-09-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta THL1_RS07465 eb3e1e226a8b5a4b0961396ba75c31d3 112 PANTHER PTHR30115:SF12 1 112 2.1E-63 T 13-09-2016 THL1_RS07465 eb3e1e226a8b5a4b0961396ba75c31d3 112 PRINTS PR00340 P-II protein signature 23 41 1.2E-37 T 13-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THL1_RS07465 eb3e1e226a8b5a4b0961396ba75c31d3 112 PRINTS PR00340 P-II protein signature 83 103 1.2E-37 T 13-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THL1_RS07465 eb3e1e226a8b5a4b0961396ba75c31d3 112 PRINTS PR00340 P-II protein signature 2 17 1.2E-37 T 13-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THL1_RS07465 eb3e1e226a8b5a4b0961396ba75c31d3 112 PRINTS PR00340 P-II protein signature 52 75 1.2E-37 T 13-09-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THL1_RS07465 eb3e1e226a8b5a4b0961396ba75c31d3 112 Gene3D G3DSA:3.30.70.120 1 112 8.8E-47 T 13-09-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THL1_RS10660 56cc25eff7a46e244431706cf91f7e0c 245 PANTHER PTHR11904:SF1 5 245 6.9E-82 T 13-09-2016 THL1_RS10660 56cc25eff7a46e244431706cf91f7e0c 245 Pfam PF01048 Phosphorylase superfamily 4 243 1.6E-42 T 13-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 THL1_RS10660 56cc25eff7a46e244431706cf91f7e0c 245 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 50 90 - T 13-09-2016 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 THL1_RS10660 56cc25eff7a46e244431706cf91f7e0c 245 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 244 1.4E-89 T 13-09-2016 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 THL1_RS10660 56cc25eff7a46e244431706cf91f7e0c 245 SUPERFAMILY SSF53167 3 244 2.09E-77 T 13-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 THL1_RS10660 56cc25eff7a46e244431706cf91f7e0c 245 PANTHER PTHR11904 5 245 6.9E-82 T 13-09-2016 IPR001369 PNP/MTAP phosphorylase THL1_RS10660 56cc25eff7a46e244431706cf91f7e0c 245 Gene3D G3DSA:3.40.50.1580 4 244 1.0E-71 T 13-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 THL1_RS10660 56cc25eff7a46e244431706cf91f7e0c 245 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 245 32.886 T 13-09-2016 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 THL1_RS13235 f6d0e22a5443a5907eaa3b8b4b1936d5 122 Pfam PF16703 Domain of unknown function (DUF5064) 1 117 9.1E-45 T 13-09-2016 IPR032024 Protein of unknown function DUF5064 THL1_RS11845 fb3a28e7f006f37dfb61a8cf206d9449 205 Pfam PF12710 haloacid dehalogenase-like hydrolase 66 160 3.3E-9 T 13-09-2016 THL1_RS11845 fb3a28e7f006f37dfb61a8cf206d9449 205 SUPERFAMILY SSF56784 2 183 2.36E-43 T 13-09-2016 IPR023214 HAD-like domain THL1_RS11845 fb3a28e7f006f37dfb61a8cf206d9449 205 Gene3D G3DSA:3.40.50.1000 126 176 1.4E-6 T 13-09-2016 IPR023214 HAD-like domain THL1_RS11845 fb3a28e7f006f37dfb61a8cf206d9449 205 Gene3D G3DSA:3.90.1470.10 13 125 6.6E-46 T 13-09-2016 THL1_RS11845 fb3a28e7f006f37dfb61a8cf206d9449 205 TIGRFAM TIGR02137 HSK-PSP: phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein 2 203 7.7E-120 T 13-09-2016 IPR011863 Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|UniPathway: UPA00135 THL1_RS05155 8d793e6b89198dbe02ea67bde96e129e 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 224 7.8E-19 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS05155 8d793e6b89198dbe02ea67bde96e129e 231 SUPERFAMILY SSF161098 12 211 1.57E-35 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS05155 8d793e6b89198dbe02ea67bde96e129e 231 Gene3D G3DSA:1.10.3720.10 11 224 4.8E-38 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS05155 8d793e6b89198dbe02ea67bde96e129e 231 PANTHER PTHR30614 1 231 1.9E-65 T 13-09-2016 THL1_RS05155 8d793e6b89198dbe02ea67bde96e129e 231 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 120 2.9E-19 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS10945 52d53ff24ef27d176dd860060006737b 313 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 2 177 5.1E-31 T 13-09-2016 IPR000477 Reverse transcriptase domain THL1_RS10945 52d53ff24ef27d176dd860060006737b 313 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 93 106 2.4E-5 T 13-09-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THL1_RS10945 52d53ff24ef27d176dd860060006737b 313 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 35 53 2.4E-5 T 13-09-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THL1_RS10945 52d53ff24ef27d176dd860060006737b 313 PANTHER PTHR19446 1 213 2.5E-39 T 13-09-2016 THL1_RS10945 52d53ff24ef27d176dd860060006737b 313 PANTHER PTHR19446:SF107 1 213 2.5E-39 T 13-09-2016 THL1_RS10945 52d53ff24ef27d176dd860060006737b 313 SUPERFAMILY SSF56672 2 255 1.08E-33 T 13-09-2016 THL1_RS10945 52d53ff24ef27d176dd860060006737b 313 Pfam PF08388 Group II intron, maturase-specific domain 195 270 1.3E-15 T 13-09-2016 IPR013597 Group II intron, maturase-specific THL1_RS10720 675aad8ff1427641d35ddf6c51ad9912 338 SUPERFAMILY SSF143631 28 332 6.28E-94 T 13-09-2016 IPR003374 ApbE-like domain THL1_RS10720 675aad8ff1427641d35ddf6c51ad9912 338 PIRSF PIRSF006268 4 335 1.2E-84 T 13-09-2016 IPR024932 Flavin transferase ApbE GO:0017013 THL1_RS10720 675aad8ff1427641d35ddf6c51ad9912 338 Pfam PF02424 ApbE family 33 313 1.2E-79 T 13-09-2016 IPR024932 Flavin transferase ApbE GO:0017013 THL1_RS10720 675aad8ff1427641d35ddf6c51ad9912 338 PANTHER PTHR30040:SF3 8 337 4.4E-146 T 13-09-2016 THL1_RS10720 675aad8ff1427641d35ddf6c51ad9912 338 PANTHER PTHR30040 8 337 4.4E-146 T 13-09-2016 THL1_RS06010 0f6b1fb5e49ff61a889f0b816fcec442 382 PANTHER PTHR11751 9 382 2.6E-147 T 13-09-2016 THL1_RS06010 0f6b1fb5e49ff61a889f0b816fcec442 382 Gene3D G3DSA:3.90.1150.10 250 380 6.0E-23 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS06010 0f6b1fb5e49ff61a889f0b816fcec442 382 PANTHER PTHR11751:SF301 9 382 2.6E-147 T 13-09-2016 THL1_RS06010 0f6b1fb5e49ff61a889f0b816fcec442 382 SUPERFAMILY SSF53383 3 380 4.57E-103 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS06010 0f6b1fb5e49ff61a889f0b816fcec442 382 Pfam PF00155 Aminotransferase class I and II 27 379 1.5E-60 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS06010 0f6b1fb5e49ff61a889f0b816fcec442 382 Gene3D G3DSA:3.40.640.10 39 249 1.5E-71 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 Gene3D G3DSA:3.40.50.300 348 507 4.2E-46 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 Gene3D G3DSA:3.30.56.50 2 51 1.4E-20 T 13-09-2016 THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 61 95 4.9E-11 T 13-09-2016 IPR013575 Initiation factor 2 associated domain, bacterial THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 SUPERFAMILY SSF52540 340 516 2.28E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 Gene3D G3DSA:2.40.30.10 519 612 1.8E-26 T 13-09-2016 THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 SUPERFAMILY SSF52156 626 755 1.31E-34 T 13-09-2016 IPR023115 Translation initiation factor IF- 2, domain 3 THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 351 507 3.1E-31 T 13-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 Pfam PF00009 Elongation factor Tu GTP binding domain 352 509 2.8E-34 T 13-09-2016 THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 SUPERFAMILY SSF50447 521 603 1.56E-26 T 13-09-2016 IPR009000 Translation protein, beta-barrel domain THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 846 17.379 T 13-09-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 Pfam PF11987 Translation-initiation factor 2 634 738 4.0E-34 T 13-09-2016 IPR023115 Translation initiation factor IF- 2, domain 3 THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 Gene3D G3DSA:2.40.30.10 750 846 3.3E-37 T 13-09-2016 THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 267 848 2.1E-265 T 13-09-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 SUPERFAMILY SSF46955 3 51 1.3E-9 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 PANTHER PTHR23115 701 846 2.5E-207 T 13-09-2016 THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 PANTHER PTHR23115 329 676 2.5E-207 T 13-09-2016 THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 Gene3D G3DSA:3.40.50.10050 648 727 3.0E-21 T 13-09-2016 IPR023115 Translation initiation factor IF- 2, domain 3 THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 ProSitePatterns PS01176 Initiation factor 2 signature. 799 821 - T 13-09-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 PANTHER PTHR23115:SF184 701 846 2.5E-207 T 13-09-2016 THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 PANTHER PTHR23115:SF184 329 676 2.5E-207 T 13-09-2016 THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 273 323 1.0E-14 T 13-09-2016 IPR006847 Translation initiation factor IF-2, N-terminal THL1_RS24395 ac79590cba45529ef71280e584d5b076 848 SUPERFAMILY SSF50447 750 846 1.92E-32 T 13-09-2016 IPR009000 Translation protein, beta-barrel domain THL1_RS07260 fdb7dcc24245209759a0b3050420ffdc 341 Gene3D G3DSA:3.40.190.10 129 284 9.4E-34 T 13-09-2016 THL1_RS07260 fdb7dcc24245209759a0b3050420ffdc 341 SUPERFAMILY SSF53850 29 339 1.09E-65 T 13-09-2016 THL1_RS07260 fdb7dcc24245209759a0b3050420ffdc 341 PANTHER PTHR30222 8 338 1.0E-79 T 13-09-2016 THL1_RS07260 fdb7dcc24245209759a0b3050420ffdc 341 Gene3D G3DSA:3.40.190.10 29 118 1.2E-6 T 13-09-2016 THL1_RS07260 fdb7dcc24245209759a0b3050420ffdc 341 Pfam PF13416 Bacterial extracellular solute-binding protein 46 297 1.2E-36 T 13-09-2016 THL1_RS07260 fdb7dcc24245209759a0b3050420ffdc 341 PANTHER PTHR30222:SF2 8 338 1.0E-79 T 13-09-2016 THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 Pfam PF00990 Diguanylate cyclase, GGDEF domain 944 1105 2.2E-50 T 13-09-2016 IPR000160 GGDEF domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SUPERFAMILY SSF141868 1124 1370 1.03E-93 T 13-09-2016 IPR001633 EAL domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 PANTHER PTHR10799 788 1219 5.0E-83 T 13-09-2016 THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 Pfam PF08447 PAS fold 577 665 9.7E-16 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 Gene3D G3DSA:3.30.70.270 945 1117 1.0E-58 T 13-09-2016 THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 941 1107 3.5E-42 T 13-09-2016 IPR000160 GGDEF domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SUPERFAMILY SSF55785 535 669 3.32E-18 T 13-09-2016 IPR000014 PAS domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SMART SM00086 891 933 1.6E-4 T 13-09-2016 IPR001610 PAC motif THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SMART SM00086 152 196 360.0 T 13-09-2016 IPR001610 PAC motif THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SMART SM00086 769 811 0.0016 T 13-09-2016 IPR001610 PAC motif THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SMART SM00086 338 379 70.0 T 13-09-2016 IPR001610 PAC motif THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SMART SM00086 628 671 2.5E-7 T 13-09-2016 IPR001610 PAC motif THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 Gene3D G3DSA:3.30.450.20 535 672 9.8E-28 T 13-09-2016 THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 Gene3D G3DSA:3.30.450.20 372 421 2.8E-4 T 13-09-2016 THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SMART SM00091 819 884 6.4E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SMART SM00091 683 747 1.0 T 13-09-2016 IPR000014 PAS domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SMART SM00091 550 619 0.0022 T 13-09-2016 IPR000014 PAS domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SMART SM00091 271 337 1.3 T 13-09-2016 IPR000014 PAS domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SUPERFAMILY SSF55785 446 545 4.01E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 679 816 8.6E-10 T 13-09-2016 IPR000014 PAS domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 547 676 7.3E-11 T 13-09-2016 IPR000014 PAS domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 823 939 1.4E-18 T 13-09-2016 IPR000014 PAS domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 Pfam PF13426 PAS domain 831 932 9.3E-15 T 13-09-2016 IPR000014 PAS domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 Pfam PF13426 PAS domain 695 810 6.8E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 Gene3D G3DSA:3.30.450.20 268 371 9.2E-11 T 13-09-2016 THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SMART SM00267 933 1109 2.9E-68 T 13-09-2016 IPR000160 GGDEF domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 PANTHER PTHR10799:SF774 788 1219 5.0E-83 T 13-09-2016 THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 PANTHER PTHR10799:SF774 1 7 5.0E-83 T 13-09-2016 THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 Gene3D G3DSA:3.30.450.20 442 534 8.2E-9 T 13-09-2016 THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 PANTHER PTHR10799 1 7 5.0E-83 T 13-09-2016 THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 Gene3D G3DSA:3.30.450.20 809 927 1.2E-22 T 13-09-2016 THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SMART SM00052 1119 1365 7.5E-128 T 13-09-2016 IPR001633 EAL domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 Pfam PF13188 PAS domain 286 326 0.13 T 13-09-2016 IPR000014 PAS domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 Pfam PF13188 PAS domain 392 482 0.058 T 13-09-2016 IPR000014 PAS domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SUPERFAMILY SSF55073 949 1110 1.23E-49 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 Gene3D G3DSA:3.20.20.450 1122 1370 3.3E-106 T 13-09-2016 IPR001633 EAL domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SUPERFAMILY SSF55785 260 377 6.81E-9 T 13-09-2016 IPR000014 PAS domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 Gene3D G3DSA:3.30.450.20 673 808 1.3E-15 T 13-09-2016 THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SUPERFAMILY SSF55785 831 941 6.13E-22 T 13-09-2016 IPR000014 PAS domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 Pfam PF00563 EAL domain 1125 1360 1.0E-76 T 13-09-2016 IPR001633 EAL domain THL1_RS04750 67e5f4d26136cccd7f6c6094b8c5be17 1379 SUPERFAMILY SSF55785 668 809 2.58E-14 T 13-09-2016 IPR000014 PAS domain THL1_RS23435 6adcd33cf26fdec87c3a3f2c8f590e99 243 Gene3D G3DSA:2.30.110.10 4 147 1.7E-54 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS23435 6adcd33cf26fdec87c3a3f2c8f590e99 243 Gene3D G3DSA:3.20.180.10 154 238 2.4E-29 T 13-09-2016 IPR019595 Domain of unknown function DUF2470 THL1_RS23435 6adcd33cf26fdec87c3a3f2c8f590e99 243 SUPERFAMILY SSF50475 3 235 2.95E-54 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS23435 6adcd33cf26fdec87c3a3f2c8f590e99 243 PANTHER PTHR13343 5 243 6.1E-51 T 13-09-2016 THL1_RS23435 6adcd33cf26fdec87c3a3f2c8f590e99 243 PANTHER PTHR13343:SF4 5 243 6.1E-51 T 13-09-2016 THL1_RS23435 6adcd33cf26fdec87c3a3f2c8f590e99 243 Pfam PF10615 Protein of unknown function (DUF2470) 161 229 4.2E-14 T 13-09-2016 IPR019595 Domain of unknown function DUF2470 THL1_RS23435 6adcd33cf26fdec87c3a3f2c8f590e99 243 Pfam PF13883 Pyridoxamine 5'-phosphate oxidase 4 146 4.6E-16 T 13-09-2016 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 PANTHER PTHR13847:SF189 120 222 3.5E-152 T 13-09-2016 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 PANTHER PTHR13847:SF189 616 928 3.5E-152 T 13-09-2016 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 SUPERFAMILY SSF101790 906 1003 6.38E-18 T 13-09-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 PANTHER PTHR13847 120 222 3.5E-152 T 13-09-2016 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 PANTHER PTHR13847 616 928 3.5E-152 T 13-09-2016 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 Gene3D G3DSA:3.30.1360.120 756 862 3.2E-25 T 13-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 Gene3D G3DSA:3.50.50.60 164 312 2.5E-33 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 Gene3D G3DSA:3.50.50.60 359 482 2.5E-33 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 172 472 1.8E-13 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 Gene3D G3DSA:3.30.70.1400 673 749 2.4E-23 T 13-09-2016 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 TIGRFAM TIGR01372 soxA: sarcosine oxidase, alpha subunit family 2 1005 0.0 T 13-09-2016 IPR006277 Sarcosine oxidase, alpha subunit GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 SUPERFAMILY SSF103025 614 896 1.13E-92 T 13-09-2016 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 SUPERFAMILY SSF51905 167 471 3.15E-34 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 301 2.9E-11 T 13-09-2016 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 450 472 2.9E-11 T 13-09-2016 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 192 2.9E-11 T 13-09-2016 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 Gene3D G3DSA:2.40.30.110 910 1005 9.4E-20 T 13-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 PIRSF PIRSF037980 1 1005 0.0 T 13-09-2016 IPR006277 Sarcosine oxidase, alpha subunit GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 373 389 3.7E-13 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 284 292 3.7E-13 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 460 478 3.7E-13 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 172 194 3.7E-13 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 Pfam PF01571 Aminomethyltransferase folate-binding domain 620 885 7.5E-75 T 13-09-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 17 102 2.6E-23 T 13-09-2016 THL1_RS01990 c6e58a1afceb65f57447081d58e7a22c 1005 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 907 990 1.4E-8 T 13-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS22435 16c707e661d5e2a1465968f5b7d193e4 301 SUPERFAMILY SSF103481 41 144 1.57E-8 T 13-09-2016 THL1_RS22435 16c707e661d5e2a1465968f5b7d193e4 301 Pfam PF00892 EamA-like transporter family 7 141 1.1E-16 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS22435 16c707e661d5e2a1465968f5b7d193e4 301 Pfam PF00892 EamA-like transporter family 150 282 1.3E-17 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS22435 16c707e661d5e2a1465968f5b7d193e4 301 PANTHER PTHR12715:SF8 1 289 2.6E-69 T 13-09-2016 THL1_RS22435 16c707e661d5e2a1465968f5b7d193e4 301 SUPERFAMILY SSF103481 190 288 3.14E-12 T 13-09-2016 THL1_RS22435 16c707e661d5e2a1465968f5b7d193e4 301 PANTHER PTHR12715 1 289 2.6E-69 T 13-09-2016 THL1_RS05935 e0aedb0b2d1a999ae3fb3a8ede5e12c9 128 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 125 5.7E-70 T 13-09-2016 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 THL1_RS05935 e0aedb0b2d1a999ae3fb3a8ede5e12c9 128 Gene3D G3DSA:3.90.1010.10 2 125 1.2E-55 T 13-09-2016 THL1_RS05935 e0aedb0b2d1a999ae3fb3a8ede5e12c9 128 Pfam PF01592 NifU-like N terminal domain 3 125 8.1E-58 T 13-09-2016 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 THL1_RS05935 e0aedb0b2d1a999ae3fb3a8ede5e12c9 128 SUPERFAMILY SSF82649 2 125 9.42E-49 T 13-09-2016 THL1_RS05935 e0aedb0b2d1a999ae3fb3a8ede5e12c9 128 PANTHER PTHR10093 1 128 8.9E-100 T 13-09-2016 THL1_RS05935 e0aedb0b2d1a999ae3fb3a8ede5e12c9 128 PANTHER PTHR10093:SF3 1 128 8.9E-100 T 13-09-2016 THL1_RS10855 e2363ac5f7432802bc405396db481437 122 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 10 82 6.9E-8 T 13-09-2016 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 UniPathway: UPA00223 THL1_RS10855 e2363ac5f7432802bc405396db481437 122 PIRSF PIRSF000169 1 122 5.1E-44 T 13-09-2016 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 UniPathway: UPA00223 THL1_RS10855 e2363ac5f7432802bc405396db481437 122 PANTHER PTHR38689 2 122 9.4E-55 T 13-09-2016 THL1_RS10855 e2363ac5f7432802bc405396db481437 122 SUPERFAMILY SSF81343 4 122 5.45E-28 T 13-09-2016 THL1_RS10855 e2363ac5f7432802bc405396db481437 122 Gene3D G3DSA:1.20.1300.10 1 122 1.9E-36 T 13-09-2016 THL1_RS10855 e2363ac5f7432802bc405396db481437 122 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 10 120 1.3E-34 T 13-09-2016 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 UniPathway: UPA00223 THL1_RS10855 e2363ac5f7432802bc405396db481437 122 PANTHER PTHR38689:SF1 2 122 9.4E-55 T 13-09-2016 THL1_RS12740 4a869f6a79ef776486531109e7b76731 278 SUPERFAMILY SSF88713 5 272 1.95E-55 T 13-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THL1_RS12740 4a869f6a79ef776486531109e7b76731 278 Pfam PF01522 Polysaccharide deacetylase 14 158 3.8E-17 T 13-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 THL1_RS12740 4a869f6a79ef776486531109e7b76731 278 Gene3D G3DSA:3.20.20.370 6 272 2.6E-74 T 13-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 THL1_RS12740 4a869f6a79ef776486531109e7b76731 278 PANTHER PTHR10587:SF74 17 176 3.4E-23 T 13-09-2016 THL1_RS12740 4a869f6a79ef776486531109e7b76731 278 PANTHER PTHR10587 17 176 3.4E-23 T 13-09-2016 THL1_RS01600 55a6062d57b1670d5add64a3b5397e94 281 PANTHER PTHR21091:SF31 136 271 2.0E-42 T 13-09-2016 THL1_RS01600 55a6062d57b1670d5add64a3b5397e94 281 PANTHER PTHR21091 136 271 2.0E-42 T 13-09-2016 THL1_RS01600 55a6062d57b1670d5add64a3b5397e94 281 SUPERFAMILY SSF51730 4 279 4.71E-94 T 13-09-2016 IPR029041 FAD-linked oxidoreductase-like THL1_RS01600 55a6062d57b1670d5add64a3b5397e94 281 Pfam PF02219 Methylenetetrahydrofolate reductase 4 277 1.4E-89 T 13-09-2016 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 THL1_RS01600 55a6062d57b1670d5add64a3b5397e94 281 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 7 277 9.1E-101 T 13-09-2016 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 THL1_RS01600 55a6062d57b1670d5add64a3b5397e94 281 Gene3D G3DSA:3.20.20.220 3 279 6.1E-106 T 13-09-2016 IPR029041 FAD-linked oxidoreductase-like THL1_RS01980 9fc76ae2ee61d9869da471f3f747927e 416 PANTHER PTHR13847:SF44 11 401 1.2E-67 T 13-09-2016 THL1_RS01980 9fc76ae2ee61d9869da471f3f747927e 416 SUPERFAMILY SSF51905 33 254 3.56E-48 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01980 9fc76ae2ee61d9869da471f3f747927e 416 SUPERFAMILY SSF51905 344 403 3.56E-48 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01980 9fc76ae2ee61d9869da471f3f747927e 416 PANTHER PTHR13847 11 401 1.2E-67 T 13-09-2016 THL1_RS01980 9fc76ae2ee61d9869da471f3f747927e 416 Gene3D G3DSA:3.30.9.10 254 343 3.2E-10 T 13-09-2016 THL1_RS01980 9fc76ae2ee61d9869da471f3f747927e 416 Gene3D G3DSA:3.30.9.10 116 174 3.2E-10 T 13-09-2016 THL1_RS01980 9fc76ae2ee61d9869da471f3f747927e 416 Gene3D G3DSA:3.50.50.60 344 402 5.6E-53 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01980 9fc76ae2ee61d9869da471f3f747927e 416 Gene3D G3DSA:3.50.50.60 175 253 5.6E-53 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01980 9fc76ae2ee61d9869da471f3f747927e 416 Gene3D G3DSA:3.50.50.60 18 111 5.6E-53 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01980 9fc76ae2ee61d9869da471f3f747927e 416 TIGRFAM TIGR01373 soxB: sarcosine oxidase, beta subunit family 3 408 1.9E-227 T 13-09-2016 IPR006278 Sarcosine oxidase subunit beta GO:0008115|GO:0046653|GO:0055114 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 THL1_RS01980 9fc76ae2ee61d9869da471f3f747927e 416 Pfam PF01266 FAD dependent oxidoreductase 34 380 1.3E-54 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS21685 3d00b7ca172cfc000b8177a4f8292f04 511 Pfam PF00158 Sigma-54 interaction domain 202 369 5.3E-64 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS21685 3d00b7ca172cfc000b8177a4f8292f04 511 Gene3D G3DSA:1.10.8.60 376 445 6.4E-20 T 13-09-2016 THL1_RS21685 3d00b7ca172cfc000b8177a4f8292f04 511 Gene3D G3DSA:1.10.10.60 457 510 5.1E-19 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21685 3d00b7ca172cfc000b8177a4f8292f04 511 SUPERFAMILY SSF52540 203 445 3.03E-67 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21685 3d00b7ca172cfc000b8177a4f8292f04 511 Gene3D G3DSA:3.30.450.20 76 134 1.3E-6 T 13-09-2016 THL1_RS21685 3d00b7ca172cfc000b8177a4f8292f04 511 Gene3D G3DSA:3.40.50.300 200 375 3.2E-54 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21685 3d00b7ca172cfc000b8177a4f8292f04 511 SUPERFAMILY SSF46689 457 510 8.69E-7 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21685 3d00b7ca172cfc000b8177a4f8292f04 511 PANTHER PTHR32071:SF3 1 511 2.6E-171 T 13-09-2016 THL1_RS21685 3d00b7ca172cfc000b8177a4f8292f04 511 TIGRFAM TIGR04381 HTH_TypR: TyrR family helix-turn-helix domain 463 510 2.0E-23 T 13-09-2016 IPR030828 TyrR family, helix-turn-helix domain GO:0003677 THL1_RS21685 3d00b7ca172cfc000b8177a4f8292f04 511 SMART SM00382 222 370 3.9E-8 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS21685 3d00b7ca172cfc000b8177a4f8292f04 511 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 226 239 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS21685 3d00b7ca172cfc000b8177a4f8292f04 511 PANTHER PTHR32071 1 511 2.6E-171 T 13-09-2016 THL1_RS21685 3d00b7ca172cfc000b8177a4f8292f04 511 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 289 304 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS05385 003c52c518fd75918f460be1f84f8dd9 174 PANTHER PTHR21485 6 164 1.6E-53 T 13-09-2016 THL1_RS05385 003c52c518fd75918f460be1f84f8dd9 174 Pfam PF08282 haloacid dehalogenase-like hydrolase 87 150 9.9E-8 T 13-09-2016 IPR023214 HAD-like domain THL1_RS05385 003c52c518fd75918f460be1f84f8dd9 174 SUPERFAMILY SSF56784 9 166 6.96E-41 T 13-09-2016 IPR023214 HAD-like domain THL1_RS05385 003c52c518fd75918f460be1f84f8dd9 174 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 12 163 1.0E-47 T 13-09-2016 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 THL1_RS05385 003c52c518fd75918f460be1f84f8dd9 174 Gene3D G3DSA:3.40.50.1000 3 169 1.2E-45 T 13-09-2016 IPR023214 HAD-like domain THL1_RS05385 003c52c518fd75918f460be1f84f8dd9 174 PIRSF PIRSF006118 1 174 7.6E-70 T 13-09-2016 IPR010023 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase GO:0019143 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 THL1_RS04045 c419e483cede6eabf003163392878175 144 SMART SM00226 3 143 7.6E-52 T 13-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily THL1_RS04045 c419e483cede6eabf003163392878175 144 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 140 7.0E-42 T 13-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily THL1_RS04045 c419e483cede6eabf003163392878175 144 PANTHER PTHR11717 1 142 1.9E-38 T 13-09-2016 THL1_RS04045 c419e483cede6eabf003163392878175 144 PANTHER PTHR11717:SF20 1 142 1.9E-38 T 13-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THL1_RS04045 c419e483cede6eabf003163392878175 144 SUPERFAMILY SSF52788 1 144 8.5E-44 T 13-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily THL1_RS04045 c419e483cede6eabf003163392878175 144 Gene3D G3DSA:3.40.50.270 2 144 8.4E-47 T 13-09-2016 THL1_RS04045 c419e483cede6eabf003163392878175 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 43 59 5.7E-28 T 13-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THL1_RS04045 c419e483cede6eabf003163392878175 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 99 112 5.7E-28 T 13-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THL1_RS04045 c419e483cede6eabf003163392878175 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 115 130 5.7E-28 T 13-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THL1_RS04045 c419e483cede6eabf003163392878175 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 5 22 5.7E-28 T 13-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THL1_RS04045 c419e483cede6eabf003163392878175 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 77 92 5.7E-28 T 13-09-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THL1_RS02545 01ff34c68f2785dfd76e8b4340100a74 341 Pfam PF00814 Glycoprotease family 24 311 3.8E-101 T 13-09-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THL1_RS02545 01ff34c68f2785dfd76e8b4340100a74 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 7.8E-52 T 13-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THL1_RS02545 01ff34c68f2785dfd76e8b4340100a74 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 7.8E-52 T 13-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THL1_RS02545 01ff34c68f2785dfd76e8b4340100a74 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 7.8E-52 T 13-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THL1_RS02545 01ff34c68f2785dfd76e8b4340100a74 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 7.8E-52 T 13-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THL1_RS02545 01ff34c68f2785dfd76e8b4340100a74 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 7.8E-52 T 13-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THL1_RS02545 01ff34c68f2785dfd76e8b4340100a74 341 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 7.8E-52 T 13-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THL1_RS02545 01ff34c68f2785dfd76e8b4340100a74 341 PANTHER PTHR11735:SF6 1 340 1.4E-164 T 13-09-2016 THL1_RS02545 01ff34c68f2785dfd76e8b4340100a74 341 PANTHER PTHR11735 1 340 1.4E-164 T 13-09-2016 THL1_RS02545 01ff34c68f2785dfd76e8b4340100a74 341 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 317 3.8E-133 T 13-09-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THL1_RS02545 01ff34c68f2785dfd76e8b4340100a74 341 SUPERFAMILY SSF53067 3 122 3.04E-32 T 13-09-2016 THL1_RS02545 01ff34c68f2785dfd76e8b4340100a74 341 Gene3D G3DSA:3.30.420.40 1 159 7.3E-50 T 13-09-2016 THL1_RS02545 01ff34c68f2785dfd76e8b4340100a74 341 SUPERFAMILY SSF53067 101 313 1.43E-43 T 13-09-2016 THL1_RS02545 01ff34c68f2785dfd76e8b4340100a74 341 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 310 2.3E-118 T 13-09-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THL1_RS02545 01ff34c68f2785dfd76e8b4340100a74 341 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 335 62.615 T 13-09-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THL1_RS13885 ad9a9b4038f9396adb22c9102f2368d7 282 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 3 274 6.9E-61 T 13-09-2016 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: REACT_13 THL1_RS13885 ad9a9b4038f9396adb22c9102f2368d7 282 Gene3D G3DSA:3.60.130.10 1 282 1.4E-91 T 13-09-2016 THL1_RS13885 ad9a9b4038f9396adb22c9102f2368d7 282 SUPERFAMILY SSF51197 2 282 4.26E-88 T 13-09-2016 THL1_RS13885 ad9a9b4038f9396adb22c9102f2368d7 282 PANTHER PTHR30468 1 282 3.7E-73 T 13-09-2016 THL1_RS27415 c5b26949bcd5f43f03b68a4e4800c78a 156 Pfam PF04353 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ 1 145 1.2E-53 T 13-09-2016 IPR007448 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GO:0006355 THL1_RS27415 c5b26949bcd5f43f03b68a4e4800c78a 156 PIRSF PIRSF016548 1 154 1.3E-61 T 13-09-2016 IPR007448 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ GO:0006355 THL1_RS02785 9bdb35fd158be88bd9d2f788910adc38 694 SUPERFAMILY SSF53067 267 315 2.7E-5 T 13-09-2016 THL1_RS02785 9bdb35fd158be88bd9d2f788910adc38 694 SUPERFAMILY SSF53067 6 81 2.7E-5 T 13-09-2016 THL1_RS02785 9bdb35fd158be88bd9d2f788910adc38 694 Pfam PF01968 Hydantoinase/oxoprolinase 210 497 2.3E-86 T 13-09-2016 IPR002821 Hydantoinase/oxoprolinase GO:0016787 THL1_RS02785 9bdb35fd158be88bd9d2f788910adc38 694 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 6 188 2.4E-41 T 13-09-2016 IPR008040 Hydantoinaseoxoprolinase, N-terminal THL1_RS02785 9bdb35fd158be88bd9d2f788910adc38 694 PANTHER PTHR11365 1 680 4.1E-166 T 13-09-2016 THL1_RS04055 07abe4e5a29ca87a7ec69c3fa8295170 175 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 37.031 T 13-09-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 THL1_RS04055 07abe4e5a29ca87a7ec69c3fa8295170 175 PANTHER PTHR10286 6 175 1.8E-72 T 13-09-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 THL1_RS04055 07abe4e5a29ca87a7ec69c3fa8295170 175 Gene3D G3DSA:3.90.80.10 3 175 2.0E-60 T 13-09-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 THL1_RS04055 07abe4e5a29ca87a7ec69c3fa8295170 175 Pfam PF00719 Inorganic pyrophosphatase 18 173 8.7E-53 T 13-09-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 THL1_RS04055 07abe4e5a29ca87a7ec69c3fa8295170 175 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 13-09-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 THL1_RS04055 07abe4e5a29ca87a7ec69c3fa8295170 175 SUPERFAMILY SSF50324 3 175 4.58E-68 T 13-09-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 THL1_RS07985 30652f92ece86d3a82a4d7e98e2c7f2a 281 SUPERFAMILY SSF56317 5 275 3.92E-69 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS07985 30652f92ece86d3a82a4d7e98e2c7f2a 281 Gene3D G3DSA:3.60.110.10 5 275 3.2E-74 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS07985 30652f92ece86d3a82a4d7e98e2c7f2a 281 PANTHER PTHR23088:SF11 4 276 2.0E-83 T 13-09-2016 THL1_RS07985 30652f92ece86d3a82a4d7e98e2c7f2a 281 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 147 167 - T 13-09-2016 IPR001110 Uncharacterised protein family UPF0012, conserved site THL1_RS07985 30652f92ece86d3a82a4d7e98e2c7f2a 281 PANTHER PTHR23088 4 276 2.0E-83 T 13-09-2016 THL1_RS07985 30652f92ece86d3a82a4d7e98e2c7f2a 281 Pfam PF00795 Carbon-nitrogen hydrolase 8 255 1.0E-45 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS00925 3166de5ca976458be341769ed592c6ac 261 PANTHER PTHR30151 6 261 1.2E-183 T 13-09-2016 THL1_RS00925 3166de5ca976458be341769ed592c6ac 261 Gene3D G3DSA:1.10.3720.10 53 247 2.0E-26 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00925 3166de5ca976458be341769ed592c6ac 261 SUPERFAMILY SSF161098 54 235 6.67E-35 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00925 3166de5ca976458be341769ed592c6ac 261 PANTHER PTHR30151:SF22 6 261 1.2E-183 T 13-09-2016 THL1_RS00925 3166de5ca976458be341769ed592c6ac 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 244 1.0E-26 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS17900 02fb09e8f2864a773a81b35f6f81f336 147 Pfam PF00075 RNase H 5 141 4.8E-51 T 13-09-2016 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 THL1_RS17900 02fb09e8f2864a773a81b35f6f81f336 147 PANTHER PTHR10642 2 143 5.6E-61 T 13-09-2016 THL1_RS17900 02fb09e8f2864a773a81b35f6f81f336 147 Gene3D G3DSA:3.30.420.10 5 143 3.1E-63 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS17900 02fb09e8f2864a773a81b35f6f81f336 147 SUPERFAMILY SSF53098 3 142 1.64E-59 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS17900 02fb09e8f2864a773a81b35f6f81f336 147 Hamap MF_00042 Ribonuclease H [rnhA]. 2 147 34.299 T 13-09-2016 IPR022892 Ribonuclease H GO:0004523 THL1_RS06310 021afb5129cfdb142fed10ab36b5f731 493 SUPERFAMILY SSF53448 285 360 1.8E-11 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS06310 021afb5129cfdb142fed10ab36b5f731 493 SUPERFAMILY SSF53448 150 254 1.8E-11 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS06310 021afb5129cfdb142fed10ab36b5f731 493 Pfam PF13641 Glycosyltransferase like family 2 86 342 4.6E-55 T 13-09-2016 THL1_RS06310 021afb5129cfdb142fed10ab36b5f731 493 ProDom PD339107 ALGINATE ALG8 BIOSYNTHESIS TRANSFERASE TRANSMEMBRANE MEMBRANE 2.4.1.- GLYCOSYL GLYCOSYLTRANSFERASE PRECURSOR 1 493 0.0 T 13-09-2016 THL1_RS12390 bf693ba401f5253a17fb3a2c568cce63 235 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 15 85 9.1E-20 T 13-09-2016 IPR007471 Arginine-tRNA-protein transferase, N-terminal GO:0004057|GO:0016598 THL1_RS12390 bf693ba401f5253a17fb3a2c568cce63 235 PANTHER PTHR21367 12 232 1.4E-79 T 13-09-2016 IPR030700 Arginine-tRNA-protein transferase THL1_RS12390 bf693ba401f5253a17fb3a2c568cce63 235 Hamap MF_00689 Putative arginyl-tRNA--protein transferase [ate]. 1 235 45.475 T 13-09-2016 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic THL1_RS12390 bf693ba401f5253a17fb3a2c568cce63 235 PIRSF PIRSF037208 1 235 1.1E-94 T 13-09-2016 IPR017138 Putative arginyl-tRNA--protein transferase, prokaryotic THL1_RS12390 bf693ba401f5253a17fb3a2c568cce63 235 SUPERFAMILY SSF55729 80 233 3.46E-25 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS12390 bf693ba401f5253a17fb3a2c568cce63 235 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 105 226 2.0E-39 T 13-09-2016 IPR007472 Arginine-tRNA-protein transferase, C-terminal GO:0004057|GO:0016598 THL1_RS11550 c4f85c43d8d5bc8bf23b804424e9395c 248 PANTHER PTHR11558 4 170 2.8E-14 T 13-09-2016 THL1_RS11550 c4f85c43d8d5bc8bf23b804424e9395c 248 SUPERFAMILY SSF53335 4 213 5.14E-40 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS11550 c4f85c43d8d5bc8bf23b804424e9395c 248 Gene3D G3DSA:3.40.50.150 5 232 9.2E-49 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS13880 61525248360a1e3648b9cda0e3c7085f 326 Gene3D G3DSA:3.20.20.120 272 314 2.3E-4 T 13-09-2016 IPR029065 Enolase C-terminal domain-like THL1_RS13880 61525248360a1e3648b9cda0e3c7085f 326 Gene3D G3DSA:3.40.50.720 149 258 6.1E-32 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS13880 61525248360a1e3648b9cda0e3c7085f 326 SUPERFAMILY SSF50129 2 146 1.47E-36 T 13-09-2016 IPR011032 GroES-like THL1_RS13880 61525248360a1e3648b9cda0e3c7085f 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 88 5.1E-9 T 13-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THL1_RS13880 61525248360a1e3648b9cda0e3c7085f 326 PANTHER PTHR11695:SF605 16 326 7.9E-122 T 13-09-2016 THL1_RS13880 61525248360a1e3648b9cda0e3c7085f 326 Gene3D G3DSA:3.90.180.10 2 148 5.1E-43 T 13-09-2016 IPR011032 GroES-like THL1_RS13880 61525248360a1e3648b9cda0e3c7085f 326 SMART SM00829 11 324 7.1E-37 T 13-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THL1_RS13880 61525248360a1e3648b9cda0e3c7085f 326 SUPERFAMILY SSF51735 115 266 1.87E-47 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS13880 61525248360a1e3648b9cda0e3c7085f 326 PANTHER PTHR11695 16 326 7.9E-122 T 13-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 THL1_RS13880 61525248360a1e3648b9cda0e3c7085f 326 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 142 163 - T 13-09-2016 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 THL1_RS13880 61525248360a1e3648b9cda0e3c7085f 326 Pfam PF00107 Zinc-binding dehydrogenase 153 259 3.2E-30 T 13-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THL1_RS21515 87caa77dfc83d58cca33e4c8559de1b6 242 PANTHER PTHR31527:SF0 12 242 6.4E-22 T 13-09-2016 THL1_RS21515 87caa77dfc83d58cca33e4c8559de1b6 242 PANTHER PTHR31527 12 242 6.4E-22 T 13-09-2016 THL1_RS21515 87caa77dfc83d58cca33e4c8559de1b6 242 Pfam PF09347 Domain of unknown function (DUF1989) 14 186 1.6E-52 T 13-09-2016 IPR018959 Domain of unknown function DUF1989 THL1_RS21515 87caa77dfc83d58cca33e4c8559de1b6 242 TIGRFAM TIGR03425 urea_degr_2: urea carboxylase-associated protein 2 11 241 1.1E-99 T 13-09-2016 IPR017792 Urea carboxylase-associated protein 2 THL1_RS21715 ad4146344fe32b08f14af566ee1ec356 324 Pfam PF04055 Radical SAM superfamily 94 253 1.5E-15 T 13-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 THL1_RS21715 ad4146344fe32b08f14af566ee1ec356 324 Gene3D G3DSA:3.20.20.70 55 316 6.0E-70 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS21715 ad4146344fe32b08f14af566ee1ec356 324 PANTHER PTHR10949 16 324 2.0E-165 T 13-09-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 THL1_RS21715 ad4146344fe32b08f14af566ee1ec356 324 SMART SM00729 87 293 7.9E-15 T 13-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THL1_RS21715 ad4146344fe32b08f14af566ee1ec356 324 PIRSF PIRSF005963 5 324 6.6E-126 T 13-09-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 THL1_RS21715 ad4146344fe32b08f14af566ee1ec356 324 SUPERFAMILY SSF102114 55 319 1.18E-66 T 13-09-2016 THL1_RS21715 ad4146344fe32b08f14af566ee1ec356 324 TIGRFAM TIGR00510 lipA: lipoyl synthase 35 316 3.5E-125 T 13-09-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 THL1_RS21715 ad4146344fe32b08f14af566ee1ec356 324 Hamap MF_00206 Lipoyl synthase [lipA]. 1 324 152.151 T 13-09-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 THL1_RS15315 8c88715e4b1e4c113d930f701f4f8a71 67 Pfam PF04328 Protein of unknown function (DUF466) 5 67 9.4E-29 T 13-09-2016 IPR007423 Protein of unknown function DUF466 THL1_RS15315 8c88715e4b1e4c113d930f701f4f8a71 67 PANTHER PTHR38453:SF2 1 67 4.2E-40 T 13-09-2016 THL1_RS15315 8c88715e4b1e4c113d930f701f4f8a71 67 PANTHER PTHR38453 1 67 4.2E-40 T 13-09-2016 THL1_RS02500 d69ba36fe9c4626680ef70fec7da5c8d 464 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 41 462 1.6E-138 T 13-09-2016 THL1_RS02500 d69ba36fe9c4626680ef70fec7da5c8d 464 Pfam PF04030 D-arabinono-1,4-lactone oxidase 208 458 2.3E-64 T 13-09-2016 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 THL1_RS02500 d69ba36fe9c4626680ef70fec7da5c8d 464 PANTHER PTHR13878 36 457 1.0E-95 T 13-09-2016 THL1_RS02500 d69ba36fe9c4626680ef70fec7da5c8d 464 Pfam PF01565 FAD binding domain 52 183 1.0E-22 T 13-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THL1_RS02500 d69ba36fe9c4626680ef70fec7da5c8d 464 PIRSF PIRSF000136 31 463 8.3E-89 T 13-09-2016 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 THL1_RS02500 d69ba36fe9c4626680ef70fec7da5c8d 464 PANTHER PTHR13878:SF5 36 457 1.0E-95 T 13-09-2016 THL1_RS02500 d69ba36fe9c4626680ef70fec7da5c8d 464 SUPERFAMILY SSF56176 36 211 7.01E-40 T 13-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THL1_RS02500 d69ba36fe9c4626680ef70fec7da5c8d 464 Gene3D G3DSA:3.30.43.10 40 104 9.0E-14 T 13-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 THL1_RS02500 d69ba36fe9c4626680ef70fec7da5c8d 464 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 5 35 2.9E-4 T 13-09-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THL1_RS02500 d69ba36fe9c4626680ef70fec7da5c8d 464 Gene3D G3DSA:3.30.465.10 105 211 8.6E-24 T 13-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THL1_RS24745 d25f541502dcfa9ba58f274577b62f10 134 Pfam PF10614 Type VIII secretion system (T8SS), CsgF protein 10 129 1.1E-32 T 13-09-2016 IPR018893 Type VIII secretion system, CsgF THL1_RS00475 9d4c3c9529aff9547a19d1fb75689ae4 133 SUPERFAMILY SSF51316 3 130 1.36E-43 T 13-09-2016 IPR011057 Mss4-like THL1_RS00475 9d4c3c9529aff9547a19d1fb75689ae4 133 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 27 114 5.5E-19 T 13-09-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801|UniPathway: UPA00562 THL1_RS00475 9d4c3c9529aff9547a19d1fb75689ae4 133 Gene3D G3DSA:3.90.1590.10 4 130 2.0E-38 T 13-09-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801|UniPathway: UPA00562 THL1_RS00475 9d4c3c9529aff9547a19d1fb75689ae4 133 PANTHER PTHR33337 5 131 1.5E-49 T 13-09-2016 THL1_RS00475 9d4c3c9529aff9547a19d1fb75689ae4 133 PANTHER PTHR33337:SF4 5 131 1.5E-49 T 13-09-2016 THL1_RS00965 b9e5417d91c609cf4bbaa5790f9b0319 250 PANTHER PTHR11922 85 246 2.8E-59 T 13-09-2016 THL1_RS00965 b9e5417d91c609cf4bbaa5790f9b0319 250 PANTHER PTHR11922 26 69 2.8E-59 T 13-09-2016 THL1_RS00965 b9e5417d91c609cf4bbaa5790f9b0319 250 SUPERFAMILY SSF52317 27 246 2.45E-41 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS00965 b9e5417d91c609cf4bbaa5790f9b0319 250 PANTHER PTHR11922:SF18 85 246 2.8E-59 T 13-09-2016 THL1_RS00965 b9e5417d91c609cf4bbaa5790f9b0319 250 PANTHER PTHR11922:SF18 26 69 2.8E-59 T 13-09-2016 THL1_RS00965 b9e5417d91c609cf4bbaa5790f9b0319 250 Gene3D G3DSA:3.40.50.880 5 247 1.1E-48 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS00965 b9e5417d91c609cf4bbaa5790f9b0319 250 Pfam PF07722 Peptidase C26 5 223 3.1E-74 T 13-09-2016 IPR011697 Peptidase C26 GO:0006541|GO:0016787 THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 Gene3D G3DSA:4.10.320.10 340 390 1.4E-20 T 13-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 PANTHER PTHR23151:SF68 402 648 5.0E-236 T 13-09-2016 THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 SUPERFAMILY SSF52777 407 648 7.12E-81 T 13-09-2016 THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 Pfam PF00364 Biotin-requiring enzyme 111 182 9.6E-21 T 13-09-2016 IPR000089 Biotin/lipoyl attachment THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 Pfam PF00364 Biotin-requiring enzyme 221 292 6.7E-22 T 13-09-2016 IPR000089 Biotin/lipoyl attachment THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 Pfam PF00364 Biotin-requiring enzyme 5 74 1.2E-21 T 13-09-2016 IPR000089 Biotin/lipoyl attachment THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 PANTHER PTHR23151:SF68 342 386 5.0E-236 T 13-09-2016 THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 PANTHER PTHR23151:SF68 21 218 5.0E-236 T 13-09-2016 THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 SUPERFAMILY SSF51230 109 201 1.13E-19 T 13-09-2016 IPR011053 Single hybrid motif THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 25 54 - T 13-09-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 419 648 2.2E-76 T 13-09-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 199 648 1.5E-204 T 13-09-2016 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 SUPERFAMILY SSF51230 218 304 2.62E-20 T 13-09-2016 IPR011053 Single hybrid motif THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 Pfam PF02817 e3 binding domain 345 380 2.3E-14 T 13-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 133 162 - T 13-09-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 Gene3D G3DSA:2.40.50.100 221 296 4.2E-21 T 13-09-2016 THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 Gene3D G3DSA:2.40.50.100 5 78 1.3E-23 T 13-09-2016 THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 Gene3D G3DSA:2.40.50.100 111 184 1.6E-20 T 13-09-2016 THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 SUPERFAMILY SSF47005 338 384 1.44E-12 T 13-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 SUPERFAMILY SSF51230 5 93 3.27E-22 T 13-09-2016 IPR011053 Single hybrid motif THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 243 272 - T 13-09-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 PANTHER PTHR23151 402 648 5.0E-236 T 13-09-2016 THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 Gene3D G3DSA:3.30.559.10 409 648 1.0E-81 T 13-09-2016 IPR023213 Chloramphenicol acetyltransferase-like domain THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 PANTHER PTHR23151 342 386 5.0E-236 T 13-09-2016 THL1_RS26195 473e683edcb0555dcf9341220f47a9fc 648 PANTHER PTHR23151 21 218 5.0E-236 T 13-09-2016 THL1_RS22975 5c551807af9eca9d89ed241818f17c04 474 Gene3D G3DSA:3.40.605.10 2 259 4.2E-96 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS22975 5c551807af9eca9d89ed241818f17c04 474 Pfam PF00171 Aldehyde dehydrogenase family 19 470 3.3E-164 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS22975 5c551807af9eca9d89ed241818f17c04 474 PANTHER PTHR11699 1 474 1.1E-290 T 13-09-2016 THL1_RS22975 5c551807af9eca9d89ed241818f17c04 474 SUPERFAMILY SSF53720 2 473 4.71E-158 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS22975 5c551807af9eca9d89ed241818f17c04 474 PANTHER PTHR11699:SF109 1 474 1.1E-290 T 13-09-2016 IPR015657 Aminobutyraldehyde dehydrogenase KEGG: 00330+1.2.1.19|KEGG: 00410+1.2.1.19|MetaCyc: PWY-2|MetaCyc: PWY-3|UniPathway: UPA00188 THL1_RS22975 5c551807af9eca9d89ed241818f17c04 474 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 245 252 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS22975 5c551807af9eca9d89ed241818f17c04 474 Gene3D G3DSA:3.40.309.10 260 450 8.1E-62 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS11080 9b524b19335591a5870f10b326e0bac1 208 SUPERFAMILY SSF47616 75 199 9.01E-26 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS11080 9b524b19335591a5870f10b326e0bac1 208 SUPERFAMILY SSF52833 4 85 3.99E-23 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS11080 9b524b19335591a5870f10b326e0bac1 208 Gene3D G3DSA:1.20.1050.10 89 199 4.6E-27 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS11080 9b524b19335591a5870f10b326e0bac1 208 PANTHER PTHR11260 1 195 1.1E-44 T 13-09-2016 THL1_RS11080 9b524b19335591a5870f10b326e0bac1 208 Gene3D G3DSA:3.40.30.10 5 88 1.3E-25 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS11080 9b524b19335591a5870f10b326e0bac1 208 Pfam PF00043 Glutathione S-transferase, C-terminal domain 126 193 3.6E-10 T 13-09-2016 IPR004046 Glutathione S-transferase, C-terminal THL1_RS11080 9b524b19335591a5870f10b326e0bac1 208 Pfam PF02798 Glutathione S-transferase, N-terminal domain 5 77 2.7E-14 T 13-09-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THL1_RS09655 8c0f2a2bc7b3add17a194564bbb4c655 382 Gene3D G3DSA:1.20.140.10 220 380 1.8E-60 T 13-09-2016 THL1_RS09655 8c0f2a2bc7b3add17a194564bbb4c655 382 PANTHER PTHR10909 7 381 6.2E-263 T 13-09-2016 THL1_RS09655 8c0f2a2bc7b3add17a194564bbb4c655 382 Gene3D G3DSA:2.40.110.10 126 219 3.3E-38 T 13-09-2016 THL1_RS09655 8c0f2a2bc7b3add17a194564bbb4c655 382 SUPERFAMILY SSF47203 231 380 8.05E-47 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS09655 8c0f2a2bc7b3add17a194564bbb4c655 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 380 4.7E-45 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS09655 8c0f2a2bc7b3add17a194564bbb4c655 382 SUPERFAMILY SSF56645 5 244 2.62E-72 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS09655 8c0f2a2bc7b3add17a194564bbb4c655 382 PANTHER PTHR10909:SF204 7 381 6.2E-263 T 13-09-2016 THL1_RS09655 8c0f2a2bc7b3add17a194564bbb4c655 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 339 358 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS09655 8c0f2a2bc7b3add17a194564bbb4c655 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 122 5.3E-27 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS09655 8c0f2a2bc7b3add17a194564bbb4c655 382 Gene3D G3DSA:1.10.540.10 4 124 8.2E-33 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS09655 8c0f2a2bc7b3add17a194564bbb4c655 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 220 5.0E-23 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS17775 e432aab3d57ec2456c8d4f324f5e2acb 552 Gene3D G3DSA:3.30.413.10 120 277 6.9E-41 T 13-09-2016 THL1_RS17775 e432aab3d57ec2456c8d4f324f5e2acb 552 SUPERFAMILY SSF55124 315 421 1.16E-23 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS17775 e432aab3d57ec2456c8d4f324f5e2acb 552 SUPERFAMILY SSF55124 252 276 1.16E-23 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS17775 e432aab3d57ec2456c8d4f324f5e2acb 552 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 53 109 3.5E-15 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS17775 e432aab3d57ec2456c8d4f324f5e2acb 552 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 329 398 4.3E-14 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS17775 e432aab3d57ec2456c8d4f324f5e2acb 552 PANTHER PTHR11493 327 551 6.5E-172 T 13-09-2016 THL1_RS17775 e432aab3d57ec2456c8d4f324f5e2acb 552 PANTHER PTHR11493 1 294 6.5E-172 T 13-09-2016 THL1_RS17775 e432aab3d57ec2456c8d4f324f5e2acb 552 Gene3D G3DSA:3.90.480.10 321 403 7.8E-37 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS17775 e432aab3d57ec2456c8d4f324f5e2acb 552 Gene3D G3DSA:3.90.480.10 48 117 7.8E-37 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS17775 e432aab3d57ec2456c8d4f324f5e2acb 552 SUPERFAMILY SSF56014 120 285 5.5E-47 T 13-09-2016 THL1_RS17775 e432aab3d57ec2456c8d4f324f5e2acb 552 Gene3D G3DSA:3.30.413.10 408 548 2.6E-37 T 13-09-2016 THL1_RS17775 e432aab3d57ec2456c8d4f324f5e2acb 552 SUPERFAMILY SSF55124 1 125 2.62E-29 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS17775 e432aab3d57ec2456c8d4f324f5e2acb 552 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 412 547 5.3E-13 T 13-09-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS17775 e432aab3d57ec2456c8d4f324f5e2acb 552 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 119 273 4.0E-41 T 13-09-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS17775 e432aab3d57ec2456c8d4f324f5e2acb 552 SUPERFAMILY SSF56014 407 548 1.83E-40 T 13-09-2016 THL1_RS17775 e432aab3d57ec2456c8d4f324f5e2acb 552 PANTHER PTHR11493:SF47 327 551 6.5E-172 T 13-09-2016 THL1_RS17775 e432aab3d57ec2456c8d4f324f5e2acb 552 PANTHER PTHR11493:SF47 1 294 6.5E-172 T 13-09-2016 THL1_RS12295 b8960076929d031bda53a536ec9b9526 225 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 28 182 42.636 T 13-09-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 THL1_RS12295 b8960076929d031bda53a536ec9b9526 225 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 149 165 - T 13-09-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 THL1_RS12295 b8960076929d031bda53a536ec9b9526 225 PANTHER PTHR11995 2 221 3.4E-132 T 13-09-2016 THL1_RS12295 b8960076929d031bda53a536ec9b9526 225 PANTHER PTHR11995:SF14 2 221 3.4E-132 T 13-09-2016 THL1_RS12295 b8960076929d031bda53a536ec9b9526 225 SUPERFAMILY SSF56770 45 190 8.77E-64 T 13-09-2016 THL1_RS12295 b8960076929d031bda53a536ec9b9526 225 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 40 183 8.9E-68 T 13-09-2016 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 THL1_RS12295 b8960076929d031bda53a536ec9b9526 225 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 88 175 1.1E-21 T 13-09-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 THL1_RS12295 b8960076929d031bda53a536ec9b9526 225 Gene3D G3DSA:3.40.50.700 52 179 2.1E-30 T 13-09-2016 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 THL1_RS13420 8d99c8b2c5a5ea97174e36fc90f7eaf4 787 ProSitePatterns PS00116 DNA polymerase family B signature. 545 553 - T 13-09-2016 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS13420 8d99c8b2c5a5ea97174e36fc90f7eaf4 787 Pfam PF00136 DNA polymerase family B 379 739 1.7E-41 T 13-09-2016 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS13420 8d99c8b2c5a5ea97174e36fc90f7eaf4 787 Gene3D G3DSA:3.90.1600.10 399 433 2.1E-10 T 13-09-2016 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS13420 8d99c8b2c5a5ea97174e36fc90f7eaf4 787 Gene3D G3DSA:3.90.1600.10 514 584 2.1E-10 T 13-09-2016 IPR023211 DNA polymerase, palm domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS13420 8d99c8b2c5a5ea97174e36fc90f7eaf4 787 Gene3D G3DSA:3.30.420.10 150 366 1.1E-35 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS13420 8d99c8b2c5a5ea97174e36fc90f7eaf4 787 Pfam PF03104 DNA polymerase family B, exonuclease domain 73 298 2.8E-12 T 13-09-2016 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS13420 8d99c8b2c5a5ea97174e36fc90f7eaf4 787 SMART SM00486 150 557 2.1E-66 T 13-09-2016 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS13420 8d99c8b2c5a5ea97174e36fc90f7eaf4 787 SUPERFAMILY SSF56672 386 781 3.45E-113 T 13-09-2016 THL1_RS13420 8d99c8b2c5a5ea97174e36fc90f7eaf4 787 SUPERFAMILY SSF53098 4 391 3.85E-94 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS13420 8d99c8b2c5a5ea97174e36fc90f7eaf4 787 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 543 551 7.1E-10 T 13-09-2016 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS13420 8d99c8b2c5a5ea97174e36fc90f7eaf4 787 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 491 503 7.1E-10 T 13-09-2016 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS13420 8d99c8b2c5a5ea97174e36fc90f7eaf4 787 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 417 430 7.1E-10 T 13-09-2016 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS13420 8d99c8b2c5a5ea97174e36fc90f7eaf4 787 PANTHER PTHR10322 77 780 9.6E-202 T 13-09-2016 THL1_RS26980 f4a6940a9e594db210d43732b8307928 288 Gene3D G3DSA:3.40.50.720 1 230 1.9E-56 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS26980 f4a6940a9e594db210d43732b8307928 288 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 286 9.1E-103 T 13-09-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family THL1_RS26980 f4a6940a9e594db210d43732b8307928 288 Pfam PF04321 RmlD substrate binding domain 1 286 2.3E-108 T 13-09-2016 IPR029903 RmlD-like substrate binding domain THL1_RS26980 f4a6940a9e594db210d43732b8307928 288 PANTHER PTHR10491:SF4 1 286 1.8E-97 T 13-09-2016 THL1_RS26980 f4a6940a9e594db210d43732b8307928 288 PANTHER PTHR10491 1 286 1.8E-97 T 13-09-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family THL1_RS26980 f4a6940a9e594db210d43732b8307928 288 SUPERFAMILY SSF51735 1 286 1.16E-98 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 119 272 7.0E-37 T 13-09-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 415 552 3.4E-14 T 13-09-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 SUPERFAMILY SSF55124 315 422 1.31E-22 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 SUPERFAMILY SSF55124 252 276 1.31E-22 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 PANTHER PTHR11493 327 551 6.0E-166 T 13-09-2016 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 PANTHER PTHR11493 1 294 6.0E-166 T 13-09-2016 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 PRINTS PR00397 Sirohaem Fe-binding site signature 411 429 7.1E-5 T 13-09-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 PRINTS PR00397 Sirohaem Fe-binding site signature 457 475 7.1E-5 T 13-09-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 SUPERFAMILY SSF56014 408 553 1.44E-42 T 13-09-2016 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 Gene3D G3DSA:3.30.413.10 120 278 3.2E-39 T 13-09-2016 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 PANTHER PTHR11493:SF47 327 551 6.0E-166 T 13-09-2016 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 PANTHER PTHR11493:SF47 1 294 6.0E-166 T 13-09-2016 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 SUPERFAMILY SSF56014 120 287 3.79E-44 T 13-09-2016 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 49 111 7.8E-19 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 347 398 7.1E-13 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 Gene3D G3DSA:3.90.480.10 321 404 4.5E-36 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 Gene3D G3DSA:3.90.480.10 48 117 4.5E-36 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 SUPERFAMILY SSF55124 1 126 4.42E-32 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS04690 a57440ede267c3a3c86713f3bae3e3b4 556 Gene3D G3DSA:3.30.413.10 409 549 2.3E-40 T 13-09-2016 THL1_RS18465 939239941fef4db51479d308fc729cbc 309 PANTHER PTHR10909:SF294 104 305 3.8E-130 T 13-09-2016 THL1_RS18465 939239941fef4db51479d308fc729cbc 309 Pfam PF01012 Electron transfer flavoprotein domain 4 167 1.1E-38 T 13-09-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 THL1_RS18465 939239941fef4db51479d308fc729cbc 309 Gene3D G3DSA:3.40.50.620 1 182 9.1E-64 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS18465 939239941fef4db51479d308fc729cbc 309 SUPERFAMILY SSF52402 3 186 1.26E-56 T 13-09-2016 THL1_RS18465 939239941fef4db51479d308fc729cbc 309 PIRSF PIRSF000089 1 309 4.6E-106 T 13-09-2016 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 THL1_RS18465 939239941fef4db51479d308fc729cbc 309 PANTHER PTHR10909 104 305 3.8E-130 T 13-09-2016 THL1_RS18465 939239941fef4db51479d308fc729cbc 309 SMART SM00893 3 182 1.7E-54 T 13-09-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 THL1_RS18465 939239941fef4db51479d308fc729cbc 309 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 253 279 - T 13-09-2016 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site THL1_RS18465 939239941fef4db51479d308fc729cbc 309 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 190 272 1.0E-36 T 13-09-2016 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal THL1_RS18465 939239941fef4db51479d308fc729cbc 309 SUPERFAMILY SSF52467 187 309 8.18E-49 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS18465 939239941fef4db51479d308fc729cbc 309 Gene3D G3DSA:3.40.50.1220 184 307 6.9E-62 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS08305 1b379baeaf0f9bb22a82a8dfd1e4f06b 271 SUPERFAMILY SSF56317 1 251 5.36E-70 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS08305 1b379baeaf0f9bb22a82a8dfd1e4f06b 271 PANTHER PTHR23088 1 261 4.0E-73 T 13-09-2016 THL1_RS08305 1b379baeaf0f9bb22a82a8dfd1e4f06b 271 Gene3D G3DSA:3.60.110.10 1 252 4.3E-71 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS08305 1b379baeaf0f9bb22a82a8dfd1e4f06b 271 Pfam PF00795 Carbon-nitrogen hydrolase 5 242 2.2E-47 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS09930 0eb51b83b1472da1a83d2ff03feb3ad6 306 Pfam PF03466 LysR substrate binding domain 87 286 5.1E-44 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS09930 0eb51b83b1472da1a83d2ff03feb3ad6 306 Gene3D G3DSA:3.40.190.10 177 253 1.5E-17 T 13-09-2016 THL1_RS09930 0eb51b83b1472da1a83d2ff03feb3ad6 306 SUPERFAMILY SSF46785 1 87 3.31E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09930 0eb51b83b1472da1a83d2ff03feb3ad6 306 SUPERFAMILY SSF53850 87 286 1.74E-45 T 13-09-2016 THL1_RS09930 0eb51b83b1472da1a83d2ff03feb3ad6 306 PANTHER PTHR30537 1 304 7.1E-132 T 13-09-2016 THL1_RS09930 0eb51b83b1472da1a83d2ff03feb3ad6 306 Gene3D G3DSA:3.40.190.10 91 176 2.9E-22 T 13-09-2016 THL1_RS09930 0eb51b83b1472da1a83d2ff03feb3ad6 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.0E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS09930 0eb51b83b1472da1a83d2ff03feb3ad6 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.0E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS09930 0eb51b83b1472da1a83d2ff03feb3ad6 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.0E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS09930 0eb51b83b1472da1a83d2ff03feb3ad6 306 PANTHER PTHR30537:SF27 1 304 7.1E-132 T 13-09-2016 THL1_RS09930 0eb51b83b1472da1a83d2ff03feb3ad6 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 61 7.0E-19 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS09930 0eb51b83b1472da1a83d2ff03feb3ad6 306 Gene3D G3DSA:1.10.10.10 2 87 3.9E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS28030 12474837d5035e939d741fda5c42dc03 556 Gene3D G3DSA:1.10.3720.10 295 552 4.2E-51 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS28030 12474837d5035e939d741fda5c42dc03 556 PANTHER PTHR30425 196 554 1.7E-248 T 13-09-2016 THL1_RS28030 12474837d5035e939d741fda5c42dc03 556 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 288 548 8.1E-75 T 13-09-2016 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 THL1_RS28030 12474837d5035e939d741fda5c42dc03 556 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 324 550 5.7E-19 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS28030 12474837d5035e939d741fda5c42dc03 556 PANTHER PTHR30425:SF7 196 554 1.7E-248 T 13-09-2016 THL1_RS28030 12474837d5035e939d741fda5c42dc03 556 SUPERFAMILY SSF161098 286 538 1.26E-36 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS27590 abac26234a2df590201218d1c652e768 301 Gene3D G3DSA:3.20.20.70 6 291 3.0E-88 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS27590 abac26234a2df590201218d1c652e768 301 SUPERFAMILY SSF51569 1 289 1.81E-71 T 13-09-2016 THL1_RS27590 abac26234a2df590201218d1c652e768 301 ProSitePatterns PS01062 Hydroxymethylglutaryl-coenzyme A lyase active site. 233 242 - T 13-09-2016 IPR000138 Hydroxymethylglutaryl-CoA lyase, active site GO:0004419 KEGG: 00072+4.1.3.4|KEGG: 00280+4.1.3.4|KEGG: 00281+4.1.3.4|KEGG: 00650+4.1.3.4|MetaCyc: PWY-5074|UniPathway: UPA00896 THL1_RS27590 abac26234a2df590201218d1c652e768 301 PANTHER PTHR10277 2 297 3.5E-180 T 13-09-2016 THL1_RS27590 abac26234a2df590201218d1c652e768 301 PANTHER PTHR10277:SF40 2 297 3.5E-180 T 13-09-2016 THL1_RS27590 abac26234a2df590201218d1c652e768 301 Pfam PF00682 HMGL-like 7 278 1.8E-55 T 13-09-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 THL1_RS00650 080315b258973815a3dfa0c6f0e57239 189 Gene3D G3DSA:1.10.357.10 60 178 4.2E-31 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS00650 080315b258973815a3dfa0c6f0e57239 189 Gene3D G3DSA:1.10.10.60 6 59 1.0E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS00650 080315b258973815a3dfa0c6f0e57239 189 PANTHER PTHR30055 2 175 2.3E-21 T 13-09-2016 THL1_RS00650 080315b258973815a3dfa0c6f0e57239 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 61 6.3E-9 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS00650 080315b258973815a3dfa0c6f0e57239 189 PANTHER PTHR30055:SF59 2 175 2.3E-21 T 13-09-2016 THL1_RS00650 080315b258973815a3dfa0c6f0e57239 189 SUPERFAMILY SSF46689 3 68 1.44E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS00650 080315b258973815a3dfa0c6f0e57239 189 SUPERFAMILY SSF48498 82 180 4.45E-23 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS04700 2260bbd5240becf8ae67b801d7280b75 520 PANTHER PTHR22777 1 516 4.5E-261 T 13-09-2016 THL1_RS04700 2260bbd5240becf8ae67b801d7280b75 520 Pfam PF03741 Integral membrane protein TerC family 14 203 1.2E-47 T 13-09-2016 IPR005496 Integral membrane protein TerC GO:0016021 THL1_RS04700 2260bbd5240becf8ae67b801d7280b75 520 Pfam PF03471 Transporter associated domain 442 515 2.9E-16 T 13-09-2016 IPR005170 Transporter-associated domain THL1_RS04700 2260bbd5240becf8ae67b801d7280b75 520 Pfam PF00571 CBS domain 378 424 1.4E-6 T 13-09-2016 IPR000644 CBS domain THL1_RS04700 2260bbd5240becf8ae67b801d7280b75 520 SUPERFAMILY SSF54631 294 429 4.03E-20 T 13-09-2016 THL1_RS04700 2260bbd5240becf8ae67b801d7280b75 520 Gene3D G3DSA:3.10.580.10 292 417 8.4E-9 T 13-09-2016 THL1_RS04700 2260bbd5240becf8ae67b801d7280b75 520 Gene3D G3DSA:3.30.465.10 418 515 2.0E-20 T 13-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THL1_RS04700 2260bbd5240becf8ae67b801d7280b75 520 SUPERFAMILY SSF56176 442 517 8.72E-16 T 13-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THL1_RS04700 2260bbd5240becf8ae67b801d7280b75 520 SMART SM01091 438 517 8.9E-20 T 13-09-2016 IPR005170 Transporter-associated domain THL1_RS04700 2260bbd5240becf8ae67b801d7280b75 520 PANTHER PTHR22777:SF14 1 516 4.5E-261 T 13-09-2016 THL1_RS03485 802ddbc7325d0470fd015b0043af07b5 122 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 122 25.131 T 13-09-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03485 802ddbc7325d0470fd015b0043af07b5 122 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 4 48 1.1E-16 T 13-09-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03485 802ddbc7325d0470fd015b0043af07b5 122 SUPERFAMILY SSF48300 4 58 4.97E-15 T 13-09-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03485 802ddbc7325d0470fd015b0043af07b5 122 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 122 1.1E-46 T 13-09-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03485 802ddbc7325d0470fd015b0043af07b5 122 Gene3D G3DSA:3.30.1390.10 52 122 1.5E-32 T 13-09-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like THL1_RS03485 802ddbc7325d0470fd015b0043af07b5 122 SUPERFAMILY SSF54736 51 122 9.24E-25 T 13-09-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like THL1_RS03485 802ddbc7325d0470fd015b0043af07b5 122 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 58 95 2.0E-12 T 13-09-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 THL1_RS03485 802ddbc7325d0470fd015b0043af07b5 122 Gene3D G3DSA:1.20.5.710 2 51 2.7E-22 T 13-09-2016 THL1_RS03485 802ddbc7325d0470fd015b0043af07b5 122 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 56 122 1.1E-29 T 13-09-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 THL1_RS14760 da4d40076ad0543e83af46e49c971d02 236 PANTHER PTHR30450 1 236 2.7E-135 T 13-09-2016 THL1_RS14760 da4d40076ad0543e83af46e49c971d02 236 Gene3D G3DSA:1.10.3720.10 21 228 7.9E-34 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS14760 da4d40076ad0543e83af46e49c971d02 236 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 21 122 6.3E-16 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS14760 da4d40076ad0543e83af46e49c971d02 236 SUPERFAMILY SSF161098 18 220 7.19E-35 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS14760 da4d40076ad0543e83af46e49c971d02 236 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 227 8.1E-16 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS14760 da4d40076ad0543e83af46e49c971d02 236 PANTHER PTHR30450:SF5 1 236 2.7E-135 T 13-09-2016 THL1_RS13035 7765d30e97984d4d6245815e9f7f1ccb 445 PANTHER PTHR30341:SF0 286 444 1.8E-150 T 13-09-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 THL1_RS13035 7765d30e97984d4d6245815e9f7f1ccb 445 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 18 429 7.0E-123 T 13-09-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 THL1_RS13035 7765d30e97984d4d6245815e9f7f1ccb 445 PANTHER PTHR30341 286 444 1.8E-150 T 13-09-2016 THL1_RS13035 7765d30e97984d4d6245815e9f7f1ccb 445 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 15 439 22.332 T 13-09-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 THL1_RS13035 7765d30e97984d4d6245815e9f7f1ccb 445 Gene3D G3DSA:1.20.1530.10 297 430 3.8E-140 T 13-09-2016 IPR023171 Na/H antiporter domain THL1_RS13035 7765d30e97984d4d6245815e9f7f1ccb 445 Gene3D G3DSA:1.20.1530.10 14 254 3.8E-140 T 13-09-2016 IPR023171 Na/H antiporter domain THL1_RS13035 7765d30e97984d4d6245815e9f7f1ccb 445 PANTHER PTHR30341:SF0 1 253 1.8E-150 T 13-09-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 THL1_RS13035 7765d30e97984d4d6245815e9f7f1ccb 445 PANTHER PTHR30341 1 253 1.8E-150 T 13-09-2016 THL1_RS13035 7765d30e97984d4d6245815e9f7f1ccb 445 Pfam PF06965 Na+/H+ antiporter 1 17 428 1.6E-139 T 13-09-2016 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 THL1_RS26435 9536d2c31572933540a88fa0f6f3a2c6 133 SUPERFAMILY SSF141734 4 119 2.09E-48 T 13-09-2016 THL1_RS26435 9536d2c31572933540a88fa0f6f3a2c6 133 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 30 104 1.8E-33 T 13-09-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 THL1_RS26435 9536d2c31572933540a88fa0f6f3a2c6 133 PANTHER PTHR21256 1 119 5.9E-63 T 13-09-2016 THL1_RS26435 9536d2c31572933540a88fa0f6f3a2c6 133 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 4 108 32.814 T 13-09-2016 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 THL1_RS26435 9536d2c31572933540a88fa0f6f3a2c6 133 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 53 104 1.0E-23 T 13-09-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 SUPERFAMILY SSF55681 467 684 4.17E-52 T 13-09-2016 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 SUPERFAMILY SSF56037 195 395 1.39E-73 T 13-09-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 Gene3D G3DSA:3.30.70.380 700 791 8.8E-31 T 13-09-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 Pfam PF03147 Ferredoxin-fold anticodon binding domain 698 791 2.8E-29 T 13-09-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 PANTHER PTHR10947 2 791 0.0 T 13-09-2016 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 Pfam PF03483 B3/4 domain 211 384 4.0E-69 T 13-09-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 Gene3D G3DSA:2.40.50.140 40 153 3.9E-44 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 Gene3D G3DSA:3.30.930.10 497 687 5.3E-64 T 13-09-2016 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 SUPERFAMILY SSF54991 693 791 1.83E-30 T 13-09-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 SUPERFAMILY SSF50249 35 193 2.45E-49 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 785 46.54 T 13-09-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 Pfam PF01588 Putative tRNA binding domain 45 144 3.7E-24 T 13-09-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 Pfam PF03484 tRNA synthetase B5 domain 405 471 1.6E-17 T 13-09-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 791 2.5E-259 T 13-09-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 SMART SM00874 402 471 2.2E-27 T 13-09-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 SMART SM00873 211 384 7.0E-94 T 13-09-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 Gene3D G3DSA:3.30.56.10 1 38 1.5E-24 T 13-09-2016 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 Gene3D G3DSA:3.30.56.10 154 183 1.5E-24 T 13-09-2016 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 PANTHER PTHR10947:SF0 2 791 0.0 T 13-09-2016 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 SMART SM00896 698 791 6.6E-45 T 13-09-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 Gene3D G3DSA:3.30.56.20 403 475 1.7E-23 T 13-09-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 Gene3D G3DSA:3.50.40.10 199 391 1.3E-80 T 13-09-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 THL1_RS17570 e33bf12d7b7d6ed83f96e2356c81e0e1 792 SUPERFAMILY SSF46955 403 475 3.39E-17 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS17185 456b78f3e8e6c3e8048eb7e8e83fcde5 519 SUPERFAMILY SSF56801 3 514 3.79E-142 T 13-09-2016 THL1_RS17185 456b78f3e8e6c3e8048eb7e8e83fcde5 519 Gene3D G3DSA:3.30.300.30 412 512 6.9E-33 T 13-09-2016 THL1_RS17185 456b78f3e8e6c3e8048eb7e8e83fcde5 519 PANTHER PTHR24096 3 512 6.8E-150 T 13-09-2016 THL1_RS17185 456b78f3e8e6c3e8048eb7e8e83fcde5 519 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS17185 456b78f3e8e6c3e8048eb7e8e83fcde5 519 Pfam PF00501 AMP-binding enzyme 13 417 2.9E-89 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS17185 456b78f3e8e6c3e8048eb7e8e83fcde5 519 Pfam PF13193 AMP-binding enzyme C-terminal domain 426 501 3.9E-20 T 13-09-2016 IPR025110 AMP-binding enzyme C-terminal domain THL1_RS17185 456b78f3e8e6c3e8048eb7e8e83fcde5 519 Gene3D G3DSA:2.30.38.10 336 408 8.3E-27 T 13-09-2016 THL1_RS17185 456b78f3e8e6c3e8048eb7e8e83fcde5 519 Gene3D G3DSA:3.40.50.980 3 166 1.1E-25 T 13-09-2016 THL1_RS17185 456b78f3e8e6c3e8048eb7e8e83fcde5 519 Gene3D G3DSA:3.40.50.980 167 321 2.6E-35 T 13-09-2016 THL1_RS19615 5d7267d2682c4797af15e9886588b9ca 110 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 22 109 3.2E-25 T 13-09-2016 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 THL1_RS19615 5d7267d2682c4797af15e9886588b9ca 110 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 3 110 17.887 T 13-09-2016 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 THL1_RS19615 5d7267d2682c4797af15e9886588b9ca 110 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 74 90 4.6E-17 T 13-09-2016 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 THL1_RS19615 5d7267d2682c4797af15e9886588b9ca 110 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 95 108 4.6E-17 T 13-09-2016 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 THL1_RS19615 5d7267d2682c4797af15e9886588b9ca 110 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 39 55 4.6E-17 T 13-09-2016 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 THL1_RS19615 5d7267d2682c4797af15e9886588b9ca 110 Pfam PF02049 Flagellar hook-basal body complex protein FliE 23 110 8.7E-32 T 13-09-2016 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 THL1_RS19615 5d7267d2682c4797af15e9886588b9ca 110 PANTHER PTHR34653 11 110 7.1E-23 T 13-09-2016 THL1_RS16865 85affc7a71e4398e0c204350c9ff223b 77 Pfam PF13020 Domain of unknown function (DUF3883) 16 52 1.5E-6 T 13-09-2016 IPR024975 Domain of unknown function DUF3883 THL1_RS21410 9e78f640bf276c06101e803941c410c6 280 Pfam PF08668 HDOD domain 23 205 3.4E-23 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS21410 9e78f640bf276c06101e803941c410c6 280 Gene3D G3DSA:1.10.3150.10 14 261 1.1E-33 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS21410 9e78f640bf276c06101e803941c410c6 280 SUPERFAMILY SSF109604 13 250 3.77E-31 T 13-09-2016 THL1_RS19720 36f70c34df216be61cc830293f4e74cc 135 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 15 35 - T 13-09-2016 IPR019776 Flagellar basal body rod protein, conserved site THL1_RS19720 36f70c34df216be61cc830293f4e74cc 135 Pfam PF00460 Flagella basal body rod protein 11 39 8.6E-9 T 13-09-2016 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 THL1_RS19720 36f70c34df216be61cc830293f4e74cc 135 PIRSF PIRSF002889 1 135 1.3E-45 T 13-09-2016 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 THL1_RS19720 36f70c34df216be61cc830293f4e74cc 135 PANTHER PTHR30435:SF12 2 135 1.1E-43 T 13-09-2016 THL1_RS19720 36f70c34df216be61cc830293f4e74cc 135 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 5 132 1.2E-42 T 13-09-2016 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 THL1_RS19720 36f70c34df216be61cc830293f4e74cc 135 PANTHER PTHR30435 2 135 1.1E-43 T 13-09-2016 THL1_RS13515 e00e113939add77ddf026276c769f7bc 573 SUPERFAMILY SSF74863 28 136 1.96E-31 T 13-09-2016 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain THL1_RS13515 e00e113939add77ddf026276c769f7bc 573 SUPERFAMILY SSF52833 466 565 5.62E-22 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS13515 e00e113939add77ddf026276c769f7bc 573 Gene3D G3DSA:3.40.30.10 463 571 3.3E-27 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS13515 e00e113939add77ddf026276c769f7bc 573 PANTHER PTHR32234 1 572 5.9E-175 T 13-09-2016 THL1_RS13515 e00e113939add77ddf026276c769f7bc 573 Pfam PF11412 Disulphide bond corrector protein DsbC 28 134 9.7E-29 T 13-09-2016 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain THL1_RS13515 e00e113939add77ddf026276c769f7bc 573 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 171 365 6.7E-15 T 13-09-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 THL1_RS13515 e00e113939add77ddf026276c769f7bc 573 ProSitePatterns PS00194 Thioredoxin family active site. 478 496 - T 13-09-2016 IPR017937 Thioredoxin, conserved site GO:0045454 THL1_RS13515 e00e113939add77ddf026276c769f7bc 573 Gene3D G3DSA:2.60.40.1250 26 138 2.1E-35 T 13-09-2016 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain THL1_RS13515 e00e113939add77ddf026276c769f7bc 573 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 1 570 35.938 T 13-09-2016 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 THL1_RS13515 e00e113939add77ddf026276c769f7bc 573 PANTHER PTHR32234:SF0 1 572 5.9E-175 T 13-09-2016 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 THL1_RS13515 e00e113939add77ddf026276c769f7bc 573 Pfam PF13899 Thioredoxin-like 462 541 4.7E-14 T 13-09-2016 THL1_RS04375 df64fcdc1d1895d3893b003d1b92e557 348 PANTHER PTHR15032:SF4 6 343 6.8E-113 T 13-09-2016 THL1_RS04375 df64fcdc1d1895d3893b003d1b92e557 348 Gene3D G3DSA:3.60.15.10 54 339 3.8E-75 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS04375 df64fcdc1d1895d3893b003d1b92e557 348 Pfam PF12706 Beta-lactamase superfamily domain 103 301 1.1E-40 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS04375 df64fcdc1d1895d3893b003d1b92e557 348 SUPERFAMILY SSF56281 86 306 2.03E-34 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS04375 df64fcdc1d1895d3893b003d1b92e557 348 PANTHER PTHR15032 6 343 6.8E-113 T 13-09-2016 THL1_RS26820 18b17a10f86199a0a3eaad00708577e0 183 SUPERFAMILY SSF111126 1 180 4.71E-46 T 13-09-2016 IPR024096 NO signalling/Golgi transport ligand-binding domain THL1_RS26820 18b17a10f86199a0a3eaad00708577e0 183 Gene3D G3DSA:3.90.1520.10 1 180 9.5E-48 T 13-09-2016 THL1_RS26820 18b17a10f86199a0a3eaad00708577e0 183 SMART SM00989 118 177 0.0032 T 13-09-2016 IPR004096 4-vinyl reductase, 4VR THL1_RS26820 18b17a10f86199a0a3eaad00708577e0 183 Pfam PF07700 Haem-NO-binding 2 160 2.7E-38 T 13-09-2016 IPR011644 Heme-NO binding GO:0020037 KEGG: 00230+4.6.1.2 THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 Gene3D G3DSA:1.10.1780.10 1 147 2.3E-42 T 13-09-2016 IPR004176 Clp, N-terminal GO:0019538 THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 PANTHER PTHR11638 1 854 0.0 T 13-09-2016 THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 631 649 - T 13-09-2016 IPR028299 ClpA/B, conserved site 2 THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 13-09-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 SMART SM00382 198 343 2.7E-12 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 SMART SM00382 597 753 1.2E-10 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 SUPERFAMILY SSF52540 159 545 3.84E-99 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 SMART SM01086 764 853 2.9E-38 T 13-09-2016 IPR019489 Clp ATPase, C-terminal THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 Gene3D G3DSA:3.40.50.300 550 775 3.2E-57 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 Pfam PF07724 AAA domain (Cdc48 subfamily) 596 758 4.8E-55 T 13-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 Gene3D G3DSA:3.40.50.300 160 342 1.6E-49 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 320 1.5E-12 T 13-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 Gene3D G3DSA:1.10.8.60 776 854 1.7E-30 T 13-09-2016 THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 646 664 2.4E-42 T 13-09-2016 IPR001270 ClpA/B family GO:0005524 THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 675 693 2.4E-42 T 13-09-2016 IPR001270 ClpA/B family GO:0005524 THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 708 722 2.4E-42 T 13-09-2016 IPR001270 ClpA/B family GO:0005524 THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 601 619 2.4E-42 T 13-09-2016 IPR001270 ClpA/B family GO:0005524 THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 64 2.0E-11 T 13-09-2016 IPR004176 Clp, N-terminal GO:0019538 THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 2.2E-9 T 13-09-2016 IPR004176 Clp, N-terminal GO:0019538 THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 853 0.0 T 13-09-2016 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 SUPERFAMILY SSF81923 4 155 6.15E-39 T 13-09-2016 IPR004176 Clp, N-terminal GO:0019538 THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 764 843 2.0E-26 T 13-09-2016 IPR019489 Clp ATPase, C-terminal THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 PANTHER PTHR11638:SF18 1 854 0.0 T 13-09-2016 THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 SUPERFAMILY SSF52540 546 846 3.38E-82 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04995 f828411db690764b7ea535d77211f3f7 854 Gene3D G3DSA:1.10.8.60 344 428 4.3E-36 T 13-09-2016 THL1_RS28145 1ba905ed36744381fcecc6e2c24d85d7 488 Gene3D G3DSA:3.40.640.10 158 372 7.2E-64 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS28145 1ba905ed36744381fcecc6e2c24d85d7 488 Gene3D G3DSA:1.10.10.10 19 89 1.7E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS28145 1ba905ed36744381fcecc6e2c24d85d7 488 Pfam PF00155 Aminotransferase class I and II 153 396 5.0E-21 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS28145 1ba905ed36744381fcecc6e2c24d85d7 488 PANTHER PTHR11751:SF353 127 486 1.2E-124 T 13-09-2016 THL1_RS28145 1ba905ed36744381fcecc6e2c24d85d7 488 SMART SM00345 26 85 2.8E-17 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS28145 1ba905ed36744381fcecc6e2c24d85d7 488 SUPERFAMILY SSF53383 124 486 1.25E-87 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS28145 1ba905ed36744381fcecc6e2c24d85d7 488 SUPERFAMILY SSF46785 17 89 2.77E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS28145 1ba905ed36744381fcecc6e2c24d85d7 488 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 2.2E-7 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS28145 1ba905ed36744381fcecc6e2c24d85d7 488 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 2.2E-7 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS28145 1ba905ed36744381fcecc6e2c24d85d7 488 PANTHER PTHR11751 127 486 1.2E-124 T 13-09-2016 THL1_RS28145 1ba905ed36744381fcecc6e2c24d85d7 488 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 85 1.5E-16 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS00865 90302fe7c90e8babb762e720fb4be3d4 112 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 6 112 4.1E-15 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00865 90302fe7c90e8babb762e720fb4be3d4 112 SUPERFAMILY SSF161098 1 111 5.36E-21 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00865 90302fe7c90e8babb762e720fb4be3d4 112 PANTHER PTHR30151 1 112 4.0E-56 T 13-09-2016 THL1_RS00865 90302fe7c90e8babb762e720fb4be3d4 112 PANTHER PTHR30151:SF12 1 112 4.0E-56 T 13-09-2016 THL1_RS00865 90302fe7c90e8babb762e720fb4be3d4 112 Gene3D G3DSA:1.10.3720.10 1 111 8.2E-15 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS12020 67627db9a22ae71a3e616f617b98b171 464 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 10 459 3.8E-99 T 13-09-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 THL1_RS12020 67627db9a22ae71a3e616f617b98b171 464 SUPERFAMILY SSF56954 1 462 2.62E-104 T 13-09-2016 THL1_RS12020 67627db9a22ae71a3e616f617b98b171 464 Gene3D G3DSA:2.20.200.10 309 342 1.2E-12 T 13-09-2016 THL1_RS12020 67627db9a22ae71a3e616f617b98b171 464 Gene3D G3DSA:2.20.200.10 97 135 1.2E-12 T 13-09-2016 THL1_RS12020 67627db9a22ae71a3e616f617b98b171 464 PANTHER PTHR30203:SF13 9 464 8.6E-191 T 13-09-2016 THL1_RS12020 67627db9a22ae71a3e616f617b98b171 464 Pfam PF02321 Outer membrane efflux protein 277 457 1.4E-18 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS12020 67627db9a22ae71a3e616f617b98b171 464 Pfam PF02321 Outer membrane efflux protein 60 248 1.2E-23 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS12020 67627db9a22ae71a3e616f617b98b171 464 PANTHER PTHR30203 9 464 8.6E-191 T 13-09-2016 THL1_RS12020 67627db9a22ae71a3e616f617b98b171 464 Gene3D G3DSA:1.20.1600.10 51 86 2.0E-93 T 13-09-2016 THL1_RS12020 67627db9a22ae71a3e616f617b98b171 464 Gene3D G3DSA:1.20.1600.10 136 308 2.0E-93 T 13-09-2016 THL1_RS12020 67627db9a22ae71a3e616f617b98b171 464 Gene3D G3DSA:1.20.1600.10 346 460 2.0E-93 T 13-09-2016 THL1_RS08970 238743af3a783f6e8fcfceee307442d8 274 PANTHER PTHR11807 6 273 1.1E-117 T 13-09-2016 THL1_RS08970 238743af3a783f6e8fcfceee307442d8 274 PANTHER PTHR11807:SF16 6 273 1.1E-117 T 13-09-2016 THL1_RS08970 238743af3a783f6e8fcfceee307442d8 274 Pfam PF01171 PP-loop family 34 194 2.0E-13 T 13-09-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal THL1_RS08970 238743af3a783f6e8fcfceee307442d8 274 Gene3D G3DSA:3.40.50.620 20 195 5.4E-21 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS08970 238743af3a783f6e8fcfceee307442d8 274 PIRSF PIRSF004976 3 269 4.8E-71 T 13-09-2016 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 THL1_RS08970 238743af3a783f6e8fcfceee307442d8 274 Hamap MF_01850 tRNA 2-thiocytidine biosynthesis protein TtcA [ttcA]. 1 264 57.872 T 13-09-2016 IPR012089 2-thiocytidine tRNA biosynthesis protein, TtcA GO:0008033 THL1_RS08970 238743af3a783f6e8fcfceee307442d8 274 SUPERFAMILY SSF52402 10 228 1.26E-55 T 13-09-2016 THL1_RS18845 2cc089cf4bb260a17eec5f33367413f8 324 Gene3D G3DSA:1.10.760.10 229 316 3.8E-25 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18845 2cc089cf4bb260a17eec5f33367413f8 324 PANTHER PTHR33751:SF1 25 79 1.6E-120 T 13-09-2016 THL1_RS18845 2cc089cf4bb260a17eec5f33367413f8 324 PANTHER PTHR33751:SF1 109 320 1.6E-120 T 13-09-2016 THL1_RS18845 2cc089cf4bb260a17eec5f33367413f8 324 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 233 310 2.6E-12 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18845 2cc089cf4bb260a17eec5f33367413f8 324 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 144 217 4.5E-12 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18845 2cc089cf4bb260a17eec5f33367413f8 324 PANTHER PTHR33751 109 320 1.6E-120 T 13-09-2016 THL1_RS18845 2cc089cf4bb260a17eec5f33367413f8 324 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 33 316 6.1E-77 T 13-09-2016 IPR004678 Cytochrome c oxidase cbb3-type, subunit III UniPathway: UPA00705 THL1_RS18845 2cc089cf4bb260a17eec5f33367413f8 324 SUPERFAMILY SSF46626 55 78 4.73E-30 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18845 2cc089cf4bb260a17eec5f33367413f8 324 SUPERFAMILY SSF46626 123 218 4.73E-30 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18845 2cc089cf4bb260a17eec5f33367413f8 324 Gene3D G3DSA:1.10.760.10 138 219 9.3E-29 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18845 2cc089cf4bb260a17eec5f33367413f8 324 Gene3D G3DSA:1.10.760.10 60 82 9.3E-29 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18845 2cc089cf4bb260a17eec5f33367413f8 324 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 37 83 4.1E-22 T 13-09-2016 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal UniPathway: UPA00705 THL1_RS18845 2cc089cf4bb260a17eec5f33367413f8 324 PANTHER PTHR33751 25 79 1.6E-120 T 13-09-2016 THL1_RS18845 2cc089cf4bb260a17eec5f33367413f8 324 SUPERFAMILY SSF46626 228 318 3.58E-22 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18845 2cc089cf4bb260a17eec5f33367413f8 324 PIRSF PIRSF000006 1 317 5.9E-101 T 13-09-2016 IPR004678 Cytochrome c oxidase cbb3-type, subunit III UniPathway: UPA00705 THL1_RS15855 7eca29782912495e3975710063dfe6e4 429 Gene3D G3DSA:3.30.9.10 175 293 1.5E-8 T 13-09-2016 THL1_RS15855 7eca29782912495e3975710063dfe6e4 429 SUPERFAMILY SSF51905 3 154 1.96E-28 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS15855 7eca29782912495e3975710063dfe6e4 429 SUPERFAMILY SSF51905 247 337 1.96E-28 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS15855 7eca29782912495e3975710063dfe6e4 429 Pfam PF04820 Tryptophan halogenase 62 355 1.7E-9 T 13-09-2016 IPR006905 Tryptophan halogenase THL1_RS15855 7eca29782912495e3975710063dfe6e4 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 131 146 4.9E-8 T 13-09-2016 THL1_RS15855 7eca29782912495e3975710063dfe6e4 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 251 266 4.9E-8 T 13-09-2016 THL1_RS15855 7eca29782912495e3975710063dfe6e4 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 4.9E-8 T 13-09-2016 THL1_RS15855 7eca29782912495e3975710063dfe6e4 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 266 282 4.9E-8 T 13-09-2016 THL1_RS15855 7eca29782912495e3975710063dfe6e4 429 Gene3D G3DSA:3.50.50.60 3 47 6.0E-11 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS15855 7eca29782912495e3975710063dfe6e4 429 Gene3D G3DSA:3.50.50.60 82 144 6.0E-11 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS02825 369de373eb6d4cc6657c5b97bf3acffa 425 Gene3D G3DSA:3.90.1150.10 304 425 3.3E-38 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS02825 369de373eb6d4cc6657c5b97bf3acffa 425 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 9 419 6.6E-162 T 13-09-2016 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 THL1_RS02825 369de373eb6d4cc6657c5b97bf3acffa 425 Pfam PF00202 Aminotransferase class-III 17 420 1.7E-132 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS02825 369de373eb6d4cc6657c5b97bf3acffa 425 PANTHER PTHR11986 1 424 1.2E-284 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS02825 369de373eb6d4cc6657c5b97bf3acffa 425 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 273 - T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS02825 369de373eb6d4cc6657c5b97bf3acffa 425 PANTHER PTHR11986:SF70 1 424 1.2E-284 T 13-09-2016 THL1_RS02825 369de373eb6d4cc6657c5b97bf3acffa 425 Gene3D G3DSA:3.40.640.10 59 303 4.5E-85 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS02825 369de373eb6d4cc6657c5b97bf3acffa 425 SUPERFAMILY SSF53383 21 424 1.71E-132 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS15515 13b5de55602d3effbc2910c5a1c9e495 321 Pfam PF14870 Photosynthesis system II assembly factor YCF48 116 277 1.1E-10 T 13-09-2016 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain THL1_RS15515 13b5de55602d3effbc2910c5a1c9e495 321 Gene3D G3DSA:2.130.10.140 48 268 4.4E-31 T 13-09-2016 THL1_RS15515 13b5de55602d3effbc2910c5a1c9e495 321 SUPERFAMILY SSF110296 43 281 1.7E-41 T 13-09-2016 THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 Gene3D G3DSA:3.30.450.20 10 80 5.8E-9 T 13-09-2016 THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 SMART SM00387 308 416 7.0E-32 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 SUPERFAMILY SSF47384 236 267 1.08E-5 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 SUPERFAMILY SSF47384 161 208 1.08E-5 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 PANTHER PTHR24423 232 419 1.4E-92 T 13-09-2016 THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 SUPERFAMILY SSF55874 259 418 1.03E-44 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 PANTHER PTHR24423 10 144 1.4E-92 T 13-09-2016 THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 Gene3D G3DSA:1.10.287.130 235 254 3.0E-4 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 Gene3D G3DSA:1.10.287.130 169 199 3.0E-4 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 311 414 9.6E-22 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 Gene3D G3DSA:3.30.565.10 255 417 9.6E-43 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 PANTHER PTHR24423:SF497 168 201 1.4E-92 T 13-09-2016 THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 PANTHER PTHR24423:SF497 10 144 1.4E-92 T 13-09-2016 THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 Pfam PF00512 His Kinase A (phospho-acceptor) domain 175 267 1.2E-7 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 359 2.8E-19 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 413 2.8E-19 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 373 2.8E-19 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 394 2.8E-19 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 PANTHER PTHR24423:SF497 232 419 1.4E-92 T 13-09-2016 THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 SUPERFAMILY SSF55785 8 83 4.01E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS18920 2a2bc03bd453ad55fa9458ce9820bcea 422 PANTHER PTHR24423 168 201 1.4E-92 T 13-09-2016 THL1_RS06535 49ce0c4f43c1ee613b351b032e4a1be2 292 Pfam PF00106 short chain dehydrogenase 8 210 1.6E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06535 49ce0c4f43c1ee613b351b032e4a1be2 292 Gene3D G3DSA:3.40.50.720 8 255 1.3E-40 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS06535 49ce0c4f43c1ee613b351b032e4a1be2 292 PANTHER PTHR24322:SF211 11 30 1.3E-40 T 13-09-2016 THL1_RS06535 49ce0c4f43c1ee613b351b032e4a1be2 292 PANTHER PTHR24322:SF211 54 203 1.3E-40 T 13-09-2016 THL1_RS06535 49ce0c4f43c1ee613b351b032e4a1be2 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.9E-16 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06535 49ce0c4f43c1ee613b351b032e4a1be2 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 2.9E-16 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06535 49ce0c4f43c1ee613b351b032e4a1be2 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 162 2.9E-16 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06535 49ce0c4f43c1ee613b351b032e4a1be2 292 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 2.9E-16 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06535 49ce0c4f43c1ee613b351b032e4a1be2 292 PANTHER PTHR24322 11 30 1.3E-40 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06535 49ce0c4f43c1ee613b351b032e4a1be2 292 PANTHER PTHR24322 54 203 1.3E-40 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06535 49ce0c4f43c1ee613b351b032e4a1be2 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 106 1.6E-5 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06535 49ce0c4f43c1ee613b351b032e4a1be2 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 160 1.6E-5 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06535 49ce0c4f43c1ee613b351b032e4a1be2 292 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 1.6E-5 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06535 49ce0c4f43c1ee613b351b032e4a1be2 292 SUPERFAMILY SSF51735 5 255 2.34E-39 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS21110 c0e8be328b961ec52d574e8645064805 155 SUPERFAMILY SSF54909 65 154 2.68E-23 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS21110 c0e8be328b961ec52d574e8645064805 155 PANTHER PTHR30154:SF17 1 155 3.4E-60 T 13-09-2016 THL1_RS21110 c0e8be328b961ec52d574e8645064805 155 SMART SM00344 8 114 1.3E-36 T 13-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 THL1_RS21110 c0e8be328b961ec52d574e8645064805 155 Gene3D G3DSA:1.10.10.10 8 57 2.5E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS21110 c0e8be328b961ec52d574e8645064805 155 Pfam PF01037 Lrp/AsnC ligand binding domain 71 145 1.4E-22 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS21110 c0e8be328b961ec52d574e8645064805 155 PANTHER PTHR30154 1 155 3.4E-60 T 13-09-2016 THL1_RS21110 c0e8be328b961ec52d574e8645064805 155 SUPERFAMILY SSF46785 5 87 1.89E-16 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS21110 c0e8be328b961ec52d574e8645064805 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 1.9E-9 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS21110 c0e8be328b961ec52d574e8645064805 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.9E-9 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS21110 c0e8be328b961ec52d574e8645064805 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.9E-9 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS21110 c0e8be328b961ec52d574e8645064805 155 Gene3D G3DSA:3.30.70.920 58 154 2.7E-31 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS21110 c0e8be328b961ec52d574e8645064805 155 Pfam PF13404 AsnC-type helix-turn-helix domain 6 46 2.1E-16 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 TIGRFAM TIGR00838 argH: argininosuccinate lyase 8 460 4.2E-156 T 13-09-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 Gene3D G3DSA:1.10.40.30 380 435 3.2E-23 T 13-09-2016 THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 PRINTS PR00149 Fumarate lyase superfamily signature 280 296 1.0E-22 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 PRINTS PR00149 Fumarate lyase superfamily signature 107 125 1.0E-22 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 PRINTS PR00149 Fumarate lyase superfamily signature 152 170 1.0E-22 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 PRINTS PR00149 Fumarate lyase superfamily signature 236 263 1.0E-22 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 Hamap MF_00006 Argininosuccinate lyase [argH]. 7 458 37.861 T 13-09-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 ProSitePatterns PS00163 Fumarate lyases signature. 280 289 - T 13-09-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 PANTHER PTHR11444 1 460 1.0E-170 T 13-09-2016 IPR000362 Fumarate lyase family THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 Pfam PF00206 Lyase 31 305 7.5E-59 T 13-09-2016 IPR022761 Fumarate lyase, N-terminal THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 PRINTS PR00145 Argininosuccinate lyase family signature 236 260 2.5E-49 T 13-09-2016 THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 PRINTS PR00145 Argininosuccinate lyase family signature 147 167 2.5E-49 T 13-09-2016 THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 PRINTS PR00145 Argininosuccinate lyase family signature 198 214 2.5E-49 T 13-09-2016 THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 PRINTS PR00145 Argininosuccinate lyase family signature 280 296 2.5E-49 T 13-09-2016 THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 PRINTS PR00145 Argininosuccinate lyase family signature 315 334 2.5E-49 T 13-09-2016 THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 PRINTS PR00145 Argininosuccinate lyase family signature 106 128 2.5E-49 T 13-09-2016 THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 Gene3D G3DSA:1.20.200.10 126 187 2.2E-77 T 13-09-2016 THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 Gene3D G3DSA:1.20.200.10 232 379 2.2E-77 T 13-09-2016 THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 Pfam PF14698 Argininosuccinate lyase C-terminal 368 436 2.0E-19 T 13-09-2016 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 SUPERFAMILY SSF48557 16 461 1.16E-121 T 13-09-2016 IPR008948 L-Aspartase-like GO:0003824 THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 PANTHER PTHR11444:SF3 1 460 1.0E-170 T 13-09-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 Gene3D G3DSA:1.10.275.10 197 231 1.3E-41 T 13-09-2016 IPR024083 Fumarase/histidase, N-terminal THL1_RS07410 37a1e80a9d8c7fd2be602b61645b3047 475 Gene3D G3DSA:1.10.275.10 33 125 1.3E-41 T 13-09-2016 IPR024083 Fumarase/histidase, N-terminal THL1_RS23640 ebc67b206f04f90344bff0953f1e7296 394 PANTHER PTHR12526:SF363 5 380 4.2E-106 T 13-09-2016 THL1_RS23640 ebc67b206f04f90344bff0953f1e7296 394 Pfam PF13439 Glycosyltransferase Family 4 19 183 8.5E-24 T 13-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain THL1_RS23640 ebc67b206f04f90344bff0953f1e7296 394 SUPERFAMILY SSF53756 11 375 3.77E-74 T 13-09-2016 THL1_RS23640 ebc67b206f04f90344bff0953f1e7296 394 Gene3D G3DSA:3.40.50.2000 183 356 5.2E-24 T 13-09-2016 THL1_RS23640 ebc67b206f04f90344bff0953f1e7296 394 Pfam PF00534 Glycosyl transferases group 1 195 356 1.3E-25 T 13-09-2016 IPR001296 Glycosyl transferase, family 1 THL1_RS23640 ebc67b206f04f90344bff0953f1e7296 394 PANTHER PTHR12526 5 380 4.2E-106 T 13-09-2016 THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 Pfam PF00563 EAL domain 478 711 4.8E-73 T 13-09-2016 IPR001633 EAL domain THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 199 296 6.2E-13 T 13-09-2016 IPR000014 PAS domain THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 Gene3D G3DSA:3.20.20.450 475 721 2.3E-93 T 13-09-2016 IPR001633 EAL domain THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 PANTHER PTHR33121:SF13 436 725 3.1E-82 T 13-09-2016 THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 SMART SM00065 13 155 2.2E-5 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 SUPERFAMILY SSF55785 192 293 9.13E-20 T 13-09-2016 IPR000014 PAS domain THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 PANTHER PTHR33121 436 725 3.1E-82 T 13-09-2016 THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 Pfam PF00990 Diguanylate cyclase, GGDEF domain 302 454 1.6E-33 T 13-09-2016 IPR000160 GGDEF domain THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 SUPERFAMILY SSF141868 477 722 1.83E-86 T 13-09-2016 IPR001633 EAL domain THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 SMART SM00052 471 716 8.5E-109 T 13-09-2016 IPR001633 EAL domain THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 Gene3D G3DSA:3.30.450.20 166 289 1.1E-23 T 13-09-2016 THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 Pfam PF13185 GAF domain 57 145 2.9E-9 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 Gene3D G3DSA:3.30.450.40 18 146 8.0E-11 T 13-09-2016 IPR029016 GAF domain-like THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 Gene3D G3DSA:3.30.70.270 303 461 4.8E-41 T 13-09-2016 THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 Pfam PF08447 PAS fold 200 284 2.5E-18 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 299 458 2.8E-26 T 13-09-2016 IPR000160 GGDEF domain THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 SMART SM00267 291 461 1.3E-35 T 13-09-2016 IPR000160 GGDEF domain THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 SMART SM00091 173 243 0.0015 T 13-09-2016 IPR000014 PAS domain THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 SUPERFAMILY SSF55781 17 154 9.38E-17 T 13-09-2016 IPR029016 GAF domain-like THL1_RS17220 4eab2c69d949da289e1009acced637a3 725 SUPERFAMILY SSF55073 307 456 1.73E-36 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS25800 def71ea7675119cc5c7922b06a8391c4 135 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 2.7E-33 T 13-09-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS25800 def71ea7675119cc5c7922b06a8391c4 135 PANTHER PTHR21011:SF1 1 135 7.0E-37 T 13-09-2016 THL1_RS25800 def71ea7675119cc5c7922b06a8391c4 135 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.887 T 13-09-2016 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS25800 def71ea7675119cc5c7922b06a8391c4 135 Gene3D G3DSA:3.30.70.60 1 103 1.5E-39 T 13-09-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 THL1_RS25800 def71ea7675119cc5c7922b06a8391c4 135 ProSitePatterns PS01048 Ribosomal protein S6 signature. 43 52 - T 13-09-2016 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS25800 def71ea7675119cc5c7922b06a8391c4 135 SUPERFAMILY SSF54995 1 102 4.58E-36 T 13-09-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS25800 def71ea7675119cc5c7922b06a8391c4 135 PANTHER PTHR21011 1 135 7.0E-37 T 13-09-2016 THL1_RS25800 def71ea7675119cc5c7922b06a8391c4 135 Pfam PF01250 Ribosomal protein S6 3 91 4.1E-26 T 13-09-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 THL1_RS05945 ae11db5628bcacc7f1fea741647cae0a 173 SUPERFAMILY SSF47144 84 173 2.22E-22 T 13-09-2016 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 THL1_RS05945 ae11db5628bcacc7f1fea741647cae0a 173 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 4 172 22.132 T 13-09-2016 IPR004640 Co-chaperone Hsc20 GO:0006457|GO:0051087 THL1_RS05945 ae11db5628bcacc7f1fea741647cae0a 173 PANTHER PTHR14021:SF15 6 173 5.1E-44 T 13-09-2016 THL1_RS05945 ae11db5628bcacc7f1fea741647cae0a 173 Pfam PF07743 HSCB C-terminal oligomerisation domain 89 164 6.9E-16 T 13-09-2016 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 THL1_RS05945 ae11db5628bcacc7f1fea741647cae0a 173 PANTHER PTHR14021 6 173 5.1E-44 T 13-09-2016 IPR004640 Co-chaperone Hsc20 GO:0006457|GO:0051087 THL1_RS05945 ae11db5628bcacc7f1fea741647cae0a 173 Gene3D G3DSA:1.20.1280.20 86 173 5.2E-26 T 13-09-2016 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 THL1_RS05945 ae11db5628bcacc7f1fea741647cae0a 173 SUPERFAMILY SSF46565 6 77 1.31E-16 T 13-09-2016 IPR001623 DnaJ domain THL1_RS05945 ae11db5628bcacc7f1fea741647cae0a 173 SMART SM00271 4 69 6.3E-8 T 13-09-2016 IPR001623 DnaJ domain THL1_RS05945 ae11db5628bcacc7f1fea741647cae0a 173 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 16 171 4.3E-32 T 13-09-2016 IPR004640 Co-chaperone Hsc20 GO:0006457|GO:0051087 THL1_RS05945 ae11db5628bcacc7f1fea741647cae0a 173 Gene3D G3DSA:1.10.287.110 6 76 1.2E-21 T 13-09-2016 IPR001623 DnaJ domain THL1_RS01560 ba47e02ffd2c5d87a09b587ce503f4be 239 SUPERFAMILY SSF75217 74 239 1.66E-53 T 13-09-2016 IPR029028 Alpha/beta knot methyltransferases THL1_RS01560 ba47e02ffd2c5d87a09b587ce503f4be 239 PIRSF PIRSF015601 3 238 4.1E-61 T 13-09-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS01560 ba47e02ffd2c5d87a09b587ce503f4be 239 PANTHER PTHR30027 1 239 7.5E-89 T 13-09-2016 THL1_RS01560 ba47e02ffd2c5d87a09b587ce503f4be 239 PANTHER PTHR30027:SF3 1 239 7.5E-89 T 13-09-2016 THL1_RS01560 ba47e02ffd2c5d87a09b587ce503f4be 239 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 19 237 4.5E-63 T 13-09-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS01560 ba47e02ffd2c5d87a09b587ce503f4be 239 SUPERFAMILY SSF88697 3 68 3.73E-15 T 13-09-2016 IPR015947 PUA-like domain THL1_RS01560 ba47e02ffd2c5d87a09b587ce503f4be 239 Gene3D G3DSA:2.40.240.20 1 68 1.5E-23 T 13-09-2016 THL1_RS01560 ba47e02ffd2c5d87a09b587ce503f4be 239 Gene3D G3DSA:3.40.1280.10 74 238 1.9E-61 T 13-09-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THL1_RS01560 ba47e02ffd2c5d87a09b587ce503f4be 239 Pfam PF04452 RNA methyltransferase 19 233 1.6E-71 T 13-09-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS06750 57fd9c2fc4f8bd6692450eb067786941 352 PANTHER PTHR30006:SF10 1 352 2.6E-110 T 13-09-2016 THL1_RS06750 57fd9c2fc4f8bd6692450eb067786941 352 PANTHER PTHR30006 1 352 2.6E-110 T 13-09-2016 THL1_RS06750 57fd9c2fc4f8bd6692450eb067786941 352 Pfam PF13343 Bacterial extracellular solute-binding protein 87 334 2.2E-50 T 13-09-2016 THL1_RS06750 57fd9c2fc4f8bd6692450eb067786941 352 Gene3D G3DSA:3.40.190.10 139 274 4.8E-24 T 13-09-2016 THL1_RS06750 57fd9c2fc4f8bd6692450eb067786941 352 Gene3D G3DSA:3.40.190.10 275 322 1.7E-23 T 13-09-2016 THL1_RS06750 57fd9c2fc4f8bd6692450eb067786941 352 Gene3D G3DSA:3.40.190.10 1 134 1.7E-23 T 13-09-2016 THL1_RS06750 57fd9c2fc4f8bd6692450eb067786941 352 SUPERFAMILY SSF53850 44 345 4.78E-49 T 13-09-2016 THL1_RS05805 65ebe306c47a9320066a123a9069242a 406 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 281 379 6.3E-23 T 13-09-2016 IPR026843 Nuclease SbcCD subunit D, C-terminal domain THL1_RS05805 65ebe306c47a9320066a123a9069242a 406 PANTHER PTHR30337:SF0 1 387 3.6E-98 T 13-09-2016 THL1_RS05805 65ebe306c47a9320066a123a9069242a 406 SUPERFAMILY SSF56300 1 345 1.24E-55 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS05805 65ebe306c47a9320066a123a9069242a 406 PANTHER PTHR30337 1 387 3.6E-98 T 13-09-2016 THL1_RS05805 65ebe306c47a9320066a123a9069242a 406 Gene3D G3DSA:3.60.21.10 1 280 1.4E-64 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS05805 65ebe306c47a9320066a123a9069242a 406 Pfam PF00149 Calcineurin-like phosphoesterase 1 231 1.5E-12 T 13-09-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 THL1_RS05805 65ebe306c47a9320066a123a9069242a 406 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 259 2.9E-69 T 13-09-2016 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 THL1_RS11155 2dec3f4cd0871369441ac8eb702ae65d 263 Gene3D G3DSA:1.20.1290.10 48 124 3.7E-11 T 13-09-2016 IPR029032 AhpD-like THL1_RS11155 2dec3f4cd0871369441ac8eb702ae65d 263 Gene3D G3DSA:1.20.1290.10 157 236 1.9E-12 T 13-09-2016 IPR029032 AhpD-like THL1_RS11155 2dec3f4cd0871369441ac8eb702ae65d 263 Pfam PF02627 Carboxymuconolactone decarboxylase family 171 253 1.2E-11 T 13-09-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS11155 2dec3f4cd0871369441ac8eb702ae65d 263 SUPERFAMILY SSF69118 46 253 1.97E-42 T 13-09-2016 IPR029032 AhpD-like THL1_RS16080 4f1434c0afec64b3446208d5582d946a 323 Pfam PF04860 Phage portal protein 82 311 4.4E-14 T 13-09-2016 IPR006944 Bacteriophage/Gene transfer agent portal protein THL1_RS16080 4f1434c0afec64b3446208d5582d946a 323 TIGRFAM TIGR01540 portal_PBSX: phage portal protein, PBSX family 40 318 2.8E-75 T 13-09-2016 IPR006430 Phage portal protein PBSX family THL1_RS16080 4f1434c0afec64b3446208d5582d946a 323 PIRSF PIRSF018494 1 323 3.2E-150 T 13-09-2016 IPR030935 Phage portal protein PBSX family, Proteobacteria THL1_RS14195 2bbd97333fb8b1ad1141ddd1333e509b 398 SUPERFAMILY SSF53822 50 358 2.56E-24 T 13-09-2016 IPR028082 Periplasmic binding protein-like I THL1_RS14195 2bbd97333fb8b1ad1141ddd1333e509b 398 TIGRFAM TIGR03863 PQQ_ABC_bind: ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system 49 392 1.7E-155 T 13-09-2016 IPR022478 ABC transporter, substrate-binding protein, PQQ-dependent alcohol dehydrogenase system THL1_RS14195 2bbd97333fb8b1ad1141ddd1333e509b 398 Gene3D G3DSA:3.40.50.2300 58 215 9.1E-8 T 13-09-2016 THL1_RS14195 2bbd97333fb8b1ad1141ddd1333e509b 398 Gene3D G3DSA:3.40.50.2300 282 345 2.4E-4 T 13-09-2016 THL1_RS18185 923959564548d403a77f1ba9f36b2b28 294 Pfam PF13714 Phosphoenolpyruvate phosphomutase 14 254 4.5E-51 T 13-09-2016 THL1_RS18185 923959564548d403a77f1ba9f36b2b28 294 PANTHER PTHR21631 1 289 3.1E-150 T 13-09-2016 THL1_RS18185 923959564548d403a77f1ba9f36b2b28 294 Gene3D G3DSA:3.20.20.60 4 286 7.5E-99 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS18185 923959564548d403a77f1ba9f36b2b28 294 SUPERFAMILY SSF51621 4 289 3.05E-99 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS18185 923959564548d403a77f1ba9f36b2b28 294 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 7 291 2.2E-124 T 13-09-2016 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747|UniPathway: UPA00946 THL1_RS18185 923959564548d403a77f1ba9f36b2b28 294 PANTHER PTHR21631:SF4 1 289 3.1E-150 T 13-09-2016 THL1_RS18185 923959564548d403a77f1ba9f36b2b28 294 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 4 292 48.344 T 13-09-2016 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747|UniPathway: UPA00946 THL1_RS18185 923959564548d403a77f1ba9f36b2b28 294 ProSitePatterns PS00161 Isocitrate lyase signature. 121 126 - T 13-09-2016 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 THL1_RS00175 0ee6b72d25ebc7681bb5e4f56ddc0993 296 SUPERFAMILY SSF46785 4 86 1.09E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00175 0ee6b72d25ebc7681bb5e4f56ddc0993 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 6.3E-21 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS00175 0ee6b72d25ebc7681bb5e4f56ddc0993 296 PANTHER PTHR30537:SF16 1 294 3.2E-130 T 13-09-2016 THL1_RS00175 0ee6b72d25ebc7681bb5e4f56ddc0993 296 SUPERFAMILY SSF53850 95 294 8.51E-27 T 13-09-2016 THL1_RS00175 0ee6b72d25ebc7681bb5e4f56ddc0993 296 Gene3D G3DSA:3.40.190.10 164 264 1.3E-31 T 13-09-2016 THL1_RS00175 0ee6b72d25ebc7681bb5e4f56ddc0993 296 PANTHER PTHR30537 1 294 3.2E-130 T 13-09-2016 THL1_RS00175 0ee6b72d25ebc7681bb5e4f56ddc0993 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 7.4E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS00175 0ee6b72d25ebc7681bb5e4f56ddc0993 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 7.4E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS00175 0ee6b72d25ebc7681bb5e4f56ddc0993 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 7.4E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS00175 0ee6b72d25ebc7681bb5e4f56ddc0993 296 Gene3D G3DSA:1.10.10.10 2 86 1.7E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00175 0ee6b72d25ebc7681bb5e4f56ddc0993 296 Pfam PF03466 LysR substrate binding domain 96 293 2.4E-22 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS26695 d36759398e0d1b089307d1bfb7c4bb75 155 PANTHER PTHR36918:SF1 1 152 1.1E-80 T 13-09-2016 THL1_RS26695 d36759398e0d1b089307d1bfb7c4bb75 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 126 144 4.1E-37 T 13-09-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THL1_RS26695 d36759398e0d1b089307d1bfb7c4bb75 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 100 122 4.1E-37 T 13-09-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THL1_RS26695 d36759398e0d1b089307d1bfb7c4bb75 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 76 96 4.1E-37 T 13-09-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THL1_RS26695 d36759398e0d1b089307d1bfb7c4bb75 155 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 16 33 4.1E-37 T 13-09-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THL1_RS26695 d36759398e0d1b089307d1bfb7c4bb75 155 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 10 143 1.2E-53 T 13-09-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THL1_RS26695 d36759398e0d1b089307d1bfb7c4bb75 155 Pfam PF02556 Preprotein translocase subunit SecB 9 145 6.2E-54 T 13-09-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THL1_RS26695 d36759398e0d1b089307d1bfb7c4bb75 155 PANTHER PTHR36918 1 152 1.1E-80 T 13-09-2016 THL1_RS26695 d36759398e0d1b089307d1bfb7c4bb75 155 Gene3D G3DSA:3.10.420.10 7 153 8.5E-57 T 13-09-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THL1_RS26695 d36759398e0d1b089307d1bfb7c4bb75 155 SUPERFAMILY SSF54611 4 144 1.31E-52 T 13-09-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THL1_RS26695 d36759398e0d1b089307d1bfb7c4bb75 155 Hamap MF_00821 Protein-export protein SecB [secB]. 1 148 32.481 T 13-09-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THL1_RS06960 7dad0c409918aed79e516487c58bff92 336 Pfam PF10974 Protein of unknown function (DUF2804) 20 335 1.4E-76 T 13-09-2016 IPR021243 Protein of unknown function DUF2804 THL1_RS06960 7dad0c409918aed79e516487c58bff92 336 PANTHER PTHR35868 15 336 4.3E-100 T 13-09-2016 THL1_RS06960 7dad0c409918aed79e516487c58bff92 336 PANTHER PTHR35868:SF3 15 336 4.3E-100 T 13-09-2016 THL1_RS08575 93b78f39327a12d4d39669517ce9fb1c 295 Gene3D G3DSA:3.40.50.720 7 168 8.0E-56 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS08575 93b78f39327a12d4d39669517ce9fb1c 295 PANTHER PTHR22981 1 293 3.3E-156 T 13-09-2016 THL1_RS08575 93b78f39327a12d4d39669517ce9fb1c 295 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 167 1.5E-48 T 13-09-2016 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 THL1_RS08575 93b78f39327a12d4d39669517ce9fb1c 295 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 170 291 5.1E-25 T 13-09-2016 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 THL1_RS08575 93b78f39327a12d4d39669517ce9fb1c 295 SUPERFAMILY SSF51735 6 167 9.03E-44 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS08575 93b78f39327a12d4d39669517ce9fb1c 295 SUPERFAMILY SSF48179 168 293 1.7E-26 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS08575 93b78f39327a12d4d39669517ce9fb1c 295 PIRSF PIRSF000103 2 294 1.7E-73 T 13-09-2016 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 THL1_RS08575 93b78f39327a12d4d39669517ce9fb1c 295 PANTHER PTHR22981:SF48 1 293 3.3E-156 T 13-09-2016 THL1_RS08575 93b78f39327a12d4d39669517ce9fb1c 295 Gene3D G3DSA:1.10.1040.10 170 293 6.4E-29 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS18150 98c8ca53c0849588ab9ba652043c00a5 162 TIGRFAM TIGR01935 NOT-MenG: RraA family 5 154 2.5E-73 T 13-09-2016 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 THL1_RS18150 98c8ca53c0849588ab9ba652043c00a5 162 SUPERFAMILY SSF89562 3 158 5.76E-53 T 13-09-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein THL1_RS18150 98c8ca53c0849588ab9ba652043c00a5 162 Gene3D G3DSA:3.50.30.40 1 158 4.7E-58 T 13-09-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein THL1_RS18150 98c8ca53c0849588ab9ba652043c00a5 162 PANTHER PTHR33254:SF7 1 160 1.7E-100 T 13-09-2016 THL1_RS18150 98c8ca53c0849588ab9ba652043c00a5 162 Pfam PF03737 Demethylmenaquinone methyltransferase 5 153 2.7E-46 T 13-09-2016 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein THL1_RS18150 98c8ca53c0849588ab9ba652043c00a5 162 PANTHER PTHR33254 1 160 1.7E-100 T 13-09-2016 THL1_RS23165 68d872657f32bd4c359d38b235267f2e 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 254 8.9E-50 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS23165 68d872657f32bd4c359d38b235267f2e 257 PANTHER PTHR11941 3 253 7.4E-96 T 13-09-2016 THL1_RS23165 68d872657f32bd4c359d38b235267f2e 257 Gene3D G3DSA:3.90.226.10 2 253 1.3E-73 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS23165 68d872657f32bd4c359d38b235267f2e 257 SUPERFAMILY SSF52096 1 255 2.28E-72 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS23165 68d872657f32bd4c359d38b235267f2e 257 PANTHER PTHR11941:SF17 3 253 7.4E-96 T 13-09-2016 THL1_RS26480 ed6e96796d00bfdcecc1e4666dd52f7f 263 SUPERFAMILY SSF53850 1 255 1.09E-67 T 13-09-2016 THL1_RS26480 ed6e96796d00bfdcecc1e4666dd52f7f 263 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 33 254 3.3E-57 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS26480 ed6e96796d00bfdcecc1e4666dd52f7f 263 PANTHER PTHR18966 21 258 1.8E-80 T 13-09-2016 THL1_RS26480 ed6e96796d00bfdcecc1e4666dd52f7f 263 SMART SM00079 32 255 8.2E-5 T 13-09-2016 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 THL1_RS26480 ed6e96796d00bfdcecc1e4666dd52f7f 263 SMART SM00062 32 256 2.7E-60 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS26480 ed6e96796d00bfdcecc1e4666dd52f7f 263 PANTHER PTHR18966:SF152 21 258 1.8E-80 T 13-09-2016 THL1_RS26480 ed6e96796d00bfdcecc1e4666dd52f7f 263 Gene3D G3DSA:3.40.190.10 29 109 6.8E-39 T 13-09-2016 THL1_RS26480 ed6e96796d00bfdcecc1e4666dd52f7f 263 Gene3D G3DSA:3.40.190.10 216 255 6.8E-39 T 13-09-2016 THL1_RS26480 ed6e96796d00bfdcecc1e4666dd52f7f 263 Gene3D G3DSA:3.40.190.10 110 215 7.7E-17 T 13-09-2016 THL1_RS12230 d643ef5b3a20e1fb82e53e5571eb341b 241 SUPERFAMILY SSF55846 49 238 7.72E-28 T 13-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 THL1_RS12230 d643ef5b3a20e1fb82e53e5571eb341b 241 SMART SM00701 47 182 2.1E-4 T 13-09-2016 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 THL1_RS12230 d643ef5b3a20e1fb82e53e5571eb341b 241 Gene3D G3DSA:3.40.80.10 48 232 1.9E-33 T 13-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 THL1_RS12230 d643ef5b3a20e1fb82e53e5571eb341b 241 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 71 217 7.7E-7 T 13-09-2016 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 THL1_RS26540 f9ce7450b146e62734adef9804457d89 556 Pfam PF01175 Urocanase 9 544 5.7E-262 T 13-09-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 THL1_RS26540 f9ce7450b146e62734adef9804457d89 556 TIGRFAM TIGR01228 hutU: urocanate hydratase 8 551 0.0 T 13-09-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 THL1_RS26540 f9ce7450b146e62734adef9804457d89 556 PIRSF PIRSF001423 1 556 3.1E-296 T 13-09-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 THL1_RS26540 f9ce7450b146e62734adef9804457d89 556 PANTHER PTHR12216 1 552 0.0 T 13-09-2016 THL1_RS26540 f9ce7450b146e62734adef9804457d89 556 Hamap MF_00577 Urocanate hydratase [hutU]. 2 553 50.668 T 13-09-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 THL1_RS26540 f9ce7450b146e62734adef9804457d89 556 SUPERFAMILY SSF111326 4 552 4.05E-263 T 13-09-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 THL1_RS26540 f9ce7450b146e62734adef9804457d89 556 PANTHER PTHR12216:SF3 1 552 0.0 T 13-09-2016 THL1_RS26540 f9ce7450b146e62734adef9804457d89 556 Gene3D G3DSA:3.40.50.10730 139 346 4.5E-96 T 13-09-2016 THL1_RS26540 f9ce7450b146e62734adef9804457d89 556 Gene3D G3DSA:3.40.1770.10 5 138 3.4E-164 T 13-09-2016 THL1_RS26540 f9ce7450b146e62734adef9804457d89 556 Gene3D G3DSA:3.40.1770.10 357 552 3.4E-164 T 13-09-2016 THL1_RS26540 f9ce7450b146e62734adef9804457d89 556 ProSitePatterns PS01233 Urocanase signature. 439 454 - T 13-09-2016 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 THL1_RS23705 8054fb034c7c6be2f986f790475c5e12 339 Pfam PF12833 Helix-turn-helix domain 261 337 2.4E-18 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS23705 8054fb034c7c6be2f986f790475c5e12 339 Gene3D G3DSA:1.10.10.60 290 338 6.0E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS23705 8054fb034c7c6be2f986f790475c5e12 339 PANTHER PTHR11019:SF52 192 338 9.9E-37 T 13-09-2016 THL1_RS23705 8054fb034c7c6be2f986f790475c5e12 339 SMART SM00342 254 336 3.9E-24 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS23705 8054fb034c7c6be2f986f790475c5e12 339 SUPERFAMILY SSF46689 290 338 1.79E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS23705 8054fb034c7c6be2f986f790475c5e12 339 PANTHER PTHR11019 192 338 9.9E-37 T 13-09-2016 THL1_RS23705 8054fb034c7c6be2f986f790475c5e12 339 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 28 211 7.8E-38 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS23705 8054fb034c7c6be2f986f790475c5e12 339 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 305 320 2.0E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS23705 8054fb034c7c6be2f986f790475c5e12 339 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 320 336 2.0E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS26770 8596c371a837ed47678d3c4b9909a475 743 PANTHER PTHR30441:SF4 1 137 3.1E-220 T 13-09-2016 THL1_RS26770 8596c371a837ed47678d3c4b9909a475 743 PANTHER PTHR30441:SF4 154 743 3.1E-220 T 13-09-2016 THL1_RS26770 8596c371a837ed47678d3c4b9909a475 743 PANTHER PTHR30441 154 743 3.1E-220 T 13-09-2016 THL1_RS26770 8596c371a837ed47678d3c4b9909a475 743 PANTHER PTHR30441 1 137 3.1E-220 T 13-09-2016 THL1_RS26770 8596c371a837ed47678d3c4b9909a475 743 Pfam PF05170 AsmA family 1 629 1.8E-142 T 13-09-2016 IPR007844 AsmA THL1_RS05330 e378f5a63e9fd62ccb628377f12d13f0 480 PANTHER PTHR30624 15 480 5.4E-251 T 13-09-2016 THL1_RS05330 e378f5a63e9fd62ccb628377f12d13f0 480 Pfam PF01523 Putative modulator of DNA gyrase 38 330 4.3E-68 T 13-09-2016 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS05330 e378f5a63e9fd62ccb628377f12d13f0 480 SUPERFAMILY SSF111283 22 478 5.49E-134 T 13-09-2016 THL1_RS05330 e378f5a63e9fd62ccb628377f12d13f0 480 PANTHER PTHR30624:SF4 15 480 5.4E-251 T 13-09-2016 THL1_RS05330 e378f5a63e9fd62ccb628377f12d13f0 480 PIRSF PIRSF004919 18 479 5.9E-139 T 13-09-2016 IPR025502 TldD KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS16750 2e9192153a276c89409ac6426a1602f9 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 217 1.9E-22 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS16750 2e9192153a276c89409ac6426a1602f9 222 SUPERFAMILY SSF52172 1 118 1.35E-36 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS16750 2e9192153a276c89409ac6426a1602f9 222 Pfam PF00072 Response regulator receiver domain 4 112 1.9E-23 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS16750 2e9192153a276c89409ac6426a1602f9 222 Gene3D G3DSA:3.40.50.2300 1 124 1.8E-34 T 13-09-2016 THL1_RS16750 2e9192153a276c89409ac6426a1602f9 222 PANTHER PTHR26402:SF279 1 217 2.4E-126 T 13-09-2016 THL1_RS16750 2e9192153a276c89409ac6426a1602f9 222 PANTHER PTHR26402 1 217 2.4E-126 T 13-09-2016 THL1_RS16750 2e9192153a276c89409ac6426a1602f9 222 SUPERFAMILY SSF46894 123 218 3.97E-26 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS16750 2e9192153a276c89409ac6426a1602f9 222 SMART SM00448 1 112 1.9E-38 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS16750 2e9192153a276c89409ac6426a1602f9 222 SMART SM00862 146 217 3.3E-27 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS16750 2e9192153a276c89409ac6426a1602f9 222 Gene3D G3DSA:1.10.10.10 125 218 9.6E-30 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS03880 06468a6f4ebef12236f03f71843484a7 217 TIGRFAM TIGR02281 clan_AA_DTGA: clan AA aspartic protease, TIGR02281 family 97 214 1.2E-38 T 13-09-2016 IPR011969 Clan AA aspartic peptidase, C-terminal THL1_RS03880 06468a6f4ebef12236f03f71843484a7 217 Pfam PF13975 gag-polyprotein putative aspartyl protease 110 201 8.9E-26 T 13-09-2016 THL1_RS03880 06468a6f4ebef12236f03f71843484a7 217 PANTHER PTHR41535 5 214 8.5E-43 T 13-09-2016 THL1_RS03880 06468a6f4ebef12236f03f71843484a7 217 PANTHER PTHR41535:SF1 5 214 8.5E-43 T 13-09-2016 THL1_RS03880 06468a6f4ebef12236f03f71843484a7 217 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 120 131 - T 13-09-2016 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 THL1_RS03880 06468a6f4ebef12236f03f71843484a7 217 SUPERFAMILY SSF50630 103 204 3.23E-20 T 13-09-2016 IPR021109 Aspartic peptidase domain THL1_RS03550 9d6e41007eea974067df6090e2c641bd 110 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 13-09-2016 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03550 9d6e41007eea974067df6090e2c641bd 110 Gene3D G3DSA:3.90.470.10 1 109 1.7E-42 T 13-09-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 THL1_RS03550 9d6e41007eea974067df6090e2c641bd 110 PANTHER PTHR13501 1 109 1.2E-49 T 13-09-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 THL1_RS03550 9d6e41007eea974067df6090e2c641bd 110 SUPERFAMILY SSF54843 1 109 4.71E-42 T 13-09-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 THL1_RS03550 9d6e41007eea974067df6090e2c641bd 110 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 27.841 T 13-09-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 THL1_RS03550 9d6e41007eea974067df6090e2c641bd 110 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 6.1E-45 T 13-09-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 THL1_RS03550 9d6e41007eea974067df6090e2c641bd 110 Pfam PF00237 Ribosomal protein L22p/L17e 9 107 8.5E-34 T 13-09-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 THL1_RS01285 6db10429023ef8655026fc05d5e26b94 662 Gene3D G3DSA:3.40.50.300 59 108 2.2E-15 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01285 6db10429023ef8655026fc05d5e26b94 662 Gene3D G3DSA:3.40.50.300 206 317 2.2E-15 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01285 6db10429023ef8655026fc05d5e26b94 662 Pfam PF00350 Dynamin family 59 273 2.4E-13 T 13-09-2016 IPR022812 Dynamin superfamily THL1_RS01285 6db10429023ef8655026fc05d5e26b94 662 SUPERFAMILY SSF52540 45 343 2.43E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS02125 5ca9922ac7971b9d642e5fc19d1e273d 725 Gene3D G3DSA:2.170.170.11 298 335 9.4E-72 T 13-09-2016 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 THL1_RS02125 5ca9922ac7971b9d642e5fc19d1e273d 725 Gene3D G3DSA:2.170.170.11 136 264 9.4E-72 T 13-09-2016 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 THL1_RS02125 5ca9922ac7971b9d642e5fc19d1e273d 725 Pfam PF01274 Malate synthase 18 697 3.8E-197 T 13-09-2016 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 THL1_RS02125 5ca9922ac7971b9d642e5fc19d1e273d 725 Gene3D G3DSA:3.20.20.360 89 135 8.4E-150 T 13-09-2016 THL1_RS02125 5ca9922ac7971b9d642e5fc19d1e273d 725 Gene3D G3DSA:3.20.20.360 336 588 8.4E-150 T 13-09-2016 THL1_RS02125 5ca9922ac7971b9d642e5fc19d1e273d 725 Gene3D G3DSA:3.20.20.360 266 296 8.4E-150 T 13-09-2016 THL1_RS02125 5ca9922ac7971b9d642e5fc19d1e273d 725 PANTHER PTHR21631 501 724 2.8E-155 T 13-09-2016 THL1_RS02125 5ca9922ac7971b9d642e5fc19d1e273d 725 PANTHER PTHR21631 33 41 2.8E-155 T 13-09-2016 THL1_RS02125 5ca9922ac7971b9d642e5fc19d1e273d 725 SUPERFAMILY SSF51645 2 723 0.0 T 13-09-2016 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 THL1_RS02125 5ca9922ac7971b9d642e5fc19d1e273d 725 Hamap MF_00641 Malate synthase G [glcB]. 1 725 423.31 T 13-09-2016 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 THL1_RS02125 5ca9922ac7971b9d642e5fc19d1e273d 725 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 723 0.0 T 13-09-2016 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00703 THL1_RS02125 5ca9922ac7971b9d642e5fc19d1e273d 725 Gene3D G3DSA:1.20.1220.12 590 723 5.2E-74 T 13-09-2016 THL1_RS02125 5ca9922ac7971b9d642e5fc19d1e273d 725 PANTHER PTHR21631:SF7 501 724 2.8E-155 T 13-09-2016 THL1_RS02125 5ca9922ac7971b9d642e5fc19d1e273d 725 PANTHER PTHR21631:SF7 33 41 2.8E-155 T 13-09-2016 THL1_RS02125 5ca9922ac7971b9d642e5fc19d1e273d 725 Gene3D G3DSA:1.10.1860.10 1 88 2.2E-38 T 13-09-2016 THL1_RS14595 4e943a19d0618560085d3c145088b463 296 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 134 164 - T 13-09-2016 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS14595 4e943a19d0618560085d3c145088b463 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 129 146 4.0E-21 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS14595 4e943a19d0618560085d3c145088b463 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 72 90 4.0E-21 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS14595 4e943a19d0618560085d3c145088b463 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 36 57 4.0E-21 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS14595 4e943a19d0618560085d3c145088b463 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 104 120 4.0E-21 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS14595 4e943a19d0618560085d3c145088b463 296 PANTHER PTHR12128 1 291 2.2E-83 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS14595 4e943a19d0618560085d3c145088b463 296 Pfam PF00701 Dihydrodipicolinate synthetase family 3 290 6.8E-68 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS14595 4e943a19d0618560085d3c145088b463 296 Gene3D G3DSA:3.20.20.70 1 291 1.5E-88 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS14595 4e943a19d0618560085d3c145088b463 296 SMART SM01130 2 292 8.1E-89 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS14595 4e943a19d0618560085d3c145088b463 296 PANTHER PTHR12128:SF34 1 291 2.2E-83 T 13-09-2016 THL1_RS14595 4e943a19d0618560085d3c145088b463 296 SUPERFAMILY SSF51569 1 290 2.3E-82 T 13-09-2016 THL1_RS14595 4e943a19d0618560085d3c145088b463 296 PIRSF PIRSF001365 1 296 2.0E-81 T 13-09-2016 IPR002220 DapA-like GO:0008152|GO:0016829 THL1_RS25655 e9e42ffcecab3fc2636fc117bf92f31f 304 SUPERFAMILY SSF51695 41 292 4.45E-68 T 13-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 THL1_RS25655 e9e42ffcecab3fc2636fc117bf92f31f 304 PANTHER PTHR23344 1 292 1.6E-72 T 13-09-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 THL1_RS25655 e9e42ffcecab3fc2636fc117bf92f31f 304 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 47 286 1.1E-38 T 13-09-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 THL1_RS25655 e9e42ffcecab3fc2636fc117bf92f31f 304 Gene3D G3DSA:3.20.20.190 39 294 1.4E-69 T 13-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 THL1_RS20785 621242477ef6ec7918ab7dd0e7288e89 138 PANTHER PTHR30574 1 138 9.1E-39 T 13-09-2016 THL1_RS20785 621242477ef6ec7918ab7dd0e7288e89 138 PANTHER PTHR30574:SF1 1 138 9.1E-39 T 13-09-2016 THL1_RS20000 a54ef7b9ed4457114f515f4ae767d411 173 SUPERFAMILY SSF88659 96 163 7.2E-11 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS20000 a54ef7b9ed4457114f515f4ae767d411 173 Pfam PF04542 Sigma-70 region 2 16 72 6.1E-9 T 13-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS20000 a54ef7b9ed4457114f515f4ae767d411 173 PANTHER PTHR30173 6 170 6.1E-27 T 13-09-2016 THL1_RS20000 a54ef7b9ed4457114f515f4ae767d411 173 Gene3D G3DSA:1.10.1740.10 6 74 1.0E-12 T 13-09-2016 THL1_RS20000 a54ef7b9ed4457114f515f4ae767d411 173 Gene3D G3DSA:1.10.10.10 106 157 1.6E-9 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20000 a54ef7b9ed4457114f515f4ae767d411 173 SUPERFAMILY SSF88946 7 90 8.63E-13 T 13-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS20000 a54ef7b9ed4457114f515f4ae767d411 173 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 162 1.0E-22 T 13-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS20000 a54ef7b9ed4457114f515f4ae767d411 173 Pfam PF08281 Sigma-70, region 4 110 157 1.6E-12 T 13-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS00355 0113dbb8b3d15f516c5e0c1f37b89f7a 316 Hamap MF_00301 Homoserine kinase [thrB]. 1 316 139.576 T 13-09-2016 IPR005280 Homoserine kinase ThrB GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702|UniPathway: UPA00050 THL1_RS00355 0113dbb8b3d15f516c5e0c1f37b89f7a 316 Gene3D G3DSA:3.30.200.20 1 102 2.1E-34 T 13-09-2016 THL1_RS00355 0113dbb8b3d15f516c5e0c1f37b89f7a 316 Gene3D G3DSA:3.90.1200.10 105 307 9.4E-55 T 13-09-2016 THL1_RS00355 0113dbb8b3d15f516c5e0c1f37b89f7a 316 Pfam PF01636 Phosphotransferase enzyme family 28 255 8.5E-36 T 13-09-2016 IPR002575 Aminoglycoside phosphotransferase THL1_RS00355 0113dbb8b3d15f516c5e0c1f37b89f7a 316 SUPERFAMILY SSF56112 5 306 6.27E-65 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS00355 0113dbb8b3d15f516c5e0c1f37b89f7a 316 PANTHER PTHR21064 8 292 5.8E-46 T 13-09-2016 THL1_RS00355 0113dbb8b3d15f516c5e0c1f37b89f7a 316 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 303 3.9E-84 T 13-09-2016 IPR005280 Homoserine kinase ThrB GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702|UniPathway: UPA00050 THL1_RS04440 38d4e498f069362746d2419320b6c2d9 356 Gene3D G3DSA:3.40.50.300 12 218 1.9E-72 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04440 38d4e498f069362746d2419320b6c2d9 356 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 15 200 4.0E-54 T 13-09-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain THL1_RS04440 38d4e498f069362746d2419320b6c2d9 356 SMART SM00833 261 354 3.2E-17 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS04440 38d4e498f069362746d2419320b6c2d9 356 SUPERFAMILY SSF90002 261 354 2.22E-25 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS04440 38d4e498f069362746d2419320b6c2d9 356 PANTHER PTHR13748 10 356 1.3E-132 T 13-09-2016 THL1_RS04440 38d4e498f069362746d2419320b6c2d9 356 Gene3D G3DSA:3.30.1220.10 236 355 2.6E-37 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS04440 38d4e498f069362746d2419320b6c2d9 356 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 261 354 2.0E-22 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS04440 38d4e498f069362746d2419320b6c2d9 356 PANTHER PTHR13748:SF43 10 356 1.3E-132 T 13-09-2016 THL1_RS04440 38d4e498f069362746d2419320b6c2d9 356 SUPERFAMILY SSF52540 12 221 8.29E-37 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07340 5d6417db9016326a9c076bbf8b2d33a8 307 Gene3D G3DSA:3.40.50.720 143 270 4.4E-54 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07340 5d6417db9016326a9c076bbf8b2d33a8 307 Gene3D G3DSA:3.40.192.10 11 142 6.4E-48 T 13-09-2016 THL1_RS07340 5d6417db9016326a9c076bbf8b2d33a8 307 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 266 274 - T 13-09-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07340 5d6417db9016326a9c076bbf8b2d33a8 307 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 79 104 - T 13-09-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07340 5d6417db9016326a9c076bbf8b2d33a8 307 SUPERFAMILY SSF51735 126 287 1.76E-52 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07340 5d6417db9016326a9c076bbf8b2d33a8 307 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 127 288 2.6E-68 T 13-09-2016 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07340 5d6417db9016326a9c076bbf8b2d33a8 307 PANTHER PTHR10025 8 289 9.8E-154 T 13-09-2016 THL1_RS07340 5d6417db9016326a9c076bbf8b2d33a8 307 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 113 134 9.4E-81 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07340 5d6417db9016326a9c076bbf8b2d33a8 307 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 245 261 9.4E-81 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07340 5d6417db9016326a9c076bbf8b2d33a8 307 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 78 105 9.4E-81 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07340 5d6417db9016326a9c076bbf8b2d33a8 307 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 158 178 9.4E-81 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07340 5d6417db9016326a9c076bbf8b2d33a8 307 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 262 280 9.4E-81 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07340 5d6417db9016326a9c076bbf8b2d33a8 307 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 207 236 9.4E-81 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07340 5d6417db9016326a9c076bbf8b2d33a8 307 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 37 59 9.4E-81 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07340 5d6417db9016326a9c076bbf8b2d33a8 307 Hamap MF_01576 Bifunctional protein FolD [folD]. 7 289 38.548 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS07340 5d6417db9016326a9c076bbf8b2d33a8 307 SUPERFAMILY SSF53223 7 125 9.02E-39 T 13-09-2016 THL1_RS07340 5d6417db9016326a9c076bbf8b2d33a8 307 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 9 124 4.6E-39 T 13-09-2016 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS12245 c6677f14fa18211175a2572432d1261a 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 140 159 1.0E-37 T 13-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 THL1_RS12245 c6677f14fa18211175a2572432d1261a 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 338 357 1.0E-37 T 13-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 THL1_RS12245 c6677f14fa18211175a2572432d1261a 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 390 416 1.0E-37 T 13-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 THL1_RS12245 c6677f14fa18211175a2572432d1261a 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 250 274 1.0E-37 T 13-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 THL1_RS12245 c6677f14fa18211175a2572432d1261a 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 175 199 1.0E-37 T 13-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 THL1_RS12245 c6677f14fa18211175a2572432d1261a 508 PANTHER PTHR22773 1 491 4.3E-186 T 13-09-2016 THL1_RS12245 c6677f14fa18211175a2572432d1261a 508 PANTHER PTHR22773:SF40 1 491 4.3E-186 T 13-09-2016 THL1_RS12245 c6677f14fa18211175a2572432d1261a 508 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 3 495 2.6E-172 T 13-09-2016 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 THL1_RS12245 c6677f14fa18211175a2572432d1261a 508 Pfam PF00361 Proton-conducting membrane transporter 134 432 2.3E-72 T 13-09-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 THL1_RS05305 23a809e520adbb559ad670ce801c019f 162 PIRSF PIRSF018472 1 162 5.5E-53 T 13-09-2016 IPR026034 Cell shape-determining protein MreD, proteobacterial type THL1_RS05305 23a809e520adbb559ad670ce801c019f 162 PANTHER PTHR37484 1 162 5.4E-62 T 13-09-2016 THL1_RS05305 23a809e520adbb559ad670ce801c019f 162 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 8 152 9.2E-36 T 13-09-2016 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 THL1_RS05305 23a809e520adbb559ad670ce801c019f 162 Pfam PF04093 rod shape-determining protein MreD 5 152 8.8E-37 T 13-09-2016 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 THL1_RS07835 2861c87865a182316a766fa95de349b7 343 PANTHER PTHR33442 1 334 1.4E-110 T 13-09-2016 THL1_RS07835 2861c87865a182316a766fa95de349b7 343 PANTHER PTHR33442:SF2 1 334 1.4E-110 T 13-09-2016 THL1_RS07835 2861c87865a182316a766fa95de349b7 343 Gene3D G3DSA:3.10.310.10 2 153 2.1E-61 T 13-09-2016 THL1_RS07835 2861c87865a182316a766fa95de349b7 343 Pfam PF05544 Proline racemase 8 331 1.2E-113 T 13-09-2016 IPR008794 Proline racemase family THL1_RS07835 2861c87865a182316a766fa95de349b7 343 SUPERFAMILY SSF54506 2 331 2.36E-101 T 13-09-2016 THL1_RS07835 2861c87865a182316a766fa95de349b7 343 PIRSF PIRSF029792 1 334 5.0E-117 T 13-09-2016 IPR008794 Proline racemase family THL1_RS07835 2861c87865a182316a766fa95de349b7 343 Gene3D G3DSA:3.10.310.10 154 321 1.0E-57 T 13-09-2016 THL1_RS17455 349a35ad2050f8a0c2f401bcda219f96 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 257 2.3E-83 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS17455 349a35ad2050f8a0c2f401bcda219f96 258 Gene3D G3DSA:3.90.226.10 1 256 8.0E-97 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS17455 349a35ad2050f8a0c2f401bcda219f96 258 SUPERFAMILY SSF52096 1 258 1.41E-88 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS17455 349a35ad2050f8a0c2f401bcda219f96 258 PANTHER PTHR11941:SF54 1 255 2.0E-119 T 13-09-2016 THL1_RS17455 349a35ad2050f8a0c2f401bcda219f96 258 PANTHER PTHR11941 1 255 2.0E-119 T 13-09-2016 THL1_RS17455 349a35ad2050f8a0c2f401bcda219f96 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 13-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 Gene3D G3DSA:3.40.50.920 503 626 3.3E-36 T 13-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 PANTHER PTHR11624:SF20 248 626 2.7E-303 T 13-09-2016 THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 SUPERFAMILY SSF52922 498 626 6.02E-32 T 13-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 17 627 46.008 T 13-09-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 22 626 2.3E-266 T 13-09-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 Pfam PF02779 Transketolase, pyrimidine binding domain 326 486 3.0E-37 T 13-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 Pfam PF02780 Transketolase, C-terminal domain 502 618 2.8E-28 T 13-09-2016 IPR033248 Transketolase, C-terminal domain THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 PANTHER PTHR11624 248 626 2.7E-303 T 13-09-2016 IPR033247 Transketolase family THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 SMART SM00861 326 490 2.8E-63 T 13-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 PANTHER PTHR11624:SF20 31 225 2.7E-303 T 13-09-2016 THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 SUPERFAMILY SSF52518 14 206 7.54E-78 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 SUPERFAMILY SSF52518 250 388 7.54E-78 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 Gene3D G3DSA:3.40.50.970 249 341 4.6E-75 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 Gene3D G3DSA:3.40.50.970 33 208 4.6E-75 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 18 289 1.4E-120 T 13-09-2016 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 PANTHER PTHR11624 31 225 2.7E-303 T 13-09-2016 IPR033247 Transketolase family THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 SUPERFAMILY SSF52518 323 510 2.32E-56 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 Gene3D G3DSA:3.40.50.970 342 502 2.8E-31 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS03900 e72b4190af0f5382cdd28a44c5104287 631 ProSitePatterns PS00802 Transketolase signature 2. 432 448 - T 13-09-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 THL1_RS26355 2727310db86fe25989385176bd33fa27 740 SUPERFAMILY SSF52540 193 384 1.47E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26355 2727310db86fe25989385176bd33fa27 740 SMART SM00490 497 594 1.7E-7 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS26355 2727310db86fe25989385176bd33fa27 740 TIGRFAM TIGR00595 priA: primosomal protein N' 226 737 2.6E-185 T 13-09-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 THL1_RS26355 2727310db86fe25989385176bd33fa27 740 Pfam PF00270 DEAD/DEAH box helicase 208 370 2.0E-16 T 13-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THL1_RS26355 2727310db86fe25989385176bd33fa27 740 Hamap MF_00983 Probable primosomal protein N' [priA]. 9 739 25.115 T 13-09-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 THL1_RS26355 2727310db86fe25989385176bd33fa27 740 Gene3D G3DSA:3.40.50.300 498 638 1.3E-27 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26355 2727310db86fe25989385176bd33fa27 740 Gene3D G3DSA:3.40.50.300 412 433 1.3E-27 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26355 2727310db86fe25989385176bd33fa27 740 SMART SM00487 200 400 1.6E-24 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS26355 2727310db86fe25989385176bd33fa27 740 SUPERFAMILY SSF52540 413 439 3.09E-21 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26355 2727310db86fe25989385176bd33fa27 740 SUPERFAMILY SSF52540 500 623 3.09E-21 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26355 2727310db86fe25989385176bd33fa27 740 PANTHER PTHR30580 1 740 7.1E-273 T 13-09-2016 THL1_RS26355 2727310db86fe25989385176bd33fa27 740 Gene3D G3DSA:3.40.50.300 197 387 1.9E-41 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26355 2727310db86fe25989385176bd33fa27 740 Pfam PF00271 Helicase conserved C-terminal domain 522 593 2.7E-5 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS20330 f7c6b97191e090dd1927886d350b7d20 246 Pfam PF05857 TraX protein 17 243 2.5E-50 T 13-09-2016 IPR008875 TraX THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 PANTHER PTHR24322:SF635 10 138 5.2E-72 T 13-09-2016 THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 PANTHER PTHR24322:SF635 154 186 5.2E-72 T 13-09-2016 THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 SUPERFAMILY SSF51735 4 246 2.59E-83 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 245 5.8E-101 T 13-09-2016 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.5E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.5E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.5E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 185 7.9E-6 T 13-09-2016 THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 244 8.3E-64 T 13-09-2016 THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 Gene3D G3DSA:3.40.50.720 2 246 1.0E-86 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 4.5E-46 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.5E-46 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.5E-46 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.5E-46 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.5E-46 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.5E-46 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 PANTHER PTHR24322 10 138 5.2E-72 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18650 d9e55a7253a39436461a5964aaad4cc9 247 PANTHER PTHR24322 154 186 5.2E-72 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06985 22b01b3b78d9505d3afe487ae87a6d9b 593 Pfam PF00664 ABC transporter transmembrane region 26 310 8.1E-29 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS06985 22b01b3b78d9505d3afe487ae87a6d9b 593 PANTHER PTHR24221:SF233 3 590 0.0 T 13-09-2016 THL1_RS06985 22b01b3b78d9505d3afe487ae87a6d9b 593 Gene3D G3DSA:3.40.50.300 357 589 3.3E-75 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06985 22b01b3b78d9505d3afe487ae87a6d9b 593 Gene3D G3DSA:1.20.1560.10 10 344 4.5E-53 T 13-09-2016 THL1_RS06985 22b01b3b78d9505d3afe487ae87a6d9b 593 SUPERFAMILY SSF90123 10 339 7.19E-55 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS06985 22b01b3b78d9505d3afe487ae87a6d9b 593 PANTHER PTHR24221 3 590 0.0 T 13-09-2016 THL1_RS06985 22b01b3b78d9505d3afe487ae87a6d9b 593 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS06985 22b01b3b78d9505d3afe487ae87a6d9b 593 Pfam PF00005 ABC transporter 372 520 4.6E-32 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS06985 22b01b3b78d9505d3afe487ae87a6d9b 593 SUPERFAMILY SSF52540 354 588 7.99E-80 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06985 22b01b3b78d9505d3afe487ae87a6d9b 593 SMART SM00382 381 572 3.0E-13 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS10105 724c90e9be2a69036e054e9c5b5c985a 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 165 183 6.0E-38 T 13-09-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS10105 724c90e9be2a69036e054e9c5b5c985a 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 253 262 6.0E-38 T 13-09-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS10105 724c90e9be2a69036e054e9c5b5c985a 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 131 145 6.0E-38 T 13-09-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS10105 724c90e9be2a69036e054e9c5b5c985a 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 231 242 6.0E-38 T 13-09-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS10105 724c90e9be2a69036e054e9c5b5c985a 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 202 219 6.0E-38 T 13-09-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS10105 724c90e9be2a69036e054e9c5b5c985a 290 PANTHER PTHR22855:SF17 3 287 2.0E-163 T 13-09-2016 THL1_RS10105 724c90e9be2a69036e054e9c5b5c985a 290 Pfam PF01039 Carboxyl transferase domain 100 241 2.0E-15 T 13-09-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS10105 724c90e9be2a69036e054e9c5b5c985a 290 PANTHER PTHR22855 3 287 2.0E-163 T 13-09-2016 THL1_RS10105 724c90e9be2a69036e054e9c5b5c985a 290 Gene3D G3DSA:3.90.226.10 20 283 3.0E-73 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS10105 724c90e9be2a69036e054e9c5b5c985a 290 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 2 283 37.731 T 13-09-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS10105 724c90e9be2a69036e054e9c5b5c985a 290 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 15 285 6.0E-130 T 13-09-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS10105 724c90e9be2a69036e054e9c5b5c985a 290 SUPERFAMILY SSF52096 27 283 3.51E-88 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS12690 b802ce2a24d8ae57100f5534506931d3 269 Gene3D G3DSA:3.40.50.720 115 247 6.7E-35 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS12690 b802ce2a24d8ae57100f5534506931d3 269 PANTHER PTHR21089:SF6 2 255 1.4E-69 T 13-09-2016 THL1_RS12690 b802ce2a24d8ae57100f5534506931d3 269 Gene3D G3DSA:3.40.192.10 2 114 3.5E-29 T 13-09-2016 THL1_RS12690 b802ce2a24d8ae57100f5534506931d3 269 SUPERFAMILY SSF53223 2 106 1.27E-24 T 13-09-2016 THL1_RS12690 b802ce2a24d8ae57100f5534506931d3 269 SUPERFAMILY SSF51735 108 254 4.73E-30 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS12690 b802ce2a24d8ae57100f5534506931d3 269 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 11 94 3.7E-19 T 13-09-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS12690 b802ce2a24d8ae57100f5534506931d3 269 PANTHER PTHR21089 2 255 1.4E-69 T 13-09-2016 THL1_RS12690 b802ce2a24d8ae57100f5534506931d3 269 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 124 195 3.1E-7 T 13-09-2016 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 Gene3D G3DSA:3.20.20.450 607 852 9.8E-98 T 13-09-2016 IPR001633 EAL domain THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 PANTHER PTHR33121 228 265 6.6E-77 T 13-09-2016 THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 Pfam PF00563 EAL domain 611 840 3.7E-73 T 13-09-2016 IPR001633 EAL domain THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 Gene3D G3DSA:3.30.450.20 300 418 7.3E-13 T 13-09-2016 THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 Pfam PF05228 CHASE4 domain 65 226 2.1E-19 T 13-09-2016 IPR007892 CHASE4 THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 PANTHER PTHR33121 558 854 6.6E-77 T 13-09-2016 THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 429 591 2.3E-25 T 13-09-2016 IPR000160 GGDEF domain THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 SMART SM00091 308 373 4.7E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 SUPERFAMILY SSF141868 611 853 9.29E-89 T 13-09-2016 IPR001633 EAL domain THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 Gene3D G3DSA:3.30.70.270 434 602 1.9E-40 T 13-09-2016 THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 Pfam PF00990 Diguanylate cyclase, GGDEF domain 433 588 3.3E-35 T 13-09-2016 IPR000160 GGDEF domain THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 304 425 1.4E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 SMART SM00052 604 845 5.9E-117 T 13-09-2016 IPR001633 EAL domain THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 SMART SM00267 421 594 1.9E-39 T 13-09-2016 IPR000160 GGDEF domain THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 SUPERFAMILY SSF55073 437 596 1.02E-35 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 PANTHER PTHR33121:SF13 558 854 6.6E-77 T 13-09-2016 THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 PANTHER PTHR33121:SF13 228 265 6.6E-77 T 13-09-2016 THL1_RS12815 16ad6be8875fd615662398443d6ca749 862 SUPERFAMILY SSF55785 301 419 3.66E-14 T 13-09-2016 IPR000014 PAS domain THL1_RS22010 abd7bea4c395e4a6ec831e0f08489a75 180 PANTHER PTHR30461:SF9 1 178 8.7E-46 T 13-09-2016 THL1_RS22010 abd7bea4c395e4a6ec831e0f08489a75 180 ProSitePatterns PS00397 Site-specific recombinases active site. 6 14 - T 13-09-2016 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 THL1_RS22010 abd7bea4c395e4a6ec831e0f08489a75 180 PANTHER PTHR30461 1 178 8.7E-46 T 13-09-2016 THL1_RS22010 abd7bea4c395e4a6ec831e0f08489a75 180 ProSitePatterns PS00398 Site-specific recombinases signature 2. 53 65 - T 13-09-2016 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 THL1_RS22010 abd7bea4c395e4a6ec831e0f08489a75 180 Pfam PF05225 helix-turn-helix, Psq domain 146 179 1.5E-5 T 13-09-2016 IPR007889 DNA binding HTH domain, Psq-type GO:0003677 THL1_RS22010 abd7bea4c395e4a6ec831e0f08489a75 180 Gene3D G3DSA:3.40.50.1390 3 121 1.2E-40 T 13-09-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 THL1_RS22010 abd7bea4c395e4a6ec831e0f08489a75 180 Pfam PF00239 Resolvase, N terminal domain 4 137 2.3E-40 T 13-09-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 THL1_RS22010 abd7bea4c395e4a6ec831e0f08489a75 180 Gene3D G3DSA:1.10.10.60 137 178 5.5E-6 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS22010 abd7bea4c395e4a6ec831e0f08489a75 180 SUPERFAMILY SSF53041 1 137 1.96E-43 T 13-09-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 THL1_RS22010 abd7bea4c395e4a6ec831e0f08489a75 180 SMART SM00857 3 137 1.2E-52 T 13-09-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 THL1_RS12445 b32e6b30d2c35b03ee4390df56b9dff3 111 Gene3D G3DSA:1.10.10.370 42 111 8.6E-29 T 13-09-2016 THL1_RS12445 b32e6b30d2c35b03ee4390df56b9dff3 111 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 6 111 1.9E-43 T 13-09-2016 IPR007453 Sulphur transfer protein DsrC/TusE THL1_RS12445 b32e6b30d2c35b03ee4390df56b9dff3 111 Gene3D G3DSA:3.30.1420.10 1 41 7.3E-14 T 13-09-2016 THL1_RS12445 b32e6b30d2c35b03ee4390df56b9dff3 111 Pfam PF04358 DsrC like protein 6 111 6.2E-37 T 13-09-2016 IPR007453 Sulphur transfer protein DsrC/TusE THL1_RS12445 b32e6b30d2c35b03ee4390df56b9dff3 111 SUPERFAMILY SSF69721 3 111 1.28E-34 T 13-09-2016 IPR025526 DsrC-like domain THL1_RS12445 b32e6b30d2c35b03ee4390df56b9dff3 111 PANTHER PTHR37010:SF1 1 111 2.4E-51 T 13-09-2016 THL1_RS12445 b32e6b30d2c35b03ee4390df56b9dff3 111 PANTHER PTHR37010 1 111 2.4E-51 T 13-09-2016 THL1_RS12445 b32e6b30d2c35b03ee4390df56b9dff3 111 PIRSF PIRSF006223 4 111 1.6E-32 T 13-09-2016 IPR007453 Sulphur transfer protein DsrC/TusE THL1_RS13675 6ef45e5518bd26cb5933f8f710a7cd45 416 Gene3D G3DSA:3.90.1150.10 295 413 2.1E-29 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS13675 6ef45e5518bd26cb5933f8f710a7cd45 416 Pfam PF00202 Aminotransferase class-III 15 412 4.1E-104 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS13675 6ef45e5518bd26cb5933f8f710a7cd45 416 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 227 264 - T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS13675 6ef45e5518bd26cb5933f8f710a7cd45 416 PANTHER PTHR11986 15 412 9.8E-141 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS13675 6ef45e5518bd26cb5933f8f710a7cd45 416 PANTHER PTHR11986:SF17 15 412 9.8E-141 T 13-09-2016 THL1_RS13675 6ef45e5518bd26cb5933f8f710a7cd45 416 Gene3D G3DSA:3.40.640.10 50 294 8.5E-77 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS13675 6ef45e5518bd26cb5933f8f710a7cd45 416 SUPERFAMILY SSF53383 12 412 3.46E-113 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS00325 aa2e31f843757e8b948b4cb0ab6ec2a8 261 Pfam PF00950 ABC 3 transport family 2 256 5.1E-78 T 13-09-2016 IPR001626 ABC-3 GO:0005524|GO:0006810|GO:0016020|GO:0042626 THL1_RS00325 aa2e31f843757e8b948b4cb0ab6ec2a8 261 Gene3D G3DSA:1.10.3470.10 39 251 5.8E-8 T 13-09-2016 IPR029022 ABC transporter, BtuC-like THL1_RS00325 aa2e31f843757e8b948b4cb0ab6ec2a8 261 SUPERFAMILY SSF81345 3 253 7.19E-40 T 13-09-2016 IPR029022 ABC transporter, BtuC-like THL1_RS00325 aa2e31f843757e8b948b4cb0ab6ec2a8 261 PANTHER PTHR30477:SF0 3 261 1.9E-89 T 13-09-2016 THL1_RS00325 aa2e31f843757e8b948b4cb0ab6ec2a8 261 PANTHER PTHR30477 3 261 1.9E-89 T 13-09-2016 THL1_RS13240 67de3de4e06d258763cc865e62452bbc 217 PANTHER PTHR30055 12 195 1.3E-15 T 13-09-2016 THL1_RS13240 67de3de4e06d258763cc865e62452bbc 217 SUPERFAMILY SSF46689 21 92 6.48E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13240 67de3de4e06d258763cc865e62452bbc 217 Gene3D G3DSA:1.10.357.10 3 197 1.1E-24 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS13240 67de3de4e06d258763cc865e62452bbc 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 2.6E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS13240 67de3de4e06d258763cc865e62452bbc 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 2.6E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS13240 67de3de4e06d258763cc865e62452bbc 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 76 9.1E-10 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS05060 e1bddecea266e6fd40613aabd32d89e3 66 Hamap MF_00649 DNA gyrase inhibitor YacG [yacG]. 3 60 19.803 T 13-09-2016 IPR005584 DNA gyrase inhibitor YacG GO:0008270 THL1_RS05060 e1bddecea266e6fd40613aabd32d89e3 66 Pfam PF03884 Domain of unknown function (DUF329) 7 55 5.0E-26 T 13-09-2016 IPR005584 DNA gyrase inhibitor YacG GO:0008270 THL1_RS05060 e1bddecea266e6fd40613aabd32d89e3 66 SUPERFAMILY SSF57716 2 55 1.43E-21 T 13-09-2016 THL1_RS05060 e1bddecea266e6fd40613aabd32d89e3 66 PANTHER PTHR36150 2 65 3.6E-25 T 13-09-2016 THL1_RS05060 e1bddecea266e6fd40613aabd32d89e3 66 PANTHER PTHR36150:SF1 2 65 3.6E-25 T 13-09-2016 THL1_RS05060 e1bddecea266e6fd40613aabd32d89e3 66 Gene3D G3DSA:3.30.50.10 2 55 2.2E-25 T 13-09-2016 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 THL1_RS02460 c6f56281f7e08c0249577ad9fc517d19 342 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 272 333 3.0E-27 T 13-09-2016 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 THL1_RS02460 c6f56281f7e08c0249577ad9fc517d19 342 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 342 220.493 T 13-09-2016 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 THL1_RS02460 c6f56281f7e08c0249577ad9fc517d19 342 Gene3D G3DSA:1.10.8.60 275 337 9.4E-32 T 13-09-2016 THL1_RS02460 c6f56281f7e08c0249577ad9fc517d19 342 PANTHER PTHR10277 1 336 1.8E-121 T 13-09-2016 THL1_RS02460 c6f56281f7e08c0249577ad9fc517d19 342 SUPERFAMILY SSF89000 288 336 6.28E-18 T 13-09-2016 THL1_RS02460 c6f56281f7e08c0249577ad9fc517d19 342 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 4 335 1.1E-178 T 13-09-2016 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 THL1_RS02460 c6f56281f7e08c0249577ad9fc517d19 342 PANTHER PTHR10277:SF3 1 336 1.8E-121 T 13-09-2016 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 THL1_RS02460 c6f56281f7e08c0249577ad9fc517d19 342 Pfam PF00682 HMGL-like 6 262 1.7E-77 T 13-09-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 THL1_RS02460 c6f56281f7e08c0249577ad9fc517d19 342 SUPERFAMILY SSF51569 3 276 2.2E-67 T 13-09-2016 THL1_RS02460 c6f56281f7e08c0249577ad9fc517d19 342 Gene3D G3DSA:3.20.20.70 4 262 1.6E-56 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS02460 c6f56281f7e08c0249577ad9fc517d19 342 Pfam PF07836 DmpG-like communication domain 274 333 5.3E-29 T 13-09-2016 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 THL1_RS25545 f0d80fb957d8f399c7ab7a0c8b52d0c5 362 PANTHER PTHR30482 121 359 6.5E-192 T 13-09-2016 THL1_RS25545 f0d80fb957d8f399c7ab7a0c8b52d0c5 362 PANTHER PTHR30482 2 99 6.5E-192 T 13-09-2016 THL1_RS25545 f0d80fb957d8f399c7ab7a0c8b52d0c5 362 PANTHER PTHR30482:SF4 2 99 6.5E-192 T 13-09-2016 IPR017778 ABC transporter, urea, permease protein, UrtC THL1_RS25545 f0d80fb957d8f399c7ab7a0c8b52d0c5 362 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 345 8.8E-41 T 13-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 THL1_RS25545 f0d80fb957d8f399c7ab7a0c8b52d0c5 362 PANTHER PTHR30482:SF4 121 359 6.5E-192 T 13-09-2016 IPR017778 ABC transporter, urea, permease protein, UrtC THL1_RS25545 f0d80fb957d8f399c7ab7a0c8b52d0c5 362 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 47 356 3.3E-133 T 13-09-2016 IPR017778 ABC transporter, urea, permease protein, UrtC THL1_RS04825 d77149018607c527677a497514b2ed10 85 SUPERFAMILY SSF110324 2 81 1.88E-33 T 13-09-2016 THL1_RS04825 d77149018607c527677a497514b2ed10 85 Pfam PF01016 Ribosomal L27 protein 2 82 8.5E-38 T 13-09-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS04825 d77149018607c527677a497514b2ed10 85 PANTHER PTHR15893 1 85 8.8E-49 T 13-09-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS04825 d77149018607c527677a497514b2ed10 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 83 2.6E-40 T 13-09-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS04825 d77149018607c527677a497514b2ed10 85 Gene3D G3DSA:2.40.50.100 20 83 1.0E-29 T 13-09-2016 THL1_RS04825 d77149018607c527677a497514b2ed10 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 28.969 T 13-09-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS04825 d77149018607c527677a497514b2ed10 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 13-09-2016 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS04825 d77149018607c527677a497514b2ed10 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 71 7.0E-16 T 13-09-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS04825 d77149018607c527677a497514b2ed10 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 8.7E-38 T 13-09-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS04825 d77149018607c527677a497514b2ed10 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 8.7E-38 T 13-09-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS04825 d77149018607c527677a497514b2ed10 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 8.7E-38 T 13-09-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS11945 174e009e9257cbbcf7d42a5102c90f00 246 Pfam PF00535 Glycosyl transferase family 2 8 171 2.0E-26 T 13-09-2016 IPR001173 Glycosyltransferase 2-like THL1_RS11945 174e009e9257cbbcf7d42a5102c90f00 246 Gene3D G3DSA:3.90.550.10 6 178 1.4E-22 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS11945 174e009e9257cbbcf7d42a5102c90f00 246 PANTHER PTHR10859 3 239 5.7E-67 T 13-09-2016 THL1_RS11945 174e009e9257cbbcf7d42a5102c90f00 246 PANTHER PTHR10859:SF49 3 239 5.7E-67 T 13-09-2016 THL1_RS11945 174e009e9257cbbcf7d42a5102c90f00 246 SUPERFAMILY SSF53448 2 232 3.89E-38 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS19150 c26db9ccdc5006e682da3cd2212d04a5 439 Pfam PF07690 Major Facilitator Superfamily 240 421 6.3E-14 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS19150 c26db9ccdc5006e682da3cd2212d04a5 439 Gene3D G3DSA:1.20.1250.20 231 417 2.8E-24 T 13-09-2016 THL1_RS19150 c26db9ccdc5006e682da3cd2212d04a5 439 Gene3D G3DSA:1.20.1250.20 12 211 3.4E-21 T 13-09-2016 THL1_RS19150 c26db9ccdc5006e682da3cd2212d04a5 439 PANTHER PTHR23508 2 436 5.4E-128 T 13-09-2016 THL1_RS19150 c26db9ccdc5006e682da3cd2212d04a5 439 Pfam PF00083 Sugar (and other) transporter 20 211 8.5E-16 T 13-09-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 THL1_RS19150 c26db9ccdc5006e682da3cd2212d04a5 439 ProSitePatterns PS00217 Sugar transport proteins signature 2. 333 358 - T 13-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 THL1_RS19150 c26db9ccdc5006e682da3cd2212d04a5 439 PANTHER PTHR23508:SF1 2 436 5.4E-128 T 13-09-2016 THL1_RS19150 c26db9ccdc5006e682da3cd2212d04a5 439 ProSitePatterns PS00217 Sugar transport proteins signature 2. 124 149 - T 13-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 THL1_RS19150 c26db9ccdc5006e682da3cd2212d04a5 439 SUPERFAMILY SSF103473 8 424 9.02E-65 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS00870 1ad21011c93c9c505e9301717bd9ab5b 112 PANTHER PTHR24220:SF10 14 111 6.1E-33 T 13-09-2016 THL1_RS00870 1ad21011c93c9c505e9301717bd9ab5b 112 Gene3D G3DSA:3.40.50.300 11 111 3.5E-24 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00870 1ad21011c93c9c505e9301717bd9ab5b 112 Pfam PF00005 ABC transporter 33 105 1.2E-12 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS00870 1ad21011c93c9c505e9301717bd9ab5b 112 SUPERFAMILY SSF52540 13 111 4.85E-23 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00870 1ad21011c93c9c505e9301717bd9ab5b 112 PANTHER PTHR24220 14 111 6.1E-33 T 13-09-2016 THL1_RS16120 299b9b3c03177b4d80374646fdd124a1 275 SUPERFAMILY SSF47090 3 65 1.31E-18 T 13-09-2016 IPR002477 Peptidoglycan binding-like THL1_RS16120 299b9b3c03177b4d80374646fdd124a1 275 Gene3D G3DSA:1.10.101.10 2 65 1.7E-21 T 13-09-2016 IPR002477 Peptidoglycan binding-like THL1_RS16120 299b9b3c03177b4d80374646fdd124a1 275 Pfam PF01471 Putative peptidoglycan binding domain 9 64 2.1E-16 T 13-09-2016 IPR002477 Peptidoglycan binding-like THL1_RS16120 299b9b3c03177b4d80374646fdd124a1 275 Pfam PF11860 Protein of unknown function (DUF3380) 88 269 6.2E-64 T 13-09-2016 IPR024408 Domain of unknown function DUF3380 THL1_RS19330 ac8670762505f5ae33bc34bb70ff55ed 277 PANTHER PTHR34990 8 263 1.8E-143 T 13-09-2016 THL1_RS19330 ac8670762505f5ae33bc34bb70ff55ed 277 PANTHER PTHR34990:SF2 8 263 1.8E-143 T 13-09-2016 THL1_RS19330 ac8670762505f5ae33bc34bb70ff55ed 277 SUPERFAMILY SSF56300 197 258 1.52E-33 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS19330 ac8670762505f5ae33bc34bb70ff55ed 277 SUPERFAMILY SSF56300 20 141 1.52E-33 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS19330 ac8670762505f5ae33bc34bb70ff55ed 277 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 22 236 2.6E-13 T 13-09-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type THL1_RS19330 ac8670762505f5ae33bc34bb70ff55ed 277 Gene3D G3DSA:3.60.21.10 21 155 3.5E-33 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS19330 ac8670762505f5ae33bc34bb70ff55ed 277 Gene3D G3DSA:3.60.21.10 204 256 3.5E-33 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS14245 ab40e34eb0ec819d04a42f437bbfddfd 594 Gene3D G3DSA:2.140.10.10 42 592 9.3E-153 T 13-09-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain THL1_RS14245 ab40e34eb0ec819d04a42f437bbfddfd 594 Pfam PF13360 PQQ-like domain 74 229 3.3E-16 T 13-09-2016 IPR002372 Pyrrolo-quinoline quinone repeat THL1_RS14245 ab40e34eb0ec819d04a42f437bbfddfd 594 Pfam PF13360 PQQ-like domain 472 539 9.3E-8 T 13-09-2016 IPR002372 Pyrrolo-quinoline quinone repeat THL1_RS14245 ab40e34eb0ec819d04a42f437bbfddfd 594 PANTHER PTHR32303 7 224 2.7E-108 T 13-09-2016 THL1_RS14245 ab40e34eb0ec819d04a42f437bbfddfd 594 PANTHER PTHR32303 403 571 2.7E-108 T 13-09-2016 THL1_RS14245 ab40e34eb0ec819d04a42f437bbfddfd 594 SMART SM00564 140 171 1.8E-4 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS14245 ab40e34eb0ec819d04a42f437bbfddfd 594 SMART SM00564 185 222 1.0 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS14245 ab40e34eb0ec819d04a42f437bbfddfd 594 SMART SM00564 447 489 1.2 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS14245 ab40e34eb0ec819d04a42f437bbfddfd 594 SMART SM00564 499 530 0.11 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS14245 ab40e34eb0ec819d04a42f437bbfddfd 594 SMART SM00564 289 316 93.0 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS14245 ab40e34eb0ec819d04a42f437bbfddfd 594 SMART SM00564 90 122 3.0E-5 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS14245 ab40e34eb0ec819d04a42f437bbfddfd 594 PANTHER PTHR32303 244 365 2.7E-108 T 13-09-2016 THL1_RS14245 ab40e34eb0ec819d04a42f437bbfddfd 594 TIGRFAM TIGR03075 PQQ_enz_alc_DH: PQQ-dependent dehydrogenase, methanol/ethanol family 28 558 2.1E-238 T 13-09-2016 IPR017512 PQQ-dependent dehydrogenase, methanol/ethanol family GO:0005509|GO:0016020|GO:0016614|GO:0055114 THL1_RS14245 ab40e34eb0ec819d04a42f437bbfddfd 594 PANTHER PTHR32303:SF2 7 224 2.7E-108 T 13-09-2016 THL1_RS14245 ab40e34eb0ec819d04a42f437bbfddfd 594 PANTHER PTHR32303:SF2 403 571 2.7E-108 T 13-09-2016 THL1_RS14245 ab40e34eb0ec819d04a42f437bbfddfd 594 SUPERFAMILY SSF50998 39 581 1.19E-159 T 13-09-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THL1_RS14245 ab40e34eb0ec819d04a42f437bbfddfd 594 PANTHER PTHR32303:SF2 244 365 2.7E-108 T 13-09-2016 THL1_RS02115 b1fcf641858d0a324eecc5f3467abc0a 644 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 499 642 2.1E-47 T 13-09-2016 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding THL1_RS02115 b1fcf641858d0a324eecc5f3467abc0a 644 Gene3D G3DSA:3.10.580.10 177 294 1.2E-30 T 13-09-2016 THL1_RS02115 b1fcf641858d0a324eecc5f3467abc0a 644 SUPERFAMILY SSF54631 179 295 5.05E-28 T 13-09-2016 THL1_RS02115 b1fcf641858d0a324eecc5f3467abc0a 644 PANTHER PTHR11911 174 294 3.8E-26 T 13-09-2016 THL1_RS02115 b1fcf641858d0a324eecc5f3467abc0a 644 Pfam PF00027 Cyclic nucleotide-binding domain 50 137 4.6E-9 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS02115 b1fcf641858d0a324eecc5f3467abc0a 644 SMART SM00116 186 234 4.3E-10 T 13-09-2016 IPR000644 CBS domain THL1_RS02115 b1fcf641858d0a324eecc5f3467abc0a 644 SMART SM00116 251 298 0.08 T 13-09-2016 IPR000644 CBS domain THL1_RS02115 b1fcf641858d0a324eecc5f3467abc0a 644 Pfam PF03445 Putative nucleotidyltransferase DUF294 323 462 2.0E-45 T 13-09-2016 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 THL1_RS02115 b1fcf641858d0a324eecc5f3467abc0a 644 Pfam PF00571 CBS domain 245 296 4.6E-8 T 13-09-2016 IPR000644 CBS domain THL1_RS02115 b1fcf641858d0a324eecc5f3467abc0a 644 Pfam PF00571 CBS domain 180 234 7.4E-10 T 13-09-2016 IPR000644 CBS domain THL1_RS02115 b1fcf641858d0a324eecc5f3467abc0a 644 SUPERFAMILY SSF51206 23 161 1.15E-16 T 13-09-2016 IPR018490 Cyclic nucleotide-binding-like THL1_RS02115 b1fcf641858d0a324eecc5f3467abc0a 644 Gene3D G3DSA:2.60.120.10 22 162 7.3E-13 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS17500 494976658e6beca0bf90e54148062cfc 294 PANTHER PTHR11795:SF379 10 294 5.0E-116 T 13-09-2016 THL1_RS17500 494976658e6beca0bf90e54148062cfc 294 Pfam PF02653 Branched-chain amino acid transport system / permease component 16 282 2.0E-39 T 13-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 THL1_RS17500 494976658e6beca0bf90e54148062cfc 294 PANTHER PTHR11795 10 294 5.0E-116 T 13-09-2016 THL1_RS13755 da22d3f21936414bcb2941f500362578 390 Pfam PF07690 Major Facilitator Superfamily 27 190 1.8E-10 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS13755 da22d3f21936414bcb2941f500362578 390 SUPERFAMILY SSF103473 6 380 3.66E-34 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS13755 da22d3f21936414bcb2941f500362578 390 Gene3D G3DSA:1.20.1250.20 205 371 3.1E-9 T 13-09-2016 THL1_RS13755 da22d3f21936414bcb2941f500362578 390 Gene3D G3DSA:1.20.1250.20 9 188 1.8E-12 T 13-09-2016 THL1_RS04620 9d11af1908630969054a637c312f4ac6 188 Pfam PF01965 DJ-1/PfpI family 9 171 4.8E-48 T 13-09-2016 IPR002818 DJ-1/PfpI THL1_RS04620 9d11af1908630969054a637c312f4ac6 188 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 9 183 1.4E-58 T 13-09-2016 IPR006287 DJ-1 THL1_RS04620 9d11af1908630969054a637c312f4ac6 188 Gene3D G3DSA:3.40.50.880 8 187 1.6E-57 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS04620 9d11af1908630969054a637c312f4ac6 188 PANTHER PTHR11019 8 172 7.8E-57 T 13-09-2016 THL1_RS04620 9d11af1908630969054a637c312f4ac6 188 PANTHER PTHR11019:SF100 8 172 7.8E-57 T 13-09-2016 THL1_RS04620 9d11af1908630969054a637c312f4ac6 188 SUPERFAMILY SSF52317 9 187 1.68E-50 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS21595 a57eeeaeb90074e4d1df22d251157ab6 156 Gene3D G3DSA:1.20.1260.10 1 156 1.9E-67 T 13-09-2016 IPR012347 Ferritin-related THL1_RS21595 a57eeeaeb90074e4d1df22d251157ab6 156 PRINTS PR00601 Bacterioferritin signature 86 106 5.1E-74 T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS21595 a57eeeaeb90074e4d1df22d251157ab6 156 PRINTS PR00601 Bacterioferritin signature 65 85 5.1E-74 T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS21595 a57eeeaeb90074e4d1df22d251157ab6 156 PRINTS PR00601 Bacterioferritin signature 128 149 5.1E-74 T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS21595 a57eeeaeb90074e4d1df22d251157ab6 156 PRINTS PR00601 Bacterioferritin signature 3 22 5.1E-74 T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS21595 a57eeeaeb90074e4d1df22d251157ab6 156 PRINTS PR00601 Bacterioferritin signature 44 64 5.1E-74 T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS21595 a57eeeaeb90074e4d1df22d251157ab6 156 PRINTS PR00601 Bacterioferritin signature 23 43 5.1E-74 T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS21595 a57eeeaeb90074e4d1df22d251157ab6 156 PRINTS PR00601 Bacterioferritin signature 107 127 5.1E-74 T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS21595 a57eeeaeb90074e4d1df22d251157ab6 156 PANTHER PTHR30295 1 156 2.6E-62 T 13-09-2016 THL1_RS21595 a57eeeaeb90074e4d1df22d251157ab6 156 Pfam PF00210 Ferritin-like domain 8 144 1.1E-40 T 13-09-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 THL1_RS21595 a57eeeaeb90074e4d1df22d251157ab6 156 PIRSF PIRSF002560 1 156 4.2E-75 T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS21595 a57eeeaeb90074e4d1df22d251157ab6 156 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS21595 a57eeeaeb90074e4d1df22d251157ab6 156 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 4.7E-78 T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS21595 a57eeeaeb90074e4d1df22d251157ab6 156 SUPERFAMILY SSF47240 1 154 5.08E-57 T 13-09-2016 IPR009078 Ferritin-like superfamily THL1_RS21595 a57eeeaeb90074e4d1df22d251157ab6 156 PANTHER PTHR30295:SF9 1 156 2.6E-62 T 13-09-2016 THL1_RS17345 093903813f77c9b04f7dc5614d6db401 443 Pfam PF07805 HipA-like N-terminal domain 140 218 5.9E-9 T 13-09-2016 IPR012894 HipA, N-terminal subdomain 2 THL1_RS17345 093903813f77c9b04f7dc5614d6db401 443 Pfam PF07804 HipA-like C-terminal domain 226 365 1.3E-21 T 13-09-2016 IPR012893 HipA-like, C-terminal THL1_RS17345 093903813f77c9b04f7dc5614d6db401 443 Pfam PF13657 HipA N-terminal domain 3 99 2.0E-12 T 13-09-2016 IPR017508 HipA, N-terminal subdomain 1 THL1_RS17345 093903813f77c9b04f7dc5614d6db401 443 PANTHER PTHR37419 21 320 5.2E-12 T 13-09-2016 THL1_RS22895 d8ba86a1fcc257d81c04c1d172de4db9 334 SMART SM00448 1 116 4.9E-9 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS22895 d8ba86a1fcc257d81c04c1d172de4db9 334 Pfam PF00072 Response regulator receiver domain 4 102 1.1E-14 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS22895 d8ba86a1fcc257d81c04c1d172de4db9 334 Pfam PF01339 CheB methylesterase 153 329 2.7E-58 T 13-09-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS22895 d8ba86a1fcc257d81c04c1d172de4db9 334 PANTHER PTHR24421:SF16 1 329 3.3E-107 T 13-09-2016 THL1_RS22895 d8ba86a1fcc257d81c04c1d172de4db9 334 Gene3D G3DSA:3.40.50.2300 1 105 1.2E-20 T 13-09-2016 THL1_RS22895 d8ba86a1fcc257d81c04c1d172de4db9 334 SUPERFAMILY SSF52738 150 332 2.35E-60 T 13-09-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS22895 d8ba86a1fcc257d81c04c1d172de4db9 334 PANTHER PTHR24421 1 329 3.3E-107 T 13-09-2016 THL1_RS22895 d8ba86a1fcc257d81c04c1d172de4db9 334 Gene3D G3DSA:3.40.50.180 147 332 6.4E-69 T 13-09-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS22895 d8ba86a1fcc257d81c04c1d172de4db9 334 SUPERFAMILY SSF52172 1 103 1.71E-19 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS22895 d8ba86a1fcc257d81c04c1d172de4db9 334 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 1 334 31.768 T 13-09-2016 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS22895 d8ba86a1fcc257d81c04c1d172de4db9 334 PIRSF PIRSF000876 1 334 9.3E-97 T 13-09-2016 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS26845 2eaee7bfc8bda294d759b79117c71975 229 PANTHER PTHR30450:SF7 1 229 1.3E-127 T 13-09-2016 THL1_RS26845 2eaee7bfc8bda294d759b79117c71975 229 SUPERFAMILY SSF161098 11 207 3.4E-42 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS26845 2eaee7bfc8bda294d759b79117c71975 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 116 4.9E-23 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS26845 2eaee7bfc8bda294d759b79117c71975 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 222 1.8E-19 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS26845 2eaee7bfc8bda294d759b79117c71975 229 Gene3D G3DSA:1.10.3720.10 9 222 2.4E-45 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS26845 2eaee7bfc8bda294d759b79117c71975 229 PANTHER PTHR30450 1 229 1.3E-127 T 13-09-2016 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 PRINTS PR00046 Major sigma-70 factor signature 576 591 6.5E-31 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 PRINTS PR00046 Major sigma-70 factor signature 591 602 6.5E-31 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 PRINTS PR00046 Major sigma-70 factor signature 407 420 6.5E-31 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 PRINTS PR00046 Major sigma-70 factor signature 431 439 6.5E-31 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 PRINTS PR00046 Major sigma-70 factor signature 555 567 6.5E-31 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 SUPERFAMILY SSF88659 456 529 1.18E-20 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 576 602 - T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 Pfam PF00140 Sigma-70 factor, region 1.2 98 128 3.9E-13 T 13-09-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 Gene3D G3DSA:1.10.10.10 456 507 1.9E-27 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02530 aba7695785eed5445743438a5893e46e 617 Pfam PF04542 Sigma-70 region 2 383 452 1.7E-21 T 13-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 407 420 - T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 Gene3D G3DSA:1.10.601.10 112 452 8.2E-135 T 13-09-2016 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 PANTHER PTHR30603 7 152 1.4E-252 T 13-09-2016 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 Pfam PF04545 Sigma-70, region 4 551 604 9.0E-19 T 13-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 PANTHER PTHR30603:SF0 7 152 1.4E-252 T 13-09-2016 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 Pfam PF04546 Sigma-70, non-essential region 139 352 1.9E-64 T 13-09-2016 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 Gene3D G3DSA:1.10.10.10 546 616 9.4E-33 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02530 aba7695785eed5445743438a5893e46e 617 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 6 616 46.934 T 13-09-2016 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 Pfam PF03979 Sigma-70 factor, region 1.1 6 83 3.8E-30 T 13-09-2016 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 SUPERFAMILY SSF88659 513 615 7.63E-27 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 PANTHER PTHR30603 330 616 1.4E-252 T 13-09-2016 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 379 615 8.4E-122 T 13-09-2016 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 379 604 8.8E-37 T 13-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 PANTHER PTHR30603:SF0 330 616 1.4E-252 T 13-09-2016 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 Pfam PF04539 Sigma-70 region 3 462 537 1.5E-29 T 13-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS02530 aba7695785eed5445743438a5893e46e 617 SUPERFAMILY SSF88946 115 450 3.92E-104 T 13-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS22530 caca771a4882149d583316a3958eee9c 236 Gene3D G3DSA:3.90.550.10 9 231 3.4E-66 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS22530 caca771a4882149d583316a3958eee9c 236 PANTHER PTHR32125 10 227 7.3E-71 T 13-09-2016 THL1_RS22530 caca771a4882149d583316a3958eee9c 236 PANTHER PTHR32125:SF4 10 227 7.3E-71 T 13-09-2016 THL1_RS22530 caca771a4882149d583316a3958eee9c 236 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 108 115 - T 13-09-2016 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS22530 caca771a4882149d583316a3958eee9c 236 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 11 225 8.7E-65 T 13-09-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS22530 caca771a4882149d583316a3958eee9c 236 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 8 235 29.319 T 13-09-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS22530 caca771a4882149d583316a3958eee9c 236 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 10 228 1.1E-70 T 13-09-2016 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS22530 caca771a4882149d583316a3958eee9c 236 SUPERFAMILY SSF53448 10 232 1.04E-53 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS07390 2ee309e9439fa452d591b62cc985d894 282 SUPERFAMILY SSF88713 5 279 1.68E-62 T 13-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THL1_RS07390 2ee309e9439fa452d591b62cc985d894 282 Pfam PF01522 Polysaccharide deacetylase 26 153 1.0E-18 T 13-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 THL1_RS07390 2ee309e9439fa452d591b62cc985d894 282 PANTHER PTHR10587 48 164 3.5E-24 T 13-09-2016 THL1_RS07390 2ee309e9439fa452d591b62cc985d894 282 Gene3D G3DSA:3.20.20.370 5 279 6.7E-70 T 13-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 THL1_RS05265 8da50ce5af3ef39faee41c11d58fe551 313 PANTHER PTHR31752 93 309 5.1E-50 T 13-09-2016 THL1_RS05265 8da50ce5af3ef39faee41c11d58fe551 313 PANTHER PTHR31752:SF13 93 309 5.1E-50 T 13-09-2016 THL1_RS05265 8da50ce5af3ef39faee41c11d58fe551 313 Pfam PF03547 Membrane transport protein 169 301 3.8E-10 T 13-09-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 THL1_RS05265 8da50ce5af3ef39faee41c11d58fe551 313 Pfam PF03547 Membrane transport protein 13 135 1.0E-9 T 13-09-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 THL1_RS23175 3f771590b4e6cd9a162b55beadd8e8ab 375 SMART SM00267 200 369 1.4E-58 T 13-09-2016 IPR000160 GGDEF domain THL1_RS23175 3f771590b4e6cd9a162b55beadd8e8ab 375 Pfam PF00990 Diguanylate cyclase, GGDEF domain 212 365 1.7E-43 T 13-09-2016 IPR000160 GGDEF domain THL1_RS23175 3f771590b4e6cd9a162b55beadd8e8ab 375 PANTHER PTHR10799:SF710 96 365 5.0E-24 T 13-09-2016 THL1_RS23175 3f771590b4e6cd9a162b55beadd8e8ab 375 SUPERFAMILY SSF55073 216 366 3.53E-46 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS23175 3f771590b4e6cd9a162b55beadd8e8ab 375 Gene3D G3DSA:3.30.70.270 213 367 2.4E-49 T 13-09-2016 THL1_RS23175 3f771590b4e6cd9a162b55beadd8e8ab 375 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 207 367 2.5E-40 T 13-09-2016 IPR000160 GGDEF domain THL1_RS23175 3f771590b4e6cd9a162b55beadd8e8ab 375 PANTHER PTHR10799 96 365 5.0E-24 T 13-09-2016 THL1_RS08325 eef237c28fcafbdde32c4bf6d7d56ed5 318 Gene3D G3DSA:2.20.150.10 11 37 5.8E-5 T 13-09-2016 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395|UniPathway: UPA00704 THL1_RS08325 eef237c28fcafbdde32c4bf6d7d56ed5 318 SUPERFAMILY SSF53613 4 290 2.18E-64 T 13-09-2016 IPR029056 Ribokinase-like THL1_RS08325 eef237c28fcafbdde32c4bf6d7d56ed5 318 PIRSF PIRSF000535 1 310 1.1E-84 T 13-09-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 THL1_RS08325 eef237c28fcafbdde32c4bf6d7d56ed5 318 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 4 307 2.0E-99 T 13-09-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 THL1_RS08325 eef237c28fcafbdde32c4bf6d7d56ed5 318 Pfam PF00294 pfkB family carbohydrate kinase 15 291 1.4E-43 T 13-09-2016 IPR011611 Carbohydrate kinase PfkB THL1_RS08325 eef237c28fcafbdde32c4bf6d7d56ed5 318 PANTHER PTHR10584 3 302 2.9E-103 T 13-09-2016 THL1_RS08325 eef237c28fcafbdde32c4bf6d7d56ed5 318 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 38 62 - T 13-09-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 THL1_RS08325 eef237c28fcafbdde32c4bf6d7d56ed5 318 Gene3D G3DSA:3.40.1190.20 38 308 1.5E-75 T 13-09-2016 IPR029056 Ribokinase-like THL1_RS08325 eef237c28fcafbdde32c4bf6d7d56ed5 318 PANTHER PTHR10584:SF170 3 302 2.9E-103 T 13-09-2016 THL1_RS08325 eef237c28fcafbdde32c4bf6d7d56ed5 318 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 4 307 4.6E-100 T 13-09-2016 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 THL1_RS08325 eef237c28fcafbdde32c4bf6d7d56ed5 318 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 248 261 - T 13-09-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 THL1_RS19455 16dd5c5a598fe17a7466379b5bd221e5 145 SUPERFAMILY SSF52821 7 130 5.11E-21 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS19455 16dd5c5a598fe17a7466379b5bd221e5 145 Gene3D G3DSA:3.40.250.10 18 128 2.0E-16 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS19455 16dd5c5a598fe17a7466379b5bd221e5 145 Pfam PF00581 Rhodanese-like domain 41 124 3.0E-10 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS17060 735893f2fe2e7a93b43afca64d233058 356 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 107 2.4E-8 T 13-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 THL1_RS17060 735893f2fe2e7a93b43afca64d233058 356 SUPERFAMILY SSF51735 1 144 2.91E-12 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS17060 735893f2fe2e7a93b43afca64d233058 356 Gene3D G3DSA:3.40.50.720 1 174 2.0E-14 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS21650 6ad9b0e224065b3f370f7bdba7b35a93 504 PANTHER PTHR11985:SF1 8 492 5.4E-187 T 13-09-2016 THL1_RS21650 6ad9b0e224065b3f370f7bdba7b35a93 504 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 388 489 1.8E-12 T 13-09-2016 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 THL1_RS21650 6ad9b0e224065b3f370f7bdba7b35a93 504 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 12 24 9.8E-30 T 13-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 THL1_RS21650 6ad9b0e224065b3f370f7bdba7b35a93 504 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 86 98 9.8E-30 T 13-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 THL1_RS21650 6ad9b0e224065b3f370f7bdba7b35a93 504 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 354 366 9.8E-30 T 13-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 THL1_RS21650 6ad9b0e224065b3f370f7bdba7b35a93 504 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 25 35 9.8E-30 T 13-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 THL1_RS21650 6ad9b0e224065b3f370f7bdba7b35a93 504 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 41 53 9.8E-30 T 13-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 THL1_RS21650 6ad9b0e224065b3f370f7bdba7b35a93 504 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 320 326 9.8E-30 T 13-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 THL1_RS21650 6ad9b0e224065b3f370f7bdba7b35a93 504 Pfam PF01266 FAD dependent oxidoreductase 13 365 1.0E-47 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS21650 6ad9b0e224065b3f370f7bdba7b35a93 504 SUPERFAMILY SSF51905 12 329 3.08E-34 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21650 6ad9b0e224065b3f370f7bdba7b35a93 504 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 359 369 - T 13-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 THL1_RS21650 6ad9b0e224065b3f370f7bdba7b35a93 504 Gene3D G3DSA:3.50.50.60 12 263 9.0E-36 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21650 6ad9b0e224065b3f370f7bdba7b35a93 504 PANTHER PTHR11985 8 492 5.4E-187 T 13-09-2016 THL1_RS21650 6ad9b0e224065b3f370f7bdba7b35a93 504 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 17 34 - T 13-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 THL1_RS06850 7feb64bf6c7b065ae3df465115527b83 122 Pfam PF10861 Protein of Unknown function (DUF2784) 4 110 4.7E-41 T 13-09-2016 IPR021218 Protein of unknown function DUF2784 THL1_RS08185 5656c6e5f2908f8927eecc46919cef90 382 Gene3D G3DSA:3.40.710.10 4 377 4.2E-83 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS08185 5656c6e5f2908f8927eecc46919cef90 382 PANTHER PTHR10566:SF94 91 257 9.6E-41 T 13-09-2016 THL1_RS08185 5656c6e5f2908f8927eecc46919cef90 382 SUPERFAMILY SSF56601 10 376 4.06E-78 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS08185 5656c6e5f2908f8927eecc46919cef90 382 PANTHER PTHR10566 91 257 9.6E-41 T 13-09-2016 THL1_RS08185 5656c6e5f2908f8927eecc46919cef90 382 Pfam PF00144 Beta-lactamase 18 371 8.1E-76 T 13-09-2016 IPR001466 Beta-lactamase-related THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 Pfam PF00873 AcrB/AcrD/AcrF family 6 1035 5.5E-234 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 SUPERFAMILY SSF82714 723 807 4.71E-17 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 SUPERFAMILY SSF82693 271 328 1.23E-21 T 13-09-2016 THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 SUPERFAMILY SSF82693 137 184 1.23E-21 T 13-09-2016 THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 1.1E-22 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 1.1E-22 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 1.1E-22 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 PRINTS PR00702 Acriflavin resistance protein family signature 552 569 1.1E-22 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 1.1E-22 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 SUPERFAMILY SSF82714 185 269 2.75E-16 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 SUPERFAMILY SSF82693 46 127 6.28E-20 T 13-09-2016 THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 SUPERFAMILY SSF82866 294 506 1.96E-38 T 13-09-2016 THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 Gene3D G3DSA:3.30.70.1430 46 142 1.2E-23 T 13-09-2016 THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1039 0.0 T 13-09-2016 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 SUPERFAMILY SSF82866 806 1039 1.11E-45 T 13-09-2016 THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 Gene3D G3DSA:3.30.2090.10 723 811 1.3E-17 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 PANTHER PTHR32063:SF19 2 1040 0.0 T 13-09-2016 THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 PANTHER PTHR32063 2 1040 0.0 T 13-09-2016 THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 Gene3D G3DSA:3.30.2090.10 185 269 2.6E-15 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 Gene3D G3DSA:1.10.3850.10 276 507 5.2E-65 T 13-09-2016 THL1_RS13150 d4644e8aee07099d3f70bee9f6d007e4 1052 Gene3D G3DSA:1.10.3850.10 815 1038 3.4E-50 T 13-09-2016 THL1_RS19345 51a894b04f53e110f41447421db13e04 294 SUPERFAMILY SSF103481 186 282 7.59E-18 T 13-09-2016 THL1_RS19345 51a894b04f53e110f41447421db13e04 294 SUPERFAMILY SSF103481 43 137 1.2E-10 T 13-09-2016 THL1_RS19345 51a894b04f53e110f41447421db13e04 294 Pfam PF00892 EamA-like transporter family 7 136 6.1E-13 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS19345 51a894b04f53e110f41447421db13e04 294 Pfam PF00892 EamA-like transporter family 149 278 5.5E-19 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS19345 51a894b04f53e110f41447421db13e04 294 PANTHER PTHR22911 1 288 4.0E-46 T 13-09-2016 THL1_RS10090 8ade291dbbca3b3630976ba2fc949e75 284 Pfam PF01416 tRNA pseudouridine synthase 159 261 3.5E-28 T 13-09-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS10090 8ade291dbbca3b3630976ba2fc949e75 284 Pfam PF01416 tRNA pseudouridine synthase 23 119 1.4E-5 T 13-09-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS10090 8ade291dbbca3b3630976ba2fc949e75 284 SUPERFAMILY SSF55120 15 275 1.08E-85 T 13-09-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS10090 8ade291dbbca3b3630976ba2fc949e75 284 PANTHER PTHR11142 15 276 7.7E-92 T 13-09-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS10090 8ade291dbbca3b3630976ba2fc949e75 284 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 16 260 32.97 T 13-09-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS10090 8ade291dbbca3b3630976ba2fc949e75 284 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 16 255 6.0E-63 T 13-09-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS10090 8ade291dbbca3b3630976ba2fc949e75 284 Gene3D G3DSA:3.30.70.660 123 259 4.1E-46 T 13-09-2016 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS10090 8ade291dbbca3b3630976ba2fc949e75 284 Gene3D G3DSA:3.30.70.580 16 121 2.8E-32 T 13-09-2016 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS10090 8ade291dbbca3b3630976ba2fc949e75 284 PIRSF PIRSF001430 15 276 4.0E-71 T 13-09-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS07885 20737b2c2ff39c7f99f4e73f4e146dec 457 PANTHER PTHR10314:SF1 53 329 1.9E-80 T 13-09-2016 THL1_RS07885 20737b2c2ff39c7f99f4e73f4e146dec 457 Gene3D G3DSA:3.40.50.1100 203 419 2.2E-62 T 13-09-2016 THL1_RS07885 20737b2c2ff39c7f99f4e73f4e146dec 457 PANTHER PTHR10314 360 408 1.9E-80 T 13-09-2016 THL1_RS07885 20737b2c2ff39c7f99f4e73f4e146dec 457 PANTHER PTHR10314 25 36 1.9E-80 T 13-09-2016 THL1_RS07885 20737b2c2ff39c7f99f4e73f4e146dec 457 Gene3D G3DSA:3.40.50.1100 132 202 1.3E-7 T 13-09-2016 THL1_RS07885 20737b2c2ff39c7f99f4e73f4e146dec 457 PANTHER PTHR10314 53 329 1.9E-80 T 13-09-2016 THL1_RS07885 20737b2c2ff39c7f99f4e73f4e146dec 457 TIGRFAM TIGR00260 thrC: threonine synthase 69 397 4.0E-52 T 13-09-2016 IPR004450 Threonine synthase-like THL1_RS07885 20737b2c2ff39c7f99f4e73f4e146dec 457 PANTHER PTHR10314:SF1 360 408 1.9E-80 T 13-09-2016 THL1_RS07885 20737b2c2ff39c7f99f4e73f4e146dec 457 PANTHER PTHR10314:SF1 25 36 1.9E-80 T 13-09-2016 THL1_RS07885 20737b2c2ff39c7f99f4e73f4e146dec 457 Gene3D G3DSA:3.90.1380.10 1 85 2.9E-24 T 13-09-2016 IPR029144 Threonine synthase, N-terminal THL1_RS07885 20737b2c2ff39c7f99f4e73f4e146dec 457 Pfam PF14821 Threonine synthase N terminus 2 80 8.6E-24 T 13-09-2016 IPR029144 Threonine synthase, N-terminal THL1_RS07885 20737b2c2ff39c7f99f4e73f4e146dec 457 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 93 397 1.7E-21 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS07885 20737b2c2ff39c7f99f4e73f4e146dec 457 SUPERFAMILY SSF53686 1 433 7.92E-117 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS00555 cfc667ce3e2aa57f6255167f981254e8 407 PANTHER PTHR24023:SF593 61 394 5.7E-38 T 13-09-2016 THL1_RS00555 cfc667ce3e2aa57f6255167f981254e8 407 Pfam PF02515 CoA-transferase family III 5 383 1.1E-134 T 13-09-2016 IPR003673 CoA-transferase family III GO:0003824 THL1_RS00555 cfc667ce3e2aa57f6255167f981254e8 407 Gene3D G3DSA:3.40.50.10540 316 407 3.3E-121 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS00555 cfc667ce3e2aa57f6255167f981254e8 407 Gene3D G3DSA:3.40.50.10540 2 227 3.3E-121 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS00555 cfc667ce3e2aa57f6255167f981254e8 407 Gene3D G3DSA:3.30.1540.10 233 315 8.5E-38 T 13-09-2016 THL1_RS00555 cfc667ce3e2aa57f6255167f981254e8 407 PANTHER PTHR24023 8 37 5.7E-38 T 13-09-2016 THL1_RS00555 cfc667ce3e2aa57f6255167f981254e8 407 PANTHER PTHR24023 61 394 5.7E-38 T 13-09-2016 THL1_RS00555 cfc667ce3e2aa57f6255167f981254e8 407 SUPERFAMILY SSF89796 3 407 3.53E-145 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS00555 cfc667ce3e2aa57f6255167f981254e8 407 PANTHER PTHR24023:SF593 8 37 5.7E-38 T 13-09-2016 THL1_RS00240 c2a2b8a31fddbcd474bb9de73b7696d7 235 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 55 62 - T 13-09-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS00240 c2a2b8a31fddbcd474bb9de73b7696d7 235 PANTHER PTHR11002:SF13 10 224 1.0E-86 T 13-09-2016 THL1_RS00240 c2a2b8a31fddbcd474bb9de73b7696d7 235 SMART SM00947 43 209 1.8E-64 T 13-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS00240 c2a2b8a31fddbcd474bb9de73b7696d7 235 PANTHER PTHR11002 10 224 1.0E-86 T 13-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS00240 c2a2b8a31fddbcd474bb9de73b7696d7 235 Gene3D G3DSA:3.40.1050.10 4 217 2.2E-74 T 13-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS00240 c2a2b8a31fddbcd474bb9de73b7696d7 235 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 98 118 - T 13-09-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS00240 c2a2b8a31fddbcd474bb9de73b7696d7 235 SUPERFAMILY SSF53056 11 218 3.79E-68 T 13-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS00240 c2a2b8a31fddbcd474bb9de73b7696d7 235 Pfam PF00484 Carbonic anhydrase 50 203 3.1E-50 T 13-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS07695 09fdb43dbc7cf87b4fe4c3a1e4f6bde5 249 PANTHER PTHR24220:SF358 6 248 1.9E-91 T 13-09-2016 THL1_RS07695 09fdb43dbc7cf87b4fe4c3a1e4f6bde5 249 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 245 3.1E-6 T 13-09-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal THL1_RS07695 09fdb43dbc7cf87b4fe4c3a1e4f6bde5 249 SUPERFAMILY SSF52540 5 246 2.22E-57 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07695 09fdb43dbc7cf87b4fe4c3a1e4f6bde5 249 Pfam PF00005 ABC transporter 22 176 9.3E-29 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS07695 09fdb43dbc7cf87b4fe4c3a1e4f6bde5 249 Gene3D G3DSA:3.40.50.300 3 244 1.7E-60 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07695 09fdb43dbc7cf87b4fe4c3a1e4f6bde5 249 PANTHER PTHR24220 6 248 1.9E-91 T 13-09-2016 THL1_RS07695 09fdb43dbc7cf87b4fe4c3a1e4f6bde5 249 SMART SM00382 29 222 2.4E-10 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS08235 632f286c94c544b066619e23b2ac30ce 110 PANTHER PTHR34703 3 110 3.3E-38 T 13-09-2016 THL1_RS08235 632f286c94c544b066619e23b2ac30ce 110 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 12 98 8.1E-26 T 13-09-2016 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 THL1_RS08235 632f286c94c544b066619e23b2ac30ce 110 Pfam PF03334 Na+/H+ antiporter subunit 12 92 3.3E-26 T 13-09-2016 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 THL1_RS08235 632f286c94c544b066619e23b2ac30ce 110 PANTHER PTHR34703:SF1 3 110 3.3E-38 T 13-09-2016 THL1_RS19035 dd1268f7a217eada72116f1e001d6c21 349 Gene3D G3DSA:3.30.360.10 139 347 1.7E-37 T 13-09-2016 THL1_RS19035 dd1268f7a217eada72116f1e001d6c21 349 SUPERFAMILY SSF51735 4 150 5.12E-40 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS19035 dd1268f7a217eada72116f1e001d6c21 349 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 207 7.1E-5 T 13-09-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 THL1_RS19035 dd1268f7a217eada72116f1e001d6c21 349 SUPERFAMILY SSF55347 125 323 5.23E-27 T 13-09-2016 THL1_RS19035 dd1268f7a217eada72116f1e001d6c21 349 PANTHER PTHR22604:SF123 1 349 3.3E-79 T 13-09-2016 THL1_RS19035 dd1268f7a217eada72116f1e001d6c21 349 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 121 1.8E-22 T 13-09-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 THL1_RS19035 dd1268f7a217eada72116f1e001d6c21 349 Gene3D G3DSA:3.40.50.720 1 138 3.6E-36 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS19035 dd1268f7a217eada72116f1e001d6c21 349 PANTHER PTHR22604 1 349 3.3E-79 T 13-09-2016 THL1_RS14275 39a10e5930d046bcd01c61da8d9b0749 383 SMART SM00729 18 221 6.4E-5 T 13-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THL1_RS14275 39a10e5930d046bcd01c61da8d9b0749 383 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 24 35 - T 13-09-2016 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 THL1_RS14275 39a10e5930d046bcd01c61da8d9b0749 383 PANTHER PTHR11228:SF32 15 353 2.8E-116 T 13-09-2016 THL1_RS14275 39a10e5930d046bcd01c61da8d9b0749 383 Pfam PF13353 4Fe-4S single cluster domain 25 109 3.3E-7 T 13-09-2016 THL1_RS14275 39a10e5930d046bcd01c61da8d9b0749 383 PIRSF PIRSF037420 4 364 5.6E-134 T 13-09-2016 IPR017200 Coenzyme PQQ synthesis protein E UniPathway: UPA00539 THL1_RS14275 39a10e5930d046bcd01c61da8d9b0749 383 Pfam PF13186 Iron-sulfur cluster-binding domain 251 316 4.6E-9 T 13-09-2016 IPR023885 4Fe4S-binding SPASM domain THL1_RS14275 39a10e5930d046bcd01c61da8d9b0749 383 TIGRFAM TIGR02109 PQQ_syn_pqqE: coenzyme PQQ biosynthesis enzyme PqqE 14 373 1.8E-186 T 13-09-2016 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 UniPathway: UPA00539 THL1_RS14275 39a10e5930d046bcd01c61da8d9b0749 383 Pfam PF04055 Radical SAM superfamily 24 179 3.7E-22 T 13-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 THL1_RS14275 39a10e5930d046bcd01c61da8d9b0749 383 Hamap MF_00660 Coenzyme PQQ synthesis protein E [pqqE]. 1 383 198.36 T 13-09-2016 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 UniPathway: UPA00539 THL1_RS14275 39a10e5930d046bcd01c61da8d9b0749 383 Gene3D G3DSA:3.20.20.70 14 334 2.1E-70 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS14275 39a10e5930d046bcd01c61da8d9b0749 383 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 259 343 2.1E-7 T 13-09-2016 IPR023885 4Fe4S-binding SPASM domain THL1_RS14275 39a10e5930d046bcd01c61da8d9b0749 383 SUPERFAMILY SSF102114 16 325 1.29E-76 T 13-09-2016 THL1_RS14275 39a10e5930d046bcd01c61da8d9b0749 383 PANTHER PTHR11228 15 353 2.8E-116 T 13-09-2016 THL1_RS27125 874db0663143a17fca2aae2f62558da9 301 Pfam PF08443 RimK-like ATP-grasp domain 98 285 2.9E-68 T 13-09-2016 IPR013651 ATP-grasp fold, RimK-type THL1_RS27125 874db0663143a17fca2aae2f62558da9 301 PANTHER PTHR21621 1 289 1.9E-127 T 13-09-2016 THL1_RS27125 874db0663143a17fca2aae2f62558da9 301 Gene3D G3DSA:3.30.1490.20 103 171 8.4E-7 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS27125 874db0663143a17fca2aae2f62558da9 301 Gene3D G3DSA:3.40.50.20 8 102 4.8E-17 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS27125 874db0663143a17fca2aae2f62558da9 301 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 2 285 3.6E-85 T 13-09-2016 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 THL1_RS27125 874db0663143a17fca2aae2f62558da9 301 Gene3D G3DSA:3.30.470.20 172 276 1.3E-35 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS27125 874db0663143a17fca2aae2f62558da9 301 PANTHER PTHR21621:SF0 1 289 1.9E-127 T 13-09-2016 THL1_RS27125 874db0663143a17fca2aae2f62558da9 301 SUPERFAMILY SSF56059 98 289 2.36E-48 T 13-09-2016 THL1_RS27125 874db0663143a17fca2aae2f62558da9 301 Hamap MF_01552 Ribosomal protein S6--L-glutamate ligase [rimK]. 1 295 54.845 T 13-09-2016 IPR023533 Ribosomal protein S6--L-glutamate ligase RimK THL1_RS24470 fd88f2b9d2cfa8fd179c160ae7bd4e0c 217 Pfam PF01810 LysE type translocator 19 213 6.9E-50 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS24470 fd88f2b9d2cfa8fd179c160ae7bd4e0c 217 TIGRFAM TIGR00949 2A76: homoserine/Threonine efflux protein 24 211 1.9E-56 T 13-09-2016 IPR004778 Homoserine/Threonine efflux protein GO:0016021 THL1_RS24470 fd88f2b9d2cfa8fd179c160ae7bd4e0c 217 PANTHER PTHR30086 5 212 9.4E-115 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS24470 fd88f2b9d2cfa8fd179c160ae7bd4e0c 217 PIRSF PIRSF006324 4 216 8.9E-55 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS24470 fd88f2b9d2cfa8fd179c160ae7bd4e0c 217 PANTHER PTHR30086:SF15 5 212 9.4E-115 T 13-09-2016 THL1_RS21255 51770a96e6258ccceb2b13f2b987add3 134 PANTHER PTHR36530:SF2 8 134 2.2E-37 T 13-09-2016 THL1_RS21255 51770a96e6258ccceb2b13f2b987add3 134 SUPERFAMILY SSF141066 31 133 5.23E-30 T 13-09-2016 IPR018990 Proteinase inhibitor I42, chagasin THL1_RS21255 51770a96e6258ccceb2b13f2b987add3 134 Pfam PF09394 Chagasin family peptidase inhibitor I42 42 130 1.9E-23 T 13-09-2016 IPR018990 Proteinase inhibitor I42, chagasin THL1_RS21255 51770a96e6258ccceb2b13f2b987add3 134 PANTHER PTHR36530 8 134 2.2E-37 T 13-09-2016 THL1_RS23965 07967382935f822e43888d68702e2058 251 Pfam PF00899 ThiF family 10 243 2.7E-61 T 13-09-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 THL1_RS23965 07967382935f822e43888d68702e2058 251 SUPERFAMILY SSF69572 2 247 1.96E-85 T 13-09-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 THL1_RS23965 07967382935f822e43888d68702e2058 251 Gene3D G3DSA:3.40.50.720 2 247 1.3E-73 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23965 07967382935f822e43888d68702e2058 251 PANTHER PTHR10953 1 247 3.6E-90 T 13-09-2016 THL1_RS23965 07967382935f822e43888d68702e2058 251 PANTHER PTHR10953:SF158 1 247 3.6E-90 T 13-09-2016 THL1_RS26255 1a32a989c26f57f82300e037631bc872 147 Pfam PF14539 Domain of unknown function (DUF4442) 16 137 6.8E-17 T 13-09-2016 IPR027961 Protein of unknown function DUF4442 THL1_RS26255 1a32a989c26f57f82300e037631bc872 147 SUPERFAMILY SSF54637 7 144 3.07E-27 T 13-09-2016 IPR029069 HotDog domain THL1_RS26255 1a32a989c26f57f82300e037631bc872 147 Gene3D G3DSA:3.10.129.10 4 146 9.5E-41 T 13-09-2016 IPR029069 HotDog domain THL1_RS22935 e3c24f8beb9c6964fe17454a8d1284d0 232 Gene3D G3DSA:3.40.50.1240 66 175 1.7E-9 T 13-09-2016 IPR029033 Histidine phosphatase superfamily THL1_RS22935 e3c24f8beb9c6964fe17454a8d1284d0 232 SUPERFAMILY SSF53254 66 177 6.16E-13 T 13-09-2016 IPR029033 Histidine phosphatase superfamily THL1_RS27350 0b335ee6cef4a06f0b9d7b00ea8d4a73 218 PANTHER PTHR10224 1 217 1.8E-125 T 13-09-2016 THL1_RS27350 0b335ee6cef4a06f0b9d7b00ea8d4a73 218 PIRSF PIRSF006320 2 217 6.0E-107 T 13-09-2016 IPR026041 Enhancing lycopene biosynthesis protein 2 THL1_RS27350 0b335ee6cef4a06f0b9d7b00ea8d4a73 218 SUPERFAMILY SSF52317 3 217 2.45E-65 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS27350 0b335ee6cef4a06f0b9d7b00ea8d4a73 218 Pfam PF01965 DJ-1/PfpI family 15 189 3.2E-8 T 13-09-2016 IPR002818 DJ-1/PfpI THL1_RS27350 0b335ee6cef4a06f0b9d7b00ea8d4a73 218 Gene3D G3DSA:3.40.50.880 1 217 4.2E-102 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS26970 73975d045676d5cd45ff9d04e371e6e4 290 Pfam PF00483 Nucleotidyl transferase 2 237 4.0E-69 T 13-09-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 THL1_RS26970 73975d045676d5cd45ff9d04e371e6e4 290 Gene3D G3DSA:3.90.550.10 1 265 4.0E-70 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS26970 73975d045676d5cd45ff9d04e371e6e4 290 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 3.8E-155 T 13-09-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 THL1_RS26970 73975d045676d5cd45ff9d04e371e6e4 290 PANTHER PTHR22572:SF105 2 267 4.4E-172 T 13-09-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 THL1_RS26970 73975d045676d5cd45ff9d04e371e6e4 290 PANTHER PTHR22572 2 267 4.4E-172 T 13-09-2016 THL1_RS26970 73975d045676d5cd45ff9d04e371e6e4 290 SUPERFAMILY SSF53448 1 285 7.21E-93 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS03830 67edb841ae42f555c25364e20dcf7e59 217 PANTHER PTHR18895:SF3 57 176 9.7E-22 T 13-09-2016 THL1_RS03830 67edb841ae42f555c25364e20dcf7e59 217 SUPERFAMILY SSF53335 19 160 5.48E-26 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS03830 67edb841ae42f555c25364e20dcf7e59 217 PANTHER PTHR18895 57 176 9.7E-22 T 13-09-2016 THL1_RS03830 67edb841ae42f555c25364e20dcf7e59 217 Gene3D G3DSA:3.40.50.150 46 181 3.0E-37 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS03830 67edb841ae42f555c25364e20dcf7e59 217 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 81 153 1.5E-16 T 13-09-2016 THL1_RS13015 1dde5a771734255fba8e3112cf61a636 260 Pfam PF05235 CHAD domain 22 212 2.2E-20 T 13-09-2016 IPR007899 CHAD domain THL1_RS13015 1dde5a771734255fba8e3112cf61a636 260 SMART SM00880 10 250 1.7E-23 T 13-09-2016 IPR007899 CHAD domain THL1_RS15965 301ddf22433f381b888a5a2f3c0c0420 202 Gene3D G3DSA:3.40.50.360 1 200 4.5E-61 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS15965 301ddf22433f381b888a5a2f3c0c0420 202 PANTHER PTHR10204 1 198 1.8E-84 T 13-09-2016 THL1_RS15965 301ddf22433f381b888a5a2f3c0c0420 202 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 199 31.36 T 13-09-2016 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 THL1_RS15965 301ddf22433f381b888a5a2f3c0c0420 202 SUPERFAMILY SSF52218 1 198 2.17E-51 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS15965 301ddf22433f381b888a5a2f3c0c0420 202 Pfam PF02525 Flavodoxin-like fold 1 191 1.0E-45 T 13-09-2016 IPR003680 Flavodoxin-like fold THL1_RS15965 301ddf22433f381b888a5a2f3c0c0420 202 PANTHER PTHR10204:SF37 1 198 1.8E-84 T 13-09-2016 THL1_RS27320 c8a42866a39fa158d647f93d73ecbb6f 108 Gene3D G3DSA:3.40.30.10 2 107 4.1E-39 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS27320 c8a42866a39fa158d647f93d73ecbb6f 108 Pfam PF00085 Thioredoxin 6 106 3.0E-35 T 13-09-2016 IPR013766 Thioredoxin domain GO:0045454 THL1_RS27320 c8a42866a39fa158d647f93d73ecbb6f 108 PRINTS PR00421 Thioredoxin family signature 72 83 6.2E-10 T 13-09-2016 THL1_RS27320 c8a42866a39fa158d647f93d73ecbb6f 108 PRINTS PR00421 Thioredoxin family signature 32 41 6.2E-10 T 13-09-2016 THL1_RS27320 c8a42866a39fa158d647f93d73ecbb6f 108 PRINTS PR00421 Thioredoxin family signature 24 32 6.2E-10 T 13-09-2016 THL1_RS27320 c8a42866a39fa158d647f93d73ecbb6f 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 13-09-2016 IPR017937 Thioredoxin, conserved site GO:0045454 THL1_RS27320 c8a42866a39fa158d647f93d73ecbb6f 108 SUPERFAMILY SSF52833 4 106 3.82E-39 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS27320 c8a42866a39fa158d647f93d73ecbb6f 108 PANTHER PTHR10438 5 108 6.2E-38 T 13-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THL1_RS27320 c8a42866a39fa158d647f93d73ecbb6f 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 1.2E-39 T 13-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THL1_RS27320 c8a42866a39fa158d647f93d73ecbb6f 108 PIRSF PIRSF000077 2 108 4.6E-46 T 13-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THL1_RS07610 807b64d0d4322b6bdf00aef413641314 407 Pfam PF02264 LamB porin 27 406 5.1E-123 T 13-09-2016 IPR003192 Porin, LamB type GO:0006810|GO:0016020 THL1_RS07610 807b64d0d4322b6bdf00aef413641314 407 SUPERFAMILY SSF56935 25 406 7.94E-122 T 13-09-2016 THL1_RS07610 807b64d0d4322b6bdf00aef413641314 407 ProDom PD008788 PORIN MEMBRANE PRECURSOR SIGNAL MALTOPORIN OUTER ION TRANSMEMBRANE RECEPTOR LAMB 32 401 2.0E-158 T 13-09-2016 IPR003192 Porin, LamB type GO:0006810|GO:0016020 THL1_RS07610 807b64d0d4322b6bdf00aef413641314 407 Gene3D G3DSA:2.40.170.10 25 406 7.6E-120 T 13-09-2016 IPR003192 Porin, LamB type GO:0006810|GO:0016020 THL1_RS07610 807b64d0d4322b6bdf00aef413641314 407 PANTHER PTHR38762 1 406 1.1E-56 T 13-09-2016 THL1_RS16825 0d84e2cc939970a59316c4756632de29 121 SUPERFAMILY SSF52091 7 120 3.61E-20 T 13-09-2016 IPR002645 STAS domain THL1_RS16825 0d84e2cc939970a59316c4756632de29 121 Pfam PF11964 SpoIIAA-like 12 120 7.4E-11 T 13-09-2016 IPR021866 SpoIIAA-like THL1_RS16825 0d84e2cc939970a59316c4756632de29 121 Gene3D G3DSA:3.40.50.10600 1 120 3.3E-17 T 13-09-2016 IPR021866 SpoIIAA-like THL1_RS02770 11a6ddc048e061dcfb3b4c5c8adb9d49 297 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 182 200 2.2E-7 T 13-09-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THL1_RS02770 11a6ddc048e061dcfb3b4c5c8adb9d49 297 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 114 127 2.2E-7 T 13-09-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THL1_RS02770 11a6ddc048e061dcfb3b4c5c8adb9d49 297 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 240 253 2.2E-7 T 13-09-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THL1_RS02770 11a6ddc048e061dcfb3b4c5c8adb9d49 297 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 258 271 2.2E-7 T 13-09-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THL1_RS02770 11a6ddc048e061dcfb3b4c5c8adb9d49 297 PANTHER PTHR34047 55 247 3.7E-60 T 13-09-2016 THL1_RS02770 11a6ddc048e061dcfb3b4c5c8adb9d49 297 SUPERFAMILY SSF56672 68 295 1.42E-47 T 13-09-2016 THL1_RS02770 11a6ddc048e061dcfb3b4c5c8adb9d49 297 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 119 296 4.6E-41 T 13-09-2016 IPR000477 Reverse transcriptase domain THL1_RS02770 11a6ddc048e061dcfb3b4c5c8adb9d49 297 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 64 297 6.6E-94 T 13-09-2016 IPR030931 Group II intron reverse transcriptase/maturase THL1_RS26425 fe84a72e7565819522445063b6d72e2d 205 PANTHER PTHR38693:SF1 1 205 5.8E-57 T 13-09-2016 THL1_RS26425 fe84a72e7565819522445063b6d72e2d 205 PANTHER PTHR38693 1 205 5.8E-57 T 13-09-2016 THL1_RS26425 fe84a72e7565819522445063b6d72e2d 205 Pfam PF02036 SCP-2 sterol transfer family 14 111 4.6E-15 T 13-09-2016 IPR003033 SCP2 sterol-binding domain THL1_RS26425 fe84a72e7565819522445063b6d72e2d 205 SUPERFAMILY SSF55718 25 119 2.39E-6 T 13-09-2016 IPR003033 SCP2 sterol-binding domain THL1_RS02690 a6d58491509b66dcf910bfe8d956bd24 400 Pfam PF13356 Domain of unknown function (DUF4102) 3 88 7.4E-20 T 13-09-2016 IPR025166 Domain of unknown function DUF4102 THL1_RS02690 a6d58491509b66dcf910bfe8d956bd24 400 Pfam PF00589 Phage integrase family 207 373 6.6E-22 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS02690 a6d58491509b66dcf910bfe8d956bd24 400 PANTHER PTHR30629:SF3 1 391 7.4E-126 T 13-09-2016 THL1_RS02690 a6d58491509b66dcf910bfe8d956bd24 400 Gene3D G3DSA:1.10.443.10 205 381 1.2E-24 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS02690 a6d58491509b66dcf910bfe8d956bd24 400 SUPERFAMILY SSF56349 98 384 2.94E-59 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS02690 a6d58491509b66dcf910bfe8d956bd24 400 PANTHER PTHR30629 1 391 7.4E-126 T 13-09-2016 THL1_RS02690 a6d58491509b66dcf910bfe8d956bd24 400 Gene3D G3DSA:1.10.150.130 98 198 1.2E-16 T 13-09-2016 IPR023109 Integrase/recombinase, N-terminal THL1_RS04260 ba036cf42bb9bda3007d6f2af08b6522 208 Hamap MF_00013 Octanoyltransferase [lipB]. 5 207 37.773 T 13-09-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 THL1_RS04260 ba036cf42bb9bda3007d6f2af08b6522 208 SUPERFAMILY SSF55681 5 207 1.33E-70 T 13-09-2016 THL1_RS04260 ba036cf42bb9bda3007d6f2af08b6522 208 Pfam PF03099 Biotin/lipoate A/B protein ligase family 59 159 2.5E-9 T 13-09-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 THL1_RS04260 ba036cf42bb9bda3007d6f2af08b6522 208 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 27 200 7.1E-65 T 13-09-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 THL1_RS04260 ba036cf42bb9bda3007d6f2af08b6522 208 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 75 128 5.0E-8 T 13-09-2016 THL1_RS04260 ba036cf42bb9bda3007d6f2af08b6522 208 PANTHER PTHR10993 4 206 6.0E-73 T 13-09-2016 THL1_RS04260 ba036cf42bb9bda3007d6f2af08b6522 208 PIRSF PIRSF016262 2 208 4.5E-59 T 13-09-2016 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 THL1_RS04260 ba036cf42bb9bda3007d6f2af08b6522 208 Gene3D G3DSA:3.90.1550.10 5 204 8.6E-71 T 13-09-2016 THL1_RS04260 ba036cf42bb9bda3007d6f2af08b6522 208 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 71 86 - T 13-09-2016 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 THL1_RS26520 38d6611a94aa0f3394b89639240a8c14 271 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS26520 38d6611a94aa0f3394b89639240a8c14 271 Pfam PF00005 ABC transporter 44 191 1.5E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS26520 38d6611a94aa0f3394b89639240a8c14 271 SMART SM00382 52 240 3.8E-19 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS26520 38d6611a94aa0f3394b89639240a8c14 271 PANTHER PTHR24220 5 15 5.7E-151 T 13-09-2016 THL1_RS26520 38d6611a94aa0f3394b89639240a8c14 271 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 36 266 3.4E-110 T 13-09-2016 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 THL1_RS26520 38d6611a94aa0f3394b89639240a8c14 271 PANTHER PTHR24220:SF374 5 15 5.7E-151 T 13-09-2016 THL1_RS26520 38d6611a94aa0f3394b89639240a8c14 271 PANTHER PTHR24220 40 266 5.7E-151 T 13-09-2016 THL1_RS26520 38d6611a94aa0f3394b89639240a8c14 271 SUPERFAMILY SSF52540 36 263 1.6E-72 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26520 38d6611a94aa0f3394b89639240a8c14 271 PANTHER PTHR24220:SF374 40 266 5.7E-151 T 13-09-2016 THL1_RS26520 38d6611a94aa0f3394b89639240a8c14 271 Gene3D G3DSA:3.40.50.300 40 264 1.0E-74 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21855 b28e08a73d5f451a8f61010e58861d8a 490 PANTHER PTHR11699 2 488 2.0E-219 T 13-09-2016 THL1_RS21855 b28e08a73d5f451a8f61010e58861d8a 490 SUPERFAMILY SSF53720 2 482 1.7E-165 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS21855 b28e08a73d5f451a8f61010e58861d8a 490 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS21855 b28e08a73d5f451a8f61010e58861d8a 490 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS21855 b28e08a73d5f451a8f61010e58861d8a 490 Gene3D G3DSA:3.40.605.10 3 262 4.4E-92 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS21855 b28e08a73d5f451a8f61010e58861d8a 490 Pfam PF00171 Aldehyde dehydrogenase family 12 475 9.5E-168 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS21855 b28e08a73d5f451a8f61010e58861d8a 490 Gene3D G3DSA:3.40.309.10 263 441 9.7E-71 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS28085 a39d3a261b7178452a6d04786c5c903e 177 Pfam PF11736 Protein of unknown function (DUF3299) 24 169 3.1E-43 T 13-09-2016 IPR021727 Protein of unknown function DUF3299 THL1_RS25685 24436eb218a0a83a9f659f900feac02a 428 Pfam PF02653 Branched-chain amino acid transport system / permease component 120 405 3.5E-47 T 13-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 THL1_RS25685 24436eb218a0a83a9f659f900feac02a 428 PANTHER PTHR30482:SF9 69 427 1.0E-173 T 13-09-2016 THL1_RS25685 24436eb218a0a83a9f659f900feac02a 428 Pfam PF11862 Domain of unknown function (DUF3382) 14 112 7.0E-19 T 13-09-2016 IPR021807 High-affinity branched-chain amino acid transport system permease, LivHM, N-terminal THL1_RS25685 24436eb218a0a83a9f659f900feac02a 428 PANTHER PTHR30482 69 427 1.0E-173 T 13-09-2016 THL1_RS00490 4909fff71761edacd88ad31845ebf9d9 105 TIGRFAM TIGR02448 TIGR02448: conserverd hypothetical protein 1 104 2.4E-38 T 13-09-2016 IPR012661 Conserved hypothetical protein CHP02448 THL1_RS00490 4909fff71761edacd88ad31845ebf9d9 105 Pfam PF09498 Protein of unknown function (DUF2388) 35 104 1.5E-32 T 13-09-2016 IPR012661 Conserved hypothetical protein CHP02448 THL1_RS10345 7e4c68188e45a201865be6fe03a08a0b 341 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 335 51.559 T 13-09-2016 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS10345 7e4c68188e45a201865be6fe03a08a0b 341 SUPERFAMILY SSF51395 1 334 2.89E-106 T 13-09-2016 THL1_RS10345 7e4c68188e45a201865be6fe03a08a0b 341 PIRSF PIRSF000164 15 339 1.3E-94 T 13-09-2016 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 Reactome: REACT_1698 THL1_RS10345 7e4c68188e45a201865be6fe03a08a0b 341 Pfam PF01180 Dihydroorotate dehydrogenase 44 333 2.9E-87 T 13-09-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 THL1_RS10345 7e4c68188e45a201865be6fe03a08a0b 341 PANTHER PTHR11938 8 337 1.2E-97 T 13-09-2016 THL1_RS10345 7e4c68188e45a201865be6fe03a08a0b 341 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 79 98 - T 13-09-2016 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 THL1_RS10345 7e4c68188e45a201865be6fe03a08a0b 341 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 2 336 5.4E-132 T 13-09-2016 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS10345 7e4c68188e45a201865be6fe03a08a0b 341 Gene3D G3DSA:3.20.20.70 1 336 3.4E-125 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS04940 045bf0193d8f71b4d5246c638cbe7244 1141 Pfam PF05567 Neisseria PilC beta-propeller domain 631 971 1.2E-67 T 13-09-2016 IPR008707 PilC beta-propeller domain THL1_RS04940 045bf0193d8f71b4d5246c638cbe7244 1141 SUPERFAMILY SSF50998 675 997 6.28E-8 T 13-09-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THL1_RS27635 c275e8a7709fec68b94a2ab9dd86e00a 215 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 13-09-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS27635 c275e8a7709fec68b94a2ab9dd86e00a 215 PANTHER PTHR11002 1 208 1.2E-127 T 13-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS27635 c275e8a7709fec68b94a2ab9dd86e00a 215 SUPERFAMILY SSF53056 1 203 1.11E-73 T 13-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS27635 c275e8a7709fec68b94a2ab9dd86e00a 215 PANTHER PTHR11002:SF20 1 208 1.2E-127 T 13-09-2016 THL1_RS27635 c275e8a7709fec68b94a2ab9dd86e00a 215 SMART SM00947 30 193 3.1E-66 T 13-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS27635 c275e8a7709fec68b94a2ab9dd86e00a 215 Pfam PF00484 Carbonic anhydrase 37 188 2.3E-50 T 13-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS27635 c275e8a7709fec68b94a2ab9dd86e00a 215 Gene3D G3DSA:3.40.1050.10 1 202 1.8E-76 T 13-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS02040 c8b23dd8d0bcc2ce34824d14e9bf055e 358 SUPERFAMILY SSF53383 11 350 1.36E-65 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS02040 c8b23dd8d0bcc2ce34824d14e9bf055e 358 Gene3D G3DSA:3.90.1150.10 224 351 3.3E-24 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS02040 c8b23dd8d0bcc2ce34824d14e9bf055e 358 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 201 214 - T 13-09-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 THL1_RS02040 c8b23dd8d0bcc2ce34824d14e9bf055e 358 PANTHER PTHR11751:SF301 33 352 3.4E-58 T 13-09-2016 THL1_RS02040 c8b23dd8d0bcc2ce34824d14e9bf055e 358 PANTHER PTHR11751 33 352 3.4E-58 T 13-09-2016 THL1_RS02040 c8b23dd8d0bcc2ce34824d14e9bf055e 358 Pfam PF00155 Aminotransferase class I and II 42 347 4.5E-36 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS02040 c8b23dd8d0bcc2ce34824d14e9bf055e 358 Gene3D G3DSA:3.40.640.10 42 223 1.2E-38 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS12375 f60a7bd52cace15fc29e3cfa485e9410 120 PANTHER PTHR33473 8 120 6.9E-39 T 13-09-2016 THL1_RS12375 f60a7bd52cace15fc29e3cfa485e9410 120 Gene3D G3DSA:3.30.1390.10 20 119 1.2E-43 T 13-09-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like THL1_RS12375 f60a7bd52cace15fc29e3cfa485e9410 120 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 19 114 28.909 T 13-09-2016 IPR022935 ATP-dependent Clp protease adaptor protein ClpS THL1_RS12375 f60a7bd52cace15fc29e3cfa485e9410 120 SUPERFAMILY SSF54736 35 118 4.18E-32 T 13-09-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like THL1_RS12375 f60a7bd52cace15fc29e3cfa485e9410 120 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 37 115 1.2E-34 T 13-09-2016 IPR003769 Adaptor protein ClpS, core GO:0030163 THL1_RS05355 1e68d922809ee5d7bfe1963f2856bbb1 154 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 8 147 5.5E-35 T 13-09-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- THL1_RS05355 1e68d922809ee5d7bfe1963f2856bbb1 154 SUPERFAMILY SSF55804 1 147 1.96E-42 T 13-09-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 THL1_RS05355 1e68d922809ee5d7bfe1963f2856bbb1 154 TIGRFAM TIGR01419 nitro_reg_IIA: PTS IIA-like nitrogen-regulatory protein PtsN 3 149 5.6E-55 T 13-09-2016 IPR006320 Phosphotransferase system, IIA-like nitrogen-regulatory protein PtsN GO:0008982|GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- THL1_RS05355 1e68d922809ee5d7bfe1963f2856bbb1 154 PANTHER PTHR30505 1 151 3.7E-68 T 13-09-2016 THL1_RS05355 1e68d922809ee5d7bfe1963f2856bbb1 154 Gene3D G3DSA:3.40.930.10 1 149 2.7E-42 T 13-09-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- THL1_RS05355 1e68d922809ee5d7bfe1963f2856bbb1 154 PANTHER PTHR30505:SF6 1 151 3.7E-68 T 13-09-2016 THL1_RS19855 ff064a953cdfaec65d7b09b8847944e1 155 Pfam PF05130 FlgN protein 1 144 3.0E-32 T 13-09-2016 IPR007809 FlgN-like protein GO:0005515|GO:0044780 THL1_RS19855 ff064a953cdfaec65d7b09b8847944e1 155 SUPERFAMILY SSF140566 1 129 5.75E-30 T 13-09-2016 IPR007809 FlgN-like protein GO:0005515|GO:0044780 THL1_RS19855 ff064a953cdfaec65d7b09b8847944e1 155 Gene3D G3DSA:1.20.58.300 1 129 6.3E-37 T 13-09-2016 IPR007809 FlgN-like protein GO:0005515|GO:0044780 THL1_RS22450 d442fe3dfccab4b6651528953fc68c95 359 SUPERFAMILY SSF102405 68 263 1.53E-47 T 13-09-2016 THL1_RS22450 d442fe3dfccab4b6651528953fc68c95 359 PANTHER PTHR31223:SF1 31 307 1.3E-138 T 13-09-2016 THL1_RS22450 d442fe3dfccab4b6651528953fc68c95 359 Gene3D G3DSA:3.40.50.450 63 351 1.2E-68 T 13-09-2016 THL1_RS22450 d442fe3dfccab4b6651528953fc68c95 359 Pfam PF03641 Possible lysine decarboxylase 130 262 2.9E-27 T 13-09-2016 IPR031100 LOG family THL1_RS22450 d442fe3dfccab4b6651528953fc68c95 359 PANTHER PTHR31223 31 307 1.3E-138 T 13-09-2016 THL1_RS03620 87415051e482b74ee854454881c8e091 144 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 142 8.0E-45 T 13-09-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 THL1_RS03620 87415051e482b74ee854454881c8e091 144 Gene3D G3DSA:3.100.10.10 32 143 1.3E-23 T 13-09-2016 THL1_RS03620 87415051e482b74ee854454881c8e091 144 SUPERFAMILY SSF52080 4 142 2.62E-43 T 13-09-2016 IPR021131 Ribosomal protein L18e/L15P THL1_RS03620 87415051e482b74ee854454881c8e091 144 ProSitePatterns PS00475 Ribosomal protein L15 signature. 109 139 - T 13-09-2016 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03620 87415051e482b74ee854454881c8e091 144 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 143 5.7E-28 T 13-09-2016 IPR021131 Ribosomal protein L18e/L15P THL1_RS03620 87415051e482b74ee854454881c8e091 144 PANTHER PTHR12934 1 143 1.5E-67 T 13-09-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 THL1_RS03620 87415051e482b74ee854454881c8e091 144 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 143 17.812 T 13-09-2016 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 THL1_RS02820 2fbf802c90cbd053b174981ae403a161 482 Pfam PF00171 Aldehyde dehydrogenase family 19 477 2.8E-173 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS02820 2fbf802c90cbd053b174981ae403a161 482 PANTHER PTHR11699 2 480 2.9E-301 T 13-09-2016 THL1_RS02820 2fbf802c90cbd053b174981ae403a161 482 Gene3D G3DSA:3.40.605.10 10 267 1.1E-104 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS02820 2fbf802c90cbd053b174981ae403a161 482 Gene3D G3DSA:3.40.309.10 268 453 1.9E-69 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS02820 2fbf802c90cbd053b174981ae403a161 482 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS02820 2fbf802c90cbd053b174981ae403a161 482 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS02820 2fbf802c90cbd053b174981ae403a161 482 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 30 476 5.8E-235 T 13-09-2016 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 UniPathway: UPA00733 THL1_RS02820 2fbf802c90cbd053b174981ae403a161 482 PANTHER PTHR11699:SF49 2 480 2.9E-301 T 13-09-2016 THL1_RS02820 2fbf802c90cbd053b174981ae403a161 482 SUPERFAMILY SSF53720 5 481 5.76E-176 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS07795 2fbf802c90cbd053b174981ae403a161 482 Pfam PF00171 Aldehyde dehydrogenase family 19 477 2.8E-173 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS07795 2fbf802c90cbd053b174981ae403a161 482 PANTHER PTHR11699 2 480 2.9E-301 T 13-09-2016 THL1_RS07795 2fbf802c90cbd053b174981ae403a161 482 Gene3D G3DSA:3.40.605.10 10 267 1.1E-104 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS07795 2fbf802c90cbd053b174981ae403a161 482 Gene3D G3DSA:3.40.309.10 268 453 1.9E-69 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS07795 2fbf802c90cbd053b174981ae403a161 482 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 282 293 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS07795 2fbf802c90cbd053b174981ae403a161 482 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 254 261 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS07795 2fbf802c90cbd053b174981ae403a161 482 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 30 476 5.8E-235 T 13-09-2016 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 UniPathway: UPA00733 THL1_RS07795 2fbf802c90cbd053b174981ae403a161 482 PANTHER PTHR11699:SF49 2 480 2.9E-301 T 13-09-2016 THL1_RS07795 2fbf802c90cbd053b174981ae403a161 482 SUPERFAMILY SSF53720 5 481 5.76E-176 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS21005 a10e22d5129e8a4803df1d4e9244a374 499 SUPERFAMILY SSF56112 165 452 4.37E-37 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS21005 a10e22d5129e8a4803df1d4e9244a374 499 Gene3D G3DSA:3.90.1200.10 292 447 3.0E-24 T 13-09-2016 THL1_RS21005 a10e22d5129e8a4803df1d4e9244a374 499 PANTHER PTHR21310 233 414 1.3E-13 T 13-09-2016 THL1_RS21005 a10e22d5129e8a4803df1d4e9244a374 499 Pfam PF01636 Phosphotransferase enzyme family 190 445 1.1E-25 T 13-09-2016 IPR002575 Aminoglycoside phosphotransferase THL1_RS21005 a10e22d5129e8a4803df1d4e9244a374 499 PANTHER PTHR21310:SF14 233 414 1.3E-13 T 13-09-2016 THL1_RS07300 6329c59fd7b6672e84a5f129ffcad2bf 493 Gene3D G3DSA:3.40.309.10 266 450 2.7E-71 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS07300 6329c59fd7b6672e84a5f129ffcad2bf 493 SUPERFAMILY SSF53720 4 483 8.51E-171 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS07300 6329c59fd7b6672e84a5f129ffcad2bf 493 PANTHER PTHR11699 4 483 2.6E-234 T 13-09-2016 THL1_RS07300 6329c59fd7b6672e84a5f129ffcad2bf 493 Gene3D G3DSA:3.40.605.10 5 265 1.2E-97 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS07300 6329c59fd7b6672e84a5f129ffcad2bf 493 Pfam PF00171 Aldehyde dehydrogenase family 14 477 1.1E-173 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS07300 6329c59fd7b6672e84a5f129ffcad2bf 493 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS07300 6329c59fd7b6672e84a5f129ffcad2bf 493 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS25320 fc2efe3aee62a4441d91942ff76c3960 92 Pfam PF12266 Protein of unknown function (DUF3613) 18 78 4.5E-18 T 13-09-2016 IPR022053 Protein of unknown function DUF3613 THL1_RS23700 e5b0313286eee88aa85c2f3c5523e238 213 SUPERFAMILY SSF56281 6 212 1.82E-52 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS23700 e5b0313286eee88aa85c2f3c5523e238 213 PANTHER PTHR11935:SF8 7 212 1.5E-58 T 13-09-2016 THL1_RS23700 e5b0313286eee88aa85c2f3c5523e238 213 Pfam PF00753 Metallo-beta-lactamase superfamily 15 195 2.0E-30 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS23700 e5b0313286eee88aa85c2f3c5523e238 213 SMART SM00849 18 195 6.5E-38 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS23700 e5b0313286eee88aa85c2f3c5523e238 213 PANTHER PTHR11935 7 212 1.5E-58 T 13-09-2016 THL1_RS23700 e5b0313286eee88aa85c2f3c5523e238 213 Gene3D G3DSA:3.60.15.10 3 212 4.1E-50 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS15990 553c0be174d4a0de9ddb45e42cea8791 103 Pfam PF11196 Protein of unknown function (DUF2834) 7 96 1.1E-5 T 13-09-2016 IPR021362 Protein of unknown function DUF2834 THL1_RS24185 70012a2e7eb27a9daad59aa4faf35236 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 9.2E-17 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS24185 70012a2e7eb27a9daad59aa4faf35236 293 SUPERFAMILY SSF46785 1 83 3.27E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS24185 70012a2e7eb27a9daad59aa4faf35236 293 Gene3D G3DSA:1.10.10.10 1 80 1.6E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS24185 70012a2e7eb27a9daad59aa4faf35236 293 PANTHER PTHR30126 1 290 8.1E-111 T 13-09-2016 THL1_RS24185 70012a2e7eb27a9daad59aa4faf35236 293 Gene3D G3DSA:3.40.190.10 81 197 9.5E-17 T 13-09-2016 THL1_RS24185 70012a2e7eb27a9daad59aa4faf35236 293 Gene3D G3DSA:3.40.190.10 198 265 3.6E-14 T 13-09-2016 THL1_RS24185 70012a2e7eb27a9daad59aa4faf35236 293 SUPERFAMILY SSF53850 89 290 4.5E-30 T 13-09-2016 THL1_RS24185 70012a2e7eb27a9daad59aa4faf35236 293 Pfam PF03466 LysR substrate binding domain 89 290 1.3E-33 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS24185 70012a2e7eb27a9daad59aa4faf35236 293 PANTHER PTHR30126:SF14 1 290 8.1E-111 T 13-09-2016 THL1_RS24185 70012a2e7eb27a9daad59aa4faf35236 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.9E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS24185 70012a2e7eb27a9daad59aa4faf35236 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.9E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS24185 70012a2e7eb27a9daad59aa4faf35236 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.9E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS22815 2ddfeb9b52d7dd02e32b217895d52cc5 226 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 216 1.4E-62 T 13-09-2016 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 THL1_RS22815 2ddfeb9b52d7dd02e32b217895d52cc5 226 PANTHER PTHR11735 1 137 2.0E-54 T 13-09-2016 THL1_RS22815 2ddfeb9b52d7dd02e32b217895d52cc5 226 SUPERFAMILY SSF53067 109 214 1.94E-25 T 13-09-2016 THL1_RS22815 2ddfeb9b52d7dd02e32b217895d52cc5 226 PANTHER PTHR11735:SF11 1 137 2.0E-54 T 13-09-2016 THL1_RS22815 2ddfeb9b52d7dd02e32b217895d52cc5 226 Gene3D G3DSA:3.30.420.40 4 133 2.0E-41 T 13-09-2016 THL1_RS22815 2ddfeb9b52d7dd02e32b217895d52cc5 226 SUPERFAMILY SSF53067 4 104 8.09E-28 T 13-09-2016 THL1_RS22815 2ddfeb9b52d7dd02e32b217895d52cc5 226 Pfam PF00814 Glycoprotease family 31 151 4.3E-27 T 13-09-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 THL1_RS02030 a731ef590e5b54467cc078a0bbeec38f 286 SUPERFAMILY SSF54506 143 274 1.04E-22 T 13-09-2016 THL1_RS02030 a731ef590e5b54467cc078a0bbeec38f 286 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 1 274 1.9E-48 T 13-09-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS02030 a731ef590e5b54467cc078a0bbeec38f 286 Gene3D G3DSA:3.10.310.10 1 121 3.7E-27 T 13-09-2016 THL1_RS02030 a731ef590e5b54467cc078a0bbeec38f 286 Pfam PF01678 Diaminopimelate epimerase 172 261 4.1E-8 T 13-09-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS02030 a731ef590e5b54467cc078a0bbeec38f 286 Pfam PF01678 Diaminopimelate epimerase 3 124 4.8E-18 T 13-09-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS02030 a731ef590e5b54467cc078a0bbeec38f 286 SUPERFAMILY SSF54506 1 126 1.46E-24 T 13-09-2016 THL1_RS02030 a731ef590e5b54467cc078a0bbeec38f 286 PANTHER PTHR31689 1 280 5.7E-44 T 13-09-2016 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS02030 a731ef590e5b54467cc078a0bbeec38f 286 Gene3D G3DSA:3.10.310.10 122 260 3.7E-22 T 13-09-2016 THL1_RS02030 a731ef590e5b54467cc078a0bbeec38f 286 PANTHER PTHR31689:SF0 1 280 5.7E-44 T 13-09-2016 THL1_RS10555 36409ece3eb3f40e0e868a6f736d9f17 232 Pfam PF02678 Pirin 12 118 3.4E-36 T 13-09-2016 IPR003829 Pirin, N-terminal domain THL1_RS10555 36409ece3eb3f40e0e868a6f736d9f17 232 PIRSF PIRSF006232 3 231 6.1E-53 T 13-09-2016 IPR012093 Pirin THL1_RS10555 36409ece3eb3f40e0e868a6f736d9f17 232 PANTHER PTHR13903:SF7 1 231 1.7E-102 T 13-09-2016 THL1_RS10555 36409ece3eb3f40e0e868a6f736d9f17 232 PANTHER PTHR13903 1 231 1.7E-102 T 13-09-2016 IPR012093 Pirin THL1_RS10555 36409ece3eb3f40e0e868a6f736d9f17 232 SUPERFAMILY SSF51182 1 231 3.43E-72 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS10555 36409ece3eb3f40e0e868a6f736d9f17 232 Gene3D G3DSA:2.60.120.10 5 231 8.8E-66 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS16475 2c1a18607cb3478f127602945907fc29 359 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS16475 2c1a18607cb3478f127602945907fc29 359 PANTHER PTHR24220 10 251 9.5E-129 T 13-09-2016 THL1_RS16475 2c1a18607cb3478f127602945907fc29 359 Pfam PF08402 TOBE domain 281 357 1.8E-7 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS16475 2c1a18607cb3478f127602945907fc29 359 PANTHER PTHR24220:SF150 10 251 9.5E-129 T 13-09-2016 THL1_RS16475 2c1a18607cb3478f127602945907fc29 359 SUPERFAMILY SSF52540 9 250 5.99E-83 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16475 2c1a18607cb3478f127602945907fc29 359 SUPERFAMILY SSF50331 244 358 8.5E-10 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS16475 2c1a18607cb3478f127602945907fc29 359 Pfam PF00005 ABC transporter 26 168 1.6E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS16475 2c1a18607cb3478f127602945907fc29 359 SMART SM00382 35 218 2.0E-16 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS16475 2c1a18607cb3478f127602945907fc29 359 Gene3D G3DSA:3.40.50.300 7 241 1.7E-77 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS23960 b32bc94b0681db7813d81f6ce1f5d758 264 PANTHER PTHR21198 1 264 1.8E-102 T 13-09-2016 THL1_RS23960 b32bc94b0681db7813d81f6ce1f5d758 264 PANTHER PTHR21198:SF2 1 264 1.8E-102 T 13-09-2016 THL1_RS23960 b32bc94b0681db7813d81f6ce1f5d758 264 TIGRFAM TIGR00067 glut_race: glutamate racemase 7 249 7.6E-67 T 13-09-2016 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS23960 b32bc94b0681db7813d81f6ce1f5d758 264 SUPERFAMILY SSF53681 6 108 2.42E-32 T 13-09-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS23960 b32bc94b0681db7813d81f6ce1f5d758 264 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 216 8.8E-37 T 13-09-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS23960 b32bc94b0681db7813d81f6ce1f5d758 264 Gene3D G3DSA:3.40.50.1860 5 174 2.9E-53 T 13-09-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS23960 b32bc94b0681db7813d81f6ce1f5d758 264 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 71 79 - T 13-09-2016 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS23960 b32bc94b0681db7813d81f6ce1f5d758 264 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 13-09-2016 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS23960 b32bc94b0681db7813d81f6ce1f5d758 264 SUPERFAMILY SSF53681 110 257 9.32E-40 T 13-09-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS23960 b32bc94b0681db7813d81f6ce1f5d758 264 Hamap MF_00258 Glutamate racemase [murI]. 5 256 37.511 T 13-09-2016 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS12425 3caf640b2f61af8888dae3789e445573 426 SUPERFAMILY SSF55681 116 423 5.88E-102 T 13-09-2016 THL1_RS12425 3caf640b2f61af8888dae3789e445573 426 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 424 41.716 T 13-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 THL1_RS12425 3caf640b2f61af8888dae3789e445573 426 Gene3D G3DSA:1.10.287.40 1 104 3.7E-25 T 13-09-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 THL1_RS12425 3caf640b2f61af8888dae3789e445573 426 SUPERFAMILY SSF46589 1 112 4.87E-30 T 13-09-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 THL1_RS12425 3caf640b2f61af8888dae3789e445573 426 Gene3D G3DSA:3.30.930.10 105 423 6.5E-145 T 13-09-2016 THL1_RS12425 3caf640b2f61af8888dae3789e445573 426 PIRSF PIRSF001529 1 426 1.2E-182 T 13-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 THL1_RS12425 3caf640b2f61af8888dae3789e445573 426 PRINTS PR00981 Seryl-tRNA synthetase signature 318 331 7.7E-34 T 13-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 THL1_RS12425 3caf640b2f61af8888dae3789e445573 426 PRINTS PR00981 Seryl-tRNA synthetase signature 266 278 7.7E-34 T 13-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 THL1_RS12425 3caf640b2f61af8888dae3789e445573 426 PRINTS PR00981 Seryl-tRNA synthetase signature 278 291 7.7E-34 T 13-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 THL1_RS12425 3caf640b2f61af8888dae3789e445573 426 PRINTS PR00981 Seryl-tRNA synthetase signature 353 369 7.7E-34 T 13-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 THL1_RS12425 3caf640b2f61af8888dae3789e445573 426 PRINTS PR00981 Seryl-tRNA synthetase signature 335 351 7.7E-34 T 13-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 THL1_RS12425 3caf640b2f61af8888dae3789e445573 426 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 419 9.4E-174 T 13-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 THL1_RS12425 3caf640b2f61af8888dae3789e445573 426 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 8.0E-30 T 13-09-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 THL1_RS12425 3caf640b2f61af8888dae3789e445573 426 PANTHER PTHR11778 1 425 1.2E-211 T 13-09-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 THL1_RS12425 3caf640b2f61af8888dae3789e445573 426 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 218 402 4.1E-37 T 13-09-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS22800 36aa3a5d8c424e7d916e2c1015455acb 275 SUPERFAMILY SSF51621 6 271 5.23E-60 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS22800 36aa3a5d8c424e7d916e2c1015455acb 275 PANTHER PTHR21631 1 250 1.6E-83 T 13-09-2016 THL1_RS22800 36aa3a5d8c424e7d916e2c1015455acb 275 PANTHER PTHR21631:SF18 1 250 1.6E-83 T 13-09-2016 THL1_RS22800 36aa3a5d8c424e7d916e2c1015455acb 275 Gene3D G3DSA:3.20.20.60 2 234 1.8E-60 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS22800 36aa3a5d8c424e7d916e2c1015455acb 275 Pfam PF13714 Phosphoenolpyruvate phosphomutase 11 251 2.8E-71 T 13-09-2016 THL1_RS08290 d814319828693d94e17f5cc984bb45d0 303 Gene3D G3DSA:2.40.50.100 45 78 1.0E-17 T 13-09-2016 THL1_RS08290 d814319828693d94e17f5cc984bb45d0 303 Gene3D G3DSA:2.40.50.100 152 186 1.0E-17 T 13-09-2016 THL1_RS08290 d814319828693d94e17f5cc984bb45d0 303 PANTHER PTHR30367:SF5 1 283 2.1E-127 T 13-09-2016 THL1_RS08290 d814319828693d94e17f5cc984bb45d0 303 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 228 2.5E-30 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS08290 d814319828693d94e17f5cc984bb45d0 303 Pfam PF13533 Biotin-lipoyl like 45 92 4.4E-17 T 13-09-2016 THL1_RS08290 d814319828693d94e17f5cc984bb45d0 303 Pfam PF13437 HlyD family secretion protein 155 234 4.8E-8 T 13-09-2016 THL1_RS08290 d814319828693d94e17f5cc984bb45d0 303 SUPERFAMILY SSF111369 43 202 5.23E-21 T 13-09-2016 THL1_RS08290 d814319828693d94e17f5cc984bb45d0 303 PANTHER PTHR30367 1 283 2.1E-127 T 13-09-2016 THL1_RS12000 8aa64e3f0531aa5b0e0243fddff606ca 234 Pfam PF00043 Glutathione S-transferase, C-terminal domain 129 222 1.2E-9 T 13-09-2016 IPR004046 Glutathione S-transferase, C-terminal THL1_RS12000 8aa64e3f0531aa5b0e0243fddff606ca 234 Pfam PF02798 Glutathione S-transferase, N-terminal domain 21 98 1.5E-13 T 13-09-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THL1_RS12000 8aa64e3f0531aa5b0e0243fddff606ca 234 PANTHER PTHR11260 21 231 3.2E-70 T 13-09-2016 THL1_RS12000 8aa64e3f0531aa5b0e0243fddff606ca 234 PANTHER PTHR11260:SF178 21 231 3.2E-70 T 13-09-2016 THL1_RS12000 8aa64e3f0531aa5b0e0243fddff606ca 234 Gene3D G3DSA:1.20.1050.10 102 225 1.5E-38 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS12000 8aa64e3f0531aa5b0e0243fddff606ca 234 Gene3D G3DSA:3.40.30.10 8 101 7.9E-30 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS12000 8aa64e3f0531aa5b0e0243fddff606ca 234 SUPERFAMILY SSF52833 12 103 2.11E-23 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS12000 8aa64e3f0531aa5b0e0243fddff606ca 234 SUPERFAMILY SSF47616 102 231 3.82E-31 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 SMART SM00387 236 356 7.0E-28 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 Gene3D G3DSA:3.30.565.10 199 356 3.5E-37 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 SUPERFAMILY SSF47384 127 194 4.71E-13 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 Gene3D G3DSA:1.10.287.130 129 189 1.0E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 SUPERFAMILY SSF55785 6 107 4.01E-10 T 13-09-2016 IPR000014 PAS domain THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 Gene3D G3DSA:3.30.450.20 6 111 2.8E-21 T 13-09-2016 THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 Pfam PF00512 His Kinase A (phospho-acceptor) domain 136 189 1.5E-15 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 SUPERFAMILY SSF55874 200 354 2.23E-34 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 SMART SM00091 6 74 4.4E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 Pfam PF08448 PAS fold 12 109 1.3E-6 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 SMART SM00388 132 197 1.5E-15 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 PANTHER PTHR24423:SF488 288 358 8.6E-159 T 13-09-2016 THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 PANTHER PTHR24423:SF488 7 272 8.6E-159 T 13-09-2016 THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 340 353 1.2E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 317 335 1.2E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 302 1.2E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 237 356 3.0E-14 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 PANTHER PTHR24423 288 358 8.6E-159 T 13-09-2016 THL1_RS26675 8c71b72ba1fa301073c1dd6bdc524dcc 361 PANTHER PTHR24423 7 272 8.6E-159 T 13-09-2016 THL1_RS23805 731d90f1bdab1a09442a623010ac1c84 711 SUPERFAMILY SSF58104 402 711 5.75E-81 T 13-09-2016 THL1_RS23805 731d90f1bdab1a09442a623010ac1c84 711 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 514 709 9.6E-50 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS23805 731d90f1bdab1a09442a623010ac1c84 711 PANTHER PTHR32089:SF34 121 711 2.6E-225 T 13-09-2016 THL1_RS23805 731d90f1bdab1a09442a623010ac1c84 711 PANTHER PTHR32089 121 711 2.6E-225 T 13-09-2016 THL1_RS23805 731d90f1bdab1a09442a623010ac1c84 711 SMART SM00283 449 710 3.4E-79 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS23805 731d90f1bdab1a09442a623010ac1c84 711 SMART SM00304 380 434 1.4E-10 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS23805 731d90f1bdab1a09442a623010ac1c84 711 Gene3D G3DSA:1.10.287.950 464 681 4.0E-58 T 13-09-2016 THL1_RS23805 731d90f1bdab1a09442a623010ac1c84 711 Gene3D G3DSA:3.30.450.20 206 345 1.1E-7 T 13-09-2016 THL1_RS23805 731d90f1bdab1a09442a623010ac1c84 711 Pfam PF00672 HAMP domain 362 430 5.9E-12 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS23805 731d90f1bdab1a09442a623010ac1c84 711 Pfam PF02743 Cache domain 48 330 5.0E-12 T 13-09-2016 IPR033479 Double Cache domain 1 THL1_RS03560 0210692001fbf9e8679120a6701d658d 137 Gene3D G3DSA:3.90.1170.10 23 134 1.7E-52 T 13-09-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 THL1_RS03560 0210692001fbf9e8679120a6701d658d 137 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 13-09-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03560 0210692001fbf9e8679120a6701d658d 137 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.3E-39 T 13-09-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 THL1_RS03560 0210692001fbf9e8679120a6701d658d 137 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.3E-39 T 13-09-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 THL1_RS03560 0210692001fbf9e8679120a6701d658d 137 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.3E-39 T 13-09-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 THL1_RS03560 0210692001fbf9e8679120a6701d658d 137 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.3E-39 T 13-09-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 THL1_RS03560 0210692001fbf9e8679120a6701d658d 137 PANTHER PTHR12220 1 137 5.7E-73 T 13-09-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 THL1_RS03560 0210692001fbf9e8679120a6701d658d 137 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 9.2E-48 T 13-09-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 THL1_RS03560 0210692001fbf9e8679120a6701d658d 137 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 4.3E-60 T 13-09-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 THL1_RS03560 0210692001fbf9e8679120a6701d658d 137 SUPERFAMILY SSF54686 1 134 3.53E-53 T 13-09-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 THL1_RS03560 0210692001fbf9e8679120a6701d658d 137 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 13-09-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03560 0210692001fbf9e8679120a6701d658d 137 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.091 T 13-09-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 THL1_RS28225 ecff9ce8cc5e2ec918bf79eb092089df 258 Gene3D G3DSA:3.30.450.40 84 255 7.2E-54 T 13-09-2016 IPR029016 GAF domain-like THL1_RS28225 ecff9ce8cc5e2ec918bf79eb092089df 258 SUPERFAMILY SSF46785 11 82 1.23E-16 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS28225 ecff9ce8cc5e2ec918bf79eb092089df 258 Pfam PF09339 IclR helix-turn-helix domain 12 59 8.8E-17 T 13-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 THL1_RS28225 ecff9ce8cc5e2ec918bf79eb092089df 258 PANTHER PTHR30136 11 252 1.1E-63 T 13-09-2016 THL1_RS28225 ecff9ce8cc5e2ec918bf79eb092089df 258 Gene3D G3DSA:1.10.10.10 5 81 7.2E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS28225 ecff9ce8cc5e2ec918bf79eb092089df 258 SUPERFAMILY SSF55781 76 253 2.03E-49 T 13-09-2016 IPR029016 GAF domain-like THL1_RS28225 ecff9ce8cc5e2ec918bf79eb092089df 258 Pfam PF01614 Bacterial transcriptional regulator 130 253 1.7E-33 T 13-09-2016 IPR014757 Transcription regulator IclR, C-terminal THL1_RS28225 ecff9ce8cc5e2ec918bf79eb092089df 258 SMART SM00346 10 100 2.6E-31 T 13-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 THL1_RS09075 98556cd0bfebcbb649511a349c80253f 137 SMART SM00347 24 123 2.1E-11 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS09075 98556cd0bfebcbb649511a349c80253f 137 PANTHER PTHR33164 5 134 9.6E-24 T 13-09-2016 THL1_RS09075 98556cd0bfebcbb649511a349c80253f 137 PANTHER PTHR33164:SF1 5 134 9.6E-24 T 13-09-2016 THL1_RS09075 98556cd0bfebcbb649511a349c80253f 137 SUPERFAMILY SSF46785 3 135 6.37E-31 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09075 98556cd0bfebcbb649511a349c80253f 137 Pfam PF13463 Winged helix DNA-binding domain 35 96 4.9E-8 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS09075 98556cd0bfebcbb649511a349c80253f 137 Gene3D G3DSA:1.10.10.10 4 134 8.4E-33 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS23025 fa5a314ae3dad9db11fa8b737c7c90f6 179 PIRSF PIRSF011484 1 177 4.4E-52 T 13-09-2016 IPR009822 YaeQ THL1_RS23025 fa5a314ae3dad9db11fa8b737c7c90f6 179 PANTHER PTHR38784:SF1 1 179 1.7E-88 T 13-09-2016 THL1_RS23025 fa5a314ae3dad9db11fa8b737c7c90f6 179 PANTHER PTHR38784 1 179 1.7E-88 T 13-09-2016 THL1_RS23025 fa5a314ae3dad9db11fa8b737c7c90f6 179 Pfam PF07152 YaeQ protein 1 170 1.9E-61 T 13-09-2016 IPR009822 YaeQ THL1_RS23025 fa5a314ae3dad9db11fa8b737c7c90f6 179 SMART SM01322 1 174 1.2E-90 T 13-09-2016 IPR009822 YaeQ THL1_RS23025 fa5a314ae3dad9db11fa8b737c7c90f6 179 SUPERFAMILY SSF52980 2 176 3.75E-61 T 13-09-2016 IPR011335 Restriction endonuclease type II-like THL1_RS23025 fa5a314ae3dad9db11fa8b737c7c90f6 179 Gene3D G3DSA:3.10.640.10 1 176 1.3E-65 T 13-09-2016 THL1_RS03045 6037b15e60e02b3a7b384af188bf9107 145 PANTHER PTHR30007 1 138 9.1E-32 T 13-09-2016 THL1_RS03045 6037b15e60e02b3a7b384af188bf9107 145 Pfam PF13586 Transposase DDE domain 49 137 4.0E-20 T 13-09-2016 IPR025668 Transposase DDE domain THL1_RS03045 6037b15e60e02b3a7b384af188bf9107 145 PANTHER PTHR30007:SF22 1 138 9.1E-32 T 13-09-2016 THL1_RS17935 05a44bedd240c8402641ac13a7ff41dc 615 PANTHER PTHR30290 1 361 4.7E-239 T 13-09-2016 THL1_RS17935 05a44bedd240c8402641ac13a7ff41dc 615 PANTHER PTHR30290:SF2 386 606 4.7E-239 T 13-09-2016 THL1_RS17935 05a44bedd240c8402641ac13a7ff41dc 615 PANTHER PTHR30290:SF2 1 361 4.7E-239 T 13-09-2016 THL1_RS17935 05a44bedd240c8402641ac13a7ff41dc 615 PANTHER PTHR30290 386 606 4.7E-239 T 13-09-2016 THL1_RS17935 05a44bedd240c8402641ac13a7ff41dc 615 Gene3D G3DSA:3.10.105.10 311 565 7.3E-48 T 13-09-2016 THL1_RS17935 05a44bedd240c8402641ac13a7ff41dc 615 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 105 510 2.2E-75 T 13-09-2016 IPR000914 Solute-binding protein family 5 domain THL1_RS17935 05a44bedd240c8402641ac13a7ff41dc 615 PIRSF PIRSF002741 9 597 8.0E-113 T 13-09-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 THL1_RS17935 05a44bedd240c8402641ac13a7ff41dc 615 SUPERFAMILY SSF53850 54 597 1.45E-126 T 13-09-2016 THL1_RS17935 05a44bedd240c8402641ac13a7ff41dc 615 Gene3D G3DSA:3.90.76.10 69 220 4.3E-35 T 13-09-2016 THL1_RS20035 061a17436748b9f7ecd811da5b32cc5a 224 Gene3D G3DSA:1.20.910.10 1 218 2.5E-17 T 13-09-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 THL1_RS20035 061a17436748b9f7ecd811da5b32cc5a 224 Pfam PF14518 Iron-containing redox enzyme 38 206 4.1E-26 T 13-09-2016 IPR028201 PqqC-like protein THL1_RS20035 061a17436748b9f7ecd811da5b32cc5a 224 SUPERFAMILY SSF48613 1 214 3.06E-62 T 13-09-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 THL1_RS20035 061a17436748b9f7ecd811da5b32cc5a 224 SMART SM01236 73 170 0.0019 T 13-09-2016 THL1_RS00170 26dd581ca605ce24b556f3ce0dec1e5e 402 SUPERFAMILY SSF53686 8 394 1.26E-151 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS00170 26dd581ca605ce24b556f3ce0dec1e5e 402 PANTHER PTHR10314:SF3 12 400 7.8E-244 T 13-09-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 THL1_RS00170 26dd581ca605ce24b556f3ce0dec1e5e 402 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 58 383 7.7E-47 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS00170 26dd581ca605ce24b556f3ce0dec1e5e 402 PIRSF PIRSF001413 4 402 1.6E-164 T 13-09-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 THL1_RS00170 26dd581ca605ce24b556f3ce0dec1e5e 402 PANTHER PTHR10314 12 400 7.8E-244 T 13-09-2016 THL1_RS00170 26dd581ca605ce24b556f3ce0dec1e5e 402 Gene3D G3DSA:3.40.50.1100 183 398 2.0E-98 T 13-09-2016 THL1_RS00170 26dd581ca605ce24b556f3ce0dec1e5e 402 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 86 100 - T 13-09-2016 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 THL1_RS00170 26dd581ca605ce24b556f3ce0dec1e5e 402 Gene3D G3DSA:3.40.50.1100 104 182 8.7E-22 T 13-09-2016 THL1_RS00170 26dd581ca605ce24b556f3ce0dec1e5e 402 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 12 395 1.5E-196 T 13-09-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 THL1_RS00170 26dd581ca605ce24b556f3ce0dec1e5e 402 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 7 396 52.592 T 13-09-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 THL1_RS07245 6f2debd423ea331105f2e2191dc48f2e 382 PANTHER PTHR24220:SF402 16 277 2.4E-135 T 13-09-2016 THL1_RS07245 6f2debd423ea331105f2e2191dc48f2e 382 PANTHER PTHR24220 16 277 2.4E-135 T 13-09-2016 THL1_RS07245 6f2debd423ea331105f2e2191dc48f2e 382 SUPERFAMILY SSF50331 249 366 2.72E-8 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS07245 6f2debd423ea331105f2e2191dc48f2e 382 PANTHER PTHR24220 312 323 2.4E-135 T 13-09-2016 THL1_RS07245 6f2debd423ea331105f2e2191dc48f2e 382 SMART SM00382 39 222 5.6E-15 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS07245 6f2debd423ea331105f2e2191dc48f2e 382 Gene3D G3DSA:3.40.50.300 8 247 5.7E-81 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07245 6f2debd423ea331105f2e2191dc48f2e 382 SUPERFAMILY SSF52540 14 253 7.92E-86 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07245 6f2debd423ea331105f2e2191dc48f2e 382 PANTHER PTHR24220:SF402 312 323 2.4E-135 T 13-09-2016 THL1_RS07245 6f2debd423ea331105f2e2191dc48f2e 382 Pfam PF08402 TOBE domain 284 365 1.6E-10 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS07245 6f2debd423ea331105f2e2191dc48f2e 382 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS07245 6f2debd423ea331105f2e2191dc48f2e 382 Pfam PF00005 ABC transporter 30 172 3.7E-35 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS21305 149bd3e550a1ae61c4d8e05d85b9b963 284 ProSitePatterns PS00761 Signal peptidases I signature 3. 221 234 - T 13-09-2016 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 THL1_RS21305 149bd3e550a1ae61c4d8e05d85b9b963 284 ProSitePatterns PS00501 Signal peptidases I serine active site. 88 95 - T 13-09-2016 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: REACT_15380 THL1_RS21305 149bd3e550a1ae61c4d8e05d85b9b963 284 PANTHER PTHR12383 3 271 3.5E-95 T 13-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 THL1_RS21305 149bd3e550a1ae61c4d8e05d85b9b963 284 SUPERFAMILY SSF51306 77 271 4.71E-65 T 13-09-2016 IPR015927 Peptidase S24/S26A/S26B/S26C THL1_RS21305 149bd3e550a1ae61c4d8e05d85b9b963 284 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 64 266 2.2E-48 T 13-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 THL1_RS21305 149bd3e550a1ae61c4d8e05d85b9b963 284 Pfam PF00717 Peptidase S24-like 85 167 1.4E-22 T 13-09-2016 IPR019759 Peptidase S24/S26A/S26B THL1_RS21305 149bd3e550a1ae61c4d8e05d85b9b963 284 ProSitePatterns PS00760 Signal peptidases I lysine active site. 145 157 - T 13-09-2016 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 THL1_RS21305 149bd3e550a1ae61c4d8e05d85b9b963 284 PANTHER PTHR12383:SF27 3 271 3.5E-95 T 13-09-2016 THL1_RS21305 149bd3e550a1ae61c4d8e05d85b9b963 284 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 216 235 8.6E-26 T 13-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 THL1_RS21305 149bd3e550a1ae61c4d8e05d85b9b963 284 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 143 155 8.6E-26 T 13-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 THL1_RS21305 149bd3e550a1ae61c4d8e05d85b9b963 284 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 79 95 8.6E-26 T 13-09-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 THL1_RS21305 149bd3e550a1ae61c4d8e05d85b9b963 284 Gene3D G3DSA:2.10.109.10 75 153 1.6E-54 T 13-09-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain THL1_RS21305 149bd3e550a1ae61c4d8e05d85b9b963 284 Gene3D G3DSA:2.10.109.10 216 268 1.6E-54 T 13-09-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain THL1_RS11425 3f6f7e5c701df89e8c66bc953963079c 567 Gene3D G3DSA:3.30.300.30 445 546 6.7E-24 T 13-09-2016 THL1_RS11425 3f6f7e5c701df89e8c66bc953963079c 567 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 533 7.1E-18 T 13-09-2016 IPR025110 AMP-binding enzyme C-terminal domain THL1_RS11425 3f6f7e5c701df89e8c66bc953963079c 567 Gene3D G3DSA:2.30.38.10 366 440 1.4E-17 T 13-09-2016 THL1_RS11425 3f6f7e5c701df89e8c66bc953963079c 567 Pfam PF00501 AMP-binding enzyme 49 446 6.3E-72 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS11425 3f6f7e5c701df89e8c66bc953963079c 567 PANTHER PTHR24095 20 548 5.2E-195 T 13-09-2016 THL1_RS11425 3f6f7e5c701df89e8c66bc953963079c 567 SUPERFAMILY SSF56801 18 543 3.53E-130 T 13-09-2016 THL1_RS11425 3f6f7e5c701df89e8c66bc953963079c 567 ProSitePatterns PS00455 Putative AMP-binding domain signature. 199 210 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS11425 3f6f7e5c701df89e8c66bc953963079c 567 Gene3D G3DSA:3.40.50.980 48 205 3.5E-29 T 13-09-2016 THL1_RS11425 3f6f7e5c701df89e8c66bc953963079c 567 PANTHER PTHR24095:SF180 20 548 5.2E-195 T 13-09-2016 THL1_RS11425 3f6f7e5c701df89e8c66bc953963079c 567 Gene3D G3DSA:3.40.50.980 206 365 1.8E-26 T 13-09-2016 THL1_RS09260 6aa636533334d608464eaa13b683c7cb 361 Pfam PF13416 Bacterial extracellular solute-binding protein 38 326 4.6E-35 T 13-09-2016 THL1_RS09260 6aa636533334d608464eaa13b683c7cb 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 86 99 3.9E-65 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09260 6aa636533334d608464eaa13b683c7cb 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 260 279 3.9E-65 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09260 6aa636533334d608464eaa13b683c7cb 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 27 43 3.9E-65 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09260 6aa636533334d608464eaa13b683c7cb 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 119 135 3.9E-65 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09260 6aa636533334d608464eaa13b683c7cb 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 43 64 3.9E-65 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09260 6aa636533334d608464eaa13b683c7cb 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 70 84 3.9E-65 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09260 6aa636533334d608464eaa13b683c7cb 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 305 331 3.9E-65 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09260 6aa636533334d608464eaa13b683c7cb 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 210 229 3.9E-65 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09260 6aa636533334d608464eaa13b683c7cb 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 150 164 3.9E-65 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09260 6aa636533334d608464eaa13b683c7cb 361 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 173 192 3.9E-65 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09260 6aa636533334d608464eaa13b683c7cb 361 PANTHER PTHR30222:SF11 5 360 2.3E-181 T 13-09-2016 THL1_RS09260 6aa636533334d608464eaa13b683c7cb 361 PIRSF PIRSF019574 3 361 2.2E-135 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS09260 6aa636533334d608464eaa13b683c7cb 361 PANTHER PTHR30222 5 360 2.3E-181 T 13-09-2016 THL1_RS09260 6aa636533334d608464eaa13b683c7cb 361 Gene3D G3DSA:3.40.190.10 142 310 1.6E-70 T 13-09-2016 THL1_RS09260 6aa636533334d608464eaa13b683c7cb 361 SUPERFAMILY SSF53850 22 360 4.03E-102 T 13-09-2016 THL1_RS09260 6aa636533334d608464eaa13b683c7cb 361 Gene3D G3DSA:3.40.190.10 38 141 6.2E-13 T 13-09-2016 THL1_RS22505 eb7b863e82938a94f41e163e88ef4045 352 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 6 342 27.52 T 13-09-2016 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS22505 eb7b863e82938a94f41e163e88ef4045 352 PANTHER PTHR13326 21 340 1.1E-60 T 13-09-2016 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS22505 eb7b863e82938a94f41e163e88ef4045 352 SUPERFAMILY SSF55120 9 339 8.63E-95 T 13-09-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS22505 eb7b863e82938a94f41e163e88ef4045 352 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 78 91 - T 13-09-2016 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS22505 eb7b863e82938a94f41e163e88ef4045 352 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 188 337 5.8E-18 T 13-09-2016 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS22505 eb7b863e82938a94f41e163e88ef4045 352 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 19 169 8.0E-39 T 13-09-2016 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS21035 22db7c47930779736a3caca4917fb079 256 PANTHER PTHR31126 111 255 1.0E-47 T 13-09-2016 THL1_RS21035 22db7c47930779736a3caca4917fb079 256 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 144 154 - T 13-09-2016 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311|GO:0016791 THL1_RS21035 22db7c47930779736a3caca4917fb079 256 PANTHER PTHR31126:SF21 111 255 1.0E-47 T 13-09-2016 THL1_RS21035 22db7c47930779736a3caca4917fb079 256 Gene3D G3DSA:3.90.190.10 11 179 4.4E-19 T 13-09-2016 IPR029021 Protein-tyrosine phosphatase-like THL1_RS21035 22db7c47930779736a3caca4917fb079 256 PANTHER PTHR31126 13 86 1.0E-47 T 13-09-2016 THL1_RS21035 22db7c47930779736a3caca4917fb079 256 PANTHER PTHR31126:SF21 13 86 1.0E-47 T 13-09-2016 THL1_RS21035 22db7c47930779736a3caca4917fb079 256 SUPERFAMILY SSF52799 10 255 4.77E-49 T 13-09-2016 IPR029021 Protein-tyrosine phosphatase-like THL1_RS21035 22db7c47930779736a3caca4917fb079 256 Pfam PF13350 Tyrosine phosphatase family 8 255 1.2E-60 T 13-09-2016 IPR026893 Tyrosine/serine-protein phosphatase IphP-type THL1_RS10760 184bd9c9652eccfcc5eb5d48964092d7 414 Pfam PF02687 FtsX-like permease family 274 407 1.2E-21 T 13-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 THL1_RS10760 184bd9c9652eccfcc5eb5d48964092d7 414 Pfam PF12704 MacB-like periplasmic core domain 27 242 1.3E-20 T 13-09-2016 IPR025857 MacB-like periplasmic core domain THL1_RS10760 184bd9c9652eccfcc5eb5d48964092d7 414 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 4 414 2.1E-153 T 13-09-2016 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 THL1_RS10760 184bd9c9652eccfcc5eb5d48964092d7 414 PANTHER PTHR30489:SF8 1 414 2.5E-115 T 13-09-2016 THL1_RS10760 184bd9c9652eccfcc5eb5d48964092d7 414 PANTHER PTHR30489 1 414 2.5E-115 T 13-09-2016 THL1_RS00620 e6cd83669c8e6c020d35a33ffe656720 425 Gene3D G3DSA:3.90.1150.10 304 425 1.6E-44 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS00620 e6cd83669c8e6c020d35a33ffe656720 425 PANTHER PTHR11986:SF70 1 424 0.0 T 13-09-2016 THL1_RS00620 e6cd83669c8e6c020d35a33ffe656720 425 PANTHER PTHR11986 1 424 0.0 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS00620 e6cd83669c8e6c020d35a33ffe656720 425 SUPERFAMILY SSF53383 18 424 7.98E-141 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS00620 e6cd83669c8e6c020d35a33ffe656720 425 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 273 - T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS00620 e6cd83669c8e6c020d35a33ffe656720 425 Pfam PF00202 Aminotransferase class-III 15 420 9.5E-137 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS00620 e6cd83669c8e6c020d35a33ffe656720 425 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 9 420 3.2E-162 T 13-09-2016 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 THL1_RS00620 e6cd83669c8e6c020d35a33ffe656720 425 Gene3D G3DSA:3.40.640.10 59 303 8.6E-88 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS19730 fdb1ac1e4b9dab593e9c8254d7d907a8 545 PANTHER PTHR24220 11 404 1.0E-106 T 13-09-2016 THL1_RS19730 fdb1ac1e4b9dab593e9c8254d7d907a8 545 Pfam PF00005 ABC transporter 30 187 2.5E-22 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS19730 fdb1ac1e4b9dab593e9c8254d7d907a8 545 Pfam PF00005 ABC transporter 295 448 3.8E-29 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS19730 fdb1ac1e4b9dab593e9c8254d7d907a8 545 SUPERFAMILY SSF52540 7 261 1.16E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS19730 fdb1ac1e4b9dab593e9c8254d7d907a8 545 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 501 534 0.0022 T 13-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THL1_RS19730 fdb1ac1e4b9dab593e9c8254d7d907a8 545 PANTHER PTHR24220:SF574 11 404 1.0E-106 T 13-09-2016 THL1_RS19730 fdb1ac1e4b9dab593e9c8254d7d907a8 545 Gene3D G3DSA:3.40.50.300 274 527 4.5E-71 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS19730 fdb1ac1e4b9dab593e9c8254d7d907a8 545 SUPERFAMILY SSF52540 279 517 2.01E-61 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS19730 fdb1ac1e4b9dab593e9c8254d7d907a8 545 SMART SM00382 38 237 2.4E-14 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS19730 fdb1ac1e4b9dab593e9c8254d7d907a8 545 SMART SM00382 304 497 5.5E-17 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS19730 fdb1ac1e4b9dab593e9c8254d7d907a8 545 ProSitePatterns PS00211 ABC transporters family signature. 420 434 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS19730 fdb1ac1e4b9dab593e9c8254d7d907a8 545 Gene3D G3DSA:3.40.50.300 8 259 5.4E-62 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15290 d23f90cdc3f576c234ec522d704ddefb 288 Gene3D G3DSA:3.30.420.10 118 277 5.0E-39 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS15290 d23f90cdc3f576c234ec522d704ddefb 288 Pfam PF13276 HTH-like domain 44 99 3.9E-15 T 13-09-2016 IPR025948 HTH-like domain THL1_RS15290 d23f90cdc3f576c234ec522d704ddefb 288 SUPERFAMILY SSF53098 117 283 3.19E-43 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS15290 d23f90cdc3f576c234ec522d704ddefb 288 Pfam PF00665 Integrase core domain 125 238 1.1E-32 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS15290 d23f90cdc3f576c234ec522d704ddefb 288 PANTHER PTHR32552 5 282 6.4E-75 T 13-09-2016 THL1_RS07435 c724a4ef0ce84e06957af80618a94117 197 SMART SM00530 18 73 1.5E-13 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS07435 c724a4ef0ce84e06957af80618a94117 197 SUPERFAMILY SSF47413 13 80 1.64E-15 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS07435 c724a4ef0ce84e06957af80618a94117 197 Pfam PF07883 Cupin domain 130 191 7.7E-11 T 13-09-2016 IPR013096 Cupin 2, conserved barrel THL1_RS07435 c724a4ef0ce84e06957af80618a94117 197 SUPERFAMILY SSF51182 79 192 1.57E-24 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS07435 c724a4ef0ce84e06957af80618a94117 197 Gene3D G3DSA:2.60.120.10 103 195 7.0E-24 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS07435 c724a4ef0ce84e06957af80618a94117 197 Gene3D G3DSA:1.10.260.40 12 79 2.3E-18 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS07435 c724a4ef0ce84e06957af80618a94117 197 PANTHER PTHR10245 10 176 1.3E-27 T 13-09-2016 THL1_RS07435 c724a4ef0ce84e06957af80618a94117 197 PANTHER PTHR10245:SF9 10 176 1.3E-27 T 13-09-2016 THL1_RS07435 c724a4ef0ce84e06957af80618a94117 197 Pfam PF01381 Helix-turn-helix 19 72 1.2E-11 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS25130 ad3c335bd33eac8211d682596c044e83 297 Gene3D G3DSA:3.40.190.10 92 176 6.3E-24 T 13-09-2016 THL1_RS25130 ad3c335bd33eac8211d682596c044e83 297 PANTHER PTHR30537:SF30 1 297 3.3E-150 T 13-09-2016 THL1_RS25130 ad3c335bd33eac8211d682596c044e83 297 Pfam PF03466 LysR substrate binding domain 88 291 9.0E-42 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS25130 ad3c335bd33eac8211d682596c044e83 297 Gene3D G3DSA:3.40.190.10 177 261 2.6E-19 T 13-09-2016 THL1_RS25130 ad3c335bd33eac8211d682596c044e83 297 Gene3D G3DSA:1.10.10.10 3 87 3.8E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS25130 ad3c335bd33eac8211d682596c044e83 297 SUPERFAMILY SSF46785 4 112 9.35E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS25130 ad3c335bd33eac8211d682596c044e83 297 SUPERFAMILY SSF53850 90 295 4.16E-43 T 13-09-2016 THL1_RS25130 ad3c335bd33eac8211d682596c044e83 297 PANTHER PTHR30537 1 297 3.3E-150 T 13-09-2016 THL1_RS25130 ad3c335bd33eac8211d682596c044e83 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.3E-19 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 13-09-2016 IPR006074 GTP1/OBG, conserved site GO:0005525 THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 Pfam PF01018 GTP1/OBG 3 158 1.3E-61 T 13-09-2016 IPR006169 GTP1/OBG domain GO:0005525 THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 SUPERFAMILY SSF52540 151 338 4.74E-48 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 PANTHER PTHR11702 372 395 6.8E-177 T 13-09-2016 THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 PANTHER PTHR11702 1 355 6.8E-177 T 13-09-2016 THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 Pfam PF01926 50S ribosome-binding GTPase 161 284 1.3E-21 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 PIRSF PIRSF002401 1 379 6.1E-138 T 13-09-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 Gene3D G3DSA:2.70.210.12 2 155 2.3E-59 T 13-09-2016 IPR006169 GTP1/OBG domain GO:0005525 THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 Hamap MF_01454 GTPase Obg [obg]. 2 333 47.362 T 13-09-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 Gene3D G3DSA:3.40.50.300 156 342 4.0E-47 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 PANTHER PTHR11702:SF3 372 395 6.8E-177 T 13-09-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 PANTHER PTHR11702:SF3 1 355 6.8E-177 T 13-09-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 332 7.0E-144 T 13-09-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 6.7E-34 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 6.7E-34 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 6.7E-34 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 6.7E-34 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS04830 aa3468928ba34912d635a8c37e8c296f 405 SUPERFAMILY SSF82051 2 158 8.5E-57 T 13-09-2016 IPR006169 GTP1/OBG domain GO:0005525 THL1_RS05175 0ef549d0579cee88481fb51b583a0b2d 368 PIRSF PIRSF000138 7 368 7.1E-124 T 13-09-2016 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 THL1_RS05175 0ef549d0579cee88481fb51b583a0b2d 368 PANTHER PTHR10578 1 368 5.3E-146 T 13-09-2016 THL1_RS05175 0ef549d0579cee88481fb51b583a0b2d 368 Pfam PF01070 FMN-dependent dehydrogenase 25 367 1.7E-126 T 13-09-2016 IPR000262 FMN-dependent dehydrogenase GO:0016491 THL1_RS05175 0ef549d0579cee88481fb51b583a0b2d 368 SUPERFAMILY SSF51395 15 366 1.04E-96 T 13-09-2016 THL1_RS05175 0ef549d0579cee88481fb51b583a0b2d 368 Gene3D G3DSA:3.20.20.70 15 367 8.8E-133 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS18955 8a779485465c138e1bad6f37f87b613c 302 SUPERFAMILY SSF53850 7 272 1.71E-61 T 13-09-2016 THL1_RS18955 8a779485465c138e1bad6f37f87b613c 302 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 269 7.0E-47 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS18955 8a779485465c138e1bad6f37f87b613c 302 SMART SM00062 38 271 1.0E-46 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS18955 8a779485465c138e1bad6f37f87b613c 302 Gene3D G3DSA:3.40.190.10 125 231 8.0E-28 T 13-09-2016 THL1_RS18955 8a779485465c138e1bad6f37f87b613c 302 PANTHER PTHR30085 6 302 4.1E-137 T 13-09-2016 THL1_RS18955 8a779485465c138e1bad6f37f87b613c 302 PANTHER PTHR30085:SF2 6 302 4.1E-137 T 13-09-2016 THL1_RS18955 8a779485465c138e1bad6f37f87b613c 302 Gene3D G3DSA:3.40.190.10 232 273 3.7E-24 T 13-09-2016 THL1_RS18955 8a779485465c138e1bad6f37f87b613c 302 Gene3D G3DSA:3.40.190.10 35 124 3.7E-24 T 13-09-2016 THL1_RS15470 0325b0a8ac3924965d1adc2615219607 442 Pfam PF01523 Putative modulator of DNA gyrase 27 300 1.6E-15 T 13-09-2016 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS15470 0325b0a8ac3924965d1adc2615219607 442 PANTHER PTHR30624 1 441 5.9E-94 T 13-09-2016 THL1_RS15470 0325b0a8ac3924965d1adc2615219607 442 PANTHER PTHR30624:SF8 1 441 5.9E-94 T 13-09-2016 THL1_RS15470 0325b0a8ac3924965d1adc2615219607 442 SUPERFAMILY SSF111283 15 440 1.96E-59 T 13-09-2016 THL1_RS16625 f829e8b9aac07b4a6d7d9617e9edc0e9 716 ProSitePatterns PS00211 ABC transporters family signature. 612 626 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS16625 f829e8b9aac07b4a6d7d9617e9edc0e9 716 Pfam PF03412 Peptidase C39 family 11 134 1.3E-22 T 13-09-2016 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 THL1_RS16625 f829e8b9aac07b4a6d7d9617e9edc0e9 716 SUPERFAMILY SSF52540 466 711 1.02E-88 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16625 f829e8b9aac07b4a6d7d9617e9edc0e9 716 Pfam PF00005 ABC transporter 491 640 1.8E-34 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS16625 f829e8b9aac07b4a6d7d9617e9edc0e9 716 Pfam PF00664 ABC transporter transmembrane region 162 426 2.2E-55 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS16625 f829e8b9aac07b4a6d7d9617e9edc0e9 716 SMART SM00382 500 686 3.0E-18 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS16625 f829e8b9aac07b4a6d7d9617e9edc0e9 716 TIGRFAM TIGR01846 type_I_sec_HlyB: type I secretion system ATPase 17 712 0.0 T 13-09-2016 IPR010132 ATPase, type I secretion system, HlyB GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 THL1_RS16625 f829e8b9aac07b4a6d7d9617e9edc0e9 716 Gene3D G3DSA:3.40.50.300 473 704 2.7E-83 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16625 f829e8b9aac07b4a6d7d9617e9edc0e9 716 PANTHER PTHR24221:SF246 142 713 0.0 T 13-09-2016 THL1_RS16625 f829e8b9aac07b4a6d7d9617e9edc0e9 716 PANTHER PTHR24221 142 713 0.0 T 13-09-2016 THL1_RS16625 f829e8b9aac07b4a6d7d9617e9edc0e9 716 SUPERFAMILY SSF90123 147 454 4.32E-69 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS16625 f829e8b9aac07b4a6d7d9617e9edc0e9 716 Gene3D G3DSA:1.20.1560.10 147 454 1.3E-82 T 13-09-2016 THL1_RS16625 f829e8b9aac07b4a6d7d9617e9edc0e9 716 Gene3D G3DSA:3.90.70.10 12 134 1.3E-37 T 13-09-2016 THL1_RS05350 b3eb045ab24126722886f97ee1024cad 285 PIRSF PIRSF005052 1 285 1.3E-113 T 13-09-2016 IPR005337 RapZ-like family GO:0005524 THL1_RS05350 b3eb045ab24126722886f97ee1024cad 285 PANTHER PTHR30448 1 284 1.2E-133 T 13-09-2016 THL1_RS05350 b3eb045ab24126722886f97ee1024cad 285 SUPERFAMILY SSF52540 1 154 2.19E-13 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05350 b3eb045ab24126722886f97ee1024cad 285 Gene3D G3DSA:3.40.50.300 1 154 4.2E-15 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05350 b3eb045ab24126722886f97ee1024cad 285 PANTHER PTHR30448:SF0 1 284 1.2E-133 T 13-09-2016 THL1_RS05350 b3eb045ab24126722886f97ee1024cad 285 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 285 39.028 T 13-09-2016 IPR005337 RapZ-like family GO:0005524 THL1_RS05350 b3eb045ab24126722886f97ee1024cad 285 Pfam PF03668 P-loop ATPase protein family 1 284 1.5E-93 T 13-09-2016 IPR005337 RapZ-like family GO:0005524 THL1_RS19375 1f0cf801fb86776bfbf908a9c9a6c935 451 Pfam PF13520 Amino acid permease 12 418 8.1E-38 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS19375 1f0cf801fb86776bfbf908a9c9a6c935 451 PIRSF PIRSF006060 2 450 2.8E-56 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS19375 1f0cf801fb86776bfbf908a9c9a6c935 451 PANTHER PTHR11785 8 438 9.5E-83 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS19375 1f0cf801fb86776bfbf908a9c9a6c935 451 PANTHER PTHR11785:SF261 8 438 9.5E-83 T 13-09-2016 THL1_RS18295 ba08ddf637f4f3e5b40fff100e925cad 182 SUPERFAMILY SSF55620 3 181 2.22E-78 T 13-09-2016 THL1_RS18295 ba08ddf637f4f3e5b40fff100e925cad 182 Pfam PF01227 GTP cyclohydrolase I 4 180 6.3E-76 T 13-09-2016 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 THL1_RS18295 ba08ddf637f4f3e5b40fff100e925cad 182 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 4 181 3.1E-77 T 13-09-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 THL1_RS18295 ba08ddf637f4f3e5b40fff100e925cad 182 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 60 76 - T 13-09-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 THL1_RS18295 ba08ddf637f4f3e5b40fff100e925cad 182 Gene3D G3DSA:3.30.1130.10 53 181 2.1E-63 T 13-09-2016 THL1_RS18295 ba08ddf637f4f3e5b40fff100e925cad 182 PANTHER PTHR11109 2 182 1.4E-114 T 13-09-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 THL1_RS18295 ba08ddf637f4f3e5b40fff100e925cad 182 Gene3D G3DSA:1.10.286.10 3 50 1.1E-20 T 13-09-2016 THL1_RS18295 ba08ddf637f4f3e5b40fff100e925cad 182 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 1 181 36.758 T 13-09-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 THL1_RS18295 ba08ddf637f4f3e5b40fff100e925cad 182 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 108 118 - T 13-09-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 1.7E-8 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 472 1.7E-8 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 453 1.7E-8 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 PANTHER PTHR22617:SF6 6 622 1.2E-129 T 13-09-2016 THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 SUPERFAMILY SSF52172 632 752 8.97E-32 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 SMART SM00387 332 475 2.4E-19 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 SMART SM00448 634 748 3.0E-32 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 PANTHER PTHR22617 6 622 1.2E-129 T 13-09-2016 THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 SUPERFAMILY SSF55874 291 473 1.06E-34 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 Gene3D G3DSA:3.30.565.10 293 474 4.1E-30 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 Pfam PF01627 Hpt domain 11 97 2.6E-16 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 Pfam PF00072 Response regulator receiver domain 636 748 6.5E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 SMART SM00260 467 606 6.4E-12 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 335 474 7.8E-12 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 Gene3D G3DSA:3.40.50.2300 632 752 4.2E-33 T 13-09-2016 THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 Pfam PF01584 CheW-like domain 481 609 2.5E-18 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 SMART SM00073 8 105 7.4E-16 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 SUPERFAMILY SSF47226 8 128 1.11E-24 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 Gene3D G3DSA:1.20.120.160 6 135 3.8E-32 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 Gene3D G3DSA:2.30.30.40 475 496 1.2E-12 T 13-09-2016 THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 Gene3D G3DSA:2.30.30.40 561 606 1.2E-12 T 13-09-2016 THL1_RS22900 8491dde553848a9e57f4c916a8ee3983 757 SUPERFAMILY SSF50341 474 606 4.05E-24 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS07635 01a5be3b9a9942a3460e01f69ada4887 212 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 128 141 - T 13-09-2016 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 THL1_RS07635 01a5be3b9a9942a3460e01f69ada4887 212 PANTHER PTHR30246:SF0 1 212 4.0E-104 T 13-09-2016 THL1_RS07635 01a5be3b9a9942a3460e01f69ada4887 212 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 12 209 1.5E-77 T 13-09-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 THL1_RS07635 01a5be3b9a9942a3460e01f69ada4887 212 SUPERFAMILY SSF51569 13 210 8.61E-64 T 13-09-2016 THL1_RS07635 01a5be3b9a9942a3460e01f69ada4887 212 Pfam PF01081 KDPG and KHG aldolase 10 202 1.4E-83 T 13-09-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 THL1_RS07635 01a5be3b9a9942a3460e01f69ada4887 212 Gene3D G3DSA:3.20.20.70 13 211 4.0E-69 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS07635 01a5be3b9a9942a3460e01f69ada4887 212 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 40 49 - T 13-09-2016 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562|UniPathway: UPA00227|UniPathway: UPA00856 THL1_RS07635 01a5be3b9a9942a3460e01f69ada4887 212 PANTHER PTHR30246 1 212 4.0E-104 T 13-09-2016 THL1_RS16745 c2beaec43831f6c344af672440121cdd 440 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 333 437 7.3E-15 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS16745 c2beaec43831f6c344af672440121cdd 440 Gene3D G3DSA:3.30.565.10 311 439 9.8E-28 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS16745 c2beaec43831f6c344af672440121cdd 440 SMART SM00387 332 438 1.1E-22 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS16745 c2beaec43831f6c344af672440121cdd 440 SUPERFAMILY SSF47384 212 280 2.75E-5 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS16745 c2beaec43831f6c344af672440121cdd 440 PANTHER PTHR24423 171 435 3.3E-79 T 13-09-2016 THL1_RS16745 c2beaec43831f6c344af672440121cdd 440 SUPERFAMILY SSF55874 299 435 1.7E-27 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS16745 c2beaec43831f6c344af672440121cdd 440 PANTHER PTHR24423 30 61 3.3E-79 T 13-09-2016 THL1_RS16745 c2beaec43831f6c344af672440121cdd 440 PANTHER PTHR24423:SF543 30 61 3.3E-79 T 13-09-2016 THL1_RS16745 c2beaec43831f6c344af672440121cdd 440 PANTHER PTHR24423:SF543 171 435 3.3E-79 T 13-09-2016 THL1_RS16745 c2beaec43831f6c344af672440121cdd 440 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 381 1.2E-8 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS16745 c2beaec43831f6c344af672440121cdd 440 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 435 1.2E-8 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS16745 c2beaec43831f6c344af672440121cdd 440 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 416 1.2E-8 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS03720 f0662ec3135e83d4ac3c7d97babf4e7a 365 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 12 361 28.058 T 13-09-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 THL1_RS03720 f0662ec3135e83d4ac3c7d97babf4e7a 365 Pfam PF01888 CbiD 12 271 1.0E-91 T 13-09-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 THL1_RS03720 f0662ec3135e83d4ac3c7d97babf4e7a 365 SUPERFAMILY SSF111342 6 289 4.84E-84 T 13-09-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 THL1_RS03720 f0662ec3135e83d4ac3c7d97babf4e7a 365 PANTHER PTHR35863 1 360 3.4E-117 T 13-09-2016 THL1_RS03720 f0662ec3135e83d4ac3c7d97babf4e7a 365 Gene3D G3DSA:3.30.2110.10 14 186 4.8E-58 T 13-09-2016 THL1_RS03720 f0662ec3135e83d4ac3c7d97babf4e7a 365 PANTHER PTHR35863:SF1 1 360 3.4E-117 T 13-09-2016 THL1_RS03720 f0662ec3135e83d4ac3c7d97babf4e7a 365 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 19 320 1.5E-62 T 13-09-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 THL1_RS03720 f0662ec3135e83d4ac3c7d97babf4e7a 365 PIRSF PIRSF026782 9 365 5.1E-125 T 13-09-2016 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.195|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 THL1_RS02140 401d887bf71e13e9e0fb2b9576838f0d 295 Pfam PF00892 EamA-like transporter family 8 141 1.4E-16 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS02140 401d887bf71e13e9e0fb2b9576838f0d 295 TIGRFAM TIGR00688 rarD: protein RarD 8 260 1.8E-76 T 13-09-2016 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 THL1_RS02140 401d887bf71e13e9e0fb2b9576838f0d 295 PANTHER PTHR22911 1 295 5.1E-135 T 13-09-2016 THL1_RS02140 401d887bf71e13e9e0fb2b9576838f0d 295 PANTHER PTHR22911:SF41 1 295 5.1E-135 T 13-09-2016 THL1_RS02140 401d887bf71e13e9e0fb2b9576838f0d 295 SUPERFAMILY SSF103481 47 145 7.19E-14 T 13-09-2016 THL1_RS02140 401d887bf71e13e9e0fb2b9576838f0d 295 SUPERFAMILY SSF103481 189 285 2.88E-11 T 13-09-2016 THL1_RS27715 74ff4487f1816a6cf7e58105dee94d11 305 SUPERFAMILY SSF46785 3 86 4.9E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS27715 74ff4487f1816a6cf7e58105dee94d11 305 Gene3D G3DSA:3.40.190.10 93 178 1.6E-18 T 13-09-2016 THL1_RS27715 74ff4487f1816a6cf7e58105dee94d11 305 SUPERFAMILY SSF53850 93 296 3.26E-26 T 13-09-2016 THL1_RS27715 74ff4487f1816a6cf7e58105dee94d11 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 2.0E-21 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS27715 74ff4487f1816a6cf7e58105dee94d11 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 5.5E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS27715 74ff4487f1816a6cf7e58105dee94d11 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 5.5E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS27715 74ff4487f1816a6cf7e58105dee94d11 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 5.5E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS27715 74ff4487f1816a6cf7e58105dee94d11 305 Pfam PF03466 LysR substrate binding domain 92 293 1.8E-28 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS27715 74ff4487f1816a6cf7e58105dee94d11 305 Gene3D G3DSA:3.40.190.10 179 262 8.6E-15 T 13-09-2016 THL1_RS27715 74ff4487f1816a6cf7e58105dee94d11 305 PANTHER PTHR30537 1 297 7.6E-105 T 13-09-2016 THL1_RS27715 74ff4487f1816a6cf7e58105dee94d11 305 Gene3D G3DSA:1.10.10.10 1 86 3.4E-27 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS27715 74ff4487f1816a6cf7e58105dee94d11 305 PANTHER PTHR30537:SF26 1 297 7.6E-105 T 13-09-2016 THL1_RS18355 d89e8b5e67d5610827c781fa0d38f6a7 157 PANTHER PTHR42641 1 156 1.9E-86 T 13-09-2016 THL1_RS18355 d89e8b5e67d5610827c781fa0d38f6a7 157 Pfam PF05232 Chlorhexidine efflux transporter 79 142 2.3E-24 T 13-09-2016 IPR007896 Chlorhexidine efflux transporter THL1_RS18355 d89e8b5e67d5610827c781fa0d38f6a7 157 Pfam PF05232 Chlorhexidine efflux transporter 11 73 2.9E-25 T 13-09-2016 IPR007896 Chlorhexidine efflux transporter THL1_RS18355 d89e8b5e67d5610827c781fa0d38f6a7 157 PANTHER PTHR42641:SF2 1 156 1.9E-86 T 13-09-2016 THL1_RS11705 565aa0a86cf8a3c030e360988ad54e52 265 Gene3D G3DSA:3.10.129.10 130 262 1.5E-9 T 13-09-2016 IPR029069 HotDog domain THL1_RS11705 565aa0a86cf8a3c030e360988ad54e52 265 Gene3D G3DSA:3.10.129.10 2 109 6.3E-19 T 13-09-2016 IPR029069 HotDog domain THL1_RS11705 565aa0a86cf8a3c030e360988ad54e52 265 SUPERFAMILY SSF54637 117 263 7.9E-30 T 13-09-2016 IPR029069 HotDog domain THL1_RS11705 565aa0a86cf8a3c030e360988ad54e52 265 SUPERFAMILY SSF54637 1 108 3.32E-24 T 13-09-2016 IPR029069 HotDog domain THL1_RS11705 565aa0a86cf8a3c030e360988ad54e52 265 Pfam PF13622 Thioesterase-like superfamily 20 263 2.3E-50 T 13-09-2016 THL1_RS11705 565aa0a86cf8a3c030e360988ad54e52 265 PANTHER PTHR11066 19 255 2.2E-19 T 13-09-2016 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 THL1_RS20840 6a41b8dcdf615e3670fb68b40ea767db 890 SUPERFAMILY SSF52540 18 232 1.88E-7 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS20840 6a41b8dcdf615e3670fb68b40ea767db 890 Gene3D G3DSA:3.40.50.300 41 139 5.2E-5 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS20840 6a41b8dcdf615e3670fb68b40ea767db 890 Gene3D G3DSA:1.10.10.10 825 888 2.2E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20840 6a41b8dcdf615e3670fb68b40ea767db 890 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 859 871 1.9E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS20840 6a41b8dcdf615e3670fb68b40ea767db 890 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 829 843 1.9E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS20840 6a41b8dcdf615e3670fb68b40ea767db 890 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 843 859 1.9E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS20840 6a41b8dcdf615e3670fb68b40ea767db 890 Gene3D G3DSA:1.25.40.10 449 799 1.1E-24 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS20840 6a41b8dcdf615e3670fb68b40ea767db 890 Pfam PF00196 Bacterial regulatory proteins, luxR family 827 883 4.1E-16 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS20840 6a41b8dcdf615e3670fb68b40ea767db 890 SUPERFAMILY SSF46894 822 889 1.73E-18 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS20840 6a41b8dcdf615e3670fb68b40ea767db 890 SUPERFAMILY SSF48452 735 771 2.4E-9 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS20840 6a41b8dcdf615e3670fb68b40ea767db 890 SUPERFAMILY SSF48452 568 682 2.4E-9 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS20840 6a41b8dcdf615e3670fb68b40ea767db 890 SMART SM00421 826 883 2.5E-19 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS26380 72c6ed058b79bbcf1f2ca43433519ee7 124 PANTHER PTHR35303:SF1 1 124 1.1E-71 T 13-09-2016 THL1_RS26380 72c6ed058b79bbcf1f2ca43433519ee7 124 PANTHER PTHR35303 1 124 1.1E-71 T 13-09-2016 THL1_RS26380 72c6ed058b79bbcf1f2ca43433519ee7 124 Pfam PF06155 Protein of unknown function (DUF971) 7 89 5.2E-26 T 13-09-2016 IPR010376 Domain of unknown function DUF971 Reactome: REACT_13|UniPathway: UPA00118 THL1_RS05550 239854a3c63fd949be010b15efbe2d9a 260 Gene3D G3DSA:1.10.760.10 21 225 6.2E-58 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS05550 239854a3c63fd949be010b15efbe2d9a 260 PANTHER PTHR10266 203 260 1.4E-61 T 13-09-2016 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 THL1_RS05550 239854a3c63fd949be010b15efbe2d9a 260 PANTHER PTHR10266 7 163 1.4E-61 T 13-09-2016 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 THL1_RS05550 239854a3c63fd949be010b15efbe2d9a 260 Gene3D G3DSA:1.20.5.100 231 260 9.5E-8 T 13-09-2016 THL1_RS05550 239854a3c63fd949be010b15efbe2d9a 260 Pfam PF02167 Cytochrome C1 family 88 259 1.1E-9 T 13-09-2016 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 THL1_RS05550 239854a3c63fd949be010b15efbe2d9a 260 PANTHER PTHR10266:SF3 203 260 1.4E-61 T 13-09-2016 THL1_RS05550 239854a3c63fd949be010b15efbe2d9a 260 PANTHER PTHR10266:SF3 7 163 1.4E-61 T 13-09-2016 THL1_RS05550 239854a3c63fd949be010b15efbe2d9a 260 SUPERFAMILY SSF46626 201 223 1.02E-45 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS05550 239854a3c63fd949be010b15efbe2d9a 260 SUPERFAMILY SSF46626 22 161 1.02E-45 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS23110 7d8e4609ed2a9b01f8ef1426d5163d12 393 Pfam PF01370 NAD dependent epimerase/dehydratase family 19 81 1.5E-4 T 13-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 THL1_RS23110 7d8e4609ed2a9b01f8ef1426d5163d12 393 Gene3D G3DSA:3.40.50.20 5 120 1.4E-40 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS23110 7d8e4609ed2a9b01f8ef1426d5163d12 393 SUPERFAMILY SSF52440 4 112 2.01E-34 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS23110 7d8e4609ed2a9b01f8ef1426d5163d12 393 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 14 392 3.2E-194 T 13-09-2016 IPR005862 Phosphoribosylglycinamide formyltransferase 2 GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 UniPathway: UPA00074 THL1_RS23110 7d8e4609ed2a9b01f8ef1426d5163d12 393 SUPERFAMILY SSF56059 120 386 2.02E-57 T 13-09-2016 THL1_RS23110 7d8e4609ed2a9b01f8ef1426d5163d12 393 Gene3D G3DSA:3.30.1490.20 123 198 2.0E-26 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS23110 7d8e4609ed2a9b01f8ef1426d5163d12 393 PANTHER PTHR11609 1 382 1.8E-222 T 13-09-2016 THL1_RS23110 7d8e4609ed2a9b01f8ef1426d5163d12 393 Gene3D G3DSA:3.30.470.20 199 388 1.7E-71 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS23110 7d8e4609ed2a9b01f8ef1426d5163d12 393 Pfam PF02222 ATP-grasp domain 123 295 1.8E-53 T 13-09-2016 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type UniPathway: UPA00074 THL1_RS23110 7d8e4609ed2a9b01f8ef1426d5163d12 393 Hamap MF_01643 Phosphoribosylglycinamide formyltransferase 2 [purT]. 8 392 53.132 T 13-09-2016 IPR005862 Phosphoribosylglycinamide formyltransferase 2 GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 UniPathway: UPA00074 THL1_RS23110 7d8e4609ed2a9b01f8ef1426d5163d12 393 PANTHER PTHR11609:SF7 1 382 1.8E-222 T 13-09-2016 THL1_RS12605 c87e87c1ad0c235082458b5aade466d3 401 Pfam PF00108 Thiolase, N-terminal domain 5 268 1.4E-77 T 13-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THL1_RS12605 c87e87c1ad0c235082458b5aade466d3 401 PANTHER PTHR18919:SF91 1 401 2.2E-245 T 13-09-2016 THL1_RS12605 c87e87c1ad0c235082458b5aade466d3 401 Pfam PF02803 Thiolase, C-terminal domain 277 400 1.8E-43 T 13-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THL1_RS12605 c87e87c1ad0c235082458b5aade466d3 401 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 399 5.3E-140 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS12605 c87e87c1ad0c235082458b5aade466d3 401 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 13-09-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 THL1_RS12605 c87e87c1ad0c235082458b5aade466d3 401 Gene3D G3DSA:3.40.47.10 155 200 1.5E-59 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS12605 c87e87c1ad0c235082458b5aade466d3 401 Gene3D G3DSA:3.40.47.10 283 400 1.5E-59 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS12605 c87e87c1ad0c235082458b5aade466d3 401 TIGRFAM TIGR02430 pcaF: 3-oxoadipyl-CoA thiolase 3 401 9.8E-224 T 13-09-2016 IPR012793 Beta-ketoadipyl CoA thiolase GO:0016747|GO:0019619 KEGG: 00250+2.3.1.17|KEGG: 00360+2.3.1.174|KEGG: 00362+2.3.1.174|MetaCyc: PWY-1361|MetaCyc: PWY-2361|MetaCyc: PWY-6185 THL1_RS12605 c87e87c1ad0c235082458b5aade466d3 401 SUPERFAMILY SSF53901 277 400 3.77E-45 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS12605 c87e87c1ad0c235082458b5aade466d3 401 PIRSF PIRSF000429 1 401 1.4E-133 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS12605 c87e87c1ad0c235082458b5aade466d3 401 PANTHER PTHR18919 1 401 2.2E-245 T 13-09-2016 THL1_RS12605 c87e87c1ad0c235082458b5aade466d3 401 SUPERFAMILY SSF53901 4 276 4.76E-84 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS12605 c87e87c1ad0c235082458b5aade466d3 401 Gene3D G3DSA:3.40.47.10 4 126 1.7E-71 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS12605 c87e87c1ad0c235082458b5aade466d3 401 Gene3D G3DSA:3.40.47.10 201 282 1.7E-71 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS12605 c87e87c1ad0c235082458b5aade466d3 401 ProSitePatterns PS00099 Thiolases active site. 382 395 - T 13-09-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 THL1_RS12605 c87e87c1ad0c235082458b5aade466d3 401 ProSitePatterns PS00737 Thiolases signature 2. 347 363 - T 13-09-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 THL1_RS01105 a38aa6e4eba5ae065141cda8f38d37ea 413 Gene3D G3DSA:3.50.50.60 186 266 1.7E-56 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01105 a38aa6e4eba5ae065141cda8f38d37ea 413 Gene3D G3DSA:3.50.50.60 109 131 1.7E-56 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01105 a38aa6e4eba5ae065141cda8f38d37ea 413 Gene3D G3DSA:3.50.50.60 2 59 1.7E-56 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01105 a38aa6e4eba5ae065141cda8f38d37ea 413 Gene3D G3DSA:3.50.50.60 355 412 1.7E-56 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01105 a38aa6e4eba5ae065141cda8f38d37ea 413 PANTHER PTHR13847 108 413 1.1E-104 T 13-09-2016 THL1_RS01105 a38aa6e4eba5ae065141cda8f38d37ea 413 PANTHER PTHR13847:SF216 108 413 1.1E-104 T 13-09-2016 THL1_RS01105 a38aa6e4eba5ae065141cda8f38d37ea 413 PANTHER PTHR13847 5 61 1.1E-104 T 13-09-2016 THL1_RS01105 a38aa6e4eba5ae065141cda8f38d37ea 413 Pfam PF01266 FAD dependent oxidoreductase 4 394 7.5E-53 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS01105 a38aa6e4eba5ae065141cda8f38d37ea 413 PANTHER PTHR13847:SF216 5 61 1.1E-104 T 13-09-2016 THL1_RS01105 a38aa6e4eba5ae065141cda8f38d37ea 413 SUPERFAMILY SSF54373 270 355 2.0E-5 T 13-09-2016 THL1_RS01105 a38aa6e4eba5ae065141cda8f38d37ea 413 SUPERFAMILY SSF51905 108 267 5.31E-46 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01105 a38aa6e4eba5ae065141cda8f38d37ea 413 SUPERFAMILY SSF51905 355 412 5.31E-46 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01105 a38aa6e4eba5ae065141cda8f38d37ea 413 SUPERFAMILY SSF51905 2 55 5.31E-46 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS26490 1ec77026342a104be8f52def6c29572a 324 SUPERFAMILY SSF53474 1 297 4.65E-62 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS26490 1ec77026342a104be8f52def6c29572a 324 PANTHER PTHR10992:SF860 1 174 3.7E-118 T 13-09-2016 THL1_RS26490 1ec77026342a104be8f52def6c29572a 324 Gene3D G3DSA:3.40.50.1820 14 298 7.8E-70 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS26490 1ec77026342a104be8f52def6c29572a 324 Pfam PF00561 alpha/beta hydrolase fold 36 295 9.7E-35 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS26490 1ec77026342a104be8f52def6c29572a 324 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 6.0E-5 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS26490 1ec77026342a104be8f52def6c29572a 324 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 6.0E-5 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS26490 1ec77026342a104be8f52def6c29572a 324 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 6.0E-5 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS26490 1ec77026342a104be8f52def6c29572a 324 PANTHER PTHR10992:SF860 210 311 3.7E-118 T 13-09-2016 THL1_RS26490 1ec77026342a104be8f52def6c29572a 324 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 37 45 1.8E-13 T 13-09-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 THL1_RS26490 1ec77026342a104be8f52def6c29572a 324 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 63 74 1.8E-13 T 13-09-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 THL1_RS26490 1ec77026342a104be8f52def6c29572a 324 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 106 120 1.8E-13 T 13-09-2016 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 THL1_RS26490 1ec77026342a104be8f52def6c29572a 324 PANTHER PTHR10992 210 311 3.7E-118 T 13-09-2016 THL1_RS26490 1ec77026342a104be8f52def6c29572a 324 PANTHER PTHR10992 1 174 3.7E-118 T 13-09-2016 THL1_RS26490 1ec77026342a104be8f52def6c29572a 324 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 9 311 7.8E-129 T 13-09-2016 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 THL1_RS26490 1ec77026342a104be8f52def6c29572a 324 PIRSF PIRSF006431 1 315 1.0E-135 T 13-09-2016 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 THL1_RS04095 435d591bc49feea72e82dcda93c68f17 455 PANTHER PTHR11785:SF337 6 445 2.7E-143 T 13-09-2016 THL1_RS04095 435d591bc49feea72e82dcda93c68f17 455 PANTHER PTHR11785 6 445 2.7E-143 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS04095 435d591bc49feea72e82dcda93c68f17 455 Pfam PF13520 Amino acid permease 10 418 5.9E-43 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS04095 435d591bc49feea72e82dcda93c68f17 455 PIRSF PIRSF006060 1 452 2.5E-66 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS04095 435d591bc49feea72e82dcda93c68f17 455 TIGRFAM TIGR00908 2A0305: ethanolamine permease 4 450 2.1E-190 T 13-09-2016 IPR004757 Ethanolamine permease THL1_RS10400 aec91655c0575777d1d6f592a43705ab 390 Gene3D G3DSA:3.20.20.450 4 227 1.8E-47 T 13-09-2016 IPR001633 EAL domain THL1_RS10400 aec91655c0575777d1d6f592a43705ab 390 Pfam PF10388 EAL-domain associated signalling protein domain 239 383 6.6E-16 T 13-09-2016 IPR018842 YkuI, C-terminal THL1_RS10400 aec91655c0575777d1d6f592a43705ab 390 Gene3D G3DSA:3.30.450.20 289 387 1.1E-36 T 13-09-2016 THL1_RS10400 aec91655c0575777d1d6f592a43705ab 390 PANTHER PTHR33121 10 272 1.1E-38 T 13-09-2016 THL1_RS10400 aec91655c0575777d1d6f592a43705ab 390 SMART SM00052 3 232 2.0E-29 T 13-09-2016 IPR001633 EAL domain THL1_RS10400 aec91655c0575777d1d6f592a43705ab 390 SUPERFAMILY SSF103190 254 385 2.2E-33 T 13-09-2016 IPR029151 Periplasmic sensor domain-like THL1_RS10400 aec91655c0575777d1d6f592a43705ab 390 Pfam PF00563 EAL domain 9 227 5.5E-43 T 13-09-2016 IPR001633 EAL domain THL1_RS10400 aec91655c0575777d1d6f592a43705ab 390 SUPERFAMILY SSF141868 4 228 7.59E-52 T 13-09-2016 IPR001633 EAL domain THL1_RS21845 22dc53d746079f05504ef13eeb36db3b 465 Gene3D G3DSA:3.40.50.450 128 455 8.6E-118 T 13-09-2016 THL1_RS21845 22dc53d746079f05504ef13eeb36db3b 465 PANTHER PTHR31223:SF12 89 344 2.4E-165 T 13-09-2016 THL1_RS21845 22dc53d746079f05504ef13eeb36db3b 465 PANTHER PTHR31223:SF12 361 386 2.4E-165 T 13-09-2016 THL1_RS21845 22dc53d746079f05504ef13eeb36db3b 465 Pfam PF11892 Domain of unknown function (DUF3412) 336 456 3.5E-56 T 13-09-2016 IPR021826 Protein of unknown function DUF3412 THL1_RS21845 22dc53d746079f05504ef13eeb36db3b 465 Pfam PF14793 Domain of unknown function (DUF4478) 10 116 2.1E-43 T 13-09-2016 IPR027820 Domain of unknown function DUF4478 THL1_RS21845 22dc53d746079f05504ef13eeb36db3b 465 Pfam PF03641 Possible lysine decarboxylase 194 330 5.0E-30 T 13-09-2016 IPR031100 LOG family THL1_RS21845 22dc53d746079f05504ef13eeb36db3b 465 SUPERFAMILY SSF102405 122 328 9.77E-40 T 13-09-2016 THL1_RS21845 22dc53d746079f05504ef13eeb36db3b 465 PANTHER PTHR31223 89 344 2.4E-165 T 13-09-2016 THL1_RS21845 22dc53d746079f05504ef13eeb36db3b 465 PANTHER PTHR31223 361 386 2.4E-165 T 13-09-2016 THL1_RS21845 22dc53d746079f05504ef13eeb36db3b 465 Gene3D G3DSA:3.30.1850.10 7 119 8.4E-49 T 13-09-2016 IPR027820 Domain of unknown function DUF4478 THL1_RS28410 e257ec37de1519dff49e5a7e91dff3bb 454 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 449 43.833 T 13-09-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00113|UniPathway: UPA00113|UniPathway: UPA00973 THL1_RS28410 e257ec37de1519dff49e5a7e91dff3bb 454 SUPERFAMILY SSF53448 1 249 5.05E-65 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS28410 e257ec37de1519dff49e5a7e91dff3bb 454 Gene3D G3DSA:2.160.10.10 322 450 1.9E-36 T 13-09-2016 THL1_RS28410 e257ec37de1519dff49e5a7e91dff3bb 454 Gene3D G3DSA:3.90.550.10 1 242 1.2E-71 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS28410 e257ec37de1519dff49e5a7e91dff3bb 454 SUPERFAMILY SSF51161 252 438 9.61E-52 T 13-09-2016 IPR011004 Trimeric LpxA-like THL1_RS28410 e257ec37de1519dff49e5a7e91dff3bb 454 PANTHER PTHR22572 4 446 7.6E-226 T 13-09-2016 THL1_RS28410 e257ec37de1519dff49e5a7e91dff3bb 454 Gene3D G3DSA:2.160.10.10 243 321 6.9E-16 T 13-09-2016 THL1_RS28410 e257ec37de1519dff49e5a7e91dff3bb 454 PANTHER PTHR22572:SF115 4 446 7.6E-226 T 13-09-2016 THL1_RS28410 e257ec37de1519dff49e5a7e91dff3bb 454 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 263 296 4.9E-6 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS28410 e257ec37de1519dff49e5a7e91dff3bb 454 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 392 425 2.7E-7 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS28410 e257ec37de1519dff49e5a7e91dff3bb 454 Pfam PF12804 MobA-like NTP transferase domain 6 131 4.6E-23 T 13-09-2016 IPR025877 MobA-like NTP transferase THL1_RS28410 e257ec37de1519dff49e5a7e91dff3bb 454 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 4 450 9.9E-200 T 13-09-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00113|UniPathway: UPA00113|UniPathway: UPA00973 THL1_RS02605 68da166b471df2c762caa4aaa8cc52f4 268 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 7 260 1.2E-83 T 13-09-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 THL1_RS02605 68da166b471df2c762caa4aaa8cc52f4 268 Pfam PF00398 Ribosomal RNA adenine dimethylase 7 259 1.1E-62 T 13-09-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm THL1_RS02605 68da166b471df2c762caa4aaa8cc52f4 268 Gene3D G3DSA:1.10.8.100 198 262 5.1E-25 T 13-09-2016 IPR023165 rRNA adenine dimethylase-like THL1_RS02605 68da166b471df2c762caa4aaa8cc52f4 268 SUPERFAMILY SSF53335 6 263 1.24E-78 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS02605 68da166b471df2c762caa4aaa8cc52f4 268 Gene3D G3DSA:3.40.50.150 3 195 1.4E-70 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS02605 68da166b471df2c762caa4aaa8cc52f4 268 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 39 66 - T 13-09-2016 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 THL1_RS02605 68da166b471df2c762caa4aaa8cc52f4 268 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 7 262 57.77 T 13-09-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 THL1_RS02605 68da166b471df2c762caa4aaa8cc52f4 268 PANTHER PTHR11727 1 264 1.6E-98 T 13-09-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm THL1_RS02605 68da166b471df2c762caa4aaa8cc52f4 268 SMART SM00650 23 195 4.3E-89 T 13-09-2016 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 THL1_RS24050 93901c7105290377d7547d316637388e 69 Gene3D G3DSA:3.40.1620.10 1 50 1.5E-10 T 13-09-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THL1_RS24050 93901c7105290377d7547d316637388e 69 PANTHER PTHR33713:SF6 1 69 7.6E-20 T 13-09-2016 THL1_RS24050 93901c7105290377d7547d316637388e 69 SUPERFAMILY SSF143120 1 68 2.88E-20 T 13-09-2016 THL1_RS24050 93901c7105290377d7547d316637388e 69 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 55 6.2E-12 T 13-09-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THL1_RS24050 93901c7105290377d7547d316637388e 69 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 68 1.6E-20 T 13-09-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THL1_RS24050 93901c7105290377d7547d316637388e 69 PANTHER PTHR33713 1 69 7.6E-20 T 13-09-2016 THL1_RS26300 8b3732b5f2b67a619077594fe73502b8 700 Pfam PF03958 Bacterial type II/III secretion system short domain 381 449 3.5E-14 T 13-09-2016 IPR005644 NolW-like THL1_RS26300 8b3732b5f2b67a619077594fe73502b8 700 Pfam PF07660 Secretin and TonB N terminus short domain 307 353 3.7E-9 T 13-09-2016 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 THL1_RS26300 8b3732b5f2b67a619077594fe73502b8 700 PRINTS PR00811 Bacterial general secretion pathway protein D signature 449 459 3.7E-18 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS26300 8b3732b5f2b67a619077594fe73502b8 700 PRINTS PR00811 Bacterial general secretion pathway protein D signature 566 576 3.7E-18 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS26300 8b3732b5f2b67a619077594fe73502b8 700 PRINTS PR00811 Bacterial general secretion pathway protein D signature 656 674 3.7E-18 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS26300 8b3732b5f2b67a619077594fe73502b8 700 PRINTS PR00811 Bacterial general secretion pathway protein D signature 679 693 3.7E-18 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS26300 8b3732b5f2b67a619077594fe73502b8 700 PRINTS PR00811 Bacterial general secretion pathway protein D signature 531 555 3.7E-18 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS26300 8b3732b5f2b67a619077594fe73502b8 700 SMART SM00965 306 354 1.0E-10 T 13-09-2016 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 THL1_RS26300 8b3732b5f2b67a619077594fe73502b8 700 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 281 692 1.2E-161 T 13-09-2016 IPR013355 Type IV pilus secretin PilQ GO:0009297|GO:0009306 THL1_RS26300 8b3732b5f2b67a619077594fe73502b8 700 PANTHER PTHR30604 7 700 4.9E-128 T 13-09-2016 THL1_RS26300 8b3732b5f2b67a619077594fe73502b8 700 Pfam PF00263 Bacterial type II and III secretion system protein 535 691 7.0E-49 T 13-09-2016 IPR004846 Type II/III secretion system GO:0009306 THL1_RS26300 8b3732b5f2b67a619077594fe73502b8 700 Pfam PF11741 AMIN domain 40 119 3.9E-6 T 13-09-2016 IPR021731 AMIN domain THL1_RS26215 107c488b2f6ff67f3d337ee4565e5b56 279 PANTHER PTHR37426:SF1 1 279 2.2E-136 T 13-09-2016 THL1_RS26215 107c488b2f6ff67f3d337ee4565e5b56 279 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 1 266 39.075 T 13-09-2016 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 THL1_RS26215 107c488b2f6ff67f3d337ee4565e5b56 279 Gene3D G3DSA:3.40.50.150 1 279 4.8E-103 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS26215 107c488b2f6ff67f3d337ee4565e5b56 279 PANTHER PTHR37426 1 279 2.2E-136 T 13-09-2016 THL1_RS26215 107c488b2f6ff67f3d337ee4565e5b56 279 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 32 276 3.4E-98 T 13-09-2016 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 THL1_RS26215 107c488b2f6ff67f3d337ee4565e5b56 279 SUPERFAMILY SSF53335 8 275 1.11E-86 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS23670 6d2626766719b4fcf4a411f7ff10003f 677 PANTHER PTHR23406:SF3 146 672 2.2E-18 T 13-09-2016 THL1_RS23670 6d2626766719b4fcf4a411f7ff10003f 677 SUPERFAMILY SSF53659 372 671 1.01E-65 T 13-09-2016 THL1_RS23670 6d2626766719b4fcf4a411f7ff10003f 677 SUPERFAMILY SSF52540 1 220 7.33E-31 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS23670 6d2626766719b4fcf4a411f7ff10003f 677 PANTHER PTHR23406 146 672 2.2E-18 T 13-09-2016 THL1_RS23670 6d2626766719b4fcf4a411f7ff10003f 677 Pfam PF07085 DRTGG domain 213 325 1.1E-29 T 13-09-2016 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 THL1_RS23670 6d2626766719b4fcf4a411f7ff10003f 677 SUPERFAMILY SSF75138 209 333 7.85E-25 T 13-09-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like THL1_RS23670 6d2626766719b4fcf4a411f7ff10003f 677 Gene3D G3DSA:3.40.1390.20 208 345 1.1E-29 T 13-09-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like THL1_RS23670 6d2626766719b4fcf4a411f7ff10003f 677 PIRSF PIRSF006107 1 676 5.3E-286 T 13-09-2016 IPR016475 Phosphate acetyltransferase, bacteria GO:0008959 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 THL1_RS23670 6d2626766719b4fcf4a411f7ff10003f 677 Pfam PF01515 Phosphate acetyl/butaryl transferase 371 668 1.2E-77 T 13-09-2016 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 THL1_RS23670 6d2626766719b4fcf4a411f7ff10003f 677 Gene3D G3DSA:3.40.50.10750 503 644 1.0E-32 T 13-09-2016 THL1_RS23670 6d2626766719b4fcf4a411f7ff10003f 677 Gene3D G3DSA:3.40.50.300 1 207 4.8E-16 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS23670 6d2626766719b4fcf4a411f7ff10003f 677 Pfam PF13500 AAA domain 3 210 3.8E-33 T 13-09-2016 THL1_RS21865 0a83bf981b773309ed464322ce30ca2a 343 Gene3D G3DSA:1.10.10.60 280 330 1.1E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21865 0a83bf981b773309ed464322ce30ca2a 343 SUPERFAMILY SSF46689 226 275 1.21E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21865 0a83bf981b773309ed464322ce30ca2a 343 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 279 321 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS21865 0a83bf981b773309ed464322ce30ca2a 343 Gene3D G3DSA:3.40.50.880 18 230 1.1E-25 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS21865 0a83bf981b773309ed464322ce30ca2a 343 Pfam PF12833 Helix-turn-helix domain 248 325 1.3E-26 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS21865 0a83bf981b773309ed464322ce30ca2a 343 PANTHER PTHR11019 66 333 2.0E-55 T 13-09-2016 THL1_RS21865 0a83bf981b773309ed464322ce30ca2a 343 SUPERFAMILY SSF52317 18 204 1.05E-31 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS21865 0a83bf981b773309ed464322ce30ca2a 343 PANTHER PTHR11019:SF90 21 40 2.0E-55 T 13-09-2016 THL1_RS21865 0a83bf981b773309ed464322ce30ca2a 343 PANTHER PTHR11019:SF90 66 333 2.0E-55 T 13-09-2016 THL1_RS21865 0a83bf981b773309ed464322ce30ca2a 343 Gene3D G3DSA:1.10.10.60 231 279 7.3E-18 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21865 0a83bf981b773309ed464322ce30ca2a 343 SMART SM00342 242 325 5.1E-33 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS21865 0a83bf981b773309ed464322ce30ca2a 343 PANTHER PTHR11019 21 40 2.0E-55 T 13-09-2016 THL1_RS21865 0a83bf981b773309ed464322ce30ca2a 343 SUPERFAMILY SSF46689 278 330 1.12E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS18305 5217d767e3a7ee02b809b33b519ea1d8 388 PANTHER PTHR11751:SF294 10 382 2.6E-119 T 13-09-2016 THL1_RS18305 5217d767e3a7ee02b809b33b519ea1d8 388 Pfam PF00155 Aminotransferase class I and II 52 375 1.1E-33 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS18305 5217d767e3a7ee02b809b33b519ea1d8 388 Gene3D G3DSA:3.40.640.10 49 259 1.2E-65 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS18305 5217d767e3a7ee02b809b33b519ea1d8 388 SUPERFAMILY SSF53383 2 381 9.32E-94 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS18305 5217d767e3a7ee02b809b33b519ea1d8 388 PANTHER PTHR11751 10 382 2.6E-119 T 13-09-2016 THL1_RS18305 5217d767e3a7ee02b809b33b519ea1d8 388 Gene3D G3DSA:3.90.1150.10 260 381 6.5E-9 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS08885 e2abe08c78f1acae8dba868d92455aa1 450 PANTHER PTHR33678 1 441 2.1E-91 T 13-09-2016 THL1_RS08885 e2abe08c78f1acae8dba868d92455aa1 450 Pfam PF13007 Transposase C of IS166 homeodomain 8 46 2.3E-6 T 13-09-2016 IPR024463 Transposase TnpC, homeodomain THL1_RS08885 e2abe08c78f1acae8dba868d92455aa1 450 Pfam PF13005 zinc-finger binding domain of transposase IS66 56 97 2.5E-13 T 13-09-2016 IPR024474 Zinc-finger binding domain of transposase IS66 THL1_RS08885 e2abe08c78f1acae8dba868d92455aa1 450 Pfam PF13817 IS66 C-terminal element 404 442 7.5E-19 T 13-09-2016 THL1_RS08885 e2abe08c78f1acae8dba868d92455aa1 450 Pfam PF03050 Transposase IS66 family 112 397 5.9E-102 T 13-09-2016 IPR004291 Transposase, IS66 THL1_RS08885 e2abe08c78f1acae8dba868d92455aa1 450 PANTHER PTHR33678:SF1 1 441 2.1E-91 T 13-09-2016 THL1_RS10590 88353f9580d3c6151413779545282574 146 PIRSF PIRSF006276 1 144 9.9E-51 T 13-09-2016 IPR006015 Universal stress protein A THL1_RS10590 88353f9580d3c6151413779545282574 146 SUPERFAMILY SSF52402 3 141 9.21E-38 T 13-09-2016 THL1_RS10590 88353f9580d3c6151413779545282574 146 PANTHER PTHR31964:SF42 1 141 4.0E-32 T 13-09-2016 THL1_RS10590 88353f9580d3c6151413779545282574 146 PANTHER PTHR31964 1 141 4.0E-32 T 13-09-2016 THL1_RS10590 88353f9580d3c6151413779545282574 146 Pfam PF00582 Universal stress protein family 3 141 7.1E-35 T 13-09-2016 IPR006016 UspA GO:0006950 THL1_RS10590 88353f9580d3c6151413779545282574 146 Gene3D G3DSA:3.40.50.620 3 143 7.2E-41 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS10590 88353f9580d3c6151413779545282574 146 PRINTS PR01438 Universal stress protein signature 3 21 9.2E-15 T 13-09-2016 IPR006015 Universal stress protein A THL1_RS10590 88353f9580d3c6151413779545282574 146 PRINTS PR01438 Universal stress protein signature 119 141 9.2E-15 T 13-09-2016 IPR006015 Universal stress protein A THL1_RS10590 88353f9580d3c6151413779545282574 146 PRINTS PR01438 Universal stress protein signature 102 114 9.2E-15 T 13-09-2016 IPR006015 Universal stress protein A THL1_RS20910 d254596acbb7aef1c0207804009ea25c 504 PANTHER PTHR23309 387 496 2.7E-178 T 13-09-2016 THL1_RS20910 d254596acbb7aef1c0207804009ea25c 504 SUPERFAMILY SSF48179 410 493 4.25E-18 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS20910 d254596acbb7aef1c0207804009ea25c 504 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 410 492 8.3E-18 T 13-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS20910 d254596acbb7aef1c0207804009ea25c 504 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 284 9.7E-25 T 13-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS20910 d254596acbb7aef1c0207804009ea25c 504 PANTHER PTHR23309:SF12 1 303 2.7E-178 T 13-09-2016 THL1_RS20910 d254596acbb7aef1c0207804009ea25c 504 Gene3D G3DSA:1.10.1040.10 410 492 4.2E-20 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS20910 d254596acbb7aef1c0207804009ea25c 504 Gene3D G3DSA:1.10.1040.10 189 284 8.7E-26 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS20910 d254596acbb7aef1c0207804009ea25c 504 SUPERFAMILY SSF51735 2 186 8.22E-49 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20910 d254596acbb7aef1c0207804009ea25c 504 PANTHER PTHR23309 1 303 2.7E-178 T 13-09-2016 THL1_RS20910 d254596acbb7aef1c0207804009ea25c 504 SUPERFAMILY SSF48179 186 297 2.55E-28 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS20910 d254596acbb7aef1c0207804009ea25c 504 Gene3D G3DSA:3.40.50.720 4 188 5.8E-52 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20910 d254596acbb7aef1c0207804009ea25c 504 PANTHER PTHR23309:SF12 387 496 2.7E-178 T 13-09-2016 THL1_RS20910 d254596acbb7aef1c0207804009ea25c 504 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 184 6.2E-55 T 13-09-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 265 411 1.6E-12 T 13-09-2016 IPR000160 GGDEF domain THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 Gene3D G3DSA:3.30.70.270 270 413 7.6E-25 T 13-09-2016 THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 Pfam PF00989 PAS fold 147 250 7.0E-8 T 13-09-2016 IPR013767 PAS fold GO:0006355 THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 Pfam PF00563 EAL domain 444 675 1.5E-56 T 13-09-2016 IPR001633 EAL domain THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 SMART SM00267 256 426 1.7E-17 T 13-09-2016 IPR000160 GGDEF domain THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 SUPERFAMILY SSF141868 444 679 3.27E-53 T 13-09-2016 IPR001633 EAL domain THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 Gene3D G3DSA:3.30.450.20 131 250 1.1E-16 T 13-09-2016 THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 SMART SM00091 144 210 0.0023 T 13-09-2016 IPR000014 PAS domain THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 SUPERFAMILY SSF55785 132 250 4.54E-17 T 13-09-2016 IPR000014 PAS domain THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 Pfam PF00990 Diguanylate cyclase, GGDEF domain 269 414 6.9E-19 T 13-09-2016 IPR000160 GGDEF domain THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 Gene3D G3DSA:3.40.50.2300 6 120 1.6E-6 T 13-09-2016 THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 SMART SM00052 437 681 8.8E-39 T 13-09-2016 IPR001633 EAL domain THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 Gene3D G3DSA:3.20.20.450 443 679 3.5E-53 T 13-09-2016 IPR001633 EAL domain THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 SUPERFAMILY SSF52172 6 134 4.05E-9 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 SUPERFAMILY SSF55073 273 412 3.37E-21 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 PANTHER PTHR33121:SF10 437 676 3.5E-40 T 13-09-2016 THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 140 263 8.3E-11 T 13-09-2016 IPR000014 PAS domain THL1_RS25935 6a56f52f3bca3cc466abeba1d244f2d6 689 PANTHER PTHR33121 437 676 3.5E-40 T 13-09-2016 THL1_RS07705 23eab8ddbb9938f22af62f76ec2a8c15 303 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 278 7.6E-42 T 13-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 THL1_RS07705 23eab8ddbb9938f22af62f76ec2a8c15 303 PANTHER PTHR11795 1 301 3.1E-102 T 13-09-2016 THL1_RS07705 23eab8ddbb9938f22af62f76ec2a8c15 303 PANTHER PTHR11795:SF404 1 301 3.1E-102 T 13-09-2016 THL1_RS00985 2c9dac0c24016eedca4276712052a019 356 PANTHER PTHR30222:SF11 1 356 8.7E-198 T 13-09-2016 THL1_RS00985 2c9dac0c24016eedca4276712052a019 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 255 274 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00985 2c9dac0c24016eedca4276712052a019 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 300 326 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00985 2c9dac0c24016eedca4276712052a019 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 82 95 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00985 2c9dac0c24016eedca4276712052a019 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 39 60 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00985 2c9dac0c24016eedca4276712052a019 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 115 131 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00985 2c9dac0c24016eedca4276712052a019 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 168 187 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00985 2c9dac0c24016eedca4276712052a019 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 23 39 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00985 2c9dac0c24016eedca4276712052a019 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 66 80 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00985 2c9dac0c24016eedca4276712052a019 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 145 159 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00985 2c9dac0c24016eedca4276712052a019 356 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 205 224 6.2E-67 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00985 2c9dac0c24016eedca4276712052a019 356 Gene3D G3DSA:3.40.190.10 139 304 2.9E-75 T 13-09-2016 THL1_RS00985 2c9dac0c24016eedca4276712052a019 356 PANTHER PTHR30222 1 356 8.7E-198 T 13-09-2016 THL1_RS00985 2c9dac0c24016eedca4276712052a019 356 PIRSF PIRSF019574 1 356 1.8E-142 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00985 2c9dac0c24016eedca4276712052a019 356 Pfam PF13416 Bacterial extracellular solute-binding protein 35 315 2.4E-32 T 13-09-2016 THL1_RS00985 2c9dac0c24016eedca4276712052a019 356 Gene3D G3DSA:3.40.190.10 19 138 1.8E-25 T 13-09-2016 THL1_RS00985 2c9dac0c24016eedca4276712052a019 356 SUPERFAMILY SSF53850 17 355 1.27E-100 T 13-09-2016 THL1_RS02420 307262942f30ee0acf7ae496b5b30977 341 Pfam PF13609 Gram-negative porin 6 308 1.2E-23 T 13-09-2016 THL1_RS02420 307262942f30ee0acf7ae496b5b30977 341 Gene3D G3DSA:2.40.160.10 18 341 6.7E-45 T 13-09-2016 IPR023614 Porin domain THL1_RS02420 307262942f30ee0acf7ae496b5b30977 341 SUPERFAMILY SSF56935 18 341 1.37E-39 T 13-09-2016 THL1_RS05690 c3418fc02a881481f5c9763fe149b8c7 405 PANTHER PTHR23100 16 405 6.1E-171 T 13-09-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 THL1_RS05690 c3418fc02a881481f5c9763fe149b8c7 405 SUPERFAMILY SSF56266 14 402 1.23E-132 T 13-09-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 THL1_RS05690 c3418fc02a881481f5c9763fe149b8c7 405 PANTHER PTHR23100:SF0 16 405 6.1E-171 T 13-09-2016 THL1_RS05690 c3418fc02a881481f5c9763fe149b8c7 405 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 14 405 1.5E-117 T 13-09-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 THL1_RS05690 c3418fc02a881481f5c9763fe149b8c7 405 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 405 153.091 T 13-09-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 THL1_RS05690 c3418fc02a881481f5c9763fe149b8c7 405 Pfam PF01960 ArgJ family 21 405 3.7E-136 T 13-09-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 THL1_RS05690 c3418fc02a881481f5c9763fe149b8c7 405 Gene3D G3DSA:3.60.70.12 11 276 1.7E-91 T 13-09-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 THL1_RS05690 c3418fc02a881481f5c9763fe149b8c7 405 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 22 405 0.0 T 13-09-2016 THL1_RS22370 0b10bc7e7c0fa4f79a964e841b9eb7c1 634 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 15 634 33.954 T 13-09-2016 IPR023051 Potassium uptake protein, low affinity, Kup THL1_RS22370 0b10bc7e7c0fa4f79a964e841b9eb7c1 634 PANTHER PTHR30540:SF7 28 560 4.8E-239 T 13-09-2016 THL1_RS22370 0b10bc7e7c0fa4f79a964e841b9eb7c1 634 Pfam PF02705 K+ potassium transporter 25 556 2.0E-208 T 13-09-2016 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 THL1_RS22370 0b10bc7e7c0fa4f79a964e841b9eb7c1 634 PANTHER PTHR30540 28 560 4.8E-239 T 13-09-2016 THL1_RS27915 d6d5adb58b008d528c13193722929cf6 285 SUPERFAMILY SSF51735 11 280 6.41E-38 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS27915 d6d5adb58b008d528c13193722929cf6 285 PANTHER PTHR10366 6 281 3.5E-44 T 13-09-2016 THL1_RS27915 d6d5adb58b008d528c13193722929cf6 285 Gene3D G3DSA:3.90.25.10 201 278 4.8E-4 T 13-09-2016 THL1_RS27915 d6d5adb58b008d528c13193722929cf6 285 PANTHER PTHR10366:SF430 6 281 3.5E-44 T 13-09-2016 THL1_RS27915 d6d5adb58b008d528c13193722929cf6 285 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 166 4.1E-10 T 13-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 THL1_RS27915 d6d5adb58b008d528c13193722929cf6 285 Gene3D G3DSA:3.40.50.720 7 200 1.1E-23 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS00390 2168b728e8e32d1c76afcf237f5feabb 292 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 37 262 1.4E-17 T 13-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase THL1_RS00390 2168b728e8e32d1c76afcf237f5feabb 292 Gene3D G3DSA:3.60.10.10 32 194 6.5E-5 T 13-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase THL1_RS00390 2168b728e8e32d1c76afcf237f5feabb 292 SUPERFAMILY SSF56219 27 273 5.63E-33 T 13-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase THL1_RS00390 2168b728e8e32d1c76afcf237f5feabb 292 PANTHER PTHR14859 69 282 1.3E-35 T 13-09-2016 IPR027317 PGAP2-interacting protein THL1_RS00390 2168b728e8e32d1c76afcf237f5feabb 292 PANTHER PTHR14859 16 50 1.3E-35 T 13-09-2016 IPR027317 PGAP2-interacting protein THL1_RS00390 2168b728e8e32d1c76afcf237f5feabb 292 Gene3D G3DSA:3.60.10.10 195 271 6.4E-4 T 13-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase THL1_RS15395 8ce4d43e425d9c2d803ce298a8861bde 203 SUPERFAMILY SSF52833 47 176 1.81E-19 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS15395 8ce4d43e425d9c2d803ce298a8861bde 203 Pfam PF00578 AhpC/TSA family 50 159 1.8E-7 T 13-09-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS15395 8ce4d43e425d9c2d803ce298a8861bde 203 Gene3D G3DSA:3.40.30.10 14 174 3.5E-15 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS15395 8ce4d43e425d9c2d803ce298a8861bde 203 TIGRFAM TIGR02661 MauD: methylamine dehydrogenase accessory protein MauD 4 191 1.0E-62 T 13-09-2016 IPR013478 Methylamine dehydrogenase accessory protein MauD GO:0030416 UniPathway: UPA00895 THL1_RS03275 6ddebe90996efb711d37d847b7131a91 268 Gene3D G3DSA:3.40.50.300 5 252 3.2E-79 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03275 6ddebe90996efb711d37d847b7131a91 268 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS03275 6ddebe90996efb711d37d847b7131a91 268 PANTHER PTHR24220 8 252 5.9E-118 T 13-09-2016 THL1_RS03275 6ddebe90996efb711d37d847b7131a91 268 Pfam PF00005 ABC transporter 23 181 1.6E-32 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS03275 6ddebe90996efb711d37d847b7131a91 268 SMART SM00382 31 229 7.9E-16 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS03275 6ddebe90996efb711d37d847b7131a91 268 PIRSF PIRSF039085 3 256 3.2E-102 T 13-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 THL1_RS03275 6ddebe90996efb711d37d847b7131a91 268 PANTHER PTHR24220:SF550 8 252 5.9E-118 T 13-09-2016 THL1_RS03275 6ddebe90996efb711d37d847b7131a91 268 SUPERFAMILY SSF52540 6 251 3.75E-73 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15970 3c6b279314e6d6f7da368cc0af66cfa2 168 PANTHER PTHR36922 1 166 1.2E-82 T 13-09-2016 THL1_RS15970 3c6b279314e6d6f7da368cc0af66cfa2 168 Pfam PF09351 Domain of unknown function (DUF1993) 5 165 8.2E-66 T 13-09-2016 IPR018531 Domain of unknown function DUF1993 THL1_RS15970 3c6b279314e6d6f7da368cc0af66cfa2 168 SUPERFAMILY SSF109854 4 167 3.3E-65 T 13-09-2016 THL1_RS15970 3c6b279314e6d6f7da368cc0af66cfa2 168 Gene3D G3DSA:1.20.120.450 1 166 6.5E-75 T 13-09-2016 IPR027369 DinB/YfiT-like putative metal-dependent hydrolase THL1_RS15970 3c6b279314e6d6f7da368cc0af66cfa2 168 PANTHER PTHR36922:SF1 1 166 1.2E-82 T 13-09-2016 THL1_RS02360 fabf09dbced5319094483d89ab34899f 245 Pfam PF01177 Asp/Glu/Hydantoin racemase 43 207 3.2E-11 T 13-09-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS02360 fabf09dbced5319094483d89ab34899f 245 PANTHER PTHR28047:SF1 1 233 5.1E-54 T 13-09-2016 THL1_RS02360 fabf09dbced5319094483d89ab34899f 245 PANTHER PTHR28047 1 233 5.1E-54 T 13-09-2016 THL1_RS25890 e174bb98c204e30b08b5763201d70395 360 PANTHER PTHR30002:SF4 3 357 8.7E-183 T 13-09-2016 THL1_RS25890 e174bb98c204e30b08b5763201d70395 360 Gene3D G3DSA:3.30.70.20 193 258 1.6E-6 T 13-09-2016 THL1_RS25890 e174bb98c204e30b08b5763201d70395 360 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 8 317 50.358 T 13-09-2016 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS25890 e174bb98c204e30b08b5763201d70395 360 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 195 206 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS25890 e174bb98c204e30b08b5763201d70395 360 Pfam PF13484 4Fe-4S double cluster binding domain 194 258 7.8E-20 T 13-09-2016 THL1_RS25890 e174bb98c204e30b08b5763201d70395 360 Pfam PF08331 Domain of unknown function (DUF1730) 63 141 2.6E-23 T 13-09-2016 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS25890 e174bb98c204e30b08b5763201d70395 360 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 15 351 1.1E-153 T 13-09-2016 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700|UniPathway: UPA00392 THL1_RS25890 e174bb98c204e30b08b5763201d70395 360 PANTHER PTHR30002 3 357 8.7E-183 T 13-09-2016 THL1_RS25890 e174bb98c204e30b08b5763201d70395 360 SUPERFAMILY SSF46548 140 258 8.37E-18 T 13-09-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 THL1_RS11475 dea673866aea79ddbee0475671b9b14c 654 PANTHER PTHR32089 218 654 5.0E-132 T 13-09-2016 THL1_RS11475 dea673866aea79ddbee0475671b9b14c 654 PANTHER PTHR32089:SF64 218 654 5.0E-132 T 13-09-2016 THL1_RS11475 dea673866aea79ddbee0475671b9b14c 654 Pfam PF00672 HAMP domain 305 372 3.0E-14 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS11475 dea673866aea79ddbee0475671b9b14c 654 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 452 651 2.4E-51 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS11475 dea673866aea79ddbee0475671b9b14c 654 SMART SM00283 391 652 2.3E-87 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS11475 dea673866aea79ddbee0475671b9b14c 654 SMART SM01358 37 302 4.9E-29 T 13-09-2016 IPR032255 Helical bimodular sensor domain THL1_RS11475 dea673866aea79ddbee0475671b9b14c 654 Pfam PF16591 Helical bimodular sensor domain 37 300 2.2E-17 T 13-09-2016 IPR032255 Helical bimodular sensor domain THL1_RS11475 dea673866aea79ddbee0475671b9b14c 654 SMART SM00304 324 376 3.9E-10 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS11475 dea673866aea79ddbee0475671b9b14c 654 SMART SM00304 383 429 38.0 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS11475 dea673866aea79ddbee0475671b9b14c 654 SUPERFAMILY SSF58104 344 653 6.54E-80 T 13-09-2016 THL1_RS11475 dea673866aea79ddbee0475671b9b14c 654 Gene3D G3DSA:1.10.287.950 405 622 3.5E-60 T 13-09-2016 THL1_RS11475 dea673866aea79ddbee0475671b9b14c 654 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 163 178 8.3E-20 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS11475 dea673866aea79ddbee0475671b9b14c 654 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 518 547 8.3E-20 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS11475 dea673866aea79ddbee0475671b9b14c 654 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 489 516 8.3E-20 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS26440 c53d2f6a8195c61fc6a72bf3762c48c8 111 PANTHER PTHR21256 3 109 5.2E-44 T 13-09-2016 THL1_RS26440 c53d2f6a8195c61fc6a72bf3762c48c8 111 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 2 92 21.325 T 13-09-2016 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31|UniPathway: UPA00031 THL1_RS26440 c53d2f6a8195c61fc6a72bf3762c48c8 111 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 6 95 1.5E-17 T 13-09-2016 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31|UniPathway: UPA00031 THL1_RS26440 c53d2f6a8195c61fc6a72bf3762c48c8 111 SUPERFAMILY SSF101386 3 96 6.98E-25 T 13-09-2016 THL1_RS26440 c53d2f6a8195c61fc6a72bf3762c48c8 111 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 92 1.6E-29 T 13-09-2016 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31|UniPathway: UPA00031 THL1_RS20235 880616b51de978b43b93e71c1709cecc 319 PANTHER PTHR11614 1 302 7.0E-55 T 13-09-2016 THL1_RS20235 880616b51de978b43b93e71c1709cecc 319 PANTHER PTHR11614:SF87 1 302 7.0E-55 T 13-09-2016 THL1_RS20235 880616b51de978b43b93e71c1709cecc 319 SUPERFAMILY SSF53474 5 306 4.46E-46 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS20235 880616b51de978b43b93e71c1709cecc 319 Gene3D G3DSA:3.40.50.1820 9 303 3.7E-55 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS20235 880616b51de978b43b93e71c1709cecc 319 PIRSF PIRSF037442 1 304 2.4E-40 T 13-09-2016 IPR017208 Uncharacterised conserved protein UCP037442, alpha/beta hydrolase, RSp0795 THL1_RS20235 880616b51de978b43b93e71c1709cecc 319 Pfam PF12146 Serine aminopeptidase, S33 26 289 7.4E-68 T 13-09-2016 IPR022742 Serine aminopeptidase, S33 THL1_RS19825 f3b7f8588fdd203ca567021de023b579 282 SUPERFAMILY SSF46894 211 278 2.62E-16 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS19825 f3b7f8588fdd203ca567021de023b579 282 Gene3D G3DSA:1.10.10.10 220 278 1.8E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19825 f3b7f8588fdd203ca567021de023b579 282 PANTHER PTHR26402 222 280 1.9E-17 T 13-09-2016 THL1_RS19825 f3b7f8588fdd203ca567021de023b579 282 PANTHER PTHR26402:SF572 222 280 1.9E-17 T 13-09-2016 THL1_RS19825 f3b7f8588fdd203ca567021de023b579 282 SMART SM00421 219 276 4.2E-15 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS19825 f3b7f8588fdd203ca567021de023b579 282 Pfam PF00196 Bacterial regulatory proteins, luxR family 221 274 1.6E-14 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS19825 f3b7f8588fdd203ca567021de023b579 282 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 236 252 1.3E-9 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS19825 f3b7f8588fdd203ca567021de023b579 282 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 222 236 1.3E-9 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS19825 f3b7f8588fdd203ca567021de023b579 282 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 252 264 1.3E-9 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07305 4dbe18fb2df11c0e7d0f2e8db34e1c62 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 1.9E-9 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS07305 4dbe18fb2df11c0e7d0f2e8db34e1c62 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 1.9E-9 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS07305 4dbe18fb2df11c0e7d0f2e8db34e1c62 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 1.9E-9 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS07305 4dbe18fb2df11c0e7d0f2e8db34e1c62 277 Pfam PF00561 alpha/beta hydrolase fold 23 247 5.0E-28 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS07305 4dbe18fb2df11c0e7d0f2e8db34e1c62 277 PRINTS PR00412 Epoxide hydrolase signature 105 118 7.2E-7 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS07305 4dbe18fb2df11c0e7d0f2e8db34e1c62 277 PRINTS PR00412 Epoxide hydrolase signature 239 261 7.2E-7 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS07305 4dbe18fb2df11c0e7d0f2e8db34e1c62 277 PRINTS PR00412 Epoxide hydrolase signature 47 62 7.2E-7 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS07305 4dbe18fb2df11c0e7d0f2e8db34e1c62 277 SUPERFAMILY SSF53474 14 263 1.03E-62 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS07305 4dbe18fb2df11c0e7d0f2e8db34e1c62 277 PANTHER PTHR10992 15 264 2.1E-56 T 13-09-2016 THL1_RS07305 4dbe18fb2df11c0e7d0f2e8db34e1c62 277 Gene3D G3DSA:3.40.50.1820 14 264 5.9E-66 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS09620 ccc9ea2d89c0df3d4455dc6d1fd2efaa 348 Gene3D G3DSA:1.25.40.10 45 311 1.2E-42 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS09620 ccc9ea2d89c0df3d4455dc6d1fd2efaa 348 SUPERFAMILY SSF48452 51 315 4.14E-33 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS09620 ccc9ea2d89c0df3d4455dc6d1fd2efaa 348 PANTHER PTHR23083 173 318 1.3E-36 T 13-09-2016 THL1_RS09620 ccc9ea2d89c0df3d4455dc6d1fd2efaa 348 PANTHER PTHR23083 47 150 1.3E-36 T 13-09-2016 THL1_RS09620 ccc9ea2d89c0df3d4455dc6d1fd2efaa 348 Pfam PF13432 Tetratricopeptide repeat 248 303 4.2E-8 T 13-09-2016 THL1_RS09620 ccc9ea2d89c0df3d4455dc6d1fd2efaa 348 Pfam PF13432 Tetratricopeptide repeat 60 109 1.7E-4 T 13-09-2016 THL1_RS09620 ccc9ea2d89c0df3d4455dc6d1fd2efaa 348 SMART SM00028 271 304 0.08 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS09620 ccc9ea2d89c0df3d4455dc6d1fd2efaa 348 SMART SM00028 207 240 0.0054 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS09620 ccc9ea2d89c0df3d4455dc6d1fd2efaa 348 SMART SM00028 83 116 58.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS09620 ccc9ea2d89c0df3d4455dc6d1fd2efaa 348 SMART SM00028 49 82 51.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS09620 ccc9ea2d89c0df3d4455dc6d1fd2efaa 348 SMART SM00028 173 206 29.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS04075 a50963a69057c0c30fc4ab8dd0af0f37 251 PIRSF PIRSF003073 1 250 1.7E-74 T 13-09-2016 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein THL1_RS04075 a50963a69057c0c30fc4ab8dd0af0f37 251 SMART SM00382 98 229 1.2E-5 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS04075 a50963a69057c0c30fc4ab8dd0af0f37 251 Gene3D G3DSA:3.40.50.300 53 228 1.1E-26 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04075 a50963a69057c0c30fc4ab8dd0af0f37 251 Pfam PF01695 IstB-like ATP binding protein 53 229 1.1E-64 T 13-09-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 THL1_RS04075 a50963a69057c0c30fc4ab8dd0af0f37 251 SUPERFAMILY SSF52540 64 240 4.69E-26 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04075 a50963a69057c0c30fc4ab8dd0af0f37 251 PANTHER PTHR30050:SF6 8 243 4.3E-81 T 13-09-2016 THL1_RS04075 a50963a69057c0c30fc4ab8dd0af0f37 251 PANTHER PTHR30050 8 243 4.3E-81 T 13-09-2016 THL1_RS04075 a50963a69057c0c30fc4ab8dd0af0f37 251 Pfam PF08483 IstB-like ATP binding N-terminal 24 52 2.7E-13 T 13-09-2016 IPR013690 IstB-like ATP binding N-terminal THL1_RS08870 a50963a69057c0c30fc4ab8dd0af0f37 251 PIRSF PIRSF003073 1 250 1.7E-74 T 13-09-2016 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein THL1_RS08870 a50963a69057c0c30fc4ab8dd0af0f37 251 SMART SM00382 98 229 1.2E-5 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS08870 a50963a69057c0c30fc4ab8dd0af0f37 251 Gene3D G3DSA:3.40.50.300 53 228 1.1E-26 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08870 a50963a69057c0c30fc4ab8dd0af0f37 251 Pfam PF01695 IstB-like ATP binding protein 53 229 1.1E-64 T 13-09-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 THL1_RS08870 a50963a69057c0c30fc4ab8dd0af0f37 251 SUPERFAMILY SSF52540 64 240 4.69E-26 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08870 a50963a69057c0c30fc4ab8dd0af0f37 251 PANTHER PTHR30050:SF6 8 243 4.3E-81 T 13-09-2016 THL1_RS08870 a50963a69057c0c30fc4ab8dd0af0f37 251 PANTHER PTHR30050 8 243 4.3E-81 T 13-09-2016 THL1_RS08870 a50963a69057c0c30fc4ab8dd0af0f37 251 Pfam PF08483 IstB-like ATP binding N-terminal 24 52 2.7E-13 T 13-09-2016 IPR013690 IstB-like ATP binding N-terminal THL1_RS26930 a50963a69057c0c30fc4ab8dd0af0f37 251 PIRSF PIRSF003073 1 250 1.7E-74 T 13-09-2016 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein THL1_RS26930 a50963a69057c0c30fc4ab8dd0af0f37 251 SMART SM00382 98 229 1.2E-5 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS26930 a50963a69057c0c30fc4ab8dd0af0f37 251 Gene3D G3DSA:3.40.50.300 53 228 1.1E-26 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26930 a50963a69057c0c30fc4ab8dd0af0f37 251 Pfam PF01695 IstB-like ATP binding protein 53 229 1.1E-64 T 13-09-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 THL1_RS26930 a50963a69057c0c30fc4ab8dd0af0f37 251 SUPERFAMILY SSF52540 64 240 4.69E-26 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26930 a50963a69057c0c30fc4ab8dd0af0f37 251 PANTHER PTHR30050:SF6 8 243 4.3E-81 T 13-09-2016 THL1_RS26930 a50963a69057c0c30fc4ab8dd0af0f37 251 PANTHER PTHR30050 8 243 4.3E-81 T 13-09-2016 THL1_RS26930 a50963a69057c0c30fc4ab8dd0af0f37 251 Pfam PF08483 IstB-like ATP binding N-terminal 24 52 2.7E-13 T 13-09-2016 IPR013690 IstB-like ATP binding N-terminal THL1_RS12510 eda2831b932ad8494a2116c0a03a56f7 69 PRINTS PR00050 Cold shock protein signature 27 36 2.1E-16 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS12510 eda2831b932ad8494a2116c0a03a56f7 69 PRINTS PR00050 Cold shock protein signature 42 60 2.1E-16 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS12510 eda2831b932ad8494a2116c0a03a56f7 69 PRINTS PR00050 Cold shock protein signature 7 22 2.1E-16 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS12510 eda2831b932ad8494a2116c0a03a56f7 69 SMART SM00357 6 69 5.9E-28 T 13-09-2016 IPR011129 Cold shock protein GO:0003676 THL1_RS12510 eda2831b932ad8494a2116c0a03a56f7 69 Gene3D G3DSA:2.40.50.140 5 67 8.9E-30 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS12510 eda2831b932ad8494a2116c0a03a56f7 69 SUPERFAMILY SSF50249 2 68 4.5E-23 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS12510 eda2831b932ad8494a2116c0a03a56f7 69 Pfam PF00313 'Cold-shock' DNA-binding domain 6 68 6.7E-28 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS12510 eda2831b932ad8494a2116c0a03a56f7 69 PIRSF PIRSF002599 1 69 2.6E-23 T 13-09-2016 IPR012156 Cold shock, CspA GO:0003676 THL1_RS12510 eda2831b932ad8494a2116c0a03a56f7 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 36 - T 13-09-2016 IPR019844 Cold-shock conserved site THL1_RS12510 eda2831b932ad8494a2116c0a03a56f7 69 PANTHER PTHR11544 1 69 4.2E-38 T 13-09-2016 THL1_RS16660 d9205c565eef3527fd2a3bc69ff8af96 105 SUPERFAMILY SSF46689 4 56 8.42E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS16660 d9205c565eef3527fd2a3bc69ff8af96 105 Pfam PF01527 Transposase 1 49 2.2E-11 T 13-09-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 THL1_RS16660 d9205c565eef3527fd2a3bc69ff8af96 105 Gene3D G3DSA:1.10.10.60 10 55 2.7E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS22475 cd7c644d0dc762a1b53ad172a2e5b218 107 SUPERFAMILY SSF54862 3 104 1.18E-24 T 13-09-2016 THL1_RS22475 cd7c644d0dc762a1b53ad172a2e5b218 107 PANTHER PTHR11938:SF101 1 84 5.8E-53 T 13-09-2016 THL1_RS22475 cd7c644d0dc762a1b53ad172a2e5b218 107 Pfam PF11953 Domain of unknown function (DUF3470) 66 107 8.9E-23 T 13-09-2016 IPR022569 Ferredoxin, C-terminal THL1_RS22475 cd7c644d0dc762a1b53ad172a2e5b218 107 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS22475 cd7c644d0dc762a1b53ad172a2e5b218 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.4E-18 T 13-09-2016 IPR000813 7Fe ferredoxin GO:0009055 THL1_RS22475 cd7c644d0dc762a1b53ad172a2e5b218 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.4E-18 T 13-09-2016 IPR000813 7Fe ferredoxin GO:0009055 THL1_RS22475 cd7c644d0dc762a1b53ad172a2e5b218 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.4E-18 T 13-09-2016 IPR000813 7Fe ferredoxin GO:0009055 THL1_RS22475 cd7c644d0dc762a1b53ad172a2e5b218 107 Gene3D G3DSA:3.30.70.20 4 100 3.4E-22 T 13-09-2016 THL1_RS22475 cd7c644d0dc762a1b53ad172a2e5b218 107 PANTHER PTHR11938 1 84 5.8E-53 T 13-09-2016 THL1_RS22475 cd7c644d0dc762a1b53ad172a2e5b218 107 Pfam PF00037 4Fe-4S binding domain 34 55 4.5E-6 T 13-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THL1_RS11000 b954a278c1f280c43ddfb1c868b6dcc0 115 Pfam PF14333 Domain of unknown function (DUF4389) 10 85 1.9E-29 T 13-09-2016 IPR025498 Protein of unknown function DUF4389 THL1_RS13730 ce273d80a96c1675b4781571957ea0e7 305 TIGRFAM TIGR02297 HpaA: 4-hydroxyphenylacetate catabolism regulatory protein HpaA 7 295 5.6E-132 T 13-09-2016 IPR011983 4-hydroxyphenylacetate catabolism regulatory protein HpaA THL1_RS13730 ce273d80a96c1675b4781571957ea0e7 305 SUPERFAMILY SSF46689 248 295 9.86E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13730 ce273d80a96c1675b4781571957ea0e7 305 PANTHER PTHR11019:SF45 24 301 3.1E-76 T 13-09-2016 THL1_RS13730 ce273d80a96c1675b4781571957ea0e7 305 Gene3D G3DSA:2.60.120.280 40 177 1.2E-9 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS13730 ce273d80a96c1675b4781571957ea0e7 305 Gene3D G3DSA:1.10.10.60 248 296 2.4E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13730 ce273d80a96c1675b4781571957ea0e7 305 PANTHER PTHR11019 24 301 3.1E-76 T 13-09-2016 THL1_RS13730 ce273d80a96c1675b4781571957ea0e7 305 Pfam PF02311 AraC-like ligand binding domain 34 167 2.4E-12 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS13730 ce273d80a96c1675b4781571957ea0e7 305 SUPERFAMILY SSF51182 40 153 5.16E-10 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS13730 ce273d80a96c1675b4781571957ea0e7 305 SMART SM00342 210 293 5.1E-19 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS13730 ce273d80a96c1675b4781571957ea0e7 305 Pfam PF12833 Helix-turn-helix domain 216 295 1.5E-17 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 499 567 7.7E-8 T 13-09-2016 IPR010221 VCBS repeat THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 874 939 1.7E-4 T 13-09-2016 IPR010221 VCBS repeat THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 243 309 4.2E-8 T 13-09-2016 IPR010221 VCBS repeat THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 TIGRFAM TIGR03661 T1SS_VCA0849: type I secretion C-terminal target domain (VC_A0849 subclass) 2245 2332 3.3E-15 T 13-09-2016 IPR019960 Type I secretion C-terminal target domain, VC_A0849 subclass THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 SMART SM00327 1252 1436 2.6E-15 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 PRINTS PR00313 NodO calcium binding signature 2218 2226 1.6E-5 T 13-09-2016 THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 PRINTS PR00313 NodO calcium binding signature 2147 2155 1.6E-5 T 13-09-2016 THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 PRINTS PR00313 NodO calcium binding signature 2126 2137 1.6E-5 T 13-09-2016 THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 PRINTS PR00313 NodO calcium binding signature 2227 2236 1.6E-5 T 13-09-2016 THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 Pfam PF00092 von Willebrand factor type A domain 1254 1429 3.3E-11 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 Gene3D G3DSA:2.150.10.10 1452 1483 5.4E-12 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 Gene3D G3DSA:2.150.10.10 1631 1645 5.4E-12 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 Gene3D G3DSA:2.150.10.10 2120 2162 5.4E-12 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 Gene3D G3DSA:2.150.10.10 2198 2293 5.4E-12 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 Gene3D G3DSA:3.40.50.410 1252 1439 3.0E-14 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 SUPERFAMILY SSF51120 2184 2309 8.11E-16 T 13-09-2016 IPR011049 Serralysin-like metalloprotease, C-terminal THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2134 2152 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 SUPERFAMILY SSF53300 1251 1434 1.46E-21 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS09345 72e3a46f0eadf8f64361c508ac2648d3 2335 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 2143 2161 - T 13-09-2016 IPR018511 Hemolysin-type calcium-binding conserved site THL1_RS23090 772229949d524efcad8542ef65c90a8b 457 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 13-09-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 THL1_RS23090 772229949d524efcad8542ef65c90a8b 457 SMART SM00962 100 296 2.9E-116 T 13-09-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 THL1_RS23090 772229949d524efcad8542ef65c90a8b 457 Gene3D G3DSA:1.20.120.140 2 88 2.6E-35 T 13-09-2016 THL1_RS23090 772229949d524efcad8542ef65c90a8b 457 SUPERFAMILY SSF47446 329 433 3.92E-35 T 13-09-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 THL1_RS23090 772229949d524efcad8542ef65c90a8b 457 PANTHER PTHR11564:SF7 1 439 1.4E-268 T 13-09-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 THL1_RS23090 772229949d524efcad8542ef65c90a8b 457 SUPERFAMILY SSF52540 42 355 9.91E-60 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS23090 772229949d524efcad8542ef65c90a8b 457 SMART SM00963 1 86 7.2E-35 T 13-09-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 THL1_RS23090 772229949d524efcad8542ef65c90a8b 457 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 432 3.7E-179 T 13-09-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 THL1_RS23090 772229949d524efcad8542ef65c90a8b 457 Gene3D G3DSA:1.10.260.30 329 434 1.1E-38 T 13-09-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 THL1_RS23090 772229949d524efcad8542ef65c90a8b 457 Pfam PF02978 Signal peptide binding domain 329 430 5.0E-33 T 13-09-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 THL1_RS23090 772229949d524efcad8542ef65c90a8b 457 Pfam PF00448 SRP54-type protein, GTPase domain 100 296 2.1E-75 T 13-09-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 THL1_RS23090 772229949d524efcad8542ef65c90a8b 457 PANTHER PTHR11564 1 439 1.4E-268 T 13-09-2016 THL1_RS23090 772229949d524efcad8542ef65c90a8b 457 SMART SM00382 99 247 7.9E-9 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS23090 772229949d524efcad8542ef65c90a8b 457 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 443 34.572 T 13-09-2016 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 THL1_RS23090 772229949d524efcad8542ef65c90a8b 457 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 1.5E-20 T 13-09-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 THL1_RS23090 772229949d524efcad8542ef65c90a8b 457 Gene3D G3DSA:3.40.50.300 96 297 1.1E-77 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27015 c55e372fd8b797b4585d50e9402d44cb 310 SUPERFAMILY SSF53633 1 300 4.19E-79 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS27015 c55e372fd8b797b4585d50e9402d44cb 310 PIRSF PIRSF000723 1 302 2.2E-112 T 13-09-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 THL1_RS27015 c55e372fd8b797b4585d50e9402d44cb 310 PRINTS PR01469 Bacterial carbamate kinase signature 174 192 3.5E-70 T 13-09-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 THL1_RS27015 c55e372fd8b797b4585d50e9402d44cb 310 PRINTS PR01469 Bacterial carbamate kinase signature 257 272 3.5E-70 T 13-09-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 THL1_RS27015 c55e372fd8b797b4585d50e9402d44cb 310 PRINTS PR01469 Bacterial carbamate kinase signature 206 221 3.5E-70 T 13-09-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 THL1_RS27015 c55e372fd8b797b4585d50e9402d44cb 310 PRINTS PR01469 Bacterial carbamate kinase signature 103 122 3.5E-70 T 13-09-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 THL1_RS27015 c55e372fd8b797b4585d50e9402d44cb 310 PRINTS PR01469 Bacterial carbamate kinase signature 41 60 3.5E-70 T 13-09-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 THL1_RS27015 c55e372fd8b797b4585d50e9402d44cb 310 PRINTS PR01469 Bacterial carbamate kinase signature 151 170 3.5E-70 T 13-09-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 THL1_RS27015 c55e372fd8b797b4585d50e9402d44cb 310 PRINTS PR01469 Bacterial carbamate kinase signature 71 89 3.5E-70 T 13-09-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 THL1_RS27015 c55e372fd8b797b4585d50e9402d44cb 310 TIGRFAM TIGR00746 arcC: carbamate kinase 1 301 3.6E-136 T 13-09-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 THL1_RS27015 c55e372fd8b797b4585d50e9402d44cb 310 Gene3D G3DSA:3.40.1160.10 1 301 1.8E-98 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS27015 c55e372fd8b797b4585d50e9402d44cb 310 PANTHER PTHR30409 1 303 9.7E-155 T 13-09-2016 THL1_RS27015 c55e372fd8b797b4585d50e9402d44cb 310 Pfam PF00696 Amino acid kinase family 1 283 1.0E-26 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS27015 c55e372fd8b797b4585d50e9402d44cb 310 PANTHER PTHR30409:SF1 1 303 9.7E-155 T 13-09-2016 THL1_RS09625 edddca36ab7017441ee75f543bae05b6 93 PRINTS PR01727 Prokaryotic integration host factor signature 60 73 1.1E-11 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS09625 edddca36ab7017441ee75f543bae05b6 93 PRINTS PR01727 Prokaryotic integration host factor signature 42 57 1.1E-11 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS09625 edddca36ab7017441ee75f543bae05b6 93 PRINTS PR01727 Prokaryotic integration host factor signature 76 90 1.1E-11 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS09625 edddca36ab7017441ee75f543bae05b6 93 Gene3D G3DSA:4.10.520.10 2 93 1.8E-31 T 13-09-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THL1_RS09625 edddca36ab7017441ee75f543bae05b6 93 SMART SM00411 3 92 2.8E-33 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS09625 edddca36ab7017441ee75f543bae05b6 93 Pfam PF00216 Bacterial DNA-binding protein 4 92 1.5E-29 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS09625 edddca36ab7017441ee75f543bae05b6 93 PANTHER PTHR33175 2 92 1.6E-34 T 13-09-2016 THL1_RS09625 edddca36ab7017441ee75f543bae05b6 93 SUPERFAMILY SSF47729 3 92 1.34E-28 T 13-09-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THL1_RS07155 3ceab0f64c4306078d51e8db22201e43 263 PANTHER PTHR30143 7 261 2.4E-78 T 13-09-2016 THL1_RS07155 3ceab0f64c4306078d51e8db22201e43 263 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 86 259 7.2E-11 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS07155 3ceab0f64c4306078d51e8db22201e43 263 SUPERFAMILY SSF56529 1 261 1.83E-77 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS07155 3ceab0f64c4306078d51e8db22201e43 263 Gene3D G3DSA:3.90.850.10 6 261 1.1E-83 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS13010 a5f9702483c8d7b4f687c4aa039ca133 138 SUPERFAMILY SSF54637 6 135 7.47E-23 T 13-09-2016 IPR029069 HotDog domain THL1_RS13010 a5f9702483c8d7b4f687c4aa039ca133 138 Pfam PF03061 Thioesterase superfamily 45 119 5.2E-12 T 13-09-2016 IPR006683 Thioesterase domain THL1_RS13010 a5f9702483c8d7b4f687c4aa039ca133 138 Gene3D G3DSA:3.10.129.10 7 135 1.3E-37 T 13-09-2016 IPR029069 HotDog domain THL1_RS13010 a5f9702483c8d7b4f687c4aa039ca133 138 PANTHER PTHR12418:SF30 23 133 1.9E-39 T 13-09-2016 THL1_RS13010 a5f9702483c8d7b4f687c4aa039ca133 138 PANTHER PTHR12418 23 133 1.9E-39 T 13-09-2016 THL1_RS16470 ee355bf411297fbb9d61f9b072b98f90 566 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 408 561 1.0E-15 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS16470 ee355bf411297fbb9d61f9b072b98f90 566 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 286 9.4E-13 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS16470 ee355bf411297fbb9d61f9b072b98f90 566 SUPERFAMILY SSF161098 312 564 3.66E-46 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS16470 ee355bf411297fbb9d61f9b072b98f90 566 SUPERFAMILY SSF161098 30 285 4.21E-47 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS16470 ee355bf411297fbb9d61f9b072b98f90 566 PANTHER PTHR30193 31 301 1.5E-69 T 13-09-2016 THL1_RS16470 ee355bf411297fbb9d61f9b072b98f90 566 Gene3D G3DSA:1.10.3720.10 28 291 4.1E-42 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS16470 ee355bf411297fbb9d61f9b072b98f90 566 Gene3D G3DSA:1.10.3720.10 315 565 4.4E-48 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS16470 ee355bf411297fbb9d61f9b072b98f90 566 PANTHER PTHR30193:SF10 31 301 1.5E-69 T 13-09-2016 THL1_RS14730 ee1790e7f6ebf00d98bf8a811c68a3b0 447 Pfam PF07690 Major Facilitator Superfamily 66 392 6.2E-33 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS14730 ee1790e7f6ebf00d98bf8a811c68a3b0 447 PANTHER PTHR23508 8 437 4.0E-160 T 13-09-2016 THL1_RS14730 ee1790e7f6ebf00d98bf8a811c68a3b0 447 Gene3D G3DSA:1.20.1250.20 248 434 2.2E-21 T 13-09-2016 THL1_RS14730 ee1790e7f6ebf00d98bf8a811c68a3b0 447 Gene3D G3DSA:1.20.1250.20 25 230 3.7E-21 T 13-09-2016 THL1_RS14730 ee1790e7f6ebf00d98bf8a811c68a3b0 447 SUPERFAMILY SSF103473 21 433 9.02E-65 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS14730 ee1790e7f6ebf00d98bf8a811c68a3b0 447 PANTHER PTHR23508:SF1 8 437 4.0E-160 T 13-09-2016 THL1_RS04755 3b2c81532d4221a4f9349d8497cc8f6d 555 PANTHER PTHR19211:SF7 1 555 0.0 T 13-09-2016 THL1_RS04755 3b2c81532d4221a4f9349d8497cc8f6d 555 SUPERFAMILY SSF52540 12 243 1.92E-46 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04755 3b2c81532d4221a4f9349d8497cc8f6d 555 SUPERFAMILY SSF52540 301 530 4.78E-46 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04755 3b2c81532d4221a4f9349d8497cc8f6d 555 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS04755 3b2c81532d4221a4f9349d8497cc8f6d 555 PANTHER PTHR19211 1 555 0.0 T 13-09-2016 THL1_RS04755 3b2c81532d4221a4f9349d8497cc8f6d 555 Gene3D G3DSA:3.40.50.300 141 288 2.4E-47 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04755 3b2c81532d4221a4f9349d8497cc8f6d 555 Gene3D G3DSA:3.40.50.300 11 105 2.4E-47 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04755 3b2c81532d4221a4f9349d8497cc8f6d 555 Pfam PF00005 ABC transporter 340 473 1.5E-21 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS04755 3b2c81532d4221a4f9349d8497cc8f6d 555 Pfam PF00005 ABC transporter 22 191 5.2E-27 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS04755 3b2c81532d4221a4f9349d8497cc8f6d 555 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 553 8.2E-294 T 13-09-2016 IPR022374 ABC transporter, ATP-binding protein, ChvD THL1_RS04755 3b2c81532d4221a4f9349d8497cc8f6d 555 Gene3D G3DSA:3.40.50.300 322 537 1.0E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04755 3b2c81532d4221a4f9349d8497cc8f6d 555 Pfam PF12848 ABC transporter 230 305 2.2E-10 T 13-09-2016 IPR032781 ABC-transporter extension domain THL1_RS04755 3b2c81532d4221a4f9349d8497cc8f6d 555 SMART SM00382 31 240 1.8E-8 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS04755 3b2c81532d4221a4f9349d8497cc8f6d 555 SMART SM00382 348 522 4.7E-9 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS16345 3cd49791335cae4d10bc54ba80e96be6 109 Gene3D G3DSA:1.10.10.10 13 82 1.9E-7 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS16345 3cd49791335cae4d10bc54ba80e96be6 109 SUPERFAMILY SSF46785 16 83 4.68E-9 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS05955 b81e5f5c358aad4a767facbcad2a0791 112 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 91 7.5E-17 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS05955 b81e5f5c358aad4a767facbcad2a0791 112 SUPERFAMILY SSF54292 4 106 1.66E-33 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS05955 b81e5f5c358aad4a767facbcad2a0791 112 Gene3D G3DSA:3.10.20.30 5 106 1.1E-34 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS05955 b81e5f5c358aad4a767facbcad2a0791 112 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 13-09-2016 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 THL1_RS05955 b81e5f5c358aad4a767facbcad2a0791 112 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 110 1.8E-57 T 13-09-2016 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 THL1_RS05955 b81e5f5c358aad4a767facbcad2a0791 112 PANTHER PTHR23426 7 112 5.6E-42 T 13-09-2016 THL1_RS05955 b81e5f5c358aad4a767facbcad2a0791 112 PRINTS PR00355 Adrenodoxin signature 42 52 2.3E-9 T 13-09-2016 IPR001055 Adrenodoxin GO:0009055|GO:0051537 THL1_RS05955 b81e5f5c358aad4a767facbcad2a0791 112 PRINTS PR00355 Adrenodoxin signature 60 74 2.3E-9 T 13-09-2016 IPR001055 Adrenodoxin GO:0009055|GO:0051537 THL1_RS05955 b81e5f5c358aad4a767facbcad2a0791 112 PRINTS PR00355 Adrenodoxin signature 83 91 2.3E-9 T 13-09-2016 IPR001055 Adrenodoxin GO:0009055|GO:0051537 THL1_RS07605 d92528e89e5c2bf85b19b0c02de5004c 383 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS07605 d92528e89e5c2bf85b19b0c02de5004c 383 Gene3D G3DSA:2.40.50.100 348 362 4.0E-8 T 13-09-2016 THL1_RS07605 d92528e89e5c2bf85b19b0c02de5004c 383 Gene3D G3DSA:2.40.50.100 241 288 4.0E-8 T 13-09-2016 THL1_RS07605 d92528e89e5c2bf85b19b0c02de5004c 383 SUPERFAMILY SSF50331 238 362 3.64E-26 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS07605 d92528e89e5c2bf85b19b0c02de5004c 383 SMART SM00382 30 221 7.2E-15 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS07605 d92528e89e5c2bf85b19b0c02de5004c 383 Gene3D G3DSA:3.40.50.300 3 235 2.8E-78 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07605 d92528e89e5c2bf85b19b0c02de5004c 383 Pfam PF08402 TOBE domain 284 354 1.5E-8 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS07605 d92528e89e5c2bf85b19b0c02de5004c 383 Pfam PF00005 ABC transporter 21 163 7.1E-32 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS07605 d92528e89e5c2bf85b19b0c02de5004c 383 PANTHER PTHR24220:SF446 5 294 1.0E-190 T 13-09-2016 THL1_RS07605 d92528e89e5c2bf85b19b0c02de5004c 383 SUPERFAMILY SSF52540 4 245 1.44E-85 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07605 d92528e89e5c2bf85b19b0c02de5004c 383 Gene3D G3DSA:2.40.50.140 289 346 5.7E-12 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS07605 d92528e89e5c2bf85b19b0c02de5004c 383 PANTHER PTHR24220 5 294 1.0E-190 T 13-09-2016 THL1_RS04325 51d203fae69d724cf8bbe82bc2c79c76 446 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 440 1.2E-184 T 13-09-2016 THL1_RS04325 51d203fae69d724cf8bbe82bc2c79c76 446 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 438 2.0E-147 T 13-09-2016 IPR005839 Methylthiotransferase GO:0016740|GO:0043412|GO:0051539 THL1_RS04325 51d203fae69d724cf8bbe82bc2c79c76 446 PANTHER PTHR11918:SF43 1 443 9.5E-202 T 13-09-2016 THL1_RS04325 51d203fae69d724cf8bbe82bc2c79c76 446 Pfam PF04055 Radical SAM superfamily 151 325 4.0E-28 T 13-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 THL1_RS04325 51d203fae69d724cf8bbe82bc2c79c76 446 Pfam PF01938 TRAM domain 378 441 3.7E-19 T 13-09-2016 IPR002792 TRAM domain THL1_RS04325 51d203fae69d724cf8bbe82bc2c79c76 446 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 151 171 - T 13-09-2016 IPR020612 Methylthiotransferase, conserved site GO:0051539 THL1_RS04325 51d203fae69d724cf8bbe82bc2c79c76 446 Gene3D G3DSA:3.80.30.20 146 380 4.1E-75 T 13-09-2016 IPR023404 Radical SAM, alpha/beta horseshoe THL1_RS04325 51d203fae69d724cf8bbe82bc2c79c76 446 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 3 442 72.417 T 13-09-2016 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 THL1_RS04325 51d203fae69d724cf8bbe82bc2c79c76 446 SUPERFAMILY SSF102114 125 375 5.62E-59 T 13-09-2016 THL1_RS04325 51d203fae69d724cf8bbe82bc2c79c76 446 PANTHER PTHR11918 1 443 9.5E-202 T 13-09-2016 IPR023970 Methylthiotransferase/radical SAM-type protein THL1_RS04325 51d203fae69d724cf8bbe82bc2c79c76 446 SMART SM00729 147 367 4.0E-54 T 13-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THL1_RS04325 51d203fae69d724cf8bbe82bc2c79c76 446 Pfam PF00919 Uncharacterized protein family UPF0004 4 104 9.8E-29 T 13-09-2016 IPR013848 Methylthiotransferase, N-terminal GO:0003824|GO:0009451|GO:0051539 THL1_RS18435 1a9e164dc2435ba429e458da5d5b5a70 574 PANTHER PTHR10166 204 445 1.7E-104 T 13-09-2016 THL1_RS18435 1a9e164dc2435ba429e458da5d5b5a70 574 Pfam PF00092 von Willebrand factor type A domain 207 371 3.8E-21 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS18435 1a9e164dc2435ba429e458da5d5b5a70 574 Gene3D G3DSA:3.40.50.410 204 379 6.7E-26 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS18435 1a9e164dc2435ba429e458da5d5b5a70 574 Pfam PF12450 von Willebrand factor 100 190 3.3E-38 T 13-09-2016 IPR022156 Uncharacterised protein YfbK, N-terminal THL1_RS18435 1a9e164dc2435ba429e458da5d5b5a70 574 SMART SM00327 205 382 9.8E-28 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS18435 1a9e164dc2435ba429e458da5d5b5a70 574 Pfam PF12034 Domain of unknown function (DUF3520) 383 563 7.4E-68 T 13-09-2016 IPR021908 Protein of unknown function DUF3520 THL1_RS18435 1a9e164dc2435ba429e458da5d5b5a70 574 SUPERFAMILY SSF53300 204 376 1.83E-37 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS18435 1a9e164dc2435ba429e458da5d5b5a70 574 PANTHER PTHR10166:SF15 204 445 1.7E-104 T 13-09-2016 THL1_RS13390 696fbb92c391502be5bb4b160c85ab58 254 SUPERFAMILY SSF51735 6 251 2.52E-83 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS13390 696fbb92c391502be5bb4b160c85ab58 254 PANTHER PTHR24321 2 251 6.6E-62 T 13-09-2016 THL1_RS13390 696fbb92c391502be5bb4b160c85ab58 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 4.6E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13390 696fbb92c391502be5bb4b160c85ab58 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.6E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13390 696fbb92c391502be5bb4b160c85ab58 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 4.6E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13390 696fbb92c391502be5bb4b160c85ab58 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.6E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13390 696fbb92c391502be5bb4b160c85ab58 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.6E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13390 696fbb92c391502be5bb4b160c85ab58 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 4.6E-43 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13390 696fbb92c391502be5bb4b160c85ab58 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.4E-8 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13390 696fbb92c391502be5bb4b160c85ab58 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.4E-8 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13390 696fbb92c391502be5bb4b160c85ab58 254 PANTHER PTHR24321:SF6 2 251 6.6E-62 T 13-09-2016 THL1_RS13390 696fbb92c391502be5bb4b160c85ab58 254 Gene3D G3DSA:3.40.50.720 1 251 1.8E-86 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS13390 696fbb92c391502be5bb4b160c85ab58 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 249 9.7E-71 T 13-09-2016 THL1_RS26400 887579b9189ed74ebbe728740b1e1ae7 204 Pfam PF13972 Bacterial transcriptional repressor 56 192 2.3E-32 T 13-09-2016 IPR025722 Bacterial transcriptional repressor TetR THL1_RS26400 887579b9189ed74ebbe728740b1e1ae7 204 SUPERFAMILY SSF46689 2 71 3.9E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS26400 887579b9189ed74ebbe728740b1e1ae7 204 PANTHER PTHR30055 1 188 1.4E-49 T 13-09-2016 THL1_RS26400 887579b9189ed74ebbe728740b1e1ae7 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 52 3.9E-11 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS26400 887579b9189ed74ebbe728740b1e1ae7 204 PANTHER PTHR30055:SF30 1 188 1.4E-49 T 13-09-2016 THL1_RS26400 887579b9189ed74ebbe728740b1e1ae7 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 6.8E-9 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS26400 887579b9189ed74ebbe728740b1e1ae7 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 6.8E-9 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS26400 887579b9189ed74ebbe728740b1e1ae7 204 Gene3D G3DSA:1.10.357.10 2 188 1.4E-28 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 17 320 41.458 T 13-09-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 18 162 3.0E-37 T 13-09-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 64 71 - T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 18 318 1.3E-88 T 13-09-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 PANTHER PTHR11405 1 316 2.6E-131 T 13-09-2016 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 SUPERFAMILY SSF53671 17 319 2.23E-94 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 PANTHER PTHR11405:SF16 1 316 2.6E-131 T 13-09-2016 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 170 315 3.3E-22 T 13-09-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 150 161 7.7E-18 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 64 83 7.7E-18 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 271 280 7.7E-18 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 283 306 7.7E-18 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 PRINTS PR00101 Aspartate carbamoyltransferase signature 54 76 2.9E-31 T 13-09-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 PRINTS PR00101 Aspartate carbamoyltransferase signature 299 313 2.9E-31 T 13-09-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 PRINTS PR00101 Aspartate carbamoyltransferase signature 149 166 2.9E-31 T 13-09-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 PRINTS PR00101 Aspartate carbamoyltransferase signature 275 280 2.9E-31 T 13-09-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 PRINTS PR00101 Aspartate carbamoyltransferase signature 92 101 2.9E-31 T 13-09-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 PRINTS PR00101 Aspartate carbamoyltransferase signature 234 243 2.9E-31 T 13-09-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 Gene3D G3DSA:3.40.50.1370 18 161 2.5E-50 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS01490 98e63d9a1ef75d298deb8682037ec430 335 Gene3D G3DSA:3.40.50.1370 162 297 7.8E-47 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS15710 255a9594905a3625dea1b21c2728db5e 149 SUPERFAMILY SSF54637 8 132 2.49E-31 T 13-09-2016 IPR029069 HotDog domain THL1_RS15710 255a9594905a3625dea1b21c2728db5e 149 PANTHER PTHR12418 18 149 1.9E-39 T 13-09-2016 THL1_RS15710 255a9594905a3625dea1b21c2728db5e 149 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 25 137 1.9E-49 T 13-09-2016 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 KEGG: 00360+3.1.2.-|KEGG: 00362+3.1.2.-|KEGG: 00592+3.1.2.-|KEGG: 00903+3.1.2.- THL1_RS15710 255a9594905a3625dea1b21c2728db5e 149 Pfam PF03061 Thioesterase superfamily 53 127 1.3E-15 T 13-09-2016 IPR006683 Thioesterase domain THL1_RS15710 255a9594905a3625dea1b21c2728db5e 149 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 24 134 2.8E-23 T 13-09-2016 IPR003736 Phenylacetic acid degradation-related domain THL1_RS15710 255a9594905a3625dea1b21c2728db5e 149 Gene3D G3DSA:3.10.129.10 10 146 3.5E-45 T 13-09-2016 IPR029069 HotDog domain THL1_RS15710 255a9594905a3625dea1b21c2728db5e 149 PANTHER PTHR12418:SF24 18 149 1.9E-39 T 13-09-2016 THL1_RS25870 a3ad4de4a039a238ac0d93d577c48bce 626 Gene3D G3DSA:3.30.565.10 6 216 1.8E-75 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS25870 a3ad4de4a039a238ac0d93d577c48bce 626 SMART SM00853 439 582 1.0E-57 T 13-09-2016 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 THL1_RS25870 a3ad4de4a039a238ac0d93d577c48bce 626 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 97 103 - T 13-09-2016 IPR014762 DNA mismatch repair, conserved site THL1_RS25870 a3ad4de4a039a238ac0d93d577c48bce 626 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 6 314 3.9E-101 T 13-09-2016 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 THL1_RS25870 a3ad4de4a039a238ac0d93d577c48bce 626 Pfam PF08676 MutL C terminal dimerisation domain 435 582 4.4E-52 T 13-09-2016 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 THL1_RS25870 a3ad4de4a039a238ac0d93d577c48bce 626 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 5 622 30.047 T 13-09-2016 IPR020667 DNA mismatch repair protein, MutL GO:0006298 THL1_RS25870 a3ad4de4a039a238ac0d93d577c48bce 626 PANTHER PTHR10073 7 622 4.4E-175 T 13-09-2016 THL1_RS25870 a3ad4de4a039a238ac0d93d577c48bce 626 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 130 2.1E-10 T 13-09-2016 THL1_RS25870 a3ad4de4a039a238ac0d93d577c48bce 626 SUPERFAMILY SSF54211 195 334 1.14E-40 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS25870 a3ad4de4a039a238ac0d93d577c48bce 626 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 217 333 2.6E-40 T 13-09-2016 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 THL1_RS25870 a3ad4de4a039a238ac0d93d577c48bce 626 SMART SM01340 216 334 8.1E-63 T 13-09-2016 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 THL1_RS25870 a3ad4de4a039a238ac0d93d577c48bce 626 Gene3D G3DSA:3.30.230.10 222 333 3.7E-40 T 13-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THL1_RS25870 a3ad4de4a039a238ac0d93d577c48bce 626 SUPERFAMILY SSF55874 6 208 1.7E-54 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS25870 a3ad4de4a039a238ac0d93d577c48bce 626 SUPERFAMILY SSF118116 435 624 3.14E-63 T 13-09-2016 THL1_RS16840 96d98bc95e58360044f61850b3048341 90 SUPERFAMILY SSF53720 40 90 6.41E-7 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS16840 96d98bc95e58360044f61850b3048341 90 Gene3D G3DSA:3.40.309.10 40 84 2.8E-5 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS22535 db806dc37f5d282fbf7b07c69ff8b94e 94 PANTHER PTHR37485 7 94 3.1E-42 T 13-09-2016 THL1_RS22535 db806dc37f5d282fbf7b07c69ff8b94e 94 PANTHER PTHR37485:SF1 7 94 3.1E-42 T 13-09-2016 THL1_RS22535 db806dc37f5d282fbf7b07c69ff8b94e 94 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 94 31.538 T 13-09-2016 IPR023081 Cell division protein FtsB THL1_RS22535 db806dc37f5d282fbf7b07c69ff8b94e 94 Pfam PF04977 Septum formation initiator 16 92 7.0E-23 T 13-09-2016 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 Gene3D G3DSA:3.40.50.300 139 302 1.7E-55 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 154 167 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 343 352 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 Gene3D G3DSA:3.40.50.2300 2 138 5.4E-34 T 13-09-2016 THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 Pfam PF02954 Bacterial regulatory protein, Fis family 412 449 6.3E-13 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 Pfam PF00072 Response regulator receiver domain 5 114 2.3E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 SUPERFAMILY SSF46689 343 449 5.82E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 SUPERFAMILY SSF52540 132 371 2.34E-70 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 PANTHER PTHR32071:SF21 1 464 3.8E-258 T 13-09-2016 IPR029995 Transcriptional regulatory protein FlbD GO:0003700|GO:0006355 THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 216 231 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 PANTHER PTHR32071 1 464 3.8E-258 T 13-09-2016 THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 SUPERFAMILY SSF52172 4 174 1.71E-39 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 SMART SM00382 150 293 1.1E-12 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 SMART SM00448 3 114 2.0E-32 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 Gene3D G3DSA:1.10.10.60 357 450 1.2E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 416 433 2.5E-6 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 433 453 2.5E-6 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 Pfam PF00158 Sigma-54 interaction domain 135 296 3.6E-67 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS19620 ae818a611fb094d3b1b8efaef6e46805 464 Gene3D G3DSA:1.10.8.60 303 356 3.5E-23 T 13-09-2016 THL1_RS15405 7e5fa9531cd868de36ea25a295a814b4 175 Gene3D G3DSA:1.10.760.10 52 143 4.4E-5 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS15405 7e5fa9531cd868de36ea25a295a814b4 175 SUPERFAMILY SSF46626 44 124 5.32E-7 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS27480 ce052d8ef94817707d155d1ae813d105 135 PANTHER PTHR30437 7 133 3.5E-62 T 13-09-2016 THL1_RS27480 ce052d8ef94817707d155d1ae813d105 135 Pfam PF14760 Rnk N-terminus 5 44 7.3E-15 T 13-09-2016 IPR029462 Regulator of nucleoside diphosphate kinase, N-terminal domain THL1_RS27480 ce052d8ef94817707d155d1ae813d105 135 Gene3D G3DSA:3.10.50.30 47 135 7.4E-28 T 13-09-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 THL1_RS27480 ce052d8ef94817707d155d1ae813d105 135 SUPERFAMILY SSF54534 49 126 5.23E-16 T 13-09-2016 THL1_RS27480 ce052d8ef94817707d155d1ae813d105 135 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 51 125 4.8E-18 T 13-09-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 THL1_RS27480 ce052d8ef94817707d155d1ae813d105 135 PANTHER PTHR30437:SF5 7 133 3.5E-62 T 13-09-2016 THL1_RS27480 ce052d8ef94817707d155d1ae813d105 135 Gene3D G3DSA:1.10.286.20 1 44 4.8E-19 T 13-09-2016 THL1_RS21170 2fc78206982496ca0b431885648f8003 332 TIGRFAM TIGR03242 arg_catab_astE: succinylglutamate desuccinylase 6 328 2.2E-118 T 13-09-2016 IPR016681 Succinylglutamate desuccinylase GO:0008270|GO:0009017|GO:0019544|GO:0019545 KEGG: 00330+3.5.1.96|UniPathway: UPA00185 THL1_RS21170 2fc78206982496ca0b431885648f8003 332 SUPERFAMILY SSF53187 6 329 2.18E-74 T 13-09-2016 THL1_RS21170 2fc78206982496ca0b431885648f8003 332 PIRSF PIRSF017020 1 332 1.2E-115 T 13-09-2016 IPR016681 Succinylglutamate desuccinylase GO:0008270|GO:0009017|GO:0019544|GO:0019545 KEGG: 00330+3.5.1.96|UniPathway: UPA00185 THL1_RS21170 2fc78206982496ca0b431885648f8003 332 Hamap MF_00767 Succinylglutamate desuccinylase [astE]. 1 332 151.898 T 13-09-2016 IPR016681 Succinylglutamate desuccinylase GO:0008270|GO:0009017|GO:0019544|GO:0019545 KEGG: 00330+3.5.1.96|UniPathway: UPA00185 THL1_RS21170 2fc78206982496ca0b431885648f8003 332 Gene3D G3DSA:3.40.630.10 48 236 2.2E-15 T 13-09-2016 THL1_RS21170 2fc78206982496ca0b431885648f8003 332 PANTHER PTHR15162 1 328 8.5E-79 T 13-09-2016 THL1_RS21170 2fc78206982496ca0b431885648f8003 332 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 49 329 1.2E-70 T 13-09-2016 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 THL1_RS00220 c2b58f83a5b98c5193b334a13ee0c4f2 181 Gene3D G3DSA:2.160.10.10 2 173 3.0E-44 T 13-09-2016 THL1_RS00220 c2b58f83a5b98c5193b334a13ee0c4f2 181 SUPERFAMILY SSF51161 3 174 1.14E-43 T 13-09-2016 IPR011004 Trimeric LpxA-like THL1_RS00220 c2b58f83a5b98c5193b334a13ee0c4f2 181 PANTHER PTHR13061 1 177 8.8E-75 T 13-09-2016 THL1_RS00220 c2b58f83a5b98c5193b334a13ee0c4f2 181 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 96 129 4.6E-7 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS00220 c2b58f83a5b98c5193b334a13ee0c4f2 181 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 13 46 2.3E-5 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS03460 454d5253e09ac099011298e088440c38 122 Gene3D G3DSA:1.20.5.1030 63 121 9.6E-25 T 13-09-2016 THL1_RS03460 454d5253e09ac099011298e088440c38 122 PANTHER PTHR33910:SF1 1 122 7.5E-26 T 13-09-2016 THL1_RS03460 454d5253e09ac099011298e088440c38 122 PRINTS PR01650 Bacterial translocase SecE signature 63 83 6.3E-26 T 13-09-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 THL1_RS03460 454d5253e09ac099011298e088440c38 122 PRINTS PR01650 Bacterial translocase SecE signature 42 63 6.3E-26 T 13-09-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 THL1_RS03460 454d5253e09ac099011298e088440c38 122 PRINTS PR01650 Bacterial translocase SecE signature 87 107 6.3E-26 T 13-09-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 THL1_RS03460 454d5253e09ac099011298e088440c38 122 PRINTS PR01650 Bacterial translocase SecE signature 107 122 6.3E-26 T 13-09-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 THL1_RS03460 454d5253e09ac099011298e088440c38 122 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 69 97 - T 13-09-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 THL1_RS03460 454d5253e09ac099011298e088440c38 122 PANTHER PTHR33910 1 122 7.5E-26 T 13-09-2016 THL1_RS03460 454d5253e09ac099011298e088440c38 122 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 71 120 5.0E-20 T 13-09-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 THL1_RS03460 454d5253e09ac099011298e088440c38 122 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 69 122 7.1E-21 T 13-09-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 THL1_RS03460 454d5253e09ac099011298e088440c38 122 Hamap MF_00422 Protein translocase subunit SecE [secE]. 61 119 13.61 T 13-09-2016 IPR022943 Preprotein translocase subunit SecE THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 357 376 3.6E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 337 345 3.6E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 284 295 3.6E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 215 388 1.9E-6 T 13-09-2016 THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 Gene3D G3DSA:3.40.50.720 209 447 5.4E-68 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 221 444 1.5E-49 T 13-09-2016 THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 PANTHER PTHR24322:SF438 357 388 5.3E-71 T 13-09-2016 THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 PANTHER PTHR24322:SF438 219 341 5.3E-71 T 13-09-2016 THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 411 431 1.4E-31 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 331 347 1.4E-31 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 357 376 1.4E-31 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 284 295 1.4E-31 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 378 395 1.4E-31 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 233 1.4E-31 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 SUPERFAMILY SSF51735 211 449 2.95E-62 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 344 372 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 PANTHER PTHR24322 357 388 5.3E-71 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25170 37410f821a08fa2255e0754659891c2a 451 PANTHER PTHR24322 219 341 5.3E-71 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21550 0f9f9976544825e270e0377ec6572328 228 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 14 219 3.0E-71 T 13-09-2016 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 THL1_RS21550 0f9f9976544825e270e0377ec6572328 228 PANTHER PTHR30183 1 224 5.9E-67 T 13-09-2016 THL1_RS21550 0f9f9976544825e270e0377ec6572328 228 SUPERFAMILY SSF161098 8 219 2.75E-46 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS21550 0f9f9976544825e270e0377ec6572328 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 219 4.3E-16 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS21550 0f9f9976544825e270e0377ec6572328 228 Gene3D G3DSA:1.10.3720.10 10 221 2.5E-39 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS14525 7e9c902473013234f99c225782b886fd 526 PANTHER PTHR11552 13 517 5.3E-98 T 13-09-2016 THL1_RS14525 7e9c902473013234f99c225782b886fd 526 Gene3D G3DSA:3.50.50.60 13 142 2.4E-76 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS14525 7e9c902473013234f99c225782b886fd 526 Gene3D G3DSA:3.50.50.60 201 307 2.4E-76 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS14525 7e9c902473013234f99c225782b886fd 526 Gene3D G3DSA:3.50.50.60 421 517 2.4E-76 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS14525 7e9c902473013234f99c225782b886fd 526 Pfam PF05199 GMC oxidoreductase 394 512 2.1E-19 T 13-09-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 THL1_RS14525 7e9c902473013234f99c225782b886fd 526 SUPERFAMILY SSF51905 13 309 7.47E-60 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS14525 7e9c902473013234f99c225782b886fd 526 SUPERFAMILY SSF51905 461 519 7.47E-60 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS14525 7e9c902473013234f99c225782b886fd 526 SUPERFAMILY SSF54373 367 462 4.71E-12 T 13-09-2016 THL1_RS14525 7e9c902473013234f99c225782b886fd 526 PANTHER PTHR11552:SF139 13 517 5.3E-98 T 13-09-2016 THL1_RS14525 7e9c902473013234f99c225782b886fd 526 Pfam PF00732 GMC oxidoreductase 14 282 6.5E-17 T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS15930 267a9bce43463d0327a3002f20fa4a3b 651 PANTHER PTHR24095 1 648 0.0 T 13-09-2016 THL1_RS15930 267a9bce43463d0327a3002f20fa4a3b 651 Gene3D G3DSA:3.40.50.980 275 409 1.2E-15 T 13-09-2016 THL1_RS15930 267a9bce43463d0327a3002f20fa4a3b 651 Pfam PF00501 AMP-binding enzyme 97 525 4.7E-44 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS15930 267a9bce43463d0327a3002f20fa4a3b 651 Pfam PF13193 AMP-binding enzyme C-terminal domain 543 613 1.6E-5 T 13-09-2016 IPR025110 AMP-binding enzyme C-terminal domain THL1_RS15930 267a9bce43463d0327a3002f20fa4a3b 651 ProSitePatterns PS00455 Putative AMP-binding domain signature. 269 280 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS15930 267a9bce43463d0327a3002f20fa4a3b 651 Gene3D G3DSA:3.40.50.980 91 274 2.5E-27 T 13-09-2016 THL1_RS15930 267a9bce43463d0327a3002f20fa4a3b 651 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 2 651 5.9E-280 T 13-09-2016 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16 THL1_RS15930 267a9bce43463d0327a3002f20fa4a3b 651 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 36 91 3.5E-12 T 13-09-2016 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 THL1_RS15930 267a9bce43463d0327a3002f20fa4a3b 651 SUPERFAMILY SSF56801 19 643 8.37E-128 T 13-09-2016 THL1_RS15930 267a9bce43463d0327a3002f20fa4a3b 651 Gene3D G3DSA:3.30.300.30 525 628 1.4E-15 T 13-09-2016 THL1_RS15930 267a9bce43463d0327a3002f20fa4a3b 651 PANTHER PTHR24095:SF46 1 648 0.0 T 13-09-2016 THL1_RS21185 e348f0ab782a8902ee944cfef6d49ecf 487 PANTHER PTHR11699:SF197 1 453 5.8E-292 T 13-09-2016 THL1_RS21185 e348f0ab782a8902ee944cfef6d49ecf 487 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 271 282 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS21185 e348f0ab782a8902ee944cfef6d49ecf 487 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 243 250 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS21185 e348f0ab782a8902ee944cfef6d49ecf 487 Gene3D G3DSA:3.40.309.10 258 444 3.5E-44 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS21185 e348f0ab782a8902ee944cfef6d49ecf 487 TIGRFAM TIGR03240 arg_catab_astD: succinylglutamate-semialdehyde dehydrogenase 4 486 6.3E-257 T 13-09-2016 IPR017649 Succinylglutamate-semialdehyde dehydrogenase GO:0006527|GO:0043824|GO:0055114 KEGG: 00330+1.2.1.71|UniPathway: UPA00185 THL1_RS21185 e348f0ab782a8902ee944cfef6d49ecf 487 Pfam PF00171 Aldehyde dehydrogenase family 10 461 2.4E-124 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS21185 e348f0ab782a8902ee944cfef6d49ecf 487 Hamap MF_01174 N-succinylglutamate 5-semialdehyde dehydrogenase [astD]. 2 487 59.025 T 13-09-2016 IPR017649 Succinylglutamate-semialdehyde dehydrogenase GO:0006527|GO:0043824|GO:0055114 KEGG: 00330+1.2.1.71|UniPathway: UPA00185 THL1_RS21185 e348f0ab782a8902ee944cfef6d49ecf 487 SUPERFAMILY SSF53720 3 456 4.45E-125 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS21185 e348f0ab782a8902ee944cfef6d49ecf 487 PANTHER PTHR11699 1 453 5.8E-292 T 13-09-2016 THL1_RS21185 e348f0ab782a8902ee944cfef6d49ecf 487 Gene3D G3DSA:3.40.605.10 4 257 3.4E-74 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS12925 eae441399b48aad2d467bede06093f2f 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 6.6E-9 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS12925 eae441399b48aad2d467bede06093f2f 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 24 39 6.6E-9 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS12925 eae441399b48aad2d467bede06093f2f 115 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 72 87 6.6E-9 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS12925 eae441399b48aad2d467bede06093f2f 115 Gene3D G3DSA:1.10.10.10 22 103 2.6E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12925 eae441399b48aad2d467bede06093f2f 115 Pfam PF01022 Bacterial regulatory protein, arsR family 30 75 4.2E-8 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS12925 eae441399b48aad2d467bede06093f2f 115 PANTHER PTHR33154 23 113 3.0E-17 T 13-09-2016 THL1_RS12925 eae441399b48aad2d467bede06093f2f 115 SUPERFAMILY SSF46785 21 102 1.22E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12925 eae441399b48aad2d467bede06093f2f 115 SMART SM00418 22 101 1.0E-13 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS07455 68a672c87d02316d5be5a597d5212791 440 Pfam PF01645 Conserved region in glutamate synthase 79 331 1.8E-80 T 13-09-2016 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 THL1_RS07455 68a672c87d02316d5be5a597d5212791 440 Pfam PF01645 Conserved region in glutamate synthase 360 402 4.6E-5 T 13-09-2016 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 THL1_RS07455 68a672c87d02316d5be5a597d5212791 440 PANTHER PTHR11938 350 393 3.2E-53 T 13-09-2016 THL1_RS07455 68a672c87d02316d5be5a597d5212791 440 Gene3D G3DSA:3.20.20.70 3 437 5.1E-124 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS07455 68a672c87d02316d5be5a597d5212791 440 PIRSF PIRSF500061 1 439 2.6E-172 T 13-09-2016 THL1_RS07455 68a672c87d02316d5be5a597d5212791 440 PANTHER PTHR11938 122 333 3.2E-53 T 13-09-2016 THL1_RS07455 68a672c87d02316d5be5a597d5212791 440 PANTHER PTHR11938:SF65 122 333 3.2E-53 T 13-09-2016 THL1_RS07455 68a672c87d02316d5be5a597d5212791 440 PANTHER PTHR11938:SF65 350 393 3.2E-53 T 13-09-2016 THL1_RS07455 68a672c87d02316d5be5a597d5212791 440 PIRSF PIRSF006429 1 438 1.4E-150 T 13-09-2016 IPR024188 Glutamate synthase large subunit-like protein THL1_RS07455 68a672c87d02316d5be5a597d5212791 440 SUPERFAMILY SSF51395 10 422 2.69E-95 T 13-09-2016 THL1_RS25735 6f4042955e3722858bdb448809958b30 148 Gene3D G3DSA:3.40.630.30 8 141 5.3E-22 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS25735 6f4042955e3722858bdb448809958b30 148 PANTHER PTHR23091:SF277 15 125 1.3E-21 T 13-09-2016 THL1_RS25735 6f4042955e3722858bdb448809958b30 148 Pfam PF13673 Acetyltransferase (GNAT) domain 61 130 6.0E-15 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS25735 6f4042955e3722858bdb448809958b30 148 SUPERFAMILY SSF55729 9 146 1.75E-21 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS25735 6f4042955e3722858bdb448809958b30 148 PANTHER PTHR23091 15 125 1.3E-21 T 13-09-2016 THL1_RS10545 57cebb2f34903bf6f59b1d9e3f099049 530 Pfam PF01266 FAD dependent oxidoreductase 22 348 3.2E-45 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS10545 57cebb2f34903bf6f59b1d9e3f099049 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 95 107 1.9E-23 T 13-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 THL1_RS10545 57cebb2f34903bf6f59b1d9e3f099049 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 363 375 1.9E-23 T 13-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 THL1_RS10545 57cebb2f34903bf6f59b1d9e3f099049 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 50 62 1.9E-23 T 13-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 THL1_RS10545 57cebb2f34903bf6f59b1d9e3f099049 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 332 338 1.9E-23 T 13-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 THL1_RS10545 57cebb2f34903bf6f59b1d9e3f099049 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 34 44 1.9E-23 T 13-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 THL1_RS10545 57cebb2f34903bf6f59b1d9e3f099049 530 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 21 33 1.9E-23 T 13-09-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 THL1_RS10545 57cebb2f34903bf6f59b1d9e3f099049 530 PANTHER PTHR11985:SF1 8 518 8.9E-153 T 13-09-2016 THL1_RS10545 57cebb2f34903bf6f59b1d9e3f099049 530 PANTHER PTHR11985 8 518 8.9E-153 T 13-09-2016 THL1_RS10545 57cebb2f34903bf6f59b1d9e3f099049 530 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 412 504 4.7E-11 T 13-09-2016 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 THL1_RS10545 57cebb2f34903bf6f59b1d9e3f099049 530 Gene3D G3DSA:3.50.50.60 19 289 7.2E-36 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10545 57cebb2f34903bf6f59b1d9e3f099049 530 SUPERFAMILY SSF51905 21 341 1.02E-33 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS09425 6cd757f2781ed268132a0ba19c992d9f 591 Gene3D G3DSA:3.40.50.1220 187 361 5.4E-50 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS09425 6cd757f2781ed268132a0ba19c992d9f 591 SUPERFAMILY SSF52518 369 571 2.86E-50 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS09425 6cd757f2781ed268132a0ba19c992d9f 591 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 172 2.1E-51 T 13-09-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 THL1_RS09425 6cd757f2781ed268132a0ba19c992d9f 591 TIGRFAM TIGR01504 glyox_carbo_lig: glyoxylate carboligase 2 590 0.0 T 13-09-2016 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47|UniPathway: UPA00864 THL1_RS09425 6cd757f2781ed268132a0ba19c992d9f 591 Gene3D G3DSA:3.40.50.970 4 180 3.1E-59 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS09425 6cd757f2781ed268132a0ba19c992d9f 591 SUPERFAMILY SSF52467 161 348 8.28E-47 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS09425 6cd757f2781ed268132a0ba19c992d9f 591 PANTHER PTHR18968 1 587 0.0 T 13-09-2016 THL1_RS09425 6cd757f2781ed268132a0ba19c992d9f 591 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 553 1.6E-31 T 13-09-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THL1_RS09425 6cd757f2781ed268132a0ba19c992d9f 591 PANTHER PTHR18968:SF14 1 587 0.0 T 13-09-2016 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47|UniPathway: UPA00864 THL1_RS09425 6cd757f2781ed268132a0ba19c992d9f 591 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 328 3.0E-35 T 13-09-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 THL1_RS09425 6cd757f2781ed268132a0ba19c992d9f 591 SUPERFAMILY SSF52518 3 181 2.82E-48 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS09425 6cd757f2781ed268132a0ba19c992d9f 591 Gene3D G3DSA:3.40.50.970 362 577 1.3E-57 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS24260 75bf83d49747f9b624e9c1290e5b728e 107 SUPERFAMILY SSF50022 3 103 3.01E-24 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS24260 75bf83d49747f9b624e9c1290e5b728e 107 Gene3D G3DSA:2.102.10.10 3 103 2.1E-24 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS24260 75bf83d49747f9b624e9c1290e5b728e 107 PANTHER PTHR40261:SF2 1 103 2.2E-36 T 13-09-2016 THL1_RS24260 75bf83d49747f9b624e9c1290e5b728e 107 Pfam PF00355 Rieske [2Fe-2S] domain 3 86 1.4E-13 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS24260 75bf83d49747f9b624e9c1290e5b728e 107 PANTHER PTHR40261 1 103 2.2E-36 T 13-09-2016 THL1_RS18280 65cd28d80fbc600f1e29fa2ed9e6fdce 198 PANTHER PTHR11080 1 194 8.9E-61 T 13-09-2016 THL1_RS18280 65cd28d80fbc600f1e29fa2ed9e6fdce 198 SUPERFAMILY SSF52499 4 196 1.44E-44 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS18280 65cd28d80fbc600f1e29fa2ed9e6fdce 198 Pfam PF00857 Isochorismatase family 24 189 1.0E-31 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS18280 65cd28d80fbc600f1e29fa2ed9e6fdce 198 Gene3D G3DSA:3.40.50.850 9 195 4.3E-44 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS18280 65cd28d80fbc600f1e29fa2ed9e6fdce 198 PANTHER PTHR11080:SF17 1 194 8.9E-61 T 13-09-2016 THL1_RS22625 bcc1183668da15f0de34a856661b139b 185 Pfam PF01765 Ribosome recycling factor 21 183 1.5E-61 T 13-09-2016 IPR023584 Ribosome recycling factor domain THL1_RS22625 bcc1183668da15f0de34a856661b139b 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.655 T 13-09-2016 IPR002661 Ribosome recycling factor GO:0006412 THL1_RS22625 bcc1183668da15f0de34a856661b139b 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 1.1E-69 T 13-09-2016 IPR002661 Ribosome recycling factor GO:0006412 THL1_RS22625 bcc1183668da15f0de34a856661b139b 185 SUPERFAMILY SSF55194 2 183 1.57E-70 T 13-09-2016 IPR023584 Ribosome recycling factor domain THL1_RS22625 bcc1183668da15f0de34a856661b139b 185 PANTHER PTHR20982 1 185 3.2E-78 T 13-09-2016 IPR002661 Ribosome recycling factor GO:0006412 THL1_RS22625 bcc1183668da15f0de34a856661b139b 185 Gene3D G3DSA:1.10.132.20 67 185 2.1E-43 T 13-09-2016 IPR023584 Ribosome recycling factor domain THL1_RS09265 fc449b33f2031691c00cc44deaeeb4d6 288 Gene3D G3DSA:1.10.10.10 1 79 5.9E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09265 fc449b33f2031691c00cc44deaeeb4d6 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.7E-19 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS09265 fc449b33f2031691c00cc44deaeeb4d6 288 SUPERFAMILY SSF46785 1 108 2.18E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09265 fc449b33f2031691c00cc44deaeeb4d6 288 Pfam PF03466 LysR substrate binding domain 85 281 1.3E-41 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS09265 fc449b33f2031691c00cc44deaeeb4d6 288 SUPERFAMILY SSF53850 85 281 1.92E-37 T 13-09-2016 THL1_RS09265 fc449b33f2031691c00cc44deaeeb4d6 288 PANTHER PTHR30126:SF31 1 281 1.1E-112 T 13-09-2016 THL1_RS09265 fc449b33f2031691c00cc44deaeeb4d6 288 PANTHER PTHR30126 1 281 1.1E-112 T 13-09-2016 THL1_RS09265 fc449b33f2031691c00cc44deaeeb4d6 288 Gene3D G3DSA:3.40.190.10 80 189 1.7E-25 T 13-09-2016 THL1_RS09265 fc449b33f2031691c00cc44deaeeb4d6 288 Gene3D G3DSA:3.40.190.10 190 255 1.0E-9 T 13-09-2016 THL1_RS24820 c668f029239a1e0e91bbad98c25d2b10 640 PANTHER PTHR13833:SF51 103 379 4.7E-41 T 13-09-2016 THL1_RS24820 c668f029239a1e0e91bbad98c25d2b10 640 Gene3D G3DSA:2.130.10.10 121 403 7.8E-48 T 13-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THL1_RS24820 c668f029239a1e0e91bbad98c25d2b10 640 PANTHER PTHR13833 103 379 4.7E-41 T 13-09-2016 THL1_RS24820 c668f029239a1e0e91bbad98c25d2b10 640 Pfam PF02239 Cytochrome D1 heme domain 223 327 1.6E-10 T 13-09-2016 THL1_RS24820 c668f029239a1e0e91bbad98c25d2b10 640 SUPERFAMILY SSF51004 150 407 1.7E-52 T 13-09-2016 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain THL1_RS27675 50284199df3f3fdacce1bc2ab75025bc 93 SMART SM00530 12 63 1.1E-5 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS27675 50284199df3f3fdacce1bc2ab75025bc 93 Pfam PF13560 Helix-turn-helix domain 8 61 2.2E-7 T 13-09-2016 THL1_RS27675 50284199df3f3fdacce1bc2ab75025bc 93 Gene3D G3DSA:1.10.260.40 3 61 2.4E-10 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS27675 50284199df3f3fdacce1bc2ab75025bc 93 SUPERFAMILY SSF47413 4 62 1.69E-10 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS08415 29a6b65db922c4a0c75baee8ac981f29 242 PANTHER PTHR11019 117 225 2.8E-28 T 13-09-2016 THL1_RS08415 29a6b65db922c4a0c75baee8ac981f29 242 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 171 213 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS08415 29a6b65db922c4a0c75baee8ac981f29 242 Pfam PF12833 Helix-turn-helix domain 146 218 1.2E-21 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS08415 29a6b65db922c4a0c75baee8ac981f29 242 Gene3D G3DSA:3.40.50.2300 22 103 8.4E-11 T 13-09-2016 THL1_RS08415 29a6b65db922c4a0c75baee8ac981f29 242 SUPERFAMILY SSF52172 23 97 3.27E-12 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS08415 29a6b65db922c4a0c75baee8ac981f29 242 Gene3D G3DSA:1.10.10.60 171 226 1.3E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS08415 29a6b65db922c4a0c75baee8ac981f29 242 SUPERFAMILY SSF46689 170 222 3.27E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS08415 29a6b65db922c4a0c75baee8ac981f29 242 PANTHER PTHR11019:SF11 117 225 2.8E-28 T 13-09-2016 THL1_RS08415 29a6b65db922c4a0c75baee8ac981f29 242 Pfam PF00072 Response regulator receiver domain 28 80 1.4E-5 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS08415 29a6b65db922c4a0c75baee8ac981f29 242 SUPERFAMILY SSF46689 121 167 6.63E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS08415 29a6b65db922c4a0c75baee8ac981f29 242 SMART SM00342 134 217 9.5E-28 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS08415 29a6b65db922c4a0c75baee8ac981f29 242 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 186 201 1.2E-6 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS08415 29a6b65db922c4a0c75baee8ac981f29 242 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 201 217 1.2E-6 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS08415 29a6b65db922c4a0c75baee8ac981f29 242 Gene3D G3DSA:1.10.10.60 120 170 7.1E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15370 da768a840cb942a1ad5f1ce286fbebe8 257 Pfam PF13416 Bacterial extracellular solute-binding protein 43 252 3.8E-19 T 13-09-2016 THL1_RS15370 da768a840cb942a1ad5f1ce286fbebe8 257 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 48 69 1.9E-47 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS15370 da768a840cb942a1ad5f1ce286fbebe8 257 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 75 89 1.9E-47 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS15370 da768a840cb942a1ad5f1ce286fbebe8 257 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 32 48 1.9E-47 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS15370 da768a840cb942a1ad5f1ce286fbebe8 257 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 155 169 1.9E-47 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS15370 da768a840cb942a1ad5f1ce286fbebe8 257 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 124 140 1.9E-47 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS15370 da768a840cb942a1ad5f1ce286fbebe8 257 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 178 197 1.9E-47 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS15370 da768a840cb942a1ad5f1ce286fbebe8 257 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 215 234 1.9E-47 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS15370 da768a840cb942a1ad5f1ce286fbebe8 257 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 91 104 1.9E-47 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS15370 da768a840cb942a1ad5f1ce286fbebe8 257 PANTHER PTHR30222 12 257 7.4E-124 T 13-09-2016 THL1_RS15370 da768a840cb942a1ad5f1ce286fbebe8 257 Gene3D G3DSA:3.40.190.10 134 257 9.7E-46 T 13-09-2016 THL1_RS15370 da768a840cb942a1ad5f1ce286fbebe8 257 PANTHER PTHR30222:SF11 12 257 7.4E-124 T 13-09-2016 THL1_RS15370 da768a840cb942a1ad5f1ce286fbebe8 257 Gene3D G3DSA:3.40.190.10 25 133 1.2E-36 T 13-09-2016 THL1_RS15370 da768a840cb942a1ad5f1ce286fbebe8 257 SUPERFAMILY SSF53850 26 256 1.09E-66 T 13-09-2016 THL1_RS03820 35367bd51ec52abc09f7b411830f6701 289 Gene3D G3DSA:1.25.40.10 121 201 2.8E-11 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS03820 35367bd51ec52abc09f7b411830f6701 289 TIGRFAM TIGR01068 thioredoxin: thioredoxin 14 110 8.7E-30 T 13-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THL1_RS03820 35367bd51ec52abc09f7b411830f6701 289 Pfam PF14559 Tetratricopeptide repeat 129 195 8.8E-12 T 13-09-2016 THL1_RS03820 35367bd51ec52abc09f7b411830f6701 289 PANTHER PTHR10438 10 114 2.4E-35 T 13-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THL1_RS03820 35367bd51ec52abc09f7b411830f6701 289 PANTHER PTHR10438 209 230 2.4E-35 T 13-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THL1_RS03820 35367bd51ec52abc09f7b411830f6701 289 Gene3D G3DSA:1.25.40.10 202 289 4.1E-26 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS03820 35367bd51ec52abc09f7b411830f6701 289 ProSitePatterns PS00194 Thioredoxin family active site. 29 47 - T 13-09-2016 IPR017937 Thioredoxin, conserved site GO:0045454 THL1_RS03820 35367bd51ec52abc09f7b411830f6701 289 Pfam PF14561 Tetratricopeptide repeat 200 289 2.0E-23 T 13-09-2016 THL1_RS03820 35367bd51ec52abc09f7b411830f6701 289 SUPERFAMILY SSF48452 123 251 3.36E-6 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS03820 35367bd51ec52abc09f7b411830f6701 289 PRINTS PR00421 Thioredoxin family signature 36 45 1.5E-7 T 13-09-2016 THL1_RS03820 35367bd51ec52abc09f7b411830f6701 289 PRINTS PR00421 Thioredoxin family signature 28 36 1.5E-7 T 13-09-2016 THL1_RS03820 35367bd51ec52abc09f7b411830f6701 289 PRINTS PR00421 Thioredoxin family signature 76 87 1.5E-7 T 13-09-2016 THL1_RS03820 35367bd51ec52abc09f7b411830f6701 289 SUPERFAMILY SSF52833 10 112 8.83E-35 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS03820 35367bd51ec52abc09f7b411830f6701 289 Gene3D G3DSA:3.40.30.10 8 111 2.7E-32 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS03820 35367bd51ec52abc09f7b411830f6701 289 Pfam PF00085 Thioredoxin 9 109 5.7E-27 T 13-09-2016 IPR013766 Thioredoxin domain GO:0045454 THL1_RS08670 1f7c972f6dea21ae0dc92062e38fd9de 95 PANTHER PTHR12962 12 94 1.7E-24 T 13-09-2016 THL1_RS08670 1f7c972f6dea21ae0dc92062e38fd9de 95 PANTHER PTHR12962:SF1 12 94 1.7E-24 T 13-09-2016 THL1_RS08670 1f7c972f6dea21ae0dc92062e38fd9de 95 PIRSF PIRSF002599 2 95 4.9E-19 T 13-09-2016 IPR012156 Cold shock, CspA GO:0003676 THL1_RS08670 1f7c972f6dea21ae0dc92062e38fd9de 95 Pfam PF06961 Protein of unknown function (DUF1294) 20 73 4.1E-22 T 13-09-2016 IPR010718 Protein of unknown function DUF1294 THL1_RS14600 3f42033c11157b15f8518a0de93b1703 316 PANTHER PTHR30537:SF26 9 316 3.3E-61 T 13-09-2016 THL1_RS14600 3f42033c11157b15f8518a0de93b1703 316 PANTHER PTHR30537 9 316 3.3E-61 T 13-09-2016 THL1_RS14600 3f42033c11157b15f8518a0de93b1703 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 53 64 1.5E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14600 3f42033c11157b15f8518a0de93b1703 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 53 1.5E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14600 3f42033c11157b15f8518a0de93b1703 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 43 1.5E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14600 3f42033c11157b15f8518a0de93b1703 316 SUPERFAMILY SSF53850 103 315 3.26E-23 T 13-09-2016 THL1_RS14600 3f42033c11157b15f8518a0de93b1703 316 Gene3D G3DSA:3.40.190.10 191 284 1.4E-10 T 13-09-2016 THL1_RS14600 3f42033c11157b15f8518a0de93b1703 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 75 4.2E-20 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14600 3f42033c11157b15f8518a0de93b1703 316 Pfam PF03466 LysR substrate binding domain 103 314 3.2E-20 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS14600 3f42033c11157b15f8518a0de93b1703 316 Gene3D G3DSA:3.40.190.10 105 190 4.7E-17 T 13-09-2016 THL1_RS14600 3f42033c11157b15f8518a0de93b1703 316 Gene3D G3DSA:1.10.10.10 16 99 2.6E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14600 3f42033c11157b15f8518a0de93b1703 316 SUPERFAMILY SSF46785 12 96 6.68E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS22160 5e0e85b28a53b44d579d3b8fbe93954c 200 PRINTS PR00050 Cold shock protein signature 153 162 4.3E-15 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS22160 5e0e85b28a53b44d579d3b8fbe93954c 200 PRINTS PR00050 Cold shock protein signature 133 148 4.3E-15 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS22160 5e0e85b28a53b44d579d3b8fbe93954c 200 PRINTS PR00050 Cold shock protein signature 168 186 4.3E-15 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS22160 5e0e85b28a53b44d579d3b8fbe93954c 200 ProSitePatterns PS00352 'Cold-shock' domain signature. 144 162 - T 13-09-2016 IPR019844 Cold-shock conserved site THL1_RS22160 5e0e85b28a53b44d579d3b8fbe93954c 200 PANTHER PTHR11544 109 195 8.8E-37 T 13-09-2016 THL1_RS22160 5e0e85b28a53b44d579d3b8fbe93954c 200 SMART SM00357 132 195 1.5E-25 T 13-09-2016 IPR011129 Cold shock protein GO:0003676 THL1_RS22160 5e0e85b28a53b44d579d3b8fbe93954c 200 Pfam PF00313 'Cold-shock' DNA-binding domain 132 193 8.3E-26 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS22160 5e0e85b28a53b44d579d3b8fbe93954c 200 Gene3D G3DSA:2.40.50.140 131 193 2.0E-27 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS22160 5e0e85b28a53b44d579d3b8fbe93954c 200 SUPERFAMILY SSF50249 127 193 1.54E-22 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS19805 3f55e40ca9c287343e79260e4ed18893 237 Gene3D G3DSA:3.40.50.2300 2 126 3.6E-39 T 13-09-2016 THL1_RS19805 3f55e40ca9c287343e79260e4ed18893 237 SUPERFAMILY SSF52172 2 128 3.13E-39 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS19805 3f55e40ca9c287343e79260e4ed18893 237 Pfam PF00072 Response regulator receiver domain 5 113 1.8E-29 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS19805 3f55e40ca9c287343e79260e4ed18893 237 PANTHER PTHR26402:SF596 3 233 6.0E-98 T 13-09-2016 THL1_RS19805 3f55e40ca9c287343e79260e4ed18893 237 SMART SM00862 153 230 1.9E-22 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS19805 3f55e40ca9c287343e79260e4ed18893 237 Gene3D G3DSA:1.10.10.10 132 233 1.9E-27 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19805 3f55e40ca9c287343e79260e4ed18893 237 SMART SM00448 3 113 2.0E-41 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS19805 3f55e40ca9c287343e79260e4ed18893 237 SUPERFAMILY SSF46894 136 232 3.4E-25 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS19805 3f55e40ca9c287343e79260e4ed18893 237 PANTHER PTHR26402 3 233 6.0E-98 T 13-09-2016 THL1_RS19805 3f55e40ca9c287343e79260e4ed18893 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 230 2.5E-22 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS03500 78ff17304680afcf35987cd2e5a884de 123 PANTHER PTHR11652 1 116 2.5E-76 T 13-09-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03500 78ff17304680afcf35987cd2e5a884de 123 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 9.8E-70 T 13-09-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 THL1_RS03500 78ff17304680afcf35987cd2e5a884de 123 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.804 T 13-09-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 THL1_RS03500 78ff17304680afcf35987cd2e5a884de 123 PRINTS PR01034 Ribosomal protein S12 signature 42 57 9.3E-61 T 13-09-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 THL1_RS03500 78ff17304680afcf35987cd2e5a884de 123 PRINTS PR01034 Ribosomal protein S12 signature 27 42 9.3E-61 T 13-09-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 THL1_RS03500 78ff17304680afcf35987cd2e5a884de 123 PRINTS PR01034 Ribosomal protein S12 signature 94 110 9.3E-61 T 13-09-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 THL1_RS03500 78ff17304680afcf35987cd2e5a884de 123 PRINTS PR01034 Ribosomal protein S12 signature 58 77 9.3E-61 T 13-09-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 THL1_RS03500 78ff17304680afcf35987cd2e5a884de 123 PRINTS PR01034 Ribosomal protein S12 signature 110 122 9.3E-61 T 13-09-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 THL1_RS03500 78ff17304680afcf35987cd2e5a884de 123 PRINTS PR01034 Ribosomal protein S12 signature 77 94 9.3E-61 T 13-09-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 THL1_RS03500 78ff17304680afcf35987cd2e5a884de 123 Pfam PF00164 Ribosomal protein S12/S23 5 123 6.2E-43 T 13-09-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03500 78ff17304680afcf35987cd2e5a884de 123 PIRSF PIRSF002133 1 123 2.9E-53 T 13-09-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03500 78ff17304680afcf35987cd2e5a884de 123 SUPERFAMILY SSF50249 3 123 8.57E-52 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS03500 78ff17304680afcf35987cd2e5a884de 123 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 13-09-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03500 78ff17304680afcf35987cd2e5a884de 123 Gene3D G3DSA:2.40.50.140 1 123 3.9E-65 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS16175 277b1fb2dc5a2a360d52d7ca9aefad93 273 Gene3D G3DSA:2.160.20.10 31 188 2.0E-11 T 13-09-2016 IPR012334 Pectin lyase fold THL1_RS16175 277b1fb2dc5a2a360d52d7ca9aefad93 273 SUPERFAMILY SSF51126 28 187 2.59E-9 T 13-09-2016 IPR011050 Pectin lyase fold/virulence factor THL1_RS12055 798497ce166350a817c7abdded35d847 747 SUPERFAMILY SSF54665 221 304 2.22E-14 T 13-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead THL1_RS12055 798497ce166350a817c7abdded35d847 747 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 614 695 2.1E-14 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS12055 798497ce166350a817c7abdded35d847 747 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 327 568 1.0E-34 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS12055 798497ce166350a817c7abdded35d847 747 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 28 198 5.9E-18 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS12055 798497ce166350a817c7abdded35d847 747 Gene3D G3DSA:3.30.365.10 568 746 6.8E-42 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS12055 798497ce166350a817c7abdded35d847 747 Gene3D G3DSA:3.90.1170.50 189 302 2.3E-22 T 13-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead THL1_RS12055 798497ce166350a817c7abdded35d847 747 SMART SM01008 220 304 5.9E-24 T 13-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead THL1_RS12055 798497ce166350a817c7abdded35d847 747 PIRSF PIRSF036389 8 747 3.8E-252 T 13-09-2016 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related THL1_RS12055 798497ce166350a817c7abdded35d847 747 PANTHER PTHR11908 127 736 2.9E-246 T 13-09-2016 THL1_RS12055 798497ce166350a817c7abdded35d847 747 Gene3D G3DSA:3.30.365.10 54 186 1.7E-37 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS12055 798497ce166350a817c7abdded35d847 747 SUPERFAMILY SSF56003 326 740 3.14E-117 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS12055 798497ce166350a817c7abdded35d847 747 SUPERFAMILY SSF56003 19 246 4.53E-43 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS12055 798497ce166350a817c7abdded35d847 747 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 16 38 4.3E-5 T 13-09-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THL1_RS12055 798497ce166350a817c7abdded35d847 747 Gene3D G3DSA:3.30.365.10 402 567 9.0E-35 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS12055 798497ce166350a817c7abdded35d847 747 PANTHER PTHR11908:SF79 127 736 2.9E-246 T 13-09-2016 THL1_RS12450 2de6aeaa49477c50d60811efd17ce672 100 PANTHER PTHR37526 3 99 2.7E-22 T 13-09-2016 THL1_RS12450 2de6aeaa49477c50d60811efd17ce672 100 Pfam PF04077 DsrH like protein 9 96 9.8E-23 T 13-09-2016 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 THL1_RS12450 2de6aeaa49477c50d60811efd17ce672 100 Gene3D G3DSA:3.40.1260.10 3 96 7.4E-19 T 13-09-2016 IPR027396 DsrEFH-like THL1_RS12450 2de6aeaa49477c50d60811efd17ce672 100 SUPERFAMILY SSF75169 3 99 4.04E-24 T 13-09-2016 IPR027396 DsrEFH-like THL1_RS12450 2de6aeaa49477c50d60811efd17ce672 100 TIGRFAM TIGR03011 sulf_tusB_dsrH: sulfur relay protein TusB/DsrH 4 99 4.3E-28 T 13-09-2016 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 THL1_RS12030 4c1535cf47e2a5a480e080215da39a07 413 PANTHER PTHR30158 1 397 1.8E-190 T 13-09-2016 THL1_RS12030 4c1535cf47e2a5a480e080215da39a07 413 SUPERFAMILY SSF111369 53 294 1.44E-70 T 13-09-2016 THL1_RS12030 4c1535cf47e2a5a480e080215da39a07 413 PANTHER PTHR30158:SF2 1 397 1.8E-190 T 13-09-2016 THL1_RS12030 4c1535cf47e2a5a480e080215da39a07 413 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 64 290 7.4E-19 T 13-09-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THL1_RS12030 4c1535cf47e2a5a480e080215da39a07 413 Gene3D G3DSA:2.40.50.100 172 205 2.0E-25 T 13-09-2016 THL1_RS12030 4c1535cf47e2a5a480e080215da39a07 413 Gene3D G3DSA:2.40.50.100 63 97 2.0E-25 T 13-09-2016 THL1_RS12030 4c1535cf47e2a5a480e080215da39a07 413 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 39 371 1.2E-78 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS13825 ef17794b2fded0390f160295e6f84e66 312 SUPERFAMILY SSF46785 181 309 1.48E-15 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13825 ef17794b2fded0390f160295e6f84e66 312 SUPERFAMILY SSF50475 8 159 7.36E-51 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS13825 ef17794b2fded0390f160295e6f84e66 312 Gene3D G3DSA:1.10.10.10 169 309 2.6E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13825 ef17794b2fded0390f160295e6f84e66 312 PANTHER PTHR30466 3 158 7.6E-41 T 13-09-2016 THL1_RS13825 ef17794b2fded0390f160295e6f84e66 312 PANTHER PTHR30466:SF1 3 158 7.6E-41 T 13-09-2016 THL1_RS13825 ef17794b2fded0390f160295e6f84e66 312 Pfam PF01613 Flavin reductase like domain 18 159 9.7E-37 T 13-09-2016 IPR002563 Flavin reductase like domain GO:0010181 THL1_RS13825 ef17794b2fded0390f160295e6f84e66 312 Gene3D G3DSA:2.30.110.10 5 158 5.4E-59 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS13825 ef17794b2fded0390f160295e6f84e66 312 SMART SM00903 17 160 1.9E-64 T 13-09-2016 IPR002563 Flavin reductase like domain GO:0010181 THL1_RS21210 293ba600a78e105e988c7bcf51042bfa 254 SUPERFAMILY SSF52540 4 248 2.84E-73 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21210 293ba600a78e105e988c7bcf51042bfa 254 PIRSF PIRSF039085 1 254 3.3E-117 T 13-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 THL1_RS21210 293ba600a78e105e988c7bcf51042bfa 254 Pfam PF00005 ABC transporter 19 178 6.5E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS21210 293ba600a78e105e988c7bcf51042bfa 254 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS21210 293ba600a78e105e988c7bcf51042bfa 254 Gene3D G3DSA:3.40.50.300 4 249 4.4E-78 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21210 293ba600a78e105e988c7bcf51042bfa 254 PANTHER PTHR24220:SF347 5 254 8.8E-176 T 13-09-2016 THL1_RS21210 293ba600a78e105e988c7bcf51042bfa 254 SMART SM00382 28 225 2.2E-14 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS21210 293ba600a78e105e988c7bcf51042bfa 254 PANTHER PTHR24220 5 254 8.8E-176 T 13-09-2016 THL1_RS25465 7179d583c9da3eb6860f8e13c25a93f2 154 Gene3D G3DSA:2.40.50.100 78 153 6.0E-31 T 13-09-2016 THL1_RS25465 7179d583c9da3eb6860f8e13c25a93f2 154 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 153 9.0E-59 T 13-09-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 THL1_RS25465 7179d583c9da3eb6860f8e13c25a93f2 154 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 110 127 - T 13-09-2016 IPR001882 Biotin-binding site THL1_RS25465 7179d583c9da3eb6860f8e13c25a93f2 154 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 115 128 1.2E-17 T 13-09-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 THL1_RS25465 7179d583c9da3eb6860f8e13c25a93f2 154 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 100 114 1.2E-17 T 13-09-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 THL1_RS25465 7179d583c9da3eb6860f8e13c25a93f2 154 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 83 96 1.2E-17 T 13-09-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 THL1_RS25465 7179d583c9da3eb6860f8e13c25a93f2 154 Pfam PF00364 Biotin-requiring enzyme 80 153 9.3E-26 T 13-09-2016 IPR000089 Biotin/lipoyl attachment THL1_RS25465 7179d583c9da3eb6860f8e13c25a93f2 154 PANTHER PTHR23151 1 154 6.5E-50 T 13-09-2016 THL1_RS25465 7179d583c9da3eb6860f8e13c25a93f2 154 SUPERFAMILY SSF51230 79 153 6.94E-25 T 13-09-2016 IPR011053 Single hybrid motif THL1_RS13205 24f3ad8320e12695b211dbf17a332b7a 318 SUPERFAMILY SSF56529 60 316 4.84E-58 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS13205 24f3ad8320e12695b211dbf17a332b7a 318 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 72 315 8.2E-52 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS13205 24f3ad8320e12695b211dbf17a332b7a 318 PANTHER PTHR11820:SF6 287 318 1.9E-67 T 13-09-2016 THL1_RS13205 24f3ad8320e12695b211dbf17a332b7a 318 PANTHER PTHR11820 287 318 1.9E-67 T 13-09-2016 THL1_RS13205 24f3ad8320e12695b211dbf17a332b7a 318 PANTHER PTHR11820 1 260 1.9E-67 T 13-09-2016 THL1_RS13205 24f3ad8320e12695b211dbf17a332b7a 318 PANTHER PTHR11820:SF6 1 260 1.9E-67 T 13-09-2016 THL1_RS13205 24f3ad8320e12695b211dbf17a332b7a 318 Gene3D G3DSA:3.90.850.10 287 317 4.1E-63 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS13205 24f3ad8320e12695b211dbf17a332b7a 318 Gene3D G3DSA:3.90.850.10 62 253 4.1E-63 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS13205 24f3ad8320e12695b211dbf17a332b7a 318 Pfam PF10370 Domain of unknown function (DUF2437) 5 65 4.9E-5 T 13-09-2016 IPR018833 Domain of unknown function DUF2437 THL1_RS22295 e9399112d3b1d59cb3fdad6223b67c5c 450 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 28 450 65.896 T 13-09-2016 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 THL1_RS22295 e9399112d3b1d59cb3fdad6223b67c5c 450 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 275 446 9.1E-27 T 13-09-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 THL1_RS22295 e9399112d3b1d59cb3fdad6223b67c5c 450 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 272 442 3.3E-63 T 13-09-2016 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 THL1_RS22295 e9399112d3b1d59cb3fdad6223b67c5c 450 PANTHER PTHR11061 17 448 2.5E-124 T 13-09-2016 THL1_RS22295 e9399112d3b1d59cb3fdad6223b67c5c 450 SUPERFAMILY SSF53335 86 448 2.31E-82 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS22295 e9399112d3b1d59cb3fdad6223b67c5c 450 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 432 442 - T 13-09-2016 IPR030391 RNA methyltransferase TrmA, conserved site THL1_RS22295 e9399112d3b1d59cb3fdad6223b67c5c 450 PANTHER PTHR11061:SF30 17 448 2.5E-124 T 13-09-2016 THL1_RS22295 e9399112d3b1d59cb3fdad6223b67c5c 450 Gene3D G3DSA:2.40.50.140 19 97 7.1E-26 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS22295 e9399112d3b1d59cb3fdad6223b67c5c 450 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 381 411 - T 13-09-2016 IPR030390 RNA methyltransferase TrmA, active site THL1_RS22295 e9399112d3b1d59cb3fdad6223b67c5c 450 SUPERFAMILY SSF50249 14 75 1.66E-13 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS22295 e9399112d3b1d59cb3fdad6223b67c5c 450 Gene3D G3DSA:3.40.50.150 270 448 2.9E-63 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS17050 2e60bb0c54c702cae6d63a8246044b12 410 PANTHER PTHR13693:SF57 2 403 1.1E-198 T 13-09-2016 THL1_RS17050 2e60bb0c54c702cae6d63a8246044b12 410 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 242 251 - T 13-09-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 THL1_RS17050 2e60bb0c54c702cae6d63a8246044b12 410 SUPERFAMILY SSF53383 2 395 2.69E-104 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS17050 2e60bb0c54c702cae6d63a8246044b12 410 PANTHER PTHR13693 2 403 1.1E-198 T 13-09-2016 THL1_RS17050 2e60bb0c54c702cae6d63a8246044b12 410 Pfam PF00155 Aminotransferase class I and II 44 388 5.2E-70 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS17050 2e60bb0c54c702cae6d63a8246044b12 410 Gene3D G3DSA:3.90.1150.10 279 391 6.1E-20 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS17050 2e60bb0c54c702cae6d63a8246044b12 410 Gene3D G3DSA:3.40.640.10 62 278 3.2E-86 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS17050 2e60bb0c54c702cae6d63a8246044b12 410 TIGRFAM TIGR01821 5aminolev_synth: 5-aminolevulinic acid synthase 2 400 2.2E-164 T 13-09-2016 IPR010961 Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase GO:0003870|GO:0030170|GO:0033014 KEGG: 00260+2.3.1.37|KEGG: 00860+2.3.1.37|MetaCyc: PWY-5189|MetaCyc: PWY-7536|Reactome: REACT_9431|UniPathway: UPA00251 THL1_RS06345 7bbc98f8d1f83c59d59298bb41be72b9 149 Gene3D G3DSA:3.90.1170.40 2 148 2.0E-53 T 13-09-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 THL1_RS06345 7bbc98f8d1f83c59d59298bb41be72b9 149 Pfam PF02391 MoaE protein 18 119 4.1E-35 T 13-09-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 THL1_RS06345 7bbc98f8d1f83c59d59298bb41be72b9 149 PANTHER PTHR23404 25 149 3.0E-38 T 13-09-2016 THL1_RS06345 7bbc98f8d1f83c59d59298bb41be72b9 149 PANTHER PTHR23404:SF2 25 149 3.0E-38 T 13-09-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 THL1_RS06345 7bbc98f8d1f83c59d59298bb41be72b9 149 SUPERFAMILY SSF54690 3 148 5.49E-51 T 13-09-2016 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|UniPathway: UPA00344 THL1_RS11400 b99152bebdd5a215b8f7d8775ccdde6e 383 Gene3D G3DSA:1.20.140.10 222 380 5.9E-70 T 13-09-2016 THL1_RS11400 b99152bebdd5a215b8f7d8775ccdde6e 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 7.2E-51 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS11400 b99152bebdd5a215b8f7d8775ccdde6e 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS11400 b99152bebdd5a215b8f7d8775ccdde6e 383 Gene3D G3DSA:1.10.540.10 3 120 7.7E-41 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS11400 b99152bebdd5a215b8f7d8775ccdde6e 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 1.6E-37 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS11400 b99152bebdd5a215b8f7d8775ccdde6e 383 PANTHER PTHR10909 3 378 4.1E-165 T 13-09-2016 THL1_RS11400 b99152bebdd5a215b8f7d8775ccdde6e 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 4.4E-27 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS11400 b99152bebdd5a215b8f7d8775ccdde6e 383 SUPERFAMILY SSF56645 2 243 6.15E-82 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS11400 b99152bebdd5a215b8f7d8775ccdde6e 383 SUPERFAMILY SSF47203 229 381 1.61E-58 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS11400 b99152bebdd5a215b8f7d8775ccdde6e 383 PANTHER PTHR10909:SF10 3 378 4.1E-165 T 13-09-2016 THL1_RS11400 b99152bebdd5a215b8f7d8775ccdde6e 383 PIRSF PIRSF016578 2 380 5.0E-26 T 13-09-2016 THL1_RS11400 b99152bebdd5a215b8f7d8775ccdde6e 383 Gene3D G3DSA:2.40.110.10 122 221 5.9E-39 T 13-09-2016 THL1_RS17785 13dacb0bf51c79a267b859ac0fb30ee6 192 PANTHER PTHR30328 3 188 4.1E-35 T 13-09-2016 THL1_RS17785 13dacb0bf51c79a267b859ac0fb30ee6 192 PANTHER PTHR30328:SF11 3 188 4.1E-35 T 13-09-2016 THL1_RS17785 13dacb0bf51c79a267b859ac0fb30ee6 192 SUPERFAMILY SSF46689 4 79 2.41E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17785 13dacb0bf51c79a267b859ac0fb30ee6 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 6.0E-16 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS17785 13dacb0bf51c79a267b859ac0fb30ee6 192 SUPERFAMILY SSF48498 77 191 5.78E-32 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS17785 13dacb0bf51c79a267b859ac0fb30ee6 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 5.8E-9 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS17785 13dacb0bf51c79a267b859ac0fb30ee6 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 5.8E-9 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS17785 13dacb0bf51c79a267b859ac0fb30ee6 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 53 - T 13-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site THL1_RS17785 13dacb0bf51c79a267b859ac0fb30ee6 192 Gene3D G3DSA:1.10.357.10 4 191 4.7E-36 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS12415 faf465e16f6cfabbdcb128283c6ac5ae 441 Gene3D G3DSA:3.40.50.300 10 151 2.3E-29 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS12415 faf465e16f6cfabbdcb128283c6ac5ae 441 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 50 157 2.9E-15 T 13-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 THL1_RS12415 faf465e16f6cfabbdcb128283c6ac5ae 441 SUPERFAMILY SSF52540 8 231 2.59E-45 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS12415 faf465e16f6cfabbdcb128283c6ac5ae 441 Gene3D G3DSA:1.10.8.60 152 235 2.3E-9 T 13-09-2016 THL1_RS12415 faf465e16f6cfabbdcb128283c6ac5ae 441 Gene3D G3DSA:1.20.272.10 242 340 1.2E-44 T 13-09-2016 THL1_RS12415 faf465e16f6cfabbdcb128283c6ac5ae 441 SUPERFAMILY SSF48019 245 427 2.38E-76 T 13-09-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 THL1_RS12415 faf465e16f6cfabbdcb128283c6ac5ae 441 Gene3D G3DSA:1.10.3710.10 341 438 8.5E-35 T 13-09-2016 THL1_RS12415 faf465e16f6cfabbdcb128283c6ac5ae 441 Pfam PF12002 MgsA AAA+ ATPase C terminal 261 427 1.6E-69 T 13-09-2016 IPR021886 MgsA AAA+ ATPase C-terminal THL1_RS12415 faf465e16f6cfabbdcb128283c6ac5ae 441 PANTHER PTHR13779:SF7 4 440 9.5E-195 T 13-09-2016 THL1_RS12415 faf465e16f6cfabbdcb128283c6ac5ae 441 Pfam PF16193 AAA C-terminal domain 184 260 2.3E-20 T 13-09-2016 IPR032423 AAA ATPase, C-terminal domain THL1_RS12415 faf465e16f6cfabbdcb128283c6ac5ae 441 PANTHER PTHR13779 4 440 9.5E-195 T 13-09-2016 THL1_RS12415 faf465e16f6cfabbdcb128283c6ac5ae 441 SMART SM00382 46 163 9.4E-14 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS12300 2b93042a7ee4e5af3f9a8cc18003b11d 137 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 7 124 20.368 T 13-09-2016 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 THL1_RS12300 2b93042a7ee4e5af3f9a8cc18003b11d 137 PANTHER PTHR11058 1 127 1.9E-66 T 13-09-2016 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 THL1_RS12300 2b93042a7ee4e5af3f9a8cc18003b11d 137 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 26 123 2.9E-34 T 13-09-2016 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 THL1_RS12300 2b93042a7ee4e5af3f9a8cc18003b11d 137 PANTHER PTHR11058:SF5 1 127 1.9E-66 T 13-09-2016 THL1_RS06735 68677c2e50dd8829b8f0c221bc51a6cd 265 PANTHER PTHR30193 1 264 8.9E-61 T 13-09-2016 THL1_RS06735 68677c2e50dd8829b8f0c221bc51a6cd 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 259 1.0E-13 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS06735 68677c2e50dd8829b8f0c221bc51a6cd 265 Gene3D G3DSA:1.10.3720.10 7 258 2.6E-39 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS06735 68677c2e50dd8829b8f0c221bc51a6cd 265 PANTHER PTHR30193:SF20 1 264 8.9E-61 T 13-09-2016 THL1_RS06735 68677c2e50dd8829b8f0c221bc51a6cd 265 SUPERFAMILY SSF161098 11 261 9.35E-42 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS21730 f781ede74e0e259feef9519a8a6a81ce 447 Gene3D G3DSA:1.20.1600.10 19 431 6.6E-69 T 13-09-2016 THL1_RS21730 f781ede74e0e259feef9519a8a6a81ce 447 Pfam PF02321 Outer membrane efflux protein 239 425 1.4E-30 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS21730 f781ede74e0e259feef9519a8a6a81ce 447 Pfam PF02321 Outer membrane efflux protein 23 216 2.1E-27 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS21730 f781ede74e0e259feef9519a8a6a81ce 447 SUPERFAMILY SSF56954 21 442 9.81E-82 T 13-09-2016 THL1_RS21730 f781ede74e0e259feef9519a8a6a81ce 447 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 20 439 1.0E-88 T 13-09-2016 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 THL1_RS21730 f781ede74e0e259feef9519a8a6a81ce 447 PANTHER PTHR30026 18 447 5.8E-77 T 13-09-2016 THL1_RS21730 f781ede74e0e259feef9519a8a6a81ce 447 PANTHER PTHR30026:SF3 18 447 5.8E-77 T 13-09-2016 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 THL1_RS19565 94ce884d83c535008920432ba91e721d 173 PANTHER PTHR35091:SF1 4 173 4.0E-67 T 13-09-2016 THL1_RS19565 94ce884d83c535008920432ba91e721d 173 Pfam PF03748 Flagellar basal body-associated protein FliL 74 173 3.3E-24 T 13-09-2016 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 THL1_RS19565 94ce884d83c535008920432ba91e721d 173 PANTHER PTHR35091 4 173 4.0E-67 T 13-09-2016 THL1_RS12630 e2f2a90ff14a4b15268ed9f87095b851 424 Pfam PF03573 outer membrane porin, OprD family 34 422 1.4E-153 T 13-09-2016 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 THL1_RS12630 e2f2a90ff14a4b15268ed9f87095b851 424 PANTHER PTHR34596 5 424 1.2E-159 T 13-09-2016 THL1_RS12630 e2f2a90ff14a4b15268ed9f87095b851 424 Gene3D G3DSA:2.40.160.10 39 424 1.2E-149 T 13-09-2016 IPR023614 Porin domain THL1_RS10995 906df899b5392b6a400b14d87426d71e 340 SUPERFAMILY SSF48179 179 331 2.13E-50 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS10995 906df899b5392b6a400b14d87426d71e 340 Gene3D G3DSA:1.10.1040.10 184 325 5.1E-52 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS10995 906df899b5392b6a400b14d87426d71e 340 Gene3D G3DSA:3.40.50.720 2 183 6.6E-60 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10995 906df899b5392b6a400b14d87426d71e 340 PIRSF PIRSF000114 1 332 1.2E-107 T 13-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 THL1_RS10995 906df899b5392b6a400b14d87426d71e 340 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 188 209 - T 13-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 THL1_RS10995 906df899b5392b6a400b14d87426d71e 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 198 222 2.7E-38 T 13-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 THL1_RS10995 906df899b5392b6a400b14d87426d71e 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 238 255 2.7E-38 T 13-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 THL1_RS10995 906df899b5392b6a400b14d87426d71e 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 173 197 2.7E-38 T 13-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 THL1_RS10995 906df899b5392b6a400b14d87426d71e 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 9 26 2.7E-38 T 13-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 THL1_RS10995 906df899b5392b6a400b14d87426d71e 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 133 153 2.7E-38 T 13-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 THL1_RS10995 906df899b5392b6a400b14d87426d71e 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 59 86 2.7E-38 T 13-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 THL1_RS10995 906df899b5392b6a400b14d87426d71e 340 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 180 320 8.6E-48 T 13-09-2016 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 THL1_RS10995 906df899b5392b6a400b14d87426d71e 340 SUPERFAMILY SSF51735 7 178 2.68E-50 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10995 906df899b5392b6a400b14d87426d71e 340 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 5 322 35.366 T 13-09-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 THL1_RS10995 906df899b5392b6a400b14d87426d71e 340 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 7 160 3.1E-49 T 13-09-2016 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 THL1_RS10995 906df899b5392b6a400b14d87426d71e 340 PANTHER PTHR11728 7 324 2.1E-123 T 13-09-2016 THL1_RS08475 241e1ce62f0ea65bb3a3ea9143f2c5d6 293 Pfam PF03466 LysR substrate binding domain 90 289 3.8E-30 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS08475 241e1ce62f0ea65bb3a3ea9143f2c5d6 293 PANTHER PTHR30537 1 290 2.8E-82 T 13-09-2016 THL1_RS08475 241e1ce62f0ea65bb3a3ea9143f2c5d6 293 PANTHER PTHR30537:SF26 1 290 2.8E-82 T 13-09-2016 THL1_RS08475 241e1ce62f0ea65bb3a3ea9143f2c5d6 293 SUPERFAMILY SSF46785 3 86 2.42E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08475 241e1ce62f0ea65bb3a3ea9143f2c5d6 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 6.8E-20 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08475 241e1ce62f0ea65bb3a3ea9143f2c5d6 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 6.1E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08475 241e1ce62f0ea65bb3a3ea9143f2c5d6 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 6.1E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08475 241e1ce62f0ea65bb3a3ea9143f2c5d6 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 6.1E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08475 241e1ce62f0ea65bb3a3ea9143f2c5d6 293 SUPERFAMILY SSF53850 98 291 3.44E-31 T 13-09-2016 THL1_RS08475 241e1ce62f0ea65bb3a3ea9143f2c5d6 293 Gene3D G3DSA:1.10.10.10 7 89 5.7E-26 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08475 241e1ce62f0ea65bb3a3ea9143f2c5d6 293 Gene3D G3DSA:3.40.190.10 97 190 5.4E-23 T 13-09-2016 THL1_RS18745 5a957e0a18828b328bb2d9195eccf943 349 Pfam PF01728 FtsJ-like methyltransferase 181 272 4.8E-9 T 13-09-2016 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 THL1_RS18745 5a957e0a18828b328bb2d9195eccf943 349 Gene3D G3DSA:3.40.50.150 179 273 9.0E-16 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS18745 5a957e0a18828b328bb2d9195eccf943 349 PANTHER PTHR37524:SF2 1 349 2.4E-168 T 13-09-2016 THL1_RS18745 5a957e0a18828b328bb2d9195eccf943 349 Hamap MF_01551 Ribosomal RNA large subunit methyltransferase M [rlmM]. 1 349 77.641 T 13-09-2016 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 THL1_RS18745 5a957e0a18828b328bb2d9195eccf943 349 PANTHER PTHR37524 1 349 2.4E-168 T 13-09-2016 THL1_RS18745 5a957e0a18828b328bb2d9195eccf943 349 SUPERFAMILY SSF53335 180 275 2.37E-15 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS18745 5a957e0a18828b328bb2d9195eccf943 349 PIRSF PIRSF028774 1 349 2.7E-161 T 13-09-2016 IPR011224 Ribosomal RNA large subunit methyltransferase M GO:0008168 THL1_RS18080 92a4666c952f901c0478071289551843 192 Pfam PF03861 ANTAR domain 134 184 2.2E-16 T 13-09-2016 IPR005561 ANTAR domain GO:0003723 THL1_RS18080 92a4666c952f901c0478071289551843 192 Gene3D G3DSA:1.10.10.10 135 191 1.0E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS18080 92a4666c952f901c0478071289551843 192 Pfam PF00072 Response regulator receiver domain 4 110 5.5E-7 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS18080 92a4666c952f901c0478071289551843 192 SMART SM00448 2 113 2.2E-6 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS18080 92a4666c952f901c0478071289551843 192 Gene3D G3DSA:3.40.50.2300 1 121 1.3E-14 T 13-09-2016 THL1_RS18080 92a4666c952f901c0478071289551843 192 PANTHER PTHR26402:SF567 2 187 3.1E-74 T 13-09-2016 THL1_RS18080 92a4666c952f901c0478071289551843 192 SUPERFAMILY SSF52172 1 184 4.7E-44 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS18080 92a4666c952f901c0478071289551843 192 SMART SM01012 129 184 2.7E-18 T 13-09-2016 IPR005561 ANTAR domain GO:0003723 THL1_RS18080 92a4666c952f901c0478071289551843 192 PANTHER PTHR26402 2 187 3.1E-74 T 13-09-2016 THL1_RS18080 92a4666c952f901c0478071289551843 192 PIRSF PIRSF036382 1 191 3.6E-64 T 13-09-2016 IPR008327 Signal transduction response regulator, antiterminator THL1_RS14550 99887008f56dc0f6456b3f343b0292b1 244 Gene3D G3DSA:3.90.1550.10 9 218 2.9E-44 T 13-09-2016 THL1_RS14550 99887008f56dc0f6456b3f343b0292b1 244 SUPERFAMILY SSF55681 7 217 4.06E-38 T 13-09-2016 THL1_RS06225 df2bffcd807ad535d4f90f5f76c3f3e7 301 SUPERFAMILY SSF103481 186 288 3.92E-11 T 13-09-2016 THL1_RS06225 df2bffcd807ad535d4f90f5f76c3f3e7 301 SUPERFAMILY SSF103481 35 138 3.27E-14 T 13-09-2016 THL1_RS06225 df2bffcd807ad535d4f90f5f76c3f3e7 301 PANTHER PTHR32322:SF8 1 289 6.1E-95 T 13-09-2016 THL1_RS06225 df2bffcd807ad535d4f90f5f76c3f3e7 301 Pfam PF00892 EamA-like transporter family 149 285 1.7E-15 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS06225 df2bffcd807ad535d4f90f5f76c3f3e7 301 Pfam PF00892 EamA-like transporter family 5 134 8.9E-12 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS06225 df2bffcd807ad535d4f90f5f76c3f3e7 301 PANTHER PTHR32322 1 289 6.1E-95 T 13-09-2016 THL1_RS24595 ae07ce4d74b9ec152fe9bc1537b7f0e4 286 PANTHER PTHR30222:SF6 21 265 3.2E-70 T 13-09-2016 THL1_RS24595 ae07ce4d74b9ec152fe9bc1537b7f0e4 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 268 5.5E-20 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS24595 ae07ce4d74b9ec152fe9bc1537b7f0e4 286 SUPERFAMILY SSF161098 10 275 5.42E-56 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS24595 ae07ce4d74b9ec152fe9bc1537b7f0e4 286 PANTHER PTHR30222 21 265 3.2E-70 T 13-09-2016 THL1_RS24595 ae07ce4d74b9ec152fe9bc1537b7f0e4 286 Gene3D G3DSA:1.10.3720.10 10 276 1.8E-60 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS28255 31c9adac9f41236cb65b16086eb188f2 726 PANTHER PTHR11070:SF7 8 722 1.7E-246 T 13-09-2016 THL1_RS28255 31c9adac9f41236cb65b16086eb188f2 726 TIGRFAM TIGR01075 uvrD: DNA helicase II 8 724 0.0 T 13-09-2016 IPR005753 DNA helicase, ATP-dependent, UvrD type GO:0004003|GO:0005737|GO:0006268 THL1_RS28255 31c9adac9f41236cb65b16086eb188f2 726 Gene3D G3DSA:3.40.50.300 288 389 1.7E-73 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28255 31c9adac9f41236cb65b16086eb188f2 726 Gene3D G3DSA:3.40.50.300 554 644 1.7E-73 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28255 31c9adac9f41236cb65b16086eb188f2 726 Pfam PF00580 UvrD/REP helicase N-terminal domain 12 273 3.9E-74 T 13-09-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 THL1_RS28255 31c9adac9f41236cb65b16086eb188f2 726 Gene3D G3DSA:3.40.50.300 193 287 3.4E-71 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28255 31c9adac9f41236cb65b16086eb188f2 726 Gene3D G3DSA:3.40.50.300 8 112 3.4E-71 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28255 31c9adac9f41236cb65b16086eb188f2 726 Gene3D G3DSA:1.10.10.160 116 192 2.9E-22 T 13-09-2016 IPR013986 DExx box DNA helicase domain THL1_RS28255 31c9adac9f41236cb65b16086eb188f2 726 Gene3D G3DSA:1.10.486.10 390 543 1.2E-48 T 13-09-2016 THL1_RS28255 31c9adac9f41236cb65b16086eb188f2 726 PANTHER PTHR11070 8 722 1.7E-246 T 13-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 THL1_RS28255 31c9adac9f41236cb65b16086eb188f2 726 Pfam PF13361 UvrD-like helicase C-terminal domain 279 618 9.2E-75 T 13-09-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 THL1_RS28255 31c9adac9f41236cb65b16086eb188f2 726 SUPERFAMILY SSF52540 9 644 2.3E-183 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22690 2b89b038c0d1e8561ab8847e5537953e 864 SUPERFAMILY SSF53448 404 663 3.32E-50 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS22690 2b89b038c0d1e8561ab8847e5537953e 864 PANTHER PTHR10587 329 592 1.3E-80 T 13-09-2016 THL1_RS22690 2b89b038c0d1e8561ab8847e5537953e 864 PANTHER PTHR10587:SF64 329 592 1.3E-80 T 13-09-2016 THL1_RS22690 2b89b038c0d1e8561ab8847e5537953e 864 Gene3D G3DSA:3.90.550.10 421 667 6.8E-33 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS22690 2b89b038c0d1e8561ab8847e5537953e 864 Pfam PF13641 Glycosyltransferase like family 2 421 649 6.1E-33 T 13-09-2016 THL1_RS22690 2b89b038c0d1e8561ab8847e5537953e 864 Gene3D G3DSA:3.20.20.80 55 302 2.2E-32 T 13-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 THL1_RS22690 2b89b038c0d1e8561ab8847e5537953e 864 SUPERFAMILY SSF51445 40 302 4.99E-51 T 13-09-2016 IPR017853 Glycoside hydrolase superfamily THL1_RS19785 aef79ddc7d8d97f984a175b40ccd62ac 260 PANTHER PTHR11941 1 257 5.5E-81 T 13-09-2016 THL1_RS19785 aef79ddc7d8d97f984a175b40ccd62ac 260 SUPERFAMILY SSF52096 4 260 5.73E-78 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS19785 aef79ddc7d8d97f984a175b40ccd62ac 260 Gene3D G3DSA:1.10.12.10 202 260 1.0E-16 T 13-09-2016 IPR014748 Crontonase, C-terminal THL1_RS19785 aef79ddc7d8d97f984a175b40ccd62ac 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 259 7.7E-54 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS19785 aef79ddc7d8d97f984a175b40ccd62ac 260 PANTHER PTHR11941:SF45 1 257 5.5E-81 T 13-09-2016 THL1_RS19785 aef79ddc7d8d97f984a175b40ccd62ac 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 13-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THL1_RS19785 aef79ddc7d8d97f984a175b40ccd62ac 260 Gene3D G3DSA:3.90.226.10 4 200 8.7E-63 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS10925 2ec5061fb846f5858247f1eff7646cc4 151 PANTHER PTHR12418 1 139 9.1E-44 T 13-09-2016 THL1_RS10925 2ec5061fb846f5858247f1eff7646cc4 151 PANTHER PTHR12418:SF28 1 139 9.1E-44 T 13-09-2016 THL1_RS10925 2ec5061fb846f5858247f1eff7646cc4 151 SUPERFAMILY SSF54637 1 139 2.42E-26 T 13-09-2016 IPR029069 HotDog domain THL1_RS10925 2ec5061fb846f5858247f1eff7646cc4 151 Pfam PF03061 Thioesterase superfamily 52 126 6.1E-9 T 13-09-2016 IPR006683 Thioesterase domain THL1_RS10925 2ec5061fb846f5858247f1eff7646cc4 151 Gene3D G3DSA:3.10.129.10 9 140 1.3E-26 T 13-09-2016 IPR029069 HotDog domain THL1_RS10925 2ec5061fb846f5858247f1eff7646cc4 151 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 20 112 3.1E-12 T 13-09-2016 IPR003736 Phenylacetic acid degradation-related domain THL1_RS07225 63fc9b7020f8137ed4ff0665df858af8 207 PANTHER PTHR14119 4 202 4.8E-121 T 13-09-2016 THL1_RS07225 63fc9b7020f8137ed4ff0665df858af8 207 Gene3D G3DSA:3.40.50.850 5 204 7.6E-50 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS07225 63fc9b7020f8137ed4ff0665df858af8 207 PANTHER PTHR14119:SF11 4 202 4.8E-121 T 13-09-2016 THL1_RS07225 63fc9b7020f8137ed4ff0665df858af8 207 Pfam PF00857 Isochorismatase family 14 165 4.1E-23 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS07225 63fc9b7020f8137ed4ff0665df858af8 207 SUPERFAMILY SSF52499 5 202 2.35E-54 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS09330 e4c10f6b625698b672732749d80c60eb 450 PANTHER PTHR30386:SF4 3 130 2.3E-142 T 13-09-2016 THL1_RS09330 e4c10f6b625698b672732749d80c60eb 450 PANTHER PTHR30386:SF4 161 450 2.3E-142 T 13-09-2016 THL1_RS09330 e4c10f6b625698b672732749d80c60eb 450 ProSitePatterns PS00543 HlyD family secretion proteins signature. 414 436 - T 13-09-2016 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 THL1_RS09330 e4c10f6b625698b672732749d80c60eb 450 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 371 394 5.4E-43 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS09330 e4c10f6b625698b672732749d80c60eb 450 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 87 107 5.4E-43 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS09330 e4c10f6b625698b672732749d80c60eb 450 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 414 429 5.4E-43 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS09330 e4c10f6b625698b672732749d80c60eb 450 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 429 449 5.4E-43 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS09330 e4c10f6b625698b672732749d80c60eb 450 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 347 371 5.4E-43 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS09330 e4c10f6b625698b672732749d80c60eb 450 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 45 68 5.4E-43 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS09330 e4c10f6b625698b672732749d80c60eb 450 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 314 335 5.4E-43 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS09330 e4c10f6b625698b672732749d80c60eb 450 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 35 450 5.9E-130 T 13-09-2016 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 THL1_RS09330 e4c10f6b625698b672732749d80c60eb 450 PANTHER PTHR30386 161 450 2.3E-142 T 13-09-2016 THL1_RS09330 e4c10f6b625698b672732749d80c60eb 450 PANTHER PTHR30386 3 130 2.3E-142 T 13-09-2016 THL1_RS09330 e4c10f6b625698b672732749d80c60eb 450 Pfam PF13437 HlyD family secretion protein 301 411 4.1E-16 T 13-09-2016 THL1_RS09330 e4c10f6b625698b672732749d80c60eb 450 Gene3D G3DSA:2.40.50.100 299 333 4.3E-16 T 13-09-2016 THL1_RS09330 e4c10f6b625698b672732749d80c60eb 450 Gene3D G3DSA:2.40.50.100 79 109 4.3E-16 T 13-09-2016 THL1_RS08385 0e9de0767c882335b285b14a9eaaea40 999 Gene3D G3DSA:3.40.710.10 805 965 7.0E-43 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS08385 0e9de0767c882335b285b14a9eaaea40 999 Gene3D G3DSA:3.40.710.10 351 489 7.0E-43 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS08385 0e9de0767c882335b285b14a9eaaea40 999 Gene3D G3DSA:3.40.710.10 536 619 7.0E-43 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS08385 0e9de0767c882335b285b14a9eaaea40 999 SUPERFAMILY SSF53955 128 280 2.28E-9 T 13-09-2016 IPR023346 Lysozyme-like domain THL1_RS08385 0e9de0767c882335b285b14a9eaaea40 999 SUPERFAMILY SSF56601 708 980 9.39E-28 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS08385 0e9de0767c882335b285b14a9eaaea40 999 SUPERFAMILY SSF56601 537 595 5.63E-5 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS08385 0e9de0767c882335b285b14a9eaaea40 999 Gene3D G3DSA:1.10.3810.10 123 279 1.6E-8 T 13-09-2016 THL1_RS08385 0e9de0767c882335b285b14a9eaaea40 999 Pfam PF00912 Transglycosylase 118 316 2.6E-27 T 13-09-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 THL1_RS08485 3742370049982a8266964b22ec43d52b 367 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 6 30 2.1E-5 T 13-09-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THL1_RS08485 3742370049982a8266964b22ec43d52b 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 311 337 1.3E-5 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS08485 3742370049982a8266964b22ec43d52b 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 139 155 1.3E-5 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS08485 3742370049982a8266964b22ec43d52b 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 67 88 1.3E-5 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS08485 3742370049982a8266964b22ec43d52b 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 164 178 1.3E-5 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS08485 3742370049982a8266964b22ec43d52b 367 SUPERFAMILY SSF53850 41 365 3.62E-55 T 13-09-2016 THL1_RS08485 3742370049982a8266964b22ec43d52b 367 Gene3D G3DSA:3.40.190.10 40 153 4.0E-21 T 13-09-2016 THL1_RS08485 3742370049982a8266964b22ec43d52b 367 Gene3D G3DSA:3.40.190.10 276 330 4.0E-21 T 13-09-2016 THL1_RS08485 3742370049982a8266964b22ec43d52b 367 Gene3D G3DSA:3.40.190.10 154 251 2.1E-8 T 13-09-2016 THL1_RS08485 3742370049982a8266964b22ec43d52b 367 PANTHER PTHR30006 1 365 1.5E-28 T 13-09-2016 THL1_RS08485 3742370049982a8266964b22ec43d52b 367 Pfam PF13416 Bacterial extracellular solute-binding protein 61 326 2.2E-20 T 13-09-2016 THL1_RS02120 31adf8d95a07a72e8d4cf9f4882fa3c3 175 SMART SM00448 26 139 5.7E-21 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02120 31adf8d95a07a72e8d4cf9f4882fa3c3 175 Pfam PF00072 Response regulator receiver domain 28 139 4.3E-19 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02120 31adf8d95a07a72e8d4cf9f4882fa3c3 175 Gene3D G3DSA:3.40.50.2300 24 143 1.9E-27 T 13-09-2016 THL1_RS02120 31adf8d95a07a72e8d4cf9f4882fa3c3 175 PANTHER PTHR26402 26 140 2.0E-28 T 13-09-2016 THL1_RS02120 31adf8d95a07a72e8d4cf9f4882fa3c3 175 SUPERFAMILY SSF52172 25 144 2.13E-30 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS23955 0999863ea714201d2bd60ade55bca547 171 PIRSF PIRSF029681 1 171 1.4E-49 T 13-09-2016 IPR018550 Lipid A 3-O-deacylase-related THL1_RS23955 0999863ea714201d2bd60ade55bca547 171 SUPERFAMILY SSF56925 17 161 4.97E-8 T 13-09-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 THL1_RS23955 0999863ea714201d2bd60ade55bca547 171 Gene3D G3DSA:2.40.160.20 25 171 9.1E-51 T 13-09-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 THL1_RS23955 0999863ea714201d2bd60ade55bca547 171 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 59 169 1.3E-26 T 13-09-2016 IPR018550 Lipid A 3-O-deacylase-related THL1_RS11180 f0247cbb90921a545bef842daea58614 459 Pfam PF00474 Sodium:solute symporter family 32 412 5.1E-38 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS11180 f0247cbb90921a545bef842daea58614 459 PANTHER PTHR11819:SF141 1 453 1.2E-170 T 13-09-2016 THL1_RS11180 f0247cbb90921a545bef842daea58614 459 PANTHER PTHR11819 1 453 1.2E-170 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS18320 8918662df1e1a99ed61dfe75a24d66a3 205 PANTHER PTHR30086:SF12 1 205 2.0E-83 T 13-09-2016 THL1_RS18320 8918662df1e1a99ed61dfe75a24d66a3 205 Pfam PF01810 LysE type translocator 15 191 4.0E-20 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS18320 8918662df1e1a99ed61dfe75a24d66a3 205 PANTHER PTHR30086 1 205 2.0E-83 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS23360 31210ac8c923653237275684698afc47 444 Pfam PF09375 Imelysin 65 420 4.0E-96 T 13-09-2016 THL1_RS15580 7bdb6af0d53cd29e1f9be81351969b73 409 Gene3D G3DSA:1.20.140.10 235 399 7.5E-48 T 13-09-2016 THL1_RS15580 7bdb6af0d53cd29e1f9be81351969b73 409 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 132 233 1.2E-20 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS15580 7bdb6af0d53cd29e1f9be81351969b73 409 SUPERFAMILY SSF56645 1 258 1.57E-72 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS15580 7bdb6af0d53cd29e1f9be81351969b73 409 Gene3D G3DSA:2.40.110.10 131 234 1.5E-40 T 13-09-2016 THL1_RS15580 7bdb6af0d53cd29e1f9be81351969b73 409 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 128 2.9E-17 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS15580 7bdb6af0d53cd29e1f9be81351969b73 409 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 393 6.9E-33 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS15580 7bdb6af0d53cd29e1f9be81351969b73 409 Gene3D G3DSA:1.10.540.10 1 130 5.7E-38 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS15580 7bdb6af0d53cd29e1f9be81351969b73 409 SUPERFAMILY SSF47203 243 402 2.42E-44 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS15580 7bdb6af0d53cd29e1f9be81351969b73 409 PANTHER PTHR10909 1 396 1.3E-237 T 13-09-2016 THL1_RS15580 7bdb6af0d53cd29e1f9be81351969b73 409 PANTHER PTHR10909:SF282 1 396 1.3E-237 T 13-09-2016 THL1_RS27050 9403595e25b23a5f5052e81341e44908 773 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 17 766 3.0E-284 T 13-09-2016 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 THL1_RS27050 9403595e25b23a5f5052e81341e44908 773 PIRSF PIRSF000144 1 770 0.0 T 13-09-2016 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 THL1_RS27050 9403595e25b23a5f5052e81341e44908 773 Pfam PF00384 Molybdopterin oxidoreductase 113 495 2.9E-26 T 13-09-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 THL1_RS27050 9403595e25b23a5f5052e81341e44908 773 SUPERFAMILY SSF53706 51 633 3.93E-142 T 13-09-2016 THL1_RS27050 9403595e25b23a5f5052e81341e44908 773 Gene3D G3DSA:3.40.50.740 113 186 3.3E-57 T 13-09-2016 THL1_RS27050 9403595e25b23a5f5052e81341e44908 773 Gene3D G3DSA:3.40.50.740 399 629 3.3E-57 T 13-09-2016 THL1_RS27050 9403595e25b23a5f5052e81341e44908 773 PANTHER PTHR11615:SF114 275 773 0.0 T 13-09-2016 THL1_RS27050 9403595e25b23a5f5052e81341e44908 773 PANTHER PTHR11615:SF114 53 256 0.0 T 13-09-2016 THL1_RS27050 9403595e25b23a5f5052e81341e44908 773 Gene3D G3DSA:3.40.228.10 187 398 6.6E-53 T 13-09-2016 THL1_RS27050 9403595e25b23a5f5052e81341e44908 773 Pfam PF01568 Molydopterin dinucleotide binding domain 652 716 3.1E-5 T 13-09-2016 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 THL1_RS27050 9403595e25b23a5f5052e81341e44908 773 Gene3D G3DSA:2.40.40.20 648 709 1.3E-4 T 13-09-2016 THL1_RS27050 9403595e25b23a5f5052e81341e44908 773 SUPERFAMILY SSF50692 648 767 2.98E-12 T 13-09-2016 IPR009010 Aspartate decarboxylase-like domain THL1_RS27050 9403595e25b23a5f5052e81341e44908 773 PANTHER PTHR11615 275 773 0.0 T 13-09-2016 THL1_RS27050 9403595e25b23a5f5052e81341e44908 773 PANTHER PTHR11615 53 256 0.0 T 13-09-2016 THL1_RS19515 aa6c1e7c2c5b1e3964cd3a4a2d8a0d8f 277 PANTHER PTHR13696:SF3 1 259 4.2E-119 T 13-09-2016 THL1_RS19515 aa6c1e7c2c5b1e3964cd3a4a2d8a0d8f 277 Gene3D G3DSA:3.40.50.300 9 268 3.2E-58 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS19515 aa6c1e7c2c5b1e3964cd3a4a2d8a0d8f 277 PANTHER PTHR13696 1 259 4.2E-119 T 13-09-2016 THL1_RS19515 aa6c1e7c2c5b1e3964cd3a4a2d8a0d8f 277 PIRSF PIRSF003092 4 273 9.6E-83 T 13-09-2016 IPR025501 ATP binding protein MinD THL1_RS19515 aa6c1e7c2c5b1e3964cd3a4a2d8a0d8f 277 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 8 247 1.3E-25 T 13-09-2016 IPR019591 Mrp/NBP35 ATP-binding protein THL1_RS19515 aa6c1e7c2c5b1e3964cd3a4a2d8a0d8f 277 SUPERFAMILY SSF52540 8 267 1.04E-55 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10380 fb1411efaf8236c4cb28799c594b51c3 225 SMART SM00421 162 219 2.8E-21 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS10380 fb1411efaf8236c4cb28799c594b51c3 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 195 207 5.5E-12 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS10380 fb1411efaf8236c4cb28799c594b51c3 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 195 5.5E-12 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS10380 fb1411efaf8236c4cb28799c594b51c3 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 179 5.5E-12 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS10380 fb1411efaf8236c4cb28799c594b51c3 225 PANTHER PTHR26402:SF151 19 222 3.8E-65 T 13-09-2016 THL1_RS10380 fb1411efaf8236c4cb28799c594b51c3 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 164 219 2.8E-20 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS10380 fb1411efaf8236c4cb28799c594b51c3 225 PANTHER PTHR26402 19 222 3.8E-65 T 13-09-2016 THL1_RS10380 fb1411efaf8236c4cb28799c594b51c3 225 SMART SM00448 19 131 2.4E-30 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS10380 fb1411efaf8236c4cb28799c594b51c3 225 ProSitePatterns PS00622 LuxR-type HTH domain signature. 179 206 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS10380 fb1411efaf8236c4cb28799c594b51c3 225 Gene3D G3DSA:3.40.50.2300 19 136 2.1E-32 T 13-09-2016 THL1_RS10380 fb1411efaf8236c4cb28799c594b51c3 225 SUPERFAMILY SSF52172 19 193 7.26E-32 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS10380 fb1411efaf8236c4cb28799c594b51c3 225 Gene3D G3DSA:1.10.10.10 137 224 9.2E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS10380 fb1411efaf8236c4cb28799c594b51c3 225 Pfam PF00072 Response regulator receiver domain 21 131 5.2E-28 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS07780 563a45436ef172664f5a2e35b1de2f81 233 Gene3D G3DSA:1.10.10.10 15 74 2.7E-14 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07780 563a45436ef172664f5a2e35b1de2f81 233 SUPERFAMILY SSF46785 15 76 1.52E-13 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07780 563a45436ef172664f5a2e35b1de2f81 233 SUPERFAMILY SSF48008 77 218 5.75E-21 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS07780 563a45436ef172664f5a2e35b1de2f81 233 Pfam PF07729 FCD domain 82 213 6.8E-22 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS07780 563a45436ef172664f5a2e35b1de2f81 233 SMART SM00895 82 214 2.2E-17 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS07780 563a45436ef172664f5a2e35b1de2f81 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 72 2.0E-13 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS07780 563a45436ef172664f5a2e35b1de2f81 233 Gene3D G3DSA:1.20.120.530 75 224 6.1E-29 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS07780 563a45436ef172664f5a2e35b1de2f81 233 PANTHER PTHR11751 15 98 2.1E-19 T 13-09-2016 THL1_RS07780 563a45436ef172664f5a2e35b1de2f81 233 SMART SM00345 14 72 1.2E-16 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 Pfam PF00012 Hsp70 protein 100 230 8.3E-11 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 Pfam PF00012 Hsp70 protein 299 395 1.4E-8 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 PRINTS PR00301 70kDa heat shock protein signature 8 21 2.4E-6 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 PRINTS PR00301 70kDa heat shock protein signature 36 48 2.4E-6 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 PRINTS PR00301 70kDa heat shock protein signature 124 144 2.4E-6 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 PRINTS PR00301 70kDa heat shock protein signature 190 200 2.4E-6 T 13-09-2016 IPR013126 Heat shock protein 70 family THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 Gene3D G3DSA:3.30.420.40 356 396 2.4E-14 T 13-09-2016 THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 Gene3D G3DSA:3.30.420.40 188 225 2.4E-14 T 13-09-2016 THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 184 197 - T 13-09-2016 IPR018181 Heat shock protein 70, conserved site THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 SUPERFAMILY SSF53067 9 175 3.63E-30 T 13-09-2016 THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 Gene3D G3DSA:3.30.420.40 9 72 3.0E-30 T 13-09-2016 THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 Gene3D G3DSA:3.30.420.40 105 187 3.0E-30 T 13-09-2016 THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 PANTHER PTHR19375 290 414 1.4E-126 T 13-09-2016 THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 374 388 - T 13-09-2016 IPR018181 Heat shock protein 70, conserved site THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 PANTHER PTHR19375 7 240 1.4E-126 T 13-09-2016 THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 PANTHER PTHR19375:SF182 290 414 1.4E-126 T 13-09-2016 THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 PANTHER PTHR19375:SF182 7 240 1.4E-126 T 13-09-2016 THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 SUPERFAMILY SSF53067 179 247 3.89E-33 T 13-09-2016 THL1_RS25610 9adad84a25d06b1b46b1dbaa162a344c 421 SUPERFAMILY SSF53067 296 416 3.89E-33 T 13-09-2016 THL1_RS01700 db085bdd8c05f3423d34aa08b1334c73 725 Pfam PF13515 Fusaric acid resistance protein-like 413 529 6.7E-22 T 13-09-2016 THL1_RS01700 db085bdd8c05f3423d34aa08b1334c73 725 TIGRFAM TIGR01667 YCCS_YHJK: integral membrane protein, YccS/YhfK family 12 717 3.5E-279 T 13-09-2016 IPR010020 Integral membrane protein, YccS/YhfK THL1_RS01700 db085bdd8c05f3423d34aa08b1334c73 725 Pfam PF12805 FUSC-like inner membrane protein yccS 70 354 1.7E-113 T 13-09-2016 IPR032692 Integral membrane protein YccS, N-terminal THL1_RS01700 db085bdd8c05f3423d34aa08b1334c73 725 PANTHER PTHR30509 5 685 2.4E-297 T 13-09-2016 THL1_RS01700 db085bdd8c05f3423d34aa08b1334c73 725 PANTHER PTHR30509:SF8 5 685 2.4E-297 T 13-09-2016 THL1_RS01700 db085bdd8c05f3423d34aa08b1334c73 725 TIGRFAM TIGR01666 YCCS: TIGR01666 family membrane protein 14 715 1.1E-227 T 13-09-2016 IPR010019 Integral membrane protein, YccS THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 85 5.3E-15 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 13-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 PANTHER PTHR19370:SF128 5 332 5.1E-61 T 13-09-2016 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 SUPERFAMILY SSF52343 204 333 1.83E-34 T 13-09-2016 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 136 148 5.0E-25 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 153 160 5.0E-25 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 211 230 5.0E-25 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 236 245 5.0E-25 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 196 205 5.0E-25 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 PRINTS PR00410 Phenol hydroxylase reductase family signature 300 308 5.0E-25 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 PANTHER PTHR19370 5 332 5.1E-61 T 13-09-2016 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 SUPERFAMILY SSF54292 1 100 4.72E-27 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 Pfam PF00175 Oxidoreductase NAD-binding domain 212 314 1.2E-21 T 13-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 Gene3D G3DSA:3.10.20.30 2 100 9.0E-27 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 SUPERFAMILY SSF63380 76 204 8.51E-24 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 Pfam PF00970 Oxidoreductase FAD-binding domain 110 202 8.7E-18 T 13-09-2016 IPR008333 Oxidoreductase, FAD-binding domain THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 153 160 1.8E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 300 308 1.8E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 211 230 1.8E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 Gene3D G3DSA:2.40.30.10 106 198 1.2E-22 T 13-09-2016 THL1_RS14400 0e740dc11b0f8657bf45a389a07ba09d 337 Gene3D G3DSA:3.40.50.80 205 333 9.3E-36 T 13-09-2016 THL1_RS14505 2aa261c7f54c5b320337d0f88f588802 252 PANTHER PTHR30060 1 240 2.3E-117 T 13-09-2016 THL1_RS14505 2aa261c7f54c5b320337d0f88f588802 252 PANTHER PTHR30060:SF1 1 240 2.3E-117 T 13-09-2016 THL1_RS14505 2aa261c7f54c5b320337d0f88f588802 252 Pfam PF03741 Integral membrane protein TerC family 14 204 2.8E-49 T 13-09-2016 IPR005496 Integral membrane protein TerC GO:0016021 THL1_RS13685 cf0f681f11c2fda6f976282b2ef3fe85 496 PANTHER PTHR11699:SF144 24 496 4.6E-269 T 13-09-2016 THL1_RS13685 cf0f681f11c2fda6f976282b2ef3fe85 496 SUPERFAMILY SSF53720 17 483 7.46E-130 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS13685 cf0f681f11c2fda6f976282b2ef3fe85 496 Gene3D G3DSA:3.40.605.10 17 265 7.3E-72 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS13685 cf0f681f11c2fda6f976282b2ef3fe85 496 Gene3D G3DSA:3.40.309.10 266 444 5.0E-50 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS13685 cf0f681f11c2fda6f976282b2ef3fe85 496 PANTHER PTHR11699 24 496 4.6E-269 T 13-09-2016 THL1_RS13685 cf0f681f11c2fda6f976282b2ef3fe85 496 Pfam PF00171 Aldehyde dehydrogenase family 20 478 6.3E-127 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS13685 cf0f681f11c2fda6f976282b2ef3fe85 496 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS14645 4762838600c08e89c609596daa62f3bf 247 PANTHER PTHR31272:SF4 1 238 1.1E-75 T 13-09-2016 THL1_RS14645 4762838600c08e89c609596daa62f3bf 247 PANTHER PTHR31272 1 238 1.1E-75 T 13-09-2016 THL1_RS14645 4762838600c08e89c609596daa62f3bf 247 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 11 225 2.6E-58 T 13-09-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 THL1_RS11020 e414e910c9495cc56ade6dbc3a3528a7 267 Pfam PF12833 Helix-turn-helix domain 189 267 5.7E-21 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS11020 e414e910c9495cc56ade6dbc3a3528a7 267 SUPERFAMILY SSF46689 170 217 1.16E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS11020 e414e910c9495cc56ade6dbc3a3528a7 267 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 234 249 1.5E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS11020 e414e910c9495cc56ade6dbc3a3528a7 267 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 249 265 1.5E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS11020 e414e910c9495cc56ade6dbc3a3528a7 267 PANTHER PTHR11019:SF94 1 267 3.7E-111 T 13-09-2016 THL1_RS11020 e414e910c9495cc56ade6dbc3a3528a7 267 Gene3D G3DSA:2.60.120.280 19 137 3.6E-17 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS11020 e414e910c9495cc56ade6dbc3a3528a7 267 SMART SM00342 183 265 1.1E-23 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS11020 e414e910c9495cc56ade6dbc3a3528a7 267 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 220 261 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS11020 e414e910c9495cc56ade6dbc3a3528a7 267 Gene3D G3DSA:1.10.10.60 221 267 4.3E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS11020 e414e910c9495cc56ade6dbc3a3528a7 267 Gene3D G3DSA:1.10.10.60 170 220 2.5E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS11020 e414e910c9495cc56ade6dbc3a3528a7 267 SUPERFAMILY SSF46689 219 267 1.43E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS11020 e414e910c9495cc56ade6dbc3a3528a7 267 SUPERFAMILY SSF51215 18 135 3.27E-22 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS11020 e414e910c9495cc56ade6dbc3a3528a7 267 PANTHER PTHR11019 1 267 3.7E-111 T 13-09-2016 THL1_RS11020 e414e910c9495cc56ade6dbc3a3528a7 267 Pfam PF02311 AraC-like ligand binding domain 12 141 1.5E-25 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS06465 ffe0cadd60ae6dd3aab087d3082f94ba 473 Gene3D G3DSA:3.90.1150.10 350 467 1.4E-6 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS06465 ffe0cadd60ae6dd3aab087d3082f94ba 473 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 2.0E-13 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS06465 ffe0cadd60ae6dd3aab087d3082f94ba 473 SMART SM00345 7 66 9.4E-13 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS06465 ffe0cadd60ae6dd3aab087d3082f94ba 473 PANTHER PTHR11751:SF314 86 467 4.1E-187 T 13-09-2016 THL1_RS06465 ffe0cadd60ae6dd3aab087d3082f94ba 473 PANTHER PTHR11751 86 467 4.1E-187 T 13-09-2016 THL1_RS06465 ffe0cadd60ae6dd3aab087d3082f94ba 473 SUPERFAMILY SSF46785 2 69 8.91E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS06465 ffe0cadd60ae6dd3aab087d3082f94ba 473 SUPERFAMILY SSF53383 98 468 3.3E-93 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS06465 ffe0cadd60ae6dd3aab087d3082f94ba 473 Pfam PF00155 Aminotransferase class I and II 147 449 6.1E-27 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS06465 ffe0cadd60ae6dd3aab087d3082f94ba 473 Gene3D G3DSA:3.40.640.10 145 349 1.5E-66 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS06465 ffe0cadd60ae6dd3aab087d3082f94ba 473 Gene3D G3DSA:1.10.10.10 1 68 4.4E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS04560 00782e9ad6c2786f18ba08f1c89ef366 408 PANTHER PTHR10617:SF103 8 306 3.7E-53 T 13-09-2016 THL1_RS04560 00782e9ad6c2786f18ba08f1c89ef366 408 SUPERFAMILY SSF51905 8 196 1.81E-47 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS04560 00782e9ad6c2786f18ba08f1c89ef366 408 SUPERFAMILY SSF51905 345 404 1.81E-47 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS04560 00782e9ad6c2786f18ba08f1c89ef366 408 PANTHER PTHR10617 338 408 3.7E-53 T 13-09-2016 THL1_RS04560 00782e9ad6c2786f18ba08f1c89ef366 408 PANTHER PTHR10617 8 306 3.7E-53 T 13-09-2016 THL1_RS04560 00782e9ad6c2786f18ba08f1c89ef366 408 SUPERFAMILY SSF160996 209 346 5.23E-10 T 13-09-2016 THL1_RS04560 00782e9ad6c2786f18ba08f1c89ef366 408 Pfam PF03486 HI0933-like protein 8 399 1.3E-110 T 13-09-2016 THL1_RS04560 00782e9ad6c2786f18ba08f1c89ef366 408 PRINTS PR00419 Adrenodoxin reductase family signature 30 43 1.1E-5 T 13-09-2016 THL1_RS04560 00782e9ad6c2786f18ba08f1c89ef366 408 PRINTS PR00419 Adrenodoxin reductase family signature 7 29 1.1E-5 T 13-09-2016 THL1_RS04560 00782e9ad6c2786f18ba08f1c89ef366 408 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 29 405 6.0E-163 T 13-09-2016 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 THL1_RS04560 00782e9ad6c2786f18ba08f1c89ef366 408 PANTHER PTHR10617:SF103 338 408 3.7E-53 T 13-09-2016 THL1_RS04560 00782e9ad6c2786f18ba08f1c89ef366 408 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 8 399 5.1E-85 T 13-09-2016 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like THL1_RS04560 00782e9ad6c2786f18ba08f1c89ef366 408 Gene3D G3DSA:3.50.50.60 347 402 8.9E-40 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS04560 00782e9ad6c2786f18ba08f1c89ef366 408 Gene3D G3DSA:3.50.50.60 8 192 8.9E-40 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS06330 4121b2a049533ce7308d1b75f032bd54 463 SUPERFAMILY SSF88723 12 74 6.47E-14 T 13-09-2016 IPR029060 PIN domain-like THL1_RS06330 4121b2a049533ce7308d1b75f032bd54 463 SUPERFAMILY SSF88723 110 160 6.47E-14 T 13-09-2016 IPR029060 PIN domain-like THL1_RS06330 4121b2a049533ce7308d1b75f032bd54 463 PANTHER PTHR30473:SF2 206 458 7.2E-201 T 13-09-2016 THL1_RS06330 4121b2a049533ce7308d1b75f032bd54 463 Gene3D G3DSA:3.40.50.300 251 460 1.1E-54 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06330 4121b2a049533ce7308d1b75f032bd54 463 Gene3D G3DSA:3.40.50.1010 110 163 2.3E-12 T 13-09-2016 IPR029060 PIN domain-like THL1_RS06330 4121b2a049533ce7308d1b75f032bd54 463 Gene3D G3DSA:3.40.50.1010 16 73 2.3E-12 T 13-09-2016 IPR029060 PIN domain-like THL1_RS06330 4121b2a049533ce7308d1b75f032bd54 463 Pfam PF13638 PIN domain 16 160 1.6E-37 T 13-09-2016 IPR002716 PIN domain THL1_RS06330 4121b2a049533ce7308d1b75f032bd54 463 SUPERFAMILY SSF52540 205 442 7.39E-30 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06330 4121b2a049533ce7308d1b75f032bd54 463 PANTHER PTHR30473:SF2 12 187 7.2E-201 T 13-09-2016 THL1_RS06330 4121b2a049533ce7308d1b75f032bd54 463 PANTHER PTHR30473 206 458 7.2E-201 T 13-09-2016 THL1_RS06330 4121b2a049533ce7308d1b75f032bd54 463 Pfam PF02562 PhoH-like protein 254 450 2.0E-45 T 13-09-2016 IPR003714 PhoH-like protein GO:0005524 THL1_RS06330 4121b2a049533ce7308d1b75f032bd54 463 PANTHER PTHR30473 12 187 7.2E-201 T 13-09-2016 THL1_RS06330 4121b2a049533ce7308d1b75f032bd54 463 SMART SM00670 13 147 2.3E-7 T 13-09-2016 IPR002716 PIN domain THL1_RS18440 44b4a2cbb153b52d0b260dae07d006bc 477 Pfam PF00155 Aminotransferase class I and II 139 449 3.4E-26 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS18440 44b4a2cbb153b52d0b260dae07d006bc 477 Gene3D G3DSA:1.10.10.10 6 73 3.8E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS18440 44b4a2cbb153b52d0b260dae07d006bc 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 69 1.1E-18 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS18440 44b4a2cbb153b52d0b260dae07d006bc 477 PANTHER PTHR11751:SF314 88 467 1.2E-168 T 13-09-2016 THL1_RS18440 44b4a2cbb153b52d0b260dae07d006bc 477 PANTHER PTHR11751 88 467 1.2E-168 T 13-09-2016 THL1_RS18440 44b4a2cbb153b52d0b260dae07d006bc 477 SMART SM00345 10 69 6.0E-21 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS18440 44b4a2cbb153b52d0b260dae07d006bc 477 Gene3D G3DSA:3.40.640.10 140 349 1.9E-61 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS18440 44b4a2cbb153b52d0b260dae07d006bc 477 SUPERFAMILY SSF53383 94 471 6.81E-89 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS18440 44b4a2cbb153b52d0b260dae07d006bc 477 SUPERFAMILY SSF46785 4 73 3.32E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS18440 44b4a2cbb153b52d0b260dae07d006bc 477 Gene3D G3DSA:3.90.1150.10 350 449 6.2E-5 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS26205 75171964d21aee8511c32dc0d954c85f 228 PANTHER PTHR10173 1 208 2.3E-110 T 13-09-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 THL1_RS26205 75171964d21aee8511c32dc0d954c85f 228 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 51 204 1.1E-62 T 13-09-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 THL1_RS26205 75171964d21aee8511c32dc0d954c85f 228 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 49 210 37.038 T 13-09-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 THL1_RS26205 75171964d21aee8511c32dc0d954c85f 228 PANTHER PTHR10173:SF36 1 208 2.3E-110 T 13-09-2016 THL1_RS26205 75171964d21aee8511c32dc0d954c85f 228 Gene3D G3DSA:3.30.1060.10 14 204 2.7E-77 T 13-09-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 THL1_RS26205 75171964d21aee8511c32dc0d954c85f 228 SUPERFAMILY SSF55068 11 213 3.4E-80 T 13-09-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 THL1_RS26205 75171964d21aee8511c32dc0d954c85f 228 Pfam PF01625 Peptide methionine sulfoxide reductase 52 204 1.6E-63 T 13-09-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 THL1_RS04655 fbd4b647f7b46f8004ef98af315686b1 479 PIRSF PIRSF006446 2 462 5.3E-232 T 13-09-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 THL1_RS04655 fbd4b647f7b46f8004ef98af315686b1 479 PANTHER PTHR30365:SF8 1 456 1.7E-287 T 13-09-2016 THL1_RS04655 fbd4b647f7b46f8004ef98af315686b1 479 PANTHER PTHR30365 1 456 1.7E-287 T 13-09-2016 THL1_RS04655 fbd4b647f7b46f8004ef98af315686b1 479 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 437 2.8E-171 T 13-09-2016 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0016020 THL1_RS26010 933b453940e6e06819b3fc1578af5a2f 479 Gene3D G3DSA:1.20.1600.10 30 441 1.2E-83 T 13-09-2016 THL1_RS26010 933b453940e6e06819b3fc1578af5a2f 479 PANTHER PTHR30026 1 460 3.2E-126 T 13-09-2016 THL1_RS26010 933b453940e6e06819b3fc1578af5a2f 479 PANTHER PTHR30026:SF3 1 460 3.2E-126 T 13-09-2016 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 THL1_RS26010 933b453940e6e06819b3fc1578af5a2f 479 SUPERFAMILY SSF56954 32 449 2.22E-93 T 13-09-2016 THL1_RS26010 933b453940e6e06819b3fc1578af5a2f 479 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 29 448 3.1E-128 T 13-09-2016 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 THL1_RS26010 933b453940e6e06819b3fc1578af5a2f 479 Pfam PF02321 Outer membrane efflux protein 244 436 1.3E-33 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS26010 933b453940e6e06819b3fc1578af5a2f 479 Pfam PF02321 Outer membrane efflux protein 34 210 2.3E-29 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS23235 97682686d08dd1dd5a06f1c91c7f07ed 193 PANTHER PTHR38764:SF1 2 186 5.4E-72 T 13-09-2016 THL1_RS23235 97682686d08dd1dd5a06f1c91c7f07ed 193 Pfam PF04336 Protein of unknown function, DUF479 81 183 1.3E-32 T 13-09-2016 IPR007431 Acyl carrier protein phosphodiesterase GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 THL1_RS23235 97682686d08dd1dd5a06f1c91c7f07ed 193 PIRSF PIRSF011489 1 192 8.1E-78 T 13-09-2016 IPR007431 Acyl carrier protein phosphodiesterase GO:0006633|GO:0008770 KEGG: 00770+3.1.4.14|MetaCyc: PWY-6012 THL1_RS23235 97682686d08dd1dd5a06f1c91c7f07ed 193 PANTHER PTHR38764 2 186 5.4E-72 T 13-09-2016 THL1_RS14090 121f37c5e8f8d0d635d8a2959726a8a8 372 SUPERFAMILY SSF103025 4 285 4.24E-91 T 13-09-2016 THL1_RS14090 121f37c5e8f8d0d635d8a2959726a8a8 372 Gene3D G3DSA:3.30.70.1400 57 140 2.9E-32 T 13-09-2016 THL1_RS14090 121f37c5e8f8d0d635d8a2959726a8a8 372 SUPERFAMILY SSF101790 278 371 4.41E-26 T 13-09-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain THL1_RS14090 121f37c5e8f8d0d635d8a2959726a8a8 372 Gene3D G3DSA:2.40.30.110 284 361 1.5E-25 T 13-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS14090 121f37c5e8f8d0d635d8a2959726a8a8 372 Pfam PF01571 Aminomethyltransferase folate-binding domain 9 256 1.4E-90 T 13-09-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal THL1_RS14090 121f37c5e8f8d0d635d8a2959726a8a8 372 PANTHER PTHR13847 4 371 3.4E-202 T 13-09-2016 THL1_RS14090 121f37c5e8f8d0d635d8a2959726a8a8 372 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 5 366 1.9E-105 T 13-09-2016 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS14090 121f37c5e8f8d0d635d8a2959726a8a8 372 PIRSF PIRSF006487 1 372 2.9E-81 T 13-09-2016 IPR028896 Aminomethyltransferase/Dimethylsulfonioproprionate demethylase DmdA KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS14090 121f37c5e8f8d0d635d8a2959726a8a8 372 PANTHER PTHR13847:SF209 4 371 3.4E-202 T 13-09-2016 THL1_RS14090 121f37c5e8f8d0d635d8a2959726a8a8 372 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 269 361 3.1E-20 T 13-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS14090 121f37c5e8f8d0d635d8a2959726a8a8 372 Gene3D G3DSA:3.30.1360.120 4 56 7.9E-58 T 13-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THL1_RS14090 121f37c5e8f8d0d635d8a2959726a8a8 372 Gene3D G3DSA:3.30.1360.120 146 233 7.9E-58 T 13-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THL1_RS15845 a5455a12a2a3fc575d63a31d950e5862 389 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 312 388 3.0E-28 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS15845 a5455a12a2a3fc575d63a31d950e5862 389 PANTHER PTHR32089 318 388 2.7E-31 T 13-09-2016 THL1_RS15845 a5455a12a2a3fc575d63a31d950e5862 389 SUPERFAMILY SSF58104 305 387 7.19E-35 T 13-09-2016 THL1_RS15845 a5455a12a2a3fc575d63a31d950e5862 389 SMART SM00086 261 303 1.0E-5 T 13-09-2016 IPR001610 PAC motif THL1_RS15845 a5455a12a2a3fc575d63a31d950e5862 389 SMART SM00086 122 164 9.3E-4 T 13-09-2016 IPR001610 PAC motif THL1_RS15845 a5455a12a2a3fc575d63a31d950e5862 389 Gene3D G3DSA:1.10.287.950 312 388 1.6E-31 T 13-09-2016 THL1_RS15845 a5455a12a2a3fc575d63a31d950e5862 389 SUPERFAMILY SSF55785 203 301 3.49E-15 T 13-09-2016 IPR000014 PAS domain THL1_RS15845 a5455a12a2a3fc575d63a31d950e5862 389 Gene3D G3DSA:3.30.450.20 176 300 2.8E-21 T 13-09-2016 THL1_RS15845 a5455a12a2a3fc575d63a31d950e5862 389 Gene3D G3DSA:3.30.450.20 28 160 4.9E-22 T 13-09-2016 THL1_RS15845 a5455a12a2a3fc575d63a31d950e5862 389 Pfam PF08447 PAS fold 67 156 9.9E-16 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS15845 a5455a12a2a3fc575d63a31d950e5862 389 Pfam PF08447 PAS fold 206 296 1.7E-20 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS15845 a5455a12a2a3fc575d63a31d950e5862 389 SUPERFAMILY SSF55785 45 165 8.72E-14 T 13-09-2016 IPR000014 PAS domain THL1_RS15845 a5455a12a2a3fc575d63a31d950e5862 389 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 38 168 2.6E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS15845 a5455a12a2a3fc575d63a31d950e5862 389 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 208 308 2.7E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS27105 77ebf8b2c93cd4edf849f50fb889b44d 514 PANTHER PTHR30031:SF0 6 514 7.2E-274 T 13-09-2016 THL1_RS27105 77ebf8b2c93cd4edf849f50fb889b44d 514 PIRSF PIRSF006294 1 514 4.5E-211 T 13-09-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 THL1_RS27105 77ebf8b2c93cd4edf849f50fb889b44d 514 Gene3D G3DSA:3.40.449.10 8 198 1.9E-69 T 13-09-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 THL1_RS27105 77ebf8b2c93cd4edf849f50fb889b44d 514 PANTHER PTHR30031 6 514 7.2E-274 T 13-09-2016 THL1_RS27105 77ebf8b2c93cd4edf849f50fb889b44d 514 Hamap MF_00453 Phosphoenolpyruvate carboxykinase [ATP] [pckA]. 1 514 52.315 T 13-09-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 THL1_RS27105 77ebf8b2c93cd4edf849f50fb889b44d 514 SUPERFAMILY SSF68923 5 199 2.96E-72 T 13-09-2016 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 THL1_RS27105 77ebf8b2c93cd4edf849f50fb889b44d 514 Gene3D G3DSA:3.90.228.20 200 262 3.1E-106 T 13-09-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 THL1_RS27105 77ebf8b2c93cd4edf849f50fb889b44d 514 Gene3D G3DSA:3.90.228.20 323 513 3.1E-106 T 13-09-2016 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: REACT_474|UniPathway: UPA00138 THL1_RS27105 77ebf8b2c93cd4edf849f50fb889b44d 514 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 7 513 2.8E-185 T 13-09-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 THL1_RS27105 77ebf8b2c93cd4edf849f50fb889b44d 514 Pfam PF01293 Phosphoenolpyruvate carboxykinase 7 468 3.5E-192 T 13-09-2016 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117|UniPathway: UPA00138 THL1_RS27105 77ebf8b2c93cd4edf849f50fb889b44d 514 SUPERFAMILY SSF53795 200 514 8.7E-129 T 13-09-2016 THL1_RS22080 12174bd97af981741bcfab6535fc3562 215 PIRSF PIRSF000370 3 215 1.4E-68 T 13-09-2016 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703|UniPathway: UPA00391 THL1_RS22080 12174bd97af981741bcfab6535fc3562 215 Pfam PF13394 4Fe-4S single cluster domain 26 109 2.1E-12 T 13-09-2016 THL1_RS22080 12174bd97af981741bcfab6535fc3562 215 Gene3D G3DSA:3.20.20.70 31 107 1.9E-14 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS22080 12174bd97af981741bcfab6535fc3562 215 PANTHER PTHR11228:SF6 1 209 7.2E-72 T 13-09-2016 THL1_RS22080 12174bd97af981741bcfab6535fc3562 215 PANTHER PTHR11228 1 209 7.2E-72 T 13-09-2016 THL1_RS22080 12174bd97af981741bcfab6535fc3562 215 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 5 212 35.886 T 13-09-2016 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703|UniPathway: UPA00391 THL1_RS22080 12174bd97af981741bcfab6535fc3562 215 Pfam PF04055 Radical SAM superfamily 28 115 1.8E-15 T 13-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 THL1_RS22080 12174bd97af981741bcfab6535fc3562 215 SUPERFAMILY SSF102114 27 105 1.44E-15 T 13-09-2016 THL1_RS22080 12174bd97af981741bcfab6535fc3562 215 TIGRFAM TIGR04349 rSAM_QueE_gams: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 5 215 8.5E-112 T 13-09-2016 IPR027621 Putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE THL1_RS25725 4b7dbd6e5bb9be04ac4249c018bf9133 195 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 5 179 2.2E-64 T 13-09-2016 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG THL1_RS25725 4b7dbd6e5bb9be04ac4249c018bf9133 195 PANTHER PTHR31223 3 194 2.6E-91 T 13-09-2016 THL1_RS25725 4b7dbd6e5bb9be04ac4249c018bf9133 195 PANTHER PTHR31223:SF0 3 194 2.6E-91 T 13-09-2016 THL1_RS25725 4b7dbd6e5bb9be04ac4249c018bf9133 195 Pfam PF03641 Possible lysine decarboxylase 48 177 8.4E-42 T 13-09-2016 IPR031100 LOG family THL1_RS25725 4b7dbd6e5bb9be04ac4249c018bf9133 195 Gene3D G3DSA:3.40.50.450 4 186 2.7E-70 T 13-09-2016 THL1_RS25725 4b7dbd6e5bb9be04ac4249c018bf9133 195 SUPERFAMILY SSF102405 3 180 3.51E-63 T 13-09-2016 THL1_RS25770 ddde94604fb3b9ff7e828e3ffd4c5018 629 PANTHER PTHR10799 254 393 6.2E-38 T 13-09-2016 THL1_RS25770 ddde94604fb3b9ff7e828e3ffd4c5018 629 SMART SM00267 433 605 3.7E-63 T 13-09-2016 IPR000160 GGDEF domain THL1_RS25770 ddde94604fb3b9ff7e828e3ffd4c5018 629 SUPERFAMILY SSF55073 449 607 1.49E-49 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS25770 ddde94604fb3b9ff7e828e3ffd4c5018 629 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 440 604 8.9E-50 T 13-09-2016 IPR000160 GGDEF domain THL1_RS25770 ddde94604fb3b9ff7e828e3ffd4c5018 629 PANTHER PTHR10799 477 599 6.2E-38 T 13-09-2016 THL1_RS25770 ddde94604fb3b9ff7e828e3ffd4c5018 629 Pfam PF00990 Diguanylate cyclase, GGDEF domain 444 599 2.3E-50 T 13-09-2016 IPR000160 GGDEF domain THL1_RS25770 ddde94604fb3b9ff7e828e3ffd4c5018 629 Pfam PF07696 7TMR-DISM extracellular 2 32 167 8.0E-23 T 13-09-2016 IPR011622 7TM-DISM receptor, extracellular domain, type 2 THL1_RS25770 ddde94604fb3b9ff7e828e3ffd4c5018 629 PANTHER PTHR10799:SF774 254 393 6.2E-38 T 13-09-2016 THL1_RS25770 ddde94604fb3b9ff7e828e3ffd4c5018 629 PANTHER PTHR10799:SF774 477 599 6.2E-38 T 13-09-2016 THL1_RS25770 ddde94604fb3b9ff7e828e3ffd4c5018 629 Gene3D G3DSA:3.30.70.270 445 607 7.8E-58 T 13-09-2016 THL1_RS25770 ddde94604fb3b9ff7e828e3ffd4c5018 629 Pfam PF07695 7TM diverse intracellular signalling 178 382 5.1E-42 T 13-09-2016 IPR011623 7TM-DISM receptor, extracellular domain, type 1 THL1_RS25095 b4debe50a57898b1a40c8587d0a6d784 65 Pfam PF00403 Heavy-metal-associated domain 3 61 1.5E-12 T 13-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THL1_RS25095 b4debe50a57898b1a40c8587d0a6d784 65 ProSitePatterns PS01047 Heavy-metal-associated domain. 6 35 - T 13-09-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 THL1_RS25095 b4debe50a57898b1a40c8587d0a6d784 65 SUPERFAMILY SSF55008 2 63 3.01E-16 T 13-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THL1_RS25095 b4debe50a57898b1a40c8587d0a6d784 65 Gene3D G3DSA:3.30.70.100 2 63 9.0E-21 T 13-09-2016 THL1_RS12115 40b07c66e27b07660bbd95fc330da56f 366 SMART SM00702 166 345 4.2E-4 T 13-09-2016 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 THL1_RS12115 40b07c66e27b07660bbd95fc330da56f 366 Gene3D G3DSA:3.40.30.10 5 152 2.7E-11 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS12115 40b07c66e27b07660bbd95fc330da56f 366 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 258 341 5.8E-11 T 13-09-2016 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 THL1_RS12115 40b07c66e27b07660bbd95fc330da56f 366 Pfam PF00578 AhpC/TSA family 11 127 6.9E-8 T 13-09-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS12115 40b07c66e27b07660bbd95fc330da56f 366 SUPERFAMILY SSF52833 7 152 4.13E-12 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS03590 45cc25afae1885c0704b6cd36a9b7131 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 2.6E-24 T 13-09-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03590 45cc25afae1885c0704b6cd36a9b7131 101 SUPERFAMILY SSF57716 2 101 1.07E-36 T 13-09-2016 THL1_RS03590 45cc25afae1885c0704b6cd36a9b7131 101 PANTHER PTHR19836 1 101 2.7E-57 T 13-09-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03590 45cc25afae1885c0704b6cd36a9b7131 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.147 T 13-09-2016 IPR023036 Ribosomal protein S14, bacterial/plastid THL1_RS03590 45cc25afae1885c0704b6cd36a9b7131 101 Gene3D G3DSA:4.10.830.10 41 101 4.3E-29 T 13-09-2016 THL1_RS24035 0d6becd96a45aae8eeeaf43ed2aa4e21 96 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 1 77 4.5E-33 T 13-09-2016 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 THL1_RS24035 0d6becd96a45aae8eeeaf43ed2aa4e21 96 PANTHER PTHR36924:SF1 1 88 1.9E-39 T 13-09-2016 THL1_RS24035 0d6becd96a45aae8eeeaf43ed2aa4e21 96 SUPERFAMILY SSF47413 5 85 3.66E-24 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS24035 0d6becd96a45aae8eeeaf43ed2aa4e21 96 SMART SM00530 9 65 6.8E-5 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS24035 0d6becd96a45aae8eeeaf43ed2aa4e21 96 PANTHER PTHR36924 1 88 1.9E-39 T 13-09-2016 THL1_RS24035 0d6becd96a45aae8eeeaf43ed2aa4e21 96 Gene3D G3DSA:1.10.260.40 2 89 4.7E-32 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS24035 0d6becd96a45aae8eeeaf43ed2aa4e21 96 Pfam PF01381 Helix-turn-helix 13 64 8.1E-7 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS28220 1e5a5207bc4c36ad1d4cce4af0f93c59 252 SUPERFAMILY SSF53850 7 250 2.05E-53 T 13-09-2016 THL1_RS28220 1e5a5207bc4c36ad1d4cce4af0f93c59 252 Gene3D G3DSA:3.40.190.10 26 106 2.1E-31 T 13-09-2016 THL1_RS28220 1e5a5207bc4c36ad1d4cce4af0f93c59 252 Gene3D G3DSA:3.40.190.10 212 249 2.1E-31 T 13-09-2016 THL1_RS28220 1e5a5207bc4c36ad1d4cce4af0f93c59 252 Gene3D G3DSA:3.40.190.10 107 205 2.9E-17 T 13-09-2016 THL1_RS28220 1e5a5207bc4c36ad1d4cce4af0f93c59 252 SMART SM00062 28 252 7.2E-46 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS28220 1e5a5207bc4c36ad1d4cce4af0f93c59 252 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 30 249 1.6E-51 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS28220 1e5a5207bc4c36ad1d4cce4af0f93c59 252 PANTHER PTHR18966:SF152 24 249 1.6E-28 T 13-09-2016 THL1_RS28220 1e5a5207bc4c36ad1d4cce4af0f93c59 252 PANTHER PTHR18966 24 249 1.6E-28 T 13-09-2016 THL1_RS04255 16bbe9bdd639ab2e36b240120bae782c 93 Pfam PF04359 Protein of unknown function (DUF493) 10 93 9.9E-25 T 13-09-2016 IPR007454 Uncharacterised protein family UPF0250 THL1_RS04255 16bbe9bdd639ab2e36b240120bae782c 93 SUPERFAMILY SSF117991 7 93 1.31E-23 T 13-09-2016 IPR027471 YbeD-like domain THL1_RS04255 16bbe9bdd639ab2e36b240120bae782c 93 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 4 93 23.472 T 13-09-2016 IPR007454 Uncharacterised protein family UPF0250 THL1_RS04255 16bbe9bdd639ab2e36b240120bae782c 93 PANTHER PTHR38036:SF1 2 93 4.5E-35 T 13-09-2016 THL1_RS04255 16bbe9bdd639ab2e36b240120bae782c 93 Gene3D G3DSA:3.30.70.1460 8 93 3.7E-25 T 13-09-2016 IPR027471 YbeD-like domain THL1_RS04255 16bbe9bdd639ab2e36b240120bae782c 93 PANTHER PTHR38036 2 93 4.5E-35 T 13-09-2016 THL1_RS23865 bda57041d4ab33004d10bf8b9ea39702 157 Gene3D G3DSA:2.60.120.10 33 118 9.9E-8 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS23865 bda57041d4ab33004d10bf8b9ea39702 157 TIGRFAM TIGR04366 cupin_WbuC: cupin fold metalloprotein, WbuC family 7 138 1.5E-45 T 13-09-2016 IPR027565 Cupin fold metalloprotein, WbuC family THL1_RS23865 bda57041d4ab33004d10bf8b9ea39702 157 SUPERFAMILY SSF51182 35 127 3.91E-13 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS05800 564eb4fe95c90c881d110b6b6f70f26c 444 SUPERFAMILY SSF53850 39 307 3.34E-37 T 13-09-2016 THL1_RS05800 564eb4fe95c90c881d110b6b6f70f26c 444 Pfam PF16868 NMT1-like family 43 279 7.6E-22 T 13-09-2016 IPR011852 TRAP transporter solute receptor, TAXI family THL1_RS05800 564eb4fe95c90c881d110b6b6f70f26c 444 PANTHER PTHR30024:SF13 1 420 1.7E-126 T 13-09-2016 THL1_RS05800 564eb4fe95c90c881d110b6b6f70f26c 444 PANTHER PTHR30024 1 420 1.7E-126 T 13-09-2016 THL1_RS05800 564eb4fe95c90c881d110b6b6f70f26c 444 Gene3D G3DSA:3.40.190.10 255 276 1.1E-9 T 13-09-2016 THL1_RS05800 564eb4fe95c90c881d110b6b6f70f26c 444 Gene3D G3DSA:3.40.190.10 42 118 1.1E-9 T 13-09-2016 THL1_RS05800 564eb4fe95c90c881d110b6b6f70f26c 444 Gene3D G3DSA:3.40.190.10 119 254 2.4E-14 T 13-09-2016 THL1_RS09430 6426f6d022aba0019532c374085d2310 145 PANTHER PTHR34309 1 143 2.6E-71 T 13-09-2016 THL1_RS09430 6426f6d022aba0019532c374085d2310 145 SUPERFAMILY SSF143744 2 137 3.14E-34 T 13-09-2016 THL1_RS09430 6426f6d022aba0019532c374085d2310 145 Pfam PF03928 Haem-degrading 4 134 8.5E-26 T 13-09-2016 IPR005624 Haem-degrading THL1_RS09430 6426f6d022aba0019532c374085d2310 145 PANTHER PTHR34309:SF3 1 143 2.6E-71 T 13-09-2016 THL1_RS01470 da68f11ae59a6360d2044829d2b8f7dd 217 Pfam PF12710 haloacid dehalogenase-like hydrolase 4 188 1.1E-38 T 13-09-2016 THL1_RS01470 da68f11ae59a6360d2044829d2b8f7dd 217 SUPERFAMILY SSF56784 2 210 6.14E-37 T 13-09-2016 IPR023214 HAD-like domain THL1_RS01470 da68f11ae59a6360d2044829d2b8f7dd 217 Gene3D G3DSA:1.20.1440.100 15 80 1.5E-30 T 13-09-2016 THL1_RS01470 da68f11ae59a6360d2044829d2b8f7dd 217 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 3 202 2.6E-43 T 13-09-2016 IPR006385 HAD-superfamily hydrolase, subfamily IB, PSPase-like, bacterial THL1_RS01470 da68f11ae59a6360d2044829d2b8f7dd 217 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 3 189 7.7E-28 T 13-09-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 THL1_RS01470 da68f11ae59a6360d2044829d2b8f7dd 217 Gene3D G3DSA:3.40.50.1000 81 216 8.1E-54 T 13-09-2016 IPR023214 HAD-like domain THL1_RS01470 da68f11ae59a6360d2044829d2b8f7dd 217 PANTHER PTHR10000:SF10 3 211 5.2E-68 T 13-09-2016 THL1_RS01470 da68f11ae59a6360d2044829d2b8f7dd 217 PANTHER PTHR10000 3 211 5.2E-68 T 13-09-2016 THL1_RS00875 48c1965a9267159f31a701079e9ed034 321 SUPERFAMILY SSF48371 65 283 1.35E-46 T 13-09-2016 IPR016024 Armadillo-type fold GO:0005488 THL1_RS00875 48c1965a9267159f31a701079e9ed034 321 PANTHER PTHR12697 14 317 4.2E-40 T 13-09-2016 THL1_RS00875 48c1965a9267159f31a701079e9ed034 321 SMART SM00567 E-Z type HEAT repeats 148 177 0.002 T 13-09-2016 IPR004155 PBS lyase HEAT-like repeat THL1_RS00875 48c1965a9267159f31a701079e9ed034 321 SMART SM00567 E-Z type HEAT repeats 23 52 18.0 T 13-09-2016 IPR004155 PBS lyase HEAT-like repeat THL1_RS00875 48c1965a9267159f31a701079e9ed034 321 SMART SM00567 E-Z type HEAT repeats 117 147 2.1 T 13-09-2016 IPR004155 PBS lyase HEAT-like repeat THL1_RS00875 48c1965a9267159f31a701079e9ed034 321 SMART SM00567 E-Z type HEAT repeats 180 209 1.7 T 13-09-2016 IPR004155 PBS lyase HEAT-like repeat THL1_RS00875 48c1965a9267159f31a701079e9ed034 321 SMART SM00567 E-Z type HEAT repeats 211 240 3.3E-6 T 13-09-2016 IPR004155 PBS lyase HEAT-like repeat THL1_RS00875 48c1965a9267159f31a701079e9ed034 321 SMART SM00567 E-Z type HEAT repeats 242 271 0.0029 T 13-09-2016 IPR004155 PBS lyase HEAT-like repeat THL1_RS00875 48c1965a9267159f31a701079e9ed034 321 SMART SM00567 E-Z type HEAT repeats 86 115 180.0 T 13-09-2016 IPR004155 PBS lyase HEAT-like repeat THL1_RS00875 48c1965a9267159f31a701079e9ed034 321 SMART SM00567 E-Z type HEAT repeats 273 302 0.4 T 13-09-2016 IPR004155 PBS lyase HEAT-like repeat THL1_RS00875 48c1965a9267159f31a701079e9ed034 321 SMART SM00567 E-Z type HEAT repeats 55 84 0.17 T 13-09-2016 IPR004155 PBS lyase HEAT-like repeat THL1_RS00875 48c1965a9267159f31a701079e9ed034 321 Gene3D G3DSA:1.25.10.10 52 318 6.5E-55 T 13-09-2016 IPR011989 Armadillo-like helical THL1_RS00875 48c1965a9267159f31a701079e9ed034 321 Pfam PF13646 HEAT repeats 14 96 2.9E-13 T 13-09-2016 THL1_RS00875 48c1965a9267159f31a701079e9ed034 321 Pfam PF13646 HEAT repeats 140 221 5.0E-16 T 13-09-2016 THL1_RS00875 48c1965a9267159f31a701079e9ed034 321 Pfam PF13646 HEAT repeats 231 315 3.4E-14 T 13-09-2016 THL1_RS00875 48c1965a9267159f31a701079e9ed034 321 SUPERFAMILY SSF48371 11 68 4.6E-6 T 13-09-2016 IPR016024 Armadillo-type fold GO:0005488 THL1_RS13765 edb41c669e4fd683c683aa2a310921b7 327 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 298 310 7.1E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS13765 edb41c669e4fd683c683aa2a310921b7 327 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 268 282 7.1E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS13765 edb41c669e4fd683c683aa2a310921b7 327 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 282 298 7.1E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS13765 edb41c669e4fd683c683aa2a310921b7 327 ProSitePatterns PS00622 LuxR-type HTH domain signature. 282 309 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS13765 edb41c669e4fd683c683aa2a310921b7 327 SMART SM00421 265 322 4.1E-18 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS13765 edb41c669e4fd683c683aa2a310921b7 327 SUPERFAMILY SSF46894 255 322 8.84E-17 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS13765 edb41c669e4fd683c683aa2a310921b7 327 Pfam PF00196 Bacterial regulatory proteins, luxR family 267 321 7.4E-15 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS13765 edb41c669e4fd683c683aa2a310921b7 327 Gene3D G3DSA:1.10.10.10 266 322 3.7E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13190 3f6a298ec44d793ae1f5d68c284104b7 452 Pfam PF07044 Protein of unknown function (DUF1329) 82 447 4.6E-156 T 13-09-2016 IPR010752 Protein of unknown function DUF1329 THL1_RS13190 3f6a298ec44d793ae1f5d68c284104b7 452 Gene3D G3DSA:2.50.20.10 158 306 1.9E-39 T 13-09-2016 THL1_RS13190 3f6a298ec44d793ae1f5d68c284104b7 452 Gene3D G3DSA:2.50.20.10 339 447 1.9E-39 T 13-09-2016 THL1_RS13495 ac8a18d7ff6202f4743a0f7ffeedede7 569 PANTHER PTHR11895 317 561 2.7E-200 T 13-09-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS13495 ac8a18d7ff6202f4743a0f7ffeedede7 569 PANTHER PTHR11895 1 296 2.7E-200 T 13-09-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS13495 ac8a18d7ff6202f4743a0f7ffeedede7 569 Gene3D G3DSA:3.90.1300.10 2 564 3.6E-118 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS13495 ac8a18d7ff6202f4743a0f7ffeedede7 569 Pfam PF01425 Amidase 25 251 3.3E-43 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS13495 ac8a18d7ff6202f4743a0f7ffeedede7 569 Pfam PF01425 Amidase 462 544 7.9E-6 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS13495 ac8a18d7ff6202f4743a0f7ffeedede7 569 PANTHER PTHR11895:SF8 317 561 2.7E-200 T 13-09-2016 THL1_RS13495 ac8a18d7ff6202f4743a0f7ffeedede7 569 PANTHER PTHR11895:SF8 1 296 2.7E-200 T 13-09-2016 THL1_RS13495 ac8a18d7ff6202f4743a0f7ffeedede7 569 SUPERFAMILY SSF75304 1 561 7.98E-89 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS26365 20c8f3ac24e7602860061861f2943a13 238 Gene3D G3DSA:3.30.70.1070 159 232 7.7E-22 T 13-09-2016 IPR007730 Sporulation-related domain GO:0042834 THL1_RS26365 20c8f3ac24e7602860061861f2943a13 238 SUPERFAMILY SSF110997 160 232 1.83E-17 T 13-09-2016 IPR007730 Sporulation-related domain GO:0042834 THL1_RS26365 20c8f3ac24e7602860061861f2943a13 238 Pfam PF05036 Sporulation related domain 162 228 3.5E-16 T 13-09-2016 IPR007730 Sporulation-related domain GO:0042834 THL1_RS14545 de9e644a300447ffb9c0430497dd622e 234 Gene3D G3DSA:3.30.559.10 6 229 4.5E-58 T 13-09-2016 IPR023213 Chloramphenicol acetyltransferase-like domain THL1_RS14545 de9e644a300447ffb9c0430497dd622e 234 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 12 230 3.1E-55 T 13-09-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 THL1_RS14545 de9e644a300447ffb9c0430497dd622e 234 PANTHER PTHR23151 7 229 9.0E-57 T 13-09-2016 THL1_RS14545 de9e644a300447ffb9c0430497dd622e 234 SUPERFAMILY SSF52777 14 230 7.12E-58 T 13-09-2016 THL1_RS24855 f9046d15caf436058e5f6e4e89fe9932 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 412 3.1E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS24855 f9046d15caf436058e5f6e4e89fe9932 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 445 3.1E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS24855 f9046d15caf436058e5f6e4e89fe9932 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 426 3.1E-10 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS24855 f9046d15caf436058e5f6e4e89fe9932 469 SUPERFAMILY SSF55874 319 463 3.14E-34 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24855 f9046d15caf436058e5f6e4e89fe9932 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 362 465 5.5E-19 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24855 f9046d15caf436058e5f6e4e89fe9932 469 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 314 4.0E-10 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24855 f9046d15caf436058e5f6e4e89fe9932 469 PANTHER PTHR24423 242 463 1.1E-46 T 13-09-2016 THL1_RS24855 f9046d15caf436058e5f6e4e89fe9932 469 PANTHER PTHR24423 83 200 1.1E-46 T 13-09-2016 THL1_RS24855 f9046d15caf436058e5f6e4e89fe9932 469 PANTHER PTHR24423 23 31 1.1E-46 T 13-09-2016 THL1_RS24855 f9046d15caf436058e5f6e4e89fe9932 469 SMART SM00388 254 318 1.7E-10 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24855 f9046d15caf436058e5f6e4e89fe9932 469 SMART SM00387 359 467 1.4E-25 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS24855 f9046d15caf436058e5f6e4e89fe9932 469 Gene3D G3DSA:1.10.287.130 250 314 1.1E-9 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24855 f9046d15caf436058e5f6e4e89fe9932 469 SUPERFAMILY SSF47384 250 315 5.69E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS24855 f9046d15caf436058e5f6e4e89fe9932 469 Gene3D G3DSA:3.30.565.10 320 463 4.7E-33 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS09335 de113041e92cfd1b7f45efddefb4af05 719 Gene3D G3DSA:3.40.50.300 483 707 5.1E-67 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09335 de113041e92cfd1b7f45efddefb4af05 719 TIGRFAM TIGR03375 type_I_sec_LssB: type I secretion system ATPase 19 712 2.0E-275 T 13-09-2016 IPR017750 ATPase, type I secretion system THL1_RS09335 de113041e92cfd1b7f45efddefb4af05 719 SUPERFAMILY SSF90123 156 466 3.01E-46 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS09335 de113041e92cfd1b7f45efddefb4af05 719 SUPERFAMILY SSF52540 474 706 9.55E-70 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09335 de113041e92cfd1b7f45efddefb4af05 719 Pfam PF00005 ABC transporter 500 649 2.3E-31 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS09335 de113041e92cfd1b7f45efddefb4af05 719 Gene3D G3DSA:3.90.70.10 16 140 7.9E-39 T 13-09-2016 THL1_RS09335 de113041e92cfd1b7f45efddefb4af05 719 PANTHER PTHR24221 40 80 1.6E-192 T 13-09-2016 THL1_RS09335 de113041e92cfd1b7f45efddefb4af05 719 PANTHER PTHR24221 139 707 1.6E-192 T 13-09-2016 THL1_RS09335 de113041e92cfd1b7f45efddefb4af05 719 Pfam PF00664 ABC transporter transmembrane region 172 431 7.2E-16 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS09335 de113041e92cfd1b7f45efddefb4af05 719 SMART SM00382 509 695 1.3E-18 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS09335 de113041e92cfd1b7f45efddefb4af05 719 PANTHER PTHR24221:SF248 40 80 1.6E-192 T 13-09-2016 THL1_RS09335 de113041e92cfd1b7f45efddefb4af05 719 Gene3D G3DSA:1.20.1560.10 156 464 1.5E-43 T 13-09-2016 THL1_RS09335 de113041e92cfd1b7f45efddefb4af05 719 PANTHER PTHR24221:SF248 139 707 1.6E-192 T 13-09-2016 THL1_RS19530 98a6a06ee29072c26919bb00383bcd42 378 SUPERFAMILY SSF160544 245 352 1.96E-40 T 13-09-2016 IPR029025 Type III secretion system substrate exporter, C-terminal THL1_RS19530 98a6a06ee29072c26919bb00383bcd42 378 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 273 288 1.6E-36 T 13-09-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THL1_RS19530 98a6a06ee29072c26919bb00383bcd42 378 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 209 227 1.6E-36 T 13-09-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THL1_RS19530 98a6a06ee29072c26919bb00383bcd42 378 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 229 246 1.6E-36 T 13-09-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THL1_RS19530 98a6a06ee29072c26919bb00383bcd42 378 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 11 33 1.6E-36 T 13-09-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THL1_RS19530 98a6a06ee29072c26919bb00383bcd42 378 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 303 324 1.6E-36 T 13-09-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THL1_RS19530 98a6a06ee29072c26919bb00383bcd42 378 Gene3D G3DSA:3.40.1690.10 219 357 1.0E-61 T 13-09-2016 IPR029025 Type III secretion system substrate exporter, C-terminal THL1_RS19530 98a6a06ee29072c26919bb00383bcd42 378 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 9 353 4.0E-124 T 13-09-2016 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 THL1_RS19530 98a6a06ee29072c26919bb00383bcd42 378 PANTHER PTHR30531 1 362 2.1E-212 T 13-09-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THL1_RS19530 98a6a06ee29072c26919bb00383bcd42 378 Pfam PF01312 FlhB HrpN YscU SpaS Family 9 348 9.9E-124 T 13-09-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THL1_RS19530 98a6a06ee29072c26919bb00383bcd42 378 PANTHER PTHR30531:SF4 1 362 2.1E-212 T 13-09-2016 THL1_RS21435 110f995f63cab6d77c886a8e29665f35 367 PANTHER PTHR11941 264 337 9.9E-91 T 13-09-2016 THL1_RS21435 110f995f63cab6d77c886a8e29665f35 367 SUPERFAMILY SSF52096 268 337 1.37E-58 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS21435 110f995f63cab6d77c886a8e29665f35 367 SUPERFAMILY SSF52096 11 201 1.37E-58 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS21435 110f995f63cab6d77c886a8e29665f35 367 PANTHER PTHR11941:SF53 15 193 9.9E-91 T 13-09-2016 THL1_RS21435 110f995f63cab6d77c886a8e29665f35 367 PANTHER PTHR11941 15 193 9.9E-91 T 13-09-2016 THL1_RS21435 110f995f63cab6d77c886a8e29665f35 367 PANTHER PTHR11941:SF53 264 337 9.9E-91 T 13-09-2016 THL1_RS21435 110f995f63cab6d77c886a8e29665f35 367 Gene3D G3DSA:3.90.226.10 269 338 1.3E-47 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS21435 110f995f63cab6d77c886a8e29665f35 367 Gene3D G3DSA:3.90.226.10 15 207 1.3E-47 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS21435 110f995f63cab6d77c886a8e29665f35 367 Pfam PF16113 Enoyl-CoA hydratase/isomerase 17 354 2.2E-106 T 13-09-2016 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 THL1_RS23265 55c2173972dc7d3dc9772f71cd26cb81 261 PANTHER PTHR32145 1 256 1.1E-87 T 13-09-2016 THL1_RS23265 55c2173972dc7d3dc9772f71cd26cb81 261 SMART SM00849 29 225 2.1E-16 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS23265 55c2173972dc7d3dc9772f71cd26cb81 261 PANTHER PTHR32145:SF7 1 256 1.1E-87 T 13-09-2016 THL1_RS23265 55c2173972dc7d3dc9772f71cd26cb81 261 SUPERFAMILY SSF56281 11 243 3.67E-29 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS23265 55c2173972dc7d3dc9772f71cd26cb81 261 Gene3D G3DSA:3.60.15.10 6 246 6.5E-49 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS23265 55c2173972dc7d3dc9772f71cd26cb81 261 Pfam PF00753 Metallo-beta-lactamase superfamily 26 225 3.9E-22 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS05845 19e45115b8862c89f2dc995e00f2d2fb 138 PANTHER PTHR38767 1 132 6.1E-33 T 13-09-2016 THL1_RS05845 19e45115b8862c89f2dc995e00f2d2fb 138 SUPERFAMILY SSF102400 2 136 3.14E-37 T 13-09-2016 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 THL1_RS05845 19e45115b8862c89f2dc995e00f2d2fb 138 Pfam PF04364 DNA polymerase III chi subunit, HolC 2 133 1.0E-36 T 13-09-2016 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 THL1_RS05845 19e45115b8862c89f2dc995e00f2d2fb 138 Gene3D G3DSA:3.40.50.10110 2 136 6.5E-42 T 13-09-2016 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 THL1_RS25515 d95689d24e6dc88f80d3c775400e0a2a 89 PANTHER PTHR38031:SF1 1 89 1.5E-12 T 13-09-2016 THL1_RS25515 d95689d24e6dc88f80d3c775400e0a2a 89 SUPERFAMILY SSF54285 6 89 1.7E-11 T 13-09-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp THL1_RS25515 d95689d24e6dc88f80d3c775400e0a2a 89 PANTHER PTHR38031 1 89 1.5E-12 T 13-09-2016 THL1_RS25515 d95689d24e6dc88f80d3c775400e0a2a 89 Gene3D G3DSA:3.10.20.30 4 86 2.2E-14 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS25570 9ec6055b3747e242ab4b883394b90582 166 SUPERFAMILY SSF55729 4 165 9.57E-35 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS25570 9ec6055b3747e242ab4b883394b90582 166 Pfam PF13420 Acetyltransferase (GNAT) domain 5 157 1.4E-20 T 13-09-2016 THL1_RS25570 9ec6055b3747e242ab4b883394b90582 166 PANTHER PTHR23091:SF187 1 166 3.5E-84 T 13-09-2016 THL1_RS25570 9ec6055b3747e242ab4b883394b90582 166 PANTHER PTHR23091 1 166 3.5E-84 T 13-09-2016 THL1_RS25570 9ec6055b3747e242ab4b883394b90582 166 Gene3D G3DSA:3.40.630.30 1 165 5.8E-42 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS23935 a43d55ba0d617ab4432e3cfd0f61b71f 415 SUPERFAMILY SSF51905 380 408 2.88E-55 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23935 a43d55ba0d617ab4432e3cfd0f61b71f 415 SUPERFAMILY SSF51905 1 300 2.88E-55 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23935 a43d55ba0d617ab4432e3cfd0f61b71f 415 Gene3D G3DSA:3.50.50.60 201 300 5.7E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23935 a43d55ba0d617ab4432e3cfd0f61b71f 415 Gene3D G3DSA:3.50.50.60 2 110 5.7E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23935 a43d55ba0d617ab4432e3cfd0f61b71f 415 Pfam PF01593 Flavin containing amine oxidoreductase 10 298 5.5E-21 T 13-09-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 THL1_RS23935 a43d55ba0d617ab4432e3cfd0f61b71f 415 PANTHER PTHR10742 1 407 1.0E-195 T 13-09-2016 THL1_RS23935 a43d55ba0d617ab4432e3cfd0f61b71f 415 PANTHER PTHR10742:SF275 1 407 1.0E-195 T 13-09-2016 THL1_RS02385 436aeafed9fdedd260d3ac50c556018f 612 Pfam PF07731 Multicopper oxidase 480 597 1.9E-15 T 13-09-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 THL1_RS02385 436aeafed9fdedd260d3ac50c556018f 612 Gene3D G3DSA:2.60.40.420 288 409 3.5E-22 T 13-09-2016 IPR008972 Cupredoxin THL1_RS02385 436aeafed9fdedd260d3ac50c556018f 612 PANTHER PTHR11709:SF2 243 602 2.4E-49 T 13-09-2016 THL1_RS02385 436aeafed9fdedd260d3ac50c556018f 612 PANTHER PTHR11709:SF2 123 227 2.4E-49 T 13-09-2016 THL1_RS02385 436aeafed9fdedd260d3ac50c556018f 612 Gene3D G3DSA:2.60.40.420 117 270 1.4E-10 T 13-09-2016 IPR008972 Cupredoxin THL1_RS02385 436aeafed9fdedd260d3ac50c556018f 612 SUPERFAMILY SSF49503 118 275 4.63E-9 T 13-09-2016 IPR008972 Cupredoxin THL1_RS02385 436aeafed9fdedd260d3ac50c556018f 612 Gene3D G3DSA:2.60.40.420 470 599 1.8E-23 T 13-09-2016 IPR008972 Cupredoxin THL1_RS02385 436aeafed9fdedd260d3ac50c556018f 612 SUPERFAMILY SSF49503 463 594 1.5E-18 T 13-09-2016 IPR008972 Cupredoxin THL1_RS02385 436aeafed9fdedd260d3ac50c556018f 612 SUPERFAMILY SSF49503 290 413 2.75E-16 T 13-09-2016 IPR008972 Cupredoxin THL1_RS02385 436aeafed9fdedd260d3ac50c556018f 612 PANTHER PTHR11709 243 602 2.4E-49 T 13-09-2016 THL1_RS02385 436aeafed9fdedd260d3ac50c556018f 612 PANTHER PTHR11709 123 227 2.4E-49 T 13-09-2016 THL1_RS03110 6fbb435daee5530497cd2ff60392c0f2 127 Pfam PF04892 VanZ like family 39 104 2.5E-9 T 13-09-2016 IPR006976 VanZ-like THL1_RS03235 4f95d90105498a12bd84c7f9a08626ed 69 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 65 16.803 T 13-09-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 THL1_RS03235 4f95d90105498a12bd84c7f9a08626ed 69 Pfam PF02416 mttA/Hcf106 family 6 42 7.8E-9 T 13-09-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 THL1_RS01595 b555cffc963956c9ab8f352437db5e32 253 SUPERFAMILY SSF53850 21 243 1.55E-40 T 13-09-2016 THL1_RS01595 b555cffc963956c9ab8f352437db5e32 253 SMART SM00062 23 246 1.6E-4 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS01595 b555cffc963956c9ab8f352437db5e32 253 Gene3D G3DSA:3.40.190.10 203 242 2.5E-15 T 13-09-2016 THL1_RS01595 b555cffc963956c9ab8f352437db5e32 253 Gene3D G3DSA:3.40.190.10 24 97 2.5E-15 T 13-09-2016 THL1_RS01595 b555cffc963956c9ab8f352437db5e32 253 PANTHER PTHR35936:SF4 4 253 8.4E-37 T 13-09-2016 THL1_RS01595 b555cffc963956c9ab8f352437db5e32 253 Gene3D G3DSA:3.40.190.10 98 188 1.8E-4 T 13-09-2016 THL1_RS01595 b555cffc963956c9ab8f352437db5e32 253 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 26 242 1.9E-25 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS01595 b555cffc963956c9ab8f352437db5e32 253 PANTHER PTHR35936 4 253 8.4E-37 T 13-09-2016 THL1_RS28210 97f2c4debb5ecfaf5cacb72247c1a1de 247 PANTHER PTHR24220:SF550 3 244 7.6E-138 T 13-09-2016 THL1_RS28210 97f2c4debb5ecfaf5cacb72247c1a1de 247 Pfam PF00005 ABC transporter 17 165 2.1E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS28210 97f2c4debb5ecfaf5cacb72247c1a1de 247 SMART SM00382 26 213 6.6E-17 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS28210 97f2c4debb5ecfaf5cacb72247c1a1de 247 Gene3D G3DSA:3.40.50.300 1 237 1.3E-83 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28210 97f2c4debb5ecfaf5cacb72247c1a1de 247 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS28210 97f2c4debb5ecfaf5cacb72247c1a1de 247 PANTHER PTHR24220 3 244 7.6E-138 T 13-09-2016 THL1_RS28210 97f2c4debb5ecfaf5cacb72247c1a1de 247 SUPERFAMILY SSF52540 1 235 1.09E-78 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28210 97f2c4debb5ecfaf5cacb72247c1a1de 247 PIRSF PIRSF039085 1 241 2.5E-116 T 13-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 SUPERFAMILY SSF52540 204 373 1.33E-42 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 SUPERFAMILY SSF52540 73 170 1.33E-42 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 12 455 3.5E-103 T 13-09-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 SUPERFAMILY SSF116878 380 455 1.31E-49 T 13-09-2016 THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 SUPERFAMILY SSF116878 121 220 1.31E-49 T 13-09-2016 THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 216 341 3.1E-20 T 13-09-2016 IPR005225 Small GTP-binding protein domain GO:0005525 THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 Gene3D G3DSA:3.40.50.300 212 246 7.6E-8 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 Pfam PF01926 50S ribosome-binding GTPase 218 308 3.9E-24 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 Gene3D G3DSA:1.20.120.430 385 455 3.3E-58 T 13-09-2016 IPR027368 tRNA modification GTPase MnmE domain 2 THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 Gene3D G3DSA:1.20.120.430 122 182 3.3E-58 T 13-09-2016 IPR027368 tRNA modification GTPase MnmE domain 2 THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 Gene3D G3DSA:1.20.120.430 247 271 3.3E-58 T 13-09-2016 IPR027368 tRNA modification GTPase MnmE domain 2 THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 PANTHER PTHR11649:SF56 9 455 1.9E-166 T 13-09-2016 THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 PANTHER PTHR11649 9 455 1.9E-166 T 13-09-2016 THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 Pfam PF10396 GTP-binding protein TrmE N-terminus 7 120 2.9E-36 T 13-09-2016 IPR018948 GTP-binding protein TrmE, N-terminal THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 Gene3D G3DSA:3.40.50.300 286 377 2.5E-7 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 286 304 2.1E-5 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 219 239 2.1E-5 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 Pfam PF12631 MnmE helical domain 123 452 1.6E-57 T 13-09-2016 IPR025867 MnmE, helical domain THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 6 455 33.121 T 13-09-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 THL1_RS28480 a402f2adf2522e9a05c71d03966ccfdd 455 Gene3D G3DSA:3.30.1360.120 5 121 1.0E-42 T 13-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THL1_RS10310 66bfeda0ae5c5ae8a1f59998fa9d053d 339 Pfam PF00092 von Willebrand factor type A domain 92 280 3.4E-31 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS10310 66bfeda0ae5c5ae8a1f59998fa9d053d 339 SMART SM00327 89 284 6.0E-22 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS10310 66bfeda0ae5c5ae8a1f59998fa9d053d 339 SUPERFAMILY SSF53300 86 267 5.04E-39 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS10310 66bfeda0ae5c5ae8a1f59998fa9d053d 339 Gene3D G3DSA:3.40.50.410 88 282 7.6E-29 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS10310 66bfeda0ae5c5ae8a1f59998fa9d053d 339 PANTHER PTHR22550 1 324 5.2E-142 T 13-09-2016 THL1_RS10310 66bfeda0ae5c5ae8a1f59998fa9d053d 339 PANTHER PTHR22550:SF12 1 324 5.2E-142 T 13-09-2016 THL1_RS16845 5ac698289682e1aae553b508786d7a78 262 ProSitePatterns PS00622 LuxR-type HTH domain signature. 215 242 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS16845 5ac698289682e1aae553b508786d7a78 262 PANTHER PTHR26402 201 259 4.5E-17 T 13-09-2016 THL1_RS16845 5ac698289682e1aae553b508786d7a78 262 Pfam PF00196 Bacterial regulatory proteins, luxR family 200 254 1.1E-15 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS16845 5ac698289682e1aae553b508786d7a78 262 SUPERFAMILY SSF46894 198 257 1.12E-14 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS16845 5ac698289682e1aae553b508786d7a78 262 SMART SM00421 198 255 1.2E-15 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS16845 5ac698289682e1aae553b508786d7a78 262 Gene3D G3DSA:1.10.10.10 200 257 1.9E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS16845 5ac698289682e1aae553b508786d7a78 262 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 231 243 5.9E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS16845 5ac698289682e1aae553b508786d7a78 262 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 201 215 5.9E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS16845 5ac698289682e1aae553b508786d7a78 262 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 215 231 5.9E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS16845 5ac698289682e1aae553b508786d7a78 262 PANTHER PTHR26402:SF572 201 259 4.5E-17 T 13-09-2016 THL1_RS20865 e1f16c65445d41343d5d0bbac11def57 350 Gene3D G3DSA:2.40.50.100 64 92 1.2E-13 T 13-09-2016 THL1_RS20865 e1f16c65445d41343d5d0bbac11def57 350 Gene3D G3DSA:2.40.50.100 167 198 1.2E-13 T 13-09-2016 THL1_RS20865 e1f16c65445d41343d5d0bbac11def57 350 Pfam PF13437 HlyD family secretion protein 170 215 4.0E-5 T 13-09-2016 THL1_RS20865 e1f16c65445d41343d5d0bbac11def57 350 SUPERFAMILY SSF111369 50 270 1.57E-21 T 13-09-2016 THL1_RS20865 e1f16c65445d41343d5d0bbac11def57 350 PANTHER PTHR30469 1 344 3.3E-47 T 13-09-2016 THL1_RS20865 e1f16c65445d41343d5d0bbac11def57 350 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 42 346 3.8E-58 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS20865 e1f16c65445d41343d5d0bbac11def57 350 Pfam PF13533 Biotin-lipoyl like 61 106 4.9E-10 T 13-09-2016 THL1_RS13410 ddaa64b127261ccb5ce6b2412e225bc5 336 Pfam PF12833 Helix-turn-helix domain 257 331 9.1E-19 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS13410 ddaa64b127261ccb5ce6b2412e225bc5 336 Gene3D G3DSA:1.10.10.60 285 331 3.9E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13410 ddaa64b127261ccb5ce6b2412e225bc5 336 SMART SM00342 250 332 1.9E-23 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS13410 ddaa64b127261ccb5ce6b2412e225bc5 336 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 23 207 4.7E-39 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS13410 ddaa64b127261ccb5ce6b2412e225bc5 336 PANTHER PTHR11019 231 331 2.7E-27 T 13-09-2016 THL1_RS13410 ddaa64b127261ccb5ce6b2412e225bc5 336 SUPERFAMILY SSF46689 285 333 3.0E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13410 ddaa64b127261ccb5ce6b2412e225bc5 336 PANTHER PTHR11019:SF52 231 331 2.7E-27 T 13-09-2016 THL1_RS13410 ddaa64b127261ccb5ce6b2412e225bc5 336 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 301 316 4.8E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS13410 ddaa64b127261ccb5ce6b2412e225bc5 336 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 316 332 4.8E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS12625 a64ed320992b312b5762c6f1014c3a86 573 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 527 542 5.0E-7 T 13-09-2016 THL1_RS12625 a64ed320992b312b5762c6f1014c3a86 573 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 5.0E-7 T 13-09-2016 THL1_RS12625 a64ed320992b312b5762c6f1014c3a86 573 Gene3D G3DSA:3.90.700.10 350 503 2.8E-32 T 13-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain THL1_RS12625 a64ed320992b312b5762c6f1014c3a86 573 SUPERFAMILY SSF56425 344 511 2.79E-34 T 13-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain THL1_RS12625 a64ed320992b312b5762c6f1014c3a86 573 Pfam PF00890 FAD binding domain 14 552 8.8E-115 T 13-09-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain THL1_RS12625 a64ed320992b312b5762c6f1014c3a86 573 Gene3D G3DSA:3.50.50.60 214 322 1.3E-68 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12625 a64ed320992b312b5762c6f1014c3a86 573 Gene3D G3DSA:3.50.50.60 10 150 1.3E-68 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12625 a64ed320992b312b5762c6f1014c3a86 573 Gene3D G3DSA:3.50.50.60 507 569 1.3E-68 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12625 a64ed320992b312b5762c6f1014c3a86 573 PANTHER PTHR11632:SF59 11 137 3.7E-199 T 13-09-2016 THL1_RS12625 a64ed320992b312b5762c6f1014c3a86 573 PANTHER PTHR11632:SF59 492 567 3.7E-199 T 13-09-2016 THL1_RS12625 a64ed320992b312b5762c6f1014c3a86 573 PANTHER PTHR11632:SF59 207 476 3.7E-199 T 13-09-2016 THL1_RS12625 a64ed320992b312b5762c6f1014c3a86 573 PANTHER PTHR11632 11 137 3.7E-199 T 13-09-2016 THL1_RS12625 a64ed320992b312b5762c6f1014c3a86 573 PANTHER PTHR11632 492 567 3.7E-199 T 13-09-2016 THL1_RS12625 a64ed320992b312b5762c6f1014c3a86 573 PANTHER PTHR11632 207 476 3.7E-199 T 13-09-2016 THL1_RS12625 a64ed320992b312b5762c6f1014c3a86 573 SUPERFAMILY SSF51905 224 319 2.88E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12625 a64ed320992b312b5762c6f1014c3a86 573 SUPERFAMILY SSF51905 11 154 2.88E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12625 a64ed320992b312b5762c6f1014c3a86 573 SUPERFAMILY SSF51905 505 570 2.88E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS26535 9ed0c9e8d356981771003677a63a9b9d 510 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 5 508 2.7E-221 T 13-09-2016 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 THL1_RS26535 9ed0c9e8d356981771003677a63a9b9d 510 Gene3D G3DSA:1.20.200.10 198 503 7.8E-129 T 13-09-2016 THL1_RS26535 9ed0c9e8d356981771003677a63a9b9d 510 SUPERFAMILY SSF48557 4 506 1.1E-190 T 13-09-2016 IPR008948 L-Aspartase-like GO:0003824 THL1_RS26535 9ed0c9e8d356981771003677a63a9b9d 510 PANTHER PTHR10362 6 496 1.8E-253 T 13-09-2016 THL1_RS26535 9ed0c9e8d356981771003677a63a9b9d 510 Gene3D G3DSA:1.10.275.10 3 197 1.7E-73 T 13-09-2016 IPR024083 Fumarase/histidase, N-terminal THL1_RS26535 9ed0c9e8d356981771003677a63a9b9d 510 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 3 504 44.915 T 13-09-2016 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 THL1_RS26535 9ed0c9e8d356981771003677a63a9b9d 510 Pfam PF00221 Aromatic amino acid lyase 11 470 1.7E-185 T 13-09-2016 IPR001106 Aromatic amino acid lyase THL1_RS26535 9ed0c9e8d356981771003677a63a9b9d 510 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 13-09-2016 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 THL1_RS26580 f487d54da285e06aeded86bbe4f53425 199 Gene3D G3DSA:1.20.58.320 7 88 1.2E-20 T 13-09-2016 THL1_RS26580 f487d54da285e06aeded86bbe4f53425 199 PANTHER PTHR23004 15 199 6.4E-70 T 13-09-2016 THL1_RS26580 f487d54da285e06aeded86bbe4f53425 199 Gene3D G3DSA:1.25.40.10 90 199 1.5E-30 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS26580 f487d54da285e06aeded86bbe4f53425 199 Pfam PF06041 Bacterial protein of unknown function (DUF924) 8 196 8.1E-56 T 13-09-2016 IPR010323 Protein of unknown function DUF924 THL1_RS26580 f487d54da285e06aeded86bbe4f53425 199 PANTHER PTHR23004:SF7 15 199 6.4E-70 T 13-09-2016 THL1_RS26580 f487d54da285e06aeded86bbe4f53425 199 SUPERFAMILY SSF48452 3 195 7.21E-55 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS13555 16b2aabe10306f5a2f63517c0e0178e3 379 PANTHER PTHR36510:SF1 1 375 7.2E-97 T 13-09-2016 THL1_RS13555 16b2aabe10306f5a2f63517c0e0178e3 379 PANTHER PTHR36510 1 375 7.2E-97 T 13-09-2016 THL1_RS13555 16b2aabe10306f5a2f63517c0e0178e3 379 SUPERFAMILY SSF55931 9 375 4.12E-70 T 13-09-2016 THL1_RS13555 16b2aabe10306f5a2f63517c0e0178e3 379 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 10 296 1.3E-81 T 13-09-2016 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 THL1_RS13555 16b2aabe10306f5a2f63517c0e0178e3 379 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 379 65.765 T 13-09-2016 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 THL1_RS13555 16b2aabe10306f5a2f63517c0e0178e3 379 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 10 289 1.7E-41 T 13-09-2016 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 Gene3D G3DSA:3.40.50.1370 3 144 4.7E-56 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 333 5.4E-133 T 13-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 Gene3D G3DSA:3.40.50.1370 145 320 8.5E-71 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 PANTHER PTHR11405:SF44 298 336 2.5E-202 T 13-09-2016 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 PANTHER PTHR11405:SF44 1 276 2.5E-202 T 13-09-2016 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 3.7E-25 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 3.7E-25 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 267 276 3.7E-25 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 298 321 3.7E-25 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 8.9E-31 T 13-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 8.9E-31 T 13-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 229 239 8.9E-31 T 13-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 8.9E-31 T 13-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 PRINTS PR00102 Ornithine carbamoyltransferase signature 312 323 8.9E-31 T 13-09-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 SUPERFAMILY SSF53671 4 334 2.75E-99 T 13-09-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 156 331 1.6E-52 T 13-09-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 334 81.051 T 13-09-2016 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 PANTHER PTHR11405 298 336 2.5E-202 T 13-09-2016 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 PANTHER PTHR11405 1 276 2.5E-202 T 13-09-2016 THL1_RS27010 e8c6af6d82b0bf620aaf543344691093 336 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 4.9E-46 T 13-09-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 THL1_RS17285 51a593b670a7be39eb687e3558f9da17 152 Gene3D G3DSA:1.10.1220.10 5 38 4.7E-5 T 13-09-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THL1_RS17285 51a593b670a7be39eb687e3558f9da17 152 SUPERFAMILY SSF47598 3 42 6.0E-5 T 13-09-2016 IPR010985 Ribbon-helix-helix GO:0006355 THL1_RS15440 a4a57a2c6d51c54c4d2e8a7fac4e94b9 285 Gene3D G3DSA:3.40.190.10 85 185 3.4E-17 T 13-09-2016 THL1_RS15440 a4a57a2c6d51c54c4d2e8a7fac4e94b9 285 SUPERFAMILY SSF53850 89 241 2.95E-30 T 13-09-2016 THL1_RS15440 a4a57a2c6d51c54c4d2e8a7fac4e94b9 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 8.0E-24 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS15440 a4a57a2c6d51c54c4d2e8a7fac4e94b9 285 Pfam PF03466 LysR substrate binding domain 86 238 8.5E-30 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS15440 a4a57a2c6d51c54c4d2e8a7fac4e94b9 285 PANTHER PTHR30579:SF0 1 279 9.2E-101 T 13-09-2016 THL1_RS15440 a4a57a2c6d51c54c4d2e8a7fac4e94b9 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 6.0E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS15440 a4a57a2c6d51c54c4d2e8a7fac4e94b9 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 6.0E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS15440 a4a57a2c6d51c54c4d2e8a7fac4e94b9 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 6.0E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS15440 a4a57a2c6d51c54c4d2e8a7fac4e94b9 285 Gene3D G3DSA:1.10.10.10 2 84 1.4E-30 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS15440 a4a57a2c6d51c54c4d2e8a7fac4e94b9 285 SUPERFAMILY SSF46785 1 110 4.81E-28 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS15440 a4a57a2c6d51c54c4d2e8a7fac4e94b9 285 Gene3D G3DSA:3.40.190.10 186 237 7.4E-10 T 13-09-2016 THL1_RS15440 a4a57a2c6d51c54c4d2e8a7fac4e94b9 285 PANTHER PTHR30579 1 279 9.2E-101 T 13-09-2016 THL1_RS19135 ffe8d2a569a03648147c106d7ba8543d 303 PANTHER PTHR30126 2 299 8.6E-97 T 13-09-2016 THL1_RS19135 ffe8d2a569a03648147c106d7ba8543d 303 Gene3D G3DSA:3.40.190.10 92 176 6.2E-22 T 13-09-2016 THL1_RS19135 ffe8d2a569a03648147c106d7ba8543d 303 SUPERFAMILY SSF46785 4 107 1.56E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19135 ffe8d2a569a03648147c106d7ba8543d 303 Gene3D G3DSA:1.10.10.10 3 88 4.4E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19135 ffe8d2a569a03648147c106d7ba8543d 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.5E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19135 ffe8d2a569a03648147c106d7ba8543d 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.5E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19135 ffe8d2a569a03648147c106d7ba8543d 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.5E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19135 ffe8d2a569a03648147c106d7ba8543d 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 9.5E-21 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19135 ffe8d2a569a03648147c106d7ba8543d 303 PANTHER PTHR30126:SF15 2 299 8.6E-97 T 13-09-2016 THL1_RS19135 ffe8d2a569a03648147c106d7ba8543d 303 SUPERFAMILY SSF53850 89 300 1.55E-44 T 13-09-2016 THL1_RS19135 ffe8d2a569a03648147c106d7ba8543d 303 Pfam PF03466 LysR substrate binding domain 88 297 1.4E-40 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS19135 ffe8d2a569a03648147c106d7ba8543d 303 Gene3D G3DSA:3.40.190.10 177 262 1.4E-18 T 13-09-2016 THL1_RS17565 da4f5800fc77ac3bca49358c9d0c529f 100 PANTHER PTHR33175 3 95 2.9E-54 T 13-09-2016 THL1_RS17565 da4f5800fc77ac3bca49358c9d0c529f 100 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 2 98 30.539 T 13-09-2016 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355|GO:0006417 THL1_RS17565 da4f5800fc77ac3bca49358c9d0c529f 100 PRINTS PR01727 Prokaryotic integration host factor signature 43 58 3.6E-17 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS17565 da4f5800fc77ac3bca49358c9d0c529f 100 PRINTS PR01727 Prokaryotic integration host factor signature 61 74 3.6E-17 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS17565 da4f5800fc77ac3bca49358c9d0c529f 100 PRINTS PR01727 Prokaryotic integration host factor signature 77 91 3.6E-17 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS17565 da4f5800fc77ac3bca49358c9d0c529f 100 SUPERFAMILY SSF47729 4 93 3.39E-31 T 13-09-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THL1_RS17565 da4f5800fc77ac3bca49358c9d0c529f 100 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 3 97 8.9E-55 T 13-09-2016 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355|GO:0006417 THL1_RS17565 da4f5800fc77ac3bca49358c9d0c529f 100 Pfam PF00216 Bacterial DNA-binding protein 4 92 2.7E-31 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS17565 da4f5800fc77ac3bca49358c9d0c529f 100 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 49 68 - T 13-09-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 THL1_RS17565 da4f5800fc77ac3bca49358c9d0c529f 100 SMART SM00411 4 93 3.6E-41 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS17565 da4f5800fc77ac3bca49358c9d0c529f 100 PANTHER PTHR33175:SF2 3 95 2.9E-54 T 13-09-2016 THL1_RS17565 da4f5800fc77ac3bca49358c9d0c529f 100 Gene3D G3DSA:4.10.520.10 4 94 9.7E-36 T 13-09-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THL1_RS12105 66c1db09c911f02dbd2eb99193b15f0e 200 Gene3D G3DSA:2.60.120.10 124 195 3.4E-20 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS12105 66c1db09c911f02dbd2eb99193b15f0e 200 SUPERFAMILY SSF47413 25 89 5.63E-15 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS12105 66c1db09c911f02dbd2eb99193b15f0e 200 PANTHER PTHR10245:SF9 1 195 4.4E-36 T 13-09-2016 THL1_RS12105 66c1db09c911f02dbd2eb99193b15f0e 200 Pfam PF07883 Cupin domain 129 194 2.4E-8 T 13-09-2016 IPR013096 Cupin 2, conserved barrel THL1_RS12105 66c1db09c911f02dbd2eb99193b15f0e 200 PANTHER PTHR10245 1 195 4.4E-36 T 13-09-2016 THL1_RS12105 66c1db09c911f02dbd2eb99193b15f0e 200 SMART SM00530 31 86 5.9E-13 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS12105 66c1db09c911f02dbd2eb99193b15f0e 200 Gene3D G3DSA:1.10.260.40 28 123 4.3E-19 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS12105 66c1db09c911f02dbd2eb99193b15f0e 200 Pfam PF13560 Helix-turn-helix domain 32 87 2.8E-11 T 13-09-2016 THL1_RS12105 66c1db09c911f02dbd2eb99193b15f0e 200 SUPERFAMILY SSF51182 103 195 9.93E-17 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS03835 cc730a8acdb7ea28feac4cff2bd5394b 141 Pfam PF09619 Type III secretion system lipoprotein chaperone (YscW) 50 117 7.7E-5 T 13-09-2016 THL1_RS06625 8986c9e19a6244d1bf05b145428c6314 624 Pfam PF07690 Major Facilitator Superfamily 19 387 6.4E-12 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS06625 8986c9e19a6244d1bf05b145428c6314 624 PANTHER PTHR10434:SF15 346 620 2.6E-151 T 13-09-2016 THL1_RS06625 8986c9e19a6244d1bf05b145428c6314 624 Gene3D G3DSA:1.20.1250.20 227 416 2.2E-7 T 13-09-2016 THL1_RS06625 8986c9e19a6244d1bf05b145428c6314 624 SMART SM00563 457 573 1.0E-25 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS06625 8986c9e19a6244d1bf05b145428c6314 624 Gene3D G3DSA:3.40.1130.10 427 570 4.3E-16 T 13-09-2016 THL1_RS06625 8986c9e19a6244d1bf05b145428c6314 624 SUPERFAMILY SSF69593 406 622 6.02E-28 T 13-09-2016 THL1_RS06625 8986c9e19a6244d1bf05b145428c6314 624 Pfam PF01553 Acyltransferase 443 570 7.9E-24 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS06625 8986c9e19a6244d1bf05b145428c6314 624 PANTHER PTHR10434 346 620 2.6E-151 T 13-09-2016 THL1_RS06625 8986c9e19a6244d1bf05b145428c6314 624 SUPERFAMILY SSF103473 47 426 5.23E-20 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS10405 2cec668659343fe51ec8a992d9dd35a2 402 PANTHER PTHR11730:SF6 1 398 4.9E-121 T 13-09-2016 THL1_RS10405 2cec668659343fe51ec8a992d9dd35a2 402 ProSitePatterns PS01219 Ammonium transporters signature. 163 188 - T 13-09-2016 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 THL1_RS10405 2cec668659343fe51ec8a992d9dd35a2 402 Pfam PF00909 Ammonium Transporter Family 19 395 4.7E-86 T 13-09-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 THL1_RS10405 2cec668659343fe51ec8a992d9dd35a2 402 SUPERFAMILY SSF111352 13 380 1.14E-92 T 13-09-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 THL1_RS10405 2cec668659343fe51ec8a992d9dd35a2 402 PANTHER PTHR11730 1 398 4.9E-121 T 13-09-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 THL1_RS10405 2cec668659343fe51ec8a992d9dd35a2 402 Gene3D G3DSA:1.10.3430.10 11 380 1.8E-90 T 13-09-2016 IPR029020 Ammonium/urea transporter THL1_RS27430 3dbfca1336b2cf11fc86edf6207f9b41 416 Gene3D G3DSA:1.25.40.10 263 302 4.1E-10 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS27430 3dbfca1336b2cf11fc86edf6207f9b41 416 Gene3D G3DSA:1.25.40.10 334 398 4.1E-10 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS27430 3dbfca1336b2cf11fc86edf6207f9b41 416 Gene3D G3DSA:1.25.40.10 93 208 1.7E-14 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS27430 3dbfca1336b2cf11fc86edf6207f9b41 416 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 7 396 1.7E-107 T 13-09-2016 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 UniPathway: UPA00252 THL1_RS27430 3dbfca1336b2cf11fc86edf6207f9b41 416 Pfam PF13176 Tetratricopeptide repeat 341 372 0.0071 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS27430 3dbfca1336b2cf11fc86edf6207f9b41 416 Pfam PF07219 HemY protein N-terminus 30 134 5.9E-25 T 13-09-2016 IPR010817 HemY, N-terminal UniPathway: UPA00252 THL1_RS27430 3dbfca1336b2cf11fc86edf6207f9b41 416 Pfam PF13432 Tetratricopeptide repeat 161 207 0.015 T 13-09-2016 THL1_RS27430 3dbfca1336b2cf11fc86edf6207f9b41 416 SUPERFAMILY SSF48452 92 190 7.27E-18 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS27430 3dbfca1336b2cf11fc86edf6207f9b41 416 SUPERFAMILY SSF48452 273 369 7.27E-18 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS27430 3dbfca1336b2cf11fc86edf6207f9b41 416 SMART SM00028 88 121 190.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS27430 3dbfca1336b2cf11fc86edf6207f9b41 416 SMART SM00028 338 371 18.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS27430 3dbfca1336b2cf11fc86edf6207f9b41 416 SMART SM00028 122 155 6.7 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS27430 3dbfca1336b2cf11fc86edf6207f9b41 416 PANTHER PTHR23083 280 303 1.4E-13 T 13-09-2016 THL1_RS27430 3dbfca1336b2cf11fc86edf6207f9b41 416 PANTHER PTHR23083 94 197 1.4E-13 T 13-09-2016 THL1_RS27430 3dbfca1336b2cf11fc86edf6207f9b41 416 PANTHER PTHR23083 335 408 1.4E-13 T 13-09-2016 THL1_RS14625 066d6380060a12bf7bf62907169edcb2 343 Gene3D G3DSA:3.40.190.10 32 121 6.7E-41 T 13-09-2016 THL1_RS14625 066d6380060a12bf7bf62907169edcb2 343 Gene3D G3DSA:3.40.190.10 272 337 6.7E-41 T 13-09-2016 THL1_RS14625 066d6380060a12bf7bf62907169edcb2 343 SUPERFAMILY SSF53850 34 336 3.8E-82 T 13-09-2016 THL1_RS14625 066d6380060a12bf7bf62907169edcb2 343 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 45 321 7.8E-53 T 13-09-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 THL1_RS14625 066d6380060a12bf7bf62907169edcb2 343 Gene3D G3DSA:3.40.190.100 124 271 1.6E-47 T 13-09-2016 THL1_RS09645 00589e909fade46603800e22dcdece63 108 PANTHER PTHR33449 1 108 1.0E-47 T 13-09-2016 THL1_RS09645 00589e909fade46603800e22dcdece63 108 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 104 4.8E-33 T 13-09-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family THL1_RS09645 00589e909fade46603800e22dcdece63 108 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 4 97 23.548 T 13-09-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family THL1_RS09645 00589e909fade46603800e22dcdece63 108 PANTHER PTHR33449:SF1 1 108 1.0E-47 T 13-09-2016 THL1_RS09645 00589e909fade46603800e22dcdece63 108 Gene3D G3DSA:3.30.1310.10 1 108 1.2E-48 T 13-09-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family THL1_RS09645 00589e909fade46603800e22dcdece63 108 Pfam PF02575 YbaB/EbfC DNA-binding family 10 98 4.1E-34 T 13-09-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family THL1_RS09645 00589e909fade46603800e22dcdece63 108 SUPERFAMILY SSF82607 10 102 3.66E-35 T 13-09-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family THL1_RS09645 00589e909fade46603800e22dcdece63 108 PIRSF PIRSF004555 2 108 3.3E-37 T 13-09-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family THL1_RS09365 0c62d2b7aa9300df07aead4c40896d01 195 Pfam PF03695 Uncharacterised protein family (UPF0149) 9 181 5.6E-34 T 13-09-2016 IPR011978 Uncharacterised protein family UPF0149 THL1_RS09365 0c62d2b7aa9300df07aead4c40896d01 195 TIGRFAM TIGR02292 ygfB_yecA: yecA family protein 6 179 1.3E-45 T 13-09-2016 IPR011978 Uncharacterised protein family UPF0149 THL1_RS09365 0c62d2b7aa9300df07aead4c40896d01 195 SUPERFAMILY SSF101327 9 181 1.57E-21 T 13-09-2016 IPR011978 Uncharacterised protein family UPF0149 THL1_RS20105 e6a39be81dc61c4479a835a110c58841 262 PANTHER PTHR30136:SF8 9 255 1.9E-99 T 13-09-2016 THL1_RS20105 e6a39be81dc61c4479a835a110c58841 262 Pfam PF09339 IclR helix-turn-helix domain 17 66 2.5E-12 T 13-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 THL1_RS20105 e6a39be81dc61c4479a835a110c58841 262 SMART SM00346 14 104 1.7E-15 T 13-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 THL1_RS20105 e6a39be81dc61c4479a835a110c58841 262 PANTHER PTHR30136 9 255 1.9E-99 T 13-09-2016 THL1_RS20105 e6a39be81dc61c4479a835a110c58841 262 SUPERFAMILY SSF55781 81 256 6.54E-34 T 13-09-2016 IPR029016 GAF domain-like THL1_RS20105 e6a39be81dc61c4479a835a110c58841 262 Pfam PF01614 Bacterial transcriptional regulator 132 251 6.5E-11 T 13-09-2016 IPR014757 Transcription regulator IclR, C-terminal THL1_RS20105 e6a39be81dc61c4479a835a110c58841 262 Gene3D G3DSA:1.10.10.10 8 83 8.9E-16 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20105 e6a39be81dc61c4479a835a110c58841 262 SUPERFAMILY SSF46785 14 86 1.27E-12 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20105 e6a39be81dc61c4479a835a110c58841 262 Gene3D G3DSA:3.30.450.40 84 259 5.2E-38 T 13-09-2016 IPR029016 GAF domain-like THL1_RS19255 b3fee1bae0c7552dfd61b0f4b4810984 209 PANTHER PTHR17490:SF7 2 205 2.3E-97 T 13-09-2016 THL1_RS19255 b3fee1bae0c7552dfd61b0f4b4810984 209 PANTHER PTHR17490 2 205 2.3E-97 T 13-09-2016 THL1_RS19255 b3fee1bae0c7552dfd61b0f4b4810984 209 Pfam PF01300 Telomere recombination 22 198 4.8E-46 T 13-09-2016 IPR006070 YrdC-like domain GO:0003725 THL1_RS19255 b3fee1bae0c7552dfd61b0f4b4810984 209 Gene3D G3DSA:3.90.870.10 3 202 9.5E-64 T 13-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain THL1_RS19255 b3fee1bae0c7552dfd61b0f4b4810984 209 SUPERFAMILY SSF55821 2 204 3.66E-66 T 13-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain THL1_RS19255 b3fee1bae0c7552dfd61b0f4b4810984 209 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 4.4E-64 T 13-09-2016 IPR006070 YrdC-like domain GO:0003725 THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 SMART SM01240 7 475 0.0 T 13-09-2016 THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 SUPERFAMILY SSF51412 216 479 1.7E-128 T 13-09-2016 THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 SUPERFAMILY SSF51412 2 90 1.7E-128 T 13-09-2016 THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 SUPERFAMILY SSF54631 94 202 1.89E-26 T 13-09-2016 THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 Gene3D G3DSA:3.20.20.70 2 487 8.8E-199 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 294 306 - T 13-09-2016 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 Reactome: REACT_1698 THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 PANTHER PTHR11911 298 487 4.2E-251 T 13-09-2016 THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 PANTHER PTHR11911 1 280 4.2E-251 T 13-09-2016 THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 PIRSF PIRSF000130 1 489 1.5E-203 T 13-09-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 8 488 84.232 T 13-09-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 8 475 7.6E-165 T 13-09-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Reactome: REACT_1698 THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 SMART SM00116 157 205 0.0022 T 13-09-2016 IPR000644 CBS domain THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 SMART SM00116 96 143 3.3E-12 T 13-09-2016 IPR000644 CBS domain THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 8 456 1.6E-190 T 13-09-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 PANTHER PTHR11911:SF6 298 487 4.2E-251 T 13-09-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 PANTHER PTHR11911:SF6 1 280 4.2E-251 T 13-09-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 Pfam PF00571 CBS domain 148 200 3.7E-5 T 13-09-2016 IPR000644 CBS domain THL1_RS06050 88383a91dc39f1cc6f3a7163799ae46c 489 Pfam PF00571 CBS domain 95 139 5.9E-11 T 13-09-2016 IPR000644 CBS domain THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 Gene3D G3DSA:3.30.70.370 807 916 1.9E-68 T 13-09-2016 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 Gene3D G3DSA:3.30.70.370 652 699 1.9E-68 T 13-09-2016 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 Pfam PF00476 DNA polymerase family A 539 914 2.2E-156 T 13-09-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 Pfam PF01612 3'-5' exonuclease 315 504 8.6E-38 T 13-09-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 Gene3D G3DSA:3.40.50.1010 5 183 4.7E-67 T 13-09-2016 IPR029060 PIN domain-like THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 SMART SM00279 170 205 5.5E-13 T 13-09-2016 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 6 167 4.1E-50 T 13-09-2016 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 SUPERFAMILY SSF56672 509 916 1.45E-161 T 13-09-2016 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 SUPERFAMILY SSF47807 168 289 2.69E-28 T 13-09-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 SUPERFAMILY SSF53098 313 504 3.7E-54 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 TIGRFAM TIGR00593 pola: DNA polymerase I 6 916 3.0E-286 T 13-09-2016 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 Gene3D G3DSA:3.30.420.10 312 529 1.7E-84 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 SMART SM00474 315 504 1.3E-36 T 13-09-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 PANTHER PTHR10133 1 915 0.0 T 13-09-2016 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 SUPERFAMILY SSF88723 5 167 4.49E-52 T 13-09-2016 IPR029060 PIN domain-like THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 ProSitePatterns PS00447 DNA polymerase family A signature. 742 761 - T 13-09-2016 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 PRINTS PR00868 DNA-polymerase family A (pol I) signature 643 665 3.9E-78 T 13-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 PRINTS PR00868 DNA-polymerase family A (pol I) signature 742 767 3.9E-78 T 13-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 PRINTS PR00868 DNA-polymerase family A (pol I) signature 779 790 3.9E-78 T 13-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 PRINTS PR00868 DNA-polymerase family A (pol I) signature 688 711 3.9E-78 T 13-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 PRINTS PR00868 DNA-polymerase family A (pol I) signature 801 812 3.9E-78 T 13-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 PRINTS PR00868 DNA-polymerase family A (pol I) signature 718 731 3.9E-78 T 13-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 PRINTS PR00868 DNA-polymerase family A (pol I) signature 833 849 3.9E-78 T 13-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 PRINTS PR00868 DNA-polymerase family A (pol I) signature 863 876 3.9E-78 T 13-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 PRINTS PR00868 DNA-polymerase family A (pol I) signature 666 681 3.9E-78 T 13-09-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 SMART SM00475 4 266 5.7E-116 T 13-09-2016 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 Gene3D G3DSA:1.10.150.20 184 251 2.1E-22 T 13-09-2016 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 Gene3D G3DSA:1.20.1060.10 530 651 1.9E-35 T 13-09-2016 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 Gene3D G3DSA:1.10.150.20 700 806 9.9E-37 T 13-09-2016 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 168 270 1.6E-26 T 13-09-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 PANTHER PTHR10133:SF27 1 915 0.0 T 13-09-2016 THL1_RS00365 94aba0de1edae33b0a58e910cca4675c 916 SMART SM00482 674 880 1.4E-118 T 13-09-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS05770 c176c3ddccfe357e0c041d45a397c9ad 374 SUPERFAMILY SSF51905 309 363 2.23E-45 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS05770 c176c3ddccfe357e0c041d45a397c9ad 374 SUPERFAMILY SSF51905 4 216 2.23E-45 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS05770 c176c3ddccfe357e0c041d45a397c9ad 374 Pfam PF01266 FAD dependent oxidoreductase 5 346 1.9E-52 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS05770 c176c3ddccfe357e0c041d45a397c9ad 374 Gene3D G3DSA:3.30.9.10 216 304 2.5E-10 T 13-09-2016 THL1_RS05770 c176c3ddccfe357e0c041d45a397c9ad 374 Gene3D G3DSA:3.30.9.10 79 140 2.5E-10 T 13-09-2016 THL1_RS05770 c176c3ddccfe357e0c041d45a397c9ad 374 PANTHER PTHR13847:SF206 3 358 8.4E-58 T 13-09-2016 THL1_RS05770 c176c3ddccfe357e0c041d45a397c9ad 374 Gene3D G3DSA:3.50.50.60 309 362 6.0E-48 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS05770 c176c3ddccfe357e0c041d45a397c9ad 374 Gene3D G3DSA:3.50.50.60 141 215 6.0E-48 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS05770 c176c3ddccfe357e0c041d45a397c9ad 374 Gene3D G3DSA:3.50.50.60 3 78 6.0E-48 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS05770 c176c3ddccfe357e0c041d45a397c9ad 374 PANTHER PTHR13847 3 358 8.4E-58 T 13-09-2016 THL1_RS23460 529c280927ef71b18c5688470e98f2aa 320 Pfam PF04773 FecR protein 116 205 3.4E-13 T 13-09-2016 IPR006860 FecR protein THL1_RS23460 529c280927ef71b18c5688470e98f2aa 320 Pfam PF16220 Domain of unknown function (DUF4880) 17 58 3.8E-15 T 13-09-2016 IPR032623 FecR, N-terminal THL1_RS23460 529c280927ef71b18c5688470e98f2aa 320 PANTHER PTHR30273:SF3 9 318 1.2E-101 T 13-09-2016 THL1_RS23460 529c280927ef71b18c5688470e98f2aa 320 PANTHER PTHR30273 9 318 1.2E-101 T 13-09-2016 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component THL1_RS23460 529c280927ef71b18c5688470e98f2aa 320 PIRSF PIRSF018266 7 317 4.8E-81 T 13-09-2016 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component THL1_RS21420 eff7ed0a32b253a75ab937b44b7fc243 497 Gene3D G3DSA:3.40.309.10 262 442 2.5E-62 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS21420 eff7ed0a32b253a75ab937b44b7fc243 497 PANTHER PTHR11699 5 496 0.0 T 13-09-2016 THL1_RS21420 eff7ed0a32b253a75ab937b44b7fc243 497 PANTHER PTHR11699:SF181 5 496 0.0 T 13-09-2016 THL1_RS21420 eff7ed0a32b253a75ab937b44b7fc243 497 Pfam PF00171 Aldehyde dehydrogenase family 13 477 8.2E-139 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS21420 eff7ed0a32b253a75ab937b44b7fc243 497 Gene3D G3DSA:3.40.605.10 4 261 1.0E-94 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS21420 eff7ed0a32b253a75ab937b44b7fc243 497 SUPERFAMILY SSF53720 3 483 2.62E-147 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS21420 eff7ed0a32b253a75ab937b44b7fc243 497 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 7 481 3.3E-237 T 13-09-2016 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373 THL1_RS04040 c913b57eb7bb61c6c69342e91f638e8f 746 PANTHER PTHR32309:SF17 1 126 1.5E-178 T 13-09-2016 THL1_RS04040 c913b57eb7bb61c6c69342e91f638e8f 746 PANTHER PTHR32309:SF17 207 746 1.5E-178 T 13-09-2016 THL1_RS04040 c913b57eb7bb61c6c69342e91f638e8f 746 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 532 736 1.9E-52 T 13-09-2016 IPR005702 Exopolysaccharide synthesis protein GO:0045226 THL1_RS04040 c913b57eb7bb61c6c69342e91f638e8f 746 PANTHER PTHR32309 207 746 1.5E-178 T 13-09-2016 THL1_RS04040 c913b57eb7bb61c6c69342e91f638e8f 746 PANTHER PTHR32309 1 126 1.5E-178 T 13-09-2016 THL1_RS04040 c913b57eb7bb61c6c69342e91f638e8f 746 Gene3D G3DSA:3.40.50.300 551 730 4.9E-33 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04040 c913b57eb7bb61c6c69342e91f638e8f 746 SUPERFAMILY SSF52540 550 731 1.0E-36 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04040 c913b57eb7bb61c6c69342e91f638e8f 746 Pfam PF13614 AAA domain 562 674 2.8E-14 T 13-09-2016 IPR025669 AAA domain THL1_RS04040 c913b57eb7bb61c6c69342e91f638e8f 746 Pfam PF02706 Chain length determinant protein 16 272 3.3E-36 T 13-09-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 THL1_RS04040 c913b57eb7bb61c6c69342e91f638e8f 746 Pfam PF13807 G-rich domain on putative tyrosine kinase 389 471 2.8E-33 T 13-09-2016 IPR032807 Tyrosine kinase, G-rich domain THL1_RS14560 ee2699dbf0afdb0985c9fc24162b3226 295 SUPERFAMILY SSF46785 6 114 7.71E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14560 ee2699dbf0afdb0985c9fc24162b3226 295 PANTHER PTHR30537:SF26 1 283 4.0E-71 T 13-09-2016 THL1_RS14560 ee2699dbf0afdb0985c9fc24162b3226 295 Pfam PF03466 LysR substrate binding domain 95 282 1.6E-26 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS14560 ee2699dbf0afdb0985c9fc24162b3226 295 Gene3D G3DSA:3.40.190.10 172 251 2.2E-11 T 13-09-2016 THL1_RS14560 ee2699dbf0afdb0985c9fc24162b3226 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.5E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14560 ee2699dbf0afdb0985c9fc24162b3226 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.5E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14560 ee2699dbf0afdb0985c9fc24162b3226 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.5E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14560 ee2699dbf0afdb0985c9fc24162b3226 295 SUPERFAMILY SSF53850 95 283 7.24E-29 T 13-09-2016 THL1_RS14560 ee2699dbf0afdb0985c9fc24162b3226 295 Gene3D G3DSA:1.10.10.10 8 91 6.9E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14560 ee2699dbf0afdb0985c9fc24162b3226 295 PANTHER PTHR30537 1 283 4.0E-71 T 13-09-2016 THL1_RS14560 ee2699dbf0afdb0985c9fc24162b3226 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 2.2E-21 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14560 ee2699dbf0afdb0985c9fc24162b3226 295 Gene3D G3DSA:3.40.190.10 95 171 2.5E-23 T 13-09-2016 THL1_RS21800 87fe3dcf35810b182846a32ccf731057 168 SMART SM00903 14 159 9.6E-38 T 13-09-2016 IPR002563 Flavin reductase like domain GO:0010181 THL1_RS21800 87fe3dcf35810b182846a32ccf731057 168 SUPERFAMILY SSF50475 12 160 4.71E-41 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS21800 87fe3dcf35810b182846a32ccf731057 168 PANTHER PTHR30466:SF2 12 157 6.9E-35 T 13-09-2016 THL1_RS21800 87fe3dcf35810b182846a32ccf731057 168 Gene3D G3DSA:2.30.110.10 6 158 1.1E-43 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS21800 87fe3dcf35810b182846a32ccf731057 168 PANTHER PTHR30466 12 157 6.9E-35 T 13-09-2016 THL1_RS21800 87fe3dcf35810b182846a32ccf731057 168 Pfam PF01613 Flavin reductase like domain 14 160 2.9E-29 T 13-09-2016 IPR002563 Flavin reductase like domain GO:0010181 THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 Gene3D G3DSA:3.40.50.1440 14 214 2.1E-91 T 13-09-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 9 328 3.7E-127 T 13-09-2016 IPR000158 Cell division protein FtsZ GO:0005525 THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 368 37.639 T 13-09-2016 IPR000158 Cell division protein FtsZ GO:0005525 THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 13-09-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 SMART SM00864 13 205 4.9E-113 T 13-09-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 PANTHER PTHR30314:SF3 1 393 1.1E-196 T 13-09-2016 THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 PRINTS PR00423 Cell division protein FtsZ signature 212 233 1.1E-50 T 13-09-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 PRINTS PR00423 Cell division protein FtsZ signature 189 211 1.1E-50 T 13-09-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 PRINTS PR00423 Cell division protein FtsZ signature 98 118 1.1E-50 T 13-09-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 PRINTS PR00423 Cell division protein FtsZ signature 126 147 1.1E-50 T 13-09-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 6.5E-40 T 13-09-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 Pfam PF12327 FtsZ family, C-terminal domain 222 316 2.3E-36 T 13-09-2016 IPR024757 Cell division protein FtsZ, C-terminal THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 Gene3D G3DSA:3.30.1330.20 215 319 1.3E-45 T 13-09-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 PANTHER PTHR30314 1 393 1.1E-196 T 13-09-2016 THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 SUPERFAMILY SSF52490 13 208 4.32E-69 T 13-09-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 SMART SM00865 207 325 1.4E-57 T 13-09-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 SUPERFAMILY SSF55307 204 319 2.13E-42 T 13-09-2016 IPR008280 Tubulin/FtsZ, C-terminal THL1_RS05665 3b594fae93cf6b083958305d2d0d7747 395 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 13-09-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 THL1_RS08345 06cd7c40f6eae480aee52df626b280f3 118 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 19 110 4.5E-29 T 13-09-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 THL1_RS08345 06cd7c40f6eae480aee52df626b280f3 118 SUPERFAMILY SSF55248 16 112 6.93E-33 T 13-09-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 THL1_RS08345 06cd7c40f6eae480aee52df626b280f3 118 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 16 111 22.345 T 13-09-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 THL1_RS08345 06cd7c40f6eae480aee52df626b280f3 118 Gene3D G3DSA:3.30.1360.20 12 112 1.3E-32 T 13-09-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 THL1_RS08345 06cd7c40f6eae480aee52df626b280f3 118 PANTHER PTHR12599 3 112 8.5E-34 T 13-09-2016 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 THL1_RS07650 703fbc66344c4f5832d42347972d0111 386 PANTHER PTHR13504:SF29 6 372 4.6E-95 T 13-09-2016 THL1_RS07650 703fbc66344c4f5832d42347972d0111 386 SUPERFAMILY SSF140931 88 273 7.85E-34 T 13-09-2016 IPR003812 Fido domain THL1_RS07650 703fbc66344c4f5832d42347972d0111 386 Gene3D G3DSA:1.10.3290.10 29 273 3.6E-50 T 13-09-2016 IPR003812 Fido domain THL1_RS07650 703fbc66344c4f5832d42347972d0111 386 Pfam PF02661 Fic/DOC family 110 210 4.1E-19 T 13-09-2016 IPR003812 Fido domain THL1_RS07650 703fbc66344c4f5832d42347972d0111 386 PANTHER PTHR13504 6 372 4.6E-95 T 13-09-2016 THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 Gene3D G3DSA:3.30.70.270 471 635 1.6E-48 T 13-09-2016 THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 PANTHER PTHR10799 449 718 2.6E-86 T 13-09-2016 THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 466 626 2.6E-35 T 13-09-2016 IPR000160 GGDEF domain THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 Gene3D G3DSA:3.20.20.450 642 888 5.9E-99 T 13-09-2016 IPR001633 EAL domain THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 SUPERFAMILY SSF55781 194 334 7.85E-21 T 13-09-2016 IPR029016 GAF domain-like THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 PANTHER PTHR10799 857 876 2.6E-86 T 13-09-2016 THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 SMART SM00091 345 411 1.1E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 SMART SM00091 14 87 50.0 T 13-09-2016 IPR000014 PAS domain THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 SMART SM00267 459 628 3.5E-54 T 13-09-2016 IPR000160 GGDEF domain THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 Pfam PF01590 GAF domain 194 330 1.3E-12 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 SUPERFAMILY SSF141868 643 890 1.28E-90 T 13-09-2016 IPR001633 EAL domain THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 Gene3D G3DSA:3.30.450.20 355 458 1.8E-20 T 13-09-2016 THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 PANTHER PTHR10799:SF710 857 876 2.6E-86 T 13-09-2016 THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 PANTHER PTHR10799:SF710 449 718 2.6E-86 T 13-09-2016 THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 SUPERFAMILY SSF55785 351 457 1.77E-21 T 13-09-2016 IPR000014 PAS domain THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 Gene3D G3DSA:3.30.450.40 168 341 1.0E-18 T 13-09-2016 IPR029016 GAF domain-like THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 SMART SM00065 192 342 5.6E-9 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 Pfam PF00990 Diguanylate cyclase, GGDEF domain 470 623 4.4E-39 T 13-09-2016 IPR000160 GGDEF domain THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 Pfam PF00563 EAL domain 644 879 1.0E-75 T 13-09-2016 IPR001633 EAL domain THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 SUPERFAMILY SSF55073 475 629 2.9E-42 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 SMART SM00086 417 459 1.1E-5 T 13-09-2016 IPR001610 PAC motif THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 SMART SM00052 638 884 4.5E-119 T 13-09-2016 IPR001633 EAL domain THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 Pfam PF13426 PAS domain 357 458 2.8E-14 T 13-09-2016 IPR000014 PAS domain THL1_RS26200 fe854c8a42432558b439fbdb4caff31d 898 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 346 465 2.6E-15 T 13-09-2016 IPR000014 PAS domain THL1_RS03755 ad7e7d4169b592697e292e3d77a2eadb 350 PANTHER PTHR13748 1 349 1.5E-159 T 13-09-2016 THL1_RS03755 ad7e7d4169b592697e292e3d77a2eadb 350 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 8 215 2.5E-59 T 13-09-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain THL1_RS03755 ad7e7d4169b592697e292e3d77a2eadb 350 TIGRFAM TIGR02475 CobW: cobalamin biosynthesis protein CobW 5 345 3.5E-171 T 13-09-2016 IPR012824 Cobalamin (vitamin B12) biosynthesis CobW GO:0009236 UniPathway: UPA00148 THL1_RS03755 ad7e7d4169b592697e292e3d77a2eadb 350 SUPERFAMILY SSF52540 6 244 3.48E-33 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03755 ad7e7d4169b592697e292e3d77a2eadb 350 Gene3D G3DSA:3.40.50.300 6 231 7.4E-64 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03755 ad7e7d4169b592697e292e3d77a2eadb 350 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 270 348 7.1E-16 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS03755 ad7e7d4169b592697e292e3d77a2eadb 350 SMART SM00833 258 349 4.2E-5 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS03755 ad7e7d4169b592697e292e3d77a2eadb 350 Gene3D G3DSA:3.30.1220.10 243 349 4.9E-29 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS03755 ad7e7d4169b592697e292e3d77a2eadb 350 SUPERFAMILY SSF90002 268 349 5.23E-19 T 13-09-2016 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THL1_RS03755 ad7e7d4169b592697e292e3d77a2eadb 350 PANTHER PTHR13748:SF10 1 349 1.5E-159 T 13-09-2016 IPR012824 Cobalamin (vitamin B12) biosynthesis CobW GO:0009236 UniPathway: UPA00148 THL1_RS05940 07f4c7843104745357e3e6b003fd858b 107 Gene3D G3DSA:2.60.300.12 2 96 1.2E-33 T 13-09-2016 IPR000361 FeS cluster biogenesis THL1_RS05940 07f4c7843104745357e3e6b003fd858b 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 7.2E-24 T 13-09-2016 IPR000361 FeS cluster biogenesis THL1_RS05940 07f4c7843104745357e3e6b003fd858b 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 3 107 1.4E-52 T 13-09-2016 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0016226|GO:0051536 THL1_RS05940 07f4c7843104745357e3e6b003fd858b 107 PANTHER PTHR10072:SF48 1 107 8.2E-50 T 13-09-2016 IPR031108 FeS assembly protein IscA-like GO:0005198|GO:0016226|GO:0051536 THL1_RS05940 07f4c7843104745357e3e6b003fd858b 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 13-09-2016 IPR017870 FeS cluster insertion, C-terminal, conserved site THL1_RS05940 07f4c7843104745357e3e6b003fd858b 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 8.2E-36 T 13-09-2016 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 THL1_RS05940 07f4c7843104745357e3e6b003fd858b 107 PANTHER PTHR10072 1 107 8.2E-50 T 13-09-2016 THL1_RS05940 07f4c7843104745357e3e6b003fd858b 107 SUPERFAMILY SSF89360 1 96 2.22E-31 T 13-09-2016 IPR000361 FeS cluster biogenesis THL1_RS10130 71d2d748dfe1467375c90edf2bb68a02 403 Gene3D G3DSA:3.90.1150.10 268 401 3.9E-53 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS10130 71d2d748dfe1467375c90edf2bb68a02 403 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 211 225 - T 13-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 THL1_RS10130 71d2d748dfe1467375c90edf2bb68a02 403 PANTHER PTHR11808:SF36 1 403 3.9E-239 T 13-09-2016 THL1_RS10130 71d2d748dfe1467375c90edf2bb68a02 403 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 20 400 9.1E-146 T 13-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 THL1_RS10130 71d2d748dfe1467375c90edf2bb68a02 403 PIRSF PIRSF001434 7 403 2.3E-139 T 13-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 THL1_RS10130 71d2d748dfe1467375c90edf2bb68a02 403 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 20 400 9.6E-198 T 13-09-2016 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 UniPathway: UPA00051 THL1_RS10130 71d2d748dfe1467375c90edf2bb68a02 403 SUPERFAMILY SSF53383 40 400 3.99E-126 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS10130 71d2d748dfe1467375c90edf2bb68a02 403 PANTHER PTHR11808 1 403 3.9E-239 T 13-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 THL1_RS10130 71d2d748dfe1467375c90edf2bb68a02 403 Gene3D G3DSA:3.40.640.10 19 267 2.8E-94 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS26710 5e0e0a07ba5d476ce06d9c2baafe47e1 511 Gene3D G3DSA:3.40.720.10 6 79 2.5E-89 T 13-09-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THL1_RS26710 5e0e0a07ba5d476ce06d9c2baafe47e1 511 Gene3D G3DSA:3.40.720.10 312 509 2.5E-89 T 13-09-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THL1_RS26710 5e0e0a07ba5d476ce06d9c2baafe47e1 511 SUPERFAMILY SSF53649 5 79 1.96E-77 T 13-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THL1_RS26710 5e0e0a07ba5d476ce06d9c2baafe47e1 511 SUPERFAMILY SSF53649 312 508 1.96E-77 T 13-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THL1_RS26710 5e0e0a07ba5d476ce06d9c2baafe47e1 511 SUPERFAMILY SSF64158 79 307 1.07E-81 T 13-09-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 THL1_RS26710 5e0e0a07ba5d476ce06d9c2baafe47e1 511 PIRSF PIRSF001492 1 511 2.6E-205 T 13-09-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 THL1_RS26710 5e0e0a07ba5d476ce06d9c2baafe47e1 511 PANTHER PTHR31637:SF0 1 511 4.3E-286 T 13-09-2016 THL1_RS26710 5e0e0a07ba5d476ce06d9c2baafe47e1 511 PANTHER PTHR31637 1 511 4.3E-286 T 13-09-2016 THL1_RS26710 5e0e0a07ba5d476ce06d9c2baafe47e1 511 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 6 508 6.7E-235 T 13-09-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 THL1_RS26710 5e0e0a07ba5d476ce06d9c2baafe47e1 511 Pfam PF01676 Metalloenzyme superfamily 6 496 1.9E-81 T 13-09-2016 IPR006124 Metalloenzyme GO:0003824|GO:0046872 THL1_RS26710 5e0e0a07ba5d476ce06d9c2baafe47e1 511 Gene3D G3DSA:3.40.1450.10 80 308 9.2E-93 T 13-09-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 THL1_RS26710 5e0e0a07ba5d476ce06d9c2baafe47e1 511 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 6 509 51.037 T 13-09-2016 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 THL1_RS26710 5e0e0a07ba5d476ce06d9c2baafe47e1 511 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 84 296 2.9E-79 T 13-09-2016 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 SMART SM00448 5 116 2.2E-32 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 Gene3D G3DSA:3.40.50.300 138 312 7.0E-61 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 SUPERFAMILY SSF52172 5 186 9.39E-44 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 PANTHER PTHR32071:SF15 1 476 3.8E-255 T 13-09-2016 THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 Pfam PF00072 Response regulator receiver domain 7 115 3.2E-29 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 429 446 2.5E-7 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 446 466 2.5E-7 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 Gene3D G3DSA:1.10.10.60 398 466 8.1E-22 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 SUPERFAMILY SSF46689 381 465 1.75E-20 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 227 242 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 Gene3D G3DSA:3.40.50.2300 6 132 7.5E-36 T 13-09-2016 THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 165 178 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 SMART SM00382 161 304 6.3E-12 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 PANTHER PTHR32071 1 476 3.8E-255 T 13-09-2016 THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 354 363 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 Pfam PF00158 Sigma-54 interaction domain 141 308 2.3E-71 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 SUPERFAMILY SSF52540 140 384 2.54E-73 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 7 463 1.5E-241 T 13-09-2016 IPR010114 Signal transduction response regulator, nitrogen regulation NR(I) GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 Pfam PF02954 Bacterial regulatory protein, Fis family 423 463 4.6E-13 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS26680 38e6523140c1792ae6aac559180c5064 478 Gene3D G3DSA:1.10.8.60 314 387 1.4E-23 T 13-09-2016 THL1_RS25530 ac7a2150ddaea14fd7b51728bc9ce9cc 238 SMART SM00345 21 79 9.3E-15 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS25530 ac7a2150ddaea14fd7b51728bc9ce9cc 238 PANTHER PTHR11751 20 105 1.9E-20 T 13-09-2016 THL1_RS25530 ac7a2150ddaea14fd7b51728bc9ce9cc 238 Pfam PF07729 FCD domain 89 212 2.3E-21 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS25530 ac7a2150ddaea14fd7b51728bc9ce9cc 238 SUPERFAMILY SSF46785 14 104 9.09E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS25530 ac7a2150ddaea14fd7b51728bc9ce9cc 238 SUPERFAMILY SSF48008 85 220 2.33E-28 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS25530 ac7a2150ddaea14fd7b51728bc9ce9cc 238 Gene3D G3DSA:1.10.10.10 6 80 1.4E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS25530 ac7a2150ddaea14fd7b51728bc9ce9cc 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 79 3.8E-17 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS25530 ac7a2150ddaea14fd7b51728bc9ce9cc 238 Gene3D G3DSA:1.20.120.530 83 221 1.5E-31 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS25530 ac7a2150ddaea14fd7b51728bc9ce9cc 238 SMART SM00895 89 213 5.5E-19 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS21335 cdcfa9e2e409ed7cd3b7e4b9de4b78a9 538 Gene3D G3DSA:1.20.58.100 418 521 5.3E-32 T 13-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 THL1_RS21335 cdcfa9e2e409ed7cd3b7e4b9de4b78a9 538 PIRSF PIRSF000171 1 532 1.5E-36 T 13-09-2016 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit THL1_RS21335 cdcfa9e2e409ed7cd3b7e4b9de4b78a9 538 Pfam PF02910 Fumarate reductase flavoprotein C-term 441 521 2.2E-13 T 13-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 THL1_RS21335 cdcfa9e2e409ed7cd3b7e4b9de4b78a9 538 Gene3D G3DSA:3.90.700.10 244 348 1.1E-40 T 13-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain THL1_RS21335 cdcfa9e2e409ed7cd3b7e4b9de4b78a9 538 SUPERFAMILY SSF51905 356 448 2.16E-74 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21335 cdcfa9e2e409ed7cd3b7e4b9de4b78a9 538 SUPERFAMILY SSF51905 4 255 2.16E-74 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21335 cdcfa9e2e409ed7cd3b7e4b9de4b78a9 538 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 355 377 3.0E-9 T 13-09-2016 THL1_RS21335 cdcfa9e2e409ed7cd3b7e4b9de4b78a9 538 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.0E-9 T 13-09-2016 THL1_RS21335 cdcfa9e2e409ed7cd3b7e4b9de4b78a9 538 Pfam PF00890 FAD binding domain 8 392 2.0E-104 T 13-09-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain THL1_RS21335 cdcfa9e2e409ed7cd3b7e4b9de4b78a9 538 SUPERFAMILY SSF46977 425 526 3.79E-31 T 13-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 THL1_RS21335 cdcfa9e2e409ed7cd3b7e4b9de4b78a9 538 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 6 520 4.9E-203 T 13-09-2016 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 THL1_RS21335 cdcfa9e2e409ed7cd3b7e4b9de4b78a9 538 Gene3D G3DSA:3.50.50.60 349 412 6.8E-102 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21335 cdcfa9e2e409ed7cd3b7e4b9de4b78a9 538 Gene3D G3DSA:3.50.50.60 4 243 6.8E-102 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21335 cdcfa9e2e409ed7cd3b7e4b9de4b78a9 538 PANTHER PTHR11632:SF27 6 533 6.7E-267 T 13-09-2016 THL1_RS21335 cdcfa9e2e409ed7cd3b7e4b9de4b78a9 538 SUPERFAMILY SSF56425 238 353 2.09E-43 T 13-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain THL1_RS21335 cdcfa9e2e409ed7cd3b7e4b9de4b78a9 538 PANTHER PTHR11632 6 533 6.7E-267 T 13-09-2016 THL1_RS06230 26e8212f58bc5b2d3791b54426273298 106 Pfam PF06052 3-hydroxyanthranilic acid dioxygenase 42 103 2.4E-4 T 13-09-2016 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|UniPathway: UPA00253 THL1_RS06230 26e8212f58bc5b2d3791b54426273298 106 Gene3D G3DSA:2.60.120.10 22 104 2.5E-11 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS06230 26e8212f58bc5b2d3791b54426273298 106 SUPERFAMILY SSF51182 39 104 1.16E-12 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS18135 d88ae76fc7031bd6690d1aa257c047e2 274 Pfam PF00924 Mechanosensitive ion channel 174 271 4.5E-9 T 13-09-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 THL1_RS18135 d88ae76fc7031bd6690d1aa257c047e2 274 SUPERFAMILY SSF50182 220 272 9.81E-7 T 13-09-2016 IPR010920 LSM domain THL1_RS18135 d88ae76fc7031bd6690d1aa257c047e2 274 PANTHER PTHR30221 1 274 1.1E-94 T 13-09-2016 THL1_RS18135 d88ae76fc7031bd6690d1aa257c047e2 274 Gene3D G3DSA:2.30.30.60 226 272 3.6E-9 T 13-09-2016 THL1_RS18135 d88ae76fc7031bd6690d1aa257c047e2 274 Pfam PF05552 Conserved TM helix 109 154 1.1E-8 T 13-09-2016 IPR008910 Conserved TM helix THL1_RS18135 d88ae76fc7031bd6690d1aa257c047e2 274 Pfam PF05552 Conserved TM helix 16 60 1.1E-10 T 13-09-2016 IPR008910 Conserved TM helix THL1_RS18135 d88ae76fc7031bd6690d1aa257c047e2 274 PANTHER PTHR30221:SF7 1 274 1.1E-94 T 13-09-2016 THL1_RS16925 dabcde16388ecf6dfc989a5cdcb4b1c6 198 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 92 1.6E-23 T 13-09-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal THL1_RS16925 dabcde16388ecf6dfc989a5cdcb4b1c6 198 PANTHER PTHR14239 1 180 2.5E-35 T 13-09-2016 THL1_RS16925 dabcde16388ecf6dfc989a5cdcb4b1c6 198 SUPERFAMILY SSF51735 1 182 8.1E-40 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS16925 dabcde16388ecf6dfc989a5cdcb4b1c6 198 Gene3D G3DSA:3.40.50.720 1 182 4.6E-49 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS08495 a1715bdcbbe787861dede88bcb0926e1 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 268 1.1E-16 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS08495 a1715bdcbbe787861dede88bcb0926e1 281 PANTHER PTHR30193:SF20 18 276 1.0E-50 T 13-09-2016 THL1_RS08495 a1715bdcbbe787861dede88bcb0926e1 281 SUPERFAMILY SSF161098 18 277 1.4E-52 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS08495 a1715bdcbbe787861dede88bcb0926e1 281 Gene3D G3DSA:1.10.3720.10 18 273 6.5E-47 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS08495 a1715bdcbbe787861dede88bcb0926e1 281 PANTHER PTHR30193 18 276 1.0E-50 T 13-09-2016 THL1_RS25020 a861d50ddb757d9ba93bcb603ce44137 110 Pfam PF02501 Type II secretion system (T2SS), protein I 28 106 5.1E-17 T 13-09-2016 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 THL1_RS25020 a861d50ddb757d9ba93bcb603ce44137 110 TIGRFAM TIGR01707 gspI: type II secretion system protein I 1 91 1.1E-18 T 13-09-2016 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 THL1_RS25020 a861d50ddb757d9ba93bcb603ce44137 110 Gene3D G3DSA:3.30.1300.30 25 106 5.8E-15 T 13-09-2016 THL1_RS25020 a861d50ddb757d9ba93bcb603ce44137 110 SUPERFAMILY SSF54523 27 106 6.83E-15 T 13-09-2016 THL1_RS25020 a861d50ddb757d9ba93bcb603ce44137 110 PANTHER PTHR38779 1 110 1.3E-12 T 13-09-2016 THL1_RS23330 c323151cf859ab0cb3f8ac1ad781c7eb 135 SUPERFAMILY SSF55021 3 66 5.95E-16 T 13-09-2016 THL1_RS23330 c323151cf859ab0cb3f8ac1ad781c7eb 135 Pfam PF10000 ACT domain 2 69 2.3E-24 T 13-09-2016 IPR018717 Domain of unknown function DUF2241 THL1_RS23330 c323151cf859ab0cb3f8ac1ad781c7eb 135 Gene3D G3DSA:3.30.2130.10 1 129 1.7E-51 T 13-09-2016 THL1_RS23330 c323151cf859ab0cb3f8ac1ad781c7eb 135 PANTHER PTHR39199 1 135 1.3E-52 T 13-09-2016 THL1_RS23330 c323151cf859ab0cb3f8ac1ad781c7eb 135 SUPERFAMILY SSF55021 70 128 5.89E-18 T 13-09-2016 THL1_RS23330 c323151cf859ab0cb3f8ac1ad781c7eb 135 PANTHER PTHR39199:SF1 1 135 1.3E-52 T 13-09-2016 THL1_RS23330 c323151cf859ab0cb3f8ac1ad781c7eb 135 Pfam PF13840 ACT domain 70 126 8.5E-13 T 13-09-2016 IPR027795 GATS-like ACT domain THL1_RS16095 004cbc511d7dd1191e7f746101966d4b 336 TIGRFAM TIGR01551 major_capsid_P2: phage major capsid protein, P2 family 8 333 1.3E-97 T 13-09-2016 IPR006441 Bacteriophage P2, GpN, major capsid GO:0019028 THL1_RS16095 004cbc511d7dd1191e7f746101966d4b 336 Pfam PF05125 Phage major capsid protein, P2 family 9 332 5.8E-140 T 13-09-2016 IPR006441 Bacteriophage P2, GpN, major capsid GO:0019028 THL1_RS28265 5c2ac3e0a122218db1d3a23334d96154 286 PANTHER PTHR41542:SF1 1 286 1.3E-79 T 13-09-2016 THL1_RS28265 5c2ac3e0a122218db1d3a23334d96154 286 SMART SM00978 154 285 2.4E-20 T 13-09-2016 IPR007379 Tim44-like domain THL1_RS28265 5c2ac3e0a122218db1d3a23334d96154 286 SUPERFAMILY SSF54427 164 284 2.54E-5 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS28265 5c2ac3e0a122218db1d3a23334d96154 286 PANTHER PTHR41542 1 286 1.3E-79 T 13-09-2016 THL1_RS26545 bf8fae4c22270598bd451b3a1f7165ce 326 Gene3D G3DSA:3.40.190.10 22 104 2.4E-13 T 13-09-2016 THL1_RS26545 bf8fae4c22270598bd451b3a1f7165ce 326 Gene3D G3DSA:3.40.190.10 257 315 2.4E-13 T 13-09-2016 THL1_RS26545 bf8fae4c22270598bd451b3a1f7165ce 326 SUPERFAMILY SSF53850 17 320 1.03E-77 T 13-09-2016 THL1_RS26545 bf8fae4c22270598bd451b3a1f7165ce 326 Gene3D G3DSA:3.40.190.100 105 256 2.4E-45 T 13-09-2016 THL1_RS26545 bf8fae4c22270598bd451b3a1f7165ce 326 PANTHER PTHR30177 22 308 2.1E-146 T 13-09-2016 THL1_RS26545 bf8fae4c22270598bd451b3a1f7165ce 326 PANTHER PTHR30177:SF14 22 308 2.1E-146 T 13-09-2016 THL1_RS26545 bf8fae4c22270598bd451b3a1f7165ce 326 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 22 302 1.1E-59 T 13-09-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 PANTHER PTHR24322:SF328 11 130 7.6E-47 T 13-09-2016 THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.6E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 1.6E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 1.6E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 PANTHER PTHR24322 146 178 7.6E-47 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 4.1E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 4.1E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 4.1E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.1E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 4.1E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 4.1E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 Gene3D G3DSA:3.40.50.720 1 240 5.6E-78 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 182 0.0097 T 13-09-2016 THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 SUPERFAMILY SSF51735 6 240 1.8E-74 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 240 4.0E-58 T 13-09-2016 THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 PANTHER PTHR24322 11 130 7.6E-47 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20940 a1ed90c5d595887a688045136ca7f673 242 PANTHER PTHR24322:SF328 146 178 7.6E-47 T 13-09-2016 THL1_RS05340 e914b6fb9ee1d09a37d41d1174b0b1fe 448 PANTHER PTHR30624:SF1 7 448 2.8E-181 T 13-09-2016 THL1_RS05340 e914b6fb9ee1d09a37d41d1174b0b1fe 448 Pfam PF01523 Putative modulator of DNA gyrase 34 325 9.1E-52 T 13-09-2016 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS05340 e914b6fb9ee1d09a37d41d1174b0b1fe 448 SUPERFAMILY SSF111283 14 447 6.54E-125 T 13-09-2016 THL1_RS05340 e914b6fb9ee1d09a37d41d1174b0b1fe 448 PANTHER PTHR30624 7 448 2.8E-181 T 13-09-2016 THL1_RS09780 552c98948a1db325580091f05bc9dd32 225 PANTHER PTHR39328 2 225 2.7E-71 T 13-09-2016 THL1_RS09780 552c98948a1db325580091f05bc9dd32 225 SUPERFAMILY SSF56235 1 225 2.24E-76 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS09780 552c98948a1db325580091f05bc9dd32 225 Pfam PF06267 Family of unknown function (DUF1028) 2 192 2.9E-65 T 13-09-2016 IPR010430 Protein of unknown function DUF1028 THL1_RS09780 552c98948a1db325580091f05bc9dd32 225 Gene3D G3DSA:3.60.20.10 1 215 1.4E-81 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS09780 552c98948a1db325580091f05bc9dd32 225 PANTHER PTHR39328:SF1 2 225 2.7E-71 T 13-09-2016 THL1_RS22200 f3618c1b304f517c67d6af74c439f809 159 PANTHER PTHR10681:SF107 31 146 5.5E-28 T 13-09-2016 THL1_RS22200 f3618c1b304f517c67d6af74c439f809 159 Gene3D G3DSA:3.40.30.10 31 157 8.4E-31 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS22200 f3618c1b304f517c67d6af74c439f809 159 Pfam PF00578 AhpC/TSA family 31 137 8.9E-21 T 13-09-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS22200 f3618c1b304f517c67d6af74c439f809 159 ProSitePatterns PS00194 Thioredoxin family active site. 48 66 - T 13-09-2016 IPR017937 Thioredoxin, conserved site GO:0045454 THL1_RS22200 f3618c1b304f517c67d6af74c439f809 159 PANTHER PTHR10681 31 146 5.5E-28 T 13-09-2016 THL1_RS22200 f3618c1b304f517c67d6af74c439f809 159 SUPERFAMILY SSF52833 16 155 7.42E-29 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS18340 d64bb8d70614cfce47641940fa7dbccc 232 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 59 72 - T 13-09-2016 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS18340 d64bb8d70614cfce47641940fa7dbccc 232 SMART SM00934 7 227 6.9E-99 T 13-09-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS18340 d64bb8d70614cfce47641940fa7dbccc 232 PANTHER PTHR32119 7 231 3.4E-108 T 13-09-2016 THL1_RS18340 d64bb8d70614cfce47641940fa7dbccc 232 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 5 232 38.921 T 13-09-2016 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS18340 d64bb8d70614cfce47641940fa7dbccc 232 SUPERFAMILY SSF51366 5 230 3.24E-72 T 13-09-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 THL1_RS18340 d64bb8d70614cfce47641940fa7dbccc 232 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 9 226 8.0E-57 T 13-09-2016 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS18340 d64bb8d70614cfce47641940fa7dbccc 232 Gene3D G3DSA:3.20.20.70 5 231 9.4E-86 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS18340 d64bb8d70614cfce47641940fa7dbccc 232 PANTHER PTHR32119:SF2 7 231 3.4E-108 T 13-09-2016 THL1_RS18340 d64bb8d70614cfce47641940fa7dbccc 232 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 7 226 1.9E-52 T 13-09-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS05730 395533b0b446c3d481ef5a15becfc40a 159 PANTHER PTHR30476 1 159 2.3E-87 T 13-09-2016 THL1_RS05730 395533b0b446c3d481ef5a15becfc40a 159 Gene3D G3DSA:3.30.70.860 93 159 1.0E-34 T 13-09-2016 THL1_RS05730 395533b0b446c3d481ef5a15becfc40a 159 SUPERFAMILY SSF89963 2 85 3.14E-26 T 13-09-2016 IPR007551 Protein of unknown function DUF520 THL1_RS05730 395533b0b446c3d481ef5a15becfc40a 159 SUPERFAMILY SSF89963 87 159 3.66E-29 T 13-09-2016 IPR007551 Protein of unknown function DUF520 THL1_RS05730 395533b0b446c3d481ef5a15becfc40a 159 Gene3D G3DSA:3.30.70.990 9 92 3.1E-27 T 13-09-2016 THL1_RS05730 395533b0b446c3d481ef5a15becfc40a 159 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 159 27.913 T 13-09-2016 IPR007551 Protein of unknown function DUF520 THL1_RS05730 395533b0b446c3d481ef5a15becfc40a 159 PANTHER PTHR30476:SF0 1 159 2.3E-87 T 13-09-2016 THL1_RS05730 395533b0b446c3d481ef5a15becfc40a 159 Pfam PF04461 Protein of unknown function (DUF520) 2 158 3.2E-62 T 13-09-2016 IPR007551 Protein of unknown function DUF520 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 SUPERFAMILY SSF50677 188 362 4.58E-60 T 13-09-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 PANTHER PTHR11946:SF5 604 858 0.0 T 13-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 Gene3D G3DSA:1.10.730.10 627 814 3.5E-67 T 13-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 PANTHER PTHR11946 604 858 0.0 T 13-09-2016 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 PANTHER PTHR11946 1 311 0.0 T 13-09-2016 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 Gene3D G3DSA:3.90.740.10 191 357 8.8E-48 T 13-09-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 SUPERFAMILY SSF46589 882 946 9.42E-18 T 13-09-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 Pfam PF08264 Anticodon-binding domain of tRNA 670 821 9.6E-43 T 13-09-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 PANTHER PTHR11946:SF5 330 566 0.0 T 13-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 PANTHER PTHR11946:SF5 1 311 0.0 T 13-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 TIGRFAM TIGR00422 valS: valine--tRNA ligase 1 929 0.0 T 13-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 40 51 - T 13-09-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 Gene3D G3DSA:3.40.50.620 361 567 3.7E-141 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 Gene3D G3DSA:3.40.50.620 3 190 3.7E-141 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 Gene3D G3DSA:3.40.50.620 605 626 3.7E-141 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 PANTHER PTHR11946 330 566 0.0 T 13-09-2016 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 PANTHER PTHR11946 878 942 0.0 T 13-09-2016 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 PANTHER PTHR11946:SF5 878 942 0.0 T 13-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 885 946 5.9E-20 T 13-09-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 Hamap MF_02004 Valine--tRNA ligase [valS]. 1 947 16.216 T 13-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 627 3.2E-214 T 13-09-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 Gene3D G3DSA:1.10.287.380 876 946 1.6E-8 T 13-09-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 PRINTS PR00986 Valyl-tRNA synthetase signature 366 379 9.8E-37 T 13-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 PRINTS PR00986 Valyl-tRNA synthetase signature 465 486 9.8E-37 T 13-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 PRINTS PR00986 Valyl-tRNA synthetase signature 33 44 9.8E-37 T 13-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 PRINTS PR00986 Valyl-tRNA synthetase signature 496 514 9.8E-37 T 13-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 PRINTS PR00986 Valyl-tRNA synthetase signature 233 250 9.8E-37 T 13-09-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 SUPERFAMILY SSF47323 638 896 2.06E-70 T 13-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 SUPERFAMILY SSF52374 1 189 4.38E-136 T 13-09-2016 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 SUPERFAMILY SSF52374 361 567 4.38E-136 T 13-09-2016 THL1_RS05835 b024aa8b0bccafe2887ec7789a7a2abc 949 SUPERFAMILY SSF52374 605 637 4.38E-136 T 13-09-2016 THL1_RS09640 91ad2b28d3ca4bb37a8201acb48f2684 724 Gene3D G3DSA:1.20.272.10 243 360 1.4E-45 T 13-09-2016 THL1_RS09640 91ad2b28d3ca4bb37a8201acb48f2684 724 PANTHER PTHR11669 1 370 4.2E-182 T 13-09-2016 THL1_RS09640 91ad2b28d3ca4bb37a8201acb48f2684 724 PANTHER PTHR11669 391 433 4.2E-182 T 13-09-2016 THL1_RS09640 91ad2b28d3ca4bb37a8201acb48f2684 724 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 600 719 9.9E-14 T 13-09-2016 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THL1_RS09640 91ad2b28d3ca4bb37a8201acb48f2684 724 Pfam PF13177 DNA polymerase III, delta subunit 20 178 6.1E-44 T 13-09-2016 THL1_RS09640 91ad2b28d3ca4bb37a8201acb48f2684 724 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 233 360 3.9E-32 T 13-09-2016 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 THL1_RS09640 91ad2b28d3ca4bb37a8201acb48f2684 724 PANTHER PTHR11669:SF0 1 370 4.2E-182 T 13-09-2016 THL1_RS09640 91ad2b28d3ca4bb37a8201acb48f2684 724 PANTHER PTHR11669:SF0 391 433 4.2E-182 T 13-09-2016 THL1_RS09640 91ad2b28d3ca4bb37a8201acb48f2684 724 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 2.2E-5 T 13-09-2016 IPR001270 ClpA/B family GO:0005524 THL1_RS09640 91ad2b28d3ca4bb37a8201acb48f2684 724 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 2.2E-5 T 13-09-2016 IPR001270 ClpA/B family GO:0005524 THL1_RS09640 91ad2b28d3ca4bb37a8201acb48f2684 724 SMART SM00382 37 179 1.1E-6 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS09640 91ad2b28d3ca4bb37a8201acb48f2684 724 Gene3D G3DSA:3.40.50.300 15 166 4.1E-68 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09640 91ad2b28d3ca4bb37a8201acb48f2684 724 SUPERFAMILY SSF48019 243 361 5.78E-33 T 13-09-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 THL1_RS09640 91ad2b28d3ca4bb37a8201acb48f2684 724 Gene3D G3DSA:1.10.8.60 167 242 2.0E-31 T 13-09-2016 THL1_RS09640 91ad2b28d3ca4bb37a8201acb48f2684 724 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 355 2.0E-130 T 13-09-2016 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 THL1_RS09640 91ad2b28d3ca4bb37a8201acb48f2684 724 SUPERFAMILY SSF52540 29 221 8.33E-58 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16035 d71dd3394c819f0767f418a49c9c6c90 202 PANTHER PTHR33798:SF1 1 202 1.9E-93 T 13-09-2016 THL1_RS16035 d71dd3394c819f0767f418a49c9c6c90 202 Pfam PF01613 Flavin reductase like domain 22 165 9.5E-18 T 13-09-2016 IPR002563 Flavin reductase like domain GO:0010181 THL1_RS16035 d71dd3394c819f0767f418a49c9c6c90 202 SMART SM00903 19 176 1.2E-18 T 13-09-2016 IPR002563 Flavin reductase like domain GO:0010181 THL1_RS16035 d71dd3394c819f0767f418a49c9c6c90 202 PANTHER PTHR33798 1 202 1.9E-93 T 13-09-2016 THL1_RS16035 d71dd3394c819f0767f418a49c9c6c90 202 SUPERFAMILY SSF50475 2 198 4.97E-44 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS16035 d71dd3394c819f0767f418a49c9c6c90 202 Gene3D G3DSA:2.30.110.10 12 190 1.5E-60 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS18195 fd750f76d6377c6450b94751d75ad6af 178 PANTHER PTHR38037 1 178 6.9E-53 T 13-09-2016 THL1_RS18195 fd750f76d6377c6450b94751d75ad6af 178 Pfam PF05618 Putative ATP-dependant zinc protease 26 167 1.3E-47 T 13-09-2016 THL1_RS18195 fd750f76d6377c6450b94751d75ad6af 178 SUPERFAMILY SSF50630 26 164 3.54E-39 T 13-09-2016 IPR021109 Aspartic peptidase domain THL1_RS18195 fd750f76d6377c6450b94751d75ad6af 178 Gene3D G3DSA:2.40.70.10 23 159 1.1E-44 T 13-09-2016 IPR021109 Aspartic peptidase domain THL1_RS23510 3fa4d4272c907e5daa7cf7ba640f587a 333 Gene3D G3DSA:3.40.50.970 9 201 2.2E-73 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS23510 3fa4d4272c907e5daa7cf7ba640f587a 333 Pfam PF02780 Transketolase, C-terminal domain 205 322 1.0E-38 T 13-09-2016 IPR033248 Transketolase, C-terminal domain THL1_RS23510 3fa4d4272c907e5daa7cf7ba640f587a 333 SUPERFAMILY SSF52922 197 331 2.22E-39 T 13-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THL1_RS23510 3fa4d4272c907e5daa7cf7ba640f587a 333 Pfam PF02779 Transketolase, pyrimidine binding domain 12 186 6.7E-49 T 13-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain THL1_RS23510 3fa4d4272c907e5daa7cf7ba640f587a 333 SMART SM00861 11 186 3.9E-59 T 13-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain THL1_RS23510 3fa4d4272c907e5daa7cf7ba640f587a 333 Gene3D G3DSA:3.40.50.920 206 326 3.5E-46 T 13-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THL1_RS23510 3fa4d4272c907e5daa7cf7ba640f587a 333 SUPERFAMILY SSF52518 12 194 2.36E-62 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS23510 3fa4d4272c907e5daa7cf7ba640f587a 333 PANTHER PTHR11624 1 332 1.0E-141 T 13-09-2016 IPR033247 Transketolase family THL1_RS23510 3fa4d4272c907e5daa7cf7ba640f587a 333 PANTHER PTHR11624:SF79 1 332 1.0E-141 T 13-09-2016 THL1_RS27820 e7905e3700addbad3bae663ad94a7f22 224 Gene3D G3DSA:3.40.140.10 101 224 3.3E-50 T 13-09-2016 THL1_RS27820 e7905e3700addbad3bae663ad94a7f22 224 SUPERFAMILY SSF102712 108 199 4.05E-6 T 13-09-2016 THL1_RS27820 e7905e3700addbad3bae663ad94a7f22 224 SUPERFAMILY SSF47781 17 90 6.04E-11 T 13-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 THL1_RS27820 e7905e3700addbad3bae663ad94a7f22 224 PANTHER PTHR30471:SF5 1 224 4.0E-134 T 13-09-2016 THL1_RS27820 e7905e3700addbad3bae663ad94a7f22 224 Pfam PF04002 RadC-like JAB domain 104 222 1.1E-44 T 13-09-2016 IPR025657 RadC-like JAB domain THL1_RS27820 e7905e3700addbad3bae663ad94a7f22 224 PANTHER PTHR30471 1 224 4.0E-134 T 13-09-2016 THL1_RS27820 e7905e3700addbad3bae663ad94a7f22 224 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 13-09-2016 IPR020891 Uncharacterised protein family UPF0758, conserved site THL1_RS27820 e7905e3700addbad3bae663ad94a7f22 224 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 224 3.7E-75 T 13-09-2016 IPR001405 RadC protein THL1_RS21660 c7369cbb73d2cab89c79965307f3092b 561 Pfam PF05199 GMC oxidoreductase 387 523 3.2E-41 T 13-09-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 THL1_RS21660 c7369cbb73d2cab89c79965307f3092b 561 PANTHER PTHR11552 1 549 1.1E-233 T 13-09-2016 THL1_RS21660 c7369cbb73d2cab89c79965307f3092b 561 PANTHER PTHR11552:SF51 1 549 1.1E-233 T 13-09-2016 THL1_RS21660 c7369cbb73d2cab89c79965307f3092b 561 SUPERFAMILY SSF51905 2 289 7.03E-90 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21660 c7369cbb73d2cab89c79965307f3092b 561 SUPERFAMILY SSF51905 472 531 7.03E-90 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21660 c7369cbb73d2cab89c79965307f3092b 561 Pfam PF00732 GMC oxidoreductase 5 296 3.1E-92 T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS21660 c7369cbb73d2cab89c79965307f3092b 561 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 255 269 - T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS21660 c7369cbb73d2cab89c79965307f3092b 561 Gene3D G3DSA:3.50.50.60 466 530 3.5E-122 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21660 c7369cbb73d2cab89c79965307f3092b 561 Gene3D G3DSA:3.50.50.60 3 126 3.5E-122 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21660 c7369cbb73d2cab89c79965307f3092b 561 Gene3D G3DSA:3.50.50.60 188 314 3.5E-122 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21660 c7369cbb73d2cab89c79965307f3092b 561 SUPERFAMILY SSF54373 291 473 4.41E-61 T 13-09-2016 THL1_RS21660 c7369cbb73d2cab89c79965307f3092b 561 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 82 105 - T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS21660 c7369cbb73d2cab89c79965307f3092b 561 TIGRFAM TIGR01810 betA: choline dehydrogenase 6 533 1.5E-235 T 13-09-2016 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|UniPathway: UPA00529 THL1_RS08270 eea97bc62fd2726b7a69512ca88dca1e 318 Pfam PF03466 LysR substrate binding domain 88 294 7.4E-36 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS08270 eea97bc62fd2726b7a69512ca88dca1e 318 PANTHER PTHR30126:SF26 1 309 5.4E-145 T 13-09-2016 THL1_RS08270 eea97bc62fd2726b7a69512ca88dca1e 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 2.6E-20 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08270 eea97bc62fd2726b7a69512ca88dca1e 318 SUPERFAMILY SSF46785 6 86 6.86E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08270 eea97bc62fd2726b7a69512ca88dca1e 318 Gene3D G3DSA:1.10.10.10 6 86 9.1E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08270 eea97bc62fd2726b7a69512ca88dca1e 318 PANTHER PTHR30126 1 309 5.4E-145 T 13-09-2016 THL1_RS08270 eea97bc62fd2726b7a69512ca88dca1e 318 SUPERFAMILY SSF53850 90 298 3.98E-37 T 13-09-2016 THL1_RS08270 eea97bc62fd2726b7a69512ca88dca1e 318 Gene3D G3DSA:3.40.190.10 179 262 1.1E-16 T 13-09-2016 THL1_RS08270 eea97bc62fd2726b7a69512ca88dca1e 318 Gene3D G3DSA:3.40.190.10 92 178 1.8E-16 T 13-09-2016 THL1_RS04580 39e1f3b16d221787ef9dcdd2c3add980 289 PANTHER PTHR11066:SF34 5 287 5.7E-115 T 13-09-2016 THL1_RS04580 39e1f3b16d221787ef9dcdd2c3add980 289 SUPERFAMILY SSF54637 116 283 6.68E-61 T 13-09-2016 IPR029069 HotDog domain THL1_RS04580 39e1f3b16d221787ef9dcdd2c3add980 289 Pfam PF13622 Thioesterase-like superfamily 33 281 4.6E-62 T 13-09-2016 THL1_RS04580 39e1f3b16d221787ef9dcdd2c3add980 289 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 12 283 2.9E-90 T 13-09-2016 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 THL1_RS04580 39e1f3b16d221787ef9dcdd2c3add980 289 Gene3D G3DSA:3.10.129.10 5 115 4.0E-48 T 13-09-2016 IPR029069 HotDog domain THL1_RS04580 39e1f3b16d221787ef9dcdd2c3add980 289 SUPERFAMILY SSF54637 4 114 6.34E-41 T 13-09-2016 IPR029069 HotDog domain THL1_RS04580 39e1f3b16d221787ef9dcdd2c3add980 289 PANTHER PTHR11066 5 287 5.7E-115 T 13-09-2016 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 THL1_RS04580 39e1f3b16d221787ef9dcdd2c3add980 289 Gene3D G3DSA:3.10.129.10 124 285 7.2E-59 T 13-09-2016 IPR029069 HotDog domain THL1_RS22915 76b4c5f60e04ba667a613d08c3df33b2 168 SMART SM00260 13 152 5.8E-12 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS22915 76b4c5f60e04ba667a613d08c3df33b2 168 Pfam PF01584 CheW-like domain 18 153 3.4E-25 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS22915 76b4c5f60e04ba667a613d08c3df33b2 168 PANTHER PTHR22617:SF33 19 168 1.1E-43 T 13-09-2016 THL1_RS22915 76b4c5f60e04ba667a613d08c3df33b2 168 SUPERFAMILY SSF50341 18 156 1.96E-26 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS22915 76b4c5f60e04ba667a613d08c3df33b2 168 PANTHER PTHR22617 19 168 1.1E-43 T 13-09-2016 THL1_RS26020 f07cb633bc272ea0d1efb78aecff9fb4 651 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 389 414 1.8E-5 T 13-09-2016 THL1_RS26020 f07cb633bc272ea0d1efb78aecff9fb4 651 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 473 487 1.8E-5 T 13-09-2016 THL1_RS26020 f07cb633bc272ea0d1efb78aecff9fb4 651 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 388 617 6.8E-16 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS26020 f07cb633bc272ea0d1efb78aecff9fb4 651 Gene3D G3DSA:3.20.20.70 4 378 6.8E-106 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS26020 f07cb633bc272ea0d1efb78aecff9fb4 651 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 9 342 4.1E-56 T 13-09-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 THL1_RS26020 f07cb633bc272ea0d1efb78aecff9fb4 651 SUPERFAMILY SSF51905 475 631 3.33E-21 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS26020 f07cb633bc272ea0d1efb78aecff9fb4 651 PANTHER PTHR22893 1 430 3.2E-200 T 13-09-2016 THL1_RS26020 f07cb633bc272ea0d1efb78aecff9fb4 651 PANTHER PTHR22893:SF7 1 430 3.2E-200 T 13-09-2016 THL1_RS26020 f07cb633bc272ea0d1efb78aecff9fb4 651 Gene3D G3DSA:3.50.50.60 483 616 1.1E-24 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS26020 f07cb633bc272ea0d1efb78aecff9fb4 651 SUPERFAMILY SSF51971 345 540 2.47E-31 T 13-09-2016 THL1_RS26020 f07cb633bc272ea0d1efb78aecff9fb4 651 SUPERFAMILY SSF51395 4 371 1.14E-93 T 13-09-2016 THL1_RS26020 f07cb633bc272ea0d1efb78aecff9fb4 651 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 390 409 1.7E-7 T 13-09-2016 THL1_RS26020 f07cb633bc272ea0d1efb78aecff9fb4 651 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 472 490 1.7E-7 T 13-09-2016 THL1_RS26020 f07cb633bc272ea0d1efb78aecff9fb4 651 Gene3D G3DSA:3.50.50.60 617 651 8.2E-23 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS26020 f07cb633bc272ea0d1efb78aecff9fb4 651 Gene3D G3DSA:3.50.50.60 385 482 8.2E-23 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27570 2a8723143a522453054149cf39c36ce2 269 PANTHER PTHR20854 76 236 3.2E-19 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS27570 2a8723143a522453054149cf39c36ce2 269 Gene3D G3DSA:3.40.190.80 165 253 4.5E-11 T 13-09-2016 THL1_RS27570 2a8723143a522453054149cf39c36ce2 269 Gene3D G3DSA:3.30.540.10 39 137 4.2E-20 T 13-09-2016 THL1_RS27570 2a8723143a522453054149cf39c36ce2 269 Pfam PF00459 Inositol monophosphatase family 39 241 3.2E-23 T 13-09-2016 IPR000760 Inositol monophosphatase GO:0046854 THL1_RS27570 2a8723143a522453054149cf39c36ce2 269 SUPERFAMILY SSF56655 5 246 7.07E-35 T 13-09-2016 THL1_RS27570 2a8723143a522453054149cf39c36ce2 269 PANTHER PTHR20854:SF5 76 236 3.2E-19 T 13-09-2016 THL1_RS01445 792f793f8ee621d3c5f0a23e864f78c7 110 Pfam PF07411 Domain of unknown function (DUF1508) 11 52 1.3E-18 T 13-09-2016 IPR010879 Domain of unknown function DUF1508 THL1_RS01445 792f793f8ee621d3c5f0a23e864f78c7 110 Pfam PF07411 Domain of unknown function (DUF1508) 61 108 2.0E-22 T 13-09-2016 IPR010879 Domain of unknown function DUF1508 THL1_RS01445 792f793f8ee621d3c5f0a23e864f78c7 110 SUPERFAMILY SSF160113 1 53 6.8E-17 T 13-09-2016 IPR010879 Domain of unknown function DUF1508 THL1_RS01445 792f793f8ee621d3c5f0a23e864f78c7 110 SUPERFAMILY SSF160113 54 108 2.35E-17 T 13-09-2016 IPR010879 Domain of unknown function DUF1508 THL1_RS01445 792f793f8ee621d3c5f0a23e864f78c7 110 PANTHER PTHR40606:SF1 2 110 1.4E-61 T 13-09-2016 THL1_RS01445 792f793f8ee621d3c5f0a23e864f78c7 110 PANTHER PTHR40606 2 110 1.4E-61 T 13-09-2016 THL1_RS01445 792f793f8ee621d3c5f0a23e864f78c7 110 Gene3D G3DSA:3.30.160.160 3 49 1.1E-20 T 13-09-2016 IPR010879 Domain of unknown function DUF1508 THL1_RS01445 792f793f8ee621d3c5f0a23e864f78c7 110 Gene3D G3DSA:3.30.160.160 55 100 8.5E-21 T 13-09-2016 IPR010879 Domain of unknown function DUF1508 THL1_RS09505 a534d5241323635d90d6154e07a0a7e1 256 SMART SM00345 27 85 7.6E-18 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS09505 a534d5241323635d90d6154e07a0a7e1 256 Pfam PF07729 FCD domain 95 217 1.9E-24 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS09505 a534d5241323635d90d6154e07a0a7e1 256 SUPERFAMILY SSF48008 90 220 1.33E-28 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS09505 a534d5241323635d90d6154e07a0a7e1 256 PANTHER PTHR11751 24 111 1.0E-25 T 13-09-2016 THL1_RS09505 a534d5241323635d90d6154e07a0a7e1 256 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 85 7.2E-18 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS09505 a534d5241323635d90d6154e07a0a7e1 256 Gene3D G3DSA:1.10.10.10 8 86 3.1E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09505 a534d5241323635d90d6154e07a0a7e1 256 SMART SM00895 95 218 2.3E-22 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS09505 a534d5241323635d90d6154e07a0a7e1 256 SUPERFAMILY SSF46785 21 89 8.19E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09505 a534d5241323635d90d6154e07a0a7e1 256 Gene3D G3DSA:1.20.120.530 88 223 1.2E-32 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS09505 a534d5241323635d90d6154e07a0a7e1 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 1.8E-5 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS09505 a534d5241323635d90d6154e07a0a7e1 256 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 1.8E-5 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS15420 8b2619c611dd3bc80825c7ca44bfa5c8 108 Gene3D G3DSA:3.30.70.120 1 103 3.8E-29 T 13-09-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THL1_RS15420 8b2619c611dd3bc80825c7ca44bfa5c8 108 PANTHER PTHR35983 1 85 6.2E-13 T 13-09-2016 THL1_RS15420 8b2619c611dd3bc80825c7ca44bfa5c8 108 SUPERFAMILY SSF54913 1 100 1.78E-29 T 13-09-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta THL1_RS15420 8b2619c611dd3bc80825c7ca44bfa5c8 108 Pfam PF02641 Uncharacterized ACR, COG1993 5 85 6.6E-18 T 13-09-2016 IPR003793 Domain of unknown function DUF190 THL1_RS17360 c9d83f6e631a880374dee659a05d68ba 282 SUPERFAMILY SSF161098 14 281 1.13E-56 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS17360 c9d83f6e631a880374dee659a05d68ba 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 271 3.0E-17 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS17360 c9d83f6e631a880374dee659a05d68ba 282 PANTHER PTHR30193 21 282 2.2E-72 T 13-09-2016 THL1_RS17360 c9d83f6e631a880374dee659a05d68ba 282 PANTHER PTHR30193:SF20 21 282 2.2E-72 T 13-09-2016 THL1_RS17360 c9d83f6e631a880374dee659a05d68ba 282 Gene3D G3DSA:1.10.3720.10 20 274 7.2E-55 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS26035 a2ba18beaa51d43462db75aa30201e6e 294 SUPERFAMILY SSF46785 4 88 9.8E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS26035 a2ba18beaa51d43462db75aa30201e6e 294 PANTHER PTHR30419 1 293 2.2E-127 T 13-09-2016 THL1_RS26035 a2ba18beaa51d43462db75aa30201e6e 294 Pfam PF03466 LysR substrate binding domain 91 290 3.3E-26 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS26035 a2ba18beaa51d43462db75aa30201e6e 294 Gene3D G3DSA:3.40.190.10 91 177 1.3E-8 T 13-09-2016 THL1_RS26035 a2ba18beaa51d43462db75aa30201e6e 294 Gene3D G3DSA:1.10.10.10 2 82 4.5E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS26035 a2ba18beaa51d43462db75aa30201e6e 294 PANTHER PTHR30419:SF11 1 293 2.2E-127 T 13-09-2016 THL1_RS26035 a2ba18beaa51d43462db75aa30201e6e 294 Gene3D G3DSA:3.40.190.10 178 258 6.0E-8 T 13-09-2016 THL1_RS26035 a2ba18beaa51d43462db75aa30201e6e 294 SUPERFAMILY SSF53850 92 292 5.43E-31 T 13-09-2016 THL1_RS26035 a2ba18beaa51d43462db75aa30201e6e 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 9.8E-18 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS26035 a2ba18beaa51d43462db75aa30201e6e 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.2E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS26035 a2ba18beaa51d43462db75aa30201e6e 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.2E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS26035 a2ba18beaa51d43462db75aa30201e6e 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.2E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS11450 469e0e76b70f7fa27ae7618890a31144 411 PANTHER PTHR22893:SF6 4 345 1.1E-143 T 13-09-2016 THL1_RS11450 469e0e76b70f7fa27ae7618890a31144 411 Gene3D G3DSA:3.20.20.70 4 342 6.7E-101 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS11450 469e0e76b70f7fa27ae7618890a31144 411 SUPERFAMILY SSF51395 4 342 1.5E-93 T 13-09-2016 THL1_RS11450 469e0e76b70f7fa27ae7618890a31144 411 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 333 3.3E-45 T 13-09-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 THL1_RS11450 469e0e76b70f7fa27ae7618890a31144 411 PANTHER PTHR22893 4 345 1.1E-143 T 13-09-2016 THL1_RS11165 37aa152c86dc0cc81d28d3484cb55f52 350 PANTHER PTHR17630 211 350 2.5E-82 T 13-09-2016 THL1_RS11165 37aa152c86dc0cc81d28d3484cb55f52 350 Pfam PF01738 Dienelactone hydrolase family 62 180 1.0E-8 T 13-09-2016 IPR002925 Dienelactone hydrolase GO:0016787 THL1_RS11165 37aa152c86dc0cc81d28d3484cb55f52 350 Gene3D G3DSA:3.40.50.1820 51 350 1.1E-58 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS11165 37aa152c86dc0cc81d28d3484cb55f52 350 SUPERFAMILY SSF53474 44 192 3.66E-42 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS11165 37aa152c86dc0cc81d28d3484cb55f52 350 SUPERFAMILY SSF53474 242 349 3.66E-42 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS11165 37aa152c86dc0cc81d28d3484cb55f52 350 PANTHER PTHR17630:SF49 211 350 2.5E-82 T 13-09-2016 THL1_RS11165 37aa152c86dc0cc81d28d3484cb55f52 350 PANTHER PTHR17630 32 191 2.5E-82 T 13-09-2016 THL1_RS11165 37aa152c86dc0cc81d28d3484cb55f52 350 PANTHER PTHR17630:SF49 32 191 2.5E-82 T 13-09-2016 THL1_RS21200 dd5cd143402144c22292e30327b2c053 406 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 14 401 46.188 T 13-09-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 THL1_RS21200 dd5cd143402144c22292e30327b2c053 406 Gene3D G3DSA:3.40.640.10 61 303 6.9E-93 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS21200 dd5cd143402144c22292e30327b2c053 406 PANTHER PTHR11986:SF71 1 406 7.2E-220 T 13-09-2016 THL1_RS21200 dd5cd143402144c22292e30327b2c053 406 Pfam PF00202 Aminotransferase class-III 21 400 9.2E-126 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS21200 dd5cd143402144c22292e30327b2c053 406 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 17 400 3.2E-155 T 13-09-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 THL1_RS21200 dd5cd143402144c22292e30327b2c053 406 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 223 260 - T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS21200 dd5cd143402144c22292e30327b2c053 406 TIGRFAM TIGR03246 arg_catab_astC: succinylornithine transaminase family 8 403 3.9E-218 T 13-09-2016 IPR017652 Acetyl/Succinylornithine transaminase family, bacteria GO:0006520|GO:0008483|GO:0030170 THL1_RS21200 dd5cd143402144c22292e30327b2c053 406 Gene3D G3DSA:3.90.1150.10 14 60 2.1E-34 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS21200 dd5cd143402144c22292e30327b2c053 406 Gene3D G3DSA:3.90.1150.10 307 402 2.1E-34 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS21200 dd5cd143402144c22292e30327b2c053 406 SUPERFAMILY SSF53383 17 402 3.36E-129 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS21200 dd5cd143402144c22292e30327b2c053 406 PANTHER PTHR11986 1 406 7.2E-220 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS09740 4db8d9340157a2f1ee951e1514b1c50d 377 Pfam PF13426 PAS domain 21 93 0.016 T 13-09-2016 IPR000014 PAS domain THL1_RS09740 4db8d9340157a2f1ee951e1514b1c50d 377 Pfam PF13188 PAS domain 274 324 2.6E-4 T 13-09-2016 IPR000014 PAS domain THL1_RS09740 4db8d9340157a2f1ee951e1514b1c50d 377 SMART SM00091 2 68 42.0 T 13-09-2016 IPR000014 PAS domain THL1_RS09740 4db8d9340157a2f1ee951e1514b1c50d 377 SMART SM00091 272 337 0.15 T 13-09-2016 IPR000014 PAS domain THL1_RS09740 4db8d9340157a2f1ee951e1514b1c50d 377 Gene3D G3DSA:3.30.450.20 121 258 3.6E-5 T 13-09-2016 THL1_RS09740 4db8d9340157a2f1ee951e1514b1c50d 377 SUPERFAMILY SSF55785 17 96 2.79E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS09740 4db8d9340157a2f1ee951e1514b1c50d 377 SUPERFAMILY SSF55785 168 264 2.79E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS09740 4db8d9340157a2f1ee951e1514b1c50d 377 Gene3D G3DSA:3.30.450.20 269 319 1.6E-7 T 13-09-2016 THL1_RS09740 4db8d9340157a2f1ee951e1514b1c50d 377 Gene3D G3DSA:3.30.450.20 19 93 4.4E-6 T 13-09-2016 THL1_RS09740 4db8d9340157a2f1ee951e1514b1c50d 377 SUPERFAMILY SSF55785 256 325 8.55E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS11095 acefd4d0469423c290c832f585c1ba34 158 PANTHER PTHR31757:SF0 2 158 1.1E-89 T 13-09-2016 THL1_RS11095 acefd4d0469423c290c832f585c1ba34 158 Pfam PF07080 Protein of unknown function (DUF1348) 7 148 1.6E-70 T 13-09-2016 IPR009783 Protein of unknown function DUF1348 THL1_RS11095 acefd4d0469423c290c832f585c1ba34 158 SUPERFAMILY SSF54427 5 158 3.19E-77 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS11095 acefd4d0469423c290c832f585c1ba34 158 Gene3D G3DSA:3.10.450.50 14 156 2.2E-74 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS11095 acefd4d0469423c290c832f585c1ba34 158 PANTHER PTHR31757 2 158 1.1E-89 T 13-09-2016 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 Gene3D G3DSA:3.30.70.100 8 68 6.0E-23 T 13-09-2016 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 Gene3D G3DSA:3.30.70.100 73 139 4.9E-24 T 13-09-2016 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 PANTHER PTHR24093 8 794 0.0 T 13-09-2016 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 Gene3D G3DSA:3.40.50.1000 455 499 1.4E-52 T 13-09-2016 IPR023214 HAD-like domain THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 Gene3D G3DSA:3.40.50.1000 613 753 1.4E-52 T 13-09-2016 IPR023214 HAD-like domain THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 PRINTS PR00941 Cadmium-transporting ATPase signature 86 107 1.2E-6 T 13-09-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 PRINTS PR00941 Cadmium-transporting ATPase signature 369 383 1.2E-6 T 13-09-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 PRINTS PR00941 Cadmium-transporting ATPase signature 350 366 1.2E-6 T 13-09-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 PRINTS PR00941 Cadmium-transporting ATPase signature 9 18 1.2E-6 T 13-09-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 Pfam PF00403 Heavy-metal-associated domain 75 133 2.9E-14 T 13-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 Pfam PF00403 Heavy-metal-associated domain 10 67 1.3E-15 T 13-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 Gene3D G3DSA:2.70.150.10 226 385 3.3E-26 T 13-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 ProSitePatterns PS01229 Hypothetical cof family signature 2. 685 707 - T 13-09-2016 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 201 788 1.5E-177 T 13-09-2016 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 257 505 5.7E-43 T 13-09-2016 IPR001757 P-type ATPase GO:0016021 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 605 766 1.7E-40 T 13-09-2016 IPR001757 P-type ATPase GO:0016021 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 Pfam PF00702 haloacid dehalogenase-like hydrolase 481 699 5.7E-41 T 13-09-2016 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 PANTHER PTHR24093:SF332 8 794 0.0 T 13-09-2016 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 SUPERFAMILY SSF81653 287 384 3.79E-24 T 13-09-2016 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 708 720 1.4E-21 T 13-09-2016 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 334 348 1.4E-21 T 13-09-2016 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 484 498 1.4E-21 T 13-09-2016 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 685 704 1.4E-21 T 13-09-2016 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 632 642 1.4E-21 T 13-09-2016 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 ProSitePatterns PS01047 Heavy-metal-associated domain. 77 106 - T 13-09-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 SUPERFAMILY SSF55008 7 68 8.38E-18 T 13-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 219 787 1.5E-187 T 13-09-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 74 135 4.9E-9 T 13-09-2016 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 Pfam PF00122 E1-E2 ATPase 255 475 5.2E-66 T 13-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 ProSitePatterns PS01047 Heavy-metal-associated domain. 11 40 - T 13-09-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 486 492 - T 13-09-2016 IPR018303 P-type ATPase, phosphorylation site THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 SUPERFAMILY SSF81665 385 478 2.48E-15 T 13-09-2016 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 SUPERFAMILY SSF81665 252 288 2.48E-15 T 13-09-2016 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 SUPERFAMILY SSF81665 734 758 2.48E-15 T 13-09-2016 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 Gene3D G3DSA:3.40.1110.10 500 612 3.9E-15 T 13-09-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 SUPERFAMILY SSF56784 540 785 1.07E-57 T 13-09-2016 IPR023214 HAD-like domain THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 SUPERFAMILY SSF56784 483 502 1.07E-57 T 13-09-2016 IPR023214 HAD-like domain THL1_RS25105 65faf5ae8d71820a7bf02edb7a438191 794 SUPERFAMILY SSF55008 71 143 1.31E-19 T 13-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THL1_RS06280 8fbba936905c84c180f9f348eb4ac57e 365 Pfam PF05426 Alginate lyase 59 299 7.4E-58 T 13-09-2016 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 THL1_RS06280 8fbba936905c84c180f9f348eb4ac57e 365 SUPERFAMILY SSF48230 29 357 1.46E-56 T 13-09-2016 IPR008929 Chondroitin AC/alginate lyase THL1_RS06280 8fbba936905c84c180f9f348eb4ac57e 365 Gene3D G3DSA:1.50.10.110 21 358 1.0E-92 T 13-09-2016 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 THL1_RS06280 8fbba936905c84c180f9f348eb4ac57e 365 Hamap MF_00557 Alginate lyase [algL]. 2 365 56.408 T 13-09-2016 IPR022859 Alginate lyase GO:0042122|GO:0042597|GO:0045135 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 Pfam PF02743 Cache domain 39 224 1.8E-12 T 13-09-2016 IPR033479 Double Cache domain 1 THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 SUPERFAMILY SSF47384 352 436 1.14E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 Gene3D G3DSA:1.10.287.130 367 433 3.4E-7 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 SMART SM00387 479 590 1.3E-20 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 PANTHER PTHR24423:SF469 313 600 4.2E-155 T 13-09-2016 THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 PANTHER PTHR24423:SF469 11 50 4.2E-155 T 13-09-2016 THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 PANTHER PTHR24423:SF469 184 246 4.2E-155 T 13-09-2016 THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 481 586 1.2E-15 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 SUPERFAMILY SSF55874 424 586 3.54E-34 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 Gene3D G3DSA:3.30.450.20 70 190 5.7E-4 T 13-09-2016 THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 PIRSF PIRSF036431 3 594 2.9E-198 T 13-09-2016 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 Gene3D G3DSA:3.30.565.10 439 585 7.2E-32 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 PANTHER PTHR24423 313 600 4.2E-155 T 13-09-2016 THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 PANTHER PTHR24423 11 50 4.2E-155 T 13-09-2016 THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 SMART SM00388 369 437 1.1E-6 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 SUPERFAMILY SSF103190 60 193 1.08E-20 T 13-09-2016 IPR029151 Periplasmic sensor domain-like THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 537 547 3.9E-7 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 533 3.9E-7 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 PRINTS PR00344 Bacterial sensor protein C-terminal signature 550 568 3.9E-7 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 PANTHER PTHR24423 184 246 4.2E-155 T 13-09-2016 THL1_RS26985 729a59b3627aa77a73482997a5608e86 603 Pfam PF00512 His Kinase A (phospho-acceptor) domain 369 435 4.3E-8 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS02380 c6ee2384b8fc1552dd439f2e02030bcd 208 SUPERFAMILY SSF52833 42 174 9.61E-27 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS02380 c6ee2384b8fc1552dd439f2e02030bcd 208 PANTHER PTHR12151:SF10 39 163 3.3E-24 T 13-09-2016 THL1_RS02380 c6ee2384b8fc1552dd439f2e02030bcd 208 PANTHER PTHR12151 39 163 3.3E-24 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS02380 c6ee2384b8fc1552dd439f2e02030bcd 208 Pfam PF02630 SCO1/SenC 58 144 2.7E-10 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS02380 c6ee2384b8fc1552dd439f2e02030bcd 208 Gene3D G3DSA:3.40.30.10 17 174 1.1E-26 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS03350 c057d084de493e954a4168e74f828d95 262 PANTHER PTHR24322 7 136 1.5E-49 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS03350 c057d084de493e954a4168e74f828d95 262 PANTHER PTHR24322 152 184 1.5E-49 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS03350 c057d084de493e954a4168e74f828d95 262 PANTHER PTHR24322:SF330 7 136 1.5E-49 T 13-09-2016 THL1_RS03350 c057d084de493e954a4168e74f828d95 262 PANTHER PTHR24322:SF330 152 184 1.5E-49 T 13-09-2016 THL1_RS03350 c057d084de493e954a4168e74f828d95 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 6.8E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS03350 c057d084de493e954a4168e74f828d95 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 6.8E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS03350 c057d084de493e954a4168e74f828d95 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 6.8E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS03350 c057d084de493e954a4168e74f828d95 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 6.8E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS03350 c057d084de493e954a4168e74f828d95 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 6.8E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS03350 c057d084de493e954a4168e74f828d95 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.5E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS03350 c057d084de493e954a4168e74f828d95 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.5E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS03350 c057d084de493e954a4168e74f828d95 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.5E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS03350 c057d084de493e954a4168e74f828d95 262 Pfam PF00106 short chain dehydrogenase 4 192 1.1E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS03350 c057d084de493e954a4168e74f828d95 262 PIRSF PIRSF000126 1 261 2.5E-67 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS03350 c057d084de493e954a4168e74f828d95 262 SUPERFAMILY SSF51735 3 254 1.2E-60 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS03350 c057d084de493e954a4168e74f828d95 262 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 186 0.0038 T 13-09-2016 THL1_RS03350 c057d084de493e954a4168e74f828d95 262 Gene3D G3DSA:3.40.50.720 3 255 6.0E-57 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS14135 7f8f9700549b863039acc0e8f9a59eee 388 SMART SM01204 236 367 4.7E-33 T 13-09-2016 IPR019494 FIST, C-domain THL1_RS14135 7f8f9700549b863039acc0e8f9a59eee 388 PANTHER PTHR40252 2 388 1.2E-144 T 13-09-2016 THL1_RS14135 7f8f9700549b863039acc0e8f9a59eee 388 SMART SM00897 33 235 4.8E-59 T 13-09-2016 IPR013702 FIST domain, N-terminal THL1_RS14135 7f8f9700549b863039acc0e8f9a59eee 388 Pfam PF10442 FIST C domain 236 365 1.7E-14 T 13-09-2016 IPR019494 FIST, C-domain THL1_RS14135 7f8f9700549b863039acc0e8f9a59eee 388 Pfam PF08495 FIST N domain 37 233 1.6E-34 T 13-09-2016 IPR013702 FIST domain, N-terminal THL1_RS14135 7f8f9700549b863039acc0e8f9a59eee 388 PANTHER PTHR40252:SF2 2 388 1.2E-144 T 13-09-2016 THL1_RS17945 7eec7dafb8ff1620c5c524ded7f7c41d 339 SUPERFAMILY SSF161098 136 322 1.96E-19 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS17945 7eec7dafb8ff1620c5c524ded7f7c41d 339 Gene3D G3DSA:1.10.3720.10 132 337 1.2E-20 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS17945 7eec7dafb8ff1620c5c524ded7f7c41d 339 PANTHER PTHR30325 1 339 2.7E-202 T 13-09-2016 THL1_RS17945 7eec7dafb8ff1620c5c524ded7f7c41d 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 158 338 8.9E-26 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS08930 a1b331be4162ac5c674d7cbef39f81be 381 Pfam PF01548 Transposase 70 180 1.1E-8 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS08930 a1b331be4162ac5c674d7cbef39f81be 381 PANTHER PTHR33055:SF3 200 371 4.6E-21 T 13-09-2016 THL1_RS08930 a1b331be4162ac5c674d7cbef39f81be 381 PANTHER PTHR33055:SF3 75 184 4.6E-21 T 13-09-2016 THL1_RS08930 a1b331be4162ac5c674d7cbef39f81be 381 Pfam PF02371 Transposase IS116/IS110/IS902 family 250 329 2.0E-15 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS08930 a1b331be4162ac5c674d7cbef39f81be 381 PANTHER PTHR33055 200 371 4.6E-21 T 13-09-2016 THL1_RS08930 a1b331be4162ac5c674d7cbef39f81be 381 PANTHER PTHR33055 75 184 4.6E-21 T 13-09-2016 THL1_RS20290 a732555ce83810874cff096494c8a4d1 339 Gene3D G3DSA:3.40.190.10 2 122 4.5E-43 T 13-09-2016 THL1_RS20290 a732555ce83810874cff096494c8a4d1 339 Gene3D G3DSA:3.40.190.10 263 322 4.5E-43 T 13-09-2016 THL1_RS20290 a732555ce83810874cff096494c8a4d1 339 PANTHER PTHR30006:SF9 8 338 1.6E-131 T 13-09-2016 THL1_RS20290 a732555ce83810874cff096494c8a4d1 339 TIGRFAM TIGR03261 phnS2: putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein 6 335 3.9E-161 T 13-09-2016 IPR017663 ABC transport system, 1-aminoethylphosphonate-binding protein, putative THL1_RS20290 a732555ce83810874cff096494c8a4d1 339 PIRSF PIRSF002825 1 331 5.4E-92 T 13-09-2016 IPR026045 Ferric binding protein THL1_RS20290 a732555ce83810874cff096494c8a4d1 339 PANTHER PTHR30006 8 338 1.6E-131 T 13-09-2016 THL1_RS20290 a732555ce83810874cff096494c8a4d1 339 Pfam PF13343 Bacterial extracellular solute-binding protein 75 311 3.6E-28 T 13-09-2016 THL1_RS20290 a732555ce83810874cff096494c8a4d1 339 SUPERFAMILY SSF53850 20 328 8.03E-70 T 13-09-2016 THL1_RS20290 a732555ce83810874cff096494c8a4d1 339 Gene3D G3DSA:3.40.190.10 125 262 1.3E-43 T 13-09-2016 THL1_RS18600 acfe88aac94296abfb3ae23cb65a4cf5 799 SUPERFAMILY SSF53335 6 490 3.59E-126 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS18600 acfe88aac94296abfb3ae23cb65a4cf5 799 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 301 325 4.1E-23 T 13-09-2016 THL1_RS18600 acfe88aac94296abfb3ae23cb65a4cf5 799 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 264 276 4.1E-23 T 13-09-2016 THL1_RS18600 acfe88aac94296abfb3ae23cb65a4cf5 799 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 160 176 4.1E-23 T 13-09-2016 THL1_RS18600 acfe88aac94296abfb3ae23cb65a4cf5 799 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 188 202 4.1E-23 T 13-09-2016 THL1_RS18600 acfe88aac94296abfb3ae23cb65a4cf5 799 Pfam PF02384 N-6 DNA Methylase 137 450 1.1E-104 T 13-09-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THL1_RS18600 acfe88aac94296abfb3ae23cb65a4cf5 799 Gene3D G3DSA:3.40.50.150 138 357 1.4E-36 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS18600 acfe88aac94296abfb3ae23cb65a4cf5 799 Pfam PF12161 HsdM N-terminal domain 8 122 3.8E-17 T 13-09-2016 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THL1_RS18600 acfe88aac94296abfb3ae23cb65a4cf5 799 PANTHER PTHR30408 138 467 9.9E-104 T 13-09-2016 THL1_RS18600 acfe88aac94296abfb3ae23cb65a4cf5 799 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 88 456 7.6E-75 T 13-09-2016 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 THL1_RS18600 acfe88aac94296abfb3ae23cb65a4cf5 799 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 267 273 - T 13-09-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THL1_RS18600 acfe88aac94296abfb3ae23cb65a4cf5 799 PANTHER PTHR30408:SF4 138 467 9.9E-104 T 13-09-2016 THL1_RS15705 6d70daeb8d93c4a6365389323b646064 505 TIGRFAM TIGR02279 PaaC-3OHAcCoADH: 3-hydroxyacyl-CoA dehydrogenase PaaC 5 503 2.9E-247 T 13-09-2016 IPR011967 3-hydroxyacyl-CoA dehydrogenase PaaC GO:0008691|GO:0010124 KEGG: 00040+1.1.1.-|KEGG: 00051+1.1.1.-|KEGG: 00140+1.1.1.-|KEGG: 00240+1.1.1.-|KEGG: 00253+1.1.1.-|KEGG: 00362+1.1.1.-|KEGG: 00363+1.1.1.-|KEGG: 00365+1.1.1.-|KEGG: 00400+1.1.1.-|KEGG: 00520+1.1.1.-|KEGG: 00523+1.1.1.-|KEGG: 00591+1.1.1.-|KEGG: 00622+1.1.1.-|KEGG: 00625+1.1.1.-|KEGG: 00633+1.1.1.-|KEGG: 00640+1.1.1.-|KEGG: 00650+1.1.1.-|KEGG: 00680+1.1.1.-|KEGG: 00720+1.1.1.-|KEGG: 00750+1.1.1.-|KEGG: 00830+1.1.1.-|KEGG: 00950+1.1.1.-|KEGG: 00966+1.1.1.-|KEGG: 00981+1.1.1.-|UniPathway: UPA00930 THL1_RS15705 6d70daeb8d93c4a6365389323b646064 505 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 10 186 2.6E-60 T 13-09-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS15705 6d70daeb8d93c4a6365389323b646064 505 SUPERFAMILY SSF48179 416 501 4.68E-19 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS15705 6d70daeb8d93c4a6365389323b646064 505 PANTHER PTHR23309 394 505 1.0E-184 T 13-09-2016 THL1_RS15705 6d70daeb8d93c4a6365389323b646064 505 PANTHER PTHR23309 7 306 1.0E-184 T 13-09-2016 THL1_RS15705 6d70daeb8d93c4a6365389323b646064 505 SUPERFAMILY SSF51735 8 189 4.06E-54 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS15705 6d70daeb8d93c4a6365389323b646064 505 SUPERFAMILY SSF48179 189 296 1.62E-28 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS15705 6d70daeb8d93c4a6365389323b646064 505 PANTHER PTHR23309:SF12 394 505 1.0E-184 T 13-09-2016 THL1_RS15705 6d70daeb8d93c4a6365389323b646064 505 PANTHER PTHR23309:SF12 7 306 1.0E-184 T 13-09-2016 THL1_RS15705 6d70daeb8d93c4a6365389323b646064 505 Gene3D G3DSA:1.10.1040.10 418 495 3.2E-18 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS15705 6d70daeb8d93c4a6365389323b646064 505 Gene3D G3DSA:1.10.1040.10 192 287 1.3E-27 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS15705 6d70daeb8d93c4a6365389323b646064 505 Gene3D G3DSA:3.40.50.720 6 191 1.5E-56 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS15705 6d70daeb8d93c4a6365389323b646064 505 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 287 4.5E-29 T 13-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS15705 6d70daeb8d93c4a6365389323b646064 505 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 419 502 1.1E-14 T 13-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS15705 6d70daeb8d93c4a6365389323b646064 505 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 187 211 - T 13-09-2016 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS14380 0692c9050c0d4be4b19039725d3cef64 449 PANTHER PTHR24064 13 439 1.6E-194 T 13-09-2016 THL1_RS14380 0692c9050c0d4be4b19039725d3cef64 449 ProSitePatterns PS00217 Sugar transport proteins signature 2. 127 152 - T 13-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 THL1_RS14380 0692c9050c0d4be4b19039725d3cef64 449 SUPERFAMILY SSF103473 6 438 7.19E-78 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS14380 0692c9050c0d4be4b19039725d3cef64 449 TIGRFAM TIGR00895 2A0115: MFS transporter, aromatic acid:H+ symporter (AAHS) family 14 413 1.9E-151 T 13-09-2016 IPR004746 Major facilitator superfamily, aromatic acid:H+ symporter family GO:0005215|GO:0006810|GO:0016021 THL1_RS14380 0692c9050c0d4be4b19039725d3cef64 449 Gene3D G3DSA:1.20.1250.20 28 210 3.8E-38 T 13-09-2016 THL1_RS14380 0692c9050c0d4be4b19039725d3cef64 449 Gene3D G3DSA:1.20.1250.20 265 436 1.7E-23 T 13-09-2016 THL1_RS14380 0692c9050c0d4be4b19039725d3cef64 449 ProSitePatterns PS00216 Sugar transport proteins signature 1. 85 101 - T 13-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 THL1_RS14380 0692c9050c0d4be4b19039725d3cef64 449 Pfam PF07690 Major Facilitator Superfamily 36 406 1.1E-44 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS14380 0692c9050c0d4be4b19039725d3cef64 449 PANTHER PTHR24064:SF234 13 439 1.6E-194 T 13-09-2016 THL1_RS03705 ae885e4fe1a85a254df8d65cb3dd9169 208 PANTHER PTHR32439 4 203 2.2E-75 T 13-09-2016 THL1_RS03705 ae885e4fe1a85a254df8d65cb3dd9169 208 Gene3D G3DSA:3.40.50.10230 1 204 7.1E-83 T 13-09-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 THL1_RS03705 ae885e4fe1a85a254df8d65cb3dd9169 208 Pfam PF02570 Precorrin-8X methylmutase 10 205 3.5E-74 T 13-09-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 THL1_RS03705 ae885e4fe1a85a254df8d65cb3dd9169 208 SUPERFAMILY SSF63965 2 205 4.58E-76 T 13-09-2016 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 THL1_RS27140 a528cfe94e502a7ab74aa1dcc6969781 243 Gene3D G3DSA:3.40.50.2300 10 130 1.0E-43 T 13-09-2016 THL1_RS27140 a528cfe94e502a7ab74aa1dcc6969781 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 166 237 3.7E-22 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS27140 a528cfe94e502a7ab74aa1dcc6969781 243 SUPERFAMILY SSF52172 6 132 5.83E-43 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS27140 a528cfe94e502a7ab74aa1dcc6969781 243 PANTHER PTHR26402:SF292 10 240 3.4E-107 T 13-09-2016 THL1_RS27140 a528cfe94e502a7ab74aa1dcc6969781 243 SMART SM00448 10 121 4.3E-44 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS27140 a528cfe94e502a7ab74aa1dcc6969781 243 SUPERFAMILY SSF46894 138 239 3.68E-25 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS27140 a528cfe94e502a7ab74aa1dcc6969781 243 Gene3D G3DSA:1.10.10.10 138 240 3.1E-30 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS27140 a528cfe94e502a7ab74aa1dcc6969781 243 PANTHER PTHR26402 10 240 3.4E-107 T 13-09-2016 THL1_RS27140 a528cfe94e502a7ab74aa1dcc6969781 243 Pfam PF00072 Response regulator receiver domain 12 122 7.2E-31 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS27140 a528cfe94e502a7ab74aa1dcc6969781 243 SMART SM00862 160 237 1.4E-23 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS10300 65ce12779715ec6517acadcb615a9cad 546 PANTHER PTHR40940:SF1 7 546 7.5E-95 T 13-09-2016 THL1_RS10300 65ce12779715ec6517acadcb615a9cad 546 Pfam PF13584 Oxygen tolerance 12 463 2.1E-112 T 13-09-2016 IPR025738 Aerotolerance-related protein BatD THL1_RS10300 65ce12779715ec6517acadcb615a9cad 546 PANTHER PTHR40940 7 546 7.5E-95 T 13-09-2016 THL1_RS04530 cd03132394ba23b0b879b91f3914dd19 381 SUPERFAMILY SSF53850 59 362 1.04E-72 T 13-09-2016 THL1_RS04530 cd03132394ba23b0b879b91f3914dd19 381 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 18 51 1.5E-4 T 13-09-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THL1_RS04530 cd03132394ba23b0b879b91f3914dd19 381 PIRSF PIRSF019574 26 380 1.4E-76 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS04530 cd03132394ba23b0b879b91f3914dd19 381 PANTHER PTHR30222:SF5 14 359 1.3E-58 T 13-09-2016 THL1_RS04530 cd03132394ba23b0b879b91f3914dd19 381 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 327 353 2.5E-29 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS04530 cd03132394ba23b0b879b91f3914dd19 381 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 282 301 2.5E-29 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS04530 cd03132394ba23b0b879b91f3914dd19 381 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 156 172 2.5E-29 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS04530 cd03132394ba23b0b879b91f3914dd19 381 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 123 136 2.5E-29 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS04530 cd03132394ba23b0b879b91f3914dd19 381 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 202 221 2.5E-29 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS04530 cd03132394ba23b0b879b91f3914dd19 381 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 107 121 2.5E-29 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS04530 cd03132394ba23b0b879b91f3914dd19 381 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 80 101 2.5E-29 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS04530 cd03132394ba23b0b879b91f3914dd19 381 Pfam PF13416 Bacterial extracellular solute-binding protein 76 330 1.1E-32 T 13-09-2016 THL1_RS04530 cd03132394ba23b0b879b91f3914dd19 381 PANTHER PTHR30222 14 359 1.3E-58 T 13-09-2016 THL1_RS04530 cd03132394ba23b0b879b91f3914dd19 381 Gene3D G3DSA:3.40.190.10 60 165 6.5E-38 T 13-09-2016 THL1_RS04530 cd03132394ba23b0b879b91f3914dd19 381 Gene3D G3DSA:3.40.190.10 306 346 6.5E-38 T 13-09-2016 THL1_RS04530 cd03132394ba23b0b879b91f3914dd19 381 Gene3D G3DSA:3.40.190.10 166 305 1.0E-38 T 13-09-2016 THL1_RS27510 c9883af9cc47a727b9403873aea1d4b2 298 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 5 88 1.6E-23 T 13-09-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THL1_RS27510 c9883af9cc47a727b9403873aea1d4b2 298 Pfam PF00589 Phage integrase family 111 277 6.1E-44 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS27510 c9883af9cc47a727b9403873aea1d4b2 298 Gene3D G3DSA:1.10.443.10 109 284 3.0E-52 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS27510 c9883af9cc47a727b9403873aea1d4b2 298 Gene3D G3DSA:1.10.150.130 2 97 6.1E-29 T 13-09-2016 IPR023109 Integrase/recombinase, N-terminal THL1_RS27510 c9883af9cc47a727b9403873aea1d4b2 298 SUPERFAMILY SSF47823 4 96 3.92E-18 T 13-09-2016 IPR010998 Integrase, Lambda-type, N-terminal THL1_RS27510 c9883af9cc47a727b9403873aea1d4b2 298 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 1 291 35.977 T 13-09-2016 IPR023009 Tyrosine recombinase XerC/XerD THL1_RS27510 c9883af9cc47a727b9403873aea1d4b2 298 SUPERFAMILY SSF56349 105 289 4.71E-52 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS27510 c9883af9cc47a727b9403873aea1d4b2 298 PANTHER PTHR30349:SF17 1 298 3.9E-145 T 13-09-2016 THL1_RS27510 c9883af9cc47a727b9403873aea1d4b2 298 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 7 293 3.4E-109 T 13-09-2016 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 THL1_RS27510 c9883af9cc47a727b9403873aea1d4b2 298 PANTHER PTHR30349 1 298 3.9E-145 T 13-09-2016 THL1_RS08740 2742e8e9cc364efef05fc74d487dc399 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.1E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08740 2742e8e9cc364efef05fc74d487dc399 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.1E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08740 2742e8e9cc364efef05fc74d487dc399 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.1E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08740 2742e8e9cc364efef05fc74d487dc399 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.7E-33 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08740 2742e8e9cc364efef05fc74d487dc399 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.7E-33 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08740 2742e8e9cc364efef05fc74d487dc399 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.7E-33 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08740 2742e8e9cc364efef05fc74d487dc399 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.7E-33 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08740 2742e8e9cc364efef05fc74d487dc399 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.7E-33 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08740 2742e8e9cc364efef05fc74d487dc399 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.7E-33 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08740 2742e8e9cc364efef05fc74d487dc399 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 250 1.1E-54 T 13-09-2016 THL1_RS08740 2742e8e9cc364efef05fc74d487dc399 252 PANTHER PTHR24322 157 188 2.7E-39 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08740 2742e8e9cc364efef05fc74d487dc399 252 PANTHER PTHR24322 8 141 2.7E-39 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08740 2742e8e9cc364efef05fc74d487dc399 252 Gene3D G3DSA:3.40.50.720 2 251 3.0E-74 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS08740 2742e8e9cc364efef05fc74d487dc399 252 SUPERFAMILY SSF51735 4 251 6.26E-70 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS00940 fb739059719083ca8cef580e00514413 368 Hamap MF_01841 Agmatine deiminase [aguA]. 6 364 62.317 T 13-09-2016 IPR017754 Agmatine deiminase GO:0009446|GO:0047632 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 THL1_RS00940 fb739059719083ca8cef580e00514413 368 SUPERFAMILY SSF55909 3 364 2.14E-145 T 13-09-2016 THL1_RS00940 fb739059719083ca8cef580e00514413 368 PANTHER PTHR31377:SF2 1 368 3.4E-192 T 13-09-2016 THL1_RS00940 fb739059719083ca8cef580e00514413 368 TIGRFAM TIGR03380 agmatine_aguA: agmatine deiminase 7 364 4.3E-179 T 13-09-2016 IPR017754 Agmatine deiminase GO:0009446|GO:0047632 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 THL1_RS00940 fb739059719083ca8cef580e00514413 368 Gene3D G3DSA:3.75.10.10 4 364 9.1E-156 T 13-09-2016 THL1_RS00940 fb739059719083ca8cef580e00514413 368 PANTHER PTHR31377 1 368 3.4E-192 T 13-09-2016 THL1_RS00940 fb739059719083ca8cef580e00514413 368 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 14 363 5.6E-129 T 13-09-2016 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 THL1_RS13965 656ad75379b882b24942691e138ac89b 288 PANTHER PTHR21471 1 288 1.1E-49 T 13-09-2016 THL1_RS13965 656ad75379b882b24942691e138ac89b 288 SUPERFAMILY SSF55729 6 267 5.99E-31 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS13965 656ad75379b882b24942691e138ac89b 288 PANTHER PTHR21471:SF52 1 288 1.1E-49 T 13-09-2016 THL1_RS13965 656ad75379b882b24942691e138ac89b 288 Gene3D G3DSA:3.40.630.30 5 128 2.0E-12 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS13965 656ad75379b882b24942691e138ac89b 288 Pfam PF00583 Acetyltransferase (GNAT) family 49 101 1.9E-5 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS07690 6e91d439049218c5cad2de51a25011ce 229 Gene3D G3DSA:3.40.50.300 1 224 7.5E-57 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07690 6e91d439049218c5cad2de51a25011ce 229 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS07690 6e91d439049218c5cad2de51a25011ce 229 PANTHER PTHR24220 3 229 8.9E-94 T 13-09-2016 THL1_RS07690 6e91d439049218c5cad2de51a25011ce 229 SMART SM00382 26 206 6.8E-11 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS07690 6e91d439049218c5cad2de51a25011ce 229 SUPERFAMILY SSF52540 2 222 1.21E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07690 6e91d439049218c5cad2de51a25011ce 229 PANTHER PTHR24220:SF568 3 229 8.9E-94 T 13-09-2016 THL1_RS07690 6e91d439049218c5cad2de51a25011ce 229 Pfam PF00005 ABC transporter 19 157 2.8E-28 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS19690 3974526f636195c3d5374a27a5db7a5f 261 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 183 256 2.5E-25 T 13-09-2016 IPR010930 Flagellar basal-body/hook protein, C-terminal domain THL1_RS19690 3974526f636195c3d5374a27a5db7a5f 261 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 13-09-2016 IPR019776 Flagellar basal body rod protein, conserved site THL1_RS19690 3974526f636195c3d5374a27a5db7a5f 261 PANTHER PTHR30435 1 261 2.6E-130 T 13-09-2016 THL1_RS19690 3974526f636195c3d5374a27a5db7a5f 261 PANTHER PTHR30435:SF19 1 261 2.6E-130 T 13-09-2016 THL1_RS19690 3974526f636195c3d5374a27a5db7a5f 261 Pfam PF00460 Flagella basal body rod protein 5 35 9.3E-11 T 13-09-2016 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 THL1_RS19690 3974526f636195c3d5374a27a5db7a5f 261 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 136 6.8E-50 T 13-09-2016 IPR020013 Fagellar hook-basal body protein, FlgE/F/G THL1_RS19690 3974526f636195c3d5374a27a5db7a5f 261 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 148 243 1.2E-29 T 13-09-2016 IPR020013 Fagellar hook-basal body protein, FlgE/F/G THL1_RS19690 3974526f636195c3d5374a27a5db7a5f 261 SUPERFAMILY SSF117143 92 222 2.88E-35 T 13-09-2016 THL1_RS19690 3974526f636195c3d5374a27a5db7a5f 261 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 260 1.4E-114 T 13-09-2016 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 THL1_RS19660 c5e0ab3d7358fce42eb6e873e17f99e8 508 PANTHER PTHR30244:SF1 2 181 1.1E-131 T 13-09-2016 THL1_RS19660 c5e0ab3d7358fce42eb6e873e17f99e8 508 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 1.7E-43 T 13-09-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 THL1_RS19660 c5e0ab3d7358fce42eb6e873e17f99e8 508 SUPERFAMILY SSF64518 1 508 2.09E-105 T 13-09-2016 THL1_RS19660 c5e0ab3d7358fce42eb6e873e17f99e8 508 PRINTS PR00207 Flagellin signature 111 134 6.5E-25 T 13-09-2016 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 THL1_RS19660 c5e0ab3d7358fce42eb6e873e17f99e8 508 PRINTS PR00207 Flagellin signature 76 95 6.5E-25 T 13-09-2016 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 THL1_RS19660 c5e0ab3d7358fce42eb6e873e17f99e8 508 PRINTS PR00207 Flagellin signature 37 54 6.5E-25 T 13-09-2016 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 THL1_RS19660 c5e0ab3d7358fce42eb6e873e17f99e8 508 PANTHER PTHR30244 2 181 1.1E-131 T 13-09-2016 THL1_RS19660 c5e0ab3d7358fce42eb6e873e17f99e8 508 Pfam PF07196 Flagellin hook IN motif 204 251 2.0E-5 T 13-09-2016 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 THL1_RS19660 c5e0ab3d7358fce42eb6e873e17f99e8 508 Pfam PF07196 Flagellin hook IN motif 261 317 7.7E-7 T 13-09-2016 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 THL1_RS19660 c5e0ab3d7358fce42eb6e873e17f99e8 508 PANTHER PTHR30244:SF1 334 508 1.1E-131 T 13-09-2016 THL1_RS19660 c5e0ab3d7358fce42eb6e873e17f99e8 508 PANTHER PTHR30244 334 508 1.1E-131 T 13-09-2016 THL1_RS19660 c5e0ab3d7358fce42eb6e873e17f99e8 508 Pfam PF00700 Bacterial flagellin C-terminal helical region 422 507 2.2E-28 T 13-09-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 THL1_RS19660 c5e0ab3d7358fce42eb6e873e17f99e8 508 Gene3D G3DSA:1.20.1330.10 410 464 1.0E-56 T 13-09-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 THL1_RS19660 c5e0ab3d7358fce42eb6e873e17f99e8 508 Gene3D G3DSA:1.20.1330.10 54 171 1.0E-56 T 13-09-2016 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 THL1_RS01335 496ad575303fa8b835da04b7c34ba080 793 SUPERFAMILY SSF56235 39 791 6.69E-219 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS01335 496ad575303fa8b835da04b7c34ba080 793 PANTHER PTHR34218:SF1 1 793 0.0 T 13-09-2016 THL1_RS01335 496ad575303fa8b835da04b7c34ba080 793 Gene3D G3DSA:2.30.120.10 322 390 8.1E-25 T 13-09-2016 THL1_RS01335 496ad575303fa8b835da04b7c34ba080 793 PANTHER PTHR34218 1 793 0.0 T 13-09-2016 THL1_RS01335 496ad575303fa8b835da04b7c34ba080 793 PIRSF PIRSF001227 1 791 1.3E-168 T 13-09-2016 IPR014395 Penicillin acylase GO:0016811 THL1_RS01335 496ad575303fa8b835da04b7c34ba080 793 Gene3D G3DSA:1.10.439.10 29 197 4.3E-53 T 13-09-2016 IPR023343 Penicillin amidase type, domain1 GO:0016811 THL1_RS01335 496ad575303fa8b835da04b7c34ba080 793 Gene3D G3DSA:3.60.20.10 246 321 2.5E-89 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS01335 496ad575303fa8b835da04b7c34ba080 793 Gene3D G3DSA:3.60.20.10 401 635 2.5E-89 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS01335 496ad575303fa8b835da04b7c34ba080 793 Pfam PF01804 Penicillin amidase 42 780 5.2E-208 T 13-09-2016 IPR002692 Penicillin/cephalosporin acylase GO:0016787|GO:0017000 THL1_RS20055 6a3893d6c9392a42100aa922f56c57df 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 453 4.5E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS20055 6a3893d6c9392a42100aa922f56c57df 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 4.5E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS20055 6a3893d6c9392a42100aa922f56c57df 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 414 4.5E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS20055 6a3893d6c9392a42100aa922f56c57df 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 434 4.5E-13 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS20055 6a3893d6c9392a42100aa922f56c57df 458 SUPERFAMILY SSF55874 292 454 3.93E-37 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS20055 6a3893d6c9392a42100aa922f56c57df 458 Gene3D G3DSA:1.10.287.130 229 298 9.5E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS20055 6a3893d6c9392a42100aa922f56c57df 458 SUPERFAMILY SSF47384 221 300 3.73E-15 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS20055 6a3893d6c9392a42100aa922f56c57df 458 Gene3D G3DSA:3.30.565.10 308 454 8.1E-35 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS20055 6a3893d6c9392a42100aa922f56c57df 458 SMART SM00387 348 456 7.2E-27 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS20055 6a3893d6c9392a42100aa922f56c57df 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 355 454 5.3E-17 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS20055 6a3893d6c9392a42100aa922f56c57df 458 SMART SM00388 237 302 9.4E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS20055 6a3893d6c9392a42100aa922f56c57df 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 300 8.4E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS20055 6a3893d6c9392a42100aa922f56c57df 458 PANTHER PTHR24423 178 458 3.7E-68 T 13-09-2016 THL1_RS20055 6a3893d6c9392a42100aa922f56c57df 458 PANTHER PTHR24423 125 151 3.7E-68 T 13-09-2016 THL1_RS20055 6a3893d6c9392a42100aa922f56c57df 458 Pfam PF08521 Two-component sensor kinase N-terminal 16 160 4.0E-12 T 13-09-2016 IPR013727 Two-component sensor kinase, N-terminal THL1_RS20055 6a3893d6c9392a42100aa922f56c57df 458 PANTHER PTHR24423:SF474 178 458 3.7E-68 T 13-09-2016 THL1_RS20055 6a3893d6c9392a42100aa922f56c57df 458 PANTHER PTHR24423:SF474 125 151 3.7E-68 T 13-09-2016 THL1_RS26610 b0ec7ea93bc682ddef653a3ba820cbdc 304 PANTHER PTHR30503 2 303 1.5E-98 T 13-09-2016 THL1_RS26610 b0ec7ea93bc682ddef653a3ba820cbdc 304 Pfam PF05661 Protein of unknown function (DUF808) 4 289 1.9E-115 T 13-09-2016 IPR008526 Inner membrane protein YedI THL1_RS26610 b0ec7ea93bc682ddef653a3ba820cbdc 304 PIRSF PIRSF016660 1 303 1.3E-119 T 13-09-2016 IPR008526 Inner membrane protein YedI THL1_RS00155 c58d18c6354c6c791f11db138c744f1c 317 PANTHER PTHR30537 3 316 2.1E-127 T 13-09-2016 THL1_RS00155 c58d18c6354c6c791f11db138c744f1c 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 69 1.3E-21 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS00155 c58d18c6354c6c791f11db138c744f1c 317 SUPERFAMILY SSF53850 97 303 1.28E-40 T 13-09-2016 THL1_RS00155 c58d18c6354c6c791f11db138c744f1c 317 SUPERFAMILY SSF46785 8 88 1.18E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00155 c58d18c6354c6c791f11db138c744f1c 317 TIGRFAM TIGR03418 chol_sulf_TF: putative choline sulfate-utilization transcription factor 8 298 3.6E-129 T 13-09-2016 IPR017786 Transcription factor, choline sulphate-utilisation, putative THL1_RS00155 c58d18c6354c6c791f11db138c744f1c 317 Gene3D G3DSA:1.10.10.10 7 87 4.2E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00155 c58d18c6354c6c791f11db138c744f1c 317 PANTHER PTHR30537:SF22 3 316 2.1E-127 T 13-09-2016 THL1_RS00155 c58d18c6354c6c791f11db138c744f1c 317 Gene3D G3DSA:3.40.190.10 97 196 6.9E-30 T 13-09-2016 THL1_RS00155 c58d18c6354c6c791f11db138c744f1c 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 9.7E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS00155 c58d18c6354c6c791f11db138c744f1c 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 9.7E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS00155 c58d18c6354c6c791f11db138c744f1c 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 9.7E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS00155 c58d18c6354c6c791f11db138c744f1c 317 Pfam PF03466 LysR substrate binding domain 94 299 7.7E-38 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS06760 1f0470a66f33f846ff94c1ebc37cf5c1 195 PANTHER PTHR30390:SF6 1 194 1.4E-78 T 13-09-2016 THL1_RS06760 1f0470a66f33f846ff94c1ebc37cf5c1 195 TIGRFAM TIGR00441 gmhA: phosphoheptose isomerase 34 186 3.4E-65 T 13-09-2016 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478|UniPathway: UPA00041 THL1_RS06760 1f0470a66f33f846ff94c1ebc37cf5c1 195 SUPERFAMILY SSF53697 4 189 8.04E-50 T 13-09-2016 THL1_RS06760 1f0470a66f33f846ff94c1ebc37cf5c1 195 Pfam PF13580 SIS domain 23 145 3.5E-30 T 13-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 THL1_RS06760 1f0470a66f33f846ff94c1ebc37cf5c1 195 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 1 189 34.207 T 13-09-2016 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478|UniPathway: UPA00041 THL1_RS06760 1f0470a66f33f846ff94c1ebc37cf5c1 195 Gene3D G3DSA:3.40.50.10490 4 189 3.1E-58 T 13-09-2016 THL1_RS06760 1f0470a66f33f846ff94c1ebc37cf5c1 195 PANTHER PTHR30390 1 194 1.4E-78 T 13-09-2016 THL1_RS10955 deee158cc1e1d9e6177cf56f7f483127 139 PANTHER PTHR39624 1 134 1.2E-26 T 13-09-2016 THL1_RS10955 deee158cc1e1d9e6177cf56f7f483127 139 PANTHER PTHR39624:SF2 1 134 1.2E-26 T 13-09-2016 THL1_RS10955 deee158cc1e1d9e6177cf56f7f483127 139 SUPERFAMILY SSF82784 7 130 3.4E-29 T 13-09-2016 IPR003718 OsmC/Ohr family THL1_RS10955 deee158cc1e1d9e6177cf56f7f483127 139 Pfam PF02566 OsmC-like protein 36 128 2.0E-17 T 13-09-2016 IPR003718 OsmC/Ohr family THL1_RS10955 deee158cc1e1d9e6177cf56f7f483127 139 Gene3D G3DSA:3.30.300.20 8 131 7.5E-33 T 13-09-2016 IPR015946 K homology domain-like, alpha/beta THL1_RS08155 57a64968ee4386edef57c2115024afb5 230 SUPERFAMILY SSF103088 107 228 1.96E-37 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS08155 57a64968ee4386edef57c2115024afb5 230 PANTHER PTHR30128 102 228 5.4E-47 T 13-09-2016 THL1_RS08155 57a64968ee4386edef57c2115024afb5 230 Gene3D G3DSA:3.30.1330.60 114 228 7.1E-41 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS08155 57a64968ee4386edef57c2115024afb5 230 Pfam PF00691 OmpA family 125 222 5.2E-26 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS08155 57a64968ee4386edef57c2115024afb5 230 PRINTS PR01021 OMPA domain signature 157 172 4.2E-20 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS08155 57a64968ee4386edef57c2115024afb5 230 PRINTS PR01021 OMPA domain signature 126 148 4.2E-20 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS08155 57a64968ee4386edef57c2115024afb5 230 PRINTS PR01021 OMPA domain signature 172 188 4.2E-20 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS08155 57a64968ee4386edef57c2115024afb5 230 SUPERFAMILY SSF103647 70 101 1.83E-8 T 13-09-2016 IPR028974 TSP type-3 repeat GO:0005509 THL1_RS08155 57a64968ee4386edef57c2115024afb5 230 Gene3D G3DSA:4.10.1080.10 72 101 9.0E-5 T 13-09-2016 IPR028974 TSP type-3 repeat GO:0005509 THL1_RS19710 7a5581acee464c3710345899c1a43b53 227 Pfam PF13861 FlgD Tudor-like domain 87 223 2.9E-18 T 13-09-2016 IPR025963 FlgD Tudor-like domain THL1_RS19710 7a5581acee464c3710345899c1a43b53 227 Pfam PF13860 FlgD Ig-like domain 109 181 6.8E-23 T 13-09-2016 IPR025965 FlgD Ig-like domain THL1_RS19710 7a5581acee464c3710345899c1a43b53 227 PANTHER PTHR30435 22 213 6.7E-67 T 13-09-2016 THL1_RS19710 7a5581acee464c3710345899c1a43b53 227 PANTHER PTHR30435:SF15 22 213 6.7E-67 T 13-09-2016 THL1_RS19710 7a5581acee464c3710345899c1a43b53 227 Pfam PF03963 Flagellar hook capping protein - N-terminal region 13 79 9.5E-24 T 13-09-2016 IPR005648 Flagellar hook capping protein THL1_RS06775 cfcddc88c05782e84198815c6bfd5639 211 Pfam PF00849 RNA pseudouridylate synthase 15 161 5.7E-30 T 13-09-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS06775 cfcddc88c05782e84198815c6bfd5639 211 SUPERFAMILY SSF55120 5 210 5.76E-61 T 13-09-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS06775 cfcddc88c05782e84198815c6bfd5639 211 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 53 67 - T 13-09-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS06775 cfcddc88c05782e84198815c6bfd5639 211 PANTHER PTHR11079 5 210 1.0E-63 T 13-09-2016 THL1_RS06775 cfcddc88c05782e84198815c6bfd5639 211 PANTHER PTHR11079:SF86 5 210 1.0E-63 T 13-09-2016 THL1_RS04840 cf31d0ce10f4906f80db8151e9aadb67 154 PIRSF PIRSF003174 1 153 3.6E-68 T 13-09-2016 IPR010292 Uncharacterised protein family CreA THL1_RS04840 cf31d0ce10f4906f80db8151e9aadb67 154 PANTHER PTHR37952 4 150 3.6E-75 T 13-09-2016 THL1_RS04840 cf31d0ce10f4906f80db8151e9aadb67 154 PANTHER PTHR37952:SF2 4 150 3.6E-75 T 13-09-2016 THL1_RS04840 cf31d0ce10f4906f80db8151e9aadb67 154 Pfam PF05981 CreA protein 23 150 1.2E-57 T 13-09-2016 IPR010292 Uncharacterised protein family CreA THL1_RS08215 109d812caa71737dca539ec25204e5e7 111 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 104 1.3E-25 T 13-09-2016 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 THL1_RS08215 109d812caa71737dca539ec25204e5e7 111 PANTHER PTHR34583:SF1 1 108 4.1E-57 T 13-09-2016 THL1_RS08215 109d812caa71737dca539ec25204e5e7 111 PANTHER PTHR34583 1 108 4.1E-57 T 13-09-2016 THL1_RS17165 c4109834268f02fb2fe8a5472126383c 498 PANTHER PTHR10742 48 498 8.1E-74 T 13-09-2016 THL1_RS17165 c4109834268f02fb2fe8a5472126383c 498 PRINTS PR00757 Flavin-containing amine oxidase signature 442 464 1.5E-21 T 13-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 THL1_RS17165 c4109834268f02fb2fe8a5472126383c 498 PRINTS PR00757 Flavin-containing amine oxidase signature 244 266 1.5E-21 T 13-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 THL1_RS17165 c4109834268f02fb2fe8a5472126383c 498 PRINTS PR00757 Flavin-containing amine oxidase signature 473 490 1.5E-21 T 13-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 THL1_RS17165 c4109834268f02fb2fe8a5472126383c 498 PRINTS PR00757 Flavin-containing amine oxidase signature 342 361 1.5E-21 T 13-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 THL1_RS17165 c4109834268f02fb2fe8a5472126383c 498 PRINTS PR00757 Flavin-containing amine oxidase signature 58 77 1.5E-21 T 13-09-2016 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 THL1_RS17165 c4109834268f02fb2fe8a5472126383c 498 SUPERFAMILY SSF51905 455 495 7.12E-57 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS17165 c4109834268f02fb2fe8a5472126383c 498 SUPERFAMILY SSF51905 58 356 7.12E-57 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS17165 c4109834268f02fb2fe8a5472126383c 498 Gene3D G3DSA:3.50.50.60 54 138 1.9E-47 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS17165 c4109834268f02fb2fe8a5472126383c 498 Gene3D G3DSA:3.50.50.60 256 355 1.9E-47 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS17165 c4109834268f02fb2fe8a5472126383c 498 Gene3D G3DSA:3.50.50.60 451 495 1.9E-47 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS17165 c4109834268f02fb2fe8a5472126383c 498 PANTHER PTHR10742:SF216 48 498 8.1E-74 T 13-09-2016 THL1_RS17165 c4109834268f02fb2fe8a5472126383c 498 Gene3D G3DSA:1.10.405.10 164 240 2.9E-18 T 13-09-2016 THL1_RS17165 c4109834268f02fb2fe8a5472126383c 498 SUPERFAMILY SSF54373 341 442 2.94E-23 T 13-09-2016 THL1_RS17165 c4109834268f02fb2fe8a5472126383c 498 Pfam PF01593 Flavin containing amine oxidoreductase 66 488 1.1E-48 T 13-09-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 THL1_RS03015 caab148310cb1572c4140bd656ccb806 746 PANTHER PTHR32309:SF13 1 130 4.1E-158 T 13-09-2016 THL1_RS03015 caab148310cb1572c4140bd656ccb806 746 PANTHER PTHR32309:SF13 147 744 4.1E-158 T 13-09-2016 THL1_RS03015 caab148310cb1572c4140bd656ccb806 746 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 559 725 2.4E-9 T 13-09-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THL1_RS03015 caab148310cb1572c4140bd656ccb806 746 Pfam PF13807 G-rich domain on putative tyrosine kinase 409 480 3.0E-18 T 13-09-2016 IPR032807 Tyrosine kinase, G-rich domain THL1_RS03015 caab148310cb1572c4140bd656ccb806 746 Gene3D G3DSA:3.40.50.300 550 729 2.4E-33 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03015 caab148310cb1572c4140bd656ccb806 746 Pfam PF02706 Chain length determinant protein 22 210 5.1E-22 T 13-09-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 THL1_RS03015 caab148310cb1572c4140bd656ccb806 746 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 531 732 4.1E-48 T 13-09-2016 IPR005702 Exopolysaccharide synthesis protein GO:0045226 THL1_RS03015 caab148310cb1572c4140bd656ccb806 746 PANTHER PTHR32309 1 130 4.1E-158 T 13-09-2016 THL1_RS03015 caab148310cb1572c4140bd656ccb806 746 PANTHER PTHR32309 147 744 4.1E-158 T 13-09-2016 THL1_RS03015 caab148310cb1572c4140bd656ccb806 746 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 20 26 - T 13-09-2016 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|Reactome: REACT_21259|Reactome: REACT_71 THL1_RS03015 caab148310cb1572c4140bd656ccb806 746 SUPERFAMILY SSF52540 550 724 2.75E-34 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06630 866ad540fa3f6b663c610b717ea24a06 104 SUPERFAMILY SSF103481 5 103 6.28E-19 T 13-09-2016 THL1_RS06630 866ad540fa3f6b663c610b717ea24a06 104 PANTHER PTHR30561 1 103 3.5E-48 T 13-09-2016 THL1_RS06630 866ad540fa3f6b663c610b717ea24a06 104 PANTHER PTHR30561:SF0 1 103 3.5E-48 T 13-09-2016 THL1_RS06630 866ad540fa3f6b663c610b717ea24a06 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.1E-29 T 13-09-2016 IPR000390 Small multidrug resistance protein family GO:0016021 THL1_RS27030 e74c9e942a22cf0d16f368f768606bc2 188 SUPERFAMILY SSF55811 5 178 8.26E-36 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS27030 e74c9e942a22cf0d16f368f768606bc2 188 Pfam PF00293 NUDIX domain 48 161 1.1E-15 T 13-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 THL1_RS27030 e74c9e942a22cf0d16f368f768606bc2 188 ProSitePatterns PS00893 Nudix box signature. 80 101 - T 13-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THL1_RS27030 e74c9e942a22cf0d16f368f768606bc2 188 Gene3D G3DSA:3.90.79.10 4 177 4.0E-39 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS27030 e74c9e942a22cf0d16f368f768606bc2 188 PANTHER PTHR11839:SF12 2 186 8.0E-88 T 13-09-2016 THL1_RS27030 e74c9e942a22cf0d16f368f768606bc2 188 PANTHER PTHR11839 2 186 8.0E-88 T 13-09-2016 THL1_RS24215 a134bcbb2f3a6749fc96efc76f1948d3 772 SUPERFAMILY SSF53955 161 357 3.66E-66 T 13-09-2016 IPR023346 Lysozyme-like domain THL1_RS24215 a134bcbb2f3a6749fc96efc76f1948d3 772 PIRSF PIRSF002799 1 772 0.0 T 13-09-2016 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00500+2.4.1.12|KEGG: 00550+3.4.-.-+2.4.1.129|KEGG: 00780+3.4.-.-|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS24215 a134bcbb2f3a6749fc96efc76f1948d3 772 Gene3D G3DSA:3.40.710.10 338 748 2.9E-113 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS24215 a134bcbb2f3a6749fc96efc76f1948d3 772 Gene3D G3DSA:3.30.2060.10 67 154 1.4E-23 T 13-09-2016 THL1_RS24215 a134bcbb2f3a6749fc96efc76f1948d3 772 Pfam PF00905 Penicillin binding protein transpeptidase domain 429 670 7.9E-18 T 13-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THL1_RS24215 a134bcbb2f3a6749fc96efc76f1948d3 772 TIGRFAM TIGR02071 PBP_1b: penicillin-binding protein 1B 24 748 0.0 T 13-09-2016 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00500+2.4.1.12|KEGG: 00550+3.4.-.-+2.4.1.129|KEGG: 00780+3.4.-.-|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS24215 a134bcbb2f3a6749fc96efc76f1948d3 772 PANTHER PTHR32282 151 748 5.4E-262 T 13-09-2016 THL1_RS24215 a134bcbb2f3a6749fc96efc76f1948d3 772 Pfam PF14814 Bifunctional transglycosylase second domain 69 152 4.0E-24 T 13-09-2016 IPR028166 Bifunctional transglycosylase second domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00500+2.4.1.12|KEGG: 00550+3.4.-.-+2.4.1.129|KEGG: 00780+3.4.-.-|MetaCyc: PWY-1001|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS24215 a134bcbb2f3a6749fc96efc76f1948d3 772 Gene3D G3DSA:1.10.3810.10 164 337 1.8E-65 T 13-09-2016 THL1_RS24215 a134bcbb2f3a6749fc96efc76f1948d3 772 PANTHER PTHR32282:SF11 151 748 5.4E-262 T 13-09-2016 THL1_RS24215 a134bcbb2f3a6749fc96efc76f1948d3 772 Gene3D G3DSA:1.20.5.100 12 51 6.1E-8 T 13-09-2016 THL1_RS24215 a134bcbb2f3a6749fc96efc76f1948d3 772 SUPERFAMILY SSF56601 317 339 1.88E-118 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS24215 a134bcbb2f3a6749fc96efc76f1948d3 772 SUPERFAMILY SSF56601 368 754 1.88E-118 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS24215 a134bcbb2f3a6749fc96efc76f1948d3 772 Pfam PF00912 Transglycosylase 164 334 5.5E-58 T 13-09-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 THL1_RS03375 2ef6a6dac0c80666c236da0638f1014a 116 Gene3D G3DSA:2.60.300.12 8 102 2.3E-33 T 13-09-2016 IPR000361 FeS cluster biogenesis THL1_RS03375 2ef6a6dac0c80666c236da0638f1014a 116 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 116 37.427 T 13-09-2016 IPR023063 FeS cluster insertion protein ErpA GO:0016226 THL1_RS03375 2ef6a6dac0c80666c236da0638f1014a 116 PANTHER PTHR10072 10 116 7.7E-50 T 13-09-2016 THL1_RS03375 2ef6a6dac0c80666c236da0638f1014a 116 Pfam PF01521 Iron-sulphur cluster biosynthesis 11 111 1.9E-19 T 13-09-2016 IPR000361 FeS cluster biogenesis THL1_RS03375 2ef6a6dac0c80666c236da0638f1014a 116 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 12 115 2.0E-38 T 13-09-2016 IPR016092 FeS cluster insertion protein GO:0005198|GO:0016226|GO:0051536 THL1_RS03375 2ef6a6dac0c80666c236da0638f1014a 116 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 97 114 - T 13-09-2016 IPR017870 FeS cluster insertion, C-terminal, conserved site THL1_RS03375 2ef6a6dac0c80666c236da0638f1014a 116 SUPERFAMILY SSF89360 5 102 3.34E-32 T 13-09-2016 IPR000361 FeS cluster biogenesis THL1_RS16485 264af4cfa28c433c136efe93b0c278e2 368 SMART SM00922 144 237 1.7E-5 T 13-09-2016 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal THL1_RS16485 264af4cfa28c433c136efe93b0c278e2 368 Pfam PF13378 Enolase C-terminal domain-like 147 355 3.1E-27 T 13-09-2016 IPR029065 Enolase C-terminal domain-like THL1_RS16485 264af4cfa28c433c136efe93b0c278e2 368 Gene3D G3DSA:3.20.20.120 116 350 2.2E-48 T 13-09-2016 IPR029065 Enolase C-terminal domain-like THL1_RS16485 264af4cfa28c433c136efe93b0c278e2 368 SUPERFAMILY SSF54826 1 127 5.46E-24 T 13-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THL1_RS16485 264af4cfa28c433c136efe93b0c278e2 368 SUPERFAMILY SSF51604 126 364 3.8E-40 T 13-09-2016 IPR029065 Enolase C-terminal domain-like THL1_RS16485 264af4cfa28c433c136efe93b0c278e2 368 Gene3D G3DSA:3.30.390.10 1 115 1.5E-32 T 13-09-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THL1_RS16485 264af4cfa28c433c136efe93b0c278e2 368 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 27 126 2.9E-20 T 13-09-2016 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain THL1_RS16485 264af4cfa28c433c136efe93b0c278e2 368 PANTHER PTHR13794 1 359 5.5E-48 T 13-09-2016 IPR001354 Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase GO:0003824|GO:0008152 THL1_RS08750 f4ccddf1c21a1944be7ec3c47892b032 255 PANTHER PTHR13832 3 250 4.8E-39 T 13-09-2016 IPR015655 Protein phosphatase 2C family GO:0004722|GO:0006470 KEGG: 04660+3.1.3.16 THL1_RS08750 f4ccddf1c21a1944be7ec3c47892b032 255 SMART SM00332 2 228 2.3E-12 T 13-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 THL1_RS08750 f4ccddf1c21a1944be7ec3c47892b032 255 Pfam PF13672 Protein phosphatase 2C 18 206 6.4E-11 T 13-09-2016 THL1_RS08750 f4ccddf1c21a1944be7ec3c47892b032 255 Gene3D G3DSA:3.60.40.10 7 229 9.1E-57 T 13-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 THL1_RS08750 f4ccddf1c21a1944be7ec3c47892b032 255 SUPERFAMILY SSF81606 5 228 9.81E-55 T 13-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 THL1_RS08750 f4ccddf1c21a1944be7ec3c47892b032 255 PANTHER PTHR13832:SF278 3 250 4.8E-39 T 13-09-2016 THL1_RS08750 f4ccddf1c21a1944be7ec3c47892b032 255 SMART SM00331 11 230 5.8E-22 T 13-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 THL1_RS01210 a5aa0c0cb40d2d87de85ff0f3a3920c2 284 Pfam PF00140 Sigma-70 factor, region 1.2 17 41 3.0E-4 T 13-09-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS01210 a5aa0c0cb40d2d87de85ff0f3a3920c2 284 Pfam PF04542 Sigma-70 region 2 55 123 5.4E-16 T 13-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS01210 a5aa0c0cb40d2d87de85ff0f3a3920c2 284 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 252 278 - T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS01210 a5aa0c0cb40d2d87de85ff0f3a3920c2 284 Pfam PF04545 Sigma-70, region 4 229 279 1.1E-15 T 13-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS01210 a5aa0c0cb40d2d87de85ff0f3a3920c2 284 PANTHER PTHR30376 3 279 4.1E-115 T 13-09-2016 THL1_RS01210 a5aa0c0cb40d2d87de85ff0f3a3920c2 284 Gene3D G3DSA:1.10.601.10 16 123 1.9E-35 T 13-09-2016 THL1_RS01210 a5aa0c0cb40d2d87de85ff0f3a3920c2 284 PRINTS PR00046 Major sigma-70 factor signature 78 91 5.0E-17 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS01210 a5aa0c0cb40d2d87de85ff0f3a3920c2 284 PRINTS PR00046 Major sigma-70 factor signature 233 245 5.0E-17 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS01210 a5aa0c0cb40d2d87de85ff0f3a3920c2 284 PRINTS PR00046 Major sigma-70 factor signature 252 267 5.0E-17 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS01210 a5aa0c0cb40d2d87de85ff0f3a3920c2 284 PRINTS PR00046 Major sigma-70 factor signature 267 278 5.0E-17 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS01210 a5aa0c0cb40d2d87de85ff0f3a3920c2 284 Gene3D G3DSA:1.10.10.10 225 280 2.4E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS01210 a5aa0c0cb40d2d87de85ff0f3a3920c2 284 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 49 279 1.1E-31 T 13-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS01210 a5aa0c0cb40d2d87de85ff0f3a3920c2 284 SUPERFAMILY SSF88659 198 282 5.79E-18 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS01210 a5aa0c0cb40d2d87de85ff0f3a3920c2 284 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 16 283 4.2E-124 T 13-09-2016 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 THL1_RS01210 a5aa0c0cb40d2d87de85ff0f3a3920c2 284 SUPERFAMILY SSF88946 15 123 1.57E-38 T 13-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS01210 a5aa0c0cb40d2d87de85ff0f3a3920c2 284 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 78 91 - T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS01210 a5aa0c0cb40d2d87de85ff0f3a3920c2 284 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 2 284 53.519 T 13-09-2016 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0008270|GO:0009408|GO:0016987 THL1_RS05525 0480e3403881f0fe2b449c51240ba66e 345 PRINTS PR00069 Aldo-keto reductase signature 116 134 1.1E-6 T 13-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 THL1_RS05525 0480e3403881f0fe2b449c51240ba66e 345 PRINTS PR00069 Aldo-keto reductase signature 163 180 1.1E-6 T 13-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 THL1_RS05525 0480e3403881f0fe2b449c51240ba66e 345 PANTHER PTHR11732 151 345 4.1E-180 T 13-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta THL1_RS05525 0480e3403881f0fe2b449c51240ba66e 345 PANTHER PTHR11732 1 134 4.1E-180 T 13-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta THL1_RS05525 0480e3403881f0fe2b449c51240ba66e 345 Gene3D G3DSA:3.20.20.100 1 342 1.3E-98 T 13-09-2016 IPR023210 NADP-dependent oxidoreductase domain THL1_RS05525 0480e3403881f0fe2b449c51240ba66e 345 SUPERFAMILY SSF51430 1 343 1.03E-103 T 13-09-2016 IPR023210 NADP-dependent oxidoreductase domain THL1_RS05525 0480e3403881f0fe2b449c51240ba66e 345 PANTHER PTHR11732:SF112 151 345 4.1E-180 T 13-09-2016 THL1_RS05525 0480e3403881f0fe2b449c51240ba66e 345 PANTHER PTHR11732:SF112 1 134 4.1E-180 T 13-09-2016 THL1_RS05525 0480e3403881f0fe2b449c51240ba66e 345 Pfam PF00248 Aldo/keto reductase family 16 336 7.4E-64 T 13-09-2016 IPR023210 NADP-dependent oxidoreductase domain THL1_RS22905 1442ba6a629fd6169d7c2ad3cae1649a 229 Pfam PF01584 CheW-like domain 84 222 2.4E-19 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS22905 1442ba6a629fd6169d7c2ad3cae1649a 229 PANTHER PTHR22617 79 216 1.3E-13 T 13-09-2016 THL1_RS22905 1442ba6a629fd6169d7c2ad3cae1649a 229 SMART SM00260 78 221 1.3E-4 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS22905 1442ba6a629fd6169d7c2ad3cae1649a 229 SUPERFAMILY SSF50341 79 223 8.37E-21 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS15070 c8f3e47ed4bf7051a0d99c11140d329c 410 Pfam PF05155 Phage X family 323 407 4.4E-16 T 13-09-2016 IPR022688 Replication-associated protein G2P, C-terminal GO:0006260 THL1_RS15070 c8f3e47ed4bf7051a0d99c11140d329c 410 TIGRFAM TIGR01629 rep_II_X: phage/plasmid replication protein, gene II/X family 3 406 1.3E-84 T 13-09-2016 IPR006516 Replication-associated protein G2P GO:0006260 THL1_RS15070 c8f3e47ed4bf7051a0d99c11140d329c 410 Pfam PF05144 Phage replication protein CRI 2 269 4.9E-55 T 13-09-2016 IPR022686 Replication-associated protein G2P, N-terminal GO:0006260 THL1_RS15025 c8f3e47ed4bf7051a0d99c11140d329c 410 Pfam PF05155 Phage X family 323 407 4.4E-16 T 13-09-2016 IPR022688 Replication-associated protein G2P, C-terminal GO:0006260 THL1_RS15025 c8f3e47ed4bf7051a0d99c11140d329c 410 TIGRFAM TIGR01629 rep_II_X: phage/plasmid replication protein, gene II/X family 3 406 1.3E-84 T 13-09-2016 IPR006516 Replication-associated protein G2P GO:0006260 THL1_RS15025 c8f3e47ed4bf7051a0d99c11140d329c 410 Pfam PF05144 Phage replication protein CRI 2 269 4.9E-55 T 13-09-2016 IPR022686 Replication-associated protein G2P, N-terminal GO:0006260 THL1_RS11110 b12a80227c00739f459b171a4dbba3cd 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 254 4.1E-46 T 13-09-2016 THL1_RS11110 b12a80227c00739f459b171a4dbba3cd 259 SUPERFAMILY SSF51735 11 255 6.06E-63 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11110 b12a80227c00739f459b171a4dbba3cd 259 PANTHER PTHR24322:SF570 14 134 4.3E-46 T 13-09-2016 THL1_RS11110 b12a80227c00739f459b171a4dbba3cd 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.3E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11110 b12a80227c00739f459b171a4dbba3cd 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.3E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11110 b12a80227c00739f459b171a4dbba3cd 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.3E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11110 b12a80227c00739f459b171a4dbba3cd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.2E-33 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11110 b12a80227c00739f459b171a4dbba3cd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.2E-33 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11110 b12a80227c00739f459b171a4dbba3cd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 2.2E-33 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11110 b12a80227c00739f459b171a4dbba3cd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.2E-33 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11110 b12a80227c00739f459b171a4dbba3cd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.2E-33 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11110 b12a80227c00739f459b171a4dbba3cd 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 2.2E-33 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11110 b12a80227c00739f459b171a4dbba3cd 259 PANTHER PTHR24322 14 134 4.3E-46 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11110 b12a80227c00739f459b171a4dbba3cd 259 PANTHER PTHR24322:SF570 151 183 4.3E-46 T 13-09-2016 THL1_RS11110 b12a80227c00739f459b171a4dbba3cd 259 PANTHER PTHR24322 151 183 4.3E-46 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS11110 b12a80227c00739f459b171a4dbba3cd 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS11110 b12a80227c00739f459b171a4dbba3cd 259 Gene3D G3DSA:3.40.50.720 7 255 3.0E-61 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07580 5b7eb6ca28086b5701198bc5b323f432 243 Gene3D G3DSA:1.10.10.10 136 236 1.9E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07580 5b7eb6ca28086b5701198bc5b323f432 243 SMART SM00448 6 119 4.6E-45 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS07580 5b7eb6ca28086b5701198bc5b323f432 243 SUPERFAMILY SSF46894 138 234 1.05E-22 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS07580 5b7eb6ca28086b5701198bc5b323f432 243 SUPERFAMILY SSF52172 4 133 2.85E-44 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS07580 5b7eb6ca28086b5701198bc5b323f432 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 233 4.5E-19 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS07580 5b7eb6ca28086b5701198bc5b323f432 243 Pfam PF00072 Response regulator receiver domain 8 120 1.0E-29 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS07580 5b7eb6ca28086b5701198bc5b323f432 243 PANTHER PTHR26402:SF528 6 240 3.5E-145 T 13-09-2016 THL1_RS07580 5b7eb6ca28086b5701198bc5b323f432 243 Gene3D G3DSA:3.40.50.2300 3 126 1.9E-42 T 13-09-2016 THL1_RS07580 5b7eb6ca28086b5701198bc5b323f432 243 PANTHER PTHR26402 6 240 3.5E-145 T 13-09-2016 THL1_RS07580 5b7eb6ca28086b5701198bc5b323f432 243 SMART SM00862 157 233 4.8E-17 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS18300 d3991c842add00f2749abd4fc3533367 200 Gene3D G3DSA:1.20.1050.10 85 198 3.4E-34 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS18300 d3991c842add00f2749abd4fc3533367 200 Gene3D G3DSA:3.40.30.10 3 84 1.3E-27 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS18300 d3991c842add00f2749abd4fc3533367 200 PANTHER PTHR11260 3 193 1.4E-45 T 13-09-2016 THL1_RS18300 d3991c842add00f2749abd4fc3533367 200 Pfam PF13417 Glutathione S-transferase, N-terminal domain 5 76 2.2E-17 T 13-09-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THL1_RS18300 d3991c842add00f2749abd4fc3533367 200 Pfam PF00043 Glutathione S-transferase, C-terminal domain 120 193 1.8E-12 T 13-09-2016 IPR004046 Glutathione S-transferase, C-terminal THL1_RS18300 d3991c842add00f2749abd4fc3533367 200 SUPERFAMILY SSF47616 77 195 1.81E-30 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS18300 d3991c842add00f2749abd4fc3533367 200 SUPERFAMILY SSF52833 1 76 2.21E-24 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS19265 7cc91a1957a98a0a0580390d598720b9 196 PANTHER PTHR36917 1 188 1.1E-61 T 13-09-2016 THL1_RS19265 7cc91a1957a98a0a0580390d598720b9 196 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 1 189 17.793 T 13-09-2016 IPR006008 Intracellular septation protein A GO:0016021 THL1_RS19265 7cc91a1957a98a0a0580390d598720b9 196 Pfam PF04279 Intracellular septation protein A 1 187 2.3E-58 T 13-09-2016 IPR006008 Intracellular septation protein A GO:0016021 THL1_RS19265 7cc91a1957a98a0a0580390d598720b9 196 PANTHER PTHR36917:SF1 1 188 1.1E-61 T 13-09-2016 THL1_RS19265 7cc91a1957a98a0a0580390d598720b9 196 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 1 186 5.0E-52 T 13-09-2016 IPR006008 Intracellular septation protein A GO:0016021 THL1_RS19265 7cc91a1957a98a0a0580390d598720b9 196 Gene3D G3DSA:1.20.120.80 134 153 1.6E-4 T 13-09-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 THL1_RS19265 7cc91a1957a98a0a0580390d598720b9 196 Gene3D G3DSA:1.20.120.80 5 98 1.6E-4 T 13-09-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 THL1_RS26905 3969481b5714b4909fa4fa515d053289 245 Gene3D G3DSA:1.10.260.40 125 160 5.1E-5 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS00895 7c4bf55eabdfc0b490ef43bfc6b68f3c 260 SUPERFAMILY SSF52540 3 215 5.32E-64 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00895 7c4bf55eabdfc0b490ef43bfc6b68f3c 260 Pfam PF00005 ABC transporter 21 160 5.4E-29 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS00895 7c4bf55eabdfc0b490ef43bfc6b68f3c 260 SMART SM00382 30 209 3.0E-17 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS00895 7c4bf55eabdfc0b490ef43bfc6b68f3c 260 Gene3D G3DSA:3.40.50.300 2 216 1.0E-61 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00895 7c4bf55eabdfc0b490ef43bfc6b68f3c 260 PANTHER PTHR24220 5 208 2.3E-111 T 13-09-2016 THL1_RS00895 7c4bf55eabdfc0b490ef43bfc6b68f3c 260 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS00895 7c4bf55eabdfc0b490ef43bfc6b68f3c 260 PANTHER PTHR24220:SF564 5 208 2.3E-111 T 13-09-2016 THL1_RS16565 148caf78bf29a0f65419612c66340de7 113 PANTHER PTHR30086 21 113 2.0E-17 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS16565 148caf78bf29a0f65419612c66340de7 113 PANTHER PTHR30086:SF3 21 113 2.0E-17 T 13-09-2016 THL1_RS16565 148caf78bf29a0f65419612c66340de7 113 Pfam PF01810 LysE type translocator 11 109 1.0E-7 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 Gene3D G3DSA:3.20.70.20 760 805 4.8E-82 T 13-09-2016 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 Gene3D G3DSA:3.20.70.20 547 704 4.8E-82 T 13-09-2016 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 Gene3D G3DSA:3.20.70.20 866 907 4.8E-82 T 13-09-2016 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 Gene3D G3DSA:3.20.70.20 282 492 4.8E-82 T 13-09-2016 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 297 907 1.8E-214 T 13-09-2016 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 SUPERFAMILY SSF48168 154 369 6.67E-63 T 13-09-2016 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 Pfam PF02867 Ribonucleotide reductase, barrel domain 371 905 6.7E-182 T 13-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 PRINTS PR01183 Ribonucleotide reductase large chain signature 656 678 8.4E-47 T 13-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 PRINTS PR01183 Ribonucleotide reductase large chain signature 684 707 8.4E-47 T 13-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 PRINTS PR01183 Ribonucleotide reductase large chain signature 581 592 8.4E-47 T 13-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 PRINTS PR01183 Ribonucleotide reductase large chain signature 446 465 8.4E-47 T 13-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 PRINTS PR01183 Ribonucleotide reductase large chain signature 618 641 8.4E-47 T 13-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 PRINTS PR01183 Ribonucleotide reductase large chain signature 760 787 8.4E-47 T 13-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 294 365 1.3E-21 T 13-09-2016 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 750 771 - T 13-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 Pfam PF03477 ATP cone domain 33 129 1.7E-17 T 13-09-2016 IPR005144 ATP-cone domain THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 Pfam PF03477 ATP cone domain 149 233 3.0E-8 T 13-09-2016 IPR005144 ATP-cone domain THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 PANTHER PTHR11573 150 965 0.0 T 13-09-2016 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 SUPERFAMILY SSF51998 840 907 6.71E-182 T 13-09-2016 THL1_RS08895 7d5232c22ef772331a930966ef8882d1 965 SUPERFAMILY SSF51998 370 809 6.71E-182 T 13-09-2016 THL1_RS26830 e4bcd8a2521bbb5a01819d4bf469ddb5 257 PANTHER PTHR24220 9 255 1.8E-159 T 13-09-2016 THL1_RS26830 e4bcd8a2521bbb5a01819d4bf469ddb5 257 Pfam PF00005 ABC transporter 23 182 1.2E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS26830 e4bcd8a2521bbb5a01819d4bf469ddb5 257 Gene3D G3DSA:3.40.50.300 6 254 1.3E-81 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26830 e4bcd8a2521bbb5a01819d4bf469ddb5 257 SMART SM00382 32 230 1.0E-15 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS26830 e4bcd8a2521bbb5a01819d4bf469ddb5 257 SUPERFAMILY SSF52540 8 252 3.63E-76 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26830 e4bcd8a2521bbb5a01819d4bf469ddb5 257 PANTHER PTHR24220:SF472 9 255 1.8E-159 T 13-09-2016 THL1_RS26830 e4bcd8a2521bbb5a01819d4bf469ddb5 257 PIRSF PIRSF039085 4 257 5.7E-117 T 13-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 THL1_RS26830 e4bcd8a2521bbb5a01819d4bf469ddb5 257 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS17510 b04d22b0a4abcec2bddc8bc3d8f46ce2 420 Pfam PF03573 outer membrane porin, OprD family 24 419 3.8E-141 T 13-09-2016 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 THL1_RS17510 b04d22b0a4abcec2bddc8bc3d8f46ce2 420 PANTHER PTHR34596 1 420 5.4E-151 T 13-09-2016 THL1_RS17510 b04d22b0a4abcec2bddc8bc3d8f46ce2 420 Gene3D G3DSA:2.40.160.10 29 420 3.9E-137 T 13-09-2016 IPR023614 Porin domain THL1_RS04020 e5173f13135d598e427f4e7cff899b7d 375 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 4 372 1.4E-160 T 13-09-2016 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 THL1_RS04020 e5173f13135d598e427f4e7cff899b7d 375 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 24 371 1.4E-124 T 13-09-2016 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain THL1_RS04020 e5173f13135d598e427f4e7cff899b7d 375 Gene3D G3DSA:3.40.50.2000 212 373 7.7E-66 T 13-09-2016 THL1_RS04020 e5173f13135d598e427f4e7cff899b7d 375 SUPERFAMILY SSF53756 1 374 8.57E-139 T 13-09-2016 THL1_RS04020 e5173f13135d598e427f4e7cff899b7d 375 PANTHER PTHR18964 1 373 6.0E-199 T 13-09-2016 THL1_RS04020 e5173f13135d598e427f4e7cff899b7d 375 PANTHER PTHR18964:SF2 1 373 6.0E-199 T 13-09-2016 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 THL1_RS04020 e5173f13135d598e427f4e7cff899b7d 375 Gene3D G3DSA:3.40.50.2000 2 211 1.1E-84 T 13-09-2016 THL1_RS16535 4c29a12bda3e8ebc40eef29ce37414d1 490 PIRSF PIRSF006060 4 485 7.8E-52 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS16535 4c29a12bda3e8ebc40eef29ce37414d1 490 Pfam PF13520 Amino acid permease 41 455 8.4E-26 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS16535 4c29a12bda3e8ebc40eef29ce37414d1 490 PANTHER PTHR11785 12 434 1.6E-29 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS16535 4c29a12bda3e8ebc40eef29ce37414d1 490 PANTHER PTHR11785 450 474 1.6E-29 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS26570 33cc571485af969a4567b240e5d9480d 193 ProSitePatterns PS00213 Lipocalin signature. 33 44 - T 13-09-2016 IPR022272 Lipocalin family conserved site THL1_RS26570 33cc571485af969a4567b240e5d9480d 193 Gene3D G3DSA:2.40.128.20 6 176 6.1E-53 T 13-09-2016 IPR012674 Calycin THL1_RS26570 33cc571485af969a4567b240e5d9480d 193 Pfam PF08212 Lipocalin-like domain 32 177 4.5E-58 T 13-09-2016 IPR000566 Lipocalin/cytosolic fatty-acid binding domain THL1_RS26570 33cc571485af969a4567b240e5d9480d 193 SUPERFAMILY SSF50814 10 181 5.3E-45 T 13-09-2016 IPR011038 Calycin-like THL1_RS26570 33cc571485af969a4567b240e5d9480d 193 PANTHER PTHR10612 4 192 3.1E-42 T 13-09-2016 THL1_RS26570 33cc571485af969a4567b240e5d9480d 193 PRINTS PR01171 Bacterial lipocalin signature 32 46 9.5E-12 T 13-09-2016 IPR002446 Lipocalin, bacterial GO:0005215 THL1_RS26570 33cc571485af969a4567b240e5d9480d 193 PRINTS PR01171 Bacterial lipocalin signature 168 178 9.5E-12 T 13-09-2016 IPR002446 Lipocalin, bacterial GO:0005215 THL1_RS26570 33cc571485af969a4567b240e5d9480d 193 PRINTS PR01171 Bacterial lipocalin signature 141 152 9.5E-12 T 13-09-2016 IPR002446 Lipocalin, bacterial GO:0005215 THL1_RS26570 33cc571485af969a4567b240e5d9480d 193 PRINTS PR01171 Bacterial lipocalin signature 49 65 9.5E-12 T 13-09-2016 IPR002446 Lipocalin, bacterial GO:0005215 THL1_RS26570 33cc571485af969a4567b240e5d9480d 193 PIRSF PIRSF036893 2 189 2.0E-57 T 13-09-2016 IPR022271 Lipocalin, ApoD type THL1_RS14575 400c13a9e5710f26f47db9dd15b0b9b0 364 Pfam PF13416 Bacterial extracellular solute-binding protein 42 320 2.1E-32 T 13-09-2016 THL1_RS14575 400c13a9e5710f26f47db9dd15b0b9b0 364 PIRSF PIRSF019574 2 362 1.3E-109 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS14575 400c13a9e5710f26f47db9dd15b0b9b0 364 Gene3D G3DSA:3.40.190.10 144 309 1.8E-57 T 13-09-2016 THL1_RS14575 400c13a9e5710f26f47db9dd15b0b9b0 364 PANTHER PTHR30222 6 360 7.6E-115 T 13-09-2016 THL1_RS14575 400c13a9e5710f26f47db9dd15b0b9b0 364 Gene3D G3DSA:3.40.190.10 39 143 2.9E-8 T 13-09-2016 THL1_RS14575 400c13a9e5710f26f47db9dd15b0b9b0 364 SUPERFAMILY SSF53850 24 359 2.93E-83 T 13-09-2016 THL1_RS14575 400c13a9e5710f26f47db9dd15b0b9b0 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 89 102 7.3E-48 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS14575 400c13a9e5710f26f47db9dd15b0b9b0 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 73 87 7.3E-48 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS14575 400c13a9e5710f26f47db9dd15b0b9b0 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 46 67 7.3E-48 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS14575 400c13a9e5710f26f47db9dd15b0b9b0 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 261 280 7.3E-48 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS14575 400c13a9e5710f26f47db9dd15b0b9b0 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 175 194 7.3E-48 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS14575 400c13a9e5710f26f47db9dd15b0b9b0 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 306 332 7.3E-48 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS14575 400c13a9e5710f26f47db9dd15b0b9b0 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 122 138 7.3E-48 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS14575 400c13a9e5710f26f47db9dd15b0b9b0 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 152 166 7.3E-48 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS14575 400c13a9e5710f26f47db9dd15b0b9b0 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 30 46 7.3E-48 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS14575 400c13a9e5710f26f47db9dd15b0b9b0 364 PANTHER PTHR30222:SF11 6 360 7.6E-115 T 13-09-2016 THL1_RS13650 2c3c09e644f376b90cd54e96e9924083 167 Pfam PF08592 Domain of unknown function (DUF1772) 24 157 7.9E-20 T 13-09-2016 IPR013901 Protein of unknown function DUF1772 THL1_RS23790 c8f3bc7f70d9ef04f90775bde583ed93 147 Pfam PF07366 SnoaL-like polyketide cyclase 10 134 1.3E-17 T 13-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain THL1_RS23790 c8f3bc7f70d9ef04f90775bde583ed93 147 SUPERFAMILY SSF54427 4 138 7.9E-25 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS23790 c8f3bc7f70d9ef04f90775bde583ed93 147 TIGRFAM TIGR02096 TIGR02096: conserved hypothetical protein 7 135 3.9E-35 T 13-09-2016 IPR011721 Conserved hypothetical protein CHP02096 THL1_RS23790 c8f3bc7f70d9ef04f90775bde583ed93 147 Gene3D G3DSA:3.10.450.50 5 138 2.7E-19 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS23790 c8f3bc7f70d9ef04f90775bde583ed93 147 PANTHER PTHR38436 2 145 5.4E-13 T 13-09-2016 THL1_RS05375 72156e341db6fe346777c8b77be4651b 178 Gene3D G3DSA:2.60.450.10 25 160 5.9E-33 T 13-09-2016 THL1_RS05375 72156e341db6fe346777c8b77be4651b 178 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 24 171 3.1E-48 T 13-09-2016 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 THL1_RS05375 72156e341db6fe346777c8b77be4651b 178 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 4 171 24.97 T 13-09-2016 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 THL1_RS05375 72156e341db6fe346777c8b77be4651b 178 PANTHER PTHR36504 1 177 2.0E-46 T 13-09-2016 THL1_RS05375 72156e341db6fe346777c8b77be4651b 178 Pfam PF03968 OstA-like protein 35 145 2.5E-27 T 13-09-2016 IPR005653 Organic solvent tolerance-like, N-terminal THL1_RS05235 009ab031f919bf9f36311de056e9c02a 405 PANTHER PTHR10804:SF86 153 392 3.0E-68 T 13-09-2016 THL1_RS05235 009ab031f919bf9f36311de056e9c02a 405 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 330 342 - T 13-09-2016 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site THL1_RS05235 009ab031f919bf9f36311de056e9c02a 405 PANTHER PTHR10804 153 392 3.0E-68 T 13-09-2016 THL1_RS05235 009ab031f919bf9f36311de056e9c02a 405 Pfam PF01321 Creatinase/Prolidase N-terminal domain 35 169 6.1E-15 T 13-09-2016 IPR000587 Creatinase, N-terminal GO:0016787 THL1_RS05235 009ab031f919bf9f36311de056e9c02a 405 SUPERFAMILY SSF53092 17 168 1.74E-21 T 13-09-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal THL1_RS05235 009ab031f919bf9f36311de056e9c02a 405 Gene3D G3DSA:3.90.230.10 171 397 3.2E-65 T 13-09-2016 IPR000994 Peptidase M24, structural domain THL1_RS05235 009ab031f919bf9f36311de056e9c02a 405 Pfam PF00557 Metallopeptidase family M24 178 383 3.9E-53 T 13-09-2016 IPR000994 Peptidase M24, structural domain THL1_RS05235 009ab031f919bf9f36311de056e9c02a 405 Gene3D G3DSA:3.40.350.10 17 167 2.9E-21 T 13-09-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal THL1_RS05235 009ab031f919bf9f36311de056e9c02a 405 SUPERFAMILY SSF55920 149 393 3.27E-69 T 13-09-2016 IPR000994 Peptidase M24, structural domain THL1_RS01455 3f248144e5bddf8255682dc4bd2ffb3d 504 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 13-09-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 THL1_RS01455 3f248144e5bddf8255682dc4bd2ffb3d 504 SUPERFAMILY SSF55021 410 503 1.33E-26 T 13-09-2016 THL1_RS01455 3f248144e5bddf8255682dc4bd2ffb3d 504 PANTHER PTHR10314 9 358 7.2E-205 T 13-09-2016 THL1_RS01455 3f248144e5bddf8255682dc4bd2ffb3d 504 SUPERFAMILY SSF55021 326 413 3.89E-28 T 13-09-2016 THL1_RS01455 3f248144e5bddf8255682dc4bd2ffb3d 504 PANTHER PTHR10314:SF30 9 358 7.2E-205 T 13-09-2016 THL1_RS01455 3f248144e5bddf8255682dc4bd2ffb3d 504 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 4 503 2.8E-245 T 13-09-2016 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19|UniPathway: UPA00047 THL1_RS01455 3f248144e5bddf8255682dc4bd2ffb3d 504 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 319 409 7.4E-25 T 13-09-2016 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19|UniPathway: UPA00047 THL1_RS01455 3f248144e5bddf8255682dc4bd2ffb3d 504 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 417 503 1.1E-21 T 13-09-2016 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19|UniPathway: UPA00047 THL1_RS01455 3f248144e5bddf8255682dc4bd2ffb3d 504 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 306 8.9E-82 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS01455 3f248144e5bddf8255682dc4bd2ffb3d 504 Gene3D G3DSA:3.40.1020.10 329 503 4.2E-56 T 13-09-2016 THL1_RS01455 3f248144e5bddf8255682dc4bd2ffb3d 504 Gene3D G3DSA:3.40.50.1100 69 325 1.3E-87 T 13-09-2016 THL1_RS01455 3f248144e5bddf8255682dc4bd2ffb3d 504 SUPERFAMILY SSF53686 11 355 5.89E-106 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS01220 22afddfa140897be42daa4b1c1cb071c 230 SUPERFAMILY SSF53955 52 222 3.09E-58 T 13-09-2016 IPR023346 Lysozyme-like domain THL1_RS01220 22afddfa140897be42daa4b1c1cb071c 230 PANTHER PTHR30400:SF0 1 229 3.9E-111 T 13-09-2016 THL1_RS01220 22afddfa140897be42daa4b1c1cb071c 230 Gene3D G3DSA:1.10.3810.10 53 222 7.9E-58 T 13-09-2016 THL1_RS01220 22afddfa140897be42daa4b1c1cb071c 230 Hamap MF_00766 Monofunctional biosynthetic peptidoglycan transglycosylase [mtgA]. 1 224 44.823 T 13-09-2016 IPR011812 Monofunctional biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 UniPathway: UPA00219 THL1_RS01220 22afddfa140897be42daa4b1c1cb071c 230 Pfam PF00912 Transglycosylase 54 218 2.0E-48 T 13-09-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 THL1_RS01220 22afddfa140897be42daa4b1c1cb071c 230 PANTHER PTHR30400 1 229 3.9E-111 T 13-09-2016 THL1_RS01220 22afddfa140897be42daa4b1c1cb071c 230 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 4 222 4.7E-96 T 13-09-2016 IPR011812 Monofunctional biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 UniPathway: UPA00219 THL1_RS23990 b29ae7f5bd3c62ffcc2289e0b1aa07ad 205 Hamap MF_00233 Outer-membrane lipoprotein LolB [lolB]. 1 200 26.427 T 13-09-2016 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 THL1_RS23990 b29ae7f5bd3c62ffcc2289e0b1aa07ad 205 SUPERFAMILY SSF89392 17 200 5.49E-51 T 13-09-2016 IPR029046 Lipoprotein localisation LolA/LolB/LppX THL1_RS23990 b29ae7f5bd3c62ffcc2289e0b1aa07ad 205 PANTHER PTHR30634:SF11 11 204 1.5E-48 T 13-09-2016 THL1_RS23990 b29ae7f5bd3c62ffcc2289e0b1aa07ad 205 Gene3D G3DSA:2.50.20.10 11 200 2.0E-62 T 13-09-2016 THL1_RS23990 b29ae7f5bd3c62ffcc2289e0b1aa07ad 205 PANTHER PTHR30634 11 204 1.5E-48 T 13-09-2016 THL1_RS23990 b29ae7f5bd3c62ffcc2289e0b1aa07ad 205 Pfam PF03550 Outer membrane lipoprotein LolB 48 198 1.0E-48 T 13-09-2016 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 THL1_RS23990 b29ae7f5bd3c62ffcc2289e0b1aa07ad 205 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 3 200 2.5E-77 T 13-09-2016 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 THL1_RS01585 0456f0a3f8ff7c4935ba24c9f26d06be 190 SMART SM00867 24 188 2.9E-60 T 13-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THL1_RS01585 0456f0a3f8ff7c4935ba24c9f26d06be 190 SUPERFAMILY SSF101874 21 189 1.14E-49 T 13-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THL1_RS01585 0456f0a3f8ff7c4935ba24c9f26d06be 190 Gene3D G3DSA:2.40.128.110 22 189 8.3E-54 T 13-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THL1_RS01585 0456f0a3f8ff7c4935ba24c9f26d06be 190 Pfam PF04264 YceI-like domain 32 186 2.7E-35 T 13-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THL1_RS01585 0456f0a3f8ff7c4935ba24c9f26d06be 190 PANTHER PTHR34406:SF1 1 189 6.3E-54 T 13-09-2016 THL1_RS01585 0456f0a3f8ff7c4935ba24c9f26d06be 190 PANTHER PTHR34406 1 189 6.3E-54 T 13-09-2016 THL1_RS27975 462c0a13a27d55d70e64e0dd2a890daa 184 SUPERFAMILY SSF64288 10 176 1.36E-50 T 13-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain THL1_RS27975 462c0a13a27d55d70e64e0dd2a890daa 184 PANTHER PTHR38683 1 184 1.6E-56 T 13-09-2016 THL1_RS27975 462c0a13a27d55d70e64e0dd2a890daa 184 Gene3D G3DSA:3.40.1410.10 10 176 9.8E-55 T 13-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain THL1_RS27975 462c0a13a27d55d70e64e0dd2a890daa 184 Pfam PF04345 Chorismate lyase 11 181 3.8E-56 T 13-09-2016 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|UniPathway: UPA00232 THL1_RS27975 462c0a13a27d55d70e64e0dd2a890daa 184 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 10 178 26.771 T 13-09-2016 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|UniPathway: UPA00232 THL1_RS27800 21ed39674caf020ea268a71933bb5025 121 SUPERFAMILY SSF51182 15 115 1.34E-22 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS27800 21ed39674caf020ea268a71933bb5025 121 Gene3D G3DSA:2.60.120.10 17 118 1.2E-36 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS27800 21ed39674caf020ea268a71933bb5025 121 Pfam PF05899 Protein of unknown function (DUF861) 41 113 7.9E-23 T 13-09-2016 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 THL1_RS27800 21ed39674caf020ea268a71933bb5025 121 PANTHER PTHR40943 1 121 1.8E-57 T 13-09-2016 THL1_RS16245 bd4e69f4d4cf267d7f07dcad063f6ca9 46 Pfam PF15723 Motility quorum-sensing regulator, toxin of MqsA 1 45 2.3E-17 T 13-09-2016 IPR031451 mRNA interferase MqsR GO:0009372|GO:0017148|GO:0042710 THL1_RS08790 a4c2ac4af87dbf06f82ed89837e6b183 308 Pfam PF00582 Universal stress protein family 133 272 3.2E-13 T 13-09-2016 IPR006016 UspA GO:0006950 THL1_RS08790 a4c2ac4af87dbf06f82ed89837e6b183 308 PANTHER PTHR31964 117 290 1.2E-43 T 13-09-2016 THL1_RS08790 a4c2ac4af87dbf06f82ed89837e6b183 308 SUPERFAMILY SSF52402 1 124 1.67E-13 T 13-09-2016 THL1_RS08790 a4c2ac4af87dbf06f82ed89837e6b183 308 PANTHER PTHR31964:SF41 117 290 1.2E-43 T 13-09-2016 THL1_RS08790 a4c2ac4af87dbf06f82ed89837e6b183 308 Gene3D G3DSA:3.40.50.620 2 120 1.4E-7 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS08790 a4c2ac4af87dbf06f82ed89837e6b183 308 SUPERFAMILY SSF52402 133 278 2.18E-15 T 13-09-2016 THL1_RS08790 a4c2ac4af87dbf06f82ed89837e6b183 308 Gene3D G3DSA:3.40.50.620 121 274 4.0E-18 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS11040 561007a1ba59d7237e5522441e00af0d 267 Pfam PF16234 Domain of unknown function (DUF4892) 19 200 1.7E-99 T 13-09-2016 IPR032608 Protein of unknown function DUF4892 THL1_RS06335 9157b3a705010fb1e2bb7d4d7b558245 156 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 2 149 1.0E-69 T 13-09-2016 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 UniPathway: UPA00344 THL1_RS06335 9157b3a705010fb1e2bb7d4d7b558245 156 PANTHER PTHR22960 2 155 3.9E-101 T 13-09-2016 THL1_RS06335 9157b3a705010fb1e2bb7d4d7b558245 156 Pfam PF01967 MoaC family 13 147 1.4E-56 T 13-09-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 UniPathway: UPA00344 THL1_RS06335 9157b3a705010fb1e2bb7d4d7b558245 156 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 1 155 35.832 T 13-09-2016 IPR023046 Molybdenum cofactor biosynthesis C, bacterial-type UniPathway: UPA00344 THL1_RS06335 9157b3a705010fb1e2bb7d4d7b558245 156 SUPERFAMILY SSF55040 9 152 6.15E-62 T 13-09-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 UniPathway: UPA00344 THL1_RS06335 9157b3a705010fb1e2bb7d4d7b558245 156 Gene3D G3DSA:3.30.70.640 2 154 2.1E-69 T 13-09-2016 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 UniPathway: UPA00344 THL1_RS04340 db2fad335a8efdda74e505f12b239fff 429 Gene3D G3DSA:3.40.640.10 70 316 6.4E-86 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS04340 db2fad335a8efdda74e505f12b239fff 429 Gene3D G3DSA:3.90.1150.10 2 69 6.1E-37 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS04340 db2fad335a8efdda74e505f12b239fff 429 Gene3D G3DSA:3.90.1150.10 319 424 6.1E-37 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS04340 db2fad335a8efdda74e505f12b239fff 429 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 426 105.283 T 13-09-2016 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188|UniPathway: UPA00251 THL1_RS04340 db2fad335a8efdda74e505f12b239fff 429 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 4 424 1.5E-187 T 13-09-2016 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188|UniPathway: UPA00251 THL1_RS04340 db2fad335a8efdda74e505f12b239fff 429 SUPERFAMILY SSF53383 2 423 2.13E-134 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS04340 db2fad335a8efdda74e505f12b239fff 429 Pfam PF00202 Aminotransferase class-III 33 395 1.5E-75 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS04340 db2fad335a8efdda74e505f12b239fff 429 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS04340 db2fad335a8efdda74e505f12b239fff 429 PANTHER PTHR11986 1 429 5.5E-228 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS04340 db2fad335a8efdda74e505f12b239fff 429 PANTHER PTHR11986:SF5 1 429 5.5E-228 T 13-09-2016 THL1_RS09340 174fc9559a3fc50f93e4877fddc8f0f2 451 Gene3D G3DSA:1.20.1600.10 16 425 7.2E-57 T 13-09-2016 THL1_RS09340 174fc9559a3fc50f93e4877fddc8f0f2 451 Pfam PF02321 Outer membrane efflux protein 245 414 8.9E-21 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS09340 174fc9559a3fc50f93e4877fddc8f0f2 451 Pfam PF02321 Outer membrane efflux protein 26 217 8.0E-23 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS09340 174fc9559a3fc50f93e4877fddc8f0f2 451 PANTHER PTHR30026:SF4 1 447 4.4E-71 T 13-09-2016 THL1_RS09340 174fc9559a3fc50f93e4877fddc8f0f2 451 PANTHER PTHR30026 1 447 4.4E-71 T 13-09-2016 THL1_RS09340 174fc9559a3fc50f93e4877fddc8f0f2 451 SUPERFAMILY SSF56954 23 430 9.94E-76 T 13-09-2016 THL1_RS09340 174fc9559a3fc50f93e4877fddc8f0f2 451 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 21 428 9.4E-91 T 13-09-2016 IPR010130 Type I secretion outer membrane protein, TolC GO:0006810|GO:0019867 THL1_RS00145 4759c395e44cfcd365b2ab09745ac78e 308 Gene3D G3DSA:3.40.190.10 233 296 3.2E-41 T 13-09-2016 THL1_RS00145 4759c395e44cfcd365b2ab09745ac78e 308 Gene3D G3DSA:3.40.190.10 24 111 3.2E-41 T 13-09-2016 THL1_RS00145 4759c395e44cfcd365b2ab09745ac78e 308 PANTHER PTHR30177 1 284 1.3E-94 T 13-09-2016 THL1_RS00145 4759c395e44cfcd365b2ab09745ac78e 308 PANTHER PTHR30177:SF6 1 284 1.3E-94 T 13-09-2016 THL1_RS00145 4759c395e44cfcd365b2ab09745ac78e 308 TIGRFAM TIGR03414 ABC_choline_bnd: choline ABC transporter, periplasmic binding protein 22 308 3.5E-130 T 13-09-2016 IPR017783 ABC transporter, choline, substrate-binding protein GO:0015871|GO:0033265|GO:0042597 THL1_RS00145 4759c395e44cfcd365b2ab09745ac78e 308 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 30 280 1.8E-59 T 13-09-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 THL1_RS00145 4759c395e44cfcd365b2ab09745ac78e 308 Gene3D G3DSA:3.40.190.100 116 232 5.5E-25 T 13-09-2016 THL1_RS00145 4759c395e44cfcd365b2ab09745ac78e 308 SUPERFAMILY SSF53850 26 296 6.24E-82 T 13-09-2016 THL1_RS22790 350979dcae2847c511de8199517c8d36 211 Gene3D G3DSA:1.10.10.60 13 63 6.0E-22 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS22790 350979dcae2847c511de8199517c8d36 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 6.0E-11 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS22790 350979dcae2847c511de8199517c8d36 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 6.0E-11 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS22790 350979dcae2847c511de8199517c8d36 211 PANTHER PTHR30055 5 211 3.1E-42 T 13-09-2016 THL1_RS22790 350979dcae2847c511de8199517c8d36 211 PANTHER PTHR30055:SF76 5 211 3.1E-42 T 13-09-2016 THL1_RS22790 350979dcae2847c511de8199517c8d36 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 2.1E-16 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS22790 350979dcae2847c511de8199517c8d36 211 Gene3D G3DSA:1.10.357.10 64 211 4.8E-40 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS22790 350979dcae2847c511de8199517c8d36 211 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 155 209 8.3E-13 T 13-09-2016 THL1_RS22790 350979dcae2847c511de8199517c8d36 211 SUPERFAMILY SSF46689 12 90 1.4E-18 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS22790 350979dcae2847c511de8199517c8d36 211 SUPERFAMILY SSF48498 88 208 9.78E-6 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS18710 96bc684ed110a0b59b252ffb965eae78 375 PANTHER PTHR40697 1 375 6.9E-233 T 13-09-2016 THL1_RS18710 96bc684ed110a0b59b252ffb965eae78 375 SUPERFAMILY SSF111331 89 140 2.83E-5 T 13-09-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain THL1_RS18710 96bc684ed110a0b59b252ffb965eae78 375 Gene3D G3DSA:3.40.50.10330 89 143 8.3E-4 T 13-09-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 THL1_RS18710 96bc684ed110a0b59b252ffb965eae78 375 PANTHER PTHR40697:SF1 1 375 6.9E-233 T 13-09-2016 THL1_RS18710 96bc684ed110a0b59b252ffb965eae78 375 Pfam PF01513 ATP-NAD kinase 7 367 2.5E-59 T 13-09-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 THL1_RS18710 96bc684ed110a0b59b252ffb965eae78 375 PIRSF PIRSF016907 2 370 7.8E-137 T 13-09-2016 IPR011386 Putative ATP-NAD kinase THL1_RS11575 451d07adcb842e53846a571281e76bc2 290 Gene3D G3DSA:3.30.2010.10 72 159 3.5E-30 T 13-09-2016 THL1_RS11575 451d07adcb842e53846a571281e76bc2 290 PANTHER PTHR10120:SF19 1 288 7.7E-95 T 13-09-2016 THL1_RS11575 451d07adcb842e53846a571281e76bc2 290 PANTHER PTHR10120 1 288 7.7E-95 T 13-09-2016 THL1_RS11575 451d07adcb842e53846a571281e76bc2 290 Hamap MF_00188 Protease HtpX [htpX]. 1 289 24.872 T 13-09-2016 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 THL1_RS11575 451d07adcb842e53846a571281e76bc2 290 Pfam PF01435 Peptidase family M48 77 289 1.3E-36 T 13-09-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 THL1_RS08500 3812583c5775b033fe4f7f46256c5f00 351 Pfam PF00005 ABC transporter 20 161 1.8E-37 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS08500 3812583c5775b033fe4f7f46256c5f00 351 PANTHER PTHR24220 5 243 3.8E-124 T 13-09-2016 THL1_RS08500 3812583c5775b033fe4f7f46256c5f00 351 SMART SM00382 28 211 2.9E-19 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS08500 3812583c5775b033fe4f7f46256c5f00 351 Pfam PF08402 TOBE domain 274 349 1.1E-9 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS08500 3812583c5775b033fe4f7f46256c5f00 351 PANTHER PTHR24220:SF150 5 243 3.8E-124 T 13-09-2016 THL1_RS08500 3812583c5775b033fe4f7f46256c5f00 351 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS08500 3812583c5775b033fe4f7f46256c5f00 351 SUPERFAMILY SSF52540 5 241 8.52E-85 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08500 3812583c5775b033fe4f7f46256c5f00 351 Gene3D G3DSA:3.40.50.300 5 234 7.5E-80 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08500 3812583c5775b033fe4f7f46256c5f00 351 SUPERFAMILY SSF50331 238 349 1.67E-14 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 Gene3D G3DSA:3.30.230.10 585 766 2.3E-75 T 13-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 Hamap MF_01973 Lon protease [lon]. 7 767 71.274 T 13-09-2016 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 SUPERFAMILY SSF52540 308 581 3.05E-54 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 SMART SM00464 6 198 6.2E-76 T 13-09-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 698 717 8.1E-54 T 13-09-2016 THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 590 606 8.1E-54 T 13-09-2016 THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 721 739 8.1E-54 T 13-09-2016 THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 668 687 8.1E-54 T 13-09-2016 THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 352 371 8.1E-54 T 13-09-2016 THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 TIGRFAM TIGR00763 lon: endopeptidase La 8 766 2.1E-301 T 13-09-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 6 197 2.1E-42 T 13-09-2016 IPR003111 ATP-dependent protease La (LON), substrate-binding domain GO:0004176|GO:0006508 THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 Gene3D G3DSA:1.10.8.60 497 579 2.3E-32 T 13-09-2016 THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 PANTHER PTHR10046:SF43 1 771 0.0 T 13-09-2016 THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 Gene3D G3DSA:3.40.50.300 304 496 7.8E-34 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 SMART SM00382 344 488 2.2E-12 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 PIRSF PIRSF001174 1 770 0.0 T 13-09-2016 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 SUPERFAMILY SSF54211 590 765 4.17E-58 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 565 767 4.3E-98 T 13-09-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 SUPERFAMILY SSF88697 6 197 4.22E-50 T 13-09-2016 IPR015947 PUA-like domain THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 348 484 1.3E-18 T 13-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 THL1_RS17985 09d26f7eb2e2f7b524b2cb8ec293d964 798 PANTHER PTHR10046 1 771 0.0 T 13-09-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 THL1_RS20760 61dd9f6650fb264654a50fac7df6156e 478 Pfam PF01609 Transposase DDE domain 232 460 5.8E-16 T 13-09-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THL1_RS20760 61dd9f6650fb264654a50fac7df6156e 478 Pfam PF05598 Transposase domain (DUF772) 56 120 1.8E-18 T 13-09-2016 IPR008490 Transposase InsH, N-terminal THL1_RS20760 61dd9f6650fb264654a50fac7df6156e 478 PANTHER PTHR33408 1 475 1.2E-180 T 13-09-2016 THL1_RS20760 61dd9f6650fb264654a50fac7df6156e 478 PANTHER PTHR33408:SF2 1 475 1.2E-180 T 13-09-2016 THL1_RS11420 7fe5cc3035796da130eee4753a1fa132 502 PANTHER PTHR11699:SF181 1 499 0.0 T 13-09-2016 THL1_RS11420 7fe5cc3035796da130eee4753a1fa132 502 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 9 485 1.1E-226 T 13-09-2016 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373 THL1_RS11420 7fe5cc3035796da130eee4753a1fa132 502 Gene3D G3DSA:3.40.605.10 8 265 7.0E-101 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS11420 7fe5cc3035796da130eee4753a1fa132 502 SUPERFAMILY SSF53720 4 488 1.96E-149 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS11420 7fe5cc3035796da130eee4753a1fa132 502 Gene3D G3DSA:3.40.309.10 266 446 5.3E-67 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS11420 7fe5cc3035796da130eee4753a1fa132 502 Pfam PF00171 Aldehyde dehydrogenase family 17 481 3.2E-142 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS11420 7fe5cc3035796da130eee4753a1fa132 502 PANTHER PTHR11699 1 499 0.0 T 13-09-2016 THL1_RS11350 fd167688c219353aa859c5d78caccb5b 401 Gene3D G3DSA:3.40.47.10 185 284 7.9E-58 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS11350 fd167688c219353aa859c5d78caccb5b 401 Gene3D G3DSA:3.40.47.10 4 126 7.9E-58 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS11350 fd167688c219353aa859c5d78caccb5b 401 PANTHER PTHR18919 1 228 2.4E-247 T 13-09-2016 THL1_RS11350 fd167688c219353aa859c5d78caccb5b 401 PANTHER PTHR18919 249 401 2.4E-247 T 13-09-2016 THL1_RS11350 fd167688c219353aa859c5d78caccb5b 401 Pfam PF02803 Thiolase, C-terminal domain 278 400 3.3E-47 T 13-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THL1_RS11350 fd167688c219353aa859c5d78caccb5b 401 Pfam PF00108 Thiolase, N-terminal domain 5 229 2.4E-46 T 13-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THL1_RS11350 fd167688c219353aa859c5d78caccb5b 401 PIRSF PIRSF000429 1 401 9.1E-112 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS11350 fd167688c219353aa859c5d78caccb5b 401 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 399 1.2E-130 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS11350 fd167688c219353aa859c5d78caccb5b 401 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 13-09-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 THL1_RS11350 fd167688c219353aa859c5d78caccb5b 401 PANTHER PTHR18919:SF12 1 228 2.4E-247 T 13-09-2016 THL1_RS11350 fd167688c219353aa859c5d78caccb5b 401 PANTHER PTHR18919:SF12 249 401 2.4E-247 T 13-09-2016 THL1_RS11350 fd167688c219353aa859c5d78caccb5b 401 SUPERFAMILY SSF53901 1 275 8.73E-63 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS11350 fd167688c219353aa859c5d78caccb5b 401 SUPERFAMILY SSF53901 279 399 7.6E-44 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS11350 fd167688c219353aa859c5d78caccb5b 401 Gene3D G3DSA:3.40.47.10 145 184 1.2E-58 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS11350 fd167688c219353aa859c5d78caccb5b 401 Gene3D G3DSA:3.40.47.10 285 400 1.2E-58 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS11350 fd167688c219353aa859c5d78caccb5b 401 ProSitePatterns PS00099 Thiolases active site. 382 395 - T 13-09-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 THL1_RS11350 fd167688c219353aa859c5d78caccb5b 401 ProSitePatterns PS00737 Thiolases signature 2. 347 363 - T 13-09-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 THL1_RS19360 ced8d966ae81304ebecc9086cee14de9 332 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 16 328 1.2E-132 T 13-09-2016 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 THL1_RS19360 ced8d966ae81304ebecc9086cee14de9 332 Gene3D G3DSA:3.40.190.10 192 297 1.2E-23 T 13-09-2016 THL1_RS19360 ced8d966ae81304ebecc9086cee14de9 332 Gene3D G3DSA:3.40.190.10 25 169 2.9E-48 T 13-09-2016 THL1_RS19360 ced8d966ae81304ebecc9086cee14de9 332 Pfam PF13531 Bacterial extracellular solute-binding protein 30 280 1.5E-40 T 13-09-2016 THL1_RS19360 ced8d966ae81304ebecc9086cee14de9 332 PANTHER PTHR30368:SF2 7 332 4.0E-168 T 13-09-2016 THL1_RS19360 ced8d966ae81304ebecc9086cee14de9 332 SUPERFAMILY SSF53850 22 329 1.17E-83 T 13-09-2016 THL1_RS19360 ced8d966ae81304ebecc9086cee14de9 332 PANTHER PTHR30368 7 332 4.0E-168 T 13-09-2016 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 THL1_RS05530 7cfa9a8ddbfa80444ad40df87ac9b27e 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 141 3.6E-66 T 13-09-2016 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 THL1_RS05530 7cfa9a8ddbfa80444ad40df87ac9b27e 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 13-09-2016 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 THL1_RS05530 7cfa9a8ddbfa80444ad40df87ac9b27e 142 PANTHER PTHR11545 1 142 1.9E-77 T 13-09-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 THL1_RS05530 7cfa9a8ddbfa80444ad40df87ac9b27e 142 Pfam PF00572 Ribosomal protein L13 15 138 9.7E-59 T 13-09-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 THL1_RS05530 7cfa9a8ddbfa80444ad40df87ac9b27e 142 Gene3D G3DSA:3.90.1180.10 3 141 6.4E-66 T 13-09-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 THL1_RS05530 7cfa9a8ddbfa80444ad40df87ac9b27e 142 SUPERFAMILY SSF52161 1 139 9.42E-61 T 13-09-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 THL1_RS05530 7cfa9a8ddbfa80444ad40df87ac9b27e 142 PIRSF PIRSF002181 1 142 5.5E-53 T 13-09-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 THL1_RS05530 7cfa9a8ddbfa80444ad40df87ac9b27e 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 29.724 T 13-09-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 THL1_RS04820 e2625df20db21089f90676da2ace3b43 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 13-09-2016 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS04820 e2625df20db21089f90676da2ace3b43 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 1.0E-40 T 13-09-2016 IPR028909 Ribosomal protein L21-like GO:0005840 THL1_RS04820 e2625df20db21089f90676da2ace3b43 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.665 T 13-09-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS04820 e2625df20db21089f90676da2ace3b43 103 PANTHER PTHR21349 1 102 1.0E-45 T 13-09-2016 THL1_RS04820 e2625df20db21089f90676da2ace3b43 103 SUPERFAMILY SSF141091 1 102 1.96E-39 T 13-09-2016 IPR028909 Ribosomal protein L21-like GO:0005840 THL1_RS04820 e2625df20db21089f90676da2ace3b43 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 102 3.3E-43 T 13-09-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS20560 55339ed0b2e2bded69265f07d28535ad 200 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 8 194 1.9E-78 T 13-09-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 THL1_RS20560 55339ed0b2e2bded69265f07d28535ad 200 SUPERFAMILY SSF142695 4 172 2.22E-66 T 13-09-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 THL1_RS20560 55339ed0b2e2bded69265f07d28535ad 200 Pfam PF00925 GTP cyclohydrolase II 7 169 3.0E-69 T 13-09-2016 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 THL1_RS20560 55339ed0b2e2bded69265f07d28535ad 200 PANTHER PTHR21327 1 197 2.5E-110 T 13-09-2016 THL1_RS20560 55339ed0b2e2bded69265f07d28535ad 200 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 1 196 44.151 T 13-09-2016 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|UniPathway: UPA00275 THL1_RS20560 55339ed0b2e2bded69265f07d28535ad 200 PANTHER PTHR21327:SF14 1 197 2.5E-110 T 13-09-2016 THL1_RS03895 a76922e0f48922f40c77f741a28a31bc 265 PANTHER PTHR30535 21 261 2.4E-47 T 13-09-2016 THL1_RS03895 a76922e0f48922f40c77f741a28a31bc 265 Gene3D G3DSA:3.40.50.1980 21 137 1.1E-26 T 13-09-2016 THL1_RS03895 a76922e0f48922f40c77f741a28a31bc 265 Gene3D G3DSA:3.40.50.1980 141 262 2.1E-31 T 13-09-2016 THL1_RS03895 a76922e0f48922f40c77f741a28a31bc 265 Pfam PF01497 Periplasmic binding protein 22 236 8.3E-23 T 13-09-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 THL1_RS03895 a76922e0f48922f40c77f741a28a31bc 265 SUPERFAMILY SSF53807 21 261 1.65E-53 T 13-09-2016 THL1_RS19895 3ed7d647041fbb5f26bd85973eb26eaf 219 PANTHER PTHR12192:SF9 30 208 2.7E-42 T 13-09-2016 THL1_RS19895 3ed7d647041fbb5f26bd85973eb26eaf 219 Pfam PF04752 ChaC-like protein 44 205 4.9E-38 T 13-09-2016 IPR006840 ChaC-like protein THL1_RS19895 3ed7d647041fbb5f26bd85973eb26eaf 219 PANTHER PTHR12192 30 208 2.7E-42 T 13-09-2016 IPR006840 ChaC-like protein THL1_RS19895 3ed7d647041fbb5f26bd85973eb26eaf 219 SUPERFAMILY SSF110857 44 155 6.02E-10 T 13-09-2016 IPR013024 Butirosin biosynthesis, BtrG-like THL1_RS19895 3ed7d647041fbb5f26bd85973eb26eaf 219 Gene3D G3DSA:3.10.490.10 39 205 5.1E-26 T 13-09-2016 IPR013024 Butirosin biosynthesis, BtrG-like THL1_RS02455 4d175b09b1ab4686ee9d35b710b1cdc5 256 Gene3D G3DSA:3.90.850.10 2 254 2.1E-66 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS02455 4d175b09b1ab4686ee9d35b710b1cdc5 256 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 101 254 3.5E-12 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS02455 4d175b09b1ab4686ee9d35b710b1cdc5 256 PANTHER PTHR30143 4 249 2.8E-49 T 13-09-2016 THL1_RS02455 4d175b09b1ab4686ee9d35b710b1cdc5 256 SUPERFAMILY SSF56529 4 254 1.47E-61 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS22490 e29f540d37a983f17397d31c6942c25c 282 PANTHER PTHR21666 163 282 2.5E-42 T 13-09-2016 THL1_RS22490 e29f540d37a983f17397d31c6942c25c 282 Gene3D G3DSA:2.70.70.10 142 280 9.4E-40 T 13-09-2016 THL1_RS22490 e29f540d37a983f17397d31c6942c25c 282 Pfam PF01476 LysM domain 52 93 1.8E-11 T 13-09-2016 IPR018392 LysM domain THL1_RS22490 e29f540d37a983f17397d31c6942c25c 282 Pfam PF01551 Peptidase family M23 182 275 7.1E-31 T 13-09-2016 IPR016047 Peptidase M23 THL1_RS22490 e29f540d37a983f17397d31c6942c25c 282 SMART SM00257 51 95 2.6E-9 T 13-09-2016 IPR018392 LysM domain THL1_RS22490 e29f540d37a983f17397d31c6942c25c 282 SUPERFAMILY SSF51261 52 279 5.75E-52 T 13-09-2016 IPR011055 Duplicated hybrid motif THL1_RS22490 e29f540d37a983f17397d31c6942c25c 282 Gene3D G3DSA:3.10.350.10 51 93 6.9E-13 T 13-09-2016 IPR018392 LysM domain THL1_RS09180 a8f02020ff3d85e5cc6986ee0be42b3e 174 Pfam PF11157 Protein of unknown function (DUF2937) 2 158 6.3E-59 T 13-09-2016 IPR022584 Protein of unknown function DUF2937 THL1_RS09180 a8f02020ff3d85e5cc6986ee0be42b3e 174 PIRSF PIRSF029393 1 172 4.8E-69 T 13-09-2016 IPR016917 Uncharacterised conserved protein UCP029393 THL1_RS15685 fa95e2c81d409f08b34da20f4addb8a8 199 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 3.2E-6 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS15685 fa95e2c81d409f08b34da20f4addb8a8 199 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 41 2.2E-5 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS15685 fa95e2c81d409f08b34da20f4addb8a8 199 Gene3D G3DSA:2.160.10.10 4 167 1.6E-37 T 13-09-2016 THL1_RS15685 fa95e2c81d409f08b34da20f4addb8a8 199 TIGRFAM TIGR02287 PaaY: phenylacetic acid degradation protein PaaY 3 194 6.5E-105 T 13-09-2016 IPR011974 Phenylacetic acid degradation protein PaaY UniPathway: UPA00930 THL1_RS15685 fa95e2c81d409f08b34da20f4addb8a8 199 SUPERFAMILY SSF51161 3 168 1.33E-41 T 13-09-2016 IPR011004 Trimeric LpxA-like THL1_RS15685 fa95e2c81d409f08b34da20f4addb8a8 199 PANTHER PTHR13061 1 185 9.5E-54 T 13-09-2016 THL1_RS28105 680748239eafea1dfb91393d07c993a5 507 Gene3D G3DSA:2.60.40.420 357 486 9.5E-26 T 13-09-2016 IPR008972 Cupredoxin THL1_RS28105 680748239eafea1dfb91393d07c993a5 507 PANTHER PTHR11709 12 112 6.1E-60 T 13-09-2016 THL1_RS28105 680748239eafea1dfb91393d07c993a5 507 PANTHER PTHR11709:SF2 12 112 6.1E-60 T 13-09-2016 THL1_RS28105 680748239eafea1dfb91393d07c993a5 507 Pfam PF07731 Multicopper oxidase 369 485 3.2E-19 T 13-09-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 THL1_RS28105 680748239eafea1dfb91393d07c993a5 507 ProSitePatterns PS00080 Multicopper oxidases signature 2. 468 479 - T 13-09-2016 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 THL1_RS28105 680748239eafea1dfb91393d07c993a5 507 SUPERFAMILY SSF49503 365 484 2.52E-21 T 13-09-2016 IPR008972 Cupredoxin THL1_RS28105 680748239eafea1dfb91393d07c993a5 507 PANTHER PTHR11709 128 488 6.1E-60 T 13-09-2016 THL1_RS28105 680748239eafea1dfb91393d07c993a5 507 Gene3D G3DSA:2.60.40.420 173 294 3.6E-22 T 13-09-2016 IPR008972 Cupredoxin THL1_RS28105 680748239eafea1dfb91393d07c993a5 507 SUPERFAMILY SSF49503 177 298 3.48E-16 T 13-09-2016 IPR008972 Cupredoxin THL1_RS28105 680748239eafea1dfb91393d07c993a5 507 PANTHER PTHR11709:SF2 128 488 6.1E-60 T 13-09-2016 THL1_RS28105 680748239eafea1dfb91393d07c993a5 507 Gene3D G3DSA:2.60.40.420 16 160 2.3E-11 T 13-09-2016 IPR008972 Cupredoxin THL1_RS28105 680748239eafea1dfb91393d07c993a5 507 SUPERFAMILY SSF49503 17 85 1.83E-12 T 13-09-2016 IPR008972 Cupredoxin THL1_RS28105 680748239eafea1dfb91393d07c993a5 507 SUPERFAMILY SSF49503 132 160 1.83E-12 T 13-09-2016 IPR008972 Cupredoxin THL1_RS21790 c68af91f1ae3f24c3500546560acb973 252 PANTHER PTHR24321:SF6 2 248 3.5E-51 T 13-09-2016 THL1_RS21790 c68af91f1ae3f24c3500546560acb973 252 PANTHER PTHR24321 2 248 3.5E-51 T 13-09-2016 THL1_RS21790 c68af91f1ae3f24c3500546560acb973 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 4.7E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21790 c68af91f1ae3f24c3500546560acb973 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 4.7E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21790 c68af91f1ae3f24c3500546560acb973 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 4.7E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21790 c68af91f1ae3f24c3500546560acb973 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 4.7E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21790 c68af91f1ae3f24c3500546560acb973 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.7E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21790 c68af91f1ae3f24c3500546560acb973 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.7E-38 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21790 c68af91f1ae3f24c3500546560acb973 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 4.0E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21790 c68af91f1ae3f24c3500546560acb973 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 4.0E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21790 c68af91f1ae3f24c3500546560acb973 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 4.0E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21790 c68af91f1ae3f24c3500546560acb973 252 SUPERFAMILY SSF51735 5 248 1.58E-78 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS21790 c68af91f1ae3f24c3500546560acb973 252 Gene3D G3DSA:3.40.50.720 2 246 3.9E-82 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS21790 c68af91f1ae3f24c3500546560acb973 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 183 0.0064 T 13-09-2016 THL1_RS21790 c68af91f1ae3f24c3500546560acb973 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS21790 c68af91f1ae3f24c3500546560acb973 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 243 1.9E-63 T 13-09-2016 THL1_RS07030 6bb845cf72b0a28ef1551452be2bd0b4 405 SUPERFAMILY SSF51569 14 282 2.75E-35 T 13-09-2016 THL1_RS07030 6bb845cf72b0a28ef1551452be2bd0b4 405 Gene3D G3DSA:3.20.20.70 14 280 1.0E-31 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS07030 6bb845cf72b0a28ef1551452be2bd0b4 405 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 205 218 - T 13-09-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 THL1_RS07030 6bb845cf72b0a28ef1551452be2bd0b4 405 PANTHER PTHR10277:SF47 164 294 1.5E-18 T 13-09-2016 THL1_RS07030 6bb845cf72b0a28ef1551452be2bd0b4 405 PANTHER PTHR10277 164 294 1.5E-18 T 13-09-2016 THL1_RS07030 6bb845cf72b0a28ef1551452be2bd0b4 405 Pfam PF00682 HMGL-like 14 270 2.0E-28 T 13-09-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 THL1_RS25290 908c1c3c946f26c4a081f795a8f9d716 196 SMART SM00926 44 105 1.9E-22 T 13-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 THL1_RS25290 908c1c3c946f26c4a081f795a8f9d716 196 Gene3D G3DSA:2.20.25.90 39 109 5.8E-25 T 13-09-2016 THL1_RS25290 908c1c3c946f26c4a081f795a8f9d716 196 Gene3D G3DSA:3.40.50.740 110 174 7.8E-15 T 13-09-2016 THL1_RS25290 908c1c3c946f26c4a081f795a8f9d716 196 SUPERFAMILY SSF53706 37 196 8.9E-55 T 13-09-2016 THL1_RS25290 908c1c3c946f26c4a081f795a8f9d716 196 PANTHER PTHR11615 46 196 1.4E-88 T 13-09-2016 THL1_RS25290 908c1c3c946f26c4a081f795a8f9d716 196 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 46 104 3.6E-19 T 13-09-2016 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 THL1_RS25290 908c1c3c946f26c4a081f795a8f9d716 196 PANTHER PTHR11615:SF126 46 196 1.4E-88 T 13-09-2016 THL1_RS25290 908c1c3c946f26c4a081f795a8f9d716 196 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 49 67 - T 13-09-2016 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 THL1_RS25290 908c1c3c946f26c4a081f795a8f9d716 196 Pfam PF00384 Molybdopterin oxidoreductase 108 143 1.9E-6 T 13-09-2016 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 THL1_RS05475 8790a51a56d0705747307f5a7b683d84 305 PANTHER PTHR23293 1 157 4.2E-96 T 13-09-2016 THL1_RS05475 8790a51a56d0705747307f5a7b683d84 305 PANTHER PTHR23293:SF6 1 157 4.2E-96 T 13-09-2016 THL1_RS05475 8790a51a56d0705747307f5a7b683d84 305 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 8 305 3.1E-159 T 13-09-2016 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 THL1_RS05475 8790a51a56d0705747307f5a7b683d84 305 PANTHER PTHR23293 177 210 4.2E-96 T 13-09-2016 THL1_RS05475 8790a51a56d0705747307f5a7b683d84 305 PANTHER PTHR23293:SF6 177 210 4.2E-96 T 13-09-2016 THL1_RS05475 8790a51a56d0705747307f5a7b683d84 305 PANTHER PTHR23293 248 305 4.2E-96 T 13-09-2016 THL1_RS05475 8790a51a56d0705747307f5a7b683d84 305 Gene3D G3DSA:3.40.50.620 247 256 8.2E-64 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS05475 8790a51a56d0705747307f5a7b683d84 305 Gene3D G3DSA:3.40.50.620 5 209 8.2E-64 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS05475 8790a51a56d0705747307f5a7b683d84 305 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 3 305 56.963 T 13-09-2016 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 THL1_RS05475 8790a51a56d0705747307f5a7b683d84 305 PIRSF PIRSF002936 1 305 2.1E-155 T 13-09-2016 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|UniPathway: UPA00140 THL1_RS05475 8790a51a56d0705747307f5a7b683d84 305 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 28 260 1.3E-66 T 13-09-2016 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 THL1_RS05475 8790a51a56d0705747307f5a7b683d84 305 PANTHER PTHR23293:SF6 248 305 4.2E-96 T 13-09-2016 THL1_RS05475 8790a51a56d0705747307f5a7b683d84 305 SUPERFAMILY SSF52402 5 209 2.12E-76 T 13-09-2016 THL1_RS24060 54f5024fa1b9bfc6ee76c63e83a11537 332 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 226 245 - T 13-09-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 THL1_RS24060 54f5024fa1b9bfc6ee76c63e83a11537 332 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 318 2.9E-82 T 13-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 THL1_RS24060 54f5024fa1b9bfc6ee76c63e83a11537 332 Gene3D G3DSA:3.40.718.10 2 318 1.4E-99 T 13-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 THL1_RS24060 54f5024fa1b9bfc6ee76c63e83a11537 332 SUPERFAMILY SSF53659 2 311 5.95E-96 T 13-09-2016 THL1_RS24060 54f5024fa1b9bfc6ee76c63e83a11537 332 SMART SM01329 3 328 1.4E-127 T 13-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 THL1_RS24060 54f5024fa1b9bfc6ee76c63e83a11537 332 PANTHER PTHR11835 2 310 7.5E-114 T 13-09-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 THL1_RS08995 9b75965af8c7e703fd5ab29bbf78516e 216 PANTHER PTHR10509 1 216 3.2E-89 T 13-09-2016 THL1_RS08995 9b75965af8c7e703fd5ab29bbf78516e 216 Gene3D G3DSA:3.40.50.150 3 216 4.4E-76 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS08995 9b75965af8c7e703fd5ab29bbf78516e 216 PANTHER PTHR10509:SF14 1 216 3.2E-89 T 13-09-2016 THL1_RS08995 9b75965af8c7e703fd5ab29bbf78516e 216 Pfam PF01596 O-methyltransferase 21 215 4.3E-66 T 13-09-2016 IPR002935 O-methyltransferase, family 3 GO:0008171 THL1_RS08995 9b75965af8c7e703fd5ab29bbf78516e 216 SUPERFAMILY SSF53335 9 216 6.19E-48 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS19420 48a85b3a5f9c10b565f2018e53ec30a0 148 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 2 141 33.898 T 13-09-2016 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 THL1_RS19420 48a85b3a5f9c10b565f2018e53ec30a0 148 Pfam PF03100 CcmE 5 131 1.1E-47 T 13-09-2016 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 THL1_RS19420 48a85b3a5f9c10b565f2018e53ec30a0 148 Gene3D G3DSA:2.40.50.140 27 125 1.3E-39 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS19420 48a85b3a5f9c10b565f2018e53ec30a0 148 PANTHER PTHR34128 2 147 1.8E-69 T 13-09-2016 THL1_RS19420 48a85b3a5f9c10b565f2018e53ec30a0 148 SUPERFAMILY SSF82093 30 137 1.44E-41 T 13-09-2016 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004 THL1_RS19420 48a85b3a5f9c10b565f2018e53ec30a0 148 PANTHER PTHR34128:SF1 2 147 1.8E-69 T 13-09-2016 THL1_RS11810 0dd21e1a94dd5e37c8fbcf378f3761fb 128 SUPERFAMILY SSF52833 21 128 6.26E-16 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS11810 0dd21e1a94dd5e37c8fbcf378f3761fb 128 Gene3D G3DSA:3.40.30.10 23 117 4.2E-5 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS15690 eb6d14857ec1ff507c8a7362a02fbc77 560 Gene3D G3DSA:3.40.605.10 91 326 5.0E-26 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS15690 eb6d14857ec1ff507c8a7362a02fbc77 560 Gene3D G3DSA:3.40.309.10 327 520 1.5E-29 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS15690 eb6d14857ec1ff507c8a7362a02fbc77 560 TIGRFAM TIGR02288 PaaN_2: phenylacetic acid degradation protein paaN 10 557 3.3E-295 T 13-09-2016 IPR011975 Phenylacetic acid degradation protein PaaN2 THL1_RS15690 eb6d14857ec1ff507c8a7362a02fbc77 560 SUPERFAMILY SSF53720 90 553 8.51E-60 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS15690 eb6d14857ec1ff507c8a7362a02fbc77 560 PANTHER PTHR11699 93 558 6.8E-100 T 13-09-2016 THL1_RS15690 eb6d14857ec1ff507c8a7362a02fbc77 560 PANTHER PTHR11699:SF165 93 558 6.8E-100 T 13-09-2016 THL1_RS15690 eb6d14857ec1ff507c8a7362a02fbc77 560 Pfam PF00171 Aldehyde dehydrogenase family 90 497 1.1E-33 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS20655 422358f42934338863abc31c2bd7052a 261 PANTHER PTHR11941 1 252 4.6E-73 T 13-09-2016 THL1_RS20655 422358f42934338863abc31c2bd7052a 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 256 8.7E-38 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS20655 422358f42934338863abc31c2bd7052a 261 SUPERFAMILY SSF52096 15 253 2.06E-60 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20655 422358f42934338863abc31c2bd7052a 261 PANTHER PTHR11941:SF76 1 252 4.6E-73 T 13-09-2016 THL1_RS20655 422358f42934338863abc31c2bd7052a 261 Gene3D G3DSA:3.90.226.10 16 253 1.6E-57 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS09055 d87a50e3e7b610acae232da2ffaa63cd 352 SUPERFAMILY SSF52733 5 348 1.12E-119 T 13-09-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 THL1_RS09055 d87a50e3e7b610acae232da2ffaa63cd 352 PANTHER PTHR21712 8 350 2.7E-123 T 13-09-2016 THL1_RS09055 d87a50e3e7b610acae232da2ffaa63cd 352 Gene3D G3DSA:1.10.1610.10 2 72 4.3E-32 T 13-09-2016 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 THL1_RS09055 d87a50e3e7b610acae232da2ffaa63cd 352 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 13 349 37.465 T 13-09-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 THL1_RS09055 d87a50e3e7b610acae232da2ffaa63cd 352 Pfam PF02277 Phosphoribosyltransferase 12 347 1.4E-131 T 13-09-2016 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 THL1_RS09055 d87a50e3e7b610acae232da2ffaa63cd 352 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 15 347 9.9E-134 T 13-09-2016 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00061 THL1_RS09055 d87a50e3e7b610acae232da2ffaa63cd 352 PANTHER PTHR21712:SF4 8 350 2.7E-123 T 13-09-2016 THL1_RS09055 d87a50e3e7b610acae232da2ffaa63cd 352 Gene3D G3DSA:3.40.50.10210 73 330 3.3E-108 T 13-09-2016 THL1_RS13115 7ed8c6d9d15f255f60fcdfb7c322d7a0 132 PANTHER PTHR30204:SF16 1 129 1.8E-24 T 13-09-2016 THL1_RS13115 7ed8c6d9d15f255f60fcdfb7c322d7a0 132 SMART SM00422 5 74 1.2E-25 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS13115 7ed8c6d9d15f255f60fcdfb7c322d7a0 132 Gene3D G3DSA:1.10.1660.10 60 130 7.8E-23 T 13-09-2016 THL1_RS13115 7ed8c6d9d15f255f60fcdfb7c322d7a0 132 SUPERFAMILY SSF46955 5 127 6.96E-30 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS13115 7ed8c6d9d15f255f60fcdfb7c322d7a0 132 PANTHER PTHR30204 1 129 1.8E-24 T 13-09-2016 THL1_RS13115 7ed8c6d9d15f255f60fcdfb7c322d7a0 132 Pfam PF09278 MerR, DNA binding 48 110 1.2E-17 T 13-09-2016 IPR015358 Transcription regulator MerR, DNA binding THL1_RS13115 7ed8c6d9d15f255f60fcdfb7c322d7a0 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 6.2E-16 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS13115 7ed8c6d9d15f255f60fcdfb7c322d7a0 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 6.2E-16 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS13115 7ed8c6d9d15f255f60fcdfb7c322d7a0 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 6.2E-16 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS13115 7ed8c6d9d15f255f60fcdfb7c322d7a0 132 Pfam PF00376 MerR family regulatory protein 6 43 9.1E-11 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS13115 7ed8c6d9d15f255f60fcdfb7c322d7a0 132 Gene3D G3DSA:1.10.1660.10 3 59 2.0E-23 T 13-09-2016 THL1_RS03105 fd72c061992fff755b0ee1a4bd94c991 103 SUPERFAMILY SSF81301 14 96 1.8E-14 T 13-09-2016 THL1_RS03105 fd72c061992fff755b0ee1a4bd94c991 103 Pfam PF01909 Nucleotidyltransferase domain 22 91 1.4E-9 T 13-09-2016 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THL1_RS03105 fd72c061992fff755b0ee1a4bd94c991 103 Gene3D G3DSA:3.30.460.10 6 103 4.6E-23 T 13-09-2016 THL1_RS08490 297101d8aed1bca7e86247a0482a3e6d 302 SUPERFAMILY SSF161098 26 289 1.44E-48 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS08490 297101d8aed1bca7e86247a0482a3e6d 302 PANTHER PTHR30193 25 302 1.5E-61 T 13-09-2016 THL1_RS08490 297101d8aed1bca7e86247a0482a3e6d 302 Gene3D G3DSA:1.10.3720.10 30 296 7.5E-40 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS08490 297101d8aed1bca7e86247a0482a3e6d 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 295 6.6E-13 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS04410 04cffa5041c5f48eebe36d66ec7d2403 316 PANTHER PTHR30346 1 307 4.0E-89 T 13-09-2016 THL1_RS04410 04cffa5041c5f48eebe36d66ec7d2403 316 SUPERFAMILY SSF53850 91 292 3.98E-39 T 13-09-2016 THL1_RS04410 04cffa5041c5f48eebe36d66ec7d2403 316 Gene3D G3DSA:1.10.10.10 1 84 1.9E-26 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS04410 04cffa5041c5f48eebe36d66ec7d2403 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.3E-20 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS04410 04cffa5041c5f48eebe36d66ec7d2403 316 Pfam PF03466 LysR substrate binding domain 88 290 7.9E-41 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS04410 04cffa5041c5f48eebe36d66ec7d2403 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.8E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS04410 04cffa5041c5f48eebe36d66ec7d2403 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.8E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS04410 04cffa5041c5f48eebe36d66ec7d2403 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.8E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS04410 04cffa5041c5f48eebe36d66ec7d2403 316 Gene3D G3DSA:3.40.190.10 88 175 4.9E-28 T 13-09-2016 THL1_RS04410 04cffa5041c5f48eebe36d66ec7d2403 316 Gene3D G3DSA:3.40.190.10 176 263 8.4E-29 T 13-09-2016 THL1_RS04410 04cffa5041c5f48eebe36d66ec7d2403 316 SUPERFAMILY SSF46785 1 85 1.02E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07760 ab5c331604d269db2601a0adc73295fe 125 SUPERFAMILY SSF88723 1 116 2.16E-18 T 13-09-2016 IPR029060 PIN domain-like THL1_RS07760 ab5c331604d269db2601a0adc73295fe 125 Pfam PF01850 PIN domain 3 115 1.3E-13 T 13-09-2016 IPR002716 PIN domain THL1_RS07760 ab5c331604d269db2601a0adc73295fe 125 PANTHER PTHR36173 2 118 6.1E-37 T 13-09-2016 THL1_RS07760 ab5c331604d269db2601a0adc73295fe 125 PANTHER PTHR36173:SF2 2 118 6.1E-37 T 13-09-2016 THL1_RS19985 2471588465b4ae6c28e9fc683c4bc69b 696 Gene3D G3DSA:3.40.720.10 314 607 4.4E-39 T 13-09-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THL1_RS19985 2471588465b4ae6c28e9fc683c4bc69b 696 PIRSF PIRSF005091 15 692 1.8E-132 T 13-09-2016 IPR012160 Lipoteichoic acid synthase-like KEGG: 00440+2.7.8.-|KEGG: 00513+2.7.8.-|KEGG: 00540+2.7.8.-|KEGG: 00564+2.7.8.-|KEGG: 00600+2.7.8.-|KEGG: 00770+2.7.8.-|UniPathway: UPA00556 THL1_RS19985 2471588465b4ae6c28e9fc683c4bc69b 696 PANTHER PTHR10342 276 658 1.2E-82 T 13-09-2016 THL1_RS19985 2471588465b4ae6c28e9fc683c4bc69b 696 PANTHER PTHR10342:SF236 276 658 1.2E-82 T 13-09-2016 THL1_RS19985 2471588465b4ae6c28e9fc683c4bc69b 696 SUPERFAMILY SSF53649 314 656 2.62E-62 T 13-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THL1_RS19985 2471588465b4ae6c28e9fc683c4bc69b 696 Pfam PF00884 Sulfatase 314 592 5.8E-47 T 13-09-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 THL1_RS00960 0a28a79bc86ed3a2adc226951468e78d 461 PANTHER PTHR20852:SF7 11 461 4.2E-145 T 13-09-2016 THL1_RS00960 0a28a79bc86ed3a2adc226951468e78d 461 SUPERFAMILY SSF54368 11 117 5.1E-16 T 13-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS00960 0a28a79bc86ed3a2adc226951468e78d 461 Gene3D G3DSA:3.30.590.10 126 447 6.1E-93 T 13-09-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 THL1_RS00960 0a28a79bc86ed3a2adc226951468e78d 461 Pfam PF00120 Glutamine synthetase, catalytic domain 123 457 2.3E-106 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS00960 0a28a79bc86ed3a2adc226951468e78d 461 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 259 274 - T 13-09-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS00960 0a28a79bc86ed3a2adc226951468e78d 461 SMART SM01230 122 379 7.9E-95 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS00960 0a28a79bc86ed3a2adc226951468e78d 461 PANTHER PTHR20852 11 461 4.2E-145 T 13-09-2016 THL1_RS00960 0a28a79bc86ed3a2adc226951468e78d 461 SUPERFAMILY SSF55931 124 459 1.96E-100 T 13-09-2016 THL1_RS00960 0a28a79bc86ed3a2adc226951468e78d 461 Gene3D G3DSA:3.10.20.70 11 125 7.2E-17 T 13-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS15830 797bd81daa73a9a48c6d92c3ea047818 207 TIGRFAM TIGR01323 nitrile_alph: nitrile hydratase, alpha subunit 12 197 7.3E-89 T 13-09-2016 IPR018141 Nitrile hydratase, alpha subunit GO:0006807|GO:0018822|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 THL1_RS15830 797bd81daa73a9a48c6d92c3ea047818 207 ProDom PD007559 HYDRATASE NITRILE ALPHA SUBUNIT LYASE CHAIN METAL-BINDING DIRECT SEQUENCING NITRILASE 19 195 9.0E-75 T 13-09-2016 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 THL1_RS15830 797bd81daa73a9a48c6d92c3ea047818 207 Pfam PF02979 Nitrile hydratase, alpha chain 14 193 8.2E-80 T 13-09-2016 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 THL1_RS15830 797bd81daa73a9a48c6d92c3ea047818 207 SUPERFAMILY SSF56209 9 195 8.63E-81 T 13-09-2016 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 THL1_RS15830 797bd81daa73a9a48c6d92c3ea047818 207 Gene3D G3DSA:3.90.330.10 8 198 1.1E-87 T 13-09-2016 IPR004232 Nitrile hydratase alpha /Thiocyanate hydrolase gamma GO:0003824|GO:0006807|GO:0046914 KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 THL1_RS15830 797bd81daa73a9a48c6d92c3ea047818 207 PIRSF PIRSF001426 1 201 4.3E-93 T 13-09-2016 IPR023900 Nitrile hydratase alpha subunit /Thiocyanate hydrolase gamma subunit KEGG: 00364+4.2.1.84|KEGG: 00380+4.2.1.84|KEGG: 00627+4.2.1.84|KEGG: 00643+4.2.1.84|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 THL1_RS08760 b6a23876a5ec3947309965bc5c8d715e 280 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 111 196 1.6E-17 T 13-09-2016 IPR032030 YscD, cytoplasmic domain THL1_RS08760 b6a23876a5ec3947309965bc5c8d715e 280 SUPERFAMILY SSF49879 86 200 1.13E-26 T 13-09-2016 IPR008984 SMAD/FHA domain GO:0005515 THL1_RS08760 b6a23876a5ec3947309965bc5c8d715e 280 Gene3D G3DSA:2.60.200.20 99 197 1.4E-24 T 13-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 THL1_RS08760 b6a23876a5ec3947309965bc5c8d715e 280 SMART SM00240 20 70 3.2E-7 T 13-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 THL1_RS08760 b6a23876a5ec3947309965bc5c8d715e 280 SMART SM00240 126 176 2.2E-8 T 13-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 THL1_RS08760 b6a23876a5ec3947309965bc5c8d715e 280 Pfam PF00498 FHA domain 22 85 2.1E-13 T 13-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 THL1_RS08760 b6a23876a5ec3947309965bc5c8d715e 280 Gene3D G3DSA:2.60.200.20 3 90 1.1E-19 T 13-09-2016 IPR000253 Forkhead-associated (FHA) domain GO:0005515 THL1_RS08760 b6a23876a5ec3947309965bc5c8d715e 280 SUPERFAMILY SSF49879 4 97 6.7E-20 T 13-09-2016 IPR008984 SMAD/FHA domain GO:0005515 THL1_RS23410 c6fed5ac766a27c64e150eeaa6667ad5 429 SMART SM00388 211 277 1.4E-13 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS23410 c6fed5ac766a27c64e150eeaa6667ad5 429 Gene3D G3DSA:3.30.565.10 286 421 2.0E-26 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS23410 c6fed5ac766a27c64e150eeaa6667ad5 429 Pfam PF00672 HAMP domain 137 206 4.9E-12 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS23410 c6fed5ac766a27c64e150eeaa6667ad5 429 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 323 421 2.5E-16 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS23410 c6fed5ac766a27c64e150eeaa6667ad5 429 SUPERFAMILY SSF55874 286 421 2.49E-27 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS23410 c6fed5ac766a27c64e150eeaa6667ad5 429 SMART SM00387 321 425 6.0E-24 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS23410 c6fed5ac766a27c64e150eeaa6667ad5 429 Pfam PF00512 His Kinase A (phospho-acceptor) domain 213 275 5.2E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS23410 c6fed5ac766a27c64e150eeaa6667ad5 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 381 1.3E-5 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS23410 c6fed5ac766a27c64e150eeaa6667ad5 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 1.3E-5 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS23410 c6fed5ac766a27c64e150eeaa6667ad5 429 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 403 1.3E-5 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS23410 c6fed5ac766a27c64e150eeaa6667ad5 429 Gene3D G3DSA:1.10.287.130 204 273 1.1E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS23410 c6fed5ac766a27c64e150eeaa6667ad5 429 PANTHER PTHR24423 150 421 2.7E-47 T 13-09-2016 THL1_RS23410 c6fed5ac766a27c64e150eeaa6667ad5 429 SMART SM00304 156 210 0.0038 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS23410 c6fed5ac766a27c64e150eeaa6667ad5 429 SUPERFAMILY SSF47384 194 276 2.75E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS11955 bc1d09c44c7ee479802a266b793af35e 330 PANTHER PTHR10366 2 328 2.9E-175 T 13-09-2016 THL1_RS11955 bc1d09c44c7ee479802a266b793af35e 330 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 317 8.9E-58 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11955 bc1d09c44c7ee479802a266b793af35e 330 PRINTS PR01713 Nucleotide sugar epimerase signature 216 231 4.6E-25 T 13-09-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 THL1_RS11955 bc1d09c44c7ee479802a266b793af35e 330 PRINTS PR01713 Nucleotide sugar epimerase signature 290 307 4.6E-25 T 13-09-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 THL1_RS11955 bc1d09c44c7ee479802a266b793af35e 330 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 4.6E-25 T 13-09-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 THL1_RS11955 bc1d09c44c7ee479802a266b793af35e 330 PRINTS PR01713 Nucleotide sugar epimerase signature 251 266 4.6E-25 T 13-09-2016 IPR008089 Nucleotide sugar epimerase GO:0005975|GO:0016857 THL1_RS11955 bc1d09c44c7ee479802a266b793af35e 330 Gene3D G3DSA:3.40.50.720 1 209 8.3E-74 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11955 bc1d09c44c7ee479802a266b793af35e 330 SUPERFAMILY SSF51735 1 328 1.19E-88 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11955 bc1d09c44c7ee479802a266b793af35e 330 Gene3D G3DSA:3.90.25.10 305 326 4.5E-13 T 13-09-2016 THL1_RS11955 bc1d09c44c7ee479802a266b793af35e 330 Gene3D G3DSA:3.90.25.10 210 238 4.5E-13 T 13-09-2016 THL1_RS11955 bc1d09c44c7ee479802a266b793af35e 330 PANTHER PTHR10366:SF77 2 328 2.9E-175 T 13-09-2016 THL1_RS18930 57dd55c60fd832d4b259249835584c13 178 SMART SM00448 2 114 5.2E-17 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS18930 57dd55c60fd832d4b259249835584c13 178 SUPERFAMILY SSF52172 1 147 1.15E-29 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS18930 57dd55c60fd832d4b259249835584c13 178 Pfam PF00072 Response regulator receiver domain 5 114 1.3E-19 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS18930 57dd55c60fd832d4b259249835584c13 178 PANTHER PTHR32071 2 132 8.4E-22 T 13-09-2016 THL1_RS18930 57dd55c60fd832d4b259249835584c13 178 PANTHER PTHR32071:SF39 2 132 8.4E-22 T 13-09-2016 THL1_RS18930 57dd55c60fd832d4b259249835584c13 178 Gene3D G3DSA:3.40.50.2300 1 134 1.4E-29 T 13-09-2016 THL1_RS24025 3a02f6b2009ec4fe2d1f4911b10f5b09 366 Gene3D G3DSA:3.10.20.30 270 366 9.9E-51 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS24025 3a02f6b2009ec4fe2d1f4911b10f5b09 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 2.4E-160 T 13-09-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 THL1_RS24025 3a02f6b2009ec4fe2d1f4911b10f5b09 366 SUPERFAMILY SSF81271 282 363 3.27E-37 T 13-09-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 THL1_RS24025 3a02f6b2009ec4fe2d1f4911b10f5b09 366 Pfam PF01926 50S ribosome-binding GTPase 5 119 5.6E-22 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS24025 3a02f6b2009ec4fe2d1f4911b10f5b09 366 Gene3D G3DSA:3.40.50.300 203 269 7.9E-42 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24025 3a02f6b2009ec4fe2d1f4911b10f5b09 366 Gene3D G3DSA:3.40.50.300 4 130 7.9E-42 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24025 3a02f6b2009ec4fe2d1f4911b10f5b09 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 1.2E-40 T 13-09-2016 IPR013029 Domain of unknown function DUF933 THL1_RS24025 3a02f6b2009ec4fe2d1f4911b10f5b09 366 PIRSF PIRSF006641 1 366 7.1E-159 T 13-09-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 THL1_RS24025 3a02f6b2009ec4fe2d1f4911b10f5b09 366 PANTHER PTHR23305 1 366 8.7E-211 T 13-09-2016 THL1_RS24025 3a02f6b2009ec4fe2d1f4911b10f5b09 366 PANTHER PTHR23305:SF12 1 366 8.7E-211 T 13-09-2016 THL1_RS24025 3a02f6b2009ec4fe2d1f4911b10f5b09 366 SUPERFAMILY SSF52540 3 304 2.16E-81 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24025 3a02f6b2009ec4fe2d1f4911b10f5b09 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 45.089 T 13-09-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 THL1_RS24025 3a02f6b2009ec4fe2d1f4911b10f5b09 366 Gene3D G3DSA:1.10.150.300 131 202 3.2E-26 T 13-09-2016 IPR023192 TGS-like domain THL1_RS24025 3a02f6b2009ec4fe2d1f4911b10f5b09 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.2E-32 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS24025 3a02f6b2009ec4fe2d1f4911b10f5b09 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.2E-32 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS24025 3a02f6b2009ec4fe2d1f4911b10f5b09 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.2E-32 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS24025 3a02f6b2009ec4fe2d1f4911b10f5b09 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.2E-32 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS21105 8a44c7a1c3088e3d8554a3939165bdb2 1155 PANTHER PTHR18968 345 752 4.7E-201 T 13-09-2016 THL1_RS21105 8a44c7a1c3088e3d8554a3939165bdb2 1155 SUPERFAMILY SSF52922 266 395 7.85E-8 T 13-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THL1_RS21105 8a44c7a1c3088e3d8554a3939165bdb2 1155 Gene3D G3DSA:3.40.920.10 717 917 2.0E-17 T 13-09-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 THL1_RS21105 8a44c7a1c3088e3d8554a3939165bdb2 1155 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 452 538 2.4E-6 T 13-09-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THL1_RS21105 8a44c7a1c3088e3d8554a3939165bdb2 1155 PANTHER PTHR18968:SF134 345 752 4.7E-201 T 13-09-2016 THL1_RS21105 8a44c7a1c3088e3d8554a3939165bdb2 1155 SUPERFAMILY SSF52518 20 201 5.89E-20 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS21105 8a44c7a1c3088e3d8554a3939165bdb2 1155 SUPERFAMILY SSF53323 716 960 1.44E-28 T 13-09-2016 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 THL1_RS21105 8a44c7a1c3088e3d8554a3939165bdb2 1155 SUPERFAMILY SSF52518 432 619 1.77E-13 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS21105 8a44c7a1c3088e3d8554a3939165bdb2 1155 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 724 910 1.1E-22 T 13-09-2016 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 THL1_RS21105 8a44c7a1c3088e3d8554a3939165bdb2 1155 Gene3D G3DSA:3.40.50.970 488 655 1.4E-11 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS19520 7032445531a17677ce2951d4b3c80e3e 445 SMART SM00962 225 417 3.1E-51 T 13-09-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 THL1_RS19520 7032445531a17677ce2951d4b3c80e3e 445 SMART SM00382 224 409 1.2E-6 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS19520 7032445531a17677ce2951d4b3c80e3e 445 PANTHER PTHR11564 148 414 1.3E-68 T 13-09-2016 THL1_RS19520 7032445531a17677ce2951d4b3c80e3e 445 Gene3D G3DSA:1.20.120.140 189 237 4.3E-6 T 13-09-2016 THL1_RS19520 7032445531a17677ce2951d4b3c80e3e 445 Gene3D G3DSA:3.40.50.300 238 414 5.6E-40 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS19520 7032445531a17677ce2951d4b3c80e3e 445 PANTHER PTHR11564:SF3 148 414 1.3E-68 T 13-09-2016 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 THL1_RS19520 7032445531a17677ce2951d4b3c80e3e 445 SUPERFAMILY SSF52540 222 415 3.07E-31 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS19520 7032445531a17677ce2951d4b3c80e3e 445 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 1 313 1.7E-75 T 13-09-2016 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 THL1_RS19520 7032445531a17677ce2951d4b3c80e3e 445 Pfam PF00448 SRP54-type protein, GTPase domain 227 415 8.7E-45 T 13-09-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 THL1_RS25740 995065af649050337cd41d5043b41e42 282 Pfam PF00924 Mechanosensitive ion channel 74 262 1.0E-35 T 13-09-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 THL1_RS25740 995065af649050337cd41d5043b41e42 282 SUPERFAMILY SSF50182 115 180 1.05E-15 T 13-09-2016 IPR010920 LSM domain THL1_RS25740 995065af649050337cd41d5043b41e42 282 PANTHER PTHR30221 1 282 5.3E-190 T 13-09-2016 THL1_RS25740 995065af649050337cd41d5043b41e42 282 Gene3D G3DSA:2.30.30.60 130 179 4.5E-17 T 13-09-2016 THL1_RS25740 995065af649050337cd41d5043b41e42 282 SUPERFAMILY SSF82861 29 112 1.83E-15 T 13-09-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 THL1_RS25740 995065af649050337cd41d5043b41e42 282 Gene3D G3DSA:3.30.70.100 184 262 4.1E-9 T 13-09-2016 THL1_RS25740 995065af649050337cd41d5043b41e42 282 SUPERFAMILY SSF82689 182 279 3.92E-15 T 13-09-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 THL1_RS25740 995065af649050337cd41d5043b41e42 282 PANTHER PTHR30221:SF3 1 282 5.3E-190 T 13-09-2016 THL1_RS02220 11b8a1e4cc032ca25304a25268f35ba9 560 Gene3D G3DSA:3.50.50.60 44 73 4.6E-11 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS02220 11b8a1e4cc032ca25304a25268f35ba9 560 Gene3D G3DSA:3.90.660.10 363 465 1.5E-25 T 13-09-2016 THL1_RS02220 11b8a1e4cc032ca25304a25268f35ba9 560 Gene3D G3DSA:3.90.660.10 74 149 1.5E-25 T 13-09-2016 THL1_RS02220 11b8a1e4cc032ca25304a25268f35ba9 560 PANTHER PTHR10742:SF277 13 536 1.2E-81 T 13-09-2016 THL1_RS02220 11b8a1e4cc032ca25304a25268f35ba9 560 PANTHER PTHR10742 13 536 1.2E-81 T 13-09-2016 THL1_RS02220 11b8a1e4cc032ca25304a25268f35ba9 560 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 431 446 8.4E-6 T 13-09-2016 THL1_RS02220 11b8a1e4cc032ca25304a25268f35ba9 560 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 47 69 8.4E-6 T 13-09-2016 THL1_RS02220 11b8a1e4cc032ca25304a25268f35ba9 560 SUPERFAMILY SSF54373 360 474 7.2E-25 T 13-09-2016 THL1_RS02220 11b8a1e4cc032ca25304a25268f35ba9 560 SUPERFAMILY SSF51905 45 374 1.25E-40 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS02220 11b8a1e4cc032ca25304a25268f35ba9 560 SUPERFAMILY SSF51905 496 536 1.25E-40 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS02220 11b8a1e4cc032ca25304a25268f35ba9 560 Gene3D G3DSA:3.50.50.60 499 541 1.5E-9 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS02220 11b8a1e4cc032ca25304a25268f35ba9 560 Gene3D G3DSA:3.50.50.60 239 359 1.5E-9 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS02220 11b8a1e4cc032ca25304a25268f35ba9 560 Pfam PF01593 Flavin containing amine oxidoreductase 55 531 1.3E-40 T 13-09-2016 IPR002937 Amine oxidase GO:0016491|GO:0055114 THL1_RS25980 a50d9186a0f8f5f91fe1d8f8a88724fa 271 Pfam PF00149 Calcineurin-like phosphoesterase 16 202 3.4E-15 T 13-09-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 THL1_RS25980 a50d9186a0f8f5f91fe1d8f8a88724fa 271 PANTHER PTHR12905:SF7 6 33 3.8E-80 T 13-09-2016 THL1_RS25980 a50d9186a0f8f5f91fe1d8f8a88724fa 271 PANTHER PTHR12905 6 33 3.8E-80 T 13-09-2016 THL1_RS25980 a50d9186a0f8f5f91fe1d8f8a88724fa 271 ProDom PD587589 PHOSPHODIESTERASE ICC METALLOPHOSPHOESTERASE CYCLIC REGULATOR LACZ AMP HYDROLASE 3'5'-CYCLIC-NUCLEOTIDE EXPRESSION 202 257 6.0E-19 T 13-09-2016 IPR013622 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, C-terminal KEGG: 00230+3.1.4.53 THL1_RS25980 a50d9186a0f8f5f91fe1d8f8a88724fa 271 PANTHER PTHR12905 49 271 3.8E-80 T 13-09-2016 THL1_RS25980 a50d9186a0f8f5f91fe1d8f8a88724fa 271 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 13 257 38.951 T 13-09-2016 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 THL1_RS25980 a50d9186a0f8f5f91fe1d8f8a88724fa 271 SUPERFAMILY SSF56300 15 255 9.42E-56 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS25980 a50d9186a0f8f5f91fe1d8f8a88724fa 271 Gene3D G3DSA:3.60.21.10 13 248 4.4E-32 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS25980 a50d9186a0f8f5f91fe1d8f8a88724fa 271 PANTHER PTHR12905:SF7 49 271 3.8E-80 T 13-09-2016 THL1_RS07065 db0ba10a3c3147086d3f09f0895e6d6f 252 Gene3D G3DSA:3.90.226.10 3 251 3.2E-62 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS07065 db0ba10a3c3147086d3f09f0895e6d6f 252 SUPERFAMILY SSF52096 2 252 1.06E-65 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS07065 db0ba10a3c3147086d3f09f0895e6d6f 252 PANTHER PTHR11941 7 250 8.8E-60 T 13-09-2016 THL1_RS07065 db0ba10a3c3147086d3f09f0895e6d6f 252 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 251 6.9E-43 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS16685 68b2eabe0adaf0f38a1c525f3c495d63 140 PANTHER PTHR30204 1 114 5.6E-30 T 13-09-2016 THL1_RS16685 68b2eabe0adaf0f38a1c525f3c495d63 140 PANTHER PTHR30204:SF18 1 114 5.6E-30 T 13-09-2016 THL1_RS16685 68b2eabe0adaf0f38a1c525f3c495d63 140 SMART SM00422 2 71 1.4E-30 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS16685 68b2eabe0adaf0f38a1c525f3c495d63 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 9.9E-14 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS16685 68b2eabe0adaf0f38a1c525f3c495d63 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 9.9E-14 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS16685 68b2eabe0adaf0f38a1c525f3c495d63 140 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 9.9E-14 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS16685 68b2eabe0adaf0f38a1c525f3c495d63 140 Pfam PF13411 MerR HTH family regulatory protein 3 68 1.3E-17 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS16685 68b2eabe0adaf0f38a1c525f3c495d63 140 Gene3D G3DSA:1.10.1660.10 57 131 2.3E-23 T 13-09-2016 THL1_RS16685 68b2eabe0adaf0f38a1c525f3c495d63 140 SUPERFAMILY SSF46955 2 115 1.28E-32 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS16685 68b2eabe0adaf0f38a1c525f3c495d63 140 Gene3D G3DSA:1.10.1660.10 1 56 3.4E-27 T 13-09-2016 THL1_RS01325 c6208ddea60b5aeb965e8c2baea42a72 459 Gene3D G3DSA:3.40.50.1100 46 150 6.9E-36 T 13-09-2016 THL1_RS01325 c6208ddea60b5aeb965e8c2baea42a72 459 Pfam PF00571 CBS domain 403 454 1.1E-6 T 13-09-2016 IPR000644 CBS domain THL1_RS01325 c6208ddea60b5aeb965e8c2baea42a72 459 Pfam PF00571 CBS domain 346 389 9.6E-8 T 13-09-2016 IPR000644 CBS domain THL1_RS01325 c6208ddea60b5aeb965e8c2baea42a72 459 PANTHER PTHR10314 1 365 1.1E-134 T 13-09-2016 THL1_RS01325 c6208ddea60b5aeb965e8c2baea42a72 459 Gene3D G3DSA:3.10.580.10 339 456 3.3E-19 T 13-09-2016 THL1_RS01325 c6208ddea60b5aeb965e8c2baea42a72 459 SUPERFAMILY SSF53686 4 323 9.95E-93 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS01325 c6208ddea60b5aeb965e8c2baea42a72 459 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 36 54 - T 13-09-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 THL1_RS01325 c6208ddea60b5aeb965e8c2baea42a72 459 SMART SM00116 346 393 1.6E-4 T 13-09-2016 IPR000644 CBS domain THL1_RS01325 c6208ddea60b5aeb965e8c2baea42a72 459 Gene3D G3DSA:3.40.50.1100 156 323 1.6E-61 T 13-09-2016 THL1_RS01325 c6208ddea60b5aeb965e8c2baea42a72 459 Gene3D G3DSA:3.40.50.1100 7 45 1.6E-61 T 13-09-2016 THL1_RS01325 c6208ddea60b5aeb965e8c2baea42a72 459 PANTHER PTHR10314:SF35 1 365 1.1E-134 T 13-09-2016 THL1_RS01325 c6208ddea60b5aeb965e8c2baea42a72 459 SUPERFAMILY SSF54631 336 455 3.41E-19 T 13-09-2016 THL1_RS01325 c6208ddea60b5aeb965e8c2baea42a72 459 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 13 305 3.4E-64 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS21180 cbfe8c82f90252d7f38dc738eca9aed0 448 SUPERFAMILY SSF55909 3 446 5.3E-203 T 13-09-2016 THL1_RS21180 cbfe8c82f90252d7f38dc738eca9aed0 448 PANTHER PTHR30420:SF2 2 447 3.7E-301 T 13-09-2016 THL1_RS21180 cbfe8c82f90252d7f38dc738eca9aed0 448 PANTHER PTHR30420 2 447 3.7E-301 T 13-09-2016 THL1_RS21180 cbfe8c82f90252d7f38dc738eca9aed0 448 TIGRFAM TIGR03241 arg_catab_astB: succinylarginine dihydrolase 3 446 1.5E-241 T 13-09-2016 IPR007079 Succinylarginine dihydrolase GO:0006525|GO:0009015 KEGG: 00330+3.5.3.23|UniPathway: UPA00185 THL1_RS21180 cbfe8c82f90252d7f38dc738eca9aed0 448 Gene3D G3DSA:3.75.10.20 2 447 1.6E-222 T 13-09-2016 IPR007079 Succinylarginine dihydrolase GO:0006525|GO:0009015 KEGG: 00330+3.5.3.23|UniPathway: UPA00185 THL1_RS21180 cbfe8c82f90252d7f38dc738eca9aed0 448 Hamap MF_01172 N-succinylarginine dihydrolase [astB]. 1 447 59.565 T 13-09-2016 IPR007079 Succinylarginine dihydrolase GO:0006525|GO:0009015 KEGG: 00330+3.5.3.23|UniPathway: UPA00185 THL1_RS21180 cbfe8c82f90252d7f38dc738eca9aed0 448 Pfam PF04996 Succinylarginine dihydrolase 3 446 2.0E-220 T 13-09-2016 IPR007079 Succinylarginine dihydrolase GO:0006525|GO:0009015 KEGG: 00330+3.5.3.23|UniPathway: UPA00185 THL1_RS01430 750137a829536bce739317ff876b27fc 349 PANTHER PTHR24220 6 296 2.7E-143 T 13-09-2016 THL1_RS01430 750137a829536bce739317ff876b27fc 349 SUPERFAMILY SSF52540 5 246 7.87E-85 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01430 750137a829536bce739317ff876b27fc 349 Gene3D G3DSA:3.40.50.300 2 241 9.8E-79 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01430 750137a829536bce739317ff876b27fc 349 SUPERFAMILY SSF50331 241 347 6.8E-13 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS01430 750137a829536bce739317ff876b27fc 349 PANTHER PTHR24220:SF150 6 296 2.7E-143 T 13-09-2016 THL1_RS01430 750137a829536bce739317ff876b27fc 349 SMART SM00382 33 216 1.2E-19 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS01430 750137a829536bce739317ff876b27fc 349 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 39 340 9.5E-110 T 13-09-2016 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 THL1_RS01430 750137a829536bce739317ff876b27fc 349 Pfam PF00005 ABC transporter 24 165 5.3E-34 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS01430 750137a829536bce739317ff876b27fc 349 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS01430 750137a829536bce739317ff876b27fc 349 ProSitePatterns PS00211 ABC transporters family signature. 329 343 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS01430 750137a829536bce739317ff876b27fc 349 Pfam PF08402 TOBE domain 274 347 9.9E-13 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS17905 ade863a9f95c32c01989019ff51e170c 254 SUPERFAMILY SSF53335 63 178 5.98E-15 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS17905 ade863a9f95c32c01989019ff51e170c 254 Gene3D G3DSA:3.40.50.150 89 217 6.5E-10 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS17905 ade863a9f95c32c01989019ff51e170c 254 Pfam PF08241 Methyltransferase domain 78 131 3.9E-7 T 13-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 THL1_RS10680 c616f44e1bd77d3f3e52caa59bd666e7 488 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 139 299 4.1E-36 T 13-09-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS10680 c616f44e1bd77d3f3e52caa59bd666e7 488 SMART SM00846 138 299 4.0E-53 T 13-09-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS10680 c616f44e1bd77d3f3e52caa59bd666e7 488 PANTHER PTHR10836 126 486 8.6E-242 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS10680 c616f44e1bd77d3f3e52caa59bd666e7 488 SUPERFAMILY SSF55347 299 462 1.1E-55 T 13-09-2016 THL1_RS10680 c616f44e1bd77d3f3e52caa59bd666e7 488 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 297 304 - T 13-09-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS10680 c616f44e1bd77d3f3e52caa59bd666e7 488 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 304 461 5.1E-48 T 13-09-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS10680 c616f44e1bd77d3f3e52caa59bd666e7 488 Gene3D G3DSA:3.40.50.720 139 307 1.3E-48 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10680 c616f44e1bd77d3f3e52caa59bd666e7 488 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 140 473 1.7E-111 T 13-09-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS10680 c616f44e1bd77d3f3e52caa59bd666e7 488 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 320 336 1.6E-18 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS10680 c616f44e1bd77d3f3e52caa59bd666e7 488 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 418 433 1.6E-18 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS10680 c616f44e1bd77d3f3e52caa59bd666e7 488 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 376 393 1.6E-18 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS10680 c616f44e1bd77d3f3e52caa59bd666e7 488 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 257 270 1.6E-18 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS10680 c616f44e1bd77d3f3e52caa59bd666e7 488 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 293 311 1.6E-18 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS10680 c616f44e1bd77d3f3e52caa59bd666e7 488 SUPERFAMILY SSF51735 139 315 1.22E-44 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10680 c616f44e1bd77d3f3e52caa59bd666e7 488 PANTHER PTHR10836:SF35 126 486 8.6E-242 T 13-09-2016 THL1_RS10680 c616f44e1bd77d3f3e52caa59bd666e7 488 Gene3D G3DSA:3.30.360.10 308 463 3.9E-58 T 13-09-2016 THL1_RS02915 e27fceef040f660c4cc362c8b85144b8 265 PANTHER PTHR32552 15 261 3.4E-13 T 13-09-2016 THL1_RS02915 e27fceef040f660c4cc362c8b85144b8 265 Gene3D G3DSA:3.30.420.10 92 255 2.5E-27 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS02915 e27fceef040f660c4cc362c8b85144b8 265 SUPERFAMILY SSF53098 93 259 1.11E-28 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS02915 e27fceef040f660c4cc362c8b85144b8 265 Pfam PF13276 HTH-like domain 25 81 2.1E-12 T 13-09-2016 IPR025948 HTH-like domain THL1_RS02915 e27fceef040f660c4cc362c8b85144b8 265 Pfam PF00665 Integrase core domain 98 216 2.0E-23 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS04155 0693d68aca754c951602337276531ae8 203 Gene3D G3DSA:3.40.50.150 32 183 1.6E-27 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS04155 0693d68aca754c951602337276531ae8 203 SUPERFAMILY SSF53335 28 185 6.19E-32 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS04155 0693d68aca754c951602337276531ae8 203 Pfam PF08241 Methyltransferase domain 38 133 7.4E-19 T 13-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 THL1_RS04155 0693d68aca754c951602337276531ae8 203 PANTHER PTHR10108 33 180 6.8E-26 T 13-09-2016 THL1_RS04155 0693d68aca754c951602337276531ae8 203 PANTHER PTHR10108:SF714 33 180 6.8E-26 T 13-09-2016 THL1_RS05335 84f035625c7982d759f375e2822087ed 173 Gene3D G3DSA:1.10.60.30 23 95 2.6E-26 T 13-09-2016 IPR023153 PSPTO4464-like domain THL1_RS05335 84f035625c7982d759f375e2822087ed 173 SUPERFAMILY SSF158710 23 165 1.44E-50 T 13-09-2016 THL1_RS05335 84f035625c7982d759f375e2822087ed 173 PANTHER PTHR38101:SF1 6 173 1.4E-71 T 13-09-2016 THL1_RS05335 84f035625c7982d759f375e2822087ed 173 Pfam PF04751 Protein of unknown function (DUF615) 12 163 3.3E-54 T 13-09-2016 IPR006839 Ribosome-associated, YjgA THL1_RS05335 84f035625c7982d759f375e2822087ed 173 Hamap MF_00765 UPF0307 protein YjgA [yjgA]. 2 167 21.321 T 13-09-2016 IPR006839 Ribosome-associated, YjgA THL1_RS05335 84f035625c7982d759f375e2822087ed 173 PIRSF PIRSF016183 2 171 5.4E-65 T 13-09-2016 IPR006839 Ribosome-associated, YjgA THL1_RS05335 84f035625c7982d759f375e2822087ed 173 Gene3D G3DSA:1.10.60.30 99 169 9.3E-30 T 13-09-2016 IPR023153 PSPTO4464-like domain THL1_RS05335 84f035625c7982d759f375e2822087ed 173 PANTHER PTHR38101 6 173 1.4E-71 T 13-09-2016 THL1_RS19115 7978764999e240b68ac11dc2d3f1d3e2 192 SUPERFAMILY SSF50475 4 185 4.12E-39 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS19115 7978764999e240b68ac11dc2d3f1d3e2 192 PANTHER PTHR30466 5 185 5.1E-24 T 13-09-2016 THL1_RS19115 7978764999e240b68ac11dc2d3f1d3e2 192 SMART SM00903 15 157 6.9E-18 T 13-09-2016 IPR002563 Flavin reductase like domain GO:0010181 THL1_RS19115 7978764999e240b68ac11dc2d3f1d3e2 192 Gene3D G3DSA:2.30.110.10 4 185 3.0E-49 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS19115 7978764999e240b68ac11dc2d3f1d3e2 192 Pfam PF01613 Flavin reductase like domain 20 153 6.9E-15 T 13-09-2016 IPR002563 Flavin reductase like domain GO:0010181 THL1_RS19115 7978764999e240b68ac11dc2d3f1d3e2 192 PANTHER PTHR30466:SF6 5 185 5.1E-24 T 13-09-2016 THL1_RS10250 e9a55624a272f35b2ef5d5f07f64e8a8 295 PANTHER PTHR20275 4 291 2.9E-104 T 13-09-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 THL1_RS10250 e9a55624a272f35b2ef5d5f07f64e8a8 295 Gene3D G3DSA:2.60.200.30 150 261 3.3E-44 T 13-09-2016 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 THL1_RS10250 e9a55624a272f35b2ef5d5f07f64e8a8 295 Pfam PF01513 ATP-NAD kinase 6 271 7.8E-70 T 13-09-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 THL1_RS10250 e9a55624a272f35b2ef5d5f07f64e8a8 295 Hamap MF_00361 NAD kinase [nadK]. 5 287 34.383 T 13-09-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 THL1_RS10250 e9a55624a272f35b2ef5d5f07f64e8a8 295 Gene3D G3DSA:3.40.50.10330 3 149 1.8E-42 T 13-09-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 THL1_RS10250 e9a55624a272f35b2ef5d5f07f64e8a8 295 SUPERFAMILY SSF111331 6 289 2.62E-90 T 13-09-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain THL1_RS17810 4b2f1e339fd26fe4bca94ecadc1955b9 356 Pfam PF01636 Phosphotransferase enzyme family 38 274 1.6E-44 T 13-09-2016 IPR002575 Aminoglycoside phosphotransferase THL1_RS17810 4b2f1e339fd26fe4bca94ecadc1955b9 356 PANTHER PTHR21310:SF14 15 265 9.7E-15 T 13-09-2016 THL1_RS17810 4b2f1e339fd26fe4bca94ecadc1955b9 356 PANTHER PTHR21310 15 265 9.7E-15 T 13-09-2016 THL1_RS17810 4b2f1e339fd26fe4bca94ecadc1955b9 356 Gene3D G3DSA:3.90.1200.10 128 343 4.6E-36 T 13-09-2016 THL1_RS17810 4b2f1e339fd26fe4bca94ecadc1955b9 356 SUPERFAMILY SSF56112 17 340 3.12E-58 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 Gene3D G3DSA:2.40.30.10 331 430 1.1E-27 T 13-09-2016 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 PRINTS PR00410 Phenol hydroxylase reductase family signature 362 374 3.2E-6 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 PRINTS PR00410 Phenol hydroxylase reductase family signature 439 458 3.2E-6 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 PRINTS PR00410 Phenol hydroxylase reductase family signature 539 547 3.2E-6 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 PRINTS PR00410 Phenol hydroxylase reductase family signature 423 432 3.2E-6 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 SUPERFAMILY SSF50475 179 276 1.46E-5 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 SUPERFAMILY SSF63380 330 428 2.04E-25 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 SUPERFAMILY SSF52343 431 574 1.57E-33 T 13-09-2016 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 Pfam PF00175 Oxidoreductase NAD-binding domain 440 552 4.9E-10 T 13-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 Gene3D G3DSA:2.30.110.10 172 293 7.0E-7 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 Gene3D G3DSA:2.30.110.10 35 131 6.6E-5 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 SUPERFAMILY SSF50475 38 133 5.05E-5 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 632 640 - T 13-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 SUPERFAMILY SSF54292 562 672 4.72E-18 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 Gene3D G3DSA:3.10.20.30 569 672 1.8E-20 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 Pfam PF00970 Oxidoreductase FAD-binding domain 336 428 2.9E-12 T 13-09-2016 IPR008333 Oxidoreductase, FAD-binding domain THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 41 133 2.6E-9 T 13-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 175 269 8.5E-10 T 13-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 PANTHER PTHR30212:SF3 8 300 1.4E-62 T 13-09-2016 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 612 671 8.3E-9 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 Gene3D G3DSA:3.40.50.80 432 568 3.7E-32 T 13-09-2016 THL1_RS11085 4a096bc48de5613778640446d5c28bd5 685 PANTHER PTHR30212 8 300 1.4E-62 T 13-09-2016 THL1_RS05655 58f6158d21d92514be57d2f230490096 287 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 47 271 23.556 T 13-09-2016 IPR026579 Cell division protein FtsQ GO:0000917 THL1_RS05655 58f6158d21d92514be57d2f230490096 287 Pfam PF08478 POTRA domain, FtsQ-type 78 146 1.2E-18 T 13-09-2016 IPR013685 Polypeptide-transport-associated, FtsQ-type THL1_RS05655 58f6158d21d92514be57d2f230490096 287 Pfam PF03799 Cell division protein FtsQ 150 263 2.4E-22 T 13-09-2016 IPR005548 Cell division protein FtsQ/DivIB THL1_RS05655 58f6158d21d92514be57d2f230490096 287 PANTHER PTHR35851:SF1 2 287 7.6E-67 T 13-09-2016 THL1_RS05655 58f6158d21d92514be57d2f230490096 287 PANTHER PTHR35851 2 287 7.6E-67 T 13-09-2016 THL1_RS17735 6658548b67030d96eca62ab9c93f0a63 194 PANTHER PTHR10072 150 191 9.9E-82 T 13-09-2016 THL1_RS17735 6658548b67030d96eca62ab9c93f0a63 194 PANTHER PTHR10072 1 100 9.9E-82 T 13-09-2016 THL1_RS17735 6658548b67030d96eca62ab9c93f0a63 194 SUPERFAMILY SSF117916 98 188 1.83E-25 T 13-09-2016 THL1_RS17735 6658548b67030d96eca62ab9c93f0a63 194 SUPERFAMILY SSF89360 3 100 1.41E-18 T 13-09-2016 IPR000361 FeS cluster biogenesis THL1_RS17735 6658548b67030d96eca62ab9c93f0a63 194 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 121 180 5.0E-26 T 13-09-2016 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 THL1_RS17735 6658548b67030d96eca62ab9c93f0a63 194 Gene3D G3DSA:2.60.300.12 2 97 4.0E-14 T 13-09-2016 IPR000361 FeS cluster biogenesis THL1_RS17735 6658548b67030d96eca62ab9c93f0a63 194 Hamap MF_01637 Fe/S biogenesis protein NfuA [nfuA]. 3 194 42.02 T 13-09-2016 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 THL1_RS17735 6658548b67030d96eca62ab9c93f0a63 194 Pfam PF01106 NifU-like domain 114 180 1.6E-21 T 13-09-2016 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 THL1_RS17735 6658548b67030d96eca62ab9c93f0a63 194 Pfam PF01521 Iron-sulphur cluster biosynthesis 4 100 1.4E-8 T 13-09-2016 IPR000361 FeS cluster biogenesis THL1_RS17735 6658548b67030d96eca62ab9c93f0a63 194 PANTHER PTHR10072:SF37 1 100 9.9E-82 T 13-09-2016 THL1_RS17735 6658548b67030d96eca62ab9c93f0a63 194 PANTHER PTHR10072:SF37 150 191 9.9E-82 T 13-09-2016 THL1_RS17735 6658548b67030d96eca62ab9c93f0a63 194 TIGRFAM TIGR03341 YhgI_GntY: IscR-regulated protein YhgI 4 194 8.2E-94 T 13-09-2016 IPR017726 Fe/S biogenesis protein NfuA GO:0016226|GO:0051539|GO:0051604 THL1_RS15875 7c3831df076dc5fb535ffcc73fc8d8d7 132 Gene3D G3DSA:1.10.1660.10 58 121 2.7E-16 T 13-09-2016 THL1_RS15875 7c3831df076dc5fb535ffcc73fc8d8d7 132 SMART SM00422 5 72 2.3E-19 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS15875 7c3831df076dc5fb535ffcc73fc8d8d7 132 ProSitePatterns PS00552 MerR-type HTH domain signature. 8 30 - T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS15875 7c3831df076dc5fb535ffcc73fc8d8d7 132 SUPERFAMILY SSF46955 5 117 1.06E-24 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS15875 7c3831df076dc5fb535ffcc73fc8d8d7 132 PANTHER PTHR30204:SF1 1 117 1.1E-22 T 13-09-2016 THL1_RS15875 7c3831df076dc5fb535ffcc73fc8d8d7 132 Gene3D G3DSA:1.10.1660.10 3 57 1.9E-21 T 13-09-2016 THL1_RS15875 7c3831df076dc5fb535ffcc73fc8d8d7 132 PANTHER PTHR30204 1 117 1.1E-22 T 13-09-2016 THL1_RS15875 7c3831df076dc5fb535ffcc73fc8d8d7 132 Pfam PF13411 MerR HTH family regulatory protein 5 70 1.1E-17 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS12240 f73772359d66ec7a5986c4cac0999ef1 487 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 9 473 3.5E-125 T 13-09-2016 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 THL1_RS12240 f73772359d66ec7a5986c4cac0999ef1 487 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 6 474 17.598 T 13-09-2016 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 THL1_RS12240 f73772359d66ec7a5986c4cac0999ef1 487 Pfam PF00361 Proton-conducting membrane transporter 127 419 2.8E-78 T 13-09-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 THL1_RS12240 f73772359d66ec7a5986c4cac0999ef1 487 PANTHER PTHR22773:SF41 1 480 5.3E-168 T 13-09-2016 THL1_RS12240 f73772359d66ec7a5986c4cac0999ef1 487 PANTHER PTHR22773 1 480 5.3E-168 T 13-09-2016 THL1_RS01710 a1c2d1e348dba3be134384a41ae73835 459 Pfam PF00270 DEAD/DEAH box helicase 28 191 1.8E-45 T 13-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THL1_RS01710 a1c2d1e348dba3be134384a41ae73835 459 Pfam PF03880 DbpA RNA binding domain 387 457 1.1E-25 T 13-09-2016 IPR005580 DbpA, RNA-binding domain THL1_RS01710 a1c2d1e348dba3be134384a41ae73835 459 Gene3D G3DSA:3.40.50.300 3 207 6.2E-74 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01710 a1c2d1e348dba3be134384a41ae73835 459 SMART SM00487 23 220 6.2E-56 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS01710 a1c2d1e348dba3be134384a41ae73835 459 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 13-09-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site THL1_RS01710 a1c2d1e348dba3be134384a41ae73835 459 Gene3D G3DSA:3.40.50.300 208 365 1.5E-44 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01710 a1c2d1e348dba3be134384a41ae73835 459 SUPERFAMILY SSF52540 72 356 1.09E-69 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01710 a1c2d1e348dba3be134384a41ae73835 459 SMART SM00490 256 337 6.1E-28 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS01710 a1c2d1e348dba3be134384a41ae73835 459 PANTHER PTHR24031:SF180 1 459 1.1E-252 T 13-09-2016 THL1_RS01710 a1c2d1e348dba3be134384a41ae73835 459 Pfam PF00271 Helicase conserved C-terminal domain 229 337 1.2E-24 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS01710 a1c2d1e348dba3be134384a41ae73835 459 PANTHER PTHR24031 1 459 1.1E-252 T 13-09-2016 THL1_RS13530 e070ab1709dd0c38beaa888a24272a06 641 SUPERFAMILY SSF52540 325 624 1.5E-59 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS13530 e070ab1709dd0c38beaa888a24272a06 641 SUPERFAMILY SSF52540 100 231 1.5E-59 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS13530 e070ab1709dd0c38beaa888a24272a06 641 Gene3D G3DSA:3.40.50.300 454 627 5.0E-8 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS13530 e070ab1709dd0c38beaa888a24272a06 641 PANTHER PTHR11070 68 271 1.9E-59 T 13-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 THL1_RS13530 e070ab1709dd0c38beaa888a24272a06 641 PANTHER PTHR11070 300 618 1.9E-59 T 13-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 THL1_RS13530 e070ab1709dd0c38beaa888a24272a06 641 Pfam PF00580 UvrD/REP helicase N-terminal domain 105 175 1.5E-9 T 13-09-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 THL1_RS13530 e070ab1709dd0c38beaa888a24272a06 641 Pfam PF00580 UvrD/REP helicase N-terminal domain 323 439 6.2E-17 T 13-09-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 THL1_RS13530 e070ab1709dd0c38beaa888a24272a06 641 Gene3D G3DSA:3.40.50.300 335 441 5.0E-47 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS13530 e070ab1709dd0c38beaa888a24272a06 641 Gene3D G3DSA:3.40.50.300 102 246 5.0E-47 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28240 adc7022cdb2a17f4c88f7b539f8bd223 441 PANTHER PTHR30217:SF6 234 428 1.5E-218 T 13-09-2016 THL1_RS28240 adc7022cdb2a17f4c88f7b539f8bd223 441 ProSitePatterns PS01276 Peptidase family U32 signature. 162 180 - T 13-09-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS28240 adc7022cdb2a17f4c88f7b539f8bd223 441 Pfam PF16325 Peptidase family U32 C-terminal domain 347 428 8.7E-16 T 13-09-2016 IPR032525 Peptidase family U32, C-terminal KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS28240 adc7022cdb2a17f4c88f7b539f8bd223 441 Pfam PF01136 Peptidase family U32 76 330 3.5E-96 T 13-09-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS28240 adc7022cdb2a17f4c88f7b539f8bd223 441 PANTHER PTHR30217 234 428 1.5E-218 T 13-09-2016 THL1_RS28240 adc7022cdb2a17f4c88f7b539f8bd223 441 PANTHER PTHR30217 1 206 1.5E-218 T 13-09-2016 THL1_RS28240 adc7022cdb2a17f4c88f7b539f8bd223 441 PANTHER PTHR30217:SF6 1 206 1.5E-218 T 13-09-2016 THL1_RS19505 e4c78227121c01464a9c7be2d9dee10d 128 Gene3D G3DSA:3.40.50.2300 3 125 1.9E-39 T 13-09-2016 THL1_RS19505 e4c78227121c01464a9c7be2d9dee10d 128 SMART SM00448 5 119 4.9E-35 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS19505 e4c78227121c01464a9c7be2d9dee10d 128 Pfam PF00072 Response regulator receiver domain 7 120 3.5E-31 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS19505 e4c78227121c01464a9c7be2d9dee10d 128 SUPERFAMILY SSF52172 3 125 1.27E-37 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS19505 e4c78227121c01464a9c7be2d9dee10d 128 PANTHER PTHR26402 5 125 9.4E-43 T 13-09-2016 THL1_RS11980 c9fddece4d4bbe188271eaf9f4a9254e 525 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 25 513 1.2E-242 T 13-09-2016 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254|UniPathway: UPA00223 THL1_RS11980 c9fddece4d4bbe188271eaf9f4a9254e 525 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 26 510 9.1E-217 T 13-09-2016 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254|UniPathway: UPA00223 THL1_RS11980 c9fddece4d4bbe188271eaf9f4a9254e 525 PANTHER PTHR13847:SF214 21 466 1.5E-213 T 13-09-2016 THL1_RS11980 c9fddece4d4bbe188271eaf9f4a9254e 525 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 22 513 54.464 T 13-09-2016 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254|UniPathway: UPA00223 THL1_RS11980 c9fddece4d4bbe188271eaf9f4a9254e 525 PANTHER PTHR13847 21 466 1.5E-213 T 13-09-2016 THL1_RS11980 c9fddece4d4bbe188271eaf9f4a9254e 525 Gene3D G3DSA:3.50.50.60 24 117 1.4E-18 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS11980 c9fddece4d4bbe188271eaf9f4a9254e 525 Gene3D G3DSA:3.50.50.60 167 349 1.4E-18 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS11980 c9fddece4d4bbe188271eaf9f4a9254e 525 SUPERFAMILY SSF51905 20 349 2.78E-25 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27790 b63d4941b1c35103404e1a8f9540d1b1 497 Gene3D G3DSA:3.40.605.10 19 280 1.8E-88 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS27790 b63d4941b1c35103404e1a8f9540d1b1 497 PANTHER PTHR11699:SF210 1 497 0.0 T 13-09-2016 THL1_RS27790 b63d4941b1c35103404e1a8f9540d1b1 497 Pfam PF00171 Aldehyde dehydrogenase family 33 492 1.5E-165 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS27790 b63d4941b1c35103404e1a8f9540d1b1 497 PANTHER PTHR11699 1 497 0.0 T 13-09-2016 THL1_RS27790 b63d4941b1c35103404e1a8f9540d1b1 497 Gene3D G3DSA:3.40.309.10 281 468 7.5E-71 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS27790 b63d4941b1c35103404e1a8f9540d1b1 497 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 266 273 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS27790 b63d4941b1c35103404e1a8f9540d1b1 497 SUPERFAMILY SSF53720 12 496 1.57E-162 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS27790 b63d4941b1c35103404e1a8f9540d1b1 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS06790 8f68f0c58eb9a65a81f530a5d7d00dca 248 PANTHER PTHR34108:SF1 3 248 2.0E-72 T 13-09-2016 THL1_RS06790 8f68f0c58eb9a65a81f530a5d7d00dca 248 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 12 248 27.644 T 13-09-2016 IPR013033 Septum formation inhibitor MinC GO:0000917|GO:0051726 THL1_RS06790 8f68f0c58eb9a65a81f530a5d7d00dca 248 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 7 112 5.4E-27 T 13-09-2016 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 THL1_RS06790 8f68f0c58eb9a65a81f530a5d7d00dca 248 PANTHER PTHR34108 3 248 2.0E-72 T 13-09-2016 THL1_RS06790 8f68f0c58eb9a65a81f530a5d7d00dca 248 SUPERFAMILY SSF63848 142 247 9.55E-30 T 13-09-2016 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 THL1_RS06790 8f68f0c58eb9a65a81f530a5d7d00dca 248 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 12 248 3.8E-88 T 13-09-2016 IPR013033 Septum formation inhibitor MinC GO:0000917|GO:0051726 THL1_RS06790 8f68f0c58eb9a65a81f530a5d7d00dca 248 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 144 245 9.4E-30 T 13-09-2016 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 THL1_RS06790 8f68f0c58eb9a65a81f530a5d7d00dca 248 Gene3D G3DSA:2.160.20.70 128 248 3.0E-37 T 13-09-2016 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 THL1_RS14255 5127bca6437cd6b8a7db905eea221d5e 506 SUPERFAMILY SSF53720 12 497 2.23E-161 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS14255 5127bca6437cd6b8a7db905eea221d5e 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 294 305 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS14255 5127bca6437cd6b8a7db905eea221d5e 506 Pfam PF00171 Aldehyde dehydrogenase family 34 493 4.1E-164 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS14255 5127bca6437cd6b8a7db905eea221d5e 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS14255 5127bca6437cd6b8a7db905eea221d5e 506 PANTHER PTHR11699 1 506 0.0 T 13-09-2016 THL1_RS14255 5127bca6437cd6b8a7db905eea221d5e 506 Gene3D G3DSA:3.40.605.10 18 269 1.9E-93 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS14255 5127bca6437cd6b8a7db905eea221d5e 506 Gene3D G3DSA:3.40.309.10 270 469 5.2E-61 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS14255 5127bca6437cd6b8a7db905eea221d5e 506 PANTHER PTHR11699:SF97 1 506 0.0 T 13-09-2016 THL1_RS20725 a54d1b2b8d91978e84b21bf95d2a8e60 551 SUPERFAMILY SSF52540 1 311 2.01E-11 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS20725 a54d1b2b8d91978e84b21bf95d2a8e60 551 Gene3D G3DSA:3.40.50.300 1 325 8.4E-17 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS20725 a54d1b2b8d91978e84b21bf95d2a8e60 551 Pfam PF13175 AAA ATPase domain 1 307 2.1E-23 T 13-09-2016 THL1_RS18715 c3eeccd08f9a367986801bf34de250f5 380 SUPERFAMILY SSF52283 4 101 1.55E-17 T 13-09-2016 THL1_RS18715 c3eeccd08f9a367986801bf34de250f5 380 SUPERFAMILY SSF51735 91 256 5.3E-33 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18715 c3eeccd08f9a367986801bf34de250f5 380 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 196 212 - T 13-09-2016 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site THL1_RS18715 c3eeccd08f9a367986801bf34de250f5 380 Gene3D G3DSA:3.40.50.720 99 257 6.0E-35 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18715 c3eeccd08f9a367986801bf34de250f5 380 Pfam PF11890 Domain of unknown function (DUF3410) 288 376 5.4E-24 T 13-09-2016 IPR024531 Erythronate-4-phosphate dehydrogenase, dimerisation domain GO:0046983 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181|UniPathway: UPA00244 THL1_RS18715 c3eeccd08f9a367986801bf34de250f5 380 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 32 271 5.6E-15 T 13-09-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 THL1_RS18715 c3eeccd08f9a367986801bf34de250f5 380 PANTHER PTHR10996:SF111 1 330 1.6E-139 T 13-09-2016 THL1_RS18715 c3eeccd08f9a367986801bf34de250f5 380 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 255 2.3E-30 T 13-09-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 THL1_RS18715 c3eeccd08f9a367986801bf34de250f5 380 PANTHER PTHR10996 1 330 1.6E-139 T 13-09-2016 THL1_RS18715 c3eeccd08f9a367986801bf34de250f5 380 Hamap MF_01825 Erythronate-4-phosphate dehydrogenase [pdxB]. 1 362 43.986 T 13-09-2016 IPR020921 Erythronate-4-phosphate dehydrogenase GO:0005737|GO:0008615|GO:0033711|GO:0055114 KEGG: 00260+1.1.1.29|KEGG: 00630+1.1.1.29|KEGG: 00680+1.1.1.29|KEGG: 00750+1.1.1.290|MetaCyc: PWY-181|UniPathway: UPA00244 THL1_RS18715 c3eeccd08f9a367986801bf34de250f5 380 Gene3D G3DSA:3.40.50.720 1 98 2.2E-18 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS03260 3b331d4f274ed725b0e5069aa11cf3fc 201 SUPERFAMILY SSF51182 64 200 1.04E-27 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS03260 3b331d4f274ed725b0e5069aa11cf3fc 201 Pfam PF07883 Cupin domain 130 195 5.6E-19 T 13-09-2016 IPR013096 Cupin 2, conserved barrel THL1_RS03260 3b331d4f274ed725b0e5069aa11cf3fc 201 PANTHER PTHR10245 21 201 5.0E-35 T 13-09-2016 THL1_RS03260 3b331d4f274ed725b0e5069aa11cf3fc 201 Gene3D G3DSA:1.10.260.40 13 83 2.3E-20 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS03260 3b331d4f274ed725b0e5069aa11cf3fc 201 Gene3D G3DSA:2.60.120.10 121 199 4.8E-24 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS03260 3b331d4f274ed725b0e5069aa11cf3fc 201 Pfam PF13560 Helix-turn-helix domain 21 78 2.8E-16 T 13-09-2016 THL1_RS03260 3b331d4f274ed725b0e5069aa11cf3fc 201 SUPERFAMILY SSF47413 20 83 5.38E-17 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS03260 3b331d4f274ed725b0e5069aa11cf3fc 201 SMART SM00530 24 79 1.5E-14 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS03260 3b331d4f274ed725b0e5069aa11cf3fc 201 PANTHER PTHR10245:SF49 21 201 5.0E-35 T 13-09-2016 THL1_RS01675 8f33280e274d174190c1eff9f2ee4329 251 SMART SM00062 26 250 9.0E-12 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS01675 8f33280e274d174190c1eff9f2ee4329 251 SUPERFAMILY SSF53850 28 246 1.2E-38 T 13-09-2016 THL1_RS01675 8f33280e274d174190c1eff9f2ee4329 251 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 246 2.8E-24 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS01675 8f33280e274d174190c1eff9f2ee4329 251 Gene3D G3DSA:3.40.190.10 27 109 1.6E-16 T 13-09-2016 THL1_RS01675 8f33280e274d174190c1eff9f2ee4329 251 Gene3D G3DSA:3.40.190.10 207 246 1.6E-16 T 13-09-2016 THL1_RS01675 8f33280e274d174190c1eff9f2ee4329 251 PANTHER PTHR35936:SF3 1 248 1.4E-40 T 13-09-2016 THL1_RS01675 8f33280e274d174190c1eff9f2ee4329 251 PANTHER PTHR35936 1 248 1.4E-40 T 13-09-2016 THL1_RS02285 f0ca272e59d6a4507d2a13d833472c6e 360 PIRSF PIRSF019574 3 360 2.5E-112 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02285 f0ca272e59d6a4507d2a13d833472c6e 360 PANTHER PTHR30222 5 358 2.9E-113 T 13-09-2016 THL1_RS02285 f0ca272e59d6a4507d2a13d833472c6e 360 Gene3D G3DSA:3.40.190.10 142 309 5.6E-57 T 13-09-2016 THL1_RS02285 f0ca272e59d6a4507d2a13d833472c6e 360 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 172 191 1.2E-50 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02285 f0ca272e59d6a4507d2a13d833472c6e 360 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 209 228 1.2E-50 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02285 f0ca272e59d6a4507d2a13d833472c6e 360 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 70 84 1.2E-50 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02285 f0ca272e59d6a4507d2a13d833472c6e 360 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 119 135 1.2E-50 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02285 f0ca272e59d6a4507d2a13d833472c6e 360 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 149 163 1.2E-50 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02285 f0ca272e59d6a4507d2a13d833472c6e 360 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 43 64 1.2E-50 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02285 f0ca272e59d6a4507d2a13d833472c6e 360 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 259 278 1.2E-50 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02285 f0ca272e59d6a4507d2a13d833472c6e 360 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 27 43 1.2E-50 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02285 f0ca272e59d6a4507d2a13d833472c6e 360 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 304 330 1.2E-50 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS02285 f0ca272e59d6a4507d2a13d833472c6e 360 Gene3D G3DSA:3.40.190.10 24 141 2.9E-17 T 13-09-2016 THL1_RS02285 f0ca272e59d6a4507d2a13d833472c6e 360 SUPERFAMILY SSF53850 21 357 4.58E-88 T 13-09-2016 THL1_RS02285 f0ca272e59d6a4507d2a13d833472c6e 360 PANTHER PTHR30222:SF11 5 358 2.9E-113 T 13-09-2016 THL1_RS02285 f0ca272e59d6a4507d2a13d833472c6e 360 Pfam PF13416 Bacterial extracellular solute-binding protein 40 325 6.2E-30 T 13-09-2016 THL1_RS01280 399c05ede701cd9d77cc74de77811867 379 SUPERFAMILY SSF53474 15 375 2.29E-98 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS01280 399c05ede701cd9d77cc74de77811867 379 PANTHER PTHR32268 1 377 1.4E-184 T 13-09-2016 THL1_RS01280 399c05ede701cd9d77cc74de77811867 379 PANTHER PTHR32268:SF11 1 377 1.4E-184 T 13-09-2016 THL1_RS01280 399c05ede701cd9d77cc74de77811867 379 PIRSF PIRSF000443 1 379 6.6E-134 T 13-09-2016 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344|UniPathway: UPA00051 THL1_RS01280 399c05ede701cd9d77cc74de77811867 379 Pfam PF00561 alpha/beta hydrolase fold 51 360 8.5E-27 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS01280 399c05ede701cd9d77cc74de77811867 379 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 22 369 1.6E-138 T 13-09-2016 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344|UniPathway: UPA00051 THL1_RS01280 399c05ede701cd9d77cc74de77811867 379 Gene3D G3DSA:3.40.50.1820 241 360 9.6E-34 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS01280 399c05ede701cd9d77cc74de77811867 379 Gene3D G3DSA:3.40.50.1820 34 208 9.6E-34 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS01280 399c05ede701cd9d77cc74de77811867 379 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 8 376 49.805 T 13-09-2016 IPR008220 Homoserine acetyltransferase GO:0004414|GO:0005737|GO:0009086 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344|UniPathway: UPA00051 THL1_RS04985 2b1b6e487966c016ba3e0382f96d5879 241 SUPERFAMILY SSF64438 4 239 3.11E-83 T 13-09-2016 IPR011324 Cytotoxic necrotizing factor-like, catalytic THL1_RS04985 2b1b6e487966c016ba3e0382f96d5879 241 Gene3D G3DSA:3.60.140.10 4 239 2.0E-95 T 13-09-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase THL1_RS04985 2b1b6e487966c016ba3e0382f96d5879 241 PANTHER PTHR30616:SF3 1 241 1.8E-130 T 13-09-2016 THL1_RS04985 2b1b6e487966c016ba3e0382f96d5879 241 PANTHER PTHR30616 1 241 1.8E-130 T 13-09-2016 THL1_RS04985 2b1b6e487966c016ba3e0382f96d5879 241 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 20 238 5.5E-73 T 13-09-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase THL1_RS04985 2b1b6e487966c016ba3e0382f96d5879 241 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 26 239 1.6E-59 T 13-09-2016 IPR003730 Multi-copper polyphenol oxidoreductase, laccase THL1_RS16210 e26b0edea577fafdd0b26432e0a2f7b1 847 Pfam PF10145 Phage-related minor tail protein 243 435 2.2E-43 T 13-09-2016 IPR010090 Phage tail tape measure protein THL1_RS16210 e26b0edea577fafdd0b26432e0a2f7b1 847 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 201 543 1.5E-96 T 13-09-2016 IPR010090 Phage tail tape measure protein THL1_RS02410 dc80c7e175e327d889ac6ef5e103ad12 441 PANTHER PTHR34596 1 441 2.9E-141 T 13-09-2016 THL1_RS02410 dc80c7e175e327d889ac6ef5e103ad12 441 Pfam PF03573 outer membrane porin, OprD family 32 440 1.7E-130 T 13-09-2016 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 THL1_RS02410 dc80c7e175e327d889ac6ef5e103ad12 441 Gene3D G3DSA:2.40.160.10 34 441 3.6E-130 T 13-09-2016 IPR023614 Porin domain THL1_RS11825 8835954f908574d1805f5b66750589dd 166 Pfam PF00582 Universal stress protein family 1 156 6.1E-23 T 13-09-2016 IPR006016 UspA GO:0006950 THL1_RS11825 8835954f908574d1805f5b66750589dd 166 PRINTS PR01438 Universal stress protein signature 2 20 3.6E-5 T 13-09-2016 IPR006015 Universal stress protein A THL1_RS11825 8835954f908574d1805f5b66750589dd 166 PRINTS PR01438 Universal stress protein signature 116 128 3.6E-5 T 13-09-2016 IPR006015 Universal stress protein A THL1_RS11825 8835954f908574d1805f5b66750589dd 166 PRINTS PR01438 Universal stress protein signature 134 156 3.6E-5 T 13-09-2016 IPR006015 Universal stress protein A THL1_RS11825 8835954f908574d1805f5b66750589dd 166 SUPERFAMILY SSF52402 1 156 6.36E-25 T 13-09-2016 THL1_RS11825 8835954f908574d1805f5b66750589dd 166 Gene3D G3DSA:3.40.50.620 1 156 6.3E-27 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS11825 8835954f908574d1805f5b66750589dd 166 PANTHER PTHR31964:SF42 1 156 2.6E-30 T 13-09-2016 THL1_RS11825 8835954f908574d1805f5b66750589dd 166 PANTHER PTHR31964 1 156 2.6E-30 T 13-09-2016 THL1_RS13200 35f31612fd124028c7ce616d38939df2 647 Pfam PF00501 AMP-binding enzyme 31 481 5.6E-71 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS13200 35f31612fd124028c7ce616d38939df2 647 Gene3D G3DSA:3.30.300.30 476 575 2.2E-25 T 13-09-2016 THL1_RS13200 35f31612fd124028c7ce616d38939df2 647 SUPERFAMILY SSF56801 24 578 1.31E-114 T 13-09-2016 THL1_RS13200 35f31612fd124028c7ce616d38939df2 647 Gene3D G3DSA:2.30.38.10 399 475 5.3E-13 T 13-09-2016 THL1_RS13200 35f31612fd124028c7ce616d38939df2 647 Gene3D G3DSA:3.40.50.980 230 392 2.8E-31 T 13-09-2016 THL1_RS13200 35f31612fd124028c7ce616d38939df2 647 PANTHER PTHR24096:SF170 192 619 2.1E-193 T 13-09-2016 THL1_RS13200 35f31612fd124028c7ce616d38939df2 647 Pfam PF13193 AMP-binding enzyme C-terminal domain 491 566 8.4E-15 T 13-09-2016 IPR025110 AMP-binding enzyme C-terminal domain THL1_RS13200 35f31612fd124028c7ce616d38939df2 647 Gene3D G3DSA:3.40.50.980 26 229 4.3E-20 T 13-09-2016 THL1_RS13200 35f31612fd124028c7ce616d38939df2 647 PANTHER PTHR24096:SF170 6 166 2.1E-193 T 13-09-2016 THL1_RS13200 35f31612fd124028c7ce616d38939df2 647 PANTHER PTHR24096 6 166 2.1E-193 T 13-09-2016 THL1_RS13200 35f31612fd124028c7ce616d38939df2 647 PANTHER PTHR24096 192 619 2.1E-193 T 13-09-2016 THL1_RS02445 51ac74956b0a36d1ea3d1db17bc4c098 190 Hamap MF_00825 3-hydroxyanthranilate 3,4-dioxygenase [nbaC]. 6 175 30.937 T 13-09-2016 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|UniPathway: UPA00253 THL1_RS02445 51ac74956b0a36d1ea3d1db17bc4c098 190 PANTHER PTHR15497 6 173 2.5E-50 T 13-09-2016 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|UniPathway: UPA00253 THL1_RS02445 51ac74956b0a36d1ea3d1db17bc4c098 190 TIGRFAM TIGR03037 anthran_nbaC: 3-hydroxyanthranilate 3,4-dioxygenase 10 170 5.3E-75 T 13-09-2016 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|UniPathway: UPA00253 THL1_RS02445 51ac74956b0a36d1ea3d1db17bc4c098 190 Pfam PF06052 3-hydroxyanthranilic acid dioxygenase 8 156 7.4E-42 T 13-09-2016 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|UniPathway: UPA00253 THL1_RS02445 51ac74956b0a36d1ea3d1db17bc4c098 190 SUPERFAMILY SSF51182 7 175 7.69E-48 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS02445 51ac74956b0a36d1ea3d1db17bc4c098 190 Gene3D G3DSA:2.60.120.10 9 118 2.0E-14 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS09520 95ed681e748121359102c6bc82b5c3eb 798 SUPERFAMILY SSF56003 147 779 1.19E-204 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS09520 95ed681e748121359102c6bc82b5c3eb 798 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 167 709 1.5E-205 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS09520 95ed681e748121359102c6bc82b5c3eb 798 SUPERFAMILY SSF54665 21 147 3.27E-38 T 13-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead THL1_RS09520 95ed681e748121359102c6bc82b5c3eb 798 Gene3D G3DSA:3.30.365.10 194 288 1.5E-31 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS09520 95ed681e748121359102c6bc82b5c3eb 798 Gene3D G3DSA:3.30.365.10 624 779 7.8E-88 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS09520 95ed681e748121359102c6bc82b5c3eb 798 Gene3D G3DSA:3.30.365.10 366 457 7.8E-88 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS09520 95ed681e748121359102c6bc82b5c3eb 798 SMART SM01008 39 146 4.6E-38 T 13-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead THL1_RS09520 95ed681e748121359102c6bc82b5c3eb 798 Gene3D G3DSA:3.90.1170.50 25 146 1.6E-37 T 13-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead THL1_RS09520 95ed681e748121359102c6bc82b5c3eb 798 PANTHER PTHR11908:SF66 12 782 0.0 T 13-09-2016 THL1_RS09520 95ed681e748121359102c6bc82b5c3eb 798 Gene3D G3DSA:3.30.365.10 458 613 1.2E-53 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS09520 95ed681e748121359102c6bc82b5c3eb 798 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 39 145 2.6E-22 T 13-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead THL1_RS09520 95ed681e748121359102c6bc82b5c3eb 798 TIGRFAM TIGR02965 xanthine_xdhB: xanthine dehydrogenase, molybdopterin binding subunit 25 781 0.0 T 13-09-2016 IPR014309 Xanthine dehydrogenase, molybdopterin binding subunit GO:0030151 KEGG: 00230+1.17.1.4+1.17.3.2|KEGG: 00232+1.17.3.2|KEGG: 00983+1.17.3.2|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 THL1_RS09520 95ed681e748121359102c6bc82b5c3eb 798 PANTHER PTHR11908 12 782 0.0 T 13-09-2016 THL1_RS09520 95ed681e748121359102c6bc82b5c3eb 798 Gene3D G3DSA:3.30.365.10 290 365 5.8E-24 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS09520 95ed681e748121359102c6bc82b5c3eb 798 Gene3D G3DSA:3.30.365.10 147 193 5.8E-24 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS14315 f1f7b987a75d027d34b2fc30aea77adf 170 Pfam PF07681 DoxX 33 133 3.3E-18 T 13-09-2016 IPR032808 DoxX family THL1_RS06490 4db14fe3dc5711daf3829b9c7e72968f 271 SUPERFAMILY SSF51735 5 243 6.12E-57 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS06490 4db14fe3dc5711daf3829b9c7e72968f 271 PANTHER PTHR24322 11 140 1.4E-41 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06490 4db14fe3dc5711daf3829b9c7e72968f 271 PANTHER PTHR24322 156 189 1.4E-41 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06490 4db14fe3dc5711daf3829b9c7e72968f 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.6E-8 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06490 4db14fe3dc5711daf3829b9c7e72968f 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.6E-8 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06490 4db14fe3dc5711daf3829b9c7e72968f 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.6E-8 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06490 4db14fe3dc5711daf3829b9c7e72968f 271 Pfam PF00106 short chain dehydrogenase 7 200 2.0E-45 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06490 4db14fe3dc5711daf3829b9c7e72968f 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS06490 4db14fe3dc5711daf3829b9c7e72968f 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 194 0.0083 T 13-09-2016 THL1_RS06490 4db14fe3dc5711daf3829b9c7e72968f 271 Gene3D G3DSA:3.40.50.720 6 238 8.1E-57 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS06490 4db14fe3dc5711daf3829b9c7e72968f 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.9E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06490 4db14fe3dc5711daf3829b9c7e72968f 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.9E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06490 4db14fe3dc5711daf3829b9c7e72968f 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.9E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06490 4db14fe3dc5711daf3829b9c7e72968f 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.9E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06490 4db14fe3dc5711daf3829b9c7e72968f 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.9E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07365 fe381d5441fbf10d657b5bd549b3c063 155 PANTHER PTHR36180:SF2 1 104 1.6E-13 T 13-09-2016 THL1_RS07365 fe381d5441fbf10d657b5bd549b3c063 155 Pfam PF02498 BRO family, N-terminal domain 18 101 7.6E-10 T 13-09-2016 IPR003497 BRO N-terminal domain THL1_RS07365 fe381d5441fbf10d657b5bd549b3c063 155 SMART SM01040 16 102 8.7E-8 T 13-09-2016 IPR003497 BRO N-terminal domain THL1_RS07365 fe381d5441fbf10d657b5bd549b3c063 155 PANTHER PTHR36180 1 104 1.6E-13 T 13-09-2016 THL1_RS19680 df3c6c98b91f2f2b4cb8954fb8408443 366 PANTHER PTHR30381 1 366 1.6E-222 T 13-09-2016 THL1_RS19680 df3c6c98b91f2f2b4cb8954fb8408443 366 PANTHER PTHR30381:SF1 1 366 1.6E-222 T 13-09-2016 THL1_RS19680 df3c6c98b91f2f2b4cb8954fb8408443 366 Hamap MF_00416 Flagellar P-ring protein [flgI]. 3 366 41.04 T 13-09-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THL1_RS19680 df3c6c98b91f2f2b4cb8954fb8408443 366 Pfam PF02119 Flagellar P-ring protein 21 365 2.6E-143 T 13-09-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THL1_RS19680 df3c6c98b91f2f2b4cb8954fb8408443 366 PRINTS PR01010 Flagellar P-ring protein signature 36 51 1.8E-87 T 13-09-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THL1_RS19680 df3c6c98b91f2f2b4cb8954fb8408443 366 PRINTS PR01010 Flagellar P-ring protein signature 56 71 1.8E-87 T 13-09-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THL1_RS19680 df3c6c98b91f2f2b4cb8954fb8408443 366 PRINTS PR01010 Flagellar P-ring protein signature 163 181 1.8E-87 T 13-09-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THL1_RS19680 df3c6c98b91f2f2b4cb8954fb8408443 366 PRINTS PR01010 Flagellar P-ring protein signature 189 207 1.8E-87 T 13-09-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THL1_RS19680 df3c6c98b91f2f2b4cb8954fb8408443 366 PRINTS PR01010 Flagellar P-ring protein signature 253 265 1.8E-87 T 13-09-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THL1_RS19680 df3c6c98b91f2f2b4cb8954fb8408443 366 PRINTS PR01010 Flagellar P-ring protein signature 21 36 1.8E-87 T 13-09-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THL1_RS19680 df3c6c98b91f2f2b4cb8954fb8408443 366 PRINTS PR01010 Flagellar P-ring protein signature 122 140 1.8E-87 T 13-09-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THL1_RS19680 df3c6c98b91f2f2b4cb8954fb8408443 366 PRINTS PR01010 Flagellar P-ring protein signature 105 122 1.8E-87 T 13-09-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THL1_RS19680 df3c6c98b91f2f2b4cb8954fb8408443 366 PRINTS PR01010 Flagellar P-ring protein signature 83 102 1.8E-87 T 13-09-2016 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 THL1_RS03935 4bc90a51b0fbd0098d82b6f75ef10fda 252 PANTHER PTHR30269 1 250 1.2E-74 T 13-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 THL1_RS03935 4bc90a51b0fbd0098d82b6f75ef10fda 252 PANTHER PTHR30269:SF10 1 250 1.2E-74 T 13-09-2016 THL1_RS03935 4bc90a51b0fbd0098d82b6f75ef10fda 252 Pfam PF01925 Sulfite exporter TauE/SafE 9 247 1.3E-33 T 13-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 THL1_RS23575 935b1ce11eaa86e53441ab75ac49a514 260 SUPERFAMILY SSF53639 20 222 5.3E-56 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS23575 935b1ce11eaa86e53441ab75ac49a514 260 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 26 204 9.5E-41 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS23575 935b1ce11eaa86e53441ab75ac49a514 260 SMART SM01007 25 204 2.8E-54 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS23575 935b1ce11eaa86e53441ab75ac49a514 260 PANTHER PTHR10672 17 258 3.1E-105 T 13-09-2016 THL1_RS23575 935b1ce11eaa86e53441ab75ac49a514 260 Gene3D G3DSA:3.40.225.10 20 228 4.6E-57 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS26280 a703aa76fb9e6e56baa2a7e2e8224753 1481 PANTHER PTHR11938 4 1478 0.0 T 13-09-2016 THL1_RS26280 a703aa76fb9e6e56baa2a7e2e8224753 1481 Gene3D G3DSA:3.60.20.10 15 437 1.3E-162 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS26280 a703aa76fb9e6e56baa2a7e2e8224753 1481 Pfam PF04898 Glutamate synthase central domain 457 736 6.5E-103 T 13-09-2016 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 UniPathway: UPA00045 THL1_RS26280 a703aa76fb9e6e56baa2a7e2e8224753 1481 Gene3D G3DSA:3.20.20.70 808 1186 2.9E-164 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS26280 a703aa76fb9e6e56baa2a7e2e8224753 1481 SUPERFAMILY SSF51395 446 1187 5.29E-253 T 13-09-2016 THL1_RS26280 a703aa76fb9e6e56baa2a7e2e8224753 1481 Gene3D G3DSA:2.160.20.60 1212 1466 1.0E-96 T 13-09-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 THL1_RS26280 a703aa76fb9e6e56baa2a7e2e8224753 1481 SUPERFAMILY SSF69336 1212 1466 3.79E-90 T 13-09-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 THL1_RS26280 a703aa76fb9e6e56baa2a7e2e8224753 1481 SUPERFAMILY SSF56235 15 431 1.03E-141 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS26280 a703aa76fb9e6e56baa2a7e2e8224753 1481 Pfam PF00310 Glutamine amidotransferases class-II 15 428 1.4E-171 T 13-09-2016 IPR017932 Glutamine amidotransferase type 2 domain THL1_RS26280 a703aa76fb9e6e56baa2a7e2e8224753 1481 Pfam PF01645 Conserved region in glutamate synthase 792 1155 3.3E-150 T 13-09-2016 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 THL1_RS26280 a703aa76fb9e6e56baa2a7e2e8224753 1481 PANTHER PTHR11938:SF1 4 1478 0.0 T 13-09-2016 THL1_RS26280 a703aa76fb9e6e56baa2a7e2e8224753 1481 Gene3D G3DSA:3.20.20.70 439 778 1.1E-94 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS26280 a703aa76fb9e6e56baa2a7e2e8224753 1481 Pfam PF01493 GXGXG motif 1236 1422 1.6E-79 T 13-09-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 THL1_RS24335 c60d0cce6a300c08440616344f8c7947 339 Gene3D G3DSA:3.40.50.150 45 338 1.3E-53 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS24335 c60d0cce6a300c08440616344f8c7947 339 SUPERFAMILY SSF53335 16 324 6.99E-46 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS24335 c60d0cce6a300c08440616344f8c7947 339 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 32 302 2.1E-27 T 13-09-2016 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 THL1_RS24335 c60d0cce6a300c08440616344f8c7947 339 PANTHER PTHR11061 18 311 3.1E-74 T 13-09-2016 THL1_RS24335 c60d0cce6a300c08440616344f8c7947 339 PANTHER PTHR11061:SF34 18 311 3.1E-74 T 13-09-2016 THL1_RS27695 58406141f2bdfee83226b04d3c3d7788 193 PANTHER PTHR33420:SF8 1 193 5.5E-47 T 13-09-2016 THL1_RS27695 58406141f2bdfee83226b04d3c3d7788 193 SUPERFAMILY SSF49401 23 193 2.24E-20 T 13-09-2016 IPR008966 Adhesion domain THL1_RS27695 58406141f2bdfee83226b04d3c3d7788 193 Gene3D G3DSA:2.60.40.1090 22 193 6.7E-21 T 13-09-2016 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 THL1_RS27695 58406141f2bdfee83226b04d3c3d7788 193 Pfam PF00419 Fimbrial protein 24 193 4.5E-15 T 13-09-2016 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 THL1_RS27695 58406141f2bdfee83226b04d3c3d7788 193 PANTHER PTHR33420 1 193 5.5E-47 T 13-09-2016 THL1_RS06835 6c4da6759fe54d91422e51e76fb93563 552 PANTHER PTHR11819 34 541 3.1E-291 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS06835 6c4da6759fe54d91422e51e76fb93563 552 PANTHER PTHR11819:SF13 34 541 3.1E-291 T 13-09-2016 THL1_RS06835 6c4da6759fe54d91422e51e76fb93563 552 Pfam PF00474 Sodium:solute symporter family 65 471 1.7E-126 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS06835 6c4da6759fe54d91422e51e76fb93563 552 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 65 469 5.1E-61 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS06835 6c4da6759fe54d91422e51e76fb93563 552 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 180 205 - T 13-09-2016 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 THL1_RS06835 6c4da6759fe54d91422e51e76fb93563 552 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 453 473 - T 13-09-2016 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 THL1_RS04640 08815423120ea866b008f2b74144e369 406 SUPERFAMILY SSF46626 173 279 6.94E-13 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS04640 08815423120ea866b008f2b74144e369 406 SUPERFAMILY SSF46626 297 400 1.4E-18 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS04640 08815423120ea866b008f2b74144e369 406 PANTHER PTHR35008:SF5 10 405 3.2E-175 T 13-09-2016 THL1_RS04640 08815423120ea866b008f2b74144e369 406 Pfam PF00034 Cytochrome c 28 127 1.2E-8 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS04640 08815423120ea866b008f2b74144e369 406 Pfam PF00034 Cytochrome c 296 384 2.4E-9 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS04640 08815423120ea866b008f2b74144e369 406 Gene3D G3DSA:1.10.760.10 297 404 3.6E-18 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS04640 08815423120ea866b008f2b74144e369 406 PIRSF PIRSF000018 1 406 6.2E-141 T 13-09-2016 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 THL1_RS04640 08815423120ea866b008f2b74144e369 406 SUPERFAMILY SSF46626 13 149 2.75E-23 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS04640 08815423120ea866b008f2b74144e369 406 Gene3D G3DSA:1.10.760.10 170 274 8.9E-6 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS04640 08815423120ea866b008f2b74144e369 406 Gene3D G3DSA:1.10.760.10 23 127 1.7E-19 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS04640 08815423120ea866b008f2b74144e369 406 PANTHER PTHR35008 10 405 3.2E-175 T 13-09-2016 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 8 638 3.5E-298 T 13-09-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 PANTHER PTHR10169 3 418 0.0 T 13-09-2016 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 PANTHER PTHR10169:SF48 451 642 0.0 T 13-09-2016 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 SUPERFAMILY SSF56719 30 523 3.53E-184 T 13-09-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 SMART SM00434 11 500 0.0 T 13-09-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 SUPERFAMILY SSF101904 683 895 1.28E-99 T 13-09-2016 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 SUPERFAMILY SSF101904 534 639 1.28E-99 T 13-09-2016 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 PANTHER PTHR10169:SF48 686 853 0.0 T 13-09-2016 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 Gene3D G3DSA:3.90.199.10 34 216 2.6E-85 T 13-09-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 Gene3D G3DSA:2.120.10.90 689 883 1.2E-130 T 13-09-2016 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 Gene3D G3DSA:2.120.10.90 533 657 1.2E-130 T 13-09-2016 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 PANTHER PTHR10169 686 853 0.0 T 13-09-2016 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 507 1.8E-152 T 13-09-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 887 29.657 T 13-09-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 PANTHER PTHR10169 451 642 0.0 T 13-09-2016 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 541 586 4.9E-8 T 13-09-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 591 638 1.3E-8 T 13-09-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 837 883 4.8E-13 T 13-09-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 689 732 4.2E-8 T 13-09-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 788 833 1.9E-13 T 13-09-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 737 781 6.2E-15 T 13-09-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 Gene3D G3DSA:1.10.268.10 364 498 6.3E-48 T 13-09-2016 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 PANTHER PTHR10169:SF48 3 418 0.0 T 13-09-2016 THL1_RS19200 4e804471fd8061bac3e552fc28e50602 925 Gene3D G3DSA:3.30.1360.40 236 334 1.8E-38 T 13-09-2016 IPR024946 Arginine repressor C-terminal-like domain THL1_RS05200 eba739ca4a2ae0e2500b599ec2dcb425 301 SUPERFAMILY SSF50891 176 286 4.17E-8 T 13-09-2016 IPR029000 Cyclophilin-like domain THL1_RS05200 eba739ca4a2ae0e2500b599ec2dcb425 301 PANTHER PTHR18866:SF102 147 258 1.4E-30 T 13-09-2016 THL1_RS05200 eba739ca4a2ae0e2500b599ec2dcb425 301 PANTHER PTHR18866 147 258 1.4E-30 T 13-09-2016 THL1_RS05200 eba739ca4a2ae0e2500b599ec2dcb425 301 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 1 292 2.3E-70 T 13-09-2016 IPR003778 Carboxyltransferase domain, subdomain A and B THL1_RS05200 eba739ca4a2ae0e2500b599ec2dcb425 301 SMART SM00797 20 296 3.3E-113 T 13-09-2016 IPR003778 Carboxyltransferase domain, subdomain A and B THL1_RS05200 eba739ca4a2ae0e2500b599ec2dcb425 301 Pfam PF02626 Allophanate hydrolase subunit 2 21 281 2.2E-77 T 13-09-2016 IPR003778 Carboxyltransferase domain, subdomain A and B THL1_RS24810 c52c50e1b42441628f778bb59812dd36 209 PANTHER PTHR12151 56 155 9.0E-21 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS24810 c52c50e1b42441628f778bb59812dd36 209 Pfam PF02630 SCO1/SenC 56 146 3.2E-15 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS24810 c52c50e1b42441628f778bb59812dd36 209 Gene3D G3DSA:3.40.30.10 54 166 1.3E-27 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS24810 c52c50e1b42441628f778bb59812dd36 209 SUPERFAMILY SSF52833 49 200 2.5E-27 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS00635 aa1f81158d03c865ea9f4e722bac9afc 196 PIRSF PIRSF006386 1 196 9.8E-70 T 13-09-2016 IPR014440 HCCA isomerase/glutathione S-transferase kappa THL1_RS00635 aa1f81158d03c865ea9f4e722bac9afc 196 PANTHER PTHR13887:SF22 1 195 2.1E-77 T 13-09-2016 THL1_RS00635 aa1f81158d03c865ea9f4e722bac9afc 196 SUPERFAMILY SSF52833 1 195 4.48E-49 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS00635 aa1f81158d03c865ea9f4e722bac9afc 196 Gene3D G3DSA:3.40.30.10 3 195 6.6E-65 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS00635 aa1f81158d03c865ea9f4e722bac9afc 196 Pfam PF01323 DSBA-like thioredoxin domain 4 196 1.5E-44 T 13-09-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 THL1_RS00635 aa1f81158d03c865ea9f4e722bac9afc 196 PANTHER PTHR13887 1 195 2.1E-77 T 13-09-2016 THL1_RS25700 f2cadfce9a0bcc1ad1e77a55295a0b47 427 SUPERFAMILY SSF51905 28 252 1.81E-38 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS25700 f2cadfce9a0bcc1ad1e77a55295a0b47 427 SUPERFAMILY SSF51905 344 399 1.81E-38 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS25700 f2cadfce9a0bcc1ad1e77a55295a0b47 427 Pfam PF01266 FAD dependent oxidoreductase 29 380 9.7E-49 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS25700 f2cadfce9a0bcc1ad1e77a55295a0b47 427 Gene3D G3DSA:3.50.50.60 171 251 7.4E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS25700 f2cadfce9a0bcc1ad1e77a55295a0b47 427 Gene3D G3DSA:3.50.50.60 344 398 7.4E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS25700 f2cadfce9a0bcc1ad1e77a55295a0b47 427 Gene3D G3DSA:3.50.50.60 20 118 7.4E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS25700 f2cadfce9a0bcc1ad1e77a55295a0b47 427 PANTHER PTHR13847 7 394 4.7E-174 T 13-09-2016 THL1_RS25700 f2cadfce9a0bcc1ad1e77a55295a0b47 427 PANTHER PTHR13847:SF190 7 394 4.7E-174 T 13-09-2016 THL1_RS05915 08398054393811fa98d9be4f14ba4121 257 PANTHER PTHR12029 3 182 3.7E-41 T 13-09-2016 THL1_RS05915 08398054393811fa98d9be4f14ba4121 257 Gene3D G3DSA:3.40.1280.10 3 161 1.9E-34 T 13-09-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THL1_RS05915 08398054393811fa98d9be4f14ba4121 257 Pfam PF00588 SpoU rRNA Methylase family 5 155 7.3E-35 T 13-09-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 THL1_RS05915 08398054393811fa98d9be4f14ba4121 257 SUPERFAMILY SSF75217 4 168 5.56E-39 T 13-09-2016 IPR029028 Alpha/beta knot methyltransferases THL1_RS05915 08398054393811fa98d9be4f14ba4121 257 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 246 1.5E-75 T 13-09-2016 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 THL1_RS05915 08398054393811fa98d9be4f14ba4121 257 PIRSF PIRSF004808 1 251 5.8E-73 T 13-09-2016 IPR004384 RNA methyltransferase TrmH, group 1 GO:0006396|GO:0008173 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 THL1_RS20515 56cf78924c052c75daaa8811aafcd5de 288 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 231 3.3E-27 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS20515 56cf78924c052c75daaa8811aafcd5de 288 PANTHER PTHR11941 1 229 7.4E-44 T 13-09-2016 THL1_RS20515 56cf78924c052c75daaa8811aafcd5de 288 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 113 133 - T 13-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THL1_RS20515 56cf78924c052c75daaa8811aafcd5de 288 SUPERFAMILY SSF52096 6 256 1.38E-51 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20515 56cf78924c052c75daaa8811aafcd5de 288 Gene3D G3DSA:3.90.226.10 5 233 1.7E-49 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS03840 08af4e39cb205b4d21b5faa7babc1a3b 154 PANTHER PTHR30455 2 150 3.2E-72 T 13-09-2016 THL1_RS03840 08af4e39cb205b4d21b5faa7babc1a3b 154 PANTHER PTHR30455:SF2 2 150 3.2E-72 T 13-09-2016 THL1_RS03840 08af4e39cb205b4d21b5faa7babc1a3b 154 Pfam PF03477 ATP cone domain 52 136 6.6E-14 T 13-09-2016 IPR005144 ATP-cone domain THL1_RS03840 08af4e39cb205b4d21b5faa7babc1a3b 154 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 6.9E-72 T 13-09-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 THL1_RS03840 08af4e39cb205b4d21b5faa7babc1a3b 154 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 89.735 T 13-09-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 SUPERFAMILY SSF52374 3 199 7.93E-129 T 13-09-2016 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 SUPERFAMILY SSF52374 401 653 7.93E-129 T 13-09-2016 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 399 414 2.5E-32 T 13-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 51 62 2.5E-32 T 13-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 568 577 2.5E-32 T 13-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 235 258 2.5E-32 T 13-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 529 542 2.5E-32 T 13-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 PANTHER PTHR11946 898 941 0.0 T 13-09-2016 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 PANTHER PTHR11946 6 212 0.0 T 13-09-2016 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 PANTHER PTHR11946 231 256 0.0 T 13-09-2016 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 PANTHER PTHR11946 279 882 0.0 T 13-09-2016 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 SUPERFAMILY SSF47323 659 935 3.36E-79 T 13-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 Gene3D G3DSA:1.10.730.10 649 796 1.9E-43 T 13-09-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 2 935 21.23 T 13-09-2016 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 28 648 2.3E-229 T 13-09-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 Pfam PF08264 Anticodon-binding domain of tRNA 692 848 2.5E-29 T 13-09-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 PANTHER PTHR11946:SF11 6 212 0.0 T 13-09-2016 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 PANTHER PTHR11946:SF11 231 256 0.0 T 13-09-2016 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 PANTHER PTHR11946:SF11 279 882 0.0 T 13-09-2016 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 Gene3D G3DSA:3.40.50.620 13 197 6.9E-130 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS04860 f96fc73458be868db033b68da46156d6 944 Gene3D G3DSA:3.40.50.620 404 643 6.9E-130 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS04860 f96fc73458be868db033b68da46156d6 944 Gene3D G3DSA:3.90.740.10 203 387 2.3E-54 T 13-09-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 15 850 3.6E-275 T 13-09-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 SUPERFAMILY SSF50677 201 401 5.44E-54 T 13-09-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 58 69 - T 13-09-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 PANTHER PTHR11946:SF11 898 941 0.0 T 13-09-2016 THL1_RS04860 f96fc73458be868db033b68da46156d6 944 Pfam PF06827 Zinc finger found in FPG and IleRS 906 932 1.5E-4 T 13-09-2016 IPR010663 Zinc finger, FPG/IleRS-type THL1_RS14205 c634451290c464aad026efbd4e419024 210 SMART SM00421 142 199 1.3E-18 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS14205 c634451290c464aad026efbd4e419024 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 6.4E-9 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS14205 c634451290c464aad026efbd4e419024 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 6.4E-9 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS14205 c634451290c464aad026efbd4e419024 210 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 6.4E-9 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS14205 c634451290c464aad026efbd4e419024 210 Gene3D G3DSA:1.10.10.10 119 206 1.1E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14205 c634451290c464aad026efbd4e419024 210 SMART SM00448 1 114 6.9E-34 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS14205 c634451290c464aad026efbd4e419024 210 SUPERFAMILY SSF46894 128 205 2.69E-18 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS14205 c634451290c464aad026efbd4e419024 210 PANTHER PTHR26402:SF210 1 207 2.6E-57 T 13-09-2016 THL1_RS14205 c634451290c464aad026efbd4e419024 210 Gene3D G3DSA:3.40.50.2300 1 118 7.4E-35 T 13-09-2016 THL1_RS14205 c634451290c464aad026efbd4e419024 210 SUPERFAMILY SSF52172 1 129 6.97E-35 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS14205 c634451290c464aad026efbd4e419024 210 PANTHER PTHR26402 1 207 2.6E-57 T 13-09-2016 THL1_RS14205 c634451290c464aad026efbd4e419024 210 Pfam PF00072 Response regulator receiver domain 3 115 1.0E-26 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS14205 c634451290c464aad026efbd4e419024 210 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 199 1.1E-14 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS14080 823b09d420e3c3b3c8eb32e884ba36e6 530 SUPERFAMILY SSF49503 394 528 2.16E-27 T 13-09-2016 IPR008972 Cupredoxin THL1_RS14080 823b09d420e3c3b3c8eb32e884ba36e6 530 Gene3D G3DSA:2.60.40.420 413 529 1.3E-29 T 13-09-2016 IPR008972 Cupredoxin THL1_RS14080 823b09d420e3c3b3c8eb32e884ba36e6 530 PANTHER PTHR11709:SF2 177 529 4.3E-62 T 13-09-2016 THL1_RS14080 823b09d420e3c3b3c8eb32e884ba36e6 530 PANTHER PTHR11709 177 529 4.3E-62 T 13-09-2016 THL1_RS14080 823b09d420e3c3b3c8eb32e884ba36e6 530 SUPERFAMILY SSF49503 223 347 2.08E-17 T 13-09-2016 IPR008972 Cupredoxin THL1_RS14080 823b09d420e3c3b3c8eb32e884ba36e6 530 ProSitePatterns PS00080 Multicopper oxidases signature 2. 512 523 - T 13-09-2016 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 THL1_RS14080 823b09d420e3c3b3c8eb32e884ba36e6 530 SUPERFAMILY SSF49503 39 205 1.75E-8 T 13-09-2016 IPR008972 Cupredoxin THL1_RS14080 823b09d420e3c3b3c8eb32e884ba36e6 530 Pfam PF07731 Multicopper oxidase 414 529 4.4E-20 T 13-09-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 THL1_RS14080 823b09d420e3c3b3c8eb32e884ba36e6 530 Gene3D G3DSA:2.60.40.420 43 201 4.1E-11 T 13-09-2016 IPR008972 Cupredoxin THL1_RS14080 823b09d420e3c3b3c8eb32e884ba36e6 530 Gene3D G3DSA:2.60.40.420 219 341 1.9E-24 T 13-09-2016 IPR008972 Cupredoxin THL1_RS24065 c32b2e7f4d0ee4cf532f4050ae898fa0 303 PANTHER PTHR12715 16 299 3.8E-59 T 13-09-2016 THL1_RS24065 c32b2e7f4d0ee4cf532f4050ae898fa0 303 SUPERFAMILY SSF103481 45 149 3.79E-10 T 13-09-2016 THL1_RS24065 c32b2e7f4d0ee4cf532f4050ae898fa0 303 PANTHER PTHR12715:SF12 16 299 3.8E-59 T 13-09-2016 THL1_RS24065 c32b2e7f4d0ee4cf532f4050ae898fa0 303 Pfam PF00892 EamA-like transporter family 160 297 3.1E-22 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS24065 c32b2e7f4d0ee4cf532f4050ae898fa0 303 Pfam PF00892 EamA-like transporter family 12 145 1.3E-17 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS24065 c32b2e7f4d0ee4cf532f4050ae898fa0 303 SUPERFAMILY SSF103481 199 301 2.62E-13 T 13-09-2016 THL1_RS27265 1ab73d1d42a660482cb8204b6b5ad900 105 Pfam PF05164 Cell division protein ZapA 8 91 3.0E-24 T 13-09-2016 IPR007838 Cell division protein ZapA-like THL1_RS27265 1ab73d1d42a660482cb8204b6b5ad900 105 PANTHER PTHR34981 4 99 5.0E-27 T 13-09-2016 THL1_RS27265 1ab73d1d42a660482cb8204b6b5ad900 105 SUPERFAMILY SSF102829 7 95 7.45E-25 T 13-09-2016 IPR007838 Cell division protein ZapA-like THL1_RS27265 1ab73d1d42a660482cb8204b6b5ad900 105 PANTHER PTHR34981:SF1 4 99 5.0E-27 T 13-09-2016 THL1_RS21580 4e0bc56628302714349318ce92cb9411 224 PANTHER PTHR30231 15 222 1.0E-116 T 13-09-2016 THL1_RS21580 4e0bc56628302714349318ce92cb9411 224 Hamap MF_00157 Ribonuclease T [rnt]. 1 224 112.156 T 13-09-2016 IPR005987 Ribonuclease T GO:0004540|GO:0006396 THL1_RS21580 4e0bc56628302714349318ce92cb9411 224 Gene3D G3DSA:3.30.420.10 22 220 9.0E-58 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS21580 4e0bc56628302714349318ce92cb9411 224 TIGRFAM TIGR01298 RNaseT: ribonuclease T 22 220 2.6E-113 T 13-09-2016 IPR005987 Ribonuclease T GO:0004540|GO:0006396 THL1_RS21580 4e0bc56628302714349318ce92cb9411 224 Pfam PF00929 Exonuclease 32 206 3.2E-34 T 13-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III THL1_RS21580 4e0bc56628302714349318ce92cb9411 224 SMART SM00479 30 215 3.0E-25 T 13-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III THL1_RS21580 4e0bc56628302714349318ce92cb9411 224 PANTHER PTHR30231:SF2 15 222 1.0E-116 T 13-09-2016 THL1_RS21580 4e0bc56628302714349318ce92cb9411 224 SUPERFAMILY SSF53098 21 219 2.01E-56 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS04965 ff19fdf8e39e3740a43e4ee60457e285 543 SUPERFAMILY SSF52402 262 525 2.87E-77 T 13-09-2016 THL1_RS04965 ff19fdf8e39e3740a43e4ee60457e285 543 Gene3D G3DSA:3.60.110.10 4 247 7.6E-66 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS04965 ff19fdf8e39e3740a43e4ee60457e285 543 PANTHER PTHR23090 2 537 4.1E-163 T 13-09-2016 THL1_RS04965 ff19fdf8e39e3740a43e4ee60457e285 543 TIGRFAM TIGR00552 nadE: NAD+ synthetase 275 515 3.4E-59 T 13-09-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 THL1_RS04965 ff19fdf8e39e3740a43e4ee60457e285 543 SUPERFAMILY SSF56317 4 247 3.14E-65 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS04965 ff19fdf8e39e3740a43e4ee60457e285 543 Pfam PF00795 Carbon-nitrogen hydrolase 9 247 3.8E-29 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS04965 ff19fdf8e39e3740a43e4ee60457e285 543 Gene3D G3DSA:3.40.50.620 264 523 1.9E-75 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS04965 ff19fdf8e39e3740a43e4ee60457e285 543 Pfam PF02540 NAD synthase 268 516 3.5E-73 T 13-09-2016 IPR022310 NAD/GMP synthase THL1_RS21280 7a873512e7c27cdb9b47213ed7bac33d 248 PANTHER PTHR30456 5 248 1.1E-142 T 13-09-2016 THL1_RS21280 7a873512e7c27cdb9b47213ed7bac33d 248 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 9 242 1.6E-97 T 13-09-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 THL1_RS21280 7a873512e7c27cdb9b47213ed7bac33d 248 SUPERFAMILY SSF63892 7 242 1.06E-97 T 13-09-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 THL1_RS21280 7a873512e7c27cdb9b47213ed7bac33d 248 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 246 125.669 T 13-09-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 THL1_RS21280 7a873512e7c27cdb9b47213ed7bac33d 248 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 9 241 1.0E-101 T 13-09-2016 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2|UniPathway: UPA00244 THL1_RS21280 7a873512e7c27cdb9b47213ed7bac33d 248 Gene3D G3DSA:3.20.20.70 6 243 7.0E-108 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS21280 7a873512e7c27cdb9b47213ed7bac33d 248 PANTHER PTHR30456:SF0 5 248 1.1E-142 T 13-09-2016 THL1_RS18460 8523a04f4dfe4097b9b45af1683e1e4f 309 PANTHER PTHR10992 1 306 1.1E-64 T 13-09-2016 THL1_RS18460 8523a04f4dfe4097b9b45af1683e1e4f 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 132 145 2.9E-18 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS18460 8523a04f4dfe4097b9b45af1683e1e4f 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 146 159 2.9E-18 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS18460 8523a04f4dfe4097b9b45af1683e1e4f 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 250 264 2.9E-18 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS18460 8523a04f4dfe4097b9b45af1683e1e4f 309 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 103 2.9E-18 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS18460 8523a04f4dfe4097b9b45af1683e1e4f 309 Pfam PF12697 Alpha/beta hydrolase family 65 298 2.9E-26 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS18460 8523a04f4dfe4097b9b45af1683e1e4f 309 SUPERFAMILY SSF53474 37 305 5.76E-65 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS18460 8523a04f4dfe4097b9b45af1683e1e4f 309 PRINTS PR00412 Epoxide hydrolase signature 281 303 5.1E-8 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS18460 8523a04f4dfe4097b9b45af1683e1e4f 309 PRINTS PR00412 Epoxide hydrolase signature 146 159 5.1E-8 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS18460 8523a04f4dfe4097b9b45af1683e1e4f 309 PRINTS PR00412 Epoxide hydrolase signature 88 103 5.1E-8 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS18460 8523a04f4dfe4097b9b45af1683e1e4f 309 Gene3D G3DSA:3.40.50.1820 32 305 9.1E-70 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS07550 142e3201170d757b56e4315ae1fe003a 274 PIRSF PIRSF028756 1 273 2.1E-115 T 13-09-2016 IPR016898 Polyphosphate kinase 2 THL1_RS07550 142e3201170d757b56e4315ae1fe003a 274 PANTHER PTHR34383:SF1 19 274 1.6E-136 T 13-09-2016 THL1_RS07550 142e3201170d757b56e4315ae1fe003a 274 Gene3D G3DSA:3.40.50.300 3 260 2.0E-100 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07550 142e3201170d757b56e4315ae1fe003a 274 SUPERFAMILY SSF52540 50 239 7.43E-29 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07550 142e3201170d757b56e4315ae1fe003a 274 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 20 244 3.6E-97 T 13-09-2016 IPR022488 Polyphosphate kinase-2-related THL1_RS07550 142e3201170d757b56e4315ae1fe003a 274 PANTHER PTHR34383 19 274 1.6E-136 T 13-09-2016 THL1_RS07550 142e3201170d757b56e4315ae1fe003a 274 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 21 245 1.4E-106 T 13-09-2016 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 THL1_RS27115 d0089304ada6a67d97e4ab65cdc95a20 134 Gene3D G3DSA:3.10.290.10 10 106 5.8E-36 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS27115 d0089304ada6a67d97e4ab65cdc95a20 134 Pfam PF01479 S4 domain 12 57 1.6E-9 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS27115 d0089304ada6a67d97e4ab65cdc95a20 134 SMART SM00363 12 75 0.0012 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS27115 d0089304ada6a67d97e4ab65cdc95a20 134 PANTHER PTHR11079 6 48 2.4E-20 T 13-09-2016 THL1_RS27115 d0089304ada6a67d97e4ab65cdc95a20 134 SUPERFAMILY SSF55174 11 106 1.57E-27 T 13-09-2016 THL1_RS27115 d0089304ada6a67d97e4ab65cdc95a20 134 PANTHER PTHR11079:SF70 6 48 2.4E-20 T 13-09-2016 THL1_RS27115 d0089304ada6a67d97e4ab65cdc95a20 134 PIRSF PIRSF016821 9 134 1.9E-38 T 13-09-2016 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 THL1_RS18495 7fb70dfc12ea7b9daefb079b154e7ea2 212 PANTHER PTHR30055 2 197 3.0E-66 T 13-09-2016 THL1_RS18495 7fb70dfc12ea7b9daefb079b154e7ea2 212 SUPERFAMILY SSF48498 86 190 4.85E-9 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS18495 7fb70dfc12ea7b9daefb079b154e7ea2 212 Gene3D G3DSA:1.10.357.10 10 194 7.9E-31 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS18495 7fb70dfc12ea7b9daefb079b154e7ea2 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 1.3E-15 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS18495 7fb70dfc12ea7b9daefb079b154e7ea2 212 SUPERFAMILY SSF46689 9 77 5.99E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS18495 7fb70dfc12ea7b9daefb079b154e7ea2 212 PANTHER PTHR30055:SF40 2 197 3.0E-66 T 13-09-2016 THL1_RS18495 7fb70dfc12ea7b9daefb079b154e7ea2 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.9E-10 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS18495 7fb70dfc12ea7b9daefb079b154e7ea2 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.9E-10 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS18495 7fb70dfc12ea7b9daefb079b154e7ea2 212 Pfam PF13305 WHG domain 87 173 4.2E-7 T 13-09-2016 IPR025996 WHG domain THL1_RS10690 4569a37178a9e9b882bb23040e9d3f14 444 Pfam PF11973 NQRA C-terminal domain 260 308 3.5E-19 T 13-09-2016 IPR022615 Na(+)-translocating NADH-quinone reductase subunit A, C-terminal domain GO:0016655|GO:0055114 THL1_RS10690 4569a37178a9e9b882bb23040e9d3f14 444 Pfam PF05896 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) 1 255 1.8E-107 T 13-09-2016 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 THL1_RS10690 4569a37178a9e9b882bb23040e9d3f14 444 PANTHER PTHR37839 1 395 2.6E-176 T 13-09-2016 THL1_RS10690 4569a37178a9e9b882bb23040e9d3f14 444 Hamap MF_00425 Na(+)-translocating NADH-quinone reductase subunit A [nqrA]. 1 444 37.627 T 13-09-2016 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 THL1_RS10690 4569a37178a9e9b882bb23040e9d3f14 444 TIGRFAM TIGR01936 nqrA: NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit 2 395 4.4E-157 T 13-09-2016 IPR008703 Na(+)-translocating NADH-quinone reductase subunit A GO:0006814|GO:0016655|GO:0055114 THL1_RS10690 4569a37178a9e9b882bb23040e9d3f14 444 PANTHER PTHR37839:SF1 1 395 2.6E-176 T 13-09-2016 THL1_RS13245 89e3d3d7d4092af1fb268bec51547dc3 551 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 317 335 2.1E-40 T 13-09-2016 THL1_RS13245 89e3d3d7d4092af1fb268bec51547dc3 551 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 335 351 2.1E-40 T 13-09-2016 THL1_RS13245 89e3d3d7d4092af1fb268bec51547dc3 551 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 2.1E-40 T 13-09-2016 THL1_RS13245 89e3d3d7d4092af1fb268bec51547dc3 551 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 163 178 2.1E-40 T 13-09-2016 THL1_RS13245 89e3d3d7d4092af1fb268bec51547dc3 551 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 2.1E-40 T 13-09-2016 THL1_RS13245 89e3d3d7d4092af1fb268bec51547dc3 551 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 15 37 2.1E-40 T 13-09-2016 THL1_RS13245 89e3d3d7d4092af1fb268bec51547dc3 551 PANTHER PTHR13789 11 385 3.5E-77 T 13-09-2016 THL1_RS13245 89e3d3d7d4092af1fb268bec51547dc3 551 SUPERFAMILY SSF51905 271 384 8.84E-60 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS13245 89e3d3d7d4092af1fb268bec51547dc3 551 SUPERFAMILY SSF51905 14 184 8.84E-60 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS13245 89e3d3d7d4092af1fb268bec51547dc3 551 PANTHER PTHR13789:SF90 11 385 3.5E-77 T 13-09-2016 THL1_RS13245 89e3d3d7d4092af1fb268bec51547dc3 551 Pfam PF01494 FAD binding domain 14 349 1.6E-63 T 13-09-2016 IPR002938 FAD-binding domain GO:0071949 THL1_RS13245 89e3d3d7d4092af1fb268bec51547dc3 551 Gene3D G3DSA:3.50.50.60 272 356 4.0E-50 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS13245 89e3d3d7d4092af1fb268bec51547dc3 551 Gene3D G3DSA:3.50.50.60 14 189 4.0E-50 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS15985 4cbc6fefd37573f0f1ed849c330997cc 115 SUPERFAMILY SSF142906 1 113 4.58E-30 T 13-09-2016 THL1_RS15985 4cbc6fefd37573f0f1ed849c330997cc 115 PANTHER PTHR35145 1 115 3.8E-36 T 13-09-2016 THL1_RS15985 4cbc6fefd37573f0f1ed849c330997cc 115 Pfam PF04237 YjbR 11 99 1.3E-16 T 13-09-2016 IPR007351 Uncharacterised protein YjbR THL1_RS04370 5f9da5fcdd305e11d0f4dc1054dd0c9b 493 Gene3D G3DSA:3.30.1730.10 14 178 5.8E-54 T 13-09-2016 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 THL1_RS04370 5f9da5fcdd305e11d0f4dc1054dd0c9b 493 PANTHER PTHR21234:SF11 258 493 4.9E-117 T 13-09-2016 THL1_RS04370 5f9da5fcdd305e11d0f4dc1054dd0c9b 493 PANTHER PTHR21234:SF11 188 233 4.9E-117 T 13-09-2016 THL1_RS04370 5f9da5fcdd305e11d0f4dc1054dd0c9b 493 Gene3D G3DSA:3.40.50.1580 182 475 2.8E-106 T 13-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 THL1_RS04370 5f9da5fcdd305e11d0f4dc1054dd0c9b 493 SUPERFAMILY SSF53167 16 493 3.53E-146 T 13-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 THL1_RS04370 5f9da5fcdd305e11d0f4dc1054dd0c9b 493 PANTHER PTHR21234 188 233 4.9E-117 T 13-09-2016 IPR018017 Nucleoside phosphorylase THL1_RS04370 5f9da5fcdd305e11d0f4dc1054dd0c9b 493 Pfam PF10423 Bacterial AMP nucleoside phosphorylase N-terminus 19 174 2.1E-48 T 13-09-2016 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 THL1_RS04370 5f9da5fcdd305e11d0f4dc1054dd0c9b 493 TIGRFAM TIGR01717 AMP-nucleosdse: AMP nucleosidase 18 493 1.8E-239 T 13-09-2016 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 THL1_RS04370 5f9da5fcdd305e11d0f4dc1054dd0c9b 493 Pfam PF01048 Phosphorylase superfamily 278 441 1.1E-17 T 13-09-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 THL1_RS04370 5f9da5fcdd305e11d0f4dc1054dd0c9b 493 PANTHER PTHR21234 258 493 4.9E-117 T 13-09-2016 IPR018017 Nucleoside phosphorylase THL1_RS04370 5f9da5fcdd305e11d0f4dc1054dd0c9b 493 Hamap MF_01932 AMP nucleosidase [amn]. 10 493 59.104 T 13-09-2016 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 THL1_RS06545 75e361cefc9dc736f1621735d957ec49 315 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 39 265 8.5E-74 T 13-09-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 THL1_RS06545 75e361cefc9dc736f1621735d957ec49 315 PANTHER PTHR21581 34 314 2.3E-150 T 13-09-2016 THL1_RS06545 75e361cefc9dc736f1621735d957ec49 315 Gene3D G3DSA:3.40.710.10 16 281 9.0E-65 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS06545 75e361cefc9dc736f1621735d957ec49 315 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 120 137 1.8E-14 T 13-09-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THL1_RS06545 75e361cefc9dc736f1621735d957ec49 315 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 70 81 1.8E-14 T 13-09-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THL1_RS06545 75e361cefc9dc736f1621735d957ec49 315 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 147 160 1.8E-14 T 13-09-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THL1_RS06545 75e361cefc9dc736f1621735d957ec49 315 PANTHER PTHR21581:SF8 34 314 2.3E-150 T 13-09-2016 THL1_RS06545 75e361cefc9dc736f1621735d957ec49 315 SUPERFAMILY SSF56601 10 281 4.54E-60 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS22785 1254103b2db2aa326f81de1fa95891ec 367 PANTHER PTHR32347:SF12 1 355 1.6E-89 T 13-09-2016 THL1_RS22785 1254103b2db2aa326f81de1fa95891ec 367 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 36 353 2.5E-76 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS22785 1254103b2db2aa326f81de1fa95891ec 367 Gene3D G3DSA:2.40.50.100 166 197 1.9E-15 T 13-09-2016 THL1_RS22785 1254103b2db2aa326f81de1fa95891ec 367 Gene3D G3DSA:2.40.50.100 61 91 1.9E-15 T 13-09-2016 THL1_RS22785 1254103b2db2aa326f81de1fa95891ec 367 PANTHER PTHR32347 1 355 1.6E-89 T 13-09-2016 THL1_RS22785 1254103b2db2aa326f81de1fa95891ec 367 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 62 261 1.2E-20 T 13-09-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THL1_RS22785 1254103b2db2aa326f81de1fa95891ec 367 SUPERFAMILY SSF111369 48 273 5.75E-21 T 13-09-2016 THL1_RS03325 3300e35bf358aec527257aaf8fa0e6c8 141 Pfam PF02566 OsmC-like protein 34 132 2.5E-19 T 13-09-2016 IPR003718 OsmC/Ohr family THL1_RS03325 3300e35bf358aec527257aaf8fa0e6c8 141 Gene3D G3DSA:3.30.300.20 39 137 5.7E-43 T 13-09-2016 IPR015946 K homology domain-like, alpha/beta THL1_RS03325 3300e35bf358aec527257aaf8fa0e6c8 141 SUPERFAMILY SSF82784 1 137 9.03E-41 T 13-09-2016 IPR003718 OsmC/Ohr family THL1_RS03325 3300e35bf358aec527257aaf8fa0e6c8 141 Gene3D G3DSA:2.20.25.10 1 34 1.6E-16 T 13-09-2016 THL1_RS03325 3300e35bf358aec527257aaf8fa0e6c8 141 PANTHER PTHR34352 1 140 4.3E-52 T 13-09-2016 THL1_RS24690 12f02092774bbefe9b06408a70d4dd9a 238 Gene3D G3DSA:1.10.10.10 155 223 3.2E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS24690 12f02092774bbefe9b06408a70d4dd9a 238 SUPERFAMILY SSF52172 4 127 9.03E-9 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS24690 12f02092774bbefe9b06408a70d4dd9a 238 PANTHER PTHR26402:SF151 8 223 2.6E-30 T 13-09-2016 THL1_RS24690 12f02092774bbefe9b06408a70d4dd9a 238 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 218 2.6E-12 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS24690 12f02092774bbefe9b06408a70d4dd9a 238 PANTHER PTHR26402 8 223 2.6E-30 T 13-09-2016 THL1_RS24690 12f02092774bbefe9b06408a70d4dd9a 238 Gene3D G3DSA:3.40.50.2300 4 127 2.5E-7 T 13-09-2016 THL1_RS24690 12f02092774bbefe9b06408a70d4dd9a 238 SUPERFAMILY SSF46894 152 224 7.14E-16 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS24690 12f02092774bbefe9b06408a70d4dd9a 238 SMART SM00421 159 218 3.0E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS17475 24babce8c08fb9c158b766043a3bd322 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS17475 24babce8c08fb9c158b766043a3bd322 379 SUPERFAMILY SSF56645 1 239 3.01E-67 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS17475 24babce8c08fb9c158b766043a3bd322 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 116 1.6E-24 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS17475 24babce8c08fb9c158b766043a3bd322 379 PANTHER PTHR10909 1 376 2.3E-111 T 13-09-2016 THL1_RS17475 24babce8c08fb9c158b766043a3bd322 379 PANTHER PTHR10909:SF305 1 376 2.3E-111 T 13-09-2016 THL1_RS17475 24babce8c08fb9c158b766043a3bd322 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 2.4E-41 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS17475 24babce8c08fb9c158b766043a3bd322 379 TIGRFAM TIGR03207 cyc_hxne_CoA_dh: cyclohexanecarboxyl-CoA dehydrogenase 6 375 8.8E-186 T 13-09-2016 IPR017620 Cyclohexanecarboxyl-CoA dehydrogenase THL1_RS17475 24babce8c08fb9c158b766043a3bd322 379 Gene3D G3DSA:1.10.540.10 1 119 3.1E-29 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS17475 24babce8c08fb9c158b766043a3bd322 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 216 3.8E-22 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS17475 24babce8c08fb9c158b766043a3bd322 379 Gene3D G3DSA:1.20.140.10 218 377 2.6E-51 T 13-09-2016 THL1_RS17475 24babce8c08fb9c158b766043a3bd322 379 SUPERFAMILY SSF47203 226 377 3.22E-43 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS17475 24babce8c08fb9c158b766043a3bd322 379 Gene3D G3DSA:2.40.110.10 121 217 1.9E-32 T 13-09-2016 THL1_RS08110 d541576ab575b8406cb1135d12f343ea 188 Hamap MF_00146 Deoxycytidine triphosphate deaminase [dcd]. 1 188 28.41 T 13-09-2016 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187|UniPathway: UPA00610 THL1_RS08110 d541576ab575b8406cb1135d12f343ea 188 PANTHER PTHR11241 1 187 1.4E-79 T 13-09-2016 THL1_RS08110 d541576ab575b8406cb1135d12f343ea 188 Pfam PF00692 dUTPase 76 184 2.9E-8 T 13-09-2016 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 THL1_RS08110 d541576ab575b8406cb1135d12f343ea 188 PANTHER PTHR11241:SF1 1 187 1.4E-79 T 13-09-2016 THL1_RS08110 d541576ab575b8406cb1135d12f343ea 188 SUPERFAMILY SSF51283 3 187 5.89E-53 T 13-09-2016 IPR029054 dUTPase-like THL1_RS08110 d541576ab575b8406cb1135d12f343ea 188 Gene3D G3DSA:2.70.40.10 3 187 1.3E-68 T 13-09-2016 IPR029054 dUTPase-like THL1_RS08110 d541576ab575b8406cb1135d12f343ea 188 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 4 187 5.9E-50 T 13-09-2016 IPR011962 Deoxycytidine triphosphate deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187|UniPathway: UPA00610 THL1_RS26805 27651f4cdedf47525fa1277bbe4d2fdd 290 Pfam PF13362 Toprim domain 189 285 3.3E-8 T 13-09-2016 IPR006171 Toprim domain THL1_RS22575 ee7321d27b61122d9441d3393cb39023 377 SUPERFAMILY SSF53756 6 373 1.1E-40 T 13-09-2016 THL1_RS22575 ee7321d27b61122d9441d3393cb39023 377 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 2 368 5.5E-127 T 13-09-2016 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 THL1_RS22575 ee7321d27b61122d9441d3393cb39023 377 PANTHER PTHR30372 1 376 4.0E-130 T 13-09-2016 THL1_RS22575 ee7321d27b61122d9441d3393cb39023 377 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 4 375 42.551 T 13-09-2016 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 THL1_RS22575 ee7321d27b61122d9441d3393cb39023 377 Gene3D G3DSA:3.40.50.2000 159 343 2.0E-8 T 13-09-2016 THL1_RS22575 ee7321d27b61122d9441d3393cb39023 377 Pfam PF02684 Lipid-A-disaccharide synthetase 7 348 1.3E-119 T 13-09-2016 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00500+2.4.1.18|KEGG: 00540+2.4.1.182|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00359 THL1_RS22575 ee7321d27b61122d9441d3393cb39023 377 PANTHER PTHR30372:SF0 1 376 4.0E-130 T 13-09-2016 THL1_RS06700 464b1c46a6e9cc4d902dd44bac0ed745 321 SUPERFAMILY SSF50129 11 137 4.56E-36 T 13-09-2016 IPR011032 GroES-like THL1_RS06700 464b1c46a6e9cc4d902dd44bac0ed745 321 Gene3D G3DSA:3.40.50.720 142 253 7.3E-17 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS06700 464b1c46a6e9cc4d902dd44bac0ed745 321 PANTHER PTHR11695 11 319 1.9E-114 T 13-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 THL1_RS06700 464b1c46a6e9cc4d902dd44bac0ed745 321 PANTHER PTHR11695:SF28 11 319 1.9E-114 T 13-09-2016 THL1_RS06700 464b1c46a6e9cc4d902dd44bac0ed745 321 Gene3D G3DSA:3.90.180.10 11 141 3.4E-46 T 13-09-2016 IPR011032 GroES-like THL1_RS06700 464b1c46a6e9cc4d902dd44bac0ed745 321 Pfam PF00107 Zinc-binding dehydrogenase 147 262 4.0E-17 T 13-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THL1_RS06700 464b1c46a6e9cc4d902dd44bac0ed745 321 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 6 315 5.1E-120 T 13-09-2016 IPR014189 Quinone oxidoreductase PIG3 KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.- THL1_RS06700 464b1c46a6e9cc4d902dd44bac0ed745 321 SMART SM00829 6 314 2.9E-44 T 13-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THL1_RS06700 464b1c46a6e9cc4d902dd44bac0ed745 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 83 4.7E-7 T 13-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THL1_RS06700 464b1c46a6e9cc4d902dd44bac0ed745 321 SUPERFAMILY SSF51735 107 279 9.47E-40 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11495 c45a0e9aa555bb694778764cf5e157ac 339 PANTHER PTHR23024:SF128 87 339 4.7E-100 T 13-09-2016 THL1_RS11495 c45a0e9aa555bb694778764cf5e157ac 339 Pfam PF07859 alpha/beta hydrolase fold 105 311 9.6E-73 T 13-09-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 THL1_RS11495 c45a0e9aa555bb694778764cf5e157ac 339 SUPERFAMILY SSF53474 79 339 2.46E-70 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS11495 c45a0e9aa555bb694778764cf5e157ac 339 Gene3D G3DSA:3.40.50.1820 26 339 1.2E-93 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS11495 c45a0e9aa555bb694778764cf5e157ac 339 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 104 120 - T 13-09-2016 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 THL1_RS11495 c45a0e9aa555bb694778764cf5e157ac 339 PANTHER PTHR23024 87 339 4.7E-100 T 13-09-2016 THL1_RS00285 9c566b28c5029e79c839428f7fd66106 361 PANTHER PTHR35457 3 50 8.5E-68 T 13-09-2016 THL1_RS00285 9c566b28c5029e79c839428f7fd66106 361 PANTHER PTHR35457 236 344 8.5E-68 T 13-09-2016 THL1_RS00285 9c566b28c5029e79c839428f7fd66106 361 PANTHER PTHR35457 66 213 8.5E-68 T 13-09-2016 THL1_RS00285 9c566b28c5029e79c839428f7fd66106 361 PANTHER PTHR35457:SF1 3 50 8.5E-68 T 13-09-2016 THL1_RS00285 9c566b28c5029e79c839428f7fd66106 361 PANTHER PTHR35457:SF1 236 344 8.5E-68 T 13-09-2016 THL1_RS00285 9c566b28c5029e79c839428f7fd66106 361 PANTHER PTHR35457:SF1 66 213 8.5E-68 T 13-09-2016 THL1_RS00285 9c566b28c5029e79c839428f7fd66106 361 Pfam PF02628 Cytochrome oxidase assembly protein 11 320 3.0E-84 T 13-09-2016 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 UniPathway: UPA00269 THL1_RS14425 713bc62e8d56a760271abfc40a22fe8a 287 PANTHER PTHR32089 105 266 1.5E-43 T 13-09-2016 THL1_RS14425 713bc62e8d56a760271abfc40a22fe8a 287 SMART SM00283 63 285 2.8E-11 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS14425 713bc62e8d56a760271abfc40a22fe8a 287 Gene3D G3DSA:1.10.287.950 87 270 2.5E-40 T 13-09-2016 THL1_RS14425 713bc62e8d56a760271abfc40a22fe8a 287 SUPERFAMILY SSF58104 86 281 1.57E-43 T 13-09-2016 THL1_RS14425 713bc62e8d56a760271abfc40a22fe8a 287 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 126 271 8.4E-32 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS09690 94b7785e2bee73f8ab477757f97da4ea 337 Gene3D G3DSA:3.40.718.10 3 336 1.0E-97 T 13-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 THL1_RS09690 94b7785e2bee73f8ab477757f97da4ea 337 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 39 329 2.0E-80 T 13-09-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 THL1_RS09690 94b7785e2bee73f8ab477757f97da4ea 337 PANTHER PTHR30004 4 336 5.7E-200 T 13-09-2016 THL1_RS09690 94b7785e2bee73f8ab477757f97da4ea 337 SUPERFAMILY SSF53659 7 336 3.02E-89 T 13-09-2016 THL1_RS09690 94b7785e2bee73f8ab477757f97da4ea 337 PANTHER PTHR30004:SF3 4 336 5.7E-200 T 13-09-2016 THL1_RS09690 94b7785e2bee73f8ab477757f97da4ea 337 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 5 333 31.576 T 13-09-2016 IPR005255 4-hydroxythreonine-4-phosphate dehydrogenase PdxA GO:0008615|GO:0050570|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00750+1.1.1.262|MetaCyc: PWY-7294|MetaCyc: PWY-7295|UniPathway: UPA00244 THL1_RS18520 3522fa1808402048a60cd7bbf2635322 116 PANTHER PTHR10344 5 107 1.5E-22 T 13-09-2016 THL1_RS18520 3522fa1808402048a60cd7bbf2635322 116 Pfam PF02223 Thymidylate kinase 5 102 6.5E-17 T 13-09-2016 THL1_RS18520 3522fa1808402048a60cd7bbf2635322 116 Gene3D G3DSA:3.40.50.300 5 108 8.2E-29 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18520 3522fa1808402048a60cd7bbf2635322 116 SUPERFAMILY SSF52540 5 112 6.86E-18 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS12005 7606c2a33962cce3c4be521a977caf92 92 SUPERFAMILY SSF47616 33 86 3.41E-9 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS12005 7606c2a33962cce3c4be521a977caf92 92 Gene3D G3DSA:1.20.1050.10 33 86 7.1E-10 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS15840 cdac85c4dd604009c61719c7b6e7d297 505 Pfam PF01425 Amidase 77 487 8.6E-103 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS15840 cdac85c4dd604009c61719c7b6e7d297 505 Gene3D G3DSA:3.90.1300.10 81 504 3.5E-117 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS15840 cdac85c4dd604009c61719c7b6e7d297 505 ProSitePatterns PS00571 Amidases signature. 169 200 - T 13-09-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS15840 cdac85c4dd604009c61719c7b6e7d297 505 PANTHER PTHR11895:SF34 1 501 2.3E-192 T 13-09-2016 THL1_RS15840 cdac85c4dd604009c61719c7b6e7d297 505 PANTHER PTHR11895 1 501 2.3E-192 T 13-09-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS15840 cdac85c4dd604009c61719c7b6e7d297 505 SUPERFAMILY SSF75304 31 503 2.88E-118 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS17425 7a040ebe53e8a3b759153b708f51ba8f 506 SUPERFAMILY SSF51735 1 186 2.47E-53 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS17425 7a040ebe53e8a3b759153b708f51ba8f 506 PANTHER PTHR23309:SF12 1 305 1.2E-178 T 13-09-2016 THL1_RS17425 7a040ebe53e8a3b759153b708f51ba8f 506 PANTHER PTHR23309:SF12 390 499 1.2E-178 T 13-09-2016 THL1_RS17425 7a040ebe53e8a3b759153b708f51ba8f 506 Gene3D G3DSA:1.10.1040.10 413 491 8.1E-16 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS17425 7a040ebe53e8a3b759153b708f51ba8f 506 Gene3D G3DSA:1.10.1040.10 189 284 1.2E-27 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS17425 7a040ebe53e8a3b759153b708f51ba8f 506 PANTHER PTHR23309 1 305 1.2E-178 T 13-09-2016 THL1_RS17425 7a040ebe53e8a3b759153b708f51ba8f 506 PANTHER PTHR23309 390 499 1.2E-178 T 13-09-2016 THL1_RS17425 7a040ebe53e8a3b759153b708f51ba8f 506 Gene3D G3DSA:3.40.50.720 2 188 1.4E-54 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS17425 7a040ebe53e8a3b759153b708f51ba8f 506 SUPERFAMILY SSF48179 412 496 2.81E-15 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS17425 7a040ebe53e8a3b759153b708f51ba8f 506 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 181 2.9E-58 T 13-09-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS17425 7a040ebe53e8a3b759153b708f51ba8f 506 SUPERFAMILY SSF48179 186 291 9.35E-30 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS17425 7a040ebe53e8a3b759153b708f51ba8f 506 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 413 501 3.6E-15 T 13-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS17425 7a040ebe53e8a3b759153b708f51ba8f 506 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 284 1.0E-27 T 13-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS12120 6004d09cb77f72fed4e394e3945decec 328 Gene3D G3DSA:1.20.58.340 252 328 1.4E-27 T 13-09-2016 THL1_RS12120 6004d09cb77f72fed4e394e3945decec 328 PANTHER PTHR21535 22 327 1.8E-97 T 13-09-2016 THL1_RS12120 6004d09cb77f72fed4e394e3945decec 328 SUPERFAMILY SSF144083 263 326 1.06E-19 T 13-09-2016 THL1_RS12120 6004d09cb77f72fed4e394e3945decec 328 SUPERFAMILY SSF143865 23 267 6.28E-31 T 13-09-2016 THL1_RS12120 6004d09cb77f72fed4e394e3945decec 328 PANTHER PTHR21535:SF37 22 327 1.8E-97 T 13-09-2016 THL1_RS12120 6004d09cb77f72fed4e394e3945decec 328 Gene3D G3DSA:3.30.460.20 24 120 7.9E-4 T 13-09-2016 THL1_RS12120 6004d09cb77f72fed4e394e3945decec 328 Pfam PF01544 CorA-like Mg2+ transporter protein 27 324 1.5E-52 T 13-09-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 THL1_RS26660 945a2cd26c9f07164cc3b8625fe254f7 467 Pfam PF00120 Glutamine synthetase, catalytic domain 101 464 7.8E-137 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS26660 945a2cd26c9f07164cc3b8625fe254f7 467 PANTHER PTHR20852 158 467 1.7E-264 T 13-09-2016 THL1_RS26660 945a2cd26c9f07164cc3b8625fe254f7 467 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 12 93 1.9E-30 T 13-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS26660 945a2cd26c9f07164cc3b8625fe254f7 467 ProSitePatterns PS00180 Glutamine synthetase signature 1. 48 66 - T 13-09-2016 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS26660 945a2cd26c9f07164cc3b8625fe254f7 467 SUPERFAMILY SSF55931 100 466 2.26E-135 T 13-09-2016 THL1_RS26660 945a2cd26c9f07164cc3b8625fe254f7 467 Gene3D G3DSA:3.30.590.10 104 453 4.8E-137 T 13-09-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 THL1_RS26660 945a2cd26c9f07164cc3b8625fe254f7 467 PANTHER PTHR20852:SF15 158 467 1.7E-264 T 13-09-2016 THL1_RS26660 945a2cd26c9f07164cc3b8625fe254f7 467 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 257 272 - T 13-09-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS26660 945a2cd26c9f07164cc3b8625fe254f7 467 PANTHER PTHR20852:SF15 1 136 1.7E-264 T 13-09-2016 THL1_RS26660 945a2cd26c9f07164cc3b8625fe254f7 467 SMART SM01230 100 377 1.9E-143 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS26660 945a2cd26c9f07164cc3b8625fe254f7 467 SUPERFAMILY SSF54368 4 98 6.02E-35 T 13-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS26660 945a2cd26c9f07164cc3b8625fe254f7 467 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 384 396 - T 13-09-2016 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS26660 945a2cd26c9f07164cc3b8625fe254f7 467 PANTHER PTHR20852 1 136 1.7E-264 T 13-09-2016 THL1_RS26660 945a2cd26c9f07164cc3b8625fe254f7 467 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 5 466 3.2E-203 T 13-09-2016 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS26660 945a2cd26c9f07164cc3b8625fe254f7 467 Gene3D G3DSA:3.10.20.70 4 103 3.1E-38 T 13-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS24015 4bfc82579b1f0607e50a01c5c2529cdf 200 Gene3D G3DSA:2.170.120.20 100 196 7.9E-31 T 13-09-2016 IPR020057 Ribosomal protein L25, beta domain THL1_RS24015 4bfc82579b1f0607e50a01c5c2529cdf 200 SUPERFAMILY SSF50715 4 197 2.79E-54 T 13-09-2016 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: REACT_71 THL1_RS24015 4bfc82579b1f0607e50a01c5c2529cdf 200 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 102 190 7.3E-30 T 13-09-2016 IPR020057 Ribosomal protein L25, beta domain THL1_RS24015 4bfc82579b1f0607e50a01c5c2529cdf 200 PANTHER PTHR33284 1 200 1.2E-61 T 13-09-2016 THL1_RS24015 4bfc82579b1f0607e50a01c5c2529cdf 200 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 175 2.0E-44 T 13-09-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 THL1_RS24015 4bfc82579b1f0607e50a01c5c2529cdf 200 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 188 31.156 T 13-09-2016 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 THL1_RS24015 4bfc82579b1f0607e50a01c5c2529cdf 200 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 8 97 5.0E-36 T 13-09-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 THL1_RS24015 4bfc82579b1f0607e50a01c5c2529cdf 200 Pfam PF01386 Ribosomal L25p family 6 94 2.1E-26 T 13-09-2016 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 THL1_RS24015 4bfc82579b1f0607e50a01c5c2529cdf 200 Gene3D G3DSA:2.40.240.10 4 97 1.0E-31 T 13-09-2016 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: REACT_71 THL1_RS09020 70e9cb344524f7899c308c7de6a5f2f1 203 SUPERFAMILY SSF52540 12 203 1.95E-72 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09020 70e9cb344524f7899c308c7de6a5f2f1 203 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 34 203 1.6E-59 T 13-09-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 THL1_RS09020 70e9cb344524f7899c308c7de6a5f2f1 203 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 29 203 2.0E-68 T 13-09-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 THL1_RS09020 70e9cb344524f7899c308c7de6a5f2f1 203 Gene3D G3DSA:3.40.50.300 8 203 3.5E-74 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09020 70e9cb344524f7899c308c7de6a5f2f1 203 PANTHER PTHR30069 5 203 3.1E-65 T 13-09-2016 THL1_RS09020 70e9cb344524f7899c308c7de6a5f2f1 203 Pfam PF12557 Cob(I)alamin adenosyltransferase N terminal 1 26 8.6E-10 T 13-09-2016 IPR025826 Cob(I)alamin adenosyltransferase N-terminal domain KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 THL1_RS09020 70e9cb344524f7899c308c7de6a5f2f1 203 PIRSF PIRSF015617 6 203 1.9E-73 T 13-09-2016 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|UniPathway: UPA00148 THL1_RS18310 715731c94c00c9271fa139c787071894 151 SMART SM00347 30 130 8.3E-14 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS18310 715731c94c00c9271fa139c787071894 151 Gene3D G3DSA:1.10.10.10 9 141 4.6E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS18310 715731c94c00c9271fa139c787071894 151 Pfam PF12802 MarR family 36 93 3.5E-11 T 13-09-2016 THL1_RS18310 715731c94c00c9271fa139c787071894 151 SUPERFAMILY SSF46785 9 138 3.64E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19310 70b8f27c0d521ba49911bb920ac66e9d 336 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 314 330 7.9E-6 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS19310 70b8f27c0d521ba49911bb920ac66e9d 336 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 299 314 7.9E-6 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS19310 70b8f27c0d521ba49911bb920ac66e9d 336 Gene3D G3DSA:1.10.10.60 284 332 1.7E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19310 70b8f27c0d521ba49911bb920ac66e9d 336 SUPERFAMILY SSF46689 284 332 1.22E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19310 70b8f27c0d521ba49911bb920ac66e9d 336 Pfam PF12833 Helix-turn-helix domain 255 332 1.1E-19 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS19310 70b8f27c0d521ba49911bb920ac66e9d 336 PANTHER PTHR11019:SF52 208 336 1.7E-30 T 13-09-2016 THL1_RS19310 70b8f27c0d521ba49911bb920ac66e9d 336 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 22 202 5.5E-51 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS19310 70b8f27c0d521ba49911bb920ac66e9d 336 PANTHER PTHR11019 208 336 1.7E-30 T 13-09-2016 THL1_RS19310 70b8f27c0d521ba49911bb920ac66e9d 336 SMART SM00342 248 330 2.5E-26 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS05495 56faaa86c39858ae6030e754a7df45a5 449 PANTHER PTHR10055:SF11 1 337 9.6E-212 T 13-09-2016 THL1_RS05495 56faaa86c39858ae6030e754a7df45a5 449 Gene3D G3DSA:1.10.240.10 214 299 6.4E-26 T 13-09-2016 THL1_RS05495 56faaa86c39858ae6030e754a7df45a5 449 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 204 214 3.5E-19 T 13-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 THL1_RS05495 56faaa86c39858ae6030e754a7df45a5 449 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 15 31 3.5E-19 T 13-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 THL1_RS05495 56faaa86c39858ae6030e754a7df45a5 449 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 150 171 3.5E-19 T 13-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 THL1_RS05495 56faaa86c39858ae6030e754a7df45a5 449 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 67 86 3.5E-19 T 13-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 THL1_RS05495 56faaa86c39858ae6030e754a7df45a5 449 SUPERFAMILY SSF52374 4 333 1.37E-77 T 13-09-2016 THL1_RS05495 56faaa86c39858ae6030e754a7df45a5 449 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 2 334 36.896 T 13-09-2016 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2 THL1_RS05495 56faaa86c39858ae6030e754a7df45a5 449 SUPERFAMILY SSF160113 355 407 1.57E-8 T 13-09-2016 IPR010879 Domain of unknown function DUF1508 THL1_RS05495 56faaa86c39858ae6030e754a7df45a5 449 Pfam PF00579 tRNA synthetases class I (W and Y) 3 281 6.2E-52 T 13-09-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS05495 56faaa86c39858ae6030e754a7df45a5 449 PANTHER PTHR10055 1 337 9.6E-212 T 13-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 THL1_RS05495 56faaa86c39858ae6030e754a7df45a5 449 Gene3D G3DSA:3.40.50.620 3 213 3.3E-72 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS05495 56faaa86c39858ae6030e754a7df45a5 449 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 333 1.6E-95 T 13-09-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 THL1_RS19350 d5c990076157c3949eca896cd3bb22a1 94 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 8 79 1.5E-22 T 13-09-2016 IPR011893 Selenoprotein, Rdx type THL1_RS19350 d5c990076157c3949eca896cd3bb22a1 94 Gene3D G3DSA:3.40.30.10 2 93 3.2E-45 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS19350 d5c990076157c3949eca896cd3bb22a1 94 SUPERFAMILY SSF52833 6 89 4.7E-29 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS19350 d5c990076157c3949eca896cd3bb22a1 94 Pfam PF10262 Rdx family 8 80 1.3E-33 T 13-09-2016 IPR011893 Selenoprotein, Rdx type THL1_RS19350 d5c990076157c3949eca896cd3bb22a1 94 PANTHER PTHR36417:SF1 1 93 8.0E-61 T 13-09-2016 THL1_RS19350 d5c990076157c3949eca896cd3bb22a1 94 PANTHER PTHR36417 1 93 8.0E-61 T 13-09-2016 THL1_RS28115 fa8a2f3138181e942c2cd433a3233634 361 SUPERFAMILY SSF52440 2 94 8.34E-24 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS28115 fa8a2f3138181e942c2cd433a3233634 361 PANTHER PTHR11609:SF8 1 354 6.8E-156 T 13-09-2016 THL1_RS28115 fa8a2f3138181e942c2cd433a3233634 361 Gene3D G3DSA:3.30.1490.20 98 139 5.3E-6 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS28115 fa8a2f3138181e942c2cd433a3233634 361 PANTHER PTHR11609 1 354 6.8E-156 T 13-09-2016 THL1_RS28115 fa8a2f3138181e942c2cd433a3233634 361 Gene3D G3DSA:3.40.50.20 2 97 4.3E-29 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS28115 fa8a2f3138181e942c2cd433a3233634 361 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 2 344 39.768 T 13-09-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 THL1_RS28115 fa8a2f3138181e942c2cd433a3233634 361 Gene3D G3DSA:3.30.470.20 140 359 2.0E-72 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS28115 fa8a2f3138181e942c2cd433a3233634 361 SUPERFAMILY SSF56059 97 292 9.55E-57 T 13-09-2016 THL1_RS28115 fa8a2f3138181e942c2cd433a3233634 361 SUPERFAMILY SSF51246 297 357 1.26E-13 T 13-09-2016 IPR011054 Rudiment single hybrid motif THL1_RS28115 fa8a2f3138181e942c2cd433a3233634 361 Pfam PF02222 ATP-grasp domain 106 272 2.3E-57 T 13-09-2016 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type UniPathway: UPA00074 THL1_RS28115 fa8a2f3138181e942c2cd433a3233634 361 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 2 348 1.2E-110 T 13-09-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 THL1_RS00830 b574a596d27525ce4edecf10870514e8 265 SMART SM00062 41 262 2.7E-89 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS00830 b574a596d27525ce4edecf10870514e8 265 PANTHER PTHR18966:SF189 31 259 9.3E-128 T 13-09-2016 THL1_RS00830 b574a596d27525ce4edecf10870514e8 265 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 64 77 - T 13-09-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 THL1_RS00830 b574a596d27525ce4edecf10870514e8 265 Gene3D G3DSA:3.40.190.10 119 222 3.4E-31 T 13-09-2016 THL1_RS00830 b574a596d27525ce4edecf10870514e8 265 SMART SM00079 41 261 4.1E-5 T 13-09-2016 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 THL1_RS00830 b574a596d27525ce4edecf10870514e8 265 PANTHER PTHR18966 31 259 9.3E-128 T 13-09-2016 THL1_RS00830 b574a596d27525ce4edecf10870514e8 265 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 260 1.9E-75 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS00830 b574a596d27525ce4edecf10870514e8 265 SUPERFAMILY SSF53850 15 262 1.13E-79 T 13-09-2016 THL1_RS00830 b574a596d27525ce4edecf10870514e8 265 Gene3D G3DSA:3.40.190.10 38 118 7.1E-50 T 13-09-2016 THL1_RS00830 b574a596d27525ce4edecf10870514e8 265 Gene3D G3DSA:3.40.190.10 223 263 7.1E-50 T 13-09-2016 THL1_RS08715 cc4d4701282dfc1c5577650732da204a 311 PANTHER PTHR22911 15 307 7.9E-98 T 13-09-2016 THL1_RS08715 cc4d4701282dfc1c5577650732da204a 311 SUPERFAMILY SSF103481 192 294 5.62E-12 T 13-09-2016 THL1_RS08715 cc4d4701282dfc1c5577650732da204a 311 SUPERFAMILY SSF103481 50 147 1.44E-11 T 13-09-2016 THL1_RS08715 cc4d4701282dfc1c5577650732da204a 311 PANTHER PTHR22911:SF63 15 307 7.9E-98 T 13-09-2016 THL1_RS08715 cc4d4701282dfc1c5577650732da204a 311 Pfam PF00892 EamA-like transporter family 14 142 2.3E-15 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS08715 cc4d4701282dfc1c5577650732da204a 311 Pfam PF00892 EamA-like transporter family 157 292 1.9E-19 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS04350 cdd178fbb442009858b0e3cfb52953ba 265 Pfam PF08543 Phosphomethylpyrimidine kinase 17 253 5.6E-69 T 13-09-2016 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase UniPathway: UPA00647 THL1_RS04350 cdd178fbb442009858b0e3cfb52953ba 265 Gene3D G3DSA:3.40.1190.20 8 256 2.5E-71 T 13-09-2016 IPR029056 Ribokinase-like THL1_RS04350 cdd178fbb442009858b0e3cfb52953ba 265 PANTHER PTHR20858:SF17 1 262 1.3E-70 T 13-09-2016 THL1_RS04350 cdd178fbb442009858b0e3cfb52953ba 265 SUPERFAMILY SSF53613 6 256 2.62E-61 T 13-09-2016 IPR029056 Ribokinase-like THL1_RS04350 cdd178fbb442009858b0e3cfb52953ba 265 PANTHER PTHR20858 1 262 1.3E-70 T 13-09-2016 THL1_RS13680 59723d548dbecf522ddac9b23ffd0b7d 304 PANTHER PTHR30537 1 290 8.1E-134 T 13-09-2016 THL1_RS13680 59723d548dbecf522ddac9b23ffd0b7d 304 Gene3D G3DSA:3.40.190.10 180 262 5.1E-36 T 13-09-2016 THL1_RS13680 59723d548dbecf522ddac9b23ffd0b7d 304 SUPERFAMILY SSF46785 7 82 8.84E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13680 59723d548dbecf522ddac9b23ffd0b7d 304 SUPERFAMILY SSF53850 93 296 4.52E-36 T 13-09-2016 THL1_RS13680 59723d548dbecf522ddac9b23ffd0b7d 304 Gene3D G3DSA:1.10.10.10 6 82 2.7E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13680 59723d548dbecf522ddac9b23ffd0b7d 304 Gene3D G3DSA:3.40.190.10 97 179 4.6E-28 T 13-09-2016 THL1_RS13680 59723d548dbecf522ddac9b23ffd0b7d 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 68 3.4E-21 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS13680 59723d548dbecf522ddac9b23ffd0b7d 304 PANTHER PTHR30537:SF15 1 290 8.1E-134 T 13-09-2016 THL1_RS13680 59723d548dbecf522ddac9b23ffd0b7d 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 4.6E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS13680 59723d548dbecf522ddac9b23ffd0b7d 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 4.6E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS13680 59723d548dbecf522ddac9b23ffd0b7d 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 4.6E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS13680 59723d548dbecf522ddac9b23ffd0b7d 304 Pfam PF03466 LysR substrate binding domain 93 291 4.8E-36 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS16540 6fe83f78795aad10954e191afc3e3e7b 542 SUPERFAMILY SSF54373 301 484 1.57E-45 T 13-09-2016 THL1_RS16540 6fe83f78795aad10954e191afc3e3e7b 542 PANTHER PTHR11552:SF51 6 535 5.1E-205 T 13-09-2016 THL1_RS16540 6fe83f78795aad10954e191afc3e3e7b 542 PANTHER PTHR11552 6 535 5.1E-205 T 13-09-2016 THL1_RS16540 6fe83f78795aad10954e191afc3e3e7b 542 Pfam PF05199 GMC oxidoreductase 398 534 1.1E-38 T 13-09-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 THL1_RS16540 6fe83f78795aad10954e191afc3e3e7b 542 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 265 279 - T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS16540 6fe83f78795aad10954e191afc3e3e7b 542 SUPERFAMILY SSF51905 483 540 3.7E-81 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS16540 6fe83f78795aad10954e191afc3e3e7b 542 SUPERFAMILY SSF51905 13 299 3.7E-81 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS16540 6fe83f78795aad10954e191afc3e3e7b 542 Gene3D G3DSA:3.50.50.60 203 313 1.7E-111 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS16540 6fe83f78795aad10954e191afc3e3e7b 542 Gene3D G3DSA:3.50.50.60 479 539 1.7E-111 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS16540 6fe83f78795aad10954e191afc3e3e7b 542 Gene3D G3DSA:3.50.50.60 12 143 1.7E-111 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS16540 6fe83f78795aad10954e191afc3e3e7b 542 Gene3D G3DSA:3.50.50.60 408 422 1.7E-111 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS16540 6fe83f78795aad10954e191afc3e3e7b 542 Pfam PF00732 GMC oxidoreductase 16 307 2.5E-84 T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS16540 6fe83f78795aad10954e191afc3e3e7b 542 PIRSF PIRSF000137 1 542 4.6E-141 T 13-09-2016 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|UniPathway: UPA00529 THL1_RS26405 a6084f331032b235115a01dcd436c098 284 Pfam PF05597 Poly(hydroxyalcanoate) granule associated protein (phasin) 9 139 4.3E-45 T 13-09-2016 IPR008769 Poly granule associated THL1_RS26405 a6084f331032b235115a01dcd436c098 284 PANTHER PTHR38664 10 138 2.9E-16 T 13-09-2016 THL1_RS26405 a6084f331032b235115a01dcd436c098 284 TIGRFAM TIGR01837 PHA_granule_1: poly(hydroxyalkanoate) granule-associated protein 18 139 1.7E-42 T 13-09-2016 IPR008769 Poly granule associated THL1_RS26405 a6084f331032b235115a01dcd436c098 284 PANTHER PTHR38664:SF1 10 138 2.9E-16 T 13-09-2016 THL1_RS18865 8cca169309d733162000a2b99aa64788 72 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 47 2.7E-18 T 13-09-2016 IPR004714 Cytochrome oxidase maturation protein cbb3-type THL1_RS18865 8cca169309d733162000a2b99aa64788 72 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 3 45 2.1E-21 T 13-09-2016 IPR004714 Cytochrome oxidase maturation protein cbb3-type THL1_RS18865 8cca169309d733162000a2b99aa64788 72 PANTHER PTHR41532 2 69 2.3E-21 T 13-09-2016 THL1_RS22835 9bb8818f1f7ee31aaf8633d9c71e076c 155 PANTHER PTHR30204:SF18 1 115 1.1E-49 T 13-09-2016 THL1_RS22835 9bb8818f1f7ee31aaf8633d9c71e076c 155 Gene3D G3DSA:1.10.1660.10 56 131 3.6E-29 T 13-09-2016 THL1_RS22835 9bb8818f1f7ee31aaf8633d9c71e076c 155 Pfam PF13411 MerR HTH family regulatory protein 1 67 1.1E-20 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS22835 9bb8818f1f7ee31aaf8633d9c71e076c 155 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.4E-9 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS22835 9bb8818f1f7ee31aaf8633d9c71e076c 155 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 2.4E-9 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS22835 9bb8818f1f7ee31aaf8633d9c71e076c 155 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.4E-9 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS22835 9bb8818f1f7ee31aaf8633d9c71e076c 155 PANTHER PTHR30204 1 115 1.1E-49 T 13-09-2016 THL1_RS22835 9bb8818f1f7ee31aaf8633d9c71e076c 155 TIGRFAM TIGR02047 CadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator 1 127 2.0E-54 T 13-09-2016 IPR011791 Cd(II)/Pb(II)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0045893|GO:0046872 THL1_RS22835 9bb8818f1f7ee31aaf8633d9c71e076c 155 SUPERFAMILY SSF46955 1 119 1.58E-37 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS22835 9bb8818f1f7ee31aaf8633d9c71e076c 155 SMART SM00422 1 70 3.7E-29 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS22835 9bb8818f1f7ee31aaf8633d9c71e076c 155 Gene3D G3DSA:1.10.1660.10 1 55 2.1E-26 T 13-09-2016 THL1_RS09770 b30346057f6908a123b1dc7b07168fee 438 Gene3D G3DSA:3.50.50.60 20 189 3.2E-43 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS09770 b30346057f6908a123b1dc7b07168fee 438 Gene3D G3DSA:3.50.50.60 387 431 3.2E-43 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS09770 b30346057f6908a123b1dc7b07168fee 438 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 25 211 1.7E-28 T 13-09-2016 THL1_RS09770 b30346057f6908a123b1dc7b07168fee 438 PANTHER PTHR23023 281 420 9.1E-63 T 13-09-2016 THL1_RS09770 b30346057f6908a123b1dc7b07168fee 438 SUPERFAMILY SSF51905 184 422 9.71E-5 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS09770 b30346057f6908a123b1dc7b07168fee 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 3.2E-9 T 13-09-2016 THL1_RS09770 b30346057f6908a123b1dc7b07168fee 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 23 45 3.2E-9 T 13-09-2016 THL1_RS09770 b30346057f6908a123b1dc7b07168fee 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 3.2E-9 T 13-09-2016 THL1_RS09770 b30346057f6908a123b1dc7b07168fee 438 Gene3D G3DSA:3.50.50.60 190 209 1.0E-4 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS09770 b30346057f6908a123b1dc7b07168fee 438 PANTHER PTHR23023:SF4 19 225 9.1E-63 T 13-09-2016 THL1_RS09770 b30346057f6908a123b1dc7b07168fee 438 PANTHER PTHR23023:SF4 281 420 9.1E-63 T 13-09-2016 THL1_RS09770 b30346057f6908a123b1dc7b07168fee 438 SUPERFAMILY SSF51905 21 218 1.07E-35 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS09770 b30346057f6908a123b1dc7b07168fee 438 PANTHER PTHR23023 19 225 9.1E-63 T 13-09-2016 THL1_RS15380 5190db30ec02bf66db5842093a0a59ac 115 PANTHER PTHR30222 1 114 4.7E-35 T 13-09-2016 THL1_RS15380 5190db30ec02bf66db5842093a0a59ac 115 Pfam PF13416 Bacterial extracellular solute-binding protein 9 80 2.2E-11 T 13-09-2016 THL1_RS15380 5190db30ec02bf66db5842093a0a59ac 115 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 14 33 8.9E-17 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS15380 5190db30ec02bf66db5842093a0a59ac 115 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 59 85 8.9E-17 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS15380 5190db30ec02bf66db5842093a0a59ac 115 SUPERFAMILY SSF53850 9 114 4.4E-28 T 13-09-2016 THL1_RS15380 5190db30ec02bf66db5842093a0a59ac 115 Gene3D G3DSA:3.40.190.10 21 80 2.2E-17 T 13-09-2016 THL1_RS15380 5190db30ec02bf66db5842093a0a59ac 115 PANTHER PTHR30222:SF11 1 114 4.7E-35 T 13-09-2016 THL1_RS20260 bcff10ca50880ff6b878d64c03f67e81 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 4.2E-14 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20260 bcff10ca50880ff6b878d64c03f67e81 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 36 67 - T 13-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site THL1_RS20260 bcff10ca50880ff6b878d64c03f67e81 215 Gene3D G3DSA:1.10.357.10 7 211 8.4E-43 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS20260 bcff10ca50880ff6b878d64c03f67e81 215 SUPERFAMILY SSF46689 13 90 4.31E-18 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS20260 bcff10ca50880ff6b878d64c03f67e81 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 2.1E-7 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20260 bcff10ca50880ff6b878d64c03f67e81 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 2.1E-7 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20260 bcff10ca50880ff6b878d64c03f67e81 215 SUPERFAMILY SSF48498 91 212 1.05E-13 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS20260 bcff10ca50880ff6b878d64c03f67e81 215 PANTHER PTHR30055 7 211 1.1E-28 T 13-09-2016 THL1_RS07765 8efe61099d80647ffccc3d84a2555687 79 SUPERFAMILY SSF143120 1 42 1.83E-9 T 13-09-2016 THL1_RS07765 8efe61099d80647ffccc3d84a2555687 79 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 42 7.0E-12 T 13-09-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THL1_RS07765 8efe61099d80647ffccc3d84a2555687 79 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 42 2.2E-9 T 13-09-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THL1_RS07765 8efe61099d80647ffccc3d84a2555687 79 Gene3D G3DSA:3.40.1620.10 3 41 6.3E-9 T 13-09-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THL1_RS03715 66ee49d3959f1e6389fc7c16a4ce7635 408 Gene3D G3DSA:3.30.950.10 107 207 6.6E-28 T 13-09-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 THL1_RS03715 66ee49d3959f1e6389fc7c16a4ce7635 408 Gene3D G3DSA:3.40.50.150 231 400 8.3E-19 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS03715 66ee49d3959f1e6389fc7c16a4ce7635 408 PANTHER PTHR14741 167 361 3.0E-50 T 13-09-2016 THL1_RS03715 66ee49d3959f1e6389fc7c16a4ce7635 408 Gene3D G3DSA:3.40.1010.10 2 106 5.2E-20 T 13-09-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 THL1_RS03715 66ee49d3959f1e6389fc7c16a4ce7635 408 PANTHER PTHR14741:SF34 167 361 3.0E-50 T 13-09-2016 THL1_RS03715 66ee49d3959f1e6389fc7c16a4ce7635 408 SUPERFAMILY SSF53790 4 203 5.63E-35 T 13-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 THL1_RS03715 66ee49d3959f1e6389fc7c16a4ce7635 408 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 240 364 3.3E-4 T 13-09-2016 THL1_RS03715 66ee49d3959f1e6389fc7c16a4ce7635 408 SUPERFAMILY SSF53335 206 383 3.63E-30 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS03715 66ee49d3959f1e6389fc7c16a4ce7635 408 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 230 351 1.7E-34 T 13-09-2016 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377|UniPathway: UPA00148 THL1_RS03715 66ee49d3959f1e6389fc7c16a4ce7635 408 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 7 201 5.9E-44 T 13-09-2016 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 THL1_RS03715 66ee49d3959f1e6389fc7c16a4ce7635 408 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 185 2.7E-16 T 13-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 THL1_RS03715 66ee49d3959f1e6389fc7c16a4ce7635 408 PIRSF PIRSF036428 1 401 1.7E-141 T 13-09-2016 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00148 THL1_RS13980 48f56608d6559d164ba946af7d836461 179 PANTHER PTHR11080 1 166 5.0E-40 T 13-09-2016 THL1_RS13980 48f56608d6559d164ba946af7d836461 179 Gene3D G3DSA:3.40.50.850 1 170 3.5E-45 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS13980 48f56608d6559d164ba946af7d836461 179 SUPERFAMILY SSF52499 2 157 4.71E-48 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS13980 48f56608d6559d164ba946af7d836461 179 Pfam PF00857 Isochorismatase family 3 142 3.1E-37 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS23550 67edd09d49e30ad0a7f3852b0c89f398 468 Pfam PF01266 FAD dependent oxidoreductase 31 393 5.8E-48 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS23550 67edd09d49e30ad0a7f3852b0c89f398 468 PANTHER PTHR13847 1 460 1.3E-170 T 13-09-2016 THL1_RS23550 67edd09d49e30ad0a7f3852b0c89f398 468 Gene3D G3DSA:3.50.50.60 20 114 2.9E-37 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23550 67edd09d49e30ad0a7f3852b0c89f398 468 Gene3D G3DSA:3.50.50.60 178 254 2.9E-37 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23550 67edd09d49e30ad0a7f3852b0c89f398 468 Gene3D G3DSA:3.50.50.60 357 400 2.9E-37 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23550 67edd09d49e30ad0a7f3852b0c89f398 468 SUPERFAMILY SSF51905 182 307 2.27E-41 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23550 67edd09d49e30ad0a7f3852b0c89f398 468 SUPERFAMILY SSF51905 2 124 2.27E-41 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23550 67edd09d49e30ad0a7f3852b0c89f398 468 PANTHER PTHR13847:SF199 1 460 1.3E-170 T 13-09-2016 THL1_RS12620 ce80b627f282f4bd2a2ff85529134bde 131 PANTHER PTHR33570:SF2 1 129 3.3E-66 T 13-09-2016 THL1_RS12620 ce80b627f282f4bd2a2ff85529134bde 131 Gene3D G3DSA:1.20.1290.10 4 126 1.5E-27 T 13-09-2016 IPR029032 AhpD-like THL1_RS12620 ce80b627f282f4bd2a2ff85529134bde 131 Pfam PF02627 Carboxymuconolactone decarboxylase family 36 119 1.1E-24 T 13-09-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS12620 ce80b627f282f4bd2a2ff85529134bde 131 TIGRFAM TIGR02425 decarb_PcaC: 4-carboxymuconolactone decarboxylase 3 124 1.2E-58 T 13-09-2016 IPR012788 4-carboxymuconolactone decarboxylase KEGG: 00362+4.1.1.44|UniPathway: UPA00157 THL1_RS12620 ce80b627f282f4bd2a2ff85529134bde 131 SUPERFAMILY SSF69118 4 126 7.2E-40 T 13-09-2016 IPR029032 AhpD-like THL1_RS12620 ce80b627f282f4bd2a2ff85529134bde 131 PANTHER PTHR33570 1 129 3.3E-66 T 13-09-2016 THL1_RS08265 593d62093c8d7bf95f1c2c155a58dd14 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 9.8E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08265 593d62093c8d7bf95f1c2c155a58dd14 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 9.8E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08265 593d62093c8d7bf95f1c2c155a58dd14 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 9.8E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08265 593d62093c8d7bf95f1c2c155a58dd14 304 Pfam PF03466 LysR substrate binding domain 88 292 1.0E-40 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS08265 593d62093c8d7bf95f1c2c155a58dd14 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.3E-18 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08265 593d62093c8d7bf95f1c2c155a58dd14 304 Gene3D G3DSA:3.40.190.10 178 259 1.3E-21 T 13-09-2016 THL1_RS08265 593d62093c8d7bf95f1c2c155a58dd14 304 PANTHER PTHR30537:SF10 1 300 9.9E-139 T 13-09-2016 THL1_RS08265 593d62093c8d7bf95f1c2c155a58dd14 304 SUPERFAMILY SSF53850 90 295 2.95E-41 T 13-09-2016 THL1_RS08265 593d62093c8d7bf95f1c2c155a58dd14 304 Gene3D G3DSA:1.10.10.10 3 88 3.7E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08265 593d62093c8d7bf95f1c2c155a58dd14 304 Gene3D G3DSA:3.40.190.10 95 177 5.6E-20 T 13-09-2016 THL1_RS08265 593d62093c8d7bf95f1c2c155a58dd14 304 SUPERFAMILY SSF46785 3 88 1.74E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08265 593d62093c8d7bf95f1c2c155a58dd14 304 PANTHER PTHR30537 1 300 9.9E-139 T 13-09-2016 THL1_RS03685 96bd29b0fd18bfab1c0a80304d6f21c5 318 PANTHER PTHR30273 11 318 3.1E-100 T 13-09-2016 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component THL1_RS03685 96bd29b0fd18bfab1c0a80304d6f21c5 318 PIRSF PIRSF018266 5 317 4.0E-80 T 13-09-2016 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component THL1_RS03685 96bd29b0fd18bfab1c0a80304d6f21c5 318 Pfam PF04773 FecR protein 113 203 7.7E-16 T 13-09-2016 IPR006860 FecR protein THL1_RS03685 96bd29b0fd18bfab1c0a80304d6f21c5 318 PANTHER PTHR30273:SF3 11 318 3.1E-100 T 13-09-2016 THL1_RS03685 96bd29b0fd18bfab1c0a80304d6f21c5 318 Pfam PF16220 Domain of unknown function (DUF4880) 16 57 3.3E-12 T 13-09-2016 IPR032623 FecR, N-terminal THL1_RS18675 cf14cfa46d08d02c503dda73d5c76e89 192 Hamap MF_00528 Septum formation protein Maf [maf]. 3 191 28.864 T 13-09-2016 IPR003697 Maf-like protein GO:0005737 THL1_RS18675 cf14cfa46d08d02c503dda73d5c76e89 192 PANTHER PTHR11746:SF102 118 191 3.3E-34 T 13-09-2016 THL1_RS18675 cf14cfa46d08d02c503dda73d5c76e89 192 Pfam PF02545 Maf-like protein 4 184 7.0E-42 T 13-09-2016 IPR003697 Maf-like protein GO:0005737 THL1_RS18675 cf14cfa46d08d02c503dda73d5c76e89 192 PIRSF PIRSF006305 1 191 1.9E-41 T 13-09-2016 IPR003697 Maf-like protein GO:0005737 THL1_RS18675 cf14cfa46d08d02c503dda73d5c76e89 192 PANTHER PTHR11746 118 191 3.3E-34 T 13-09-2016 THL1_RS18675 cf14cfa46d08d02c503dda73d5c76e89 192 SUPERFAMILY SSF52972 2 184 7.19E-57 T 13-09-2016 IPR029001 Inosine triphosphate pyrophosphatase-like THL1_RS18675 cf14cfa46d08d02c503dda73d5c76e89 192 Gene3D G3DSA:3.90.950.10 2 189 1.1E-53 T 13-09-2016 IPR029001 Inosine triphosphate pyrophosphatase-like THL1_RS18675 cf14cfa46d08d02c503dda73d5c76e89 192 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 184 2.8E-49 T 13-09-2016 IPR003697 Maf-like protein GO:0005737 THL1_RS25350 c76d168b15fdcb64ab221e0cd3266527 407 PANTHER PTHR30332:SF1 36 402 6.9E-97 T 13-09-2016 THL1_RS25350 c76d168b15fdcb64ab221e0cd3266527 407 Pfam PF00263 Bacterial type II and III secretion system protein 203 365 1.9E-42 T 13-09-2016 IPR004846 Type II/III secretion system GO:0009306 THL1_RS25350 c76d168b15fdcb64ab221e0cd3266527 407 PRINTS PR00811 Bacterial general secretion pathway protein D signature 199 223 8.6E-11 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS25350 c76d168b15fdcb64ab221e0cd3266527 407 PRINTS PR00811 Bacterial general secretion pathway protein D signature 352 366 8.6E-11 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS25350 c76d168b15fdcb64ab221e0cd3266527 407 PRINTS PR00811 Bacterial general secretion pathway protein D signature 329 347 8.6E-11 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS25350 c76d168b15fdcb64ab221e0cd3266527 407 PANTHER PTHR30332 36 402 6.9E-97 T 13-09-2016 THL1_RS25350 c76d168b15fdcb64ab221e0cd3266527 407 Pfam PF13629 Pilus formation protein N terminal region 34 102 2.8E-18 T 13-09-2016 IPR032789 Pilus formation protein, N-terminal THL1_RS12130 498258484ec83e0cf8ca6bfe88d5a064 186 PANTHER PTHR30529 1 179 4.1E-55 T 13-09-2016 THL1_RS12130 498258484ec83e0cf8ca6bfe88d5a064 186 PANTHER PTHR30529:SF1 1 179 4.1E-55 T 13-09-2016 THL1_RS12130 498258484ec83e0cf8ca6bfe88d5a064 186 SUPERFAMILY SSF81342 1 177 3.3E-35 T 13-09-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 THL1_RS12130 498258484ec83e0cf8ca6bfe88d5a064 186 Pfam PF01292 Prokaryotic cytochrome b561 6 176 4.7E-27 T 13-09-2016 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THL1_RS11045 6b21c61395b6992267383c02ef318212 361 PANTHER PTHR21716 3 359 1.6E-127 T 13-09-2016 IPR002549 Transmembrane protein TqsA-like THL1_RS11045 6b21c61395b6992267383c02ef318212 361 Pfam PF01594 Domain of unknown function DUF20 11 339 4.0E-46 T 13-09-2016 IPR002549 Transmembrane protein TqsA-like THL1_RS11045 6b21c61395b6992267383c02ef318212 361 PANTHER PTHR21716:SF20 3 359 1.6E-127 T 13-09-2016 THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 PRINTS PR00344 Bacterial sensor protein C-terminal signature 834 852 1.9E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 PRINTS PR00344 Bacterial sensor protein C-terminal signature 859 872 1.9E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 PRINTS PR00344 Bacterial sensor protein C-terminal signature 800 814 1.9E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 PRINTS PR00344 Bacterial sensor protein C-terminal signature 818 828 1.9E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 SUPERFAMILY SSF47384 646 720 1.65E-15 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 Pfam PF00512 His Kinase A (phospho-acceptor) domain 652 719 8.8E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 PANTHER PTHR24423:SF562 1 194 3.1E-199 T 13-09-2016 THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 PANTHER PTHR24423:SF562 583 878 3.1E-199 T 13-09-2016 THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 768 873 4.6E-21 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 SMART SM00388 651 719 4.6E-16 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 SMART SM00387 763 875 1.5E-33 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 Gene3D G3DSA:3.30.565.10 721 878 1.5E-37 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 SUPERFAMILY SSF55874 709 877 7.33E-38 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 Gene3D G3DSA:1.20.120.620 386 489 8.7E-27 T 13-09-2016 THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 19 227 4.7E-94 T 13-09-2016 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 Gene3D G3DSA:3.40.50.300 18 225 4.1E-97 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 SUPERFAMILY SSF52402 248 360 1.47E-10 T 13-09-2016 THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 Pfam PF13493 Domain of unknown function (DUF4118) 391 493 6.7E-27 T 13-09-2016 IPR025201 Sensor protein KdpD, transmembrane domain THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 Pfam PF00582 Universal stress protein family 248 357 2.9E-8 T 13-09-2016 IPR006016 UspA GO:0006950 THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 Gene3D G3DSA:1.10.287.130 647 715 1.5E-18 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 PANTHER PTHR24423 583 878 3.1E-199 T 13-09-2016 THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 PANTHER PTHR24423 1 194 3.1E-199 T 13-09-2016 THL1_RS11235 65e4c10c3d9b688519b6e510f958d4ec 882 Gene3D G3DSA:3.40.50.620 244 349 2.7E-12 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS25845 d9fef78ca5e3abce0c15971f14cdcd2d 289 PRINTS PR00721 Stomatin signature 161 179 2.3E-6 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS25845 d9fef78ca5e3abce0c15971f14cdcd2d 289 PRINTS PR00721 Stomatin signature 28 50 2.3E-6 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS25845 d9fef78ca5e3abce0c15971f14cdcd2d 289 PRINTS PR00721 Stomatin signature 115 132 2.3E-6 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS25845 d9fef78ca5e3abce0c15971f14cdcd2d 289 PRINTS PR00721 Stomatin signature 180 201 2.3E-6 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS25845 d9fef78ca5e3abce0c15971f14cdcd2d 289 PANTHER PTHR10264 6 287 6.5E-102 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS25845 d9fef78ca5e3abce0c15971f14cdcd2d 289 PIRSF PIRSF005651 1 289 4.0E-94 T 13-09-2016 IPR010200 HflC GO:0016021|GO:0052547 THL1_RS25845 d9fef78ca5e3abce0c15971f14cdcd2d 289 PANTHER PTHR10264:SF80 6 287 6.5E-102 T 13-09-2016 THL1_RS25845 d9fef78ca5e3abce0c15971f14cdcd2d 289 SMART SM00244 21 185 5.4E-37 T 13-09-2016 IPR001107 Band 7 domain THL1_RS25845 d9fef78ca5e3abce0c15971f14cdcd2d 289 TIGRFAM TIGR01932 hflC: HflC protein 154 284 8.3E-47 T 13-09-2016 IPR010200 HflC GO:0016021|GO:0052547 THL1_RS25845 d9fef78ca5e3abce0c15971f14cdcd2d 289 Pfam PF01145 SPFH domain / Band 7 family 25 200 1.3E-28 T 13-09-2016 IPR001107 Band 7 domain THL1_RS25845 d9fef78ca5e3abce0c15971f14cdcd2d 289 SUPERFAMILY SSF117892 53 192 2.62E-28 T 13-09-2016 IPR001107 Band 7 domain THL1_RS06415 3e8f8d14534d35c3dd4e84aba4bbffed 326 PANTHER PTHR35337 37 323 1.7E-45 T 13-09-2016 THL1_RS06415 3e8f8d14534d35c3dd4e84aba4bbffed 326 Pfam PF01944 Stage II sporulation protein M 111 290 3.1E-36 T 13-09-2016 IPR002798 Stage II sporulation protein M-like THL1_RS02995 f17d716a48cd9e6fb9fb4bd32ad15d0f 168 TIGRFAM TIGR01955 RfaH: transcription elongation factor/antiterminator RfaH 12 165 1.1E-51 T 13-09-2016 IPR010215 Transcription antitermination protein RfaH GO:0006355 THL1_RS02995 f17d716a48cd9e6fb9fb4bd32ad15d0f 168 Gene3D G3DSA:3.30.70.940 10 104 1.3E-19 T 13-09-2016 IPR006645 NusG, N-terminal GO:0006355 THL1_RS02995 f17d716a48cd9e6fb9fb4bd32ad15d0f 168 SMART SM00738 9 107 1.9E-24 T 13-09-2016 IPR006645 NusG, N-terminal GO:0006355 THL1_RS02995 f17d716a48cd9e6fb9fb4bd32ad15d0f 168 Hamap MF_00951 Transcription antitermination protein RfaH [rfaH]. 9 168 41.597 T 13-09-2016 IPR010215 Transcription antitermination protein RfaH GO:0006355 THL1_RS02995 f17d716a48cd9e6fb9fb4bd32ad15d0f 168 PANTHER PTHR30265 7 165 7.1E-36 T 13-09-2016 THL1_RS02995 f17d716a48cd9e6fb9fb4bd32ad15d0f 168 SUPERFAMILY SSF50104 116 167 9.53E-7 T 13-09-2016 IPR008991 Translation protein SH3-like domain THL1_RS02995 f17d716a48cd9e6fb9fb4bd32ad15d0f 168 Gene3D G3DSA:2.30.30.30 114 167 3.1E-6 T 13-09-2016 IPR014722 Ribosomal protein L2 domain 2 THL1_RS02995 f17d716a48cd9e6fb9fb4bd32ad15d0f 168 Pfam PF02357 Transcription termination factor nusG 10 103 8.2E-21 T 13-09-2016 IPR006645 NusG, N-terminal GO:0006355 THL1_RS02995 f17d716a48cd9e6fb9fb4bd32ad15d0f 168 PANTHER PTHR30265:SF3 7 165 7.1E-36 T 13-09-2016 THL1_RS02995 f17d716a48cd9e6fb9fb4bd32ad15d0f 168 SUPERFAMILY SSF82679 10 107 1.96E-27 T 13-09-2016 IPR006645 NusG, N-terminal GO:0006355 THL1_RS12175 e659eb2d9940917c61fce8701c967101 461 Gene3D G3DSA:3.90.226.10 24 127 3.2E-20 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS12175 e659eb2d9940917c61fce8701c967101 461 Gene3D G3DSA:3.90.226.10 189 223 3.2E-20 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS12175 e659eb2d9940917c61fce8701c967101 461 PANTHER PTHR33507:SF1 155 456 8.9E-142 T 13-09-2016 THL1_RS12175 e659eb2d9940917c61fce8701c967101 461 SUPERFAMILY SSF52096 21 213 1.47E-28 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS12175 e659eb2d9940917c61fce8701c967101 461 PANTHER PTHR33507 1 136 8.9E-142 T 13-09-2016 THL1_RS12175 e659eb2d9940917c61fce8701c967101 461 PANTHER PTHR33507 155 456 8.9E-142 T 13-09-2016 THL1_RS12175 e659eb2d9940917c61fce8701c967101 461 PANTHER PTHR33507:SF1 1 136 8.9E-142 T 13-09-2016 THL1_RS12175 e659eb2d9940917c61fce8701c967101 461 SUPERFAMILY SSF141322 385 452 4.58E-8 T 13-09-2016 THL1_RS12175 e659eb2d9940917c61fce8701c967101 461 Gene3D G3DSA:2.40.50.140 398 451 1.0E-9 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS12175 e659eb2d9940917c61fce8701c967101 461 Pfam PF01957 NfeD-like C-terminal, partner-binding 314 452 1.1E-33 T 13-09-2016 IPR002810 NfeD-like, C-terminal domain THL1_RS01735 3ad6b7b2fd6e84abcbccf5340ea4a612 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 5.2E-9 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS01735 3ad6b7b2fd6e84abcbccf5340ea4a612 197 Hamap MF_00768 HTH-type transcriptional regulator BetI [betI]. 1 197 111.342 T 13-09-2016 IPR017757 Transcriptional repressor BetI UniPathway: UPA00529 THL1_RS01735 3ad6b7b2fd6e84abcbccf5340ea4a612 197 PANTHER PTHR30055:SF61 1 197 7.8E-117 T 13-09-2016 THL1_RS01735 3ad6b7b2fd6e84abcbccf5340ea4a612 197 Pfam PF13977 Bacterial transcriptional repressor 84 193 3.7E-35 T 13-09-2016 THL1_RS01735 3ad6b7b2fd6e84abcbccf5340ea4a612 197 SUPERFAMILY SSF46689 5 78 3.54E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01735 3ad6b7b2fd6e84abcbccf5340ea4a612 197 Gene3D G3DSA:1.10.357.10 1 194 2.4E-45 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS01735 3ad6b7b2fd6e84abcbccf5340ea4a612 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 13-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site THL1_RS01735 3ad6b7b2fd6e84abcbccf5340ea4a612 197 PANTHER PTHR30055 1 197 7.8E-117 T 13-09-2016 THL1_RS01735 3ad6b7b2fd6e84abcbccf5340ea4a612 197 SUPERFAMILY SSF48498 82 194 6.16E-23 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS01735 3ad6b7b2fd6e84abcbccf5340ea4a612 197 TIGRFAM TIGR03384 betaine_BetI: transcriptional repressor BetI 2 192 1.6E-78 T 13-09-2016 IPR017757 Transcriptional repressor BetI UniPathway: UPA00529 THL1_RS17580 3a62700418e73b1637f0126ef30ad93b 118 SUPERFAMILY SSF74731 3 117 2.22E-49 T 13-09-2016 THL1_RS17580 3a62700418e73b1637f0126ef30ad93b 118 Pfam PF00453 Ribosomal protein L20 3 109 5.4E-49 T 13-09-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 THL1_RS17580 3a62700418e73b1637f0126ef30ad93b 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 72 3.0E-15 T 13-09-2016 THL1_RS17580 3a62700418e73b1637f0126ef30ad93b 118 PANTHER PTHR10986:SF12 2 117 1.2E-65 T 13-09-2016 THL1_RS17580 3a62700418e73b1637f0126ef30ad93b 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 31.01 T 13-09-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 THL1_RS17580 3a62700418e73b1637f0126ef30ad93b 118 PANTHER PTHR10986 2 117 1.2E-65 T 13-09-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 THL1_RS17580 3a62700418e73b1637f0126ef30ad93b 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.4E-51 T 13-09-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 THL1_RS17580 3a62700418e73b1637f0126ef30ad93b 118 Gene3D G3DSA:1.10.1900.20 55 115 2.9E-30 T 13-09-2016 THL1_RS17580 3a62700418e73b1637f0126ef30ad93b 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 13-09-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 THL1_RS17580 3a62700418e73b1637f0126ef30ad93b 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.0E-40 T 13-09-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 THL1_RS17580 3a62700418e73b1637f0126ef30ad93b 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.0E-40 T 13-09-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 THL1_RS17580 3a62700418e73b1637f0126ef30ad93b 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.0E-40 T 13-09-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 THL1_RS24345 49c708f9cc0dc26560e08d22694ad162 96 Pfam PF11006 Protein of unknown function (DUF2845) 20 92 2.1E-19 T 13-09-2016 IPR021268 Protein of unknown function DUF2845 THL1_RS02680 3bbacbd7025eaa60ff559ccf7a7c5a6b 279 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 16 226 9.6E-68 T 13-09-2016 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181|UniPathway: UPA00865 THL1_RS02680 3bbacbd7025eaa60ff559ccf7a7c5a6b 279 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 97 199 8.7E-11 T 13-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THL1_RS02680 3bbacbd7025eaa60ff559ccf7a7c5a6b 279 Gene3D G3DSA:3.40.50.1000 101 226 3.1E-42 T 13-09-2016 IPR023214 HAD-like domain THL1_RS02680 3bbacbd7025eaa60ff559ccf7a7c5a6b 279 Gene3D G3DSA:3.40.50.1000 14 39 3.1E-42 T 13-09-2016 IPR023214 HAD-like domain THL1_RS02680 3bbacbd7025eaa60ff559ccf7a7c5a6b 279 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 144 160 1.7E-9 T 13-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THL1_RS02680 3bbacbd7025eaa60ff559ccf7a7c5a6b 279 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 162 182 1.7E-9 T 13-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THL1_RS02680 3bbacbd7025eaa60ff559ccf7a7c5a6b 279 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 13 24 1.7E-9 T 13-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THL1_RS02680 3bbacbd7025eaa60ff559ccf7a7c5a6b 279 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 113 126 1.7E-9 T 13-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THL1_RS02680 3bbacbd7025eaa60ff559ccf7a7c5a6b 279 Pfam PF13419 Haloacid dehalogenase-like hydrolase 16 199 2.7E-36 T 13-09-2016 IPR023214 HAD-like domain THL1_RS02680 3bbacbd7025eaa60ff559ccf7a7c5a6b 279 PANTHER PTHR18901 14 227 8.6E-73 T 13-09-2016 THL1_RS02680 3bbacbd7025eaa60ff559ccf7a7c5a6b 279 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 114 194 7.0E-10 T 13-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THL1_RS02680 3bbacbd7025eaa60ff559ccf7a7c5a6b 279 Hamap MF_00495 Phosphoglycolate phosphatase [gph]. 13 230 36.09 T 13-09-2016 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181|UniPathway: UPA00865 THL1_RS02680 3bbacbd7025eaa60ff559ccf7a7c5a6b 279 SUPERFAMILY SSF56784 13 226 1.84E-58 T 13-09-2016 IPR023214 HAD-like domain THL1_RS02680 3bbacbd7025eaa60ff559ccf7a7c5a6b 279 Gene3D G3DSA:1.10.150.240 40 96 9.0E-25 T 13-09-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 THL1_RS02680 3bbacbd7025eaa60ff559ccf7a7c5a6b 279 PANTHER PTHR18901:SF14 14 227 8.6E-73 T 13-09-2016 THL1_RS13465 959c991766a6a5038edeb62d49309375 168 SUPERFAMILY SSF53927 11 167 6.73E-37 T 13-09-2016 IPR016193 Cytidine deaminase-like GO:0003824 THL1_RS13465 959c991766a6a5038edeb62d49309375 168 Gene3D G3DSA:3.40.140.10 13 167 1.2E-38 T 13-09-2016 THL1_RS13465 959c991766a6a5038edeb62d49309375 168 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 66 103 - T 13-09-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 THL1_RS13465 959c991766a6a5038edeb62d49309375 168 PANTHER PTHR11079:SF69 13 167 1.2E-29 T 13-09-2016 THL1_RS13465 959c991766a6a5038edeb62d49309375 168 PANTHER PTHR11079 13 167 1.2E-29 T 13-09-2016 THL1_RS13465 959c991766a6a5038edeb62d49309375 168 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 15 114 7.6E-21 T 13-09-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 THL1_RS15260 25f0aa94438b321ac246e63e06532895 104 Gene3D G3DSA:2.40.50.140 8 86 2.6E-26 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS15260 25f0aa94438b321ac246e63e06532895 104 SUPERFAMILY SSF50249 8 85 5.83E-18 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS15210 25f0aa94438b321ac246e63e06532895 104 Gene3D G3DSA:2.40.50.140 8 86 2.6E-26 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS15210 25f0aa94438b321ac246e63e06532895 104 SUPERFAMILY SSF50249 8 85 5.83E-18 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS15130 25f0aa94438b321ac246e63e06532895 104 Gene3D G3DSA:2.40.50.140 8 86 2.6E-26 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS15130 25f0aa94438b321ac246e63e06532895 104 SUPERFAMILY SSF50249 8 85 5.83E-18 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS24835 9a8b017bad14817fcb387d9705c0cb1c 140 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 9 31 4.0E-8 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS24835 9a8b017bad14817fcb387d9705c0cb1c 140 Gene3D G3DSA:3.30.700.10 11 77 2.4E-8 T 13-09-2016 THL1_RS24835 9a8b017bad14817fcb387d9705c0cb1c 140 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 6 30 3.0E-8 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS24835 9a8b017bad14817fcb387d9705c0cb1c 140 PANTHER PTHR30093 3 140 9.3E-50 T 13-09-2016 THL1_RS24835 9a8b017bad14817fcb387d9705c0cb1c 140 PANTHER PTHR30093:SF9 3 140 9.3E-50 T 13-09-2016 THL1_RS24835 9a8b017bad14817fcb387d9705c0cb1c 140 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 9 140 2.3E-56 T 13-09-2016 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 THL1_RS24835 9a8b017bad14817fcb387d9705c0cb1c 140 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS24835 9a8b017bad14817fcb387d9705c0cb1c 140 Pfam PF08334 Type II secretion system (T2SS), protein G 34 139 3.7E-42 T 13-09-2016 IPR013545 Type II secretion system protein G THL1_RS24835 9a8b017bad14817fcb387d9705c0cb1c 140 SUPERFAMILY SSF54523 36 139 7.85E-36 T 13-09-2016 THL1_RS24835 9a8b017bad14817fcb387d9705c0cb1c 140 PRINTS PR00813 Bacterial general secretion pathway protein G signature 46 64 1.3E-15 T 13-09-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THL1_RS24835 9a8b017bad14817fcb387d9705c0cb1c 140 PRINTS PR00813 Bacterial general secretion pathway protein G signature 10 35 1.3E-15 T 13-09-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THL1_RS13800 7e043070aa060823e03d667c0ebb23c6 495 Gene3D G3DSA:3.40.605.10 16 280 7.5E-99 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS13800 7e043070aa060823e03d667c0ebb23c6 495 SUPERFAMILY SSF53720 14 493 3.01E-170 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS13800 7e043070aa060823e03d667c0ebb23c6 495 Pfam PF00171 Aldehyde dehydrogenase family 32 491 3.2E-172 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS13800 7e043070aa060823e03d667c0ebb23c6 495 Gene3D G3DSA:3.40.309.10 281 466 9.5E-69 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS13800 7e043070aa060823e03d667c0ebb23c6 495 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 267 274 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS13800 7e043070aa060823e03d667c0ebb23c6 495 PANTHER PTHR11699:SF46 1 495 4.0E-239 T 13-09-2016 THL1_RS13800 7e043070aa060823e03d667c0ebb23c6 495 PANTHER PTHR11699 1 495 4.0E-239 T 13-09-2016 THL1_RS13800 7e043070aa060823e03d667c0ebb23c6 495 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS26005 c8ec79234fbf8c848e7252253cd51d1d 627 PANTHER PTHR30557:SF1 131 161 0.0 T 13-09-2016 THL1_RS26005 c8ec79234fbf8c848e7252253cd51d1d 627 PANTHER PTHR30557:SF1 20 97 0.0 T 13-09-2016 THL1_RS26005 c8ec79234fbf8c848e7252253cd51d1d 627 PANTHER PTHR30557:SF1 190 624 0.0 T 13-09-2016 THL1_RS26005 c8ec79234fbf8c848e7252253cd51d1d 627 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 138 591 1.2E-216 T 13-09-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 THL1_RS26005 c8ec79234fbf8c848e7252253cd51d1d 627 Pfam PF01964 Radical SAM ThiC family 139 588 2.0E-199 T 13-09-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 THL1_RS26005 c8ec79234fbf8c848e7252253cd51d1d 627 PANTHER PTHR30557 131 161 0.0 T 13-09-2016 THL1_RS26005 c8ec79234fbf8c848e7252253cd51d1d 627 PANTHER PTHR30557 20 97 0.0 T 13-09-2016 THL1_RS26005 c8ec79234fbf8c848e7252253cd51d1d 627 PANTHER PTHR30557 190 624 0.0 T 13-09-2016 THL1_RS26005 c8ec79234fbf8c848e7252253cd51d1d 627 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 138 593 56.126 T 13-09-2016 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 THL1_RS26005 c8ec79234fbf8c848e7252253cd51d1d 627 Pfam PF13667 ThiC-associated domain 22 99 9.4E-32 T 13-09-2016 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890|UniPathway: UPA00060 THL1_RS12305 f885e95cc8ad6df5bf3c71b7dfe0910d 664 SUPERFAMILY SSF63829 549 628 4.9E-10 T 13-09-2016 THL1_RS12305 f885e95cc8ad6df5bf3c71b7dfe0910d 664 SUPERFAMILY SSF63829 466 523 4.9E-10 T 13-09-2016 THL1_RS12305 f885e95cc8ad6df5bf3c71b7dfe0910d 664 SUPERFAMILY SSF63829 347 427 4.9E-10 T 13-09-2016 THL1_RS12305 f885e95cc8ad6df5bf3c71b7dfe0910d 664 PANTHER PTHR35399:SF2 6 664 7.8E-275 T 13-09-2016 THL1_RS12305 f885e95cc8ad6df5bf3c71b7dfe0910d 664 Pfam PF05787 Bacterial protein of unknown function (DUF839) 79 628 1.8E-186 T 13-09-2016 IPR008557 Protein of unknown function DUF839 THL1_RS12305 f885e95cc8ad6df5bf3c71b7dfe0910d 664 PANTHER PTHR35399 6 664 7.8E-275 T 13-09-2016 THL1_RS12305 f885e95cc8ad6df5bf3c71b7dfe0910d 664 Gene3D G3DSA:2.120.10.30 439 506 8.1E-5 T 13-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like THL1_RS12305 f885e95cc8ad6df5bf3c71b7dfe0910d 664 Gene3D G3DSA:2.120.10.30 550 617 8.1E-5 T 13-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like THL1_RS13590 5596168b354ad37d98316e8573b77a89 373 PANTHER PTHR24220:SF150 14 265 8.4E-140 T 13-09-2016 THL1_RS13590 5596168b354ad37d98316e8573b77a89 373 SMART SM00382 41 228 4.7E-17 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS13590 5596168b354ad37d98316e8573b77a89 373 PANTHER PTHR24220 14 265 8.4E-140 T 13-09-2016 THL1_RS13590 5596168b354ad37d98316e8573b77a89 373 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS13590 5596168b354ad37d98316e8573b77a89 373 Gene3D G3DSA:3.40.50.300 14 256 1.9E-80 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS13590 5596168b354ad37d98316e8573b77a89 373 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 47 368 3.0E-113 T 13-09-2016 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 THL1_RS13590 5596168b354ad37d98316e8573b77a89 373 Pfam PF00005 ABC transporter 32 178 8.0E-34 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS13590 5596168b354ad37d98316e8573b77a89 373 SUPERFAMILY SSF52540 13 260 2.21E-87 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS13590 5596168b354ad37d98316e8573b77a89 373 Pfam PF08402 TOBE domain 295 371 3.8E-17 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS13590 5596168b354ad37d98316e8573b77a89 373 SUPERFAMILY SSF50331 255 368 3.4E-16 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS13305 8443643238b05adeefbc5c58d64fdd23 107 PANTHER PTHR42194:SF1 4 61 4.6E-14 T 13-09-2016 THL1_RS13305 8443643238b05adeefbc5c58d64fdd23 107 Gene3D G3DSA:3.20.20.150 7 61 4.3E-10 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS13305 8443643238b05adeefbc5c58d64fdd23 107 Gene3D G3DSA:3.20.20.150 62 98 7.7E-8 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS13305 8443643238b05adeefbc5c58d64fdd23 107 PANTHER PTHR42194 4 61 4.6E-14 T 13-09-2016 THL1_RS13305 8443643238b05adeefbc5c58d64fdd23 107 Pfam PF05114 Protein of unknown function (DUF692) 9 61 2.5E-8 T 13-09-2016 IPR007801 Uncharacterised protein family UPF0276 THL1_RS24670 5e8547127f83eb9d042868123bc76234 400 Pfam PF07805 HipA-like N-terminal domain 147 224 7.4E-16 T 13-09-2016 IPR012894 HipA, N-terminal subdomain 2 THL1_RS24670 5e8547127f83eb9d042868123bc76234 400 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 21 98 2.8E-7 T 13-09-2016 IPR017508 HipA, N-terminal subdomain 1 THL1_RS24670 5e8547127f83eb9d042868123bc76234 400 Pfam PF13657 HipA N-terminal domain 6 99 5.2E-14 T 13-09-2016 IPR017508 HipA, N-terminal subdomain 1 THL1_RS24670 5e8547127f83eb9d042868123bc76234 400 PANTHER PTHR37419 17 322 1.1E-17 T 13-09-2016 THL1_RS24670 5e8547127f83eb9d042868123bc76234 400 Pfam PF07804 HipA-like C-terminal domain 231 364 8.3E-28 T 13-09-2016 IPR012893 HipA-like, C-terminal THL1_RS03480 db319ef7c926d6e2526c78d8a44a4a2a 166 PANTHER PTHR11560 2 162 4.5E-55 T 13-09-2016 THL1_RS03480 db319ef7c926d6e2526c78d8a44a4a2a 166 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 75 154 4.0E-6 T 13-09-2016 THL1_RS03480 db319ef7c926d6e2526c78d8a44a4a2a 166 SUPERFAMILY SSF160369 4 160 3.14E-48 T 13-09-2016 THL1_RS03480 db319ef7c926d6e2526c78d8a44a4a2a 166 Pfam PF00466 Ribosomal protein L10 5 101 8.7E-26 T 13-09-2016 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 THL1_RS03480 db319ef7c926d6e2526c78d8a44a4a2a 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 27.483 T 13-09-2016 IPR022973 Ribosomal protein L10 THL1_RS03480 db319ef7c926d6e2526c78d8a44a4a2a 166 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 13-09-2016 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS26140 f53e91fe651ee284f753720c11fac124 585 Pfam PF02543 Carbamoyltransferase N-terminus 5 354 1.9E-55 T 13-09-2016 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 THL1_RS26140 f53e91fe651ee284f753720c11fac124 585 SUPERFAMILY SSF53067 22 84 1.18E-12 T 13-09-2016 THL1_RS26140 f53e91fe651ee284f753720c11fac124 585 SUPERFAMILY SSF53067 255 359 1.18E-12 T 13-09-2016 THL1_RS26140 f53e91fe651ee284f753720c11fac124 585 SUPERFAMILY SSF53067 132 218 1.18E-12 T 13-09-2016 THL1_RS26140 f53e91fe651ee284f753720c11fac124 585 Pfam PF16861 Carbamoyltransferase C-terminus 406 575 1.6E-59 T 13-09-2016 IPR031730 Carbamoyltransferase, C-terminal THL1_RS26140 f53e91fe651ee284f753720c11fac124 585 PANTHER PTHR34847 4 582 1.2E-140 T 13-09-2016 THL1_RS07475 bb6b7fa55e7d1c75511861eadfd637a7 328 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 299 328 5.2E-21 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS07475 bb6b7fa55e7d1c75511861eadfd637a7 328 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 270 297 5.2E-21 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS07475 bb6b7fa55e7d1c75511861eadfd637a7 328 Gene3D G3DSA:1.10.287.950 245 326 2.5E-33 T 13-09-2016 THL1_RS07475 bb6b7fa55e7d1c75511861eadfd637a7 328 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 237 325 4.5E-30 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS07475 bb6b7fa55e7d1c75511861eadfd637a7 328 Gene3D G3DSA:3.30.450.20 144 244 1.6E-17 T 13-09-2016 THL1_RS07475 bb6b7fa55e7d1c75511861eadfd637a7 328 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 144 247 8.4E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS07475 bb6b7fa55e7d1c75511861eadfd637a7 328 PANTHER PTHR32089:SF34 263 328 4.0E-38 T 13-09-2016 THL1_RS07475 bb6b7fa55e7d1c75511861eadfd637a7 328 SUPERFAMILY SSF58104 244 325 3.27E-37 T 13-09-2016 THL1_RS07475 bb6b7fa55e7d1c75511861eadfd637a7 328 PANTHER PTHR32089 263 328 4.0E-38 T 13-09-2016 THL1_RS07475 bb6b7fa55e7d1c75511861eadfd637a7 328 SUPERFAMILY SSF55785 141 245 8.2E-16 T 13-09-2016 IPR000014 PAS domain THL1_RS07475 bb6b7fa55e7d1c75511861eadfd637a7 328 Pfam PF08447 PAS fold 147 236 8.3E-20 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 Pfam PF00842 Alanine racemase, C-terminal domain 232 354 5.4E-38 T 13-09-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 Gene3D G3DSA:2.40.37.10 212 355 2.4E-54 T 13-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 PANTHER PTHR30511 1 355 1.1E-161 T 13-09-2016 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 Pfam PF01168 Alanine racemase, N-terminal domain 8 218 3.8E-74 T 13-09-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 SMART SM01005 232 355 4.9E-68 T 13-09-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 SUPERFAMILY SSF50621 228 352 1.43E-44 T 13-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 TIGRFAM TIGR00492 alr: alanine racemase 3 355 8.3E-114 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 SUPERFAMILY SSF51419 8 233 4.97E-74 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 PRINTS PR00992 Alanine racemase signature 25 41 7.9E-63 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 PRINTS PR00992 Alanine racemase signature 120 132 7.9E-63 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 PRINTS PR00992 Alanine racemase signature 248 263 7.9E-63 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 PRINTS PR00992 Alanine racemase signature 338 351 7.9E-63 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 PRINTS PR00992 Alanine racemase signature 265 280 7.9E-63 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 PRINTS PR00992 Alanine racemase signature 286 303 7.9E-63 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 PRINTS PR00992 Alanine racemase signature 60 78 7.9E-63 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 PRINTS PR00992 Alanine racemase signature 191 218 7.9E-63 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 PRINTS PR00992 Alanine racemase signature 154 165 7.9E-63 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 Gene3D G3DSA:3.20.20.10 10 211 1.7E-74 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 30 40 - T 13-09-2016 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 Hamap MF_01201 Alanine racemase. 1 355 36.077 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS27760 800b42a73a4dc5e7fba2b14322501788 355 PANTHER PTHR30511:SF0 1 355 1.1E-161 T 13-09-2016 THL1_RS12525 bd57ea88a4f20b15643d0b5a888c970e 453 SMART SM00984 320 427 1.5E-45 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS12525 bd57ea88a4f20b15643d0b5a888c970e 453 SUPERFAMILY SSF48179 204 301 5.31E-32 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS12525 bd57ea88a4f20b15643d0b5a888c970e 453 PIRSF PIRSF000124 1 442 2.7E-143 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS12525 bd57ea88a4f20b15643d0b5a888c970e 453 Gene3D G3DSA:3.40.50.720 1 199 1.7E-75 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS12525 bd57ea88a4f20b15643d0b5a888c970e 453 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 186 6.7E-63 T 13-09-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS12525 bd57ea88a4f20b15643d0b5a888c970e 453 PIRSF PIRSF500134 1 445 4.4E-179 T 13-09-2016 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|UniPathway: UPA00038 THL1_RS12525 bd57ea88a4f20b15643d0b5a888c970e 453 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 426 1.8E-29 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS12525 bd57ea88a4f20b15643d0b5a888c970e 453 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 204 296 3.7E-37 T 13-09-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 THL1_RS12525 bd57ea88a4f20b15643d0b5a888c970e 453 PANTHER PTHR11374 1 447 8.0E-254 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS12525 bd57ea88a4f20b15643d0b5a888c970e 453 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 423 1.3E-134 T 13-09-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 THL1_RS12525 bd57ea88a4f20b15643d0b5a888c970e 453 Gene3D G3DSA:3.40.50.720 235 447 7.1E-70 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS12525 bd57ea88a4f20b15643d0b5a888c970e 453 PANTHER PTHR11374:SF18 1 447 8.0E-254 T 13-09-2016 THL1_RS12525 bd57ea88a4f20b15643d0b5a888c970e 453 Gene3D G3DSA:1.20.5.100 203 233 6.4E-17 T 13-09-2016 THL1_RS12525 bd57ea88a4f20b15643d0b5a888c970e 453 SUPERFAMILY SSF52413 309 437 1.96E-35 T 13-09-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 THL1_RS12525 bd57ea88a4f20b15643d0b5a888c970e 453 SUPERFAMILY SSF51735 1 195 8.24E-56 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS02035 3b772f4a19d7a7d66d6e7db9051b94af 309 SMART SM00859 3 104 3.0E-12 T 13-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THL1_RS02035 3b772f4a19d7a7d66d6e7db9051b94af 309 PANTHER PTHR32338 2 309 1.3E-87 T 13-09-2016 THL1_RS02035 3b772f4a19d7a7d66d6e7db9051b94af 309 Gene3D G3DSA:3.40.50.720 43 124 1.8E-18 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS02035 3b772f4a19d7a7d66d6e7db9051b94af 309 SUPERFAMILY SSF51735 3 130 4.6E-28 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS02035 3b772f4a19d7a7d66d6e7db9051b94af 309 Gene3D G3DSA:3.30.360.10 125 282 1.6E-34 T 13-09-2016 THL1_RS02035 3b772f4a19d7a7d66d6e7db9051b94af 309 SUPERFAMILY SSF55347 115 282 7.14E-35 T 13-09-2016 THL1_RS02035 3b772f4a19d7a7d66d6e7db9051b94af 309 PANTHER PTHR32338:SF9 2 309 1.3E-87 T 13-09-2016 THL1_RS02035 3b772f4a19d7a7d66d6e7db9051b94af 309 TIGRFAM TIGR01851 argC_other: N-acetyl-gamma-glutamyl-phosphate reductase 3 301 1.1E-99 T 13-09-2016 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS02035 3b772f4a19d7a7d66d6e7db9051b94af 309 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 39 99 3.7E-8 T 13-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THL1_RS21195 79b45cd5cc234db9e9a13d62c80aa2b9 338 SUPERFAMILY SSF55729 1 336 5.01E-121 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS21195 79b45cd5cc234db9e9a13d62c80aa2b9 338 TIGRFAM TIGR03243 arg_catab_AOST: arginine and ornithine succinyltransferase subunits 3 337 1.0E-133 T 13-09-2016 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109|UniPathway: UPA00185 THL1_RS21195 79b45cd5cc234db9e9a13d62c80aa2b9 338 Pfam PF04958 Arginine N-succinyltransferase beta subunit 1 336 6.0E-128 T 13-09-2016 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109|UniPathway: UPA00185 THL1_RS21195 79b45cd5cc234db9e9a13d62c80aa2b9 338 TIGRFAM TIGR03245 arg_AOST_alph: arginine/ornithine succinyltransferase, alpha subunit 3 338 1.3E-164 T 13-09-2016 IPR017651 Arginine/ornithine succinyltransferase, alpha subunit KEGG: 00330+2.3.1.109|UniPathway: UPA00185 THL1_RS21195 79b45cd5cc234db9e9a13d62c80aa2b9 338 PANTHER PTHR30420:SF3 1 338 1.4E-246 T 13-09-2016 THL1_RS21195 79b45cd5cc234db9e9a13d62c80aa2b9 338 PANTHER PTHR30420 1 338 1.4E-246 T 13-09-2016 THL1_RS21195 79b45cd5cc234db9e9a13d62c80aa2b9 338 Gene3D G3DSA:2.40.40.20 275 338 1.4E-28 T 13-09-2016 THL1_RS28385 df4a95fad180b6d0fe6dd91857305d25 139 PANTHER PTHR33823 14 137 1.4E-27 T 13-09-2016 THL1_RS28385 df4a95fad180b6d0fe6dd91857305d25 139 SUPERFAMILY SSF109635 6 96 1.57E-22 T 13-09-2016 THL1_RS28385 df4a95fad180b6d0fe6dd91857305d25 139 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 101 125 - T 13-09-2016 IPR020458 Zinc finger, DksA/TraR C4-type conserved site THL1_RS28385 df4a95fad180b6d0fe6dd91857305d25 139 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 96 131 1.8E-10 T 13-09-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 THL1_RS28385 df4a95fad180b6d0fe6dd91857305d25 139 SUPERFAMILY SSF57716 98 136 9.12E-9 T 13-09-2016 THL1_RS28385 df4a95fad180b6d0fe6dd91857305d25 139 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 20 128 3.6E-35 T 13-09-2016 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 THL1_RS28385 df4a95fad180b6d0fe6dd91857305d25 139 PANTHER PTHR33823:SF2 14 137 1.4E-27 T 13-09-2016 THL1_RS19510 577d5645c68b469cdae3601362a94101 248 Pfam PF04539 Sigma-70 region 3 103 171 3.6E-11 T 13-09-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS19510 577d5645c68b469cdae3601362a94101 248 Pfam PF04545 Sigma-70, region 4 191 240 1.8E-18 T 13-09-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS19510 577d5645c68b469cdae3601362a94101 248 SUPERFAMILY SSF88659 173 245 2.99E-20 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS19510 577d5645c68b469cdae3601362a94101 248 Gene3D G3DSA:1.10.10.10 179 244 4.8E-15 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19510 577d5645c68b469cdae3601362a94101 248 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 22 242 1.0E-83 T 13-09-2016 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THL1_RS19510 577d5645c68b469cdae3601362a94101 248 Gene3D G3DSA:1.10.10.10 96 140 2.1E-5 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19510 577d5645c68b469cdae3601362a94101 248 Gene3D G3DSA:1.10.601.10 13 86 8.7E-18 T 13-09-2016 THL1_RS19510 577d5645c68b469cdae3601362a94101 248 SUPERFAMILY SSF88659 96 162 8.28E-13 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS19510 577d5645c68b469cdae3601362a94101 248 Pfam PF04542 Sigma-70 region 2 22 94 1.9E-18 T 13-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS19510 577d5645c68b469cdae3601362a94101 248 SUPERFAMILY SSF88946 11 94 2.75E-25 T 13-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS19510 577d5645c68b469cdae3601362a94101 248 PIRSF PIRSF000770 2 246 2.6E-36 T 13-09-2016 IPR016263 RNA polymerase sporulation-specific sigma factor GO:0003677|GO:0006351|GO:0016987|GO:0030435 THL1_RS19510 577d5645c68b469cdae3601362a94101 248 Hamap MF_00962 RNA polymerase sigma factor FliA [fliA]. 8 245 66.7 T 13-09-2016 IPR028617 RNA polymerase sigma factor FliA GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 THL1_RS19510 577d5645c68b469cdae3601362a94101 248 PANTHER PTHR30385:SF7 16 248 2.5E-76 T 13-09-2016 THL1_RS19510 577d5645c68b469cdae3601362a94101 248 PRINTS PR00046 Major sigma-70 factor signature 195 207 3.8E-11 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS19510 577d5645c68b469cdae3601362a94101 248 PRINTS PR00046 Major sigma-70 factor signature 49 62 3.8E-11 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS19510 577d5645c68b469cdae3601362a94101 248 PRINTS PR00046 Major sigma-70 factor signature 212 227 3.8E-11 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS19510 577d5645c68b469cdae3601362a94101 248 PRINTS PR00046 Major sigma-70 factor signature 227 238 3.8E-11 T 13-09-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS19510 577d5645c68b469cdae3601362a94101 248 PANTHER PTHR30385 16 248 2.5E-76 T 13-09-2016 THL1_RS19510 577d5645c68b469cdae3601362a94101 248 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 242 1.0E-36 T 13-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS25165 6825da46a6879ae8e71b9d943bc11201 425 PANTHER PTHR18919 2 425 3.4E-177 T 13-09-2016 THL1_RS25165 6825da46a6879ae8e71b9d943bc11201 425 PANTHER PTHR18919:SF5 2 425 3.4E-177 T 13-09-2016 THL1_RS25165 6825da46a6879ae8e71b9d943bc11201 425 Gene3D G3DSA:3.40.47.10 7 126 5.1E-46 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS25165 6825da46a6879ae8e71b9d943bc11201 425 Gene3D G3DSA:3.40.47.10 213 287 5.1E-46 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS25165 6825da46a6879ae8e71b9d943bc11201 425 Gene3D G3DSA:3.40.47.10 169 212 3.4E-40 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS25165 6825da46a6879ae8e71b9d943bc11201 425 Gene3D G3DSA:3.40.47.10 293 424 3.4E-40 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS25165 6825da46a6879ae8e71b9d943bc11201 425 SUPERFAMILY SSF53901 293 424 1.59E-26 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS25165 6825da46a6879ae8e71b9d943bc11201 425 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 9 424 2.2E-111 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS25165 6825da46a6879ae8e71b9d943bc11201 425 Pfam PF02803 Thiolase, C-terminal domain 285 425 1.9E-27 T 13-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THL1_RS25165 6825da46a6879ae8e71b9d943bc11201 425 SUPERFAMILY SSF53901 7 282 7.68E-55 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS25165 6825da46a6879ae8e71b9d943bc11201 425 PIRSF PIRSF000429 1 425 1.0E-95 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS25165 6825da46a6879ae8e71b9d943bc11201 425 Pfam PF00108 Thiolase, N-terminal domain 7 275 4.3E-48 T 13-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THL1_RS15960 ba4e94c7b72b0700bf5058a4b0615b53 529 SUPERFAMILY SSF52540 6 237 2.97E-42 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15960 ba4e94c7b72b0700bf5058a4b0615b53 529 Gene3D G3DSA:3.40.50.300 321 526 4.8E-42 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15960 ba4e94c7b72b0700bf5058a4b0615b53 529 Pfam PF12848 ABC transporter 224 298 3.4E-21 T 13-09-2016 IPR032781 ABC-transporter extension domain THL1_RS15960 ba4e94c7b72b0700bf5058a4b0615b53 529 PANTHER PTHR19211 2 525 0.0 T 13-09-2016 THL1_RS15960 ba4e94c7b72b0700bf5058a4b0615b53 529 Gene3D G3DSA:3.40.50.300 2 270 6.5E-45 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15960 ba4e94c7b72b0700bf5058a4b0615b53 529 SMART SM00382 26 245 2.0E-9 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS15960 ba4e94c7b72b0700bf5058a4b0615b53 529 SMART SM00382 344 511 4.0E-13 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS15960 ba4e94c7b72b0700bf5058a4b0615b53 529 SUPERFAMILY SSF52540 297 526 9.28E-45 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15960 ba4e94c7b72b0700bf5058a4b0615b53 529 PANTHER PTHR19211:SF38 2 525 0.0 T 13-09-2016 THL1_RS15960 ba4e94c7b72b0700bf5058a4b0615b53 529 Pfam PF00005 ABC transporter 18 184 3.5E-17 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS15960 ba4e94c7b72b0700bf5058a4b0615b53 529 Pfam PF00005 ABC transporter 336 465 1.1E-20 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 457 9.0E-49 T 13-09-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 PANTHER PTHR11451 397 571 7.2E-159 T 13-09-2016 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 PANTHER PTHR11451 4 244 7.2E-159 T 13-09-2016 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 566 4.3E-252 T 13-09-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 PANTHER PTHR11451:SF3 397 571 7.2E-159 T 13-09-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 PANTHER PTHR11451:SF3 4 244 7.2E-159 T 13-09-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 SUPERFAMILY SSF52954 461 569 1.06E-28 T 13-09-2016 IPR004154 Anticodon-binding THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.3E-19 T 13-09-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.3E-19 T 13-09-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.3E-19 T 13-09-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.3E-19 T 13-09-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 Gene3D G3DSA:3.40.50.800 470 568 1.9E-27 T 13-09-2016 IPR004154 Anticodon-binding THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 SUPERFAMILY SSF55826 218 388 1.57E-31 T 13-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 SUPERFAMILY SSF55681 405 476 1.01E-108 T 13-09-2016 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 SUPERFAMILY SSF55681 10 237 1.01E-108 T 13-09-2016 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 Pfam PF03129 Anticodon binding domain 473 567 2.0E-16 T 13-09-2016 IPR004154 Anticodon-binding THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 Pfam PF04073 Aminoacyl-tRNA editing domain 257 375 6.1E-26 T 13-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 Gene3D G3DSA:3.90.960.10 254 386 4.8E-30 T 13-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 PIRSF PIRSF001535 1 571 1.1E-269 T 13-09-2016 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 570 42.589 T 13-09-2016 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 Gene3D G3DSA:3.30.930.10 10 234 1.6E-107 T 13-09-2016 THL1_RS22185 f47076e1d9b8252ca981d2315bfc885f 571 Gene3D G3DSA:3.30.930.10 387 469 1.6E-107 T 13-09-2016 THL1_RS23785 56630663c32cccfd6634b7423bfd48ee 194 Pfam PF01169 Uncharacterized protein family UPF0016 10 80 4.0E-19 T 13-09-2016 IPR001727 Uncharacterised protein family UPF0016 GO:0016020 THL1_RS23785 56630663c32cccfd6634b7423bfd48ee 194 Pfam PF01169 Uncharacterized protein family UPF0016 105 179 7.4E-21 T 13-09-2016 IPR001727 Uncharacterised protein family UPF0016 GO:0016020 THL1_RS23785 56630663c32cccfd6634b7423bfd48ee 194 PANTHER PTHR12608 10 191 1.6E-37 T 13-09-2016 IPR001727 Uncharacterised protein family UPF0016 GO:0016020 THL1_RS19610 8463def3381ced0032028239415a087f 596 PANTHER PTHR30046:SF0 18 343 6.8E-195 T 13-09-2016 THL1_RS19610 8463def3381ced0032028239415a087f 596 PIRSF PIRSF004862 21 596 2.0E-139 T 13-09-2016 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 THL1_RS19610 8463def3381ced0032028239415a087f 596 PANTHER PTHR30046 18 343 6.8E-195 T 13-09-2016 THL1_RS19610 8463def3381ced0032028239415a087f 596 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 31 595 1.6E-90 T 13-09-2016 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 THL1_RS19610 8463def3381ced0032028239415a087f 596 PANTHER PTHR30046:SF0 375 596 6.8E-195 T 13-09-2016 THL1_RS19610 8463def3381ced0032028239415a087f 596 PANTHER PTHR30046 375 596 6.8E-195 T 13-09-2016 THL1_RS19610 8463def3381ced0032028239415a087f 596 PRINTS PR01009 Flagellar M-ring protein signature 392 416 2.4E-39 T 13-09-2016 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 THL1_RS19610 8463def3381ced0032028239415a087f 596 PRINTS PR01009 Flagellar M-ring protein signature 141 159 2.4E-39 T 13-09-2016 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 THL1_RS19610 8463def3381ced0032028239415a087f 596 PRINTS PR01009 Flagellar M-ring protein signature 286 304 2.4E-39 T 13-09-2016 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 THL1_RS19610 8463def3381ced0032028239415a087f 596 PRINTS PR01009 Flagellar M-ring protein signature 173 187 2.4E-39 T 13-09-2016 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 THL1_RS19610 8463def3381ced0032028239415a087f 596 PRINTS PR01009 Flagellar M-ring protein signature 216 234 2.4E-39 T 13-09-2016 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 THL1_RS19610 8463def3381ced0032028239415a087f 596 Pfam PF01514 Secretory protein of YscJ/FliF family 49 240 2.0E-71 T 13-09-2016 IPR006182 Secretory protein YscJ/FliF THL1_RS19610 8463def3381ced0032028239415a087f 596 Pfam PF08345 Flagellar M-ring protein C-terminal 273 469 2.6E-46 T 13-09-2016 IPR013556 Flagellar M-ring C-terminal THL1_RS08945 927aed792d3f0fcfd01fff541d33dbaa 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS08945 927aed792d3f0fcfd01fff541d33dbaa 379 Gene3D G3DSA:1.20.140.10 218 377 4.8E-54 T 13-09-2016 THL1_RS08945 927aed792d3f0fcfd01fff541d33dbaa 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 119 3.9E-29 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS08945 927aed792d3f0fcfd01fff541d33dbaa 379 SUPERFAMILY SSF47203 230 377 5.15E-45 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS08945 927aed792d3f0fcfd01fff541d33dbaa 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 217 1.6E-23 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS08945 927aed792d3f0fcfd01fff541d33dbaa 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 377 3.9E-39 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS08945 927aed792d3f0fcfd01fff541d33dbaa 379 Gene3D G3DSA:1.10.540.10 5 120 2.7E-31 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS08945 927aed792d3f0fcfd01fff541d33dbaa 379 Gene3D G3DSA:2.40.110.10 123 217 4.8E-39 T 13-09-2016 THL1_RS08945 927aed792d3f0fcfd01fff541d33dbaa 379 PANTHER PTHR10909 3 377 3.2E-238 T 13-09-2016 THL1_RS08945 927aed792d3f0fcfd01fff541d33dbaa 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS08945 927aed792d3f0fcfd01fff541d33dbaa 379 PANTHER PTHR10909:SF190 3 377 3.2E-238 T 13-09-2016 THL1_RS08945 927aed792d3f0fcfd01fff541d33dbaa 379 SUPERFAMILY SSF56645 4 241 4.19E-79 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS18490 c0775ec2f4b47614ba85235135ab61cd 322 Pfam PF04055 Radical SAM superfamily 15 174 3.5E-23 T 13-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 THL1_RS18490 c0775ec2f4b47614ba85235135ab61cd 322 Pfam PF06463 Molybdenum Cofactor Synthesis C 181 307 6.1E-28 T 13-09-2016 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.18|MetaCyc: PWY-6823|UniPathway: UPA00344 THL1_RS18490 c0775ec2f4b47614ba85235135ab61cd 322 SMART SM00729 11 212 1.8E-7 T 13-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THL1_RS18490 c0775ec2f4b47614ba85235135ab61cd 322 SUPERFAMILY SSF102114 3 290 4.58E-60 T 13-09-2016 THL1_RS18490 c0775ec2f4b47614ba85235135ab61cd 322 PANTHER PTHR22960 1 275 2.7E-78 T 13-09-2016 THL1_RS18490 c0775ec2f4b47614ba85235135ab61cd 322 Gene3D G3DSA:3.20.20.70 3 287 1.5E-59 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS18490 c0775ec2f4b47614ba85235135ab61cd 322 Pfam PF13353 4Fe-4S single cluster domain 15 100 4.8E-6 T 13-09-2016 THL1_RS02890 584fb7f05d979a774ae3576426cfee07 451 Pfam PF00072 Response regulator receiver domain 14 123 1.3E-22 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02890 584fb7f05d979a774ae3576426cfee07 451 Pfam PF13487 HD domain 258 318 2.0E-17 T 13-09-2016 THL1_RS02890 584fb7f05d979a774ae3576426cfee07 451 Gene3D G3DSA:3.40.50.2300 12 140 5.4E-33 T 13-09-2016 THL1_RS02890 584fb7f05d979a774ae3576426cfee07 451 SUPERFAMILY SSF52172 10 174 1.57E-35 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS02890 584fb7f05d979a774ae3576426cfee07 451 PANTHER PTHR26402 11 365 1.2E-46 T 13-09-2016 THL1_RS02890 584fb7f05d979a774ae3576426cfee07 451 SUPERFAMILY SSF109604 210 365 4.08E-9 T 13-09-2016 THL1_RS02890 584fb7f05d979a774ae3576426cfee07 451 SMART SM00448 11 123 4.6E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02890 584fb7f05d979a774ae3576426cfee07 451 PANTHER PTHR26402:SF515 11 365 1.2E-46 T 13-09-2016 THL1_RS11445 852909f5394dad1114f12889f60faa93 316 Gene3D G3DSA:1.10.10.10 10 92 8.9E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11445 852909f5394dad1114f12889f60faa93 316 PANTHER PTHR30579:SF3 5 312 1.5E-69 T 13-09-2016 THL1_RS11445 852909f5394dad1114f12889f60faa93 316 SUPERFAMILY SSF53850 98 296 4.21E-35 T 13-09-2016 THL1_RS11445 852909f5394dad1114f12889f60faa93 316 Gene3D G3DSA:3.40.190.10 101 200 8.2E-20 T 13-09-2016 THL1_RS11445 852909f5394dad1114f12889f60faa93 316 PANTHER PTHR30579 5 312 1.5E-69 T 13-09-2016 THL1_RS11445 852909f5394dad1114f12889f60faa93 316 Pfam PF03466 LysR substrate binding domain 98 293 4.5E-32 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS11445 852909f5394dad1114f12889f60faa93 316 SUPERFAMILY SSF46785 10 120 2.43E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11445 852909f5394dad1114f12889f60faa93 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 72 4.3E-16 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS27605 363ff827e021177431006fa9b5818391 535 PANTHER PTHR22855:SF35 1 535 0.0 T 13-09-2016 THL1_RS27605 363ff827e021177431006fa9b5818391 535 SUPERFAMILY SSF52096 237 517 2.94E-90 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS27605 363ff827e021177431006fa9b5818391 535 Pfam PF01039 Carboxyl transferase domain 48 524 4.7E-155 T 13-09-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS27605 363ff827e021177431006fa9b5818391 535 SUPERFAMILY SSF52096 23 270 3.13E-75 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS27605 363ff827e021177431006fa9b5818391 535 PANTHER PTHR22855 1 535 0.0 T 13-09-2016 THL1_RS27605 363ff827e021177431006fa9b5818391 535 Gene3D G3DSA:3.90.226.10 278 530 4.0E-92 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS27605 363ff827e021177431006fa9b5818391 535 Gene3D G3DSA:3.90.226.10 36 272 2.0E-83 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS25895 cd8c8cf571d878be52b393e0bcfc2e95 180 PANTHER PTHR11046 1 180 1.2E-118 T 13-09-2016 THL1_RS25895 cd8c8cf571d878be52b393e0bcfc2e95 180 Gene3D G3DSA:3.30.420.10 5 179 9.7E-74 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS25895 cd8c8cf571d878be52b393e0bcfc2e95 180 SMART SM00479 6 179 6.6E-23 T 13-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III THL1_RS25895 cd8c8cf571d878be52b393e0bcfc2e95 180 SUPERFAMILY SSF53098 1 179 4.3E-48 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS25895 cd8c8cf571d878be52b393e0bcfc2e95 180 Pfam PF00929 Exonuclease 8 169 2.1E-34 T 13-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III THL1_RS25895 cd8c8cf571d878be52b393e0bcfc2e95 180 PANTHER PTHR11046:SF1 1 180 1.2E-118 T 13-09-2016 THL1_RS25895 cd8c8cf571d878be52b393e0bcfc2e95 180 Hamap MF_00045 Oligoribonuclease [orn]. 2 180 43.722 T 13-09-2016 IPR022894 Oligoribonuclease GO:0016788 THL1_RS23520 4d4f64eec98755d289c9f903ca144fdf 339 SUPERFAMILY SSF51735 138 335 3.4E-46 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23520 4d4f64eec98755d289c9f903ca144fdf 339 PIRSF PIRSF000188 1 338 5.4E-138 T 13-09-2016 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 THL1_RS23520 4d4f64eec98755d289c9f903ca144fdf 339 Gene3D G3DSA:3.40.192.10 1 141 1.5E-55 T 13-09-2016 THL1_RS23520 4d4f64eec98755d289c9f903ca144fdf 339 Gene3D G3DSA:3.40.50.720 142 329 3.2E-46 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23520 4d4f64eec98755d289c9f903ca144fdf 339 PANTHER PTHR11606 1 289 4.5E-108 T 13-09-2016 THL1_RS23520 4d4f64eec98755d289c9f903ca144fdf 339 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 22 128 1.3E-19 T 13-09-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 THL1_RS23520 4d4f64eec98755d289c9f903ca144fdf 339 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 212 290 1.8E-8 T 13-09-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 THL1_RS23520 4d4f64eec98755d289c9f903ca144fdf 339 PANTHER PTHR11606:SF3 1 289 4.5E-108 T 13-09-2016 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 THL1_RS23520 4d4f64eec98755d289c9f903ca144fdf 339 SUPERFAMILY SSF53223 2 134 9.6E-40 T 13-09-2016 THL1_RS23520 4d4f64eec98755d289c9f903ca144fdf 339 SMART SM00839 138 339 4.2E-65 T 13-09-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 THL1_RS23520 4d4f64eec98755d289c9f903ca144fdf 339 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 280 291 1.0E-11 T 13-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 THL1_RS23520 4d4f64eec98755d289c9f903ca144fdf 339 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 64 78 1.0E-11 T 13-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 THL1_RS23520 4d4f64eec98755d289c9f903ca144fdf 339 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 170 190 1.0E-11 T 13-09-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 685 701 - T 13-09-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 PANTHER PTHR11493 424 840 5.6E-273 T 13-09-2016 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 PANTHER PTHR11493:SF52 424 840 5.6E-273 T 13-09-2016 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 Gene3D G3DSA:3.30.413.10 638 775 2.1E-33 T 13-09-2016 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 638 759 1.6E-18 T 13-09-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 PANTHER PTHR11493:SF52 9 262 5.6E-273 T 13-09-2016 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 566 628 3.0E-11 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 SUPERFAMILY SSF51905 9 195 6.41E-39 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 SUPERFAMILY SSF56014 639 814 2.09E-50 T 13-09-2016 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 14 292 1.4E-43 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 Gene3D G3DSA:3.50.50.60 238 319 1.1E-13 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 Pfam PF04324 BFD-like [2Fe-2S] binding domain 428 476 6.6E-9 T 13-09-2016 IPR007419 BFD-like [2Fe-2S]-binding domain THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 Gene3D G3DSA:3.50.50.60 9 114 1.9E-23 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 PIRSF PIRSF037149 6 841 0.0 T 13-09-2016 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 SUPERFAMILY SSF55124 512 647 3.27E-25 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 2.5E-11 T 13-09-2016 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 2.5E-11 T 13-09-2016 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 241 255 2.5E-11 T 13-09-2016 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 282 289 2.5E-11 T 13-09-2016 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 1.6E-14 T 13-09-2016 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 1.6E-14 T 13-09-2016 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 1.6E-14 T 13-09-2016 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 1.6E-14 T 13-09-2016 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 SUPERFAMILY SSF51905 156 315 2.66E-23 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 14 806 0.0 T 13-09-2016 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 UniPathway: UPA00653 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 PANTHER PTHR11493 9 262 5.6E-273 T 13-09-2016 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 Gene3D G3DSA:3.50.50.60 115 237 2.3E-33 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 PRINTS PR00397 Sirohaem Fe-binding site signature 642 660 9.2E-7 T 13-09-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS19910 ed2237d5ba58732683a5f585ce5ed124 853 PRINTS PR00397 Sirohaem Fe-binding site signature 685 703 9.2E-7 T 13-09-2016 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS20830 3112425845ef635a6e3b790bc2142952 715 Gene3D G3DSA:3.40.50.720 314 501 3.3E-53 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20830 3112425845ef635a6e3b790bc2142952 715 SUPERFAMILY SSF48179 626 712 3.15E-18 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS20830 3112425845ef635a6e3b790bc2142952 715 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 500 599 1.1E-14 T 13-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS20830 3112425845ef635a6e3b790bc2142952 715 Gene3D G3DSA:1.10.1040.10 632 712 1.8E-13 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS20830 3112425845ef635a6e3b790bc2142952 715 SUPERFAMILY SSF51735 319 498 1.32E-52 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20830 3112425845ef635a6e3b790bc2142952 715 Gene3D G3DSA:1.10.1040.10 502 600 6.1E-12 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS20830 3112425845ef635a6e3b790bc2142952 715 SUPERFAMILY SSF52096 2 300 2.58E-58 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20830 3112425845ef635a6e3b790bc2142952 715 Gene3D G3DSA:3.90.226.10 2 201 5.1E-55 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20830 3112425845ef635a6e3b790bc2142952 715 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 319 497 4.5E-58 T 13-09-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS20830 3112425845ef635a6e3b790bc2142952 715 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 196 3.0E-37 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS20830 3112425845ef635a6e3b790bc2142952 715 PANTHER PTHR23309:SF6 4 712 2.1E-277 T 13-09-2016 THL1_RS20830 3112425845ef635a6e3b790bc2142952 715 SUPERFAMILY SSF48179 500 615 1.02E-15 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS20830 3112425845ef635a6e3b790bc2142952 715 PANTHER PTHR23309 4 712 2.1E-277 T 13-09-2016 THL1_RS20220 aa78d634b34072d7a3e895fe420b55aa 568 Gene3D G3DSA:2.30.38.10 381 452 2.2E-29 T 13-09-2016 THL1_RS20220 aa78d634b34072d7a3e895fe420b55aa 568 PANTHER PTHR24096 178 554 1.1E-182 T 13-09-2016 THL1_RS20220 aa78d634b34072d7a3e895fe420b55aa 568 PANTHER PTHR24096 25 161 1.1E-182 T 13-09-2016 THL1_RS20220 aa78d634b34072d7a3e895fe420b55aa 568 ProSitePatterns PS00455 Putative AMP-binding domain signature. 212 223 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS20220 aa78d634b34072d7a3e895fe420b55aa 568 Gene3D G3DSA:3.30.300.30 458 560 6.4E-31 T 13-09-2016 THL1_RS20220 aa78d634b34072d7a3e895fe420b55aa 568 SUPERFAMILY SSF56801 21 558 9.94E-151 T 13-09-2016 THL1_RS20220 aa78d634b34072d7a3e895fe420b55aa 568 Pfam PF13193 AMP-binding enzyme C-terminal domain 470 545 1.1E-18 T 13-09-2016 IPR025110 AMP-binding enzyme C-terminal domain THL1_RS20220 aa78d634b34072d7a3e895fe420b55aa 568 Gene3D G3DSA:3.40.50.980 23 145 1.9E-34 T 13-09-2016 THL1_RS20220 aa78d634b34072d7a3e895fe420b55aa 568 Gene3D G3DSA:3.40.50.980 185 218 1.9E-34 T 13-09-2016 THL1_RS20220 aa78d634b34072d7a3e895fe420b55aa 568 Pfam PF00501 AMP-binding enzyme 31 461 2.2E-110 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS20220 aa78d634b34072d7a3e895fe420b55aa 568 Gene3D G3DSA:3.40.50.980 219 380 2.2E-43 T 13-09-2016 THL1_RS02730 cfe718fe2d51a67b972f7edf3d9bfe4e 279 PANTHER PTHR41711 1 249 1.3E-28 T 13-09-2016 THL1_RS02730 cfe718fe2d51a67b972f7edf3d9bfe4e 279 PANTHER PTHR41711:SF1 1 249 1.3E-28 T 13-09-2016 THL1_RS10030 770949df0fa3dd01a832973bec3668a3 360 SMART SM01329 4 353 5.0E-216 T 13-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 THL1_RS10030 770949df0fa3dd01a832973bec3668a3 360 Gene3D G3DSA:3.40.718.10 2 357 4.0E-136 T 13-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 THL1_RS10030 770949df0fa3dd01a832973bec3668a3 360 SUPERFAMILY SSF53659 1 357 1.76E-127 T 13-09-2016 THL1_RS10030 770949df0fa3dd01a832973bec3668a3 360 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 357 53.783 T 13-09-2016 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396|UniPathway: UPA00048 THL1_RS10030 770949df0fa3dd01a832973bec3668a3 360 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 352 1.9E-164 T 13-09-2016 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396|UniPathway: UPA00048 THL1_RS10030 770949df0fa3dd01a832973bec3668a3 360 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 13-09-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 THL1_RS10030 770949df0fa3dd01a832973bec3668a3 360 PANTHER PTHR11835:SF35 2 360 1.7E-213 T 13-09-2016 THL1_RS10030 770949df0fa3dd01a832973bec3668a3 360 PANTHER PTHR11835 2 360 1.7E-213 T 13-09-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 THL1_RS10030 770949df0fa3dd01a832973bec3668a3 360 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 353 2.0E-142 T 13-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 THL1_RS01655 760edce24339dd65b33ba66f538f42e0 354 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 85 - T 13-09-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 THL1_RS01655 760edce24339dd65b33ba66f538f42e0 354 PANTHER PTHR30304 1 349 3.7E-124 T 13-09-2016 THL1_RS01655 760edce24339dd65b33ba66f538f42e0 354 PIRSF PIRSF001359 1 329 1.1E-82 T 13-09-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 THL1_RS01655 760edce24339dd65b33ba66f538f42e0 354 SUPERFAMILY SSF51569 3 328 6.01E-107 T 13-09-2016 THL1_RS01655 760edce24339dd65b33ba66f538f42e0 354 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 327 9.3E-93 T 13-09-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 THL1_RS01655 760edce24339dd65b33ba66f538f42e0 354 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 329 9.6E-97 T 13-09-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 THL1_RS01655 760edce24339dd65b33ba66f538f42e0 354 Gene3D G3DSA:3.20.20.70 1 335 1.5E-109 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS01655 760edce24339dd65b33ba66f538f42e0 354 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 349 4.7E-213 T 13-09-2016 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|UniPathway: UPA00109 THL1_RS01655 760edce24339dd65b33ba66f538f42e0 354 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 13-09-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 THL1_RS11585 67cbcba0cb62c09e601652b48bd06c49 403 Gene3D G3DSA:3.40.640.10 50 278 1.1E-68 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS11585 67cbcba0cb62c09e601652b48bd06c49 403 PANTHER PTHR11751 8 403 7.9E-194 T 13-09-2016 THL1_RS11585 67cbcba0cb62c09e601652b48bd06c49 403 Gene3D G3DSA:3.90.1150.10 279 402 1.9E-40 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS11585 67cbcba0cb62c09e601652b48bd06c49 403 SUPERFAMILY SSF53383 6 401 6.38E-96 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS11585 67cbcba0cb62c09e601652b48bd06c49 403 PANTHER PTHR11751:SF303 8 403 7.9E-194 T 13-09-2016 THL1_RS11585 67cbcba0cb62c09e601652b48bd06c49 403 Pfam PF00155 Aminotransferase class I and II 35 391 1.7E-48 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS05990 332821f2f613664a9c3b63c94fb18c4d 429 PANTHER PTHR11476 3 429 7.4E-222 T 13-09-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 THL1_RS05990 332821f2f613664a9c3b63c94fb18c4d 429 PANTHER PTHR11476:SF9 3 429 7.4E-222 T 13-09-2016 THL1_RS05990 332821f2f613664a9c3b63c94fb18c4d 429 Gene3D G3DSA:3.40.50.800 330 424 3.7E-30 T 13-09-2016 IPR004154 Anticodon-binding THL1_RS05990 332821f2f613664a9c3b63c94fb18c4d 429 SUPERFAMILY SSF52954 329 425 8.34E-23 T 13-09-2016 IPR004154 Anticodon-binding THL1_RS05990 332821f2f613664a9c3b63c94fb18c4d 429 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 412 1.5E-151 T 13-09-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 THL1_RS05990 332821f2f613664a9c3b63c94fb18c4d 429 Gene3D G3DSA:3.30.930.10 4 186 4.3E-96 T 13-09-2016 THL1_RS05990 332821f2f613664a9c3b63c94fb18c4d 429 Gene3D G3DSA:3.30.930.10 222 325 4.3E-96 T 13-09-2016 THL1_RS05990 332821f2f613664a9c3b63c94fb18c4d 429 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 424 33.436 T 13-09-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 THL1_RS05990 332821f2f613664a9c3b63c94fb18c4d 429 PIRSF PIRSF001549 2 425 3.2E-116 T 13-09-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 THL1_RS05990 332821f2f613664a9c3b63c94fb18c4d 429 Pfam PF03129 Anticodon binding domain 335 422 4.2E-9 T 13-09-2016 IPR004154 Anticodon-binding THL1_RS05990 332821f2f613664a9c3b63c94fb18c4d 429 Pfam PF13393 Histidyl-tRNA synthetase 10 313 2.1E-46 T 13-09-2016 THL1_RS05990 332821f2f613664a9c3b63c94fb18c4d 429 SUPERFAMILY SSF55681 6 321 1.73E-103 T 13-09-2016 THL1_RS06795 85483fd8333d8319f654797cf044180d 306 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 4 297 1.8E-82 T 13-09-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 THL1_RS06795 85483fd8333d8319f654797cf044180d 306 PANTHER PTHR30606 1 306 2.8E-169 T 13-09-2016 THL1_RS06795 85483fd8333d8319f654797cf044180d 306 PANTHER PTHR30606:SF5 1 306 2.8E-169 T 13-09-2016 THL1_RS06795 85483fd8333d8319f654797cf044180d 306 Hamap MF_01942 Lipid A biosynthesis lauroyltransferase [lpxL]. 3 306 48.978 T 13-09-2016 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24|UniPathway: UPA00030 THL1_RS06795 85483fd8333d8319f654797cf044180d 306 TIGRFAM TIGR02207 lipid_A_htrB: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase 4 306 2.0E-131 T 13-09-2016 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 KEGG: 00600+2.3.1.24|UniPathway: UPA00030 THL1_RS06795 85483fd8333d8319f654797cf044180d 306 PIRSF PIRSF026649 1 306 9.0E-102 T 13-09-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 THL1_RS23195 227586a91fb0d8b9518e46bdc4e50a97 132 SUPERFAMILY SSF54427 1 128 1.87E-28 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS23195 227586a91fb0d8b9518e46bdc4e50a97 132 TIGRFAM TIGR02096 TIGR02096: conserved hypothetical protein 4 131 3.3E-43 T 13-09-2016 IPR011721 Conserved hypothetical protein CHP02096 THL1_RS23195 227586a91fb0d8b9518e46bdc4e50a97 132 Pfam PF12680 SnoaL-like domain 7 118 8.7E-18 T 13-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain THL1_RS23195 227586a91fb0d8b9518e46bdc4e50a97 132 Gene3D G3DSA:3.10.450.50 1 131 1.9E-27 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS26965 c0a2877880eb77a0645f009c28075a67 354 PANTHER PTHR10366 2 353 4.7E-178 T 13-09-2016 THL1_RS26965 c0a2877880eb77a0645f009c28075a67 354 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 339 1.0E-153 T 13-09-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 THL1_RS26965 c0a2877880eb77a0645f009c28075a67 354 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 326 1.8E-97 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS26965 c0a2877880eb77a0645f009c28075a67 354 Gene3D G3DSA:3.40.50.720 1 191 2.3E-66 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS26965 c0a2877880eb77a0645f009c28075a67 354 SUPERFAMILY SSF51735 1 346 5.14E-95 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS26965 c0a2877880eb77a0645f009c28075a67 354 PANTHER PTHR10366:SF41 2 353 4.7E-178 T 13-09-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 THL1_RS26965 c0a2877880eb77a0645f009c28075a67 354 Gene3D G3DSA:3.90.25.10 192 343 2.1E-55 T 13-09-2016 THL1_RS17450 84486f694312255fbd555bbfcff6807d 292 PANTHER PTHR23309 3 280 2.6E-86 T 13-09-2016 THL1_RS17450 84486f694312255fbd555bbfcff6807d 292 PANTHER PTHR23309:SF9 3 280 2.6E-86 T 13-09-2016 THL1_RS17450 84486f694312255fbd555bbfcff6807d 292 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 92 112 - T 13-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THL1_RS17450 84486f694312255fbd555bbfcff6807d 292 Gene3D G3DSA:3.90.226.10 4 278 4.9E-58 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS17450 84486f694312255fbd555bbfcff6807d 292 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 189 7.7E-35 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS17450 84486f694312255fbd555bbfcff6807d 292 SUPERFAMILY SSF52096 4 280 6.74E-62 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS24805 d2bbbdab942c080d3df9e25f6598949a 521 SUPERFAMILY SSF53822 164 508 1.88E-43 T 13-09-2016 IPR028082 Periplasmic binding protein-like I THL1_RS24805 d2bbbdab942c080d3df9e25f6598949a 521 Gene3D G3DSA:3.40.50.2300 424 490 1.8E-26 T 13-09-2016 THL1_RS24805 d2bbbdab942c080d3df9e25f6598949a 521 Gene3D G3DSA:3.40.50.2300 159 285 1.8E-26 T 13-09-2016 THL1_RS24805 d2bbbdab942c080d3df9e25f6598949a 521 Gene3D G3DSA:1.10.760.10 60 155 8.6E-8 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS24805 d2bbbdab942c080d3df9e25f6598949a 521 PANTHER PTHR30483:SF11 103 512 1.2E-30 T 13-09-2016 THL1_RS24805 d2bbbdab942c080d3df9e25f6598949a 521 PANTHER PTHR30483 103 512 1.2E-30 T 13-09-2016 THL1_RS24805 d2bbbdab942c080d3df9e25f6598949a 521 Pfam PF13458 Periplasmic binding protein 164 506 1.1E-43 T 13-09-2016 IPR028081 Leucine-binding protein domain THL1_RS24805 d2bbbdab942c080d3df9e25f6598949a 521 SUPERFAMILY SSF46626 3 160 1.34E-12 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS24805 d2bbbdab942c080d3df9e25f6598949a 521 Pfam PF00034 Cytochrome c 63 151 2.1E-5 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS04360 edea36c284d9bf8f8970fd4db1707aac 223 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 62 - T 13-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site THL1_RS04360 edea36c284d9bf8f8970fd4db1707aac 223 SUPERFAMILY SSF46689 9 92 4.79E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS04360 edea36c284d9bf8f8970fd4db1707aac 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.5E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS04360 edea36c284d9bf8f8970fd4db1707aac 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.5E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS04360 edea36c284d9bf8f8970fd4db1707aac 223 SUPERFAMILY SSF48498 88 208 1.05E-8 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS04360 edea36c284d9bf8f8970fd4db1707aac 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 7.6E-12 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS04360 edea36c284d9bf8f8970fd4db1707aac 223 PANTHER PTHR30055 4 171 5.0E-24 T 13-09-2016 THL1_RS04360 edea36c284d9bf8f8970fd4db1707aac 223 Gene3D G3DSA:1.10.357.10 11 207 6.2E-31 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS26250 0dc7d9188930537950c7ee0f957dd01b 144 PANTHER PTHR10438:SF266 28 139 9.4E-30 T 13-09-2016 THL1_RS26250 0dc7d9188930537950c7ee0f957dd01b 144 PANTHER PTHR10438 28 139 9.4E-30 T 13-09-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THL1_RS26250 0dc7d9188930537950c7ee0f957dd01b 144 Pfam PF00085 Thioredoxin 44 140 1.4E-24 T 13-09-2016 IPR013766 Thioredoxin domain GO:0045454 THL1_RS26250 0dc7d9188930537950c7ee0f957dd01b 144 Gene3D G3DSA:3.40.30.10 43 140 4.4E-29 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS26250 0dc7d9188930537950c7ee0f957dd01b 144 SUPERFAMILY SSF52833 29 140 2.5E-33 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS26250 0dc7d9188930537950c7ee0f957dd01b 144 ProSitePatterns PS00194 Thioredoxin family active site. 60 78 - T 13-09-2016 IPR017937 Thioredoxin, conserved site GO:0045454 THL1_RS26250 0dc7d9188930537950c7ee0f957dd01b 144 PRINTS PR00421 Thioredoxin family signature 107 118 3.6E-8 T 13-09-2016 THL1_RS26250 0dc7d9188930537950c7ee0f957dd01b 144 PRINTS PR00421 Thioredoxin family signature 59 67 3.6E-8 T 13-09-2016 THL1_RS26250 0dc7d9188930537950c7ee0f957dd01b 144 PRINTS PR00421 Thioredoxin family signature 67 76 3.6E-8 T 13-09-2016 THL1_RS07055 48c5a910e258825ebe363595d08fa799 291 PANTHER PTHR11941 1 79 2.4E-78 T 13-09-2016 THL1_RS07055 48c5a910e258825ebe363595d08fa799 291 PANTHER PTHR11941 98 254 2.4E-78 T 13-09-2016 THL1_RS07055 48c5a910e258825ebe363595d08fa799 291 PANTHER PTHR11941:SF85 98 254 2.4E-78 T 13-09-2016 THL1_RS07055 48c5a910e258825ebe363595d08fa799 291 Pfam PF00378 Enoyl-CoA hydratase/isomerase 20 253 9.2E-40 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS07055 48c5a910e258825ebe363595d08fa799 291 Gene3D G3DSA:3.90.226.10 3 251 1.5E-64 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS07055 48c5a910e258825ebe363595d08fa799 291 SUPERFAMILY SSF52096 9 268 5.41E-65 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS07055 48c5a910e258825ebe363595d08fa799 291 PANTHER PTHR11941:SF85 1 79 2.4E-78 T 13-09-2016 THL1_RS06555 427dd29987b36ccda128d6be00334778 357 SUPERFAMILY SSF51658 90 276 1.2E-17 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS06555 427dd29987b36ccda128d6be00334778 357 Pfam PF01261 Xylose isomerase-like TIM barrel 68 233 9.4E-11 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS06555 427dd29987b36ccda128d6be00334778 357 Gene3D G3DSA:3.20.20.150 54 241 4.9E-23 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS04220 a5d66c8bd030969a2e11587246eca2a9 117 Pfam PF02410 Ribosomal silencing factor during starvation 11 104 7.2E-27 T 13-09-2016 THL1_RS04220 a5d66c8bd030969a2e11587246eca2a9 117 Gene3D G3DSA:3.30.460.10 2 107 1.2E-38 T 13-09-2016 THL1_RS04220 a5d66c8bd030969a2e11587246eca2a9 117 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 24.726 T 13-09-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS THL1_RS04220 a5d66c8bd030969a2e11587246eca2a9 117 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 7 104 3.7E-37 T 13-09-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS THL1_RS04220 a5d66c8bd030969a2e11587246eca2a9 117 PANTHER PTHR21043 1 107 5.7E-43 T 13-09-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS THL1_RS04220 a5d66c8bd030969a2e11587246eca2a9 117 SUPERFAMILY SSF81301 1 110 9.65E-39 T 13-09-2016 THL1_RS07085 22042fd8a45c49b8cc9f51f019e1dc20 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.3E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07085 22042fd8a45c49b8cc9f51f019e1dc20 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.3E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07085 22042fd8a45c49b8cc9f51f019e1dc20 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.3E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07085 22042fd8a45c49b8cc9f51f019e1dc20 291 Gene3D G3DSA:3.40.50.720 5 249 2.7E-71 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07085 22042fd8a45c49b8cc9f51f019e1dc20 291 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 200 1.6E-4 T 13-09-2016 THL1_RS07085 22042fd8a45c49b8cc9f51f019e1dc20 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.8E-19 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07085 22042fd8a45c49b8cc9f51f019e1dc20 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.8E-19 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07085 22042fd8a45c49b8cc9f51f019e1dc20 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 2.8E-19 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07085 22042fd8a45c49b8cc9f51f019e1dc20 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.8E-19 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07085 22042fd8a45c49b8cc9f51f019e1dc20 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.8E-19 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07085 22042fd8a45c49b8cc9f51f019e1dc20 291 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS07085 22042fd8a45c49b8cc9f51f019e1dc20 291 SUPERFAMILY SSF51735 5 248 7.85E-64 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07085 22042fd8a45c49b8cc9f51f019e1dc20 291 Pfam PF00106 short chain dehydrogenase 8 201 9.9E-46 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07085 22042fd8a45c49b8cc9f51f019e1dc20 291 PANTHER PTHR24322:SF428 161 192 3.6E-42 T 13-09-2016 THL1_RS07085 22042fd8a45c49b8cc9f51f019e1dc20 291 PANTHER PTHR24322:SF428 11 135 3.6E-42 T 13-09-2016 THL1_RS07085 22042fd8a45c49b8cc9f51f019e1dc20 291 PANTHER PTHR24322 161 192 3.6E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS07085 22042fd8a45c49b8cc9f51f019e1dc20 291 PANTHER PTHR24322 11 135 3.6E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20670 aa8d573aa478cffdd72148db4e5f8bf4 212 PANTHER PTHR30055:SF92 6 124 3.7E-18 T 13-09-2016 THL1_RS20670 aa8d573aa478cffdd72148db4e5f8bf4 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 66 4.6E-16 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20670 aa8d573aa478cffdd72148db4e5f8bf4 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 7.0E-9 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20670 aa8d573aa478cffdd72148db4e5f8bf4 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 7.0E-9 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20670 aa8d573aa478cffdd72148db4e5f8bf4 212 SUPERFAMILY SSF46689 9 78 3.74E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS20670 aa8d573aa478cffdd72148db4e5f8bf4 212 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 65 - T 13-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site THL1_RS20670 aa8d573aa478cffdd72148db4e5f8bf4 212 PANTHER PTHR30055 6 124 3.7E-18 T 13-09-2016 THL1_RS20670 aa8d573aa478cffdd72148db4e5f8bf4 212 Gene3D G3DSA:1.10.357.10 8 207 3.2E-25 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS11745 fdf718fcb62298086ba2bfafc7827b2f 176 Gene3D G3DSA:3.90.1140.10 7 171 4.6E-42 T 13-09-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase THL1_RS11745 fdf718fcb62298086ba2bfafc7827b2f 176 SUPERFAMILY SSF55144 7 171 3.66E-37 T 13-09-2016 IPR009097 RNA ligase/cyclic nucleotide phosphodiesterase THL1_RS11745 fdf718fcb62298086ba2bfafc7827b2f 176 PANTHER PTHR35561:SF1 6 172 1.2E-36 T 13-09-2016 THL1_RS11745 fdf718fcb62298086ba2bfafc7827b2f 176 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 7 170 6.2E-31 T 13-09-2016 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 THL1_RS11745 fdf718fcb62298086ba2bfafc7827b2f 176 PANTHER PTHR35561 6 172 1.2E-36 T 13-09-2016 THL1_RS11745 fdf718fcb62298086ba2bfafc7827b2f 176 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 6 170 19.226 T 13-09-2016 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 THL1_RS11745 fdf718fcb62298086ba2bfafc7827b2f 176 Pfam PF13563 2'-5' RNA ligase superfamily 23 135 5.4E-13 T 13-09-2016 THL1_RS09665 6a586c499ae1515499bf90f0fa4278be 189 SUPERFAMILY SSF46689 2 76 5.64E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS09665 6a586c499ae1515499bf90f0fa4278be 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 8.2E-5 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS09665 6a586c499ae1515499bf90f0fa4278be 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 8.2E-5 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS09665 6a586c499ae1515499bf90f0fa4278be 189 SUPERFAMILY SSF48498 80 177 7.41E-20 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS09665 6a586c499ae1515499bf90f0fa4278be 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 3.6E-10 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS09665 6a586c499ae1515499bf90f0fa4278be 189 PANTHER PTHR30328:SF18 1 178 9.8E-42 T 13-09-2016 THL1_RS09665 6a586c499ae1515499bf90f0fa4278be 189 Gene3D G3DSA:1.10.357.10 59 177 3.3E-32 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS09665 6a586c499ae1515499bf90f0fa4278be 189 PANTHER PTHR30328 1 178 9.8E-42 T 13-09-2016 THL1_RS09665 6a586c499ae1515499bf90f0fa4278be 189 Gene3D G3DSA:1.10.10.60 2 58 1.3E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS09870 1038ad7e7a237cca27080ce84cf9f2f8 106 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 40 104 1.7E-23 T 13-09-2016 IPR004509 Competence protein ComEA, helix-hairpin-helix domain THL1_RS09870 1038ad7e7a237cca27080ce84cf9f2f8 106 Gene3D G3DSA:1.10.150.320 31 105 2.2E-19 T 13-09-2016 THL1_RS09870 1038ad7e7a237cca27080ce84cf9f2f8 106 Pfam PF12836 Helix-hairpin-helix motif 41 103 3.5E-21 T 13-09-2016 THL1_RS09870 1038ad7e7a237cca27080ce84cf9f2f8 106 PANTHER PTHR21180 40 105 8.7E-20 T 13-09-2016 THL1_RS09870 1038ad7e7a237cca27080ce84cf9f2f8 106 SUPERFAMILY SSF47781 32 104 5.11E-26 T 13-09-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.3E-13 T 13-09-2016 THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 1.3E-13 T 13-09-2016 THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.3E-13 T 13-09-2016 THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 PANTHER PTHR11922:SF7 1 195 4.4E-98 T 13-09-2016 THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 SUPERFAMILY SSF52317 2 193 1.65E-56 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 Pfam PF00117 Glutamine amidotransferase class-I 4 191 5.8E-56 T 13-09-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 6.5E-7 T 13-09-2016 THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 91 108 6.5E-7 T 13-09-2016 THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 6.5E-7 T 13-09-2016 THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 PANTHER PTHR11922 1 195 4.4E-98 T 13-09-2016 THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 Gene3D G3DSA:3.40.50.880 2 193 1.6E-68 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 PRINTS PR00097 Anthranilate synthase component II signature 119 131 4.1E-36 T 13-09-2016 THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 PRINTS PR00097 Anthranilate synthase component II signature 47 56 4.1E-36 T 13-09-2016 THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 PRINTS PR00097 Anthranilate synthase component II signature 169 182 4.1E-36 T 13-09-2016 THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 PRINTS PR00097 Anthranilate synthase component II signature 99 107 4.1E-36 T 13-09-2016 THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 PRINTS PR00097 Anthranilate synthase component II signature 2 16 4.1E-36 T 13-09-2016 THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 PRINTS PR00097 Anthranilate synthase component II signature 74 85 4.1E-36 T 13-09-2016 THL1_RS03305 79c36a23e65092d036b39f572dd55d78 197 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 191 1.8E-87 T 13-09-2016 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 THL1_RS27135 fd2ac7fc6e5fe9d80f6041c94b0982da 437 Pfam PF00672 HAMP domain 150 216 2.2E-12 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS27135 fd2ac7fc6e5fe9d80f6041c94b0982da 437 Gene3D G3DSA:3.30.565.10 283 430 3.7E-35 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS27135 fd2ac7fc6e5fe9d80f6041c94b0982da 437 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 323 428 2.6E-17 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS27135 fd2ac7fc6e5fe9d80f6041c94b0982da 437 Pfam PF00512 His Kinase A (phospho-acceptor) domain 223 276 9.2E-10 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS27135 fd2ac7fc6e5fe9d80f6041c94b0982da 437 SUPERFAMILY SSF55874 280 429 9.04E-34 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS27135 fd2ac7fc6e5fe9d80f6041c94b0982da 437 SMART SM00304 168 220 1.4E-6 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS27135 fd2ac7fc6e5fe9d80f6041c94b0982da 437 SUPERFAMILY SSF47384 205 277 1.08E-13 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS27135 fd2ac7fc6e5fe9d80f6041c94b0982da 437 PANTHER PTHR24423 162 428 5.1E-61 T 13-09-2016 THL1_RS27135 fd2ac7fc6e5fe9d80f6041c94b0982da 437 PANTHER PTHR24423 1 7 5.1E-61 T 13-09-2016 THL1_RS27135 fd2ac7fc6e5fe9d80f6041c94b0982da 437 SMART SM00387 318 430 1.5E-26 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS27135 fd2ac7fc6e5fe9d80f6041c94b0982da 437 Gene3D G3DSA:1.10.287.130 211 275 1.2E-15 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS27135 fd2ac7fc6e5fe9d80f6041c94b0982da 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 371 4.7E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS27135 fd2ac7fc6e5fe9d80f6041c94b0982da 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 408 4.7E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS27135 fd2ac7fc6e5fe9d80f6041c94b0982da 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 385 4.7E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS27135 fd2ac7fc6e5fe9d80f6041c94b0982da 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 427 4.7E-14 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS27135 fd2ac7fc6e5fe9d80f6041c94b0982da 437 SMART SM00388 221 280 7.8E-10 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS01400 ce3cd9f9bdd3bcd4ddd0579235073d35 44 Pfam PF04076 Bacterial OB fold (BOF) protein 1 41 5.0E-11 T 13-09-2016 IPR005220 Bacterial OB-fold THL1_RS01400 ce3cd9f9bdd3bcd4ddd0579235073d35 44 Gene3D G3DSA:2.40.50.200 1 43 3.3E-10 T 13-09-2016 IPR005220 Bacterial OB-fold THL1_RS01400 ce3cd9f9bdd3bcd4ddd0579235073d35 44 PANTHER PTHR36571:SF1 1 44 5.1E-12 T 13-09-2016 THL1_RS01400 ce3cd9f9bdd3bcd4ddd0579235073d35 44 PANTHER PTHR36571 1 44 5.1E-12 T 13-09-2016 THL1_RS01400 ce3cd9f9bdd3bcd4ddd0579235073d35 44 SUPERFAMILY SSF101756 1 42 6.93E-10 T 13-09-2016 IPR005220 Bacterial OB-fold THL1_RS09585 56baf21cfa0cdbd9b7cda23ccefab3a8 459 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 18 64 1.3E-11 T 13-09-2016 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal THL1_RS25840 e81777fa0a645a626189832e3635d318 61 PANTHER PTHR38602 1 61 2.4E-15 T 13-09-2016 THL1_RS25840 e81777fa0a645a626189832e3635d318 61 Pfam PF09838 Uncharacterized protein conserved in bacteria (DUF2065) 6 60 1.4E-21 T 13-09-2016 IPR019201 Protein of unknown function DUF2065 THL1_RS25840 e81777fa0a645a626189832e3635d318 61 PANTHER PTHR38602:SF1 1 61 2.4E-15 T 13-09-2016 THL1_RS28050 0c0a923460b8301545b7b7f954ca6e6f 429 PANTHER PTHR23508 6 424 2.3E-250 T 13-09-2016 THL1_RS28050 0c0a923460b8301545b7b7f954ca6e6f 429 PANTHER PTHR23508:SF5 6 424 2.3E-250 T 13-09-2016 THL1_RS28050 0c0a923460b8301545b7b7f954ca6e6f 429 Gene3D G3DSA:1.20.1250.20 249 425 7.7E-15 T 13-09-2016 THL1_RS28050 0c0a923460b8301545b7b7f954ca6e6f 429 Gene3D G3DSA:1.20.1250.20 24 229 5.5E-20 T 13-09-2016 THL1_RS28050 0c0a923460b8301545b7b7f954ca6e6f 429 SUPERFAMILY SSF103473 9 428 1.7E-60 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS28050 0c0a923460b8301545b7b7f954ca6e6f 429 Pfam PF07690 Major Facilitator Superfamily 68 389 3.3E-23 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS04635 6626d3d71fe939cb78201bf8a24c9973 179 PANTHER PTHR11908:SF66 2 159 4.1E-22 T 13-09-2016 THL1_RS04635 6626d3d71fe939cb78201bf8a24c9973 179 Gene3D G3DSA:3.10.20.30 3 83 5.9E-19 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS04635 6626d3d71fe939cb78201bf8a24c9973 179 SUPERFAMILY SSF54292 6 87 6.74E-16 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS04635 6626d3d71fe939cb78201bf8a24c9973 179 Pfam PF01799 [2Fe-2S] binding domain 82 166 6.5E-21 T 13-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 THL1_RS04635 6626d3d71fe939cb78201bf8a24c9973 179 SUPERFAMILY SSF47741 97 171 1.96E-20 T 13-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 THL1_RS04635 6626d3d71fe939cb78201bf8a24c9973 179 Gene3D G3DSA:1.10.150.120 84 171 1.3E-23 T 13-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 THL1_RS04635 6626d3d71fe939cb78201bf8a24c9973 179 PANTHER PTHR11908 2 159 4.1E-22 T 13-09-2016 THL1_RS22820 6fa616346c7db55cb07f04dd6ddd8816 215 SUPERFAMILY SSF52540 1 190 1.09E-44 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22820 6fa616346c7db55cb07f04dd6ddd8816 215 PANTHER PTHR23359 1 215 1.8E-109 T 13-09-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 THL1_RS22820 6fa616346c7db55cb07f04dd6ddd8816 215 Pfam PF00406 Adenylate kinase 5 185 1.5E-57 T 13-09-2016 THL1_RS22820 6fa616346c7db55cb07f04dd6ddd8816 215 Hamap MF_00235 Adenylate kinase [adk]. 1 215 53.066 T 13-09-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 THL1_RS22820 6fa616346c7db55cb07f04dd6ddd8816 215 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 13-09-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 THL1_RS22820 6fa616346c7db55cb07f04dd6ddd8816 215 PRINTS PR00094 Adenylate kinase signature 81 97 2.4E-36 T 13-09-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 THL1_RS22820 6fa616346c7db55cb07f04dd6ddd8816 215 PRINTS PR00094 Adenylate kinase signature 156 171 2.4E-36 T 13-09-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 THL1_RS22820 6fa616346c7db55cb07f04dd6ddd8816 215 PRINTS PR00094 Adenylate kinase signature 32 46 2.4E-36 T 13-09-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 THL1_RS22820 6fa616346c7db55cb07f04dd6ddd8816 215 PRINTS PR00094 Adenylate kinase signature 4 17 2.4E-36 T 13-09-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 THL1_RS22820 6fa616346c7db55cb07f04dd6ddd8816 215 PRINTS PR00094 Adenylate kinase signature 173 187 2.4E-36 T 13-09-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 THL1_RS22820 6fa616346c7db55cb07f04dd6ddd8816 215 Gene3D G3DSA:3.40.50.300 1 213 3.2E-79 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22820 6fa616346c7db55cb07f04dd6ddd8816 215 TIGRFAM TIGR01351 adk: adenylate kinase 2 213 1.1E-75 T 13-09-2016 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 THL1_RS22820 6fa616346c7db55cb07f04dd6ddd8816 215 Pfam PF05191 Adenylate kinase, active site lid 123 158 1.7E-16 T 13-09-2016 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 SUPERFAMILY SSF55909 5 414 5.4E-139 T 13-09-2016 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 Gene3D G3DSA:3.75.10.10 155 415 7.5E-131 T 13-09-2016 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 Gene3D G3DSA:3.75.10.10 2 69 7.5E-131 T 13-09-2016 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 PANTHER PTHR12737 320 416 3.4E-130 T 13-09-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 PANTHER PTHR12737 1 93 3.4E-130 T 13-09-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 Pfam PF02274 Amidinotransferase 20 411 2.7E-100 T 13-09-2016 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 Hamap MF_00242 Arginine deiminase [arcA]. 3 414 48.16 T 13-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 PIRSF PIRSF006356 1 414 1.2E-145 T 13-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 PANTHER PTHR12737:SF13 1 93 3.4E-130 T 13-09-2016 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 PANTHER PTHR12737:SF13 155 297 3.4E-130 T 13-09-2016 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 PANTHER PTHR12737:SF13 320 416 3.4E-130 T 13-09-2016 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 PANTHER PTHR12737 155 297 3.4E-130 T 13-09-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 TIGRFAM TIGR01078 arcA: arginine deiminase 8 414 3.0E-168 T 13-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 PRINTS PR01466 Bacterial arginine deiminase signature 4 24 8.3E-51 T 13-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 PRINTS PR01466 Bacterial arginine deiminase signature 155 173 8.3E-51 T 13-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 PRINTS PR01466 Bacterial arginine deiminase signature 393 411 8.3E-51 T 13-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 PRINTS PR01466 Bacterial arginine deiminase signature 350 367 8.3E-51 T 13-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 PRINTS PR01466 Bacterial arginine deiminase signature 370 384 8.3E-51 T 13-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 THL1_RS27005 a16da7b48ee495bd0037d3b062ccf51b 416 PRINTS PR01466 Bacterial arginine deiminase signature 183 198 8.3E-51 T 13-09-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 THL1_RS11305 045014c48da5c3015ce3fb58e18e07df 336 SUPERFAMILY SSF50331 236 332 4.93E-10 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS11305 045014c48da5c3015ce3fb58e18e07df 336 SMART SM00382 29 212 8.7E-19 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS11305 045014c48da5c3015ce3fb58e18e07df 336 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS11305 045014c48da5c3015ce3fb58e18e07df 336 Pfam PF00005 ABC transporter 21 162 1.0E-31 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS11305 045014c48da5c3015ce3fb58e18e07df 336 Pfam PF08402 TOBE domain 257 334 4.6E-18 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS11305 045014c48da5c3015ce3fb58e18e07df 336 SUPERFAMILY SSF52540 5 244 7.18E-85 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11305 045014c48da5c3015ce3fb58e18e07df 336 PANTHER PTHR24220:SF150 6 248 2.7E-135 T 13-09-2016 THL1_RS11305 045014c48da5c3015ce3fb58e18e07df 336 PANTHER PTHR24220 6 248 2.7E-135 T 13-09-2016 THL1_RS11305 045014c48da5c3015ce3fb58e18e07df 336 Gene3D G3DSA:3.40.50.300 2 234 2.5E-77 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15865 7da1b7f6650018527d4ed56eea463229 577 Gene3D G3DSA:1.20.1560.10 23 339 5.3E-68 T 13-09-2016 THL1_RS15865 7da1b7f6650018527d4ed56eea463229 577 Pfam PF00005 ABC transporter 370 518 2.5E-30 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS15865 7da1b7f6650018527d4ed56eea463229 577 SUPERFAMILY SSF90123 23 335 1.57E-68 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS15865 7da1b7f6650018527d4ed56eea463229 577 SUPERFAMILY SSF52540 344 566 1.58E-70 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15865 7da1b7f6650018527d4ed56eea463229 577 Gene3D G3DSA:3.40.50.300 352 566 1.1E-64 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15865 7da1b7f6650018527d4ed56eea463229 577 ProSitePatterns PS00211 ABC transporters family signature. 490 504 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS15865 7da1b7f6650018527d4ed56eea463229 577 PANTHER PTHR24221 10 565 7.5E-164 T 13-09-2016 THL1_RS15865 7da1b7f6650018527d4ed56eea463229 577 SMART SM00382 378 566 1.4E-13 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS15865 7da1b7f6650018527d4ed56eea463229 577 Pfam PF00664 ABC transporter transmembrane region 37 305 2.2E-40 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS19975 7a666ab4acc917c26e8feaf965e11f2b 415 SUPERFAMILY SSF103473 16 401 6.15E-67 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS19975 7a666ab4acc917c26e8feaf965e11f2b 415 PANTHER PTHR23501:SF11 14 403 1.5E-201 T 13-09-2016 THL1_RS19975 7a666ab4acc917c26e8feaf965e11f2b 415 Gene3D G3DSA:1.20.1250.20 230 399 3.1E-17 T 13-09-2016 THL1_RS19975 7a666ab4acc917c26e8feaf965e11f2b 415 Gene3D G3DSA:1.20.1250.20 24 205 1.1E-32 T 13-09-2016 THL1_RS19975 7a666ab4acc917c26e8feaf965e11f2b 415 ProSitePatterns PS00216 Sugar transport proteins signature 1. 79 95 - T 13-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 THL1_RS19975 7a666ab4acc917c26e8feaf965e11f2b 415 PANTHER PTHR23501 14 403 1.5E-201 T 13-09-2016 THL1_RS19975 7a666ab4acc917c26e8feaf965e11f2b 415 Pfam PF07690 Major Facilitator Superfamily 29 365 2.9E-42 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS18075 c8d534a08d984a0fd63e40590a9a2031 404 PANTHER PTHR30024 1 394 8.1E-163 T 13-09-2016 THL1_RS18075 c8d534a08d984a0fd63e40590a9a2031 404 PANTHER PTHR30024:SF7 1 394 8.1E-163 T 13-09-2016 THL1_RS18075 c8d534a08d984a0fd63e40590a9a2031 404 SUPERFAMILY SSF53850 26 257 5.87E-26 T 13-09-2016 THL1_RS18075 c8d534a08d984a0fd63e40590a9a2031 404 Pfam PF13379 NMT1-like family 20 270 1.4E-95 T 13-09-2016 THL1_RS18075 c8d534a08d984a0fd63e40590a9a2031 404 Gene3D G3DSA:3.40.190.10 148 245 2.1E-7 T 13-09-2016 THL1_RS21450 38b61d4cf30fff3fbf0b057d9e4e433b 718 Gene3D G3DSA:3.40.50.300 483 709 9.6E-72 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21450 38b61d4cf30fff3fbf0b057d9e4e433b 718 SMART SM00382 510 696 4.3E-20 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS21450 38b61d4cf30fff3fbf0b057d9e4e433b 718 SUPERFAMILY SSF90123 157 467 1.44E-48 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS21450 38b61d4cf30fff3fbf0b057d9e4e433b 718 PANTHER PTHR24221:SF248 140 708 3.3E-218 T 13-09-2016 THL1_RS21450 38b61d4cf30fff3fbf0b057d9e4e433b 718 PANTHER PTHR24221:SF248 41 81 3.3E-218 T 13-09-2016 THL1_RS21450 38b61d4cf30fff3fbf0b057d9e4e433b 718 Gene3D G3DSA:3.90.70.10 18 141 1.5E-38 T 13-09-2016 THL1_RS21450 38b61d4cf30fff3fbf0b057d9e4e433b 718 PANTHER PTHR24221 140 708 3.3E-218 T 13-09-2016 THL1_RS21450 38b61d4cf30fff3fbf0b057d9e4e433b 718 PANTHER PTHR24221 41 81 3.3E-218 T 13-09-2016 THL1_RS21450 38b61d4cf30fff3fbf0b057d9e4e433b 718 Pfam PF00005 ABC transporter 501 650 9.1E-34 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS21450 38b61d4cf30fff3fbf0b057d9e4e433b 718 TIGRFAM TIGR03375 type_I_sec_LssB: type I secretion system ATPase 20 714 3.0E-288 T 13-09-2016 IPR017750 ATPase, type I secretion system THL1_RS21450 38b61d4cf30fff3fbf0b057d9e4e433b 718 SUPERFAMILY SSF52540 475 708 1.15E-73 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS21450 38b61d4cf30fff3fbf0b057d9e4e433b 718 Pfam PF00664 ABC transporter transmembrane region 174 430 2.5E-16 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS21450 38b61d4cf30fff3fbf0b057d9e4e433b 718 Gene3D G3DSA:1.20.1560.10 157 467 2.7E-47 T 13-09-2016 THL1_RS03370 fa25db8fdd4819de2c73a0f0fbde89af 344 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 344 1.3E-131 T 13-09-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS03370 fa25db8fdd4819de2c73a0f0fbde89af 344 SUPERFAMILY SSF55347 150 312 1.83E-50 T 13-09-2016 THL1_RS03370 fa25db8fdd4819de2c73a0f0fbde89af 344 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 141 3.2E-38 T 13-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THL1_RS03370 fa25db8fdd4819de2c73a0f0fbde89af 344 Gene3D G3DSA:3.40.50.720 1 158 8.8E-65 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS03370 fa25db8fdd4819de2c73a0f0fbde89af 344 PANTHER PTHR32338:SF8 1 344 1.2E-181 T 13-09-2016 THL1_RS03370 fa25db8fdd4819de2c73a0f0fbde89af 344 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 338 42.998 T 13-09-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS03370 fa25db8fdd4819de2c73a0f0fbde89af 344 Gene3D G3DSA:3.30.360.10 159 312 2.0E-59 T 13-09-2016 THL1_RS03370 fa25db8fdd4819de2c73a0f0fbde89af 344 PANTHER PTHR32338 1 344 1.2E-181 T 13-09-2016 THL1_RS03370 fa25db8fdd4819de2c73a0f0fbde89af 344 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 145 161 - T 13-09-2016 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS03370 fa25db8fdd4819de2c73a0f0fbde89af 344 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 161 315 1.4E-15 T 13-09-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS03370 fa25db8fdd4819de2c73a0f0fbde89af 344 SUPERFAMILY SSF51735 2 174 5.93E-54 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS03370 fa25db8fdd4819de2c73a0f0fbde89af 344 SMART SM00859 3 142 2.2E-64 T 13-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THL1_RS26840 f9344d444812241c184302dc6db1246b 231 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 117 6.5E-20 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS26840 f9344d444812241c184302dc6db1246b 231 Gene3D G3DSA:1.10.3720.10 11 222 8.3E-44 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS26840 f9344d444812241c184302dc6db1246b 231 SUPERFAMILY SSF161098 10 208 4.19E-39 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS26840 f9344d444812241c184302dc6db1246b 231 PANTHER PTHR30133 4 231 2.2E-106 T 13-09-2016 THL1_RS26840 f9344d444812241c184302dc6db1246b 231 PANTHER PTHR30133:SF2 4 231 2.2E-106 T 13-09-2016 THL1_RS26840 f9344d444812241c184302dc6db1246b 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 222 5.8E-20 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01535 b77e9aab862ee0c81da4883f77e15597 682 SMART SM00283 413 674 5.8E-96 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS01535 b77e9aab862ee0c81da4883f77e15597 682 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 511 538 4.2E-20 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS01535 b77e9aab862ee0c81da4883f77e15597 682 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 434 463 4.2E-20 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS01535 b77e9aab862ee0c81da4883f77e15597 682 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 540 569 4.2E-20 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS01535 b77e9aab862ee0c81da4883f77e15597 682 PANTHER PTHR32089 381 677 4.8E-128 T 13-09-2016 THL1_RS01535 b77e9aab862ee0c81da4883f77e15597 682 SUPERFAMILY SSF58104 374 675 2.22E-67 T 13-09-2016 THL1_RS01535 b77e9aab862ee0c81da4883f77e15597 682 Gene3D G3DSA:1.10.287.950 428 645 8.5E-53 T 13-09-2016 THL1_RS01535 b77e9aab862ee0c81da4883f77e15597 682 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 476 673 8.0E-49 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS01535 b77e9aab862ee0c81da4883f77e15597 682 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 39 148 5.9E-25 T 13-09-2016 IPR029095 NarX-like, N-terminal THL1_RS01535 b77e9aab862ee0c81da4883f77e15597 682 PANTHER PTHR32089:SF43 381 677 4.8E-128 T 13-09-2016 THL1_RS21745 e931d3119038d5160a49b2884097b5ec 213 SUPERFAMILY SSF46689 2 80 5.13E-21 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21745 e931d3119038d5160a49b2884097b5ec 213 Gene3D G3DSA:1.10.357.10 62 207 3.0E-25 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS21745 e931d3119038d5160a49b2884097b5ec 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 6.0E-12 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS21745 e931d3119038d5160a49b2884097b5ec 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 6.0E-12 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS21745 e931d3119038d5160a49b2884097b5ec 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.5E-19 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS21745 e931d3119038d5160a49b2884097b5ec 213 PANTHER PTHR30328 1 209 3.0E-40 T 13-09-2016 THL1_RS21745 e931d3119038d5160a49b2884097b5ec 213 PANTHER PTHR30328:SF26 1 209 3.0E-40 T 13-09-2016 THL1_RS21745 e931d3119038d5160a49b2884097b5ec 213 SUPERFAMILY SSF48498 83 200 5.93E-16 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS21745 e931d3119038d5160a49b2884097b5ec 213 Pfam PF08361 MAATS-type transcriptional repressor, C-terminal region 84 204 2.3E-28 T 13-09-2016 IPR013572 Transcription regulator MAATS, C-terminal GO:0003677 THL1_RS21745 e931d3119038d5160a49b2884097b5ec 213 Gene3D G3DSA:1.10.10.60 2 61 3.5E-24 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21745 e931d3119038d5160a49b2884097b5ec 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 13-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site THL1_RS15555 d697b5bbb422f08a0fe28bf060b3e0d6 217 PANTHER PTHR23091:SF240 5 89 3.8E-29 T 13-09-2016 THL1_RS15555 d697b5bbb422f08a0fe28bf060b3e0d6 217 SUPERFAMILY SSF55729 12 204 1.15E-20 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS15555 d697b5bbb422f08a0fe28bf060b3e0d6 217 PANTHER PTHR23091 127 194 3.8E-29 T 13-09-2016 THL1_RS15555 d697b5bbb422f08a0fe28bf060b3e0d6 217 Pfam PF00583 Acetyltransferase (GNAT) family 134 189 8.8E-7 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS15555 d697b5bbb422f08a0fe28bf060b3e0d6 217 PANTHER PTHR23091:SF240 127 194 3.8E-29 T 13-09-2016 THL1_RS15555 d697b5bbb422f08a0fe28bf060b3e0d6 217 Gene3D G3DSA:3.40.630.30 9 196 6.6E-20 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS15555 d697b5bbb422f08a0fe28bf060b3e0d6 217 PANTHER PTHR23091 5 89 3.8E-29 T 13-09-2016 THL1_RS05255 8adfd7482a1ae714d8f94cc3da271f09 418 SMART SM00387 311 415 1.1E-19 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS05255 8adfd7482a1ae714d8f94cc3da271f09 418 PANTHER PTHR24423 1 6 3.0E-27 T 13-09-2016 THL1_RS05255 8adfd7482a1ae714d8f94cc3da271f09 418 PANTHER PTHR24423 179 414 3.0E-27 T 13-09-2016 THL1_RS05255 8adfd7482a1ae714d8f94cc3da271f09 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 393 3.0E-8 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS05255 8adfd7482a1ae714d8f94cc3da271f09 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 374 3.0E-8 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS05255 8adfd7482a1ae714d8f94cc3da271f09 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 360 3.0E-8 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS05255 8adfd7482a1ae714d8f94cc3da271f09 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 412 3.0E-8 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS05255 8adfd7482a1ae714d8f94cc3da271f09 418 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 315 413 8.8E-16 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS05255 8adfd7482a1ae714d8f94cc3da271f09 418 SUPERFAMILY SSF55874 267 413 2.88E-27 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS05255 8adfd7482a1ae714d8f94cc3da271f09 418 Gene3D G3DSA:3.30.565.10 313 413 9.0E-24 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS05255 8adfd7482a1ae714d8f94cc3da271f09 418 SMART SM00388 203 269 0.0067 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS05255 8adfd7482a1ae714d8f94cc3da271f09 418 SUPERFAMILY SSF47384 201 266 2.16E-5 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS04980 7d6ad521a00235f6cb41d7094f536d8e 320 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 13-09-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS04980 7d6ad521a00235f6cb41d7094f536d8e 320 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 16 311 8.6E-95 T 13-09-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS04980 7d6ad521a00235f6cb41d7094f536d8e 320 PANTHER PTHR11079 6 320 1.5E-144 T 13-09-2016 THL1_RS04980 7d6ad521a00235f6cb41d7094f536d8e 320 Pfam PF01479 S4 domain 18 61 2.8E-5 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS04980 7d6ad521a00235f6cb41d7094f536d8e 320 SUPERFAMILY SSF55120 75 315 4.11E-81 T 13-09-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS04980 7d6ad521a00235f6cb41d7094f536d8e 320 Pfam PF00849 RNA pseudouridylate synthase 91 240 3.6E-32 T 13-09-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS04980 7d6ad521a00235f6cb41d7094f536d8e 320 SUPERFAMILY SSF55174 17 104 5.55E-7 T 13-09-2016 THL1_RS04980 7d6ad521a00235f6cb41d7094f536d8e 320 PANTHER PTHR11079:SF73 6 320 1.5E-144 T 13-09-2016 THL1_RS04980 7d6ad521a00235f6cb41d7094f536d8e 320 Gene3D G3DSA:3.10.290.10 18 58 2.7E-5 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 PANTHER PTHR19384 344 848 2.5E-102 T 13-09-2016 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 SUPERFAMILY SSF52218 389 528 6.98E-38 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 Gene3D G3DSA:3.40.50.360 387 528 1.4E-38 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 Gene3D G3DSA:2.40.30.10 546 587 2.8E-9 T 13-09-2016 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 Gene3D G3DSA:2.40.30.10 649 716 2.8E-9 T 13-09-2016 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 Pfam PF03929 PepSY-associated TM region 6 366 2.0E-60 T 13-09-2016 IPR005625 PepSY-associated TM protein THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 SUPERFAMILY SSF52343 709 848 2.36E-38 T 13-09-2016 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 SUPERFAMILY SSF63380 535 707 2.32E-25 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 Pfam PF00258 Flavodoxin 391 519 5.2E-25 T 13-09-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 740 749 4.1E-14 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 753 764 4.1E-14 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 652 659 4.1E-14 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 784 800 4.1E-14 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 716 735 4.1E-14 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 680 689 4.1E-14 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 807 815 4.1E-14 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 577 587 4.1E-14 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 Gene3D G3DSA:3.40.50.80 717 847 1.9E-39 T 13-09-2016 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 Pfam PF00175 Oxidoreductase NAD-binding domain 717 822 3.7E-15 T 13-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 PRINTS PR00369 Flavodoxin signature 438 449 8.1E-7 T 13-09-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 PRINTS PR00369 Flavodoxin signature 469 479 8.1E-7 T 13-09-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 THL1_RS05185 60926b225564e453d8bd378d5ab4b471 848 PRINTS PR00369 Flavodoxin signature 390 403 8.1E-7 T 13-09-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 THL1_RS05190 2c48fdd91fd70f808468c3a085ff1ff0 248 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 3 248 42.701 T 13-09-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF THL1_RS05190 2c48fdd91fd70f808468c3a085ff1ff0 248 PANTHER PTHR30292:SF0 1 247 7.7E-122 T 13-09-2016 THL1_RS05190 2c48fdd91fd70f808468c3a085ff1ff0 248 PANTHER PTHR30292 1 247 7.7E-122 T 13-09-2016 THL1_RS05190 2c48fdd91fd70f808468c3a085ff1ff0 248 Pfam PF03746 LamB/YcsF family 5 245 1.3E-95 T 13-09-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF THL1_RS05190 2c48fdd91fd70f808468c3a085ff1ff0 248 SUPERFAMILY SSF88713 4 246 1.33E-91 T 13-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THL1_RS05225 bae02ca2c2ac0efaa8a2adc176ec2045 533 SUPERFAMILY SSF53850 28 529 5.32E-147 T 13-09-2016 THL1_RS05225 bae02ca2c2ac0efaa8a2adc176ec2045 533 PANTHER PTHR30290 28 530 5.5E-206 T 13-09-2016 THL1_RS05225 bae02ca2c2ac0efaa8a2adc176ec2045 533 Gene3D G3DSA:3.90.76.10 36 216 3.3E-46 T 13-09-2016 THL1_RS05225 bae02ca2c2ac0efaa8a2adc176ec2045 533 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 70 450 1.0E-96 T 13-09-2016 IPR000914 Solute-binding protein family 5 domain THL1_RS05225 bae02ca2c2ac0efaa8a2adc176ec2045 533 PANTHER PTHR30290:SF14 28 530 5.5E-206 T 13-09-2016 THL1_RS05225 bae02ca2c2ac0efaa8a2adc176ec2045 533 Gene3D G3DSA:3.10.105.10 291 502 1.0E-65 T 13-09-2016 THL1_RS05225 bae02ca2c2ac0efaa8a2adc176ec2045 533 PIRSF PIRSF002741 24 529 9.1E-116 T 13-09-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 THL1_RS22170 b8d976b407e069003def7131a8536e2a 141 PANTHER PTHR23089 22 129 2.4E-19 T 13-09-2016 IPR001310 Histidine triad (HIT) protein THL1_RS22170 b8d976b407e069003def7131a8536e2a 141 Pfam PF01230 HIT domain 9 99 1.5E-18 T 13-09-2016 IPR001310 Histidine triad (HIT) protein THL1_RS22170 b8d976b407e069003def7131a8536e2a 141 PANTHER PTHR23089:SF13 22 129 2.4E-19 T 13-09-2016 THL1_RS22170 b8d976b407e069003def7131a8536e2a 141 Gene3D G3DSA:3.30.428.10 4 136 7.7E-37 T 13-09-2016 IPR011146 HIT-like domain GO:0003824 THL1_RS22170 b8d976b407e069003def7131a8536e2a 141 SUPERFAMILY SSF54197 3 133 1.5E-35 T 13-09-2016 IPR011146 HIT-like domain GO:0003824 THL1_RS22170 b8d976b407e069003def7131a8536e2a 141 PIRSF PIRSF000714 1 138 2.4E-50 T 13-09-2016 IPR026026 Histidine triad hydrolase, Hint-type THL1_RS07615 bbcf93d7e5e0cd21e51347419665f922 274 PANTHER PTHR11122:SF14 13 229 5.6E-47 T 13-09-2016 THL1_RS07615 bbcf93d7e5e0cd21e51347419665f922 274 SUPERFAMILY SSF74650 8 250 2.01E-51 T 13-09-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 THL1_RS07615 bbcf93d7e5e0cd21e51347419665f922 274 PIRSF PIRSF016020 3 273 4.1E-45 T 13-09-2016 IPR025532 Glucose-6-phosphate 1-epimerase KEGG: 00010+5.1.3.15 THL1_RS07615 bbcf93d7e5e0cd21e51347419665f922 274 Pfam PF01263 Aldose 1-epimerase 21 267 7.1E-23 T 13-09-2016 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 THL1_RS07615 bbcf93d7e5e0cd21e51347419665f922 274 Gene3D G3DSA:2.70.98.10 12 269 1.3E-56 T 13-09-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 THL1_RS07615 bbcf93d7e5e0cd21e51347419665f922 274 PANTHER PTHR11122 13 229 5.6E-47 T 13-09-2016 THL1_RS25900 1ba0e1dab256f833ba0121652c30b6f5 343 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 82 334 6.0E-75 T 13-09-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 THL1_RS25900 1ba0e1dab256f833ba0121652c30b6f5 343 SUPERFAMILY SSF52540 118 337 1.04E-56 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25900 1ba0e1dab256f833ba0121652c30b6f5 343 Pfam PF03193 Protein of unknown function, DUF258 104 277 9.5E-55 T 13-09-2016 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 THL1_RS25900 1ba0e1dab256f833ba0121652c30b6f5 343 SUPERFAMILY SSF50249 45 107 2.48E-5 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS25900 1ba0e1dab256f833ba0121652c30b6f5 343 Gene3D G3DSA:1.10.40.50 279 341 2.5E-21 T 13-09-2016 THL1_RS25900 1ba0e1dab256f833ba0121652c30b6f5 343 Gene3D G3DSA:3.40.50.300 119 277 3.0E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25900 1ba0e1dab256f833ba0121652c30b6f5 343 PANTHER PTHR32120 3 342 2.8E-143 T 13-09-2016 THL1_RS25900 1ba0e1dab256f833ba0121652c30b6f5 343 PANTHER PTHR32120:SF2 3 342 2.8E-143 T 13-09-2016 THL1_RS25900 1ba0e1dab256f833ba0121652c30b6f5 343 Gene3D G3DSA:2.40.50.140 44 102 1.1E-4 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS25900 1ba0e1dab256f833ba0121652c30b6f5 343 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 45 342 36.697 T 13-09-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 THL1_RS20615 ef6e6b93d71000376272562d29bfeec1 415 Gene3D G3DSA:1.10.630.10 13 410 7.3E-90 T 13-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 THL1_RS20615 ef6e6b93d71000376272562d29bfeec1 415 SUPERFAMILY SSF48264 14 409 4.85E-74 T 13-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 THL1_RS20615 ef6e6b93d71000376272562d29bfeec1 415 PANTHER PTHR11712 64 415 1.4E-48 T 13-09-2016 THL1_RS20615 ef6e6b93d71000376272562d29bfeec1 415 Pfam PF00067 Cytochrome P450 285 373 9.7E-7 T 13-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 THL1_RS20615 ef6e6b93d71000376272562d29bfeec1 415 PRINTS PR00385 P450 superfamily signature 358 369 7.5E-5 T 13-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 THL1_RS20615 ef6e6b93d71000376272562d29bfeec1 415 PRINTS PR00385 P450 superfamily signature 349 358 7.5E-5 T 13-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 THL1_RS20615 ef6e6b93d71000376272562d29bfeec1 415 PRINTS PR00385 P450 superfamily signature 249 266 7.5E-5 T 13-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 THL1_RS20615 ef6e6b93d71000376272562d29bfeec1 415 PRINTS PR00385 P450 superfamily signature 284 295 7.5E-5 T 13-09-2016 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 Reactome: REACT_13433 THL1_RS20615 ef6e6b93d71000376272562d29bfeec1 415 PRINTS PR00359 B-class P450 signature 203 225 6.5E-23 T 13-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 THL1_RS20615 ef6e6b93d71000376272562d29bfeec1 415 PRINTS PR00359 B-class P450 signature 104 115 6.5E-23 T 13-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 THL1_RS20615 ef6e6b93d71000376272562d29bfeec1 415 PRINTS PR00359 B-class P450 signature 150 166 6.5E-23 T 13-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 THL1_RS20615 ef6e6b93d71000376272562d29bfeec1 415 PRINTS PR00359 B-class P450 signature 300 327 6.5E-23 T 13-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 THL1_RS20615 ef6e6b93d71000376272562d29bfeec1 415 PRINTS PR00359 B-class P450 signature 358 369 6.5E-23 T 13-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 THL1_RS20615 ef6e6b93d71000376272562d29bfeec1 415 PRINTS PR00359 B-class P450 signature 349 358 6.5E-23 T 13-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 THL1_RS20615 ef6e6b93d71000376272562d29bfeec1 415 PRINTS PR00359 B-class P450 signature 167 182 6.5E-23 T 13-09-2016 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 THL1_RS20615 ef6e6b93d71000376272562d29bfeec1 415 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 351 360 - T 13-09-2016 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 Reactome: REACT_13433 THL1_RS01150 fb29bba51575a80e2c2e106f8c483fe9 159 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 36.825 T 13-09-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 THL1_RS01150 fb29bba51575a80e2c2e106f8c483fe9 159 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 156 2.6E-60 T 13-09-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 THL1_RS01150 fb29bba51575a80e2c2e106f8c483fe9 159 PANTHER PTHR21342:SF1 1 159 1.8E-84 T 13-09-2016 THL1_RS01150 fb29bba51575a80e2c2e106f8c483fe9 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 1.4E-51 T 13-09-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 THL1_RS01150 fb29bba51575a80e2c2e106f8c483fe9 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 1.4E-51 T 13-09-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 THL1_RS01150 fb29bba51575a80e2c2e106f8c483fe9 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 1.4E-51 T 13-09-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 THL1_RS01150 fb29bba51575a80e2c2e106f8c483fe9 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 1.4E-51 T 13-09-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 THL1_RS01150 fb29bba51575a80e2c2e106f8c483fe9 159 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 1.4E-51 T 13-09-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 THL1_RS01150 fb29bba51575a80e2c2e106f8c483fe9 159 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 81 1.0E-4 T 13-09-2016 THL1_RS01150 fb29bba51575a80e2c2e106f8c483fe9 159 Pfam PF01467 Cytidylyltransferase-like 5 133 2.7E-24 T 13-09-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THL1_RS01150 fb29bba51575a80e2c2e106f8c483fe9 159 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 63 8.9E-20 T 13-09-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THL1_RS01150 fb29bba51575a80e2c2e106f8c483fe9 159 PANTHER PTHR21342 1 159 1.8E-84 T 13-09-2016 THL1_RS01150 fb29bba51575a80e2c2e106f8c483fe9 159 Gene3D G3DSA:3.40.50.620 1 157 1.0E-56 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS01150 fb29bba51575a80e2c2e106f8c483fe9 159 SUPERFAMILY SSF52374 1 156 4.56E-47 T 13-09-2016 THL1_RS10745 846392d7bc0641f611b6214c9d182594 194 Pfam PF07238 PilZ domain 100 177 7.5E-12 T 13-09-2016 IPR009875 PilZ domain GO:0035438 THL1_RS10745 846392d7bc0641f611b6214c9d182594 194 Gene3D G3DSA:2.40.10.220 100 188 4.9E-6 T 13-09-2016 THL1_RS09255 dfa027b8f3dd2986281e65f45563f982 346 Gene3D G3DSA:3.40.800.20 3 340 3.1E-76 T 13-09-2016 IPR023801 Histone deacetylase domain THL1_RS09255 dfa027b8f3dd2986281e65f45563f982 346 Pfam PF00850 Histone deacetylase domain 28 339 1.4E-63 T 13-09-2016 IPR023801 Histone deacetylase domain THL1_RS09255 dfa027b8f3dd2986281e65f45563f982 346 PRINTS PR01270 Histone deacetylase superfamily signature 157 180 1.8E-13 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS09255 dfa027b8f3dd2986281e65f45563f982 346 PRINTS PR01270 Histone deacetylase superfamily signature 190 205 1.8E-13 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS09255 dfa027b8f3dd2986281e65f45563f982 346 PRINTS PR01270 Histone deacetylase superfamily signature 276 286 1.8E-13 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS09255 dfa027b8f3dd2986281e65f45563f982 346 SUPERFAMILY SSF52768 2 343 3.5E-89 T 13-09-2016 THL1_RS09255 dfa027b8f3dd2986281e65f45563f982 346 PANTHER PTHR10625:SF121 115 338 3.9E-102 T 13-09-2016 THL1_RS09255 dfa027b8f3dd2986281e65f45563f982 346 PANTHER PTHR10625:SF121 4 85 3.9E-102 T 13-09-2016 THL1_RS09255 dfa027b8f3dd2986281e65f45563f982 346 PANTHER PTHR10625 115 338 3.9E-102 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS09255 dfa027b8f3dd2986281e65f45563f982 346 PANTHER PTHR10625 4 85 3.9E-102 T 13-09-2016 IPR000286 Histone deacetylase superfamily THL1_RS16370 f3286051882b566fca538ed1c39d1e09 233 Pfam PF04333 MlaA lipoprotein 33 222 4.9E-76 T 13-09-2016 IPR007428 MlaA lipoprotein GO:0016020 THL1_RS16370 f3286051882b566fca538ed1c39d1e09 233 PANTHER PTHR30035 6 232 3.4E-81 T 13-09-2016 IPR007428 MlaA lipoprotein GO:0016020 THL1_RS16370 f3286051882b566fca538ed1c39d1e09 233 PANTHER PTHR30035:SF3 6 232 3.4E-81 T 13-09-2016 THL1_RS16370 f3286051882b566fca538ed1c39d1e09 233 PRINTS PR01805 VacJ lipoprotein signature 102 119 5.2E-28 T 13-09-2016 IPR007428 MlaA lipoprotein GO:0016020 THL1_RS16370 f3286051882b566fca538ed1c39d1e09 233 PRINTS PR01805 VacJ lipoprotein signature 51 67 5.2E-28 T 13-09-2016 IPR007428 MlaA lipoprotein GO:0016020 THL1_RS16370 f3286051882b566fca538ed1c39d1e09 233 PRINTS PR01805 VacJ lipoprotein signature 138 155 5.2E-28 T 13-09-2016 IPR007428 MlaA lipoprotein GO:0016020 THL1_RS16370 f3286051882b566fca538ed1c39d1e09 233 PRINTS PR01805 VacJ lipoprotein signature 34 47 5.2E-28 T 13-09-2016 IPR007428 MlaA lipoprotein GO:0016020 THL1_RS09175 e483a1f5ebdb654c587d2c11d72c4b49 257 PANTHER PTHR11907 1 252 2.2E-115 T 13-09-2016 THL1_RS09175 e483a1f5ebdb654c587d2c11d72c4b49 257 Pfam PF13230 Glutamine amidotransferases class-II 1 254 8.1E-108 T 13-09-2016 IPR026869 Putative glutamine amidotransferase type 2 THL1_RS09175 e483a1f5ebdb654c587d2c11d72c4b49 257 SUPERFAMILY SSF56235 2 251 2.98E-50 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS09175 e483a1f5ebdb654c587d2c11d72c4b49 257 PANTHER PTHR11907:SF10 1 252 2.2E-115 T 13-09-2016 THL1_RS09175 e483a1f5ebdb654c587d2c11d72c4b49 257 Gene3D G3DSA:3.60.20.10 1 253 1.7E-64 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS10770 07614d6235185b1ef379bf582b3b5bf2 741 Pfam PF03772 Competence protein 200 464 1.2E-56 T 13-09-2016 IPR004477 ComEC/Rec2-related protein THL1_RS10770 07614d6235185b1ef379bf582b3b5bf2 741 SUPERFAMILY SSF56281 491 719 1.57E-44 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS10770 07614d6235185b1ef379bf582b3b5bf2 741 Pfam PF00753 Metallo-beta-lactamase superfamily 501 687 8.8E-17 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS10770 07614d6235185b1ef379bf582b3b5bf2 741 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 221 399 1.5E-20 T 13-09-2016 IPR004477 ComEC/Rec2-related protein THL1_RS10770 07614d6235185b1ef379bf582b3b5bf2 741 SMART SM00849 503 687 3.1E-15 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS10770 07614d6235185b1ef379bf582b3b5bf2 741 PANTHER PTHR30619 1 722 1.0E-171 T 13-09-2016 THL1_RS10770 07614d6235185b1ef379bf582b3b5bf2 741 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 113 716 9.0E-91 T 13-09-2016 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 THL1_RS10770 07614d6235185b1ef379bf582b3b5bf2 741 Pfam PF13567 Domain of unknown function (DUF4131) 9 167 8.6E-26 T 13-09-2016 IPR025405 Domain of unknown function DUF4131 THL1_RS10770 07614d6235185b1ef379bf582b3b5bf2 741 Gene3D G3DSA:3.60.15.10 491 708 3.1E-30 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS10770 07614d6235185b1ef379bf582b3b5bf2 741 PANTHER PTHR30619:SF2 1 722 1.0E-171 T 13-09-2016 THL1_RS07045 eceb68e984926f490f0ef0103b481fe9 292 Pfam PF01144 Coenzyme A transferase 5 199 9.4E-31 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS07045 eceb68e984926f490f0ef0103b481fe9 292 PANTHER PTHR13707:SF34 1 251 1.7E-48 T 13-09-2016 THL1_RS07045 eceb68e984926f490f0ef0103b481fe9 292 SMART SM00882 4 221 3.5E-27 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS07045 eceb68e984926f490f0ef0103b481fe9 292 SUPERFAMILY SSF100950 2 287 5.18E-74 T 13-09-2016 THL1_RS07045 eceb68e984926f490f0ef0103b481fe9 292 Gene3D G3DSA:3.40.1080.10 154 285 9.8E-79 T 13-09-2016 THL1_RS07045 eceb68e984926f490f0ef0103b481fe9 292 Gene3D G3DSA:3.40.1080.10 2 116 9.8E-79 T 13-09-2016 THL1_RS07045 eceb68e984926f490f0ef0103b481fe9 292 PANTHER PTHR13707 1 251 1.7E-48 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS05815 6e085479f89c7c303a83c96d8c20bf56 330 Gene3D G3DSA:3.40.50.150 119 219 5.9E-11 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS05815 6e085479f89c7c303a83c96d8c20bf56 330 PANTHER PTHR13393:SF0 7 325 2.8E-131 T 13-09-2016 THL1_RS05815 6e085479f89c7c303a83c96d8c20bf56 330 Hamap MF_01848 Ribosomal RNA large subunit methyltransferase F [rlmF]. 21 320 55.372 T 13-09-2016 IPR016909 Ribosomal RNA large subunit methyltransferase F GO:0005737|GO:0006364|GO:0008988 THL1_RS05815 6e085479f89c7c303a83c96d8c20bf56 330 SUPERFAMILY SSF53335 59 317 2.05E-29 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS05815 6e085479f89c7c303a83c96d8c20bf56 330 PIRSF PIRSF029038 11 330 9.6E-155 T 13-09-2016 IPR016909 Ribosomal RNA large subunit methyltransferase F GO:0005737|GO:0006364|GO:0008988 THL1_RS05815 6e085479f89c7c303a83c96d8c20bf56 330 Pfam PF05971 Protein of unknown function (DUF890) 21 318 8.0E-136 T 13-09-2016 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 THL1_RS05815 6e085479f89c7c303a83c96d8c20bf56 330 PANTHER PTHR13393 7 325 2.8E-131 T 13-09-2016 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 THL1_RS21645 08c519f276e2c529a140b4494627321d 252 PANTHER PTHR30363:SF1 1 252 3.9E-112 T 13-09-2016 THL1_RS21645 08c519f276e2c529a140b4494627321d 252 SMART SM01134 73 233 1.6E-73 T 13-09-2016 THL1_RS21645 08c519f276e2c529a140b4494627321d 252 Pfam PF00455 DeoR C terminal sensor domain 75 232 1.2E-53 T 13-09-2016 IPR014036 DeoR C-terminal sensor domain THL1_RS21645 08c519f276e2c529a140b4494627321d 252 SUPERFAMILY SSF46785 3 67 4.13E-15 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS21645 08c519f276e2c529a140b4494627321d 252 Pfam PF08220 DeoR-like helix-turn-helix domain 6 59 1.9E-20 T 13-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 THL1_RS21645 08c519f276e2c529a140b4494627321d 252 PANTHER PTHR30363 1 252 3.9E-112 T 13-09-2016 THL1_RS21645 08c519f276e2c529a140b4494627321d 252 Gene3D G3DSA:3.30.750.70 76 147 1.4E-13 T 13-09-2016 THL1_RS21645 08c519f276e2c529a140b4494627321d 252 SMART SM00420 6 58 6.7E-23 T 13-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 THL1_RS21645 08c519f276e2c529a140b4494627321d 252 SUPERFAMILY SSF100950 75 233 2.4E-30 T 13-09-2016 THL1_RS21645 08c519f276e2c529a140b4494627321d 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 5.8E-12 T 13-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 THL1_RS21645 08c519f276e2c529a140b4494627321d 252 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 5.8E-12 T 13-09-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 THL1_RS21645 08c519f276e2c529a140b4494627321d 252 Gene3D G3DSA:1.10.10.10 1 57 7.7E-12 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13690 985188a7fe3fce276107d742ffbcb1d0 428 SUPERFAMILY SSF51905 29 253 1.49E-41 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS13690 985188a7fe3fce276107d742ffbcb1d0 428 SUPERFAMILY SSF51905 345 395 1.49E-41 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS13690 985188a7fe3fce276107d742ffbcb1d0 428 Gene3D G3DSA:3.30.9.10 124 174 1.5E-4 T 13-09-2016 THL1_RS13690 985188a7fe3fce276107d742ffbcb1d0 428 Gene3D G3DSA:3.50.50.60 175 252 5.0E-46 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS13690 985188a7fe3fce276107d742ffbcb1d0 428 Gene3D G3DSA:3.50.50.60 25 119 5.0E-46 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS13690 985188a7fe3fce276107d742ffbcb1d0 428 Gene3D G3DSA:3.50.50.60 345 390 5.0E-46 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS13690 985188a7fe3fce276107d742ffbcb1d0 428 Pfam PF01266 FAD dependent oxidoreductase 30 381 4.2E-53 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS13690 985188a7fe3fce276107d742ffbcb1d0 428 PANTHER PTHR13847 8 384 9.5E-153 T 13-09-2016 THL1_RS13690 985188a7fe3fce276107d742ffbcb1d0 428 PANTHER PTHR13847:SF190 8 384 9.5E-153 T 13-09-2016 THL1_RS15925 a6514ef6b8b781e17ca63ef46fdb983d 302 Gene3D G3DSA:3.40.190.10 176 261 1.1E-17 T 13-09-2016 THL1_RS15925 a6514ef6b8b781e17ca63ef46fdb983d 302 Gene3D G3DSA:3.40.190.10 90 175 5.3E-21 T 13-09-2016 THL1_RS15925 a6514ef6b8b781e17ca63ef46fdb983d 302 PANTHER PTHR30419 1 301 2.6E-108 T 13-09-2016 THL1_RS15925 a6514ef6b8b781e17ca63ef46fdb983d 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.9E-21 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS15925 a6514ef6b8b781e17ca63ef46fdb983d 302 SUPERFAMILY SSF46785 1 110 9.09E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS15925 a6514ef6b8b781e17ca63ef46fdb983d 302 PANTHER PTHR30419:SF3 1 301 2.6E-108 T 13-09-2016 THL1_RS15925 a6514ef6b8b781e17ca63ef46fdb983d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.7E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS15925 a6514ef6b8b781e17ca63ef46fdb983d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.7E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS15925 a6514ef6b8b781e17ca63ef46fdb983d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.7E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS15925 a6514ef6b8b781e17ca63ef46fdb983d 302 Gene3D G3DSA:1.10.10.10 1 84 1.2E-28 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS15925 a6514ef6b8b781e17ca63ef46fdb983d 302 Pfam PF03466 LysR substrate binding domain 91 289 6.9E-40 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS15925 a6514ef6b8b781e17ca63ef46fdb983d 302 SUPERFAMILY SSF53850 91 291 4.24E-39 T 13-09-2016 THL1_RS19225 912beef9886228fdf3b18d95135bc47c 246 Gene3D G3DSA:3.40.50.720 9 244 1.1E-63 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS19225 912beef9886228fdf3b18d95135bc47c 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 213 0.0052 T 13-09-2016 THL1_RS19225 912beef9886228fdf3b18d95135bc47c 246 PANTHER PTHR24322 166 198 3.8E-90 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19225 912beef9886228fdf3b18d95135bc47c 246 Pfam PF00106 short chain dehydrogenase 15 210 2.2E-46 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19225 912beef9886228fdf3b18d95135bc47c 246 SUPERFAMILY SSF51735 11 243 9.12E-59 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS19225 912beef9886228fdf3b18d95135bc47c 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS19225 912beef9886228fdf3b18d95135bc47c 246 PANTHER PTHR24322 18 150 3.8E-90 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19225 912beef9886228fdf3b18d95135bc47c 246 PANTHER PTHR24322:SF337 166 198 3.8E-90 T 13-09-2016 THL1_RS19225 912beef9886228fdf3b18d95135bc47c 246 PANTHER PTHR24322:SF337 18 150 3.8E-90 T 13-09-2016 THL1_RS19225 912beef9886228fdf3b18d95135bc47c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 1.5E-22 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19225 912beef9886228fdf3b18d95135bc47c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 1.5E-22 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19225 912beef9886228fdf3b18d95135bc47c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 1.5E-22 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19225 912beef9886228fdf3b18d95135bc47c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 1.5E-22 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19225 912beef9886228fdf3b18d95135bc47c 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.5E-22 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS24890 7e4b8c2335b858a35fe0975096aef1b1 251 Gene3D G3DSA:2.60.120.620 4 209 3.6E-22 T 13-09-2016 THL1_RS24890 7e4b8c2335b858a35fe0975096aef1b1 251 SUPERFAMILY SSF51197 5 230 8.97E-35 T 13-09-2016 THL1_RS24890 7e4b8c2335b858a35fe0975096aef1b1 251 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 13 199 1.4E-15 T 13-09-2016 IPR008775 Phytanoyl-CoA dioxygenase THL1_RS05855 dcdb4978f70c9e1bb88b8499f18fe62d 373 PANTHER PTHR33529 2 373 1.3E-111 T 13-09-2016 THL1_RS05855 dcdb4978f70c9e1bb88b8499f18fe62d 373 Pfam PF03739 Predicted permease YjgP/YjgQ family 5 353 3.8E-73 T 13-09-2016 IPR005495 Permease LptG/LptF-related GO:0016021 THL1_RS05855 dcdb4978f70c9e1bb88b8499f18fe62d 373 PANTHER PTHR33529:SF2 2 373 1.3E-111 T 13-09-2016 THL1_RS05855 dcdb4978f70c9e1bb88b8499f18fe62d 373 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 2 354 1.8E-117 T 13-09-2016 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 THL1_RS07855 0f8460b8d22b8ab446e16f03a47210b5 234 SMART SM00895 88 214 2.2E-11 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS07855 0f8460b8d22b8ab446e16f03a47210b5 234 SUPERFAMILY SSF46785 18 87 1.58E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07855 0f8460b8d22b8ab446e16f03a47210b5 234 PANTHER PTHR11751 20 104 1.4E-20 T 13-09-2016 THL1_RS07855 0f8460b8d22b8ab446e16f03a47210b5 234 Pfam PF07729 FCD domain 98 211 2.3E-18 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS07855 0f8460b8d22b8ab446e16f03a47210b5 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 78 1.6E-18 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS07855 0f8460b8d22b8ab446e16f03a47210b5 234 PANTHER PTHR11751:SF362 20 104 1.4E-20 T 13-09-2016 THL1_RS07855 0f8460b8d22b8ab446e16f03a47210b5 234 SMART SM00345 20 78 1.4E-16 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS07855 0f8460b8d22b8ab446e16f03a47210b5 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 8.4E-6 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS07855 0f8460b8d22b8ab446e16f03a47210b5 234 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 8.4E-6 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS07855 0f8460b8d22b8ab446e16f03a47210b5 234 Gene3D G3DSA:1.10.10.10 14 80 5.8E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07855 0f8460b8d22b8ab446e16f03a47210b5 234 Gene3D G3DSA:1.20.120.530 99 226 6.3E-23 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS07855 0f8460b8d22b8ab446e16f03a47210b5 234 SUPERFAMILY SSF48008 99 223 3.66E-21 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS00585 a2c02f9177c630b21b8eebd5ccf3c639 330 PIRSF PIRSF500176 3 326 1.2E-80 T 13-09-2016 THL1_RS00585 a2c02f9177c630b21b8eebd5ccf3c639 330 PANTHER PTHR11707 3 328 3.3E-88 T 13-09-2016 THL1_RS00585 a2c02f9177c630b21b8eebd5ccf3c639 330 Gene3D G3DSA:3.40.50.40 207 328 1.1E-32 T 13-09-2016 IPR027473 L-asparaginase, C-terminal domain THL1_RS00585 a2c02f9177c630b21b8eebd5ccf3c639 330 SUPERFAMILY SSF53774 4 329 5.36E-81 T 13-09-2016 IPR006034 Asparaginase/glutaminase GO:0006520 THL1_RS00585 a2c02f9177c630b21b8eebd5ccf3c639 330 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 87 97 - T 13-09-2016 IPR027475 Asparaginase/glutaminase, active site 2 THL1_RS00585 a2c02f9177c630b21b8eebd5ccf3c639 330 PANTHER PTHR11707:SF3 3 328 3.3E-88 T 13-09-2016 THL1_RS00585 a2c02f9177c630b21b8eebd5ccf3c639 330 SMART SM00870 6 317 1.1E-85 T 13-09-2016 IPR006034 Asparaginase/glutaminase GO:0006520 THL1_RS00585 a2c02f9177c630b21b8eebd5ccf3c639 330 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 9 17 - T 13-09-2016 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 THL1_RS00585 a2c02f9177c630b21b8eebd5ccf3c639 330 Gene3D G3DSA:3.40.50.1170 3 181 1.3E-49 T 13-09-2016 IPR027474 L-asparaginase, N-terminal THL1_RS00585 a2c02f9177c630b21b8eebd5ccf3c639 330 PIRSF PIRSF001220 1 328 3.8E-70 T 13-09-2016 IPR006034 Asparaginase/glutaminase GO:0006520 THL1_RS00585 a2c02f9177c630b21b8eebd5ccf3c639 330 Pfam PF00710 Asparaginase, N-terminal 6 180 7.6E-44 T 13-09-2016 IPR027474 L-asparaginase, N-terminal THL1_RS00585 a2c02f9177c630b21b8eebd5ccf3c639 330 PRINTS PR00139 Asparaginase/glutaminase family signature 254 272 6.9E-12 T 13-09-2016 IPR006034 Asparaginase/glutaminase GO:0006520 THL1_RS00585 a2c02f9177c630b21b8eebd5ccf3c639 330 PRINTS PR00139 Asparaginase/glutaminase family signature 7 18 6.9E-12 T 13-09-2016 IPR006034 Asparaginase/glutaminase GO:0006520 THL1_RS00585 a2c02f9177c630b21b8eebd5ccf3c639 330 PRINTS PR00139 Asparaginase/glutaminase family signature 86 104 6.9E-12 T 13-09-2016 IPR006034 Asparaginase/glutaminase GO:0006520 THL1_RS18890 66c22c392e60b9ba5c166208448119d9 278 PANTHER PTHR39456:SF2 2 277 2.9E-136 T 13-09-2016 THL1_RS18890 66c22c392e60b9ba5c166208448119d9 278 Pfam PF10118 Predicted metal-dependent hydrolase 16 261 2.8E-91 T 13-09-2016 IPR016516 Uncharacterised conserved protein UCP07580 THL1_RS18890 66c22c392e60b9ba5c166208448119d9 278 PANTHER PTHR39456 2 277 2.9E-136 T 13-09-2016 THL1_RS18890 66c22c392e60b9ba5c166208448119d9 278 PIRSF PIRSF007580 1 277 3.7E-93 T 13-09-2016 IPR016516 Uncharacterised conserved protein UCP07580 THL1_RS28200 0bb111c3390ff259a63acf1b7abf8fec 124 Gene3D G3DSA:3.40.30.10 16 103 1.0E-10 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS28200 0bb111c3390ff259a63acf1b7abf8fec 124 SUPERFAMILY SSF52833 19 120 5.28E-15 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS01575 366272f28f2889d473ea1daa85922fac 184 Gene3D G3DSA:1.20.950.20 91 172 4.2E-4 T 13-09-2016 THL1_RS01575 366272f28f2889d473ea1daa85922fac 184 PANTHER PTHR30529:SF5 2 184 4.7E-87 T 13-09-2016 THL1_RS01575 366272f28f2889d473ea1daa85922fac 184 Pfam PF01292 Prokaryotic cytochrome b561 9 180 1.5E-28 T 13-09-2016 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THL1_RS01575 366272f28f2889d473ea1daa85922fac 184 SUPERFAMILY SSF81342 4 180 1.73E-38 T 13-09-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 THL1_RS01575 366272f28f2889d473ea1daa85922fac 184 PANTHER PTHR30529 2 184 4.7E-87 T 13-09-2016 THL1_RS11065 f1eab22235fcde7c96ed8f578b8918ef 161 PANTHER PTHR36155 1 161 7.5E-95 T 13-09-2016 THL1_RS11065 f1eab22235fcde7c96ed8f578b8918ef 161 PANTHER PTHR36155:SF1 1 161 7.5E-95 T 13-09-2016 THL1_RS11065 f1eab22235fcde7c96ed8f578b8918ef 161 Pfam PF04008 Adenosine specific kinase 6 160 5.8E-73 T 13-09-2016 IPR007153 Adenosine specific kinase THL1_RS11065 f1eab22235fcde7c96ed8f578b8918ef 161 SUPERFAMILY SSF103165 1 161 6.15E-72 T 13-09-2016 IPR007153 Adenosine specific kinase THL1_RS11065 f1eab22235fcde7c96ed8f578b8918ef 161 Gene3D G3DSA:3.40.1520.10 1 161 4.5E-77 T 13-09-2016 IPR007153 Adenosine specific kinase THL1_RS27345 faa5302bf5838d9e067d4ad2d03cf345 276 Gene3D G3DSA:3.40.50.1820 47 270 8.2E-33 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS27345 faa5302bf5838d9e067d4ad2d03cf345 276 Pfam PF01738 Dienelactone hydrolase family 50 270 2.5E-14 T 13-09-2016 IPR002925 Dienelactone hydrolase GO:0016787 THL1_RS27345 faa5302bf5838d9e067d4ad2d03cf345 276 SUPERFAMILY SSF53474 47 273 5.22E-30 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS05890 50bbb0c134251073a12c5c202b49ba6d 113 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 28 105 1.1E-28 T 13-09-2016 IPR003849 Preprotein translocase YajC THL1_RS05890 50bbb0c134251073a12c5c202b49ba6d 113 PRINTS PR01853 Bacterial YajC preprotein translocase signature 63 81 6.0E-12 T 13-09-2016 IPR003849 Preprotein translocase YajC THL1_RS05890 50bbb0c134251073a12c5c202b49ba6d 113 PRINTS PR01853 Bacterial YajC preprotein translocase signature 25 45 6.0E-12 T 13-09-2016 IPR003849 Preprotein translocase YajC THL1_RS05890 50bbb0c134251073a12c5c202b49ba6d 113 PANTHER PTHR33909:SF1 3 113 3.9E-34 T 13-09-2016 THL1_RS05890 50bbb0c134251073a12c5c202b49ba6d 113 SMART SM01323 23 105 4.6E-40 T 13-09-2016 IPR003849 Preprotein translocase YajC THL1_RS05890 50bbb0c134251073a12c5c202b49ba6d 113 PANTHER PTHR33909 3 113 3.9E-34 T 13-09-2016 THL1_RS05890 50bbb0c134251073a12c5c202b49ba6d 113 Pfam PF02699 Preprotein translocase subunit 29 102 3.6E-28 T 13-09-2016 IPR003849 Preprotein translocase YajC THL1_RS19745 3f88ca145af76e5ea72611145478818d 533 PIRSF PIRSF002741 17 531 1.6E-60 T 13-09-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 THL1_RS19745 3f88ca145af76e5ea72611145478818d 533 Gene3D G3DSA:3.10.105.10 312 497 2.0E-33 T 13-09-2016 THL1_RS19745 3f88ca145af76e5ea72611145478818d 533 Gene3D G3DSA:3.40.190.10 211 311 2.0E-25 T 13-09-2016 THL1_RS19745 3f88ca145af76e5ea72611145478818d 533 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 18 39 4.9E-5 T 13-09-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THL1_RS19745 3f88ca145af76e5ea72611145478818d 533 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 17 46 2.7E-6 T 13-09-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THL1_RS19745 3f88ca145af76e5ea72611145478818d 533 PANTHER PTHR30290 10 531 4.8E-87 T 13-09-2016 THL1_RS19745 3f88ca145af76e5ea72611145478818d 533 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 100 416 7.3E-63 T 13-09-2016 IPR000914 Solute-binding protein family 5 domain THL1_RS19745 3f88ca145af76e5ea72611145478818d 533 Gene3D G3DSA:3.90.76.10 68 210 1.5E-33 T 13-09-2016 THL1_RS19745 3f88ca145af76e5ea72611145478818d 533 SUPERFAMILY SSF53850 51 527 6.33E-107 T 13-09-2016 THL1_RS05870 00ad3e73fc91c7d7c2b8e6e9e43eee96 70 PRINTS PR00050 Cold shock protein signature 7 22 1.2E-17 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS05870 00ad3e73fc91c7d7c2b8e6e9e43eee96 70 PRINTS PR00050 Cold shock protein signature 42 60 1.2E-17 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS05870 00ad3e73fc91c7d7c2b8e6e9e43eee96 70 PRINTS PR00050 Cold shock protein signature 27 36 1.2E-17 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS05870 00ad3e73fc91c7d7c2b8e6e9e43eee96 70 PANTHER PTHR11544 1 70 8.1E-41 T 13-09-2016 THL1_RS05870 00ad3e73fc91c7d7c2b8e6e9e43eee96 70 Gene3D G3DSA:2.40.50.140 4 69 2.4E-31 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS05870 00ad3e73fc91c7d7c2b8e6e9e43eee96 70 PANTHER PTHR11544:SF63 1 70 8.1E-41 T 13-09-2016 THL1_RS05870 00ad3e73fc91c7d7c2b8e6e9e43eee96 70 SUPERFAMILY SSF50249 3 69 6.64E-25 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS05870 00ad3e73fc91c7d7c2b8e6e9e43eee96 70 Pfam PF00313 'Cold-shock' DNA-binding domain 6 68 7.1E-29 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS05870 00ad3e73fc91c7d7c2b8e6e9e43eee96 70 SMART SM00357 6 69 9.3E-28 T 13-09-2016 IPR011129 Cold shock protein GO:0003676 THL1_RS05870 00ad3e73fc91c7d7c2b8e6e9e43eee96 70 PIRSF PIRSF002599 1 70 1.8E-23 T 13-09-2016 IPR012156 Cold shock, CspA GO:0003676 THL1_RS05870 00ad3e73fc91c7d7c2b8e6e9e43eee96 70 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 36 - T 13-09-2016 IPR019844 Cold-shock conserved site THL1_RS07485 59c22b425da8d155b8de9e1caa87fe3c 456 Pfam PF00743 Flavin-binding monooxygenase-like 3 227 5.3E-33 T 13-09-2016 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 THL1_RS07485 59c22b425da8d155b8de9e1caa87fe3c 456 Pfam PF00743 Flavin-binding monooxygenase-like 244 381 3.7E-11 T 13-09-2016 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 THL1_RS07485 59c22b425da8d155b8de9e1caa87fe3c 456 PANTHER PTHR23023:SF124 1 407 9.3E-111 T 13-09-2016 THL1_RS07485 59c22b425da8d155b8de9e1caa87fe3c 456 Gene3D G3DSA:3.50.50.60 169 271 1.0E-19 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07485 59c22b425da8d155b8de9e1caa87fe3c 456 SUPERFAMILY SSF51905 1 242 4.75E-50 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07485 59c22b425da8d155b8de9e1caa87fe3c 456 SUPERFAMILY SSF51905 254 368 1.29E-8 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07485 59c22b425da8d155b8de9e1caa87fe3c 456 Gene3D G3DSA:3.50.50.60 272 416 3.1E-56 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07485 59c22b425da8d155b8de9e1caa87fe3c 456 Gene3D G3DSA:3.50.50.60 2 168 3.1E-56 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07485 59c22b425da8d155b8de9e1caa87fe3c 456 PANTHER PTHR23023 1 407 9.3E-111 T 13-09-2016 THL1_RS06915 33e09568aa7d4860eacfa6b4f812329b 219 Pfam PF11153 Protein of unknown function (DUF2931) 4 217 1.1E-29 T 13-09-2016 IPR021326 Protein of unknown function DUF2931 THL1_RS16830 8f875588825f6aa07824ec24934344a3 279 PANTHER PTHR20883 15 248 1.6E-54 T 13-09-2016 THL1_RS16830 8f875588825f6aa07824ec24934344a3 279 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 18 227 1.2E-18 T 13-09-2016 IPR008775 Phytanoyl-CoA dioxygenase THL1_RS16830 8f875588825f6aa07824ec24934344a3 279 SUPERFAMILY SSF51197 7 274 1.19E-62 T 13-09-2016 THL1_RS16830 8f875588825f6aa07824ec24934344a3 279 Gene3D G3DSA:2.60.120.620 5 249 1.2E-54 T 13-09-2016 THL1_RS16830 8f875588825f6aa07824ec24934344a3 279 PANTHER PTHR20883:SF11 15 248 1.6E-54 T 13-09-2016 THL1_RS26825 4c58126ff9bb0cfbca9e37e23e53284c 669 SMART SM00267 212 384 3.5E-68 T 13-09-2016 IPR000160 GGDEF domain THL1_RS26825 4c58126ff9bb0cfbca9e37e23e53284c 669 Pfam PF13185 GAF domain 62 211 4.1E-12 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS26825 4c58126ff9bb0cfbca9e37e23e53284c 669 PANTHER PTHR10799:SF710 176 494 9.7E-81 T 13-09-2016 THL1_RS26825 4c58126ff9bb0cfbca9e37e23e53284c 669 SMART SM00052 394 642 1.2E-113 T 13-09-2016 IPR001633 EAL domain THL1_RS26825 4c58126ff9bb0cfbca9e37e23e53284c 669 SUPERFAMILY SSF55073 227 385 1.8E-49 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS26825 4c58126ff9bb0cfbca9e37e23e53284c 669 PANTHER PTHR10799 176 494 9.7E-81 T 13-09-2016 THL1_RS26825 4c58126ff9bb0cfbca9e37e23e53284c 669 Gene3D G3DSA:3.30.450.40 39 219 4.0E-18 T 13-09-2016 IPR029016 GAF domain-like THL1_RS26825 4c58126ff9bb0cfbca9e37e23e53284c 669 Pfam PF00563 EAL domain 401 635 3.1E-76 T 13-09-2016 IPR001633 EAL domain THL1_RS26825 4c58126ff9bb0cfbca9e37e23e53284c 669 SUPERFAMILY SSF141868 399 651 8.76E-89 T 13-09-2016 IPR001633 EAL domain THL1_RS26825 4c58126ff9bb0cfbca9e37e23e53284c 669 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 222 383 2.7E-42 T 13-09-2016 IPR000160 GGDEF domain THL1_RS26825 4c58126ff9bb0cfbca9e37e23e53284c 669 Pfam PF00990 Diguanylate cyclase, GGDEF domain 222 379 2.7E-49 T 13-09-2016 IPR000160 GGDEF domain THL1_RS26825 4c58126ff9bb0cfbca9e37e23e53284c 669 SUPERFAMILY SSF55781 44 218 6.98E-14 T 13-09-2016 IPR029016 GAF domain-like THL1_RS26825 4c58126ff9bb0cfbca9e37e23e53284c 669 Gene3D G3DSA:3.30.70.270 223 390 1.4E-58 T 13-09-2016 THL1_RS26825 4c58126ff9bb0cfbca9e37e23e53284c 669 Gene3D G3DSA:3.20.20.450 397 649 1.6E-102 T 13-09-2016 IPR001633 EAL domain THL1_RS26825 4c58126ff9bb0cfbca9e37e23e53284c 669 SMART SM00065 63 220 0.0024 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 Pfam PF13533 Biotin-lipoyl like 86 124 2.4E-7 T 13-09-2016 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 SUPERFAMILY SSF111369 84 141 2.35E-6 T 13-09-2016 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 PANTHER PTHR30386:SF4 24 132 1.9E-129 T 13-09-2016 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 PANTHER PTHR30386 163 452 1.9E-129 T 13-09-2016 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 PANTHER PTHR30386 24 132 1.9E-129 T 13-09-2016 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 PANTHER PTHR30386:SF4 163 452 1.9E-129 T 13-09-2016 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 37 452 1.1E-126 T 13-09-2016 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 Gene3D G3DSA:2.40.50.100 80 111 9.8E-16 T 13-09-2016 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 Gene3D G3DSA:2.40.50.100 301 335 9.8E-16 T 13-09-2016 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 Pfam PF13437 HlyD family secretion protein 304 412 1.2E-16 T 13-09-2016 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 431 451 3.3E-42 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 349 373 3.3E-42 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 373 396 3.3E-42 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 416 431 3.3E-42 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 47 70 3.3E-42 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 316 337 3.3E-42 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 89 109 3.3E-42 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS21445 5a29ceb9232504b533d2c947fe35637e 452 ProSitePatterns PS00543 HlyD family secretion proteins signature. 416 438 - T 13-09-2016 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 THL1_RS14410 07fee47ef4dc5c30a88c656686caf077 443 Gene3D G3DSA:1.20.1250.20 254 434 3.1E-24 T 13-09-2016 THL1_RS14410 07fee47ef4dc5c30a88c656686caf077 443 Gene3D G3DSA:1.20.1250.20 16 197 1.2E-34 T 13-09-2016 THL1_RS14410 07fee47ef4dc5c30a88c656686caf077 443 Pfam PF07690 Major Facilitator Superfamily 27 315 1.4E-35 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS14410 07fee47ef4dc5c30a88c656686caf077 443 SUPERFAMILY SSF103473 6 433 6.8E-82 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS14410 07fee47ef4dc5c30a88c656686caf077 443 PANTHER PTHR24064 2 422 1.5E-80 T 13-09-2016 THL1_RS14410 07fee47ef4dc5c30a88c656686caf077 443 PANTHER PTHR24064:SF234 2 422 1.5E-80 T 13-09-2016 THL1_RS14410 07fee47ef4dc5c30a88c656686caf077 443 ProSitePatterns PS00217 Sugar transport proteins signature 2. 118 143 - T 13-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 THL1_RS21295 b3e50f70a768fbbdaad1b4cdc9ef291d 229 ProSitePatterns PS00517 Ribonuclease III family signature. 37 45 - T 13-09-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 THL1_RS21295 b3e50f70a768fbbdaad1b4cdc9ef291d 229 PANTHER PTHR11207 5 219 1.2E-89 T 13-09-2016 THL1_RS21295 b3e50f70a768fbbdaad1b4cdc9ef291d 229 SUPERFAMILY SSF54768 108 226 2.51E-25 T 13-09-2016 THL1_RS21295 b3e50f70a768fbbdaad1b4cdc9ef291d 229 Pfam PF14622 Ribonuclease-III-like 18 142 1.3E-36 T 13-09-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 THL1_RS21295 b3e50f70a768fbbdaad1b4cdc9ef291d 229 SMART SM00358 155 223 1.8E-16 T 13-09-2016 IPR014720 Double-stranded RNA-binding domain THL1_RS21295 b3e50f70a768fbbdaad1b4cdc9ef291d 229 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 8 220 4.0E-71 T 13-09-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 THL1_RS21295 b3e50f70a768fbbdaad1b4cdc9ef291d 229 Gene3D G3DSA:1.10.1520.10 5 142 1.0E-47 T 13-09-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 THL1_RS21295 b3e50f70a768fbbdaad1b4cdc9ef291d 229 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 219 30.64 T 13-09-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 THL1_RS21295 b3e50f70a768fbbdaad1b4cdc9ef291d 229 Gene3D G3DSA:3.30.160.20 152 223 8.7E-22 T 13-09-2016 IPR014720 Double-stranded RNA-binding domain THL1_RS21295 b3e50f70a768fbbdaad1b4cdc9ef291d 229 Pfam PF00035 Double-stranded RNA binding motif 155 219 4.1E-8 T 13-09-2016 IPR014720 Double-stranded RNA-binding domain THL1_RS21295 b3e50f70a768fbbdaad1b4cdc9ef291d 229 SMART SM00535 20 148 1.2E-56 T 13-09-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 THL1_RS21295 b3e50f70a768fbbdaad1b4cdc9ef291d 229 SUPERFAMILY SSF69065 3 157 3.31E-50 T 13-09-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 THL1_RS12640 282d2749a81e27eb199c178027c6937b 271 SUPERFAMILY SSF51658 5 270 3.66E-59 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS12640 282d2749a81e27eb199c178027c6937b 271 PANTHER PTHR12110 1 271 1.4E-86 T 13-09-2016 THL1_RS12640 282d2749a81e27eb199c178027c6937b 271 Pfam PF01261 Xylose isomerase-like TIM barrel 23 221 2.8E-14 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS12640 282d2749a81e27eb199c178027c6937b 271 PANTHER PTHR12110:SF26 1 271 1.4E-86 T 13-09-2016 THL1_RS12640 282d2749a81e27eb199c178027c6937b 271 Gene3D G3DSA:3.20.20.150 6 270 9.7E-38 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS10550 02b34333274da21f5e9f1227b664211e 519 PANTHER PTHR10196:SF65 1 516 4.4E-292 T 13-09-2016 THL1_RS10550 02b34333274da21f5e9f1227b664211e 519 SUPERFAMILY SSF53067 5 254 3.27E-56 T 13-09-2016 THL1_RS10550 02b34333274da21f5e9f1227b664211e 519 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 254 1.9E-40 T 13-09-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 THL1_RS10550 02b34333274da21f5e9f1227b664211e 519 PIRSF PIRSF000538 4 513 2.3E-111 T 13-09-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 THL1_RS10550 02b34333274da21f5e9f1227b664211e 519 Gene3D G3DSA:3.30.420.40 3 255 2.0E-55 T 13-09-2016 THL1_RS10550 02b34333274da21f5e9f1227b664211e 519 SUPERFAMILY SSF53067 258 494 1.11E-53 T 13-09-2016 THL1_RS10550 02b34333274da21f5e9f1227b664211e 519 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 264 457 4.0E-30 T 13-09-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 THL1_RS10550 02b34333274da21f5e9f1227b664211e 519 Gene3D G3DSA:3.30.420.40 258 509 6.6E-48 T 13-09-2016 THL1_RS10550 02b34333274da21f5e9f1227b664211e 519 PANTHER PTHR10196 1 516 4.4E-292 T 13-09-2016 THL1_RS17975 e9a16bf0d585c8a81aeb1a1847d7ab3a 624 Pfam PF13616 PPIC-type PPIASE domain 261 360 5.1E-28 T 13-09-2016 THL1_RS17975 e9a16bf0d585c8a81aeb1a1847d7ab3a 624 SUPERFAMILY SSF54534 262 362 1.11E-31 T 13-09-2016 THL1_RS17975 e9a16bf0d585c8a81aeb1a1847d7ab3a 624 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 300 321 - T 13-09-2016 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site THL1_RS17975 e9a16bf0d585c8a81aeb1a1847d7ab3a 624 Pfam PF13624 SurA N-terminal domain 1 163 2.2E-41 T 13-09-2016 THL1_RS17975 e9a16bf0d585c8a81aeb1a1847d7ab3a 624 PANTHER PTHR10657 1 166 5.9E-127 T 13-09-2016 THL1_RS17975 e9a16bf0d585c8a81aeb1a1847d7ab3a 624 Gene3D G3DSA:3.10.50.40 262 386 3.9E-41 T 13-09-2016 THL1_RS17975 e9a16bf0d585c8a81aeb1a1847d7ab3a 624 PANTHER PTHR10657 199 516 5.9E-127 T 13-09-2016 THL1_RS17975 e9a16bf0d585c8a81aeb1a1847d7ab3a 624 PANTHER PTHR10657:SF11 1 166 5.9E-127 T 13-09-2016 THL1_RS17975 e9a16bf0d585c8a81aeb1a1847d7ab3a 624 PANTHER PTHR10657:SF11 199 516 5.9E-127 T 13-09-2016 THL1_RS17975 e9a16bf0d585c8a81aeb1a1847d7ab3a 624 SUPERFAMILY SSF109998 199 235 1.96E-27 T 13-09-2016 IPR027304 Trigger factor/SurA domain THL1_RS17975 e9a16bf0d585c8a81aeb1a1847d7ab3a 624 SUPERFAMILY SSF109998 43 167 1.96E-27 T 13-09-2016 IPR027304 Trigger factor/SurA domain THL1_RS24515 cf8fc43640c40bdb3d8cca2293493445 106 Pfam PF03658 RnfH family Ubiquitin 6 90 1.0E-27 T 13-09-2016 IPR005346 RnfH protein THL1_RS24515 cf8fc43640c40bdb3d8cca2293493445 106 PANTHER PTHR37483:SF1 3 106 3.4E-31 T 13-09-2016 THL1_RS24515 cf8fc43640c40bdb3d8cca2293493445 106 Hamap MF_00460 Protein RnfH [rnfH]. 6 98 23.014 T 13-09-2016 IPR005346 RnfH protein THL1_RS24515 cf8fc43640c40bdb3d8cca2293493445 106 Gene3D G3DSA:3.10.20.280 4 92 6.4E-29 T 13-09-2016 IPR005346 RnfH protein THL1_RS24515 cf8fc43640c40bdb3d8cca2293493445 106 PANTHER PTHR37483 3 106 3.4E-31 T 13-09-2016 THL1_RS24515 cf8fc43640c40bdb3d8cca2293493445 106 SUPERFAMILY SSF54285 5 82 2.35E-19 T 13-09-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp THL1_RS21915 68701807c0d8f56bad37f43a844cdcae 136 SMART SM00671 89 122 1.9 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS21915 68701807c0d8f56bad37f43a844cdcae 136 SMART SM00671 53 88 15.0 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS21915 68701807c0d8f56bad37f43a844cdcae 136 Gene3D G3DSA:1.25.40.10 43 125 1.1E-12 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS21915 68701807c0d8f56bad37f43a844cdcae 136 PANTHER PTHR11102 42 125 2.0E-12 T 13-09-2016 THL1_RS21915 68701807c0d8f56bad37f43a844cdcae 136 SUPERFAMILY SSF81901 42 130 1.57E-11 T 13-09-2016 THL1_RS21915 68701807c0d8f56bad37f43a844cdcae 136 Pfam PF08238 Sel1 repeat 91 122 4.4E-4 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS21915 68701807c0d8f56bad37f43a844cdcae 136 Pfam PF08238 Sel1 repeat 54 88 0.14 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS24665 880e09298154492dd39e80487c8a9f79 245 Pfam PF13365 Trypsin-like peptidase domain 26 191 8.1E-10 T 13-09-2016 THL1_RS24665 880e09298154492dd39e80487c8a9f79 245 SUPERFAMILY SSF50494 11 238 1.04E-18 T 13-09-2016 IPR009003 Peptidase S1, PA clan THL1_RS24665 880e09298154492dd39e80487c8a9f79 245 Gene3D G3DSA:2.40.10.10 124 214 3.7E-6 T 13-09-2016 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 SUPERFAMILY SSF82866 797 1016 7.06E-43 T 13-09-2016 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 SUPERFAMILY SSF82693 40 133 9.42E-24 T 13-09-2016 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 Gene3D G3DSA:1.10.3850.10 799 1015 2.6E-51 T 13-09-2016 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 PANTHER PTHR32063:SF21 1 1023 0.0 T 13-09-2016 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 Gene3D G3DSA:1.20.1640.10 285 498 4.6E-58 T 13-09-2016 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 PANTHER PTHR32063 1 1023 0.0 T 13-09-2016 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 SUPERFAMILY SSF82693 556 653 9.94E-16 T 13-09-2016 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 SUPERFAMILY SSF82866 290 490 1.15E-46 T 13-09-2016 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 SUPERFAMILY SSF82693 136 182 3.31E-23 T 13-09-2016 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 SUPERFAMILY SSF82693 268 324 3.31E-23 T 13-09-2016 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 1.2E-79 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.2E-79 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.2E-79 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 1.2E-79 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.2E-79 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.2E-79 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 1.2E-79 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.2E-79 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 PRINTS PR00702 Acriflavin resistance protein family signature 610 624 1.2E-79 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 Pfam PF00873 AcrB/AcrD/AcrF family 4 1013 0.0 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 Gene3D G3DSA:3.30.70.1430 40 141 4.2E-30 T 13-09-2016 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 Gene3D G3DSA:3.30.2090.10 708 791 1.3E-17 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 Gene3D G3DSA:3.30.2090.10 184 266 3.5E-16 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 SUPERFAMILY SSF82714 184 266 1.83E-15 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 Gene3D G3DSA:3.30.70.1430 559 647 2.2E-9 T 13-09-2016 THL1_RS15455 4fd42c115213c9657a62e4c4130f7a9f 1030 SUPERFAMILY SSF82714 708 791 1.31E-15 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS27170 0895b501bf44e7c093c070eaacd8c75b 454 Gene3D G3DSA:2.40.320.10 4 216 1.9E-32 T 13-09-2016 IPR023577 CYTH domain THL1_RS27170 0895b501bf44e7c093c070eaacd8c75b 454 PANTHER PTHR39569:SF1 2 454 1.8E-116 T 13-09-2016 THL1_RS27170 0895b501bf44e7c093c070eaacd8c75b 454 SUPERFAMILY SSF55154 1 221 2.45E-41 T 13-09-2016 IPR033469 CYTH-like domain THL1_RS27170 0895b501bf44e7c093c070eaacd8c75b 454 Pfam PF01928 CYTH domain 2 201 2.6E-34 T 13-09-2016 IPR023577 CYTH domain THL1_RS27170 0895b501bf44e7c093c070eaacd8c75b 454 PANTHER PTHR39569 2 454 1.8E-116 T 13-09-2016 THL1_RS27170 0895b501bf44e7c093c070eaacd8c75b 454 SMART SM01118 2 207 8.7E-31 T 13-09-2016 IPR023577 CYTH domain THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 Pfam PF00175 Oxidoreductase NAD-binding domain 277 386 1.1E-17 T 13-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 SUPERFAMILY SSF63380 105 272 1.0E-36 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 PANTHER PTHR19370 1 176 7.3E-140 T 13-09-2016 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 Gene3D G3DSA:2.40.30.10 124 264 5.3E-58 T 13-09-2016 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 Pfam PF00970 Oxidoreductase FAD-binding domain 204 266 6.0E-10 T 13-09-2016 IPR008333 Oxidoreductase, FAD-binding domain THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 SUPERFAMILY SSF54292 39 124 1.08E-23 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 TIGRFAM TIGR01941 nqrF: NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit 5 407 6.7E-227 T 13-09-2016 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 Hamap MF_00430 Na(+)-translocating NADH-quinone reductase subunit F [nqrF]. 3 407 64.237 T 13-09-2016 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 PIRSF PIRSF000044 1 407 1.6E-227 T 13-09-2016 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F GO:0006814|GO:0016021|GO:0016655|GO:0051537|GO:0055114 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 242 251 3.7E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 373 381 3.7E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 209 216 3.7E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 276 295 3.7E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 314 325 3.7E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 Gene3D G3DSA:3.10.20.30 41 123 4.1E-22 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 Gene3D G3DSA:3.40.50.80 276 392 1.9E-42 T 13-09-2016 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 PANTHER PTHR19370:SF32 1 176 7.3E-140 T 13-09-2016 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 PANTHER PTHR19370:SF32 205 407 7.3E-140 T 13-09-2016 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 40 115 3.4E-11 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 PANTHER PTHR19370 205 407 7.3E-140 T 13-09-2016 THL1_RS10715 5244cb339033ce6ef1c7716a1a297a4d 407 SUPERFAMILY SSF52343 257 402 1.26E-37 T 13-09-2016 THL1_RS09480 885ecd2fde403ec74f5f799c618f83c8 167 PIRSF PIRSF017306 2 162 1.6E-49 T 13-09-2016 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705|UniPathway: UPA00395 THL1_RS09480 885ecd2fde403ec74f5f799c618f83c8 167 PANTHER PTHR21221:SF2 1 165 8.5E-103 T 13-09-2016 THL1_RS09480 885ecd2fde403ec74f5f799c618f83c8 167 Gene3D G3DSA:2.60.120.480 2 164 4.5E-61 T 13-09-2016 IPR024060 Ureidoglycolate lyase domain GO:0004848 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705|UniPathway: UPA00395 THL1_RS09480 885ecd2fde403ec74f5f799c618f83c8 167 PANTHER PTHR21221 1 165 8.5E-103 T 13-09-2016 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705|UniPathway: UPA00395 THL1_RS09480 885ecd2fde403ec74f5f799c618f83c8 167 Pfam PF04115 Ureidoglycolate lyase 2 158 6.5E-53 T 13-09-2016 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705|UniPathway: UPA00395 THL1_RS09480 885ecd2fde403ec74f5f799c618f83c8 167 SUPERFAMILY SSF51182 1 162 2.18E-57 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS09480 885ecd2fde403ec74f5f799c618f83c8 167 Hamap MF_00616 Ureidoglycolate lyase [allA]. 2 163 41.62 T 13-09-2016 IPR023525 Ureidoglycolate lyase, bacterial GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705|UniPathway: UPA00395 THL1_RS01565 0bfacf5cd618c19bf131ea383f72230b 468 Gene3D G3DSA:3.40.640.10 66 342 6.7E-94 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS01565 0bfacf5cd618c19bf131ea383f72230b 468 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 3 447 49.858 T 13-09-2016 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62|UniPathway: UPA00078 THL1_RS01565 0bfacf5cd618c19bf131ea383f72230b 468 Gene3D G3DSA:3.90.1150.10 5 65 1.1E-54 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS01565 0bfacf5cd618c19bf131ea383f72230b 468 Gene3D G3DSA:3.90.1150.10 344 445 1.1E-54 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS01565 0bfacf5cd618c19bf131ea383f72230b 468 Pfam PF00202 Aminotransferase class-III 29 439 2.0E-124 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS01565 0bfacf5cd618c19bf131ea383f72230b 468 SUPERFAMILY SSF53383 11 442 6.79E-131 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS01565 0bfacf5cd618c19bf131ea383f72230b 468 PANTHER PTHR11986:SF8 6 452 1.3E-217 T 13-09-2016 THL1_RS01565 0bfacf5cd618c19bf131ea383f72230b 468 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 252 289 - T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS01565 0bfacf5cd618c19bf131ea383f72230b 468 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 15 442 1.0E-175 T 13-09-2016 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62|UniPathway: UPA00078 THL1_RS01565 0bfacf5cd618c19bf131ea383f72230b 468 PANTHER PTHR11986 6 452 1.3E-217 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS19205 70c4d94a3762da062d5aab354e0f0313 358 Gene3D G3DSA:3.40.50.10470 166 348 4.2E-65 T 13-09-2016 THL1_RS19205 70c4d94a3762da062d5aab354e0f0313 358 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 41 341 1.5E-103 T 13-09-2016 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 THL1_RS19205 70c4d94a3762da062d5aab354e0f0313 358 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 10 352 39.464 T 13-09-2016 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 THL1_RS19205 70c4d94a3762da062d5aab354e0f0313 358 Pfam PF01008 Initiation factor 2 subunit family 53 341 3.2E-72 T 13-09-2016 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 THL1_RS19205 70c4d94a3762da062d5aab354e0f0313 358 SUPERFAMILY SSF100950 9 345 7.33E-112 T 13-09-2016 THL1_RS19205 70c4d94a3762da062d5aab354e0f0313 358 Gene3D G3DSA:1.20.120.420 11 165 1.3E-51 T 13-09-2016 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 THL1_RS19205 70c4d94a3762da062d5aab354e0f0313 358 PANTHER PTHR10233:SF6 9 343 2.8E-156 T 13-09-2016 THL1_RS19205 70c4d94a3762da062d5aab354e0f0313 358 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 12 341 3.7E-139 T 13-09-2016 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|UniPathway: UPA00904 THL1_RS19205 70c4d94a3762da062d5aab354e0f0313 358 PANTHER PTHR10233 9 343 2.8E-156 T 13-09-2016 THL1_RS27700 875d8e9724516e28384c369dddb5236b 239 SUPERFAMILY SSF49584 142 233 5.63E-14 T 13-09-2016 IPR016148 Pili assembly chaperone, C-terminal THL1_RS27700 875d8e9724516e28384c369dddb5236b 239 PRINTS PR00969 Pili chaperone signature 25 34 7.9E-24 T 13-09-2016 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 THL1_RS27700 875d8e9724516e28384c369dddb5236b 239 PRINTS PR00969 Pili chaperone signature 99 116 7.9E-24 T 13-09-2016 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 THL1_RS27700 875d8e9724516e28384c369dddb5236b 239 PRINTS PR00969 Pili chaperone signature 71 92 7.9E-24 T 13-09-2016 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 THL1_RS27700 875d8e9724516e28384c369dddb5236b 239 PRINTS PR00969 Pili chaperone signature 161 176 7.9E-24 T 13-09-2016 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 THL1_RS27700 875d8e9724516e28384c369dddb5236b 239 PRINTS PR00969 Pili chaperone signature 122 137 7.9E-24 T 13-09-2016 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 THL1_RS27700 875d8e9724516e28384c369dddb5236b 239 PANTHER PTHR30251:SF0 4 239 2.4E-92 T 13-09-2016 THL1_RS27700 875d8e9724516e28384c369dddb5236b 239 Gene3D G3DSA:2.60.40.360 24 140 1.0E-40 T 13-09-2016 IPR008962 PapD-like THL1_RS27700 875d8e9724516e28384c369dddb5236b 239 PANTHER PTHR30251 4 239 2.4E-92 T 13-09-2016 THL1_RS27700 875d8e9724516e28384c369dddb5236b 239 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 24 140 5.4E-39 T 13-09-2016 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 THL1_RS27700 875d8e9724516e28384c369dddb5236b 239 SUPERFAMILY SSF49354 20 140 2.62E-38 T 13-09-2016 IPR008962 PapD-like THL1_RS27700 875d8e9724516e28384c369dddb5236b 239 Gene3D G3DSA:2.60.40.1070 143 233 1.3E-16 T 13-09-2016 IPR016148 Pili assembly chaperone, C-terminal THL1_RS27700 875d8e9724516e28384c369dddb5236b 239 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 166 231 1.5E-14 T 13-09-2016 IPR016148 Pili assembly chaperone, C-terminal THL1_RS01200 07f810aee4f20180c575f4cab346c541 222 Pfam PF00005 ABC transporter 18 165 5.3E-32 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS01200 07f810aee4f20180c575f4cab346c541 222 PANTHER PTHR24220 3 220 1.5E-114 T 13-09-2016 THL1_RS01200 07f810aee4f20180c575f4cab346c541 222 PANTHER PTHR24220:SF470 3 220 1.5E-114 T 13-09-2016 THL1_RS01200 07f810aee4f20180c575f4cab346c541 222 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 1.8E-86 T 13-09-2016 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 THL1_RS01200 07f810aee4f20180c575f4cab346c541 222 Gene3D G3DSA:3.40.50.300 1 220 1.1E-68 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01200 07f810aee4f20180c575f4cab346c541 222 SMART SM00382 27 213 1.3E-11 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS01200 07f810aee4f20180c575f4cab346c541 222 SUPERFAMILY SSF52540 1 219 2.38E-66 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS23860 95be99c2e2877a58fdec4b28eb19bf21 584 Pfam PF00916 Sulfate permease family 25 408 2.6E-79 T 13-09-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 THL1_RS23860 95be99c2e2877a58fdec4b28eb19bf21 584 Gene3D G3DSA:3.30.750.24 461 561 2.4E-15 T 13-09-2016 IPR002645 STAS domain THL1_RS23860 95be99c2e2877a58fdec4b28eb19bf21 584 PANTHER PTHR11814:SF112 17 584 5.6E-227 T 13-09-2016 THL1_RS23860 95be99c2e2877a58fdec4b28eb19bf21 584 TIGRFAM TIGR00815 sulP: sulfate permease 18 560 4.3E-116 T 13-09-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 THL1_RS23860 95be99c2e2877a58fdec4b28eb19bf21 584 PANTHER PTHR11814 17 584 5.6E-227 T 13-09-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 THL1_RS23860 95be99c2e2877a58fdec4b28eb19bf21 584 SUPERFAMILY SSF52091 459 563 4.51E-17 T 13-09-2016 IPR002645 STAS domain THL1_RS23860 95be99c2e2877a58fdec4b28eb19bf21 584 Pfam PF01740 STAS domain 461 550 2.4E-15 T 13-09-2016 IPR002645 STAS domain THL1_RS21935 0ed61b48560dfcccc40babac6ee0f6e7 471 PANTHER PTHR35369:SF2 1 471 3.5E-164 T 13-09-2016 THL1_RS21935 0ed61b48560dfcccc40babac6ee0f6e7 471 SUPERFAMILY SSF56672 1 227 8.75E-32 T 13-09-2016 THL1_RS21935 0ed61b48560dfcccc40babac6ee0f6e7 471 PANTHER PTHR35369 1 471 3.5E-164 T 13-09-2016 THL1_RS14295 584349a4b482f5884dc03e0e61f0ad11 582 PANTHER PTHR11384:SF3 10 562 3.4E-112 T 13-09-2016 THL1_RS14295 584349a4b482f5884dc03e0e61f0ad11 582 Pfam PF06472 ABC transporter transmembrane region 2 8 266 3.3E-43 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS14295 584349a4b482f5884dc03e0e61f0ad11 582 PANTHER PTHR11384 10 562 3.4E-112 T 13-09-2016 THL1_RS14295 584349a4b482f5884dc03e0e61f0ad11 582 Gene3D G3DSA:3.40.50.300 371 558 1.5E-14 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14295 584349a4b482f5884dc03e0e61f0ad11 582 SUPERFAMILY SSF90123 26 342 1.44E-23 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS14295 584349a4b482f5884dc03e0e61f0ad11 582 SUPERFAMILY SSF52540 368 562 4.7E-13 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14295 584349a4b482f5884dc03e0e61f0ad11 582 Gene3D G3DSA:1.20.1560.10 14 342 3.1E-14 T 13-09-2016 THL1_RS27040 481d017248e6c906c82aabc1fd44bbb6 298 PANTHER PTHR30293:SF0 1 292 1.1E-95 T 13-09-2016 THL1_RS27040 481d017248e6c906c82aabc1fd44bbb6 298 Pfam PF03466 LysR substrate binding domain 87 289 5.6E-30 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS27040 481d017248e6c906c82aabc1fd44bbb6 298 Gene3D G3DSA:3.40.190.10 179 260 9.3E-11 T 13-09-2016 THL1_RS27040 481d017248e6c906c82aabc1fd44bbb6 298 Gene3D G3DSA:1.10.10.10 1 84 6.5E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS27040 481d017248e6c906c82aabc1fd44bbb6 298 Gene3D G3DSA:3.40.190.10 90 178 7.3E-11 T 13-09-2016 THL1_RS27040 481d017248e6c906c82aabc1fd44bbb6 298 SUPERFAMILY SSF53850 88 292 5.97E-29 T 13-09-2016 THL1_RS27040 481d017248e6c906c82aabc1fd44bbb6 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 3.5E-15 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS27040 481d017248e6c906c82aabc1fd44bbb6 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.3E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS27040 481d017248e6c906c82aabc1fd44bbb6 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.3E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS27040 481d017248e6c906c82aabc1fd44bbb6 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.3E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS27040 481d017248e6c906c82aabc1fd44bbb6 298 SUPERFAMILY SSF46785 1 86 1.36E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS27040 481d017248e6c906c82aabc1fd44bbb6 298 PANTHER PTHR30293 1 292 1.1E-95 T 13-09-2016 THL1_RS21425 5fbd27856bea0bda55a92a52082f8978 387 PANTHER PTHR10909:SF305 1 379 7.1E-190 T 13-09-2016 THL1_RS21425 5fbd27856bea0bda55a92a52082f8978 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 1.4E-30 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS21425 5fbd27856bea0bda55a92a52082f8978 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 1.5E-25 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS21425 5fbd27856bea0bda55a92a52082f8978 387 PIRSF PIRSF016578 4 380 8.9E-19 T 13-09-2016 THL1_RS21425 5fbd27856bea0bda55a92a52082f8978 387 Gene3D G3DSA:2.40.110.10 121 216 1.4E-39 T 13-09-2016 THL1_RS21425 5fbd27856bea0bda55a92a52082f8978 387 Gene3D G3DSA:1.20.140.10 217 381 4.8E-67 T 13-09-2016 THL1_RS21425 5fbd27856bea0bda55a92a52082f8978 387 Gene3D G3DSA:1.10.540.10 1 118 4.6E-40 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS21425 5fbd27856bea0bda55a92a52082f8978 387 SUPERFAMILY SSF56645 1 240 6.81E-82 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS21425 5fbd27856bea0bda55a92a52082f8978 387 PANTHER PTHR10909 1 379 7.1E-190 T 13-09-2016 THL1_RS21425 5fbd27856bea0bda55a92a52082f8978 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 377 5.9E-49 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS21425 5fbd27856bea0bda55a92a52082f8978 387 SUPERFAMILY SSF47203 226 379 1.47E-58 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS21425 5fbd27856bea0bda55a92a52082f8978 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS11070 2929bb4da464f551b66629ce91528a7b 304 Gene3D G3DSA:1.10.10.10 4 83 2.5E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11070 2929bb4da464f551b66629ce91528a7b 304 Gene3D G3DSA:3.40.190.10 92 177 2.6E-18 T 13-09-2016 THL1_RS11070 2929bb4da464f551b66629ce91528a7b 304 Pfam PF03466 LysR substrate binding domain 90 291 1.7E-36 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS11070 2929bb4da464f551b66629ce91528a7b 304 PANTHER PTHR30537 1 298 2.2E-91 T 13-09-2016 THL1_RS11070 2929bb4da464f551b66629ce91528a7b 304 PANTHER PTHR30537:SF24 1 298 2.2E-91 T 13-09-2016 THL1_RS11070 2929bb4da464f551b66629ce91528a7b 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 8.1E-17 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS11070 2929bb4da464f551b66629ce91528a7b 304 SUPERFAMILY SSF46785 5 111 3.17E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11070 2929bb4da464f551b66629ce91528a7b 304 Gene3D G3DSA:3.40.190.10 178 257 3.4E-14 T 13-09-2016 THL1_RS11070 2929bb4da464f551b66629ce91528a7b 304 SUPERFAMILY SSF53850 91 292 3.1E-36 T 13-09-2016 THL1_RS10305 27e0e9975b9723cd9d8c28e263935e8d 572 PANTHER PTHR22550 1 517 6.8E-85 T 13-09-2016 THL1_RS10305 27e0e9975b9723cd9d8c28e263935e8d 572 SMART SM00028 403 436 3.9E-6 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS10305 27e0e9975b9723cd9d8c28e263935e8d 572 SUPERFAMILY SSF53300 95 281 1.6E-14 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS10305 27e0e9975b9723cd9d8c28e263935e8d 572 SUPERFAMILY SSF48452 377 482 5.2E-11 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS10305 27e0e9975b9723cd9d8c28e263935e8d 572 SUPERFAMILY SSF48452 536 568 5.2E-11 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS10305 27e0e9975b9723cd9d8c28e263935e8d 572 Pfam PF13519 von Willebrand factor type A domain 95 202 7.9E-11 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS10305 27e0e9975b9723cd9d8c28e263935e8d 572 Gene3D G3DSA:1.25.40.10 539 571 2.5E-10 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS10305 27e0e9975b9723cd9d8c28e263935e8d 572 Gene3D G3DSA:1.25.40.10 380 458 2.5E-10 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS10305 27e0e9975b9723cd9d8c28e263935e8d 572 PANTHER PTHR22550:SF5 1 517 6.8E-85 T 13-09-2016 THL1_RS10305 27e0e9975b9723cd9d8c28e263935e8d 572 Pfam PF00515 Tetratricopeptide repeat 404 435 1.6E-7 T 13-09-2016 IPR001440 Tetratricopeptide repeat 1 GO:0005515 THL1_RS04300 a8cf9e2ebac9418263de734338638f3e 253 Gene3D G3DSA:3.40.50.620 79 212 3.6E-36 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS04300 a8cf9e2ebac9418263de734338638f3e 253 PANTHER PTHR30336 1 250 2.2E-49 T 13-09-2016 THL1_RS04300 a8cf9e2ebac9418263de734338638f3e 253 PANTHER PTHR30336:SF1 1 250 2.2E-49 T 13-09-2016 THL1_RS04300 a8cf9e2ebac9418263de734338638f3e 253 Pfam PF02698 DUF218 domain 81 243 4.4E-29 T 13-09-2016 IPR003848 Domain of unknown function DUF218 THL1_RS01680 2eb0b95e566c4f38e820589cf664f527 285 Gene3D G3DSA:1.10.3150.10 15 235 1.5E-37 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS01680 2eb0b95e566c4f38e820589cf664f527 285 PANTHER PTHR33525 9 169 2.0E-23 T 13-09-2016 THL1_RS01680 2eb0b95e566c4f38e820589cf664f527 285 Pfam PF08668 HDOD domain 25 189 1.4E-28 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS01680 2eb0b95e566c4f38e820589cf664f527 285 SUPERFAMILY SSF109604 16 234 1.41E-34 T 13-09-2016 THL1_RS01680 2eb0b95e566c4f38e820589cf664f527 285 PANTHER PTHR33525:SF3 9 169 2.0E-23 T 13-09-2016 THL1_RS18500 c0f72e21b253eb40eb7c1dade6904174 377 Pfam PF00266 Aminotransferase class-V 16 343 3.4E-54 T 13-09-2016 IPR000192 Aminotransferase class V domain THL1_RS18500 c0f72e21b253eb40eb7c1dade6904174 377 PANTHER PTHR11601 5 374 1.9E-125 T 13-09-2016 THL1_RS18500 c0f72e21b253eb40eb7c1dade6904174 377 Gene3D G3DSA:3.90.1150.10 269 373 5.2E-17 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS18500 c0f72e21b253eb40eb7c1dade6904174 377 PANTHER PTHR11601:SF31 5 374 1.9E-125 T 13-09-2016 THL1_RS18500 c0f72e21b253eb40eb7c1dade6904174 377 Gene3D G3DSA:3.40.640.10 31 268 1.8E-54 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS18500 c0f72e21b253eb40eb7c1dade6904174 377 SUPERFAMILY SSF53383 5 374 6.68E-78 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS16050 7f17c2fb37acd8465dd49b1f7d972755 265 Pfam PF02498 BRO family, N-terminal domain 14 99 8.6E-25 T 13-09-2016 IPR003497 BRO N-terminal domain THL1_RS16050 7f17c2fb37acd8465dd49b1f7d972755 265 PANTHER PTHR36180 1 112 1.5E-33 T 13-09-2016 THL1_RS16050 7f17c2fb37acd8465dd49b1f7d972755 265 SMART SM01040 13 99 2.0E-39 T 13-09-2016 IPR003497 BRO N-terminal domain THL1_RS16050 7f17c2fb37acd8465dd49b1f7d972755 265 PANTHER PTHR36180:SF2 1 112 1.5E-33 T 13-09-2016 THL1_RS28340 6f50aae4cfec3af23046c3190d5fdda4 291 Pfam PF12697 Alpha/beta hydrolase family 31 282 4.6E-15 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS28340 6f50aae4cfec3af23046c3190d5fdda4 291 Gene3D G3DSA:3.40.50.1820 10 288 1.3E-32 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS28340 6f50aae4cfec3af23046c3190d5fdda4 291 PANTHER PTHR10992 178 290 4.7E-19 T 13-09-2016 THL1_RS28340 6f50aae4cfec3af23046c3190d5fdda4 291 PANTHER PTHR10992 3 160 4.7E-19 T 13-09-2016 THL1_RS28340 6f50aae4cfec3af23046c3190d5fdda4 291 SUPERFAMILY SSF53474 11 288 1.86E-35 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS27065 2e6e1bdb1aa58964476485f20b0b49a4 414 PANTHER PTHR11958:SF68 9 401 5.4E-233 T 13-09-2016 THL1_RS27065 2e6e1bdb1aa58964476485f20b0b49a4 414 Gene3D G3DSA:1.10.3860.10 9 399 3.2E-81 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS27065 2e6e1bdb1aa58964476485f20b0b49a4 414 PANTHER PTHR11958 9 401 5.4E-233 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS27065 2e6e1bdb1aa58964476485f20b0b49a4 414 Pfam PF00375 Sodium:dicarboxylate symporter family 17 396 1.0E-61 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS27065 2e6e1bdb1aa58964476485f20b0b49a4 414 Hamap MF_01582 Serine/threonine transporter SstT [sstT]. 5 406 35.886 T 13-09-2016 IPR023025 Serine/threonine transporter SstT GO:0015293|GO:0015826|GO:0032329 THL1_RS27065 2e6e1bdb1aa58964476485f20b0b49a4 414 SUPERFAMILY SSF118215 17 398 3.01E-91 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS27065 2e6e1bdb1aa58964476485f20b0b49a4 414 PRINTS PR00173 Glutamate-aspartate symporter signature 187 206 7.8E-18 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS27065 2e6e1bdb1aa58964476485f20b0b49a4 414 PRINTS PR00173 Glutamate-aspartate symporter signature 324 343 7.8E-18 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS27065 2e6e1bdb1aa58964476485f20b0b49a4 414 PRINTS PR00173 Glutamate-aspartate symporter signature 351 371 7.8E-18 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS27065 2e6e1bdb1aa58964476485f20b0b49a4 414 PRINTS PR00173 Glutamate-aspartate symporter signature 289 315 7.8E-18 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS27065 2e6e1bdb1aa58964476485f20b0b49a4 414 PRINTS PR00173 Glutamate-aspartate symporter signature 12 32 7.8E-18 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS27065 2e6e1bdb1aa58964476485f20b0b49a4 414 PRINTS PR00173 Glutamate-aspartate symporter signature 43 68 7.8E-18 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS23650 50cac711b357db43cd5cea5b35b5380f 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 3.5E-7 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS23650 50cac711b357db43cd5cea5b35b5380f 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 3.5E-7 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS23650 50cac711b357db43cd5cea5b35b5380f 200 SUPERFAMILY SSF48498 84 198 1.86E-20 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS23650 50cac711b357db43cd5cea5b35b5380f 200 Gene3D G3DSA:1.10.357.10 11 198 3.0E-39 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS23650 50cac711b357db43cd5cea5b35b5380f 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 3.3E-15 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS23650 50cac711b357db43cd5cea5b35b5380f 200 Pfam PF16925 Bacterial transcriptional repressor C-terminal 84 193 1.2E-17 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS23650 50cac711b357db43cd5cea5b35b5380f 200 SUPERFAMILY SSF46689 7 79 4.99E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS23650 50cac711b357db43cd5cea5b35b5380f 200 PANTHER PTHR30055:SF46 1 198 2.4E-75 T 13-09-2016 THL1_RS23650 50cac711b357db43cd5cea5b35b5380f 200 PANTHER PTHR30055 1 198 2.4E-75 T 13-09-2016 THL1_RS15635 0079a883371992516dcbcafc0767f4c5 107 SUPERFAMILY SSF69131 29 107 8.37E-43 T 13-09-2016 IPR015084 Quinohemoprotein amine dehydrogenase, gamma subunit, structural domain GO:0016638|GO:0055114 THL1_RS15635 0079a883371992516dcbcafc0767f4c5 107 Gene3D G3DSA:4.10.940.10 29 107 8.7E-48 T 13-09-2016 IPR015084 Quinohemoprotein amine dehydrogenase, gamma subunit, structural domain GO:0016638|GO:0055114 THL1_RS15635 0079a883371992516dcbcafc0767f4c5 107 Pfam PF08992 Quinohemoprotein amine dehydrogenase, gamma subunit 31 105 3.4E-44 T 13-09-2016 IPR015084 Quinohemoprotein amine dehydrogenase, gamma subunit, structural domain GO:0016638|GO:0055114 THL1_RS15635 0079a883371992516dcbcafc0767f4c5 107 ProDom PD591508 QUINOHEMOPROTEIN AMINE SUBUNIT DEHYDROGENASE GAMMA 1.4.99.- CATALYTIC QH-AMDH CTQ 3D-STRUCTURE 37 107 1.0E-35 T 13-09-2016 IPR015084 Quinohemoprotein amine dehydrogenase, gamma subunit, structural domain GO:0016638|GO:0055114 THL1_RS08700 9d51fc5c7b5cf275d8be3dc05e90be6a 86 Pfam PF12021 Protein of unknown function (DUF3509) 8 75 5.5E-14 T 13-09-2016 IPR021898 Protein of unknown function DUF3509 THL1_RS24350 f3385881d992a79fee9ffef6688fe07d 101 Pfam PF11006 Protein of unknown function (DUF2845) 22 97 6.1E-22 T 13-09-2016 IPR021268 Protein of unknown function DUF2845 THL1_RS11665 4eaf5f1d4d34093304645967c11e6459 611 Pfam PF07715 TonB-dependent Receptor Plug Domain 6 63 1.8E-7 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS11665 4eaf5f1d4d34093304645967c11e6459 611 Gene3D G3DSA:2.170.130.10 3 75 1.4E-15 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS11665 4eaf5f1d4d34093304645967c11e6459 611 PANTHER PTHR32552:SF10 6 611 2.1E-153 T 13-09-2016 THL1_RS11665 4eaf5f1d4d34093304645967c11e6459 611 PANTHER PTHR32552 6 611 2.1E-153 T 13-09-2016 THL1_RS11665 4eaf5f1d4d34093304645967c11e6459 611 Gene3D G3DSA:2.40.170.20 78 611 8.1E-157 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS11665 4eaf5f1d4d34093304645967c11e6459 611 Pfam PF00593 TonB dependent receptor 375 610 2.3E-30 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS11665 4eaf5f1d4d34093304645967c11e6459 611 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 9 611 2.7E-109 T 13-09-2016 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 THL1_RS11665 4eaf5f1d4d34093304645967c11e6459 611 SUPERFAMILY SSF56935 3 611 2.02E-120 T 13-09-2016 THL1_RS25475 242dd68dfa1c0efc04c0c61a799555f4 292 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 291 33.522 T 13-09-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 THL1_RS25475 242dd68dfa1c0efc04c0c61a799555f4 292 PIRSF PIRSF000401 1 292 1.7E-89 T 13-09-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 THL1_RS25475 242dd68dfa1c0efc04c0c61a799555f4 292 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 285 1.7E-90 T 13-09-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 THL1_RS25475 242dd68dfa1c0efc04c0c61a799555f4 292 Gene3D G3DSA:3.40.50.150 97 285 1.0E-40 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS25475 242dd68dfa1c0efc04c0c61a799555f4 292 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 291 1.1E-98 T 13-09-2016 THL1_RS25475 242dd68dfa1c0efc04c0c61a799555f4 292 PANTHER PTHR18895:SF69 16 292 2.4E-157 T 13-09-2016 THL1_RS25475 242dd68dfa1c0efc04c0c61a799555f4 292 SUPERFAMILY SSF53335 51 287 6.23E-45 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS25475 242dd68dfa1c0efc04c0c61a799555f4 292 PANTHER PTHR18895 16 292 2.4E-157 T 13-09-2016 THL1_RS05230 da0b10e67b4d6e72eef4881eea93156b 187 SUPERFAMILY SSF51182 57 179 4.07E-28 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS05230 da0b10e67b4d6e72eef4881eea93156b 187 SMART SM00530 9 64 8.0E-9 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS05230 da0b10e67b4d6e72eef4881eea93156b 187 Gene3D G3DSA:1.10.260.40 4 58 1.8E-17 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS05230 da0b10e67b4d6e72eef4881eea93156b 187 SUPERFAMILY SSF47413 2 69 9.57E-14 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS05230 da0b10e67b4d6e72eef4881eea93156b 187 Pfam PF07883 Cupin domain 109 175 2.9E-17 T 13-09-2016 IPR013096 Cupin 2, conserved barrel THL1_RS05230 da0b10e67b4d6e72eef4881eea93156b 187 Pfam PF13560 Helix-turn-helix domain 5 62 2.0E-9 T 13-09-2016 THL1_RS05230 da0b10e67b4d6e72eef4881eea93156b 187 PANTHER PTHR10245:SF53 4 183 2.8E-61 T 13-09-2016 THL1_RS05230 da0b10e67b4d6e72eef4881eea93156b 187 PANTHER PTHR10245 4 183 2.8E-61 T 13-09-2016 THL1_RS05230 da0b10e67b4d6e72eef4881eea93156b 187 Gene3D G3DSA:2.60.120.10 59 181 4.5E-24 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS25915 524a4b75f8ccc7ce14f110af4e6441dc 508 SUPERFAMILY SSF109604 18 235 6.91E-24 T 13-09-2016 THL1_RS25915 524a4b75f8ccc7ce14f110af4e6441dc 508 Gene3D G3DSA:1.10.3150.10 20 241 1.3E-16 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS25915 524a4b75f8ccc7ce14f110af4e6441dc 508 Pfam PF08668 HDOD domain 23 206 3.6E-11 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS19335 ca2c96a143e8bb9ac84da1b2ba88bb98 250 Gene3D G3DSA:1.10.10.60 151 200 2.1E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19335 ca2c96a143e8bb9ac84da1b2ba88bb98 250 PANTHER PTHR11019 8 246 4.3E-69 T 13-09-2016 THL1_RS19335 ca2c96a143e8bb9ac84da1b2ba88bb98 250 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 215 230 3.2E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS19335 ca2c96a143e8bb9ac84da1b2ba88bb98 250 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 230 246 3.2E-5 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS19335 ca2c96a143e8bb9ac84da1b2ba88bb98 250 Gene3D G3DSA:1.10.10.60 201 249 2.4E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19335 ca2c96a143e8bb9ac84da1b2ba88bb98 250 SMART SM00342 163 246 5.4E-26 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS19335 ca2c96a143e8bb9ac84da1b2ba88bb98 250 SUPERFAMILY SSF46689 199 248 1.52E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19335 ca2c96a143e8bb9ac84da1b2ba88bb98 250 SUPERFAMILY SSF51182 16 116 5.42E-8 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS19335 ca2c96a143e8bb9ac84da1b2ba88bb98 250 PANTHER PTHR11019:SF85 8 246 4.3E-69 T 13-09-2016 THL1_RS19335 ca2c96a143e8bb9ac84da1b2ba88bb98 250 SUPERFAMILY SSF46689 152 197 2.2E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS19335 ca2c96a143e8bb9ac84da1b2ba88bb98 250 Gene3D G3DSA:2.60.120.10 16 75 1.8E-7 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS19335 ca2c96a143e8bb9ac84da1b2ba88bb98 250 Pfam PF12833 Helix-turn-helix domain 169 247 8.8E-19 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS16905 8dbdc3081726a2aa4800f9a62c5c46e5 151 PANTHER PTHR11624 48 65 3.5E-12 T 13-09-2016 IPR033247 Transketolase family THL1_RS16905 8dbdc3081726a2aa4800f9a62c5c46e5 151 SUPERFAMILY SSF52518 6 65 2.18E-15 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS16905 8dbdc3081726a2aa4800f9a62c5c46e5 151 PANTHER PTHR11624:SF72 9 30 3.5E-12 T 13-09-2016 THL1_RS16905 8dbdc3081726a2aa4800f9a62c5c46e5 151 PANTHER PTHR11624:SF72 48 65 3.5E-12 T 13-09-2016 THL1_RS16905 8dbdc3081726a2aa4800f9a62c5c46e5 151 Gene3D G3DSA:3.40.50.970 2 66 4.7E-20 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS16905 8dbdc3081726a2aa4800f9a62c5c46e5 151 PANTHER PTHR11624 9 30 3.5E-12 T 13-09-2016 IPR033247 Transketolase family THL1_RS27315 747563d3efb0353d58d974bbe5f09561 419 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 1.2E-23 T 13-09-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS27315 747563d3efb0353d58d974bbe5f09561 419 SMART SM00357 52 118 2.5E-19 T 13-09-2016 IPR011129 Cold shock protein GO:0003676 THL1_RS27315 747563d3efb0353d58d974bbe5f09561 419 SMART SM00382 170 355 1.1E-8 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS27315 747563d3efb0353d58d974bbe5f09561 419 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 2.3E-32 T 13-09-2016 IPR011113 Rho termination factor, RNA-binding GO:0003723|GO:0006353 THL1_RS27315 747563d3efb0353d58d974bbe5f09561 419 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 4.9E-15 T 13-09-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 THL1_RS27315 747563d3efb0353d58d974bbe5f09561 419 SUPERFAMILY SSF50249 49 125 9.42E-30 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS27315 747563d3efb0353d58d974bbe5f09561 419 PANTHER PTHR15184 47 418 5.9E-196 T 13-09-2016 THL1_RS27315 747563d3efb0353d58d974bbe5f09561 419 SMART SM00959 5 47 2.6E-15 T 13-09-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 THL1_RS27315 747563d3efb0353d58d974bbe5f09561 419 SUPERFAMILY SSF52540 90 371 6.21E-68 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27315 747563d3efb0353d58d974bbe5f09561 419 Gene3D G3DSA:1.10.720.10 1 47 9.2E-20 T 13-09-2016 THL1_RS27315 747563d3efb0353d58d974bbe5f09561 419 SUPERFAMILY SSF68912 1 46 4.71E-11 T 13-09-2016 IPR011112 Rho termination factor, N-terminal GO:0006353 THL1_RS27315 747563d3efb0353d58d974bbe5f09561 419 Gene3D G3DSA:3.40.50.300 132 418 5.7E-107 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27315 747563d3efb0353d58d974bbe5f09561 419 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 2.2E-217 T 13-09-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 THL1_RS27315 747563d3efb0353d58d974bbe5f09561 419 PANTHER PTHR15184:SF34 47 418 5.9E-196 T 13-09-2016 THL1_RS27315 747563d3efb0353d58d974bbe5f09561 419 Gene3D G3DSA:2.40.50.140 49 117 1.4E-36 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS27315 747563d3efb0353d58d974bbe5f09561 419 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 251.693 T 13-09-2016 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 THL1_RS10165 b6950861e17eb53154db61068af7e98c 129 PANTHER PTHR38779 1 102 1.2E-34 T 13-09-2016 THL1_RS10165 b6950861e17eb53154db61068af7e98c 129 Pfam PF02501 Type II secretion system (T2SS), protein I 40 126 1.8E-27 T 13-09-2016 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 THL1_RS10165 b6950861e17eb53154db61068af7e98c 129 Pfam PF13633 Prokaryotic N-terminal methylation site 5 27 2.5E-8 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS10165 b6950861e17eb53154db61068af7e98c 129 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 26 3.4E-7 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS10165 b6950861e17eb53154db61068af7e98c 129 SUPERFAMILY SSF54523 38 107 1.31E-20 T 13-09-2016 THL1_RS10165 b6950861e17eb53154db61068af7e98c 129 Gene3D G3DSA:3.30.1300.30 34 125 1.5E-23 T 13-09-2016 THL1_RS10165 b6950861e17eb53154db61068af7e98c 129 PANTHER PTHR38779:SF2 1 102 1.2E-34 T 13-09-2016 THL1_RS10165 b6950861e17eb53154db61068af7e98c 129 TIGRFAM TIGR01707 gspI: type II secretion system protein I 7 103 2.7E-37 T 13-09-2016 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 THL1_RS22715 21e212471316d40cebc141a18fb12235 331 Pfam PF14238 Domain of unknown function (DUF4340) 74 248 1.9E-14 T 13-09-2016 IPR025641 Domain of unknown function DUF4340 THL1_RS15695 fe42fcd0defaddb69e40a3750c212478 257 Gene3D G3DSA:1.10.12.10 199 257 2.1E-22 T 13-09-2016 IPR014748 Crontonase, C-terminal THL1_RS15695 fe42fcd0defaddb69e40a3750c212478 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 13-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THL1_RS15695 fe42fcd0defaddb69e40a3750c212478 257 Gene3D G3DSA:3.90.226.10 11 196 5.9E-68 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS15695 fe42fcd0defaddb69e40a3750c212478 257 SUPERFAMILY SSF52096 10 256 1.83E-83 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS15695 fe42fcd0defaddb69e40a3750c212478 257 PANTHER PTHR11941:SF54 10 254 2.5E-107 T 13-09-2016 THL1_RS15695 fe42fcd0defaddb69e40a3750c212478 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 257 7.9E-74 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS15695 fe42fcd0defaddb69e40a3750c212478 257 PANTHER PTHR11941 10 254 2.5E-107 T 13-09-2016 THL1_RS26810 6822aa964cbe4a11c7b0a33bea23ff97 583 Pfam PF06048 Domain of unknown function (DUF927) 38 316 4.4E-84 T 13-09-2016 IPR009270 Domain of unknown function DUF927 THL1_RS26615 791c55e7d5d77303cc19b007f41887dc 592 Pfam PF00884 Sulfatase 240 527 5.4E-47 T 13-09-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 THL1_RS26615 791c55e7d5d77303cc19b007f41887dc 592 SUPERFAMILY SSF53649 241 553 6.54E-31 T 13-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THL1_RS26615 791c55e7d5d77303cc19b007f41887dc 592 Gene3D G3DSA:3.40.720.10 242 532 3.1E-17 T 13-09-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THL1_RS26615 791c55e7d5d77303cc19b007f41887dc 592 PANTHER PTHR30443:SF2 8 574 1.3E-294 T 13-09-2016 THL1_RS26615 791c55e7d5d77303cc19b007f41887dc 592 PANTHER PTHR30443 8 574 1.3E-294 T 13-09-2016 THL1_RS00775 f375f921498a955ce39c5cfd7d139ce1 306 PIRSF PIRSF000446 2 299 4.8E-61 T 13-09-2016 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388|UniPathway: UPA00094 THL1_RS00775 f375f921498a955ce39c5cfd7d139ce1 306 SUPERFAMILY SSF55048 120 186 1.22E-11 T 13-09-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 THL1_RS00775 f375f921498a955ce39c5cfd7d139ce1 306 Gene3D G3DSA:3.30.70.250 122 185 2.9E-15 T 13-09-2016 THL1_RS00775 f375f921498a955ce39c5cfd7d139ce1 306 Gene3D G3DSA:3.40.366.10 4 114 2.1E-46 T 13-09-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 THL1_RS00775 f375f921498a955ce39c5cfd7d139ce1 306 Gene3D G3DSA:3.40.366.10 186 286 2.1E-46 T 13-09-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 THL1_RS00775 f375f921498a955ce39c5cfd7d139ce1 306 SUPERFAMILY SSF52151 4 120 5.23E-50 T 13-09-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THL1_RS00775 f375f921498a955ce39c5cfd7d139ce1 306 SUPERFAMILY SSF52151 187 286 5.23E-50 T 13-09-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THL1_RS00775 f375f921498a955ce39c5cfd7d139ce1 306 PANTHER PTHR10982 5 276 1.6E-78 T 13-09-2016 THL1_RS00775 f375f921498a955ce39c5cfd7d139ce1 306 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 301 2.4E-18 T 13-09-2016 IPR020801 Polyketide synthase, acyl transferase domain THL1_RS00775 f375f921498a955ce39c5cfd7d139ce1 306 TIGRFAM TIGR03131 malonate_mdcH: malonate decarboxylase, epsilon subunit 4 294 5.7E-105 T 13-09-2016 IPR017554 Malonate decarboxylase, McdH subunit THL1_RS00775 f375f921498a955ce39c5cfd7d139ce1 306 Pfam PF00698 Acyl transferase domain 5 280 2.6E-24 T 13-09-2016 IPR014043 Acyl transferase THL1_RS06860 3413c6012db022fec24036645e395007 384 PANTHER PTHR23523 2 383 7.2E-74 T 13-09-2016 THL1_RS06860 3413c6012db022fec24036645e395007 384 Gene3D G3DSA:1.20.1250.20 10 187 4.6E-15 T 13-09-2016 THL1_RS06860 3413c6012db022fec24036645e395007 384 Gene3D G3DSA:1.20.1250.20 200 382 7.6E-14 T 13-09-2016 THL1_RS06860 3413c6012db022fec24036645e395007 384 Pfam PF07690 Major Facilitator Superfamily 25 322 2.6E-24 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS06860 3413c6012db022fec24036645e395007 384 PANTHER PTHR23523:SF2 2 383 7.2E-74 T 13-09-2016 THL1_RS06860 3413c6012db022fec24036645e395007 384 SUPERFAMILY SSF103473 6 383 2.09E-43 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 Gene3D G3DSA:3.90.320.10 899 1174 2.0E-74 T 13-09-2016 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 3 1172 13.599 T 13-09-2016 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 PANTHER PTHR11070:SF23 104 198 8.9E-230 T 13-09-2016 THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 SUPERFAMILY SSF52540 315 752 2.95E-108 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 SUPERFAMILY SSF52540 104 181 2.95E-108 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 SUPERFAMILY SSF52540 11 67 2.95E-108 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 SUPERFAMILY SSF52540 782 806 2.95E-108 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 Gene3D G3DSA:1.10.3170.10 141 337 2.0E-32 T 13-09-2016 THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 PANTHER PTHR11070 290 474 8.9E-230 T 13-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 PANTHER PTHR11070 104 198 8.9E-230 T 13-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 PANTHER PTHR11070 3 76 8.9E-230 T 13-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 PANTHER PTHR11070:SF23 290 474 8.9E-230 T 13-09-2016 THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 PANTHER PTHR11070:SF23 781 1167 8.9E-230 T 13-09-2016 THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 PANTHER PTHR11070:SF23 3 76 8.9E-230 T 13-09-2016 THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 Gene3D G3DSA:3.40.50.300 341 437 3.4E-52 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 Gene3D G3DSA:3.40.50.300 106 136 3.4E-52 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 Gene3D G3DSA:3.40.50.300 7 69 3.4E-52 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 3 1171 2.7E-265 T 13-09-2016 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 Gene3D G3DSA:3.40.50.300 712 811 9.5E-54 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 Gene3D G3DSA:3.40.50.300 438 565 9.5E-54 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 424 1.5E-57 T 13-09-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 PANTHER PTHR11070:SF23 498 759 8.9E-230 T 13-09-2016 THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 SUPERFAMILY SSF52980 907 1172 7.51E-64 T 13-09-2016 IPR011335 Restriction endonuclease type II-like THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 Gene3D G3DSA:1.10.486.10 568 711 9.5E-46 T 13-09-2016 THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 Pfam PF12705 PD-(D/E)XK nuclease superfamily 950 1150 1.5E-6 T 13-09-2016 THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 PANTHER PTHR11070 781 1167 8.9E-230 T 13-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 PANTHER PTHR11070 498 759 8.9E-230 T 13-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 THL1_RS00450 220a7326c0130c9ed83116205a8a32e5 1175 Pfam PF13361 UvrD-like helicase C-terminal domain 429 804 3.0E-17 T 13-09-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 THL1_RS17260 a55ddc44f42e7a1ca9c5f659e900c10b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 2.5E-41 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17260 a55ddc44f42e7a1ca9c5f659e900c10b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 2.5E-41 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17260 a55ddc44f42e7a1ca9c5f659e900c10b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 2.5E-41 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17260 a55ddc44f42e7a1ca9c5f659e900c10b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 2.5E-41 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17260 a55ddc44f42e7a1ca9c5f659e900c10b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 2.5E-41 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17260 a55ddc44f42e7a1ca9c5f659e900c10b 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 2.5E-41 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17260 a55ddc44f42e7a1ca9c5f659e900c10b 260 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 14 194 2.7E-5 T 13-09-2016 THL1_RS17260 a55ddc44f42e7a1ca9c5f659e900c10b 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 2.5E-14 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17260 a55ddc44f42e7a1ca9c5f659e900c10b 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 2.5E-14 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17260 a55ddc44f42e7a1ca9c5f659e900c10b 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 2.5E-14 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17260 a55ddc44f42e7a1ca9c5f659e900c10b 260 SUPERFAMILY SSF51735 9 257 2.89E-83 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS17260 a55ddc44f42e7a1ca9c5f659e900c10b 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 254 4.7E-66 T 13-09-2016 THL1_RS17260 a55ddc44f42e7a1ca9c5f659e900c10b 260 PANTHER PTHR24322 163 195 4.6E-59 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17260 a55ddc44f42e7a1ca9c5f659e900c10b 260 PANTHER PTHR24322 18 147 4.6E-59 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS17260 a55ddc44f42e7a1ca9c5f659e900c10b 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS17260 a55ddc44f42e7a1ca9c5f659e900c10b 260 Gene3D G3DSA:3.40.50.720 9 257 7.5E-87 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS22660 37bf4db7716c7063429cc5701453152f 115 PANTHER PTHR30041:SF3 1 115 1.8E-44 T 13-09-2016 THL1_RS22660 37bf4db7716c7063429cc5701453152f 115 Pfam PF03960 ArsC family 8 111 2.8E-17 T 13-09-2016 IPR006660 Arsenate reductase-like THL1_RS22660 37bf4db7716c7063429cc5701453152f 115 Gene3D G3DSA:3.40.30.10 2 114 1.1E-43 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS22660 37bf4db7716c7063429cc5701453152f 115 SUPERFAMILY SSF52833 2 114 5.38E-36 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS22660 37bf4db7716c7063429cc5701453152f 115 PANTHER PTHR30041 1 115 1.8E-44 T 13-09-2016 THL1_RS22660 37bf4db7716c7063429cc5701453152f 115 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 111 9.6E-30 T 13-09-2016 IPR006504 Transcriptional regulator Spx/MgsR THL1_RS27990 84fd1430da45eead1c70d555f6f6cecd 229 PANTHER PTHR26402:SF576 4 225 4.6E-143 T 13-09-2016 THL1_RS27990 84fd1430da45eead1c70d555f6f6cecd 229 Gene3D G3DSA:1.10.10.10 128 227 2.2E-32 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS27990 84fd1430da45eead1c70d555f6f6cecd 229 SMART SM00862 151 225 6.4E-24 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS27990 84fd1430da45eead1c70d555f6f6cecd 229 SUPERFAMILY SSF52172 3 183 1.71E-44 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS27990 84fd1430da45eead1c70d555f6f6cecd 229 Pfam PF00072 Response regulator receiver domain 6 117 6.2E-31 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS27990 84fd1430da45eead1c70d555f6f6cecd 229 PANTHER PTHR26402 4 225 4.6E-143 T 13-09-2016 THL1_RS27990 84fd1430da45eead1c70d555f6f6cecd 229 Gene3D G3DSA:3.40.50.2300 4 124 6.1E-43 T 13-09-2016 THL1_RS27990 84fd1430da45eead1c70d555f6f6cecd 229 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 3 226 2.8E-109 T 13-09-2016 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 THL1_RS27990 84fd1430da45eead1c70d555f6f6cecd 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 2.4E-24 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS27990 84fd1430da45eead1c70d555f6f6cecd 229 SMART SM00448 4 117 8.8E-46 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS08755 ed688bf961b6b1291bbdf1454eba3ef9 509 Pfam PF00069 Protein kinase domain 13 252 1.6E-48 T 13-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THL1_RS08755 ed688bf961b6b1291bbdf1454eba3ef9 509 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 127 139 - T 13-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 THL1_RS08755 ed688bf961b6b1291bbdf1454eba3ef9 509 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 13-09-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 THL1_RS08755 ed688bf961b6b1291bbdf1454eba3ef9 509 Gene3D G3DSA:3.30.200.20 11 116 3.4E-28 T 13-09-2016 THL1_RS08755 ed688bf961b6b1291bbdf1454eba3ef9 509 Gene3D G3DSA:1.10.510.10 117 261 1.9E-42 T 13-09-2016 THL1_RS08755 ed688bf961b6b1291bbdf1454eba3ef9 509 PANTHER PTHR24362 481 500 9.3E-90 T 13-09-2016 THL1_RS08755 ed688bf961b6b1291bbdf1454eba3ef9 509 SUPERFAMILY SSF48452 324 480 1.96E-5 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS08755 ed688bf961b6b1291bbdf1454eba3ef9 509 SUPERFAMILY SSF56112 8 258 3.51E-71 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS08755 ed688bf961b6b1291bbdf1454eba3ef9 509 PANTHER PTHR24362:SF160 8 288 9.3E-90 T 13-09-2016 THL1_RS08755 ed688bf961b6b1291bbdf1454eba3ef9 509 PANTHER PTHR24362:SF160 481 500 9.3E-90 T 13-09-2016 THL1_RS08755 ed688bf961b6b1291bbdf1454eba3ef9 509 PANTHER PTHR24362 8 288 9.3E-90 T 13-09-2016 THL1_RS08755 ed688bf961b6b1291bbdf1454eba3ef9 509 SMART SM00220 11 262 5.4E-59 T 13-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THL1_RS24955 0ce4dbd32872c00b51caa531e3e4936f 194 Gene3D G3DSA:3.30.70.240 127 192 2.9E-13 T 13-09-2016 IPR000640 Translation elongation factor EFG, V domain THL1_RS24955 0ce4dbd32872c00b51caa531e3e4936f 194 PANTHER PTHR16301 3 194 1.6E-52 T 13-09-2016 IPR023582 Impact family THL1_RS24955 0ce4dbd32872c00b51caa531e3e4936f 194 Pfam PF01205 Uncharacterized protein family UPF0029 16 116 1.8E-27 T 13-09-2016 IPR001498 Impact, N-terminal THL1_RS24955 0ce4dbd32872c00b51caa531e3e4936f 194 Gene3D G3DSA:3.30.230.30 4 123 5.5E-44 T 13-09-2016 IPR001498 Impact, N-terminal THL1_RS24955 0ce4dbd32872c00b51caa531e3e4936f 194 Pfam PF09186 Domain of unknown function (DUF1949) 136 188 7.9E-10 T 13-09-2016 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal THL1_RS24955 0ce4dbd32872c00b51caa531e3e4936f 194 SUPERFAMILY SSF54211 4 122 1.33E-38 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS24955 0ce4dbd32872c00b51caa531e3e4936f 194 SUPERFAMILY SSF54980 127 192 1.29E-9 T 13-09-2016 IPR009022 Elongation factor G, III-V domain THL1_RS05205 39eae38525905871eddfa2e90c280624 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 298 2.6E-18 T 13-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THL1_RS05205 39eae38525905871eddfa2e90c280624 323 Gene3D G3DSA:3.40.50.300 4 255 5.7E-77 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05205 39eae38525905871eddfa2e90c280624 323 PANTHER PTHR24220 6 322 1.4E-184 T 13-09-2016 THL1_RS05205 39eae38525905871eddfa2e90c280624 323 Pfam PF00005 ABC transporter 30 182 5.3E-34 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS05205 39eae38525905871eddfa2e90c280624 323 SUPERFAMILY SSF52540 5 253 2.35E-70 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05205 39eae38525905871eddfa2e90c280624 323 SMART SM00382 39 231 1.0E-15 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS05205 39eae38525905871eddfa2e90c280624 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 316 1.0E-25 T 13-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THL1_RS05205 39eae38525905871eddfa2e90c280624 323 PANTHER PTHR24220:SF493 6 322 1.4E-184 T 13-09-2016 THL1_RS05205 39eae38525905871eddfa2e90c280624 323 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS06705 1f15bd73bbfc9ce493618fe46049e3e8 187 PIRSF PIRSF000239 1 187 2.1E-55 T 13-09-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 THL1_RS06705 1f15bd73bbfc9ce493618fe46049e3e8 187 PANTHER PTHR10681 1 187 7.8E-92 T 13-09-2016 THL1_RS06705 1f15bd73bbfc9ce493618fe46049e3e8 187 Pfam PF00578 AhpC/TSA family 5 132 3.2E-34 T 13-09-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS06705 1f15bd73bbfc9ce493618fe46049e3e8 187 Gene3D G3DSA:3.40.30.10 4 183 3.7E-65 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS06705 1f15bd73bbfc9ce493618fe46049e3e8 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 5.3E-105 T 13-09-2016 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS06705 1f15bd73bbfc9ce493618fe46049e3e8 187 SUPERFAMILY SSF52833 1 186 3.37E-58 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS06705 1f15bd73bbfc9ce493618fe46049e3e8 187 PANTHER PTHR10681:SF121 1 187 7.8E-92 T 13-09-2016 THL1_RS06705 1f15bd73bbfc9ce493618fe46049e3e8 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 181 2.0E-6 T 13-09-2016 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS13940 0407429b37ff62174ddcf09ea65b8a04 350 Gene3D G3DSA:2.130.10.10 48 317 1.5E-37 T 13-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THL1_RS13940 0407429b37ff62174ddcf09ea65b8a04 350 SUPERFAMILY SSF110296 47 122 1.19E-45 T 13-09-2016 THL1_RS13940 0407429b37ff62174ddcf09ea65b8a04 350 SUPERFAMILY SSF110296 154 318 1.19E-45 T 13-09-2016 THL1_RS13940 0407429b37ff62174ddcf09ea65b8a04 350 Pfam PF14870 Photosynthesis system II assembly factor YCF48 150 290 2.3E-16 T 13-09-2016 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain THL1_RS13940 0407429b37ff62174ddcf09ea65b8a04 350 Pfam PF14870 Photosynthesis system II assembly factor YCF48 35 114 4.4E-9 T 13-09-2016 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain THL1_RS15750 c5617f85186db6815ded938970654f8a 253 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 14 253 1.1E-84 T 13-09-2016 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 UniPathway: UPA00930 THL1_RS15750 c5617f85186db6815ded938970654f8a 253 PANTHER PTHR30458 3 253 2.6E-99 T 13-09-2016 THL1_RS15750 c5617f85186db6815ded938970654f8a 253 PANTHER PTHR30458:SF1 3 253 2.6E-99 T 13-09-2016 THL1_RS15750 c5617f85186db6815ded938970654f8a 253 SUPERFAMILY SSF47240 4 247 4.62E-81 T 13-09-2016 IPR009078 Ferritin-like superfamily THL1_RS15750 c5617f85186db6815ded938970654f8a 253 PIRSF PIRSF037834 1 253 2.8E-97 T 13-09-2016 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 UniPathway: UPA00930 THL1_RS15750 c5617f85186db6815ded938970654f8a 253 Pfam PF05138 Phenylacetic acid catabolic protein 3 253 9.1E-94 T 13-09-2016 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 UniPathway: UPA00930 THL1_RS15750 c5617f85186db6815ded938970654f8a 253 Gene3D G3DSA:1.20.1260.10 3 253 1.0E-93 T 13-09-2016 IPR012347 Ferritin-related THL1_RS03345 6f822cd087eae35923855e65a398763d 493 SUPERFAMILY SSF52540 231 450 1.74E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03345 6f822cd087eae35923855e65a398763d 493 SMART SM00382 265 398 2.3E-9 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS03345 6f822cd087eae35923855e65a398763d 493 Gene3D G3DSA:3.40.50.300 258 435 3.2E-42 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03345 6f822cd087eae35923855e65a398763d 493 PANTHER PTHR23077:SF75 201 492 2.2E-122 T 13-09-2016 THL1_RS03345 6f822cd087eae35923855e65a398763d 493 SUPERFAMILY SSF52540 82 214 4.47E-5 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03345 6f822cd087eae35923855e65a398763d 493 PANTHER PTHR23077 201 492 2.2E-122 T 13-09-2016 THL1_RS03345 6f822cd087eae35923855e65a398763d 493 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 269 395 5.6E-27 T 13-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 THL1_RS27580 ffe26b934520f6e53d265c6018e3ab50 222 PANTHER PTHR11260:SF253 2 199 7.9E-63 T 13-09-2016 THL1_RS27580 ffe26b934520f6e53d265c6018e3ab50 222 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 72 6.4E-15 T 13-09-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THL1_RS27580 ffe26b934520f6e53d265c6018e3ab50 222 SUPERFAMILY SSF47616 90 203 9.33E-20 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS27580 ffe26b934520f6e53d265c6018e3ab50 222 Gene3D G3DSA:3.40.30.10 2 80 2.7E-22 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS27580 ffe26b934520f6e53d265c6018e3ab50 222 Gene3D G3DSA:1.20.1050.10 88 200 1.9E-17 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS27580 ffe26b934520f6e53d265c6018e3ab50 222 PANTHER PTHR11260 2 199 7.9E-63 T 13-09-2016 THL1_RS27580 ffe26b934520f6e53d265c6018e3ab50 222 SUPERFAMILY SSF52833 1 80 4.31E-20 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 PANTHER PTHR24423:SF450 465 672 1.4E-150 T 13-09-2016 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 PANTHER PTHR24423:SF450 286 441 1.4E-150 T 13-09-2016 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 593 607 8.4E-17 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 649 662 8.4E-17 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 611 621 8.4E-17 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 PRINTS PR00344 Bacterial sensor protein C-terminal signature 624 642 8.4E-17 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 Gene3D G3DSA:3.30.565.10 489 665 2.3E-41 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 SUPERFAMILY SSF55785 276 396 6.81E-12 T 13-09-2016 IPR000014 PAS domain THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 289 403 3.6E-6 T 13-09-2016 IPR000014 PAS domain THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 SMART SM00304 186 239 2.3E-9 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 Pfam PF00672 HAMP domain 166 235 2.9E-12 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 SUPERFAMILY SSF55874 494 664 4.45E-37 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 Pfam PF08448 PAS fold 295 398 2.7E-7 T 13-09-2016 IPR013656 PAS fold-4 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 PANTHER PTHR24423 465 672 1.4E-150 T 13-09-2016 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 PANTHER PTHR24423 286 441 1.4E-150 T 13-09-2016 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 Gene3D G3DSA:1.10.287.130 415 488 8.3E-7 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 554 664 2.5E-23 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 SUPERFAMILY SSF47384 409 503 4.71E-8 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 PANTHER PTHR24423:SF450 230 249 1.4E-150 T 13-09-2016 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 PANTHER PTHR24423:SF450 95 162 1.4E-150 T 13-09-2016 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 SUPERFAMILY SSF158472 186 235 1.24E-7 T 13-09-2016 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 Pfam PF00512 His Kinase A (phospho-acceptor) domain 415 501 2.0E-10 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 PANTHER PTHR24423 95 162 1.4E-150 T 13-09-2016 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 SMART SM00387 551 665 6.7E-30 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 SMART SM00388 413 503 2.1E-6 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 Gene3D G3DSA:3.30.450.20 287 396 1.2E-12 T 13-09-2016 THL1_RS05715 563617dd5440edcbb86ded74285522e3 672 PANTHER PTHR24423 230 249 1.4E-150 T 13-09-2016 THL1_RS09155 1f63135c7e6649e71d974c7cbebcca50 124 SMART SM00507 28 83 3.5E-6 T 13-09-2016 IPR003615 HNH nuclease THL1_RS09155 1f63135c7e6649e71d974c7cbebcca50 124 Gene3D G3DSA:3.30.160.60 37 62 9.2E-4 T 13-09-2016 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 THL1_RS09155 1f63135c7e6649e71d974c7cbebcca50 124 Pfam PF01844 HNH endonuclease 40 88 9.5E-13 T 13-09-2016 IPR002711 HNH endonuclease GO:0003676|GO:0004519 THL1_RS22720 a8fd4c5538159c2e0381bc7c3bc2cee4 611 Gene3D G3DSA:3.40.30.10 43 124 2.6E-4 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS22720 a8fd4c5538159c2e0381bc7c3bc2cee4 611 Pfam PF09822 ABC-type uncharacterized transport system 33 300 1.6E-69 T 13-09-2016 IPR019196 ABC-type uncharacterised transport system THL1_RS07165 b1c117daa0a575ed9ba52f7ce852d19b 344 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 6 339 4.0E-166 T 13-09-2016 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 THL1_RS07165 b1c117daa0a575ed9ba52f7ce852d19b 344 PANTHER PTHR10277 1 265 4.8E-95 T 13-09-2016 THL1_RS07165 b1c117daa0a575ed9ba52f7ce852d19b 344 SUPERFAMILY SSF51569 4 277 2.75E-68 T 13-09-2016 THL1_RS07165 b1c117daa0a575ed9ba52f7ce852d19b 344 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 344 202.055 T 13-09-2016 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 THL1_RS07165 b1c117daa0a575ed9ba52f7ce852d19b 344 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 274 338 2.0E-26 T 13-09-2016 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 THL1_RS07165 b1c117daa0a575ed9ba52f7ce852d19b 344 Pfam PF00682 HMGL-like 8 264 8.4E-60 T 13-09-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 THL1_RS07165 b1c117daa0a575ed9ba52f7ce852d19b 344 Pfam PF07836 DmpG-like communication domain 276 337 1.9E-29 T 13-09-2016 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 THL1_RS07165 b1c117daa0a575ed9ba52f7ce852d19b 344 SUPERFAMILY SSF89000 290 339 8.24E-16 T 13-09-2016 THL1_RS07165 b1c117daa0a575ed9ba52f7ce852d19b 344 Gene3D G3DSA:1.10.8.60 277 340 2.8E-32 T 13-09-2016 THL1_RS07165 b1c117daa0a575ed9ba52f7ce852d19b 344 Gene3D G3DSA:3.20.20.70 6 264 6.9E-57 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS07165 b1c117daa0a575ed9ba52f7ce852d19b 344 PANTHER PTHR10277:SF3 1 265 4.8E-95 T 13-09-2016 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 Hamap MF_01201 Alanine racemase. 43 410 24.927 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 SUPERFAMILY SSF51419 50 272 5.05E-45 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 SMART SM01005 282 410 1.1E-48 T 13-09-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 TIGRFAM TIGR00492 alr: alanine racemase 46 387 1.1E-69 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 PANTHER PTHR30511 40 412 1.7E-115 T 13-09-2016 THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 Gene3D G3DSA:3.20.20.10 54 265 1.7E-47 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 Gene3D G3DSA:2.40.37.10 266 409 2.4E-45 T 13-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 PRINTS PR00992 Alanine racemase signature 105 123 1.3E-34 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 PRINTS PR00992 Alanine racemase signature 203 214 1.3E-34 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 PRINTS PR00992 Alanine racemase signature 298 313 1.3E-34 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 PRINTS PR00992 Alanine racemase signature 315 330 1.3E-34 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 PRINTS PR00992 Alanine racemase signature 336 353 1.3E-34 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 PRINTS PR00992 Alanine racemase signature 246 273 1.3E-34 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 PRINTS PR00992 Alanine racemase signature 69 85 1.3E-34 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 PRINTS PR00992 Alanine racemase signature 167 179 1.3E-34 T 13-09-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 PANTHER PTHR30511:SF0 40 412 1.7E-115 T 13-09-2016 THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 SUPERFAMILY SSF50621 278 409 5.23E-40 T 13-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 Pfam PF01168 Alanine racemase, N-terminal domain 50 271 9.5E-48 T 13-09-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS14775 5813a0d911f0918571ea42727334ce24 412 Pfam PF00842 Alanine racemase, C-terminal domain 282 384 7.7E-29 T 13-09-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 THL1_RS19465 4751292475cb614687292f34887903b4 159 Gene3D G3DSA:2.30.30.40 90 141 4.4E-8 T 13-09-2016 THL1_RS19465 4751292475cb614687292f34887903b4 159 Gene3D G3DSA:2.40.50.180 54 89 9.2E-10 T 13-09-2016 THL1_RS19465 4751292475cb614687292f34887903b4 159 PANTHER PTHR22617 9 159 1.4E-111 T 13-09-2016 THL1_RS19465 4751292475cb614687292f34887903b4 159 PANTHER PTHR22617:SF26 9 159 1.4E-111 T 13-09-2016 THL1_RS19465 4751292475cb614687292f34887903b4 159 Pfam PF01584 CheW-like domain 15 151 2.0E-40 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS19465 4751292475cb614687292f34887903b4 159 SUPERFAMILY SSF50341 12 154 7.19E-43 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS19465 4751292475cb614687292f34887903b4 159 SMART SM00260 11 148 5.4E-54 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS27795 e2125f5bd8897fe4612a5fe5f299be5a 446 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 256 293 - T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS27795 e2125f5bd8897fe4612a5fe5f299be5a 446 Pfam PF00202 Aminotransferase class-III 25 440 2.1E-113 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS27795 e2125f5bd8897fe4612a5fe5f299be5a 446 SUPERFAMILY SSF53383 19 443 2.0E-122 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS27795 e2125f5bd8897fe4612a5fe5f299be5a 446 PANTHER PTHR11986 11 444 4.0E-299 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS27795 e2125f5bd8897fe4612a5fe5f299be5a 446 Gene3D G3DSA:3.40.640.10 70 344 3.9E-88 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS27795 e2125f5bd8897fe4612a5fe5f299be5a 446 PANTHER PTHR11986:SF80 11 444 4.0E-299 T 13-09-2016 THL1_RS27795 e2125f5bd8897fe4612a5fe5f299be5a 446 Gene3D G3DSA:3.90.1150.10 348 444 1.2E-40 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS27795 e2125f5bd8897fe4612a5fe5f299be5a 446 Gene3D G3DSA:3.90.1150.10 17 68 1.2E-40 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS18735 a2b63fe00e2a39230d2ac617ee196d5a 79 Pfam PF01206 Sulfurtransferase TusA 8 76 1.1E-23 T 13-09-2016 IPR001455 TusA-like domain THL1_RS18735 a2b63fe00e2a39230d2ac617ee196d5a 79 PANTHER PTHR33279:SF5 5 76 8.2E-37 T 13-09-2016 THL1_RS18735 a2b63fe00e2a39230d2ac617ee196d5a 79 PANTHER PTHR33279 5 76 8.2E-37 T 13-09-2016 THL1_RS18735 a2b63fe00e2a39230d2ac617ee196d5a 79 SUPERFAMILY SSF64307 3 76 3.53E-25 T 13-09-2016 IPR001455 TusA-like domain THL1_RS18735 a2b63fe00e2a39230d2ac617ee196d5a 79 Gene3D G3DSA:3.30.110.40 2 77 5.4E-29 T 13-09-2016 IPR001455 TusA-like domain THL1_RS18735 a2b63fe00e2a39230d2ac617ee196d5a 79 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 9 33 - T 13-09-2016 IPR001455 TusA-like domain THL1_RS18735 a2b63fe00e2a39230d2ac617ee196d5a 79 Hamap MF_00413 Sulfurtransferase TusA [tusA]. 1 78 24.664 T 13-09-2016 IPR022931 Sulphurtransferase TusA GO:0016783 THL1_RS11850 85d3ec9d078b029e109e3650c6889a35 449 PANTHER PTHR11236 9 445 4.0E-156 T 13-09-2016 THL1_RS11850 85d3ec9d078b029e109e3650c6889a35 449 Pfam PF00425 chorismate binding enzyme 182 436 3.4E-97 T 13-09-2016 IPR015890 Chorismate-utilising enzyme, C-terminal THL1_RS11850 85d3ec9d078b029e109e3650c6889a35 449 Gene3D G3DSA:3.60.120.10 7 445 1.4E-146 T 13-09-2016 IPR005801 ADC synthase GO:0009058 THL1_RS11850 85d3ec9d078b029e109e3650c6889a35 449 Pfam PF04715 Anthranilate synthase component I, N terminal region 13 138 1.1E-18 T 13-09-2016 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 THL1_RS11850 85d3ec9d078b029e109e3650c6889a35 449 PRINTS PR00095 Anthranilate synthase component I signature 393 407 2.0E-15 T 13-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 THL1_RS11850 85d3ec9d078b029e109e3650c6889a35 449 PRINTS PR00095 Anthranilate synthase component I signature 298 311 2.0E-15 T 13-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 THL1_RS11850 85d3ec9d078b029e109e3650c6889a35 449 PRINTS PR00095 Anthranilate synthase component I signature 284 297 2.0E-15 T 13-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 THL1_RS11850 85d3ec9d078b029e109e3650c6889a35 449 PRINTS PR00095 Anthranilate synthase component I signature 378 392 2.0E-15 T 13-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 THL1_RS11850 85d3ec9d078b029e109e3650c6889a35 449 SUPERFAMILY SSF56322 6 445 5.63E-138 T 13-09-2016 IPR005801 ADC synthase GO:0009058 THL1_RS11850 85d3ec9d078b029e109e3650c6889a35 449 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 93 440 1.7E-112 T 13-09-2016 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543|UniPathway: UPA00077 THL1_RS25360 1f46ac51ce8458fbe444ba7419d813c3 137 SMART SM00448 9 123 1.2E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS25360 1f46ac51ce8458fbe444ba7419d813c3 137 Gene3D G3DSA:3.40.50.2300 9 128 9.6E-30 T 13-09-2016 THL1_RS25360 1f46ac51ce8458fbe444ba7419d813c3 137 PANTHER PTHR26402 9 124 6.6E-26 T 13-09-2016 THL1_RS25360 1f46ac51ce8458fbe444ba7419d813c3 137 Pfam PF00072 Response regulator receiver domain 12 123 5.1E-22 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS25360 1f46ac51ce8458fbe444ba7419d813c3 137 SUPERFAMILY SSF52172 11 128 7.26E-31 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 SUPERFAMILY SSF51735 1 113 1.32E-26 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 216 451 2.9E-95 T 13-09-2016 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 218 427 5.7E-55 T 13-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 Gene3D G3DSA:3.30.950.10 332 459 3.9E-52 T 13-09-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 PANTHER PTHR21091 165 454 1.9E-85 T 13-09-2016 THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 Pfam PF14824 Sirohaem biosynthesis protein central 119 144 1.4E-6 T 13-09-2016 IPR028281 Siroheme synthase, central domain KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 296 329 - T 13-09-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 Gene3D G3DSA:3.40.1010.10 216 331 5.5E-48 T 13-09-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 Gene3D G3DSA:1.10.8.210 150 208 3.9E-22 T 13-09-2016 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 Hamap MF_01646 Siroheme synthase [cysG]. 1 460 53.78 T 13-09-2016 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 PIRSF PIRSF036426 1 464 3.1E-207 T 13-09-2016 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 Pfam PF10414 Sirohaem synthase dimerisation region 150 205 7.6E-21 T 13-09-2016 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 Gene3D G3DSA:3.40.50.720 1 113 2.7E-35 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 SUPERFAMILY SSF53790 215 459 1.57E-84 T 13-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 Pfam PF13241 Putative NAD(P)-binding 6 115 2.0E-29 T 13-09-2016 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 207 1.6E-80 T 13-09-2016 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 Gene3D G3DSA:3.30.160.110 114 148 1.1E-17 T 13-09-2016 THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 PANTHER PTHR21091:SF16 165 454 1.9E-85 T 13-09-2016 THL1_RS12430 34f5e65a32af3f6cd0a33794cc55ed63 464 SUPERFAMILY SSF75615 114 209 4.71E-27 T 13-09-2016 THL1_RS06000 c63f90222507da807cb9c61c1a4857a0 380 SMART SM00564 187 218 39.0 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS06000 c63f90222507da807cb9c61c1a4857a0 380 SMART SM00564 276 307 570.0 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS06000 c63f90222507da807cb9c61c1a4857a0 380 SMART SM00564 237 269 0.18 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS06000 c63f90222507da807cb9c61c1a4857a0 380 SMART SM00564 317 348 460.0 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS06000 c63f90222507da807cb9c61c1a4857a0 380 SMART SM00564 142 173 0.74 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS06000 c63f90222507da807cb9c61c1a4857a0 380 SMART SM00564 62 93 4.0E-5 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS06000 c63f90222507da807cb9c61c1a4857a0 380 SMART SM00564 101 133 0.014 T 13-09-2016 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THL1_RS06000 c63f90222507da807cb9c61c1a4857a0 380 Pfam PF13360 PQQ-like domain 75 305 2.9E-47 T 13-09-2016 IPR002372 Pyrrolo-quinoline quinone repeat THL1_RS06000 c63f90222507da807cb9c61c1a4857a0 380 PANTHER PTHR32303:SF8 29 366 4.5E-75 T 13-09-2016 THL1_RS06000 c63f90222507da807cb9c61c1a4857a0 380 PANTHER PTHR32303 29 366 4.5E-75 T 13-09-2016 THL1_RS06000 c63f90222507da807cb9c61c1a4857a0 380 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 6 377 2.2E-133 T 13-09-2016 IPR017687 Outer membrane protein assembly factor BamB THL1_RS06000 c63f90222507da807cb9c61c1a4857a0 380 SUPERFAMILY SSF50998 29 367 2.55E-78 T 13-09-2016 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THL1_RS06000 c63f90222507da807cb9c61c1a4857a0 380 Gene3D G3DSA:2.140.10.10 7 378 1.2E-66 T 13-09-2016 IPR027295 Quinoprotein alcohol dehydrogenase-like domain THL1_RS06000 c63f90222507da807cb9c61c1a4857a0 380 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 1 379 38.477 T 13-09-2016 IPR017687 Outer membrane protein assembly factor BamB THL1_RS17330 ac5c788f9989b9e3557b9a8c11db9ffe 329 Pfam PF03524 Conjugal transfer protein 102 321 8.7E-66 T 13-09-2016 IPR010258 Conjugal transfer, TrbG/VirB9/CagX THL1_RS17330 ac5c788f9989b9e3557b9a8c11db9ffe 329 TIGRFAM TIGR02775 TrbG_Ti: P-type conjugative transfer protein TrbG 103 310 3.1E-87 T 13-09-2016 IPR014142 P-type conjugative transfer protein TrbG THL1_RS07920 2084c71260217e4807b39e961967109b 247 SUPERFAMILY SSF53850 1 245 6.65E-75 T 13-09-2016 THL1_RS07920 2084c71260217e4807b39e961967109b 247 Gene3D G3DSA:3.40.190.10 207 245 1.9E-44 T 13-09-2016 THL1_RS07920 2084c71260217e4807b39e961967109b 247 Gene3D G3DSA:3.40.190.10 24 102 1.9E-44 T 13-09-2016 THL1_RS07920 2084c71260217e4807b39e961967109b 247 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 48 61 - T 13-09-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 THL1_RS07920 2084c71260217e4807b39e961967109b 247 PANTHER PTHR18966 25 247 3.5E-59 T 13-09-2016 THL1_RS07920 2084c71260217e4807b39e961967109b 247 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 243 7.8E-69 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS07920 2084c71260217e4807b39e961967109b 247 SMART SM00062 26 245 1.7E-71 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS07920 2084c71260217e4807b39e961967109b 247 SMART SM00079 26 244 1.3E-6 T 13-09-2016 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 THL1_RS07920 2084c71260217e4807b39e961967109b 247 Gene3D G3DSA:3.40.190.10 103 206 2.3E-30 T 13-09-2016 THL1_RS09695 526fc4cabbd6fe9d537acfe9dea3f64d 441 Gene3D G3DSA:1.20.1250.20 246 429 1.7E-15 T 13-09-2016 THL1_RS09695 526fc4cabbd6fe9d537acfe9dea3f64d 441 Gene3D G3DSA:1.20.1250.20 19 217 6.0E-44 T 13-09-2016 THL1_RS09695 526fc4cabbd6fe9d537acfe9dea3f64d 441 PANTHER PTHR11662:SF3 13 434 2.3E-151 T 13-09-2016 THL1_RS09695 526fc4cabbd6fe9d537acfe9dea3f64d 441 SUPERFAMILY SSF103473 17 425 2.49E-78 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS09695 526fc4cabbd6fe9d537acfe9dea3f64d 441 Pfam PF07690 Major Facilitator Superfamily 26 390 1.1E-44 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS09695 526fc4cabbd6fe9d537acfe9dea3f64d 441 PANTHER PTHR11662 13 434 2.3E-151 T 13-09-2016 THL1_RS22250 ebc49215b271530b66496c5a1b094d72 182 PANTHER PTHR14269 4 179 6.9E-27 T 13-09-2016 THL1_RS22250 ebc49215b271530b66496c5a1b094d72 182 PIRSF PIRSF000847 1 182 8.0E-46 T 13-09-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 THL1_RS22250 ebc49215b271530b66496c5a1b094d72 182 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 67 3.9E-14 T 13-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THL1_RS22250 ebc49215b271530b66496c5a1b094d72 182 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 45 67 - T 13-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THL1_RS24175 40c5bd7ba3cd318d72c19bddd4fc786d 271 PANTHER PTHR15362 31 173 9.7E-38 T 13-09-2016 THL1_RS24175 40c5bd7ba3cd318d72c19bddd4fc786d 271 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 48 210 6.8E-38 T 13-09-2016 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 THL1_RS24175 40c5bd7ba3cd318d72c19bddd4fc786d 271 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 84 106 - T 13-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THL1_RS24175 40c5bd7ba3cd318d72c19bddd4fc786d 271 Pfam PF01066 CDP-alcohol phosphatidyltransferase 43 106 6.0E-14 T 13-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THL1_RS05000 7469b8b8aee003332f4a81d2ea749b87 113 Pfam PF07238 PilZ domain 3 107 4.2E-9 T 13-09-2016 IPR009875 PilZ domain GO:0035438 THL1_RS05000 7469b8b8aee003332f4a81d2ea749b87 113 SUPERFAMILY SSF141371 1 110 2.51E-9 T 13-09-2016 THL1_RS22360 81131139373f8a9e2915132d3b3f89ee 423 Gene3D G3DSA:3.40.50.1820 267 334 9.1E-11 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS22360 81131139373f8a9e2915132d3b3f89ee 423 Gene3D G3DSA:3.40.50.1820 93 188 7.2E-5 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS22360 81131139373f8a9e2915132d3b3f89ee 423 SUPERFAMILY SSF53474 216 381 2.79E-22 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS22360 81131139373f8a9e2915132d3b3f89ee 423 Pfam PF06057 Bacterial virulence protein (VirJ) 229 416 2.6E-73 T 13-09-2016 IPR010333 Bacterial virulence THL1_RS22360 81131139373f8a9e2915132d3b3f89ee 423 PIRSF PIRSF029063 1 421 1.7E-123 T 13-09-2016 IPR011225 Type IV secretory pathway, VirJ component THL1_RS27190 291cc5df945f5422ccdc99a0ae785742 594 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 22 168 8.6E-16 T 13-09-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 THL1_RS27190 291cc5df945f5422ccdc99a0ae785742 594 Pfam PF00437 Type II/IV secretion system protein 220 480 8.9E-75 T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS27190 291cc5df945f5422ccdc99a0ae785742 594 Gene3D G3DSA:3.40.50.300 319 591 4.8E-94 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27190 291cc5df945f5422ccdc99a0ae785742 594 SUPERFAMILY SSF160246 16 164 2.25E-11 T 13-09-2016 THL1_RS27190 291cc5df945f5422ccdc99a0ae785742 594 PANTHER PTHR30258:SF13 1 594 0.0 T 13-09-2016 THL1_RS27190 291cc5df945f5422ccdc99a0ae785742 594 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 408 422 - T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS27190 291cc5df945f5422ccdc99a0ae785742 594 PANTHER PTHR30258 1 594 0.0 T 13-09-2016 THL1_RS27190 291cc5df945f5422ccdc99a0ae785742 594 SUPERFAMILY SSF52540 192 588 3.3E-100 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27190 291cc5df945f5422ccdc99a0ae785742 594 Gene3D G3DSA:3.30.450.90 195 313 3.2E-46 T 13-09-2016 THL1_RS27190 291cc5df945f5422ccdc99a0ae785742 594 SMART SM00382 341 464 7.7E-5 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS22305 cfb99550639a3912ff0677405485cebd 226 SMART SM00702 1 177 1.1E-26 T 13-09-2016 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 THL1_RS22305 cfb99550639a3912ff0677405485cebd 226 PANTHER PTHR41536 2 226 1.0E-125 T 13-09-2016 THL1_RS22305 cfb99550639a3912ff0677405485cebd 226 SUPERFAMILY SSF51197 3 177 3.85E-7 T 13-09-2016 THL1_RS22305 cfb99550639a3912ff0677405485cebd 226 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 84 176 4.5E-13 T 13-09-2016 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 THL1_RS22305 cfb99550639a3912ff0677405485cebd 226 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 226 46.374 T 13-09-2016 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 THL1_RS22305 cfb99550639a3912ff0677405485cebd 226 PANTHER PTHR41536:SF1 2 226 1.0E-125 T 13-09-2016 THL1_RS17195 b695150f9f203cd7b1060f25972a2a42 427 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 289 411 1.2E-24 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS17195 b695150f9f203cd7b1060f25972a2a42 427 PANTHER PTHR10909:SF121 18 156 1.5E-52 T 13-09-2016 THL1_RS17195 b695150f9f203cd7b1060f25972a2a42 427 SUPERFAMILY SSF56645 21 264 3.01E-25 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS17195 b695150f9f203cd7b1060f25972a2a42 427 PANTHER PTHR10909 172 410 1.5E-52 T 13-09-2016 THL1_RS17195 b695150f9f203cd7b1060f25972a2a42 427 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 138 255 1.4E-8 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS17195 b695150f9f203cd7b1060f25972a2a42 427 Gene3D G3DSA:1.20.140.10 255 414 1.0E-34 T 13-09-2016 THL1_RS17195 b695150f9f203cd7b1060f25972a2a42 427 PANTHER PTHR10909:SF121 172 410 1.5E-52 T 13-09-2016 THL1_RS17195 b695150f9f203cd7b1060f25972a2a42 427 Gene3D G3DSA:1.10.540.10 16 130 7.9E-10 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS17195 b695150f9f203cd7b1060f25972a2a42 427 PANTHER PTHR10909 18 156 1.5E-52 T 13-09-2016 THL1_RS17195 b695150f9f203cd7b1060f25972a2a42 427 Gene3D G3DSA:2.40.110.10 137 254 6.9E-23 T 13-09-2016 THL1_RS17195 b695150f9f203cd7b1060f25972a2a42 427 SUPERFAMILY SSF47203 277 413 9.18E-32 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS07825 7cc68d9254b674bd6f061fe2ccb65997 221 SUPERFAMILY SSF161098 12 201 1.31E-36 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07825 7cc68d9254b674bd6f061fe2ccb65997 221 Gene3D G3DSA:1.10.3720.10 12 216 8.8E-37 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07825 7cc68d9254b674bd6f061fe2ccb65997 221 PANTHER PTHR30614 1 221 3.8E-73 T 13-09-2016 THL1_RS07825 7cc68d9254b674bd6f061fe2ccb65997 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 216 4.0E-16 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07825 7cc68d9254b674bd6f061fe2ccb65997 221 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 110 5.6E-26 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS11455 a7c76c0bc83cd0ba3b7a72fcb4e09f8f 154 SUPERFAMILY SSF46955 1 112 2.38E-25 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS11455 a7c76c0bc83cd0ba3b7a72fcb4e09f8f 154 Pfam PF13411 MerR HTH family regulatory protein 1 66 5.7E-15 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS11455 a7c76c0bc83cd0ba3b7a72fcb4e09f8f 154 Gene3D G3DSA:1.10.1660.10 55 116 6.7E-10 T 13-09-2016 THL1_RS11455 a7c76c0bc83cd0ba3b7a72fcb4e09f8f 154 SMART SM00422 1 69 4.8E-21 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS11455 a7c76c0bc83cd0ba3b7a72fcb4e09f8f 154 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS11455 a7c76c0bc83cd0ba3b7a72fcb4e09f8f 154 Gene3D G3DSA:1.10.1660.10 1 54 5.9E-22 T 13-09-2016 THL1_RS11455 a7c76c0bc83cd0ba3b7a72fcb4e09f8f 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.1E-6 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS11455 a7c76c0bc83cd0ba3b7a72fcb4e09f8f 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.1E-6 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS11455 a7c76c0bc83cd0ba3b7a72fcb4e09f8f 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.1E-6 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS11455 a7c76c0bc83cd0ba3b7a72fcb4e09f8f 154 PANTHER PTHR30204 1 135 4.8E-30 T 13-09-2016 THL1_RS11455 a7c76c0bc83cd0ba3b7a72fcb4e09f8f 154 PANTHER PTHR30204:SF30 1 135 4.8E-30 T 13-09-2016 THL1_RS17205 46f034cdb8469761c77fa9b77b034609 394 Gene3D G3DSA:3.40.47.10 196 276 2.1E-65 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17205 46f034cdb8469761c77fa9b77b034609 394 Gene3D G3DSA:3.40.47.10 5 126 2.1E-65 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17205 46f034cdb8469761c77fa9b77b034609 394 PIRSF PIRSF000429 1 394 1.8E-131 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS17205 46f034cdb8469761c77fa9b77b034609 394 Gene3D G3DSA:3.40.47.10 278 393 3.0E-62 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17205 46f034cdb8469761c77fa9b77b034609 394 Gene3D G3DSA:3.40.47.10 148 195 3.0E-62 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17205 46f034cdb8469761c77fa9b77b034609 394 Pfam PF02803 Thiolase, C-terminal domain 272 393 3.6E-45 T 13-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THL1_RS17205 46f034cdb8469761c77fa9b77b034609 394 SUPERFAMILY SSF53901 272 393 7.84E-44 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17205 46f034cdb8469761c77fa9b77b034609 394 PANTHER PTHR18919 1 394 1.0E-190 T 13-09-2016 THL1_RS17205 46f034cdb8469761c77fa9b77b034609 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 392 2.7E-137 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS17205 46f034cdb8469761c77fa9b77b034609 394 ProSitePatterns PS00099 Thiolases active site. 375 388 - T 13-09-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 THL1_RS17205 46f034cdb8469761c77fa9b77b034609 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 13-09-2016 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 Reactome: REACT_22258 THL1_RS17205 46f034cdb8469761c77fa9b77b034609 394 SUPERFAMILY SSF53901 5 271 2.16E-83 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17205 46f034cdb8469761c77fa9b77b034609 394 PANTHER PTHR18919:SF95 1 394 1.0E-190 T 13-09-2016 THL1_RS17205 46f034cdb8469761c77fa9b77b034609 394 Pfam PF00108 Thiolase, N-terminal domain 6 262 1.3E-87 T 13-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THL1_RS05755 1a77e18848630576f5f6592335c7aedb 332 Pfam PF04338 Protein of unknown function, DUF481 139 332 3.4E-27 T 13-09-2016 IPR007433 Protein of unknown function DUF481 THL1_RS01275 57157cb979a06e5156ba52ff18573717 206 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 2 195 3.1E-90 T 13-09-2016 IPR010743 Methionine biosynthesis MetW THL1_RS01275 57157cb979a06e5156ba52ff18573717 206 PANTHER PTHR10108:SF831 1 166 3.3E-80 T 13-09-2016 THL1_RS01275 57157cb979a06e5156ba52ff18573717 206 Pfam PF07021 Methionine biosynthesis protein MetW 2 194 8.0E-91 T 13-09-2016 IPR010743 Methionine biosynthesis MetW THL1_RS01275 57157cb979a06e5156ba52ff18573717 206 Gene3D G3DSA:3.40.50.150 12 170 3.2E-28 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS01275 57157cb979a06e5156ba52ff18573717 206 SUPERFAMILY SSF53335 3 189 1.01E-32 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS01275 57157cb979a06e5156ba52ff18573717 206 PANTHER PTHR10108 1 166 3.3E-80 T 13-09-2016 THL1_RS12405 be48c3ea5fe12eef1cb40abcedf27a86 786 SUPERFAMILY SSF46785 718 781 6.6E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12405 be48c3ea5fe12eef1cb40abcedf27a86 786 Pfam PF09397 Ftsk gamma domain 720 780 3.2E-27 T 13-09-2016 IPR018541 FtsK gamma domain THL1_RS12405 be48c3ea5fe12eef1cb40abcedf27a86 786 SMART SM00843 718 783 1.8E-38 T 13-09-2016 IPR018541 FtsK gamma domain THL1_RS12405 be48c3ea5fe12eef1cb40abcedf27a86 786 SUPERFAMILY SSF52540 371 683 1.09E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS12405 be48c3ea5fe12eef1cb40abcedf27a86 786 Pfam PF01580 FtsK/SpoIIIE family 400 610 2.8E-65 T 13-09-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 THL1_RS12405 be48c3ea5fe12eef1cb40abcedf27a86 786 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 4 174 1.4E-39 T 13-09-2016 IPR025199 DNA translocase FtsK, 4TM region THL1_RS12405 be48c3ea5fe12eef1cb40abcedf27a86 786 PANTHER PTHR22683:SF41 213 781 5.5E-274 T 13-09-2016 THL1_RS12405 be48c3ea5fe12eef1cb40abcedf27a86 786 PANTHER PTHR22683 213 781 5.5E-274 T 13-09-2016 THL1_RS12405 be48c3ea5fe12eef1cb40abcedf27a86 786 Gene3D G3DSA:3.40.50.300 372 677 1.3E-97 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07240 b8fd2631c598f5ef3b5881ab13fc39b0 302 SUPERFAMILY SSF46785 4 88 3.29E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07240 b8fd2631c598f5ef3b5881ab13fc39b0 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 5.1E-17 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS07240 b8fd2631c598f5ef3b5881ab13fc39b0 302 PANTHER PTHR30537 1 296 6.8E-156 T 13-09-2016 THL1_RS07240 b8fd2631c598f5ef3b5881ab13fc39b0 302 SUPERFAMILY SSF53850 90 299 3.44E-40 T 13-09-2016 THL1_RS07240 b8fd2631c598f5ef3b5881ab13fc39b0 302 Gene3D G3DSA:1.10.10.10 4 82 1.0E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07240 b8fd2631c598f5ef3b5881ab13fc39b0 302 Gene3D G3DSA:3.40.190.10 93 181 2.0E-19 T 13-09-2016 THL1_RS07240 b8fd2631c598f5ef3b5881ab13fc39b0 302 PANTHER PTHR30537:SF29 1 296 6.8E-156 T 13-09-2016 THL1_RS07240 b8fd2631c598f5ef3b5881ab13fc39b0 302 Gene3D G3DSA:3.40.190.10 182 264 9.3E-22 T 13-09-2016 THL1_RS07240 b8fd2631c598f5ef3b5881ab13fc39b0 302 Pfam PF03466 LysR substrate binding domain 89 296 4.9E-37 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS04975 f4c9c1f328262b61c98513bed28f0f10 339 Gene3D G3DSA:1.25.40.10 33 149 8.5E-4 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS04975 f4c9c1f328262b61c98513bed28f0f10 339 Gene3D G3DSA:1.25.40.10 207 235 8.5E-4 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS04975 f4c9c1f328262b61c98513bed28f0f10 339 SUPERFAMILY SSF48452 33 120 1.19E-5 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS04975 f4c9c1f328262b61c98513bed28f0f10 339 PANTHER PTHR37423 1 290 3.6E-108 T 13-09-2016 THL1_RS04975 f4c9c1f328262b61c98513bed28f0f10 339 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 1 242 47.486 T 13-09-2016 IPR017689 Outer membrane protein assembly factor BamD THL1_RS04975 f4c9c1f328262b61c98513bed28f0f10 339 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 5 245 3.2E-83 T 13-09-2016 IPR017689 Outer membrane protein assembly factor BamD THL1_RS04975 f4c9c1f328262b61c98513bed28f0f10 339 Pfam PF13525 Outer membrane lipoprotein 30 232 1.5E-73 T 13-09-2016 THL1_RS20665 8bc21276706b64eb3c3320cfce5b13c6 155 SUPERFAMILY SSF55811 20 143 7.58E-15 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS20665 8bc21276706b64eb3c3320cfce5b13c6 155 Pfam PF00293 NUDIX domain 22 129 1.0E-7 T 13-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 THL1_RS20665 8bc21276706b64eb3c3320cfce5b13c6 155 Gene3D G3DSA:3.90.79.10 20 146 1.3E-12 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS04615 1771749d2f2ad07dc77f21de0539b302 430 Pfam PF00860 Permease family 18 390 3.8E-54 T 13-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS04615 1771749d2f2ad07dc77f21de0539b302 430 PANTHER PTHR11119 1 418 7.8E-167 T 13-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS04615 1771749d2f2ad07dc77f21de0539b302 430 PANTHER PTHR11119:SF9 1 418 7.8E-167 T 13-09-2016 IPR029940 AzgA purine transporter GO:0005345|GO:0006863 THL1_RS04615 1771749d2f2ad07dc77f21de0539b302 430 PIRSF PIRSF005353 1 430 8.3E-177 T 13-09-2016 IPR026033 Purine permease PbuG-like THL1_RS04920 4953e32ac6b4ab9b52c868093a18a585 155 Pfam PF12019 Type II transport protein GspH 43 134 3.5E-8 T 13-09-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 THL1_RS04920 4953e32ac6b4ab9b52c868093a18a585 155 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 26 5.9E-9 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS04920 4953e32ac6b4ab9b52c868093a18a585 155 Pfam PF13633 Prokaryotic N-terminal methylation site 3 28 6.9E-10 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS04920 4953e32ac6b4ab9b52c868093a18a585 155 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS04920 4953e32ac6b4ab9b52c868093a18a585 155 SUPERFAMILY SSF54523 6 70 1.1E-12 T 13-09-2016 THL1_RS04180 f374d8cc9fbf09bd16ee0532f70f440f 238 Pfam PF04172 LrgB-like family 23 235 2.9E-73 T 13-09-2016 IPR007300 CidB/LrgB family THL1_RS04180 f374d8cc9fbf09bd16ee0532f70f440f 238 PANTHER PTHR30249:SF5 1 237 1.5E-93 T 13-09-2016 THL1_RS04180 f374d8cc9fbf09bd16ee0532f70f440f 238 PANTHER PTHR30249 1 237 1.5E-93 T 13-09-2016 THL1_RS05610 3b50df0d10151fe9fbf78e6e098fb633 576 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 205 4.1E-18 T 13-09-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 THL1_RS05610 3b50df0d10151fe9fbf78e6e098fb633 576 SUPERFAMILY SSF56519 52 219 9.42E-45 T 13-09-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 THL1_RS05610 3b50df0d10151fe9fbf78e6e098fb633 576 Gene3D G3DSA:3.90.1310.10 127 227 9.3E-28 T 13-09-2016 THL1_RS05610 3b50df0d10151fe9fbf78e6e098fb633 576 Gene3D G3DSA:3.40.710.10 228 551 1.2E-87 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS05610 3b50df0d10151fe9fbf78e6e098fb633 576 Pfam PF00905 Penicillin binding protein transpeptidase domain 245 544 5.3E-85 T 13-09-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THL1_RS05610 3b50df0d10151fe9fbf78e6e098fb633 576 PANTHER PTHR30627:SF1 1 564 1.6E-215 T 13-09-2016 THL1_RS05610 3b50df0d10151fe9fbf78e6e098fb633 576 PANTHER PTHR30627 1 564 1.6E-215 T 13-09-2016 THL1_RS05610 3b50df0d10151fe9fbf78e6e098fb633 576 SUPERFAMILY SSF56601 172 560 1.62E-90 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS09230 a62124a4dd4bdbcecabddc2525d1f5c3 304 Gene3D G3DSA:3.40.190.10 92 176 2.0E-21 T 13-09-2016 THL1_RS09230 a62124a4dd4bdbcecabddc2525d1f5c3 304 Gene3D G3DSA:3.40.190.10 177 261 1.9E-16 T 13-09-2016 THL1_RS09230 a62124a4dd4bdbcecabddc2525d1f5c3 304 Gene3D G3DSA:1.10.10.10 3 88 1.3E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09230 a62124a4dd4bdbcecabddc2525d1f5c3 304 PANTHER PTHR30537 1 300 3.6E-96 T 13-09-2016 THL1_RS09230 a62124a4dd4bdbcecabddc2525d1f5c3 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.1E-19 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS09230 a62124a4dd4bdbcecabddc2525d1f5c3 304 SUPERFAMILY SSF53850 89 300 2.35E-44 T 13-09-2016 THL1_RS09230 a62124a4dd4bdbcecabddc2525d1f5c3 304 PANTHER PTHR30537:SF5 1 300 3.6E-96 T 13-09-2016 THL1_RS09230 a62124a4dd4bdbcecabddc2525d1f5c3 304 SUPERFAMILY SSF46785 3 110 2.72E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09230 a62124a4dd4bdbcecabddc2525d1f5c3 304 Pfam PF03466 LysR substrate binding domain 88 296 9.2E-41 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 SUPERFAMILY SSF54665 52 174 2.44E-11 T 13-09-2016 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 PANTHER PTHR11908 637 681 3.4E-189 T 13-09-2016 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 PANTHER PTHR11908:SF71 117 197 3.4E-189 T 13-09-2016 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 758 880 6.1E-16 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 263 600 4.0E-55 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 Gene3D G3DSA:3.30.365.10 263 371 1.6E-13 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 Gene3D G3DSA:3.30.365.10 790 806 1.8E-18 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 Gene3D G3DSA:3.30.365.10 553 716 1.8E-18 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 PANTHER PTHR11908 239 609 3.4E-189 T 13-09-2016 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 PANTHER PTHR11908:SF71 756 941 3.4E-189 T 13-09-2016 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 Gene3D G3DSA:3.30.365.10 807 941 4.6E-58 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 Gene3D G3DSA:3.30.365.10 451 552 4.6E-58 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 PANTHER PTHR11908:SF71 239 609 3.4E-189 T 13-09-2016 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 PANTHER PTHR11908 117 197 3.4E-189 T 13-09-2016 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 PANTHER PTHR11908 756 941 3.4E-189 T 13-09-2016 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 SUPERFAMILY SSF56003 796 941 2.36E-120 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 SUPERFAMILY SSF56003 637 741 2.36E-120 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 SUPERFAMILY SSF56003 261 609 2.36E-120 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 PANTHER PTHR11908:SF71 637 681 3.4E-189 T 13-09-2016 THL1_RS04630 a3167ca781d3f8193f551bc2c52bc37c 942 Gene3D G3DSA:3.30.365.10 374 450 3.6E-6 T 13-09-2016 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 THL1_RS24840 e2430ca146a06c5332fd7844cadeaf04 396 Pfam PF00482 Type II secretion system (T2SS), protein F 63 186 8.8E-28 T 13-09-2016 IPR018076 Type II secretion system F domain THL1_RS24840 e2430ca146a06c5332fd7844cadeaf04 396 Pfam PF00482 Type II secretion system (T2SS), protein F 266 387 5.2E-26 T 13-09-2016 IPR018076 Type II secretion system F domain THL1_RS24840 e2430ca146a06c5332fd7844cadeaf04 396 PRINTS PR00812 Bacterial general secretion pathway protein F signature 158 186 7.1E-17 T 13-09-2016 IPR003004 GspF/PilC family THL1_RS24840 e2430ca146a06c5332fd7844cadeaf04 396 PRINTS PR00812 Bacterial general secretion pathway protein F signature 376 395 7.1E-17 T 13-09-2016 IPR003004 GspF/PilC family THL1_RS24840 e2430ca146a06c5332fd7844cadeaf04 396 PRINTS PR00812 Bacterial general secretion pathway protein F signature 360 374 7.1E-17 T 13-09-2016 IPR003004 GspF/PilC family THL1_RS24840 e2430ca146a06c5332fd7844cadeaf04 396 PRINTS PR00812 Bacterial general secretion pathway protein F signature 59 71 7.1E-17 T 13-09-2016 IPR003004 GspF/PilC family THL1_RS24840 e2430ca146a06c5332fd7844cadeaf04 396 PANTHER PTHR30012:SF0 1 396 2.2E-94 T 13-09-2016 THL1_RS24840 e2430ca146a06c5332fd7844cadeaf04 396 PANTHER PTHR30012 1 396 2.2E-94 T 13-09-2016 THL1_RS06200 067904036aeb5fc90fc1842d9ca4b95f 487 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 309 337 - T 13-09-2016 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 THL1_RS06200 067904036aeb5fc90fc1842d9ca4b95f 487 Pfam PF01464 Transglycosylase SLT domain 292 399 3.2E-21 T 13-09-2016 IPR008258 Transglycosylase SLT domain 1 THL1_RS06200 067904036aeb5fc90fc1842d9ca4b95f 487 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 265 3.7E-30 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS06200 067904036aeb5fc90fc1842d9ca4b95f 487 Gene3D G3DSA:3.40.190.10 224 257 2.0E-17 T 13-09-2016 THL1_RS06200 067904036aeb5fc90fc1842d9ca4b95f 487 Gene3D G3DSA:3.40.190.10 38 118 2.0E-17 T 13-09-2016 THL1_RS06200 067904036aeb5fc90fc1842d9ca4b95f 487 SUPERFAMILY SSF53850 42 265 1.78E-37 T 13-09-2016 THL1_RS06200 067904036aeb5fc90fc1842d9ca4b95f 487 PANTHER PTHR21666:SF215 271 485 1.0E-115 T 13-09-2016 IPR023703 Membrane-bound lytic murein transglycosylase F GO:0016837 THL1_RS06200 067904036aeb5fc90fc1842d9ca4b95f 487 Gene3D G3DSA:3.40.190.10 119 204 8.6E-9 T 13-09-2016 THL1_RS06200 067904036aeb5fc90fc1842d9ca4b95f 487 SMART SM00062 41 266 9.8E-31 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS06200 067904036aeb5fc90fc1842d9ca4b95f 487 SUPERFAMILY SSF53955 432 450 6.33E-34 T 13-09-2016 IPR023346 Lysozyme-like domain THL1_RS06200 067904036aeb5fc90fc1842d9ca4b95f 487 SUPERFAMILY SSF53955 243 397 6.33E-34 T 13-09-2016 IPR023346 Lysozyme-like domain THL1_RS06200 067904036aeb5fc90fc1842d9ca4b95f 487 Hamap MF_02016 Membrane-bound lytic murein transglycosylase F [mltF]. 11 475 45.415 T 13-09-2016 IPR023703 Membrane-bound lytic murein transglycosylase F GO:0016837 THL1_RS06200 067904036aeb5fc90fc1842d9ca4b95f 487 PANTHER PTHR21666 271 485 1.0E-115 T 13-09-2016 THL1_RS06200 067904036aeb5fc90fc1842d9ca4b95f 487 Gene3D G3DSA:1.10.530.10 429 450 5.0E-38 T 13-09-2016 THL1_RS06200 067904036aeb5fc90fc1842d9ca4b95f 487 Gene3D G3DSA:1.10.530.10 258 394 5.0E-38 T 13-09-2016 THL1_RS14480 efc8013a665e90fe24b8187e641be538 301 Gene3D G3DSA:1.10.10.10 7 90 2.7E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14480 efc8013a665e90fe24b8187e641be538 301 Pfam PF03466 LysR substrate binding domain 96 291 1.6E-41 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS14480 efc8013a665e90fe24b8187e641be538 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 1.1E-14 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14480 efc8013a665e90fe24b8187e641be538 301 PANTHER PTHR30419:SF3 1 291 1.2E-56 T 13-09-2016 THL1_RS14480 efc8013a665e90fe24b8187e641be538 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.4E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14480 efc8013a665e90fe24b8187e641be538 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.4E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14480 efc8013a665e90fe24b8187e641be538 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.4E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14480 efc8013a665e90fe24b8187e641be538 301 PANTHER PTHR30419 1 291 1.2E-56 T 13-09-2016 THL1_RS14480 efc8013a665e90fe24b8187e641be538 301 SUPERFAMILY SSF46785 6 118 4.68E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14480 efc8013a665e90fe24b8187e641be538 301 Gene3D G3DSA:3.40.190.10 188 266 3.6E-14 T 13-09-2016 THL1_RS14480 efc8013a665e90fe24b8187e641be538 301 SUPERFAMILY SSF53850 97 291 5.29E-40 T 13-09-2016 THL1_RS14480 efc8013a665e90fe24b8187e641be538 301 Gene3D G3DSA:3.40.190.10 96 187 1.1E-23 T 13-09-2016 THL1_RS19740 27e729c23c2968d7eb10efa2fd107339 319 PANTHER PTHR30465 4 316 7.9E-95 T 13-09-2016 THL1_RS19740 27e729c23c2968d7eb10efa2fd107339 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 314 2.2E-33 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS19740 27e729c23c2968d7eb10efa2fd107339 319 SUPERFAMILY SSF161098 96 300 1.7E-21 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS19740 27e729c23c2968d7eb10efa2fd107339 319 PANTHER PTHR30465:SF24 4 316 7.9E-95 T 13-09-2016 THL1_RS19740 27e729c23c2968d7eb10efa2fd107339 319 Gene3D G3DSA:1.10.3720.10 94 306 8.4E-22 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS18230 1f19f7e07ca126ebc8619d7ddf48aefc 166 PANTHER PTHR10815 1 156 4.4E-63 T 13-09-2016 THL1_RS18230 1f19f7e07ca126ebc8619d7ddf48aefc 166 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 73 152 3.3E-38 T 13-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 THL1_RS18230 1f19f7e07ca126ebc8619d7ddf48aefc 166 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 123 129 - T 13-09-2016 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 THL1_RS18230 1f19f7e07ca126ebc8619d7ddf48aefc 166 SUPERFAMILY SSF46767 72 155 5.1E-34 T 13-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 THL1_RS18230 1f19f7e07ca126ebc8619d7ddf48aefc 166 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 1 155 39.908 T 13-09-2016 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 THL1_RS18230 1f19f7e07ca126ebc8619d7ddf48aefc 166 PANTHER PTHR10815:SF5 1 156 4.4E-63 T 13-09-2016 THL1_RS18230 1f19f7e07ca126ebc8619d7ddf48aefc 166 SUPERFAMILY SSF53155 1 77 2.75E-18 T 13-09-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 THL1_RS18230 1f19f7e07ca126ebc8619d7ddf48aefc 166 Gene3D G3DSA:1.10.10.10 72 156 9.0E-38 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS18230 1f19f7e07ca126ebc8619d7ddf48aefc 166 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 74 154 1.8E-35 T 13-09-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 THL1_RS18230 1f19f7e07ca126ebc8619d7ddf48aefc 166 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 1 64 7.7E-5 T 13-09-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 THL1_RS14710 a9c4f8c43c2880e2cb603b7904f7bf4a 430 SUPERFAMILY SSF103473 5 417 5.75E-59 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS14710 a9c4f8c43c2880e2cb603b7904f7bf4a 430 Gene3D G3DSA:1.20.1250.20 233 418 9.8E-15 T 13-09-2016 THL1_RS14710 a9c4f8c43c2880e2cb603b7904f7bf4a 430 Gene3D G3DSA:1.20.1250.20 9 216 1.9E-22 T 13-09-2016 THL1_RS14710 a9c4f8c43c2880e2cb603b7904f7bf4a 430 PANTHER PTHR23508:SF1 4 412 2.4E-140 T 13-09-2016 THL1_RS14710 a9c4f8c43c2880e2cb603b7904f7bf4a 430 Pfam PF00083 Sugar (and other) transporter 13 217 3.6E-21 T 13-09-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 THL1_RS14710 a9c4f8c43c2880e2cb603b7904f7bf4a 430 PANTHER PTHR23508 4 412 2.4E-140 T 13-09-2016 THL1_RS19980 421c56dcb28e6caef568662be1cd9ebf 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.3E-24 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19980 421c56dcb28e6caef568662be1cd9ebf 304 PANTHER PTHR30346 1 303 5.5E-117 T 13-09-2016 THL1_RS19980 421c56dcb28e6caef568662be1cd9ebf 304 PANTHER PTHR30346:SF7 1 303 5.5E-117 T 13-09-2016 THL1_RS19980 421c56dcb28e6caef568662be1cd9ebf 304 Gene3D G3DSA:1.10.10.10 1 84 2.6E-32 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19980 421c56dcb28e6caef568662be1cd9ebf 304 Gene3D G3DSA:3.40.190.10 88 172 1.4E-24 T 13-09-2016 THL1_RS19980 421c56dcb28e6caef568662be1cd9ebf 304 Gene3D G3DSA:3.40.190.10 173 268 6.0E-35 T 13-09-2016 THL1_RS19980 421c56dcb28e6caef568662be1cd9ebf 304 Pfam PF03466 LysR substrate binding domain 88 295 6.2E-46 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS19980 421c56dcb28e6caef568662be1cd9ebf 304 SUPERFAMILY SSF53850 91 298 2.57E-39 T 13-09-2016 THL1_RS19980 421c56dcb28e6caef568662be1cd9ebf 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.0E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19980 421c56dcb28e6caef568662be1cd9ebf 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.0E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19980 421c56dcb28e6caef568662be1cd9ebf 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.0E-9 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19980 421c56dcb28e6caef568662be1cd9ebf 304 SUPERFAMILY SSF46785 1 86 2.28E-26 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00790 a6445a920efd94526b4b64428e6b2d60 284 SUPERFAMILY SSF52096 3 237 7.09E-39 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS00790 a6445a920efd94526b4b64428e6b2d60 284 PANTHER PTHR22855:SF21 1 236 4.2E-76 T 13-09-2016 THL1_RS00790 a6445a920efd94526b4b64428e6b2d60 284 TIGRFAM TIGR03133 malonate_beta: biotin-independent malonate decarboxylase, beta subunit 11 261 7.2E-115 T 13-09-2016 IPR017556 Biotin-independent malonate decarboxylase, beta subunit GO:0016831|GO:0044262 MetaCyc: PWY-6060 THL1_RS00790 a6445a920efd94526b4b64428e6b2d60 284 PANTHER PTHR22855 1 236 4.2E-76 T 13-09-2016 THL1_RS00790 a6445a920efd94526b4b64428e6b2d60 284 Pfam PF01039 Carboxyl transferase domain 18 243 2.4E-16 T 13-09-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS00790 a6445a920efd94526b4b64428e6b2d60 284 Gene3D G3DSA:3.90.226.10 15 248 3.7E-34 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS19875 89a4af1821dead4a2b934789cabda5ab 447 Pfam PF00120 Glutamine synthetase, catalytic domain 111 441 4.1E-103 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS19875 89a4af1821dead4a2b934789cabda5ab 447 PANTHER PTHR20852:SF63 4 447 6.6E-213 T 13-09-2016 THL1_RS19875 89a4af1821dead4a2b934789cabda5ab 447 PANTHER PTHR20852 4 447 6.6E-213 T 13-09-2016 THL1_RS19875 89a4af1821dead4a2b934789cabda5ab 447 SUPERFAMILY SSF55931 110 442 1.47E-101 T 13-09-2016 THL1_RS19875 89a4af1821dead4a2b934789cabda5ab 447 SMART SM01230 109 365 1.1E-96 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS19875 89a4af1821dead4a2b934789cabda5ab 447 Gene3D G3DSA:3.10.20.70 15 108 7.1E-4 T 13-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS19875 89a4af1821dead4a2b934789cabda5ab 447 SUPERFAMILY SSF54368 12 107 3.27E-9 T 13-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS19875 89a4af1821dead4a2b934789cabda5ab 447 Gene3D G3DSA:3.30.590.10 112 431 3.7E-90 T 13-09-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 THL1_RS06745 d962c2501436c99b1fc789d69b268480 268 Gene3D G3DSA:3.40.720.10 2 229 6.6E-37 T 13-09-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THL1_RS06745 d962c2501436c99b1fc789d69b268480 268 SUPERFAMILY SSF53649 1 255 5.23E-49 T 13-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THL1_RS06745 d962c2501436c99b1fc789d69b268480 268 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 5 77 1.8E-4 T 13-09-2016 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 THL1_RS06745 d962c2501436c99b1fc789d69b268480 268 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 140 210 7.2E-10 T 13-09-2016 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 THL1_RS12435 f2fa9daa89c987c5c094f95d071ef17b 337 PIRSF PIRSF015753 4 322 5.6E-134 T 13-09-2016 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 THL1_RS12435 f2fa9daa89c987c5c094f95d071ef17b 337 Pfam PF13409 Glutathione S-transferase, N-terminal domain 61 156 5.0E-23 T 13-09-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THL1_RS12435 f2fa9daa89c987c5c094f95d071ef17b 337 PANTHER PTHR32419:SF6 1 331 9.5E-176 T 13-09-2016 THL1_RS12435 f2fa9daa89c987c5c094f95d071ef17b 337 SUPERFAMILY SSF47616 174 321 1.95E-36 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS12435 f2fa9daa89c987c5c094f95d071ef17b 337 Gene3D G3DSA:1.20.1050.10 176 287 4.0E-25 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS12435 f2fa9daa89c987c5c094f95d071ef17b 337 PANTHER PTHR32419 1 331 9.5E-176 T 13-09-2016 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 THL1_RS12435 f2fa9daa89c987c5c094f95d071ef17b 337 SUPERFAMILY SSF52833 40 160 9.96E-16 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS12435 f2fa9daa89c987c5c094f95d071ef17b 337 Gene3D G3DSA:3.40.30.10 39 175 2.3E-18 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS12435 f2fa9daa89c987c5c094f95d071ef17b 337 Pfam PF13410 Glutathione S-transferase, C-terminal domain 202 273 9.9E-12 T 13-09-2016 THL1_RS15880 0ca9ffde847cf2fdec2b8d02c626c435 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 382 4.1E-41 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS15880 0ca9ffde847cf2fdec2b8d02c626c435 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS15880 0ca9ffde847cf2fdec2b8d02c626c435 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS15880 0ca9ffde847cf2fdec2b8d02c626c435 387 PANTHER PTHR10909:SF326 6 387 2.0E-284 T 13-09-2016 THL1_RS15880 0ca9ffde847cf2fdec2b8d02c626c435 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 123 7.8E-37 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS15880 0ca9ffde847cf2fdec2b8d02c626c435 387 SUPERFAMILY SSF56645 5 247 1.96E-87 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS15880 0ca9ffde847cf2fdec2b8d02c626c435 387 Gene3D G3DSA:2.40.110.10 126 223 2.7E-41 T 13-09-2016 THL1_RS15880 0ca9ffde847cf2fdec2b8d02c626c435 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 222 3.1E-27 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS15880 0ca9ffde847cf2fdec2b8d02c626c435 387 SUPERFAMILY SSF47203 233 385 9.02E-45 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS15880 0ca9ffde847cf2fdec2b8d02c626c435 387 Gene3D G3DSA:1.10.540.10 4 124 5.3E-43 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS15880 0ca9ffde847cf2fdec2b8d02c626c435 387 PANTHER PTHR10909 6 387 2.0E-284 T 13-09-2016 THL1_RS15880 0ca9ffde847cf2fdec2b8d02c626c435 387 Gene3D G3DSA:1.20.140.10 224 385 3.6E-63 T 13-09-2016 THL1_RS27485 d927848bcdf268f5336a24778e886e0c 110 ProSitePatterns PS01344 Frataxin family signature. 50 64 - T 13-09-2016 IPR020895 Frataxin conserved site THL1_RS27485 d927848bcdf268f5336a24778e886e0c 110 Gene3D G3DSA:3.30.920.10 2 107 5.4E-29 T 13-09-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 THL1_RS27485 d927848bcdf268f5336a24778e886e0c 110 Pfam PF01491 Frataxin-like domain 3 104 6.9E-25 T 13-09-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 THL1_RS27485 d927848bcdf268f5336a24778e886e0c 110 PANTHER PTHR16821 2 110 1.0E-30 T 13-09-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 THL1_RS27485 d927848bcdf268f5336a24778e886e0c 110 Hamap MF_00142 Protein CyaY [cyaY]. 3 107 25.676 T 13-09-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 THL1_RS27485 d927848bcdf268f5336a24778e886e0c 110 SUPERFAMILY SSF55387 3 107 1.22E-31 T 13-09-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 THL1_RS27485 d927848bcdf268f5336a24778e886e0c 110 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 5 107 2.0E-35 T 13-09-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 THL1_RS27485 d927848bcdf268f5336a24778e886e0c 110 SMART SM01219 3 108 2.1E-48 T 13-09-2016 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 THL1_RS09205 5f8e3c8c74f594facb728a261c2a11a9 324 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 313 1.1E-135 T 13-09-2016 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 THL1_RS09205 5f8e3c8c74f594facb728a261c2a11a9 324 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 313 2.0E-130 T 13-09-2016 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 THL1_RS09205 5f8e3c8c74f594facb728a261c2a11a9 324 SUPERFAMILY SSF53686 5 312 2.62E-98 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS09205 5f8e3c8c74f594facb728a261c2a11a9 324 Gene3D G3DSA:3.40.50.1100 43 143 2.6E-40 T 13-09-2016 THL1_RS09205 5f8e3c8c74f594facb728a261c2a11a9 324 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 302 2.1E-66 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS09205 5f8e3c8c74f594facb728a261c2a11a9 324 Gene3D G3DSA:3.40.50.1100 151 317 8.4E-71 T 13-09-2016 THL1_RS09205 5f8e3c8c74f594facb728a261c2a11a9 324 Gene3D G3DSA:3.40.50.1100 3 42 8.4E-71 T 13-09-2016 THL1_RS09205 5f8e3c8c74f594facb728a261c2a11a9 324 PANTHER PTHR10314:SF110 3 321 1.1E-155 T 13-09-2016 THL1_RS09205 5f8e3c8c74f594facb728a261c2a11a9 324 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 13-09-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 THL1_RS09205 5f8e3c8c74f594facb728a261c2a11a9 324 PANTHER PTHR10314 3 321 1.1E-155 T 13-09-2016 THL1_RS04305 499b1340d0716f1584e008f649696c57 506 SUPERFAMILY SSF56317 221 484 7.33E-47 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS04305 499b1340d0716f1584e008f649696c57 506 PANTHER PTHR38686 1 505 1.6E-105 T 13-09-2016 THL1_RS04305 499b1340d0716f1584e008f649696c57 506 Gene3D G3DSA:3.60.110.10 219 472 4.6E-28 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS04305 499b1340d0716f1584e008f649696c57 506 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 61 452 4.0E-97 T 13-09-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UniPathway: UPA00666 THL1_RS04305 499b1340d0716f1584e008f649696c57 506 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 8 489 23.471 T 13-09-2016 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 UniPathway: UPA00666 THL1_RS04305 499b1340d0716f1584e008f649696c57 506 Pfam PF00795 Carbon-nitrogen hydrolase 226 468 1.1E-31 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS13430 2f38c2d799ecfe4d576f81bb3a3bf11d 99 SUPERFAMILY SSF102829 9 91 8.37E-15 T 13-09-2016 IPR007838 Cell division protein ZapA-like THL1_RS13430 2f38c2d799ecfe4d576f81bb3a3bf11d 99 Pfam PF05164 Cell division protein ZapA 9 90 1.5E-13 T 13-09-2016 IPR007838 Cell division protein ZapA-like THL1_RS05275 ea46ed99701584c0de1184231cf38326 128 PANTHER PTHR34183 32 128 6.8E-51 T 13-09-2016 THL1_RS05275 ea46ed99701584c0de1184231cf38326 128 Gene3D G3DSA:2.40.40.10 36 125 4.8E-7 T 13-09-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain THL1_RS05275 ea46ed99701584c0de1184231cf38326 128 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 37 127 1.8E-44 T 13-09-2016 IPR012997 Rare lipoprotein A THL1_RS05275 ea46ed99701584c0de1184231cf38326 128 Pfam PF03330 Lytic transglycolase 35 124 2.6E-27 T 13-09-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain THL1_RS05275 ea46ed99701584c0de1184231cf38326 128 SUPERFAMILY SSF50685 41 124 6.98E-14 T 13-09-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain THL1_RS08675 997cc176b2b44d6a506ed245dc71cb8d 325 PANTHER PTHR11695:SF590 17 324 8.4E-112 T 13-09-2016 THL1_RS08675 997cc176b2b44d6a506ed245dc71cb8d 325 Gene3D G3DSA:3.90.180.10 13 94 1.6E-16 T 13-09-2016 IPR011032 GroES-like THL1_RS08675 997cc176b2b44d6a506ed245dc71cb8d 325 SMART SM00829 15 323 6.1E-12 T 13-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THL1_RS08675 997cc176b2b44d6a506ed245dc71cb8d 325 Gene3D G3DSA:3.40.50.720 123 292 2.2E-55 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS08675 997cc176b2b44d6a506ed245dc71cb8d 325 Pfam PF00107 Zinc-binding dehydrogenase 152 279 3.9E-17 T 13-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THL1_RS08675 997cc176b2b44d6a506ed245dc71cb8d 325 SUPERFAMILY SSF50129 13 145 2.59E-30 T 13-09-2016 IPR011032 GroES-like THL1_RS08675 997cc176b2b44d6a506ed245dc71cb8d 325 PANTHER PTHR11695 17 324 8.4E-112 T 13-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 THL1_RS08675 997cc176b2b44d6a506ed245dc71cb8d 325 SUPERFAMILY SSF51735 115 291 1.78E-55 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS08675 997cc176b2b44d6a506ed245dc71cb8d 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 91 1.9E-8 T 13-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THL1_RS10410 b858e10fcede5b8b9470f0ae08bdc91f 422 Pfam PF03573 outer membrane porin, OprD family 28 419 2.0E-160 T 13-09-2016 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 THL1_RS10410 b858e10fcede5b8b9470f0ae08bdc91f 422 Gene3D G3DSA:2.40.160.10 32 422 5.7E-157 T 13-09-2016 IPR023614 Porin domain THL1_RS10410 b858e10fcede5b8b9470f0ae08bdc91f 422 PANTHER PTHR34596 1 422 3.2E-177 T 13-09-2016 THL1_RS26135 b7052fed7079cc0a66e454a86fab26d1 305 Gene3D G3DSA:3.90.550.10 2 192 2.4E-40 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS26135 b7052fed7079cc0a66e454a86fab26d1 305 PANTHER PTHR22916 1 223 3.7E-37 T 13-09-2016 THL1_RS26135 b7052fed7079cc0a66e454a86fab26d1 305 Pfam PF00535 Glycosyl transferase family 2 8 171 6.0E-31 T 13-09-2016 IPR001173 Glycosyltransferase 2-like THL1_RS26135 b7052fed7079cc0a66e454a86fab26d1 305 SUPERFAMILY SSF53448 5 219 9.38E-45 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS13090 f17cf014c8963a8ddc46272e8d0c9eb2 368 PANTHER PTHR32089:SF28 105 363 7.1E-31 T 13-09-2016 THL1_RS13090 f17cf014c8963a8ddc46272e8d0c9eb2 368 SUPERFAMILY SSF58104 119 362 1.15E-42 T 13-09-2016 THL1_RS13090 f17cf014c8963a8ddc46272e8d0c9eb2 368 Gene3D G3DSA:1.10.287.950 127 342 3.3E-39 T 13-09-2016 THL1_RS13090 f17cf014c8963a8ddc46272e8d0c9eb2 368 PANTHER PTHR32089 105 363 7.1E-31 T 13-09-2016 THL1_RS13090 f17cf014c8963a8ddc46272e8d0c9eb2 368 SMART SM00283 113 367 6.6E-21 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS13090 f17cf014c8963a8ddc46272e8d0c9eb2 368 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 179 352 3.5E-29 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS28415 ca342aedbdd38c52310318177ec608fb 141 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 133 8.0E-45 T 13-09-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 THL1_RS28415 ca342aedbdd38c52310318177ec608fb 141 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 89 132 5.1E-7 T 13-09-2016 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain THL1_RS28415 ca342aedbdd38c52310318177ec608fb 141 SUPERFAMILY SSF46604 88 137 3.66E-10 T 13-09-2016 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain THL1_RS28415 ca342aedbdd38c52310318177ec608fb 141 PANTHER PTHR13822 4 139 8.3E-41 T 13-09-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 THL1_RS28415 ca342aedbdd38c52310318177ec608fb 141 SUPERFAMILY SSF51344 4 86 9.68E-24 T 13-09-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 THL1_RS28415 ca342aedbdd38c52310318177ec608fb 141 PANTHER PTHR13822:SF7 4 139 8.3E-41 T 13-09-2016 THL1_RS28415 ca342aedbdd38c52310318177ec608fb 141 Gene3D G3DSA:1.20.5.440 92 134 1.9E-13 T 13-09-2016 THL1_RS28415 ca342aedbdd38c52310318177ec608fb 141 Gene3D G3DSA:2.60.15.10 4 91 6.5E-29 T 13-09-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 THL1_RS28415 ca342aedbdd38c52310318177ec608fb 141 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 10 86 7.0E-37 T 13-09-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 THL1_RS28415 ca342aedbdd38c52310318177ec608fb 141 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 6 84 2.2E-30 T 13-09-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 THL1_RS28415 ca342aedbdd38c52310318177ec608fb 141 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 131 19.554 T 13-09-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 THL1_RS05465 8d16e0de0e615cf878bc03e0fadda897 383 SUPERFAMILY SSF50494 52 272 6.26E-64 T 13-09-2016 IPR009003 Peptidase S1, PA clan THL1_RS05465 8d16e0de0e615cf878bc03e0fadda897 383 Pfam PF13365 Trypsin-like peptidase domain 107 241 1.5E-31 T 13-09-2016 THL1_RS05465 8d16e0de0e615cf878bc03e0fadda897 383 SMART SM00228 280 362 5.9E-14 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS05465 8d16e0de0e615cf878bc03e0fadda897 383 Gene3D G3DSA:2.30.42.10 282 377 8.4E-27 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS05465 8d16e0de0e615cf878bc03e0fadda897 383 SUPERFAMILY SSF50156 238 363 2.08E-24 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS05465 8d16e0de0e615cf878bc03e0fadda897 383 PRINTS PR00834 HtrA/DegQ protease family signature 212 229 2.4E-55 T 13-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THL1_RS05465 8d16e0de0e615cf878bc03e0fadda897 383 PRINTS PR00834 HtrA/DegQ protease family signature 234 251 2.4E-55 T 13-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THL1_RS05465 8d16e0de0e615cf878bc03e0fadda897 383 PRINTS PR00834 HtrA/DegQ protease family signature 177 201 2.4E-55 T 13-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THL1_RS05465 8d16e0de0e615cf878bc03e0fadda897 383 PRINTS PR00834 HtrA/DegQ protease family signature 137 157 2.4E-55 T 13-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THL1_RS05465 8d16e0de0e615cf878bc03e0fadda897 383 PRINTS PR00834 HtrA/DegQ protease family signature 116 128 2.4E-55 T 13-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THL1_RS05465 8d16e0de0e615cf878bc03e0fadda897 383 PRINTS PR00834 HtrA/DegQ protease family signature 320 332 2.4E-55 T 13-09-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THL1_RS05465 8d16e0de0e615cf878bc03e0fadda897 383 Gene3D G3DSA:2.40.10.10 53 168 2.3E-35 T 13-09-2016 THL1_RS05465 8d16e0de0e615cf878bc03e0fadda897 383 PANTHER PTHR22939:SF93 1 375 1.3E-171 T 13-09-2016 THL1_RS05465 8d16e0de0e615cf878bc03e0fadda897 383 Pfam PF13180 PDZ domain 280 369 5.6E-16 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS05465 8d16e0de0e615cf878bc03e0fadda897 383 Gene3D G3DSA:2.40.10.10 169 281 2.3E-44 T 13-09-2016 THL1_RS05465 8d16e0de0e615cf878bc03e0fadda897 383 PANTHER PTHR22939 1 375 1.3E-171 T 13-09-2016 THL1_RS14415 48cdaab25696ee468ce45a1ca7bc10be 404 PANTHER PTHR30199 1 394 2.9E-142 T 13-09-2016 THL1_RS14415 48cdaab25696ee468ce45a1ca7bc10be 404 PANTHER PTHR30199:SF0 1 394 2.9E-142 T 13-09-2016 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 THL1_RS14415 48cdaab25696ee468ce45a1ca7bc10be 404 TIGRFAM TIGR00843 benE: benzoate transporter 11 384 5.9E-134 T 13-09-2016 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 THL1_RS14415 48cdaab25696ee468ce45a1ca7bc10be 404 Pfam PF03594 Benzoate membrane transport protein 7 382 1.6E-154 T 13-09-2016 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 THL1_RS05985 0aff152cf5e240b7c0e5b1b7cc5f786f 370 PIRSF PIRSF004640 1 363 4.7E-151 T 13-09-2016 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 THL1_RS05985 0aff152cf5e240b7c0e5b1b7cc5f786f 370 PANTHER PTHR30454 1 367 3.7E-215 T 13-09-2016 THL1_RS05985 0aff152cf5e240b7c0e5b1b7cc5f786f 370 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 7 357 35.39 T 13-09-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 THL1_RS05985 0aff152cf5e240b7c0e5b1b7cc5f786f 370 SUPERFAMILY SSF51412 24 132 1.19E-9 T 13-09-2016 THL1_RS05985 0aff152cf5e240b7c0e5b1b7cc5f786f 370 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 9 352 2.1E-131 T 13-09-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 THL1_RS05985 0aff152cf5e240b7c0e5b1b7cc5f786f 370 Gene3D G3DSA:3.20.20.70 31 132 1.0E-9 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS05985 0aff152cf5e240b7c0e5b1b7cc5f786f 370 Pfam PF04551 GcpE protein 13 353 3.4E-137 T 13-09-2016 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3|UniPathway: UPA00056 THL1_RS05985 0aff152cf5e240b7c0e5b1b7cc5f786f 370 SUPERFAMILY SSF56014 265 353 3.14E-13 T 13-09-2016 THL1_RS13925 78b0c1d1bc799dae3c5fffa1d5d3d0dd 187 Pfam PF06821 Serine hydrolase 9 183 2.6E-40 T 13-09-2016 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 KEGG: 00231+3.-.-.-|KEGG: 00563+3.-.-.-|KEGG: 00983+3.-.-.- THL1_RS13925 78b0c1d1bc799dae3c5fffa1d5d3d0dd 187 SUPERFAMILY SSF53474 7 182 2.53E-27 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS13925 78b0c1d1bc799dae3c5fffa1d5d3d0dd 187 Gene3D G3DSA:3.40.50.1820 5 185 8.7E-37 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS28060 8348f0a3d24043963bbf42bf434412d9 398 PANTHER PTHR30572 20 398 2.9E-73 T 13-09-2016 THL1_RS28060 8348f0a3d24043963bbf42bf434412d9 398 Pfam PF12704 MacB-like periplasmic core domain 21 241 4.4E-32 T 13-09-2016 IPR025857 MacB-like periplasmic core domain THL1_RS28060 8348f0a3d24043963bbf42bf434412d9 398 Pfam PF02687 FtsX-like permease family 278 391 3.3E-19 T 13-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 THL1_RS28400 111044098d91f9385a89ef2c715cf4ad 616 Gene3D G3DSA:3.40.50.10490 450 616 1.7E-66 T 13-09-2016 THL1_RS28400 111044098d91f9385a89ef2c715cf4ad 616 Pfam PF01380 SIS domain 291 423 2.2E-29 T 13-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 THL1_RS28400 111044098d91f9385a89ef2c715cf4ad 616 Pfam PF01380 SIS domain 469 598 6.5E-26 T 13-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 THL1_RS28400 111044098d91f9385a89ef2c715cf4ad 616 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 616 40.888 T 13-09-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 THL1_RS28400 111044098d91f9385a89ef2c715cf4ad 616 PANTHER PTHR10937 1 616 0.0 T 13-09-2016 THL1_RS28400 111044098d91f9385a89ef2c715cf4ad 616 Gene3D G3DSA:3.40.50.10490 245 449 4.3E-65 T 13-09-2016 THL1_RS28400 111044098d91f9385a89ef2c715cf4ad 616 Pfam PF13522 Glutamine amidotransferase domain 67 182 7.2E-21 T 13-09-2016 THL1_RS28400 111044098d91f9385a89ef2c715cf4ad 616 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 616 1.2E-256 T 13-09-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 THL1_RS28400 111044098d91f9385a89ef2c715cf4ad 616 Gene3D G3DSA:3.60.20.10 2 236 3.4E-79 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS28400 111044098d91f9385a89ef2c715cf4ad 616 PANTHER PTHR10937:SF0 1 616 0.0 T 13-09-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 THL1_RS28400 111044098d91f9385a89ef2c715cf4ad 616 SUPERFAMILY SSF56235 2 235 3.26E-75 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS28400 111044098d91f9385a89ef2c715cf4ad 616 SUPERFAMILY SSF53697 246 616 1.39E-115 T 13-09-2016 THL1_RS23870 85b44b020c0309609370f4e88017099b 185 SUPERFAMILY SSF53271 15 183 8.39E-47 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS23870 85b44b020c0309609370f4e88017099b 185 Gene3D G3DSA:3.40.50.2020 8 183 1.8E-57 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS23870 85b44b020c0309609370f4e88017099b 185 PANTHER PTHR22573 7 180 5.0E-58 T 13-09-2016 THL1_RS23870 85b44b020c0309609370f4e88017099b 185 Pfam PF00156 Phosphoribosyl transferase domain 22 156 2.0E-23 T 13-09-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 THL1_RS23870 85b44b020c0309609370f4e88017099b 185 PANTHER PTHR22573:SF56 7 180 5.0E-58 T 13-09-2016 THL1_RS19340 c04023d7e81d04cefe78afdeac440025 111 Gene3D G3DSA:2.40.50.140 2 110 4.5E-34 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS19340 c04023d7e81d04cefe78afdeac440025 111 Pfam PF01588 Putative tRNA binding domain 14 108 7.1E-16 T 13-09-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 THL1_RS19340 c04023d7e81d04cefe78afdeac440025 111 SUPERFAMILY SSF50249 3 110 6.37E-30 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS19340 c04023d7e81d04cefe78afdeac440025 111 PANTHER PTHR11586 4 110 3.5E-31 T 13-09-2016 THL1_RS19340 c04023d7e81d04cefe78afdeac440025 111 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 6 110 1.2E-46 T 13-09-2016 IPR008231 Probable chaperone CsaA THL1_RS14945 7067bb95cec28b2067b4939402d6ff43 99 Pfam PF10734 Protein of unknown function (DUF2523) 6 82 4.2E-21 T 13-09-2016 IPR019670 Protein of unkown function DUF2523 THL1_RS15005 7067bb95cec28b2067b4939402d6ff43 99 Pfam PF10734 Protein of unknown function (DUF2523) 6 82 4.2E-21 T 13-09-2016 IPR019670 Protein of unkown function DUF2523 THL1_RS13445 3288bb641d79121f64ed7e0084b4c8b6 309 PANTHER PTHR30574 1 306 2.1E-12 T 13-09-2016 THL1_RS13445 3288bb641d79121f64ed7e0084b4c8b6 309 Pfam PF04143 Sulphur transport 19 296 6.2E-22 T 13-09-2016 IPR007272 Sulphur transport domain THL1_RS14685 52b56a44bcf3f868330aab4eb35be46f 180 Pfam PF16036 Chalcone isomerase-like 44 174 8.6E-13 T 13-09-2016 IPR016087 Chalcone isomerase GO:0016872 THL1_RS18580 96c1de3a8892e8337330398307fc61c3 238 Pfam PF01863 Protein of unknown function DUF45 28 231 5.7E-58 T 13-09-2016 IPR002725 Protein of unknown function DUF45 THL1_RS18580 96c1de3a8892e8337330398307fc61c3 238 PANTHER PTHR30399 4 230 2.5E-41 T 13-09-2016 THL1_RS20835 9e7007fbafca19ef06d7f5eb75eeb7fb 402 PANTHER PTHR18919 250 402 9.8E-216 T 13-09-2016 THL1_RS20835 9e7007fbafca19ef06d7f5eb75eeb7fb 402 PANTHER PTHR18919:SF12 250 402 9.8E-216 T 13-09-2016 THL1_RS20835 9e7007fbafca19ef06d7f5eb75eeb7fb 402 ProSitePatterns PS00099 Thiolases active site. 383 396 - T 13-09-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 THL1_RS20835 9e7007fbafca19ef06d7f5eb75eeb7fb 402 PANTHER PTHR18919 1 229 9.8E-216 T 13-09-2016 THL1_RS20835 9e7007fbafca19ef06d7f5eb75eeb7fb 402 SUPERFAMILY SSF53901 3 271 2.35E-59 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20835 9e7007fbafca19ef06d7f5eb75eeb7fb 402 Gene3D G3DSA:3.40.47.10 5 127 3.7E-55 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20835 9e7007fbafca19ef06d7f5eb75eeb7fb 402 Gene3D G3DSA:3.40.47.10 186 285 3.7E-55 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20835 9e7007fbafca19ef06d7f5eb75eeb7fb 402 PANTHER PTHR18919:SF12 1 229 9.8E-216 T 13-09-2016 THL1_RS20835 9e7007fbafca19ef06d7f5eb75eeb7fb 402 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 400 2.6E-120 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS20835 9e7007fbafca19ef06d7f5eb75eeb7fb 402 SUPERFAMILY SSF53901 280 401 7.15E-42 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20835 9e7007fbafca19ef06d7f5eb75eeb7fb 402 PIRSF PIRSF000429 1 402 2.1E-106 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS20835 9e7007fbafca19ef06d7f5eb75eeb7fb 402 Pfam PF02803 Thiolase, C-terminal domain 280 401 3.0E-43 T 13-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THL1_RS20835 9e7007fbafca19ef06d7f5eb75eeb7fb 402 Gene3D G3DSA:3.40.47.10 147 185 9.6E-56 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20835 9e7007fbafca19ef06d7f5eb75eeb7fb 402 Gene3D G3DSA:3.40.47.10 286 401 9.6E-56 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20835 9e7007fbafca19ef06d7f5eb75eeb7fb 402 Pfam PF00108 Thiolase, N-terminal domain 5 231 1.1E-39 T 13-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THL1_RS20835 9e7007fbafca19ef06d7f5eb75eeb7fb 402 ProSitePatterns PS00737 Thiolases signature 2. 348 364 - T 13-09-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 THL1_RS19325 4ef919a0c33c0689511958e0e95314b1 343 Pfam PF13439 Glycosyltransferase Family 4 14 164 1.1E-13 T 13-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain THL1_RS19325 4ef919a0c33c0689511958e0e95314b1 343 PANTHER PTHR12526:SF363 1 322 5.7E-68 T 13-09-2016 THL1_RS19325 4ef919a0c33c0689511958e0e95314b1 343 Gene3D G3DSA:3.40.50.2000 158 297 1.3E-19 T 13-09-2016 THL1_RS19325 4ef919a0c33c0689511958e0e95314b1 343 SUPERFAMILY SSF53756 1 324 5.1E-65 T 13-09-2016 THL1_RS19325 4ef919a0c33c0689511958e0e95314b1 343 Pfam PF13692 Glycosyl transferases group 1 178 290 1.8E-18 T 13-09-2016 THL1_RS19325 4ef919a0c33c0689511958e0e95314b1 343 PANTHER PTHR12526 1 322 5.7E-68 T 13-09-2016 THL1_RS11265 c3664861b94871ee33f796240ed5b761 489 PANTHER PTHR23023 7 485 3.9E-232 T 13-09-2016 THL1_RS11265 c3664861b94871ee33f796240ed5b761 489 SUPERFAMILY SSF51905 12 232 9.26E-56 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS11265 c3664861b94871ee33f796240ed5b761 489 SUPERFAMILY SSF51905 299 398 9.26E-56 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS11265 c3664861b94871ee33f796240ed5b761 489 Gene3D G3DSA:3.50.50.60 12 221 3.7E-61 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS11265 c3664861b94871ee33f796240ed5b761 489 Gene3D G3DSA:3.50.50.60 325 480 4.8E-17 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS11265 c3664861b94871ee33f796240ed5b761 489 PANTHER PTHR23023:SF132 7 485 3.9E-232 T 13-09-2016 THL1_RS11265 c3664861b94871ee33f796240ed5b761 489 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 14 209 3.5E-18 T 13-09-2016 THL1_RS14650 5b33a041bc3a59074576cb1f4f3198d3 339 Pfam PF10282 Lactonase, 7-bladed beta-propeller 97 221 8.1E-8 T 13-09-2016 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31|UniPathway: UPA00115 THL1_RS14650 5b33a041bc3a59074576cb1f4f3198d3 339 Gene3D G3DSA:2.130.10.10 21 334 1.3E-63 T 13-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THL1_RS14650 5b33a041bc3a59074576cb1f4f3198d3 339 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 162 202 8.6E-18 T 13-09-2016 IPR011964 YVTN beta-propeller repeat THL1_RS14650 5b33a041bc3a59074576cb1f4f3198d3 339 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 294 333 2.2E-8 T 13-09-2016 IPR011964 YVTN beta-propeller repeat THL1_RS14650 5b33a041bc3a59074576cb1f4f3198d3 339 SUPERFAMILY SSF50974 14 333 2.38E-58 T 13-09-2016 IPR011045 Nitrous oxide reductase, N-terminal THL1_RS14650 5b33a041bc3a59074576cb1f4f3198d3 339 PANTHER PTHR13833 110 331 6.0E-32 T 13-09-2016 THL1_RS24935 52b8af36fd056efc3ba63d9c1dbbb9de 95 Gene3D G3DSA:2.60.120.10 4 91 5.9E-14 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS24935 52b8af36fd056efc3ba63d9c1dbbb9de 95 Pfam PF07883 Cupin domain 23 91 1.9E-8 T 13-09-2016 IPR013096 Cupin 2, conserved barrel THL1_RS24935 52b8af36fd056efc3ba63d9c1dbbb9de 95 SUPERFAMILY SSF51182 3 91 2.72E-15 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS05575 d709c7ed2c589863f979f951d7bdbf1a 122 Hamap MF_00048 UPF0102 protein YraN [yraN]. 4 115 23.228 T 13-09-2016 IPR003509 Uncharacterised protein family UPF0102 THL1_RS05575 d709c7ed2c589863f979f951d7bdbf1a 122 SUPERFAMILY SSF52980 5 108 9.65E-18 T 13-09-2016 IPR011335 Restriction endonuclease type II-like THL1_RS05575 d709c7ed2c589863f979f951d7bdbf1a 122 PANTHER PTHR34039:SF1 1 121 4.7E-41 T 13-09-2016 THL1_RS05575 d709c7ed2c589863f979f951d7bdbf1a 122 Pfam PF02021 Uncharacterised protein family UPF0102 11 102 8.4E-25 T 13-09-2016 IPR003509 Uncharacterised protein family UPF0102 THL1_RS05575 d709c7ed2c589863f979f951d7bdbf1a 122 PANTHER PTHR34039 1 121 4.7E-41 T 13-09-2016 THL1_RS05575 d709c7ed2c589863f979f951d7bdbf1a 122 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 5 122 2.9E-35 T 13-09-2016 IPR003509 Uncharacterised protein family UPF0102 THL1_RS05575 d709c7ed2c589863f979f951d7bdbf1a 122 Gene3D G3DSA:3.40.1350.10 11 121 4.1E-36 T 13-09-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 THL1_RS07160 b1aecbce9e3f78b093bbf6a4571b0d7f 302 SMART SM00859 6 121 9.3E-6 T 13-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THL1_RS07160 b1aecbce9e3f78b093bbf6a4571b0d7f 302 PIRSF PIRSF015689 1 298 6.0E-131 T 13-09-2016 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 THL1_RS07160 b1aecbce9e3f78b093bbf6a4571b0d7f 302 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 131 268 1.2E-64 T 13-09-2016 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 THL1_RS07160 b1aecbce9e3f78b093bbf6a4571b0d7f 302 SUPERFAMILY SSF51735 1 155 3.02E-29 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS07160 b1aecbce9e3f78b093bbf6a4571b0d7f 302 SUPERFAMILY SSF55347 131 269 3.33E-60 T 13-09-2016 THL1_RS07160 b1aecbce9e3f78b093bbf6a4571b0d7f 302 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 119 3.4E-11 T 13-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THL1_RS07160 b1aecbce9e3f78b093bbf6a4571b0d7f 302 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 4 292 4.2E-141 T 13-09-2016 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 THL1_RS07160 b1aecbce9e3f78b093bbf6a4571b0d7f 302 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 302 143.931 T 13-09-2016 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 THL1_RS07160 b1aecbce9e3f78b093bbf6a4571b0d7f 302 Gene3D G3DSA:3.30.360.10 144 268 4.3E-66 T 13-09-2016 THL1_RS07160 b1aecbce9e3f78b093bbf6a4571b0d7f 302 PANTHER PTHR41706 1 300 3.0E-122 T 13-09-2016 THL1_RS07160 b1aecbce9e3f78b093bbf6a4571b0d7f 302 Gene3D G3DSA:3.40.50.720 1 143 6.0E-72 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS27905 6793ad9c1db82baafbb83c61104483fc 204 PANTHER PTHR30086:SF13 2 201 1.1E-65 T 13-09-2016 THL1_RS27905 6793ad9c1db82baafbb83c61104483fc 204 Pfam PF01810 LysE type translocator 15 202 1.6E-18 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS27905 6793ad9c1db82baafbb83c61104483fc 204 PANTHER PTHR30086 2 201 1.1E-65 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS03565 43d943fdff8762a5af4da0a3d457304e 63 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 3.5E-21 T 13-09-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03565 43d943fdff8762a5af4da0a3d457304e 63 Gene3D G3DSA:1.10.287.310 1 60 6.7E-27 T 13-09-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03565 43d943fdff8762a5af4da0a3d457304e 63 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 17.77 T 13-09-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03565 43d943fdff8762a5af4da0a3d457304e 63 SUPERFAMILY SSF46561 1 61 2.88E-21 T 13-09-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03565 43d943fdff8762a5af4da0a3d457304e 63 Pfam PF00831 Ribosomal L29 protein 4 59 5.3E-23 T 13-09-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03565 43d943fdff8762a5af4da0a3d457304e 63 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 13-09-2016 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03565 43d943fdff8762a5af4da0a3d457304e 63 PANTHER PTHR10916 1 63 2.7E-27 T 13-09-2016 THL1_RS26105 780003e48b9da1bd9ce95e5b1b801047 137 Gene3D G3DSA:2.60.120.10 48 112 4.2E-4 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS26105 780003e48b9da1bd9ce95e5b1b801047 137 Pfam PF05523 WxcM-like, C-terminal 4 131 3.0E-49 T 13-09-2016 IPR008894 WxcM-like, C-terminal MetaCyc: PWY-6953|MetaCyc: PWY-7688 THL1_RS26105 780003e48b9da1bd9ce95e5b1b801047 137 SUPERFAMILY SSF51182 4 132 6.17E-43 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS21795 ed03f41eb43953fb3cb377a89e95b921 559 SUPERFAMILY SSF51905 11 129 1.12E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21795 ed03f41eb43953fb3cb377a89e95b921 559 SUPERFAMILY SSF51905 265 342 1.12E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21795 ed03f41eb43953fb3cb377a89e95b921 559 SUPERFAMILY SSF51905 487 547 1.12E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21795 ed03f41eb43953fb3cb377a89e95b921 559 SUPERFAMILY SSF51905 164 222 1.12E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21795 ed03f41eb43953fb3cb377a89e95b921 559 SUPERFAMILY SSF56425 334 470 6.28E-22 T 13-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain THL1_RS21795 ed03f41eb43953fb3cb377a89e95b921 559 PANTHER PTHR11632 266 544 8.1E-40 T 13-09-2016 THL1_RS21795 ed03f41eb43953fb3cb377a89e95b921 559 PANTHER PTHR11632 22 136 8.1E-40 T 13-09-2016 THL1_RS21795 ed03f41eb43953fb3cb377a89e95b921 559 PANTHER PTHR11632 165 225 8.1E-40 T 13-09-2016 THL1_RS21795 ed03f41eb43953fb3cb377a89e95b921 559 Gene3D G3DSA:3.50.50.60 260 325 1.0E-60 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21795 ed03f41eb43953fb3cb377a89e95b921 559 Gene3D G3DSA:3.50.50.60 10 219 1.0E-60 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21795 ed03f41eb43953fb3cb377a89e95b921 559 Gene3D G3DSA:3.50.50.60 484 545 1.0E-60 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS21795 ed03f41eb43953fb3cb377a89e95b921 559 Gene3D G3DSA:3.90.700.10 335 470 8.4E-23 T 13-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain THL1_RS21795 ed03f41eb43953fb3cb377a89e95b921 559 Pfam PF00890 FAD binding domain 27 521 1.7E-40 T 13-09-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain THL1_RS17435 ff4e05570377215eb6f87c88b1a7d01f 249 SUPERFAMILY SSF52402 1 242 1.33E-83 T 13-09-2016 THL1_RS17435 ff4e05570377215eb6f87c88b1a7d01f 249 Gene3D G3DSA:3.40.50.620 1 247 4.4E-102 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS17435 ff4e05570377215eb6f87c88b1a7d01f 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 13-09-2016 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 THL1_RS17435 ff4e05570377215eb6f87c88b1a7d01f 249 SMART SM00893 23 211 8.1E-66 T 13-09-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 THL1_RS17435 ff4e05570377215eb6f87c88b1a7d01f 249 Pfam PF01012 Electron transfer flavoprotein domain 29 206 6.1E-45 T 13-09-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 THL1_RS17435 ff4e05570377215eb6f87c88b1a7d01f 249 PANTHER PTHR21294:SF8 1 249 5.4E-148 T 13-09-2016 THL1_RS17435 ff4e05570377215eb6f87c88b1a7d01f 249 PIRSF PIRSF000090 1 249 7.5E-81 T 13-09-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 THL1_RS17435 ff4e05570377215eb6f87c88b1a7d01f 249 PANTHER PTHR21294 1 249 5.4E-148 T 13-09-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 THL1_RS19995 32460a959f3035942c1282bf985fa911 358 PIRSF PIRSF009283 1 356 1.0E-116 T 13-09-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 THL1_RS19995 32460a959f3035942c1282bf985fa911 358 Gene3D G3DSA:3.10.180.10 5 147 7.0E-48 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS19995 32460a959f3035942c1282bf985fa911 358 Gene3D G3DSA:3.10.180.10 157 355 1.1E-66 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS19995 32460a959f3035942c1282bf985fa911 358 PANTHER PTHR11959:SF1 6 358 7.9E-113 T 13-09-2016 THL1_RS19995 32460a959f3035942c1282bf985fa911 358 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 5 143 2.4E-69 T 13-09-2016 THL1_RS19995 32460a959f3035942c1282bf985fa911 358 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 160 280 5.0E-21 T 13-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain THL1_RS19995 32460a959f3035942c1282bf985fa911 358 SUPERFAMILY SSF54593 5 342 1.12E-83 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS19995 32460a959f3035942c1282bf985fa911 358 PANTHER PTHR11959 6 358 7.9E-113 T 13-09-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 THL1_RS19995 32460a959f3035942c1282bf985fa911 358 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 12 355 2.2E-125 T 13-09-2016 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 THL1_RS06875 7118a7b060eb931743ef29a85a680aa0 464 SMART SM00155 192 219 3.3E-4 T 13-09-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 THL1_RS06875 7118a7b060eb931743ef29a85a680aa0 464 SMART SM00155 377 404 0.038 T 13-09-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 THL1_RS06875 7118a7b060eb931743ef29a85a680aa0 464 Gene3D G3DSA:3.30.870.10 299 440 8.0E-36 T 13-09-2016 THL1_RS06875 7118a7b060eb931743ef29a85a680aa0 464 PANTHER PTHR21248:SF5 81 458 4.0E-99 T 13-09-2016 THL1_RS06875 7118a7b060eb931743ef29a85a680aa0 464 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 86 458 3.1E-93 T 13-09-2016 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 THL1_RS06875 7118a7b060eb931743ef29a85a680aa0 464 Gene3D G3DSA:3.30.870.10 85 296 1.1E-49 T 13-09-2016 THL1_RS06875 7118a7b060eb931743ef29a85a680aa0 464 SUPERFAMILY SSF56024 253 448 3.36E-44 T 13-09-2016 THL1_RS06875 7118a7b060eb931743ef29a85a680aa0 464 SUPERFAMILY SSF56024 86 296 5.61E-47 T 13-09-2016 THL1_RS06875 7118a7b060eb931743ef29a85a680aa0 464 Pfam PF13091 PLD-like domain 108 216 3.6E-11 T 13-09-2016 IPR025202 Phospholipase D-like domain THL1_RS06875 7118a7b060eb931743ef29a85a680aa0 464 Pfam PF13091 PLD-like domain 304 428 4.9E-26 T 13-09-2016 IPR025202 Phospholipase D-like domain THL1_RS06875 7118a7b060eb931743ef29a85a680aa0 464 PANTHER PTHR21248 81 458 4.0E-99 T 13-09-2016 THL1_RS17800 17146cf327c49d13434d6632d1d83dca 236 PANTHER PTHR23029 4 225 1.3E-26 T 13-09-2016 THL1_RS17800 17146cf327c49d13434d6632d1d83dca 236 SUPERFAMILY SSF53254 4 232 2.62E-38 T 13-09-2016 IPR029033 Histidine phosphatase superfamily THL1_RS17800 17146cf327c49d13434d6632d1d83dca 236 SMART SM00855 3 179 1.0E-11 T 13-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 THL1_RS17800 17146cf327c49d13434d6632d1d83dca 236 Gene3D G3DSA:3.40.50.1240 4 225 2.6E-33 T 13-09-2016 IPR029033 Histidine phosphatase superfamily THL1_RS17800 17146cf327c49d13434d6632d1d83dca 236 PANTHER PTHR23029:SF1 4 225 1.3E-26 T 13-09-2016 THL1_RS17800 17146cf327c49d13434d6632d1d83dca 236 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 115 219 1.9E-10 T 13-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 THL1_RS17800 17146cf327c49d13434d6632d1d83dca 236 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 90 7.6E-12 T 13-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 THL1_RS24330 899096cb3a6e47366b5290e45fa26c68 291 PANTHER PTHR36151 1 291 5.3E-104 T 13-09-2016 THL1_RS24330 899096cb3a6e47366b5290e45fa26c68 291 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 42 270 6.5E-57 T 13-09-2016 IPR018713 Domain of unknown function DUF2236 THL1_RS24330 899096cb3a6e47366b5290e45fa26c68 291 PANTHER PTHR36151:SF3 1 291 5.3E-104 T 13-09-2016 THL1_RS06550 a37a5bcb1fa18831b665ba26c65dc998 421 Gene3D G3DSA:1.20.1250.20 7 196 5.8E-19 T 13-09-2016 THL1_RS06550 a37a5bcb1fa18831b665ba26c65dc998 421 SUPERFAMILY SSF103473 6 407 4.05E-39 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS06550 a37a5bcb1fa18831b665ba26c65dc998 421 PANTHER PTHR11662 33 402 2.9E-46 T 13-09-2016 THL1_RS06550 a37a5bcb1fa18831b665ba26c65dc998 421 Gene3D G3DSA:1.20.1250.20 211 404 1.8E-8 T 13-09-2016 THL1_RS06550 a37a5bcb1fa18831b665ba26c65dc998 421 PANTHER PTHR11662:SF283 33 402 2.9E-46 T 13-09-2016 THL1_RS06550 a37a5bcb1fa18831b665ba26c65dc998 421 Pfam PF07690 Major Facilitator Superfamily 35 362 5.2E-19 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS13960 f552913fa860060fe8da0133f398e26c 307 PANTHER PTHR10587:SF72 8 295 3.7E-138 T 13-09-2016 THL1_RS13960 f552913fa860060fe8da0133f398e26c 307 Pfam PF01522 Polysaccharide deacetylase 73 175 3.4E-14 T 13-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 THL1_RS13960 f552913fa860060fe8da0133f398e26c 307 Gene3D G3DSA:3.20.20.370 3 297 6.6E-98 T 13-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 THL1_RS13960 f552913fa860060fe8da0133f398e26c 307 PANTHER PTHR10587 8 295 3.7E-138 T 13-09-2016 THL1_RS13960 f552913fa860060fe8da0133f398e26c 307 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 3 297 6.1E-130 T 13-09-2016 IPR017625 Putative urate catabolism protein THL1_RS13960 f552913fa860060fe8da0133f398e26c 307 SUPERFAMILY SSF88713 3 297 4.73E-89 T 13-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THL1_RS27470 4678bbcf90ed09000afedf3a83e25be3 80 TIGRFAM TIGR02647 DNA: TIGR02647 family protein 1 75 2.1E-39 T 13-09-2016 IPR013468 Conserved hypothetical protein CHP02647 THL1_RS27470 4678bbcf90ed09000afedf3a83e25be3 80 Pfam PF06146 Phosphate-starvation-inducible E 7 71 7.6E-14 T 13-09-2016 IPR020948 Phosphate-starvation-induced PsiE-like THL1_RS01885 9877dcf1c3ef09120542d9aef9b9c841 188 PANTHER PTHR33420 1 188 1.1E-32 T 13-09-2016 THL1_RS01885 9877dcf1c3ef09120542d9aef9b9c841 188 Gene3D G3DSA:2.60.40.1090 28 188 1.2E-28 T 13-09-2016 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 THL1_RS01885 9877dcf1c3ef09120542d9aef9b9c841 188 SUPERFAMILY SSF49401 29 188 4.77E-25 T 13-09-2016 IPR008966 Adhesion domain THL1_RS01885 9877dcf1c3ef09120542d9aef9b9c841 188 Pfam PF00419 Fimbrial protein 30 187 1.5E-14 T 13-09-2016 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 THL1_RS05270 02c820db316fbff2ee6d625163697f46 125 PANTHER PTHR33570 2 125 1.1E-54 T 13-09-2016 THL1_RS05270 02c820db316fbff2ee6d625163697f46 125 Pfam PF02627 Carboxymuconolactone decarboxylase family 35 117 3.3E-27 T 13-09-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS05270 02c820db316fbff2ee6d625163697f46 125 SUPERFAMILY SSF69118 4 120 1.7E-40 T 13-09-2016 IPR029032 AhpD-like THL1_RS05270 02c820db316fbff2ee6d625163697f46 125 Gene3D G3DSA:1.20.1290.10 3 124 3.6E-39 T 13-09-2016 IPR029032 AhpD-like THL1_RS05270 02c820db316fbff2ee6d625163697f46 125 PANTHER PTHR33570:SF2 2 125 1.1E-54 T 13-09-2016 THL1_RS02365 c4a7e0390ef362bf9fdb7b1d78b361d2 190 PANTHER PTHR30543:SF6 1 182 2.1E-49 T 13-09-2016 THL1_RS02365 c4a7e0390ef362bf9fdb7b1d78b361d2 190 SUPERFAMILY SSF52218 5 175 7.92E-44 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS02365 c4a7e0390ef362bf9fdb7b1d78b361d2 190 Pfam PF03358 NADPH-dependent FMN reductase 5 148 1.5E-31 T 13-09-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 THL1_RS02365 c4a7e0390ef362bf9fdb7b1d78b361d2 190 PANTHER PTHR30543 1 182 2.1E-49 T 13-09-2016 THL1_RS02365 c4a7e0390ef362bf9fdb7b1d78b361d2 190 Gene3D G3DSA:3.40.50.360 1 180 3.5E-45 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS27965 cf5e2fa61db8c2bcafb524959d531a46 55 PRINTS PR00163 Rubredoxin signature 3 19 2.5E-9 T 13-09-2016 IPR024935 Rubredoxin domain GO:0005506 THL1_RS27965 cf5e2fa61db8c2bcafb524959d531a46 55 PRINTS PR00163 Rubredoxin signature 33 49 2.5E-9 T 13-09-2016 IPR024935 Rubredoxin domain GO:0005506 THL1_RS27965 cf5e2fa61db8c2bcafb524959d531a46 55 Gene3D G3DSA:2.20.28.10 1 54 1.7E-27 T 13-09-2016 IPR004039 Rubredoxin-type fold THL1_RS27965 cf5e2fa61db8c2bcafb524959d531a46 55 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 13-09-2016 IPR018527 Rubredoxin, iron-binding site GO:0046872 THL1_RS27965 cf5e2fa61db8c2bcafb524959d531a46 55 Pfam PF00301 Rubredoxin 3 49 1.9E-23 T 13-09-2016 IPR024935 Rubredoxin domain GO:0005506 THL1_RS27965 cf5e2fa61db8c2bcafb524959d531a46 55 PIRSF PIRSF000071 1 55 8.7E-26 T 13-09-2016 IPR024922 Rubredoxin GO:0005506|GO:0009055 THL1_RS27965 cf5e2fa61db8c2bcafb524959d531a46 55 SUPERFAMILY SSF57802 1 53 2.52E-23 T 13-09-2016 THL1_RS03090 77a919be85574da5d1ef65cc76884403 266 Gene3D G3DSA:3.40.50.300 64 229 4.0E-25 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03090 77a919be85574da5d1ef65cc76884403 266 SMART SM00382 95 232 8.1E-7 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS03090 77a919be85574da5d1ef65cc76884403 266 SUPERFAMILY SSF52540 87 230 7.04E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03090 77a919be85574da5d1ef65cc76884403 266 PANTHER PTHR30050 4 236 2.3E-67 T 13-09-2016 THL1_RS03090 77a919be85574da5d1ef65cc76884403 266 Pfam PF01695 IstB-like ATP binding protein 52 228 1.9E-66 T 13-09-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 THL1_RS03090 77a919be85574da5d1ef65cc76884403 266 PANTHER PTHR30050:SF6 4 236 2.3E-67 T 13-09-2016 THL1_RS03090 77a919be85574da5d1ef65cc76884403 266 PIRSF PIRSF003073 1 250 2.1E-69 T 13-09-2016 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein THL1_RS26705 5002ff5d65578043545909abd646f34c 137 PANTHER PTHR12231:SF138 30 137 2.5E-29 T 13-09-2016 THL1_RS26705 5002ff5d65578043545909abd646f34c 137 PANTHER PTHR12231 30 137 2.5E-29 T 13-09-2016 THL1_RS26705 5002ff5d65578043545909abd646f34c 137 SUPERFAMILY SSF52821 14 137 1.57E-30 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS26705 5002ff5d65578043545909abd646f34c 137 SMART SM00450 38 134 3.5E-18 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS26705 5002ff5d65578043545909abd646f34c 137 Gene3D G3DSA:3.40.250.10 38 136 1.7E-25 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS26705 5002ff5d65578043545909abd646f34c 137 Pfam PF00581 Rhodanese-like domain 40 129 9.2E-11 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS09105 f9c394ed0dfe3d7ffcf87d6413ceb1df 391 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 10 385 6.3E-157 T 13-09-2016 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936|UniPathway: UPA00051 THL1_RS09105 f9c394ed0dfe3d7ffcf87d6413ceb1df 391 SUPERFAMILY SSF53383 40 385 2.69E-104 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS09105 f9c394ed0dfe3d7ffcf87d6413ceb1df 391 PANTHER PTHR11808 9 388 4.1E-196 T 13-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 THL1_RS09105 f9c394ed0dfe3d7ffcf87d6413ceb1df 391 PANTHER PTHR11808:SF45 9 388 4.1E-196 T 13-09-2016 THL1_RS09105 f9c394ed0dfe3d7ffcf87d6413ceb1df 391 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 198 212 - T 13-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 THL1_RS09105 f9c394ed0dfe3d7ffcf87d6413ceb1df 391 PIRSF PIRSF001434 2 387 1.1E-127 T 13-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 THL1_RS09105 f9c394ed0dfe3d7ffcf87d6413ceb1df 391 Gene3D G3DSA:3.90.1150.10 255 386 1.0E-35 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS09105 f9c394ed0dfe3d7ffcf87d6413ceb1df 391 Gene3D G3DSA:3.40.640.10 8 254 1.3E-83 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS09105 f9c394ed0dfe3d7ffcf87d6413ceb1df 391 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 383 5.4E-112 T 13-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 THL1_RS15550 fae03d64751c35d98dac9cf033c3fc41 576 PANTHER PTHR12815:SF12 11 576 5.1E-201 T 13-09-2016 THL1_RS15550 fae03d64751c35d98dac9cf033c3fc41 576 Gene3D G3DSA:2.40.160.50 391 573 2.1E-23 T 13-09-2016 THL1_RS15550 fae03d64751c35d98dac9cf033c3fc41 576 Pfam PF01103 Surface antigen 379 573 3.2E-33 T 13-09-2016 IPR000184 Bacterial surface antigen (D15) GO:0019867 THL1_RS15550 fae03d64751c35d98dac9cf033c3fc41 576 PANTHER PTHR12815 11 576 5.1E-201 T 13-09-2016 THL1_RS17950 ba08716be6f129cb2a8d6448941f19ed 535 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 268 3.2E-5 T 13-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THL1_RS17950 ba08716be6f129cb2a8d6448941f19ed 535 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 503 527 5.1E-4 T 13-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THL1_RS17950 ba08716be6f129cb2a8d6448941f19ed 535 SUPERFAMILY SSF52540 274 523 6.69E-66 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17950 ba08716be6f129cb2a8d6448941f19ed 535 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS17950 ba08716be6f129cb2a8d6448941f19ed 535 Pfam PF00005 ABC transporter 302 452 2.8E-28 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS17950 ba08716be6f129cb2a8d6448941f19ed 535 Pfam PF00005 ABC transporter 26 184 1.3E-27 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS17950 ba08716be6f129cb2a8d6448941f19ed 535 PANTHER PTHR24220:SF574 7 410 5.7E-198 T 13-09-2016 THL1_RS17950 ba08716be6f129cb2a8d6448941f19ed 535 SMART SM00382 34 234 7.8E-15 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS17950 ba08716be6f129cb2a8d6448941f19ed 535 SMART SM00382 310 500 4.2E-17 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS17950 ba08716be6f129cb2a8d6448941f19ed 535 Gene3D G3DSA:3.40.50.300 4 258 7.7E-74 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17950 ba08716be6f129cb2a8d6448941f19ed 535 Gene3D G3DSA:3.40.50.300 273 525 5.1E-75 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17950 ba08716be6f129cb2a8d6448941f19ed 535 ProSitePatterns PS00211 ABC transporters family signature. 424 438 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS17950 ba08716be6f129cb2a8d6448941f19ed 535 PANTHER PTHR24220 7 410 5.7E-198 T 13-09-2016 THL1_RS17950 ba08716be6f129cb2a8d6448941f19ed 535 SUPERFAMILY SSF52540 5 256 8.72E-68 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01640 e373b663c7a3c0bb9c865bd4f9a338a6 349 Gene3D G3DSA:3.30.360.10 170 326 1.4E-57 T 13-09-2016 THL1_RS01640 e373b663c7a3c0bb9c865bd4f9a338a6 349 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 155 173 1.6E-24 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS01640 e373b663c7a3c0bb9c865bd4f9a338a6 349 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 239 256 1.6E-24 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS01640 e373b663c7a3c0bb9c865bd4f9a338a6 349 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 280 295 1.6E-24 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS01640 e373b663c7a3c0bb9c865bd4f9a338a6 349 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 116 129 1.6E-24 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS01640 e373b663c7a3c0bb9c865bd4f9a338a6 349 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 182 198 1.6E-24 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS01640 e373b663c7a3c0bb9c865bd4f9a338a6 349 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 8 161 2.9E-48 T 13-09-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS01640 e373b663c7a3c0bb9c865bd4f9a338a6 349 Gene3D G3DSA:3.40.50.720 6 169 3.3E-56 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS01640 e373b663c7a3c0bb9c865bd4f9a338a6 349 SMART SM00846 7 161 5.5E-68 T 13-09-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS01640 e373b663c7a3c0bb9c865bd4f9a338a6 349 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 167 323 1.7E-50 T 13-09-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS01640 e373b663c7a3c0bb9c865bd4f9a338a6 349 PANTHER PTHR10836 1 349 4.0E-220 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS01640 e373b663c7a3c0bb9c865bd4f9a338a6 349 PANTHER PTHR10836:SF47 1 349 4.0E-220 T 13-09-2016 THL1_RS01640 e373b663c7a3c0bb9c865bd4f9a338a6 349 PIRSF PIRSF000149 5 346 2.6E-130 T 13-09-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 THL1_RS01640 e373b663c7a3c0bb9c865bd4f9a338a6 349 TIGRFAM TIGR01532 E4PD_g-proteo: erythrose-4-phosphate dehydrogenase 8 336 4.2E-177 T 13-09-2016 IPR006422 D-erythrose-4-phosphate dehydrogenase GO:0005737|GO:0042823|GO:0048001|GO:0051287|GO:0055114 KEGG: 00750+1.2.1.72|UniPathway: UPA00244 THL1_RS01640 e373b663c7a3c0bb9c865bd4f9a338a6 349 SUPERFAMILY SSF55347 161 325 2.05E-56 T 13-09-2016 THL1_RS01640 e373b663c7a3c0bb9c865bd4f9a338a6 349 SUPERFAMILY SSF51735 8 176 3.16E-51 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS14890 ac713564460bc42e7d9b2ea41d083b2a 294 Pfam PF05707 Zonular occludens toxin (Zot) 2 193 7.0E-26 T 13-09-2016 IPR008900 Zona occludens toxin THL1_RS14890 ac713564460bc42e7d9b2ea41d083b2a 294 Gene3D G3DSA:3.40.50.300 1 195 1.7E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14840 ac713564460bc42e7d9b2ea41d083b2a 294 Pfam PF05707 Zonular occludens toxin (Zot) 2 193 7.0E-26 T 13-09-2016 IPR008900 Zona occludens toxin THL1_RS14840 ac713564460bc42e7d9b2ea41d083b2a 294 Gene3D G3DSA:3.40.50.300 1 195 1.7E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14305 8d00f4287472a7912d2da5a334a88e3d 394 SUPERFAMILY SSF54373 175 275 7.85E-47 T 13-09-2016 THL1_RS14305 8d00f4287472a7912d2da5a334a88e3d 394 Gene3D G3DSA:3.50.50.60 2 67 5.3E-6 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS14305 8d00f4287472a7912d2da5a334a88e3d 394 PANTHER PTHR13789:SF192 1 394 1.5E-216 T 13-09-2016 THL1_RS14305 8d00f4287472a7912d2da5a334a88e3d 394 Gene3D G3DSA:3.30.9.10 147 299 1.5E-70 T 13-09-2016 THL1_RS14305 8d00f4287472a7912d2da5a334a88e3d 394 TIGRFAM TIGR02360 pbenz_hydroxyl: 4-hydroxybenzoate 3-monooxygenase 1 390 3.5E-216 T 13-09-2016 IPR012733 4-hydroxybenzoate 3-monooxygenase GO:0018659|GO:0043639|GO:0050660|GO:0055114 THL1_RS14305 8d00f4287472a7912d2da5a334a88e3d 394 PANTHER PTHR13789 1 394 1.5E-216 T 13-09-2016 THL1_RS14305 8d00f4287472a7912d2da5a334a88e3d 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 3.7E-31 T 13-09-2016 THL1_RS14305 8d00f4287472a7912d2da5a334a88e3d 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.7E-31 T 13-09-2016 THL1_RS14305 8d00f4287472a7912d2da5a334a88e3d 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 3.7E-31 T 13-09-2016 THL1_RS14305 8d00f4287472a7912d2da5a334a88e3d 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 310 328 3.7E-31 T 13-09-2016 THL1_RS14305 8d00f4287472a7912d2da5a334a88e3d 394 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 3.7E-31 T 13-09-2016 THL1_RS14305 8d00f4287472a7912d2da5a334a88e3d 394 Pfam PF01494 FAD binding domain 2 343 1.4E-93 T 13-09-2016 IPR002938 FAD-binding domain GO:0071949 THL1_RS14305 8d00f4287472a7912d2da5a334a88e3d 394 Gene3D G3DSA:3.50.50.60 93 146 4.2E-5 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS14305 8d00f4287472a7912d2da5a334a88e3d 394 SUPERFAMILY SSF51905 1 172 6.41E-58 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS14305 8d00f4287472a7912d2da5a334a88e3d 394 SUPERFAMILY SSF51905 274 390 6.41E-58 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS26430 6a8af4d749ec4b8ded088aacd57bbf46 530 Gene3D G3DSA:3.90.1200.10 253 297 3.7E-4 T 13-09-2016 THL1_RS26430 6a8af4d749ec4b8ded088aacd57bbf46 530 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 7 445 4.9E-175 T 13-09-2016 IPR010232 Probable protein kinase UbiB GO:0006744 UniPathway: UPA00232 THL1_RS26430 6a8af4d749ec4b8ded088aacd57bbf46 530 PANTHER PTHR10566:SF79 7 443 3.0E-263 T 13-09-2016 THL1_RS26430 6a8af4d749ec4b8ded088aacd57bbf46 530 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 3 530 52.866 T 13-09-2016 IPR010232 Probable protein kinase UbiB GO:0006744 UniPathway: UPA00232 THL1_RS26430 6a8af4d749ec4b8ded088aacd57bbf46 530 PANTHER PTHR10566 7 443 3.0E-263 T 13-09-2016 THL1_RS26430 6a8af4d749ec4b8ded088aacd57bbf46 530 SUPERFAMILY SSF56112 96 159 3.78E-49 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS26430 6a8af4d749ec4b8ded088aacd57bbf46 530 SUPERFAMILY SSF56112 194 437 3.78E-49 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS26430 6a8af4d749ec4b8ded088aacd57bbf46 530 Pfam PF03109 ABC1 family 113 232 4.2E-36 T 13-09-2016 IPR004147 UbiB domain THL1_RS15570 62e9f5523afe0ded0456419f64aaf625 455 SUPERFAMILY SSF53850 42 62 1.09E-61 T 13-09-2016 THL1_RS15570 62e9f5523afe0ded0456419f64aaf625 455 SUPERFAMILY SSF53850 93 364 1.09E-61 T 13-09-2016 THL1_RS15570 62e9f5523afe0ded0456419f64aaf625 455 PANTHER PTHR30570:SF1 1 64 1.0E-67 T 13-09-2016 THL1_RS15570 62e9f5523afe0ded0456419f64aaf625 455 PANTHER PTHR30570:SF1 90 319 1.0E-67 T 13-09-2016 THL1_RS15570 62e9f5523afe0ded0456419f64aaf625 455 SUPERFAMILY SSF103088 330 454 2.88E-19 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS15570 62e9f5523afe0ded0456419f64aaf625 455 Pfam PF12849 PBP superfamily domain 90 306 1.0E-31 T 13-09-2016 IPR024370 PBP domain THL1_RS15570 62e9f5523afe0ded0456419f64aaf625 455 Pfam PF00691 OmpA family 354 448 2.2E-10 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS15570 62e9f5523afe0ded0456419f64aaf625 455 PANTHER PTHR30570 1 64 1.0E-67 T 13-09-2016 THL1_RS15570 62e9f5523afe0ded0456419f64aaf625 455 PANTHER PTHR30570 90 319 1.0E-67 T 13-09-2016 THL1_RS15570 62e9f5523afe0ded0456419f64aaf625 455 Gene3D G3DSA:3.40.190.10 150 282 3.0E-33 T 13-09-2016 THL1_RS15570 62e9f5523afe0ded0456419f64aaf625 455 Gene3D G3DSA:3.30.1330.60 340 454 4.9E-20 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS22155 677d476ca437a66b59b1cd69ee423ce3 355 SUPERFAMILY SSF55073 191 345 2.43E-43 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS22155 677d476ca437a66b59b1cd69ee423ce3 355 Pfam PF00990 Diguanylate cyclase, GGDEF domain 186 343 1.4E-42 T 13-09-2016 IPR000160 GGDEF domain THL1_RS22155 677d476ca437a66b59b1cd69ee423ce3 355 SMART SM00267 175 347 8.5E-52 T 13-09-2016 IPR000160 GGDEF domain THL1_RS22155 677d476ca437a66b59b1cd69ee423ce3 355 PANTHER PTHR10799:SF750 54 101 3.0E-28 T 13-09-2016 THL1_RS22155 677d476ca437a66b59b1cd69ee423ce3 355 PANTHER PTHR10799:SF750 216 344 3.0E-28 T 13-09-2016 THL1_RS22155 677d476ca437a66b59b1cd69ee423ce3 355 PANTHER PTHR10799 54 101 3.0E-28 T 13-09-2016 THL1_RS22155 677d476ca437a66b59b1cd69ee423ce3 355 PANTHER PTHR10799 216 344 3.0E-28 T 13-09-2016 THL1_RS22155 677d476ca437a66b59b1cd69ee423ce3 355 Gene3D G3DSA:3.30.70.270 188 345 6.6E-49 T 13-09-2016 THL1_RS22155 677d476ca437a66b59b1cd69ee423ce3 355 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 185 345 1.1E-42 T 13-09-2016 IPR000160 GGDEF domain THL1_RS22065 d7d5f2d7c35f61e9324f9e339ca06f4c 352 Pfam PF02445 Quinolinate synthetase A protein 34 339 2.8E-105 T 13-09-2016 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 THL1_RS22065 d7d5f2d7c35f61e9324f9e339ca06f4c 352 SUPERFAMILY SSF142754 31 340 2.75E-110 T 13-09-2016 THL1_RS22065 d7d5f2d7c35f61e9324f9e339ca06f4c 352 PANTHER PTHR30573 18 351 1.3E-159 T 13-09-2016 THL1_RS22065 d7d5f2d7c35f61e9324f9e339ca06f4c 352 Hamap MF_00567 Quinolinate synthase A [nadA]. 1 346 70.093 T 13-09-2016 IPR023513 Quinolinate synthase A, type 1 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 THL1_RS22065 d7d5f2d7c35f61e9324f9e339ca06f4c 352 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 30 341 4.3E-111 T 13-09-2016 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342|UniPathway: UPA00253 THL1_RS25575 00774d835c780bb3d4662414c25b3f40 101 Gene3D G3DSA:2.10.150.10 1 101 1.8E-51 T 13-09-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25575 00774d835c780bb3d4662414c25b3f40 101 SUPERFAMILY SSF51278 1 101 1.7E-48 T 13-09-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25575 00774d835c780bb3d4662414c25b3f40 101 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 33.206 T 13-09-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25575 00774d835c780bb3d4662414c25b3f40 101 Pfam PF00699 Urease beta subunit 3 100 8.9E-47 T 13-09-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25575 00774d835c780bb3d4662414c25b3f40 101 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 100 1.4E-46 T 13-09-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25575 00774d835c780bb3d4662414c25b3f40 101 PANTHER PTHR33569:SF1 1 101 3.7E-67 T 13-09-2016 THL1_RS25575 00774d835c780bb3d4662414c25b3f40 101 PANTHER PTHR33569 1 101 3.7E-67 T 13-09-2016 THL1_RS15630 e820dea81b17e464d47703a659677576 374 TIGRFAM TIGR03907 QH_beta: quinohemoprotein amine dehydrogenase, beta subunit 36 374 9.3E-158 T 13-09-2016 IPR023879 Quinohemoprotein amine dehydrogenase, beta subunit THL1_RS15630 e820dea81b17e464d47703a659677576 374 Gene3D G3DSA:2.130.10.10 32 370 2.5E-49 T 13-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THL1_RS15630 e820dea81b17e464d47703a659677576 374 SUPERFAMILY SSF50969 34 368 1.33E-43 T 13-09-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like THL1_RS11150 db8ff05d21a3c5fa279189319d096682 297 Pfam PF03466 LysR substrate binding domain 90 294 3.9E-36 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS11150 db8ff05d21a3c5fa279189319d096682 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 3.2E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS11150 db8ff05d21a3c5fa279189319d096682 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 3.2E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS11150 db8ff05d21a3c5fa279189319d096682 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 3.2E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS11150 db8ff05d21a3c5fa279189319d096682 297 Gene3D G3DSA:3.40.190.10 94 179 1.4E-13 T 13-09-2016 THL1_RS11150 db8ff05d21a3c5fa279189319d096682 297 SUPERFAMILY SSF53850 91 294 1.25E-40 T 13-09-2016 THL1_RS11150 db8ff05d21a3c5fa279189319d096682 297 PANTHER PTHR30537:SF1 1 294 8.9E-169 T 13-09-2016 THL1_RS11150 db8ff05d21a3c5fa279189319d096682 297 PANTHER PTHR30537 1 294 8.9E-169 T 13-09-2016 THL1_RS11150 db8ff05d21a3c5fa279189319d096682 297 Gene3D G3DSA:3.40.190.10 180 263 1.5E-9 T 13-09-2016 THL1_RS11150 db8ff05d21a3c5fa279189319d096682 297 SUPERFAMILY SSF46785 6 90 3.63E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11150 db8ff05d21a3c5fa279189319d096682 297 Gene3D G3DSA:1.10.10.10 5 79 3.3E-26 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11150 db8ff05d21a3c5fa279189319d096682 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 1.4E-23 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS17020 3916db87276a311fe696f21096162574 275 Pfam PF10134 Replication initiator protein A 28 257 3.5E-93 T 13-09-2016 IPR018777 Replication initiator protein A THL1_RS28470 e2f049e97cbc6fef4339aafba3b6f7a2 215 PANTHER PTHR31760 1 213 2.1E-71 T 13-09-2016 THL1_RS28470 e2f049e97cbc6fef4339aafba3b6f7a2 215 PIRSF PIRSF003078 5 214 3.9E-58 T 13-09-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 THL1_RS28470 e2f049e97cbc6fef4339aafba3b6f7a2 215 PANTHER PTHR31760:SF0 1 213 2.1E-71 T 13-09-2016 THL1_RS28470 e2f049e97cbc6fef4339aafba3b6f7a2 215 Pfam PF02527 rRNA small subunit methyltransferase G 28 208 1.9E-62 T 13-09-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 THL1_RS28470 e2f049e97cbc6fef4339aafba3b6f7a2 215 SUPERFAMILY SSF53335 11 213 5.89E-33 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS28470 e2f049e97cbc6fef4339aafba3b6f7a2 215 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 20 210 27.721 T 13-09-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 THL1_RS28470 e2f049e97cbc6fef4339aafba3b6f7a2 215 Gene3D G3DSA:3.40.50.150 11 213 1.6E-62 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS28470 e2f049e97cbc6fef4339aafba3b6f7a2 215 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 32 212 1.3E-57 T 13-09-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 THL1_RS28285 2954ec41c48dfac6442cac16cbf7c5ba 586 Pfam PF00999 Sodium/hydrogen exchanger family 12 376 1.7E-63 T 13-09-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 THL1_RS28285 2954ec41c48dfac6442cac16cbf7c5ba 586 PANTHER PTHR16254 557 575 1.5E-110 T 13-09-2016 THL1_RS28285 2954ec41c48dfac6442cac16cbf7c5ba 586 PANTHER PTHR16254 6 389 1.5E-110 T 13-09-2016 THL1_RS09985 192d35302245bd1845433a4a130a20ea 149 SUPERFAMILY SSF54637 3 145 4.24E-40 T 13-09-2016 IPR029069 HotDog domain THL1_RS09985 192d35302245bd1845433a4a130a20ea 149 PANTHER PTHR31793 7 135 2.1E-72 T 13-09-2016 THL1_RS09985 192d35302245bd1845433a4a130a20ea 149 Pfam PF13279 Thioesterase-like superfamily 15 134 4.6E-11 T 13-09-2016 THL1_RS09985 192d35302245bd1845433a4a130a20ea 149 Gene3D G3DSA:3.10.129.10 4 140 1.5E-34 T 13-09-2016 IPR029069 HotDog domain THL1_RS09985 192d35302245bd1845433a4a130a20ea 149 PANTHER PTHR31793:SF6 7 135 2.1E-72 T 13-09-2016 THL1_RS19770 d8c1c37c38b843c40c9791e4bb7a9753 536 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 420 439 - T 13-09-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 THL1_RS19770 d8c1c37c38b843c40c9791e4bb7a9753 536 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 198 327 1.4E-27 T 13-09-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 THL1_RS19770 d8c1c37c38b843c40c9791e4bb7a9753 536 Gene3D G3DSA:3.40.50.970 2 182 1.4E-59 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS19770 d8c1c37c38b843c40c9791e4bb7a9753 536 PANTHER PTHR18968:SF13 1 530 1.8E-172 T 13-09-2016 THL1_RS19770 d8c1c37c38b843c40c9791e4bb7a9753 536 SUPERFAMILY SSF52518 3 184 5.89E-53 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS19770 d8c1c37c38b843c40c9791e4bb7a9753 536 SUPERFAMILY SSF52467 161 353 3.9E-39 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS19770 d8c1c37c38b843c40c9791e4bb7a9753 536 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 529 2.2E-28 T 13-09-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THL1_RS19770 d8c1c37c38b843c40c9791e4bb7a9753 536 PANTHER PTHR18968 1 530 1.8E-172 T 13-09-2016 THL1_RS19770 d8c1c37c38b843c40c9791e4bb7a9753 536 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 176 2.1E-53 T 13-09-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 THL1_RS19770 d8c1c37c38b843c40c9791e4bb7a9753 536 Gene3D G3DSA:3.40.50.1220 192 376 2.1E-41 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS19770 d8c1c37c38b843c40c9791e4bb7a9753 536 SUPERFAMILY SSF52518 363 534 6.28E-43 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS19770 d8c1c37c38b843c40c9791e4bb7a9753 536 Gene3D G3DSA:3.40.50.970 377 531 2.8E-42 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS23455 c3dcd3ab384d46bfca452afd0c3b1f35 173 Gene3D G3DSA:1.10.1740.10 14 107 7.0E-12 T 13-09-2016 THL1_RS23455 c3dcd3ab384d46bfca452afd0c3b1f35 173 PANTHER PTHR30173:SF9 14 167 1.9E-39 T 13-09-2016 THL1_RS23455 c3dcd3ab384d46bfca452afd0c3b1f35 173 PANTHER PTHR30173 14 167 1.9E-39 T 13-09-2016 THL1_RS23455 c3dcd3ab384d46bfca452afd0c3b1f35 173 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 166 2.4E-20 T 13-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS23455 c3dcd3ab384d46bfca452afd0c3b1f35 173 SUPERFAMILY SSF88659 108 168 2.62E-13 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS23455 c3dcd3ab384d46bfca452afd0c3b1f35 173 Pfam PF08281 Sigma-70, region 4 115 167 3.1E-15 T 13-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS23455 c3dcd3ab384d46bfca452afd0c3b1f35 173 SUPERFAMILY SSF88946 14 104 3.22E-14 T 13-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS23455 c3dcd3ab384d46bfca452afd0c3b1f35 173 Pfam PF04542 Sigma-70 region 2 19 84 2.2E-14 T 13-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS23455 c3dcd3ab384d46bfca452afd0c3b1f35 173 Gene3D G3DSA:1.10.10.10 113 167 2.4E-13 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS15400 aba45cd9be786b5872e7d74c80410f8e 173 SUPERFAMILY SSF57561 56 172 5.62E-55 T 13-09-2016 IPR013504 Methylamine/Aralkylamine dehydrogenase light chain, C-terminal domain GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967|UniPathway: UPA00895 THL1_RS15400 aba45cd9be786b5872e7d74c80410f8e 173 Pfam PF02975 Methylamine dehydrogenase, L chain 62 170 3.1E-52 T 13-09-2016 IPR013504 Methylamine/Aralkylamine dehydrogenase light chain, C-terminal domain GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967|UniPathway: UPA00895 THL1_RS15400 aba45cd9be786b5872e7d74c80410f8e 173 PIRSF PIRSF000192 1 173 4.2E-52 T 13-09-2016 IPR016008 Amine dehydrogenase light chain GO:0009308|GO:0030058|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967|UniPathway: UPA00895 THL1_RS15400 aba45cd9be786b5872e7d74c80410f8e 173 Gene3D G3DSA:2.60.30.10 36 172 1.3E-61 T 13-09-2016 IPR013504 Methylamine/Aralkylamine dehydrogenase light chain, C-terminal domain GO:0009308|GO:0016638|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967|UniPathway: UPA00895 THL1_RS16720 c9363bca4f97e8946eb30ec6dd7dfc38 226 SUPERFAMILY SSF46894 122 222 7.65E-28 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS16720 c9363bca4f97e8946eb30ec6dd7dfc38 226 SMART SM00862 146 221 1.5E-24 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS16720 c9363bca4f97e8946eb30ec6dd7dfc38 226 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 221 8.2E-99 T 13-09-2016 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 THL1_RS16720 c9363bca4f97e8946eb30ec6dd7dfc38 226 SUPERFAMILY SSF52172 1 118 3.56E-38 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS16720 c9363bca4f97e8946eb30ec6dd7dfc38 226 SMART SM00448 1 112 3.3E-39 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS16720 c9363bca4f97e8946eb30ec6dd7dfc38 226 Gene3D G3DSA:3.40.50.2300 1 122 2.0E-38 T 13-09-2016 THL1_RS16720 c9363bca4f97e8946eb30ec6dd7dfc38 226 Gene3D G3DSA:1.10.10.10 123 223 4.5E-31 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS16720 c9363bca4f97e8946eb30ec6dd7dfc38 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 1.7E-24 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS16720 c9363bca4f97e8946eb30ec6dd7dfc38 226 PANTHER PTHR26402:SF575 1 226 2.9E-105 T 13-09-2016 THL1_RS16720 c9363bca4f97e8946eb30ec6dd7dfc38 226 Pfam PF00072 Response regulator receiver domain 4 113 1.9E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS16720 c9363bca4f97e8946eb30ec6dd7dfc38 226 PANTHER PTHR26402 1 226 2.9E-105 T 13-09-2016 THL1_RS13520 b13302f50baab46734e91fef9c723f55 229 PANTHER PTHR26402 1 221 3.7E-84 T 13-09-2016 THL1_RS13520 b13302f50baab46734e91fef9c723f55 229 Gene3D G3DSA:1.10.10.10 125 217 1.3E-28 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13520 b13302f50baab46734e91fef9c723f55 229 SMART SM00448 1 112 2.5E-35 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS13520 b13302f50baab46734e91fef9c723f55 229 SUPERFAMILY SSF52172 1 170 1.08E-36 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS13520 b13302f50baab46734e91fef9c723f55 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 3.0E-22 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS13520 b13302f50baab46734e91fef9c723f55 229 Gene3D G3DSA:3.40.50.2300 1 120 1.5E-33 T 13-09-2016 THL1_RS13520 b13302f50baab46734e91fef9c723f55 229 Pfam PF00072 Response regulator receiver domain 3 112 1.9E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS13520 b13302f50baab46734e91fef9c723f55 229 SMART SM00862 145 216 2.2E-26 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS13520 b13302f50baab46734e91fef9c723f55 229 PANTHER PTHR26402:SF399 1 221 3.7E-84 T 13-09-2016 THL1_RS26090 1c26f029cbfed949d95a9f741c16c67e 599 Gene3D G3DSA:1.20.1560.10 16 337 3.7E-70 T 13-09-2016 THL1_RS26090 1c26f029cbfed949d95a9f741c16c67e 599 Pfam PF00005 ABC transporter 371 519 1.3E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS26090 1c26f029cbfed949d95a9f741c16c67e 599 SUPERFAMILY SSF52540 343 589 1.96E-94 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26090 1c26f029cbfed949d95a9f741c16c67e 599 PANTHER PTHR24221 10 598 7.6E-229 T 13-09-2016 THL1_RS26090 1c26f029cbfed949d95a9f741c16c67e 599 SUPERFAMILY SSF90123 16 337 2.75E-72 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS26090 1c26f029cbfed949d95a9f741c16c67e 599 Pfam PF00664 ABC transporter transmembrane region 29 302 7.0E-49 T 13-09-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 THL1_RS26090 1c26f029cbfed949d95a9f741c16c67e 599 Gene3D G3DSA:3.40.50.300 351 583 1.6E-84 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26090 1c26f029cbfed949d95a9f741c16c67e 599 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS26090 1c26f029cbfed949d95a9f741c16c67e 599 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 13 592 3.0E-254 T 13-09-2016 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 THL1_RS26090 1c26f029cbfed949d95a9f741c16c67e 599 SMART SM00382 378 565 2.3E-18 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS19685 2ff4b3b00b571ed6f38ef21244861131 237 Hamap MF_00415 Flagellar L-ring protein [flgH]. 1 234 29.867 T 13-09-2016 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 THL1_RS19685 2ff4b3b00b571ed6f38ef21244861131 237 PANTHER PTHR34933:SF2 1 237 3.3E-105 T 13-09-2016 THL1_RS19685 2ff4b3b00b571ed6f38ef21244861131 237 PRINTS PR01008 Flagellar L-ring protein signature 197 211 4.6E-19 T 13-09-2016 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 THL1_RS19685 2ff4b3b00b571ed6f38ef21244861131 237 PRINTS PR01008 Flagellar L-ring protein signature 66 78 4.6E-19 T 13-09-2016 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 THL1_RS19685 2ff4b3b00b571ed6f38ef21244861131 237 PRINTS PR01008 Flagellar L-ring protein signature 176 192 4.6E-19 T 13-09-2016 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 THL1_RS19685 2ff4b3b00b571ed6f38ef21244861131 237 PRINTS PR01008 Flagellar L-ring protein signature 213 227 4.6E-19 T 13-09-2016 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 THL1_RS19685 2ff4b3b00b571ed6f38ef21244861131 237 PANTHER PTHR34933 1 237 3.3E-105 T 13-09-2016 THL1_RS19685 2ff4b3b00b571ed6f38ef21244861131 237 Pfam PF02107 Flagellar L-ring protein 44 232 3.5E-59 T 13-09-2016 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 THL1_RS22710 6aab7d9b71d28184e185e0912b1e6026 69 Pfam PF00313 'Cold-shock' DNA-binding domain 7 68 1.8E-27 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS22710 6aab7d9b71d28184e185e0912b1e6026 69 PANTHER PTHR11544 1 66 4.6E-35 T 13-09-2016 THL1_RS22710 6aab7d9b71d28184e185e0912b1e6026 69 SUPERFAMILY SSF50249 4 68 8.78E-24 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS22710 6aab7d9b71d28184e185e0912b1e6026 69 PIRSF PIRSF002599 1 69 2.0E-22 T 13-09-2016 IPR012156 Cold shock, CspA GO:0003676 THL1_RS22710 6aab7d9b71d28184e185e0912b1e6026 69 SMART SM00357 6 69 3.2E-26 T 13-09-2016 IPR011129 Cold shock protein GO:0003676 THL1_RS22710 6aab7d9b71d28184e185e0912b1e6026 69 PRINTS PR00050 Cold shock protein signature 27 36 6.2E-18 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS22710 6aab7d9b71d28184e185e0912b1e6026 69 PRINTS PR00050 Cold shock protein signature 42 60 6.2E-18 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS22710 6aab7d9b71d28184e185e0912b1e6026 69 PRINTS PR00050 Cold shock protein signature 7 22 6.2E-18 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS22710 6aab7d9b71d28184e185e0912b1e6026 69 Gene3D G3DSA:2.40.50.140 6 67 8.9E-29 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS22710 6aab7d9b71d28184e185e0912b1e6026 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 36 - T 13-09-2016 IPR019844 Cold-shock conserved site THL1_RS18885 fc4b5ad70dcd1d71cc95319d14778730 182 SUPERFAMILY SSF53271 6 177 3.67E-49 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS18885 fc4b5ad70dcd1d71cc95319d14778730 182 Gene3D G3DSA:3.40.50.2020 7 176 2.7E-60 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS18885 fc4b5ad70dcd1d71cc95319d14778730 182 Pfam PF00156 Phosphoribosyl transferase domain 31 157 1.1E-14 T 13-09-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 THL1_RS18885 fc4b5ad70dcd1d71cc95319d14778730 182 PANTHER PTHR11776:SF0 8 164 5.6E-68 T 13-09-2016 THL1_RS18885 fc4b5ad70dcd1d71cc95319d14778730 182 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 8 177 35.016 T 13-09-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 THL1_RS18885 fc4b5ad70dcd1d71cc95319d14778730 182 PANTHER PTHR11776 8 164 5.6E-68 T 13-09-2016 THL1_RS18885 fc4b5ad70dcd1d71cc95319d14778730 182 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 8 174 2.3E-57 T 13-09-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 THL1_RS27610 5a555c15bb3130f1dcd7092a497cb3e5 462 PANTHER PTHR11785:SF24 4 447 9.5E-173 T 13-09-2016 THL1_RS27610 5a555c15bb3130f1dcd7092a497cb3e5 462 PIRSF PIRSF006060 1 460 7.4E-70 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS27610 5a555c15bb3130f1dcd7092a497cb3e5 462 ProSitePatterns PS00218 Amino acid permeases signature. 42 72 - T 13-09-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 THL1_RS27610 5a555c15bb3130f1dcd7092a497cb3e5 462 Pfam PF00324 Amino acid permease 17 425 2.0E-94 T 13-09-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 THL1_RS27610 5a555c15bb3130f1dcd7092a497cb3e5 462 PANTHER PTHR11785 4 447 9.5E-173 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS13170 68753410fdb197c5ca763be60bafca0e 123 Gene3D G3DSA:1.10.1660.10 1 55 5.4E-23 T 13-09-2016 THL1_RS13170 68753410fdb197c5ca763be60bafca0e 123 SUPERFAMILY SSF46955 1 116 1.94E-32 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS13170 68753410fdb197c5ca763be60bafca0e 123 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.6E-10 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS13170 68753410fdb197c5ca763be60bafca0e 123 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 5.6E-10 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS13170 68753410fdb197c5ca763be60bafca0e 123 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.6E-10 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS13170 68753410fdb197c5ca763be60bafca0e 123 PANTHER PTHR30204:SF16 1 116 1.4E-36 T 13-09-2016 THL1_RS13170 68753410fdb197c5ca763be60bafca0e 123 Pfam PF13411 MerR HTH family regulatory protein 1 68 7.9E-17 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS13170 68753410fdb197c5ca763be60bafca0e 123 PANTHER PTHR30204 1 116 1.4E-36 T 13-09-2016 THL1_RS13170 68753410fdb197c5ca763be60bafca0e 123 Gene3D G3DSA:1.10.1660.10 56 117 4.3E-20 T 13-09-2016 THL1_RS13170 68753410fdb197c5ca763be60bafca0e 123 SMART SM00422 1 70 1.2E-27 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS14635 7452ffe5365ec2f2f119b0d127ce6501 346 Gene3D G3DSA:1.10.10.60 292 341 6.4E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS14635 7452ffe5365ec2f2f119b0d127ce6501 346 PANTHER PTHR11019:SF90 34 53 1.7E-41 T 13-09-2016 THL1_RS14635 7452ffe5365ec2f2f119b0d127ce6501 346 PANTHER PTHR11019:SF90 79 346 1.7E-41 T 13-09-2016 THL1_RS14635 7452ffe5365ec2f2f119b0d127ce6501 346 SMART SM00342 255 338 1.2E-29 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS14635 7452ffe5365ec2f2f119b0d127ce6501 346 Pfam PF01965 DJ-1/PfpI family 31 199 2.7E-11 T 13-09-2016 IPR002818 DJ-1/PfpI THL1_RS14635 7452ffe5365ec2f2f119b0d127ce6501 346 SUPERFAMILY SSF46689 291 342 2.42E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS14635 7452ffe5365ec2f2f119b0d127ce6501 346 Gene3D G3DSA:3.40.50.880 30 215 5.6E-29 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS14635 7452ffe5365ec2f2f119b0d127ce6501 346 SUPERFAMILY SSF52317 30 218 6.87E-34 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS14635 7452ffe5365ec2f2f119b0d127ce6501 346 Pfam PF12833 Helix-turn-helix domain 261 340 2.4E-22 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS14635 7452ffe5365ec2f2f119b0d127ce6501 346 Gene3D G3DSA:1.10.10.60 239 291 1.7E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS14635 7452ffe5365ec2f2f119b0d127ce6501 346 SUPERFAMILY SSF46689 239 289 6.57E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS14635 7452ffe5365ec2f2f119b0d127ce6501 346 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 292 334 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS14635 7452ffe5365ec2f2f119b0d127ce6501 346 PANTHER PTHR11019 34 53 1.7E-41 T 13-09-2016 THL1_RS14635 7452ffe5365ec2f2f119b0d127ce6501 346 PANTHER PTHR11019 79 346 1.7E-41 T 13-09-2016 THL1_RS12400 8833716555411060bad77495532947bb 316 Gene3D G3DSA:3.50.50.60 119 244 7.0E-34 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12400 8833716555411060bad77495532947bb 316 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 13-09-2016 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 THL1_RS12400 8833716555411060bad77495532947bb 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 1.9E-38 T 13-09-2016 THL1_RS12400 8833716555411060bad77495532947bb 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 1.9E-38 T 13-09-2016 THL1_RS12400 8833716555411060bad77495532947bb 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 1.9E-38 T 13-09-2016 THL1_RS12400 8833716555411060bad77495532947bb 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.9E-38 T 13-09-2016 THL1_RS12400 8833716555411060bad77495532947bb 316 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 1.9E-38 T 13-09-2016 THL1_RS12400 8833716555411060bad77495532947bb 316 Gene3D G3DSA:3.50.50.60 5 118 1.8E-32 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12400 8833716555411060bad77495532947bb 316 PANTHER PTHR22912 1 315 1.3E-165 T 13-09-2016 THL1_RS12400 8833716555411060bad77495532947bb 316 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 313 5.2E-120 T 13-09-2016 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 THL1_RS12400 8833716555411060bad77495532947bb 316 SUPERFAMILY SSF51905 2 313 3.76E-55 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12400 8833716555411060bad77495532947bb 316 PANTHER PTHR22912:SF48 1 315 1.3E-165 T 13-09-2016 THL1_RS12400 8833716555411060bad77495532947bb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 1.1E-75 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS12400 8833716555411060bad77495532947bb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 1.1E-75 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS12400 8833716555411060bad77495532947bb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 1.1E-75 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS12400 8833716555411060bad77495532947bb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 1.1E-75 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS12400 8833716555411060bad77495532947bb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 1.1E-75 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS12400 8833716555411060bad77495532947bb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 1.1E-75 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS12400 8833716555411060bad77495532947bb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 1.1E-75 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS12400 8833716555411060bad77495532947bb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 1.1E-75 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS12400 8833716555411060bad77495532947bb 316 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 1.1E-75 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS12400 8833716555411060bad77495532947bb 316 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 301 5.1E-48 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS10520 26280c9604833007cccc4e1455447fac 195 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 9 186 7.0E-55 T 13-09-2016 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 MetaCyc: PWY-5964|MetaCyc: PWY-7639 THL1_RS10520 26280c9604833007cccc4e1455447fac 195 PANTHER PTHR19136 1 189 1.5E-41 T 13-09-2016 THL1_RS10520 26280c9604833007cccc4e1455447fac 195 SUPERFAMILY SSF53448 8 185 3.38E-32 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS10520 26280c9604833007cccc4e1455447fac 195 PANTHER PTHR19136:SF81 1 189 1.5E-41 T 13-09-2016 THL1_RS10520 26280c9604833007cccc4e1455447fac 195 Pfam PF12804 MobA-like NTP transferase domain 12 167 3.7E-30 T 13-09-2016 IPR025877 MobA-like NTP transferase THL1_RS10520 26280c9604833007cccc4e1455447fac 195 Gene3D G3DSA:3.90.550.10 8 186 2.2E-44 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS10520 26280c9604833007cccc4e1455447fac 195 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 7 191 23.47 T 13-09-2016 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 MetaCyc: PWY-5964|MetaCyc: PWY-7639 THL1_RS03060 62f0318c41742c72b2385123cec04256 356 PANTHER PTHR10366 4 355 4.8E-177 T 13-09-2016 THL1_RS03060 62f0318c41742c72b2385123cec04256 356 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 5 341 2.0E-156 T 13-09-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 THL1_RS03060 62f0318c41742c72b2385123cec04256 356 PANTHER PTHR10366:SF41 4 355 4.8E-177 T 13-09-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 THL1_RS03060 62f0318c41742c72b2385123cec04256 356 Gene3D G3DSA:3.90.25.10 194 344 3.6E-54 T 13-09-2016 THL1_RS03060 62f0318c41742c72b2385123cec04256 356 SUPERFAMILY SSF51735 1 340 4.81E-97 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS03060 62f0318c41742c72b2385123cec04256 356 Gene3D G3DSA:3.40.50.720 2 193 2.5E-68 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS03060 62f0318c41742c72b2385123cec04256 356 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 328 1.8E-98 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23660 59cae965936f7d24c9b167a77151d8ab 161 PANTHER PTHR10516:SF316 3 74 6.1E-41 T 13-09-2016 THL1_RS23660 59cae965936f7d24c9b167a77151d8ab 161 SUPERFAMILY SSF54534 3 141 6.29E-36 T 13-09-2016 THL1_RS23660 59cae965936f7d24c9b167a77151d8ab 161 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 6 136 5.4E-11 T 13-09-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 THL1_RS23660 59cae965936f7d24c9b167a77151d8ab 161 Gene3D G3DSA:3.10.50.40 123 143 1.7E-18 T 13-09-2016 THL1_RS23660 59cae965936f7d24c9b167a77151d8ab 161 Gene3D G3DSA:3.10.50.40 4 69 1.7E-18 T 13-09-2016 THL1_RS23660 59cae965936f7d24c9b167a77151d8ab 161 PANTHER PTHR10516:SF316 130 161 6.1E-41 T 13-09-2016 THL1_RS23660 59cae965936f7d24c9b167a77151d8ab 161 PANTHER PTHR10516 130 161 6.1E-41 T 13-09-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type THL1_RS23660 59cae965936f7d24c9b167a77151d8ab 161 PANTHER PTHR10516 3 74 6.1E-41 T 13-09-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type THL1_RS17480 d318903749359b8d4bf426a3569122be 163 Gene3D G3DSA:1.10.10.10 3 144 8.2E-30 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS17480 d318903749359b8d4bf426a3569122be 163 SUPERFAMILY SSF46785 11 146 7.4E-28 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS17480 d318903749359b8d4bf426a3569122be 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 9.2E-5 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS17480 d318903749359b8d4bf426a3569122be 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 9.2E-5 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS17480 d318903749359b8d4bf426a3569122be 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 9.2E-5 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS17480 d318903749359b8d4bf426a3569122be 163 PANTHER PTHR33164 13 154 1.7E-26 T 13-09-2016 THL1_RS17480 d318903749359b8d4bf426a3569122be 163 Pfam PF12802 MarR family 33 94 8.0E-9 T 13-09-2016 THL1_RS17480 d318903749359b8d4bf426a3569122be 163 SMART SM00347 27 130 1.6E-18 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS12865 2395ac75175299f38280eddf239edced 244 PANTHER PTHR11019 139 234 2.4E-13 T 13-09-2016 THL1_RS12865 2395ac75175299f38280eddf239edced 244 Pfam PF12833 Helix-turn-helix domain 161 236 2.1E-16 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS12865 2395ac75175299f38280eddf239edced 244 Gene3D G3DSA:1.10.10.60 199 235 7.9E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS12865 2395ac75175299f38280eddf239edced 244 SUPERFAMILY SSF46689 192 236 7.17E-7 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS12865 2395ac75175299f38280eddf239edced 244 Gene3D G3DSA:2.60.40.420 25 54 6.7E-4 T 13-09-2016 IPR008972 Cupredoxin THL1_RS12865 2395ac75175299f38280eddf239edced 244 SUPERFAMILY SSF49503 6 54 1.66E-5 T 13-09-2016 IPR008972 Cupredoxin THL1_RS12865 2395ac75175299f38280eddf239edced 244 Gene3D G3DSA:1.10.10.60 141 193 9.6E-6 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS12865 2395ac75175299f38280eddf239edced 244 SMART SM00342 155 237 5.3E-13 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS17930 9741e217e444e9d0b92c3a0efa689031 608 PANTHER PTHR30290 393 608 7.1E-208 T 13-09-2016 THL1_RS17930 9741e217e444e9d0b92c3a0efa689031 608 SUPERFAMILY SSF53850 48 603 1.85E-121 T 13-09-2016 THL1_RS17930 9741e217e444e9d0b92c3a0efa689031 608 PANTHER PTHR30290 1 368 7.1E-208 T 13-09-2016 THL1_RS17930 9741e217e444e9d0b92c3a0efa689031 608 PIRSF PIRSF002741 18 605 4.3E-105 T 13-09-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 THL1_RS17930 9741e217e444e9d0b92c3a0efa689031 608 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 112 516 2.3E-75 T 13-09-2016 IPR000914 Solute-binding protein family 5 domain THL1_RS17930 9741e217e444e9d0b92c3a0efa689031 608 PANTHER PTHR30290:SF2 393 608 7.1E-208 T 13-09-2016 THL1_RS17930 9741e217e444e9d0b92c3a0efa689031 608 Gene3D G3DSA:3.90.76.10 63 227 5.2E-35 T 13-09-2016 THL1_RS17930 9741e217e444e9d0b92c3a0efa689031 608 Gene3D G3DSA:3.10.105.10 319 572 2.9E-47 T 13-09-2016 THL1_RS17930 9741e217e444e9d0b92c3a0efa689031 608 PANTHER PTHR30290:SF2 1 368 7.1E-208 T 13-09-2016 THL1_RS10505 b4fc4dff091da7baa3b7b63395d30134 410 Gene3D G3DSA:1.10.443.10 217 386 3.6E-25 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS10505 b4fc4dff091da7baa3b7b63395d30134 410 Pfam PF13356 Domain of unknown function (DUF4102) 13 95 5.9E-15 T 13-09-2016 IPR025166 Domain of unknown function DUF4102 THL1_RS10505 b4fc4dff091da7baa3b7b63395d30134 410 Pfam PF00589 Phage integrase family 217 376 1.9E-21 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS10505 b4fc4dff091da7baa3b7b63395d30134 410 Gene3D G3DSA:1.10.150.130 107 203 4.6E-13 T 13-09-2016 IPR023109 Integrase/recombinase, N-terminal THL1_RS10505 b4fc4dff091da7baa3b7b63395d30134 410 PANTHER PTHR30629:SF3 5 401 2.5E-120 T 13-09-2016 THL1_RS10505 b4fc4dff091da7baa3b7b63395d30134 410 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 108 162 2.3E-5 T 13-09-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THL1_RS10505 b4fc4dff091da7baa3b7b63395d30134 410 SUPERFAMILY SSF56349 107 388 1.24E-60 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS10505 b4fc4dff091da7baa3b7b63395d30134 410 PANTHER PTHR30629 5 401 2.5E-120 T 13-09-2016 THL1_RS18365 12b03d9835ea8f7329e5f9c9b1917c9d 251 Pfam PF02517 CAAX protease self-immunity 150 238 2.0E-17 T 13-09-2016 IPR003675 CAAX amino terminal protease GO:0016020 THL1_RS18365 12b03d9835ea8f7329e5f9c9b1917c9d 251 PANTHER PTHR40041:SF2 7 250 1.9E-50 T 13-09-2016 THL1_RS18365 12b03d9835ea8f7329e5f9c9b1917c9d 251 PANTHER PTHR40041 7 250 1.9E-50 T 13-09-2016 THL1_RS01190 6ae4faf2ddb4d9cc88d32be5c0c60adb 451 Gene3D G3DSA:3.30.830.10 26 247 2.7E-58 T 13-09-2016 IPR011237 Peptidase M16 domain GO:0046872 THL1_RS01190 6ae4faf2ddb4d9cc88d32be5c0c60adb 451 SUPERFAMILY SSF63411 254 448 8.77E-35 T 13-09-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THL1_RS01190 6ae4faf2ddb4d9cc88d32be5c0c60adb 451 SUPERFAMILY SSF63411 28 245 7.52E-62 T 13-09-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THL1_RS01190 6ae4faf2ddb4d9cc88d32be5c0c60adb 451 Pfam PF05193 Peptidase M16 inactive domain 196 378 7.6E-28 T 13-09-2016 IPR007863 Peptidase M16, C-terminal THL1_RS01190 6ae4faf2ddb4d9cc88d32be5c0c60adb 451 Gene3D G3DSA:3.30.830.10 261 442 2.5E-25 T 13-09-2016 IPR011237 Peptidase M16 domain GO:0046872 THL1_RS01190 6ae4faf2ddb4d9cc88d32be5c0c60adb 451 PANTHER PTHR11851:SF136 30 437 1.9E-102 T 13-09-2016 THL1_RS01190 6ae4faf2ddb4d9cc88d32be5c0c60adb 451 PANTHER PTHR11851 30 437 1.9E-102 T 13-09-2016 THL1_RS01190 6ae4faf2ddb4d9cc88d32be5c0c60adb 451 Pfam PF00675 Insulinase (Peptidase family M16) 40 175 3.2E-21 T 13-09-2016 IPR011765 Peptidase M16, N-terminal THL1_RS12395 38ba740d5b91befbc048c99782950067 226 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 226 101.644 T 13-09-2016 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 THL1_RS12395 38ba740d5b91befbc048c99782950067 226 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 34 204 6.0E-77 T 13-09-2016 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 THL1_RS12395 38ba740d5b91befbc048c99782950067 226 SUPERFAMILY SSF55729 2 224 1.17E-94 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS12395 38ba740d5b91befbc048c99782950067 226 PANTHER PTHR30098:SF2 1 225 4.7E-79 T 13-09-2016 THL1_RS12395 38ba740d5b91befbc048c99782950067 226 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 31 214 3.0E-66 T 13-09-2016 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 THL1_RS12395 38ba740d5b91befbc048c99782950067 226 PANTHER PTHR30098 1 225 4.7E-79 T 13-09-2016 THL1_RS14190 95f4264c6c982070105cc40c86714a84 322 Pfam PF10282 Lactonase, 7-bladed beta-propeller 181 302 3.4E-6 T 13-09-2016 IPR019405 Lactonase, 7-bladed beta propeller KEGG: 00030+3.1.1.31|UniPathway: UPA00115 THL1_RS14190 95f4264c6c982070105cc40c86714a84 322 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 104 145 2.9E-9 T 13-09-2016 IPR011964 YVTN beta-propeller repeat THL1_RS14190 95f4264c6c982070105cc40c86714a84 322 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 280 321 1.1E-14 T 13-09-2016 IPR011964 YVTN beta-propeller repeat THL1_RS14190 95f4264c6c982070105cc40c86714a84 322 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 24 61 2.8E-9 T 13-09-2016 IPR011964 YVTN beta-propeller repeat THL1_RS14190 95f4264c6c982070105cc40c86714a84 322 PANTHER PTHR13833 25 185 2.3E-28 T 13-09-2016 THL1_RS14190 95f4264c6c982070105cc40c86714a84 322 PANTHER PTHR13833 278 320 2.3E-28 T 13-09-2016 THL1_RS14190 95f4264c6c982070105cc40c86714a84 322 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 48 - T 13-09-2016 IPR010916 TonB box, conserved site THL1_RS14190 95f4264c6c982070105cc40c86714a84 322 SUPERFAMILY SSF50974 5 322 1.57E-83 T 13-09-2016 IPR011045 Nitrous oxide reductase, N-terminal THL1_RS14190 95f4264c6c982070105cc40c86714a84 322 Gene3D G3DSA:2.130.10.10 22 322 1.6E-81 T 13-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THL1_RS14190 95f4264c6c982070105cc40c86714a84 322 TIGRFAM TIGR03866 PQQ_ABC_repeats: PQQ-dependent catabolism-associated beta-propeller protein 14 322 1.5E-163 T 13-09-2016 IPR022456 PQQ-dependent catabolism-associated beta-propeller protein THL1_RS14190 95f4264c6c982070105cc40c86714a84 322 Pfam PF02239 Cytochrome D1 heme domain 71 173 1.3E-7 T 13-09-2016 THL1_RS06020 68aab781eb54834b45a65077f152d353 121 Gene3D G3DSA:1.10.10.10 21 119 1.2E-43 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS06020 68aab781eb54834b45a65077f152d353 121 PANTHER PTHR33204:SF2 10 121 2.0E-52 T 13-09-2016 THL1_RS06020 68aab781eb54834b45a65077f152d353 121 SUPERFAMILY SSF46785 21 117 4.43E-33 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS06020 68aab781eb54834b45a65077f152d353 121 PANTHER PTHR33204 10 121 2.0E-52 T 13-09-2016 THL1_RS06020 68aab781eb54834b45a65077f152d353 121 Pfam PF01638 HxlR-like helix-turn-helix 31 119 1.1E-36 T 13-09-2016 IPR002577 Helix-turn-helix, HxlR type THL1_RS09975 c5a31b8983460fa812efda414770f00b 280 Gene3D G3DSA:3.40.50.1820 53 254 2.5E-29 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS09975 c5a31b8983460fa812efda414770f00b 280 PANTHER PTHR10992:SF107 2 268 3.1E-30 T 13-09-2016 THL1_RS09975 c5a31b8983460fa812efda414770f00b 280 PANTHER PTHR10992 2 268 3.1E-30 T 13-09-2016 THL1_RS09975 c5a31b8983460fa812efda414770f00b 280 SUPERFAMILY SSF53474 37 255 2.8E-31 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS09975 c5a31b8983460fa812efda414770f00b 280 Pfam PF12697 Alpha/beta hydrolase family 69 231 8.9E-10 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS08525 ec81fa672c22e5de8a87cb9f22e4e49b 255 Pfam PF00005 ABC transporter 22 181 1.1E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS08525 ec81fa672c22e5de8a87cb9f22e4e49b 255 Gene3D G3DSA:3.40.50.300 2 249 3.0E-67 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08525 ec81fa672c22e5de8a87cb9f22e4e49b 255 SMART SM00382 30 230 2.8E-9 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS08525 ec81fa672c22e5de8a87cb9f22e4e49b 255 PANTHER PTHR24220 121 254 6.3E-128 T 13-09-2016 THL1_RS08525 ec81fa672c22e5de8a87cb9f22e4e49b 255 PANTHER PTHR24220 7 105 6.3E-128 T 13-09-2016 THL1_RS08525 ec81fa672c22e5de8a87cb9f22e4e49b 255 SUPERFAMILY SSF52540 4 253 3.41E-63 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08525 ec81fa672c22e5de8a87cb9f22e4e49b 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 233 253 2.5E-11 T 13-09-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal THL1_RS08525 ec81fa672c22e5de8a87cb9f22e4e49b 255 PANTHER PTHR24220:SF358 121 254 6.3E-128 T 13-09-2016 THL1_RS08525 ec81fa672c22e5de8a87cb9f22e4e49b 255 PANTHER PTHR24220:SF358 7 105 6.3E-128 T 13-09-2016 THL1_RS08525 ec81fa672c22e5de8a87cb9f22e4e49b 255 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 SUPERFAMILY SSF55874 286 448 2.1E-37 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 4 447 4.2E-157 T 13-09-2016 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 SMART SM00387 339 449 3.9E-32 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 Gene3D G3DSA:1.10.287.130 220 292 1.6E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 Pfam PF00512 His Kinase A (phospho-acceptor) domain 231 296 8.5E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 PANTHER PTHR24423 21 135 1.4E-122 T 13-09-2016 THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 390 1.7E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 404 1.7E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 429 1.7E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 447 1.7E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 Pfam PF00672 HAMP domain 157 225 2.8E-12 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 340 447 2.6E-18 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 Gene3D G3DSA:3.30.565.10 300 448 9.5E-37 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 PANTHER PTHR24423:SF354 21 135 1.4E-122 T 13-09-2016 THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 PANTHER PTHR24423:SF354 170 447 1.4E-122 T 13-09-2016 THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 SMART SM00388 230 296 8.1E-17 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 SUPERFAMILY SSF47384 213 296 6.47E-18 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 SMART SM00304 176 229 5.3E-9 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 PANTHER PTHR24423 170 447 1.4E-122 T 13-09-2016 THL1_RS16725 a0a43e3f587d258aa490849ce104ad51 449 SUPERFAMILY SSF158472 177 226 8.63E-5 T 13-09-2016 THL1_RS11730 b82416da35985c0be413965137e0e08d 144 Pfam PF07681 DoxX 17 104 4.8E-23 T 13-09-2016 IPR032808 DoxX family THL1_RS11730 b82416da35985c0be413965137e0e08d 144 PANTHER PTHR33452 1 144 3.7E-40 T 13-09-2016 THL1_RS11730 b82416da35985c0be413965137e0e08d 144 PANTHER PTHR33452:SF1 1 144 3.7E-40 T 13-09-2016 THL1_RS07915 18232d62d80e692f64a80ee7ea287e88 442 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 274 - T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS07915 18232d62d80e692f64a80ee7ea287e88 442 Pfam PF00202 Aminotransferase class-III 16 435 1.6E-102 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS07915 18232d62d80e692f64a80ee7ea287e88 442 PANTHER PTHR11986 1 442 9.8E-200 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS07915 18232d62d80e692f64a80ee7ea287e88 442 SUPERFAMILY SSF53383 13 436 1.37E-122 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS07915 18232d62d80e692f64a80ee7ea287e88 442 Gene3D G3DSA:3.40.640.10 50 310 3.9E-85 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS07915 18232d62d80e692f64a80ee7ea287e88 442 PANTHER PTHR11986:SF78 1 442 9.8E-200 T 13-09-2016 THL1_RS07915 18232d62d80e692f64a80ee7ea287e88 442 Gene3D G3DSA:3.90.1150.10 311 436 2.0E-36 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS04880 a93ffe5b3216f550dedb2c751d6db834 171 SUPERFAMILY SSF54523 8 148 6.59E-14 T 13-09-2016 THL1_RS04880 a93ffe5b3216f550dedb2c751d6db834 171 Pfam PF12019 Type II transport protein GspH 45 159 4.1E-19 T 13-09-2016 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 THL1_RS04880 a93ffe5b3216f550dedb2c751d6db834 171 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 27 1.5E-4 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS24580 84420e367ab8b0477086a659f399c57c 345 SUPERFAMILY SSF53850 26 342 7.7E-82 T 13-09-2016 THL1_RS24580 84420e367ab8b0477086a659f399c57c 345 Gene3D G3DSA:3.40.190.10 144 284 1.8E-39 T 13-09-2016 THL1_RS24580 84420e367ab8b0477086a659f399c57c 345 PANTHER PTHR30222 7 344 1.7E-82 T 13-09-2016 THL1_RS24580 84420e367ab8b0477086a659f399c57c 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 74 88 1.4E-39 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS24580 84420e367ab8b0477086a659f399c57c 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 290 316 1.4E-39 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS24580 84420e367ab8b0477086a659f399c57c 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 165 184 1.4E-39 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS24580 84420e367ab8b0477086a659f399c57c 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 245 264 1.4E-39 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS24580 84420e367ab8b0477086a659f399c57c 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 47 68 1.4E-39 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS24580 84420e367ab8b0477086a659f399c57c 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 31 47 1.4E-39 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS24580 84420e367ab8b0477086a659f399c57c 345 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 121 137 1.4E-39 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS24580 84420e367ab8b0477086a659f399c57c 345 PANTHER PTHR30222:SF5 7 344 1.7E-82 T 13-09-2016 THL1_RS24580 84420e367ab8b0477086a659f399c57c 345 Gene3D G3DSA:3.40.190.10 27 143 6.0E-26 T 13-09-2016 THL1_RS24580 84420e367ab8b0477086a659f399c57c 345 Pfam PF13416 Bacterial extracellular solute-binding protein 41 311 5.6E-33 T 13-09-2016 THL1_RS24580 84420e367ab8b0477086a659f399c57c 345 PIRSF PIRSF019574 4 345 2.0E-98 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS06805 b333cd42ced78964e7fb4c4a1fe9ba2a 245 PRINTS PR01805 VacJ lipoprotein signature 152 169 2.9E-24 T 13-09-2016 IPR007428 MlaA lipoprotein GO:0016020 THL1_RS06805 b333cd42ced78964e7fb4c4a1fe9ba2a 245 PRINTS PR01805 VacJ lipoprotein signature 65 81 2.9E-24 T 13-09-2016 IPR007428 MlaA lipoprotein GO:0016020 THL1_RS06805 b333cd42ced78964e7fb4c4a1fe9ba2a 245 PRINTS PR01805 VacJ lipoprotein signature 116 133 2.9E-24 T 13-09-2016 IPR007428 MlaA lipoprotein GO:0016020 THL1_RS06805 b333cd42ced78964e7fb4c4a1fe9ba2a 245 PRINTS PR01805 VacJ lipoprotein signature 48 61 2.9E-24 T 13-09-2016 IPR007428 MlaA lipoprotein GO:0016020 THL1_RS06805 b333cd42ced78964e7fb4c4a1fe9ba2a 245 PANTHER PTHR30035:SF2 14 245 5.1E-115 T 13-09-2016 THL1_RS06805 b333cd42ced78964e7fb4c4a1fe9ba2a 245 Pfam PF04333 MlaA lipoprotein 47 240 7.5E-67 T 13-09-2016 IPR007428 MlaA lipoprotein GO:0016020 THL1_RS06805 b333cd42ced78964e7fb4c4a1fe9ba2a 245 PANTHER PTHR30035 14 245 5.1E-115 T 13-09-2016 IPR007428 MlaA lipoprotein GO:0016020 THL1_RS20155 a4c81573c216e331c189c2ceea2643cf 125 SUPERFAMILY SSF54909 1 115 1.02E-36 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS20155 a4c81573c216e331c189c2ceea2643cf 125 PANTHER PTHR35174:SF3 2 114 2.8E-46 T 13-09-2016 THL1_RS20155 a4c81573c216e331c189c2ceea2643cf 125 PANTHER PTHR35174 2 114 2.8E-46 T 13-09-2016 THL1_RS20155 a4c81573c216e331c189c2ceea2643cf 125 Gene3D G3DSA:3.30.70.1060 1 115 1.4E-38 T 13-09-2016 THL1_RS20155 a4c81573c216e331c189c2ceea2643cf 125 Pfam PF03795 YCII-related domain 1 114 6.1E-28 T 13-09-2016 IPR005545 YCII-related THL1_RS07175 928cf56e03dd51fcbeafa4ce83870eb6 195 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 19 165 24.051 T 13-09-2016 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 THL1_RS07175 928cf56e03dd51fcbeafa4ce83870eb6 195 SUPERFAMILY SSF64438 24 167 3.84E-34 T 13-09-2016 IPR011324 Cytotoxic necrotizing factor-like, catalytic THL1_RS07175 928cf56e03dd51fcbeafa4ce83870eb6 195 Pfam PF03975 CheD chemotactic sensory transduction 72 161 1.2E-19 T 13-09-2016 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 THL1_RS07175 928cf56e03dd51fcbeafa4ce83870eb6 195 PANTHER PTHR35147 13 193 3.4E-58 T 13-09-2016 THL1_RS07175 928cf56e03dd51fcbeafa4ce83870eb6 195 PANTHER PTHR35147:SF2 13 193 3.4E-58 T 13-09-2016 THL1_RS18640 10e601a783bde47ceca457232059f92d 414 Gene3D G3DSA:3.40.47.10 263 412 7.1E-67 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS18640 10e601a783bde47ceca457232059f92d 414 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 410 1.8E-197 T 13-09-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 THL1_RS18640 10e601a783bde47ceca457232059f92d 414 SMART SM00825 Beta-ketoacyl synthase 6 414 2.4E-15 T 13-09-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain THL1_RS18640 10e601a783bde47ceca457232059f92d 414 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 369 4.2E-40 T 13-09-2016 IPR014031 Beta-ketoacyl synthase, C-terminal THL1_RS18640 10e601a783bde47ceca457232059f92d 414 PANTHER PTHR11712 3 412 1.7E-218 T 13-09-2016 THL1_RS18640 10e601a783bde47ceca457232059f92d 414 SUPERFAMILY SSF53901 4 252 1.51E-77 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS18640 10e601a783bde47ceca457232059f92d 414 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 247 9.8E-60 T 13-09-2016 IPR014030 Beta-ketoacyl synthase, N-terminal THL1_RS18640 10e601a783bde47ceca457232059f92d 414 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 13-09-2016 IPR018201 Beta-ketoacyl synthase, active site THL1_RS18640 10e601a783bde47ceca457232059f92d 414 Gene3D G3DSA:3.40.47.10 3 260 5.7E-76 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS18640 10e601a783bde47ceca457232059f92d 414 PIRSF PIRSF000447 1 414 3.5E-192 T 13-09-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 THL1_RS18640 10e601a783bde47ceca457232059f92d 414 SUPERFAMILY SSF53901 214 412 6.64E-76 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS03660 4eee562b6b913330bd3d3b27d7a6cb0b 481 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 334 342 - T 13-09-2016 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS03660 4eee562b6b913330bd3d3b27d7a6cb0b 481 Gene3D G3DSA:2.40.180.10 3 358 1.7E-171 T 13-09-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS03660 4eee562b6b913330bd3d3b27d7a6cb0b 481 Pfam PF00199 Catalase 8 390 1.5E-184 T 13-09-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS03660 4eee562b6b913330bd3d3b27d7a6cb0b 481 SUPERFAMILY SSF56634 3 478 9.42E-206 T 13-09-2016 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS03660 4eee562b6b913330bd3d3b27d7a6cb0b 481 SMART SM01060 8 393 1.1E-274 T 13-09-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS03660 4eee562b6b913330bd3d3b27d7a6cb0b 481 PRINTS PR00067 Catalase signature 21 44 8.7E-71 T 13-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS03660 4eee562b6b913330bd3d3b27d7a6cb0b 481 PRINTS PR00067 Catalase signature 84 102 8.7E-71 T 13-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS03660 4eee562b6b913330bd3d3b27d7a6cb0b 481 PRINTS PR00067 Catalase signature 124 142 8.7E-71 T 13-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS03660 4eee562b6b913330bd3d3b27d7a6cb0b 481 PRINTS PR00067 Catalase signature 105 122 8.7E-71 T 13-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS03660 4eee562b6b913330bd3d3b27d7a6cb0b 481 PRINTS PR00067 Catalase signature 289 316 8.7E-71 T 13-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS03660 4eee562b6b913330bd3d3b27d7a6cb0b 481 PRINTS PR00067 Catalase signature 321 347 8.7E-71 T 13-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS03660 4eee562b6b913330bd3d3b27d7a6cb0b 481 PIRSF PIRSF038928 1 481 3.3E-219 T 13-09-2016 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS03660 4eee562b6b913330bd3d3b27d7a6cb0b 481 PANTHER PTHR11465 3 477 2.8E-277 T 13-09-2016 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS03660 4eee562b6b913330bd3d3b27d7a6cb0b 481 Pfam PF06628 Catalase-related immune-responsive 417 477 1.5E-21 T 13-09-2016 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS23130 1389f26afac789f082d5cdab6b73e78c 184 Pfam PF14803 Nudix N-terminal 2 35 6.3E-19 T 13-09-2016 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.-+3.6.1.13|KEGG: 00332+3.6.1.-|KEGG: 00740+3.6.1.18|KEGG: 00790+3.6.1.- THL1_RS23130 1389f26afac789f082d5cdab6b73e78c 184 Gene3D G3DSA:2.20.70.10 1 35 3.7E-21 T 13-09-2016 THL1_RS23130 1389f26afac789f082d5cdab6b73e78c 184 Gene3D G3DSA:3.90.79.10 36 164 1.9E-34 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS23130 1389f26afac789f082d5cdab6b73e78c 184 Pfam PF00293 NUDIX domain 38 141 6.0E-15 T 13-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 THL1_RS23130 1389f26afac789f082d5cdab6b73e78c 184 PRINTS PR00502 NUDIX hydrolase family signature 79 94 6.3E-5 T 13-09-2016 IPR020476 NUDIX hydrolase THL1_RS23130 1389f26afac789f082d5cdab6b73e78c 184 PRINTS PR00502 NUDIX hydrolase family signature 65 79 6.3E-5 T 13-09-2016 IPR020476 NUDIX hydrolase THL1_RS23130 1389f26afac789f082d5cdab6b73e78c 184 PANTHER PTHR22769 1 179 8.7E-90 T 13-09-2016 THL1_RS23130 1389f26afac789f082d5cdab6b73e78c 184 SUPERFAMILY SSF55811 2 161 5.28E-40 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS23130 1389f26afac789f082d5cdab6b73e78c 184 PANTHER PTHR22769:SF17 1 179 8.7E-90 T 13-09-2016 THL1_RS14360 4a3b3fd5563361c7a16dd6334ce3142b 201 PANTHER PTHR33711 1 201 9.7E-82 T 13-09-2016 THL1_RS14360 4a3b3fd5563361c7a16dd6334ce3142b 201 PANTHER PTHR33711:SF2 1 201 9.7E-82 T 13-09-2016 THL1_RS14360 4a3b3fd5563361c7a16dd6334ce3142b 201 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 52 80 - T 13-09-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 THL1_RS14360 4a3b3fd5563361c7a16dd6334ce3142b 201 Gene3D G3DSA:2.60.130.10 4 201 2.3E-65 T 13-09-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 THL1_RS14360 4a3b3fd5563361c7a16dd6334ce3142b 201 Pfam PF00775 Dioxygenase 30 191 1.1E-12 T 13-09-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 THL1_RS14360 4a3b3fd5563361c7a16dd6334ce3142b 201 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 9 201 1.6E-74 T 13-09-2016 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|UniPathway: UPA00157 THL1_RS14360 4a3b3fd5563361c7a16dd6334ce3142b 201 SUPERFAMILY SSF49482 4 201 1.83E-57 T 13-09-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 THL1_RS20175 ffb96ddeced7622bee456976e7bb833b 106 PANTHER PTHR37811:SF2 1 103 5.8E-37 T 13-09-2016 THL1_RS20175 ffb96ddeced7622bee456976e7bb833b 106 SUPERFAMILY SSF54909 2 104 2.93E-34 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS20175 ffb96ddeced7622bee456976e7bb833b 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 11 83 2.1E-7 T 13-09-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain THL1_RS20175 ffb96ddeced7622bee456976e7bb833b 106 PANTHER PTHR37811 1 103 5.8E-37 T 13-09-2016 THL1_RS20175 ffb96ddeced7622bee456976e7bb833b 106 Gene3D G3DSA:3.30.70.900 19 104 1.8E-16 T 13-09-2016 THL1_RS00950 95e8b4582dd063a34a778a49358afed5 214 PANTHER PTHR30055 4 213 3.2E-43 T 13-09-2016 THL1_RS00950 95e8b4582dd063a34a778a49358afed5 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 1.0E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS00950 95e8b4582dd063a34a778a49358afed5 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 1.0E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS00950 95e8b4582dd063a34a778a49358afed5 214 Gene3D G3DSA:1.10.357.10 19 198 7.4E-21 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS00950 95e8b4582dd063a34a778a49358afed5 214 SUPERFAMILY SSF46689 11 81 8.74E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS00950 95e8b4582dd063a34a778a49358afed5 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 4.5E-10 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS00950 95e8b4582dd063a34a778a49358afed5 214 PANTHER PTHR30055:SF92 4 213 3.2E-43 T 13-09-2016 THL1_RS00115 cd11c8c9210f51f4e7085baabaf1a8e2 364 Pfam PF02481 DNA recombination-mediator protein A 76 283 3.9E-76 T 13-09-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 THL1_RS00115 cd11c8c9210f51f4e7085baabaf1a8e2 364 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 74 292 3.0E-77 T 13-09-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 THL1_RS00115 cd11c8c9210f51f4e7085baabaf1a8e2 364 Gene3D G3DSA:3.40.50.450 116 295 1.7E-13 T 13-09-2016 THL1_RS00115 cd11c8c9210f51f4e7085baabaf1a8e2 364 PANTHER PTHR32039:SF8 60 363 9.4E-106 T 13-09-2016 THL1_RS00115 cd11c8c9210f51f4e7085baabaf1a8e2 364 SUPERFAMILY SSF102405 85 293 1.04E-44 T 13-09-2016 THL1_RS00115 cd11c8c9210f51f4e7085baabaf1a8e2 364 PANTHER PTHR32039 60 363 9.4E-106 T 13-09-2016 THL1_RS13715 b060370c87ba008e607ba8f15c9ef9a9 486 PANTHER PTHR11699 1 484 1.4E-269 T 13-09-2016 THL1_RS13715 b060370c87ba008e607ba8f15c9ef9a9 486 Gene3D G3DSA:3.40.309.10 256 447 3.1E-72 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS13715 b060370c87ba008e607ba8f15c9ef9a9 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 241 248 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS13715 b060370c87ba008e607ba8f15c9ef9a9 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 269 280 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS13715 b060370c87ba008e607ba8f15c9ef9a9 486 Pfam PF00171 Aldehyde dehydrogenase family 13 472 3.6E-174 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS13715 b060370c87ba008e607ba8f15c9ef9a9 486 Gene3D G3DSA:3.40.605.10 2 255 2.5E-98 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS13715 b060370c87ba008e607ba8f15c9ef9a9 486 SUPERFAMILY SSF53720 2 478 6.54E-169 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS13715 b060370c87ba008e607ba8f15c9ef9a9 486 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 2 485 1.1E-221 T 13-09-2016 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 KEGG: 00010+1.2.1.-|KEGG: 00220+1.2.1.-|KEGG: 00260+1.2.1.-|KEGG: 00281+1.2.1.-|KEGG: 00300+1.2.1.-|KEGG: 00330+1.2.1.-|KEGG: 00380+1.2.1.-|KEGG: 00620+1.2.1.-|KEGG: 00624+1.2.1.-|KEGG: 00626+1.2.1.-|KEGG: 00640+1.2.1.-|KEGG: 00903+1.2.1.-|UniPathway: UPA00208 THL1_RS13715 b060370c87ba008e607ba8f15c9ef9a9 486 PANTHER PTHR11699:SF213 1 484 1.4E-269 T 13-09-2016 THL1_RS19640 830ff7ac1644bac6fbe3507b76cd59bc 126 PIRSF PIRSF039090 1 126 2.0E-44 T 13-09-2016 IPR003713 Flagellar protein FliS GO:0044780 THL1_RS19640 830ff7ac1644bac6fbe3507b76cd59bc 126 Pfam PF02561 Flagellar protein FliS 8 124 3.4E-38 T 13-09-2016 IPR003713 Flagellar protein FliS GO:0044780 THL1_RS19640 830ff7ac1644bac6fbe3507b76cd59bc 126 TIGRFAM TIGR00208 fliS: flagellar protein FliS 4 124 1.1E-27 T 13-09-2016 IPR003713 Flagellar protein FliS GO:0044780 THL1_RS19640 830ff7ac1644bac6fbe3507b76cd59bc 126 PANTHER PTHR34773 1 126 2.7E-40 T 13-09-2016 THL1_RS19640 830ff7ac1644bac6fbe3507b76cd59bc 126 Gene3D G3DSA:1.20.120.340 8 125 9.6E-41 T 13-09-2016 IPR003713 Flagellar protein FliS GO:0044780 THL1_RS19640 830ff7ac1644bac6fbe3507b76cd59bc 126 SUPERFAMILY SSF101116 8 125 3.27E-39 T 13-09-2016 IPR003713 Flagellar protein FliS GO:0044780 THL1_RS16250 e81fae4469358063e7ce1550e76b017a 134 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 3 44 4.1E-13 T 13-09-2016 IPR022453 Zinc finger, MqsA-type THL1_RS16250 e81fae4469358063e7ce1550e76b017a 134 PANTHER PTHR36511:SF3 2 30 1.1E-20 T 13-09-2016 THL1_RS16250 e81fae4469358063e7ce1550e76b017a 134 SMART SM00530 73 127 2.1E-5 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS16250 e81fae4469358063e7ce1550e76b017a 134 TIGRFAM TIGR03830 CxxCG_CxxCG_HTH: putative zinc finger/helix-turn-helix protein, YgiT family 3 130 2.5E-41 T 13-09-2016 IPR022452 Antitoxin MqsA THL1_RS16250 e81fae4469358063e7ce1550e76b017a 134 Gene3D G3DSA:1.10.260.40 72 125 1.4E-7 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS16250 e81fae4469358063e7ce1550e76b017a 134 PANTHER PTHR36511 58 131 1.1E-20 T 13-09-2016 THL1_RS16250 e81fae4469358063e7ce1550e76b017a 134 PANTHER PTHR36511:SF3 58 131 1.1E-20 T 13-09-2016 THL1_RS16250 e81fae4469358063e7ce1550e76b017a 134 Pfam PF15731 Antitoxin component of bacterial toxin-antitoxin system, MqsA 1 131 1.4E-50 T 13-09-2016 IPR032758 Antitoxin MqsA/igA-2 THL1_RS16250 e81fae4469358063e7ce1550e76b017a 134 PANTHER PTHR36511 2 30 1.1E-20 T 13-09-2016 THL1_RS16250 e81fae4469358063e7ce1550e76b017a 134 SUPERFAMILY SSF47413 71 124 8.19E-9 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS16560 dc78934fdcb351019956f9bf087e1ec7 547 PANTHER PTHR18968:SF129 3 544 6.1E-301 T 13-09-2016 THL1_RS16560 dc78934fdcb351019956f9bf087e1ec7 547 SUPERFAMILY SSF52518 356 540 1.72E-56 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS16560 dc78934fdcb351019956f9bf087e1ec7 547 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 169 2.9E-53 T 13-09-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 THL1_RS16560 dc78934fdcb351019956f9bf087e1ec7 547 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 416 435 - T 13-09-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 THL1_RS16560 dc78934fdcb351019956f9bf087e1ec7 547 Gene3D G3DSA:3.40.50.1220 179 330 6.4E-38 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS16560 dc78934fdcb351019956f9bf087e1ec7 547 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 187 319 8.4E-31 T 13-09-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 THL1_RS16560 dc78934fdcb351019956f9bf087e1ec7 547 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 379 525 3.8E-37 T 13-09-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THL1_RS16560 dc78934fdcb351019956f9bf087e1ec7 547 SUPERFAMILY SSF52467 154 336 2.45E-39 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS16560 dc78934fdcb351019956f9bf087e1ec7 547 PANTHER PTHR18968 3 544 6.1E-301 T 13-09-2016 THL1_RS16560 dc78934fdcb351019956f9bf087e1ec7 547 Gene3D G3DSA:3.40.50.970 3 178 1.4E-66 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS16560 dc78934fdcb351019956f9bf087e1ec7 547 SUPERFAMILY SSF52518 3 180 8.61E-49 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS16560 dc78934fdcb351019956f9bf087e1ec7 547 Gene3D G3DSA:3.40.50.970 351 537 5.7E-55 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS13945 d9cbbf7cbf84ea3c8984598d8bf64f0f 841 SUPERFAMILY SSF82866 657 808 7.59E-31 T 13-09-2016 THL1_RS13945 d9cbbf7cbf84ea3c8984598d8bf64f0f 841 PANTHER PTHR33406 152 839 4.1E-87 T 13-09-2016 THL1_RS13945 d9cbbf7cbf84ea3c8984598d8bf64f0f 841 SUPERFAMILY SSF82866 251 414 2.62E-26 T 13-09-2016 THL1_RS13945 d9cbbf7cbf84ea3c8984598d8bf64f0f 841 PANTHER PTHR33406:SF2 12 117 4.1E-87 T 13-09-2016 THL1_RS13945 d9cbbf7cbf84ea3c8984598d8bf64f0f 841 PANTHER PTHR33406 12 117 4.1E-87 T 13-09-2016 THL1_RS13945 d9cbbf7cbf84ea3c8984598d8bf64f0f 841 Pfam PF03176 MMPL family 629 810 1.7E-11 T 13-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 THL1_RS13945 d9cbbf7cbf84ea3c8984598d8bf64f0f 841 Pfam PF03176 MMPL family 236 419 1.8E-5 T 13-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 THL1_RS13945 d9cbbf7cbf84ea3c8984598d8bf64f0f 841 PANTHER PTHR33406:SF2 152 839 4.1E-87 T 13-09-2016 THL1_RS13945 d9cbbf7cbf84ea3c8984598d8bf64f0f 841 Gene3D G3DSA:1.20.1640.10 246 421 4.2E-25 T 13-09-2016 THL1_RS13945 d9cbbf7cbf84ea3c8984598d8bf64f0f 841 Gene3D G3DSA:1.20.1640.10 654 808 3.1E-25 T 13-09-2016 THL1_RS27770 7ab51bf18cd88ae15eed146fd8464b51 432 SUPERFAMILY SSF51905 1 54 1.55E-51 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27770 7ab51bf18cd88ae15eed146fd8464b51 432 SUPERFAMILY SSF51905 360 417 1.55E-51 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27770 7ab51bf18cd88ae15eed146fd8464b51 432 SUPERFAMILY SSF51905 107 270 1.55E-51 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27770 7ab51bf18cd88ae15eed146fd8464b51 432 PANTHER PTHR13847:SF148 1 63 3.0E-240 T 13-09-2016 THL1_RS27770 7ab51bf18cd88ae15eed146fd8464b51 432 PANTHER PTHR13847:SF148 107 422 3.0E-240 T 13-09-2016 THL1_RS27770 7ab51bf18cd88ae15eed146fd8464b51 432 SUPERFAMILY SSF54373 270 360 4.45E-18 T 13-09-2016 THL1_RS27770 7ab51bf18cd88ae15eed146fd8464b51 432 Gene3D G3DSA:3.40.50.720 354 416 7.8E-47 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS27770 7ab51bf18cd88ae15eed146fd8464b51 432 Gene3D G3DSA:3.40.50.720 1 96 7.8E-47 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS27770 7ab51bf18cd88ae15eed146fd8464b51 432 Gene3D G3DSA:3.40.50.720 194 268 7.8E-47 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS27770 7ab51bf18cd88ae15eed146fd8464b51 432 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 411 48.902 T 13-09-2016 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 UniPathway: UPA00043 THL1_RS27770 7ab51bf18cd88ae15eed146fd8464b51 432 Pfam PF01266 FAD dependent oxidoreductase 3 398 1.1E-65 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS27770 7ab51bf18cd88ae15eed146fd8464b51 432 PANTHER PTHR13847 1 63 3.0E-240 T 13-09-2016 THL1_RS27770 7ab51bf18cd88ae15eed146fd8464b51 432 PANTHER PTHR13847 107 422 3.0E-240 T 13-09-2016 THL1_RS27770 7ab51bf18cd88ae15eed146fd8464b51 432 Gene3D G3DSA:3.30.9.10 269 353 1.5E-13 T 13-09-2016 THL1_RS27770 7ab51bf18cd88ae15eed146fd8464b51 432 Gene3D G3DSA:3.30.9.10 136 193 1.5E-13 T 13-09-2016 THL1_RS21270 5e019cb49811ae9e6969893ce884dc8e 247 PIRSF PIRSF006325 2 247 1.4E-105 T 13-09-2016 IPR005271 tRNA (cmo5U34)-methyltransferase GO:0002098|GO:0016300 THL1_RS21270 5e019cb49811ae9e6969893ce884dc8e 247 Pfam PF13649 Methyltransferase domain 63 163 1.5E-10 T 13-09-2016 THL1_RS21270 5e019cb49811ae9e6969893ce884dc8e 247 PANTHER PTHR10108:SF809 6 246 4.4E-88 T 13-09-2016 THL1_RS21270 5e019cb49811ae9e6969893ce884dc8e 247 Gene3D G3DSA:3.40.50.150 21 245 5.9E-54 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS21270 5e019cb49811ae9e6969893ce884dc8e 247 PANTHER PTHR10108 6 246 4.4E-88 T 13-09-2016 THL1_RS21270 5e019cb49811ae9e6969893ce884dc8e 247 SUPERFAMILY SSF53335 21 245 2.32E-34 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS21270 5e019cb49811ae9e6969893ce884dc8e 247 Hamap MF_01589 tRNA (cmo5U34)-methyltransferase [cmoA]. 4 247 38.86 T 13-09-2016 IPR005271 tRNA (cmo5U34)-methyltransferase GO:0002098|GO:0016300 THL1_RS21270 5e019cb49811ae9e6969893ce884dc8e 247 TIGRFAM TIGR00740 TIGR00740: tRNA (cmo5U34)-methyltransferase 6 246 1.2E-85 T 13-09-2016 IPR005271 tRNA (cmo5U34)-methyltransferase GO:0002098|GO:0016300 THL1_RS20890 9affaf7e15e9cb21114583e2c1f11414 403 Gene3D G3DSA:3.40.50.10540 5 212 1.4E-64 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS20890 9affaf7e15e9cb21114583e2c1f11414 403 Gene3D G3DSA:3.40.50.10540 307 400 1.4E-64 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS20890 9affaf7e15e9cb21114583e2c1f11414 403 Pfam PF02515 CoA-transferase family III 6 376 1.7E-63 T 13-09-2016 IPR003673 CoA-transferase family III GO:0003824 THL1_RS20890 9affaf7e15e9cb21114583e2c1f11414 403 Gene3D G3DSA:3.30.1540.10 232 306 5.2E-8 T 13-09-2016 THL1_RS20890 9affaf7e15e9cb21114583e2c1f11414 403 SUPERFAMILY SSF89796 5 400 6.41E-78 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS19240 b0924613c96164274912471520296b92 262 Gene3D G3DSA:1.10.10.10 87 163 5.7E-34 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19240 b0924613c96164274912471520296b92 262 SUPERFAMILY SSF46785 6 86 2.99E-15 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19240 b0924613c96164274912471520296b92 262 PANTHER PTHR34298 1 254 9.5E-77 T 13-09-2016 THL1_RS19240 b0924613c96164274912471520296b92 262 SUPERFAMILY SSF46785 87 163 1.22E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19240 b0924613c96164274912471520296b92 262 Gene3D G3DSA:1.10.10.10 5 85 3.1E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19240 b0924613c96164274912471520296b92 262 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 9 174 2.7E-34 T 13-09-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 THL1_RS19240 b0924613c96164274912471520296b92 262 Pfam PF04079 Segregation and condensation complex subunit ScpB 12 172 2.6E-50 T 13-09-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 THL1_RS19240 b0924613c96164274912471520296b92 262 PANTHER PTHR34298:SF2 1 254 9.5E-77 T 13-09-2016 THL1_RS07385 a44b2465d57904cf499aa1d56074d650 299 Pfam PF01522 Polysaccharide deacetylase 47 151 2.7E-14 T 13-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 THL1_RS07385 a44b2465d57904cf499aa1d56074d650 299 PANTHER PTHR10587 46 154 2.2E-20 T 13-09-2016 THL1_RS07385 a44b2465d57904cf499aa1d56074d650 299 Gene3D G3DSA:3.20.20.370 5 277 1.6E-65 T 13-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 THL1_RS07385 a44b2465d57904cf499aa1d56074d650 299 SUPERFAMILY SSF88713 5 278 5.38E-57 T 13-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THL1_RS11800 798e8e7768d33b28fb92e0237a7eba35 357 PANTHER PTHR21225 1 350 2.5E-217 T 13-09-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 THL1_RS11800 798e8e7768d33b28fb92e0237a7eba35 357 Gene3D G3DSA:3.20.20.70 11 352 5.8E-148 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS11800 798e8e7768d33b28fb92e0237a7eba35 357 SUPERFAMILY SSF51569 8 349 1.74E-134 T 13-09-2016 THL1_RS11800 798e8e7768d33b28fb92e0237a7eba35 357 PIRSF PIRSF001361 1 355 3.1E-157 T 13-09-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 THL1_RS11800 798e8e7768d33b28fb92e0237a7eba35 357 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 7 349 2.7E-150 T 13-09-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 THL1_RS11800 798e8e7768d33b28fb92e0237a7eba35 357 Pfam PF00793 DAHP synthetase I family 45 341 4.4E-94 T 13-09-2016 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 THL1_RS09275 13ad349f0853c1dd844ddb19d8a92d9d 459 Pfam PF00474 Sodium:solute symporter family 32 412 7.2E-36 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS09275 13ad349f0853c1dd844ddb19d8a92d9d 459 PANTHER PTHR11819 1 453 7.6E-174 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS09275 13ad349f0853c1dd844ddb19d8a92d9d 459 PANTHER PTHR11819:SF141 1 453 7.6E-174 T 13-09-2016 THL1_RS06530 12ff39324de6b8abfe9a991116d91d27 585 Gene3D G3DSA:3.50.50.60 4 163 1.8E-68 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS06530 12ff39324de6b8abfe9a991116d91d27 585 Gene3D G3DSA:3.50.50.60 214 321 1.8E-68 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS06530 12ff39324de6b8abfe9a991116d91d27 585 Gene3D G3DSA:3.50.50.60 504 565 1.8E-68 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS06530 12ff39324de6b8abfe9a991116d91d27 585 SUPERFAMILY SSF51905 507 565 4.52E-45 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS06530 12ff39324de6b8abfe9a991116d91d27 585 SUPERFAMILY SSF51905 223 334 4.52E-45 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS06530 12ff39324de6b8abfe9a991116d91d27 585 SUPERFAMILY SSF51905 5 150 4.52E-45 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS06530 12ff39324de6b8abfe9a991116d91d27 585 Gene3D G3DSA:3.90.700.10 338 498 8.0E-35 T 13-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain THL1_RS06530 12ff39324de6b8abfe9a991116d91d27 585 PANTHER PTHR11632 209 568 8.4E-164 T 13-09-2016 THL1_RS06530 12ff39324de6b8abfe9a991116d91d27 585 PANTHER PTHR11632 1 136 8.4E-164 T 13-09-2016 THL1_RS06530 12ff39324de6b8abfe9a991116d91d27 585 SUPERFAMILY SSF56425 341 508 1.36E-33 T 13-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain THL1_RS06530 12ff39324de6b8abfe9a991116d91d27 585 PANTHER PTHR11632:SF59 209 568 8.4E-164 T 13-09-2016 THL1_RS06530 12ff39324de6b8abfe9a991116d91d27 585 PANTHER PTHR11632:SF59 1 136 8.4E-164 T 13-09-2016 THL1_RS06530 12ff39324de6b8abfe9a991116d91d27 585 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 1.2E-8 T 13-09-2016 THL1_RS06530 12ff39324de6b8abfe9a991116d91d27 585 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 524 539 1.2E-8 T 13-09-2016 THL1_RS06530 12ff39324de6b8abfe9a991116d91d27 585 Pfam PF00890 FAD binding domain 13 549 6.9E-92 T 13-09-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain THL1_RS12360 983fe38ce63fa2186330183225c9c2a6 742 SUPERFAMILY SSF53659 4 740 0.0 T 13-09-2016 THL1_RS12360 983fe38ce63fa2186330183225c9c2a6 742 Pfam PF03971 Monomeric isocitrate dehydrogenase 6 738 0.0 T 13-09-2016 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 THL1_RS12360 983fe38ce63fa2186330183225c9c2a6 742 PANTHER PTHR36999 1 742 0.0 T 13-09-2016 THL1_RS12360 983fe38ce63fa2186330183225c9c2a6 742 Gene3D G3DSA:3.40.718.10 186 287 1.8E-31 T 13-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 THL1_RS12360 983fe38ce63fa2186330183225c9c2a6 742 Gene3D G3DSA:3.40.718.10 538 645 1.8E-31 T 13-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 THL1_RS12360 983fe38ce63fa2186330183225c9c2a6 742 Gene3D G3DSA:3.40.718.10 339 362 1.8E-31 T 13-09-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 THL1_RS12360 983fe38ce63fa2186330183225c9c2a6 742 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 3 740 0.0 T 13-09-2016 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 THL1_RS12360 983fe38ce63fa2186330183225c9c2a6 742 PIRSF PIRSF009407 1 741 0.0 T 13-09-2016 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 THL1_RS18205 bf25c377529d43b9ed9a350644f4cc1f 328 Gene3D G3DSA:3.30.470.20 238 290 6.7E-6 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS18205 bf25c377529d43b9ed9a350644f4cc1f 328 Gene3D G3DSA:3.30.470.20 162 201 8.1E-4 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS18205 bf25c377529d43b9ed9a350644f4cc1f 328 Gene3D G3DSA:3.30.470.20 40 101 7.4E-5 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS18205 bf25c377529d43b9ed9a350644f4cc1f 328 Pfam PF14397 Sugar-transfer associated ATP-grasp 21 294 1.0E-103 T 13-09-2016 THL1_RS18205 bf25c377529d43b9ed9a350644f4cc1f 328 SUPERFAMILY SSF56059 42 202 1.83E-19 T 13-09-2016 THL1_RS18205 bf25c377529d43b9ed9a350644f4cc1f 328 SUPERFAMILY SSF56059 232 282 1.83E-19 T 13-09-2016 THL1_RS18205 bf25c377529d43b9ed9a350644f4cc1f 328 TIGRFAM TIGR02291 rimK_rel_E_lig: alpha-L-glutamate ligase homolog 6 323 5.7E-171 T 13-09-2016 IPR011758 Alpha-L-glutamate ligase-related protein THL1_RS12940 deb28fc1f30eaab295b10e0ec6370191 156 SUPERFAMILY SSF52788 1 136 1.01E-36 T 13-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily THL1_RS12940 deb28fc1f30eaab295b10e0ec6370191 156 SMART SM00226 1 136 2.1E-36 T 13-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily THL1_RS12940 deb28fc1f30eaab295b10e0ec6370191 156 PANTHER PTHR11717:SF18 1 153 3.7E-32 T 13-09-2016 THL1_RS12940 deb28fc1f30eaab295b10e0ec6370191 156 Gene3D G3DSA:3.40.50.270 1 134 7.5E-36 T 13-09-2016 THL1_RS12940 deb28fc1f30eaab295b10e0ec6370191 156 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 134 3.4E-21 T 13-09-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily THL1_RS12940 deb28fc1f30eaab295b10e0ec6370191 156 PANTHER PTHR11717 1 153 3.7E-32 T 13-09-2016 THL1_RS24980 6f5a2cb66f3c361fd76f4588b72068fb 499 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 32 215 2.5E-35 T 13-09-2016 IPR004302 Chitin-binding protein, N-terminal THL1_RS24980 6f5a2cb66f3c361fd76f4588b72068fb 499 PANTHER PTHR34823 1 499 1.9E-121 T 13-09-2016 THL1_RS24980 6f5a2cb66f3c361fd76f4588b72068fb 499 PANTHER PTHR34823:SF1 1 499 1.9E-121 T 13-09-2016 THL1_RS24980 6f5a2cb66f3c361fd76f4588b72068fb 499 Gene3D G3DSA:2.70.50.50 32 218 4.9E-59 T 13-09-2016 THL1_RS24980 6f5a2cb66f3c361fd76f4588b72068fb 499 SUPERFAMILY SSF81296 32 219 8.12E-53 T 13-09-2016 IPR014756 Immunoglobulin E-set THL1_RS25010 3eff66aede5d8a8f7a7bcb0f3c32d887 144 Gene3D G3DSA:3.30.700.10 10 74 1.1E-10 T 13-09-2016 THL1_RS25010 3eff66aede5d8a8f7a7bcb0f3c32d887 144 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 8 143 1.1E-57 T 13-09-2016 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 THL1_RS25010 3eff66aede5d8a8f7a7bcb0f3c32d887 144 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 30 1.5E-9 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS25010 3eff66aede5d8a8f7a7bcb0f3c32d887 144 SUPERFAMILY SSF54523 36 143 5.76E-37 T 13-09-2016 THL1_RS25010 3eff66aede5d8a8f7a7bcb0f3c32d887 144 Pfam PF13633 Prokaryotic N-terminal methylation site 7 31 4.7E-10 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS25010 3eff66aede5d8a8f7a7bcb0f3c32d887 144 Pfam PF08334 Type II secretion system (T2SS), protein G 32 142 6.0E-41 T 13-09-2016 IPR013545 Type II secretion system protein G THL1_RS25010 3eff66aede5d8a8f7a7bcb0f3c32d887 144 PANTHER PTHR30093:SF9 1 143 1.3E-66 T 13-09-2016 THL1_RS25010 3eff66aede5d8a8f7a7bcb0f3c32d887 144 PANTHER PTHR30093 1 143 1.3E-66 T 13-09-2016 THL1_RS25010 3eff66aede5d8a8f7a7bcb0f3c32d887 144 PRINTS PR00813 Bacterial general secretion pathway protein G signature 9 34 1.5E-19 T 13-09-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THL1_RS25010 3eff66aede5d8a8f7a7bcb0f3c32d887 144 PRINTS PR00813 Bacterial general secretion pathway protein G signature 45 63 1.5E-19 T 13-09-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THL1_RS25010 3eff66aede5d8a8f7a7bcb0f3c32d887 144 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS23710 93ed9e913ae0eac5fe1820a3240656e7 278 PANTHER PTHR39456:SF2 1 278 9.1E-131 T 13-09-2016 THL1_RS23710 93ed9e913ae0eac5fe1820a3240656e7 278 PIRSF PIRSF007580 1 277 5.5E-93 T 13-09-2016 IPR016516 Uncharacterised conserved protein UCP07580 THL1_RS23710 93ed9e913ae0eac5fe1820a3240656e7 278 PANTHER PTHR39456 1 278 9.1E-131 T 13-09-2016 THL1_RS23710 93ed9e913ae0eac5fe1820a3240656e7 278 Pfam PF10118 Predicted metal-dependent hydrolase 13 258 2.7E-90 T 13-09-2016 IPR016516 Uncharacterised conserved protein UCP07580 THL1_RS08260 390b26a3e2cf5de47ca2fed66405abac 199 Gene3D G3DSA:3.40.50.720 1 198 5.9E-35 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS08260 390b26a3e2cf5de47ca2fed66405abac 199 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 170 5.8E-11 T 13-09-2016 THL1_RS08260 390b26a3e2cf5de47ca2fed66405abac 199 SUPERFAMILY SSF51735 1 198 4.03E-21 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS08260 390b26a3e2cf5de47ca2fed66405abac 199 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 144 1.3E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08260 390b26a3e2cf5de47ca2fed66405abac 199 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 1.3E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08260 390b26a3e2cf5de47ca2fed66405abac 199 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 162 1.3E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS08260 390b26a3e2cf5de47ca2fed66405abac 199 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 54 65 1.3E-7 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS13695 7c4fa526037f8ba22c32d55ef5643c27 268 PANTHER PTHR30502 5 265 1.4E-110 T 13-09-2016 THL1_RS13695 7c4fa526037f8ba22c32d55ef5643c27 268 PANTHER PTHR30502:SF5 5 265 1.4E-110 T 13-09-2016 THL1_RS13695 7c4fa526037f8ba22c32d55ef5643c27 268 Gene3D G3DSA:3.20.20.60 3 254 6.5E-80 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS13695 7c4fa526037f8ba22c32d55ef5643c27 268 TIGRFAM TIGR02311 HpaI: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 6 254 2.0E-128 T 13-09-2016 IPR012689 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase GO:0010124|GO:0018802 KEGG: 00350+4.1.2.52|UniPathway: UPA00208 THL1_RS13695 7c4fa526037f8ba22c32d55ef5643c27 268 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 243 8.8E-62 T 13-09-2016 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 THL1_RS13695 7c4fa526037f8ba22c32d55ef5643c27 268 SUPERFAMILY SSF51621 2 254 1.12E-84 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS21165 3c788b763995df9782e8bbb8cfbd5c1f 334 PANTHER PTHR10289 4 331 2.7E-149 T 13-09-2016 THL1_RS21165 3c788b763995df9782e8bbb8cfbd5c1f 334 SUPERFAMILY SSF53383 4 332 1.81E-111 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS21165 3c788b763995df9782e8bbb8cfbd5c1f 334 Gene3D G3DSA:3.90.1150.10 248 331 1.4E-22 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS21165 3c788b763995df9782e8bbb8cfbd5c1f 334 Pfam PF01212 Beta-eliminating lyase 5 283 6.1E-92 T 13-09-2016 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 THL1_RS21165 3c788b763995df9782e8bbb8cfbd5c1f 334 PIRSF PIRSF017617 1 334 1.7E-128 T 13-09-2016 IPR023603 Threonine aldolase THL1_RS21165 3c788b763995df9782e8bbb8cfbd5c1f 334 Gene3D G3DSA:3.40.640.10 2 247 6.8E-84 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS21165 3c788b763995df9782e8bbb8cfbd5c1f 334 PANTHER PTHR10289:SF5 4 331 2.7E-149 T 13-09-2016 THL1_RS26460 c2511ee75102a74650df94497b5dd077 235 PIRSF PIRSF015601 1 235 3.1E-48 T 13-09-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS26460 c2511ee75102a74650df94497b5dd077 235 Gene3D G3DSA:3.40.1280.10 2 234 2.8E-56 T 13-09-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THL1_RS26460 c2511ee75102a74650df94497b5dd077 235 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 15 232 2.3E-23 T 13-09-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS26460 c2511ee75102a74650df94497b5dd077 235 PANTHER PTHR30027 9 234 3.5E-43 T 13-09-2016 THL1_RS26460 c2511ee75102a74650df94497b5dd077 235 SUPERFAMILY SSF75217 72 234 1.57E-35 T 13-09-2016 IPR029028 Alpha/beta knot methyltransferases THL1_RS26460 c2511ee75102a74650df94497b5dd077 235 Pfam PF04452 RNA methyltransferase 17 234 2.3E-42 T 13-09-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS26460 c2511ee75102a74650df94497b5dd077 235 PANTHER PTHR30027:SF3 9 234 3.5E-43 T 13-09-2016 THL1_RS21520 b434b77afc3d83b71249417f0909310c 211 Pfam PF09347 Domain of unknown function (DUF1989) 18 184 2.0E-65 T 13-09-2016 IPR018959 Domain of unknown function DUF1989 THL1_RS21520 b434b77afc3d83b71249417f0909310c 211 TIGRFAM TIGR03424 urea_degr_1: urea carboxylase-associated protein 1 13 210 7.3E-100 T 13-09-2016 IPR017791 Urea carboxylase-associated protein 1 THL1_RS21520 b434b77afc3d83b71249417f0909310c 211 PANTHER PTHR31527 10 211 1.8E-56 T 13-09-2016 THL1_RS21520 b434b77afc3d83b71249417f0909310c 211 PANTHER PTHR31527:SF0 10 211 1.8E-56 T 13-09-2016 THL1_RS08595 8e5adda4b532aacd2ed5f1c6a405fea4 733 SMART SM00267 278 449 3.5E-68 T 13-09-2016 IPR000160 GGDEF domain THL1_RS08595 8e5adda4b532aacd2ed5f1c6a405fea4 733 Pfam PF03707 Bacterial signalling protein N terminal repeat 71 127 4.3E-17 T 13-09-2016 IPR005330 MHYT domain THL1_RS08595 8e5adda4b532aacd2ed5f1c6a405fea4 733 Pfam PF03707 Bacterial signalling protein N terminal repeat 201 234 3.7E-7 T 13-09-2016 IPR005330 MHYT domain THL1_RS08595 8e5adda4b532aacd2ed5f1c6a405fea4 733 Pfam PF03707 Bacterial signalling protein N terminal repeat 134 184 5.0E-13 T 13-09-2016 IPR005330 MHYT domain THL1_RS08595 8e5adda4b532aacd2ed5f1c6a405fea4 733 Gene3D G3DSA:3.20.20.450 462 713 3.7E-102 T 13-09-2016 IPR001633 EAL domain THL1_RS08595 8e5adda4b532aacd2ed5f1c6a405fea4 733 Gene3D G3DSA:3.30.70.270 291 457 6.3E-59 T 13-09-2016 THL1_RS08595 8e5adda4b532aacd2ed5f1c6a405fea4 733 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 285 447 3.1E-48 T 13-09-2016 IPR000160 GGDEF domain THL1_RS08595 8e5adda4b532aacd2ed5f1c6a405fea4 733 Pfam PF00563 EAL domain 465 701 6.8E-78 T 13-09-2016 IPR001633 EAL domain THL1_RS08595 8e5adda4b532aacd2ed5f1c6a405fea4 733 SUPERFAMILY SSF55073 294 450 5.49E-52 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS08595 8e5adda4b532aacd2ed5f1c6a405fea4 733 SUPERFAMILY SSF141868 466 713 2.48E-91 T 13-09-2016 IPR001633 EAL domain THL1_RS08595 8e5adda4b532aacd2ed5f1c6a405fea4 733 PANTHER PTHR33121:SF13 475 728 5.6E-85 T 13-09-2016 THL1_RS08595 8e5adda4b532aacd2ed5f1c6a405fea4 733 SMART SM00052 459 706 1.2E-118 T 13-09-2016 IPR001633 EAL domain THL1_RS08595 8e5adda4b532aacd2ed5f1c6a405fea4 733 Pfam PF00990 Diguanylate cyclase, GGDEF domain 289 445 1.1E-51 T 13-09-2016 IPR000160 GGDEF domain THL1_RS08595 8e5adda4b532aacd2ed5f1c6a405fea4 733 PANTHER PTHR33121 475 728 5.6E-85 T 13-09-2016 THL1_RS21675 abfbcff8214b38052e5b220f10a0ce81 323 PIRSF PIRSF036979 15 318 1.6E-74 T 13-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 THL1_RS21675 abfbcff8214b38052e5b220f10a0ce81 323 Pfam PF00491 Arginase family 35 310 1.0E-74 T 13-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 THL1_RS21675 abfbcff8214b38052e5b220f10a0ce81 323 TIGRFAM TIGR01230 agmatinase: agmatinase 29 311 6.9E-56 T 13-09-2016 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|UniPathway: UPA00534 THL1_RS21675 abfbcff8214b38052e5b220f10a0ce81 323 ProSitePatterns PS01053 Arginase family signature. 240 261 - T 13-09-2016 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 Reactome: REACT_13 THL1_RS21675 abfbcff8214b38052e5b220f10a0ce81 323 PANTHER PTHR11358 1 315 2.9E-70 T 13-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 THL1_RS21675 abfbcff8214b38052e5b220f10a0ce81 323 Gene3D G3DSA:3.40.800.10 8 318 1.3E-90 T 13-09-2016 IPR023696 Ureohydrolase domain THL1_RS21675 abfbcff8214b38052e5b220f10a0ce81 323 SUPERFAMILY SSF52768 5 318 1.42E-81 T 13-09-2016 THL1_RS17890 cceaaa75fb5670ee5b0980d569830bca 488 PANTHER PTHR23501 15 483 2.2E-105 T 13-09-2016 THL1_RS17890 cceaaa75fb5670ee5b0980d569830bca 488 PANTHER PTHR23501:SF65 15 483 2.2E-105 T 13-09-2016 THL1_RS17890 cceaaa75fb5670ee5b0980d569830bca 488 Gene3D G3DSA:1.20.1250.20 459 485 6.0E-21 T 13-09-2016 THL1_RS17890 cceaaa75fb5670ee5b0980d569830bca 488 Gene3D G3DSA:1.20.1250.20 17 195 3.0E-25 T 13-09-2016 THL1_RS17890 cceaaa75fb5670ee5b0980d569830bca 488 Gene3D G3DSA:1.20.1250.20 259 423 6.0E-21 T 13-09-2016 THL1_RS17890 cceaaa75fb5670ee5b0980d569830bca 488 SUPERFAMILY SSF103473 459 485 1.57E-59 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS17890 cceaaa75fb5670ee5b0980d569830bca 488 SUPERFAMILY SSF103473 251 423 1.57E-59 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS17890 cceaaa75fb5670ee5b0980d569830bca 488 SUPERFAMILY SSF103473 7 201 1.57E-59 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS17890 cceaaa75fb5670ee5b0980d569830bca 488 Pfam PF07690 Major Facilitator Superfamily 24 412 3.1E-50 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS03385 ff1c458d03b11e73cff2b44c7ead0013 478 PANTHER PTHR21666 203 473 4.4E-74 T 13-09-2016 THL1_RS03385 ff1c458d03b11e73cff2b44c7ead0013 478 SUPERFAMILY SSF51261 187 436 2.56E-73 T 13-09-2016 IPR011055 Duplicated hybrid motif THL1_RS03385 ff1c458d03b11e73cff2b44c7ead0013 478 PANTHER PTHR21666:SF221 203 473 4.4E-74 T 13-09-2016 THL1_RS03385 ff1c458d03b11e73cff2b44c7ead0013 478 Pfam PF04225 Opacity-associated protein A LysM-like domain 115 190 6.1E-7 T 13-09-2016 IPR007340 Opacity-associated protein A THL1_RS03385 ff1c458d03b11e73cff2b44c7ead0013 478 Pfam PF01551 Peptidase family M23 339 435 5.1E-32 T 13-09-2016 IPR016047 Peptidase M23 THL1_RS03385 ff1c458d03b11e73cff2b44c7ead0013 478 Gene3D G3DSA:2.70.70.10 294 437 5.5E-45 T 13-09-2016 THL1_RS02265 f69ee7a4a47b5173ebb222821667ee6f 429 Pfam PF01266 FAD dependent oxidoreductase 34 385 8.6E-50 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS02265 f69ee7a4a47b5173ebb222821667ee6f 429 PANTHER PTHR13847:SF196 1 429 1.8E-117 T 13-09-2016 THL1_RS02265 f69ee7a4a47b5173ebb222821667ee6f 429 SUPERFAMILY SSF51905 31 334 3.56E-42 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS02265 f69ee7a4a47b5173ebb222821667ee6f 429 Gene3D G3DSA:3.50.50.60 350 399 9.0E-43 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS02265 f69ee7a4a47b5173ebb222821667ee6f 429 Gene3D G3DSA:3.50.50.60 25 123 9.0E-43 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS02265 f69ee7a4a47b5173ebb222821667ee6f 429 Gene3D G3DSA:3.50.50.60 177 257 9.0E-43 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS02265 f69ee7a4a47b5173ebb222821667ee6f 429 PANTHER PTHR13847 1 429 1.8E-117 T 13-09-2016 THL1_RS25195 0d1f9252bfc72bd2b10ba6c1dcb06e10 199 Pfam PF13590 Domain of unknown function (DUF4136) 50 198 5.0E-20 T 13-09-2016 IPR025411 Domain of unknown function DUF4136 THL1_RS13620 e05118f50ee2b320faa34dc332cbeabe 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.7E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS13620 e05118f50ee2b320faa34dc332cbeabe 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.7E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS13620 e05118f50ee2b320faa34dc332cbeabe 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.7E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS13620 e05118f50ee2b320faa34dc332cbeabe 317 PANTHER PTHR30126:SF10 1 305 6.5E-181 T 13-09-2016 THL1_RS13620 e05118f50ee2b320faa34dc332cbeabe 317 Pfam PF03466 LysR substrate binding domain 87 288 4.0E-37 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS13620 e05118f50ee2b320faa34dc332cbeabe 317 PANTHER PTHR30126 1 305 6.5E-181 T 13-09-2016 THL1_RS13620 e05118f50ee2b320faa34dc332cbeabe 317 Gene3D G3DSA:1.10.10.10 1 82 2.2E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13620 e05118f50ee2b320faa34dc332cbeabe 317 SUPERFAMILY SSF53850 89 292 1.96E-35 T 13-09-2016 THL1_RS13620 e05118f50ee2b320faa34dc332cbeabe 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 8.6E-17 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS13620 e05118f50ee2b320faa34dc332cbeabe 317 Gene3D G3DSA:3.40.190.10 88 188 3.4E-19 T 13-09-2016 THL1_RS13620 e05118f50ee2b320faa34dc332cbeabe 317 Gene3D G3DSA:3.40.190.10 189 262 5.6E-11 T 13-09-2016 THL1_RS13620 e05118f50ee2b320faa34dc332cbeabe 317 SUPERFAMILY SSF46785 1 110 9.8E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS16940 0c0242629d206f705a802bfae5e6187d 302 Gene3D G3DSA:1.10.10.10 1 87 2.3E-28 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS16940 0c0242629d206f705a802bfae5e6187d 302 Gene3D G3DSA:3.40.190.10 89 180 3.0E-19 T 13-09-2016 THL1_RS16940 0c0242629d206f705a802bfae5e6187d 302 Pfam PF03466 LysR substrate binding domain 87 292 1.4E-31 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS16940 0c0242629d206f705a802bfae5e6187d 302 SUPERFAMILY SSF53850 88 296 9.23E-36 T 13-09-2016 THL1_RS16940 0c0242629d206f705a802bfae5e6187d 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.0E-21 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS16940 0c0242629d206f705a802bfae5e6187d 302 Gene3D G3DSA:3.40.190.10 181 245 5.0E-10 T 13-09-2016 THL1_RS16940 0c0242629d206f705a802bfae5e6187d 302 PANTHER PTHR30126 1 294 1.3E-62 T 13-09-2016 THL1_RS16940 0c0242629d206f705a802bfae5e6187d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.3E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS16940 0c0242629d206f705a802bfae5e6187d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.3E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS16940 0c0242629d206f705a802bfae5e6187d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.3E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS16940 0c0242629d206f705a802bfae5e6187d 302 SUPERFAMILY SSF46785 1 87 1.6E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20475 721c44186398d685aa8e88c9d4e58928 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 261 3.5E-51 T 13-09-2016 THL1_RS20475 721c44186398d685aa8e88c9d4e58928 264 SUPERFAMILY SSF51735 14 262 6.52E-70 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20475 721c44186398d685aa8e88c9d4e58928 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 7.6E-30 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20475 721c44186398d685aa8e88c9d4e58928 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 7.6E-30 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20475 721c44186398d685aa8e88c9d4e58928 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 7.6E-30 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20475 721c44186398d685aa8e88c9d4e58928 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 7.6E-30 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20475 721c44186398d685aa8e88c9d4e58928 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 7.6E-30 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20475 721c44186398d685aa8e88c9d4e58928 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 7.6E-30 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20475 721c44186398d685aa8e88c9d4e58928 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 3.3E-8 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20475 721c44186398d685aa8e88c9d4e58928 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 3.3E-8 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20475 721c44186398d685aa8e88c9d4e58928 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 3.3E-8 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20475 721c44186398d685aa8e88c9d4e58928 264 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 199 9.4E-4 T 13-09-2016 THL1_RS20475 721c44186398d685aa8e88c9d4e58928 264 Gene3D G3DSA:3.40.50.720 8 262 5.3E-75 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20475 721c44186398d685aa8e88c9d4e58928 264 PANTHER PTHR24322 19 150 2.1E-45 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS20475 721c44186398d685aa8e88c9d4e58928 264 PANTHER PTHR24322 168 200 2.1E-45 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS09300 5cebe5f216a3ba1c1cf3c73330d7d29a 506 PIRSF PIRSF002744 1 486 9.4E-97 T 13-09-2016 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 THL1_RS09300 5cebe5f216a3ba1c1cf3c73330d7d29a 506 PANTHER PTHR31806:SF2 1 487 3.9E-223 T 13-09-2016 THL1_RS09300 5cebe5f216a3ba1c1cf3c73330d7d29a 506 PANTHER PTHR31806 1 487 3.9E-223 T 13-09-2016 THL1_RS09300 5cebe5f216a3ba1c1cf3c73330d7d29a 506 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 20 446 9.4E-48 T 13-09-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 THL1_RS06165 d55b0cf1e27493ba544345badf026944 228 SUPERFAMILY SSF103088 74 191 1.1E-25 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS06165 d55b0cf1e27493ba544345badf026944 228 Pfam PF00691 OmpA family 91 173 1.0E-17 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS06165 d55b0cf1e27493ba544345badf026944 228 PANTHER PTHR30128 91 191 1.7E-23 T 13-09-2016 THL1_RS06165 d55b0cf1e27493ba544345badf026944 228 Gene3D G3DSA:3.30.1330.60 89 190 8.1E-26 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS06165 d55b0cf1e27493ba544345badf026944 228 PRINTS PR01021 OMPA domain signature 122 137 1.0E-13 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS06165 d55b0cf1e27493ba544345badf026944 228 PRINTS PR01021 OMPA domain signature 137 153 1.0E-13 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS06165 d55b0cf1e27493ba544345badf026944 228 PRINTS PR01021 OMPA domain signature 91 113 1.0E-13 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS06165 d55b0cf1e27493ba544345badf026944 228 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 137 154 1.6E-5 T 13-09-2016 THL1_RS06165 d55b0cf1e27493ba544345badf026944 228 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 108 134 1.6E-5 T 13-09-2016 THL1_RS06165 d55b0cf1e27493ba544345badf026944 228 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 155 174 1.6E-5 T 13-09-2016 THL1_RS22425 515d666ed8f7c9d076efd15a10bfd2ef 121 PANTHER PTHR34299 1 120 1.6E-36 T 13-09-2016 THL1_RS22425 515d666ed8f7c9d076efd15a10bfd2ef 121 PANTHER PTHR34299:SF1 1 120 1.6E-36 T 13-09-2016 THL1_RS22425 515d666ed8f7c9d076efd15a10bfd2ef 121 Gene3D G3DSA:1.10.3830.10 5 120 5.6E-42 T 13-09-2016 THL1_RS22425 515d666ed8f7c9d076efd15a10bfd2ef 121 Pfam PF01219 Prokaryotic diacylglycerol kinase 18 119 5.2E-32 T 13-09-2016 IPR000829 Diacylglycerol kinase, prokaryotic GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 THL1_RS01650 004489001b922cf5ed56dc33df7ad895 105 SUPERFAMILY SSF141488 23 103 7.45E-18 T 13-09-2016 IPR018660 C-type lysozyme, inhibitor THL1_RS01650 004489001b922cf5ed56dc33df7ad895 105 Pfam PF09864 Membrane-bound lysozyme-inhibitor of c-type lysozyme 29 96 9.8E-15 T 13-09-2016 IPR018660 C-type lysozyme, inhibitor THL1_RS17320 3a04e0ecc6b48c1c5e31ba91814ef775 392 TIGRFAM TIGR02783 TrbL_P: P-type conjugative transfer protein TrbL 2 297 8.6E-65 T 13-09-2016 IPR014150 Conjugal transfer, TrbL THL1_RS17320 3a04e0ecc6b48c1c5e31ba91814ef775 392 Pfam PF04610 TrbL/VirB6 plasmid conjugal transfer protein 38 251 4.1E-50 T 13-09-2016 IPR007688 Plasmid conjugal transfer TrbL/VirB6 GO:0030255 THL1_RS06215 e11822eb3c0578881c793a9b9a8574d0 105 Gene3D G3DSA:3.30.70.830 1 102 5.5E-44 T 13-09-2016 THL1_RS06215 e11822eb3c0578881c793a9b9a8574d0 105 PANTHER PTHR13799 2 104 1.2E-57 T 13-09-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 THL1_RS06215 e11822eb3c0578881c793a9b9a8574d0 105 PANTHER PTHR13799:SF18 2 104 1.2E-57 T 13-09-2016 THL1_RS06215 e11822eb3c0578881c793a9b9a8574d0 105 SUPERFAMILY SSF102705 2 101 3.14E-23 T 13-09-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 THL1_RS24765 01d81f0b34c4a08be66b31f613615eda 156 SUPERFAMILY SSF54523 7 109 7.85E-17 T 13-09-2016 THL1_RS24765 01d81f0b34c4a08be66b31f613615eda 156 Pfam PF13544 Type IV pilin N-term methylation site GFxxxE 1 26 6.1E-8 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS24765 01d81f0b34c4a08be66b31f613615eda 156 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 27 5.5E-7 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS24765 01d81f0b34c4a08be66b31f613615eda 156 PRINTS PR00813 Bacterial general secretion pathway protein G signature 6 31 1.9E-6 T 13-09-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THL1_RS24765 01d81f0b34c4a08be66b31f613615eda 156 PRINTS PR00813 Bacterial general secretion pathway protein G signature 42 60 1.9E-6 T 13-09-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THL1_RS24765 01d81f0b34c4a08be66b31f613615eda 156 Gene3D G3DSA:3.30.700.10 7 77 4.3E-9 T 13-09-2016 THL1_RS27895 2a529340e6f79559c5221d689795d428 126 PANTHER PTHR11803:SF13 1 126 2.8E-53 T 13-09-2016 THL1_RS27895 2a529340e6f79559c5221d689795d428 126 SUPERFAMILY SSF55298 1 125 2.51E-46 T 13-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THL1_RS27895 2a529340e6f79559c5221d689795d428 126 PANTHER PTHR11803 1 126 2.8E-53 T 13-09-2016 IPR006175 YjgF/YER057c/UK114 family THL1_RS27895 2a529340e6f79559c5221d689795d428 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 124 5.4E-54 T 13-09-2016 IPR006056 RidA family THL1_RS27895 2a529340e6f79559c5221d689795d428 126 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 101 119 - T 13-09-2016 IPR019897 RidA, conserved site THL1_RS27895 2a529340e6f79559c5221d689795d428 126 Pfam PF01042 Endoribonuclease L-PSP 10 124 7.0E-43 T 13-09-2016 IPR006175 YjgF/YER057c/UK114 family THL1_RS27895 2a529340e6f79559c5221d689795d428 126 Gene3D G3DSA:3.30.1330.40 3 122 2.7E-50 T 13-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THL1_RS27340 45ec35a6f1eb6e6f93fdbece1654d7cb 186 PANTHER PTHR30353 1 184 1.8E-85 T 13-09-2016 IPR032818 DedA family THL1_RS27340 45ec35a6f1eb6e6f93fdbece1654d7cb 186 Pfam PF09335 SNARE associated Golgi protein 22 139 4.0E-15 T 13-09-2016 IPR032816 SNARE associated Golgi protein THL1_RS27340 45ec35a6f1eb6e6f93fdbece1654d7cb 186 PANTHER PTHR30353:SF8 1 184 1.8E-85 T 13-09-2016 THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 Pfam PF02785 Biotin carboxylase C-terminal domain 336 443 8.0E-38 T 13-09-2016 IPR005482 Biotin carboxylase, C-terminal THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 601 618 - T 13-09-2016 IPR001882 Biotin-binding site THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 9.0E-81 T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 Gene3D G3DSA:2.40.50.100 577 645 1.9E-25 T 13-09-2016 THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 Pfam PF00364 Biotin-requiring enzyme 579 644 1.1E-17 T 13-09-2016 IPR000089 Biotin/lipoyl attachment THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 SUPERFAMILY SSF52440 1 113 6.19E-45 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 SUPERFAMILY SSF56059 83 348 7.25E-70 T 13-09-2016 THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 Gene3D G3DSA:3.30.1490.20 129 202 1.6E-31 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 Gene3D G3DSA:3.40.50.20 1 128 5.7E-49 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 Gene3D G3DSA:3.30.470.20 205 448 5.0E-104 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 5.3E-42 T 13-09-2016 IPR005481 Biotin carboxylase-like, N-terminal domain THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 SMART SM00878 336 443 4.4E-57 T 13-09-2016 IPR005482 Biotin carboxylase, C-terminal THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 SUPERFAMILY SSF51230 570 645 1.44E-21 T 13-09-2016 IPR011053 Single hybrid motif THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 SUPERFAMILY SSF51246 332 449 4.08E-40 T 13-09-2016 IPR011054 Rudiment single hybrid motif THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 PANTHER PTHR18866 1 645 0.0 T 13-09-2016 THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 PANTHER PTHR18866:SF102 1 645 0.0 T 13-09-2016 THL1_RS27595 7d0ffc89279828b8e6e2fac7cb0a6b78 648 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 13-09-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THL1_RS27630 b5de69f2a0532b7de9d7bb50ea1e540b 640 SMART SM00304 398 458 7.9 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS27630 b5de69f2a0532b7de9d7bb50ea1e540b 640 SMART SM00304 309 363 6.4E-15 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS27630 b5de69f2a0532b7de9d7bb50ea1e540b 640 SUPERFAMILY SSF103190 106 194 1.6E-12 T 13-09-2016 IPR029151 Periplasmic sensor domain-like THL1_RS27630 b5de69f2a0532b7de9d7bb50ea1e540b 640 Pfam PF02743 Cache domain 52 272 1.5E-35 T 13-09-2016 IPR033479 Double Cache domain 1 THL1_RS27630 b5de69f2a0532b7de9d7bb50ea1e540b 640 SUPERFAMILY SSF58104 331 640 4.97E-76 T 13-09-2016 THL1_RS27630 b5de69f2a0532b7de9d7bb50ea1e540b 640 Pfam PF00672 HAMP domain 290 359 1.3E-14 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS27630 b5de69f2a0532b7de9d7bb50ea1e540b 640 PANTHER PTHR32089:SF39 30 640 2.6E-292 T 13-09-2016 THL1_RS27630 b5de69f2a0532b7de9d7bb50ea1e540b 640 Gene3D G3DSA:1.10.287.950 392 608 6.8E-57 T 13-09-2016 THL1_RS27630 b5de69f2a0532b7de9d7bb50ea1e540b 640 SMART SM00283 378 639 3.4E-94 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS27630 b5de69f2a0532b7de9d7bb50ea1e540b 640 Gene3D G3DSA:3.30.450.20 152 286 8.9E-33 T 13-09-2016 THL1_RS27630 b5de69f2a0532b7de9d7bb50ea1e540b 640 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 437 638 2.4E-47 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS27630 b5de69f2a0532b7de9d7bb50ea1e540b 640 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 392 421 2.0E-9 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS27630 b5de69f2a0532b7de9d7bb50ea1e540b 640 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 505 534 2.0E-9 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS27630 b5de69f2a0532b7de9d7bb50ea1e540b 640 PANTHER PTHR32089 30 640 2.6E-292 T 13-09-2016 THL1_RS26170 3c5b86c0952cb745666733ccbaa91834 353 TIGRFAM TIGR02193 heptsyl_trn_I: lipopolysaccharide heptosyltransferase I 2 295 1.9E-113 T 13-09-2016 IPR011908 Lipopolysaccharide heptosyltransferase I GO:0008920|GO:0009244 KEGG: 00231+2.-.-.-|UniPathway: UPA00958 THL1_RS26170 3c5b86c0952cb745666733ccbaa91834 353 PANTHER PTHR30160 1 349 3.7E-173 T 13-09-2016 THL1_RS26170 3c5b86c0952cb745666733ccbaa91834 353 SUPERFAMILY SSF53756 2 347 1.13E-81 T 13-09-2016 THL1_RS26170 3c5b86c0952cb745666733ccbaa91834 353 Gene3D G3DSA:3.40.50.2000 2 154 7.1E-34 T 13-09-2016 THL1_RS26170 3c5b86c0952cb745666733ccbaa91834 353 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 75 313 4.7E-79 T 13-09-2016 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 THL1_RS26170 3c5b86c0952cb745666733ccbaa91834 353 Gene3D G3DSA:3.40.50.2000 168 347 1.4E-49 T 13-09-2016 THL1_RS26170 3c5b86c0952cb745666733ccbaa91834 353 PANTHER PTHR30160:SF8 1 349 3.7E-173 T 13-09-2016 THL1_RS13105 ee94cc5d8818a8b13f614580836ca930 285 PANTHER PTHR30151:SF7 36 285 3.3E-89 T 13-09-2016 THL1_RS13105 ee94cc5d8818a8b13f614580836ca930 285 SUPERFAMILY SSF161098 91 271 1.3E-24 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS13105 ee94cc5d8818a8b13f614580836ca930 285 Gene3D G3DSA:1.10.3720.10 86 282 2.1E-23 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS13105 ee94cc5d8818a8b13f614580836ca930 285 PANTHER PTHR30151 36 285 3.3E-89 T 13-09-2016 THL1_RS13105 ee94cc5d8818a8b13f614580836ca930 285 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 78 276 3.9E-72 T 13-09-2016 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 THL1_RS13105 ee94cc5d8818a8b13f614580836ca930 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 281 1.5E-20 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS19555 c174f083dd7a97cd3e612b3d80d004b9 153 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 70 145 3.7E-33 T 13-09-2016 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 THL1_RS19555 c174f083dd7a97cd3e612b3d80d004b9 153 PANTHER PTHR22617 42 152 5.2E-34 T 13-09-2016 THL1_RS19555 c174f083dd7a97cd3e612b3d80d004b9 153 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 74 143 1.8E-24 T 13-09-2016 IPR001543 Surface presentation of antigen (SpoA) THL1_RS19555 c174f083dd7a97cd3e612b3d80d004b9 153 SUPERFAMILY SSF101801 70 151 2.09E-25 T 13-09-2016 IPR001543 Surface presentation of antigen (SpoA) THL1_RS19555 c174f083dd7a97cd3e612b3d80d004b9 153 Gene3D G3DSA:2.30.330.10 69 153 1.7E-37 T 13-09-2016 THL1_RS19555 c174f083dd7a97cd3e612b3d80d004b9 153 PRINTS PR00956 Flagellar motor switch protein FliN signature 119 134 2.3E-28 T 13-09-2016 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 THL1_RS19555 c174f083dd7a97cd3e612b3d80d004b9 153 PRINTS PR00956 Flagellar motor switch protein FliN signature 106 119 2.3E-28 T 13-09-2016 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 THL1_RS19555 c174f083dd7a97cd3e612b3d80d004b9 153 PRINTS PR00956 Flagellar motor switch protein FliN signature 90 106 2.3E-28 T 13-09-2016 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 THL1_RS19555 c174f083dd7a97cd3e612b3d80d004b9 153 PRINTS PR00956 Flagellar motor switch protein FliN signature 73 89 2.3E-28 T 13-09-2016 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 THL1_RS28590 2b2b25c76f9b1bd59468018160beb9de 113 SMART SM00563 1 113 2.6E-31 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS28590 2b2b25c76f9b1bd59468018160beb9de 113 PANTHER PTHR10434 1 113 1.0E-34 T 13-09-2016 THL1_RS28590 2b2b25c76f9b1bd59468018160beb9de 113 SUPERFAMILY SSF69593 1 112 7.59E-26 T 13-09-2016 THL1_RS28590 2b2b25c76f9b1bd59468018160beb9de 113 Pfam PF01553 Acyltransferase 2 112 1.5E-20 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS28590 2b2b25c76f9b1bd59468018160beb9de 113 Gene3D G3DSA:3.40.1130.10 1 113 5.6E-16 T 13-09-2016 THL1_RS22630 db625a471ff4593e0510596fe133bf7f 247 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 12 243 2.6E-99 T 13-09-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 THL1_RS22630 db625a471ff4593e0510596fe133bf7f 247 PANTHER PTHR21499 1 244 2.0E-115 T 13-09-2016 THL1_RS22630 db625a471ff4593e0510596fe133bf7f 247 PIRSF PIRSF005650 8 247 2.1E-90 T 13-09-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 THL1_RS22630 db625a471ff4593e0510596fe133bf7f 247 PANTHER PTHR21499:SF23 1 244 2.0E-115 T 13-09-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 THL1_RS22630 db625a471ff4593e0510596fe133bf7f 247 Hamap MF_01220_B Uridylate kinase [pyrH]. 10 243 44.036 T 13-09-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 THL1_RS22630 db625a471ff4593e0510596fe133bf7f 247 SUPERFAMILY SSF53633 10 242 3.27E-73 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS22630 db625a471ff4593e0510596fe133bf7f 247 Pfam PF00696 Amino acid kinase family 13 222 4.0E-28 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS22630 db625a471ff4593e0510596fe133bf7f 247 Gene3D G3DSA:3.40.1160.10 7 243 3.3E-86 T 13-09-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 THL1_RS11485 2d8c7115a57498fec7b7cb632c9d77e3 376 TIGRFAM TIGR03837 efp_adjacent_2: conserved hypothetical protein, PP_1857 family 4 372 2.8E-162 T 13-09-2016 IPR016633 Uncharacterised conserved protein UCP015557 THL1_RS11485 2d8c7115a57498fec7b7cb632c9d77e3 376 Pfam PF10093 Uncharacterized protein conserved in bacteria (DUF2331) 4 372 1.7E-156 T 13-09-2016 IPR016633 Uncharacterised conserved protein UCP015557 THL1_RS11485 2d8c7115a57498fec7b7cb632c9d77e3 376 PIRSF PIRSF015557 1 376 2.9E-165 T 13-09-2016 IPR016633 Uncharacterised conserved protein UCP015557 THL1_RS15725 e574319be4342c7307b8cd5c4cd1c7e5 347 SUPERFAMILY SSF49401 205 346 6.46E-13 T 13-09-2016 IPR008966 Adhesion domain THL1_RS15725 e574319be4342c7307b8cd5c4cd1c7e5 347 Gene3D G3DSA:2.60.40.1090 196 346 5.7E-9 T 13-09-2016 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 THL1_RS15725 e574319be4342c7307b8cd5c4cd1c7e5 347 Pfam PF00419 Fimbrial protein 197 346 5.6E-16 T 13-09-2016 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 THL1_RS14750 1867cb5fc500aab08f67e913c4cd5dfe 259 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 253 3.3E-61 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS14750 1867cb5fc500aab08f67e913c4cd5dfe 259 PANTHER PTHR18966:SF152 2 253 2.6E-61 T 13-09-2016 THL1_RS14750 1867cb5fc500aab08f67e913c4cd5dfe 259 Gene3D G3DSA:3.40.190.10 116 202 2.6E-23 T 13-09-2016 THL1_RS14750 1867cb5fc500aab08f67e913c4cd5dfe 259 PANTHER PTHR18966 2 253 2.6E-61 T 13-09-2016 THL1_RS14750 1867cb5fc500aab08f67e913c4cd5dfe 259 Gene3D G3DSA:3.40.190.10 213 253 4.3E-42 T 13-09-2016 THL1_RS14750 1867cb5fc500aab08f67e913c4cd5dfe 259 Gene3D G3DSA:3.40.190.10 24 113 4.3E-42 T 13-09-2016 THL1_RS14750 1867cb5fc500aab08f67e913c4cd5dfe 259 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 50 63 - T 13-09-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 THL1_RS14750 1867cb5fc500aab08f67e913c4cd5dfe 259 SUPERFAMILY SSF53850 4 252 1.99E-64 T 13-09-2016 THL1_RS14750 1867cb5fc500aab08f67e913c4cd5dfe 259 SMART SM00062 27 254 4.2E-61 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS28310 f5021ba2999d16eaebe3faadef437cab 160 SUPERFAMILY SSF54637 6 155 1.75E-46 T 13-09-2016 IPR029069 HotDog domain THL1_RS28310 f5021ba2999d16eaebe3faadef437cab 160 Pfam PF03061 Thioesterase superfamily 23 96 1.2E-18 T 13-09-2016 IPR006683 Thioesterase domain THL1_RS28310 f5021ba2999d16eaebe3faadef437cab 160 PANTHER PTHR11049 7 158 1.2E-72 T 13-09-2016 THL1_RS28310 f5021ba2999d16eaebe3faadef437cab 160 Gene3D G3DSA:3.10.129.10 7 155 1.8E-57 T 13-09-2016 IPR029069 HotDog domain THL1_RS02235 0a64027fee3b2e811102d1d3f0eae322 370 Gene3D G3DSA:3.60.21.30 69 273 2.0E-10 T 13-09-2016 THL1_RS02235 0a64027fee3b2e811102d1d3f0eae322 370 PANTHER PTHR33393:SF2 7 327 2.2E-61 T 13-09-2016 THL1_RS02235 0a64027fee3b2e811102d1d3f0eae322 370 SMART SM00854 9 290 7.0E-93 T 13-09-2016 IPR019079 Capsule synthesis protein, CapA THL1_RS02235 0a64027fee3b2e811102d1d3f0eae322 370 SUPERFAMILY SSF56300 60 298 4.1E-28 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS02235 0a64027fee3b2e811102d1d3f0eae322 370 SUPERFAMILY SSF56300 9 19 4.1E-28 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS02235 0a64027fee3b2e811102d1d3f0eae322 370 PANTHER PTHR33393 7 327 2.2E-61 T 13-09-2016 THL1_RS02235 0a64027fee3b2e811102d1d3f0eae322 370 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 9 290 7.4E-68 T 13-09-2016 IPR019079 Capsule synthesis protein, CapA THL1_RS00100 6e70f9d5ba79440892b880a5addc396a 315 Gene3D G3DSA:3.40.50.170 5 208 4.8E-76 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS00100 6e70f9d5ba79440892b880a5addc396a 315 Pfam PF00551 Formyl transferase 7 184 4.3E-47 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS00100 6e70f9d5ba79440892b880a5addc396a 315 Pfam PF02911 Formyl transferase, C-terminal domain 207 303 7.0E-27 T 13-09-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS00100 6e70f9d5ba79440892b880a5addc396a 315 SUPERFAMILY SSF50486 208 309 3.53E-31 T 13-09-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 THL1_RS00100 6e70f9d5ba79440892b880a5addc396a 315 PANTHER PTHR11138 1 306 6.8E-122 T 13-09-2016 THL1_RS00100 6e70f9d5ba79440892b880a5addc396a 315 SUPERFAMILY SSF53328 5 210 1.7E-67 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS00100 6e70f9d5ba79440892b880a5addc396a 315 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 136 159 - T 13-09-2016 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS00100 6e70f9d5ba79440892b880a5addc396a 315 Gene3D G3DSA:3.10.25.10 210 306 2.5E-31 T 13-09-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS00100 6e70f9d5ba79440892b880a5addc396a 315 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 6 308 6.9E-94 T 13-09-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS00100 6e70f9d5ba79440892b880a5addc396a 315 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 5 306 37.215 T 13-09-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS18335 af0acb8ca708d3932d69e66e8e71810e 334 Gene3D G3DSA:3.90.180.10 3 140 1.6E-51 T 13-09-2016 IPR011032 GroES-like THL1_RS18335 af0acb8ca708d3932d69e66e8e71810e 334 PANTHER PTHR11695 23 334 1.1E-126 T 13-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 THL1_RS18335 af0acb8ca708d3932d69e66e8e71810e 334 Pfam PF00107 Zinc-binding dehydrogenase 158 281 1.3E-21 T 13-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THL1_RS18335 af0acb8ca708d3932d69e66e8e71810e 334 Gene3D G3DSA:3.40.50.720 141 301 4.9E-70 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18335 af0acb8ca708d3932d69e66e8e71810e 334 SUPERFAMILY SSF50129 4 143 5.14E-37 T 13-09-2016 IPR011032 GroES-like THL1_RS18335 af0acb8ca708d3932d69e66e8e71810e 334 SMART SM00829 18 331 1.1E-6 T 13-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THL1_RS18335 af0acb8ca708d3932d69e66e8e71810e 334 SUPERFAMILY SSF51735 124 296 4.04E-50 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18335 af0acb8ca708d3932d69e66e8e71810e 334 PANTHER PTHR11695:SF595 23 334 1.1E-126 T 13-09-2016 THL1_RS18335 af0acb8ca708d3932d69e66e8e71810e 334 Pfam PF16884 N-terminal domain of oxidoreductase 6 112 3.4E-38 T 13-09-2016 THL1_RS09980 e61e2d84cc68ff03ed71a6317d1d769e 216 Gene3D G3DSA:3.20.20.70 11 210 1.2E-71 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS09980 e61e2d84cc68ff03ed71a6317d1d769e 216 PANTHER PTHR30246:SF0 9 215 1.3E-108 T 13-09-2016 THL1_RS09980 e61e2d84cc68ff03ed71a6317d1d769e 216 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 38 47 - T 13-09-2016 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562|UniPathway: UPA00227|UniPathway: UPA00856 THL1_RS09980 e61e2d84cc68ff03ed71a6317d1d769e 216 PANTHER PTHR30246 9 215 1.3E-108 T 13-09-2016 THL1_RS09980 e61e2d84cc68ff03ed71a6317d1d769e 216 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 9 207 1.4E-80 T 13-09-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 THL1_RS09980 e61e2d84cc68ff03ed71a6317d1d769e 216 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 126 139 - T 13-09-2016 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 THL1_RS09980 e61e2d84cc68ff03ed71a6317d1d769e 216 SUPERFAMILY SSF51569 11 208 2.75E-64 T 13-09-2016 THL1_RS09980 e61e2d84cc68ff03ed71a6317d1d769e 216 Pfam PF01081 KDPG and KHG aldolase 11 201 1.4E-69 T 13-09-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 THL1_RS08925 1f65696eabc3cf2cff693b4fddad4b16 459 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 357 458 1.6E-11 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS08925 1f65696eabc3cf2cff693b4fddad4b16 459 PANTHER PTHR24423 32 57 1.6E-98 T 13-09-2016 THL1_RS08925 1f65696eabc3cf2cff693b4fddad4b16 459 PANTHER PTHR24423 73 96 1.6E-98 T 13-09-2016 THL1_RS08925 1f65696eabc3cf2cff693b4fddad4b16 459 SUPERFAMILY SSF55874 320 458 4.06E-28 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS08925 1f65696eabc3cf2cff693b4fddad4b16 459 Gene3D G3DSA:1.10.287.130 244 300 1.1E-6 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS08925 1f65696eabc3cf2cff693b4fddad4b16 459 Gene3D G3DSA:3.30.565.10 320 458 4.1E-28 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS08925 1f65696eabc3cf2cff693b4fddad4b16 459 SMART SM00388 249 311 1.7E-4 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS08925 1f65696eabc3cf2cff693b4fddad4b16 459 PANTHER PTHR24423 191 457 1.6E-98 T 13-09-2016 THL1_RS08925 1f65696eabc3cf2cff693b4fddad4b16 459 SUPERFAMILY SSF47384 232 304 3.92E-7 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS08925 1f65696eabc3cf2cff693b4fddad4b16 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 6.7E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS08925 1f65696eabc3cf2cff693b4fddad4b16 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 403 6.7E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS08925 1f65696eabc3cf2cff693b4fddad4b16 459 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 6.7E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS08925 1f65696eabc3cf2cff693b4fddad4b16 459 PANTHER PTHR24423:SF496 32 57 1.6E-98 T 13-09-2016 THL1_RS08925 1f65696eabc3cf2cff693b4fddad4b16 459 PANTHER PTHR24423:SF496 73 96 1.6E-98 T 13-09-2016 THL1_RS08925 1f65696eabc3cf2cff693b4fddad4b16 459 SMART SM00387 354 459 7.2E-20 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS08925 1f65696eabc3cf2cff693b4fddad4b16 459 Pfam PF00512 His Kinase A (phospho-acceptor) domain 254 306 7.6E-7 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS08925 1f65696eabc3cf2cff693b4fddad4b16 459 PANTHER PTHR24423:SF496 191 457 1.6E-98 T 13-09-2016 THL1_RS11320 6a240c90c86faee9827b36bc170b6eda 469 PANTHER PTHR34595:SF3 3 469 5.4E-301 T 13-09-2016 THL1_RS11320 6a240c90c86faee9827b36bc170b6eda 469 PANTHER PTHR34595 3 469 5.4E-301 T 13-09-2016 THL1_RS11320 6a240c90c86faee9827b36bc170b6eda 469 PIRSF PIRSF005522 1 469 6.5E-232 T 13-09-2016 IPR016450 Uncharacterised conserved protein UCP005522 THL1_RS11320 6a240c90c86faee9827b36bc170b6eda 469 Pfam PF14403 Circularly permuted ATP-grasp type 2 72 445 1.1E-161 T 13-09-2016 IPR025841 Circularly permuted ATP-grasp type 2 THL1_RS11320 6a240c90c86faee9827b36bc170b6eda 469 SUPERFAMILY SSF56059 315 460 8.22E-67 T 13-09-2016 THL1_RS11320 6a240c90c86faee9827b36bc170b6eda 469 SUPERFAMILY SSF56059 15 210 8.22E-67 T 13-09-2016 THL1_RS01475 801c46ed82452482cc1bd1c86c7fc45f 162 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 4 159 37.33 T 13-09-2016 IPR022927 RNA pyrophosphohydrolase RppH THL1_RS01475 801c46ed82452482cc1bd1c86c7fc45f 162 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 13-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THL1_RS01475 801c46ed82452482cc1bd1c86c7fc45f 162 PRINTS PR00502 NUDIX hydrolase family signature 36 50 1.5E-6 T 13-09-2016 IPR020476 NUDIX hydrolase THL1_RS01475 801c46ed82452482cc1bd1c86c7fc45f 162 PRINTS PR00502 NUDIX hydrolase family signature 50 65 1.5E-6 T 13-09-2016 IPR020476 NUDIX hydrolase THL1_RS01475 801c46ed82452482cc1bd1c86c7fc45f 162 SUPERFAMILY SSF55811 10 160 1.62E-29 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS01475 801c46ed82452482cc1bd1c86c7fc45f 162 Pfam PF00293 NUDIX domain 10 149 1.0E-25 T 13-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 THL1_RS01475 801c46ed82452482cc1bd1c86c7fc45f 162 PANTHER PTHR23114 3 155 4.8E-51 T 13-09-2016 THL1_RS01475 801c46ed82452482cc1bd1c86c7fc45f 162 Gene3D G3DSA:3.90.79.10 6 154 9.1E-30 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS17180 a1b7c4460213f88cbeb1b79f9aa13063 412 SUPERFAMILY SSF53901 4 253 2.96E-45 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17180 a1b7c4460213f88cbeb1b79f9aa13063 412 Gene3D G3DSA:3.40.47.10 268 388 9.1E-18 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17180 a1b7c4460213f88cbeb1b79f9aa13063 412 Gene3D G3DSA:3.40.47.10 176 206 9.1E-18 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17180 a1b7c4460213f88cbeb1b79f9aa13063 412 PANTHER PTHR18919 132 410 1.5E-92 T 13-09-2016 THL1_RS17180 a1b7c4460213f88cbeb1b79f9aa13063 412 PANTHER PTHR18919 1 116 1.5E-92 T 13-09-2016 THL1_RS17180 a1b7c4460213f88cbeb1b79f9aa13063 412 PANTHER PTHR18919:SF8 132 410 1.5E-92 T 13-09-2016 THL1_RS17180 a1b7c4460213f88cbeb1b79f9aa13063 412 PANTHER PTHR18919:SF8 1 116 1.5E-92 T 13-09-2016 THL1_RS17180 a1b7c4460213f88cbeb1b79f9aa13063 412 SUPERFAMILY SSF53901 283 398 2.64E-24 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17180 a1b7c4460213f88cbeb1b79f9aa13063 412 Pfam PF02803 Thiolase, C-terminal domain 285 380 8.9E-7 T 13-09-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 THL1_RS17180 a1b7c4460213f88cbeb1b79f9aa13063 412 Gene3D G3DSA:3.40.47.10 9 117 8.0E-27 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17180 a1b7c4460213f88cbeb1b79f9aa13063 412 Gene3D G3DSA:3.40.47.10 221 246 8.0E-27 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17180 a1b7c4460213f88cbeb1b79f9aa13063 412 Pfam PF00108 Thiolase, N-terminal domain 4 212 7.5E-20 T 13-09-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 THL1_RS17180 a1b7c4460213f88cbeb1b79f9aa13063 412 PIRSF PIRSF000429 1 403 1.3E-53 T 13-09-2016 IPR002155 Thiolase GO:0008152|GO:0016747 THL1_RS20325 56a0d1c0937715f38a63be6fd1cc00ff 106 SUPERFAMILY SSF52821 3 103 1.09E-20 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS20325 56a0d1c0937715f38a63be6fd1cc00ff 106 Gene3D G3DSA:3.40.250.10 2 103 8.0E-15 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS20325 56a0d1c0937715f38a63be6fd1cc00ff 106 SMART SM00450 5 102 1.1E-8 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS20325 56a0d1c0937715f38a63be6fd1cc00ff 106 Pfam PF00581 Rhodanese-like domain 18 98 1.3E-5 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS27070 a91e50259e981dcd8f3c59323b5a8a3a 145 PANTHER PTHR31793 4 144 1.9E-68 T 13-09-2016 THL1_RS27070 a91e50259e981dcd8f3c59323b5a8a3a 145 Gene3D G3DSA:3.10.129.10 5 144 1.6E-53 T 13-09-2016 IPR029069 HotDog domain THL1_RS27070 a91e50259e981dcd8f3c59323b5a8a3a 145 SUPERFAMILY SSF54637 8 142 5.12E-41 T 13-09-2016 IPR029069 HotDog domain THL1_RS27070 a91e50259e981dcd8f3c59323b5a8a3a 145 Pfam PF13279 Thioesterase-like superfamily 20 137 5.2E-16 T 13-09-2016 THL1_RS27070 a91e50259e981dcd8f3c59323b5a8a3a 145 PANTHER PTHR31793:SF7 4 144 1.9E-68 T 13-09-2016 THL1_RS16285 29eadcadc2af2bcb80059fed2b6498d1 79 Gene3D G3DSA:1.10.260.40 15 64 4.5E-5 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS16285 29eadcadc2af2bcb80059fed2b6498d1 79 SUPERFAMILY SSF47413 15 66 6.33E-5 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS16285 29eadcadc2af2bcb80059fed2b6498d1 79 TIGRFAM TIGR04111 BcepMu_gp16: phage-associated protein, BcepMu gp16 family 11 64 3.4E-23 T 13-09-2016 IPR026365 Phage-associated protein, BcepMu gp16 family THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 SMART SM00387 330 439 2.5E-29 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 PANTHER PTHR24423 35 87 2.4E-61 T 13-09-2016 THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 Pfam PF00512 His Kinase A (phospho-acceptor) domain 225 288 5.1E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 Gene3D G3DSA:1.10.287.130 217 285 8.6E-14 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 SUPERFAMILY SSF158472 170 223 6.41E-7 T 13-09-2016 THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 SMART SM00304 169 224 1.2E-6 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 334 438 2.9E-19 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 PANTHER PTHR24423 163 437 2.4E-61 T 13-09-2016 THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 SMART SM00388 225 289 5.2E-12 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 PANTHER PTHR24423:SF477 163 437 2.4E-61 T 13-09-2016 THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 Pfam PF00672 HAMP domain 152 220 1.8E-12 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 381 3.9E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 417 3.9E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 436 3.9E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 395 3.9E-12 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 SUPERFAMILY SSF55874 279 437 4.19E-36 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 Gene3D G3DSA:3.30.565.10 293 439 3.6E-37 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 PANTHER PTHR24423:SF477 35 87 2.4E-61 T 13-09-2016 THL1_RS19290 ebdbc916b0c1bdc9cfa759360fe87435 441 SUPERFAMILY SSF47384 208 288 3.92E-13 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS11570 e3f73075297cd500f6c039289f242fa8 233 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 1 217 1.5E-77 T 13-09-2016 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67 THL1_RS11570 e3f73075297cd500f6c039289f242fa8 233 TIGRFAM TIGR03840 TMPT_Se_Te: thiopurine S-methyltransferase, Se/Te detoxification family 4 216 3.7E-84 T 13-09-2016 IPR022474 Thiopurine S-methyltransferase, Se/Te detoxification GO:0008119|GO:0010038|GO:0032259 KEGG: 00983+2.1.1.67 THL1_RS11570 e3f73075297cd500f6c039289f242fa8 233 Hamap MF_00812 Thiopurine S-methyltransferase [tpm]. 1 217 38.914 T 13-09-2016 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67 THL1_RS11570 e3f73075297cd500f6c039289f242fa8 233 PIRSF PIRSF023956 1 219 1.9E-74 T 13-09-2016 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67 THL1_RS11570 e3f73075297cd500f6c039289f242fa8 233 PANTHER PTHR10259:SF16 1 224 1.1E-95 T 13-09-2016 THL1_RS11570 e3f73075297cd500f6c039289f242fa8 233 SUPERFAMILY SSF53335 1 214 2.52E-51 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS11570 e3f73075297cd500f6c039289f242fa8 233 PANTHER PTHR10259 1 224 1.1E-95 T 13-09-2016 THL1_RS11570 e3f73075297cd500f6c039289f242fa8 233 Gene3D G3DSA:3.40.50.150 16 217 1.8E-61 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS13355 4975e0064ba7f227e9ecdd99b7706617 137 SUPERFAMILY SSF51182 15 123 2.23E-16 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS13355 4975e0064ba7f227e9ecdd99b7706617 137 Pfam PF07883 Cupin domain 49 118 1.0E-12 T 13-09-2016 IPR013096 Cupin 2, conserved barrel THL1_RS13355 4975e0064ba7f227e9ecdd99b7706617 137 Gene3D G3DSA:2.60.120.10 39 123 1.0E-17 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS13355 4975e0064ba7f227e9ecdd99b7706617 137 PANTHER PTHR38599:SF1 1 134 2.1E-34 T 13-09-2016 THL1_RS13355 4975e0064ba7f227e9ecdd99b7706617 137 PANTHER PTHR38599 1 134 2.1E-34 T 13-09-2016 THL1_RS04720 d0e564a4b42911bb89da69db990fb738 454 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 449 4.1E-199 T 13-09-2016 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 THL1_RS04720 d0e564a4b42911bb89da69db990fb738 454 SUPERFAMILY SSF54211 301 453 1.52E-41 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS04720 d0e564a4b42911bb89da69db990fb738 454 SUPERFAMILY SSF54211 253 267 1.52E-41 T 13-09-2016 IPR020568 Ribosomal protein S5 domain 2-type fold THL1_RS04720 d0e564a4b42911bb89da69db990fb738 454 PRINTS PR01874 DNA repair protein radA signature 10 34 2.8E-94 T 13-09-2016 THL1_RS04720 d0e564a4b42911bb89da69db990fb738 454 PRINTS PR01874 DNA repair protein radA signature 320 343 2.8E-94 T 13-09-2016 THL1_RS04720 d0e564a4b42911bb89da69db990fb738 454 PRINTS PR01874 DNA repair protein radA signature 122 139 2.8E-94 T 13-09-2016 THL1_RS04720 d0e564a4b42911bb89da69db990fb738 454 PRINTS PR01874 DNA repair protein radA signature 246 272 2.8E-94 T 13-09-2016 THL1_RS04720 d0e564a4b42911bb89da69db990fb738 454 PRINTS PR01874 DNA repair protein radA signature 172 196 2.8E-94 T 13-09-2016 THL1_RS04720 d0e564a4b42911bb89da69db990fb738 454 PRINTS PR01874 DNA repair protein radA signature 81 109 2.8E-94 T 13-09-2016 THL1_RS04720 d0e564a4b42911bb89da69db990fb738 454 PRINTS PR01874 DNA repair protein radA signature 211 239 2.8E-94 T 13-09-2016 THL1_RS04720 d0e564a4b42911bb89da69db990fb738 454 Pfam PF13541 Subunit ChlI of Mg-chelatase 366 428 3.1E-8 T 13-09-2016 THL1_RS04720 d0e564a4b42911bb89da69db990fb738 454 Gene3D G3DSA:3.40.50.300 56 275 8.9E-55 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04720 d0e564a4b42911bb89da69db990fb738 454 SMART SM00382 89 242 2.3E-9 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS04720 d0e564a4b42911bb89da69db990fb738 454 SUPERFAMILY SSF52540 67 288 2.15E-50 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04720 d0e564a4b42911bb89da69db990fb738 454 Pfam PF13481 AAA domain 67 220 1.4E-13 T 13-09-2016 THL1_RS04720 d0e564a4b42911bb89da69db990fb738 454 PANTHER PTHR32472 1 454 8.4E-217 T 13-09-2016 THL1_RS04720 d0e564a4b42911bb89da69db990fb738 454 Gene3D G3DSA:3.30.230.10 282 454 1.0E-36 T 13-09-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THL1_RS00435 d8382ef427e4b003e7b4fdbe4a98ccf3 347 PIRSF PIRSF029727 6 346 2.9E-149 T 13-09-2016 IPR016937 Uncharacterised conserved protein UCP029727 THL1_RS00435 d8382ef427e4b003e7b4fdbe4a98ccf3 347 Pfam PF11141 Protein of unknown function (DUF2914) 273 337 3.5E-25 T 13-09-2016 IPR022606 Protein of unknown function DUF2914 THL1_RS04865 15e40a1d120c9060acbffdce8f97aba7 167 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 5 162 17.398 T 13-09-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 THL1_RS04865 15e40a1d120c9060acbffdce8f97aba7 167 PANTHER PTHR33695:SF1 4 161 1.3E-60 T 13-09-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 THL1_RS04865 15e40a1d120c9060acbffdce8f97aba7 167 Pfam PF01252 Signal peptidase (SPase) II 14 156 2.8E-39 T 13-09-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 THL1_RS04865 15e40a1d120c9060acbffdce8f97aba7 167 TIGRFAM TIGR00077 lspA: signal peptidase II 8 161 8.5E-43 T 13-09-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 THL1_RS04865 15e40a1d120c9060acbffdce8f97aba7 167 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 100 115 6.3E-19 T 13-09-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 THL1_RS04865 15e40a1d120c9060acbffdce8f97aba7 167 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 137 153 6.3E-19 T 13-09-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 THL1_RS04865 15e40a1d120c9060acbffdce8f97aba7 167 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 52 60 6.3E-19 T 13-09-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 THL1_RS04865 15e40a1d120c9060acbffdce8f97aba7 167 ProSitePatterns PS00855 Signal peptidases II signature. 103 115 - T 13-09-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 THL1_RS04865 15e40a1d120c9060acbffdce8f97aba7 167 PANTHER PTHR33695 4 161 1.3E-60 T 13-09-2016 THL1_RS16930 0d9f46bd4021eb27b0501ea75a0b25e5 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 7.1E-35 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16930 0d9f46bd4021eb27b0501ea75a0b25e5 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 7.1E-35 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16930 0d9f46bd4021eb27b0501ea75a0b25e5 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 7.1E-35 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16930 0d9f46bd4021eb27b0501ea75a0b25e5 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 7.1E-35 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16930 0d9f46bd4021eb27b0501ea75a0b25e5 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 7.1E-35 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16930 0d9f46bd4021eb27b0501ea75a0b25e5 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 7.1E-35 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16930 0d9f46bd4021eb27b0501ea75a0b25e5 250 PANTHER PTHR24322 15 142 8.6E-53 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16930 0d9f46bd4021eb27b0501ea75a0b25e5 250 PANTHER PTHR24322 159 191 8.6E-53 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16930 0d9f46bd4021eb27b0501ea75a0b25e5 250 SUPERFAMILY SSF51735 10 250 1.56E-76 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS16930 0d9f46bd4021eb27b0501ea75a0b25e5 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 249 7.9E-58 T 13-09-2016 THL1_RS16930 0d9f46bd4021eb27b0501ea75a0b25e5 250 PANTHER PTHR24322:SF343 15 142 8.6E-53 T 13-09-2016 THL1_RS16930 0d9f46bd4021eb27b0501ea75a0b25e5 250 PANTHER PTHR24322:SF343 159 191 8.6E-53 T 13-09-2016 THL1_RS16930 0d9f46bd4021eb27b0501ea75a0b25e5 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 3.3E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16930 0d9f46bd4021eb27b0501ea75a0b25e5 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 3.3E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16930 0d9f46bd4021eb27b0501ea75a0b25e5 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 3.3E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16930 0d9f46bd4021eb27b0501ea75a0b25e5 250 Gene3D G3DSA:3.40.50.720 4 248 8.2E-77 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS22045 6d93613006a9726a57ac294974f88788 157 SUPERFAMILY SSF52833 4 154 2.13E-45 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS22045 6d93613006a9726a57ac294974f88788 157 PIRSF PIRSF000239 1 156 5.6E-25 T 13-09-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 THL1_RS22045 6d93613006a9726a57ac294974f88788 157 PANTHER PTHR10681 1 154 9.8E-41 T 13-09-2016 THL1_RS22045 6d93613006a9726a57ac294974f88788 157 Pfam PF00578 AhpC/TSA family 6 133 4.3E-32 T 13-09-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS22045 6d93613006a9726a57ac294974f88788 157 Gene3D G3DSA:3.40.30.10 2 154 4.0E-44 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS20985 392bb7e5230e1f3ab770d035c34928ec 527 PANTHER PTHR10668 2 525 2.2E-70 T 13-09-2016 THL1_RS20985 392bb7e5230e1f3ab770d035c34928ec 527 PANTHER PTHR10668:SF83 2 525 2.2E-70 T 13-09-2016 THL1_RS20985 392bb7e5230e1f3ab770d035c34928ec 527 Gene3D G3DSA:3.50.50.60 2 66 4.8E-30 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20985 392bb7e5230e1f3ab770d035c34928ec 527 Gene3D G3DSA:3.50.50.60 213 299 4.8E-30 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20985 392bb7e5230e1f3ab770d035c34928ec 527 Pfam PF13450 NAD(P)-binding Rossmann-like domain 8 47 5.5E-7 T 13-09-2016 THL1_RS20985 392bb7e5230e1f3ab770d035c34928ec 527 SUPERFAMILY SSF51905 472 516 4.2E-35 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20985 392bb7e5230e1f3ab770d035c34928ec 527 SUPERFAMILY SSF51905 1 304 4.2E-35 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS11870 f7a28d7fd10434ea0c5bfb77d677e94c 253 Pfam PF03412 Peptidase C39 family 57 192 5.2E-20 T 13-09-2016 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 THL1_RS11870 f7a28d7fd10434ea0c5bfb77d677e94c 253 Gene3D G3DSA:3.90.70.10 81 192 8.3E-6 T 13-09-2016 THL1_RS20110 c713e3d515266b02c648c0478b895927 431 PANTHER PTHR11056:SF0 1 431 1.5E-246 T 13-09-2016 THL1_RS20110 c713e3d515266b02c648c0478b895927 431 Pfam PF04209 homogentisate 1,2-dioxygenase 8 426 4.8E-209 T 13-09-2016 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|UniPathway: UPA00139 THL1_RS20110 c713e3d515266b02c648c0478b895927 431 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 8 428 70.881 T 13-09-2016 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|UniPathway: UPA00139 THL1_RS20110 c713e3d515266b02c648c0478b895927 431 Gene3D G3DSA:2.60.120.10 279 397 1.0E-69 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS20110 c713e3d515266b02c648c0478b895927 431 Gene3D G3DSA:2.60.120.10 193 218 1.0E-69 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS20110 c713e3d515266b02c648c0478b895927 431 PANTHER PTHR11056 1 431 1.5E-246 T 13-09-2016 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|UniPathway: UPA00139 THL1_RS20110 c713e3d515266b02c648c0478b895927 431 SUPERFAMILY SSF51182 6 428 1.91E-166 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS20110 c713e3d515266b02c648c0478b895927 431 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 7 426 5.4E-202 T 13-09-2016 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|UniPathway: UPA00139 THL1_RS05035 8aba0334545efcaafe23ed7c2e87e3f8 208 Pfam PF08682 Putative endonuclease, protein of unknown function (DUF1780) 2 208 3.9E-126 T 13-09-2016 IPR014796 Protein of unknown function DUF1780, putative endonuclease THL1_RS05035 8aba0334545efcaafe23ed7c2e87e3f8 208 SUPERFAMILY SSF52980 1 208 6.97E-111 T 13-09-2016 IPR011335 Restriction endonuclease type II-like THL1_RS05035 8aba0334545efcaafe23ed7c2e87e3f8 208 Gene3D G3DSA:3.40.1540.10 1 208 1.7E-120 T 13-09-2016 IPR014796 Protein of unknown function DUF1780, putative endonuclease THL1_RS02505 78d4c8acefbef6146475d169b9adaba2 123 PANTHER PTHR40942 1 122 1.8E-57 T 13-09-2016 THL1_RS02505 78d4c8acefbef6146475d169b9adaba2 123 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 43 117 5.6E-15 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS02505 78d4c8acefbef6146475d169b9adaba2 123 PRINTS PR00607 Class IE cytochrome C signature 64 74 4.7E-7 T 13-09-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 THL1_RS02505 78d4c8acefbef6146475d169b9adaba2 123 PRINTS PR00607 Class IE cytochrome C signature 53 64 4.7E-7 T 13-09-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 THL1_RS02505 78d4c8acefbef6146475d169b9adaba2 123 PRINTS PR00607 Class IE cytochrome C signature 107 118 4.7E-7 T 13-09-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 THL1_RS02505 78d4c8acefbef6146475d169b9adaba2 123 PRINTS PR00607 Class IE cytochrome C signature 92 104 4.7E-7 T 13-09-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 THL1_RS02505 78d4c8acefbef6146475d169b9adaba2 123 SUPERFAMILY SSF46626 48 119 1.65E-16 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS02505 78d4c8acefbef6146475d169b9adaba2 123 Gene3D G3DSA:1.10.760.10 47 119 7.6E-27 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS02505 78d4c8acefbef6146475d169b9adaba2 123 PANTHER PTHR40942:SF3 1 122 1.8E-57 T 13-09-2016 THL1_RS07015 b6d09a69566eef2c3a06e4c802050822 535 SUPERFAMILY SSF58104 227 535 1.96E-77 T 13-09-2016 THL1_RS07015 b6d09a69566eef2c3a06e4c802050822 535 SMART SM00304 206 258 3.2E-11 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS07015 b6d09a69566eef2c3a06e4c802050822 535 Pfam PF00672 HAMP domain 187 255 5.9E-13 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS07015 b6d09a69566eef2c3a06e4c802050822 535 SMART SM00283 273 534 5.1E-75 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS07015 b6d09a69566eef2c3a06e4c802050822 535 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 182 202 2.2E-25 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS07015 b6d09a69566eef2c3a06e4c802050822 535 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 400 429 2.2E-25 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS07015 b6d09a69566eef2c3a06e4c802050822 535 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 448 477 2.2E-25 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS07015 b6d09a69566eef2c3a06e4c802050822 535 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 371 398 2.2E-25 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS07015 b6d09a69566eef2c3a06e4c802050822 535 PANTHER PTHR32089 53 535 2.6E-116 T 13-09-2016 THL1_RS07015 b6d09a69566eef2c3a06e4c802050822 535 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 327 533 2.7E-54 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS07015 b6d09a69566eef2c3a06e4c802050822 535 Gene3D G3DSA:1.10.287.950 287 505 6.9E-59 T 13-09-2016 THL1_RS07655 776e6e7d4684037b6fb8488c47a1587b 295 SUPERFAMILY SSF46785 1 84 3.8E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07655 776e6e7d4684037b6fb8488c47a1587b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.8E-11 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS07655 776e6e7d4684037b6fb8488c47a1587b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.8E-11 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS07655 776e6e7d4684037b6fb8488c47a1587b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.8E-11 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS07655 776e6e7d4684037b6fb8488c47a1587b 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 3.8E-24 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS07655 776e6e7d4684037b6fb8488c47a1587b 295 Pfam PF03466 LysR substrate binding domain 88 287 1.9E-33 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS07655 776e6e7d4684037b6fb8488c47a1587b 295 PANTHER PTHR30346:SF0 1 288 4.0E-92 T 13-09-2016 THL1_RS07655 776e6e7d4684037b6fb8488c47a1587b 295 SUPERFAMILY SSF53850 91 289 2.46E-31 T 13-09-2016 THL1_RS07655 776e6e7d4684037b6fb8488c47a1587b 295 Gene3D G3DSA:3.40.190.10 173 264 1.1E-34 T 13-09-2016 THL1_RS07655 776e6e7d4684037b6fb8488c47a1587b 295 Gene3D G3DSA:3.40.190.10 87 172 1.1E-27 T 13-09-2016 THL1_RS07655 776e6e7d4684037b6fb8488c47a1587b 295 PANTHER PTHR30346 1 288 4.0E-92 T 13-09-2016 THL1_RS07655 776e6e7d4684037b6fb8488c47a1587b 295 Gene3D G3DSA:1.10.10.10 1 84 1.1E-28 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09090 83983fa4b38182a3f68d84b6c20b522e 422 Gene3D G3DSA:2.40.160.60 24 422 1.4E-132 T 13-09-2016 THL1_RS09090 83983fa4b38182a3f68d84b6c20b522e 422 PANTHER PTHR35093 1 422 2.3E-136 T 13-09-2016 THL1_RS09090 83983fa4b38182a3f68d84b6c20b522e 422 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 16 422 5.9E-123 T 13-09-2016 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) THL1_RS09090 83983fa4b38182a3f68d84b6c20b522e 422 PANTHER PTHR35093:SF2 1 422 2.3E-136 T 13-09-2016 THL1_RS09090 83983fa4b38182a3f68d84b6c20b522e 422 SUPERFAMILY SSF56935 24 422 3.36E-104 T 13-09-2016 THL1_RS09925 0dc34d2a77455fc873f1b2748c385d03 348 SUPERFAMILY SSF111369 186 266 2.35E-11 T 13-09-2016 THL1_RS09925 0dc34d2a77455fc873f1b2748c385d03 348 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 44 285 8.3E-16 T 13-09-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THL1_RS09925 0dc34d2a77455fc873f1b2748c385d03 348 Gene3D G3DSA:2.40.50.100 210 243 3.5E-17 T 13-09-2016 THL1_RS09925 0dc34d2a77455fc873f1b2748c385d03 348 Gene3D G3DSA:2.40.50.100 47 79 3.5E-17 T 13-09-2016 THL1_RS09925 0dc34d2a77455fc873f1b2748c385d03 348 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 57 77 5.4E-5 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS09925 0dc34d2a77455fc873f1b2748c385d03 348 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 329 344 5.4E-5 T 13-09-2016 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THL1_RS09925 0dc34d2a77455fc873f1b2748c385d03 348 SUPERFAMILY SSF111369 45 107 3.92E-7 T 13-09-2016 THL1_RS09925 0dc34d2a77455fc873f1b2748c385d03 348 PANTHER PTHR30386 1 339 4.2E-116 T 13-09-2016 THL1_RS09925 0dc34d2a77455fc873f1b2748c385d03 348 PANTHER PTHR30386:SF7 1 339 4.2E-116 T 13-09-2016 THL1_RS11930 085276955e7db0bb82e968f3d614cd33 243 SUPERFAMILY SSF48317 9 223 5.07E-11 T 13-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THL1_RS11930 085276955e7db0bb82e968f3d614cd33 243 Gene3D G3DSA:1.20.144.10 62 201 1.3E-7 T 13-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THL1_RS11930 085276955e7db0bb82e968f3d614cd33 243 Pfam PF01569 PAP2 superfamily 94 223 6.5E-15 T 13-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THL1_RS16855 99e2c7963ea2e462f69e4a0ac665f67d 207 Gene3D G3DSA:2.10.109.10 113 202 2.1E-7 T 13-09-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain THL1_RS16855 99e2c7963ea2e462f69e4a0ac665f67d 207 SUPERFAMILY SSF51306 111 197 3.66E-11 T 13-09-2016 IPR015927 Peptidase S24/S26A/S26B/S26C THL1_RS16855 99e2c7963ea2e462f69e4a0ac665f67d 207 Gene3D G3DSA:1.10.260.40 1 42 8.0E-8 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS16855 99e2c7963ea2e462f69e4a0ac665f67d 207 Pfam PF00717 Peptidase S24-like 124 185 1.6E-5 T 13-09-2016 IPR019759 Peptidase S24/S26A/S26B THL1_RS16855 99e2c7963ea2e462f69e4a0ac665f67d 207 SUPERFAMILY SSF47413 1 43 1.82E-5 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS16855 99e2c7963ea2e462f69e4a0ac665f67d 207 Pfam PF01381 Helix-turn-helix 1 35 1.2E-5 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS05735 e87d03d84371d2c26807e03c8703e8c7 275 SUPERFAMILY SSF82861 25 107 1.31E-16 T 13-09-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 THL1_RS05735 e87d03d84371d2c26807e03c8703e8c7 275 SUPERFAMILY SSF50182 109 174 2.06E-18 T 13-09-2016 IPR010920 LSM domain THL1_RS05735 e87d03d84371d2c26807e03c8703e8c7 275 Gene3D G3DSA:3.30.70.100 177 260 3.3E-28 T 13-09-2016 THL1_RS05735 e87d03d84371d2c26807e03c8703e8c7 275 PANTHER PTHR30221:SF7 1 275 2.9E-99 T 13-09-2016 THL1_RS05735 e87d03d84371d2c26807e03c8703e8c7 275 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 138 172 - T 13-09-2016 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 THL1_RS05735 e87d03d84371d2c26807e03c8703e8c7 275 Gene3D G3DSA:2.30.30.60 124 173 1.5E-20 T 13-09-2016 THL1_RS05735 e87d03d84371d2c26807e03c8703e8c7 275 Pfam PF00924 Mechanosensitive ion channel 67 262 1.7E-56 T 13-09-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 THL1_RS05735 e87d03d84371d2c26807e03c8703e8c7 275 Pfam PF05552 Conserved TM helix 16 59 2.4E-8 T 13-09-2016 IPR008910 Conserved TM helix THL1_RS05735 e87d03d84371d2c26807e03c8703e8c7 275 PANTHER PTHR30221 1 275 2.9E-99 T 13-09-2016 THL1_RS05735 e87d03d84371d2c26807e03c8703e8c7 275 SUPERFAMILY SSF82689 176 272 2.22E-30 T 13-09-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 THL1_RS14285 68c9768a639d15220737ab7a57bd99f1 387 Gene3D G3DSA:1.20.1090.10 189 387 3.0E-61 T 13-09-2016 THL1_RS14285 68c9768a639d15220737ab7a57bd99f1 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 15 379 1.1E-114 T 13-09-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 THL1_RS14285 68c9768a639d15220737ab7a57bd99f1 387 PANTHER PTHR11496:SF79 12 386 2.3E-143 T 13-09-2016 THL1_RS14285 68c9768a639d15220737ab7a57bd99f1 387 PANTHER PTHR11496 12 386 2.3E-143 T 13-09-2016 THL1_RS14285 68c9768a639d15220737ab7a57bd99f1 387 SUPERFAMILY SSF56796 11 385 8.24E-119 T 13-09-2016 THL1_RS14285 68c9768a639d15220737ab7a57bd99f1 387 Gene3D G3DSA:3.40.50.1970 12 187 1.5E-55 T 13-09-2016 THL1_RS14285 68c9768a639d15220737ab7a57bd99f1 387 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 264 284 - T 13-09-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 THL1_RS26260 74f1972082210ade3cfebf2515f8ab12 274 PANTHER PTHR31964 1 146 9.3E-17 T 13-09-2016 THL1_RS26260 74f1972082210ade3cfebf2515f8ab12 274 Pfam PF00582 Universal stress protein family 1 128 1.1E-24 T 13-09-2016 IPR006016 UspA GO:0006950 THL1_RS26260 74f1972082210ade3cfebf2515f8ab12 274 Pfam PF00582 Universal stress protein family 137 274 3.7E-12 T 13-09-2016 IPR006016 UspA GO:0006950 THL1_RS26260 74f1972082210ade3cfebf2515f8ab12 274 SUPERFAMILY SSF52402 137 274 3.93E-13 T 13-09-2016 THL1_RS26260 74f1972082210ade3cfebf2515f8ab12 274 PANTHER PTHR31964:SF42 1 146 9.3E-17 T 13-09-2016 THL1_RS26260 74f1972082210ade3cfebf2515f8ab12 274 Gene3D G3DSA:3.40.50.620 1 127 1.8E-28 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS26260 74f1972082210ade3cfebf2515f8ab12 274 PRINTS PR01438 Universal stress protein signature 90 102 4.3E-9 T 13-09-2016 IPR006015 Universal stress protein A THL1_RS26260 74f1972082210ade3cfebf2515f8ab12 274 PRINTS PR01438 Universal stress protein signature 2 20 4.3E-9 T 13-09-2016 IPR006015 Universal stress protein A THL1_RS26260 74f1972082210ade3cfebf2515f8ab12 274 PRINTS PR01438 Universal stress protein signature 107 129 4.3E-9 T 13-09-2016 IPR006015 Universal stress protein A THL1_RS26260 74f1972082210ade3cfebf2515f8ab12 274 Gene3D G3DSA:3.40.50.620 128 274 6.8E-16 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS26260 74f1972082210ade3cfebf2515f8ab12 274 SUPERFAMILY SSF52402 1 128 1.26E-27 T 13-09-2016 THL1_RS10430 46e77d6e8ff8f28e84405501adad1d1e 185 SUPERFAMILY SSF48498 75 180 3.68E-17 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS10430 46e77d6e8ff8f28e84405501adad1d1e 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 3.6E-9 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS10430 46e77d6e8ff8f28e84405501adad1d1e 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 3.6E-9 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS10430 46e77d6e8ff8f28e84405501adad1d1e 185 Gene3D G3DSA:1.10.357.10 4 180 2.1E-35 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS10430 46e77d6e8ff8f28e84405501adad1d1e 185 SUPERFAMILY SSF46689 3 78 6.98E-18 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS10430 46e77d6e8ff8f28e84405501adad1d1e 185 PANTHER PTHR30055 2 183 3.4E-40 T 13-09-2016 THL1_RS10430 46e77d6e8ff8f28e84405501adad1d1e 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 1.1E-14 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS10430 46e77d6e8ff8f28e84405501adad1d1e 185 PANTHER PTHR30055:SF47 2 183 3.4E-40 T 13-09-2016 THL1_RS02650 1f2ce9edc884a6f8ff41b5a546a1060a 209 SUPERFAMILY SSF52172 2 132 7.68E-33 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS02650 1f2ce9edc884a6f8ff41b5a546a1060a 209 Gene3D G3DSA:1.10.10.10 121 209 2.7E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02650 1f2ce9edc884a6f8ff41b5a546a1060a 209 PANTHER PTHR26402 2 205 1.8E-92 T 13-09-2016 THL1_RS02650 1f2ce9edc884a6f8ff41b5a546a1060a 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 4.4E-18 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS02650 1f2ce9edc884a6f8ff41b5a546a1060a 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 2.5E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS02650 1f2ce9edc884a6f8ff41b5a546a1060a 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 2.5E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS02650 1f2ce9edc884a6f8ff41b5a546a1060a 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 2.5E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS02650 1f2ce9edc884a6f8ff41b5a546a1060a 209 Gene3D G3DSA:3.40.50.2300 2 120 3.5E-35 T 13-09-2016 THL1_RS02650 1f2ce9edc884a6f8ff41b5a546a1060a 209 SMART SM00421 146 203 1.2E-18 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS02650 1f2ce9edc884a6f8ff41b5a546a1060a 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS02650 1f2ce9edc884a6f8ff41b5a546a1060a 209 Pfam PF00072 Response regulator receiver domain 4 116 4.2E-26 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02650 1f2ce9edc884a6f8ff41b5a546a1060a 209 SMART SM00448 2 115 1.1E-28 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02650 1f2ce9edc884a6f8ff41b5a546a1060a 209 PANTHER PTHR26402:SF598 2 205 1.8E-92 T 13-09-2016 THL1_RS02650 1f2ce9edc884a6f8ff41b5a546a1060a 209 SUPERFAMILY SSF46894 136 208 1.73E-18 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS11515 8b5c3d7935db450c9370468022dabbe8 248 PANTHER PTHR30269:SF9 1 248 9.2E-59 T 13-09-2016 THL1_RS11515 8b5c3d7935db450c9370468022dabbe8 248 PANTHER PTHR30269 1 248 9.2E-59 T 13-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 THL1_RS11515 8b5c3d7935db450c9370468022dabbe8 248 Pfam PF01925 Sulfite exporter TauE/SafE 9 244 5.0E-44 T 13-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 SUPERFAMILY SSF52922 694 879 9.07E-61 T 13-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 PIRSF PIRSF000156 1 881 0.0 T 13-09-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 Gene3D G3DSA:3.40.50.970 51 460 1.3E-153 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 PANTHER PTHR11624 356 447 0.0 T 13-09-2016 IPR033247 Transketolase family THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 PANTHER PTHR11624 779 863 0.0 T 13-09-2016 IPR033247 Transketolase family THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 PANTHER PTHR11624 464 527 0.0 T 13-09-2016 IPR033247 Transketolase family THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 PANTHER PTHR11624 545 760 0.0 T 13-09-2016 IPR033247 Transketolase family THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 PANTHER PTHR11624 69 288 0.0 T 13-09-2016 IPR033247 Transketolase family THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 PANTHER PTHR11624:SF72 356 447 0.0 T 13-09-2016 THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 PANTHER PTHR11624:SF72 545 760 0.0 T 13-09-2016 THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 Gene3D G3DSA:3.40.50.920 698 879 5.9E-79 T 13-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 SUPERFAMILY SSF52518 465 692 2.94E-95 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 PANTHER PTHR11624:SF72 779 863 0.0 T 13-09-2016 THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 PANTHER PTHR11624:SF72 464 527 0.0 T 13-09-2016 THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 PANTHER PTHR11624:SF72 69 288 0.0 T 13-09-2016 THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 131 287 2.7E-7 T 13-09-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 Gene3D G3DSA:3.40.50.970 465 696 1.6E-118 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 2 879 0.0 T 13-09-2016 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 THL1_RS26190 42de95924c26d00ba832d35e84b2f1a5 881 SUPERFAMILY SSF52518 52 458 8.58E-136 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS11340 50aa2046206f3657b7d1f07400647276 265 SUPERFAMILY SSF46626 159 262 1.41E-16 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS11340 50aa2046206f3657b7d1f07400647276 265 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 173 255 9.3E-9 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS11340 50aa2046206f3657b7d1f07400647276 265 Gene3D G3DSA:1.10.760.10 162 262 1.3E-14 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS07110 f318f53c9978fe72271b55e388400aa2 385 Gene3D G3DSA:1.20.140.10 213 384 1.6E-35 T 13-09-2016 THL1_RS07110 f318f53c9978fe72271b55e388400aa2 385 SUPERFAMILY SSF56645 2 222 7.85E-40 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS07110 f318f53c9978fe72271b55e388400aa2 385 Gene3D G3DSA:2.40.110.10 137 212 1.4E-7 T 13-09-2016 THL1_RS07110 f318f53c9978fe72271b55e388400aa2 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 223 380 5.5E-25 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS07110 f318f53c9978fe72271b55e388400aa2 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 3.5E-22 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS07110 f318f53c9978fe72271b55e388400aa2 385 PANTHER PTHR10909 1 382 1.6E-92 T 13-09-2016 THL1_RS07110 f318f53c9978fe72271b55e388400aa2 385 SUPERFAMILY SSF47203 224 383 4.51E-36 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS07110 f318f53c9978fe72271b55e388400aa2 385 PANTHER PTHR10909:SF302 1 382 1.6E-92 T 13-09-2016 THL1_RS07110 f318f53c9978fe72271b55e388400aa2 385 Gene3D G3DSA:1.10.540.10 1 119 3.8E-24 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS02795 95175d702ef6fb4c74a9f061d8dde421 391 Gene3D G3DSA:2.40.160.10 48 275 2.6E-5 T 13-09-2016 IPR023614 Porin domain THL1_RS02795 95175d702ef6fb4c74a9f061d8dde421 391 SUPERFAMILY SSF56935 26 169 4.94E-5 T 13-09-2016 THL1_RS02795 95175d702ef6fb4c74a9f061d8dde421 391 SUPERFAMILY SSF56935 213 365 4.94E-5 T 13-09-2016 THL1_RS02200 1faec394dde115719d69d5444877a692 430 Pfam PF00990 Diguanylate cyclase, GGDEF domain 366 411 4.2E-8 T 13-09-2016 IPR000160 GGDEF domain THL1_RS02200 1faec394dde115719d69d5444877a692 430 Pfam PF00990 Diguanylate cyclase, GGDEF domain 242 347 1.6E-24 T 13-09-2016 IPR000160 GGDEF domain THL1_RS02200 1faec394dde115719d69d5444877a692 430 SUPERFAMILY SSF55073 247 415 3.14E-40 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS02200 1faec394dde115719d69d5444877a692 430 SMART SM00267 232 415 3.5E-46 T 13-09-2016 IPR000160 GGDEF domain THL1_RS02200 1faec394dde115719d69d5444877a692 430 PANTHER PTHR10799 269 348 1.6E-19 T 13-09-2016 THL1_RS02200 1faec394dde115719d69d5444877a692 430 PANTHER PTHR10799 374 411 1.6E-19 T 13-09-2016 THL1_RS02200 1faec394dde115719d69d5444877a692 430 Gene3D G3DSA:3.30.70.270 244 413 4.4E-46 T 13-09-2016 THL1_RS02200 1faec394dde115719d69d5444877a692 430 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 367 413 1.5E-10 T 13-09-2016 IPR000160 GGDEF domain THL1_RS02200 1faec394dde115719d69d5444877a692 430 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 240 348 4.8E-26 T 13-09-2016 IPR000160 GGDEF domain THL1_RS20340 927662249a00308cf2808aedcde84707 95 Pfam PF02583 Metal-sensitive transcriptional repressor 13 91 7.4E-23 T 13-09-2016 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 THL1_RS20340 927662249a00308cf2808aedcde84707 95 PANTHER PTHR33677 3 95 9.9E-17 T 13-09-2016 THL1_RS20340 927662249a00308cf2808aedcde84707 95 PANTHER PTHR33677:SF3 3 95 9.9E-17 T 13-09-2016 THL1_RS26500 23bdc4f8ce3c31c36df63e36aa671e01 157 SUPERFAMILY SSF55811 5 133 5.42E-23 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS26500 23bdc4f8ce3c31c36df63e36aa671e01 157 PANTHER PTHR22769 8 140 2.1E-18 T 13-09-2016 THL1_RS26500 23bdc4f8ce3c31c36df63e36aa671e01 157 Pfam PF00293 NUDIX domain 9 129 7.5E-14 T 13-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 THL1_RS26500 23bdc4f8ce3c31c36df63e36aa671e01 157 Gene3D G3DSA:3.90.79.10 6 135 3.2E-28 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS02065 35d4fbc1ffed78e5ec220f438898681a 225 Pfam PF11075 Protein of unknown function VcgC/VcgE (DUF2780) 12 186 2.1E-39 T 13-09-2016 IPR021302 Protein of unknown function DUF2780, VcgC/VcgE THL1_RS06560 1fb77b118b81432f8d1ee2231deb7f35 498 PANTHER PTHR11751 112 498 1.1E-108 T 13-09-2016 THL1_RS06560 1fb77b118b81432f8d1ee2231deb7f35 498 SUPERFAMILY SSF46785 15 87 2.02E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS06560 1fb77b118b81432f8d1ee2231deb7f35 498 PANTHER PTHR11751:SF10 112 498 1.1E-108 T 13-09-2016 THL1_RS06560 1fb77b118b81432f8d1ee2231deb7f35 498 Gene3D G3DSA:1.10.10.10 12 85 1.6E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS06560 1fb77b118b81432f8d1ee2231deb7f35 498 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 1.2E-5 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS06560 1fb77b118b81432f8d1ee2231deb7f35 498 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 1.2E-5 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS06560 1fb77b118b81432f8d1ee2231deb7f35 498 Pfam PF00155 Aminotransferase class I and II 147 453 1.1E-20 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS06560 1fb77b118b81432f8d1ee2231deb7f35 498 SMART SM00345 26 85 9.7E-12 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS06560 1fb77b118b81432f8d1ee2231deb7f35 498 SUPERFAMILY SSF53383 129 493 2.07E-85 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS06560 1fb77b118b81432f8d1ee2231deb7f35 498 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 85 4.4E-13 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS06560 1fb77b118b81432f8d1ee2231deb7f35 498 Gene3D G3DSA:3.40.640.10 163 382 1.8E-53 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS17160 2af6dba9a4f0e118d0de7b34790fcf69 218 SUPERFAMILY SSF46626 130 212 7.48E-18 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS17160 2af6dba9a4f0e118d0de7b34790fcf69 218 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 54 116 3.0E-6 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS17160 2af6dba9a4f0e118d0de7b34790fcf69 218 Gene3D G3DSA:1.10.760.10 128 213 1.0E-21 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS17160 2af6dba9a4f0e118d0de7b34790fcf69 218 PANTHER PTHR33751 17 215 7.4E-43 T 13-09-2016 THL1_RS17160 2af6dba9a4f0e118d0de7b34790fcf69 218 Gene3D G3DSA:1.10.760.10 51 121 6.2E-25 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS17160 2af6dba9a4f0e118d0de7b34790fcf69 218 PANTHER PTHR33751:SF3 17 215 7.4E-43 T 13-09-2016 THL1_RS17160 2af6dba9a4f0e118d0de7b34790fcf69 218 PIRSF PIRSF000005 1 215 4.2E-51 T 13-09-2016 IPR024167 Cytochrome c4 GO:0005506|GO:0009055|GO:0020037|GO:0042597 THL1_RS17160 2af6dba9a4f0e118d0de7b34790fcf69 218 Pfam PF00034 Cytochrome c 136 211 1.3E-8 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS17160 2af6dba9a4f0e118d0de7b34790fcf69 218 SUPERFAMILY SSF46626 52 120 3.41E-19 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS14485 85c6e797caa8e4ccf3130175331fb138 480 PANTHER PTHR11699:SF200 6 480 9.9E-239 T 13-09-2016 THL1_RS14485 85c6e797caa8e4ccf3130175331fb138 480 Gene3D G3DSA:3.40.605.10 6 262 1.9E-82 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS14485 85c6e797caa8e4ccf3130175331fb138 480 SUPERFAMILY SSF53720 5 479 3.67E-155 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS14485 85c6e797caa8e4ccf3130175331fb138 480 PANTHER PTHR11699 6 480 9.9E-239 T 13-09-2016 THL1_RS14485 85c6e797caa8e4ccf3130175331fb138 480 Pfam PF00171 Aldehyde dehydrogenase family 14 476 7.9E-158 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS14485 85c6e797caa8e4ccf3130175331fb138 480 Gene3D G3DSA:3.40.309.10 263 450 1.9E-65 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS11140 4903cd06b673768bfc6def3269ef63ff 405 Gene3D G3DSA:1.20.1250.20 220 400 4.4E-16 T 13-09-2016 THL1_RS11140 4903cd06b673768bfc6def3269ef63ff 405 Gene3D G3DSA:1.20.1250.20 27 202 2.6E-22 T 13-09-2016 THL1_RS11140 4903cd06b673768bfc6def3269ef63ff 405 PANTHER PTHR23501:SF28 24 401 2.1E-188 T 13-09-2016 THL1_RS11140 4903cd06b673768bfc6def3269ef63ff 405 Pfam PF07690 Major Facilitator Superfamily 31 343 2.8E-25 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS11140 4903cd06b673768bfc6def3269ef63ff 405 SUPERFAMILY SSF103473 5 398 1.44E-55 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS11140 4903cd06b673768bfc6def3269ef63ff 405 PANTHER PTHR23501 24 401 2.1E-188 T 13-09-2016 THL1_RS25495 85d780f0f2e539c8f968033a8eea749f 535 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 10 535 44.773 T 13-09-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 THL1_RS25495 85d780f0f2e539c8f968033a8eea749f 535 Gene3D G3DSA:3.40.140.20 383 525 1.8E-61 T 13-09-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 THL1_RS25495 85d780f0f2e539c8f968033a8eea749f 535 Gene3D G3DSA:3.40.140.20 254 377 4.9E-45 T 13-09-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 THL1_RS25495 85d780f0f2e539c8f968033a8eea749f 535 Pfam PF02142 MGS-like domain 22 135 3.5E-27 T 13-09-2016 IPR011607 Methylglyoxal synthase-like domain THL1_RS25495 85d780f0f2e539c8f968033a8eea749f 535 PANTHER PTHR11692 8 535 0.0 T 13-09-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 THL1_RS25495 85d780f0f2e539c8f968033a8eea749f 535 PIRSF PIRSF000414 4 535 9.4E-217 T 13-09-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 THL1_RS25495 85d780f0f2e539c8f968033a8eea749f 535 Gene3D G3DSA:3.40.50.1380 9 191 5.4E-81 T 13-09-2016 IPR011607 Methylglyoxal synthase-like domain THL1_RS25495 85d780f0f2e539c8f968033a8eea749f 535 SUPERFAMILY SSF53927 222 535 1.5E-127 T 13-09-2016 IPR016193 Cytidine deaminase-like GO:0003824 THL1_RS25495 85d780f0f2e539c8f968033a8eea749f 535 SUPERFAMILY SSF52335 10 197 2.35E-68 T 13-09-2016 IPR011607 Methylglyoxal synthase-like domain THL1_RS25495 85d780f0f2e539c8f968033a8eea749f 535 PANTHER PTHR11692:SF2 8 535 0.0 T 13-09-2016 THL1_RS25495 85d780f0f2e539c8f968033a8eea749f 535 SMART SM00798 140 467 3.6E-205 T 13-09-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 THL1_RS25495 85d780f0f2e539c8f968033a8eea749f 535 SMART SM00851 22 135 1.9E-58 T 13-09-2016 IPR011607 Methylglyoxal synthase-like domain THL1_RS25495 85d780f0f2e539c8f968033a8eea749f 535 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 11 535 2.7E-234 T 13-09-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 THL1_RS25495 85d780f0f2e539c8f968033a8eea749f 535 Pfam PF01808 AICARFT/IMPCHase bienzyme 140 466 7.3E-115 T 13-09-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 THL1_RS18395 0e294aff2c07dd27baafaa9f5e437173 386 PANTHER PTHR10909 1 385 1.8E-298 T 13-09-2016 THL1_RS18395 0e294aff2c07dd27baafaa9f5e437173 386 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS18395 0e294aff2c07dd27baafaa9f5e437173 386 PANTHER PTHR10909:SF325 1 385 1.8E-298 T 13-09-2016 THL1_RS18395 0e294aff2c07dd27baafaa9f5e437173 386 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS18395 0e294aff2c07dd27baafaa9f5e437173 386 Gene3D G3DSA:2.40.110.10 121 218 1.4E-38 T 13-09-2016 THL1_RS18395 0e294aff2c07dd27baafaa9f5e437173 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 375 1.9E-43 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS18395 0e294aff2c07dd27baafaa9f5e437173 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 118 3.0E-32 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS18395 0e294aff2c07dd27baafaa9f5e437173 386 SUPERFAMILY SSF47203 229 377 1.29E-43 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS18395 0e294aff2c07dd27baafaa9f5e437173 386 Gene3D G3DSA:1.10.540.10 3 119 2.6E-36 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS18395 0e294aff2c07dd27baafaa9f5e437173 386 Gene3D G3DSA:1.20.140.10 219 381 9.3E-55 T 13-09-2016 THL1_RS18395 0e294aff2c07dd27baafaa9f5e437173 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 6.4E-24 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS18395 0e294aff2c07dd27baafaa9f5e437173 386 SUPERFAMILY SSF56645 2 241 1.57E-80 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS05705 c93682e6fd0b8c10c75b6cdebceff3e7 151 Gene3D G3DSA:3.30.70.1290 7 132 5.7E-19 T 13-09-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THL1_RS05705 c93682e6fd0b8c10c75b6cdebceff3e7 151 Pfam PF01797 Transposase IS200 like 21 129 7.8E-15 T 13-09-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THL1_RS05705 c93682e6fd0b8c10c75b6cdebceff3e7 151 SMART SM01321 16 130 4.7E-34 T 13-09-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THL1_RS05705 c93682e6fd0b8c10c75b6cdebceff3e7 151 PANTHER PTHR36966 7 151 1.4E-25 T 13-09-2016 THL1_RS05705 c93682e6fd0b8c10c75b6cdebceff3e7 151 PANTHER PTHR36966:SF1 7 151 1.4E-25 T 13-09-2016 THL1_RS05705 c93682e6fd0b8c10c75b6cdebceff3e7 151 SUPERFAMILY SSF143422 9 136 1.57E-28 T 13-09-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THL1_RS12385 2d2e44b22b945d4025a2ba5eda04eb12 72 Gene3D G3DSA:2.40.50.140 1 71 1.1E-38 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS12385 2d2e44b22b945d4025a2ba5eda04eb12 72 Pfam PF01176 Translation initiation factor 1A / IF-1 8 70 1.3E-27 T 13-09-2016 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 THL1_RS12385 2d2e44b22b945d4025a2ba5eda04eb12 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 4.6E-38 T 13-09-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 THL1_RS12385 2d2e44b22b945d4025a2ba5eda04eb12 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.956 T 13-09-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 THL1_RS12385 2d2e44b22b945d4025a2ba5eda04eb12 72 SMART SM00316 4 72 2.4E-6 T 13-09-2016 IPR022967 RNA-binding domain, S1 THL1_RS12385 2d2e44b22b945d4025a2ba5eda04eb12 72 PANTHER PTHR33370 1 72 1.2E-48 T 13-09-2016 THL1_RS12385 2d2e44b22b945d4025a2ba5eda04eb12 72 SUPERFAMILY SSF50249 1 70 1.29E-28 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS24930 a053e49654f7cc6ece30b7c98946af0a 498 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 6 481 2.4E-211 T 13-09-2016 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373 THL1_RS24930 a053e49654f7cc6ece30b7c98946af0a 498 PANTHER PTHR11699 4 483 0.0 T 13-09-2016 THL1_RS24930 a053e49654f7cc6ece30b7c98946af0a 498 PANTHER PTHR11699:SF188 4 483 0.0 T 13-09-2016 THL1_RS24930 a053e49654f7cc6ece30b7c98946af0a 498 Gene3D G3DSA:3.40.605.10 4 259 6.4E-89 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS24930 a053e49654f7cc6ece30b7c98946af0a 498 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 273 284 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS24930 a053e49654f7cc6ece30b7c98946af0a 498 Pfam PF00171 Aldehyde dehydrogenase family 16 477 1.5E-140 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS24930 a053e49654f7cc6ece30b7c98946af0a 498 Gene3D G3DSA:3.40.309.10 260 442 6.3E-66 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS24930 a053e49654f7cc6ece30b7c98946af0a 498 SUPERFAMILY SSF53720 2 483 4.45E-150 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS11015 46a7573ffa84ba8170d02ca34863ef48 147 SUPERFAMILY SSF54637 19 143 5.3E-30 T 13-09-2016 IPR029069 HotDog domain THL1_RS11015 46a7573ffa84ba8170d02ca34863ef48 147 Pfam PF03061 Thioesterase superfamily 51 126 1.2E-13 T 13-09-2016 IPR006683 Thioesterase domain THL1_RS11015 46a7573ffa84ba8170d02ca34863ef48 147 PANTHER PTHR12418 25 138 8.8E-48 T 13-09-2016 THL1_RS11015 46a7573ffa84ba8170d02ca34863ef48 147 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 23 136 1.5E-34 T 13-09-2016 IPR003736 Phenylacetic acid degradation-related domain THL1_RS11015 46a7573ffa84ba8170d02ca34863ef48 147 Gene3D G3DSA:3.10.129.10 3 139 3.7E-44 T 13-09-2016 IPR029069 HotDog domain THL1_RS11015 46a7573ffa84ba8170d02ca34863ef48 147 PANTHER PTHR12418:SF33 25 138 8.8E-48 T 13-09-2016 THL1_RS09135 370c259df35e13a4f0526a7c8f7273e5 309 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 102 273 9.0E-43 T 13-09-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 THL1_RS09135 370c259df35e13a4f0526a7c8f7273e5 309 PANTHER PTHR10996:SF148 43 307 2.0E-98 T 13-09-2016 THL1_RS09135 370c259df35e13a4f0526a7c8f7273e5 309 Gene3D G3DSA:3.40.50.720 95 274 3.4E-48 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS09135 370c259df35e13a4f0526a7c8f7273e5 309 SUPERFAMILY SSF51735 94 274 2.84E-43 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS09135 370c259df35e13a4f0526a7c8f7273e5 309 PANTHER PTHR10996 43 307 2.0E-98 T 13-09-2016 THL1_RS12670 30407804778e55655d4de0a7c2335206 222 Gene3D G3DSA:1.10.357.10 82 218 4.5E-28 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS12670 30407804778e55655d4de0a7c2335206 222 PANTHER PTHR30328:SF16 12 221 2.5E-107 T 13-09-2016 THL1_RS12670 30407804778e55655d4de0a7c2335206 222 SUPERFAMILY SSF48498 96 221 2.5E-36 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS12670 30407804778e55655d4de0a7c2335206 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 76 3.3E-14 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS12670 30407804778e55655d4de0a7c2335206 222 Gene3D G3DSA:1.10.10.60 15 59 3.2E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS12670 30407804778e55655d4de0a7c2335206 222 SUPERFAMILY SSF46689 17 92 4.41E-19 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS12670 30407804778e55655d4de0a7c2335206 222 PANTHER PTHR30328 12 221 2.5E-107 T 13-09-2016 THL1_RS12670 30407804778e55655d4de0a7c2335206 222 Gene3D G3DSA:1.10.10.60 60 81 1.8E-6 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS12670 30407804778e55655d4de0a7c2335206 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 1.3E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS12670 30407804778e55655d4de0a7c2335206 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 1.3E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS21480 2cba5949ae65b5bd2a83330bd229703d 81 Pfam PF06611 Protein of unknown function (DUF1145) 8 58 1.1E-15 T 13-09-2016 IPR009525 Protein of unknown function DUF1145 THL1_RS21480 2cba5949ae65b5bd2a83330bd229703d 81 PANTHER PTHR38775 1 81 1.6E-20 T 13-09-2016 THL1_RS21480 2cba5949ae65b5bd2a83330bd229703d 81 PANTHER PTHR38775:SF1 1 81 1.6E-20 T 13-09-2016 THL1_RS16665 ae8cb94df79ecfde5398cf2a062c7fa3 111 PANTHER PTHR36455 2 97 7.3E-16 T 13-09-2016 THL1_RS16665 ae8cb94df79ecfde5398cf2a062c7fa3 111 Pfam PF05717 IS66 Orf2 like protein 6 102 8.3E-29 T 13-09-2016 IPR008878 Transposase IS66, Orf2 THL1_RS16665 ae8cb94df79ecfde5398cf2a062c7fa3 111 PANTHER PTHR36455:SF1 2 97 7.3E-16 T 13-09-2016 THL1_RS09715 a019f21cc8b35e98c3df046790c8859d 508 PANTHER PTHR11785 1 477 3.2E-66 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS09715 a019f21cc8b35e98c3df046790c8859d 508 Pfam PF13520 Amino acid permease 34 463 3.2E-45 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS09715 a019f21cc8b35e98c3df046790c8859d 508 PIRSF PIRSF006060 9 488 8.6E-61 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS16205 7d773fb3ee8819f1b505c65a2e6a164b 102 Pfam PF10109 Phage tail assembly chaperone proteins, E, or 41 or 14 10 89 5.7E-14 T 13-09-2016 IPR019289 Bacteriophage tail protein Gp41, putative THL1_RS21500 50539e9d0690c7620c18cce0f7326054 355 Gene3D G3DSA:3.40.190.10 126 235 2.7E-12 T 13-09-2016 THL1_RS21500 50539e9d0690c7620c18cce0f7326054 355 TIGRFAM TIGR03427 ABC_peri_uca: ABC transporter periplasmic binding protein, urea carboxylase region 27 355 1.3E-171 T 13-09-2016 IPR017793 ABC transporter, urea utilisation-associated, substrate-binding protein THL1_RS21500 50539e9d0690c7620c18cce0f7326054 355 Pfam PF09084 NMT1/THI5 like 56 237 8.6E-9 T 13-09-2016 IPR015168 SsuA/THI5-like THL1_RS21500 50539e9d0690c7620c18cce0f7326054 355 PANTHER PTHR30024 5 280 5.0E-12 T 13-09-2016 THL1_RS21500 50539e9d0690c7620c18cce0f7326054 355 SUPERFAMILY SSF53850 33 263 3.04E-36 T 13-09-2016 THL1_RS28130 5a6e01bccbb06e3ded5655593c2797ea 302 PANTHER PTHR30126:SF2 2 295 2.1E-141 T 13-09-2016 THL1_RS28130 5a6e01bccbb06e3ded5655593c2797ea 302 Gene3D G3DSA:3.40.190.10 200 262 4.7E-8 T 13-09-2016 THL1_RS28130 5a6e01bccbb06e3ded5655593c2797ea 302 SUPERFAMILY SSF53850 93 296 1.43E-23 T 13-09-2016 THL1_RS28130 5a6e01bccbb06e3ded5655593c2797ea 302 Gene3D G3DSA:3.40.190.10 85 199 1.2E-8 T 13-09-2016 THL1_RS28130 5a6e01bccbb06e3ded5655593c2797ea 302 Pfam PF03466 LysR substrate binding domain 90 294 1.1E-28 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS28130 5a6e01bccbb06e3ded5655593c2797ea 302 SUPERFAMILY SSF46785 4 89 7.22E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS28130 5a6e01bccbb06e3ded5655593c2797ea 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.0E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS28130 5a6e01bccbb06e3ded5655593c2797ea 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.0E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS28130 5a6e01bccbb06e3ded5655593c2797ea 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.0E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS28130 5a6e01bccbb06e3ded5655593c2797ea 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.1E-17 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS28130 5a6e01bccbb06e3ded5655593c2797ea 302 Gene3D G3DSA:1.10.10.10 4 84 1.9E-27 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS28130 5a6e01bccbb06e3ded5655593c2797ea 302 PANTHER PTHR30126 2 295 2.1E-141 T 13-09-2016 THL1_RS06485 3eff80d1b14a0ee16033bd7883b294ac 348 SUPERFAMILY SSF50022 9 126 1.57E-30 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS06485 3eff80d1b14a0ee16033bd7883b294ac 348 PANTHER PTHR21266 6 328 2.4E-74 T 13-09-2016 THL1_RS06485 3eff80d1b14a0ee16033bd7883b294ac 348 Pfam PF00355 Rieske [2Fe-2S] domain 20 102 1.1E-14 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS06485 3eff80d1b14a0ee16033bd7883b294ac 348 PANTHER PTHR21266:SF31 6 328 2.4E-74 T 13-09-2016 THL1_RS06485 3eff80d1b14a0ee16033bd7883b294ac 348 SUPERFAMILY SSF55961 119 328 9.16E-23 T 13-09-2016 THL1_RS06485 3eff80d1b14a0ee16033bd7883b294ac 348 Gene3D G3DSA:2.102.10.10 18 131 4.3E-31 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS12015 fdca483e241d48310e271096899fe65d 117 Pfam PF12021 Protein of unknown function (DUF3509) 8 72 2.5E-9 T 13-09-2016 IPR021898 Protein of unknown function DUF3509 THL1_RS09605 cf539a8ce1eaba54a370ee73d0cec857 474 SUPERFAMILY SSF52540 102 437 3.28E-61 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09605 cf539a8ce1eaba54a370ee73d0cec857 474 Gene3D G3DSA:3.30.450.90 118 215 3.6E-36 T 13-09-2016 THL1_RS09605 cf539a8ce1eaba54a370ee73d0cec857 474 Pfam PF00437 Type II/IV secretion system protein 121 398 9.0E-85 T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS09605 cf539a8ce1eaba54a370ee73d0cec857 474 PANTHER PTHR30258:SF3 42 461 4.8E-130 T 13-09-2016 THL1_RS09605 cf539a8ce1eaba54a370ee73d0cec857 474 Gene3D G3DSA:3.40.50.300 223 431 1.2E-64 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09605 cf539a8ce1eaba54a370ee73d0cec857 474 PANTHER PTHR30258 42 461 4.8E-130 T 13-09-2016 THL1_RS12320 da8e1b7b03b1cbb944f03dea685172a2 269 Pfam PF00263 Bacterial type II and III secretion system protein 141 243 1.6E-5 T 13-09-2016 IPR004846 Type II/III secretion system GO:0009306 THL1_RS12320 da8e1b7b03b1cbb944f03dea685172a2 269 Pfam PF03958 Bacterial type II/III secretion system short domain 22 80 5.4E-10 T 13-09-2016 IPR005644 NolW-like THL1_RS19930 b3add743708ac1e076dda5ff027e4f4b 69 SMART SM00357 6 69 5.6E-27 T 13-09-2016 IPR011129 Cold shock protein GO:0003676 THL1_RS19930 b3add743708ac1e076dda5ff027e4f4b 69 Gene3D G3DSA:2.40.50.140 5 68 5.6E-30 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS19930 b3add743708ac1e076dda5ff027e4f4b 69 SUPERFAMILY SSF50249 5 68 5.57E-23 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS19930 b3add743708ac1e076dda5ff027e4f4b 69 PIRSF PIRSF002599 1 69 1.2E-23 T 13-09-2016 IPR012156 Cold shock, CspA GO:0003676 THL1_RS19930 b3add743708ac1e076dda5ff027e4f4b 69 Pfam PF00313 'Cold-shock' DNA-binding domain 6 68 1.1E-27 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS19930 b3add743708ac1e076dda5ff027e4f4b 69 PANTHER PTHR11544:SF63 1 68 4.7E-36 T 13-09-2016 THL1_RS19930 b3add743708ac1e076dda5ff027e4f4b 69 ProSitePatterns PS00352 'Cold-shock' domain signature. 18 36 - T 13-09-2016 IPR019844 Cold-shock conserved site THL1_RS19930 b3add743708ac1e076dda5ff027e4f4b 69 PRINTS PR00050 Cold shock protein signature 42 60 1.3E-17 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS19930 b3add743708ac1e076dda5ff027e4f4b 69 PRINTS PR00050 Cold shock protein signature 7 22 1.3E-17 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS19930 b3add743708ac1e076dda5ff027e4f4b 69 PRINTS PR00050 Cold shock protein signature 27 36 1.3E-17 T 13-09-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THL1_RS19930 b3add743708ac1e076dda5ff027e4f4b 69 PANTHER PTHR11544 1 68 4.7E-36 T 13-09-2016 THL1_RS12955 1b2e8a968bd93e7ea30edddd96adb18e 166 PANTHER PTHR23339:SF64 4 162 2.0E-22 T 13-09-2016 THL1_RS12955 1b2e8a968bd93e7ea30edddd96adb18e 166 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 111 121 - T 13-09-2016 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311|GO:0016791 THL1_RS12955 1b2e8a968bd93e7ea30edddd96adb18e 166 Pfam PF00782 Dual specificity phosphatase, catalytic domain 67 162 4.8E-7 T 13-09-2016 IPR000340 Dual specificity phosphatase, catalytic domain GO:0006470|GO:0008138 THL1_RS12955 1b2e8a968bd93e7ea30edddd96adb18e 166 PANTHER PTHR23339 4 162 2.0E-22 T 13-09-2016 THL1_RS12955 1b2e8a968bd93e7ea30edddd96adb18e 166 SUPERFAMILY SSF52799 5 162 3.13E-32 T 13-09-2016 IPR029021 Protein-tyrosine phosphatase-like THL1_RS12955 1b2e8a968bd93e7ea30edddd96adb18e 166 Gene3D G3DSA:3.90.190.10 8 162 4.1E-37 T 13-09-2016 IPR029021 Protein-tyrosine phosphatase-like THL1_RS12170 3b8d59801ad6e60a0c1a0776cbd65ced 255 PANTHER PTHR10264:SF60 10 242 9.3E-109 T 13-09-2016 THL1_RS12170 3b8d59801ad6e60a0c1a0776cbd65ced 255 SUPERFAMILY SSF117892 51 184 1.06E-42 T 13-09-2016 IPR001107 Band 7 domain THL1_RS12170 3b8d59801ad6e60a0c1a0776cbd65ced 255 PANTHER PTHR10264 10 242 9.3E-109 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS12170 3b8d59801ad6e60a0c1a0776cbd65ced 255 Pfam PF01145 SPFH domain / Band 7 family 25 193 3.5E-34 T 13-09-2016 IPR001107 Band 7 domain THL1_RS12170 3b8d59801ad6e60a0c1a0776cbd65ced 255 PRINTS PR00721 Stomatin signature 153 171 4.1E-62 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS12170 3b8d59801ad6e60a0c1a0776cbd65ced 255 PRINTS PR00721 Stomatin signature 197 220 4.1E-62 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS12170 3b8d59801ad6e60a0c1a0776cbd65ced 255 PRINTS PR00721 Stomatin signature 129 152 4.1E-62 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS12170 3b8d59801ad6e60a0c1a0776cbd65ced 255 PRINTS PR00721 Stomatin signature 27 49 4.1E-62 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS12170 3b8d59801ad6e60a0c1a0776cbd65ced 255 PRINTS PR00721 Stomatin signature 74 95 4.1E-62 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS12170 3b8d59801ad6e60a0c1a0776cbd65ced 255 PRINTS PR00721 Stomatin signature 109 126 4.1E-62 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS12170 3b8d59801ad6e60a0c1a0776cbd65ced 255 PRINTS PR00721 Stomatin signature 172 193 4.1E-62 T 13-09-2016 IPR001972 Stomatin family GO:0016020 THL1_RS12170 3b8d59801ad6e60a0c1a0776cbd65ced 255 SMART SM00244 20 177 7.5E-63 T 13-09-2016 IPR001107 Band 7 domain THL1_RS21670 7cbf02bbcfce46f0a4d2c8019290a69a 500 Gene3D G3DSA:3.40.605.10 27 285 4.2E-101 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS21670 7cbf02bbcfce46f0a4d2c8019290a69a 500 PANTHER PTHR11699 27 500 2.1E-233 T 13-09-2016 THL1_RS21670 7cbf02bbcfce46f0a4d2c8019290a69a 500 Pfam PF00171 Aldehyde dehydrogenase family 34 495 3.2E-176 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS21670 7cbf02bbcfce46f0a4d2c8019290a69a 500 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 271 278 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS21670 7cbf02bbcfce46f0a4d2c8019290a69a 500 Gene3D G3DSA:3.40.309.10 286 470 5.7E-70 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS21670 7cbf02bbcfce46f0a4d2c8019290a69a 500 SUPERFAMILY SSF53720 24 498 1.18E-169 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS24845 cf68519babd33aa7e1fd2b2e121bafb9 178 PANTHER PTHR26402 3 113 4.1E-28 T 13-09-2016 THL1_RS24845 cf68519babd33aa7e1fd2b2e121bafb9 178 SUPERFAMILY SSF52172 3 128 2.7E-30 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS24845 cf68519babd33aa7e1fd2b2e121bafb9 178 Gene3D G3DSA:3.40.50.2300 3 126 1.5E-27 T 13-09-2016 THL1_RS24845 cf68519babd33aa7e1fd2b2e121bafb9 178 SMART SM00448 3 113 3.8E-25 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS24845 cf68519babd33aa7e1fd2b2e121bafb9 178 Pfam PF00072 Response regulator receiver domain 5 111 1.2E-21 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS12595 f32abc3e6f4f34f5c9d71860d5352da0 282 SMART SM00882 4 224 2.6E-38 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS12595 f32abc3e6f4f34f5c9d71860d5352da0 282 SUPERFAMILY SSF100950 4 278 2.15E-79 T 13-09-2016 THL1_RS12595 f32abc3e6f4f34f5c9d71860d5352da0 282 Gene3D G3DSA:3.40.1080.10 4 120 3.3E-85 T 13-09-2016 THL1_RS12595 f32abc3e6f4f34f5c9d71860d5352da0 282 Gene3D G3DSA:3.40.1080.10 158 280 3.3E-85 T 13-09-2016 THL1_RS12595 f32abc3e6f4f34f5c9d71860d5352da0 282 PANTHER PTHR13707 1 265 5.5E-137 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS12595 f32abc3e6f4f34f5c9d71860d5352da0 282 Pfam PF01144 Coenzyme A transferase 6 215 3.3E-23 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS12595 f32abc3e6f4f34f5c9d71860d5352da0 282 PANTHER PTHR13707:SF33 1 265 5.5E-137 T 13-09-2016 THL1_RS06250 5d286284778c17d187a914368edc6fd9 276 PANTHER PTHR24322 145 176 2.6E-50 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06250 5d286284778c17d187a914368edc6fd9 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 3.6E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06250 5d286284778c17d187a914368edc6fd9 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 3.6E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06250 5d286284778c17d187a914368edc6fd9 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 3.6E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06250 5d286284778c17d187a914368edc6fd9 276 PANTHER PTHR24322 8 129 2.6E-50 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06250 5d286284778c17d187a914368edc6fd9 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 3.0E-27 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06250 5d286284778c17d187a914368edc6fd9 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 3.0E-27 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06250 5d286284778c17d187a914368edc6fd9 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 3.0E-27 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06250 5d286284778c17d187a914368edc6fd9 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 3.0E-27 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06250 5d286284778c17d187a914368edc6fd9 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 3.0E-27 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06250 5d286284778c17d187a914368edc6fd9 276 PANTHER PTHR24322:SF513 8 129 2.6E-50 T 13-09-2016 THL1_RS06250 5d286284778c17d187a914368edc6fd9 276 PANTHER PTHR24322:SF513 145 176 2.6E-50 T 13-09-2016 THL1_RS06250 5d286284778c17d187a914368edc6fd9 276 Gene3D G3DSA:3.40.50.720 5 268 2.8E-64 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS06250 5d286284778c17d187a914368edc6fd9 276 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS06250 5d286284778c17d187a914368edc6fd9 276 Pfam PF00106 short chain dehydrogenase 5 187 7.0E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06250 5d286284778c17d187a914368edc6fd9 276 SUPERFAMILY SSF51735 5 236 6.2E-59 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20855 a4cdf92ec13273da1ca6523756b92e32 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 342 361 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS20855 a4cdf92ec13273da1ca6523756b92e32 383 Gene3D G3DSA:2.40.110.10 127 222 5.1E-38 T 13-09-2016 THL1_RS20855 a4cdf92ec13273da1ca6523756b92e32 383 Gene3D G3DSA:1.20.140.10 223 383 1.4E-50 T 13-09-2016 THL1_RS20855 a4cdf92ec13273da1ca6523756b92e32 383 SUPERFAMILY SSF47203 234 383 8.7E-42 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS20855 a4cdf92ec13273da1ca6523756b92e32 383 SUPERFAMILY SSF56645 8 246 3.27E-77 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS20855 a4cdf92ec13273da1ca6523756b92e32 383 PANTHER PTHR10909 8 383 6.0E-144 T 13-09-2016 THL1_RS20855 a4cdf92ec13273da1ca6523756b92e32 383 PANTHER PTHR10909:SF190 8 383 6.0E-144 T 13-09-2016 THL1_RS20855 a4cdf92ec13273da1ca6523756b92e32 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 123 7.8E-26 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS20855 a4cdf92ec13273da1ca6523756b92e32 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 222 1.7E-26 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS20855 a4cdf92ec13273da1ca6523756b92e32 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 383 6.5E-39 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS20855 a4cdf92ec13273da1ca6523756b92e32 383 Gene3D G3DSA:1.10.540.10 10 124 1.1E-31 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS00465 5cf914a510d6e9653d4354c77e185066 435 PANTHER PTHR10283:SF87 1 21 9.7E-197 T 13-09-2016 IPR014738 Citrate transporter GO:0015137|GO:0015746 THL1_RS00465 5cf914a510d6e9653d4354c77e185066 435 PANTHER PTHR10283:SF87 49 429 9.7E-197 T 13-09-2016 IPR014738 Citrate transporter GO:0015137|GO:0015746 THL1_RS00465 5cf914a510d6e9653d4354c77e185066 435 TIGRFAM TIGR00784 citMHS: citrate transporter 1 429 7.2E-190 T 13-09-2016 IPR014738 Citrate transporter GO:0015137|GO:0015746 THL1_RS00465 5cf914a510d6e9653d4354c77e185066 435 PANTHER PTHR10283 49 429 9.7E-197 T 13-09-2016 THL1_RS00465 5cf914a510d6e9653d4354c77e185066 435 Pfam PF03600 Citrate transporter 13 377 1.5E-52 T 13-09-2016 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 THL1_RS00465 5cf914a510d6e9653d4354c77e185066 435 PANTHER PTHR10283 1 21 9.7E-197 T 13-09-2016 THL1_RS22995 ae179cd978a34003f22f3bccebcd7a27 367 Pfam PF01594 Domain of unknown function DUF20 24 346 8.0E-29 T 13-09-2016 IPR002549 Transmembrane protein TqsA-like THL1_RS22995 ae179cd978a34003f22f3bccebcd7a27 367 PANTHER PTHR21716 17 365 4.1E-68 T 13-09-2016 IPR002549 Transmembrane protein TqsA-like THL1_RS22995 ae179cd978a34003f22f3bccebcd7a27 367 PANTHER PTHR21716:SF20 17 365 4.1E-68 T 13-09-2016 THL1_RS14350 68827ceff2256b3f836473175af6a336 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 2.0E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14350 68827ceff2256b3f836473175af6a336 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 2.0E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14350 68827ceff2256b3f836473175af6a336 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 2.0E-7 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14350 68827ceff2256b3f836473175af6a336 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 1.4E-19 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS14350 68827ceff2256b3f836473175af6a336 309 PANTHER PTHR30346:SF11 7 300 1.1E-147 T 13-09-2016 THL1_RS14350 68827ceff2256b3f836473175af6a336 309 Gene3D G3DSA:1.10.10.10 6 86 1.8E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14350 68827ceff2256b3f836473175af6a336 309 TIGRFAM TIGR02424 TF_pcaQ: pca operon transcription factor PcaQ 5 300 2.0E-114 T 13-09-2016 IPR012787 Pca transcription factor PcaQ GO:0003677|GO:0019619|GO:0045893 THL1_RS14350 68827ceff2256b3f836473175af6a336 309 Pfam PF03466 LysR substrate binding domain 94 300 1.2E-34 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS14350 68827ceff2256b3f836473175af6a336 309 Gene3D G3DSA:3.40.190.10 95 186 2.8E-19 T 13-09-2016 THL1_RS14350 68827ceff2256b3f836473175af6a336 309 SUPERFAMILY SSF46785 5 115 1.12E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14350 68827ceff2256b3f836473175af6a336 309 PANTHER PTHR30346 7 300 1.1E-147 T 13-09-2016 THL1_RS14350 68827ceff2256b3f836473175af6a336 309 Gene3D G3DSA:3.40.190.10 187 266 6.5E-10 T 13-09-2016 THL1_RS14350 68827ceff2256b3f836473175af6a336 309 SUPERFAMILY SSF53850 95 301 1.09E-34 T 13-09-2016 THL1_RS09015 95e1f8f3c2d4de1ad2b9cde1d86c9de1 223 Gene3D G3DSA:2.40.170.20 158 221 1.0E-11 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS09015 95e1f8f3c2d4de1ad2b9cde1d86c9de1 223 Pfam PF07715 TonB-dependent Receptor Plug Domain 46 151 7.5E-29 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS09015 95e1f8f3c2d4de1ad2b9cde1d86c9de1 223 SUPERFAMILY SSF56935 166 220 2.47E-8 T 13-09-2016 THL1_RS09015 95e1f8f3c2d4de1ad2b9cde1d86c9de1 223 Pfam PF00593 TonB dependent receptor 160 221 3.0E-6 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS09015 95e1f8f3c2d4de1ad2b9cde1d86c9de1 223 PANTHER PTHR30069:SF2 30 209 1.8E-44 T 13-09-2016 THL1_RS09015 95e1f8f3c2d4de1ad2b9cde1d86c9de1 223 PANTHER PTHR30069 30 209 1.8E-44 T 13-09-2016 THL1_RS09015 95e1f8f3c2d4de1ad2b9cde1d86c9de1 223 Gene3D G3DSA:2.170.130.10 24 157 5.1E-40 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS09015 95e1f8f3c2d4de1ad2b9cde1d86c9de1 223 SUPERFAMILY SSF56935 24 169 1.37E-41 T 13-09-2016 THL1_RS06305 9e5a54e618bd1ac093d5ef502f60021b 386 Pfam PF13437 HlyD family secretion protein 260 332 9.5E-8 T 13-09-2016 THL1_RS06305 9e5a54e618bd1ac093d5ef502f60021b 386 SUPERFAMILY SSF141371 10 129 3.14E-12 T 13-09-2016 THL1_RS06305 9e5a54e618bd1ac093d5ef502f60021b 386 Gene3D G3DSA:2.40.50.100 199 289 5.9E-5 T 13-09-2016 THL1_RS06305 9e5a54e618bd1ac093d5ef502f60021b 386 Pfam PF07238 PilZ domain 16 114 7.6E-11 T 13-09-2016 IPR009875 PilZ domain GO:0035438 THL1_RS06305 9e5a54e618bd1ac093d5ef502f60021b 386 Gene3D G3DSA:2.40.10.220 13 125 1.2E-6 T 13-09-2016 THL1_RS10765 19a12a156bd330b98fda76af2b7adc2c 175 PANTHER PTHR40547 1 175 3.9E-51 T 13-09-2016 THL1_RS10765 19a12a156bd330b98fda76af2b7adc2c 175 PANTHER PTHR40547:SF1 1 175 3.9E-51 T 13-09-2016 THL1_RS10765 19a12a156bd330b98fda76af2b7adc2c 175 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 22 164 4.2E-49 T 13-09-2016 IPR018639 Domain of unknown function DUF2062 THL1_RS24210 524dad7ca95801db4c78be9df1950e8d 254 Gene3D G3DSA:1.25.40.10 156 243 8.6E-10 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS24210 524dad7ca95801db4c78be9df1950e8d 254 SUPERFAMILY SSF48452 153 250 9.17E-10 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS24920 494746eae497968a34ce40e0ccce15ba 429 SUPERFAMILY SSF51905 28 253 2.69E-42 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS24920 494746eae497968a34ce40e0ccce15ba 429 SUPERFAMILY SSF51905 344 400 2.69E-42 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS24920 494746eae497968a34ce40e0ccce15ba 429 PANTHER PTHR13847:SF196 9 383 2.0E-83 T 13-09-2016 THL1_RS24920 494746eae497968a34ce40e0ccce15ba 429 Pfam PF01266 FAD dependent oxidoreductase 29 380 7.3E-50 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS24920 494746eae497968a34ce40e0ccce15ba 429 Gene3D G3DSA:3.50.50.60 172 252 3.2E-47 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS24920 494746eae497968a34ce40e0ccce15ba 429 Gene3D G3DSA:3.50.50.60 344 386 3.2E-47 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS24920 494746eae497968a34ce40e0ccce15ba 429 Gene3D G3DSA:3.50.50.60 17 119 3.2E-47 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS24920 494746eae497968a34ce40e0ccce15ba 429 PANTHER PTHR13847 9 383 2.0E-83 T 13-09-2016 THL1_RS23065 a893d1926ebb10a73bcfedafc895a195 142 Pfam PF03061 Thioesterase superfamily 31 104 1.5E-16 T 13-09-2016 IPR006683 Thioesterase domain THL1_RS23065 a893d1926ebb10a73bcfedafc895a195 142 SUPERFAMILY SSF54637 16 136 5.29E-35 T 13-09-2016 IPR029069 HotDog domain THL1_RS23065 a893d1926ebb10a73bcfedafc895a195 142 Gene3D G3DSA:3.10.129.10 5 128 4.7E-43 T 13-09-2016 IPR029069 HotDog domain THL1_RS23065 a893d1926ebb10a73bcfedafc895a195 142 PANTHER PTHR11049 3 141 1.8E-79 T 13-09-2016 THL1_RS23065 a893d1926ebb10a73bcfedafc895a195 142 PANTHER PTHR11049:SF8 3 141 1.8E-79 T 13-09-2016 THL1_RS00455 59d4e6e7b0438e731fb15976ccdd329c 612 Gene3D G3DSA:3.40.50.300 509 580 5.4E-11 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00455 59d4e6e7b0438e731fb15976ccdd329c 612 Gene3D G3DSA:3.40.50.300 107 370 8.7E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00455 59d4e6e7b0438e731fb15976ccdd329c 612 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 7 588 53.037 T 13-09-2016 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 THL1_RS00455 59d4e6e7b0438e731fb15976ccdd329c 612 SMART SM00382 158 380 0.0031 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS00455 59d4e6e7b0438e731fb15976ccdd329c 612 Pfam PF13538 UvrD-like helicase C-terminal domain 517 561 4.6E-13 T 13-09-2016 IPR027785 UvrD-like helicase C-terminal domain THL1_RS00455 59d4e6e7b0438e731fb15976ccdd329c 612 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 8 588 3.5E-171 T 13-09-2016 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 THL1_RS00455 59d4e6e7b0438e731fb15976ccdd329c 612 PANTHER PTHR10887 147 325 3.1E-62 T 13-09-2016 THL1_RS00455 59d4e6e7b0438e731fb15976ccdd329c 612 Pfam PF13604 AAA domain 149 326 1.7E-31 T 13-09-2016 THL1_RS00455 59d4e6e7b0438e731fb15976ccdd329c 612 SUPERFAMILY SSF52540 22 314 1.02E-40 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00455 59d4e6e7b0438e731fb15976ccdd329c 612 SUPERFAMILY SSF52540 276 369 5.49E-54 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00455 59d4e6e7b0438e731fb15976ccdd329c 612 SUPERFAMILY SSF52540 421 588 5.49E-54 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00455 59d4e6e7b0438e731fb15976ccdd329c 612 PANTHER PTHR10887:SF351 147 325 3.1E-62 T 13-09-2016 THL1_RS08195 3583ef19bffbd1b4adc8871d473c52bc 215 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 185 198 - T 13-09-2016 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 THL1_RS08195 3583ef19bffbd1b4adc8871d473c52bc 215 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 11 215 38.574 T 13-09-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 THL1_RS08195 3583ef19bffbd1b4adc8871d473c52bc 215 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 42 122 1.0E-26 T 13-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 THL1_RS08195 3583ef19bffbd1b4adc8871d473c52bc 215 Gene3D G3DSA:2.30.110.10 17 215 1.4E-82 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS08195 3583ef19bffbd1b4adc8871d473c52bc 215 SUPERFAMILY SSF50475 8 215 3.42E-65 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS08195 3583ef19bffbd1b4adc8871d473c52bc 215 PANTHER PTHR10851:SF0 1 215 2.1E-110 T 13-09-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 THL1_RS08195 3583ef19bffbd1b4adc8871d473c52bc 215 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 3 215 2.8E-87 T 13-09-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 THL1_RS08195 3583ef19bffbd1b4adc8871d473c52bc 215 PIRSF PIRSF000190 1 215 5.8E-80 T 13-09-2016 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 THL1_RS08195 3583ef19bffbd1b4adc8871d473c52bc 215 PANTHER PTHR10851 1 215 2.1E-110 T 13-09-2016 THL1_RS08195 3583ef19bffbd1b4adc8871d473c52bc 215 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 175 215 1.1E-18 T 13-09-2016 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 THL1_RS21535 5257eb24287286148beba53ad542011c 284 Pfam PF16106 Domain of unknown function (DUF4824) 17 257 6.7E-82 T 13-09-2016 IPR032249 Protein of unknown function DUF4824 THL1_RS20870 ffa119d436041141be0af77b7a1fba9f 209 SUPERFAMILY SSF46689 15 80 1.64E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS20870 ffa119d436041141be0af77b7a1fba9f 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 3.3E-9 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20870 ffa119d436041141be0af77b7a1fba9f 209 SUPERFAMILY SSF48498 89 194 7.63E-7 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS20870 ffa119d436041141be0af77b7a1fba9f 209 PANTHER PTHR30055 3 184 3.8E-21 T 13-09-2016 THL1_RS20870 ffa119d436041141be0af77b7a1fba9f 209 Gene3D G3DSA:1.10.357.10 7 207 8.3E-40 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS22145 2a452ec35420cdc48810004cced1459e 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.0E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22145 2a452ec35420cdc48810004cced1459e 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.0E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22145 2a452ec35420cdc48810004cced1459e 272 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.0E-10 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22145 2a452ec35420cdc48810004cced1459e 272 SUPERFAMILY SSF51735 1 268 3.06E-70 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS22145 2a452ec35420cdc48810004cced1459e 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.3E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22145 2a452ec35420cdc48810004cced1459e 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.3E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22145 2a452ec35420cdc48810004cced1459e 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.3E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22145 2a452ec35420cdc48810004cced1459e 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.3E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22145 2a452ec35420cdc48810004cced1459e 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.3E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22145 2a452ec35420cdc48810004cced1459e 272 PANTHER PTHR24322:SF365 11 139 9.3E-65 T 13-09-2016 THL1_RS22145 2a452ec35420cdc48810004cced1459e 272 PANTHER PTHR24322:SF365 155 187 9.3E-65 T 13-09-2016 THL1_RS22145 2a452ec35420cdc48810004cced1459e 272 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 191 5.3E-5 T 13-09-2016 THL1_RS22145 2a452ec35420cdc48810004cced1459e 272 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS22145 2a452ec35420cdc48810004cced1459e 272 PANTHER PTHR24322 11 139 9.3E-65 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22145 2a452ec35420cdc48810004cced1459e 272 PANTHER PTHR24322 155 187 9.3E-65 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22145 2a452ec35420cdc48810004cced1459e 272 Gene3D G3DSA:3.40.50.720 5 244 7.4E-71 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS22145 2a452ec35420cdc48810004cced1459e 272 Pfam PF00106 short chain dehydrogenase 7 196 3.6E-53 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS00125 5a43ffbb099d6e71436bbbd81c41b7c9 325 SUPERFAMILY SSF51735 112 265 4.2E-46 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS00125 5a43ffbb099d6e71436bbbd81c41b7c9 325 PANTHER PTHR11695:SF605 16 325 1.3E-134 T 13-09-2016 THL1_RS00125 5a43ffbb099d6e71436bbbd81c41b7c9 325 SMART SM00829 11 323 3.5E-37 T 13-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THL1_RS00125 5a43ffbb099d6e71436bbbd81c41b7c9 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 3.4E-9 T 13-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THL1_RS00125 5a43ffbb099d6e71436bbbd81c41b7c9 325 Gene3D G3DSA:3.90.180.10 3 144 1.6E-50 T 13-09-2016 IPR011032 GroES-like THL1_RS00125 5a43ffbb099d6e71436bbbd81c41b7c9 325 Pfam PF00107 Zinc-binding dehydrogenase 152 258 3.3E-26 T 13-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THL1_RS00125 5a43ffbb099d6e71436bbbd81c41b7c9 325 SUPERFAMILY SSF50129 9 142 1.89E-39 T 13-09-2016 IPR011032 GroES-like THL1_RS00125 5a43ffbb099d6e71436bbbd81c41b7c9 325 Gene3D G3DSA:3.40.50.720 145 256 3.7E-29 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS00125 5a43ffbb099d6e71436bbbd81c41b7c9 325 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 13-09-2016 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 THL1_RS00125 5a43ffbb099d6e71436bbbd81c41b7c9 325 PANTHER PTHR11695 16 325 1.3E-134 T 13-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 THL1_RS20740 ac7f5d69f1767bb630d7b0a5e5cca580 326 Pfam PF11740 Plasmid replication region DNA-binding N-term 9 114 4.2E-18 T 13-09-2016 IPR021104 KfrA, N-terminal DNA-binding domain THL1_RS08640 23125888428c8d4642a74f3ef84e70a1 269 PANTHER PTHR10992 3 259 2.3E-70 T 13-09-2016 THL1_RS08640 23125888428c8d4642a74f3ef84e70a1 269 PANTHER PTHR10992:SF771 3 259 2.3E-70 T 13-09-2016 THL1_RS08640 23125888428c8d4642a74f3ef84e70a1 269 SUPERFAMILY SSF53474 1 258 3.41E-73 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS08640 23125888428c8d4642a74f3ef84e70a1 269 Pfam PF00561 alpha/beta hydrolase fold 21 132 2.8E-26 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS08640 23125888428c8d4642a74f3ef84e70a1 269 Gene3D G3DSA:3.40.50.1820 1 261 8.5E-73 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS08640 23125888428c8d4642a74f3ef84e70a1 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 102 5.9E-8 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS08640 23125888428c8d4642a74f3ef84e70a1 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 5.9E-8 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS08640 23125888428c8d4642a74f3ef84e70a1 269 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 5.9E-8 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS22955 846613be2813ff1f51752fdf315d30b1 383 PANTHER PTHR30222 1 328 6.7E-71 T 13-09-2016 THL1_RS22955 846613be2813ff1f51752fdf315d30b1 383 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 138 154 2.3E-8 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS22955 846613be2813ff1f51752fdf315d30b1 383 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 163 177 2.3E-8 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS22955 846613be2813ff1f51752fdf315d30b1 383 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 278 297 2.3E-8 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS22955 846613be2813ff1f51752fdf315d30b1 383 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 64 85 2.3E-8 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS22955 846613be2813ff1f51752fdf315d30b1 383 Pfam PF13416 Bacterial extracellular solute-binding protein 58 328 1.8E-27 T 13-09-2016 THL1_RS22955 846613be2813ff1f51752fdf315d30b1 383 SUPERFAMILY SSF53850 35 360 5.18E-57 T 13-09-2016 THL1_RS22955 846613be2813ff1f51752fdf315d30b1 383 Gene3D G3DSA:3.40.190.10 149 301 2.5E-29 T 13-09-2016 THL1_RS22955 846613be2813ff1f51752fdf315d30b1 383 Gene3D G3DSA:3.40.190.10 302 329 4.1E-29 T 13-09-2016 THL1_RS22955 846613be2813ff1f51752fdf315d30b1 383 Gene3D G3DSA:3.40.190.10 35 147 4.1E-29 T 13-09-2016 THL1_RS22955 846613be2813ff1f51752fdf315d30b1 383 PANTHER PTHR30222:SF5 1 328 6.7E-71 T 13-09-2016 THL1_RS18025 9f3aa0fd5344e52c1419d0aba4bd2ffc 284 SUPERFAMILY SSF51735 123 281 1.25E-51 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18025 9f3aa0fd5344e52c1419d0aba4bd2ffc 284 Gene3D G3DSA:3.40.50.720 141 264 7.9E-50 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18025 9f3aa0fd5344e52c1419d0aba4bd2ffc 284 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 38.315 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS18025 9f3aa0fd5344e52c1419d0aba4bd2ffc 284 PANTHER PTHR10025 1 280 2.5E-174 T 13-09-2016 THL1_RS18025 9f3aa0fd5344e52c1419d0aba4bd2ffc 284 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 281 7.0E-67 T 13-09-2016 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS18025 9f3aa0fd5344e52c1419d0aba4bd2ffc 284 Gene3D G3DSA:3.40.192.10 7 140 1.3E-52 T 13-09-2016 THL1_RS18025 9f3aa0fd5344e52c1419d0aba4bd2ffc 284 SUPERFAMILY SSF53223 1 122 2.3E-41 T 13-09-2016 THL1_RS18025 9f3aa0fd5344e52c1419d0aba4bd2ffc 284 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 121 7.8E-41 T 13-09-2016 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS18025 9f3aa0fd5344e52c1419d0aba4bd2ffc 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 110 131 2.2E-85 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS18025 9f3aa0fd5344e52c1419d0aba4bd2ffc 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 2.2E-85 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS18025 9f3aa0fd5344e52c1419d0aba4bd2ffc 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 204 233 2.2E-85 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS18025 9f3aa0fd5344e52c1419d0aba4bd2ffc 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 75 102 2.2E-85 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS18025 9f3aa0fd5344e52c1419d0aba4bd2ffc 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 34 56 2.2E-85 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS18025 9f3aa0fd5344e52c1419d0aba4bd2ffc 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 155 175 2.2E-85 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS18025 9f3aa0fd5344e52c1419d0aba4bd2ffc 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 239 255 2.2E-85 T 13-09-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS18025 9f3aa0fd5344e52c1419d0aba4bd2ffc 284 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 76 101 - T 13-09-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 THL1_RS21025 0177f5654fe67000e397ce02ffec30c2 254 Gene3D G3DSA:3.40.50.720 2 210 4.2E-52 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS21025 0177f5654fe67000e397ce02ffec30c2 254 PANTHER PTHR24322 8 132 3.2E-35 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21025 0177f5654fe67000e397ce02ffec30c2 254 PANTHER PTHR24322 148 184 3.2E-35 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21025 0177f5654fe67000e397ce02ffec30c2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 8.5E-18 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21025 0177f5654fe67000e397ce02ffec30c2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 8.5E-18 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21025 0177f5654fe67000e397ce02ffec30c2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 8.5E-18 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21025 0177f5654fe67000e397ce02ffec30c2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 8.5E-18 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21025 0177f5654fe67000e397ce02ffec30c2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 8.5E-18 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS21025 0177f5654fe67000e397ce02ffec30c2 254 SUPERFAMILY SSF51735 2 249 1.94E-56 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS21025 0177f5654fe67000e397ce02ffec30c2 254 Pfam PF00106 short chain dehydrogenase 5 191 2.4E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16730 059fe3d571e394e6c7438cad63058d12 276 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 264 17.6 T 13-09-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 THL1_RS16730 059fe3d571e394e6c7438cad63058d12 276 PANTHER PTHR30622:SF3 2 272 1.2E-134 T 13-09-2016 THL1_RS16730 059fe3d571e394e6c7438cad63058d12 276 Pfam PF02673 Bacitracin resistance protein BacA 10 258 4.2E-78 T 13-09-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 THL1_RS16730 059fe3d571e394e6c7438cad63058d12 276 PANTHER PTHR30622 2 272 1.2E-134 T 13-09-2016 THL1_RS16730 059fe3d571e394e6c7438cad63058d12 276 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 256 5.1E-78 T 13-09-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 THL1_RS21770 24b7aebee36b3ed0b3f6c454f9a0541b 220 Pfam PF06035 Bacterial transglutaminase-like cysteine proteinase BTLCP 64 170 2.1E-18 T 13-09-2016 IPR010319 Transglutaminase-like cysteine peptidase, predicted THL1_RS21770 24b7aebee36b3ed0b3f6c454f9a0541b 220 SUPERFAMILY SSF54001 46 124 5.23E-6 T 13-09-2016 THL1_RS21770 24b7aebee36b3ed0b3f6c454f9a0541b 220 PANTHER PTHR39327 14 216 1.7E-65 T 13-09-2016 THL1_RS21770 24b7aebee36b3ed0b3f6c454f9a0541b 220 PANTHER PTHR39327:SF1 14 216 1.7E-65 T 13-09-2016 THL1_RS19750 a7fa10c5d671101d43edcfa8577f5bea 144 Pfam PF02082 Transcriptional regulator 1 82 7.8E-19 T 13-09-2016 IPR000944 Transcription regulator Rrf2-type THL1_RS19750 a7fa10c5d671101d43edcfa8577f5bea 144 Gene3D G3DSA:1.10.10.10 1 135 6.5E-28 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19750 a7fa10c5d671101d43edcfa8577f5bea 144 PANTHER PTHR33221 2 133 9.6E-21 T 13-09-2016 THL1_RS19750 a7fa10c5d671101d43edcfa8577f5bea 144 PANTHER PTHR33221:SF5 2 133 9.6E-21 T 13-09-2016 THL1_RS19750 a7fa10c5d671101d43edcfa8577f5bea 144 SUPERFAMILY SSF46785 5 132 1.52E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20245 18f2fd1ad606c2da928ebc4865f28c8e 284 SUPERFAMILY SSF111369 42 207 4.18E-22 T 13-09-2016 THL1_RS20245 18f2fd1ad606c2da928ebc4865f28c8e 284 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 42 235 1.7E-37 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS20245 18f2fd1ad606c2da928ebc4865f28c8e 284 PANTHER PTHR30367 1 282 3.8E-124 T 13-09-2016 THL1_RS20245 18f2fd1ad606c2da928ebc4865f28c8e 284 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 42 227 4.3E-17 T 13-09-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THL1_RS20245 18f2fd1ad606c2da928ebc4865f28c8e 284 Gene3D G3DSA:2.40.50.100 43 76 8.8E-19 T 13-09-2016 THL1_RS20245 18f2fd1ad606c2da928ebc4865f28c8e 284 Gene3D G3DSA:2.40.50.100 150 183 8.8E-19 T 13-09-2016 THL1_RS20245 18f2fd1ad606c2da928ebc4865f28c8e 284 PANTHER PTHR30367:SF3 1 282 3.8E-124 T 13-09-2016 THL1_RS20245 18f2fd1ad606c2da928ebc4865f28c8e 284 Pfam PF00529 HlyD membrane-fusion protein of T1SS 23 283 1.1E-6 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS02350 a356e5a0cb74ca48da67678f1634159f 362 SUPERFAMILY SSF50331 244 360 2.27E-12 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS02350 a356e5a0cb74ca48da67678f1634159f 362 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS02350 a356e5a0cb74ca48da67678f1634159f 362 PANTHER PTHR24220 8 253 3.1E-140 T 13-09-2016 THL1_RS02350 a356e5a0cb74ca48da67678f1634159f 362 Gene3D G3DSA:3.40.50.300 3 244 2.2E-82 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS02350 a356e5a0cb74ca48da67678f1634159f 362 Pfam PF00005 ABC transporter 26 168 3.9E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS02350 a356e5a0cb74ca48da67678f1634159f 362 Pfam PF08402 TOBE domain 285 359 9.2E-12 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS02350 a356e5a0cb74ca48da67678f1634159f 362 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 41 353 1.6E-113 T 13-09-2016 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 THL1_RS02350 a356e5a0cb74ca48da67678f1634159f 362 SUPERFAMILY SSF52540 7 248 4.37E-88 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS02350 a356e5a0cb74ca48da67678f1634159f 362 PANTHER PTHR24220:SF150 8 253 3.1E-140 T 13-09-2016 THL1_RS02350 a356e5a0cb74ca48da67678f1634159f 362 SMART SM00382 35 226 1.0E-20 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS01020 bfe4d1cd2d9103f72dfc9951fd169566 264 ProSitePatterns PS00091 Thymidylate synthase active site. 126 154 - T 13-09-2016 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 THL1_RS01020 bfe4d1cd2d9103f72dfc9951fd169566 264 PANTHER PTHR11548 1 264 6.4E-195 T 13-09-2016 THL1_RS01020 bfe4d1cd2d9103f72dfc9951fd169566 264 Hamap MF_00008 Thymidylate synthase [thyA]. 1 264 46.505 T 13-09-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 THL1_RS01020 bfe4d1cd2d9103f72dfc9951fd169566 264 SUPERFAMILY SSF55831 1 264 2.62E-130 T 13-09-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 THL1_RS01020 bfe4d1cd2d9103f72dfc9951fd169566 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 85 2.2E-41 T 13-09-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 THL1_RS01020 bfe4d1cd2d9103f72dfc9951fd169566 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 84 264 5.0E-97 T 13-09-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 THL1_RS01020 bfe4d1cd2d9103f72dfc9951fd169566 264 PRINTS PR00108 Thymidylate synthase family signature 115 134 6.7E-48 T 13-09-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 THL1_RS01020 bfe4d1cd2d9103f72dfc9951fd169566 264 PRINTS PR00108 Thymidylate synthase family signature 197 214 6.7E-48 T 13-09-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 THL1_RS01020 bfe4d1cd2d9103f72dfc9951fd169566 264 PRINTS PR00108 Thymidylate synthase family signature 141 156 6.7E-48 T 13-09-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 THL1_RS01020 bfe4d1cd2d9103f72dfc9951fd169566 264 PRINTS PR00108 Thymidylate synthase family signature 42 63 6.7E-48 T 13-09-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 THL1_RS01020 bfe4d1cd2d9103f72dfc9951fd169566 264 PRINTS PR00108 Thymidylate synthase family signature 159 185 6.7E-48 T 13-09-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 THL1_RS01020 bfe4d1cd2d9103f72dfc9951fd169566 264 Pfam PF00303 Thymidylate synthase 2 264 1.9E-123 T 13-09-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 THL1_RS01020 bfe4d1cd2d9103f72dfc9951fd169566 264 Gene3D G3DSA:3.30.572.10 1 264 9.5E-135 T 13-09-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 THL1_RS28500 3ec98a8b2f29f7d7ff79c302f52d704f 44 PANTHER PTHR14503 1 44 3.5E-23 T 13-09-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS28500 3ec98a8b2f29f7d7ff79c302f52d704f 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 13-09-2016 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS28500 3ec98a8b2f29f7d7ff79c302f52d704f 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.504 T 13-09-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS28500 3ec98a8b2f29f7d7ff79c302f52d704f 44 Pfam PF00468 Ribosomal protein L34 1 44 1.6E-25 T 13-09-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS28500 3ec98a8b2f29f7d7ff79c302f52d704f 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 1.7E-26 T 13-09-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS28500 3ec98a8b2f29f7d7ff79c302f52d704f 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 40 8.0E-15 T 13-09-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS08175 8837fd1b19d4ecf379e8f51a591f09e6 714 PANTHER PTHR11472 1 712 0.0 T 13-09-2016 THL1_RS08175 8837fd1b19d4ecf379e8f51a591f09e6 714 PANTHER PTHR11472:SF32 1 712 0.0 T 13-09-2016 THL1_RS08175 8837fd1b19d4ecf379e8f51a591f09e6 714 Pfam PF13307 Helicase C-terminal domain 553 708 3.4E-32 T 13-09-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 THL1_RS08175 8837fd1b19d4ecf379e8f51a591f09e6 714 SUPERFAMILY SSF52540 516 689 5.04E-16 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08175 8837fd1b19d4ecf379e8f51a591f09e6 714 SUPERFAMILY SSF52540 208 286 5.04E-16 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08175 8837fd1b19d4ecf379e8f51a591f09e6 714 SUPERFAMILY SSF52540 475 489 5.04E-16 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08175 8837fd1b19d4ecf379e8f51a591f09e6 714 SUPERFAMILY SSF52540 57 105 5.04E-16 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08175 8837fd1b19d4ecf379e8f51a591f09e6 714 Gene3D G3DSA:3.40.50.300 540 690 3.3E-8 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08175 8837fd1b19d4ecf379e8f51a591f09e6 714 Gene3D G3DSA:3.40.50.300 227 274 9.1E-13 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08175 8837fd1b19d4ecf379e8f51a591f09e6 714 Gene3D G3DSA:3.40.50.300 169 170 9.1E-13 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08175 8837fd1b19d4ecf379e8f51a591f09e6 714 Gene3D G3DSA:3.40.50.300 58 130 9.1E-13 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08175 8837fd1b19d4ecf379e8f51a591f09e6 714 SMART SM00491 562 695 2.6E-30 T 13-09-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 THL1_RS09615 8e8ba5f51d3bb026d4cd8137198b4de4 322 PANTHER PTHR35007:SF2 19 320 1.0E-56 T 13-09-2016 THL1_RS09615 8e8ba5f51d3bb026d4cd8137198b4de4 322 PANTHER PTHR35007 19 320 1.0E-56 T 13-09-2016 THL1_RS09615 8e8ba5f51d3bb026d4cd8137198b4de4 322 Pfam PF00482 Type II secretion system (T2SS), protein F 180 307 2.1E-21 T 13-09-2016 IPR018076 Type II secretion system F domain THL1_RS00275 0d89ac949e52bb03d9746d80af8ff248 242 PANTHER PTHR23427 22 115 3.9E-13 T 13-09-2016 THL1_RS00275 0d89ac949e52bb03d9746d80af8ff248 242 Pfam PF02104 SURF1 family 17 216 3.8E-31 T 13-09-2016 IPR002994 Surfeit locus 1/Shy1 GO:0016020 THL1_RS00275 0d89ac949e52bb03d9746d80af8ff248 242 PANTHER PTHR23427:SF2 22 115 3.9E-13 T 13-09-2016 THL1_RS28040 6a4708b4240be5fe9177acb85c3473f9 323 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 3 309 1.6E-98 T 13-09-2016 IPR011862 Phosphate binding protein GO:0006810 THL1_RS28040 6a4708b4240be5fe9177acb85c3473f9 323 Gene3D G3DSA:3.40.190.10 123 266 8.0E-38 T 13-09-2016 THL1_RS28040 6a4708b4240be5fe9177acb85c3473f9 323 PANTHER PTHR30570:SF5 17 321 3.7E-158 T 13-09-2016 THL1_RS28040 6a4708b4240be5fe9177acb85c3473f9 323 Gene3D G3DSA:3.40.190.10 267 319 7.6E-11 T 13-09-2016 THL1_RS28040 6a4708b4240be5fe9177acb85c3473f9 323 Gene3D G3DSA:3.40.190.10 42 120 7.6E-11 T 13-09-2016 THL1_RS28040 6a4708b4240be5fe9177acb85c3473f9 323 SUPERFAMILY SSF53850 37 321 2.59E-74 T 13-09-2016 THL1_RS28040 6a4708b4240be5fe9177acb85c3473f9 323 PANTHER PTHR30570 17 321 3.7E-158 T 13-09-2016 THL1_RS28040 6a4708b4240be5fe9177acb85c3473f9 323 Pfam PF12849 PBP superfamily domain 37 294 8.0E-36 T 13-09-2016 IPR024370 PBP domain THL1_RS24180 5b684fd9bc0fdd41571fd766003e69eb 338 SUPERFAMILY SSF51735 1 182 3.54E-75 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS24180 5b684fd9bc0fdd41571fd766003e69eb 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 326 3.3E-129 T 13-09-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS24180 5b684fd9bc0fdd41571fd766003e69eb 338 Gene3D G3DSA:1.10.1040.10 39 325 2.4E-114 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS24180 5b684fd9bc0fdd41571fd766003e69eb 338 Gene3D G3DSA:3.50.50.60 3 38 1.6E-5 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS24180 5b684fd9bc0fdd41571fd766003e69eb 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 2.0E-63 T 13-09-2016 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS24180 5b684fd9bc0fdd41571fd766003e69eb 338 SUPERFAMILY SSF48179 183 332 1.43E-69 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS24180 5b684fd9bc0fdd41571fd766003e69eb 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 4.4E-75 T 13-09-2016 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS24180 5b684fd9bc0fdd41571fd766003e69eb 338 PANTHER PTHR21371 1 337 1.5E-191 T 13-09-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS24180 5b684fd9bc0fdd41571fd766003e69eb 338 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 1 328 45.051 T 13-09-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS04870 06eda091ee4f44fe371256285e3cadcd 145 PANTHER PTHR10516 132 145 1.2E-19 T 13-09-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type THL1_RS04870 06eda091ee4f44fe371256285e3cadcd 145 PANTHER PTHR10516:SF329 132 145 1.2E-19 T 13-09-2016 THL1_RS04870 06eda091ee4f44fe371256285e3cadcd 145 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 10 140 4.3E-18 T 13-09-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 THL1_RS04870 06eda091ee4f44fe371256285e3cadcd 145 Gene3D G3DSA:3.10.50.40 129 144 1.7E-21 T 13-09-2016 THL1_RS04870 06eda091ee4f44fe371256285e3cadcd 145 Gene3D G3DSA:3.10.50.40 8 83 1.7E-21 T 13-09-2016 THL1_RS04870 06eda091ee4f44fe371256285e3cadcd 145 PANTHER PTHR10516 5 85 1.2E-19 T 13-09-2016 IPR023566 Peptidyl-prolyl cis-trans isomerase, FKBP-type THL1_RS04870 06eda091ee4f44fe371256285e3cadcd 145 SUPERFAMILY SSF54534 8 143 1.32E-37 T 13-09-2016 THL1_RS04870 06eda091ee4f44fe371256285e3cadcd 145 PANTHER PTHR10516:SF329 5 85 1.2E-19 T 13-09-2016 THL1_RS18990 c855a9ae8342b21168113d2187de71e1 307 PANTHER PTHR11732 36 289 5.1E-46 T 13-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta THL1_RS18990 c855a9ae8342b21168113d2187de71e1 307 Pfam PF00248 Aldo/keto reductase family 71 290 1.3E-27 T 13-09-2016 IPR023210 NADP-dependent oxidoreductase domain THL1_RS18990 c855a9ae8342b21168113d2187de71e1 307 Gene3D G3DSA:3.20.20.100 37 291 4.1E-46 T 13-09-2016 IPR023210 NADP-dependent oxidoreductase domain THL1_RS18990 c855a9ae8342b21168113d2187de71e1 307 SUPERFAMILY SSF51430 37 290 5.11E-52 T 13-09-2016 IPR023210 NADP-dependent oxidoreductase domain THL1_RS18990 c855a9ae8342b21168113d2187de71e1 307 PRINTS PR00069 Aldo-keto reductase signature 161 178 8.1E-5 T 13-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 THL1_RS18990 c855a9ae8342b21168113d2187de71e1 307 PRINTS PR00069 Aldo-keto reductase signature 79 103 8.1E-5 T 13-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 THL1_RS18990 c855a9ae8342b21168113d2187de71e1 307 PRINTS PR00069 Aldo-keto reductase signature 133 151 8.1E-5 T 13-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 THL1_RS18990 c855a9ae8342b21168113d2187de71e1 307 PRINTS PR00069 Aldo-keto reductase signature 239 263 8.1E-5 T 13-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 THL1_RS03790 eb828a9ed504f64bb2661aa176531b94 230 PANTHER PTHR36920 1 230 2.8E-66 T 13-09-2016 THL1_RS03790 eb828a9ed504f64bb2661aa176531b94 230 Pfam PF03922 OmpW family 24 230 1.2E-57 T 13-09-2016 IPR005618 Outer membrane protein, OmpW GO:0019867 THL1_RS03790 eb828a9ed504f64bb2661aa176531b94 230 SUPERFAMILY SSF56925 24 230 6.28E-30 T 13-09-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 THL1_RS03790 eb828a9ed504f64bb2661aa176531b94 230 PANTHER PTHR36920:SF1 1 230 2.8E-66 T 13-09-2016 THL1_RS03790 eb828a9ed504f64bb2661aa176531b94 230 Gene3D G3DSA:2.40.160.20 23 230 1.3E-64 T 13-09-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 THL1_RS03790 eb828a9ed504f64bb2661aa176531b94 230 ProSitePatterns PS00695 Enterobacterial virulence outer membrane protein signature 2. 222 230 - T 13-09-2016 IPR000758 Virulence-related outer membrane protein GO:0009279 THL1_RS09235 57e7e85b0f8b3fe9f8a1823a4ffde66b 578 Pfam PF06315 Isocitrate dehydrogenase kinase/phosphatase (AceK) 10 569 6.8E-237 T 13-09-2016 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 THL1_RS09235 57e7e85b0f8b3fe9f8a1823a4ffde66b 578 Hamap MF_00747 Isocitrate dehydrogenase kinase/phosphatase [aceK]. 2 573 43.353 T 13-09-2016 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 THL1_RS09235 57e7e85b0f8b3fe9f8a1823a4ffde66b 578 ProDom PD043552 KINASE KINASE/PHOSPHATASE ISOCITRATE DEHYDROGENASE 3.1.3.- IDH TRANSFERASE IDHK/P HYDROLASE ENZYME 10 566 0.0 T 13-09-2016 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 THL1_RS09235 57e7e85b0f8b3fe9f8a1823a4ffde66b 578 PIRSF PIRSF000719 1 577 1.3E-285 T 13-09-2016 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 THL1_RS09235 57e7e85b0f8b3fe9f8a1823a4ffde66b 578 PANTHER PTHR39559 1 578 1.5E-254 T 13-09-2016 THL1_RS08560 0b35a70096637469d0dfcfd2e62ba437 275 PANTHER PTHR30043 1 273 1.1E-91 T 13-09-2016 THL1_RS08560 0b35a70096637469d0dfcfd2e62ba437 275 Gene3D G3DSA:1.10.3720.10 68 274 1.6E-20 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS08560 0b35a70096637469d0dfcfd2e62ba437 275 SUPERFAMILY SSF161098 68 266 5.07E-24 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS08560 0b35a70096637469d0dfcfd2e62ba437 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 271 4.8E-10 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS08560 0b35a70096637469d0dfcfd2e62ba437 275 PANTHER PTHR30043:SF1 1 273 1.1E-91 T 13-09-2016 THL1_RS27075 4d2effba3fef0ba3a2d1a959e88f7bb3 387 PANTHER PTHR11496:SF68 1 387 7.5E-148 T 13-09-2016 THL1_RS27075 4d2effba3fef0ba3a2d1a959e88f7bb3 387 PANTHER PTHR11496 1 387 7.5E-148 T 13-09-2016 THL1_RS27075 4d2effba3fef0ba3a2d1a959e88f7bb3 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 11 378 3.7E-112 T 13-09-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 THL1_RS27075 4d2effba3fef0ba3a2d1a959e88f7bb3 387 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 174 202 - T 13-09-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 THL1_RS27075 4d2effba3fef0ba3a2d1a959e88f7bb3 387 SUPERFAMILY SSF56796 2 387 9.55E-115 T 13-09-2016 THL1_RS27075 4d2effba3fef0ba3a2d1a959e88f7bb3 387 Gene3D G3DSA:1.20.1090.10 186 387 1.6E-62 T 13-09-2016 THL1_RS27075 4d2effba3fef0ba3a2d1a959e88f7bb3 387 Gene3D G3DSA:3.40.50.1970 1 185 1.6E-50 T 13-09-2016 THL1_RS06685 8aa97daedf543daf3dc3609a3f2d444c 155 SMART SM00671 119 155 42.0 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS06685 8aa97daedf543daf3dc3609a3f2d444c 155 SMART SM00671 82 118 0.063 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS06685 8aa97daedf543daf3dc3609a3f2d444c 155 SUPERFAMILY SSF81901 39 154 8.11E-11 T 13-09-2016 THL1_RS06685 8aa97daedf543daf3dc3609a3f2d444c 155 Gene3D G3DSA:1.25.40.10 37 154 2.5E-14 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS22225 4a249bc8fa0b320e5f8fb1070edc9101 117 SUPERFAMILY SSF52833 4 116 2.08E-37 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS22225 4a249bc8fa0b320e5f8fb1070edc9101 117 Gene3D G3DSA:3.40.30.10 1 117 3.2E-49 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS22225 4a249bc8fa0b320e5f8fb1070edc9101 117 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 5 116 2.9E-45 T 13-09-2016 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 THL1_RS22225 4a249bc8fa0b320e5f8fb1070edc9101 117 PANTHER PTHR30041 1 116 3.2E-58 T 13-09-2016 THL1_RS22225 4a249bc8fa0b320e5f8fb1070edc9101 117 Pfam PF03960 ArsC family 7 115 1.3E-20 T 13-09-2016 IPR006660 Arsenate reductase-like THL1_RS22225 4a249bc8fa0b320e5f8fb1070edc9101 117 PANTHER PTHR30041:SF4 1 116 3.2E-58 T 13-09-2016 THL1_RS01810 e587c57b16b179f8747917ffc84c4b1e 160 PANTHER PTHR10371 10 152 1.8E-39 T 13-09-2016 THL1_RS01810 e587c57b16b179f8747917ffc84c4b1e 160 SUPERFAMILY SSF52833 11 156 5.89E-43 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS01810 e587c57b16b179f8747917ffc84c4b1e 160 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 12 152 1.5E-39 T 13-09-2016 THL1_RS01810 e587c57b16b179f8747917ffc84c4b1e 160 Gene3D G3DSA:3.40.30.10 75 158 2.5E-8 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS01810 e587c57b16b179f8747917ffc84c4b1e 160 PIRSF PIRSF000216 4 159 2.0E-43 T 13-09-2016 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 THL1_RS27325 6c5e91a56764b72fbbc9b7a3e188f702 500 SUPERFAMILY SSF53067 137 311 9.5E-45 T 13-09-2016 THL1_RS27325 6c5e91a56764b72fbbc9b7a3e188f702 500 SUPERFAMILY SSF53067 12 133 4.92E-37 T 13-09-2016 THL1_RS27325 6c5e91a56764b72fbbc9b7a3e188f702 500 SUPERFAMILY SSF109604 313 493 3.77E-51 T 13-09-2016 THL1_RS27325 6c5e91a56764b72fbbc9b7a3e188f702 500 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 12 306 3.9E-100 T 13-09-2016 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 THL1_RS27325 6c5e91a56764b72fbbc9b7a3e188f702 500 Gene3D G3DSA:3.30.420.40 8 132 1.3E-45 T 13-09-2016 THL1_RS27325 6c5e91a56764b72fbbc9b7a3e188f702 500 Gene3D G3DSA:3.30.420.150 133 311 2.0E-51 T 13-09-2016 THL1_RS27325 6c5e91a56764b72fbbc9b7a3e188f702 500 Pfam PF02541 Ppx/GppA phosphatase family 25 309 3.1E-76 T 13-09-2016 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40|UniPathway: UPA00908 THL1_RS27325 6c5e91a56764b72fbbc9b7a3e188f702 500 PANTHER PTHR30005:SF4 3 499 2.7E-206 T 13-09-2016 THL1_RS27325 6c5e91a56764b72fbbc9b7a3e188f702 500 PIRSF PIRSF001267 2 500 2.2E-195 T 13-09-2016 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40|UniPathway: UPA00908 THL1_RS27325 6c5e91a56764b72fbbc9b7a3e188f702 500 PANTHER PTHR30005 3 499 2.7E-206 T 13-09-2016 THL1_RS11405 88a8ed0171a67c72f6e6e073b7db4b1f 362 PANTHER PTHR11941:SF53 254 331 2.9E-102 T 13-09-2016 THL1_RS11405 88a8ed0171a67c72f6e6e073b7db4b1f 362 Gene3D G3DSA:3.90.226.10 8 194 2.8E-54 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS11405 88a8ed0171a67c72f6e6e073b7db4b1f 362 Pfam PF16113 Enoyl-CoA hydratase/isomerase 16 348 4.6E-117 T 13-09-2016 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 THL1_RS11405 88a8ed0171a67c72f6e6e073b7db4b1f 362 Gene3D G3DSA:1.10.12.10 274 320 4.1E-6 T 13-09-2016 IPR014748 Crontonase, C-terminal THL1_RS11405 88a8ed0171a67c72f6e6e073b7db4b1f 362 PANTHER PTHR11941:SF53 1 189 2.9E-102 T 13-09-2016 THL1_RS11405 88a8ed0171a67c72f6e6e073b7db4b1f 362 SUPERFAMILY SSF52096 258 335 1.02E-70 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS11405 88a8ed0171a67c72f6e6e073b7db4b1f 362 SUPERFAMILY SSF52096 7 189 1.02E-70 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS11405 88a8ed0171a67c72f6e6e073b7db4b1f 362 PANTHER PTHR11941 254 331 2.9E-102 T 13-09-2016 THL1_RS11405 88a8ed0171a67c72f6e6e073b7db4b1f 362 PANTHER PTHR11941 1 189 2.9E-102 T 13-09-2016 THL1_RS07315 6ecbe9d2596b3740856d08bef09e8ffa 262 SMART SM00346 15 104 2.0E-24 T 13-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 THL1_RS07315 6ecbe9d2596b3740856d08bef09e8ffa 262 Pfam PF09339 IclR helix-turn-helix domain 17 66 1.1E-14 T 13-09-2016 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 THL1_RS07315 6ecbe9d2596b3740856d08bef09e8ffa 262 Gene3D G3DSA:3.30.450.40 85 257 4.2E-43 T 13-09-2016 IPR029016 GAF domain-like THL1_RS07315 6ecbe9d2596b3740856d08bef09e8ffa 262 PANTHER PTHR30136 5 256 5.6E-54 T 13-09-2016 THL1_RS07315 6ecbe9d2596b3740856d08bef09e8ffa 262 SUPERFAMILY SSF55781 82 257 1.05E-37 T 13-09-2016 IPR029016 GAF domain-like THL1_RS07315 6ecbe9d2596b3740856d08bef09e8ffa 262 Pfam PF01614 Bacterial transcriptional regulator 131 254 2.6E-19 T 13-09-2016 IPR014757 Transcription regulator IclR, C-terminal THL1_RS07315 6ecbe9d2596b3740856d08bef09e8ffa 262 SUPERFAMILY SSF46785 15 87 3.12E-15 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07315 6ecbe9d2596b3740856d08bef09e8ffa 262 Gene3D G3DSA:1.10.10.10 8 84 1.4E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07315 6ecbe9d2596b3740856d08bef09e8ffa 262 PANTHER PTHR30136:SF10 5 256 5.6E-54 T 13-09-2016 THL1_RS23915 23032e504e013d41f1f53b7a91ace8d2 308 SUPERFAMILY SSF46955 23 118 5.49E-20 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS23915 23032e504e013d41f1f53b7a91ace8d2 308 Pfam PF13411 MerR HTH family regulatory protein 23 89 1.1E-17 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS23915 23032e504e013d41f1f53b7a91ace8d2 308 Gene3D G3DSA:1.10.1660.10 23 120 2.8E-21 T 13-09-2016 THL1_RS23915 23032e504e013d41f1f53b7a91ace8d2 308 PANTHER PTHR30204 14 253 5.1E-64 T 13-09-2016 THL1_RS23915 23032e504e013d41f1f53b7a91ace8d2 308 SMART SM00422 22 91 9.3E-19 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS23915 23032e504e013d41f1f53b7a91ace8d2 308 PANTHER PTHR30204:SF19 14 253 5.1E-64 T 13-09-2016 THL1_RS12675 bbe947a9df7e1a1d45a08318e16a5d63 579 PANTHER PTHR11632 1 132 2.0E-188 T 13-09-2016 THL1_RS12675 bbe947a9df7e1a1d45a08318e16a5d63 579 PANTHER PTHR11632 202 559 2.0E-188 T 13-09-2016 THL1_RS12675 bbe947a9df7e1a1d45a08318e16a5d63 579 Gene3D G3DSA:3.90.700.10 334 493 1.1E-31 T 13-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain THL1_RS12675 bbe947a9df7e1a1d45a08318e16a5d63 579 Gene3D G3DSA:3.50.50.60 209 313 1.8E-59 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12675 bbe947a9df7e1a1d45a08318e16a5d63 579 Gene3D G3DSA:3.50.50.60 497 558 1.8E-59 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12675 bbe947a9df7e1a1d45a08318e16a5d63 579 Gene3D G3DSA:3.50.50.60 2 135 1.8E-59 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12675 bbe947a9df7e1a1d45a08318e16a5d63 579 PANTHER PTHR11632:SF59 1 132 2.0E-188 T 13-09-2016 THL1_RS12675 bbe947a9df7e1a1d45a08318e16a5d63 579 SUPERFAMILY SSF51905 219 310 6.49E-36 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12675 bbe947a9df7e1a1d45a08318e16a5d63 579 SUPERFAMILY SSF51905 89 149 6.49E-36 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12675 bbe947a9df7e1a1d45a08318e16a5d63 579 SUPERFAMILY SSF51905 4 61 6.49E-36 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12675 bbe947a9df7e1a1d45a08318e16a5d63 579 SUPERFAMILY SSF51905 495 559 6.49E-36 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS12675 bbe947a9df7e1a1d45a08318e16a5d63 579 PANTHER PTHR11632:SF59 202 559 2.0E-188 T 13-09-2016 THL1_RS12675 bbe947a9df7e1a1d45a08318e16a5d63 579 SUPERFAMILY SSF56425 320 494 2.62E-32 T 13-09-2016 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain THL1_RS12675 bbe947a9df7e1a1d45a08318e16a5d63 579 Pfam PF00890 FAD binding domain 10 542 6.6E-103 T 13-09-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain THL1_RS27680 068620b96ccf453325b9f0ceb8b9b418 202 Pfam PF01078 Magnesium chelatase, subunit ChlI 1 94 9.3E-44 T 13-09-2016 IPR000523 Magnesium chelatase ChlI domain THL1_RS27680 068620b96ccf453325b9f0ceb8b9b418 202 PANTHER PTHR32039 1 197 2.8E-90 T 13-09-2016 THL1_RS27680 068620b96ccf453325b9f0ceb8b9b418 202 Gene3D G3DSA:3.40.50.300 1 91 1.4E-20 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27680 068620b96ccf453325b9f0ceb8b9b418 202 PANTHER PTHR32039:SF7 1 197 2.8E-90 T 13-09-2016 IPR004482 Mg chelatase-related protein THL1_RS27680 068620b96ccf453325b9f0ceb8b9b418 202 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 107 197 3.3E-28 T 13-09-2016 IPR025158 Mg chelatase-related protein, C-terminal domain THL1_RS27680 068620b96ccf453325b9f0ceb8b9b418 202 SUPERFAMILY SSF52540 1 199 5.93E-20 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01715 96542efc8f572e84e2ff62494ee0a2c4 562 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 84 107 - T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS01715 96542efc8f572e84e2ff62494ee0a2c4 562 Hamap MF_00750 Oxygen-dependent choline dehydrogenase [betA]. 3 556 63.511 T 13-09-2016 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|UniPathway: UPA00529 THL1_RS01715 96542efc8f572e84e2ff62494ee0a2c4 562 Pfam PF05199 GMC oxidoreductase 395 529 1.6E-41 T 13-09-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 THL1_RS01715 96542efc8f572e84e2ff62494ee0a2c4 562 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 261 275 - T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS01715 96542efc8f572e84e2ff62494ee0a2c4 562 PIRSF PIRSF000137 1 538 1.2E-136 T 13-09-2016 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|UniPathway: UPA00529 THL1_RS01715 96542efc8f572e84e2ff62494ee0a2c4 562 SUPERFAMILY SSF54373 297 479 4.22E-63 T 13-09-2016 THL1_RS01715 96542efc8f572e84e2ff62494ee0a2c4 562 Pfam PF00732 GMC oxidoreductase 5 302 2.0E-97 T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS01715 96542efc8f572e84e2ff62494ee0a2c4 562 TIGRFAM TIGR01810 betA: choline dehydrogenase 6 539 2.7E-280 T 13-09-2016 IPR011533 Oxygen-dependent choline dehydrogenase GO:0008812|GO:0019285 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|UniPathway: UPA00529 THL1_RS01715 96542efc8f572e84e2ff62494ee0a2c4 562 SUPERFAMILY SSF51905 1 295 2.46E-87 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01715 96542efc8f572e84e2ff62494ee0a2c4 562 SUPERFAMILY SSF51905 478 537 2.46E-87 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01715 96542efc8f572e84e2ff62494ee0a2c4 562 PANTHER PTHR11552 1 555 9.8E-258 T 13-09-2016 THL1_RS01715 96542efc8f572e84e2ff62494ee0a2c4 562 Gene3D G3DSA:3.50.50.60 472 536 8.1E-119 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01715 96542efc8f572e84e2ff62494ee0a2c4 562 Gene3D G3DSA:3.50.50.60 192 320 8.1E-119 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01715 96542efc8f572e84e2ff62494ee0a2c4 562 Gene3D G3DSA:3.50.50.60 2 129 8.1E-119 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01715 96542efc8f572e84e2ff62494ee0a2c4 562 PANTHER PTHR11552:SF135 1 555 9.8E-258 T 13-09-2016 THL1_RS11430 01bde22e56008a3b9e95d21a44533350 420 Pfam PF03573 outer membrane porin, OprD family 25 418 5.3E-157 T 13-09-2016 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 THL1_RS11430 01bde22e56008a3b9e95d21a44533350 420 Gene3D G3DSA:2.40.160.10 30 420 4.1E-154 T 13-09-2016 IPR023614 Porin domain THL1_RS11430 01bde22e56008a3b9e95d21a44533350 420 PANTHER PTHR34596 23 420 1.4E-172 T 13-09-2016 THL1_RS18250 2312a075aa8596a1b412be18baf2bd9a 204 SUPERFAMILY SSF53639 1 201 9.03E-47 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS18250 2312a075aa8596a1b412be18baf2bd9a 204 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 204 117.103 T 13-09-2016 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00904 THL1_RS18250 2312a075aa8596a1b412be18baf2bd9a 204 Gene3D G3DSA:3.40.225.10 3 201 6.2E-46 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS18250 2312a075aa8596a1b412be18baf2bd9a 204 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 195 7.4E-38 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS18250 2312a075aa8596a1b412be18baf2bd9a 204 SMART SM01007 8 196 3.2E-48 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS18250 2312a075aa8596a1b412be18baf2bd9a 204 PANTHER PTHR10640 2 201 2.2E-58 T 13-09-2016 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00904 THL1_RS18250 2312a075aa8596a1b412be18baf2bd9a 204 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 10 200 4.6E-72 T 13-09-2016 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00904 THL1_RS26050 2b53d6bc487728a3e798300e972587f8 269 SUPERFAMILY SSF51430 9 261 3.93E-49 T 13-09-2016 IPR023210 NADP-dependent oxidoreductase domain THL1_RS26050 2b53d6bc487728a3e798300e972587f8 269 PRINTS PR00069 Aldo-keto reductase signature 55 79 2.1E-7 T 13-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 THL1_RS26050 2b53d6bc487728a3e798300e972587f8 269 PRINTS PR00069 Aldo-keto reductase signature 117 135 2.1E-7 T 13-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 THL1_RS26050 2b53d6bc487728a3e798300e972587f8 269 PRINTS PR00069 Aldo-keto reductase signature 151 168 2.1E-7 T 13-09-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 THL1_RS26050 2b53d6bc487728a3e798300e972587f8 269 PANTHER PTHR11732:SF14 8 261 2.3E-52 T 13-09-2016 THL1_RS26050 2b53d6bc487728a3e798300e972587f8 269 Pfam PF00248 Aldo/keto reductase family 20 171 7.2E-30 T 13-09-2016 IPR023210 NADP-dependent oxidoreductase domain THL1_RS26050 2b53d6bc487728a3e798300e972587f8 269 Gene3D G3DSA:3.20.20.100 9 260 1.8E-41 T 13-09-2016 IPR023210 NADP-dependent oxidoreductase domain THL1_RS26050 2b53d6bc487728a3e798300e972587f8 269 PANTHER PTHR11732 8 261 2.3E-52 T 13-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta THL1_RS17385 667c8abb0b6d0e73cf4502419388e043 498 PANTHER PTHR11699:SF188 1 497 0.0 T 13-09-2016 THL1_RS17385 667c8abb0b6d0e73cf4502419388e043 498 PANTHER PTHR11699 1 497 0.0 T 13-09-2016 THL1_RS17385 667c8abb0b6d0e73cf4502419388e043 498 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 4 481 9.8E-205 T 13-09-2016 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373 THL1_RS17385 667c8abb0b6d0e73cf4502419388e043 498 Pfam PF00171 Aldehyde dehydrogenase family 15 477 2.1E-139 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS17385 667c8abb0b6d0e73cf4502419388e043 498 SUPERFAMILY SSF53720 3 482 5.89E-150 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS17385 667c8abb0b6d0e73cf4502419388e043 498 Gene3D G3DSA:3.40.309.10 260 442 4.0E-66 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS17385 667c8abb0b6d0e73cf4502419388e043 498 Gene3D G3DSA:3.40.605.10 3 259 4.6E-92 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS17385 667c8abb0b6d0e73cf4502419388e043 498 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 273 284 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS04465 7a86c666f4933f7301bd1dd029758f19 82 Pfam PF09360 Iron-binding zinc finger CDGSH type 18 42 8.9E-12 T 13-09-2016 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 THL1_RS04465 7a86c666f4933f7301bd1dd029758f19 82 Pfam PF09360 Iron-binding zinc finger CDGSH type 56 77 2.2E-6 T 13-09-2016 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 THL1_RS04465 7a86c666f4933f7301bd1dd029758f19 82 SMART SM00704 10 47 4.0E-11 T 13-09-2016 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 THL1_RS04465 7a86c666f4933f7301bd1dd029758f19 82 SMART SM00704 48 81 0.0055 T 13-09-2016 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 THL1_RS04465 7a86c666f4933f7301bd1dd029758f19 82 PANTHER PTHR13680:SF22 7 81 2.3E-24 T 13-09-2016 THL1_RS04465 7a86c666f4933f7301bd1dd029758f19 82 PANTHER PTHR13680 7 81 2.3E-24 T 13-09-2016 THL1_RS13605 abd8ab3c7a498d9916fb39d62765e772 237 SMART SM00796 6 207 7.9E-81 T 13-09-2016 IPR003833 Carboxyltransferase domain, subdomain C and D THL1_RS13605 abd8ab3c7a498d9916fb39d62765e772 237 Gene3D G3DSA:3.30.1360.40 11 85 2.6E-12 T 13-09-2016 IPR024946 Arginine repressor C-terminal-like domain THL1_RS13605 abd8ab3c7a498d9916fb39d62765e772 237 PANTHER PTHR34698:SF2 1 234 4.2E-93 T 13-09-2016 THL1_RS13605 abd8ab3c7a498d9916fb39d62765e772 237 Pfam PF02682 Allophanate hydrolase subunit 1 10 203 9.1E-62 T 13-09-2016 IPR003833 Carboxyltransferase domain, subdomain C and D THL1_RS13605 abd8ab3c7a498d9916fb39d62765e772 237 SUPERFAMILY SSF160467 8 97 5.89E-14 T 13-09-2016 THL1_RS13605 abd8ab3c7a498d9916fb39d62765e772 237 Gene3D G3DSA:2.40.100.10 94 227 6.6E-46 T 13-09-2016 IPR029000 Cyclophilin-like domain THL1_RS13605 abd8ab3c7a498d9916fb39d62765e772 237 PANTHER PTHR34698 1 234 4.2E-93 T 13-09-2016 THL1_RS13605 abd8ab3c7a498d9916fb39d62765e772 237 SUPERFAMILY SSF50891 94 223 1.21E-41 T 13-09-2016 IPR029000 Cyclophilin-like domain THL1_RS14000 38acff8b67f05de6b382517c55281fc3 504 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 319 409 4.6E-24 T 13-09-2016 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19|UniPathway: UPA00047 THL1_RS14000 38acff8b67f05de6b382517c55281fc3 504 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 415 503 6.5E-25 T 13-09-2016 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19|UniPathway: UPA00047 THL1_RS14000 38acff8b67f05de6b382517c55281fc3 504 SUPERFAMILY SSF55021 410 503 1.03E-27 T 13-09-2016 THL1_RS14000 38acff8b67f05de6b382517c55281fc3 504 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 13-09-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 THL1_RS14000 38acff8b67f05de6b382517c55281fc3 504 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 5 503 5.1E-244 T 13-09-2016 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19|UniPathway: UPA00047 THL1_RS14000 38acff8b67f05de6b382517c55281fc3 504 PANTHER PTHR10314 5 358 2.9E-201 T 13-09-2016 THL1_RS14000 38acff8b67f05de6b382517c55281fc3 504 Gene3D G3DSA:3.40.1020.10 211 394 7.3E-53 T 13-09-2016 THL1_RS14000 38acff8b67f05de6b382517c55281fc3 504 Gene3D G3DSA:3.40.1020.10 395 503 5.9E-43 T 13-09-2016 THL1_RS14000 38acff8b67f05de6b382517c55281fc3 504 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 306 3.0E-82 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS14000 38acff8b67f05de6b382517c55281fc3 504 PANTHER PTHR10314:SF30 5 358 2.9E-201 T 13-09-2016 THL1_RS14000 38acff8b67f05de6b382517c55281fc3 504 Gene3D G3DSA:3.40.50.1100 50 146 3.1E-35 T 13-09-2016 THL1_RS14000 38acff8b67f05de6b382517c55281fc3 504 SUPERFAMILY SSF53686 5 355 6.94E-106 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS18170 5bc06f3bcc2fd1265584da2ee0d38056 395 SUPERFAMILY SSF54506 2 181 5.65E-68 T 13-09-2016 THL1_RS18170 5bc06f3bcc2fd1265584da2ee0d38056 395 TIGRFAM TIGR02334 prpF: probable AcnD-accessory protein PrpF 4 395 3.1E-229 T 13-09-2016 IPR012709 2-methyl-aconitate isomerase PrpF GO:0016853|GO:0019629 UniPathway: UPA00946 THL1_RS18170 5bc06f3bcc2fd1265584da2ee0d38056 395 SUPERFAMILY SSF54506 189 393 9.26E-76 T 13-09-2016 THL1_RS18170 5bc06f3bcc2fd1265584da2ee0d38056 395 PANTHER PTHR30349:SF21 1 380 2.9E-136 T 13-09-2016 THL1_RS18170 5bc06f3bcc2fd1265584da2ee0d38056 395 PANTHER PTHR30349 1 380 2.9E-136 T 13-09-2016 THL1_RS18170 5bc06f3bcc2fd1265584da2ee0d38056 395 Gene3D G3DSA:3.10.310.10 2 194 5.6E-88 T 13-09-2016 THL1_RS18170 5bc06f3bcc2fd1265584da2ee0d38056 395 Pfam PF04303 PrpF protein 6 391 9.5E-177 T 13-09-2016 IPR007400 PrpF protein THL1_RS18170 5bc06f3bcc2fd1265584da2ee0d38056 395 Gene3D G3DSA:3.10.310.10 195 374 1.3E-78 T 13-09-2016 THL1_RS03270 0f260eb87328ab15c82f867d1dca5f83 410 Pfam PF01546 Peptidase family M20/M25/M40 82 401 1.0E-34 T 13-09-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 THL1_RS03270 0f260eb87328ab15c82f867d1dca5f83 410 SUPERFAMILY SSF53187 11 226 4.37E-84 T 13-09-2016 THL1_RS03270 0f260eb87328ab15c82f867d1dca5f83 410 SUPERFAMILY SSF53187 337 409 4.37E-84 T 13-09-2016 THL1_RS03270 0f260eb87328ab15c82f867d1dca5f83 410 Gene3D G3DSA:3.40.630.10 349 408 1.5E-104 T 13-09-2016 THL1_RS03270 0f260eb87328ab15c82f867d1dca5f83 410 Gene3D G3DSA:3.40.630.10 10 229 1.5E-104 T 13-09-2016 THL1_RS03270 0f260eb87328ab15c82f867d1dca5f83 410 PANTHER PTHR32494 5 410 4.8E-137 T 13-09-2016 THL1_RS03270 0f260eb87328ab15c82f867d1dca5f83 410 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 13 404 6.7E-112 T 13-09-2016 IPR010158 Amidase, hydantoinase/carbamoylase GO:0008152|GO:0016813 THL1_RS03270 0f260eb87328ab15c82f867d1dca5f83 410 Gene3D G3DSA:3.30.70.360 230 313 2.3E-29 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS03270 0f260eb87328ab15c82f867d1dca5f83 410 PIRSF PIRSF001235 8 410 3.5E-115 T 13-09-2016 IPR010158 Amidase, hydantoinase/carbamoylase GO:0008152|GO:0016813 THL1_RS03270 0f260eb87328ab15c82f867d1dca5f83 410 SUPERFAMILY SSF55031 217 319 5.06E-23 T 13-09-2016 IPR011650 Peptidase M20, dimerisation domain THL1_RS19220 8ed0b25e14601d82800b7fd251a328b6 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 186 2.0E-34 T 13-09-2016 IPR023214 HAD-like domain THL1_RS19220 8ed0b25e14601d82800b7fd251a328b6 223 Gene3D G3DSA:3.40.50.1000 1 19 1.9E-43 T 13-09-2016 IPR023214 HAD-like domain THL1_RS19220 8ed0b25e14601d82800b7fd251a328b6 223 Gene3D G3DSA:3.40.50.1000 83 216 1.9E-43 T 13-09-2016 IPR023214 HAD-like domain THL1_RS19220 8ed0b25e14601d82800b7fd251a328b6 223 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 124 183 2.2E-10 T 13-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THL1_RS19220 8ed0b25e14601d82800b7fd251a328b6 223 PANTHER PTHR18901 1 217 4.4E-105 T 13-09-2016 THL1_RS19220 8ed0b25e14601d82800b7fd251a328b6 223 PANTHER PTHR18901:SF24 1 217 4.4E-105 T 13-09-2016 THL1_RS19220 8ed0b25e14601d82800b7fd251a328b6 223 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 6 212 5.4E-50 T 13-09-2016 IPR006346 2-phosphoglycolate phosphatase, prokaryotic GO:0008967|GO:0046295 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181|UniPathway: UPA00865 THL1_RS19220 8ed0b25e14601d82800b7fd251a328b6 223 Gene3D G3DSA:1.10.150.240 20 82 6.9E-9 T 13-09-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 THL1_RS19220 8ed0b25e14601d82800b7fd251a328b6 223 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 180 1.8E-10 T 13-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THL1_RS19220 8ed0b25e14601d82800b7fd251a328b6 223 SUPERFAMILY SSF56784 3 217 3.47E-59 T 13-09-2016 IPR023214 HAD-like domain THL1_RS26210 d9597e9855e91f4183f01abb1d08b63b 417 TIGRFAM TIGR00277 HDIG: HDIG domain 164 255 1.5E-11 T 13-09-2016 IPR006675 HDIG domain THL1_RS26210 d9597e9855e91f4183f01abb1d08b63b 417 Pfam PF11871 Domain of unknown function (DUF3391) 8 135 2.4E-22 T 13-09-2016 IPR021812 Protein of unknown function DUF3391 THL1_RS26210 d9597e9855e91f4183f01abb1d08b63b 417 Gene3D G3DSA:1.10.3210.10 163 310 1.5E-17 T 13-09-2016 IPR006674 HD domain THL1_RS26210 d9597e9855e91f4183f01abb1d08b63b 417 Pfam PF13487 HD domain 217 271 2.1E-12 T 13-09-2016 THL1_RS26210 d9597e9855e91f4183f01abb1d08b63b 417 SUPERFAMILY SSF109604 162 325 2.9E-23 T 13-09-2016 THL1_RS26210 d9597e9855e91f4183f01abb1d08b63b 417 SMART SM00471 161 296 0.0048 T 13-09-2016 IPR003607 HD/PDEase domain THL1_RS01120 c8c61ba60f658b213a3cf771e0dfafa3 288 Gene3D G3DSA:1.10.3150.10 5 284 2.4E-75 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS01120 c8c61ba60f658b213a3cf771e0dfafa3 288 PANTHER PTHR33525:SF3 3 284 2.1E-52 T 13-09-2016 THL1_RS01120 c8c61ba60f658b213a3cf771e0dfafa3 288 SUPERFAMILY SSF109604 12 284 2.83E-65 T 13-09-2016 THL1_RS01120 c8c61ba60f658b213a3cf771e0dfafa3 288 PANTHER PTHR33525 3 284 2.1E-52 T 13-09-2016 THL1_RS01120 c8c61ba60f658b213a3cf771e0dfafa3 288 Pfam PF08668 HDOD domain 20 213 2.4E-54 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS06800 2e02f985bbf4eb87f2b5c55103db2cf8 400 PANTHER PTHR14226:SF34 184 339 1.5E-112 T 13-09-2016 THL1_RS06800 2e02f985bbf4eb87f2b5c55103db2cf8 400 PANTHER PTHR14226 10 166 1.5E-112 T 13-09-2016 THL1_RS06800 2e02f985bbf4eb87f2b5c55103db2cf8 400 SUPERFAMILY SSF52151 9 295 8.11E-47 T 13-09-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THL1_RS06800 2e02f985bbf4eb87f2b5c55103db2cf8 400 PANTHER PTHR14226:SF34 10 166 1.5E-112 T 13-09-2016 THL1_RS06800 2e02f985bbf4eb87f2b5c55103db2cf8 400 Gene3D G3DSA:3.40.1090.10 5 226 8.9E-15 T 13-09-2016 THL1_RS06800 2e02f985bbf4eb87f2b5c55103db2cf8 400 PANTHER PTHR14226 184 339 1.5E-112 T 13-09-2016 THL1_RS06800 2e02f985bbf4eb87f2b5c55103db2cf8 400 Pfam PF01734 Patatin-like phospholipase 14 226 4.5E-21 T 13-09-2016 IPR002641 Patatin/Phospholipase A2-related GO:0006629 THL1_RS02985 8c3a517c456811102d4aa6d18c51e115 252 PANTHER PTHR30349 3 250 5.0E-26 T 13-09-2016 THL1_RS02985 8c3a517c456811102d4aa6d18c51e115 252 PANTHER PTHR30349:SF5 3 250 5.0E-26 T 13-09-2016 THL1_RS02985 8c3a517c456811102d4aa6d18c51e115 252 Gene3D G3DSA:1.10.443.10 126 249 9.8E-16 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS02985 8c3a517c456811102d4aa6d18c51e115 252 Pfam PF00589 Phage integrase family 126 249 3.6E-11 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS02985 8c3a517c456811102d4aa6d18c51e115 252 Gene3D G3DSA:1.10.150.130 13 97 9.8E-9 T 13-09-2016 IPR023109 Integrase/recombinase, N-terminal THL1_RS02985 8c3a517c456811102d4aa6d18c51e115 252 SUPERFAMILY SSF56349 121 249 1.8E-18 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS02985 8c3a517c456811102d4aa6d18c51e115 252 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 16 96 5.7E-11 T 13-09-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THL1_RS27230 951c706f32cb0b1a8cf9a07cf539606d 539 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 250 1.0E-14 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS27230 951c706f32cb0b1a8cf9a07cf539606d 539 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 356 537 2.9E-8 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS27230 951c706f32cb0b1a8cf9a07cf539606d 539 SUPERFAMILY SSF161098 282 531 1.31E-34 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS27230 951c706f32cb0b1a8cf9a07cf539606d 539 Gene3D G3DSA:1.10.3720.10 10 257 5.2E-40 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS27230 951c706f32cb0b1a8cf9a07cf539606d 539 Gene3D G3DSA:1.10.3720.10 290 535 1.9E-30 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS27230 951c706f32cb0b1a8cf9a07cf539606d 539 PANTHER PTHR30183 3 386 1.1E-267 T 13-09-2016 THL1_RS27230 951c706f32cb0b1a8cf9a07cf539606d 539 PANTHER PTHR30183 403 539 1.1E-267 T 13-09-2016 THL1_RS27230 951c706f32cb0b1a8cf9a07cf539606d 539 PANTHER PTHR30183:SF2 403 539 1.1E-267 T 13-09-2016 THL1_RS27230 951c706f32cb0b1a8cf9a07cf539606d 539 PANTHER PTHR30183:SF2 3 386 1.1E-267 T 13-09-2016 THL1_RS27230 951c706f32cb0b1a8cf9a07cf539606d 539 SUPERFAMILY SSF161098 8 253 1.31E-47 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS08030 414cda423393f3cf57d5474dfdc68f2b 370 Pfam PF01435 Peptidase family M48 173 355 5.5E-11 T 13-09-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 THL1_RS08030 414cda423393f3cf57d5474dfdc68f2b 370 Gene3D G3DSA:3.30.2010.10 149 230 6.8E-8 T 13-09-2016 THL1_RS19410 ed5df3eec3cefe02073b1a119727110d 178 Gene3D G3DSA:3.40.30.10 8 169 1.2E-41 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS19410 ed5df3eec3cefe02073b1a119727110d 178 SUPERFAMILY SSF52833 41 170 1.77E-38 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS19410 ed5df3eec3cefe02073b1a119727110d 178 PANTHER PTHR10681 1 175 1.8E-58 T 13-09-2016 THL1_RS19410 ed5df3eec3cefe02073b1a119727110d 178 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 6 169 3.5E-57 T 13-09-2016 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 THL1_RS19410 ed5df3eec3cefe02073b1a119727110d 178 Pfam PF08534 Redoxin 37 159 2.0E-20 T 13-09-2016 IPR013740 Redoxin GO:0016491 THL1_RS19410 ed5df3eec3cefe02073b1a119727110d 178 PANTHER PTHR10681:SF107 1 175 1.8E-58 T 13-09-2016 THL1_RS19410 ed5df3eec3cefe02073b1a119727110d 178 ProSitePatterns PS00194 Thioredoxin family active site. 65 83 - T 13-09-2016 IPR017937 Thioredoxin, conserved site GO:0045454 THL1_RS08440 ffe825564455c4a94213044e5e039208 243 SMART SM00967 22 92 0.0039 T 13-09-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 THL1_RS08440 ffe825564455c4a94213044e5e039208 243 SUPERFAMILY SSF75217 101 243 2.03E-27 T 13-09-2016 IPR029028 Alpha/beta knot methyltransferases THL1_RS08440 ffe825564455c4a94213044e5e039208 243 Pfam PF00588 SpoU rRNA Methylase family 104 239 3.3E-25 T 13-09-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 THL1_RS08440 ffe825564455c4a94213044e5e039208 243 SUPERFAMILY SSF55315 3 89 8.0E-15 T 13-09-2016 IPR029064 50S ribosomal protein L30e-like THL1_RS08440 ffe825564455c4a94213044e5e039208 243 Gene3D G3DSA:3.30.1330.30 5 89 3.2E-16 T 13-09-2016 IPR029064 50S ribosomal protein L30e-like THL1_RS08440 ffe825564455c4a94213044e5e039208 243 Gene3D G3DSA:3.40.1280.10 102 242 1.4E-30 T 13-09-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THL1_RS08440 ffe825564455c4a94213044e5e039208 243 PANTHER PTHR12029 1 241 1.1E-36 T 13-09-2016 THL1_RS06975 03bafce4901efbfd7fee4f369490c405 311 Gene3D G3DSA:3.40.250.10 103 226 1.5E-38 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS06975 03bafce4901efbfd7fee4f369490c405 311 Hamap MF_00469 UPF0176 protein YceA [yceA]. 2 254 46.257 T 13-09-2016 IPR020936 Uncharacterised protein family UPF0176 THL1_RS06975 03bafce4901efbfd7fee4f369490c405 311 Pfam PF00581 Rhodanese-like domain 119 210 4.0E-6 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS06975 03bafce4901efbfd7fee4f369490c405 311 SMART SM00450 113 214 2.6E-17 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS06975 03bafce4901efbfd7fee4f369490c405 311 PANTHER PTHR22778:SF12 3 290 2.4E-111 T 13-09-2016 THL1_RS06975 03bafce4901efbfd7fee4f369490c405 311 SUPERFAMILY SSF52821 90 225 1.51E-29 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS06975 03bafce4901efbfd7fee4f369490c405 311 PANTHER PTHR22778 3 290 2.4E-111 T 13-09-2016 THL1_RS02270 ec53066a81a06d3c8e9cc601c0a31afe 185 Gene3D G3DSA:1.10.260.40 14 106 1.3E-16 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS02270 ec53066a81a06d3c8e9cc601c0a31afe 185 SMART SM00530 13 68 6.9E-10 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS02270 ec53066a81a06d3c8e9cc601c0a31afe 185 PANTHER PTHR10245:SF53 10 185 2.6E-39 T 13-09-2016 THL1_RS02270 ec53066a81a06d3c8e9cc601c0a31afe 185 SUPERFAMILY SSF51182 54 184 7.43E-28 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS02270 ec53066a81a06d3c8e9cc601c0a31afe 185 Pfam PF01381 Helix-turn-helix 14 68 3.2E-10 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS02270 ec53066a81a06d3c8e9cc601c0a31afe 185 PANTHER PTHR10245 10 185 2.6E-39 T 13-09-2016 THL1_RS02270 ec53066a81a06d3c8e9cc601c0a31afe 185 SUPERFAMILY SSF47413 10 74 6.48E-14 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS02270 ec53066a81a06d3c8e9cc601c0a31afe 185 Gene3D G3DSA:2.60.120.10 107 185 1.0E-20 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS02270 ec53066a81a06d3c8e9cc601c0a31afe 185 Pfam PF07883 Cupin domain 114 184 1.2E-13 T 13-09-2016 IPR013096 Cupin 2, conserved barrel THL1_RS18610 cfa8eef8e6538d7d5e78213269989915 1051 Gene3D G3DSA:3.40.50.300 1 167 8.5E-25 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18610 cfa8eef8e6538d7d5e78213269989915 1051 Gene3D G3DSA:3.40.50.300 566 582 8.5E-25 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18610 cfa8eef8e6538d7d5e78213269989915 1051 Gene3D G3DSA:3.40.50.300 890 1015 8.5E-25 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18610 cfa8eef8e6538d7d5e78213269989915 1051 SUPERFAMILY SSF52540 886 1013 6.32E-12 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18610 cfa8eef8e6538d7d5e78213269989915 1051 SUPERFAMILY SSF52540 651 690 6.32E-12 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18610 cfa8eef8e6538d7d5e78213269989915 1051 SUPERFAMILY SSF52540 469 612 6.32E-12 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18610 cfa8eef8e6538d7d5e78213269989915 1051 SUPERFAMILY SSF52540 1 170 3.14E-19 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18610 cfa8eef8e6538d7d5e78213269989915 1051 SUPERFAMILY SSF52540 912 1012 3.14E-19 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14500 c218ac944912ad082c1a0aecebe4056f 123 Gene3D G3DSA:3.30.1330.40 6 122 2.8E-29 T 13-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THL1_RS14500 c218ac944912ad082c1a0aecebe4056f 123 Pfam PF01042 Endoribonuclease L-PSP 16 122 6.1E-22 T 13-09-2016 IPR006175 YjgF/YER057c/UK114 family THL1_RS14500 c218ac944912ad082c1a0aecebe4056f 123 SUPERFAMILY SSF55298 5 122 7.54E-29 T 13-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THL1_RS14500 c218ac944912ad082c1a0aecebe4056f 123 PANTHER PTHR11803 19 123 8.0E-29 T 13-09-2016 IPR006175 YjgF/YER057c/UK114 family THL1_RS00430 7cd5a3aa8ffcb5ae03962dcc74de8093 408 Pfam PF07670 Nucleoside recognition 51 156 1.4E-6 T 13-09-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 THL1_RS00430 7cd5a3aa8ffcb5ae03962dcc74de8093 408 Pfam PF07670 Nucleoside recognition 275 378 1.4E-6 T 13-09-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 THL1_RS00430 7cd5a3aa8ffcb5ae03962dcc74de8093 408 PIRSF PIRSF036542 1 408 7.7E-196 T 13-09-2016 IPR011415 Predicted bifunctional spore maturation protein, fused SpmA/SpmB THL1_RS00430 7cd5a3aa8ffcb5ae03962dcc74de8093 408 PANTHER PTHR35793:SF2 2 408 4.4E-242 T 13-09-2016 THL1_RS00430 7cd5a3aa8ffcb5ae03962dcc74de8093 408 PANTHER PTHR35793 2 408 4.4E-242 T 13-09-2016 THL1_RS03180 6a1accb3681f156497eff09e09a9ce22 83 PANTHER PTHR32089:SF64 1 74 2.6E-13 T 13-09-2016 THL1_RS03180 6a1accb3681f156497eff09e09a9ce22 83 Gene3D G3DSA:1.10.287.950 4 53 4.2E-6 T 13-09-2016 THL1_RS03180 6a1accb3681f156497eff09e09a9ce22 83 PANTHER PTHR32089 1 74 2.6E-13 T 13-09-2016 THL1_RS03180 6a1accb3681f156497eff09e09a9ce22 83 SUPERFAMILY SSF58104 3 77 2.75E-9 T 13-09-2016 THL1_RS08780 68c670f7e65d4d1a1325ab454310ad1b 107 PANTHER PTHR33930 10 107 3.2E-21 T 13-09-2016 THL1_RS08780 68c670f7e65d4d1a1325ab454310ad1b 107 Pfam PF02627 Carboxymuconolactone decarboxylase family 18 99 3.2E-14 T 13-09-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS08780 68c670f7e65d4d1a1325ab454310ad1b 107 PANTHER PTHR33930:SF2 10 107 3.2E-21 T 13-09-2016 THL1_RS08780 68c670f7e65d4d1a1325ab454310ad1b 107 SUPERFAMILY SSF69118 8 106 1.57E-19 T 13-09-2016 IPR029032 AhpD-like THL1_RS08780 68c670f7e65d4d1a1325ab454310ad1b 107 Gene3D G3DSA:1.20.1290.10 9 106 8.0E-23 T 13-09-2016 IPR029032 AhpD-like THL1_RS01495 62f5e185787eb812b751c40718d317ec 170 PANTHER PTHR11608 1 170 1.9E-67 T 13-09-2016 THL1_RS01495 62f5e185787eb812b751c40718d317ec 170 Pfam PF00156 Phosphoribosyl transferase domain 27 136 2.5E-15 T 13-09-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 THL1_RS01495 62f5e185787eb812b751c40718d317ec 170 Gene3D G3DSA:3.40.50.2020 8 151 4.3E-34 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS01495 62f5e185787eb812b751c40718d317ec 170 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 1 168 26.857 T 13-09-2016 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 THL1_RS01495 62f5e185787eb812b751c40718d317ec 170 SUPERFAMILY SSF53271 8 151 3.54E-31 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS17445 334bf3891615a84ff7dd92bc19bac500 398 Gene3D G3DSA:1.20.140.10 222 396 1.4E-28 T 13-09-2016 THL1_RS17445 334bf3891615a84ff7dd92bc19bac500 398 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 219 2.6E-21 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS17445 334bf3891615a84ff7dd92bc19bac500 398 SUPERFAMILY SSF56645 2 244 2.23E-79 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS17445 334bf3891615a84ff7dd92bc19bac500 398 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 121 4.8E-24 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS17445 334bf3891615a84ff7dd92bc19bac500 398 PANTHER PTHR10909 1 347 2.6E-157 T 13-09-2016 THL1_RS17445 334bf3891615a84ff7dd92bc19bac500 398 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 395 1.7E-20 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS17445 334bf3891615a84ff7dd92bc19bac500 398 Gene3D G3DSA:1.10.540.10 1 121 4.7E-28 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS17445 334bf3891615a84ff7dd92bc19bac500 398 PANTHER PTHR10909:SF229 1 347 2.6E-157 T 13-09-2016 THL1_RS17445 334bf3891615a84ff7dd92bc19bac500 398 PANTHER PTHR10909:SF229 366 396 2.6E-157 T 13-09-2016 THL1_RS17445 334bf3891615a84ff7dd92bc19bac500 398 SUPERFAMILY SSF47203 231 396 5.86E-22 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS17445 334bf3891615a84ff7dd92bc19bac500 398 PANTHER PTHR10909 366 396 2.6E-157 T 13-09-2016 THL1_RS17445 334bf3891615a84ff7dd92bc19bac500 398 Gene3D G3DSA:2.40.110.10 124 221 1.5E-37 T 13-09-2016 THL1_RS02175 dbc9185601332c4b64d87d57f4c29328 241 PANTHER PTHR10992 5 237 6.6E-19 T 13-09-2016 THL1_RS02175 dbc9185601332c4b64d87d57f4c29328 241 PANTHER PTHR10992:SF812 5 237 6.6E-19 T 13-09-2016 THL1_RS02175 dbc9185601332c4b64d87d57f4c29328 241 Pfam PF12697 Alpha/beta hydrolase family 6 230 2.4E-9 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS02175 dbc9185601332c4b64d87d57f4c29328 241 Gene3D G3DSA:3.40.50.1820 44 237 7.1E-28 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS02175 dbc9185601332c4b64d87d57f4c29328 241 SUPERFAMILY SSF53474 5 237 5.0E-29 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS21705 d93928070ff644a517fc58005f83fa6d 458 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 4 455 1.0E-215 T 13-09-2016 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 THL1_RS21705 d93928070ff644a517fc58005f83fa6d 458 SUPERFAMILY SSF143548 17 158 1.52E-43 T 13-09-2016 IPR029009 Allosteric substrate binding domain THL1_RS21705 d93928070ff644a517fc58005f83fa6d 458 PANTHER PTHR30182:SF1 1 455 2.8E-242 T 13-09-2016 THL1_RS21705 d93928070ff644a517fc58005f83fa6d 458 PANTHER PTHR30182 1 455 2.8E-242 T 13-09-2016 THL1_RS21705 d93928070ff644a517fc58005f83fa6d 458 Gene3D G3DSA:3.30.1330.90 11 157 1.2E-51 T 13-09-2016 IPR029009 Allosteric substrate binding domain THL1_RS21705 d93928070ff644a517fc58005f83fa6d 458 Pfam PF03313 Serine dehydratase alpha chain 188 452 4.1E-106 T 13-09-2016 IPR005130 Serine dehydratase-like, alpha subunit THL1_RS21705 d93928070ff644a517fc58005f83fa6d 458 Pfam PF03315 Serine dehydratase beta chain 4 156 2.1E-56 T 13-09-2016 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 THL1_RS22875 04550dc58f80d7f6bf32f8b3376b0b86 237 Pfam PF00440 Bacterial regulatory proteins, tetR family 40 83 4.3E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS22875 04550dc58f80d7f6bf32f8b3376b0b86 237 PANTHER PTHR30055 24 103 1.4E-35 T 13-09-2016 THL1_RS22875 04550dc58f80d7f6bf32f8b3376b0b86 237 PANTHER PTHR30055:SF2 24 103 1.4E-35 T 13-09-2016 THL1_RS22875 04550dc58f80d7f6bf32f8b3376b0b86 237 SUPERFAMILY SSF46689 29 107 5.13E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS22875 04550dc58f80d7f6bf32f8b3376b0b86 237 PANTHER PTHR30055 122 237 1.4E-35 T 13-09-2016 THL1_RS22875 04550dc58f80d7f6bf32f8b3376b0b86 237 PANTHER PTHR30055:SF2 122 237 1.4E-35 T 13-09-2016 THL1_RS22875 04550dc58f80d7f6bf32f8b3376b0b86 237 Gene3D G3DSA:1.10.357.10 34 234 9.2E-32 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS19580 a031acb27b78dc97aad96a8af8412929 564 SUPERFAMILY SSF55874 484 561 1.55E-5 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19580 a031acb27b78dc97aad96a8af8412929 564 SUPERFAMILY SSF55874 435 455 1.55E-5 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19580 a031acb27b78dc97aad96a8af8412929 564 SUPERFAMILY SSF81606 228 379 2.88E-5 T 13-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 THL1_RS19580 a031acb27b78dc97aad96a8af8412929 564 SMART SM00448 5 118 5.4E-36 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS19580 a031acb27b78dc97aad96a8af8412929 564 SUPERFAMILY SSF52172 3 145 9.82E-39 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS19580 a031acb27b78dc97aad96a8af8412929 564 Gene3D G3DSA:3.40.50.2300 3 130 8.3E-38 T 13-09-2016 THL1_RS19580 a031acb27b78dc97aad96a8af8412929 564 SMART SM00331 180 380 1.0E-5 T 13-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 THL1_RS19580 a031acb27b78dc97aad96a8af8412929 564 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 192 379 1.6E-35 T 13-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 THL1_RS19580 a031acb27b78dc97aad96a8af8412929 564 Pfam PF00072 Response regulator receiver domain 7 118 4.9E-24 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS19580 a031acb27b78dc97aad96a8af8412929 564 Gene3D G3DSA:3.30.565.10 433 563 6.8E-5 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS19580 a031acb27b78dc97aad96a8af8412929 564 PANTHER PTHR24423 3 159 1.4E-38 T 13-09-2016 THL1_RS11220 99640af58a6ab425f8badcd4ba8f538b 566 PIRSF PIRSF001294 1 564 8.3E-245 T 13-09-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 THL1_RS11220 99640af58a6ab425f8badcd4ba8f538b 566 PANTHER PTHR30607 2 566 0.0 T 13-09-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 THL1_RS11220 99640af58a6ab425f8badcd4ba8f538b 566 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 5 562 4.6E-230 T 13-09-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 THL1_RS11220 99640af58a6ab425f8badcd4ba8f538b 566 Pfam PF03814 Potassium-transporting ATPase A subunit 11 560 7.6E-245 T 13-09-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 THL1_RS11220 99640af58a6ab425f8badcd4ba8f538b 566 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 2 562 35.242 T 13-09-2016 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 THL1_RS05695 b8955edfdb6d3a9e2c08a57e9665cf60 212 PANTHER PTHR11260:SF144 4 198 4.7E-54 T 13-09-2016 THL1_RS05695 b8955edfdb6d3a9e2c08a57e9665cf60 212 PANTHER PTHR11260 4 198 4.7E-54 T 13-09-2016 THL1_RS05695 b8955edfdb6d3a9e2c08a57e9665cf60 212 Gene3D G3DSA:3.40.30.10 7 85 7.6E-20 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS05695 b8955edfdb6d3a9e2c08a57e9665cf60 212 SUPERFAMILY SSF52833 5 86 1.14E-19 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS05695 b8955edfdb6d3a9e2c08a57e9665cf60 212 Pfam PF13417 Glutathione S-transferase, N-terminal domain 11 81 1.5E-13 T 13-09-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THL1_RS05695 b8955edfdb6d3a9e2c08a57e9665cf60 212 SUPERFAMILY SSF47616 84 201 4.8E-13 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS05695 b8955edfdb6d3a9e2c08a57e9665cf60 212 Gene3D G3DSA:1.20.1050.10 90 208 3.6E-40 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS20680 3415d55854dd13f40c1b3453a6aea777 193 SUPERFAMILY SSF81452 16 192 2.09E-38 T 13-09-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 THL1_RS20680 3415d55854dd13f40c1b3453a6aea777 193 PANTHER PTHR11403 18 193 2.7E-34 T 13-09-2016 IPR024791 Cytochrome c oxidase subunit III GO:0015002|GO:0016020|GO:0019646 THL1_RS20680 3415d55854dd13f40c1b3453a6aea777 193 Pfam PF00510 Cytochrome c oxidase subunit III 20 191 5.7E-15 T 13-09-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 THL1_RS20680 3415d55854dd13f40c1b3453a6aea777 193 PANTHER PTHR11403:SF6 18 193 2.7E-34 T 13-09-2016 THL1_RS20680 3415d55854dd13f40c1b3453a6aea777 193 Gene3D G3DSA:1.20.120.80 18 192 1.5E-38 T 13-09-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 THL1_RS02695 d5aa15b4068abd433812e2c1256ac910 408 PANTHER PTHR33217 10 407 2.5E-182 T 13-09-2016 THL1_RS02695 d5aa15b4068abd433812e2c1256ac910 408 ProSitePatterns PS01007 Transposases, Mutator family, signature. 239 263 - T 13-09-2016 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 THL1_RS02695 d5aa15b4068abd433812e2c1256ac910 408 Pfam PF00872 Transposase, Mutator family 17 384 2.2E-114 T 13-09-2016 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 THL1_RS21235 b8cd5531a29637fba753f4d2aaf39a50 651 Gene3D G3DSA:3.30.300.30 518 625 1.3E-27 T 13-09-2016 THL1_RS21235 b8cd5531a29637fba753f4d2aaf39a50 651 PANTHER PTHR24095:SF178 20 643 0.0 T 13-09-2016 THL1_RS21235 b8cd5531a29637fba753f4d2aaf39a50 651 PANTHER PTHR24095 20 643 0.0 T 13-09-2016 THL1_RS21235 b8cd5531a29637fba753f4d2aaf39a50 651 SUPERFAMILY SSF56801 12 642 1.19E-184 T 13-09-2016 THL1_RS21235 b8cd5531a29637fba753f4d2aaf39a50 651 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 24 81 2.2E-22 T 13-09-2016 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118 THL1_RS21235 b8cd5531a29637fba753f4d2aaf39a50 651 Gene3D G3DSA:3.40.50.980 80 266 2.6E-42 T 13-09-2016 THL1_RS21235 b8cd5531a29637fba753f4d2aaf39a50 651 Gene3D G3DSA:3.40.50.980 267 429 7.2E-30 T 13-09-2016 THL1_RS21235 b8cd5531a29637fba753f4d2aaf39a50 651 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 2 645 52.264 T 13-09-2016 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: REACT_13433 THL1_RS21235 b8cd5531a29637fba753f4d2aaf39a50 651 Pfam PF13193 AMP-binding enzyme C-terminal domain 531 609 9.9E-26 T 13-09-2016 IPR025110 AMP-binding enzyme C-terminal domain THL1_RS21235 b8cd5531a29637fba753f4d2aaf39a50 651 ProSitePatterns PS00455 Putative AMP-binding domain signature. 261 272 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS21235 b8cd5531a29637fba753f4d2aaf39a50 651 Pfam PF00501 AMP-binding enzyme 83 522 1.2E-90 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS21235 b8cd5531a29637fba753f4d2aaf39a50 651 Gene3D G3DSA:2.30.38.10 439 515 3.8E-7 T 13-09-2016 THL1_RS21235 b8cd5531a29637fba753f4d2aaf39a50 651 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 20 643 0.0 T 13-09-2016 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-6672|MetaCyc: PWY-7118|Reactome: REACT_13433 THL1_RS20900 945e6630b24f3c4aa7dfcbe3568a96ff 300 PIRSF PIRSF015582 1 296 3.1E-71 T 13-09-2016 IPR011206 Citrate lyase beta subunit-like THL1_RS20900 945e6630b24f3c4aa7dfcbe3568a96ff 300 Gene3D G3DSA:3.20.20.60 7 236 4.1E-56 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS20900 945e6630b24f3c4aa7dfcbe3568a96ff 300 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 9 227 8.9E-36 T 13-09-2016 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 THL1_RS20900 945e6630b24f3c4aa7dfcbe3568a96ff 300 PANTHER PTHR32308 8 294 1.0E-67 T 13-09-2016 IPR011206 Citrate lyase beta subunit-like THL1_RS20900 945e6630b24f3c4aa7dfcbe3568a96ff 300 SUPERFAMILY SSF51621 7 236 9.07E-49 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS16655 cb147223a333d76af403117d3505deb2 799 SUPERFAMILY SSF52540 1 167 7.15E-24 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16655 cb147223a333d76af403117d3505deb2 799 SUPERFAMILY SSF52540 438 628 7.15E-24 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16655 cb147223a333d76af403117d3505deb2 799 Gene3D G3DSA:3.40.50.300 6 185 7.6E-21 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16655 cb147223a333d76af403117d3505deb2 799 Gene3D G3DSA:3.40.50.300 535 628 7.6E-21 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16655 cb147223a333d76af403117d3505deb2 799 Pfam PF02463 RecF/RecN/SMC N terminal domain 4 628 2.7E-14 T 13-09-2016 IPR003395 RecF/RecN/SMC, N-terminal THL1_RS16655 cb147223a333d76af403117d3505deb2 799 Gene3D G3DSA:3.40.50.300 345 406 2.2E-4 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16655 cb147223a333d76af403117d3505deb2 799 SMART SM00382 18 644 0.0015 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS17715 10646677d34d5b5e24c012b456ca9a3e 287 PANTHER PTHR33408 1 120 1.5E-38 T 13-09-2016 THL1_RS17715 10646677d34d5b5e24c012b456ca9a3e 287 Pfam PF13751 Transposase DDE domain 160 273 4.6E-15 T 13-09-2016 IPR025668 Transposase DDE domain THL1_RS17715 10646677d34d5b5e24c012b456ca9a3e 287 PANTHER PTHR33408:SF2 1 120 1.5E-38 T 13-09-2016 THL1_RS17715 10646677d34d5b5e24c012b456ca9a3e 287 Pfam PF05598 Transposase domain (DUF772) 55 117 5.5E-16 T 13-09-2016 IPR008490 Transposase InsH, N-terminal THL1_RS17990 d1649041c0dfe825dbd28d8e10305731 426 Gene3D G3DSA:1.10.8.60 316 417 1.8E-38 T 13-09-2016 THL1_RS17990 d1649041c0dfe825dbd28d8e10305731 426 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 10 411 1.1E-208 T 13-09-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 THL1_RS17990 d1649041c0dfe825dbd28d8e10305731 426 Pfam PF07724 AAA domain (Cdc48 subfamily) 113 311 2.4E-50 T 13-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 THL1_RS17990 d1649041c0dfe825dbd28d8e10305731 426 PANTHER PTHR11262 1 417 7.5E-250 T 13-09-2016 THL1_RS17990 d1649041c0dfe825dbd28d8e10305731 426 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 4 415 53.928 T 13-09-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 THL1_RS17990 d1649041c0dfe825dbd28d8e10305731 426 SUPERFAMILY SSF52540 65 404 4.95E-74 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17990 d1649041c0dfe825dbd28d8e10305731 426 SMART SM00382 112 333 9.7E-11 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS17990 d1649041c0dfe825dbd28d8e10305731 426 Gene3D G3DSA:3.40.50.300 67 254 4.1E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17990 d1649041c0dfe825dbd28d8e10305731 426 Gene3D G3DSA:3.40.50.300 294 311 4.1E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17990 d1649041c0dfe825dbd28d8e10305731 426 SMART SM01086 317 412 9.9E-35 T 13-09-2016 IPR019489 Clp ATPase, C-terminal THL1_RS17990 d1649041c0dfe825dbd28d8e10305731 426 SMART SM00994 13 52 2.5E-24 T 13-09-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 THL1_RS17990 d1649041c0dfe825dbd28d8e10305731 426 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 394 8.7E-16 T 13-09-2016 IPR019489 Clp ATPase, C-terminal THL1_RS17990 d1649041c0dfe825dbd28d8e10305731 426 SUPERFAMILY SSF57716 14 49 1.14E-11 T 13-09-2016 THL1_RS17990 d1649041c0dfe825dbd28d8e10305731 426 Pfam PF06689 ClpX C4-type zinc finger 14 51 1.0E-20 T 13-09-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 Pfam PF02954 Bacterial regulatory protein, Fis family 398 438 2.4E-9 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 404 421 5.4E-8 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 421 440 5.4E-8 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 PANTHER PTHR32071 5 440 5.3E-250 T 13-09-2016 THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 Gene3D G3DSA:3.40.50.300 144 318 6.7E-56 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 Gene3D G3DSA:1.10.10.60 367 440 4.2E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 PANTHER PTHR32071:SF11 5 440 5.3E-250 T 13-09-2016 THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 Gene3D G3DSA:1.10.8.60 319 366 1.4E-20 T 13-09-2016 THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 SUPERFAMILY SSF46689 358 440 3.81E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 SUPERFAMILY SSF52172 3 190 2.7E-42 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 Pfam PF00072 Response regulator receiver domain 7 115 2.2E-26 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 Pfam PF00158 Sigma-54 interaction domain 146 312 5.1E-65 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 Gene3D G3DSA:3.40.50.2300 2 128 2.8E-34 T 13-09-2016 THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 359 368 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 SMART SM00382 166 309 4.2E-10 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 170 183 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 SMART SM00448 5 116 1.7E-29 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS18980 631868955e399ff3ffb2b79105089e87 440 SUPERFAMILY SSF52540 146 375 5.16E-68 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS23655 6249e0a72f87f304488946381e8f6e29 160 PANTHER PTHR11592:SF40 4 160 7.1E-83 T 13-09-2016 THL1_RS23655 6249e0a72f87f304488946381e8f6e29 160 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 13-09-2016 IPR029759 Glutathione peroxidase active site THL1_RS23655 6249e0a72f87f304488946381e8f6e29 160 Pfam PF00255 Glutathione peroxidase 4 110 3.3E-40 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS23655 6249e0a72f87f304488946381e8f6e29 160 PANTHER PTHR11592 4 160 7.1E-83 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS23655 6249e0a72f87f304488946381e8f6e29 160 Gene3D G3DSA:3.40.30.10 4 159 2.2E-63 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS23655 6249e0a72f87f304488946381e8f6e29 160 PRINTS PR01011 Glutathione peroxidase family signature 22 39 1.6E-19 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS23655 6249e0a72f87f304488946381e8f6e29 160 PRINTS PR01011 Glutathione peroxidase family signature 57 73 1.6E-19 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS23655 6249e0a72f87f304488946381e8f6e29 160 PRINTS PR01011 Glutathione peroxidase family signature 121 130 1.6E-19 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS23655 6249e0a72f87f304488946381e8f6e29 160 PIRSF PIRSF000303 1 160 4.4E-62 T 13-09-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 THL1_RS23655 6249e0a72f87f304488946381e8f6e29 160 SUPERFAMILY SSF52833 4 159 5.42E-57 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS10295 ed2e63fa6295e0ff72cf4a1e00c640b7 791 PANTHER PTHR33406 137 774 4.0E-159 T 13-09-2016 THL1_RS10295 ed2e63fa6295e0ff72cf4a1e00c640b7 791 PANTHER PTHR33406 1 102 4.0E-159 T 13-09-2016 THL1_RS10295 ed2e63fa6295e0ff72cf4a1e00c640b7 791 SUPERFAMILY SSF82866 576 777 4.84E-37 T 13-09-2016 THL1_RS10295 ed2e63fa6295e0ff72cf4a1e00c640b7 791 Pfam PF03176 MMPL family 476 773 3.1E-28 T 13-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 THL1_RS10295 ed2e63fa6295e0ff72cf4a1e00c640b7 791 PANTHER PTHR33406:SF2 1 102 4.0E-159 T 13-09-2016 THL1_RS10295 ed2e63fa6295e0ff72cf4a1e00c640b7 791 SUPERFAMILY SSF82866 201 392 2.35E-26 T 13-09-2016 THL1_RS10295 ed2e63fa6295e0ff72cf4a1e00c640b7 791 PANTHER PTHR33406:SF2 137 774 4.0E-159 T 13-09-2016 THL1_RS10295 ed2e63fa6295e0ff72cf4a1e00c640b7 791 Gene3D G3DSA:1.20.1640.10 197 402 6.4E-27 T 13-09-2016 THL1_RS10295 ed2e63fa6295e0ff72cf4a1e00c640b7 791 Gene3D G3DSA:1.20.1640.10 577 780 2.9E-30 T 13-09-2016 THL1_RS05125 1f4cc70e66d714c1ee71f3e4e3461ee1 278 PANTHER PTHR38684 2 276 5.3E-57 T 13-09-2016 THL1_RS24045 5bb8b7325cd98ce306e0527b09b43566 110 PANTHER PTHR33713 20 97 5.9E-16 T 13-09-2016 THL1_RS24045 5bb8b7325cd98ce306e0527b09b43566 110 PANTHER PTHR33713:SF1 20 97 5.9E-16 T 13-09-2016 THL1_RS05290 be11b7024cd5c8787812480e817aa52e 95 SUPERFAMILY SSF141000 3 93 1.28E-28 T 13-09-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 THL1_RS05290 be11b7024cd5c8787812480e817aa52e 95 PANTHER PTHR15004 1 95 4.2E-29 T 13-09-2016 THL1_RS05290 be11b7024cd5c8787812480e817aa52e 95 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 90 3.9E-18 T 13-09-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 THL1_RS05290 be11b7024cd5c8787812480e817aa52e 95 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 23.282 T 13-09-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 THL1_RS05290 be11b7024cd5c8787812480e817aa52e 95 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 1.9E-28 T 13-09-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 THL1_RS05290 be11b7024cd5c8787812480e817aa52e 95 PANTHER PTHR15004:SF0 1 95 4.2E-29 T 13-09-2016 THL1_RS06145 e433287b725f4ceff14f49932108f1bf 288 PANTHER PTHR35007:SF1 65 288 2.3E-22 T 13-09-2016 THL1_RS06145 e433287b725f4ceff14f49932108f1bf 288 Pfam PF00482 Type II secretion system (T2SS), protein F 121 244 1.8E-12 T 13-09-2016 IPR018076 Type II secretion system F domain THL1_RS06145 e433287b725f4ceff14f49932108f1bf 288 PANTHER PTHR35007 65 288 2.3E-22 T 13-09-2016 THL1_RS23625 bd39e07192099dd33eb171faac77b9a2 195 SUPERFAMILY SSF159275 2 183 1.83E-41 T 13-09-2016 THL1_RS23625 bd39e07192099dd33eb171faac77b9a2 195 Pfam PF06475 Putative glycolipid-binding 4 183 5.7E-49 T 13-09-2016 IPR009467 Putative glycolipid-binding protein THL1_RS11335 615083044f4de915871fa196771e6944 243 PIRSF PIRSF009120 1 243 1.1E-102 T 13-09-2016 IPR016545 Uncharacterised conserved protein UCP009120, proteasome-type protease, Sll0069 THL1_RS11335 615083044f4de915871fa196771e6944 243 SUPERFAMILY SSF56235 2 239 1.93E-35 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS11335 615083044f4de915871fa196771e6944 243 Pfam PF00227 Proteasome subunit 4 182 1.5E-8 T 13-09-2016 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: REACT_11045|Reactome: REACT_13|Reactome: REACT_13635|Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_383|Reactome: REACT_578|Reactome: REACT_6185|Reactome: REACT_6850 THL1_RS11335 615083044f4de915871fa196771e6944 243 Gene3D G3DSA:3.60.20.10 2 201 3.1E-16 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS00120 756535e785e9c95ff9d3dfea8aa20844 184 Pfam PF01300 Telomere recombination 13 181 1.8E-41 T 13-09-2016 IPR006070 YrdC-like domain GO:0003725 THL1_RS00120 756535e785e9c95ff9d3dfea8aa20844 184 SUPERFAMILY SSF55821 4 183 1.92E-53 T 13-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain THL1_RS00120 756535e785e9c95ff9d3dfea8aa20844 184 Gene3D G3DSA:3.90.870.10 4 183 8.4E-55 T 13-09-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain THL1_RS00120 756535e785e9c95ff9d3dfea8aa20844 184 PANTHER PTHR17490:SF8 6 180 6.3E-92 T 13-09-2016 THL1_RS00120 756535e785e9c95ff9d3dfea8aa20844 184 Hamap MF_01852 Threonylcarbamoyl-AMP synthase [tsaC]. 4 183 38.099 T 13-09-2016 IPR023535 Threonylcarbamoyl-AMP synthase GO:0002949|GO:0005524 THL1_RS00120 756535e785e9c95ff9d3dfea8aa20844 184 PANTHER PTHR17490 6 180 6.3E-92 T 13-09-2016 THL1_RS13830 bbd17998e6a397de51436311cde33a24 487 SMART SM00388 269 333 1.2E-8 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS13830 bbd17998e6a397de51436311cde33a24 487 Gene3D G3DSA:3.30.565.10 335 478 9.1E-30 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS13830 bbd17998e6a397de51436311cde33a24 487 Gene3D G3DSA:1.10.287.130 271 326 2.0E-10 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS13830 bbd17998e6a397de51436311cde33a24 487 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 378 480 2.0E-17 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS13830 bbd17998e6a397de51436311cde33a24 487 PANTHER PTHR24423 111 221 2.1E-39 T 13-09-2016 THL1_RS13830 bbd17998e6a397de51436311cde33a24 487 PANTHER PTHR24423 267 482 2.1E-39 T 13-09-2016 THL1_RS13830 bbd17998e6a397de51436311cde33a24 487 SUPERFAMILY SSF47384 269 329 1.59E-10 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS13830 bbd17998e6a397de51436311cde33a24 487 SMART SM00387 374 482 5.9E-23 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS13830 bbd17998e6a397de51436311cde33a24 487 SUPERFAMILY SSF55874 334 478 4.85E-28 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS13830 bbd17998e6a397de51436311cde33a24 487 Pfam PF00512 His Kinase A (phospho-acceptor) domain 270 325 2.8E-10 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS13830 bbd17998e6a397de51436311cde33a24 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 460 3.7E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS13830 bbd17998e6a397de51436311cde33a24 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 441 3.7E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS13830 bbd17998e6a397de51436311cde33a24 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 427 3.7E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS03430 d03146b2d0f5d21ab640c2e6e9e1cb6a 225 SUPERFAMILY SSF110997 67 138 1.96E-8 T 13-09-2016 IPR007730 Sporulation-related domain GO:0042834 THL1_RS03430 d03146b2d0f5d21ab640c2e6e9e1cb6a 225 Pfam PF05036 Sporulation related domain 71 139 4.5E-7 T 13-09-2016 IPR007730 Sporulation-related domain GO:0042834 THL1_RS03430 d03146b2d0f5d21ab640c2e6e9e1cb6a 225 Gene3D G3DSA:3.30.70.1070 65 138 2.5E-7 T 13-09-2016 IPR007730 Sporulation-related domain GO:0042834 THL1_RS27755 fedd70808ccae625d200b46e9af28be7 182 Gene3D G3DSA:2.60.120.10 90 180 1.2E-20 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS27755 fedd70808ccae625d200b46e9af28be7 182 Gene3D G3DSA:1.10.260.40 2 69 4.7E-22 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS27755 fedd70808ccae625d200b46e9af28be7 182 PANTHER PTHR10245:SF42 1 182 5.4E-106 T 13-09-2016 THL1_RS27755 fedd70808ccae625d200b46e9af28be7 182 PANTHER PTHR10245 1 182 5.4E-106 T 13-09-2016 THL1_RS27755 fedd70808ccae625d200b46e9af28be7 182 Pfam PF01381 Helix-turn-helix 7 59 5.7E-14 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS27755 fedd70808ccae625d200b46e9af28be7 182 Pfam PF07883 Cupin domain 108 175 2.0E-19 T 13-09-2016 IPR013096 Cupin 2, conserved barrel THL1_RS27755 fedd70808ccae625d200b46e9af28be7 182 SUPERFAMILY SSF47413 3 66 1.74E-15 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS27755 fedd70808ccae625d200b46e9af28be7 182 SMART SM00530 6 61 1.6E-14 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS27755 fedd70808ccae625d200b46e9af28be7 182 SUPERFAMILY SSF51182 66 182 2.08E-26 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS18060 572b02d426c980a60471c719d04e16d8 158 PANTHER PTHR35175:SF2 1 76 5.0E-25 T 13-09-2016 THL1_RS18060 572b02d426c980a60471c719d04e16d8 158 PANTHER PTHR35175 1 76 5.0E-25 T 13-09-2016 THL1_RS18060 572b02d426c980a60471c719d04e16d8 158 Pfam PF06945 Protein of unknown function (DUF1289) 8 52 4.3E-15 T 13-09-2016 IPR010710 Protein of unknown function DUF1289 THL1_RS23185 484b6899648d18978582232f79247065 292 SUPERFAMILY SSF56317 2 277 1.44E-53 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS23185 484b6899648d18978582232f79247065 292 Pfam PF00795 Carbon-nitrogen hydrolase 3 213 1.7E-23 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS23185 484b6899648d18978582232f79247065 292 Gene3D G3DSA:3.60.110.10 1 281 1.4E-54 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS23185 484b6899648d18978582232f79247065 292 PANTHER PTHR23088 1 286 2.2E-81 T 13-09-2016 THL1_RS23185 484b6899648d18978582232f79247065 292 PANTHER PTHR23088:SF12 1 286 2.2E-81 T 13-09-2016 THL1_RS09280 b65a216f5dd3e9cb12b70112b95057ba 240 Gene3D G3DSA:3.40.225.10 6 217 7.6E-60 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS09280 b65a216f5dd3e9cb12b70112b95057ba 240 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 12 190 2.3E-45 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS09280 b65a216f5dd3e9cb12b70112b95057ba 240 SUPERFAMILY SSF53639 7 207 6.08E-57 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS09280 b65a216f5dd3e9cb12b70112b95057ba 240 PANTHER PTHR10672 3 194 4.5E-81 T 13-09-2016 THL1_RS09280 b65a216f5dd3e9cb12b70112b95057ba 240 SMART SM01007 11 190 9.0E-57 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS24480 64c5d3fe98e06b3d8a5c9fac70b641a1 267 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 150 167 - T 13-09-2016 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS24480 64c5d3fe98e06b3d8a5c9fac70b641a1 267 SUPERFAMILY SSF55347 127 236 8.72E-38 T 13-09-2016 THL1_RS24480 64c5d3fe98e06b3d8a5c9fac70b641a1 267 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 3 265 1.3E-102 T 13-09-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS24480 64c5d3fe98e06b3d8a5c9fac70b641a1 267 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 128 264 2.8E-43 T 13-09-2016 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS24480 64c5d3fe98e06b3d8a5c9fac70b641a1 267 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 2 265 36.157 T 13-09-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS24480 64c5d3fe98e06b3d8a5c9fac70b641a1 267 PANTHER PTHR20836:SF0 3 266 1.7E-100 T 13-09-2016 THL1_RS24480 64c5d3fe98e06b3d8a5c9fac70b641a1 267 Gene3D G3DSA:3.40.50.720 2 163 4.2E-61 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS24480 64c5d3fe98e06b3d8a5c9fac70b641a1 267 PANTHER PTHR20836 3 266 1.7E-100 T 13-09-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS24480 64c5d3fe98e06b3d8a5c9fac70b641a1 267 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 125 1.7E-43 T 13-09-2016 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS24480 64c5d3fe98e06b3d8a5c9fac70b641a1 267 SUPERFAMILY SSF51735 236 266 4.51E-53 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS24480 64c5d3fe98e06b3d8a5c9fac70b641a1 267 SUPERFAMILY SSF51735 1 126 4.51E-53 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS24480 64c5d3fe98e06b3d8a5c9fac70b641a1 267 PIRSF PIRSF000161 1 267 4.9E-91 T 13-09-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 THL1_RS11785 912a150b686297cb5029415a2789e6eb 83 Pfam PF11839 Alanine-zipper, major outer membrane lipoprotein 3 83 6.2E-11 T 13-09-2016 IPR021793 Major outer membrane lipoprotein Oprl THL1_RS07400 7b4d6a98a8553b2b0cc80e5381f6003f 254 SUPERFAMILY SSF52540 5 248 8.79E-80 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07400 7b4d6a98a8553b2b0cc80e5381f6003f 254 SMART SM00382 29 226 1.3E-15 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS07400 7b4d6a98a8553b2b0cc80e5381f6003f 254 PANTHER PTHR24220 6 252 9.4E-135 T 13-09-2016 THL1_RS07400 7b4d6a98a8553b2b0cc80e5381f6003f 254 Pfam PF00005 ABC transporter 20 178 2.8E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS07400 7b4d6a98a8553b2b0cc80e5381f6003f 254 PANTHER PTHR24220:SF327 6 252 9.4E-135 T 13-09-2016 THL1_RS07400 7b4d6a98a8553b2b0cc80e5381f6003f 254 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS07400 7b4d6a98a8553b2b0cc80e5381f6003f 254 PIRSF PIRSF039085 1 254 8.3E-119 T 13-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 THL1_RS07400 7b4d6a98a8553b2b0cc80e5381f6003f 254 Gene3D G3DSA:3.40.50.300 4 250 6.6E-82 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03205 db2cdba2c7b578f68b5f521d6b1ada6a 111 SUPERFAMILY SSF46626 35 103 9.3E-13 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS03205 db2cdba2c7b578f68b5f521d6b1ada6a 111 Gene3D G3DSA:1.10.760.10 36 107 4.4E-17 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS03205 db2cdba2c7b578f68b5f521d6b1ada6a 111 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 37 101 5.7E-15 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS26835 edf6e90820687bdeaaf9c4b65dc53e9a 250 Gene3D G3DSA:3.40.190.10 24 112 8.8E-47 T 13-09-2016 THL1_RS26835 edf6e90820687bdeaaf9c4b65dc53e9a 250 Gene3D G3DSA:3.40.190.10 208 249 8.8E-47 T 13-09-2016 THL1_RS26835 edf6e90820687bdeaaf9c4b65dc53e9a 250 PANTHER PTHR18966:SF152 22 246 3.8E-86 T 13-09-2016 THL1_RS26835 edf6e90820687bdeaaf9c4b65dc53e9a 250 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 27 245 8.7E-67 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS26835 edf6e90820687bdeaaf9c4b65dc53e9a 250 SUPERFAMILY SSF53850 5 249 6.72E-74 T 13-09-2016 THL1_RS26835 edf6e90820687bdeaaf9c4b65dc53e9a 250 SMART SM00062 26 248 3.1E-62 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS26835 edf6e90820687bdeaaf9c4b65dc53e9a 250 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 49 62 - T 13-09-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 THL1_RS26835 edf6e90820687bdeaaf9c4b65dc53e9a 250 PANTHER PTHR18966 22 246 3.8E-86 T 13-09-2016 THL1_RS26835 edf6e90820687bdeaaf9c4b65dc53e9a 250 Gene3D G3DSA:3.40.190.10 114 207 2.3E-23 T 13-09-2016 THL1_RS26600 3b5eef748e1f76e336ba52de0dccfc52 1196 PANTHER PTHR38434:SF1 18 569 3.2E-142 T 13-09-2016 THL1_RS26600 3b5eef748e1f76e336ba52de0dccfc52 1196 PANTHER PTHR38434:SF1 777 1196 3.2E-142 T 13-09-2016 THL1_RS26600 3b5eef748e1f76e336ba52de0dccfc52 1196 Pfam PF10101 Predicted membrane protein (DUF2339) 178 533 2.0E-109 T 13-09-2016 IPR019286 Protein of unknown function DUF2339, transmembrane THL1_RS26600 3b5eef748e1f76e336ba52de0dccfc52 1196 Pfam PF10101 Predicted membrane protein (DUF2339) 851 1183 7.4E-44 T 13-09-2016 IPR019286 Protein of unknown function DUF2339, transmembrane THL1_RS26600 3b5eef748e1f76e336ba52de0dccfc52 1196 PANTHER PTHR38434 777 1196 3.2E-142 T 13-09-2016 THL1_RS26600 3b5eef748e1f76e336ba52de0dccfc52 1196 PANTHER PTHR38434 18 569 3.2E-142 T 13-09-2016 THL1_RS27735 da5b9bf5b4dac1239bbd496a502e95c3 557 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 120 275 8.0E-24 T 13-09-2016 IPR000160 GGDEF domain THL1_RS27735 da5b9bf5b4dac1239bbd496a502e95c3 557 Pfam PF00990 Diguanylate cyclase, GGDEF domain 124 274 2.2E-31 T 13-09-2016 IPR000160 GGDEF domain THL1_RS27735 da5b9bf5b4dac1239bbd496a502e95c3 557 SUPERFAMILY SSF55073 129 284 2.04E-36 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS27735 da5b9bf5b4dac1239bbd496a502e95c3 557 SUPERFAMILY SSF141868 297 543 1.03E-86 T 13-09-2016 IPR001633 EAL domain THL1_RS27735 da5b9bf5b4dac1239bbd496a502e95c3 557 SMART SM00267 113 282 2.6E-37 T 13-09-2016 IPR000160 GGDEF domain THL1_RS27735 da5b9bf5b4dac1239bbd496a502e95c3 557 PANTHER PTHR33121:SF13 132 139 4.6E-81 T 13-09-2016 THL1_RS27735 da5b9bf5b4dac1239bbd496a502e95c3 557 SMART SM00052 292 538 9.3E-114 T 13-09-2016 IPR001633 EAL domain THL1_RS27735 da5b9bf5b4dac1239bbd496a502e95c3 557 PANTHER PTHR33121:SF13 245 543 4.6E-81 T 13-09-2016 THL1_RS27735 da5b9bf5b4dac1239bbd496a502e95c3 557 PANTHER PTHR33121 132 139 4.6E-81 T 13-09-2016 THL1_RS27735 da5b9bf5b4dac1239bbd496a502e95c3 557 Pfam PF00563 EAL domain 298 533 1.4E-73 T 13-09-2016 IPR001633 EAL domain THL1_RS27735 da5b9bf5b4dac1239bbd496a502e95c3 557 Gene3D G3DSA:3.30.70.270 126 289 1.5E-43 T 13-09-2016 THL1_RS27735 da5b9bf5b4dac1239bbd496a502e95c3 557 PANTHER PTHR33121 245 543 4.6E-81 T 13-09-2016 THL1_RS27735 da5b9bf5b4dac1239bbd496a502e95c3 557 Gene3D G3DSA:3.20.20.450 296 543 2.8E-96 T 13-09-2016 IPR001633 EAL domain THL1_RS05960 e40027baf4186fba3576b1f14504dc7b 66 SUPERFAMILY SSF140319 2 64 2.75E-25 T 13-09-2016 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 THL1_RS05960 e40027baf4186fba3576b1f14504dc7b 66 Gene3D G3DSA:1.10.10.600 1 66 1.2E-31 T 13-09-2016 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 THL1_RS05960 e40027baf4186fba3576b1f14504dc7b 66 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 4 66 6.7E-33 T 13-09-2016 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 THL1_RS05960 e40027baf4186fba3576b1f14504dc7b 66 PIRSF PIRSF039003 3 66 8.8E-33 T 13-09-2016 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 THL1_RS05960 e40027baf4186fba3576b1f14504dc7b 66 Pfam PF04384 Iron-sulphur cluster assembly 3 65 3.9E-30 T 13-09-2016 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 THL1_RS05960 e40027baf4186fba3576b1f14504dc7b 66 PANTHER PTHR37532 1 66 7.2E-30 T 13-09-2016 THL1_RS05210 03171b94ba87082260233f5d1344b822 324 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS05210 03171b94ba87082260233f5d1344b822 324 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 314 6.9E-21 T 13-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THL1_RS05210 03171b94ba87082260233f5d1344b822 324 Gene3D G3DSA:3.40.50.300 3 258 1.2E-75 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05210 03171b94ba87082260233f5d1344b822 324 PANTHER PTHR24220:SF576 5 324 3.0E-195 T 13-09-2016 THL1_RS05210 03171b94ba87082260233f5d1344b822 324 PANTHER PTHR24220 5 324 3.0E-195 T 13-09-2016 THL1_RS05210 03171b94ba87082260233f5d1344b822 324 SMART SM00382 31 230 4.0E-16 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS05210 03171b94ba87082260233f5d1344b822 324 SUPERFAMILY SSF52540 3 251 4.73E-66 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05210 03171b94ba87082260233f5d1344b822 324 Pfam PF00005 ABC transporter 23 180 1.6E-28 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS05210 03171b94ba87082260233f5d1344b822 324 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 296 6.7E-15 T 13-09-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THL1_RS26115 d821ee6b91af8a93fe217c01f38a44bb 367 SUPERFAMILY SSF53383 14 365 2.67E-104 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS26115 d821ee6b91af8a93fe217c01f38a44bb 367 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 15 361 6.2E-119 T 13-09-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THL1_RS26115 d821ee6b91af8a93fe217c01f38a44bb 367 Gene3D G3DSA:3.40.640.10 13 247 5.6E-76 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS26115 d821ee6b91af8a93fe217c01f38a44bb 367 PIRSF PIRSF000390 1 367 4.7E-101 T 13-09-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THL1_RS26115 d821ee6b91af8a93fe217c01f38a44bb 367 PANTHER PTHR30244:SF13 1 367 1.5E-139 T 13-09-2016 THL1_RS26115 d821ee6b91af8a93fe217c01f38a44bb 367 PANTHER PTHR30244 1 367 1.5E-139 T 13-09-2016 THL1_RS26115 d821ee6b91af8a93fe217c01f38a44bb 367 Gene3D G3DSA:3.90.1150.10 249 365 9.3E-39 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS22115 b5703bf983474b09170de99d582ccdeb 148 Gene3D G3DSA:3.10.129.10 8 139 3.2E-48 T 13-09-2016 IPR029069 HotDog domain THL1_RS22115 b5703bf983474b09170de99d582ccdeb 148 PANTHER PTHR31793:SF9 8 139 1.2E-47 T 13-09-2016 THL1_RS22115 b5703bf983474b09170de99d582ccdeb 148 Pfam PF03061 Thioesterase superfamily 24 105 7.1E-16 T 13-09-2016 IPR006683 Thioesterase domain THL1_RS22115 b5703bf983474b09170de99d582ccdeb 148 PANTHER PTHR31793 8 139 1.2E-47 T 13-09-2016 THL1_RS22115 b5703bf983474b09170de99d582ccdeb 148 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 10 135 2.9E-48 T 13-09-2016 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 KEGG: 00360+3.1.2.-|KEGG: 00362+3.1.2.-|KEGG: 00592+3.1.2.-|KEGG: 00903+3.1.2.- THL1_RS22115 b5703bf983474b09170de99d582ccdeb 148 SUPERFAMILY SSF54637 9 138 7.01E-41 T 13-09-2016 IPR029069 HotDog domain THL1_RS22115 b5703bf983474b09170de99d582ccdeb 148 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 13 130 1.5E-32 T 13-09-2016 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 THL1_RS22115 b5703bf983474b09170de99d582ccdeb 148 PIRSF PIRSF003230 2 141 7.7E-45 T 13-09-2016 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 THL1_RS08300 116352e316ace5f578473bba421a6d86 262 ProSitePatterns PS00622 LuxR-type HTH domain signature. 216 243 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS08300 116352e316ace5f578473bba421a6d86 262 SUPERFAMILY SSF46894 193 258 3.4E-18 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS08300 116352e316ace5f578473bba421a6d86 262 Pfam PF00196 Bacterial regulatory proteins, luxR family 201 254 7.9E-18 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS08300 116352e316ace5f578473bba421a6d86 262 PANTHER PTHR26402 175 258 9.7E-33 T 13-09-2016 THL1_RS08300 116352e316ace5f578473bba421a6d86 262 Gene3D G3DSA:1.10.10.10 201 259 7.9E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08300 116352e316ace5f578473bba421a6d86 262 SMART SM00421 199 256 1.6E-18 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS08300 116352e316ace5f578473bba421a6d86 262 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 202 216 1.7E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS08300 116352e316ace5f578473bba421a6d86 262 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 216 232 1.7E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS08300 116352e316ace5f578473bba421a6d86 262 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 232 244 1.7E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS08300 116352e316ace5f578473bba421a6d86 262 PANTHER PTHR26402:SF572 175 258 9.7E-33 T 13-09-2016 THL1_RS16155 2240b50253b095f76611535d9b39f759 114 PANTHER PTHR35862:SF2 1 107 7.0E-26 T 13-09-2016 THL1_RS16155 2240b50253b095f76611535d9b39f759 114 Gene3D G3DSA:3.10.450.40 3 111 3.3E-35 T 13-09-2016 THL1_RS16155 2240b50253b095f76611535d9b39f759 114 SUPERFAMILY SSF160719 6 110 3.92E-28 T 13-09-2016 THL1_RS16155 2240b50253b095f76611535d9b39f759 114 Pfam PF04965 Gene 25-like lysozyme 14 96 7.5E-16 T 13-09-2016 IPR007048 GpW/Gp25/anti-adapter protein IraD THL1_RS16155 2240b50253b095f76611535d9b39f759 114 PANTHER PTHR35862 1 107 7.0E-26 T 13-09-2016 THL1_RS17790 e875faf63a63fa7a2794dbb105d1a424 284 PANTHER PTHR11614:SF82 14 243 1.6E-34 T 13-09-2016 THL1_RS17790 e875faf63a63fa7a2794dbb105d1a424 284 SUPERFAMILY SSF53474 5 266 3.1E-28 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS17790 e875faf63a63fa7a2794dbb105d1a424 284 Gene3D G3DSA:3.40.50.1820 4 278 5.0E-25 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS17790 e875faf63a63fa7a2794dbb105d1a424 284 PANTHER PTHR11614 14 243 1.6E-34 T 13-09-2016 THL1_RS17790 e875faf63a63fa7a2794dbb105d1a424 284 PIRSF PIRSF037442 2 284 4.7E-97 T 13-09-2016 IPR017208 Uncharacterised conserved protein UCP037442, alpha/beta hydrolase, RSp0795 THL1_RS17790 e875faf63a63fa7a2794dbb105d1a424 284 Pfam PF12146 Serine aminopeptidase, S33 27 117 5.5E-13 T 13-09-2016 IPR022742 Serine aminopeptidase, S33 THL1_RS25520 3800d54253f3dd10e611311c49be0148 198 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 9 192 7.7E-37 T 13-09-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 THL1_RS25520 3800d54253f3dd10e611311c49be0148 198 PANTHER PTHR33508:SF1 1 194 2.5E-62 T 13-09-2016 THL1_RS25520 3800d54253f3dd10e611311c49be0148 198 PANTHER PTHR33508 1 194 2.5E-62 T 13-09-2016 THL1_RS25520 3800d54253f3dd10e611311c49be0148 198 Pfam PF01914 MarC family integral membrane protein 5 195 3.0E-39 T 13-09-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 THL1_RS25695 09d9507db7d14fbaad217162a7c391c7 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 29 45 1.3E-20 T 13-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THL1_RS25695 09d9507db7d14fbaad217162a7c391c7 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 51 67 1.3E-20 T 13-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THL1_RS25695 09d9507db7d14fbaad217162a7c391c7 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 70 88 1.3E-20 T 13-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THL1_RS25695 09d9507db7d14fbaad217162a7c391c7 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 334 349 1.3E-20 T 13-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THL1_RS25695 09d9507db7d14fbaad217162a7c391c7 373 PANTHER PTHR30483:SF20 4 373 2.7E-128 T 13-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THL1_RS25695 09d9507db7d14fbaad217162a7c391c7 373 SUPERFAMILY SSF53822 28 370 6.02E-89 T 13-09-2016 IPR028082 Periplasmic binding protein-like I THL1_RS25695 09d9507db7d14fbaad217162a7c391c7 373 Pfam PF13458 Periplasmic binding protein 29 368 2.6E-61 T 13-09-2016 IPR028081 Leucine-binding protein domain THL1_RS25695 09d9507db7d14fbaad217162a7c391c7 373 PANTHER PTHR30483 4 373 2.7E-128 T 13-09-2016 THL1_RS25695 09d9507db7d14fbaad217162a7c391c7 373 Gene3D G3DSA:3.40.50.2300 28 228 7.8E-69 T 13-09-2016 THL1_RS18110 539a788ad3b5c90d4efe999121c080eb 556 SUPERFAMILY SSF81606 4 229 4.71E-44 T 13-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 THL1_RS18110 539a788ad3b5c90d4efe999121c080eb 556 Pfam PF13672 Protein phosphatase 2C 17 183 3.5E-8 T 13-09-2016 THL1_RS18110 539a788ad3b5c90d4efe999121c080eb 556 SUPERFAMILY SSF56112 247 512 1.89E-47 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS18110 539a788ad3b5c90d4efe999121c080eb 556 Pfam PF00069 Protein kinase domain 271 460 9.3E-27 T 13-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THL1_RS18110 539a788ad3b5c90d4efe999121c080eb 556 PANTHER PTHR24348:SF23 304 512 8.7E-99 T 13-09-2016 THL1_RS18110 539a788ad3b5c90d4efe999121c080eb 556 SMART SM00331 22 228 4.3E-13 T 13-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 THL1_RS18110 539a788ad3b5c90d4efe999121c080eb 556 Gene3D G3DSA:1.10.510.10 338 520 6.2E-36 T 13-09-2016 THL1_RS18110 539a788ad3b5c90d4efe999121c080eb 556 Gene3D G3DSA:3.60.40.10 2 228 3.2E-45 T 13-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 THL1_RS18110 539a788ad3b5c90d4efe999121c080eb 556 PANTHER PTHR24348 304 512 8.7E-99 T 13-09-2016 THL1_RS18110 539a788ad3b5c90d4efe999121c080eb 556 SMART SM00220 261 508 5.6E-13 T 13-09-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 THL1_RS18110 539a788ad3b5c90d4efe999121c080eb 556 SMART SM00332 2 226 3.3E-6 T 13-09-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 THL1_RS23925 6d596faa58e0a87ef683cd9defec6e57 140 Gene3D G3DSA:3.10.450.50 12 135 8.0E-12 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS23925 6d596faa58e0a87ef683cd9defec6e57 140 Pfam PF12680 SnoaL-like domain 12 106 4.8E-12 T 13-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain THL1_RS23925 6d596faa58e0a87ef683cd9defec6e57 140 SUPERFAMILY SSF54427 7 116 3.59E-20 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS12205 2c8ef96c1f4d6dfd84b25a79aa73b249 198 SUPERFAMILY SSF52218 3 166 6.37E-26 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS12205 2c8ef96c1f4d6dfd84b25a79aa73b249 198 PANTHER PTHR30543 1 194 3.3E-28 T 13-09-2016 THL1_RS12205 2c8ef96c1f4d6dfd84b25a79aa73b249 198 PANTHER PTHR30543:SF1 1 194 3.3E-28 T 13-09-2016 THL1_RS12205 2c8ef96c1f4d6dfd84b25a79aa73b249 198 Pfam PF03358 NADPH-dependent FMN reductase 3 141 1.9E-19 T 13-09-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 THL1_RS12205 2c8ef96c1f4d6dfd84b25a79aa73b249 198 Gene3D G3DSA:3.40.50.360 3 182 1.8E-23 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS23250 d33df54fed9455a51d91f3b2c68ae3e9 256 SUPERFAMILY SSF55729 30 228 5.04E-36 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS23250 d33df54fed9455a51d91f3b2c68ae3e9 256 Gene3D G3DSA:3.40.630.30 30 223 4.0E-22 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS23250 d33df54fed9455a51d91f3b2c68ae3e9 256 PANTHER PTHR37323:SF1 1 256 9.3E-88 T 13-09-2016 THL1_RS23250 d33df54fed9455a51d91f3b2c68ae3e9 256 Pfam PF13444 Acetyltransferase (GNAT) domain 38 138 1.9E-26 T 13-09-2016 THL1_RS23250 d33df54fed9455a51d91f3b2c68ae3e9 256 PANTHER PTHR37323 1 256 9.3E-88 T 13-09-2016 THL1_RS06220 353add916686fc77ae2a36372cdbac57 290 Gene3D G3DSA:1.10.10.60 190 239 9.0E-19 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS06220 353add916686fc77ae2a36372cdbac57 290 PANTHER PTHR11019 51 290 2.1E-52 T 13-09-2016 THL1_RS06220 353add916686fc77ae2a36372cdbac57 290 SMART SM00342 203 286 4.0E-33 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS06220 353add916686fc77ae2a36372cdbac57 290 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 240 282 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS06220 353add916686fc77ae2a36372cdbac57 290 SUPERFAMILY SSF46689 190 236 1.93E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS06220 353add916686fc77ae2a36372cdbac57 290 Pfam PF12833 Helix-turn-helix domain 209 287 8.3E-24 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS06220 353add916686fc77ae2a36372cdbac57 290 Gene3D G3DSA:1.10.10.60 240 288 7.5E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS06220 353add916686fc77ae2a36372cdbac57 290 PANTHER PTHR11019:SF105 51 290 2.1E-52 T 13-09-2016 THL1_RS06220 353add916686fc77ae2a36372cdbac57 290 SUPERFAMILY SSF46689 239 288 2.28E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS10010 732d4d904e032a64c0c9d3a69770f8b5 295 SUPERFAMILY SSF46785 1 110 1.03E-26 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS10010 732d4d904e032a64c0c9d3a69770f8b5 295 Pfam PF03466 LysR substrate binding domain 87 287 7.7E-44 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS10010 732d4d904e032a64c0c9d3a69770f8b5 295 Gene3D G3DSA:3.40.190.10 181 257 1.5E-19 T 13-09-2016 THL1_RS10010 732d4d904e032a64c0c9d3a69770f8b5 295 SUPERFAMILY SSF53850 88 292 2.93E-41 T 13-09-2016 THL1_RS10010 732d4d904e032a64c0c9d3a69770f8b5 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.3E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS10010 732d4d904e032a64c0c9d3a69770f8b5 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.3E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS10010 732d4d904e032a64c0c9d3a69770f8b5 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.3E-10 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS10010 732d4d904e032a64c0c9d3a69770f8b5 295 Gene3D G3DSA:3.40.190.10 89 180 4.7E-19 T 13-09-2016 THL1_RS10010 732d4d904e032a64c0c9d3a69770f8b5 295 PANTHER PTHR30126 1 286 2.5E-173 T 13-09-2016 THL1_RS10010 732d4d904e032a64c0c9d3a69770f8b5 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.1E-22 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS10010 732d4d904e032a64c0c9d3a69770f8b5 295 PANTHER PTHR30126:SF33 1 286 2.5E-173 T 13-09-2016 THL1_RS10010 732d4d904e032a64c0c9d3a69770f8b5 295 Gene3D G3DSA:1.10.10.10 1 86 4.5E-30 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS22825 b4ed471a37c3b16d77c504e0c9a9693e 878 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 135 148 8.9E-68 T 13-09-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THL1_RS22825 b4ed471a37c3b16d77c504e0c9a9693e 878 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 188 204 8.9E-68 T 13-09-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THL1_RS22825 b4ed471a37c3b16d77c504e0c9a9693e 878 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 247 262 8.9E-68 T 13-09-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THL1_RS22825 b4ed471a37c3b16d77c504e0c9a9693e 878 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 707 733 8.9E-68 T 13-09-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THL1_RS22825 b4ed471a37c3b16d77c504e0c9a9693e 878 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 534 554 8.9E-68 T 13-09-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THL1_RS22825 b4ed471a37c3b16d77c504e0c9a9693e 878 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 385 405 8.9E-68 T 13-09-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THL1_RS22825 b4ed471a37c3b16d77c504e0c9a9693e 878 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 576 605 8.9E-68 T 13-09-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THL1_RS22825 b4ed471a37c3b16d77c504e0c9a9693e 878 Gene3D G3DSA:1.20.1440.90 275 388 2.7E-33 T 13-09-2016 THL1_RS22825 b4ed471a37c3b16d77c504e0c9a9693e 878 PANTHER PTHR30523 1 878 0.0 T 13-09-2016 THL1_RS22825 b4ed471a37c3b16d77c504e0c9a9693e 878 PANTHER PTHR30523:SF3 1 878 0.0 T 13-09-2016 THL1_RS22825 b4ed471a37c3b16d77c504e0c9a9693e 878 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 536 548 - T 13-09-2016 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THL1_RS22825 b4ed471a37c3b16d77c504e0c9a9693e 878 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 1 878 18.606 T 13-09-2016 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THL1_RS22825 b4ed471a37c3b16d77c504e0c9a9693e 878 SUPERFAMILY SSF51621 5 878 0.0 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS22825 b4ed471a37c3b16d77c504e0c9a9693e 878 Pfam PF00311 Phosphoenolpyruvate carboxylase 131 878 8.5E-274 T 13-09-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THL1_RS22825 b4ed471a37c3b16d77c504e0c9a9693e 878 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 136 147 - T 13-09-2016 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 TIGRFAM TIGR02963 xanthine_xdhA: xanthine dehydrogenase, small subunit 2 465 6.6E-211 T 13-09-2016 IPR014307 Xanthine dehydrogenase, small subunit GO:0004854|GO:0004855|GO:0050660|GO:0055114 KEGG: 00230+1.17.1.4|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 SUPERFAMILY SSF56176 181 357 8.83E-54 T 13-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 SMART SM01092 365 466 1.3E-34 T 13-09-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 194 357 4.0E-51 T 13-09-2016 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 SUPERFAMILY SSF54292 2 85 2.49E-17 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 Gene3D G3DSA:3.10.20.30 2 81 3.1E-25 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 PIRSF PIRSF036557 1 479 1.7E-214 T 13-09-2016 IPR012175 Xanthine dehydrogenase, small subunit, bacteria THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 SUPERFAMILY SSF47741 92 196 3.4E-33 T 13-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 17 71 1.6E-5 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 39 47 - T 13-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 Gene3D G3DSA:1.10.150.120 82 178 2.3E-36 T 13-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 Gene3D G3DSA:3.30.390.50 366 467 1.4E-38 T 13-09-2016 THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 365 465 4.2E-33 T 13-09-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 Gene3D G3DSA:3.30.465.10 245 356 4.2E-37 T 13-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 SUPERFAMILY SSF55447 361 467 1.83E-36 T 13-09-2016 IPR005107 CO dehydrogenase flavoprotein, C-terminal THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 Gene3D G3DSA:3.30.43.10 196 243 8.7E-22 T 13-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 Pfam PF01799 [2Fe-2S] binding domain 81 153 1.1E-29 T 13-09-2016 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 THL1_RS09525 b188b0ab814ba739113abb9b2c63143b 479 PANTHER PTHR11908 2 466 7.4E-137 T 13-09-2016 THL1_RS08380 f565cd9482664583896fb37aba237e7b 101 SUPERFAMILY SSF103481 5 100 2.22E-19 T 13-09-2016 THL1_RS08380 f565cd9482664583896fb37aba237e7b 101 PANTHER PTHR30561 1 101 1.7E-38 T 13-09-2016 THL1_RS08380 f565cd9482664583896fb37aba237e7b 101 Pfam PF00893 Small Multidrug Resistance protein 1 93 8.6E-25 T 13-09-2016 IPR000390 Small multidrug resistance protein family GO:0016021 THL1_RS08380 f565cd9482664583896fb37aba237e7b 101 PANTHER PTHR30561:SF0 1 101 1.7E-38 T 13-09-2016 THL1_RS22415 647e101896c6294810ebe7088d566f58 259 PANTHER PTHR19370:SF98 5 258 7.5E-128 T 13-09-2016 THL1_RS22415 647e101896c6294810ebe7088d566f58 259 Gene3D G3DSA:2.40.30.10 6 98 1.9E-30 T 13-09-2016 THL1_RS22415 647e101896c6294810ebe7088d566f58 259 SUPERFAMILY SSF63380 6 100 2.33E-24 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS22415 647e101896c6294810ebe7088d566f58 259 Pfam PF00970 Oxidoreductase FAD-binding domain 17 99 4.7E-8 T 13-09-2016 IPR008333 Oxidoreductase, FAD-binding domain THL1_RS22415 647e101896c6294810ebe7088d566f58 259 PANTHER PTHR19370 5 258 7.5E-128 T 13-09-2016 THL1_RS22415 647e101896c6294810ebe7088d566f58 259 Pfam PF00175 Oxidoreductase NAD-binding domain 113 229 8.6E-10 T 13-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THL1_RS22415 647e101896c6294810ebe7088d566f58 259 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 137 146 6.2E-7 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS22415 647e101896c6294810ebe7088d566f58 259 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 52 59 6.2E-7 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS22415 647e101896c6294810ebe7088d566f58 259 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 112 131 6.2E-7 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS22415 647e101896c6294810ebe7088d566f58 259 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 216 224 6.2E-7 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS22415 647e101896c6294810ebe7088d566f58 259 SUPERFAMILY SSF52343 103 257 1.7E-45 T 13-09-2016 THL1_RS22415 647e101896c6294810ebe7088d566f58 259 Gene3D G3DSA:3.40.50.80 99 258 1.1E-50 T 13-09-2016 THL1_RS15595 bc7bd168a7ed45b44b6fb591c4e89c2d 375 PANTHER PTHR10909 4 375 2.4E-175 T 13-09-2016 THL1_RS15595 bc7bd168a7ed45b44b6fb591c4e89c2d 375 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 116 4.0E-37 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS15595 bc7bd168a7ed45b44b6fb591c4e89c2d 375 Gene3D G3DSA:1.20.140.10 216 375 4.1E-71 T 13-09-2016 THL1_RS15595 bc7bd168a7ed45b44b6fb591c4e89c2d 375 PANTHER PTHR10909:SF10 4 375 2.4E-175 T 13-09-2016 THL1_RS15595 bc7bd168a7ed45b44b6fb591c4e89c2d 375 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 375 8.2E-52 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS15595 bc7bd168a7ed45b44b6fb591c4e89c2d 375 SUPERFAMILY SSF47203 225 375 1.77E-58 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS15595 bc7bd168a7ed45b44b6fb591c4e89c2d 375 PIRSF PIRSF016578 3 375 1.4E-23 T 13-09-2016 THL1_RS15595 bc7bd168a7ed45b44b6fb591c4e89c2d 375 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 215 1.4E-27 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS15595 bc7bd168a7ed45b44b6fb591c4e89c2d 375 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS15595 bc7bd168a7ed45b44b6fb591c4e89c2d 375 SUPERFAMILY SSF56645 4 240 8.64E-87 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS15595 bc7bd168a7ed45b44b6fb591c4e89c2d 375 Gene3D G3DSA:2.40.110.10 119 215 5.7E-42 T 13-09-2016 THL1_RS15595 bc7bd168a7ed45b44b6fb591c4e89c2d 375 Gene3D G3DSA:1.10.540.10 4 118 2.1E-41 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS15150 1d70d606c14708499b794b020d6e88c1 269 Gene3D G3DSA:3.40.50.300 3 87 3.4E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15150 1d70d606c14708499b794b020d6e88c1 269 Pfam PF05707 Zonular occludens toxin (Zot) 4 85 3.3E-12 T 13-09-2016 IPR008900 Zona occludens toxin THL1_RS15280 1d70d606c14708499b794b020d6e88c1 269 Gene3D G3DSA:3.40.50.300 3 87 3.4E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15280 1d70d606c14708499b794b020d6e88c1 269 Pfam PF05707 Zonular occludens toxin (Zot) 4 85 3.3E-12 T 13-09-2016 IPR008900 Zona occludens toxin THL1_RS15180 1d70d606c14708499b794b020d6e88c1 269 Gene3D G3DSA:3.40.50.300 3 87 3.4E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15180 1d70d606c14708499b794b020d6e88c1 269 Pfam PF05707 Zonular occludens toxin (Zot) 4 85 3.3E-12 T 13-09-2016 IPR008900 Zona occludens toxin THL1_RS13540 23ae4850ba7e1e1054b1c2631bb6b191 196 Gene3D G3DSA:1.10.10.60 19 61 8.2E-19 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13540 23ae4850ba7e1e1054b1c2631bb6b191 196 Gene3D G3DSA:1.10.357.10 62 176 8.3E-14 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS13540 23ae4850ba7e1e1054b1c2631bb6b191 196 PANTHER PTHR30055 19 140 2.9E-16 T 13-09-2016 THL1_RS13540 23ae4850ba7e1e1054b1c2631bb6b191 196 SUPERFAMILY SSF46689 18 82 3.33E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13540 23ae4850ba7e1e1054b1c2631bb6b191 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 8.3E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS13540 23ae4850ba7e1e1054b1c2631bb6b191 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 8.3E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS13540 23ae4850ba7e1e1054b1c2631bb6b191 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 60 5.3E-14 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS23205 ce50f289cbfcca69af50b6a2a4662c06 193 PANTHER PTHR11019 112 145 6.4E-56 T 13-09-2016 THL1_RS23205 ce50f289cbfcca69af50b6a2a4662c06 193 Pfam PF01965 DJ-1/PfpI family 4 185 3.9E-49 T 13-09-2016 IPR002818 DJ-1/PfpI THL1_RS23205 ce50f289cbfcca69af50b6a2a4662c06 193 SUPERFAMILY SSF52317 4 188 2.72E-51 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS23205 ce50f289cbfcca69af50b6a2a4662c06 193 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 5 188 1.8E-53 T 13-09-2016 IPR006286 Peptidase C56, PfpI GO:0016798 THL1_RS23205 ce50f289cbfcca69af50b6a2a4662c06 193 PANTHER PTHR11019 4 94 6.4E-56 T 13-09-2016 THL1_RS23205 ce50f289cbfcca69af50b6a2a4662c06 193 PANTHER PTHR11019:SF112 4 94 6.4E-56 T 13-09-2016 THL1_RS23205 ce50f289cbfcca69af50b6a2a4662c06 193 PANTHER PTHR11019:SF112 112 145 6.4E-56 T 13-09-2016 THL1_RS23205 ce50f289cbfcca69af50b6a2a4662c06 193 Gene3D G3DSA:3.40.50.880 3 187 3.6E-57 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS19105 5ffc1bb3594523013771c0c5295b445c 76 Gene3D G3DSA:1.10.720.30 13 70 9.7E-33 T 13-09-2016 IPR003034 SAP domain THL1_RS19105 5ffc1bb3594523013771c0c5295b445c 76 Pfam PF09905 Uncharacterized conserved protein (DUF2132) 5 67 2.5E-35 T 13-09-2016 IPR018668 DNA-binding protein VF530-like, bacteria GO:0003677 THL1_RS18165 64fc5571398660e802e793504486c365 272 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 2 271 77.899 T 13-09-2016 IPR026530 Phosphoenolpyruvate synthase regulatory protein THL1_RS18165 64fc5571398660e802e793504486c365 272 PANTHER PTHR31756 1 272 1.4E-110 T 13-09-2016 THL1_RS18165 64fc5571398660e802e793504486c365 272 Pfam PF03618 Kinase/pyrophosphorylase 6 262 6.9E-78 T 13-09-2016 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 THL1_RS18165 64fc5571398660e802e793504486c365 272 PANTHER PTHR31756:SF3 1 272 1.4E-110 T 13-09-2016 THL1_RS21230 15af38608cb2e9b4f46071cb92ce44b4 260 Gene3D G3DSA:3.40.190.10 119 213 3.6E-25 T 13-09-2016 THL1_RS21230 15af38608cb2e9b4f46071cb92ce44b4 260 Gene3D G3DSA:3.40.190.10 25 113 3.1E-45 T 13-09-2016 THL1_RS21230 15af38608cb2e9b4f46071cb92ce44b4 260 Gene3D G3DSA:3.40.190.10 215 257 3.1E-45 T 13-09-2016 THL1_RS21230 15af38608cb2e9b4f46071cb92ce44b4 260 PANTHER PTHR18966:SF152 10 253 7.5E-66 T 13-09-2016 THL1_RS21230 15af38608cb2e9b4f46071cb92ce44b4 260 TIGRFAM TIGR01096 3A0103s03R: lysine-arginine-ornithine-binding periplasmic protein 6 253 1.8E-83 T 13-09-2016 IPR005768 Lysine-arginine-ornithine-binding periplasmic protein GO:0005215|GO:0006810|GO:0030288 THL1_RS21230 15af38608cb2e9b4f46071cb92ce44b4 260 PANTHER PTHR18966 10 253 7.5E-66 T 13-09-2016 THL1_RS21230 15af38608cb2e9b4f46071cb92ce44b4 260 SUPERFAMILY SSF53850 1 257 5.0E-69 T 13-09-2016 THL1_RS21230 15af38608cb2e9b4f46071cb92ce44b4 260 SMART SM00062 27 256 1.7E-68 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS21230 15af38608cb2e9b4f46071cb92ce44b4 260 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 254 6.3E-62 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS20570 f57005853c687e37d0e2bec79da25f0f 172 Gene3D G3DSA:3.10.450.50 11 142 1.7E-27 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS20570 f57005853c687e37d0e2bec79da25f0f 172 SUPERFAMILY SSF54427 7 140 7.11E-29 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS20570 f57005853c687e37d0e2bec79da25f0f 172 Pfam PF13577 SnoaL-like domain 10 130 8.4E-20 T 13-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain THL1_RS12885 9b716403bdb7494ebf32d9c0f6a31284 476 SUPERFAMILY SSF49503 165 308 5.38E-43 T 13-09-2016 IPR008972 Cupredoxin THL1_RS12885 9b716403bdb7494ebf32d9c0f6a31284 476 SUPERFAMILY SSF49503 108 134 5.38E-43 T 13-09-2016 IPR008972 Cupredoxin THL1_RS12885 9b716403bdb7494ebf32d9c0f6a31284 476 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 188 236 - T 13-09-2016 IPR001505 Copper centre Cu(A) GO:0005507 THL1_RS12885 9b716403bdb7494ebf32d9c0f6a31284 476 SUPERFAMILY SSF46626 265 365 7.09E-14 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS12885 9b716403bdb7494ebf32d9c0f6a31284 476 Pfam PF00034 Cytochrome c 275 364 6.5E-6 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS12885 9b716403bdb7494ebf32d9c0f6a31284 476 Pfam PF00034 Cytochrome c 374 464 6.6E-7 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS12885 9b716403bdb7494ebf32d9c0f6a31284 476 PANTHER PTHR22888 1 295 3.3E-72 T 13-09-2016 THL1_RS12885 9b716403bdb7494ebf32d9c0f6a31284 476 SUPERFAMILY SSF46626 374 463 7.16E-16 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS12885 9b716403bdb7494ebf32d9c0f6a31284 476 Gene3D G3DSA:1.10.760.10 373 463 1.2E-20 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS12885 9b716403bdb7494ebf32d9c0f6a31284 476 Gene3D G3DSA:1.10.760.10 272 364 4.9E-17 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS12885 9b716403bdb7494ebf32d9c0f6a31284 476 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 119 236 5.5E-14 T 13-09-2016 IPR002429 Cytochrome c oxidase subunit II C-terminal GO:0004129|GO:0005507|GO:0016020 THL1_RS12885 9b716403bdb7494ebf32d9c0f6a31284 476 PANTHER PTHR22888:SF2 1 295 3.3E-72 T 13-09-2016 THL1_RS12885 9b716403bdb7494ebf32d9c0f6a31284 476 PRINTS PR01166 Cytochrome c oxidase subunit II signature 187 207 8.9E-11 T 13-09-2016 THL1_RS12885 9b716403bdb7494ebf32d9c0f6a31284 476 PRINTS PR01166 Cytochrome c oxidase subunit II signature 225 242 8.9E-11 T 13-09-2016 THL1_RS12885 9b716403bdb7494ebf32d9c0f6a31284 476 PRINTS PR01166 Cytochrome c oxidase subunit II signature 111 130 8.9E-11 T 13-09-2016 THL1_RS12885 9b716403bdb7494ebf32d9c0f6a31284 476 PRINTS PR01166 Cytochrome c oxidase subunit II signature 163 184 8.9E-11 T 13-09-2016 THL1_RS12885 9b716403bdb7494ebf32d9c0f6a31284 476 Gene3D G3DSA:2.60.40.420 114 255 3.3E-34 T 13-09-2016 IPR008972 Cupredoxin THL1_RS24240 4a073c39984e9542bf2353f8b3994569 255 SMART SM00382 26 214 8.1E-16 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS24240 4a073c39984e9542bf2353f8b3994569 255 SUPERFAMILY SSF52540 2 227 2.77E-56 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24240 4a073c39984e9542bf2353f8b3994569 255 PANTHER PTHR24220:SF558 3 253 2.8E-91 T 13-09-2016 THL1_RS24240 4a073c39984e9542bf2353f8b3994569 255 Pfam PF00005 ABC transporter 17 167 1.6E-27 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS24240 4a073c39984e9542bf2353f8b3994569 255 PANTHER PTHR24220 3 253 2.8E-91 T 13-09-2016 THL1_RS24240 4a073c39984e9542bf2353f8b3994569 255 Gene3D G3DSA:3.40.50.300 1 230 1.4E-57 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25045 c4e1270d5c69b885705b474e78a037ed 217 PANTHER PTHR34300 1 210 6.0E-118 T 13-09-2016 THL1_RS25045 c4e1270d5c69b885705b474e78a037ed 217 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 13 201 3.7E-59 T 13-09-2016 IPR003744 Protein of unknown function DUF165 THL1_RS25045 c4e1270d5c69b885705b474e78a037ed 217 PANTHER PTHR34300:SF1 1 210 6.0E-118 T 13-09-2016 THL1_RS25045 c4e1270d5c69b885705b474e78a037ed 217 Pfam PF02592 Putative vitamin uptake transporter 43 199 5.2E-36 T 13-09-2016 IPR003744 Protein of unknown function DUF165 THL1_RS26450 46ba52b58e0218e4324eeabaaf9d5e9f 154 Pfam PF02416 mttA/Hcf106 family 4 40 7.0E-8 T 13-09-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 THL1_RS26450 46ba52b58e0218e4324eeabaaf9d5e9f 154 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 73 5.8E-23 T 13-09-2016 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 THL1_RS26450 46ba52b58e0218e4324eeabaaf9d5e9f 154 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 147 16.793 T 13-09-2016 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 THL1_RS26450 46ba52b58e0218e4324eeabaaf9d5e9f 154 PANTHER PTHR33162:SF4 1 139 8.3E-23 T 13-09-2016 THL1_RS26450 46ba52b58e0218e4324eeabaaf9d5e9f 154 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 9.5E-18 T 13-09-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 THL1_RS26450 46ba52b58e0218e4324eeabaaf9d5e9f 154 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 9.5E-18 T 13-09-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 THL1_RS26450 46ba52b58e0218e4324eeabaaf9d5e9f 154 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 9.5E-18 T 13-09-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 THL1_RS26450 46ba52b58e0218e4324eeabaaf9d5e9f 154 PANTHER PTHR33162 1 139 8.3E-23 T 13-09-2016 THL1_RS09680 12039e470d816ddfc03548124069acdf 173 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 21 160 3.1E-16 T 13-09-2016 IPR009936 Protein of unknown function DUF1468 THL1_RS26165 0e39799a7df509ff20469332e923b443 373 PANTHER PTHR12526:SF220 1 55 1.0E-101 T 13-09-2016 THL1_RS26165 0e39799a7df509ff20469332e923b443 373 PANTHER PTHR12526 1 55 1.0E-101 T 13-09-2016 THL1_RS26165 0e39799a7df509ff20469332e923b443 373 Gene3D G3DSA:3.40.50.2000 155 347 4.5E-18 T 13-09-2016 THL1_RS26165 0e39799a7df509ff20469332e923b443 373 SUPERFAMILY SSF53756 4 363 9.42E-56 T 13-09-2016 THL1_RS26165 0e39799a7df509ff20469332e923b443 373 PANTHER PTHR12526:SF220 79 352 1.0E-101 T 13-09-2016 THL1_RS26165 0e39799a7df509ff20469332e923b443 373 PANTHER PTHR12526 79 352 1.0E-101 T 13-09-2016 THL1_RS26165 0e39799a7df509ff20469332e923b443 373 Pfam PF00534 Glycosyl transferases group 1 185 348 2.1E-30 T 13-09-2016 IPR001296 Glycosyl transferase, family 1 THL1_RS25875 c7e775a539cc0627c5d17379d19231eb 474 Pfam PF11741 AMIN domain 30 129 4.8E-24 T 13-09-2016 IPR021731 AMIN domain THL1_RS25875 c7e775a539cc0627c5d17379d19231eb 474 PANTHER PTHR30404 1 428 1.2E-113 T 13-09-2016 THL1_RS25875 c7e775a539cc0627c5d17379d19231eb 474 Gene3D G3DSA:3.10.350.10 422 467 3.7E-15 T 13-09-2016 IPR018392 LysM domain THL1_RS25875 c7e775a539cc0627c5d17379d19231eb 474 Pfam PF01476 LysM domain 424 466 1.1E-10 T 13-09-2016 IPR018392 LysM domain THL1_RS25875 c7e775a539cc0627c5d17379d19231eb 474 SMART SM00257 423 466 8.3E-13 T 13-09-2016 IPR018392 LysM domain THL1_RS25875 c7e775a539cc0627c5d17379d19231eb 474 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 177 395 3.5E-46 T 13-09-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 THL1_RS25875 c7e775a539cc0627c5d17379d19231eb 474 SUPERFAMILY SSF53187 322 399 3.01E-53 T 13-09-2016 THL1_RS25875 c7e775a539cc0627c5d17379d19231eb 474 SUPERFAMILY SSF53187 175 271 3.01E-53 T 13-09-2016 THL1_RS25875 c7e775a539cc0627c5d17379d19231eb 474 Gene3D G3DSA:3.40.630.40 175 272 9.5E-59 T 13-09-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 THL1_RS25875 c7e775a539cc0627c5d17379d19231eb 474 Gene3D G3DSA:3.40.630.40 323 399 9.5E-59 T 13-09-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 THL1_RS25875 c7e775a539cc0627c5d17379d19231eb 474 SUPERFAMILY SSF54106 423 466 6.8E-10 T 13-09-2016 IPR018392 LysM domain THL1_RS25875 c7e775a539cc0627c5d17379d19231eb 474 PANTHER PTHR30404:SF1 1 428 1.2E-113 T 13-09-2016 THL1_RS25875 c7e775a539cc0627c5d17379d19231eb 474 SMART SM00646 237 395 3.2E-69 T 13-09-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 THL1_RS01185 354c59170d5176f818d43827c2f326d4 495 Pfam PF00675 Insulinase (Peptidase family M16) 76 219 2.4E-5 T 13-09-2016 IPR011765 Peptidase M16, N-terminal THL1_RS01185 354c59170d5176f818d43827c2f326d4 495 PANTHER PTHR11851:SF140 71 467 5.1E-65 T 13-09-2016 THL1_RS01185 354c59170d5176f818d43827c2f326d4 495 Gene3D G3DSA:3.30.830.10 64 277 2.5E-38 T 13-09-2016 IPR011237 Peptidase M16 domain GO:0046872 THL1_RS01185 354c59170d5176f818d43827c2f326d4 495 PANTHER PTHR11851 71 467 5.1E-65 T 13-09-2016 THL1_RS01185 354c59170d5176f818d43827c2f326d4 495 Gene3D G3DSA:3.30.830.10 296 471 4.4E-29 T 13-09-2016 IPR011237 Peptidase M16 domain GO:0046872 THL1_RS01185 354c59170d5176f818d43827c2f326d4 495 SUPERFAMILY SSF63411 63 268 4.17E-41 T 13-09-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THL1_RS01185 354c59170d5176f818d43827c2f326d4 495 SUPERFAMILY SSF63411 293 478 7.5E-46 T 13-09-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THL1_RS01185 354c59170d5176f818d43827c2f326d4 495 Pfam PF05193 Peptidase M16 inactive domain 230 405 3.6E-29 T 13-09-2016 IPR007863 Peptidase M16, C-terminal THL1_RS04590 a9f386fe11f37cf242edad7eecab1f1a 111 Pfam PF04480 Protein of unknown function (DUF559) 2 108 3.4E-43 T 13-09-2016 IPR007569 Domain of unknown function DUF559 THL1_RS04590 a9f386fe11f37cf242edad7eecab1f1a 111 PANTHER PTHR38590 2 109 9.4E-44 T 13-09-2016 THL1_RS04590 a9f386fe11f37cf242edad7eecab1f1a 111 PANTHER PTHR38590:SF1 2 109 9.4E-44 T 13-09-2016 THL1_RS04590 a9f386fe11f37cf242edad7eecab1f1a 111 SUPERFAMILY SSF52980 5 109 9.65E-21 T 13-09-2016 IPR011335 Restriction endonuclease type II-like THL1_RS04590 a9f386fe11f37cf242edad7eecab1f1a 111 Gene3D G3DSA:3.40.960.10 66 106 7.6E-5 T 13-09-2016 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 THL1_RS11245 606604d8d3decd1635d6202987f61e65 302 SUPERFAMILY SSF56601 1 302 3.5E-111 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS11245 606604d8d3decd1635d6202987f61e65 302 TIGRFAM TIGR03814 Gln_ase: glutaminase A 5 302 3.8E-129 T 13-09-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: REACT_13|Reactome: REACT_13685 THL1_RS11245 606604d8d3decd1635d6202987f61e65 302 Gene3D G3DSA:3.40.710.10 1 302 6.7E-123 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS11245 606604d8d3decd1635d6202987f61e65 302 PANTHER PTHR12544 1 302 7.9E-147 T 13-09-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: REACT_13|Reactome: REACT_13685 THL1_RS11245 606604d8d3decd1635d6202987f61e65 302 Hamap MF_00313 Glutaminase [glsA]. 1 302 47.075 T 13-09-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: REACT_13|Reactome: REACT_13685 THL1_RS11245 606604d8d3decd1635d6202987f61e65 302 Pfam PF04960 Glutaminase 19 302 2.9E-111 T 13-09-2016 IPR015868 Glutaminase GO:0004359|GO:0006541 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|Reactome: REACT_13|Reactome: REACT_13685 THL1_RS23135 2d8d87140a92e970ca57ef7f3a145c5f 167 SUPERFAMILY SSF141523 31 166 2.09E-23 T 13-09-2016 THL1_RS23135 2d8d87140a92e970ca57ef7f3a145c5f 167 Gene3D G3DSA:2.40.440.10 30 166 5.3E-20 T 13-09-2016 THL1_RS23135 2d8d87140a92e970ca57ef7f3a145c5f 167 PANTHER PTHR36699 1 167 9.9E-62 T 13-09-2016 THL1_RS23135 2d8d87140a92e970ca57ef7f3a145c5f 167 Pfam PF03734 L,D-transpeptidase catalytic domain 32 165 1.6E-18 T 13-09-2016 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 UniPathway: UPA00219 THL1_RS08275 2ecc2aaa6b3f17710622c1929277f8c1 502 Pfam PF02321 Outer membrane efflux protein 296 474 2.4E-23 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS08275 2ecc2aaa6b3f17710622c1929277f8c1 502 Pfam PF02321 Outer membrane efflux protein 71 263 2.9E-19 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS08275 2ecc2aaa6b3f17710622c1929277f8c1 502 SUPERFAMILY SSF56954 11 33 1.44E-92 T 13-09-2016 THL1_RS08275 2ecc2aaa6b3f17710622c1929277f8c1 502 SUPERFAMILY SSF56954 62 477 1.44E-92 T 13-09-2016 THL1_RS08275 2ecc2aaa6b3f17710622c1929277f8c1 502 PANTHER PTHR30203 9 495 1.0E-134 T 13-09-2016 THL1_RS08275 2ecc2aaa6b3f17710622c1929277f8c1 502 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 19 476 5.2E-104 T 13-09-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 THL1_RS08275 2ecc2aaa6b3f17710622c1929277f8c1 502 Gene3D G3DSA:2.20.200.10 324 361 6.0E-14 T 13-09-2016 THL1_RS08275 2ecc2aaa6b3f17710622c1929277f8c1 502 Gene3D G3DSA:2.20.200.10 108 150 6.0E-14 T 13-09-2016 THL1_RS08275 2ecc2aaa6b3f17710622c1929277f8c1 502 Gene3D G3DSA:1.20.1600.10 151 323 8.5E-86 T 13-09-2016 THL1_RS08275 2ecc2aaa6b3f17710622c1929277f8c1 502 Gene3D G3DSA:1.20.1600.10 57 97 8.5E-86 T 13-09-2016 THL1_RS08275 2ecc2aaa6b3f17710622c1929277f8c1 502 Gene3D G3DSA:1.20.1600.10 363 476 8.5E-86 T 13-09-2016 THL1_RS08275 2ecc2aaa6b3f17710622c1929277f8c1 502 PANTHER PTHR30203:SF3 9 495 1.0E-134 T 13-09-2016 THL1_RS02255 e561adf6ca15ed70308a233a5fe58d90 302 PANTHER PTHR30537 1 301 2.3E-160 T 13-09-2016 THL1_RS02255 e561adf6ca15ed70308a233a5fe58d90 302 Gene3D G3DSA:3.40.190.10 93 178 3.2E-26 T 13-09-2016 THL1_RS02255 e561adf6ca15ed70308a233a5fe58d90 302 Pfam PF03466 LysR substrate binding domain 89 293 1.9E-43 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS02255 e561adf6ca15ed70308a233a5fe58d90 302 SUPERFAMILY SSF53850 90 296 3.44E-43 T 13-09-2016 THL1_RS02255 e561adf6ca15ed70308a233a5fe58d90 302 PANTHER PTHR30537:SF20 1 301 2.3E-160 T 13-09-2016 THL1_RS02255 e561adf6ca15ed70308a233a5fe58d90 302 Gene3D G3DSA:1.10.10.10 2 84 1.8E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02255 e561adf6ca15ed70308a233a5fe58d90 302 Gene3D G3DSA:3.40.190.10 179 259 2.4E-5 T 13-09-2016 THL1_RS02255 e561adf6ca15ed70308a233a5fe58d90 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 4.9E-18 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS02255 e561adf6ca15ed70308a233a5fe58d90 302 SUPERFAMILY SSF46785 4 112 4.61E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20415 136988a7ecaf7771a64889587e4e56ae 378 Pfam PF00296 Luciferase-like monooxygenase 15 339 9.2E-35 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS20415 136988a7ecaf7771a64889587e4e56ae 378 PANTHER PTHR30011:SF6 1 373 4.3E-49 T 13-09-2016 THL1_RS20415 136988a7ecaf7771a64889587e4e56ae 378 SUPERFAMILY SSF51679 3 373 9.94E-61 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS20415 136988a7ecaf7771a64889587e4e56ae 378 Gene3D G3DSA:3.20.20.30 3 373 3.1E-66 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS20415 136988a7ecaf7771a64889587e4e56ae 378 PANTHER PTHR30011 1 373 4.3E-49 T 13-09-2016 THL1_RS22235 4e94778ddd320e585e60eed64a2873be 135 Pfam PF09842 Predicted membrane protein (DUF2069) 24 125 7.1E-30 T 13-09-2016 IPR018643 Protein of unknown function DUF2069, membrane THL1_RS13935 2d21f9f963c13f5fe72109287563704e 452 Gene3D G3DSA:2.50.20.10 340 412 2.6E-33 T 13-09-2016 THL1_RS13935 2d21f9f963c13f5fe72109287563704e 452 Gene3D G3DSA:2.50.20.10 159 308 2.6E-33 T 13-09-2016 THL1_RS13935 2d21f9f963c13f5fe72109287563704e 452 Pfam PF07044 Protein of unknown function (DUF1329) 84 429 7.6E-132 T 13-09-2016 IPR010752 Protein of unknown function DUF1329 THL1_RS05555 69d99fb0741d5d1632fd6d4916d48d2c 205 PANTHER PTHR11260:SF44 1 205 2.4E-109 T 13-09-2016 THL1_RS05555 69d99fb0741d5d1632fd6d4916d48d2c 205 Pfam PF00043 Glutathione S-transferase, C-terminal domain 108 191 3.9E-8 T 13-09-2016 IPR004046 Glutathione S-transferase, C-terminal THL1_RS05555 69d99fb0741d5d1632fd6d4916d48d2c 205 SUPERFAMILY SSF52833 10 104 5.71E-23 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS05555 69d99fb0741d5d1632fd6d4916d48d2c 205 PANTHER PTHR11260 1 205 2.4E-109 T 13-09-2016 THL1_RS05555 69d99fb0741d5d1632fd6d4916d48d2c 205 Gene3D G3DSA:1.20.1050.10 102 200 4.1E-17 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS05555 69d99fb0741d5d1632fd6d4916d48d2c 205 Pfam PF13417 Glutathione S-transferase, N-terminal domain 10 83 1.8E-19 T 13-09-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THL1_RS05555 69d99fb0741d5d1632fd6d4916d48d2c 205 Gene3D G3DSA:3.40.30.10 5 101 2.6E-29 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS05555 69d99fb0741d5d1632fd6d4916d48d2c 205 SUPERFAMILY SSF47616 78 205 2.09E-29 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS04265 baae2b6a556af3932a04030147c87ddc 350 Gene3D G3DSA:3.20.20.70 61 321 5.5E-65 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS04265 baae2b6a556af3932a04030147c87ddc 350 SUPERFAMILY SSF102114 56 318 9.81E-59 T 13-09-2016 THL1_RS04265 baae2b6a556af3932a04030147c87ddc 350 Pfam PF04055 Radical SAM superfamily 97 258 2.7E-14 T 13-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 THL1_RS04265 baae2b6a556af3932a04030147c87ddc 350 Hamap MF_00206 Lipoyl synthase [lipA]. 43 329 135.868 T 13-09-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 THL1_RS04265 baae2b6a556af3932a04030147c87ddc 350 SMART SM00729 89 299 3.0E-12 T 13-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THL1_RS04265 baae2b6a556af3932a04030147c87ddc 350 PANTHER PTHR10949 41 326 1.1E-171 T 13-09-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 THL1_RS04265 baae2b6a556af3932a04030147c87ddc 350 TIGRFAM TIGR00510 lipA: lipoyl synthase 37 325 3.9E-119 T 13-09-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 THL1_RS04265 baae2b6a556af3932a04030147c87ddc 350 PIRSF PIRSF005963 2 332 4.5E-141 T 13-09-2016 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|UniPathway: UPA00538 THL1_RS23155 5570c3d6c4b2a8d2f193523e9de8c10f 267 Pfam PF13174 Tetratricopeptide repeat 92 127 2.4E-4 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS23155 5570c3d6c4b2a8d2f193523e9de8c10f 267 Pfam PF13174 Tetratricopeptide repeat 213 248 0.0012 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS23155 5570c3d6c4b2a8d2f193523e9de8c10f 267 Gene3D G3DSA:1.25.40.10 176 242 5.4E-6 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS23155 5570c3d6c4b2a8d2f193523e9de8c10f 267 Gene3D G3DSA:1.25.40.10 90 130 5.4E-6 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS23155 5570c3d6c4b2a8d2f193523e9de8c10f 267 SUPERFAMILY SSF81901 168 244 3.27E-5 T 13-09-2016 THL1_RS23155 5570c3d6c4b2a8d2f193523e9de8c10f 267 SUPERFAMILY SSF81901 86 120 3.27E-5 T 13-09-2016 THL1_RS08365 9ef02fc9de653082a18aac40ade1c9bf 118 PANTHER PTHR30561:SF2 1 111 3.3E-59 T 13-09-2016 IPR023740 Spermidine export protein MdtJ GO:0005886|GO:0015606|GO:0015848 THL1_RS08365 9ef02fc9de653082a18aac40ade1c9bf 118 Pfam PF00893 Small Multidrug Resistance protein 3 93 8.3E-24 T 13-09-2016 IPR000390 Small multidrug resistance protein family GO:0016021 THL1_RS08365 9ef02fc9de653082a18aac40ade1c9bf 118 SUPERFAMILY SSF103481 5 105 1.27E-16 T 13-09-2016 THL1_RS08365 9ef02fc9de653082a18aac40ade1c9bf 118 PANTHER PTHR30561 1 111 3.3E-59 T 13-09-2016 THL1_RS11205 6d5a6b3218787ee9976a824f3ed32a47 317 PIRSF PIRSF036979 15 314 9.0E-94 T 13-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 THL1_RS11205 6d5a6b3218787ee9976a824f3ed32a47 317 Pfam PF00491 Arginase family 37 307 7.3E-89 T 13-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 THL1_RS11205 6d5a6b3218787ee9976a824f3ed32a47 317 PRINTS PR00116 Arginase signature 122 137 9.4E-12 T 13-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 THL1_RS11205 6d5a6b3218787ee9976a824f3ed32a47 317 PRINTS PR00116 Arginase signature 235 264 9.4E-12 T 13-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 THL1_RS11205 6d5a6b3218787ee9976a824f3ed32a47 317 PANTHER PTHR11358:SF27 1 310 1.6E-112 T 13-09-2016 THL1_RS11205 6d5a6b3218787ee9976a824f3ed32a47 317 SUPERFAMILY SSF52768 4 312 3.96E-97 T 13-09-2016 THL1_RS11205 6d5a6b3218787ee9976a824f3ed32a47 317 Gene3D G3DSA:3.40.800.10 11 312 2.3E-110 T 13-09-2016 IPR023696 Ureohydrolase domain THL1_RS11205 6d5a6b3218787ee9976a824f3ed32a47 317 PANTHER PTHR11358 1 310 1.6E-112 T 13-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 THL1_RS11205 6d5a6b3218787ee9976a824f3ed32a47 317 TIGRFAM TIGR01230 agmatinase: agmatinase 36 308 4.8E-57 T 13-09-2016 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|UniPathway: UPA00534 THL1_RS11205 6d5a6b3218787ee9976a824f3ed32a47 317 ProSitePatterns PS01053 Arginase family signature. 238 259 - T 13-09-2016 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 Reactome: REACT_13 THL1_RS06580 88c959125a0a35f5f1b0d1573e590260 170 SUPERFAMILY SSF143744 31 165 2.75E-37 T 13-09-2016 THL1_RS06580 88c959125a0a35f5f1b0d1573e590260 170 PANTHER PTHR34309 2 169 2.6E-36 T 13-09-2016 THL1_RS06580 88c959125a0a35f5f1b0d1573e590260 170 PANTHER PTHR34309:SF1 2 169 2.6E-36 T 13-09-2016 THL1_RS06580 88c959125a0a35f5f1b0d1573e590260 170 Pfam PF03928 Haem-degrading 37 163 1.1E-30 T 13-09-2016 IPR005624 Haem-degrading THL1_RS10525 b2ba6ffdfe3b361f7f64dcd69b87d08c 179 PIRSF PIRSF006443 1 167 2.4E-65 T 13-09-2016 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 UniPathway: UPA00344 THL1_RS10525 b2ba6ffdfe3b361f7f64dcd69b87d08c 179 PANTHER PTHR10192:SF18 5 174 1.9E-94 T 13-09-2016 THL1_RS10525 b2ba6ffdfe3b361f7f64dcd69b87d08c 179 SUPERFAMILY SSF53218 7 169 4.58E-47 T 13-09-2016 IPR001453 MoaB/Mog domain THL1_RS10525 b2ba6ffdfe3b361f7f64dcd69b87d08c 179 SMART SM00852 15 159 6.9E-31 T 13-09-2016 IPR001453 MoaB/Mog domain THL1_RS10525 b2ba6ffdfe3b361f7f64dcd69b87d08c 179 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 13 152 5.5E-33 T 13-09-2016 IPR001453 MoaB/Mog domain THL1_RS10525 b2ba6ffdfe3b361f7f64dcd69b87d08c 179 Pfam PF00994 Probable molybdopterin binding domain 15 157 7.2E-33 T 13-09-2016 IPR001453 MoaB/Mog domain THL1_RS10525 b2ba6ffdfe3b361f7f64dcd69b87d08c 179 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 9 169 1.1E-84 T 13-09-2016 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 UniPathway: UPA00344 THL1_RS10525 b2ba6ffdfe3b361f7f64dcd69b87d08c 179 PANTHER PTHR10192 5 174 1.9E-94 T 13-09-2016 THL1_RS10525 b2ba6ffdfe3b361f7f64dcd69b87d08c 179 Gene3D G3DSA:3.40.980.10 5 169 2.2E-47 T 13-09-2016 IPR001453 MoaB/Mog domain THL1_RS10525 b2ba6ffdfe3b361f7f64dcd69b87d08c 179 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 73 86 - T 13-09-2016 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 UniPathway: UPA00344 THL1_RS26715 38a45746900a1e6cfed578dad8b72b92 421 Gene3D G3DSA:2.70.70.10 289 418 1.7E-37 T 13-09-2016 THL1_RS26715 38a45746900a1e6cfed578dad8b72b92 421 Pfam PF01551 Peptidase family M23 320 413 3.7E-25 T 13-09-2016 IPR016047 Peptidase M23 THL1_RS26715 38a45746900a1e6cfed578dad8b72b92 421 PANTHER PTHR21666 32 416 4.3E-44 T 13-09-2016 THL1_RS26715 38a45746900a1e6cfed578dad8b72b92 421 SUPERFAMILY SSF51261 232 417 7.32E-46 T 13-09-2016 IPR011055 Duplicated hybrid motif THL1_RS26715 38a45746900a1e6cfed578dad8b72b92 421 PANTHER PTHR21666:SF108 32 416 4.3E-44 T 13-09-2016 THL1_RS20920 72ddb410c852dcc37409d16ef9c32a91 261 SUPERFAMILY SSF52096 9 253 3.52E-68 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20920 72ddb410c852dcc37409d16ef9c32a91 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 253 3.4E-48 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS20920 72ddb410c852dcc37409d16ef9c32a91 261 Gene3D G3DSA:3.90.226.10 9 253 5.6E-66 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20920 72ddb410c852dcc37409d16ef9c32a91 261 PANTHER PTHR11941 3 252 2.6E-68 T 13-09-2016 THL1_RS20455 43466ebc065b54af34a7bb939a99ef85 367 PANTHER PTHR11941:SF53 1 189 1.7E-106 T 13-09-2016 THL1_RS20455 43466ebc065b54af34a7bb939a99ef85 367 Pfam PF16113 Enoyl-CoA hydratase/isomerase 16 348 8.2E-121 T 13-09-2016 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 THL1_RS20455 43466ebc065b54af34a7bb939a99ef85 367 SUPERFAMILY SSF52096 7 189 3.38E-70 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20455 43466ebc065b54af34a7bb939a99ef85 367 SUPERFAMILY SSF52096 258 355 3.38E-70 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20455 43466ebc065b54af34a7bb939a99ef85 367 PANTHER PTHR11941 254 331 1.7E-106 T 13-09-2016 THL1_RS20455 43466ebc065b54af34a7bb939a99ef85 367 PANTHER PTHR11941 1 189 1.7E-106 T 13-09-2016 THL1_RS20455 43466ebc065b54af34a7bb939a99ef85 367 PANTHER PTHR11941:SF53 254 331 1.7E-106 T 13-09-2016 THL1_RS20455 43466ebc065b54af34a7bb939a99ef85 367 Gene3D G3DSA:3.90.226.10 6 194 1.2E-55 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20455 43466ebc065b54af34a7bb939a99ef85 367 Gene3D G3DSA:1.10.12.10 273 320 2.5E-5 T 13-09-2016 IPR014748 Crontonase, C-terminal THL1_RS00630 e541f599c870add55b6521678a422af3 406 SMART SM00448 8 123 7.8E-18 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS00630 e541f599c870add55b6521678a422af3 406 PANTHER PTHR26402 8 127 8.8E-24 T 13-09-2016 THL1_RS00630 e541f599c870add55b6521678a422af3 406 Pfam PF00072 Response regulator receiver domain 10 123 9.4E-16 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS00630 e541f599c870add55b6521678a422af3 406 Gene3D G3DSA:1.10.3150.10 162 397 2.4E-32 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS00630 e541f599c870add55b6521678a422af3 406 Gene3D G3DSA:3.40.50.2300 5 127 5.9E-24 T 13-09-2016 THL1_RS00630 e541f599c870add55b6521678a422af3 406 SUPERFAMILY SSF52172 8 127 9.68E-25 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS00630 e541f599c870add55b6521678a422af3 406 Pfam PF08668 HDOD domain 162 349 5.8E-35 T 13-09-2016 IPR013976 Metal-dependent hydrolase HDOD THL1_RS00630 e541f599c870add55b6521678a422af3 406 SUPERFAMILY SSF109604 151 397 4.19E-36 T 13-09-2016 THL1_RS09060 3e5e16dc47dd3883fd4ff47fbb7f6779 188 SUPERFAMILY SSF53254 1 184 7.71E-49 T 13-09-2016 IPR029033 Histidine phosphatase superfamily THL1_RS09060 3e5e16dc47dd3883fd4ff47fbb7f6779 188 Gene3D G3DSA:3.40.50.1240 1 184 1.1E-47 T 13-09-2016 IPR029033 Histidine phosphatase superfamily THL1_RS09060 3e5e16dc47dd3883fd4ff47fbb7f6779 188 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 184 5.0E-46 T 13-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 THL1_RS09060 3e5e16dc47dd3883fd4ff47fbb7f6779 188 PANTHER PTHR23029 1 155 6.9E-40 T 13-09-2016 THL1_RS09060 3e5e16dc47dd3883fd4ff47fbb7f6779 188 PANTHER PTHR23029:SF1 1 155 6.9E-40 T 13-09-2016 THL1_RS09060 3e5e16dc47dd3883fd4ff47fbb7f6779 188 SMART SM00855 2 152 1.3E-15 T 13-09-2016 IPR013078 Histidine phosphatase superfamily, clade-1 THL1_RS28055 59cba5ddee74dd968e65393547ca0245 135 Gene3D G3DSA:3.10.129.10 10 132 4.3E-32 T 13-09-2016 IPR029069 HotDog domain THL1_RS28055 59cba5ddee74dd968e65393547ca0245 135 Pfam PF03061 Thioesterase superfamily 30 104 4.8E-16 T 13-09-2016 IPR006683 Thioesterase domain THL1_RS28055 59cba5ddee74dd968e65393547ca0245 135 PANTHER PTHR11049 6 135 1.3E-60 T 13-09-2016 THL1_RS28055 59cba5ddee74dd968e65393547ca0245 135 PANTHER PTHR11049:SF5 6 135 1.3E-60 T 13-09-2016 THL1_RS28055 59cba5ddee74dd968e65393547ca0245 135 SUPERFAMILY SSF54637 12 132 4.05E-31 T 13-09-2016 IPR029069 HotDog domain THL1_RS26385 902e69db84ec434806c72d9fb6c6b34a 559 PANTHER PTHR36837 1 559 1.1E-278 T 13-09-2016 THL1_RS26385 902e69db84ec434806c72d9fb6c6b34a 559 SUPERFAMILY SSF53474 188 490 3.12E-36 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS26385 902e69db84ec434806c72d9fb6c6b34a 559 Gene3D G3DSA:3.40.50.1820 160 529 1.2E-59 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS26385 902e69db84ec434806c72d9fb6c6b34a 559 TIGRFAM TIGR01839 PHA_synth_II: poly(R)-hydroxyalkanoic acid synthase, class II 1 559 0.0 T 13-09-2016 IPR011287 Poly(R)-hydroxyalkanoic acid synthase, class II GO:0016746|GO:0042619 KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.- THL1_RS26385 902e69db84ec434806c72d9fb6c6b34a 559 PANTHER PTHR36837:SF2 1 559 1.1E-278 T 13-09-2016 THL1_RS26385 902e69db84ec434806c72d9fb6c6b34a 559 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 75 243 8.1E-66 T 13-09-2016 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.- THL1_RS06400 89ea4249bd675ddf1a5e064a08dcf4bf 341 Gene3D G3DSA:1.10.8.300 229 336 2.4E-32 T 13-09-2016 THL1_RS06400 89ea4249bd675ddf1a5e064a08dcf4bf 341 PANTHER PTHR11603 27 340 3.4E-184 T 13-09-2016 THL1_RS06400 89ea4249bd675ddf1a5e064a08dcf4bf 341 SUPERFAMILY SSF52540 31 313 2.35E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06400 89ea4249bd675ddf1a5e064a08dcf4bf 341 Gene3D G3DSA:3.40.50.300 44 207 6.6E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06400 89ea4249bd675ddf1a5e064a08dcf4bf 341 PANTHER PTHR11603:SF149 27 340 3.4E-184 T 13-09-2016 THL1_RS06400 89ea4249bd675ddf1a5e064a08dcf4bf 341 SMART SM00382 59 202 1.2E-5 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS06400 89ea4249bd675ddf1a5e064a08dcf4bf 341 PIRSF PIRSF002849 1 341 1.3E-130 T 13-09-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted THL1_RS06400 89ea4249bd675ddf1a5e064a08dcf4bf 341 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 62 192 6.7E-65 T 13-09-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 THL1_RS08980 e3c45973221941ae923ce78072c1ec75 254 PANTHER PTHR11085:SF17 2 254 4.4E-73 T 13-09-2016 THL1_RS08980 e3c45973221941ae923ce78072c1ec75 254 Pfam PF02146 Sir2 family 22 199 8.8E-37 T 13-09-2016 IPR003000 Sirtuin family GO:0070403 THL1_RS08980 e3c45973221941ae923ce78072c1ec75 254 PANTHER PTHR11085 2 254 4.4E-73 T 13-09-2016 IPR003000 Sirtuin family GO:0070403 THL1_RS08980 e3c45973221941ae923ce78072c1ec75 254 SUPERFAMILY SSF52467 2 251 1.73E-69 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS08980 e3c45973221941ae923ce78072c1ec75 254 Gene3D G3DSA:3.30.1600.10 127 172 3.0E-18 T 13-09-2016 IPR026591 Sirtuin family, catalytic core small domain THL1_RS08980 e3c45973221941ae923ce78072c1ec75 254 Gene3D G3DSA:3.30.1600.10 33 75 3.0E-18 T 13-09-2016 IPR026591 Sirtuin family, catalytic core small domain THL1_RS08980 e3c45973221941ae923ce78072c1ec75 254 Gene3D G3DSA:3.40.50.1220 179 251 1.4E-32 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS08980 e3c45973221941ae923ce78072c1ec75 254 Gene3D G3DSA:3.40.50.1220 2 32 1.4E-32 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS08980 e3c45973221941ae923ce78072c1ec75 254 Gene3D G3DSA:3.40.50.1220 87 126 1.4E-32 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS25785 9f7f6924a5e9d703a1144ebb4a79188d 148 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 9.0E-21 T 13-09-2016 IPR020070 Ribosomal protein L9, N-terminal THL1_RS25785 9f7f6924a5e9d703a1144ebb4a79188d 148 Gene3D G3DSA:3.10.430.100 61 147 9.0E-28 T 13-09-2016 IPR020069 Ribosomal protein L9, C-terminal THL1_RS25785 9f7f6924a5e9d703a1144ebb4a79188d 148 Gene3D G3DSA:3.40.5.10 1 52 3.3E-24 T 13-09-2016 IPR020070 Ribosomal protein L9, N-terminal THL1_RS25785 9f7f6924a5e9d703a1144ebb4a79188d 148 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 147 2.0E-25 T 13-09-2016 IPR020069 Ribosomal protein L9, C-terminal THL1_RS25785 9f7f6924a5e9d703a1144ebb4a79188d 148 PANTHER PTHR21368 1 147 2.4E-50 T 13-09-2016 IPR000244 Ribosomal protein L9 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS25785 9f7f6924a5e9d703a1144ebb4a79188d 148 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 1.7E-50 T 13-09-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS25785 9f7f6924a5e9d703a1144ebb4a79188d 148 SUPERFAMILY SSF55653 60 147 7.72E-25 T 13-09-2016 IPR020069 Ribosomal protein L9, C-terminal THL1_RS25785 9f7f6924a5e9d703a1144ebb4a79188d 148 SUPERFAMILY SSF55658 1 57 5.93E-18 T 13-09-2016 IPR009027 Ribosomal protein L9/RNase H1, N-terminal THL1_RS25785 9f7f6924a5e9d703a1144ebb4a79188d 148 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 13-09-2016 IPR020070 Ribosomal protein L9, N-terminal THL1_RS25785 9f7f6924a5e9d703a1144ebb4a79188d 148 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.306 T 13-09-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS09225 8bac7970cfc98707137feafa74c43337 580 Gene3D G3DSA:3.20.20.140 522 575 5.0E-10 T 13-09-2016 THL1_RS09225 8bac7970cfc98707137feafa74c43337 580 SUPERFAMILY SSF51556 82 103 2.88E-34 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS09225 8bac7970cfc98707137feafa74c43337 580 SUPERFAMILY SSF51556 226 536 2.88E-34 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS09225 8bac7970cfc98707137feafa74c43337 580 PANTHER PTHR22642:SF9 1 578 9.9E-239 T 13-09-2016 THL1_RS09225 8bac7970cfc98707137feafa74c43337 580 Gene3D G3DSA:2.30.40.10 15 92 1.7E-21 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS09225 8bac7970cfc98707137feafa74c43337 580 Gene3D G3DSA:3.20.20.140 93 105 7.0E-26 T 13-09-2016 THL1_RS09225 8bac7970cfc98707137feafa74c43337 580 Gene3D G3DSA:3.20.20.140 228 521 7.0E-26 T 13-09-2016 THL1_RS09225 8bac7970cfc98707137feafa74c43337 580 SUPERFAMILY SSF51338 535 578 1.64E-24 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS09225 8bac7970cfc98707137feafa74c43337 580 SUPERFAMILY SSF51338 17 83 1.64E-24 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS09225 8bac7970cfc98707137feafa74c43337 580 Pfam PF07969 Amidohydrolase family 71 576 4.1E-76 T 13-09-2016 IPR013108 Amidohydrolase 3 THL1_RS09225 8bac7970cfc98707137feafa74c43337 580 PANTHER PTHR22642 1 578 9.9E-239 T 13-09-2016 THL1_RS03190 da95c2bb177be9c08218d6f68e339cee 122 Gene3D G3DSA:1.10.760.10 21 121 2.5E-32 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS03190 da95c2bb177be9c08218d6f68e339cee 122 PANTHER PTHR11961 6 120 9.4E-24 T 13-09-2016 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 THL1_RS03190 da95c2bb177be9c08218d6f68e339cee 122 PRINTS PR00604 Class IA and IB cytochrome C signature 76 92 1.0E-16 T 13-09-2016 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 THL1_RS03190 da95c2bb177be9c08218d6f68e339cee 122 PRINTS PR00604 Class IA and IB cytochrome C signature 46 61 1.0E-16 T 13-09-2016 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 THL1_RS03190 da95c2bb177be9c08218d6f68e339cee 122 PRINTS PR00604 Class IA and IB cytochrome C signature 95 105 1.0E-16 T 13-09-2016 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 THL1_RS03190 da95c2bb177be9c08218d6f68e339cee 122 PRINTS PR00604 Class IA and IB cytochrome C signature 62 72 1.0E-16 T 13-09-2016 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 THL1_RS03190 da95c2bb177be9c08218d6f68e339cee 122 PRINTS PR00604 Class IA and IB cytochrome C signature 34 41 1.0E-16 T 13-09-2016 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 THL1_RS03190 da95c2bb177be9c08218d6f68e339cee 122 PRINTS PR00604 Class IA and IB cytochrome C signature 112 120 1.0E-16 T 13-09-2016 IPR002327 Cytochrome c, class IA/ IB GO:0009055|GO:0020037 THL1_RS03190 da95c2bb177be9c08218d6f68e339cee 122 Pfam PF00034 Cytochrome c 24 122 4.6E-11 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS03190 da95c2bb177be9c08218d6f68e339cee 122 SUPERFAMILY SSF46626 21 122 2.03E-29 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS19245 d7eacb298d08204251893ad15a96b941 275 Hamap MF_01805 Segregation and condensation protein A [scpA]. 44 274 21.617 T 13-09-2016 IPR003768 Segregation and condensation protein A THL1_RS19245 d7eacb298d08204251893ad15a96b941 275 PANTHER PTHR33969 28 275 5.8E-92 T 13-09-2016 THL1_RS19245 d7eacb298d08204251893ad15a96b941 275 Pfam PF02616 Segregation and condensation protein ScpA 61 270 1.1E-27 T 13-09-2016 IPR003768 Segregation and condensation protein A THL1_RS19245 d7eacb298d08204251893ad15a96b941 275 PANTHER PTHR33969:SF2 28 275 5.8E-92 T 13-09-2016 THL1_RS15585 d912f0cfb08824b6894397b62b652cd1 307 Gene3D G3DSA:1.10.10.10 1 85 1.5E-29 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS15585 d912f0cfb08824b6894397b62b652cd1 307 SUPERFAMILY SSF53850 90 294 5.25E-47 T 13-09-2016 THL1_RS15585 d912f0cfb08824b6894397b62b652cd1 307 Gene3D G3DSA:3.40.190.10 270 300 2.6E-32 T 13-09-2016 THL1_RS15585 d912f0cfb08824b6894397b62b652cd1 307 Gene3D G3DSA:3.40.190.10 90 172 2.6E-32 T 13-09-2016 THL1_RS15585 d912f0cfb08824b6894397b62b652cd1 307 Pfam PF03466 LysR substrate binding domain 96 295 4.5E-28 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS15585 d912f0cfb08824b6894397b62b652cd1 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.9E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS15585 d912f0cfb08824b6894397b62b652cd1 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.9E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS15585 d912f0cfb08824b6894397b62b652cd1 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.9E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS15585 d912f0cfb08824b6894397b62b652cd1 307 SUPERFAMILY SSF46785 2 82 3.86E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS15585 d912f0cfb08824b6894397b62b652cd1 307 PANTHER PTHR30118:SF4 1 304 4.4E-143 T 13-09-2016 THL1_RS15585 d912f0cfb08824b6894397b62b652cd1 307 PANTHER PTHR30118 1 304 4.4E-143 T 13-09-2016 THL1_RS15585 d912f0cfb08824b6894397b62b652cd1 307 Gene3D G3DSA:3.40.190.10 173 262 1.6E-26 T 13-09-2016 THL1_RS15585 d912f0cfb08824b6894397b62b652cd1 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 4.1E-16 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS05430 0a77a58e0e5b409f16861a40c2f83c5b 211 PANTHER PTHR21403:SF3 1 209 1.5E-95 T 13-09-2016 THL1_RS05430 0a77a58e0e5b409f16861a40c2f83c5b 211 Pfam PF01634 ATP phosphoribosyltransferase 51 202 1.3E-45 T 13-09-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 THL1_RS05430 0a77a58e0e5b409f16861a40c2f83c5b 211 Gene3D G3DSA:3.40.190.10 1 113 3.2E-33 T 13-09-2016 THL1_RS05430 0a77a58e0e5b409f16861a40c2f83c5b 211 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 13-09-2016 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 THL1_RS05430 0a77a58e0e5b409f16861a40c2f83c5b 211 SUPERFAMILY SSF53850 1 205 3.26E-64 T 13-09-2016 THL1_RS05430 0a77a58e0e5b409f16861a40c2f83c5b 211 PANTHER PTHR21403 1 209 1.5E-95 T 13-09-2016 IPR001348 ATP phosphoribosyltransferase HisG GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 THL1_RS05430 0a77a58e0e5b409f16861a40c2f83c5b 211 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 1.5E-53 T 13-09-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 THL1_RS05430 0a77a58e0e5b409f16861a40c2f83c5b 211 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 1 206 56.782 T 13-09-2016 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 THL1_RS05430 0a77a58e0e5b409f16861a40c2f83c5b 211 Gene3D G3DSA:3.40.190.10 114 173 6.3E-28 T 13-09-2016 THL1_RS22585 b6065661727c37056b2a57162712b47a 146 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 142 1.1E-63 T 13-09-2016 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 THL1_RS22585 b6065661727c37056b2a57162712b47a 146 Gene3D G3DSA:3.10.129.10 1 142 1.1E-59 T 13-09-2016 IPR029069 HotDog domain THL1_RS22585 b6065661727c37056b2a57162712b47a 146 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 145 36.147 T 13-09-2016 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 THL1_RS22585 b6065661727c37056b2a57162712b47a 146 Pfam PF07977 FabA-like domain 11 137 3.6E-40 T 13-09-2016 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 THL1_RS22585 b6065661727c37056b2a57162712b47a 146 PANTHER PTHR30272 1 146 2.4E-81 T 13-09-2016 THL1_RS22585 b6065661727c37056b2a57162712b47a 146 SUPERFAMILY SSF54637 1 142 4.49E-53 T 13-09-2016 IPR029069 HotDog domain THL1_RS05345 c37abb50093f4dfd9cee0c5937bf5b76 90 PANTHER PTHR33705:SF2 1 90 4.4E-39 T 13-09-2016 THL1_RS05345 c37abb50093f4dfd9cee0c5937bf5b76 90 Gene3D G3DSA:3.30.1340.10 1 88 9.0E-27 T 13-09-2016 IPR000032 Phosphocarrier HPr protein-like THL1_RS05345 c37abb50093f4dfd9cee0c5937bf5b76 90 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 13-09-2016 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site THL1_RS05345 c37abb50093f4dfd9cee0c5937bf5b76 90 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 83 3.4E-24 T 13-09-2016 IPR000032 Phosphocarrier HPr protein-like THL1_RS05345 c37abb50093f4dfd9cee0c5937bf5b76 90 PRINTS PR00107 Phosphocarrier protein signature 39 54 5.3E-9 T 13-09-2016 IPR000032 Phosphocarrier HPr protein-like THL1_RS05345 c37abb50093f4dfd9cee0c5937bf5b76 90 PRINTS PR00107 Phosphocarrier protein signature 13 29 5.3E-9 T 13-09-2016 IPR000032 Phosphocarrier HPr protein-like THL1_RS05345 c37abb50093f4dfd9cee0c5937bf5b76 90 PRINTS PR00107 Phosphocarrier protein signature 54 71 5.3E-9 T 13-09-2016 IPR000032 Phosphocarrier HPr protein-like THL1_RS05345 c37abb50093f4dfd9cee0c5937bf5b76 90 SUPERFAMILY SSF55594 1 88 2.09E-25 T 13-09-2016 IPR000032 Phosphocarrier HPr protein-like THL1_RS05345 c37abb50093f4dfd9cee0c5937bf5b76 90 PANTHER PTHR33705 1 90 4.4E-39 T 13-09-2016 THL1_RS05345 c37abb50093f4dfd9cee0c5937bf5b76 90 Pfam PF00381 PTS HPr component phosphorylation site 5 83 8.0E-25 T 13-09-2016 IPR000032 Phosphocarrier HPr protein-like THL1_RS26445 68d2e5fb6937a136f8114058cf75ce60 85 Pfam PF02416 mttA/Hcf106 family 6 50 1.6E-12 T 13-09-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 THL1_RS26445 68d2e5fb6937a136f8114058cf75ce60 85 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 83 21.64 T 13-09-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 THL1_RS26445 68d2e5fb6937a136f8114058cf75ce60 85 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 47 2.1E-21 T 13-09-2016 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 THL1_RS26445 68d2e5fb6937a136f8114058cf75ce60 85 PANTHER PTHR33162 1 53 2.3E-15 T 13-09-2016 THL1_RS19815 4456dcf9141e1c8f327f54a049d65ccd 364 PIRSF PIRSF019574 2 364 3.4E-120 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19815 4456dcf9141e1c8f327f54a049d65ccd 364 SUPERFAMILY SSF53850 26 363 2.22E-94 T 13-09-2016 THL1_RS19815 4456dcf9141e1c8f327f54a049d65ccd 364 Gene3D G3DSA:3.40.190.10 27 138 8.0E-21 T 13-09-2016 THL1_RS19815 4456dcf9141e1c8f327f54a049d65ccd 364 PANTHER PTHR30222 5 364 3.6E-134 T 13-09-2016 THL1_RS19815 4456dcf9141e1c8f327f54a049d65ccd 364 Pfam PF13416 Bacterial extracellular solute-binding protein 43 329 6.3E-28 T 13-09-2016 THL1_RS19815 4456dcf9141e1c8f327f54a049d65ccd 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 47 68 8.8E-54 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19815 4456dcf9141e1c8f327f54a049d65ccd 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 263 282 8.8E-54 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19815 4456dcf9141e1c8f327f54a049d65ccd 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 308 334 8.8E-54 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19815 4456dcf9141e1c8f327f54a049d65ccd 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 31 47 8.8E-54 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19815 4456dcf9141e1c8f327f54a049d65ccd 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 90 103 8.8E-54 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19815 4456dcf9141e1c8f327f54a049d65ccd 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 123 139 8.8E-54 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19815 4456dcf9141e1c8f327f54a049d65ccd 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 74 88 8.8E-54 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19815 4456dcf9141e1c8f327f54a049d65ccd 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 176 195 8.8E-54 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19815 4456dcf9141e1c8f327f54a049d65ccd 364 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 213 232 8.8E-54 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS19815 4456dcf9141e1c8f327f54a049d65ccd 364 Gene3D G3DSA:3.40.190.10 139 312 2.7E-64 T 13-09-2016 THL1_RS19815 4456dcf9141e1c8f327f54a049d65ccd 364 PANTHER PTHR30222:SF11 5 364 3.6E-134 T 13-09-2016 THL1_RS02930 66b7b94530e713ae362555be85d7a815 249 SMART SM00382 99 232 2.5E-6 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS02930 66b7b94530e713ae362555be85d7a815 249 PANTHER PTHR30050:SF6 10 241 1.4E-67 T 13-09-2016 THL1_RS02930 66b7b94530e713ae362555be85d7a815 249 PIRSF PIRSF003073 1 249 1.0E-69 T 13-09-2016 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein THL1_RS02930 66b7b94530e713ae362555be85d7a815 249 SUPERFAMILY SSF52540 68 238 5.91E-24 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS02930 66b7b94530e713ae362555be85d7a815 249 Pfam PF08483 IstB-like ATP binding N-terminal 24 52 2.7E-13 T 13-09-2016 IPR013690 IstB-like ATP binding N-terminal THL1_RS02930 66b7b94530e713ae362555be85d7a815 249 Gene3D G3DSA:3.40.50.300 56 230 4.9E-28 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS02930 66b7b94530e713ae362555be85d7a815 249 Pfam PF01695 IstB-like ATP binding protein 54 230 1.1E-63 T 13-09-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 THL1_RS02930 66b7b94530e713ae362555be85d7a815 249 PANTHER PTHR30050 10 241 1.4E-67 T 13-09-2016 THL1_RS03575 12a75f48fb98752adcc817ab9c111475 122 Gene3D G3DSA:2.40.150.20 1 122 6.3E-56 T 13-09-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 THL1_RS03575 12a75f48fb98752adcc817ab9c111475 122 SMART SM01374 1 122 7.4E-87 T 13-09-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 THL1_RS03575 12a75f48fb98752adcc817ab9c111475 122 PANTHER PTHR11761 1 122 1.1E-78 T 13-09-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 THL1_RS03575 12a75f48fb98752adcc817ab9c111475 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.201 T 13-09-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 THL1_RS03575 12a75f48fb98752adcc817ab9c111475 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 2.3E-55 T 13-09-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 THL1_RS03575 12a75f48fb98752adcc817ab9c111475 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.3E-58 T 13-09-2016 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 THL1_RS03575 12a75f48fb98752adcc817ab9c111475 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 13-09-2016 IPR019972 Ribosomal protein L14P, conserved site THL1_RS03575 12a75f48fb98752adcc817ab9c111475 122 SUPERFAMILY SSF50193 1 122 1.96E-52 T 13-09-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 THL1_RS21275 22c5e1500fa5b02c798f347a81626640 322 Pfam PF08003 Protein of unknown function (DUF1698) 11 321 1.4E-140 T 13-09-2016 IPR027555 tRNA (mo5U34)-methyltransferase-like THL1_RS21275 22c5e1500fa5b02c798f347a81626640 322 SUPERFAMILY SSF53335 91 322 1.09E-29 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS21275 22c5e1500fa5b02c798f347a81626640 322 PANTHER PTHR10108:SF847 83 321 3.0E-100 T 13-09-2016 THL1_RS21275 22c5e1500fa5b02c798f347a81626640 322 TIGRFAM TIGR00452 TIGR00452: tRNA (mo5U34)-methyltransferase 12 320 1.5E-139 T 13-09-2016 IPR010017 tRNA (mo5U34)-methyltransferase GO:0002098|GO:0016300 THL1_RS21275 22c5e1500fa5b02c798f347a81626640 322 Gene3D G3DSA:3.40.50.150 120 321 4.8E-20 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS21275 22c5e1500fa5b02c798f347a81626640 322 PANTHER PTHR10108 83 321 3.0E-100 T 13-09-2016 THL1_RS21275 22c5e1500fa5b02c798f347a81626640 322 Hamap MF_01590 tRNA (mo5U34)-methyltransferase [cmoB]. 15 321 53.073 T 13-09-2016 IPR010017 tRNA (mo5U34)-methyltransferase GO:0002098|GO:0016300 THL1_RS06540 42cb3603c82d936363ca518bf426cceb 95 Gene3D G3DSA:3.10.129.10 1 59 8.0E-8 T 13-09-2016 IPR029069 HotDog domain THL1_RS06540 42cb3603c82d936363ca518bf426cceb 95 SUPERFAMILY SSF54637 2 56 7.88E-10 T 13-09-2016 IPR029069 HotDog domain THL1_RS13360 8be3730820b7a0d292f152a4949bf13d 253 PANTHER PTHR14194:SF69 1 244 6.9E-100 T 13-09-2016 THL1_RS13360 8be3730820b7a0d292f152a4949bf13d 253 Gene3D G3DSA:3.40.50.720 1 205 5.0E-31 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS13360 8be3730820b7a0d292f152a4949bf13d 253 PANTHER PTHR14194 1 244 6.9E-100 T 13-09-2016 THL1_RS13360 8be3730820b7a0d292f152a4949bf13d 253 SUPERFAMILY SSF51735 1 204 9.67E-34 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS13360 8be3730820b7a0d292f152a4949bf13d 253 Pfam PF13460 NAD(P)H-binding 7 173 1.2E-12 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS00975 2e884fea0ebc4af650cddd3a3ff54259 451 SUPERFAMILY SSF53383 8 443 1.63E-126 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS00975 2e884fea0ebc4af650cddd3a3ff54259 451 Gene3D G3DSA:3.90.1150.10 8 67 2.4E-49 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS00975 2e884fea0ebc4af650cddd3a3ff54259 451 Gene3D G3DSA:3.90.1150.10 343 444 2.4E-49 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS00975 2e884fea0ebc4af650cddd3a3ff54259 451 Gene3D G3DSA:3.40.640.10 68 342 3.2E-82 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS00975 2e884fea0ebc4af650cddd3a3ff54259 451 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 255 292 - T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS00975 2e884fea0ebc4af650cddd3a3ff54259 451 PANTHER PTHR11986:SF81 34 450 2.1E-169 T 13-09-2016 THL1_RS00975 2e884fea0ebc4af650cddd3a3ff54259 451 Pfam PF00202 Aminotransferase class-III 32 442 1.8E-103 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS00975 2e884fea0ebc4af650cddd3a3ff54259 451 PANTHER PTHR11986 34 450 2.1E-169 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS02625 685122f0bc6228aa53da8c395c6d11b8 341 PANTHER PTHR33540:SF1 24 338 8.4E-143 T 13-09-2016 THL1_RS02625 685122f0bc6228aa53da8c395c6d11b8 341 Gene3D G3DSA:3.90.1200.10 105 335 4.6E-69 T 13-09-2016 THL1_RS02625 685122f0bc6228aa53da8c395c6d11b8 341 Gene3D G3DSA:3.30.200.20 7 104 5.2E-32 T 13-09-2016 THL1_RS02625 685122f0bc6228aa53da8c395c6d11b8 341 SUPERFAMILY SSF56112 5 313 1.7E-56 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS02625 685122f0bc6228aa53da8c395c6d11b8 341 PANTHER PTHR33540 24 338 8.4E-143 T 13-09-2016 THL1_RS02625 685122f0bc6228aa53da8c395c6d11b8 341 Pfam PF01636 Phosphotransferase enzyme family 38 254 1.7E-32 T 13-09-2016 IPR002575 Aminoglycoside phosphotransferase THL1_RS23050 d4aa7ad113b35b506ad4dee18ada189c 242 Gene3D G3DSA:3.40.30.10 115 237 3.3E-41 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS23050 d4aa7ad113b35b506ad4dee18ada189c 242 Gene3D G3DSA:3.10.450.70 25 87 4.0E-22 T 13-09-2016 IPR009094 Disulphide bond isomerase, DsbC, N-terminal THL1_RS23050 d4aa7ad113b35b506ad4dee18ada189c 242 Pfam PF10411 Disulfide bond isomerase protein N-terminus 29 82 3.2E-16 T 13-09-2016 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal THL1_RS23050 d4aa7ad113b35b506ad4dee18ada189c 242 PANTHER PTHR35272 1 242 2.2E-90 T 13-09-2016 THL1_RS23050 d4aa7ad113b35b506ad4dee18ada189c 242 SUPERFAMILY SSF52833 101 236 2.36E-33 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS23050 d4aa7ad113b35b506ad4dee18ada189c 242 PANTHER PTHR35272:SF3 1 242 2.2E-90 T 13-09-2016 THL1_RS23050 d4aa7ad113b35b506ad4dee18ada189c 242 Pfam PF13098 Thioredoxin-like domain 119 237 1.0E-24 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS23050 d4aa7ad113b35b506ad4dee18ada189c 242 SUPERFAMILY SSF54423 25 86 1.44E-13 T 13-09-2016 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal THL1_RS28290 54af1eb79f541e18a827dd3023559a1d 220 Gene3D G3DSA:1.10.10.10 4 68 1.3E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS28290 54af1eb79f541e18a827dd3023559a1d 220 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 67 8.5E-18 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS28290 54af1eb79f541e18a827dd3023559a1d 220 SUPERFAMILY SSF46785 4 71 2.33E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS28290 54af1eb79f541e18a827dd3023559a1d 220 SUPERFAMILY SSF48008 74 209 4.45E-29 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS28290 54af1eb79f541e18a827dd3023559a1d 220 SMART SM00895 77 201 9.7E-22 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS28290 54af1eb79f541e18a827dd3023559a1d 220 PANTHER PTHR11751 1 93 2.1E-24 T 13-09-2016 THL1_RS28290 54af1eb79f541e18a827dd3023559a1d 220 PANTHER PTHR11751:SF283 1 93 2.1E-24 T 13-09-2016 THL1_RS28290 54af1eb79f541e18a827dd3023559a1d 220 Pfam PF07729 FCD domain 77 197 1.3E-27 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS28290 54af1eb79f541e18a827dd3023559a1d 220 Gene3D G3DSA:1.20.120.530 71 211 7.3E-29 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS28290 54af1eb79f541e18a827dd3023559a1d 220 SMART SM00345 9 67 3.8E-12 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS11360 b55bbd33ea3329534a78d759baca7162 123 Pfam PF13417 Glutathione S-transferase, N-terminal domain 45 121 4.9E-13 T 13-09-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THL1_RS11360 b55bbd33ea3329534a78d759baca7162 123 SUPERFAMILY SSF52833 43 121 9.72E-20 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS11360 b55bbd33ea3329534a78d759baca7162 123 Gene3D G3DSA:3.40.30.10 50 121 1.9E-23 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS27600 04219b0b72300c0b76893b9078af195e 263 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 104 124 - T 13-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THL1_RS27600 04219b0b72300c0b76893b9078af195e 263 PANTHER PTHR11941:SF86 2 260 2.5E-107 T 13-09-2016 THL1_RS27600 04219b0b72300c0b76893b9078af195e 263 PANTHER PTHR11941 2 260 2.5E-107 T 13-09-2016 THL1_RS27600 04219b0b72300c0b76893b9078af195e 263 Gene3D G3DSA:1.10.12.10 206 262 5.3E-14 T 13-09-2016 IPR014748 Crontonase, C-terminal THL1_RS27600 04219b0b72300c0b76893b9078af195e 263 Gene3D G3DSA:3.90.226.10 2 202 5.2E-55 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS27600 04219b0b72300c0b76893b9078af195e 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 263 2.6E-49 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS27600 04219b0b72300c0b76893b9078af195e 263 SUPERFAMILY SSF52096 1 262 1.01E-70 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS19260 5e3b276824f653b823d0bc22f8adda1a 288 PANTHER PTHR30007:SF4 1 285 9.6E-87 T 13-09-2016 THL1_RS19260 5e3b276824f653b823d0bc22f8adda1a 288 SUPERFAMILY SSF89550 168 279 3.53E-47 T 13-09-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 THL1_RS19260 5e3b276824f653b823d0bc22f8adda1a 288 SUPERFAMILY SSF89550 1 81 3.53E-47 T 13-09-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 THL1_RS19260 5e3b276824f653b823d0bc22f8adda1a 288 SMART SM00481 3 68 2.5E-17 T 13-09-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 THL1_RS19260 5e3b276824f653b823d0bc22f8adda1a 288 Pfam PF02811 PHP domain 4 70 2.5E-7 T 13-09-2016 IPR004013 PHP domain GO:0003824 THL1_RS19260 5e3b276824f653b823d0bc22f8adda1a 288 Gene3D G3DSA:3.20.20.140 1 86 2.6E-39 T 13-09-2016 THL1_RS19260 5e3b276824f653b823d0bc22f8adda1a 288 Gene3D G3DSA:3.20.20.140 160 267 2.6E-39 T 13-09-2016 THL1_RS19260 5e3b276824f653b823d0bc22f8adda1a 288 PANTHER PTHR30007 1 285 9.6E-87 T 13-09-2016 THL1_RS08845 37a91fe694e46dde8ec1c0fa03b470a3 216 Gene3D G3DSA:2.60.130.10 30 212 5.8E-47 T 13-09-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 THL1_RS08845 37a91fe694e46dde8ec1c0fa03b470a3 216 PANTHER PTHR33711 1 184 4.8E-40 T 13-09-2016 THL1_RS08845 37a91fe694e46dde8ec1c0fa03b470a3 216 Pfam PF00775 Dioxygenase 41 211 7.0E-33 T 13-09-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 THL1_RS08845 37a91fe694e46dde8ec1c0fa03b470a3 216 SUPERFAMILY SSF49482 21 213 6.41E-47 T 13-09-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 THL1_RS20200 c08cc8e89347f1abc5f217bb40909771 373 Gene3D G3DSA:3.40.47.10 206 371 2.5E-29 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20200 c08cc8e89347f1abc5f217bb40909771 373 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 150 217 1.9E-18 T 13-09-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 THL1_RS20200 c08cc8e89347f1abc5f217bb40909771 373 PANTHER PTHR34069:SF1 91 371 4.8E-205 T 13-09-2016 THL1_RS20200 c08cc8e89347f1abc5f217bb40909771 373 PANTHER PTHR34069:SF1 1 25 4.8E-205 T 13-09-2016 THL1_RS20200 c08cc8e89347f1abc5f217bb40909771 373 PANTHER PTHR34069:SF1 50 70 4.8E-205 T 13-09-2016 THL1_RS20200 c08cc8e89347f1abc5f217bb40909771 373 Gene3D G3DSA:3.40.47.10 2 205 3.9E-48 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20200 c08cc8e89347f1abc5f217bb40909771 373 PANTHER PTHR34069 1 25 4.8E-205 T 13-09-2016 THL1_RS20200 c08cc8e89347f1abc5f217bb40909771 373 PANTHER PTHR34069 50 70 4.8E-205 T 13-09-2016 THL1_RS20200 c08cc8e89347f1abc5f217bb40909771 373 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 282 371 1.2E-23 T 13-09-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 THL1_RS20200 c08cc8e89347f1abc5f217bb40909771 373 PANTHER PTHR34069 91 371 4.8E-205 T 13-09-2016 THL1_RS20200 c08cc8e89347f1abc5f217bb40909771 373 SUPERFAMILY SSF53901 3 372 2.49E-56 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17940 6515ee73d24fdb16b8618c597cb491c9 361 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 147 354 7.0E-35 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS17940 6515ee73d24fdb16b8618c597cb491c9 361 PANTHER PTHR30465:SF66 1 45 7.9E-214 T 13-09-2016 THL1_RS17940 6515ee73d24fdb16b8618c597cb491c9 361 PANTHER PTHR30465:SF66 65 356 7.9E-214 T 13-09-2016 THL1_RS17940 6515ee73d24fdb16b8618c597cb491c9 361 PANTHER PTHR30465 65 356 7.9E-214 T 13-09-2016 THL1_RS17940 6515ee73d24fdb16b8618c597cb491c9 361 SUPERFAMILY SSF161098 123 340 1.8E-13 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS17940 6515ee73d24fdb16b8618c597cb491c9 361 Gene3D G3DSA:1.10.3720.10 122 346 9.7E-14 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS17940 6515ee73d24fdb16b8618c597cb491c9 361 PANTHER PTHR30465 1 45 7.9E-214 T 13-09-2016 THL1_RS18670 ad3c286d3c151fe2b3c2d1d4a62a0144 175 Pfam PF02620 Uncharacterized ACR, COG1399 64 170 6.6E-18 T 13-09-2016 IPR003772 Protein of unknown function DUF177 THL1_RS18670 ad3c286d3c151fe2b3c2d1d4a62a0144 175 PANTHER PTHR38099 2 172 1.5E-55 T 13-09-2016 THL1_RS27780 8cd052e30d093e0aacae2b77f04f91ef 440 SUPERFAMILY SSF51905 354 430 8.42E-46 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27780 8cd052e30d093e0aacae2b77f04f91ef 440 SUPERFAMILY SSF51905 39 262 8.42E-46 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27780 8cd052e30d093e0aacae2b77f04f91ef 440 Gene3D G3DSA:3.50.50.60 25 128 6.8E-53 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27780 8cd052e30d093e0aacae2b77f04f91ef 440 Gene3D G3DSA:3.50.50.60 182 261 6.8E-53 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27780 8cd052e30d093e0aacae2b77f04f91ef 440 Gene3D G3DSA:3.50.50.60 354 400 6.8E-53 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27780 8cd052e30d093e0aacae2b77f04f91ef 440 PANTHER PTHR13847 1 435 1.1E-160 T 13-09-2016 THL1_RS27780 8cd052e30d093e0aacae2b77f04f91ef 440 Pfam PF01266 FAD dependent oxidoreductase 39 392 7.0E-51 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS27780 8cd052e30d093e0aacae2b77f04f91ef 440 PANTHER PTHR13847:SF196 1 435 1.1E-160 T 13-09-2016 THL1_RS13610 03150cb1c230e143f2425c4014b14f2e 247 SUPERFAMILY SSF88713 5 246 1.7E-94 T 13-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THL1_RS13610 03150cb1c230e143f2425c4014b14f2e 247 Pfam PF03746 LamB/YcsF family 6 245 1.3E-97 T 13-09-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF THL1_RS13610 03150cb1c230e143f2425c4014b14f2e 247 PANTHER PTHR30292:SF0 1 247 1.7E-123 T 13-09-2016 THL1_RS13610 03150cb1c230e143f2425c4014b14f2e 247 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 247 43.283 T 13-09-2016 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF THL1_RS13610 03150cb1c230e143f2425c4014b14f2e 247 PANTHER PTHR30292 1 247 1.7E-123 T 13-09-2016 THL1_RS07845 40f4445729d83c2c2ee0ea081515abc5 493 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS07845 40f4445729d83c2c2ee0ea081515abc5 493 Gene3D G3DSA:3.40.605.10 6 267 1.9E-101 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS07845 40f4445729d83c2c2ee0ea081515abc5 493 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 281 292 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS07845 40f4445729d83c2c2ee0ea081515abc5 493 PANTHER PTHR11699:SF187 6 491 6.0E-251 T 13-09-2016 THL1_RS07845 40f4445729d83c2c2ee0ea081515abc5 493 PANTHER PTHR11699 6 491 6.0E-251 T 13-09-2016 THL1_RS07845 40f4445729d83c2c2ee0ea081515abc5 493 SUPERFAMILY SSF53720 5 480 6.41E-173 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS07845 40f4445729d83c2c2ee0ea081515abc5 493 Pfam PF00171 Aldehyde dehydrogenase family 13 479 1.4E-176 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS07845 40f4445729d83c2c2ee0ea081515abc5 493 Gene3D G3DSA:3.40.309.10 268 454 1.9E-72 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS24905 3390769a25a7546011027634d61858b6 135 PANTHER PTHR34873:SF2 1 134 3.6E-27 T 13-09-2016 THL1_RS24905 3390769a25a7546011027634d61858b6 135 PANTHER PTHR34873 1 134 3.6E-27 T 13-09-2016 THL1_RS24905 3390769a25a7546011027634d61858b6 135 SUPERFAMILY SSF143100 2 66 2.49E-20 T 13-09-2016 THL1_RS24905 3390769a25a7546011027634d61858b6 135 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 128 1.8E-48 T 13-09-2016 IPR031807 HicB-like antitoxin of toxin-antitoxin system THL1_RS18625 c54b9f3a4b09f1e2963e07c832ac28e3 97 Pfam PF02223 Thymidylate kinase 8 97 2.4E-27 T 13-09-2016 THL1_RS18625 c54b9f3a4b09f1e2963e07c832ac28e3 97 SUPERFAMILY SSF52540 3 97 6.03E-29 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18625 c54b9f3a4b09f1e2963e07c832ac28e3 97 Gene3D G3DSA:3.40.50.300 3 97 9.6E-37 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18625 c54b9f3a4b09f1e2963e07c832ac28e3 97 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 97 2.4E-29 T 13-09-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 THL1_RS18625 c54b9f3a4b09f1e2963e07c832ac28e3 97 PANTHER PTHR10344 3 97 8.0E-34 T 13-09-2016 THL1_RS19320 20c32f38ee72099a465d649f34a0369a 457 SUPERFAMILY SSF55073 215 403 1.51E-59 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS19320 20c32f38ee72099a465d649f34a0369a 457 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 219 401 9.3E-39 T 13-09-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 THL1_RS19320 20c32f38ee72099a465d649f34a0369a 457 SMART SM00044 182 392 4.0E-32 T 13-09-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 THL1_RS19320 20c32f38ee72099a465d649f34a0369a 457 PANTHER PTHR11920 424 441 1.2E-110 T 13-09-2016 THL1_RS19320 20c32f38ee72099a465d649f34a0369a 457 PANTHER PTHR11920 172 408 1.2E-110 T 13-09-2016 THL1_RS19320 20c32f38ee72099a465d649f34a0369a 457 Gene3D G3DSA:3.30.70.1230 217 403 2.0E-54 T 13-09-2016 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 THL1_RS19320 20c32f38ee72099a465d649f34a0369a 457 Pfam PF05230 MASE2 domain 16 102 8.5E-25 T 13-09-2016 IPR007894 MASE2 THL1_RS19320 20c32f38ee72099a465d649f34a0369a 457 PANTHER PTHR11920:SF341 424 441 1.2E-110 T 13-09-2016 THL1_RS19320 20c32f38ee72099a465d649f34a0369a 457 PANTHER PTHR11920:SF341 172 408 1.2E-110 T 13-09-2016 THL1_RS16430 795b7e6e3eac3191b6b6faf69e761f33 294 SUPERFAMILY SSF103481 42 134 3.79E-11 T 13-09-2016 THL1_RS16430 795b7e6e3eac3191b6b6faf69e761f33 294 PANTHER PTHR32322:SF9 4 283 1.1E-80 T 13-09-2016 THL1_RS16430 795b7e6e3eac3191b6b6faf69e761f33 294 PANTHER PTHR32322 4 283 1.1E-80 T 13-09-2016 THL1_RS16430 795b7e6e3eac3191b6b6faf69e761f33 294 Pfam PF00892 EamA-like transporter family 6 130 2.4E-12 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS16430 795b7e6e3eac3191b6b6faf69e761f33 294 Pfam PF00892 EamA-like transporter family 141 280 5.6E-17 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS16430 795b7e6e3eac3191b6b6faf69e761f33 294 SUPERFAMILY SSF103481 203 283 3.4E-11 T 13-09-2016 THL1_RS26990 39d8c39117964aaaf5e45da329c4f491 457 SMART SM00382 170 313 5.8E-11 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS26990 39d8c39117964aaaf5e45da329c4f491 457 Gene3D G3DSA:3.40.50.2300 8 131 2.3E-36 T 13-09-2016 THL1_RS26990 39d8c39117964aaaf5e45da329c4f491 457 Pfam PF00158 Sigma-54 interaction domain 150 316 2.0E-66 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS26990 39d8c39117964aaaf5e45da329c4f491 457 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 236 251 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS26990 39d8c39117964aaaf5e45da329c4f491 457 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 363 372 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS26990 39d8c39117964aaaf5e45da329c4f491 457 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 174 187 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS26990 39d8c39117964aaaf5e45da329c4f491 457 Gene3D G3DSA:3.40.50.300 149 322 5.3E-56 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26990 39d8c39117964aaaf5e45da329c4f491 457 SMART SM00448 9 120 9.7E-33 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS26990 39d8c39117964aaaf5e45da329c4f491 457 Gene3D G3DSA:1.10.10.60 373 445 5.0E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS26990 39d8c39117964aaaf5e45da329c4f491 457 SUPERFAMILY SSF52172 10 195 1.1E-44 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS26990 39d8c39117964aaaf5e45da329c4f491 457 Pfam PF02954 Bacterial regulatory protein, Fis family 403 443 1.2E-4 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS26990 39d8c39117964aaaf5e45da329c4f491 457 Gene3D G3DSA:1.10.8.60 323 372 8.5E-18 T 13-09-2016 THL1_RS26990 39d8c39117964aaaf5e45da329c4f491 457 Pfam PF00072 Response regulator receiver domain 11 120 8.2E-31 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS26990 39d8c39117964aaaf5e45da329c4f491 457 PANTHER PTHR32071 1 454 6.1E-256 T 13-09-2016 THL1_RS26990 39d8c39117964aaaf5e45da329c4f491 457 SUPERFAMILY SSF46689 396 446 1.04E-7 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS26990 39d8c39117964aaaf5e45da329c4f491 457 PANTHER PTHR32071:SF40 1 454 6.1E-256 T 13-09-2016 THL1_RS26990 39d8c39117964aaaf5e45da329c4f491 457 SUPERFAMILY SSF52540 150 379 5.15E-66 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10910 2715ef0cd6dd3ac8c26755ef0cd3ea55 249 PANTHER PTHR31881:SF3 7 246 4.1E-127 T 13-09-2016 THL1_RS10910 2715ef0cd6dd3ac8c26755ef0cd3ea55 249 PANTHER PTHR31881 7 246 4.1E-127 T 13-09-2016 THL1_RS10910 2715ef0cd6dd3ac8c26755ef0cd3ea55 249 Pfam PF04654 Protein of unknown function, DUF599 17 228 2.2E-63 T 13-09-2016 IPR006747 Protein of unknown function DUF599 THL1_RS22465 2ca1d38debcc8f443e0960de72597eb4 170 SUPERFAMILY SSF142433 6 161 2.48E-52 T 13-09-2016 IPR008136 CinA, C-terminal THL1_RS22465 2ca1d38debcc8f443e0960de72597eb4 170 PANTHER PTHR13939 3 170 1.8E-69 T 13-09-2016 THL1_RS22465 2ca1d38debcc8f443e0960de72597eb4 170 Pfam PF02464 Competence-damaged protein 11 160 5.2E-56 T 13-09-2016 IPR008136 CinA, C-terminal THL1_RS22465 2ca1d38debcc8f443e0960de72597eb4 170 Gene3D G3DSA:3.90.950.20 4 162 1.1E-54 T 13-09-2016 IPR008136 CinA, C-terminal THL1_RS22465 2ca1d38debcc8f443e0960de72597eb4 170 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 15 159 1.7E-44 T 13-09-2016 IPR008136 CinA, C-terminal THL1_RS09795 733a081112a51a9390a5d7517333caab 94 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 1.4E-18 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS09795 733a081112a51a9390a5d7517333caab 94 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 1.4E-18 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS09795 733a081112a51a9390a5d7517333caab 94 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 1.4E-18 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS09795 733a081112a51a9390a5d7517333caab 94 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 94 4.9E-53 T 13-09-2016 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 THL1_RS09795 733a081112a51a9390a5d7517333caab 94 Pfam PF00216 Bacterial DNA-binding protein 1 91 2.5E-29 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS09795 733a081112a51a9390a5d7517333caab 94 Gene3D G3DSA:4.10.520.10 1 92 1.8E-34 T 13-09-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THL1_RS09795 733a081112a51a9390a5d7517333caab 94 PANTHER PTHR33175 1 94 9.9E-48 T 13-09-2016 THL1_RS09795 733a081112a51a9390a5d7517333caab 94 PANTHER PTHR33175:SF5 1 94 9.9E-48 T 13-09-2016 THL1_RS09795 733a081112a51a9390a5d7517333caab 94 SMART SM00411 1 91 1.2E-42 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS09795 733a081112a51a9390a5d7517333caab 94 SUPERFAMILY SSF47729 1 92 5.45E-31 T 13-09-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THL1_RS09795 733a081112a51a9390a5d7517333caab 94 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 13-09-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 THL1_RS09795 733a081112a51a9390a5d7517333caab 94 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 29.517 T 13-09-2016 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 THL1_RS26110 5920d5ba306407bff78abb3f18e8a6b3 161 SUPERFAMILY SSF51161 12 153 1.74E-43 T 13-09-2016 IPR011004 Trimeric LpxA-like THL1_RS26110 5920d5ba306407bff78abb3f18e8a6b3 161 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 99 133 3.0E-8 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS26110 5920d5ba306407bff78abb3f18e8a6b3 161 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 46 7.1E-8 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS26110 5920d5ba306407bff78abb3f18e8a6b3 161 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 49 82 2.4E-4 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS26110 5920d5ba306407bff78abb3f18e8a6b3 161 Gene3D G3DSA:2.160.10.10 12 158 7.4E-46 T 13-09-2016 THL1_RS26110 5920d5ba306407bff78abb3f18e8a6b3 161 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 107 135 - T 13-09-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 THL1_RS26110 5920d5ba306407bff78abb3f18e8a6b3 161 PANTHER PTHR23416 15 160 2.8E-43 T 13-09-2016 THL1_RS26110 5920d5ba306407bff78abb3f18e8a6b3 161 PANTHER PTHR23416:SF53 15 160 2.8E-43 T 13-09-2016 THL1_RS22590 09d0df0ccf55bc89d349e0dc332c2ded 353 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 11 332 3.1E-117 T 13-09-2016 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 UniPathway: UPA00973 THL1_RS22590 09d0df0ccf55bc89d349e0dc332c2ded 353 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 26 92 5.7E-24 T 13-09-2016 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 UniPathway: UPA00973 THL1_RS22590 09d0df0ccf55bc89d349e0dc332c2ded 353 SUPERFAMILY SSF51161 35 320 9.89E-82 T 13-09-2016 IPR011004 Trimeric LpxA-like THL1_RS22590 09d0df0ccf55bc89d349e0dc332c2ded 353 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 149 183 8.9E-8 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS22590 09d0df0ccf55bc89d349e0dc332c2ded 353 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 225 260 2.4E-5 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS22590 09d0df0ccf55bc89d349e0dc332c2ded 353 PANTHER PTHR22572 101 298 4.9E-50 T 13-09-2016 THL1_RS22590 09d0df0ccf55bc89d349e0dc332c2ded 353 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 12 329 36.286 T 13-09-2016 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 UniPathway: UPA00973 THL1_RS22590 09d0df0ccf55bc89d349e0dc332c2ded 353 Gene3D G3DSA:2.160.10.10 148 308 2.9E-36 T 13-09-2016 THL1_RS22590 09d0df0ccf55bc89d349e0dc332c2ded 353 Gene3D G3DSA:2.160.10.10 103 147 1.8E-10 T 13-09-2016 THL1_RS22590 09d0df0ccf55bc89d349e0dc332c2ded 353 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 109 137 - T 13-09-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 THL1_RS22590 09d0df0ccf55bc89d349e0dc332c2ded 353 PANTHER PTHR22572:SF117 101 298 4.9E-50 T 13-09-2016 THL1_RS24130 62d283fa488f51e36466ae22249fce64 207 Pfam PF04403 Paraquat-inducible protein A 46 199 1.4E-54 T 13-09-2016 IPR007498 Paraquat-inducible protein A THL1_RS24130 62d283fa488f51e36466ae22249fce64 207 PANTHER PTHR30462:SF1 8 204 2.6E-57 T 13-09-2016 THL1_RS24130 62d283fa488f51e36466ae22249fce64 207 PANTHER PTHR30462 8 204 2.6E-57 T 13-09-2016 THL1_RS10420 7f3d712de252fdb590f42b2616c10c34 308 PANTHER PTHR30212:SF3 1 299 1.5E-82 T 13-09-2016 THL1_RS10420 7f3d712de252fdb590f42b2616c10c34 308 Gene3D G3DSA:2.30.110.10 167 257 1.0E-5 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS10420 7f3d712de252fdb590f42b2616c10c34 308 Gene3D G3DSA:2.30.110.10 27 118 4.6E-4 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS10420 7f3d712de252fdb590f42b2616c10c34 308 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 34 119 2.2E-5 T 13-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 THL1_RS10420 7f3d712de252fdb590f42b2616c10c34 308 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 165 258 2.8E-10 T 13-09-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 THL1_RS10420 7f3d712de252fdb590f42b2616c10c34 308 SUPERFAMILY SSF50475 167 259 2.72E-6 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS10420 7f3d712de252fdb590f42b2616c10c34 308 PANTHER PTHR30212 1 299 1.5E-82 T 13-09-2016 THL1_RS26745 37dd3fd4120c79b6c67bd6e727aca6c1 245 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 239 35.92 T 13-09-2016 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16|UniPathway: UPA00031 THL1_RS26745 37dd3fd4120c79b6c67bd6e727aca6c1 245 Pfam PF00977 Histidine biosynthesis protein 3 231 1.3E-78 T 13-09-2016 IPR006062 Histidine biosynthesis GO:0000105 THL1_RS26745 37dd3fd4120c79b6c67bd6e727aca6c1 245 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 235 1.5E-78 T 13-09-2016 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16|UniPathway: UPA00031 THL1_RS26745 37dd3fd4120c79b6c67bd6e727aca6c1 245 PANTHER PTHR21235:SF15 1 239 7.0E-106 T 13-09-2016 THL1_RS26745 37dd3fd4120c79b6c67bd6e727aca6c1 245 SUPERFAMILY SSF51366 1 240 5.34E-77 T 13-09-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 THL1_RS26745 37dd3fd4120c79b6c67bd6e727aca6c1 245 PANTHER PTHR21235 1 239 7.0E-106 T 13-09-2016 THL1_RS26745 37dd3fd4120c79b6c67bd6e727aca6c1 245 Gene3D G3DSA:3.20.20.70 1 240 8.7E-89 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS03930 a81c7dd82c7626faa380d683258e0c7c 80 Pfam PF02609 Exonuclease VII small subunit 10 61 2.0E-20 T 13-09-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 THL1_RS03930 a81c7dd82c7626faa380d683258e0c7c 80 Gene3D G3DSA:1.10.287.1040 4 77 2.6E-27 T 13-09-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 THL1_RS03930 a81c7dd82c7626faa380d683258e0c7c 80 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 9 64 1.9E-22 T 13-09-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 THL1_RS03930 a81c7dd82c7626faa380d683258e0c7c 80 PANTHER PTHR34137 1 79 6.4E-23 T 13-09-2016 THL1_RS03930 a81c7dd82c7626faa380d683258e0c7c 80 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 49 2.0E-7 T 13-09-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 THL1_RS03930 a81c7dd82c7626faa380d683258e0c7c 80 PIRSF PIRSF006488 1 80 1.7E-22 T 13-09-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 THL1_RS03930 a81c7dd82c7626faa380d683258e0c7c 80 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 9 69 15.826 T 13-09-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 THL1_RS03930 a81c7dd82c7626faa380d683258e0c7c 80 SUPERFAMILY SSF116842 3 68 7.72E-21 T 13-09-2016 THL1_RS19380 55eaef6199978f75eeb5f8e1bbcb8570 267 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 232 244 3.1E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS19380 55eaef6199978f75eeb5f8e1bbcb8570 267 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 216 232 3.1E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS19380 55eaef6199978f75eeb5f8e1bbcb8570 267 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 202 216 3.1E-11 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS19380 55eaef6199978f75eeb5f8e1bbcb8570 267 Gene3D G3DSA:1.10.10.10 201 258 1.5E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19380 55eaef6199978f75eeb5f8e1bbcb8570 267 PANTHER PTHR26402 202 261 9.8E-32 T 13-09-2016 THL1_RS19380 55eaef6199978f75eeb5f8e1bbcb8570 267 SMART SM00421 199 256 4.6E-20 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS19380 55eaef6199978f75eeb5f8e1bbcb8570 267 SUPERFAMILY SSF46894 191 258 4.76E-17 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS19380 55eaef6199978f75eeb5f8e1bbcb8570 267 PANTHER PTHR26402:SF572 202 261 9.8E-32 T 13-09-2016 THL1_RS19380 55eaef6199978f75eeb5f8e1bbcb8570 267 Pfam PF00196 Bacterial regulatory proteins, luxR family 201 254 5.9E-16 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS22390 0f34240a2cd5d36624f2a757367b3a67 256 Gene3D G3DSA:3.40.50.720 4 256 8.3E-82 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS22390 0f34240a2cd5d36624f2a757367b3a67 256 SUPERFAMILY SSF51735 4 256 3.46E-76 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS22390 0f34240a2cd5d36624f2a757367b3a67 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 255 3.3E-55 T 13-09-2016 THL1_RS22390 0f34240a2cd5d36624f2a757367b3a67 256 PANTHER PTHR24322:SF513 162 193 6.6E-50 T 13-09-2016 THL1_RS22390 0f34240a2cd5d36624f2a757367b3a67 256 PANTHER PTHR24322:SF513 14 145 6.6E-50 T 13-09-2016 THL1_RS22390 0f34240a2cd5d36624f2a757367b3a67 256 PANTHER PTHR24322 162 193 6.6E-50 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22390 0f34240a2cd5d36624f2a757367b3a67 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.4E-8 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22390 0f34240a2cd5d36624f2a757367b3a67 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 2.4E-8 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22390 0f34240a2cd5d36624f2a757367b3a67 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 2.4E-8 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22390 0f34240a2cd5d36624f2a757367b3a67 256 PANTHER PTHR24322 14 145 6.6E-50 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22390 0f34240a2cd5d36624f2a757367b3a67 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.7E-30 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22390 0f34240a2cd5d36624f2a757367b3a67 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 1.7E-30 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22390 0f34240a2cd5d36624f2a757367b3a67 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.7E-30 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22390 0f34240a2cd5d36624f2a757367b3a67 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.7E-30 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22390 0f34240a2cd5d36624f2a757367b3a67 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.7E-30 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS22390 0f34240a2cd5d36624f2a757367b3a67 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 1.7E-30 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS24900 b4250dbd6e153613345e374eab7b36c8 113 Pfam PF08274 PhnA Zinc-Ribbon 3 32 2.7E-17 T 13-09-2016 IPR013987 PhnA protein, N-terminal THL1_RS24900 b4250dbd6e153613345e374eab7b36c8 113 Gene3D G3DSA:2.20.25.10 2 40 8.9E-23 T 13-09-2016 THL1_RS24900 b4250dbd6e153613345e374eab7b36c8 113 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 4 112 5.4E-50 T 13-09-2016 IPR004624 PhnA protein THL1_RS24900 b4250dbd6e153613345e374eab7b36c8 113 Pfam PF03831 PhnA domain 46 113 6.7E-33 T 13-09-2016 IPR013988 PhnA protein, C-terminal THL1_RS24900 b4250dbd6e153613345e374eab7b36c8 113 SUPERFAMILY SSF57783 3 36 6.46E-15 T 13-09-2016 THL1_RS24900 b4250dbd6e153613345e374eab7b36c8 113 PANTHER PTHR30305 2 113 4.9E-83 T 13-09-2016 THL1_RS24900 b4250dbd6e153613345e374eab7b36c8 113 SUPERFAMILY SSF82057 42 113 7.32E-29 T 13-09-2016 THL1_RS24900 b4250dbd6e153613345e374eab7b36c8 113 Gene3D G3DSA:2.30.30.40 45 113 1.1E-36 T 13-09-2016 THL1_RS03920 e8b959fd2dd3aa0c22982bccb07fb01a 103 Pfam PF09907 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system 23 95 6.0E-31 T 13-09-2016 IPR018669 Toxin-antitoxin system, toxin component, HigB, putative GO:0016788 THL1_RS23820 335d06da49684b503d4d26938a819db1 60 PIRSF PIRSF037225 1 60 1.9E-25 T 13-09-2016 IPR017143 Uncharacterised conserved protein UCP037225 THL1_RS23820 335d06da49684b503d4d26938a819db1 60 Pfam PF14255 Cysteine-rich CPXCG 7 56 1.0E-22 T 13-09-2016 IPR025990 Cysteine-rich CPXCG protein THL1_RS27440 92fe7443458228cd37267951f4c306e3 256 Gene3D G3DSA:3.40.50.10090 133 251 7.4E-9 T 13-09-2016 THL1_RS27440 92fe7443458228cd37267951f4c306e3 256 Gene3D G3DSA:3.40.50.10090 2 119 3.5E-9 T 13-09-2016 THL1_RS27440 92fe7443458228cd37267951f4c306e3 256 Pfam PF02602 Uroporphyrinogen-III synthase HemD 17 245 8.3E-33 T 13-09-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27440 92fe7443458228cd37267951f4c306e3 256 PANTHER PTHR38042:SF1 1 256 8.8E-66 T 13-09-2016 THL1_RS27440 92fe7443458228cd37267951f4c306e3 256 PANTHER PTHR38042 1 256 8.8E-66 T 13-09-2016 THL1_RS27440 92fe7443458228cd37267951f4c306e3 256 SUPERFAMILY SSF69618 3 251 3.01E-51 T 13-09-2016 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS26155 17363b295bd9d9abe974968089bcd69d 245 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 155 167 - T 13-09-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 THL1_RS26155 17363b295bd9d9abe974968089bcd69d 245 Gene3D G3DSA:1.10.510.10 121 163 2.2E-9 T 13-09-2016 THL1_RS26155 17363b295bd9d9abe974968089bcd69d 245 Gene3D G3DSA:3.90.1200.10 164 223 8.1E-5 T 13-09-2016 THL1_RS26155 17363b295bd9d9abe974968089bcd69d 245 SUPERFAMILY SSF56112 11 187 8.23E-17 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS26155 17363b295bd9d9abe974968089bcd69d 245 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 40 177 6.3E-17 T 13-09-2016 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 SMART SM01018 658 741 2.1E-40 T 13-09-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 Gene3D G3DSA:3.10.196.10 961 1229 1.7E-110 T 13-09-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 SUPERFAMILY SSF82282 11 402 2.49E-116 T 13-09-2016 IPR003726 Homocysteine-binding domain THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 PANTHER PTHR21091 1 405 2.7E-177 T 13-09-2016 THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 Gene3D G3DSA:3.20.20.330 6 366 9.0E-128 T 13-09-2016 IPR003726 Homocysteine-binding domain THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 942 1212 9.0E-125 T 13-09-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 PIRSF PIRSF000381 4 1199 0.0 T 13-09-2016 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 SUPERFAMILY SSF52242 744 896 1.96E-45 T 13-09-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 Pfam PF02310 B12 binding domain 750 843 1.2E-18 T 13-09-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 TIGRFAM TIGR02082 metH: methionine synthase 15 1196 0.0 T 13-09-2016 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0008898|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 Pfam PF02574 Homocysteine S-methyltransferase 20 328 3.3E-91 T 13-09-2016 IPR003726 Homocysteine-binding domain THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 Gene3D G3DSA:1.10.1240.10 651 738 1.5E-37 T 13-09-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 SUPERFAMILY SSF51717 359 631 5.76E-89 T 13-09-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 PANTHER PTHR21091:SF111 1 405 2.7E-177 T 13-09-2016 THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 SUPERFAMILY SSF56507 906 1229 1.22E-126 T 13-09-2016 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0005622|GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00051 THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 Gene3D G3DSA:3.20.20.20 367 639 1.0E-113 T 13-09-2016 IPR000489 Pterin-binding domain GO:0042558 THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 Gene3D G3DSA:3.40.50.280 747 897 2.8E-63 T 13-09-2016 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 SUPERFAMILY SSF47644 653 740 2.75E-28 T 13-09-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 Pfam PF00809 Pterin binding enzyme 363 601 2.8E-57 T 13-09-2016 IPR000489 Pterin-binding domain GO:0042558 THL1_RS17745 daa60bbbd44640a614e8490da1e78edc 1230 Pfam PF02607 B12 binding domain 660 733 1.2E-24 T 13-09-2016 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain THL1_RS17640 2500ddafe6a8dc13a463da15eba0a1bc 83 SUPERFAMILY SSF46785 7 54 1.47E-6 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS17640 2500ddafe6a8dc13a463da15eba0a1bc 83 Pfam PF01726 LexA DNA binding domain 8 54 2.7E-8 T 13-09-2016 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 THL1_RS17640 2500ddafe6a8dc13a463da15eba0a1bc 83 Gene3D G3DSA:1.10.10.10 7 54 1.3E-8 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS06380 2fc0240e7274ca8e7cf114ff9b5c7fdd 312 SMART SM00100 18 137 9.1E-8 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS06380 2fc0240e7274ca8e7cf114ff9b5c7fdd 312 Pfam PF00027 Cyclic nucleotide-binding domain 39 121 2.8E-14 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS06380 2fc0240e7274ca8e7cf114ff9b5c7fdd 312 SMART SM00267 140 311 6.8E-38 T 13-09-2016 IPR000160 GGDEF domain THL1_RS06380 2fc0240e7274ca8e7cf114ff9b5c7fdd 312 SUPERFAMILY SSF55073 156 310 4.0E-46 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS06380 2fc0240e7274ca8e7cf114ff9b5c7fdd 312 Gene3D G3DSA:3.30.70.270 153 310 1.1E-47 T 13-09-2016 THL1_RS06380 2fc0240e7274ca8e7cf114ff9b5c7fdd 312 PANTHER PTHR10799 13 115 5.9E-25 T 13-09-2016 THL1_RS06380 2fc0240e7274ca8e7cf114ff9b5c7fdd 312 Pfam PF00990 Diguanylate cyclase, GGDEF domain 151 309 8.5E-41 T 13-09-2016 IPR000160 GGDEF domain THL1_RS06380 2fc0240e7274ca8e7cf114ff9b5c7fdd 312 SUPERFAMILY SSF51206 9 138 4.32E-24 T 13-09-2016 IPR018490 Cyclic nucleotide-binding-like THL1_RS06380 2fc0240e7274ca8e7cf114ff9b5c7fdd 312 PANTHER PTHR10799 184 310 5.9E-25 T 13-09-2016 THL1_RS06380 2fc0240e7274ca8e7cf114ff9b5c7fdd 312 Gene3D G3DSA:2.60.120.10 7 140 4.6E-25 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS06380 2fc0240e7274ca8e7cf114ff9b5c7fdd 312 PANTHER PTHR10799:SF750 184 310 5.9E-25 T 13-09-2016 THL1_RS06380 2fc0240e7274ca8e7cf114ff9b5c7fdd 312 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 148 310 9.9E-45 T 13-09-2016 IPR000160 GGDEF domain THL1_RS06380 2fc0240e7274ca8e7cf114ff9b5c7fdd 312 PANTHER PTHR10799:SF750 13 115 5.9E-25 T 13-09-2016 THL1_RS08540 e344f823306e3dd42ebc32b37bdde1e7 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 71 89 4.0E-49 T 13-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THL1_RS08540 e344f823306e3dd42ebc32b37bdde1e7 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 258 276 4.0E-49 T 13-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THL1_RS08540 e344f823306e3dd42ebc32b37bdde1e7 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 281 294 4.0E-49 T 13-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THL1_RS08540 e344f823306e3dd42ebc32b37bdde1e7 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 30 46 4.0E-49 T 13-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THL1_RS08540 e344f823306e3dd42ebc32b37bdde1e7 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 52 68 4.0E-49 T 13-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THL1_RS08540 e344f823306e3dd42ebc32b37bdde1e7 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 92 102 4.0E-49 T 13-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THL1_RS08540 e344f823306e3dd42ebc32b37bdde1e7 373 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 333 348 4.0E-49 T 13-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THL1_RS08540 e344f823306e3dd42ebc32b37bdde1e7 373 Gene3D G3DSA:3.40.50.2300 28 228 5.4E-67 T 13-09-2016 THL1_RS08540 e344f823306e3dd42ebc32b37bdde1e7 373 PANTHER PTHR30483 7 366 2.7E-158 T 13-09-2016 THL1_RS08540 e344f823306e3dd42ebc32b37bdde1e7 373 Pfam PF13458 Periplasmic binding protein 29 367 1.3E-64 T 13-09-2016 IPR028081 Leucine-binding protein domain THL1_RS08540 e344f823306e3dd42ebc32b37bdde1e7 373 PANTHER PTHR30483:SF12 7 366 2.7E-158 T 13-09-2016 THL1_RS08540 e344f823306e3dd42ebc32b37bdde1e7 373 SUPERFAMILY SSF53822 28 367 2.03E-98 T 13-09-2016 IPR028082 Periplasmic binding protein-like I THL1_RS09685 c279a75d5aa2bdf55fa2f5dd6ba6785a 337 PIRSF PIRSF017082 1 337 4.1E-77 T 13-09-2016 IPR005064 Bordetella uptake gene GO:0030288 THL1_RS09685 c279a75d5aa2bdf55fa2f5dd6ba6785a 337 PANTHER PTHR30349:SF7 6 325 2.9E-160 T 13-09-2016 THL1_RS09685 c279a75d5aa2bdf55fa2f5dd6ba6785a 337 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 68 332 3.0E-16 T 13-09-2016 IPR005064 Bordetella uptake gene GO:0030288 THL1_RS09685 c279a75d5aa2bdf55fa2f5dd6ba6785a 337 PANTHER PTHR30349 6 325 2.9E-160 T 13-09-2016 THL1_RS01900 f3f0841484fb37433d687e030abb22dd 201 Gene3D G3DSA:1.20.1050.10 90 188 5.1E-33 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS01900 f3f0841484fb37433d687e030abb22dd 201 Gene3D G3DSA:3.40.30.10 1 89 5.0E-25 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS01900 f3f0841484fb37433d687e030abb22dd 201 PANTHER PTHR11260:SF154 1 195 7.5E-76 T 13-09-2016 THL1_RS01900 f3f0841484fb37433d687e030abb22dd 201 PANTHER PTHR11260 1 195 7.5E-76 T 13-09-2016 THL1_RS01900 f3f0841484fb37433d687e030abb22dd 201 Pfam PF14497 Glutathione S-transferase, C-terminal domain 119 196 4.5E-8 T 13-09-2016 IPR004046 Glutathione S-transferase, C-terminal THL1_RS01900 f3f0841484fb37433d687e030abb22dd 201 SUPERFAMILY SSF52833 1 78 1.33E-17 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS01900 f3f0841484fb37433d687e030abb22dd 201 SUPERFAMILY SSF47616 81 199 8.07E-30 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS01900 f3f0841484fb37433d687e030abb22dd 201 Pfam PF13417 Glutathione S-transferase, N-terminal domain 13 78 1.2E-8 T 13-09-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THL1_RS05400 db7a71ae66bc91bb83eab488e1561457 265 PANTHER PTHR30188 2 263 7.6E-122 T 13-09-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 THL1_RS05400 db7a71ae66bc91bb83eab488e1561457 265 PANTHER PTHR30188:SF4 2 263 7.6E-122 T 13-09-2016 THL1_RS05400 db7a71ae66bc91bb83eab488e1561457 265 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 11 262 1.3E-93 T 13-09-2016 IPR003453 ABC transport permease subunit MlaE, Proteobacteria THL1_RS05400 db7a71ae66bc91bb83eab488e1561457 265 Pfam PF02405 Permease MlaE 49 260 2.2E-76 T 13-09-2016 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 THL1_RS19015 cb615be881bafd15e1a4f103fe46f792 209 Gene3D G3DSA:3.40.50.150 18 207 2.0E-32 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS19015 cb615be881bafd15e1a4f103fe46f792 209 Pfam PF13649 Methyltransferase domain 55 143 1.9E-16 T 13-09-2016 THL1_RS19015 cb615be881bafd15e1a4f103fe46f792 209 PANTHER PTHR10108 17 201 6.0E-19 T 13-09-2016 THL1_RS19015 cb615be881bafd15e1a4f103fe46f792 209 SUPERFAMILY SSF53335 18 204 1.96E-36 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS07275 07df9d7019e52150356cf92740e8ef3e 97 Pfam PF07045 Domain of unknown function (DUF1330) 2 95 4.8E-37 T 13-09-2016 IPR010753 Domain of unknown function DUF1330 THL1_RS07275 07df9d7019e52150356cf92740e8ef3e 97 Gene3D G3DSA:3.30.70.900 1 95 1.7E-36 T 13-09-2016 THL1_RS07275 07df9d7019e52150356cf92740e8ef3e 97 PANTHER PTHR41521 1 97 3.5E-23 T 13-09-2016 THL1_RS07275 07df9d7019e52150356cf92740e8ef3e 97 SUPERFAMILY SSF54909 1 95 2.2E-31 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 SUPERFAMILY SSF48029 12 122 3.27E-24 T 13-09-2016 IPR011002 Flagellar motor switch protein FliG, alpha-helical THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 PANTHER PTHR30534:SF0 1 338 5.3E-114 T 13-09-2016 THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 PIRSF PIRSF003161 4 338 7.9E-119 T 13-09-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 5 336 9.2E-103 T 13-09-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 Gene3D G3DSA:1.10.220.30 109 194 1.4E-28 T 13-09-2016 IPR011002 Flagellar motor switch protein FliG, alpha-helical THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 Gene3D G3DSA:1.10.220.30 12 76 1.6E-16 T 13-09-2016 IPR011002 Flagellar motor switch protein FliG, alpha-helical THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 Pfam PF01706 FliG C-terminal domain 223 329 4.5E-41 T 13-09-2016 IPR023087 Flagellar motor switch protein FliG, C-terminal THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 Pfam PF14842 FliG N-terminal domain 9 108 8.7E-34 T 13-09-2016 IPR028263 Flagellar motor switch protein FliG, N-terminal domain THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 SUPERFAMILY SSF48029 119 330 1.57E-69 T 13-09-2016 IPR011002 Flagellar motor switch protein FliG, alpha-helical THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 PANTHER PTHR30534 1 338 5.3E-114 T 13-09-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 Pfam PF14841 FliG middle domain 120 193 5.2E-24 T 13-09-2016 IPR032779 Flagellar motor switch protein FliG, middle domain THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 Gene3D G3DSA:1.10.220.30 200 338 2.4E-43 T 13-09-2016 IPR011002 Flagellar motor switch protein FliG, alpha-helical THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 277 303 2.0E-65 T 13-09-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 200 225 2.0E-65 T 13-09-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 253 273 2.0E-65 T 13-09-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 231 251 2.0E-65 T 13-09-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 10 26 2.0E-65 T 13-09-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 39 65 2.0E-65 T 13-09-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THL1_RS19605 63c0f1c7460e122c913e15126181834c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 119 142 2.0E-65 T 13-09-2016 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 THL1_RS08985 c459d1456a18e8a6f78bb11298524b47 207 Pfam PF00877 NlpC/P60 family 82 191 3.9E-29 T 13-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS08985 c459d1456a18e8a6f78bb11298524b47 207 Gene3D G3DSA:3.90.1720.10 72 197 3.2E-42 T 13-09-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS08985 c459d1456a18e8a6f78bb11298524b47 207 SUPERFAMILY SSF54001 67 194 1.44E-37 T 13-09-2016 THL1_RS08985 c459d1456a18e8a6f78bb11298524b47 207 PANTHER PTHR21666 67 198 2.4E-36 T 13-09-2016 THL1_RS02885 0a8a5cde40599c7bc6ec2564f04cb7a1 182 SUPERFAMILY SSF52172 1 144 9.53E-29 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS02885 0a8a5cde40599c7bc6ec2564f04cb7a1 182 PANTHER PTHR32071 2 121 6.0E-23 T 13-09-2016 THL1_RS02885 0a8a5cde40599c7bc6ec2564f04cb7a1 182 SMART SM00448 2 114 3.7E-18 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02885 0a8a5cde40599c7bc6ec2564f04cb7a1 182 PANTHER PTHR32071:SF39 2 121 6.0E-23 T 13-09-2016 THL1_RS02885 0a8a5cde40599c7bc6ec2564f04cb7a1 182 Gene3D G3DSA:3.40.50.2300 1 134 6.7E-29 T 13-09-2016 THL1_RS02885 0a8a5cde40599c7bc6ec2564f04cb7a1 182 Pfam PF00072 Response regulator receiver domain 5 114 1.1E-18 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS04395 12d2092e71466b34cfaa21c1b86ab1dd 295 PANTHER PTHR11562 6 294 4.8E-99 T 13-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THL1_RS04395 12d2092e71466b34cfaa21c1b86ab1dd 295 Pfam PF01545 Cation efflux family 16 208 4.2E-34 T 13-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THL1_RS04395 12d2092e71466b34cfaa21c1b86ab1dd 295 Gene3D G3DSA:3.30.70.1350 209 290 3.2E-24 T 13-09-2016 IPR027470 Cation efflux protein, cytoplasmic domain THL1_RS04395 12d2092e71466b34cfaa21c1b86ab1dd 295 SUPERFAMILY SSF161111 10 210 8.63E-51 T 13-09-2016 THL1_RS04395 12d2092e71466b34cfaa21c1b86ab1dd 295 Gene3D G3DSA:1.20.1510.10 14 208 2.1E-41 T 13-09-2016 IPR027469 Cation efflux protein transmembrane domain THL1_RS04395 12d2092e71466b34cfaa21c1b86ab1dd 295 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 15 289 6.3E-63 T 13-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THL1_RS04395 12d2092e71466b34cfaa21c1b86ab1dd 295 PANTHER PTHR11562:SF55 6 294 4.8E-99 T 13-09-2016 THL1_RS04395 12d2092e71466b34cfaa21c1b86ab1dd 295 SUPERFAMILY SSF160240 214 289 4.45E-20 T 13-09-2016 THL1_RS04395 12d2092e71466b34cfaa21c1b86ab1dd 295 Pfam PF16916 Dimerisation domain of Zinc Transporter 216 288 3.9E-21 T 13-09-2016 IPR027470 Cation efflux protein, cytoplasmic domain THL1_RS02470 1ffa4a2f7027a8729cce15827956011a 270 PANTHER PTHR30143 4 270 8.0E-71 T 13-09-2016 THL1_RS02470 1ffa4a2f7027a8729cce15827956011a 270 SUPERFAMILY SSF56529 5 266 3.01E-71 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS02470 1ffa4a2f7027a8729cce15827956011a 270 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 85 264 6.0E-12 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS02470 1ffa4a2f7027a8729cce15827956011a 270 Gene3D G3DSA:3.90.850.10 6 267 5.5E-84 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS05215 871362d4b141ed7bf91c15525dc62ed2 303 Gene3D G3DSA:1.10.3720.10 90 297 2.5E-26 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS05215 871362d4b141ed7bf91c15525dc62ed2 303 PANTHER PTHR30465:SF10 11 301 5.5E-127 T 13-09-2016 THL1_RS05215 871362d4b141ed7bf91c15525dc62ed2 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 300 1.3E-28 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS05215 871362d4b141ed7bf91c15525dc62ed2 303 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 18 70 2.0E-14 T 13-09-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain THL1_RS05215 871362d4b141ed7bf91c15525dc62ed2 303 PANTHER PTHR30465 11 301 5.5E-127 T 13-09-2016 THL1_RS05215 871362d4b141ed7bf91c15525dc62ed2 303 SUPERFAMILY SSF161098 94 281 1.83E-27 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS19440 b05cb46bfc236227728f3dd9138f4260 211 SMART SM00382 30 210 4.1E-13 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS19440 b05cb46bfc236227728f3dd9138f4260 211 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS19440 b05cb46bfc236227728f3dd9138f4260 211 PANTHER PTHR24220 7 192 1.6E-93 T 13-09-2016 THL1_RS19440 b05cb46bfc236227728f3dd9138f4260 211 PANTHER PTHR24220:SF508 7 192 1.6E-93 T 13-09-2016 THL1_RS19440 b05cb46bfc236227728f3dd9138f4260 211 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 6 206 6.2E-81 T 13-09-2016 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004|GO:0030288 THL1_RS19440 b05cb46bfc236227728f3dd9138f4260 211 Gene3D G3DSA:3.40.50.300 16 192 3.1E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS19440 b05cb46bfc236227728f3dd9138f4260 211 SUPERFAMILY SSF52540 5 192 9.94E-43 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS19440 b05cb46bfc236227728f3dd9138f4260 211 Pfam PF00005 ABC transporter 22 161 3.1E-29 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS24510 d214cdbed4bbc62369d2cf489b9646b3 175 PANTHER PTHR37482 2 159 1.8E-46 T 13-09-2016 THL1_RS24510 d214cdbed4bbc62369d2cf489b9646b3 175 Pfam PF04355 SmpA / OmlA family 35 101 7.0E-25 T 13-09-2016 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 THL1_RS24510 d214cdbed4bbc62369d2cf489b9646b3 175 PANTHER PTHR37482:SF1 2 159 1.8E-46 T 13-09-2016 THL1_RS24510 d214cdbed4bbc62369d2cf489b9646b3 175 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 6 145 37.931 T 13-09-2016 IPR026592 Outer membrane protein assembly factor BamE THL1_RS13125 d7a952b0a3deb96ffd47e75fd1af4758 184 PANTHER PTHR30173:SF16 1 183 7.5E-42 T 13-09-2016 THL1_RS13125 d7a952b0a3deb96ffd47e75fd1af4758 184 SUPERFAMILY SSF88946 14 108 1.83E-23 T 13-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS13125 d7a952b0a3deb96ffd47e75fd1af4758 184 Pfam PF04542 Sigma-70 region 2 30 95 8.4E-17 T 13-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS13125 d7a952b0a3deb96ffd47e75fd1af4758 184 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 51 83 - T 13-09-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS13125 d7a952b0a3deb96ffd47e75fd1af4758 184 Gene3D G3DSA:1.10.1740.10 14 113 2.5E-23 T 13-09-2016 THL1_RS13125 d7a952b0a3deb96ffd47e75fd1af4758 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 182 9.1E-27 T 13-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS13125 d7a952b0a3deb96ffd47e75fd1af4758 184 SUPERFAMILY SSF88659 119 183 4.86E-14 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS13125 d7a952b0a3deb96ffd47e75fd1af4758 184 Gene3D G3DSA:1.10.10.10 123 183 3.7E-16 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13125 d7a952b0a3deb96ffd47e75fd1af4758 184 Pfam PF08281 Sigma-70, region 4 125 178 2.4E-12 T 13-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS13125 d7a952b0a3deb96ffd47e75fd1af4758 184 PANTHER PTHR30173 1 183 7.5E-42 T 13-09-2016 THL1_RS05090 8a1ebe71c2f262cb40d3a4ddc43a6711 540 SUPERFAMILY SSF48452 429 523 4.61E-18 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS05090 8a1ebe71c2f262cb40d3a4ddc43a6711 540 SMART SM00028 428 461 20.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS05090 8a1ebe71c2f262cb40d3a4ddc43a6711 540 SMART SM00028 462 495 4.2E-4 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS05090 8a1ebe71c2f262cb40d3a4ddc43a6711 540 Gene3D G3DSA:1.25.40.10 429 525 2.2E-17 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS06030 3d1a6b02e57d005db068b5cfb8775b80 407 SUPERFAMILY SSF50182 176 243 2.03E-11 T 13-09-2016 IPR010920 LSM domain THL1_RS06030 3d1a6b02e57d005db068b5cfb8775b80 407 PANTHER PTHR30414 1 407 2.6E-157 T 13-09-2016 THL1_RS06030 3d1a6b02e57d005db068b5cfb8775b80 407 PANTHER PTHR30414:SF0 1 407 2.6E-157 T 13-09-2016 IPR030192 Miniconductance mechanosensitive channel YbdG GO:0008381|GO:0016021|GO:0071470 THL1_RS06030 3d1a6b02e57d005db068b5cfb8775b80 407 Pfam PF00924 Mechanosensitive ion channel 134 388 2.7E-46 T 13-09-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 THL1_RS06030 3d1a6b02e57d005db068b5cfb8775b80 407 Gene3D G3DSA:2.30.30.60 193 243 9.2E-10 T 13-09-2016 THL1_RS26285 4627575707984a22bb0a41550f94c39d 552 Gene3D G3DSA:3.40.50.300 63 152 1.1E-6 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26285 4627575707984a22bb0a41550f94c39d 552 Gene3D G3DSA:3.40.50.300 153 200 3.2E-4 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26285 4627575707984a22bb0a41550f94c39d 552 Gene3D G3DSA:3.40.50.300 51 62 3.2E-4 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26285 4627575707984a22bb0a41550f94c39d 552 PANTHER PTHR35894 10 352 4.2E-12 T 13-09-2016 THL1_RS26285 4627575707984a22bb0a41550f94c39d 552 Pfam PF05036 Sporulation related domain 468 539 1.3E-9 T 13-09-2016 IPR007730 Sporulation-related domain GO:0042834 THL1_RS26285 4627575707984a22bb0a41550f94c39d 552 Pfam PF13401 AAA domain 49 170 3.2E-9 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS26285 4627575707984a22bb0a41550f94c39d 552 SUPERFAMILY SSF52540 20 246 1.42E-20 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08915 144d6322d7448829de384a8535d5857b 201 Gene3D G3DSA:2.40.160.20 63 201 4.5E-9 T 13-09-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 THL1_RS08915 144d6322d7448829de384a8535d5857b 201 Pfam PF13505 Outer membrane protein beta-barrel domain 10 201 5.3E-10 T 13-09-2016 IPR027385 Outer membrane protein beta-barrel THL1_RS08915 144d6322d7448829de384a8535d5857b 201 SUPERFAMILY SSF56925 45 201 5.23E-17 T 13-09-2016 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 THL1_RS00600 3885d3b1c3f945d43d9d83035b675c8c 214 Pfam PF00872 Transposase, Mutator family 5 211 8.4E-64 T 13-09-2016 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 THL1_RS00600 3885d3b1c3f945d43d9d83035b675c8c 214 PANTHER PTHR33217 3 211 1.2E-85 T 13-09-2016 THL1_RS22770 7133a224851ae801ca188c4a830bb947 277 SUPERFAMILY SSF52096 1 250 1.2E-62 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS22770 7133a224851ae801ca188c4a830bb947 277 PANTHER PTHR11941:SF45 2 235 3.2E-60 T 13-09-2016 THL1_RS22770 7133a224851ae801ca188c4a830bb947 277 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 247 2.5E-41 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS22770 7133a224851ae801ca188c4a830bb947 277 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 112 132 - T 13-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THL1_RS22770 7133a224851ae801ca188c4a830bb947 277 PANTHER PTHR11941 2 235 3.2E-60 T 13-09-2016 THL1_RS22770 7133a224851ae801ca188c4a830bb947 277 Gene3D G3DSA:3.90.226.10 1 234 1.6E-62 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS17750 8ad6d307dc5b8fac2f3487765cd6fc43 97 SUPERFAMILY SSF141099 1 95 8.5E-37 T 13-09-2016 IPR015073 Atu1913-like THL1_RS17750 8ad6d307dc5b8fac2f3487765cd6fc43 97 Gene3D G3DSA:4.10.1210.10 1 92 7.1E-37 T 13-09-2016 IPR015073 Atu1913-like THL1_RS17750 8ad6d307dc5b8fac2f3487765cd6fc43 97 Pfam PF08980 Domain of unknown function (DUF1883) 1 76 3.0E-31 T 13-09-2016 IPR015073 Atu1913-like THL1_RS18730 2f1cc77b632c97537a62b7b0d0b73596 151 PANTHER PTHR12935 3 142 9.0E-22 T 13-09-2016 IPR017939 Gamma-glutamylcyclotransferase GO:0003839|GO:0006750 KEGG: 00480+2.3.2.4|MetaCyc: PWY-4041 THL1_RS18730 2f1cc77b632c97537a62b7b0d0b73596 151 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 4 112 1.0E-12 T 13-09-2016 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like THL1_RS18730 2f1cc77b632c97537a62b7b0d0b73596 151 Gene3D G3DSA:3.10.490.10 2 147 3.2E-32 T 13-09-2016 IPR013024 Butirosin biosynthesis, BtrG-like THL1_RS18730 2f1cc77b632c97537a62b7b0d0b73596 151 PANTHER PTHR12935:SF0 3 142 9.0E-22 T 13-09-2016 THL1_RS18730 2f1cc77b632c97537a62b7b0d0b73596 151 SUPERFAMILY SSF110857 3 127 2.22E-18 T 13-09-2016 IPR013024 Butirosin biosynthesis, BtrG-like THL1_RS22105 fd26e3d0c9f33c7a00615e614d4ca2f2 152 PANTHER PTHR30558 1 152 8.8E-51 T 13-09-2016 THL1_RS22105 fd26e3d0c9f33c7a00615e614d4ca2f2 152 PANTHER PTHR30558:SF7 1 152 8.8E-51 T 13-09-2016 THL1_RS22105 fd26e3d0c9f33c7a00615e614d4ca2f2 152 TIGRFAM TIGR02801 tolR: protein TolR 11 150 5.0E-43 T 13-09-2016 IPR014168 Biopolymer transport, TolR GO:0015031|GO:0016021 THL1_RS22105 fd26e3d0c9f33c7a00615e614d4ca2f2 152 Pfam PF02472 Biopolymer transport protein ExbD/TolR 8 150 2.0E-26 T 13-09-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 THL1_RS10415 eff5e2c982e48a758f0bd7672b8b0316 288 PANTHER PTHR23200 10 286 3.4E-86 T 13-09-2016 THL1_RS10415 eff5e2c982e48a758f0bd7672b8b0316 288 Gene3D G3DSA:3.60.15.10 51 276 9.8E-30 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS10415 eff5e2c982e48a758f0bd7672b8b0316 288 SMART SM00849 54 272 1.3E-24 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS10415 eff5e2c982e48a758f0bd7672b8b0316 288 PANTHER PTHR23200:SF45 10 286 3.4E-86 T 13-09-2016 THL1_RS10415 eff5e2c982e48a758f0bd7672b8b0316 288 SUPERFAMILY SSF56281 53 276 4.32E-29 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS10415 eff5e2c982e48a758f0bd7672b8b0316 288 Pfam PF00753 Metallo-beta-lactamase superfamily 54 266 7.5E-22 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS01435 eeca052f08d354e48098e947fd439fd6 338 PANTHER PTHR11019:SF52 237 338 3.1E-31 T 13-09-2016 THL1_RS01435 eeca052f08d354e48098e947fd439fd6 338 Pfam PF12833 Helix-turn-helix domain 261 338 1.9E-19 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS01435 eeca052f08d354e48098e947fd439fd6 338 Gene3D G3DSA:1.10.10.60 290 338 1.2E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01435 eeca052f08d354e48098e947fd439fd6 338 SUPERFAMILY SSF46689 290 338 5.97E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01435 eeca052f08d354e48098e947fd439fd6 338 SMART SM00342 255 337 1.2E-23 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS01435 eeca052f08d354e48098e947fd439fd6 338 Gene3D G3DSA:1.10.10.60 235 277 1.5E-4 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS01435 eeca052f08d354e48098e947fd439fd6 338 PANTHER PTHR11019 237 338 3.1E-31 T 13-09-2016 THL1_RS01435 eeca052f08d354e48098e947fd439fd6 338 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 29 212 1.2E-47 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS17490 99bb80e02cae73e69edeef5753ad8fd9 240 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS17490 99bb80e02cae73e69edeef5753ad8fd9 240 SMART SM00382 36 219 2.7E-10 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS17490 99bb80e02cae73e69edeef5753ad8fd9 240 Pfam PF00005 ABC transporter 27 168 3.3E-24 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS17490 99bb80e02cae73e69edeef5753ad8fd9 240 Gene3D G3DSA:3.40.50.300 9 229 1.8E-50 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17490 99bb80e02cae73e69edeef5753ad8fd9 240 PANTHER PTHR24220 13 227 2.4E-79 T 13-09-2016 THL1_RS17490 99bb80e02cae73e69edeef5753ad8fd9 240 SUPERFAMILY SSF52540 12 233 8.58E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17490 99bb80e02cae73e69edeef5753ad8fd9 240 PANTHER PTHR24220:SF568 13 227 2.4E-79 T 13-09-2016 THL1_RS13335 453986d18ea0791e91d020620f375914 286 Pfam PF12833 Helix-turn-helix domain 193 271 4.0E-18 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS13335 453986d18ea0791e91d020620f375914 286 PANTHER PTHR11019 33 277 1.2E-43 T 13-09-2016 THL1_RS13335 453986d18ea0791e91d020620f375914 286 SMART SM00342 187 269 3.8E-25 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS13335 453986d18ea0791e91d020620f375914 286 SUPERFAMILY SSF46689 223 271 2.69E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13335 453986d18ea0791e91d020620f375914 286 SUPERFAMILY SSF46689 170 220 5.82E-7 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13335 453986d18ea0791e91d020620f375914 286 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 224 265 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS13335 453986d18ea0791e91d020620f375914 286 PANTHER PTHR11019:SF77 33 277 1.2E-43 T 13-09-2016 THL1_RS13335 453986d18ea0791e91d020620f375914 286 Gene3D G3DSA:1.10.10.60 169 225 2.4E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13335 453986d18ea0791e91d020620f375914 286 Gene3D G3DSA:1.10.10.60 226 273 5.5E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13335 453986d18ea0791e91d020620f375914 286 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 172 216 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS13335 453986d18ea0791e91d020620f375914 286 Pfam PF12852 Cupin 2 155 6.6E-18 T 13-09-2016 IPR032783 AraC-type transcription regulator, ligand-binding domain THL1_RS15120 105cf45d7a5e23f1a56b1739c29dbc01 346 Pfam PF05155 Phage X family 253 336 3.9E-29 T 13-09-2016 IPR022688 Replication-associated protein G2P, C-terminal GO:0006260 THL1_RS15120 105cf45d7a5e23f1a56b1739c29dbc01 346 Pfam PF05144 Phage replication protein CRI 1 222 2.2E-52 T 13-09-2016 IPR022686 Replication-associated protein G2P, N-terminal GO:0006260 THL1_RS15120 105cf45d7a5e23f1a56b1739c29dbc01 346 TIGRFAM TIGR01629 rep_II_X: phage/plasmid replication protein, gene II/X family 2 336 2.1E-60 T 13-09-2016 IPR006516 Replication-associated protein G2P GO:0006260 THL1_RS15250 105cf45d7a5e23f1a56b1739c29dbc01 346 Pfam PF05155 Phage X family 253 336 3.9E-29 T 13-09-2016 IPR022688 Replication-associated protein G2P, C-terminal GO:0006260 THL1_RS15250 105cf45d7a5e23f1a56b1739c29dbc01 346 Pfam PF05144 Phage replication protein CRI 1 222 2.2E-52 T 13-09-2016 IPR022686 Replication-associated protein G2P, N-terminal GO:0006260 THL1_RS15250 105cf45d7a5e23f1a56b1739c29dbc01 346 TIGRFAM TIGR01629 rep_II_X: phage/plasmid replication protein, gene II/X family 2 336 2.1E-60 T 13-09-2016 IPR006516 Replication-associated protein G2P GO:0006260 THL1_RS15200 105cf45d7a5e23f1a56b1739c29dbc01 346 Pfam PF05155 Phage X family 253 336 3.9E-29 T 13-09-2016 IPR022688 Replication-associated protein G2P, C-terminal GO:0006260 THL1_RS15200 105cf45d7a5e23f1a56b1739c29dbc01 346 Pfam PF05144 Phage replication protein CRI 1 222 2.2E-52 T 13-09-2016 IPR022686 Replication-associated protein G2P, N-terminal GO:0006260 THL1_RS15200 105cf45d7a5e23f1a56b1739c29dbc01 346 TIGRFAM TIGR01629 rep_II_X: phage/plasmid replication protein, gene II/X family 2 336 2.1E-60 T 13-09-2016 IPR006516 Replication-associated protein G2P GO:0006260 THL1_RS07350 d49339a878148f0d48468ea89f999e8b 377 Pfam PF03576 Peptidase family S58 21 350 6.3E-107 T 13-09-2016 IPR005321 Peptidase S58, DmpA THL1_RS07350 d49339a878148f0d48468ea89f999e8b 377 SUPERFAMILY SSF56266 2 367 7.85E-110 T 13-09-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 THL1_RS07350 d49339a878148f0d48468ea89f999e8b 377 PANTHER PTHR36512 3 367 1.7E-150 T 13-09-2016 THL1_RS07350 d49339a878148f0d48468ea89f999e8b 377 PANTHER PTHR36512:SF1 3 367 1.7E-150 T 13-09-2016 THL1_RS07350 d49339a878148f0d48468ea89f999e8b 377 Gene3D G3DSA:3.60.70.12 3 366 1.3E-125 T 13-09-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 THL1_RS14465 c6fcdf40a2f247dff89383cb25540b25 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS14465 c6fcdf40a2f247dff89383cb25540b25 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.2E-9 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14465 c6fcdf40a2f247dff89383cb25540b25 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 1.2E-9 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14465 c6fcdf40a2f247dff89383cb25540b25 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 1.2E-9 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14465 c6fcdf40a2f247dff89383cb25540b25 252 PANTHER PTHR24322 8 131 3.9E-47 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14465 c6fcdf40a2f247dff89383cb25540b25 252 PANTHER PTHR24322 147 183 3.9E-47 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14465 c6fcdf40a2f247dff89383cb25540b25 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 8.0E-34 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14465 c6fcdf40a2f247dff89383cb25540b25 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 8.0E-34 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14465 c6fcdf40a2f247dff89383cb25540b25 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 8.0E-34 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14465 c6fcdf40a2f247dff89383cb25540b25 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 8.0E-34 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14465 c6fcdf40a2f247dff89383cb25540b25 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 8.0E-34 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14465 c6fcdf40a2f247dff89383cb25540b25 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 8.0E-34 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14465 c6fcdf40a2f247dff89383cb25540b25 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 249 6.2E-54 T 13-09-2016 THL1_RS14465 c6fcdf40a2f247dff89383cb25540b25 252 SUPERFAMILY SSF51735 5 250 4.81E-69 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS14465 c6fcdf40a2f247dff89383cb25540b25 252 Gene3D G3DSA:3.40.50.720 3 250 2.4E-74 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS14465 c6fcdf40a2f247dff89383cb25540b25 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 186 0.0015 T 13-09-2016 THL1_RS10320 4b3a8b498330003f1b54cc5c23f7eab2 292 PANTHER PTHR33608 4 292 9.9E-115 T 13-09-2016 THL1_RS10320 4b3a8b498330003f1b54cc5c23f7eab2 292 Pfam PF01882 Protein of unknown function DUF58 32 116 1.2E-19 T 13-09-2016 IPR002881 Domain of unknown function DUF58 THL1_RS10320 4b3a8b498330003f1b54cc5c23f7eab2 292 PANTHER PTHR33608:SF6 4 292 9.9E-115 T 13-09-2016 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 Gene3D G3DSA:3.40.1110.10 319 534 6.3E-48 T 13-09-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 Gene3D G3DSA:1.20.1110.10 596 883 3.3E-105 T 13-09-2016 IPR023298 P-type ATPase, transmembrane domain THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 Gene3D G3DSA:1.20.1110.10 61 113 3.3E-105 T 13-09-2016 IPR023298 P-type ATPase, transmembrane domain THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 Pfam PF00122 E1-E2 ATPase 86 320 8.2E-64 T 13-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 331 337 - T 13-09-2016 IPR018303 P-type ATPase, phosphorylation site THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 Gene3D G3DSA:2.70.150.10 26 60 3.1E-38 T 13-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 Gene3D G3DSA:2.70.150.10 114 227 3.1E-38 T 13-09-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 SUPERFAMILY SSF81653 122 227 8.89E-29 T 13-09-2016 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 Pfam PF00689 Cation transporting ATPase, C-terminus 712 882 3.5E-47 T 13-09-2016 IPR006068 Cation-transporting P-type ATPase, C-terminal THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 549 559 7.4E-41 T 13-09-2016 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 651 663 7.4E-41 T 13-09-2016 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 527 538 7.4E-41 T 13-09-2016 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 627 646 7.4E-41 T 13-09-2016 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 166 180 7.4E-41 T 13-09-2016 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 329 343 7.4E-41 T 13-09-2016 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 Pfam PF00702 haloacid dehalogenase-like hydrolase 326 641 1.4E-22 T 13-09-2016 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 SUPERFAMILY SSF81665 8 119 2.88E-119 T 13-09-2016 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 SUPERFAMILY SSF81665 677 884 2.88E-119 T 13-09-2016 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 SUPERFAMILY SSF81665 229 323 2.88E-119 T 13-09-2016 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 SUPERFAMILY SSF56784 327 347 6.59E-58 T 13-09-2016 IPR023214 HAD-like domain THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 SUPERFAMILY SSF56784 482 732 6.59E-58 T 13-09-2016 IPR023214 HAD-like domain THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 PANTHER PTHR24093 5 763 4.3E-295 T 13-09-2016 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 PANTHER PTHR24093 780 895 4.3E-295 T 13-09-2016 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 Pfam PF00690 Cation transporter/ATPase, N-terminus 9 75 1.4E-16 T 13-09-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 597 716 1.9E-31 T 13-09-2016 IPR001757 P-type ATPase GO:0016021 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 87 350 5.2E-42 T 13-09-2016 IPR001757 P-type ATPase GO:0016021 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 599 615 8.8E-16 T 13-09-2016 IPR001757 P-type ATPase GO:0016021 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 659 684 8.8E-16 T 13-09-2016 IPR001757 P-type ATPase GO:0016021 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 627 643 8.8E-16 T 13-09-2016 IPR001757 P-type ATPase GO:0016021 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 485 503 8.8E-16 T 13-09-2016 IPR001757 P-type ATPase GO:0016021 THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 SMART SM00831 8 81 8.9E-34 T 13-09-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal THL1_RS16025 686e9e0b34dc7c0270403fe3b5c5add4 895 SUPERFAMILY SSF81660 336 531 8.5E-43 T 13-09-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 THL1_RS10670 573edbe7b55e3cbff8b1d2abf9d01602 173 Pfam PF10972 Peptidoglycan-binding protein, CsiV 59 172 3.6E-17 T 13-09-2016 IPR021241 Peptidoglycan-binding protein, CsiV THL1_RS20015 4126c817fe5e6a618668d663b78c66b1 192 SUPERFAMILY SSF48613 5 186 2.13E-53 T 13-09-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 THL1_RS20015 4126c817fe5e6a618668d663b78c66b1 192 Pfam PF01126 Heme oxygenase 6 184 4.3E-19 T 13-09-2016 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|Reactome: REACT_9431 THL1_RS20015 4126c817fe5e6a618668d663b78c66b1 192 Gene3D G3DSA:1.20.910.10 3 185 5.2E-71 T 13-09-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 THL1_RS22685 c241df3d42b2b07f003c07759bba822d 383 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 260 280 - T 13-09-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 THL1_RS22685 c241df3d42b2b07f003c07759bba822d 383 PANTHER PTHR11496 1 383 1.9E-205 T 13-09-2016 THL1_RS22685 c241df3d42b2b07f003c07759bba822d 383 Gene3D G3DSA:1.20.1090.10 181 382 2.7E-51 T 13-09-2016 THL1_RS22685 c241df3d42b2b07f003c07759bba822d 383 PANTHER PTHR11496:SF65 1 383 1.9E-205 T 13-09-2016 THL1_RS22685 c241df3d42b2b07f003c07759bba822d 383 Gene3D G3DSA:3.40.50.1970 1 180 4.4E-54 T 13-09-2016 THL1_RS22685 c241df3d42b2b07f003c07759bba822d 383 SUPERFAMILY SSF56796 2 364 5.63E-108 T 13-09-2016 THL1_RS22685 c241df3d42b2b07f003c07759bba822d 383 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 356 6.3E-90 T 13-09-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 THL1_RS19830 81948ca497bb9b5e3f6b57c1dfd5cb8b 141 SUPERFAMILY SSF82784 1 140 1.96E-44 T 13-09-2016 IPR003718 OsmC/Ohr family THL1_RS19830 81948ca497bb9b5e3f6b57c1dfd5cb8b 141 PANTHER PTHR33797 1 140 6.1E-68 T 13-09-2016 THL1_RS19830 81948ca497bb9b5e3f6b57c1dfd5cb8b 141 Pfam PF02566 OsmC-like protein 43 138 2.7E-17 T 13-09-2016 IPR003718 OsmC/Ohr family THL1_RS19830 81948ca497bb9b5e3f6b57c1dfd5cb8b 141 Gene3D G3DSA:2.20.25.10 2 47 7.9E-23 T 13-09-2016 THL1_RS19830 81948ca497bb9b5e3f6b57c1dfd5cb8b 141 PANTHER PTHR33797:SF2 1 140 6.1E-68 T 13-09-2016 THL1_RS19830 81948ca497bb9b5e3f6b57c1dfd5cb8b 141 Gene3D G3DSA:3.30.300.20 48 140 1.2E-34 T 13-09-2016 IPR015946 K homology domain-like, alpha/beta THL1_RS19830 81948ca497bb9b5e3f6b57c1dfd5cb8b 141 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 7 139 1.7E-54 T 13-09-2016 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 THL1_RS00815 e87bd0769c453d3a983fccc0eeb7a4b1 396 Pfam PF07690 Major Facilitator Superfamily 14 344 2.6E-46 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS00815 e87bd0769c453d3a983fccc0eeb7a4b1 396 PANTHER PTHR23501 9 383 1.8E-111 T 13-09-2016 THL1_RS00815 e87bd0769c453d3a983fccc0eeb7a4b1 396 SUPERFAMILY SSF103473 9 383 9.16E-67 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS00815 e87bd0769c453d3a983fccc0eeb7a4b1 396 PANTHER PTHR23501:SF4 9 383 1.8E-111 T 13-09-2016 THL1_RS00815 e87bd0769c453d3a983fccc0eeb7a4b1 396 Gene3D G3DSA:1.20.1250.20 11 192 1.1E-35 T 13-09-2016 THL1_RS00815 e87bd0769c453d3a983fccc0eeb7a4b1 396 Gene3D G3DSA:1.20.1250.20 204 383 1.1E-16 T 13-09-2016 THL1_RS11135 566d0dd3b3255e68d91a1c7b0c786520 329 PANTHER PTHR11732 1 326 1.1E-156 T 13-09-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta THL1_RS11135 566d0dd3b3255e68d91a1c7b0c786520 329 SUPERFAMILY SSF51430 1 313 2.1E-94 T 13-09-2016 IPR023210 NADP-dependent oxidoreductase domain THL1_RS11135 566d0dd3b3255e68d91a1c7b0c786520 329 Gene3D G3DSA:3.20.20.100 1 321 2.5E-104 T 13-09-2016 IPR023210 NADP-dependent oxidoreductase domain THL1_RS11135 566d0dd3b3255e68d91a1c7b0c786520 329 Pfam PF00248 Aldo/keto reductase family 13 306 9.9E-75 T 13-09-2016 IPR023210 NADP-dependent oxidoreductase domain THL1_RS11135 566d0dd3b3255e68d91a1c7b0c786520 329 PANTHER PTHR11732:SF215 1 326 1.1E-156 T 13-09-2016 THL1_RS28300 dbb2d828902b997051f7419b2953e3cf 455 Gene3D G3DSA:3.30.590.10 120 439 1.3E-94 T 13-09-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 THL1_RS28300 dbb2d828902b997051f7419b2953e3cf 455 PANTHER PTHR20852 7 452 1.7E-133 T 13-09-2016 THL1_RS28300 dbb2d828902b997051f7419b2953e3cf 455 Pfam PF00120 Glutamine synthetase, catalytic domain 118 451 2.0E-105 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS28300 dbb2d828902b997051f7419b2953e3cf 455 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 254 269 - T 13-09-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS28300 dbb2d828902b997051f7419b2953e3cf 455 PANTHER PTHR20852:SF7 7 452 1.7E-133 T 13-09-2016 THL1_RS28300 dbb2d828902b997051f7419b2953e3cf 455 SUPERFAMILY SSF55931 117 452 9.81E-105 T 13-09-2016 THL1_RS28300 dbb2d828902b997051f7419b2953e3cf 455 Gene3D G3DSA:3.10.20.70 7 114 2.6E-7 T 13-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS28300 dbb2d828902b997051f7419b2953e3cf 455 SUPERFAMILY SSF54368 7 114 2.75E-10 T 13-09-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS28300 dbb2d828902b997051f7419b2953e3cf 455 SMART SM01230 117 373 2.1E-101 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS12440 26e88b11e9bcb3b805ee69db98f052c8 327 Pfam PF02885 Glycosyl transferase family, helical bundle domain 22 76 8.5E-17 T 13-09-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain THL1_RS12440 26e88b11e9bcb3b805ee69db98f052c8 327 Gene3D G3DSA:1.20.970.10 18 76 2.3E-18 T 13-09-2016 THL1_RS12440 26e88b11e9bcb3b805ee69db98f052c8 327 Gene3D G3DSA:3.40.1030.10 87 321 2.3E-36 T 13-09-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 THL1_RS12440 26e88b11e9bcb3b805ee69db98f052c8 327 SUPERFAMILY SSF52418 82 324 4.55E-56 T 13-09-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 THL1_RS12440 26e88b11e9bcb3b805ee69db98f052c8 327 PANTHER PTHR10515 1 272 7.9E-50 T 13-09-2016 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 THL1_RS12440 26e88b11e9bcb3b805ee69db98f052c8 327 Pfam PF00591 Glycosyl transferase family, a/b domain 105 251 2.5E-4 T 13-09-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 THL1_RS12440 26e88b11e9bcb3b805ee69db98f052c8 327 SUPERFAMILY SSF47648 18 77 2.62E-16 T 13-09-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain THL1_RS20125 a225224eb9ee949a99e58557ce744808 137 Pfam PF11776 Nickel/cobalt transporter regulator 102 129 2.2E-7 T 13-09-2016 IPR024572 Nickel/cobalt homeostasis protein RcnB THL1_RS20790 ea3316a0d28b0348e8eb2024f9b27379 832 Gene3D G3DSA:1.20.1640.10 209 402 3.3E-19 T 13-09-2016 THL1_RS20790 ea3316a0d28b0348e8eb2024f9b27379 832 Gene3D G3DSA:1.20.1640.10 643 796 3.4E-21 T 13-09-2016 THL1_RS20790 ea3316a0d28b0348e8eb2024f9b27379 832 PANTHER PTHR33406:SF2 145 832 3.0E-89 T 13-09-2016 THL1_RS20790 ea3316a0d28b0348e8eb2024f9b27379 832 PANTHER PTHR33406:SF2 14 121 3.0E-89 T 13-09-2016 THL1_RS20790 ea3316a0d28b0348e8eb2024f9b27379 832 SUPERFAMILY SSF82866 644 795 6.54E-28 T 13-09-2016 THL1_RS20790 ea3316a0d28b0348e8eb2024f9b27379 832 PANTHER PTHR33406 145 832 3.0E-89 T 13-09-2016 THL1_RS20790 ea3316a0d28b0348e8eb2024f9b27379 832 PANTHER PTHR33406 14 121 3.0E-89 T 13-09-2016 THL1_RS20790 ea3316a0d28b0348e8eb2024f9b27379 832 Pfam PF03176 MMPL family 182 436 1.9E-8 T 13-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 THL1_RS20790 ea3316a0d28b0348e8eb2024f9b27379 832 Pfam PF03176 MMPL family 623 792 5.5E-12 T 13-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 THL1_RS20790 ea3316a0d28b0348e8eb2024f9b27379 832 SUPERFAMILY SSF82866 186 400 9.94E-23 T 13-09-2016 THL1_RS15590 75d8b24a323d5042ea9c76fb9be0bf0d 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 13-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THL1_RS15590 75d8b24a323d5042ea9c76fb9be0bf0d 257 SUPERFAMILY SSF52096 1 255 5.13E-88 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS15590 75d8b24a323d5042ea9c76fb9be0bf0d 257 PANTHER PTHR11941:SF54 1 254 1.5E-112 T 13-09-2016 THL1_RS15590 75d8b24a323d5042ea9c76fb9be0bf0d 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 255 1.7E-78 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS15590 75d8b24a323d5042ea9c76fb9be0bf0d 257 PANTHER PTHR11941 1 254 1.5E-112 T 13-09-2016 THL1_RS15590 75d8b24a323d5042ea9c76fb9be0bf0d 257 Gene3D G3DSA:3.90.226.10 1 254 1.2E-96 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS23775 ee7a9705392868b0e06055d766bf0f79 332 Pfam PF05175 Methyltransferase small domain 162 328 6.5E-53 T 13-09-2016 IPR007848 Methyltransferase small domain GO:0008168 THL1_RS23775 ee7a9705392868b0e06055d766bf0f79 332 Hamap MF_01862 Ribosomal RNA small subunit methyltransferase C [rsmC]. 1 331 40.997 T 13-09-2016 IPR023543 rRNA small subunit methyltransferase C GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS23775 ee7a9705392868b0e06055d766bf0f79 332 SUPERFAMILY SSF53335 93 303 3.44E-23 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS23775 ee7a9705392868b0e06055d766bf0f79 332 PANTHER PTHR18895 72 329 8.3E-96 T 13-09-2016 THL1_RS23775 ee7a9705392868b0e06055d766bf0f79 332 PANTHER PTHR18895:SF70 72 329 8.3E-96 T 13-09-2016 THL1_RS23775 ee7a9705392868b0e06055d766bf0f79 332 Pfam PF08468 Methyltransferase small domain N-terminal 5 153 3.7E-40 T 13-09-2016 IPR013675 Methyltransferase small, N-terminal GO:0006364|GO:0008990 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS23775 ee7a9705392868b0e06055d766bf0f79 332 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 260 266 - T 13-09-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THL1_RS23775 ee7a9705392868b0e06055d766bf0f79 332 Gene3D G3DSA:3.40.50.150 180 295 1.2E-16 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS17090 b735ccf9bf1eb1de627a590f43210a76 98 Gene3D G3DSA:3.30.70.900 3 94 1.3E-20 T 13-09-2016 THL1_RS17090 b735ccf9bf1eb1de627a590f43210a76 98 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 93 1.5E-13 T 13-09-2016 IPR009799 EthD domain THL1_RS17090 b735ccf9bf1eb1de627a590f43210a76 98 SUPERFAMILY SSF54909 1 95 1.02E-13 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS17090 b735ccf9bf1eb1de627a590f43210a76 98 PANTHER PTHR40260 1 97 1.7E-17 T 13-09-2016 THL1_RS04405 c0a9b6247a5609f735c196660587e74b 840 Gene3D G3DSA:3.40.50.300 4 164 1.6E-46 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04405 c0a9b6247a5609f735c196660587e74b 840 Pfam PF00271 Helicase conserved C-terminal domain 212 333 1.1E-12 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS04405 c0a9b6247a5609f735c196660587e74b 840 SUPERFAMILY SSF52540 15 162 7.27E-26 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04405 c0a9b6247a5609f735c196660587e74b 840 SMART SM00490 234 334 2.5E-19 T 13-09-2016 IPR001650 Helicase, C-terminal THL1_RS04405 c0a9b6247a5609f735c196660587e74b 840 Pfam PF08482 ATP-dependent helicase C-terminal 696 827 2.1E-52 T 13-09-2016 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal THL1_RS04405 c0a9b6247a5609f735c196660587e74b 840 SMART SM00487 5 189 5.6E-17 T 13-09-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain THL1_RS04405 c0a9b6247a5609f735c196660587e74b 840 SUPERFAMILY SSF52540 181 448 1.97E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04405 c0a9b6247a5609f735c196660587e74b 840 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 4 839 0.0 T 13-09-2016 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type THL1_RS04405 c0a9b6247a5609f735c196660587e74b 840 SMART SM00847 394 498 6.9E-15 T 13-09-2016 IPR007502 Helicase-associated domain GO:0004386 THL1_RS04405 c0a9b6247a5609f735c196660587e74b 840 Gene3D G3DSA:3.40.50.300 206 350 2.0E-17 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04405 c0a9b6247a5609f735c196660587e74b 840 PANTHER PTHR18934 653 667 8.4E-157 T 13-09-2016 THL1_RS04405 c0a9b6247a5609f735c196660587e74b 840 PANTHER PTHR18934 4 457 8.4E-157 T 13-09-2016 THL1_RS04405 c0a9b6247a5609f735c196660587e74b 840 PIRSF PIRSF005496 1 840 0.0 T 13-09-2016 IPR010225 RNA helicase, ATP-dependent DEAH box, HrpB-type THL1_RS04405 c0a9b6247a5609f735c196660587e74b 840 Pfam PF04408 Helicase associated domain (HA2) 397 471 2.9E-13 T 13-09-2016 IPR007502 Helicase-associated domain GO:0004386 THL1_RS04405 c0a9b6247a5609f735c196660587e74b 840 Pfam PF00270 DEAD/DEAH box helicase 19 167 5.4E-6 T 13-09-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THL1_RS04170 1820a7810a1e421e9ca81950b2982809 151 SUPERFAMILY SSF54637 7 146 4.89E-39 T 13-09-2016 IPR029069 HotDog domain THL1_RS04170 1820a7810a1e421e9ca81950b2982809 151 Gene3D G3DSA:3.10.129.10 13 147 6.5E-36 T 13-09-2016 IPR029069 HotDog domain THL1_RS04170 1820a7810a1e421e9ca81950b2982809 151 PANTHER PTHR13078 12 145 3.8E-39 T 13-09-2016 THL1_RS04170 1820a7810a1e421e9ca81950b2982809 151 Pfam PF01575 MaoC like domain 11 118 7.2E-27 T 13-09-2016 IPR002539 MaoC-like domain THL1_RS27390 1982c95c91bd77b5682ed485cebf54fc 210 PANTHER PTHR30086 1 210 2.2E-97 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS27390 1982c95c91bd77b5682ed485cebf54fc 210 PANTHER PTHR30086:SF14 1 210 2.2E-97 T 13-09-2016 THL1_RS27390 1982c95c91bd77b5682ed485cebf54fc 210 PIRSF PIRSF006324 1 207 1.9E-53 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS27390 1982c95c91bd77b5682ed485cebf54fc 210 Pfam PF01810 LysE type translocator 16 204 1.7E-34 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS27080 2e93ff8ac70ed0c1ed044945e67ae54d 596 SUPERFAMILY SSF56645 39 277 2.49E-53 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS27080 2e93ff8ac70ed0c1ed044945e67ae54d 596 Gene3D G3DSA:1.10.540.10 39 156 4.3E-16 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS27080 2e93ff8ac70ed0c1ed044945e67ae54d 596 Gene3D G3DSA:1.20.140.10 266 458 6.7E-53 T 13-09-2016 THL1_RS27080 2e93ff8ac70ed0c1ed044945e67ae54d 596 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 160 268 6.8E-16 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS27080 2e93ff8ac70ed0c1ed044945e67ae54d 596 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 473 590 5.3E-30 T 13-09-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain THL1_RS27080 2e93ff8ac70ed0c1ed044945e67ae54d 596 Gene3D G3DSA:2.40.110.10 158 265 4.4E-24 T 13-09-2016 THL1_RS27080 2e93ff8ac70ed0c1ed044945e67ae54d 596 SUPERFAMILY SSF47203 284 456 4.51E-46 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS27080 2e93ff8ac70ed0c1ed044945e67ae54d 596 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 42 154 6.7E-12 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS27080 2e93ff8ac70ed0c1ed044945e67ae54d 596 PANTHER PTHR10909:SF296 3 473 2.0E-247 T 13-09-2016 THL1_RS27080 2e93ff8ac70ed0c1ed044945e67ae54d 596 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 26 8.0E-10 T 13-09-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria THL1_RS27080 2e93ff8ac70ed0c1ed044945e67ae54d 596 PANTHER PTHR10909 3 473 2.0E-247 T 13-09-2016 THL1_RS27080 2e93ff8ac70ed0c1ed044945e67ae54d 596 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 279 451 4.5E-23 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS08095 0097da74bb85f677397fbc11a0f24f17 184 PANTHER PTHR30335 2 184 9.0E-14 T 13-09-2016 THL1_RS08095 0097da74bb85f677397fbc11a0f24f17 184 Pfam PF02508 Rnf-Nqr subunit, membrane protein 7 181 6.0E-15 T 13-09-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 THL1_RS08095 0097da74bb85f677397fbc11a0f24f17 184 PANTHER PTHR30335:SF0 2 184 9.0E-14 T 13-09-2016 THL1_RS09995 4bba097b1229eccb24f38ab0caf8a70b 324 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 92 110 - T 13-09-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 THL1_RS09995 4bba097b1229eccb24f38ab0caf8a70b 324 Hamap MF_02043 tRNA-dihydrouridine(16) synthase [dusC]. 8 314 52.976 T 13-09-2016 IPR032886 tRNA-dihydrouridine(16) synthase GO:0002943|GO:0017150 THL1_RS09995 4bba097b1229eccb24f38ab0caf8a70b 324 PANTHER PTHR11082:SF26 1 311 1.5E-158 T 13-09-2016 THL1_RS09995 4bba097b1229eccb24f38ab0caf8a70b 324 PANTHER PTHR11082 1 311 1.5E-158 T 13-09-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 THL1_RS09995 4bba097b1229eccb24f38ab0caf8a70b 324 Gene3D G3DSA:3.20.20.70 2 244 8.0E-64 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS09995 4bba097b1229eccb24f38ab0caf8a70b 324 PIRSF PIRSF006621 1 324 5.8E-77 T 13-09-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 THL1_RS09995 4bba097b1229eccb24f38ab0caf8a70b 324 Pfam PF01207 Dihydrouridine synthase (Dus) 5 253 7.5E-65 T 13-09-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 THL1_RS09995 4bba097b1229eccb24f38ab0caf8a70b 324 SUPERFAMILY SSF51395 2 306 1.17E-69 T 13-09-2016 THL1_RS19095 39e5c57d5f879fc903ac2badf449fd56 142 Pfam PF12680 SnoaL-like domain 15 111 6.0E-11 T 13-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain THL1_RS19095 39e5c57d5f879fc903ac2badf449fd56 142 SUPERFAMILY SSF54427 10 118 3.51E-22 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS19095 39e5c57d5f879fc903ac2badf449fd56 142 Gene3D G3DSA:3.10.450.50 9 119 1.2E-19 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS18120 1f1dd2e42fb791dce5ef633d9a8f8034 245 PANTHER PTHR21091:SF16 1 232 2.9E-68 T 13-09-2016 THL1_RS18120 1f1dd2e42fb791dce5ef633d9a8f8034 245 Gene3D G3DSA:3.30.950.10 123 241 4.3E-39 T 13-09-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 THL1_RS18120 1f1dd2e42fb791dce5ef633d9a8f8034 245 SUPERFAMILY SSF53790 1 235 6.94E-70 T 13-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 THL1_RS18120 1f1dd2e42fb791dce5ef633d9a8f8034 245 PANTHER PTHR21091 1 232 2.9E-68 T 13-09-2016 THL1_RS18120 1f1dd2e42fb791dce5ef633d9a8f8034 245 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 234 3.5E-92 T 13-09-2016 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 THL1_RS18120 1f1dd2e42fb791dce5ef633d9a8f8034 245 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 212 3.7E-43 T 13-09-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 THL1_RS18120 1f1dd2e42fb791dce5ef633d9a8f8034 245 Gene3D G3DSA:3.40.1010.10 1 117 4.9E-41 T 13-09-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 THL1_RS18120 1f1dd2e42fb791dce5ef633d9a8f8034 245 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 13-09-2016 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377|UniPathway: UPA00148|UniPathway: UPA00148|UniPathway: UPA00262|UniPathway: UPA00262|UniPathway: UPA00262 THL1_RS01510 1628da177b48e9af8af496cc9f0f4613 297 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 211 288 2.3E-15 T 13-09-2016 IPR006260 TonB, C-terminal GO:0006810 THL1_RS01510 1628da177b48e9af8af496cc9f0f4613 297 SUPERFAMILY SSF74653 185 292 3.53E-19 T 13-09-2016 THL1_RS01510 1628da177b48e9af8af496cc9f0f4613 297 Gene3D G3DSA:3.30.1150.10 187 292 2.2E-21 T 13-09-2016 THL1_RS01510 1628da177b48e9af8af496cc9f0f4613 297 PANTHER PTHR33446 1 278 9.3E-60 T 13-09-2016 THL1_RS01510 1628da177b48e9af8af496cc9f0f4613 297 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 213 289 2.1E-15 T 13-09-2016 IPR006260 TonB, C-terminal GO:0006810 THL1_RS01510 1628da177b48e9af8af496cc9f0f4613 297 PANTHER PTHR33446:SF2 1 278 9.3E-60 T 13-09-2016 THL1_RS23290 219615f3fbc018130b4cbbe45cf12ef9 494 PANTHER PTHR11895 16 486 1.7E-202 T 13-09-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS23290 219615f3fbc018130b4cbbe45cf12ef9 494 PANTHER PTHR11895:SF76 16 486 1.7E-202 T 13-09-2016 THL1_RS23290 219615f3fbc018130b4cbbe45cf12ef9 494 Gene3D G3DSA:3.90.1300.10 16 487 1.6E-118 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS23290 219615f3fbc018130b4cbbe45cf12ef9 494 SUPERFAMILY SSF75304 17 487 4.97E-122 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS23290 219615f3fbc018130b4cbbe45cf12ef9 494 Pfam PF01425 Amidase 39 469 9.2E-87 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS02655 6a81270fb105a34f9b87016787994533 369 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS02655 6a81270fb105a34f9b87016787994533 369 Pfam PF00005 ABC transporter 28 169 2.0E-34 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS02655 6a81270fb105a34f9b87016787994533 369 Gene3D G3DSA:3.40.50.300 5 246 1.9E-80 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS02655 6a81270fb105a34f9b87016787994533 369 SUPERFAMILY SSF50331 244 363 2.32E-19 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS02655 6a81270fb105a34f9b87016787994533 369 PANTHER PTHR24220:SF402 12 361 1.6E-218 T 13-09-2016 THL1_RS02655 6a81270fb105a34f9b87016787994533 369 PANTHER PTHR24220 12 361 1.6E-218 T 13-09-2016 THL1_RS02655 6a81270fb105a34f9b87016787994533 369 SMART SM00382 36 219 2.4E-16 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS02655 6a81270fb105a34f9b87016787994533 369 Pfam PF08402 TOBE domain 286 363 3.8E-17 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS02655 6a81270fb105a34f9b87016787994533 369 SUPERFAMILY SSF52540 10 248 2.05E-87 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS02655 6a81270fb105a34f9b87016787994533 369 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 42 361 1.7E-114 T 13-09-2016 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 THL1_RS03360 34a6b9a3469423d1fecf9d453267b884 320 PANTHER PTHR32332 2 320 1.6E-189 T 13-09-2016 THL1_RS03360 34a6b9a3469423d1fecf9d453267b884 320 SUPERFAMILY SSF51412 6 301 1.52E-56 T 13-09-2016 THL1_RS03360 34a6b9a3469423d1fecf9d453267b884 320 PANTHER PTHR32332:SF21 2 320 1.6E-189 T 13-09-2016 THL1_RS03360 34a6b9a3469423d1fecf9d453267b884 320 Pfam PF03060 Nitronate monooxygenase 88 300 3.3E-24 T 13-09-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 THL1_RS03360 34a6b9a3469423d1fecf9d453267b884 320 Gene3D G3DSA:3.20.20.70 7 297 3.5E-49 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS23005 a383401594ed547bd3a90a0f2ac1fa9c 568 SUPERFAMILY SSF52091 441 551 3.53E-11 T 13-09-2016 IPR002645 STAS domain THL1_RS23005 a383401594ed547bd3a90a0f2ac1fa9c 568 Pfam PF01740 STAS domain 439 543 1.3E-13 T 13-09-2016 IPR002645 STAS domain THL1_RS23005 a383401594ed547bd3a90a0f2ac1fa9c 568 PANTHER PTHR11814 15 545 1.8E-153 T 13-09-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 THL1_RS23005 a383401594ed547bd3a90a0f2ac1fa9c 568 Gene3D G3DSA:3.30.750.24 443 550 6.1E-11 T 13-09-2016 IPR002645 STAS domain THL1_RS23005 a383401594ed547bd3a90a0f2ac1fa9c 568 TIGRFAM TIGR00815 sulP: sulfate permease 14 535 1.7E-118 T 13-09-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 THL1_RS23005 a383401594ed547bd3a90a0f2ac1fa9c 568 Pfam PF00916 Sulfate permease family 21 388 1.5E-89 T 13-09-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 THL1_RS24675 4137c15ef63a82277b233c541bc3d856 83 SUPERFAMILY SSF47413 7 71 1.5E-11 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS24675 4137c15ef63a82277b233c541bc3d856 83 SMART SM00530 13 68 7.7E-6 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS24675 4137c15ef63a82277b233c541bc3d856 83 Pfam PF01381 Helix-turn-helix 14 65 2.7E-6 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS24675 4137c15ef63a82277b233c541bc3d856 83 Gene3D G3DSA:1.10.260.40 2 69 1.9E-12 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS21350 41d9b70a1c9a1b489eda0ab7c567b652 313 Gene3D G3DSA:3.30.70.1400 14 98 2.4E-29 T 13-09-2016 THL1_RS21350 41d9b70a1c9a1b489eda0ab7c567b652 313 SUPERFAMILY SSF101790 228 306 1.9E-11 T 13-09-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain THL1_RS21350 41d9b70a1c9a1b489eda0ab7c567b652 313 PANTHER PTHR22602:SF0 4 255 1.8E-55 T 13-09-2016 THL1_RS21350 41d9b70a1c9a1b489eda0ab7c567b652 313 PANTHER PTHR22602 4 255 1.8E-55 T 13-09-2016 THL1_RS21350 41d9b70a1c9a1b489eda0ab7c567b652 313 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 171 235 4.1E-27 T 13-09-2016 IPR017703 YgfZ/GcvT conserved site THL1_RS21350 41d9b70a1c9a1b489eda0ab7c567b652 313 Pfam PF01571 Aminomethyltransferase folate-binding domain 10 107 9.1E-5 T 13-09-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal THL1_RS21350 41d9b70a1c9a1b489eda0ab7c567b652 313 SUPERFAMILY SSF103025 3 226 7.22E-55 T 13-09-2016 THL1_RS19075 6e9ffcedfa8ce71d83ac937cdef97b73 473 Pfam PF13520 Amino acid permease 23 429 2.7E-34 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS19075 6e9ffcedfa8ce71d83ac937cdef97b73 473 PIRSF PIRSF006060 4 468 4.8E-74 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS19075 6e9ffcedfa8ce71d83ac937cdef97b73 473 PANTHER PTHR11785 12 438 1.0E-68 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS19075 6e9ffcedfa8ce71d83ac937cdef97b73 473 PANTHER PTHR11785:SF342 12 438 1.0E-68 T 13-09-2016 THL1_RS08335 6cc50647bd61ffb3f7911db0b4451313 137 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 21 37 - T 13-09-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THL1_RS08335 6cc50647bd61ffb3f7911db0b4451313 137 SUPERFAMILY SSF75620 7 104 8.63E-13 T 13-09-2016 THL1_RS08335 6cc50647bd61ffb3f7911db0b4451313 137 PANTHER PTHR11075 5 136 3.6E-44 T 13-09-2016 THL1_RS08335 6cc50647bd61ffb3f7911db0b4451313 137 Gene3D G3DSA:3.30.160.200 6 107 3.5E-35 T 13-09-2016 THL1_RS08335 6cc50647bd61ffb3f7911db0b4451313 137 Pfam PF00472 RF-1 domain 7 132 5.3E-27 T 13-09-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THL1_RS07820 c358120f263ab3266ce5fab8384a378c 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 112 5.0E-24 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS07820 c358120f263ab3266ce5fab8384a378c 223 SUPERFAMILY SSF161098 15 203 1.57E-38 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07820 c358120f263ab3266ce5fab8384a378c 223 Gene3D G3DSA:1.10.3720.10 15 217 8.5E-40 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07820 c358120f263ab3266ce5fab8384a378c 223 PANTHER PTHR30614 1 223 3.0E-68 T 13-09-2016 THL1_RS07820 c358120f263ab3266ce5fab8384a378c 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 217 1.2E-16 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS27155 e5ba6bcd413e5a277d1b8887ed45a2ac 528 PANTHER PTHR38761 2 526 2.4E-266 T 13-09-2016 THL1_RS27155 e5ba6bcd413e5a277d1b8887ed45a2ac 528 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 528 230.474 T 13-09-2016 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255|UniPathway: UPA00142 THL1_RS27155 e5ba6bcd413e5a277d1b8887ed45a2ac 528 SUPERFAMILY SSF55931 7 515 1.44E-195 T 13-09-2016 THL1_RS27155 e5ba6bcd413e5a277d1b8887ed45a2ac 528 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 6 518 7.8E-231 T 13-09-2016 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255|UniPathway: UPA00142 THL1_RS27155 e5ba6bcd413e5a277d1b8887ed45a2ac 528 Pfam PF04262 Glutamate-cysteine ligase 10 381 1.0E-167 T 13-09-2016 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255|UniPathway: UPA00142 THL1_RS20190 70807f268fd4796ad37a73a8f994193b 77 Pfam PF13490 Putative zinc-finger 4 38 1.4E-9 T 13-09-2016 IPR027383 Putative zinc-finger THL1_RS14175 515881cc0e0f994e4ed4ee77d72c43de 744 Pfam PF07731 Multicopper oxidase 617 711 2.8E-16 T 13-09-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 THL1_RS14175 515881cc0e0f994e4ed4ee77d72c43de 744 PANTHER PTHR11709:SF2 329 493 4.7E-43 T 13-09-2016 THL1_RS14175 515881cc0e0f994e4ed4ee77d72c43de 744 PANTHER PTHR11709:SF2 513 741 4.7E-43 T 13-09-2016 THL1_RS14175 515881cc0e0f994e4ed4ee77d72c43de 744 SUPERFAMILY SSF49503 329 356 3.96E-11 T 13-09-2016 IPR008972 Cupredoxin THL1_RS14175 515881cc0e0f994e4ed4ee77d72c43de 744 SUPERFAMILY SSF49503 206 294 3.96E-11 T 13-09-2016 IPR008972 Cupredoxin THL1_RS14175 515881cc0e0f994e4ed4ee77d72c43de 744 SUPERFAMILY SSF49503 610 707 1.35E-19 T 13-09-2016 IPR008972 Cupredoxin THL1_RS14175 515881cc0e0f994e4ed4ee77d72c43de 744 Gene3D G3DSA:2.60.40.420 383 511 5.2E-26 T 13-09-2016 IPR008972 Cupredoxin THL1_RS14175 515881cc0e0f994e4ed4ee77d72c43de 744 PANTHER PTHR11709 513 741 4.7E-43 T 13-09-2016 THL1_RS14175 515881cc0e0f994e4ed4ee77d72c43de 744 PANTHER PTHR11709 329 493 4.7E-43 T 13-09-2016 THL1_RS14175 515881cc0e0f994e4ed4ee77d72c43de 744 SUPERFAMILY SSF49503 385 495 9.93E-18 T 13-09-2016 IPR008972 Cupredoxin THL1_RS14175 515881cc0e0f994e4ed4ee77d72c43de 744 Gene3D G3DSA:2.60.40.420 329 354 5.5E-8 T 13-09-2016 IPR008972 Cupredoxin THL1_RS14175 515881cc0e0f994e4ed4ee77d72c43de 744 Gene3D G3DSA:2.60.40.420 207 294 5.5E-8 T 13-09-2016 IPR008972 Cupredoxin THL1_RS14175 515881cc0e0f994e4ed4ee77d72c43de 744 Gene3D G3DSA:2.60.40.420 611 712 5.5E-23 T 13-09-2016 IPR008972 Cupredoxin THL1_RS00395 9c2c163597983721dbd4f5807dd1772e 645 SMART SM00267 455 625 7.2E-54 T 13-09-2016 IPR000160 GGDEF domain THL1_RS00395 9c2c163597983721dbd4f5807dd1772e 645 PANTHER PTHR10799:SF750 353 622 1.1E-25 T 13-09-2016 THL1_RS00395 9c2c163597983721dbd4f5807dd1772e 645 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 463 625 1.9E-46 T 13-09-2016 IPR000160 GGDEF domain THL1_RS00395 9c2c163597983721dbd4f5807dd1772e 645 Gene3D G3DSA:3.30.70.270 467 626 1.2E-52 T 13-09-2016 THL1_RS00395 9c2c163597983721dbd4f5807dd1772e 645 Pfam PF00990 Diguanylate cyclase, GGDEF domain 465 621 4.2E-44 T 13-09-2016 IPR000160 GGDEF domain THL1_RS00395 9c2c163597983721dbd4f5807dd1772e 645 PANTHER PTHR10799 353 622 1.1E-25 T 13-09-2016 THL1_RS00395 9c2c163597983721dbd4f5807dd1772e 645 SUPERFAMILY SSF55073 470 623 3.37E-47 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS16505 517c178908f80687a3c4bb8f09908636 333 Gene3D G3DSA:1.10.1530.10 3 71 1.8E-18 T 13-09-2016 THL1_RS16505 517c178908f80687a3c4bb8f09908636 333 SUPERFAMILY SSF89733 2 332 2.49E-97 T 13-09-2016 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS16505 517c178908f80687a3c4bb8f09908636 333 PANTHER PTHR11091:SF0 1 277 3.2E-78 T 13-09-2016 THL1_RS16505 517c178908f80687a3c4bb8f09908636 333 Gene3D G3DSA:3.30.1370.60 72 274 8.4E-74 T 13-09-2016 THL1_RS16505 517c178908f80687a3c4bb8f09908636 333 Pfam PF02615 Malate/L-lactate dehydrogenase 6 330 1.7E-95 T 13-09-2016 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS16505 517c178908f80687a3c4bb8f09908636 333 PANTHER PTHR11091 1 277 3.2E-78 T 13-09-2016 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS15720 03f9dbafb69de585029c25c603de356c 436 PANTHER PTHR24095 62 379 4.1E-188 T 13-09-2016 THL1_RS15720 03f9dbafb69de585029c25c603de356c 436 SUPERFAMILY SSF56801 26 402 1.44E-64 T 13-09-2016 THL1_RS15720 03f9dbafb69de585029c25c603de356c 436 Pfam PF00501 AMP-binding enzyme 84 292 3.4E-17 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS15720 03f9dbafb69de585029c25c603de356c 436 Gene3D G3DSA:3.30.300.30 328 435 1.9E-31 T 13-09-2016 THL1_RS15720 03f9dbafb69de585029c25c603de356c 436 PANTHER PTHR24095:SF175 62 379 4.1E-188 T 13-09-2016 THL1_RS15720 03f9dbafb69de585029c25c603de356c 436 Gene3D G3DSA:3.40.50.980 89 252 1.4E-16 T 13-09-2016 THL1_RS15720 03f9dbafb69de585029c25c603de356c 436 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 14 434 3.1E-221 T 13-09-2016 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716|UniPathway: UPA00930 THL1_RS15720 03f9dbafb69de585029c25c603de356c 436 Pfam PF14535 AMP-binding enzyme C-terminal domain 338 434 2.5E-21 T 13-09-2016 IPR028154 AMP-dependent ligase, C-terminal THL1_RS15720 03f9dbafb69de585029c25c603de356c 436 PIRSF PIRSF006444 2 436 9.4E-214 T 13-09-2016 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716|UniPathway: UPA00930 THL1_RS02250 9ac9b5d2283f537bfb258dcbe1b1f584 188 Pfam PF08238 Sel1 repeat 139 173 5.8E-4 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS02250 9ac9b5d2283f537bfb258dcbe1b1f584 188 Pfam PF08238 Sel1 repeat 68 101 3.6E-8 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS02250 9ac9b5d2283f537bfb258dcbe1b1f584 188 PANTHER PTHR11102 55 178 2.8E-16 T 13-09-2016 THL1_RS02250 9ac9b5d2283f537bfb258dcbe1b1f584 188 Gene3D G3DSA:1.25.40.10 56 184 5.4E-22 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS02250 9ac9b5d2283f537bfb258dcbe1b1f584 188 SMART SM00671 67 101 7.9E-7 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS02250 9ac9b5d2283f537bfb258dcbe1b1f584 188 SMART SM00671 139 175 2.0E-5 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS02250 9ac9b5d2283f537bfb258dcbe1b1f584 188 SUPERFAMILY SSF81901 60 179 8.5E-16 T 13-09-2016 THL1_RS05485 10d2e7466b5b8c2b0cc3ddd460f3d28b 146 PIRSF PIRSF006318 2 143 4.6E-33 T 13-09-2016 IPR009386 Protein of unknown function DUF1043 THL1_RS05485 10d2e7466b5b8c2b0cc3ddd460f3d28b 146 Pfam PF06295 Protein of unknown function (DUF1043) 14 129 2.3E-21 T 13-09-2016 IPR009386 Protein of unknown function DUF1043 THL1_RS05485 10d2e7466b5b8c2b0cc3ddd460f3d28b 146 PANTHER PTHR39579 2 146 9.4E-48 T 13-09-2016 THL1_RS09820 9f1e5569e677bfb0458e996205e7c1f9 365 Gene3D G3DSA:3.90.1150.10 246 360 6.4E-26 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS09820 9f1e5569e677bfb0458e996205e7c1f9 365 Gene3D G3DSA:3.40.640.10 11 243 2.3E-88 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS09820 9f1e5569e677bfb0458e996205e7c1f9 365 PANTHER PTHR30244 1 365 2.0E-102 T 13-09-2016 THL1_RS09820 9f1e5569e677bfb0458e996205e7c1f9 365 PANTHER PTHR30244:SF13 1 365 2.0E-102 T 13-09-2016 THL1_RS09820 9f1e5569e677bfb0458e996205e7c1f9 365 SUPERFAMILY SSF53383 11 359 7.8E-112 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS09820 9f1e5569e677bfb0458e996205e7c1f9 365 PIRSF PIRSF000390 1 363 1.7E-101 T 13-09-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THL1_RS09820 9f1e5569e677bfb0458e996205e7c1f9 365 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 14 358 1.1E-116 T 13-09-2016 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THL1_RS28015 3fe7acd79520670601186beee9a71855 305 PANTHER PTHR26402 4 125 1.2E-38 T 13-09-2016 THL1_RS28015 3fe7acd79520670601186beee9a71855 305 Gene3D G3DSA:3.40.50.2300 2 131 6.7E-37 T 13-09-2016 THL1_RS28015 3fe7acd79520670601186beee9a71855 305 SUPERFAMILY SSF52172 1 127 1.31E-35 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS28015 3fe7acd79520670601186beee9a71855 305 Pfam PF00072 Response regulator receiver domain 6 119 3.0E-26 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS28015 3fe7acd79520670601186beee9a71855 305 SMART SM00448 4 119 3.6E-31 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS06495 b757be30af373993d5ddd7d7261e9a3e 308 SUPERFAMILY SSF53474 17 307 7.52E-75 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS06495 b757be30af373993d5ddd7d7261e9a3e 308 PANTHER PTHR23024 45 307 2.0E-99 T 13-09-2016 THL1_RS06495 b757be30af373993d5ddd7d7261e9a3e 308 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 149 161 - T 13-09-2016 IPR033140 Lipase, GDXG, putative serine active site THL1_RS06495 b757be30af373993d5ddd7d7261e9a3e 308 Gene3D G3DSA:3.40.50.1820 2 308 3.6E-101 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS06495 b757be30af373993d5ddd7d7261e9a3e 308 Pfam PF07859 alpha/beta hydrolase fold 77 283 1.9E-77 T 13-09-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 THL1_RS06495 b757be30af373993d5ddd7d7261e9a3e 308 PANTHER PTHR23024:SF207 45 307 2.0E-99 T 13-09-2016 THL1_RS06495 b757be30af373993d5ddd7d7261e9a3e 308 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 77 93 - T 13-09-2016 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 THL1_RS02245 4b8e91a35375686dd56fd4bf56a491ca 695 Pfam PF07715 TonB-dependent Receptor Plug Domain 49 144 5.7E-23 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS02245 4b8e91a35375686dd56fd4bf56a491ca 695 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 678 695 - T 13-09-2016 IPR010917 TonB-dependent receptor, conserved site THL1_RS02245 4b8e91a35375686dd56fd4bf56a491ca 695 PANTHER PTHR32552:SF10 41 695 2.4E-148 T 13-09-2016 THL1_RS02245 4b8e91a35375686dd56fd4bf56a491ca 695 PANTHER PTHR32552:SF10 2 25 2.4E-148 T 13-09-2016 THL1_RS02245 4b8e91a35375686dd56fd4bf56a491ca 695 PANTHER PTHR32552 2 25 2.4E-148 T 13-09-2016 THL1_RS02245 4b8e91a35375686dd56fd4bf56a491ca 695 SUPERFAMILY SSF56935 41 695 7.47E-133 T 13-09-2016 THL1_RS02245 4b8e91a35375686dd56fd4bf56a491ca 695 Gene3D G3DSA:2.170.130.10 30 152 1.2E-37 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS02245 4b8e91a35375686dd56fd4bf56a491ca 695 Pfam PF00593 TonB dependent receptor 457 694 1.9E-33 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS02245 4b8e91a35375686dd56fd4bf56a491ca 695 Gene3D G3DSA:2.40.170.20 160 695 2.5E-139 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS02245 4b8e91a35375686dd56fd4bf56a491ca 695 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 51 695 1.2E-109 T 13-09-2016 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 THL1_RS02245 4b8e91a35375686dd56fd4bf56a491ca 695 PANTHER PTHR32552 41 695 2.4E-148 T 13-09-2016 THL1_RS27380 b39edabbc964fa2cd237ca644a21bfe8 197 TIGRFAM TIGR02722 lp_: uncharacterized lipoprotein 7 193 5.1E-41 T 13-09-2016 IPR014094 Penicillin-binding protein activator LpoB THL1_RS27380 b39edabbc964fa2cd237ca644a21bfe8 197 Pfam PF13036 Peptidoglycan-synthase activator LpoB 9 191 2.4E-55 T 13-09-2016 IPR014094 Penicillin-binding protein activator LpoB THL1_RS27380 b39edabbc964fa2cd237ca644a21bfe8 197 PANTHER PTHR40593 46 194 2.0E-30 T 13-09-2016 THL1_RS16020 60c2ff620b86e9e94b37f2f7cc08da1c 654 SMART SM01358 37 303 1.6E-32 T 13-09-2016 IPR032255 Helical bimodular sensor domain THL1_RS16020 60c2ff620b86e9e94b37f2f7cc08da1c 654 Pfam PF00672 HAMP domain 306 374 1.8E-13 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS16020 60c2ff620b86e9e94b37f2f7cc08da1c 654 SUPERFAMILY SSF58104 345 654 7.32E-78 T 13-09-2016 THL1_RS16020 60c2ff620b86e9e94b37f2f7cc08da1c 654 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 435 652 3.2E-49 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS16020 60c2ff620b86e9e94b37f2f7cc08da1c 654 Gene3D G3DSA:1.10.287.950 407 623 6.2E-59 T 13-09-2016 THL1_RS16020 60c2ff620b86e9e94b37f2f7cc08da1c 654 PANTHER PTHR32089 251 654 1.2E-121 T 13-09-2016 THL1_RS16020 60c2ff620b86e9e94b37f2f7cc08da1c 654 SMART SM00304 325 377 1.4E-12 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS16020 60c2ff620b86e9e94b37f2f7cc08da1c 654 SMART SM00304 378 430 18.0 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS16020 60c2ff620b86e9e94b37f2f7cc08da1c 654 SMART SM00283 392 653 4.5E-83 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS26730 b0b4ffd9e69a88ca0daefa2cacf413a6 251 SMART SM00062 29 251 2.3E-4 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS26730 b0b4ffd9e69a88ca0daefa2cacf413a6 251 SUPERFAMILY SSF53850 30 251 2.26E-37 T 13-09-2016 THL1_RS26730 b0b4ffd9e69a88ca0daefa2cacf413a6 251 PANTHER PTHR38834 1 250 1.1E-123 T 13-09-2016 THL1_RS26730 b0b4ffd9e69a88ca0daefa2cacf413a6 251 PANTHER PTHR38834:SF1 1 250 1.1E-123 T 13-09-2016 THL1_RS26730 b0b4ffd9e69a88ca0daefa2cacf413a6 251 Gene3D G3DSA:3.40.190.10 212 251 6.8E-14 T 13-09-2016 THL1_RS26730 b0b4ffd9e69a88ca0daefa2cacf413a6 251 Gene3D G3DSA:3.40.190.10 31 120 6.8E-14 T 13-09-2016 THL1_RS26730 b0b4ffd9e69a88ca0daefa2cacf413a6 251 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 251 5.6E-22 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS15355 780e40f5f5829af1f94f06856ac4c296 89 PANTHER PTHR33677:SF3 9 89 7.9E-13 T 13-09-2016 THL1_RS15355 780e40f5f5829af1f94f06856ac4c296 89 PANTHER PTHR33677 9 89 7.9E-13 T 13-09-2016 THL1_RS15355 780e40f5f5829af1f94f06856ac4c296 89 Pfam PF02583 Metal-sensitive transcriptional repressor 10 85 6.4E-19 T 13-09-2016 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 THL1_RS17830 977666cdc275ea888019904b286c3102 277 Hamap MF_00297 NADH pyrophosphatase [nudC]. 7 272 49.124 T 13-09-2016 IPR022925 NADH pyrophosphatase NudC GO:0000210 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 THL1_RS17830 977666cdc275ea888019904b286c3102 277 SUPERFAMILY SSF55811 93 262 3.25E-43 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS17830 977666cdc275ea888019904b286c3102 277 PANTHER PTHR22769 100 257 9.9E-61 T 13-09-2016 THL1_RS17830 977666cdc275ea888019904b286c3102 277 Pfam PF00293 NUDIX domain 145 251 1.7E-20 T 13-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 THL1_RS17830 977666cdc275ea888019904b286c3102 277 PANTHER PTHR22769:SF7 100 257 9.9E-61 T 13-09-2016 THL1_RS17830 977666cdc275ea888019904b286c3102 277 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 18 106 8.7E-9 T 13-09-2016 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 THL1_RS17830 977666cdc275ea888019904b286c3102 277 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 109 139 1.9E-9 T 13-09-2016 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381 THL1_RS17830 977666cdc275ea888019904b286c3102 277 ProSitePatterns PS00893 Nudix box signature. 174 195 - T 13-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THL1_RS17830 977666cdc275ea888019904b286c3102 277 SUPERFAMILY SSF55811 6 111 9.01E-23 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS17830 977666cdc275ea888019904b286c3102 277 Gene3D G3DSA:3.90.79.10 101 265 3.2E-45 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS05310 e51d9fcbc261f2c8a865c49fd8b4d476 196 PIRSF PIRSF006305 1 192 1.8E-47 T 13-09-2016 IPR003697 Maf-like protein GO:0005737 THL1_RS05310 e51d9fcbc261f2c8a865c49fd8b4d476 196 Pfam PF02545 Maf-like protein 4 185 2.5E-52 T 13-09-2016 IPR003697 Maf-like protein GO:0005737 THL1_RS05310 e51d9fcbc261f2c8a865c49fd8b4d476 196 Gene3D G3DSA:3.90.950.10 3 189 2.1E-64 T 13-09-2016 IPR029001 Inosine triphosphate pyrophosphatase-like THL1_RS05310 e51d9fcbc261f2c8a865c49fd8b4d476 196 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 184 4.3E-50 T 13-09-2016 IPR003697 Maf-like protein GO:0005737 THL1_RS05310 e51d9fcbc261f2c8a865c49fd8b4d476 196 SUPERFAMILY SSF52972 2 185 9.16E-59 T 13-09-2016 IPR029001 Inosine triphosphate pyrophosphatase-like THL1_RS05310 e51d9fcbc261f2c8a865c49fd8b4d476 196 PANTHER PTHR11746 125 180 7.3E-14 T 13-09-2016 THL1_RS05310 e51d9fcbc261f2c8a865c49fd8b4d476 196 Hamap MF_00528 Septum formation protein Maf [maf]. 3 191 31.77 T 13-09-2016 IPR003697 Maf-like protein GO:0005737 THL1_RS10150 3cd050921dadbed0f487af708d5cbf4b 404 PANTHER PTHR30012 2 404 8.3E-236 T 13-09-2016 THL1_RS10150 3cd050921dadbed0f487af708d5cbf4b 404 Pfam PF00482 Type II secretion system (T2SS), protein F 273 395 4.1E-26 T 13-09-2016 IPR018076 Type II secretion system F domain THL1_RS10150 3cd050921dadbed0f487af708d5cbf4b 404 Pfam PF00482 Type II secretion system (T2SS), protein F 71 193 1.2E-28 T 13-09-2016 IPR018076 Type II secretion system F domain THL1_RS10150 3cd050921dadbed0f487af708d5cbf4b 404 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 403 5.6E-153 T 13-09-2016 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 THL1_RS10150 3cd050921dadbed0f487af708d5cbf4b 404 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 165 193 - T 13-09-2016 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 THL1_RS10150 3cd050921dadbed0f487af708d5cbf4b 404 PANTHER PTHR30012:SF6 2 404 8.3E-236 T 13-09-2016 THL1_RS10150 3cd050921dadbed0f487af708d5cbf4b 404 PRINTS PR00812 Bacterial general secretion pathway protein F signature 384 403 3.7E-35 T 13-09-2016 IPR003004 GspF/PilC family THL1_RS10150 3cd050921dadbed0f487af708d5cbf4b 404 PRINTS PR00812 Bacterial general secretion pathway protein F signature 368 382 3.7E-35 T 13-09-2016 IPR003004 GspF/PilC family THL1_RS10150 3cd050921dadbed0f487af708d5cbf4b 404 PRINTS PR00812 Bacterial general secretion pathway protein F signature 66 78 3.7E-35 T 13-09-2016 IPR003004 GspF/PilC family THL1_RS10150 3cd050921dadbed0f487af708d5cbf4b 404 PRINTS PR00812 Bacterial general secretion pathway protein F signature 165 193 3.7E-35 T 13-09-2016 IPR003004 GspF/PilC family THL1_RS28275 56fa78594cec212e1658ce383597b1b4 135 Gene3D G3DSA:3.40.1580.10 1 134 1.0E-61 T 13-09-2016 IPR018958 SMI1/KNR4-like domain THL1_RS28275 56fa78594cec212e1658ce383597b1b4 135 Pfam PF14567 SMI1-KNR4 cell-wall 1 133 2.0E-44 T 13-09-2016 THL1_RS28275 56fa78594cec212e1658ce383597b1b4 135 SMART SM00860 21 130 8.3E-5 T 13-09-2016 IPR018958 SMI1/KNR4-like domain THL1_RS28275 56fa78594cec212e1658ce383597b1b4 135 SUPERFAMILY SSF160631 1 133 4.84E-43 T 13-09-2016 THL1_RS11655 be3c27f58469c65ea76a837be1cdf33d 380 Pfam PF04116 Fatty acid hydroxylase superfamily 57 209 8.9E-9 T 13-09-2016 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 THL1_RS11655 be3c27f58469c65ea76a837be1cdf33d 380 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 222 365 4.8E-22 T 13-09-2016 IPR019587 Polyketide cyclase/dehydrase THL1_RS11655 be3c27f58469c65ea76a837be1cdf33d 380 Gene3D G3DSA:3.30.530.20 218 366 2.3E-8 T 13-09-2016 IPR023393 START-like domain THL1_RS11655 be3c27f58469c65ea76a837be1cdf33d 380 SUPERFAMILY SSF55961 221 366 1.0E-19 T 13-09-2016 THL1_RS27785 c8d4fde1259edde44245223caa095b4b 383 PANTHER PTHR23521 1 382 2.5E-108 T 13-09-2016 THL1_RS27785 c8d4fde1259edde44245223caa095b4b 383 Pfam PF07690 Major Facilitator Superfamily 12 242 3.0E-17 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS27785 c8d4fde1259edde44245223caa095b4b 383 Gene3D G3DSA:1.20.1250.20 202 368 2.3E-15 T 13-09-2016 THL1_RS27785 c8d4fde1259edde44245223caa095b4b 383 Gene3D G3DSA:1.20.1250.20 5 173 2.2E-18 T 13-09-2016 THL1_RS27785 c8d4fde1259edde44245223caa095b4b 383 PANTHER PTHR23521:SF2 1 382 2.5E-108 T 13-09-2016 THL1_RS27785 c8d4fde1259edde44245223caa095b4b 383 SUPERFAMILY SSF103473 2 369 2.75E-39 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS08620 3c0fe99057adcf47d7b3a72308139932 375 PANTHER PTHR31384:SF26 14 307 7.3E-54 T 13-09-2016 THL1_RS08620 3c0fe99057adcf47d7b3a72308139932 375 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 9 373 6.0E-148 T 13-09-2016 IPR007434 Peptidogalycan biosysnthesis/recognition THL1_RS08620 3c0fe99057adcf47d7b3a72308139932 375 Gene3D G3DSA:3.40.630.30 176 323 1.1E-21 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS08620 3c0fe99057adcf47d7b3a72308139932 375 PANTHER PTHR31384 14 307 7.3E-54 T 13-09-2016 THL1_RS08620 3c0fe99057adcf47d7b3a72308139932 375 SUPERFAMILY SSF55729 175 345 3.66E-40 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS05700 bb3dc3e21e0a861edc079545c9308ffd 314 SUPERFAMILY SSF55811 1 126 2.84E-39 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS05700 bb3dc3e21e0a861edc079545c9308ffd 314 Pfam PF02581 Thiamine monophosphate synthase/TENI 132 309 1.9E-33 T 13-09-2016 IPR003733 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 THL1_RS05700 bb3dc3e21e0a861edc079545c9308ffd 314 PRINTS PR00502 NUDIX hydrolase family signature 47 62 2.6E-7 T 13-09-2016 IPR020476 NUDIX hydrolase THL1_RS05700 bb3dc3e21e0a861edc079545c9308ffd 314 PRINTS PR00502 NUDIX hydrolase family signature 33 47 2.6E-7 T 13-09-2016 IPR020476 NUDIX hydrolase THL1_RS05700 bb3dc3e21e0a861edc079545c9308ffd 314 TIGRFAM TIGR00586 mutt: mutator mutT protein 1 125 1.8E-33 T 13-09-2016 IPR003561 Mutator MutT GO:0006281|GO:0008413 MetaCyc: PWY-6502 THL1_RS05700 bb3dc3e21e0a861edc079545c9308ffd 314 SUPERFAMILY SSF51391 114 312 5.89E-43 T 13-09-2016 IPR022998 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357|UniPathway: UPA00060 THL1_RS05700 bb3dc3e21e0a861edc079545c9308ffd 314 Gene3D G3DSA:3.90.79.10 3 121 5.2E-38 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS05700 bb3dc3e21e0a861edc079545c9308ffd 314 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 13-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THL1_RS05700 bb3dc3e21e0a861edc079545c9308ffd 314 Gene3D G3DSA:3.20.20.70 122 311 8.0E-37 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS05700 bb3dc3e21e0a861edc079545c9308ffd 314 Pfam PF00293 NUDIX domain 3 123 3.0E-19 T 13-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 THL1_RS05700 bb3dc3e21e0a861edc079545c9308ffd 314 PANTHER PTHR22769 1 187 1.5E-51 T 13-09-2016 THL1_RS05700 bb3dc3e21e0a861edc079545c9308ffd 314 PANTHER PTHR22769:SF35 1 187 1.5E-51 T 13-09-2016 THL1_RS08950 00e74f39bcec541ed771aa638dbcfd5b 393 Gene3D G3DSA:3.30.1540.10 232 301 6.3E-12 T 13-09-2016 THL1_RS08950 00e74f39bcec541ed771aa638dbcfd5b 393 PANTHER PTHR24023 60 380 1.3E-58 T 13-09-2016 THL1_RS08950 00e74f39bcec541ed771aa638dbcfd5b 393 Pfam PF02515 CoA-transferase family III 5 369 1.5E-102 T 13-09-2016 IPR003673 CoA-transferase family III GO:0003824 THL1_RS08950 00e74f39bcec541ed771aa638dbcfd5b 393 PANTHER PTHR24023:SF577 60 380 1.3E-58 T 13-09-2016 THL1_RS08950 00e74f39bcec541ed771aa638dbcfd5b 393 SUPERFAMILY SSF89796 3 392 2.35E-126 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS08950 00e74f39bcec541ed771aa638dbcfd5b 393 Gene3D G3DSA:3.40.50.10540 302 392 4.3E-109 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS08950 00e74f39bcec541ed771aa638dbcfd5b 393 Gene3D G3DSA:3.40.50.10540 2 216 4.3E-109 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS22525 f1e446b2226a6d0b23891a24b0ec99b6 304 Gene3D G3DSA:1.10.10.10 5 88 1.3E-28 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS22525 f1e446b2226a6d0b23891a24b0ec99b6 304 SUPERFAMILY SSF46785 4 88 3.29E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS22525 f1e446b2226a6d0b23891a24b0ec99b6 304 PANTHER PTHR30537:SF10 1 304 2.5E-167 T 13-09-2016 THL1_RS22525 f1e446b2226a6d0b23891a24b0ec99b6 304 Pfam PF03466 LysR substrate binding domain 88 285 9.1E-50 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS22525 f1e446b2226a6d0b23891a24b0ec99b6 304 Gene3D G3DSA:3.40.190.10 92 176 3.4E-25 T 13-09-2016 THL1_RS22525 f1e446b2226a6d0b23891a24b0ec99b6 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 63 2.3E-22 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS22525 f1e446b2226a6d0b23891a24b0ec99b6 304 Gene3D G3DSA:3.40.190.10 177 255 2.7E-23 T 13-09-2016 THL1_RS22525 f1e446b2226a6d0b23891a24b0ec99b6 304 SUPERFAMILY SSF53850 89 289 2.17E-49 T 13-09-2016 THL1_RS22525 f1e446b2226a6d0b23891a24b0ec99b6 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.3E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS22525 f1e446b2226a6d0b23891a24b0ec99b6 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.3E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS22525 f1e446b2226a6d0b23891a24b0ec99b6 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.3E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS22525 f1e446b2226a6d0b23891a24b0ec99b6 304 PANTHER PTHR30537 1 304 2.5E-167 T 13-09-2016 THL1_RS13505 35f3c30c8dcc395cbeea26a97eb130a4 257 PANTHER PTHR35272 21 253 1.2E-116 T 13-09-2016 THL1_RS13505 35f3c30c8dcc395cbeea26a97eb130a4 257 SUPERFAMILY SSF52833 94 253 8.59E-37 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS13505 35f3c30c8dcc395cbeea26a97eb130a4 257 PANTHER PTHR35272:SF2 21 253 1.2E-116 T 13-09-2016 THL1_RS13505 35f3c30c8dcc395cbeea26a97eb130a4 257 SUPERFAMILY SSF54423 26 84 2.49E-19 T 13-09-2016 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal THL1_RS13505 35f3c30c8dcc395cbeea26a97eb130a4 257 Pfam PF13098 Thioredoxin-like domain 121 250 9.8E-16 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS13505 35f3c30c8dcc395cbeea26a97eb130a4 257 Gene3D G3DSA:3.40.30.10 113 254 4.7E-36 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS12970 eb52c9fde5b0f5e0e562f9d8173581fd 149 SUPERFAMILY SSF159888 29 137 5.36E-19 T 13-09-2016 THL1_RS12970 eb52c9fde5b0f5e0e562f9d8173581fd 149 Pfam PF08818 Domain of unknown function (DU1801) 38 132 6.2E-21 T 13-09-2016 IPR014922 Domain of unknown function DUF1801 THL1_RS08010 ab3a1da7f6b4f2b1b10c012d86f0d5fb 293 Gene3D G3DSA:3.40.50.1820 5 272 2.4E-33 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS08010 ab3a1da7f6b4f2b1b10c012d86f0d5fb 293 Pfam PF00561 alpha/beta hydrolase fold 29 253 2.4E-9 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS08010 ab3a1da7f6b4f2b1b10c012d86f0d5fb 293 SUPERFAMILY SSF53474 13 272 6.67E-36 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS08010 ab3a1da7f6b4f2b1b10c012d86f0d5fb 293 PANTHER PTHR10992 2 192 7.7E-27 T 13-09-2016 THL1_RS08010 ab3a1da7f6b4f2b1b10c012d86f0d5fb 293 PANTHER PTHR10992 208 274 7.7E-27 T 13-09-2016 THL1_RS07810 6baa2936e49a2b8f3f88745616741371 281 SUPERFAMILY SSF53850 36 268 1.63E-39 T 13-09-2016 THL1_RS07810 6baa2936e49a2b8f3f88745616741371 281 Gene3D G3DSA:3.40.190.10 41 164 2.5E-27 T 13-09-2016 THL1_RS07810 6baa2936e49a2b8f3f88745616741371 281 PANTHER PTHR18966 40 268 4.2E-14 T 13-09-2016 THL1_RS07810 6baa2936e49a2b8f3f88745616741371 281 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 268 5.2E-32 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS07810 6baa2936e49a2b8f3f88745616741371 281 SMART SM00062 44 273 1.7E-28 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS07810 6baa2936e49a2b8f3f88745616741371 281 Gene3D G3DSA:3.40.190.10 165 217 5.3E-4 T 13-09-2016 THL1_RS07810 6baa2936e49a2b8f3f88745616741371 281 PANTHER PTHR18966:SF191 40 268 4.2E-14 T 13-09-2016 THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 ProSitePatterns PS00755 Protein secY signature 1. 75 94 - T 13-09-2016 IPR030659 SecY conserved site THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 PANTHER PTHR10906:SF2 16 442 8.0E-224 T 13-09-2016 THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 74 94 5.4E-90 T 13-09-2016 THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 175 198 5.4E-90 T 13-09-2016 THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 267 286 5.4E-90 T 13-09-2016 THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 5.4E-90 T 13-09-2016 THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 149 174 5.4E-90 T 13-09-2016 THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 5.4E-90 T 13-09-2016 THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 22 40 5.4E-90 T 13-09-2016 THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 115 138 5.4E-90 T 13-09-2016 THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 PRINTS PR00303 Preprotein translocase SecY subunit signature 397 415 5.4E-90 T 13-09-2016 THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 PIRSF PIRSF004557 8 436 1.7E-118 T 13-09-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 Gene3D G3DSA:1.10.3370.10 15 432 2.9E-160 T 13-09-2016 IPR023201 SecY subunit domain THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 PANTHER PTHR10906 16 442 8.0E-224 T 13-09-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 21 424 4.1E-128 T 13-09-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 SUPERFAMILY SSF103491 15 419 3.66E-128 T 13-09-2016 IPR023201 SecY subunit domain THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 Hamap MF_01465 Protein translocase subunit SecY [secY]. 9 428 28.884 T 13-09-2016 IPR026593 Protein translocase subunit SecY THL1_RS03625 dfa736c43f5a25651c75e3761cd2ebe9 442 Pfam PF00344 SecY translocase 75 412 2.1E-114 T 13-09-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 THL1_RS15520 f456d0c4201f2559760f0451eed8570d 786 Gene3D G3DSA:1.20.1640.10 194 383 1.4E-29 T 13-09-2016 THL1_RS15520 f456d0c4201f2559760f0451eed8570d 786 Gene3D G3DSA:1.20.1640.10 574 775 3.9E-32 T 13-09-2016 THL1_RS15520 f456d0c4201f2559760f0451eed8570d 786 PRINTS PR00702 Acriflavin resistance protein family signature 668 692 5.4E-7 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15520 f456d0c4201f2559760f0451eed8570d 786 PRINTS PR00702 Acriflavin resistance protein family signature 327 351 5.4E-7 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15520 f456d0c4201f2559760f0451eed8570d 786 PRINTS PR00702 Acriflavin resistance protein family signature 743 766 5.4E-7 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15520 f456d0c4201f2559760f0451eed8570d 786 PRINTS PR00702 Acriflavin resistance protein family signature 614 637 5.4E-7 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS15520 f456d0c4201f2559760f0451eed8570d 786 SUPERFAMILY SSF82866 189 383 1.31E-28 T 13-09-2016 THL1_RS15520 f456d0c4201f2559760f0451eed8570d 786 Pfam PF03176 MMPL family 569 769 1.8E-18 T 13-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 THL1_RS15520 f456d0c4201f2559760f0451eed8570d 786 Pfam PF03176 MMPL family 196 439 4.0E-6 T 13-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 THL1_RS15520 f456d0c4201f2559760f0451eed8570d 786 SUPERFAMILY SSF82866 571 770 2.35E-34 T 13-09-2016 THL1_RS15520 f456d0c4201f2559760f0451eed8570d 786 PANTHER PTHR33406 1 98 1.1E-42 T 13-09-2016 THL1_RS15520 f456d0c4201f2559760f0451eed8570d 786 PANTHER PTHR33406 132 770 1.1E-42 T 13-09-2016 THL1_RS02710 175d2b4ab363f694ddb4deae61418629 218 Pfam PF11726 Protein of unknown function (DUF3296) 38 216 1.1E-48 T 13-09-2016 IPR021723 Inovirus Gp2 THL1_RS19485 b4be3e3aecd890a57954bc2bc5bbbf99 246 PANTHER PTHR30433 2 246 2.0E-119 T 13-09-2016 THL1_RS19485 b4be3e3aecd890a57954bc2bc5bbbf99 246 PANTHER PTHR30433:SF3 2 246 2.0E-119 T 13-09-2016 IPR022522 Flagellar motor stator, MotA THL1_RS19485 b4be3e3aecd890a57954bc2bc5bbbf99 246 Pfam PF01618 MotA/TolQ/ExbB proton channel family 102 219 9.9E-26 T 13-09-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 THL1_RS09375 6d4478cf84f803c4dfc80a0aac19052e 390 SMART SM00267 212 390 1.3E-59 T 13-09-2016 IPR000160 GGDEF domain THL1_RS09375 6d4478cf84f803c4dfc80a0aac19052e 390 SUPERFAMILY SSF55073 228 389 3.3E-48 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS09375 6d4478cf84f803c4dfc80a0aac19052e 390 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 221 389 8.9E-49 T 13-09-2016 IPR000160 GGDEF domain THL1_RS09375 6d4478cf84f803c4dfc80a0aac19052e 390 Pfam PF00990 Diguanylate cyclase, GGDEF domain 223 387 2.7E-50 T 13-09-2016 IPR000160 GGDEF domain THL1_RS09375 6d4478cf84f803c4dfc80a0aac19052e 390 Gene3D G3DSA:3.30.70.270 225 389 8.3E-55 T 13-09-2016 THL1_RS09375 6d4478cf84f803c4dfc80a0aac19052e 390 PANTHER PTHR10799:SF750 213 388 1.6E-35 T 13-09-2016 THL1_RS09375 6d4478cf84f803c4dfc80a0aac19052e 390 PANTHER PTHR10799 213 388 1.6E-35 T 13-09-2016 THL1_RS17015 faa5e6c0bc0ddc91b47fef546fae1dd1 123 SUPERFAMILY SSF46955 50 103 7.14E-7 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS17015 faa5e6c0bc0ddc91b47fef546fae1dd1 123 Pfam PF12728 Helix-turn-helix domain 51 101 1.8E-7 T 13-09-2016 THL1_RS17015 faa5e6c0bc0ddc91b47fef546fae1dd1 123 Gene3D G3DSA:1.10.10.10 50 104 4.5E-4 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS18665 3b17e7f8c2c30c85e57cae49c250ac15 60 Pfam PF01783 Ribosomal L32p protein family 2 56 9.5E-21 T 13-09-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 THL1_RS18665 3b17e7f8c2c30c85e57cae49c250ac15 60 PANTHER PTHR35534 1 60 6.1E-30 T 13-09-2016 THL1_RS18665 3b17e7f8c2c30c85e57cae49c250ac15 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 17.068 T 13-09-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 THL1_RS18665 3b17e7f8c2c30c85e57cae49c250ac15 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 54 8.4E-20 T 13-09-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 THL1_RS18665 3b17e7f8c2c30c85e57cae49c250ac15 60 SUPERFAMILY SSF57829 2 55 3.85E-18 T 13-09-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 THL1_RS04330 53685bee5179213c6ea154aa6d983d1e 107 Pfam PF08850 Domain of unknown function (DUF1820) 7 102 4.3E-44 T 13-09-2016 IPR014949 Protein of unknown function DUF1820 THL1_RS04330 53685bee5179213c6ea154aa6d983d1e 107 PIRSF PIRSF028538 1 107 3.2E-51 T 13-09-2016 IPR014949 Protein of unknown function DUF1820 THL1_RS13385 e9c3133cfe381ea08de7041a4ef1ccab 138 Gene3D G3DSA:2.20.25.10 3 46 6.9E-18 T 13-09-2016 THL1_RS13385 e9c3133cfe381ea08de7041a4ef1ccab 138 SUPERFAMILY SSF82784 5 137 5.23E-42 T 13-09-2016 IPR003718 OsmC/Ohr family THL1_RS13385 e9c3133cfe381ea08de7041a4ef1ccab 138 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 8 136 1.1E-48 T 13-09-2016 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 THL1_RS13385 e9c3133cfe381ea08de7041a4ef1ccab 138 Pfam PF02566 OsmC-like protein 39 135 1.5E-18 T 13-09-2016 IPR003718 OsmC/Ohr family THL1_RS13385 e9c3133cfe381ea08de7041a4ef1ccab 138 PANTHER PTHR33797:SF3 2 131 5.1E-57 T 13-09-2016 THL1_RS13385 e9c3133cfe381ea08de7041a4ef1ccab 138 PANTHER PTHR33797 2 131 5.1E-57 T 13-09-2016 THL1_RS13385 e9c3133cfe381ea08de7041a4ef1ccab 138 Gene3D G3DSA:3.30.300.20 47 137 1.4E-33 T 13-09-2016 IPR015946 K homology domain-like, alpha/beta THL1_RS09570 9358706fd6066ee17b1e6b0789d4445a 267 Pfam PF08666 SAF domain 42 101 6.6E-8 T 13-09-2016 IPR013974 SAF domain THL1_RS09570 9358706fd6066ee17b1e6b0789d4445a 267 SMART SM00858 40 102 2.4E-8 T 13-09-2016 IPR013974 SAF domain THL1_RS09570 9358706fd6066ee17b1e6b0789d4445a 267 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 7 261 1.9E-69 T 13-09-2016 IPR017592 Pilus assembly, Flp-type CpaB THL1_RS09570 9358706fd6066ee17b1e6b0789d4445a 267 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 109 212 8.3E-30 T 13-09-2016 IPR031571 Flp pilus assembly protein RcpC/CpaB domain THL1_RS07360 a464cf41217a0c4cfe49a4e05cee698d 257 PANTHER PTHR26402 199 255 8.6E-23 T 13-09-2016 THL1_RS07360 a464cf41217a0c4cfe49a4e05cee698d 257 SUPERFAMILY SSF46894 189 255 4.76E-19 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS07360 a464cf41217a0c4cfe49a4e05cee698d 257 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 213 229 7.4E-12 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07360 a464cf41217a0c4cfe49a4e05cee698d 257 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 199 213 7.4E-12 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07360 a464cf41217a0c4cfe49a4e05cee698d 257 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 229 241 7.4E-12 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07360 a464cf41217a0c4cfe49a4e05cee698d 257 ProSitePatterns PS00622 LuxR-type HTH domain signature. 213 240 - T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07360 a464cf41217a0c4cfe49a4e05cee698d 257 SMART SM00421 196 253 4.4E-20 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07360 a464cf41217a0c4cfe49a4e05cee698d 257 Pfam PF00196 Bacterial regulatory proteins, luxR family 198 251 1.3E-18 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS07360 a464cf41217a0c4cfe49a4e05cee698d 257 Gene3D G3DSA:1.10.10.10 198 255 1.1E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07360 a464cf41217a0c4cfe49a4e05cee698d 257 PANTHER PTHR26402:SF572 199 255 8.6E-23 T 13-09-2016 THL1_RS03120 672de0459d754fc114363d1b531bf80c 135 PANTHER PTHR30007:SF22 1 134 7.7E-35 T 13-09-2016 THL1_RS03120 672de0459d754fc114363d1b531bf80c 135 PANTHER PTHR30007 1 134 7.7E-35 T 13-09-2016 THL1_RS03120 672de0459d754fc114363d1b531bf80c 135 Pfam PF13586 Transposase DDE domain 50 134 7.4E-21 T 13-09-2016 IPR025668 Transposase DDE domain THL1_RS08060 f2286230f4a4bb4d92235dfd01c20424 437 Gene3D G3DSA:3.50.50.60 185 264 2.3E-45 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS08060 f2286230f4a4bb4d92235dfd01c20424 437 Gene3D G3DSA:3.50.50.60 356 406 2.3E-45 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS08060 f2286230f4a4bb4d92235dfd01c20424 437 Gene3D G3DSA:3.50.50.60 24 131 2.3E-45 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS08060 f2286230f4a4bb4d92235dfd01c20424 437 SUPERFAMILY SSF51905 38 265 5.61E-39 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS08060 f2286230f4a4bb4d92235dfd01c20424 437 SUPERFAMILY SSF51905 356 414 5.61E-39 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS08060 f2286230f4a4bb4d92235dfd01c20424 437 Pfam PF01266 FAD dependent oxidoreductase 39 392 4.4E-49 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS08060 f2286230f4a4bb4d92235dfd01c20424 437 PANTHER PTHR13847 1 434 1.6E-269 T 13-09-2016 THL1_RS08060 f2286230f4a4bb4d92235dfd01c20424 437 PANTHER PTHR13847:SF215 1 434 1.6E-269 T 13-09-2016 THL1_RS02300 15f09590836ba23178f632d9cec69b54 462 PANTHER PTHR30354 1 462 4.6E-185 T 13-09-2016 THL1_RS02300 15f09590836ba23178f632d9cec69b54 462 Pfam PF02447 GntP family permease 5 455 3.4E-9 T 13-09-2016 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 THL1_RS02300 15f09590836ba23178f632d9cec69b54 462 PANTHER PTHR30354:SF7 1 462 4.6E-185 T 13-09-2016 THL1_RS07585 acaca38e49b5fa621bb664933972334d 476 PANTHER PTHR24423:SF533 219 472 2.9E-42 T 13-09-2016 THL1_RS07585 acaca38e49b5fa621bb664933972334d 476 PANTHER PTHR24423 219 472 2.9E-42 T 13-09-2016 THL1_RS07585 acaca38e49b5fa621bb664933972334d 476 SUPERFAMILY SSF55874 333 473 5.89E-28 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS07585 acaca38e49b5fa621bb664933972334d 476 SMART SM00304 221 273 3.0E-10 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS07585 acaca38e49b5fa621bb664933972334d 476 Pfam PF00512 His Kinase A (phospho-acceptor) domain 275 328 2.5E-7 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS07585 acaca38e49b5fa621bb664933972334d 476 Pfam PF00672 HAMP domain 202 269 1.0E-12 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS07585 acaca38e49b5fa621bb664933972334d 476 SMART SM00388 274 332 1.5E-4 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS07585 acaca38e49b5fa621bb664933972334d 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 418 1.9E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS07585 acaca38e49b5fa621bb664933972334d 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 453 1.9E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS07585 acaca38e49b5fa621bb664933972334d 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 432 1.9E-9 T 13-09-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 THL1_RS07585 acaca38e49b5fa621bb664933972334d 476 SMART SM00387 370 475 2.3E-25 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS07585 acaca38e49b5fa621bb664933972334d 476 PANTHER PTHR24423 1 9 2.9E-42 T 13-09-2016 THL1_RS07585 acaca38e49b5fa621bb664933972334d 476 Gene3D G3DSA:1.10.287.130 264 316 1.3E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS07585 acaca38e49b5fa621bb664933972334d 476 SUPERFAMILY SSF47384 258 312 8.44E-11 T 13-09-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THL1_RS07585 acaca38e49b5fa621bb664933972334d 476 Gene3D G3DSA:3.30.565.10 317 474 1.6E-27 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS07585 acaca38e49b5fa621bb664933972334d 476 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 371 473 1.7E-17 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS07585 acaca38e49b5fa621bb664933972334d 476 PANTHER PTHR24423:SF533 1 9 2.9E-42 T 13-09-2016 THL1_RS24305 e6445fb8ae3d151b70670278b139f29b 266 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 5 264 1.3E-103 T 13-09-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 THL1_RS24305 e6445fb8ae3d151b70670278b139f29b 266 PIRSF PIRSF000388 2 266 7.1E-100 T 13-09-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 THL1_RS24305 e6445fb8ae3d151b70670278b139f29b 266 SUPERFAMILY SSF51621 4 264 6.28E-103 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS24305 e6445fb8ae3d151b70670278b139f29b 266 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 264 42.296 T 13-09-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 THL1_RS24305 e6445fb8ae3d151b70670278b139f29b 266 PANTHER PTHR20881 1 264 7.8E-169 T 13-09-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 THL1_RS24305 e6445fb8ae3d151b70670278b139f29b 266 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 259 6.2E-107 T 13-09-2016 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654|UniPathway: UPA00028 THL1_RS24305 e6445fb8ae3d151b70670278b139f29b 266 PANTHER PTHR20881:SF3 1 264 7.8E-169 T 13-09-2016 THL1_RS24305 e6445fb8ae3d151b70670278b139f29b 266 Gene3D G3DSA:3.20.20.60 3 264 1.0E-110 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS23750 4d7e40d2d07beea7f83db75898ae3133 515 Pfam PF06980 Protein of unknown function (DUF1302) 365 515 6.7E-28 T 13-09-2016 IPR010727 Protein of unknown function DUF1302 THL1_RS23750 4d7e40d2d07beea7f83db75898ae3133 515 Pfam PF06980 Protein of unknown function (DUF1302) 33 366 2.3E-98 T 13-09-2016 IPR010727 Protein of unknown function DUF1302 THL1_RS10140 dcea82635ec6943d22e80059f133ca47 214 Pfam PF11356 Type II secretion system protein C 20 148 9.8E-21 T 13-09-2016 IPR024961 Type II secretion system protein C, N-terminal THL1_RS23015 94c1c240c9926b3a4cbbac8843f0b716 140 Gene3D G3DSA:3.30.70.1060 1 117 3.2E-39 T 13-09-2016 THL1_RS23015 94c1c240c9926b3a4cbbac8843f0b716 140 PANTHER PTHR35174 2 140 1.5E-70 T 13-09-2016 THL1_RS23015 94c1c240c9926b3a4cbbac8843f0b716 140 PANTHER PTHR35174:SF1 2 140 1.5E-70 T 13-09-2016 THL1_RS23015 94c1c240c9926b3a4cbbac8843f0b716 140 Pfam PF03795 YCII-related domain 1 114 4.1E-24 T 13-09-2016 IPR005545 YCII-related THL1_RS23015 94c1c240c9926b3a4cbbac8843f0b716 140 SUPERFAMILY SSF54909 1 118 4.02E-35 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS12530 488385c9b3c42bbc63c1c8cc1783bf2e 279 Pfam PF00483 Nucleotidyl transferase 9 266 9.0E-30 T 13-09-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 THL1_RS12530 488385c9b3c42bbc63c1c8cc1783bf2e 279 Gene3D G3DSA:3.90.550.10 3 268 4.7E-64 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS12530 488385c9b3c42bbc63c1c8cc1783bf2e 279 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 2 264 3.3E-120 T 13-09-2016 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 THL1_RS12530 488385c9b3c42bbc63c1c8cc1783bf2e 279 SUPERFAMILY SSF53448 2 270 1.28E-62 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS12530 488385c9b3c42bbc63c1c8cc1783bf2e 279 PANTHER PTHR22572 4 277 1.0E-100 T 13-09-2016 THL1_RS12530 488385c9b3c42bbc63c1c8cc1783bf2e 279 PANTHER PTHR22572:SF14 4 277 1.0E-100 T 13-09-2016 THL1_RS14105 2e3d71cf0e31b36ef87d5668c44659f5 125 PANTHER PTHR11715 2 122 4.8E-58 T 13-09-2016 IPR002930 Glycine cleavage system H-protein THL1_RS14105 2e3d71cf0e31b36ef87d5668c44659f5 125 SUPERFAMILY SSF51230 4 122 3.14E-38 T 13-09-2016 IPR011053 Single hybrid motif THL1_RS14105 2e3d71cf0e31b36ef87d5668c44659f5 125 Gene3D G3DSA:2.40.50.100 4 122 6.7E-44 T 13-09-2016 THL1_RS14105 2e3d71cf0e31b36ef87d5668c44659f5 125 Pfam PF01597 Glycine cleavage H-protein 4 122 4.7E-39 T 13-09-2016 IPR002930 Glycine cleavage system H-protein THL1_RS14105 2e3d71cf0e31b36ef87d5668c44659f5 125 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 4 123 2.6E-43 T 13-09-2016 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 THL1_RS14105 2e3d71cf0e31b36ef87d5668c44659f5 125 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 1 122 27.86 T 13-09-2016 IPR002930 Glycine cleavage system H-protein THL1_RS06945 0dd26e73707f85f6a92241387ef9a528 321 PANTHER PTHR22911:SF55 11 317 4.1E-88 T 13-09-2016 THL1_RS06945 0dd26e73707f85f6a92241387ef9a528 321 PANTHER PTHR22911 11 317 4.1E-88 T 13-09-2016 THL1_RS06945 0dd26e73707f85f6a92241387ef9a528 321 SUPERFAMILY SSF103481 44 144 6.02E-10 T 13-09-2016 THL1_RS06945 0dd26e73707f85f6a92241387ef9a528 321 Pfam PF00892 EamA-like transporter family 161 299 1.4E-11 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS06945 0dd26e73707f85f6a92241387ef9a528 321 Pfam PF00892 EamA-like transporter family 10 143 1.2E-18 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS11355 9d5bb8a0aa42e83661f2f3d96056fa2b 714 PANTHER PTHR23309:SF19 5 714 0.0 T 13-09-2016 THL1_RS11355 9d5bb8a0aa42e83661f2f3d96056fa2b 714 SUPERFAMILY SSF48179 498 640 2.38E-20 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS11355 9d5bb8a0aa42e83661f2f3d96056fa2b 714 Gene3D G3DSA:3.90.226.10 2 205 5.2E-53 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS11355 9d5bb8a0aa42e83661f2f3d96056fa2b 714 SUPERFAMILY SSF52096 3 297 1.15E-60 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS11355 9d5bb8a0aa42e83661f2f3d96056fa2b 714 Gene3D G3DSA:1.10.1040.10 636 712 1.1E-12 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS11355 9d5bb8a0aa42e83661f2f3d96056fa2b 714 SUPERFAMILY SSF51735 316 497 1.63E-54 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11355 9d5bb8a0aa42e83661f2f3d96056fa2b 714 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 204 1.7E-29 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS11355 9d5bb8a0aa42e83661f2f3d96056fa2b 714 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 499 599 1.3E-16 T 13-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS11355 9d5bb8a0aa42e83661f2f3d96056fa2b 714 Gene3D G3DSA:3.40.50.720 310 500 1.1E-53 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11355 9d5bb8a0aa42e83661f2f3d96056fa2b 714 Gene3D G3DSA:1.10.1040.10 501 600 7.0E-15 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS11355 9d5bb8a0aa42e83661f2f3d96056fa2b 714 PANTHER PTHR23309 5 714 0.0 T 13-09-2016 THL1_RS11355 9d5bb8a0aa42e83661f2f3d96056fa2b 714 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 318 496 1.5E-58 T 13-09-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS11355 9d5bb8a0aa42e83661f2f3d96056fa2b 714 SUPERFAMILY SSF48179 624 714 4.0E-19 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS14585 a7bfbded796661d4a16c6b3636304c85 500 PANTHER PTHR11699 1 499 4.5E-244 T 13-09-2016 THL1_RS14585 a7bfbded796661d4a16c6b3636304c85 500 PANTHER PTHR11699:SF210 1 499 4.5E-244 T 13-09-2016 THL1_RS14585 a7bfbded796661d4a16c6b3636304c85 500 Gene3D G3DSA:3.40.309.10 282 469 6.1E-68 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS14585 a7bfbded796661d4a16c6b3636304c85 500 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 267 274 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS14585 a7bfbded796661d4a16c6b3636304c85 500 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 296 307 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS14585 a7bfbded796661d4a16c6b3636304c85 500 SUPERFAMILY SSF53720 18 498 3.14E-164 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS14585 a7bfbded796661d4a16c6b3636304c85 500 Gene3D G3DSA:3.40.605.10 21 281 8.6E-91 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS14585 a7bfbded796661d4a16c6b3636304c85 500 Pfam PF00171 Aldehyde dehydrogenase family 30 494 7.9E-167 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS23070 e9a540ef7c8b4d60c24696685d3b94cc 116 ProSitePatterns PS01015 Ribosomal protein L19 signature. 87 102 - T 13-09-2016 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS23070 e9a540ef7c8b4d60c24696685d3b94cc 116 Pfam PF01245 Ribosomal protein L19 5 114 3.2E-49 T 13-09-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS23070 e9a540ef7c8b4d60c24696685d3b94cc 116 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 3 115 29.679 T 13-09-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS23070 e9a540ef7c8b4d60c24696685d3b94cc 116 PIRSF PIRSF002191 1 116 5.7E-49 T 13-09-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS23070 e9a540ef7c8b4d60c24696685d3b94cc 116 PANTHER PTHR15680 1 115 1.6E-54 T 13-09-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS23070 e9a540ef7c8b4d60c24696685d3b94cc 116 PRINTS PR00061 Ribosomal protein L19 signature 35 64 9.1E-40 T 13-09-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS23070 e9a540ef7c8b4d60c24696685d3b94cc 116 PRINTS PR00061 Ribosomal protein L19 signature 5 34 9.1E-40 T 13-09-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS23070 e9a540ef7c8b4d60c24696685d3b94cc 116 PRINTS PR00061 Ribosomal protein L19 signature 89 114 9.1E-40 T 13-09-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS23070 e9a540ef7c8b4d60c24696685d3b94cc 116 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 4 114 2.6E-49 T 13-09-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS23070 e9a540ef7c8b4d60c24696685d3b94cc 116 SUPERFAMILY SSF50104 2 114 8.32E-45 T 13-09-2016 IPR008991 Translation protein SH3-like domain THL1_RS17380 26298175fb269c3c7cfa443209b6133a 534 PANTHER PTHR30047:SF5 1 504 1.6E-211 T 13-09-2016 THL1_RS17380 26298175fb269c3c7cfa443209b6133a 534 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 49 492 1.5E-129 T 13-09-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 THL1_RS17380 26298175fb269c3c7cfa443209b6133a 534 PANTHER PTHR30047 1 504 1.6E-211 T 13-09-2016 THL1_RS17380 26298175fb269c3c7cfa443209b6133a 534 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 6 492 9.2E-114 T 13-09-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 THL1_RS22455 05c92a0a387811913d8a11af0af3387c 154 Gene3D G3DSA:1.10.10.10 57 102 7.2E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS22455 05c92a0a387811913d8a11af0af3387c 154 Pfam PF02631 RecX family 33 149 2.2E-33 T 13-09-2016 IPR003783 Regulatory protein RecX GO:0006282 THL1_RS22455 05c92a0a387811913d8a11af0af3387c 154 PANTHER PTHR33602 1 154 9.3E-44 T 13-09-2016 THL1_RS22455 05c92a0a387811913d8a11af0af3387c 154 Gene3D G3DSA:1.10.10.10 103 154 7.7E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS22455 05c92a0a387811913d8a11af0af3387c 154 PANTHER PTHR33602:SF1 1 154 9.3E-44 T 13-09-2016 THL1_RS22455 05c92a0a387811913d8a11af0af3387c 154 Hamap MF_01114 Regulatory protein RecX [recX]. 6 154 14.033 T 13-09-2016 IPR003783 Regulatory protein RecX GO:0006282 THL1_RS22455 05c92a0a387811913d8a11af0af3387c 154 Gene3D G3DSA:1.10.10.10 11 56 8.7E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS14690 b02eca98ef48c05c373ecd54f40384bb 233 PANTHER PTHR24322 15 130 9.5E-27 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14690 b02eca98ef48c05c373ecd54f40384bb 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 6.2E-9 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14690 b02eca98ef48c05c373ecd54f40384bb 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 6.2E-9 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14690 b02eca98ef48c05c373ecd54f40384bb 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 6.2E-9 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14690 b02eca98ef48c05c373ecd54f40384bb 233 Gene3D G3DSA:3.40.50.720 11 233 3.4E-37 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS14690 b02eca98ef48c05c373ecd54f40384bb 233 PANTHER PTHR24322:SF540 15 130 9.5E-27 T 13-09-2016 THL1_RS14690 b02eca98ef48c05c373ecd54f40384bb 233 PANTHER PTHR24322:SF540 149 183 9.5E-27 T 13-09-2016 THL1_RS14690 b02eca98ef48c05c373ecd54f40384bb 233 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 37 171 1.6E-12 T 13-09-2016 THL1_RS14690 b02eca98ef48c05c373ecd54f40384bb 233 PANTHER PTHR24322 149 183 9.5E-27 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14690 b02eca98ef48c05c373ecd54f40384bb 233 SUPERFAMILY SSF51735 13 233 4.11E-40 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS06590 cef625d977e7b186011c16fd7906a95b 196 SUPERFAMILY SSF51206 21 149 2.36E-22 T 13-09-2016 IPR018490 Cyclic nucleotide-binding-like THL1_RS06590 cef625d977e7b186011c16fd7906a95b 196 PANTHER PTHR24567 1 190 1.6E-22 T 13-09-2016 THL1_RS06590 cef625d977e7b186011c16fd7906a95b 196 Gene3D G3DSA:2.60.120.10 15 161 8.6E-27 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS06590 cef625d977e7b186011c16fd7906a95b 196 Pfam PF00027 Cyclic nucleotide-binding domain 35 115 7.1E-14 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS06590 cef625d977e7b186011c16fd7906a95b 196 SMART SM00100 16 138 3.6E-5 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS03020 ee2d96f73e345826b6b8de508c4be01f 241 PANTHER PTHR39181 2 237 7.7E-48 T 13-09-2016 THL1_RS03020 ee2d96f73e345826b6b8de508c4be01f 241 PIRSF PIRSF016557 1 239 1.8E-64 T 13-09-2016 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 UniPathway: UPA00934 THL1_RS03020 ee2d96f73e345826b6b8de508c4be01f 241 SUPERFAMILY SSF89550 1 203 1.33E-12 T 13-09-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 THL1_RS03020 ee2d96f73e345826b6b8de508c4be01f 241 Gene3D G3DSA:3.20.20.140 1 207 8.8E-4 T 13-09-2016 THL1_RS03020 ee2d96f73e345826b6b8de508c4be01f 241 PANTHER PTHR39181:SF1 2 237 7.7E-48 T 13-09-2016 THL1_RS14160 684ef02e127a985e9f3b44f0435b0b09 180 Gene3D G3DSA:3.40.250.10 49 172 1.3E-17 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS14160 684ef02e127a985e9f3b44f0435b0b09 180 Pfam PF00581 Rhodanese-like domain 58 166 6.2E-7 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS14160 684ef02e127a985e9f3b44f0435b0b09 180 SMART SM00450 52 170 0.0024 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS14160 684ef02e127a985e9f3b44f0435b0b09 180 SUPERFAMILY SSF52821 47 179 2.23E-20 T 13-09-2016 IPR001763 Rhodanese-like domain THL1_RS14160 684ef02e127a985e9f3b44f0435b0b09 180 TIGRFAM TIGR03865 PQQ_CXXCW: PQQ-dependent catabolism-associated CXXCW motif protein 18 176 4.3E-67 T 13-09-2016 IPR022376 PQQ-dependent catabolism-associated CXXCW motif THL1_RS02355 fdb7c21a9073430911d582a7d4b9f8fb 229 PANTHER PTHR11751 11 98 7.4E-23 T 13-09-2016 THL1_RS02355 fdb7c21a9073430911d582a7d4b9f8fb 229 SMART SM00895 81 204 4.9E-10 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS02355 fdb7c21a9073430911d582a7d4b9f8fb 229 SUPERFAMILY SSF46785 9 75 1.01E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02355 fdb7c21a9073430911d582a7d4b9f8fb 229 Pfam PF07729 FCD domain 82 203 2.7E-13 T 13-09-2016 IPR011711 GntR, C-terminal THL1_RS02355 fdb7c21a9073430911d582a7d4b9f8fb 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 1.4E-6 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS02355 fdb7c21a9073430911d582a7d4b9f8fb 229 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 1.4E-6 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS02355 fdb7c21a9073430911d582a7d4b9f8fb 229 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 71 1.6E-17 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS02355 fdb7c21a9073430911d582a7d4b9f8fb 229 Gene3D G3DSA:1.20.120.530 74 212 2.4E-22 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS02355 fdb7c21a9073430911d582a7d4b9f8fb 229 Gene3D G3DSA:1.10.10.10 5 72 1.5E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02355 fdb7c21a9073430911d582a7d4b9f8fb 229 SMART SM00345 13 71 2.0E-14 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS02355 fdb7c21a9073430911d582a7d4b9f8fb 229 SUPERFAMILY SSF48008 77 209 2.01E-19 T 13-09-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal THL1_RS03735 92ed745c564fd683a520b54ff582b195 213 PANTHER PTHR35023:SF1 4 213 2.7E-44 T 13-09-2016 THL1_RS03735 92ed745c564fd683a520b54ff582b195 213 PANTHER PTHR35023 4 213 2.7E-44 T 13-09-2016 THL1_RS03735 92ed745c564fd683a520b54ff582b195 213 SUPERFAMILY SSF53300 61 207 5.68E-12 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS03735 92ed745c564fd683a520b54ff582b195 213 Gene3D G3DSA:3.40.50.410 62 172 1.5E-5 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS03735 92ed745c564fd683a520b54ff582b195 213 Pfam PF13519 von Willebrand factor type A domain 61 166 4.8E-7 T 13-09-2016 IPR002035 von Willebrand factor, type A THL1_RS06695 a043b368dce4b601a3e21876b6dd0d34 693 SUPERFAMILY SSF50156 247 321 4.03E-9 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS06695 a043b368dce4b601a3e21876b6dd0d34 693 PANTHER PTHR32060:SF11 1 613 2.6E-269 T 13-09-2016 THL1_RS06695 a043b368dce4b601a3e21876b6dd0d34 693 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 241 321 1.4E-9 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS06695 a043b368dce4b601a3e21876b6dd0d34 693 Gene3D G3DSA:3.90.226.10 341 542 1.3E-60 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS06695 a043b368dce4b601a3e21876b6dd0d34 693 Pfam PF03572 Peptidase family S41 365 538 1.0E-51 T 13-09-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 THL1_RS06695 a043b368dce4b601a3e21876b6dd0d34 693 SMART SM00228 248 325 1.7E-5 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS06695 a043b368dce4b601a3e21876b6dd0d34 693 SUPERFAMILY SSF52096 359 544 1.82E-68 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS06695 a043b368dce4b601a3e21876b6dd0d34 693 SUPERFAMILY SSF52096 184 266 1.82E-68 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS06695 a043b368dce4b601a3e21876b6dd0d34 693 PANTHER PTHR32060 1 613 2.6E-269 T 13-09-2016 THL1_RS06695 a043b368dce4b601a3e21876b6dd0d34 693 Pfam PF11818 C-terminal domain of tail specific protease (DUF3340) 544 684 6.2E-39 T 13-09-2016 IPR020992 Tail specific protease, C-terminal THL1_RS06695 a043b368dce4b601a3e21876b6dd0d34 693 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 203 560 1.0E-94 T 13-09-2016 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 THL1_RS06695 a043b368dce4b601a3e21876b6dd0d34 693 SMART SM00245 331 540 1.6E-55 T 13-09-2016 IPR005151 Tail specific protease GO:0006508|GO:0008236 THL1_RS06695 a043b368dce4b601a3e21876b6dd0d34 693 Gene3D G3DSA:3.30.750.44 202 254 1.4E-4 T 13-09-2016 THL1_RS06695 a043b368dce4b601a3e21876b6dd0d34 693 Gene3D G3DSA:2.30.42.10 255 340 4.8E-16 T 13-09-2016 IPR001478 PDZ domain GO:0005515 THL1_RS02135 88a9e669c3fd7d818f783967885759f8 172 PIRSF PIRSF028103 1 172 6.4E-53 T 13-09-2016 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 THL1_RS02135 88a9e669c3fd7d818f783967885759f8 172 Pfam PF13740 ACT domain 3 66 9.3E-13 T 13-09-2016 THL1_RS02135 88a9e669c3fd7d818f783967885759f8 172 PANTHER PTHR34875:SF1 2 166 4.5E-91 T 13-09-2016 THL1_RS02135 88a9e669c3fd7d818f783967885759f8 172 Gene3D G3DSA:3.30.70.260 86 170 5.2E-23 T 13-09-2016 THL1_RS02135 88a9e669c3fd7d818f783967885759f8 172 SUPERFAMILY SSF55021 2 67 7.16E-14 T 13-09-2016 THL1_RS02135 88a9e669c3fd7d818f783967885759f8 172 SUPERFAMILY SSF55021 87 166 3.15E-16 T 13-09-2016 THL1_RS02135 88a9e669c3fd7d818f783967885759f8 172 PANTHER PTHR34875 2 166 4.5E-91 T 13-09-2016 THL1_RS02135 88a9e669c3fd7d818f783967885759f8 172 Gene3D G3DSA:3.30.70.260 2 75 3.6E-20 T 13-09-2016 THL1_RS08460 1a247967c7dc47cfc4c9bd04b7c66f9d 322 SMART SM00342 233 316 3.1E-19 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS08460 1a247967c7dc47cfc4c9bd04b7c66f9d 322 Pfam PF12833 Helix-turn-helix domain 239 318 1.4E-18 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS08460 1a247967c7dc47cfc4c9bd04b7c66f9d 322 PANTHER PTHR11019:SF58 95 322 8.3E-23 T 13-09-2016 THL1_RS08460 1a247967c7dc47cfc4c9bd04b7c66f9d 322 SUPERFAMILY SSF46689 270 319 2.42E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS08460 1a247967c7dc47cfc4c9bd04b7c66f9d 322 Gene3D G3DSA:1.10.10.60 216 269 1.9E-6 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS08460 1a247967c7dc47cfc4c9bd04b7c66f9d 322 PANTHER PTHR11019 95 322 8.3E-23 T 13-09-2016 THL1_RS08460 1a247967c7dc47cfc4c9bd04b7c66f9d 322 SUPERFAMILY SSF52317 4 197 3.29E-27 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS08460 1a247967c7dc47cfc4c9bd04b7c66f9d 322 Gene3D G3DSA:3.40.50.880 6 214 5.7E-25 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS08460 1a247967c7dc47cfc4c9bd04b7c66f9d 322 Gene3D G3DSA:1.10.10.60 273 319 1.0E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS28440 2bab14dea76d98b045b7590cd90b5085 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 136 3.0E-36 T 13-09-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 THL1_RS28440 2bab14dea76d98b045b7590cd90b5085 156 PANTHER PTHR33445 1 156 3.1E-46 T 13-09-2016 THL1_RS28440 2bab14dea76d98b045b7590cd90b5085 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 155 2.3E-47 T 13-09-2016 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 THL1_RS28440 2bab14dea76d98b045b7590cd90b5085 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 156 12.693 T 13-09-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 THL1_RS28440 2bab14dea76d98b045b7590cd90b5085 156 SUPERFAMILY SSF81573 63 121 3.14E-14 T 13-09-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain THL1_RS28440 2bab14dea76d98b045b7590cd90b5085 156 Gene3D G3DSA:1.20.5.620 63 122 4.7E-22 T 13-09-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain THL1_RS11175 4aefdb51fc9958c2c6924441752fba9a 125 PANTHER PTHR11986:SF72 6 52 1.5E-13 T 13-09-2016 THL1_RS11175 4aefdb51fc9958c2c6924441752fba9a 125 PANTHER PTHR11986 6 52 1.5E-13 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS11175 4aefdb51fc9958c2c6924441752fba9a 125 SUPERFAMILY SSF53720 49 90 3.67E-7 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS11175 4aefdb51fc9958c2c6924441752fba9a 125 Gene3D G3DSA:3.40.605.10 49 86 1.7E-7 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS11175 4aefdb51fc9958c2c6924441752fba9a 125 Pfam PF00171 Aldehyde dehydrogenase family 49 85 6.6E-6 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS20640 22bb7d05e210625cbaf9b2f454e62595 282 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 207 - T 13-09-2016 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS20640 22bb7d05e210625cbaf9b2f454e62595 282 SUPERFAMILY SSF51735 1 183 5.1E-57 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20640 22bb7d05e210625cbaf9b2f454e62595 282 PIRSF PIRSF000105 1 282 3.7E-78 T 13-09-2016 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 THL1_RS20640 22bb7d05e210625cbaf9b2f454e62595 282 PANTHER PTHR23309 1 282 2.5E-133 T 13-09-2016 THL1_RS20640 22bb7d05e210625cbaf9b2f454e62595 282 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 183 2.5E-63 T 13-09-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS20640 22bb7d05e210625cbaf9b2f454e62595 282 Gene3D G3DSA:3.40.50.720 2 186 1.3E-58 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20640 22bb7d05e210625cbaf9b2f454e62595 282 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 1.0E-32 T 13-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS20640 22bb7d05e210625cbaf9b2f454e62595 282 Gene3D G3DSA:1.10.1040.10 187 282 7.4E-34 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS20640 22bb7d05e210625cbaf9b2f454e62595 282 SUPERFAMILY SSF48179 186 282 1.36E-30 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS07860 8789dbd682d7818911ba41a71421f443 302 SUPERFAMILY SSF103481 51 142 2.62E-9 T 13-09-2016 THL1_RS07860 8789dbd682d7818911ba41a71421f443 302 Pfam PF00892 EamA-like transporter family 10 142 1.4E-7 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS07860 8789dbd682d7818911ba41a71421f443 302 Pfam PF00892 EamA-like transporter family 162 297 4.0E-9 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS07860 8789dbd682d7818911ba41a71421f443 302 PANTHER PTHR22911 1 301 3.3E-27 T 13-09-2016 THL1_RS07860 8789dbd682d7818911ba41a71421f443 302 SUPERFAMILY SSF103481 204 300 1.28E-9 T 13-09-2016 THL1_RS02475 0422534409720f72979b7556572058ec 488 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 283 294 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS02475 0422534409720f72979b7556572058ec 488 PANTHER PTHR11699 8 487 1.2E-217 T 13-09-2016 THL1_RS02475 0422534409720f72979b7556572058ec 488 Gene3D G3DSA:3.40.309.10 270 459 2.5E-66 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS02475 0422534409720f72979b7556572058ec 488 Pfam PF00171 Aldehyde dehydrogenase family 21 484 4.4E-162 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS02475 0422534409720f72979b7556572058ec 488 TIGRFAM TIGR03216 OH_muco_semi_DH: 2-hydroxymuconic semialdehyde dehydrogenase 8 487 1.6E-261 T 13-09-2016 IPR017628 2-hydroxymuconic semialdehyde dehydrogenase GO:0016620|GO:0055114 THL1_RS02475 0422534409720f72979b7556572058ec 488 Gene3D G3DSA:3.40.605.10 9 269 8.7E-91 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS02475 0422534409720f72979b7556572058ec 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 255 262 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS02475 0422534409720f72979b7556572058ec 488 SUPERFAMILY SSF53720 6 487 2.62E-161 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS02475 0422534409720f72979b7556572058ec 488 PANTHER PTHR11699:SF213 8 487 1.2E-217 T 13-09-2016 THL1_RS00825 f92be532cb2af4d33810f4a65413be23 222 Gene3D G3DSA:1.10.3720.10 11 216 4.2E-50 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00825 f92be532cb2af4d33810f4a65413be23 222 PANTHER PTHR30614:SF18 6 221 3.9E-113 T 13-09-2016 THL1_RS00825 f92be532cb2af4d33810f4a65413be23 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 216 1.8E-23 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00825 f92be532cb2af4d33810f4a65413be23 222 PANTHER PTHR30614 6 221 3.9E-113 T 13-09-2016 THL1_RS00825 f92be532cb2af4d33810f4a65413be23 222 SUPERFAMILY SSF161098 14 204 6.15E-47 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00825 f92be532cb2af4d33810f4a65413be23 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 110 4.8E-34 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS23970 66d927b31479dadfbf860b9b97a9372b 276 PANTHER PTHR18895 11 274 2.0E-107 T 13-09-2016 THL1_RS23970 66d927b31479dadfbf860b9b97a9372b 276 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 18 274 7.5E-77 T 13-09-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 THL1_RS23970 66d927b31479dadfbf860b9b97a9372b 276 Gene3D G3DSA:1.10.8.10 10 83 2.8E-25 T 13-09-2016 THL1_RS23970 66d927b31479dadfbf860b9b97a9372b 276 SUPERFAMILY SSF53335 12 272 3.11E-57 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS23970 66d927b31479dadfbf860b9b97a9372b 276 PANTHER PTHR18895:SF64 11 274 2.0E-107 T 13-09-2016 THL1_RS23970 66d927b31479dadfbf860b9b97a9372b 276 Pfam PF13847 Methyltransferase domain 110 239 1.2E-16 T 13-09-2016 IPR025714 Methyltransferase domain THL1_RS23970 66d927b31479dadfbf860b9b97a9372b 276 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 22 270 5.1E-90 T 13-09-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 THL1_RS23970 66d927b31479dadfbf860b9b97a9372b 276 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 179 185 - T 13-09-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THL1_RS23970 66d927b31479dadfbf860b9b97a9372b 276 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 2 274 45.451 T 13-09-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 THL1_RS23970 66d927b31479dadfbf860b9b97a9372b 276 Gene3D G3DSA:3.40.50.150 85 274 5.5E-69 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS24070 780e1d49bfb9349c3bd314ca19d5fc3a 214 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 13-09-2016 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS24070 780e1d49bfb9349c3bd314ca19d5fc3a 214 SUPERFAMILY SSF53056 1 203 1.31E-73 T 13-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS24070 780e1d49bfb9349c3bd314ca19d5fc3a 214 PANTHER PTHR11002:SF20 1 208 1.6E-125 T 13-09-2016 THL1_RS24070 780e1d49bfb9349c3bd314ca19d5fc3a 214 Pfam PF00484 Carbonic anhydrase 38 187 1.3E-49 T 13-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS24070 780e1d49bfb9349c3bd314ca19d5fc3a 214 PANTHER PTHR11002 1 208 1.6E-125 T 13-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS24070 780e1d49bfb9349c3bd314ca19d5fc3a 214 Gene3D G3DSA:3.40.1050.10 2 202 8.2E-75 T 13-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS24070 780e1d49bfb9349c3bd314ca19d5fc3a 214 SMART SM00947 30 193 2.7E-64 T 13-09-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THL1_RS02425 e59d8cac7591cbbf7fe70a185bc3995b 264 SUPERFAMILY SSF53850 1 256 1.81E-65 T 13-09-2016 THL1_RS02425 e59d8cac7591cbbf7fe70a185bc3995b 264 Gene3D G3DSA:3.40.190.10 30 110 2.6E-38 T 13-09-2016 THL1_RS02425 e59d8cac7591cbbf7fe70a185bc3995b 264 Gene3D G3DSA:3.40.190.10 217 256 2.6E-38 T 13-09-2016 THL1_RS02425 e59d8cac7591cbbf7fe70a185bc3995b 264 Gene3D G3DSA:3.40.190.10 111 216 8.9E-16 T 13-09-2016 THL1_RS02425 e59d8cac7591cbbf7fe70a185bc3995b 264 SMART SM00062 33 257 3.4E-56 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS02425 e59d8cac7591cbbf7fe70a185bc3995b 264 SMART SM00079 33 256 8.1E-5 T 13-09-2016 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 THL1_RS02425 e59d8cac7591cbbf7fe70a185bc3995b 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 255 3.1E-56 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS02425 e59d8cac7591cbbf7fe70a185bc3995b 264 PANTHER PTHR18966 22 259 6.3E-79 T 13-09-2016 THL1_RS02425 e59d8cac7591cbbf7fe70a185bc3995b 264 PANTHER PTHR18966:SF152 22 259 6.3E-79 T 13-09-2016 THL1_RS21570 c9507e224dd96a05703a75eb405e5481 333 Pfam PF00691 OmpA family 179 274 1.2E-15 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS21570 c9507e224dd96a05703a75eb405e5481 333 Gene3D G3DSA:3.30.1330.60 176 280 2.3E-25 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS21570 c9507e224dd96a05703a75eb405e5481 333 SUPERFAMILY SSF103088 149 279 4.32E-28 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS21570 c9507e224dd96a05703a75eb405e5481 333 PANTHER PTHR30128 177 298 3.3E-27 T 13-09-2016 THL1_RS21570 c9507e224dd96a05703a75eb405e5481 333 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 243 262 2.1E-17 T 13-09-2016 THL1_RS21570 c9507e224dd96a05703a75eb405e5481 333 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 263 283 2.1E-17 T 13-09-2016 THL1_RS21570 c9507e224dd96a05703a75eb405e5481 333 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 39 57 2.1E-17 T 13-09-2016 THL1_RS21570 c9507e224dd96a05703a75eb405e5481 333 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 140 159 2.1E-17 T 13-09-2016 THL1_RS21570 c9507e224dd96a05703a75eb405e5481 333 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 225 242 2.1E-17 T 13-09-2016 THL1_RS21570 c9507e224dd96a05703a75eb405e5481 333 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 77 95 2.1E-17 T 13-09-2016 THL1_RS21570 c9507e224dd96a05703a75eb405e5481 333 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 196 222 2.1E-17 T 13-09-2016 THL1_RS05360 2f9b2032994e208b6ca6b4f729aeac7f 102 Gene3D G3DSA:3.30.160.100 1 92 8.6E-38 T 13-09-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 THL1_RS05360 2f9b2032994e208b6ca6b4f729aeac7f 102 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 92 1.5E-28 T 13-09-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 THL1_RS05360 2f9b2032994e208b6ca6b4f729aeac7f 102 PANTHER PTHR33231 1 95 1.5E-40 T 13-09-2016 THL1_RS05360 2f9b2032994e208b6ca6b4f729aeac7f 102 SUPERFAMILY SSF69754 1 97 4.71E-36 T 13-09-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 THL1_RS05360 2f9b2032994e208b6ca6b4f729aeac7f 102 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 98 7.2E-37 T 13-09-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 THL1_RS10575 1b2c55eb79864bf1a0b89f6b072841e3 644 Gene3D G3DSA:1.25.20.10 28 386 4.7E-103 T 13-09-2016 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 THL1_RS10575 1b2c55eb79864bf1a0b89f6b072841e3 644 Gene3D G3DSA:1.10.530.10 475 636 6.3E-50 T 13-09-2016 THL1_RS10575 1b2c55eb79864bf1a0b89f6b072841e3 644 SUPERFAMILY SSF53955 480 638 1.19E-46 T 13-09-2016 IPR023346 Lysozyme-like domain THL1_RS10575 1b2c55eb79864bf1a0b89f6b072841e3 644 Pfam PF14718 Soluble lytic murein transglycosylase L domain 406 472 3.9E-17 T 13-09-2016 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 THL1_RS10575 1b2c55eb79864bf1a0b89f6b072841e3 644 Gene3D G3DSA:1.10.1240.20 404 472 5.7E-18 T 13-09-2016 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 THL1_RS10575 1b2c55eb79864bf1a0b89f6b072841e3 644 Pfam PF01464 Transglycosylase SLT domain 487 597 6.6E-29 T 13-09-2016 IPR008258 Transglycosylase SLT domain 1 THL1_RS10575 1b2c55eb79864bf1a0b89f6b072841e3 644 PANTHER PTHR21666 463 623 6.3E-48 T 13-09-2016 THL1_RS10575 1b2c55eb79864bf1a0b89f6b072841e3 644 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 501 529 - T 13-09-2016 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 THL1_RS10575 1b2c55eb79864bf1a0b89f6b072841e3 644 SUPERFAMILY SSF48435 28 477 7.19E-127 T 13-09-2016 IPR016026 Lytic transglycosylase, superhelical U-shaped and linker domain GO:0004553|GO:0042597 THL1_RS07355 c50f649787c8e17df25ce50ef7e15fdf 367 Gene3D G3DSA:3.40.190.10 149 315 9.3E-67 T 13-09-2016 THL1_RS07355 c50f649787c8e17df25ce50ef7e15fdf 367 PANTHER PTHR30222:SF11 22 367 1.1E-172 T 13-09-2016 THL1_RS07355 c50f649787c8e17df25ce50ef7e15fdf 367 Pfam PF13416 Bacterial extracellular solute-binding protein 45 331 6.1E-30 T 13-09-2016 THL1_RS07355 c50f649787c8e17df25ce50ef7e15fdf 367 PIRSF PIRSF019574 5 367 1.4E-125 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS07355 c50f649787c8e17df25ce50ef7e15fdf 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 125 141 6.8E-63 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS07355 c50f649787c8e17df25ce50ef7e15fdf 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 33 49 6.8E-63 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS07355 c50f649787c8e17df25ce50ef7e15fdf 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 92 105 6.8E-63 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS07355 c50f649787c8e17df25ce50ef7e15fdf 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 49 70 6.8E-63 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS07355 c50f649787c8e17df25ce50ef7e15fdf 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 311 337 6.8E-63 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS07355 c50f649787c8e17df25ce50ef7e15fdf 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 156 170 6.8E-63 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS07355 c50f649787c8e17df25ce50ef7e15fdf 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 76 90 6.8E-63 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS07355 c50f649787c8e17df25ce50ef7e15fdf 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 179 198 6.8E-63 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS07355 c50f649787c8e17df25ce50ef7e15fdf 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 216 235 6.8E-63 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS07355 c50f649787c8e17df25ce50ef7e15fdf 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 266 285 6.8E-63 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS07355 c50f649787c8e17df25ce50ef7e15fdf 367 PANTHER PTHR30222 22 367 1.1E-172 T 13-09-2016 THL1_RS07355 c50f649787c8e17df25ce50ef7e15fdf 367 SUPERFAMILY SSF53850 29 366 1.71E-93 T 13-09-2016 THL1_RS07355 c50f649787c8e17df25ce50ef7e15fdf 367 Gene3D G3DSA:3.40.190.10 30 148 2.0E-22 T 13-09-2016 THL1_RS10815 04a137ae4cf75cf1454bec75233ba524 180 PANTHER PTHR23044:SF5 3 178 3.5E-65 T 13-09-2016 THL1_RS10815 04a137ae4cf75cf1454bec75233ba524 180 Pfam PF00929 Exonuclease 5 174 2.4E-18 T 13-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III THL1_RS10815 04a137ae4cf75cf1454bec75233ba524 180 Gene3D G3DSA:3.30.420.10 3 175 6.4E-51 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS10815 04a137ae4cf75cf1454bec75233ba524 180 SMART SM00479 3 180 5.8E-7 T 13-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III THL1_RS10815 04a137ae4cf75cf1454bec75233ba524 180 SUPERFAMILY SSF53098 3 177 3.67E-31 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS10815 04a137ae4cf75cf1454bec75233ba524 180 PANTHER PTHR23044 3 178 3.5E-65 T 13-09-2016 THL1_RS02685 0c4d825d2e73c2e43da07f830a8d271d 495 SUPERFAMILY SSF56322 14 485 6.8E-160 T 13-09-2016 IPR005801 ADC synthase GO:0009058 THL1_RS02685 0c4d825d2e73c2e43da07f830a8d271d 495 Gene3D G3DSA:3.60.120.10 12 490 3.1E-178 T 13-09-2016 IPR005801 ADC synthase GO:0009058 THL1_RS02685 0c4d825d2e73c2e43da07f830a8d271d 495 PANTHER PTHR11236:SF9 1 489 3.5E-238 T 13-09-2016 THL1_RS02685 0c4d825d2e73c2e43da07f830a8d271d 495 Pfam PF00425 chorismate binding enzyme 223 476 2.8E-99 T 13-09-2016 IPR015890 Chorismate-utilising enzyme, C-terminal THL1_RS02685 0c4d825d2e73c2e43da07f830a8d271d 495 PANTHER PTHR11236 1 489 3.5E-238 T 13-09-2016 THL1_RS02685 0c4d825d2e73c2e43da07f830a8d271d 495 Pfam PF04715 Anthranilate synthase component I, N terminal region 28 168 3.4E-35 T 13-09-2016 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 THL1_RS02685 0c4d825d2e73c2e43da07f830a8d271d 495 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 26 484 4.2E-172 T 13-09-2016 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 THL1_RS02685 0c4d825d2e73c2e43da07f830a8d271d 495 PRINTS PR00095 Anthranilate synthase component I signature 324 337 1.1E-25 T 13-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 THL1_RS02685 0c4d825d2e73c2e43da07f830a8d271d 495 PRINTS PR00095 Anthranilate synthase component I signature 433 447 1.1E-25 T 13-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 THL1_RS02685 0c4d825d2e73c2e43da07f830a8d271d 495 PRINTS PR00095 Anthranilate synthase component I signature 418 432 1.1E-25 T 13-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 THL1_RS02685 0c4d825d2e73c2e43da07f830a8d271d 495 PRINTS PR00095 Anthranilate synthase component I signature 338 351 1.1E-25 T 13-09-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 THL1_RS00380 fe362f6f3de01c360fe13fa5876864b5 201 PIRSF PIRSF000005 1 201 3.8E-63 T 13-09-2016 IPR024167 Cytochrome c4 GO:0005506|GO:0009055|GO:0020037|GO:0042597 THL1_RS00380 fe362f6f3de01c360fe13fa5876864b5 201 Pfam PF00034 Cytochrome c 111 199 5.2E-8 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS00380 fe362f6f3de01c360fe13fa5876864b5 201 Pfam PF00034 Cytochrome c 31 100 2.7E-8 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS00380 fe362f6f3de01c360fe13fa5876864b5 201 PANTHER PTHR33751 1 201 6.5E-65 T 13-09-2016 THL1_RS00380 fe362f6f3de01c360fe13fa5876864b5 201 Gene3D G3DSA:1.10.760.10 21 101 5.0E-27 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS00380 fe362f6f3de01c360fe13fa5876864b5 201 SUPERFAMILY SSF46626 104 200 3.55E-22 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS00380 fe362f6f3de01c360fe13fa5876864b5 201 Gene3D G3DSA:1.10.760.10 108 201 1.2E-29 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS00380 fe362f6f3de01c360fe13fa5876864b5 201 PANTHER PTHR33751:SF3 1 201 6.5E-65 T 13-09-2016 THL1_RS00380 fe362f6f3de01c360fe13fa5876864b5 201 SUPERFAMILY SSF46626 14 99 1.48E-21 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS19475 2e9ede1676701e40ea476e7ff6afa553 262 PANTHER PTHR13696:SF69 1 253 2.7E-145 T 13-09-2016 THL1_RS19475 2e9ede1676701e40ea476e7ff6afa553 262 SUPERFAMILY SSF52540 1 255 3.13E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS19475 2e9ede1676701e40ea476e7ff6afa553 262 Pfam PF13614 AAA domain 1 179 1.1E-41 T 13-09-2016 IPR025669 AAA domain THL1_RS19475 2e9ede1676701e40ea476e7ff6afa553 262 Gene3D G3DSA:3.40.50.300 1 255 9.1E-56 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS19475 2e9ede1676701e40ea476e7ff6afa553 262 PANTHER PTHR13696 1 253 2.7E-145 T 13-09-2016 THL1_RS00640 8e1fdbdf83f7704d22e0939bfe8a9116 246 Gene3D G3DSA:3.40.50.720 3 232 3.5E-46 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS00640 8e1fdbdf83f7704d22e0939bfe8a9116 246 Pfam PF00106 short chain dehydrogenase 9 199 1.2E-34 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS00640 8e1fdbdf83f7704d22e0939bfe8a9116 246 PANTHER PTHR24322 13 141 3.7E-57 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS00640 8e1fdbdf83f7704d22e0939bfe8a9116 246 PANTHER PTHR24322 157 189 3.7E-57 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS00640 8e1fdbdf83f7704d22e0939bfe8a9116 246 SUPERFAMILY SSF51735 5 236 1.44E-46 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS00640 8e1fdbdf83f7704d22e0939bfe8a9116 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.7E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS00640 8e1fdbdf83f7704d22e0939bfe8a9116 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.7E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS00640 8e1fdbdf83f7704d22e0939bfe8a9116 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.7E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS00640 8e1fdbdf83f7704d22e0939bfe8a9116 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.7E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS00640 8e1fdbdf83f7704d22e0939bfe8a9116 246 PANTHER PTHR24322:SF360 13 141 3.7E-57 T 13-09-2016 THL1_RS00640 8e1fdbdf83f7704d22e0939bfe8a9116 246 PANTHER PTHR24322:SF360 157 189 3.7E-57 T 13-09-2016 THL1_RS09315 412a4bb292c49afba657836c686177d8 297 SUPERFAMILY SSF53850 93 294 1.55E-32 T 13-09-2016 THL1_RS09315 412a4bb292c49afba657836c686177d8 297 Gene3D G3DSA:1.10.10.10 5 84 8.2E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09315 412a4bb292c49afba657836c686177d8 297 Gene3D G3DSA:3.40.190.10 93 199 1.1E-17 T 13-09-2016 THL1_RS09315 412a4bb292c49afba657836c686177d8 297 SUPERFAMILY SSF46785 3 85 6.05E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS09315 412a4bb292c49afba657836c686177d8 297 Pfam PF03466 LysR substrate binding domain 92 294 3.0E-34 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS09315 412a4bb292c49afba657836c686177d8 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 3.0E-14 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS09315 412a4bb292c49afba657836c686177d8 297 PANTHER PTHR30126 6 291 5.7E-150 T 13-09-2016 THL1_RS09315 412a4bb292c49afba657836c686177d8 297 PANTHER PTHR30126:SF16 6 291 5.7E-150 T 13-09-2016 THL1_RS27765 3e96ecb5372966b42b7118701d6b688f 117 PANTHER PTHR11803 11 117 3.7E-33 T 13-09-2016 IPR006175 YjgF/YER057c/UK114 family THL1_RS27765 3e96ecb5372966b42b7118701d6b688f 117 Pfam PF01042 Endoribonuclease L-PSP 4 115 8.2E-27 T 13-09-2016 IPR006175 YjgF/YER057c/UK114 family THL1_RS27765 3e96ecb5372966b42b7118701d6b688f 117 Gene3D G3DSA:3.30.1330.40 6 116 8.4E-27 T 13-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THL1_RS27765 3e96ecb5372966b42b7118701d6b688f 117 SUPERFAMILY SSF55298 3 117 6.91E-31 T 13-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THL1_RS13700 cad558fd107cfbbd73474755f6419dbe 267 Gene3D G3DSA:3.90.850.10 2 267 5.6E-88 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS13700 cad558fd107cfbbd73474755f6419dbe 267 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 103 266 1.3E-10 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS13700 cad558fd107cfbbd73474755f6419dbe 267 TIGRFAM TIGR02312 HpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 1 267 1.7E-140 T 13-09-2016 IPR012690 2-oxo-hepta-3-ene-1,7-dioic acid hydratase GO:0019439 UniPathway: UPA00208 THL1_RS13700 cad558fd107cfbbd73474755f6419dbe 267 PANTHER PTHR30143 1 267 6.7E-97 T 13-09-2016 THL1_RS13700 cad558fd107cfbbd73474755f6419dbe 267 SUPERFAMILY SSF56529 3 267 6.8E-79 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS07100 a68737a2e63db45d013fa7d7be7d2721 408 Pfam PF13657 HipA N-terminal domain 18 100 1.2E-6 T 13-09-2016 IPR017508 HipA, N-terminal subdomain 1 THL1_RS07100 a68737a2e63db45d013fa7d7be7d2721 408 Pfam PF07805 HipA-like N-terminal domain 179 233 2.6E-9 T 13-09-2016 IPR012894 HipA, N-terminal subdomain 2 THL1_RS07100 a68737a2e63db45d013fa7d7be7d2721 408 PANTHER PTHR37419:SF2 64 327 2.9E-16 T 13-09-2016 THL1_RS07100 a68737a2e63db45d013fa7d7be7d2721 408 PANTHER PTHR37419 64 327 2.9E-16 T 13-09-2016 THL1_RS07100 a68737a2e63db45d013fa7d7be7d2721 408 Pfam PF07804 HipA-like C-terminal domain 244 378 6.3E-28 T 13-09-2016 IPR012893 HipA-like, C-terminal THL1_RS26150 4a418a684c9488a645d93bdf40d9d07d 251 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 23 223 2.3E-52 T 13-09-2016 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 THL1_RS26150 4a418a684c9488a645d93bdf40d9d07d 251 PIRSF PIRSF026326 3 234 3.4E-68 T 13-09-2016 IPR027023 Putative lipopolysaccharide kinase InaA THL1_RS26150 4a418a684c9488a645d93bdf40d9d07d 251 SUPERFAMILY SSF56112 39 238 9.78E-13 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS00270 55dc467a9ba45ae70004fc6802166b32 67 Pfam PF11137 Protein of unknown function (DUF2909) 2 60 7.2E-21 T 13-09-2016 IPR021313 Protein of unknown function DUF2909 THL1_RS09610 d7f45ef0357af18837cad9da4a4ee0eb 328 PANTHER PTHR35007:SF1 7 328 2.1E-46 T 13-09-2016 THL1_RS09610 d7f45ef0357af18837cad9da4a4ee0eb 328 Pfam PF00482 Type II secretion system (T2SS), protein F 161 285 2.2E-23 T 13-09-2016 IPR018076 Type II secretion system F domain THL1_RS09610 d7f45ef0357af18837cad9da4a4ee0eb 328 PANTHER PTHR35007 7 328 2.1E-46 T 13-09-2016 THL1_RS08220 326c5294962b3ee794dfe8cd8b951e4d 499 PANTHER PTHR22773 2 491 9.3E-150 T 13-09-2016 THL1_RS08220 326c5294962b3ee794dfe8cd8b951e4d 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 160 184 3.0E-10 T 13-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 THL1_RS08220 326c5294962b3ee794dfe8cd8b951e4d 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 130 149 3.0E-10 T 13-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 THL1_RS08220 326c5294962b3ee794dfe8cd8b951e4d 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 378 404 3.0E-10 T 13-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 THL1_RS08220 326c5294962b3ee794dfe8cd8b951e4d 499 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 233 257 3.0E-10 T 13-09-2016 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 THL1_RS08220 326c5294962b3ee794dfe8cd8b951e4d 499 PANTHER PTHR22773:SF49 2 491 9.3E-150 T 13-09-2016 THL1_RS08220 326c5294962b3ee794dfe8cd8b951e4d 499 Pfam PF00361 Proton-conducting membrane transporter 125 403 9.5E-42 T 13-09-2016 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: REACT_6305 THL1_RS25645 24a28536286de47e0df343b644510dae 204 Hamap MF_01389 Urease accessory protein UreG [ureG]. 4 202 47.846 T 13-09-2016 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 THL1_RS25645 24a28536286de47e0df343b644510dae 204 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 8 178 6.8E-36 T 13-09-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain THL1_RS25645 24a28536286de47e0df343b644510dae 204 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 6 201 4.3E-105 T 13-09-2016 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 THL1_RS25645 24a28536286de47e0df343b644510dae 204 PANTHER PTHR31715 1 204 1.1E-130 T 13-09-2016 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 THL1_RS25645 24a28536286de47e0df343b644510dae 204 SUPERFAMILY SSF52540 3 197 1.07E-35 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25645 24a28536286de47e0df343b644510dae 204 Gene3D G3DSA:3.40.50.300 5 197 9.3E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25645 24a28536286de47e0df343b644510dae 204 PIRSF PIRSF005624 2 204 2.9E-46 T 13-09-2016 THL1_RS11905 39c228329655ffc10a59162023b06065 236 Gene3D G3DSA:3.90.1550.10 9 211 1.3E-45 T 13-09-2016 THL1_RS11905 39c228329655ffc10a59162023b06065 236 SUPERFAMILY SSF55681 9 212 1.66E-41 T 13-09-2016 THL1_RS26670 4ac3087ed40a41b80d8f526693b20b2d 205 Pfam PF13511 Domain of unknown function (DUF4124) 7 59 6.7E-12 T 13-09-2016 IPR025392 Domain of unknown function DUF4124 THL1_RS26670 4ac3087ed40a41b80d8f526693b20b2d 205 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 74 153 6.9E-6 T 13-09-2016 IPR009647 Penicillin-binding, C-terminal KEGG: 00230+2.4.2.-|KEGG: 00514+2.4.2.-|UniPathway: UPA00219 THL1_RS26515 79f8bd67c3aa2dd19c386bf794b47af4 510 Gene3D G3DSA:1.20.200.10 200 504 1.3E-112 T 13-09-2016 THL1_RS26515 79f8bd67c3aa2dd19c386bf794b47af4 510 PANTHER PTHR10362:SF7 4 506 8.7E-197 T 13-09-2016 THL1_RS26515 79f8bd67c3aa2dd19c386bf794b47af4 510 SUPERFAMILY SSF48557 7 502 2.9E-162 T 13-09-2016 IPR008948 L-Aspartase-like GO:0003824 THL1_RS26515 79f8bd67c3aa2dd19c386bf794b47af4 510 Gene3D G3DSA:1.10.275.10 7 197 6.6E-56 T 13-09-2016 IPR024083 Fumarase/histidase, N-terminal THL1_RS26515 79f8bd67c3aa2dd19c386bf794b47af4 510 PANTHER PTHR10362 4 506 8.7E-197 T 13-09-2016 THL1_RS26515 79f8bd67c3aa2dd19c386bf794b47af4 510 Pfam PF00221 Aromatic amino acid lyase 14 471 6.4E-160 T 13-09-2016 IPR001106 Aromatic amino acid lyase THL1_RS09550 3a838c785aa38f86e0a21388e2c2dd3e 285 SMART SM00342 177 260 4.6E-32 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS09550 3a838c785aa38f86e0a21388e2c2dd3e 285 Gene3D G3DSA:1.10.10.60 158 214 1.5E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS09550 3a838c785aa38f86e0a21388e2c2dd3e 285 SUPERFAMILY SSF46689 160 210 1.43E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS09550 3a838c785aa38f86e0a21388e2c2dd3e 285 Pfam PF12833 Helix-turn-helix domain 183 261 3.7E-23 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS09550 3a838c785aa38f86e0a21388e2c2dd3e 285 Gene3D G3DSA:1.10.10.60 215 265 1.7E-19 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS09550 3a838c785aa38f86e0a21388e2c2dd3e 285 SUPERFAMILY SSF46689 214 264 2.6E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS09550 3a838c785aa38f86e0a21388e2c2dd3e 285 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 214 256 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS09550 3a838c785aa38f86e0a21388e2c2dd3e 285 Gene3D G3DSA:3.40.50.2300 49 114 1.1E-7 T 13-09-2016 THL1_RS09550 3a838c785aa38f86e0a21388e2c2dd3e 285 PANTHER PTHR11019:SF65 158 268 4.8E-34 T 13-09-2016 THL1_RS09550 3a838c785aa38f86e0a21388e2c2dd3e 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 229 244 3.2E-7 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS09550 3a838c785aa38f86e0a21388e2c2dd3e 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 244 260 3.2E-7 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS09550 3a838c785aa38f86e0a21388e2c2dd3e 285 Pfam PF00072 Response regulator receiver domain 49 111 4.6E-7 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS09550 3a838c785aa38f86e0a21388e2c2dd3e 285 PANTHER PTHR11019 158 268 4.8E-34 T 13-09-2016 THL1_RS09550 3a838c785aa38f86e0a21388e2c2dd3e 285 SUPERFAMILY SSF52172 46 128 2.13E-10 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS17530 24165064f5f2b04aef104569aa916465 251 PIRSF PIRSF003073 1 250 3.4E-76 T 13-09-2016 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein THL1_RS17530 24165064f5f2b04aef104569aa916465 251 SUPERFAMILY SSF52540 64 243 1.68E-28 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17530 24165064f5f2b04aef104569aa916465 251 SMART SM00382 98 231 4.6E-7 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS17530 24165064f5f2b04aef104569aa916465 251 Gene3D G3DSA:3.40.50.300 53 229 2.2E-28 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17530 24165064f5f2b04aef104569aa916465 251 PANTHER PTHR30050:SF6 8 243 3.6E-82 T 13-09-2016 THL1_RS17530 24165064f5f2b04aef104569aa916465 251 Pfam PF01695 IstB-like ATP binding protein 53 229 3.8E-66 T 13-09-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 THL1_RS17530 24165064f5f2b04aef104569aa916465 251 Pfam PF08483 IstB-like ATP binding N-terminal 24 52 1.4E-14 T 13-09-2016 IPR013690 IstB-like ATP binding N-terminal THL1_RS17530 24165064f5f2b04aef104569aa916465 251 PANTHER PTHR30050 8 243 3.6E-82 T 13-09-2016 THL1_RS07200 4b184387685088998bd12eca610c2f93 121 SUPERFAMILY SSF52172 3 120 3.7E-35 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS07200 4b184387685088998bd12eca610c2f93 121 Gene3D G3DSA:3.40.50.2300 2 120 2.1E-35 T 13-09-2016 THL1_RS07200 4b184387685088998bd12eca610c2f93 121 PANTHER PTHR26402 3 120 1.5E-48 T 13-09-2016 THL1_RS07200 4b184387685088998bd12eca610c2f93 121 PANTHER PTHR26402:SF586 3 120 1.5E-48 T 13-09-2016 THL1_RS07200 4b184387685088998bd12eca610c2f93 121 SMART SM00448 3 116 5.7E-36 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS07200 4b184387685088998bd12eca610c2f93 121 Pfam PF00072 Response regulator receiver domain 5 115 1.7E-27 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS11310 3038c3dbf4b15e4784bb2d387e8f75be 383 SUPERFAMILY SSF53850 35 357 1.99E-57 T 13-09-2016 THL1_RS11310 3038c3dbf4b15e4784bb2d387e8f75be 383 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 138 154 4.1E-8 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS11310 3038c3dbf4b15e4784bb2d387e8f75be 383 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 64 85 4.1E-8 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS11310 3038c3dbf4b15e4784bb2d387e8f75be 383 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 163 177 4.1E-8 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS11310 3038c3dbf4b15e4784bb2d387e8f75be 383 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 278 297 4.1E-8 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS11310 3038c3dbf4b15e4784bb2d387e8f75be 383 Gene3D G3DSA:3.40.190.10 149 301 2.6E-30 T 13-09-2016 THL1_RS11310 3038c3dbf4b15e4784bb2d387e8f75be 383 Pfam PF13416 Bacterial extracellular solute-binding protein 58 328 1.5E-27 T 13-09-2016 THL1_RS11310 3038c3dbf4b15e4784bb2d387e8f75be 383 Gene3D G3DSA:3.40.190.10 35 147 2.8E-27 T 13-09-2016 THL1_RS11310 3038c3dbf4b15e4784bb2d387e8f75be 383 Gene3D G3DSA:3.40.190.10 302 329 2.8E-27 T 13-09-2016 THL1_RS11310 3038c3dbf4b15e4784bb2d387e8f75be 383 PANTHER PTHR30222 16 327 1.3E-69 T 13-09-2016 THL1_RS11310 3038c3dbf4b15e4784bb2d387e8f75be 383 PANTHER PTHR30222:SF5 16 327 1.3E-69 T 13-09-2016 THL1_RS20630 5c9c6576cb172a949dbd149880800e7a 326 PANTHER PTHR35604 3 324 1.1E-184 T 13-09-2016 THL1_RS20630 5c9c6576cb172a949dbd149880800e7a 326 PANTHER PTHR35604:SF2 3 324 1.1E-184 T 13-09-2016 THL1_RS20630 5c9c6576cb172a949dbd149880800e7a 326 Pfam PF01609 Transposase DDE domain 134 310 7.5E-33 T 13-09-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THL1_RS20630 5c9c6576cb172a949dbd149880800e7a 326 Pfam PF05598 Transposase domain (DUF772) 50 115 3.0E-20 T 13-09-2016 IPR008490 Transposase InsH, N-terminal THL1_RS20960 a617f643ce426b8896dd0c670e7c24e9 193 Gene3D G3DSA:1.10.357.10 54 186 1.3E-16 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS20960 a617f643ce426b8896dd0c670e7c24e9 193 Gene3D G3DSA:1.10.10.60 4 53 9.3E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS20960 a617f643ce426b8896dd0c670e7c24e9 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 53 4.8E-10 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20960 a617f643ce426b8896dd0c670e7c24e9 193 PANTHER PTHR30055 5 157 5.3E-18 T 13-09-2016 THL1_RS20960 a617f643ce426b8896dd0c670e7c24e9 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 6.7E-5 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20960 a617f643ce426b8896dd0c670e7c24e9 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 6.7E-5 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS20960 a617f643ce426b8896dd0c670e7c24e9 193 SUPERFAMILY SSF46689 4 66 3.4E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS20960 a617f643ce426b8896dd0c670e7c24e9 193 SUPERFAMILY SSF48498 73 158 4.14E-9 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS09845 a89302f3d35098739d03695c475a7d9a 378 PANTHER PTHR12526 24 375 6.3E-51 T 13-09-2016 THL1_RS09845 a89302f3d35098739d03695c475a7d9a 378 Pfam PF00534 Glycosyl transferases group 1 188 354 1.7E-34 T 13-09-2016 IPR001296 Glycosyl transferase, family 1 THL1_RS09845 a89302f3d35098739d03695c475a7d9a 378 SUPERFAMILY SSF53756 18 374 1.77E-74 T 13-09-2016 THL1_RS09845 a89302f3d35098739d03695c475a7d9a 378 Gene3D G3DSA:3.40.50.2000 175 354 1.7E-33 T 13-09-2016 THL1_RS09845 a89302f3d35098739d03695c475a7d9a 378 Pfam PF13579 Glycosyl transferase 4-like domain 25 168 1.7E-12 T 13-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain THL1_RS08225 50400137fb097de366beef040361c3ac 166 PANTHER PTHR34584:SF1 4 165 6.5E-44 T 13-09-2016 THL1_RS08225 50400137fb097de366beef040361c3ac 166 PIRSF PIRSF019239 2 165 1.7E-38 T 13-09-2016 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 THL1_RS08225 50400137fb097de366beef040361c3ac 166 Pfam PF01899 Na+/H+ ion antiporter subunit 13 160 6.8E-40 T 13-09-2016 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 THL1_RS08225 50400137fb097de366beef040361c3ac 166 PANTHER PTHR34584 4 165 6.5E-44 T 13-09-2016 THL1_RS15785 78394eb2c4baab67d4428511ce66f958 130 Gene3D G3DSA:3.90.1590.10 2 120 1.6E-32 T 13-09-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801|UniPathway: UPA00562 THL1_RS15785 78394eb2c4baab67d4428511ce66f958 130 PANTHER PTHR33337:SF10 1 119 2.8E-37 T 13-09-2016 THL1_RS15785 78394eb2c4baab67d4428511ce66f958 130 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 26 102 1.3E-16 T 13-09-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801|UniPathway: UPA00562 THL1_RS15785 78394eb2c4baab67d4428511ce66f958 130 SUPERFAMILY SSF51316 3 123 2.09E-35 T 13-09-2016 IPR011057 Mss4-like THL1_RS15785 78394eb2c4baab67d4428511ce66f958 130 PANTHER PTHR33337 1 119 2.8E-37 T 13-09-2016 THL1_RS07755 c21e138f99cd7e835455552365b561df 399 PANTHER PTHR23502 5 386 1.5E-58 T 13-09-2016 THL1_RS07755 c21e138f99cd7e835455552365b561df 399 SUPERFAMILY SSF103473 5 391 2.09E-45 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS07755 c21e138f99cd7e835455552365b561df 399 ProSitePatterns PS00216 Sugar transport proteins signature 1. 61 77 - T 13-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 THL1_RS07755 c21e138f99cd7e835455552365b561df 399 PANTHER PTHR23502:SF19 5 386 1.5E-58 T 13-09-2016 THL1_RS07755 c21e138f99cd7e835455552365b561df 399 Gene3D G3DSA:1.20.1250.20 3 184 1.4E-20 T 13-09-2016 THL1_RS07755 c21e138f99cd7e835455552365b561df 399 Pfam PF07690 Major Facilitator Superfamily 17 351 1.2E-30 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS07755 c21e138f99cd7e835455552365b561df 399 Gene3D G3DSA:1.20.1250.20 205 391 7.8E-9 T 13-09-2016 THL1_RS06160 2917f5fb6cd06ba6930eba5879280107 651 Pfam PF13629 Pilus formation protein N terminal region 45 102 2.3E-11 T 13-09-2016 IPR032789 Pilus formation protein, N-terminal THL1_RS06160 2917f5fb6cd06ba6930eba5879280107 651 Pfam PF00263 Bacterial type II and III secretion system protein 436 617 1.9E-36 T 13-09-2016 IPR004846 Type II/III secretion system GO:0009306 THL1_RS06160 2917f5fb6cd06ba6930eba5879280107 651 PANTHER PTHR30332 349 617 2.9E-35 T 13-09-2016 THL1_RS06160 2917f5fb6cd06ba6930eba5879280107 651 PRINTS PR00811 Bacterial general secretion pathway protein D signature 356 366 1.0E-7 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS06160 2917f5fb6cd06ba6930eba5879280107 651 PRINTS PR00811 Bacterial general secretion pathway protein D signature 432 456 1.0E-7 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS06160 2917f5fb6cd06ba6930eba5879280107 651 PRINTS PR00811 Bacterial general secretion pathway protein D signature 604 618 1.0E-7 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS06160 2917f5fb6cd06ba6930eba5879280107 651 PRINTS PR00811 Bacterial general secretion pathway protein D signature 581 599 1.0E-7 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS06810 0edd2d121e4330438b81cd675533cfcd 431 PANTHER PTHR30035 1 430 2.7E-215 T 13-09-2016 IPR007428 MlaA lipoprotein GO:0016020 THL1_RS06810 0edd2d121e4330438b81cd675533cfcd 431 SUPERFAMILY SSF53474 92 233 5.46E-21 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS06810 0edd2d121e4330438b81cd675533cfcd 431 SUPERFAMILY SSF53474 332 416 5.46E-21 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS06810 0edd2d121e4330438b81cd675533cfcd 431 Gene3D G3DSA:3.40.50.1820 84 226 4.4E-13 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS06810 0edd2d121e4330438b81cd675533cfcd 431 Gene3D G3DSA:3.40.50.1820 325 417 4.4E-13 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS06810 0edd2d121e4330438b81cd675533cfcd 431 PANTHER PTHR30035:SF1 1 430 2.7E-215 T 13-09-2016 THL1_RS11600 f47bb6336dde5036dcfa9af4dcb5c56f 154 SMART SM00347 33 136 5.5E-15 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS11600 f47bb6336dde5036dcfa9af4dcb5c56f 154 Pfam PF01047 MarR family 40 103 2.6E-9 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS11600 f47bb6336dde5036dcfa9af4dcb5c56f 154 PANTHER PTHR33164 9 147 1.9E-55 T 13-09-2016 THL1_RS11600 f47bb6336dde5036dcfa9af4dcb5c56f 154 PANTHER PTHR33164:SF5 9 147 1.9E-55 T 13-09-2016 THL1_RS11600 f47bb6336dde5036dcfa9af4dcb5c56f 154 SUPERFAMILY SSF46785 9 150 6.23E-32 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11600 f47bb6336dde5036dcfa9af4dcb5c56f 154 Gene3D G3DSA:1.10.10.10 8 149 5.0E-38 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13265 318622f1c2711d1308c8b1193f83d7e6 372 SUPERFAMILY SSF111369 47 240 6.15E-16 T 13-09-2016 THL1_RS13265 318622f1c2711d1308c8b1193f83d7e6 372 PANTHER PTHR30469 5 367 8.0E-52 T 13-09-2016 THL1_RS13265 318622f1c2711d1308c8b1193f83d7e6 372 Gene3D G3DSA:2.40.50.100 63 91 9.1E-15 T 13-09-2016 THL1_RS13265 318622f1c2711d1308c8b1193f83d7e6 372 Gene3D G3DSA:2.40.50.100 166 197 9.1E-15 T 13-09-2016 THL1_RS13265 318622f1c2711d1308c8b1193f83d7e6 372 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 46 257 9.7E-17 T 13-09-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THL1_RS13265 318622f1c2711d1308c8b1193f83d7e6 372 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 33 355 1.9E-50 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS17395 952b738e780018b12d01afaf60c0268f 832 SUPERFAMILY SSF89796 7 415 5.76E-74 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS17395 952b738e780018b12d01afaf60c0268f 832 Gene3D G3DSA:3.40.50.10540 707 830 3.3E-67 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS17395 952b738e780018b12d01afaf60c0268f 832 Gene3D G3DSA:3.40.50.10540 435 644 3.3E-67 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS17395 952b738e780018b12d01afaf60c0268f 832 SUPERFAMILY SSF89796 434 821 1.05E-69 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS17395 952b738e780018b12d01afaf60c0268f 832 Pfam PF02515 CoA-transferase family III 9 396 4.7E-63 T 13-09-2016 IPR003673 CoA-transferase family III GO:0003824 THL1_RS17395 952b738e780018b12d01afaf60c0268f 832 Pfam PF02515 CoA-transferase family III 438 723 1.5E-58 T 13-09-2016 IPR003673 CoA-transferase family III GO:0003824 THL1_RS17395 952b738e780018b12d01afaf60c0268f 832 Gene3D G3DSA:3.40.50.10540 321 348 1.4E-92 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS17395 952b738e780018b12d01afaf60c0268f 832 Gene3D G3DSA:3.40.50.10540 3 284 1.4E-92 T 13-09-2016 IPR023606 CoA-transferase family III domain THL1_RS12645 384ae1ff12a8bd421cae1e8d7dae3fd3 292 PANTHER PTHR22911 11 291 4.4E-98 T 13-09-2016 THL1_RS12645 384ae1ff12a8bd421cae1e8d7dae3fd3 292 PANTHER PTHR22911:SF70 11 291 4.4E-98 T 13-09-2016 THL1_RS12645 384ae1ff12a8bd421cae1e8d7dae3fd3 292 SUPERFAMILY SSF103481 55 151 9.16E-15 T 13-09-2016 THL1_RS12645 384ae1ff12a8bd421cae1e8d7dae3fd3 292 Pfam PF00892 EamA-like transporter family 15 147 5.5E-16 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS12645 384ae1ff12a8bd421cae1e8d7dae3fd3 292 SUPERFAMILY SSF103481 194 290 3.4E-10 T 13-09-2016 THL1_RS16770 0da15e952711ba510733ca03a4d33487 298 Gene3D G3DSA:3.40.50.1820 81 173 1.9E-4 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS16770 0da15e952711ba510733ca03a4d33487 298 SUPERFAMILY SSF53474 87 239 9.62E-8 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS06635 e396b87ccf328f352129d8e203610a3a 306 Pfam PF04381 Putative exonuclease, RdgC 1 300 1.2E-115 T 13-09-2016 IPR007476 Putative exonuclease, RdgC GO:0006310 THL1_RS06635 e396b87ccf328f352129d8e203610a3a 306 PANTHER PTHR38103:SF1 2 305 1.2E-149 T 13-09-2016 THL1_RS06635 e396b87ccf328f352129d8e203610a3a 306 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 302 42.701 T 13-09-2016 IPR007476 Putative exonuclease, RdgC GO:0006310 THL1_RS06635 e396b87ccf328f352129d8e203610a3a 306 PANTHER PTHR38103 2 305 1.2E-149 T 13-09-2016 THL1_RS05580 d0fbad6084fa355fc5fec584cf79ff58 603 SUPERFAMILY SSF53822 446 597 2.26E-81 T 13-09-2016 IPR028082 Periplasmic binding protein-like I THL1_RS05580 d0fbad6084fa355fc5fec584cf79ff58 603 SUPERFAMILY SSF53822 250 418 2.26E-81 T 13-09-2016 IPR028082 Periplasmic binding protein-like I THL1_RS05580 d0fbad6084fa355fc5fec584cf79ff58 603 Pfam PF04348 LppC putative lipoprotein 33 593 6.1E-186 T 13-09-2016 IPR007443 Penicillin-binding protein activator LpoA THL1_RS05580 d0fbad6084fa355fc5fec584cf79ff58 603 PANTHER PTHR38038:SF1 1 600 8.4E-176 T 13-09-2016 THL1_RS05580 d0fbad6084fa355fc5fec584cf79ff58 603 Gene3D G3DSA:3.40.50.2300 360 522 3.3E-53 T 13-09-2016 THL1_RS05580 d0fbad6084fa355fc5fec584cf79ff58 603 PANTHER PTHR38038 1 600 8.4E-176 T 13-09-2016 THL1_RS05580 d0fbad6084fa355fc5fec584cf79ff58 603 Gene3D G3DSA:3.40.50.2300 523 586 5.3E-56 T 13-09-2016 THL1_RS05580 d0fbad6084fa355fc5fec584cf79ff58 603 Gene3D G3DSA:3.40.50.2300 249 358 5.3E-56 T 13-09-2016 THL1_RS22025 0c4246df7430c00b6cd926c0a656f01c 289 PANTHER PTHR11609 7 288 2.8E-155 T 13-09-2016 THL1_RS22025 0c4246df7430c00b6cd926c0a656f01c 289 Pfam PF01259 SAICAR synthetase 10 264 2.2E-106 T 13-09-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 THL1_RS22025 0c4246df7430c00b6cd926c0a656f01c 289 SUPERFAMILY SSF56104 6 288 2.26E-106 T 13-09-2016 THL1_RS22025 0c4246df7430c00b6cd926c0a656f01c 289 Gene3D G3DSA:3.30.200.20 5 114 1.2E-44 T 13-09-2016 THL1_RS22025 0c4246df7430c00b6cd926c0a656f01c 289 PANTHER PTHR11609:SF6 7 288 2.8E-155 T 13-09-2016 THL1_RS22025 0c4246df7430c00b6cd926c0a656f01c 289 Gene3D G3DSA:3.30.470.20 115 245 4.4E-58 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS22025 0c4246df7430c00b6cd926c0a656f01c 289 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 10 288 3.2E-91 T 13-09-2016 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 THL1_RS22025 0c4246df7430c00b6cd926c0a656f01c 289 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 9 289 27.337 T 13-09-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 THL1_RS22025 0c4246df7430c00b6cd926c0a656f01c 289 ProSitePatterns PS01058 SAICAR synthetase signature 2. 201 209 - T 13-09-2016 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 THL1_RS22110 ae67d235754e89e8d2641adcc8327ca1 231 PANTHER PTHR30625 10 231 5.8E-76 T 13-09-2016 THL1_RS22110 ae67d235754e89e8d2641adcc8327ca1 231 PANTHER PTHR30625:SF3 10 231 5.8E-76 T 13-09-2016 THL1_RS22110 ae67d235754e89e8d2641adcc8327ca1 231 TIGRFAM TIGR02796 tolQ: protein TolQ 10 224 3.3E-92 T 13-09-2016 IPR014163 Tol-Pal system, TolQ GO:0015031|GO:0016021 THL1_RS22110 ae67d235754e89e8d2641adcc8327ca1 231 Pfam PF01618 MotA/TolQ/ExbB proton channel family 84 210 1.2E-43 T 13-09-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 THL1_RS22700 8d1e1a7059587dc04405a5bc04cf13e9 268 PANTHER PTHR10108:SF886 21 266 3.6E-49 T 13-09-2016 THL1_RS22700 8d1e1a7059587dc04405a5bc04cf13e9 268 SUPERFAMILY SSF53335 5 256 1.23E-40 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS22700 8d1e1a7059587dc04405a5bc04cf13e9 268 PANTHER PTHR10108 21 266 3.6E-49 T 13-09-2016 THL1_RS22700 8d1e1a7059587dc04405a5bc04cf13e9 268 Gene3D G3DSA:3.40.50.150 67 196 6.7E-19 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS22700 8d1e1a7059587dc04405a5bc04cf13e9 268 Pfam PF13649 Methyltransferase domain 87 169 4.7E-10 T 13-09-2016 THL1_RS22700 8d1e1a7059587dc04405a5bc04cf13e9 268 PIRSF PIRSF018249 1 268 2.8E-87 T 13-09-2016 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 THL1_RS13900 5eabf71da90793e8307781ebc3aa9a8e 222 PANTHER PTHR13887:SF10 1 222 1.2E-38 T 13-09-2016 THL1_RS13900 5eabf71da90793e8307781ebc3aa9a8e 222 SUPERFAMILY SSF52833 3 211 3.08E-31 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS13900 5eabf71da90793e8307781ebc3aa9a8e 222 PANTHER PTHR13887 1 222 1.2E-38 T 13-09-2016 THL1_RS13900 5eabf71da90793e8307781ebc3aa9a8e 222 Gene3D G3DSA:3.40.30.10 1 208 1.0E-29 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS13900 5eabf71da90793e8307781ebc3aa9a8e 222 Pfam PF01323 DSBA-like thioredoxin domain 6 166 2.2E-23 T 13-09-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 THL1_RS21215 1024d8941c758fca769104f9149a97e2 370 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 147 357 2.4E-12 T 13-09-2016 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 THL1_RS21215 1024d8941c758fca769104f9149a97e2 370 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 28 104 6.3E-8 T 13-09-2016 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0008152|GO:0016788 THL1_RS21215 1024d8941c758fca769104f9149a97e2 370 Gene3D G3DSA:3.40.630.10 16 264 3.1E-14 T 13-09-2016 THL1_RS21215 1024d8941c758fca769104f9149a97e2 370 SUPERFAMILY SSF53187 143 363 6.95E-41 T 13-09-2016 THL1_RS21215 1024d8941c758fca769104f9149a97e2 370 SUPERFAMILY SSF53187 18 109 6.95E-41 T 13-09-2016 THL1_RS06355 166f54bbb7ef007516cb2ffcd5fbffee 253 Pfam PF00005 ABC transporter 29 177 6.9E-39 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS06355 166f54bbb7ef007516cb2ffcd5fbffee 253 PANTHER PTHR24220 15 253 9.7E-174 T 13-09-2016 THL1_RS06355 166f54bbb7ef007516cb2ffcd5fbffee 253 SUPERFAMILY SSF52540 13 247 3.63E-82 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06355 166f54bbb7ef007516cb2ffcd5fbffee 253 SMART SM00382 38 225 4.4E-18 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS06355 166f54bbb7ef007516cb2ffcd5fbffee 253 PIRSF PIRSF039085 10 253 1.1E-107 T 13-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 THL1_RS06355 166f54bbb7ef007516cb2ffcd5fbffee 253 Gene3D G3DSA:3.40.50.300 12 248 7.9E-85 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06355 166f54bbb7ef007516cb2ffcd5fbffee 253 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS06355 166f54bbb7ef007516cb2ffcd5fbffee 253 PANTHER PTHR24220:SF490 15 253 9.7E-174 T 13-09-2016 THL1_RS01345 867cea1531c3f672539e8d90d411ce77 191 SUPERFAMILY SSF52833 36 189 8.41E-15 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS01345 867cea1531c3f672539e8d90d411ce77 191 Gene3D G3DSA:3.40.30.10 39 145 8.0E-4 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS13455 caaff7c97ecc65f810c3c21773f0ef9f 304 Gene3D G3DSA:3.40.190.10 178 252 4.6E-10 T 13-09-2016 THL1_RS13455 caaff7c97ecc65f810c3c21773f0ef9f 304 PANTHER PTHR30126 3 290 2.0E-70 T 13-09-2016 THL1_RS13455 caaff7c97ecc65f810c3c21773f0ef9f 304 Gene3D G3DSA:3.40.190.10 105 177 6.6E-12 T 13-09-2016 THL1_RS13455 caaff7c97ecc65f810c3c21773f0ef9f 304 SUPERFAMILY SSF46785 4 87 9.12E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13455 caaff7c97ecc65f810c3c21773f0ef9f 304 Gene3D G3DSA:1.10.10.10 2 78 6.1E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13455 caaff7c97ecc65f810c3c21773f0ef9f 304 Pfam PF03466 LysR substrate binding domain 103 289 3.6E-27 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS13455 caaff7c97ecc65f810c3c21773f0ef9f 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 2.4E-21 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS13455 caaff7c97ecc65f810c3c21773f0ef9f 304 PANTHER PTHR30126:SF29 3 290 2.0E-70 T 13-09-2016 THL1_RS13455 caaff7c97ecc65f810c3c21773f0ef9f 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 5.6E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS13455 caaff7c97ecc65f810c3c21773f0ef9f 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 5.6E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS13455 caaff7c97ecc65f810c3c21773f0ef9f 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 5.6E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS13455 caaff7c97ecc65f810c3c21773f0ef9f 304 SUPERFAMILY SSF53850 103 289 3.8E-30 T 13-09-2016 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 SUPERFAMILY SSF52009 347 463 1.03E-34 T 13-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 481 780 5.7E-63 T 13-09-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 Gene3D G3DSA:3.20.20.60 481 785 1.7E-106 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 Gene3D G3DSA:3.30.1490.20 3 192 2.0E-66 T 13-09-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 693 711 - T 13-09-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 SUPERFAMILY SSF56059 3 384 1.53E-108 T 13-09-2016 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 Gene3D G3DSA:3.30.470.20 196 353 5.4E-62 T 13-09-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 PIRSF PIRSF000854 1 789 0.0 T 13-09-2016 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|UniPathway: UPA00138 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 5 786 0.0 T 13-09-2016 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|UniPathway: UPA00138 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 Pfam PF00391 PEP-utilising enzyme, mobile domain 383 454 7.5E-26 T 13-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 SUPERFAMILY SSF51621 461 786 1.26E-99 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 Gene3D G3DSA:3.50.30.10 354 459 4.9E-35 T 13-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 PANTHER PTHR22931 2 266 0.0 T 13-09-2016 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 PANTHER PTHR22931 282 786 0.0 T 13-09-2016 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 PANTHER PTHR22931:SF7 2 266 0.0 T 13-09-2016 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 PANTHER PTHR22931:SF7 282 786 0.0 T 13-09-2016 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 342 9.7E-120 T 13-09-2016 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 746 758 7.7E-6 T 13-09-2016 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 693 708 7.7E-6 T 13-09-2016 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 710 725 7.7E-6 T 13-09-2016 THL1_RS18160 6da7f0fa6c14f7b78c5dccad535141c2 789 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 413 424 - T 13-09-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 THL1_RS21405 9cb045be02dcb0209ad509624a7a9b88 230 Gene3D G3DSA:3.40.470.10 7 227 9.7E-103 T 13-09-2016 IPR005122 Uracil-DNA glycosylase-like THL1_RS21405 9cb045be02dcb0209ad509624a7a9b88 230 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 63 72 - T 13-09-2016 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 THL1_RS21405 9cb045be02dcb0209ad509624a7a9b88 230 PANTHER PTHR11264 9 229 4.6E-140 T 13-09-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 THL1_RS21405 9cb045be02dcb0209ad509624a7a9b88 230 SUPERFAMILY SSF52141 8 227 3.05E-95 T 13-09-2016 IPR005122 Uracil-DNA glycosylase-like THL1_RS21405 9cb045be02dcb0209ad509624a7a9b88 230 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 11 219 1.8E-83 T 13-09-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 THL1_RS21405 9cb045be02dcb0209ad509624a7a9b88 230 SMART SM00987 55 215 2.6E-37 T 13-09-2016 THL1_RS21405 9cb045be02dcb0209ad509624a7a9b88 230 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 10 226 41.005 T 13-09-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 THL1_RS21405 9cb045be02dcb0209ad509624a7a9b88 230 SMART SM00986 55 215 2.6E-37 T 13-09-2016 IPR005122 Uracil-DNA glycosylase-like THL1_RS21405 9cb045be02dcb0209ad509624a7a9b88 230 Pfam PF03167 Uracil DNA glycosylase superfamily 60 214 3.5E-22 T 13-09-2016 IPR005122 Uracil-DNA glycosylase-like THL1_RS05635 81ad4a76a516df4f10eeaf3d3a6b58ad 402 Hamap MF_00913 Putative lipid II flippase FtsW [ftsW]. 19 388 40.27 T 13-09-2016 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 THL1_RS05635 81ad4a76a516df4f10eeaf3d3a6b58ad 402 PANTHER PTHR30474 13 401 1.1E-159 T 13-09-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 THL1_RS05635 81ad4a76a516df4f10eeaf3d3a6b58ad 402 Pfam PF01098 Cell cycle protein 25 380 7.5E-107 T 13-09-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 THL1_RS05635 81ad4a76a516df4f10eeaf3d3a6b58ad 402 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 23 378 1.0E-129 T 13-09-2016 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 THL1_RS05635 81ad4a76a516df4f10eeaf3d3a6b58ad 402 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 337 361 - T 13-09-2016 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 THL1_RS05635 81ad4a76a516df4f10eeaf3d3a6b58ad 402 PANTHER PTHR30474:SF2 13 401 1.1E-159 T 13-09-2016 THL1_RS11125 5067d03529e897bdc9adb5e2d2f66278 298 Pfam PF03466 LysR substrate binding domain 90 295 3.7E-33 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS11125 5067d03529e897bdc9adb5e2d2f66278 298 SUPERFAMILY SSF53850 90 296 5.07E-38 T 13-09-2016 THL1_RS11125 5067d03529e897bdc9adb5e2d2f66278 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 8.4E-22 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS11125 5067d03529e897bdc9adb5e2d2f66278 298 Gene3D G3DSA:3.40.190.10 164 265 6.0E-22 T 13-09-2016 THL1_RS11125 5067d03529e897bdc9adb5e2d2f66278 298 Gene3D G3DSA:1.10.10.10 5 80 6.2E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11125 5067d03529e897bdc9adb5e2d2f66278 298 SUPERFAMILY SSF46785 5 90 5.28E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11125 5067d03529e897bdc9adb5e2d2f66278 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.0E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS11125 5067d03529e897bdc9adb5e2d2f66278 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.0E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS11125 5067d03529e897bdc9adb5e2d2f66278 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.0E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS11125 5067d03529e897bdc9adb5e2d2f66278 298 PANTHER PTHR30537:SF1 1 297 1.9E-174 T 13-09-2016 THL1_RS11125 5067d03529e897bdc9adb5e2d2f66278 298 PANTHER PTHR30537 1 297 1.9E-174 T 13-09-2016 THL1_RS04925 e1ae5e279f132d90d14d5dd6e84d9705 145 Pfam PF13633 Prokaryotic N-terminal methylation site 6 30 2.4E-6 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS04925 e1ae5e279f132d90d14d5dd6e84d9705 145 TIGRFAM TIGR02523 type_IV_pilV: type IV pilus modification protein PilV 6 126 1.8E-27 T 13-09-2016 IPR013362 Pilus modification type IV, PilV THL1_RS19445 61f6b4ce331a2156266c73da4f34c0f2 512 Pfam PF02120 Flagellar hook-length control protein FliK 416 496 6.1E-19 T 13-09-2016 IPR021136 Flagellar hook-length control protein-like, C-terminal THL1_RS26390 c81ffea29506e7f0b74326d35a9f04c5 285 Pfam PF00561 alpha/beta hydrolase fold 30 251 2.6E-29 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS26390 c81ffea29506e7f0b74326d35a9f04c5 285 SUPERFAMILY SSF53474 5 267 1.35E-53 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS26390 c81ffea29506e7f0b74326d35a9f04c5 285 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 2.7E-16 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS26390 c81ffea29506e7f0b74326d35a9f04c5 285 PRINTS PR00111 Alpha/beta hydrolase fold signature 112 125 2.7E-16 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS26390 c81ffea29506e7f0b74326d35a9f04c5 285 PRINTS PR00111 Alpha/beta hydrolase fold signature 213 227 2.7E-16 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS26390 c81ffea29506e7f0b74326d35a9f04c5 285 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 2.7E-16 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS26390 c81ffea29506e7f0b74326d35a9f04c5 285 TIGRFAM TIGR02240 PHA_depoly_arom: poly(3-hydroxyalkanoate) depolymerase 4 278 1.8E-186 T 13-09-2016 IPR011942 Poly(3-hydroxyalkanoate) depolymerase KEGG: 00051+3.1.1.-|KEGG: 00053+3.1.1.-|KEGG: 00363+3.1.1.-|KEGG: 00365+3.1.1.-|KEGG: 00534+3.1.1.-|KEGG: 00564+3.1.1.-|KEGG: 00623+3.1.1.-|KEGG: 00640+3.1.1.-|KEGG: 00830+3.1.1.-|KEGG: 00900+3.1.1.-|KEGG: 00940+3.1.1.-|KEGG: 00960+3.1.1.- THL1_RS26390 c81ffea29506e7f0b74326d35a9f04c5 285 PANTHER PTHR10992 8 268 9.9E-37 T 13-09-2016 THL1_RS26390 c81ffea29506e7f0b74326d35a9f04c5 285 Gene3D G3DSA:3.40.50.1820 5 268 4.3E-53 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS21860 f9ad394f090d82fed6c6efeb948bbd35 243 PANTHER PTHR10672 7 235 9.3E-55 T 13-09-2016 THL1_RS21860 f9ad394f090d82fed6c6efeb948bbd35 243 SMART SM01007 11 192 1.1E-49 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS21860 f9ad394f090d82fed6c6efeb948bbd35 243 Gene3D G3DSA:3.40.225.10 6 217 1.8E-53 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS21860 f9ad394f090d82fed6c6efeb948bbd35 243 SUPERFAMILY SSF53639 3 220 6.28E-57 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS21860 f9ad394f090d82fed6c6efeb948bbd35 243 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 12 192 1.2E-43 T 13-09-2016 IPR001303 Class II aldolase/adducin N-terminal THL1_RS14460 536b2cc12e3feb07fd18bd655e64d014 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.7E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14460 536b2cc12e3feb07fd18bd655e64d014 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 1.7E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14460 536b2cc12e3feb07fd18bd655e64d014 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.7E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14460 536b2cc12e3feb07fd18bd655e64d014 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 1.7E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14460 536b2cc12e3feb07fd18bd655e64d014 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.7E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14460 536b2cc12e3feb07fd18bd655e64d014 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 1.7E-42 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14460 536b2cc12e3feb07fd18bd655e64d014 259 Gene3D G3DSA:3.40.50.720 6 254 2.0E-71 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS14460 536b2cc12e3feb07fd18bd655e64d014 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 250 2.5E-56 T 13-09-2016 THL1_RS14460 536b2cc12e3feb07fd18bd655e64d014 259 PANTHER PTHR24322 165 197 1.3E-40 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14460 536b2cc12e3feb07fd18bd655e64d014 259 PANTHER PTHR24322 13 148 1.3E-40 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14460 536b2cc12e3feb07fd18bd655e64d014 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.3E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14460 536b2cc12e3feb07fd18bd655e64d014 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 2.3E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14460 536b2cc12e3feb07fd18bd655e64d014 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 2.3E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS14460 536b2cc12e3feb07fd18bd655e64d014 259 SUPERFAMILY SSF51735 7 252 2.53E-71 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS11675 d81ec12fc73b2a8f6389cef1058cbdee 172 PANTHER PTHR30173 16 163 6.5E-37 T 13-09-2016 THL1_RS11675 d81ec12fc73b2a8f6389cef1058cbdee 172 Pfam PF04542 Sigma-70 region 2 16 79 2.0E-13 T 13-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS11675 d81ec12fc73b2a8f6389cef1058cbdee 172 PANTHER PTHR30173:SF9 16 163 6.5E-37 T 13-09-2016 THL1_RS11675 d81ec12fc73b2a8f6389cef1058cbdee 172 Gene3D G3DSA:1.10.10.10 108 164 3.2E-11 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11675 d81ec12fc73b2a8f6389cef1058cbdee 172 Pfam PF08281 Sigma-70, region 4 111 163 4.0E-13 T 13-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS11675 d81ec12fc73b2a8f6389cef1058cbdee 172 SUPERFAMILY SSF88946 9 77 1.65E-13 T 13-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS11675 d81ec12fc73b2a8f6389cef1058cbdee 172 Gene3D G3DSA:1.10.1740.10 16 103 5.9E-12 T 13-09-2016 THL1_RS11675 d81ec12fc73b2a8f6389cef1058cbdee 172 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 163 4.8E-19 T 13-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS11675 d81ec12fc73b2a8f6389cef1058cbdee 172 SUPERFAMILY SSF88659 93 167 6.92E-13 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS23150 325ac4c0861fb64ecd1135d65b538d0d 123 Gene3D G3DSA:1.25.40.10 22 105 7.1E-5 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS02990 0e16edf3277e2978816fe95ea021df83 264 PIRSF PIRSF003092 2 264 5.1E-68 T 13-09-2016 IPR025501 ATP binding protein MinD THL1_RS02990 0e16edf3277e2978816fe95ea021df83 264 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 9 176 9.9E-23 T 13-09-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THL1_RS02990 0e16edf3277e2978816fe95ea021df83 264 PANTHER PTHR13696:SF3 1 255 1.6E-83 T 13-09-2016 THL1_RS02990 0e16edf3277e2978816fe95ea021df83 264 PANTHER PTHR13696 1 255 1.6E-83 T 13-09-2016 THL1_RS02990 0e16edf3277e2978816fe95ea021df83 264 Gene3D G3DSA:3.40.50.300 7 243 3.3E-49 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS02990 0e16edf3277e2978816fe95ea021df83 264 SUPERFAMILY SSF52540 7 260 4.19E-48 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS12585 a44af10f488c34771ff3d2472d43b465 318 Gene3D G3DSA:3.40.190.10 184 270 3.6E-15 T 13-09-2016 THL1_RS12585 a44af10f488c34771ff3d2472d43b465 318 PANTHER PTHR30537 2 317 8.2E-99 T 13-09-2016 THL1_RS12585 a44af10f488c34771ff3d2472d43b465 318 SUPERFAMILY SSF46785 10 118 3.87E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12585 a44af10f488c34771ff3d2472d43b465 318 Gene3D G3DSA:3.40.190.10 98 183 1.3E-26 T 13-09-2016 THL1_RS12585 a44af10f488c34771ff3d2472d43b465 318 PANTHER PTHR30537:SF5 2 317 8.2E-99 T 13-09-2016 THL1_RS12585 a44af10f488c34771ff3d2472d43b465 318 Pfam PF03466 LysR substrate binding domain 94 299 2.9E-42 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS12585 a44af10f488c34771ff3d2472d43b465 318 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 69 1.2E-19 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS12585 a44af10f488c34771ff3d2472d43b465 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 3.6E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS12585 a44af10f488c34771ff3d2472d43b465 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 3.6E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS12585 a44af10f488c34771ff3d2472d43b465 318 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 3.6E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS12585 a44af10f488c34771ff3d2472d43b465 318 SUPERFAMILY SSF53850 94 305 7.45E-43 T 13-09-2016 THL1_RS12585 a44af10f488c34771ff3d2472d43b465 318 Gene3D G3DSA:1.10.10.10 12 92 1.5E-24 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12975 30bd872d1370035e6752561554b706a4 168 PANTHER PTHR23091:SF237 1 168 3.9E-30 T 13-09-2016 THL1_RS12975 30bd872d1370035e6752561554b706a4 168 PANTHER PTHR23091 1 168 3.9E-30 T 13-09-2016 THL1_RS12975 30bd872d1370035e6752561554b706a4 168 SUPERFAMILY SSF55729 1 145 1.29E-28 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS12975 30bd872d1370035e6752561554b706a4 168 Pfam PF13527 Acetyltransferase (GNAT) domain 5 129 4.1E-13 T 13-09-2016 THL1_RS12975 30bd872d1370035e6752561554b706a4 168 Gene3D G3DSA:3.40.630.30 1 130 8.6E-21 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS05135 af2d9affeb3e06dbba718be2960f5834 260 Gene3D G3DSA:3.20.20.140 1 257 6.3E-78 T 13-09-2016 THL1_RS05135 af2d9affeb3e06dbba718be2960f5834 260 PANTHER PTHR10060 1 259 2.1E-81 T 13-09-2016 IPR001130 TatD family GO:0016788 THL1_RS05135 af2d9affeb3e06dbba718be2960f5834 260 Pfam PF01026 TatD related DNase 3 255 8.0E-63 T 13-09-2016 IPR001130 TatD family GO:0016788 THL1_RS05135 af2d9affeb3e06dbba718be2960f5834 260 PIRSF PIRSF005902 1 259 1.0E-68 T 13-09-2016 IPR001130 TatD family GO:0016788 THL1_RS05135 af2d9affeb3e06dbba718be2960f5834 260 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 192 208 - T 13-09-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 THL1_RS05135 af2d9affeb3e06dbba718be2960f5834 260 SUPERFAMILY SSF51556 2 257 1.16E-76 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS05135 af2d9affeb3e06dbba718be2960f5834 260 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 13-09-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 THL1_RS14535 2f3794b1e60e261b3ce2cc5f5432264d 326 PANTHER PTHR11624 1 322 1.9E-140 T 13-09-2016 IPR033247 Transketolase family THL1_RS14535 2f3794b1e60e261b3ce2cc5f5432264d 326 Pfam PF02780 Transketolase, C-terminal domain 193 315 3.3E-35 T 13-09-2016 IPR033248 Transketolase, C-terminal domain THL1_RS14535 2f3794b1e60e261b3ce2cc5f5432264d 326 SMART SM00861 1 170 3.4E-50 T 13-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain THL1_RS14535 2f3794b1e60e261b3ce2cc5f5432264d 326 Pfam PF02779 Transketolase, pyrimidine binding domain 2 167 8.3E-42 T 13-09-2016 IPR005475 Transketolase-like, pyrimidine-binding domain THL1_RS14535 2f3794b1e60e261b3ce2cc5f5432264d 326 SUPERFAMILY SSF52922 188 321 1.7E-38 T 13-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THL1_RS14535 2f3794b1e60e261b3ce2cc5f5432264d 326 Gene3D G3DSA:3.40.50.920 197 318 4.8E-41 T 13-09-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 THL1_RS14535 2f3794b1e60e261b3ce2cc5f5432264d 326 PANTHER PTHR11624:SF77 1 322 1.9E-140 T 13-09-2016 THL1_RS14535 2f3794b1e60e261b3ce2cc5f5432264d 326 SUPERFAMILY SSF52518 2 203 3.48E-60 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS14535 2f3794b1e60e261b3ce2cc5f5432264d 326 Gene3D G3DSA:3.40.50.970 2 195 3.7E-71 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS03530 24ebb17d0ea271fb1ca3d2b662857c1f 200 Gene3D G3DSA:3.40.1370.10 52 199 3.5E-58 T 13-09-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 THL1_RS03530 24ebb17d0ea271fb1ca3d2b662857c1f 200 PANTHER PTHR10746 10 200 8.2E-89 T 13-09-2016 IPR013005 50S ribosomal protein uL4 THL1_RS03530 24ebb17d0ea271fb1ca3d2b662857c1f 200 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 6 200 34.057 T 13-09-2016 IPR013005 50S ribosomal protein uL4 THL1_RS03530 24ebb17d0ea271fb1ca3d2b662857c1f 200 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 11 197 1.7E-74 T 13-09-2016 IPR013005 50S ribosomal protein uL4 THL1_RS03530 24ebb17d0ea271fb1ca3d2b662857c1f 200 Pfam PF00573 Ribosomal protein L4/L1 family 11 197 6.6E-64 T 13-09-2016 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 THL1_RS03530 24ebb17d0ea271fb1ca3d2b662857c1f 200 SUPERFAMILY SSF52166 6 199 5.23E-73 T 13-09-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 THL1_RS01525 fc0e908dbfbd0745032e6f7f5f3c6191 121 Pfam PF00072 Response regulator receiver domain 4 115 4.3E-28 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS01525 fc0e908dbfbd0745032e6f7f5f3c6191 121 SMART SM00448 2 115 1.0E-38 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS01525 fc0e908dbfbd0745032e6f7f5f3c6191 121 Gene3D G3DSA:3.40.50.2300 1 120 2.9E-39 T 13-09-2016 THL1_RS01525 fc0e908dbfbd0745032e6f7f5f3c6191 121 SUPERFAMILY SSF52172 1 120 1.71E-38 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS01525 fc0e908dbfbd0745032e6f7f5f3c6191 121 PANTHER PTHR26402 2 121 1.6E-41 T 13-09-2016 THL1_RS02405 c471ce76ec49e1c3616ed1f4a53d0a17 471 ProSitePatterns PS00218 Amino acid permeases signature. 51 81 - T 13-09-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 THL1_RS02405 c471ce76ec49e1c3616ed1f4a53d0a17 471 Pfam PF00324 Amino acid permease 27 458 2.0E-88 T 13-09-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 THL1_RS02405 c471ce76ec49e1c3616ed1f4a53d0a17 471 PANTHER PTHR11785 14 455 2.8E-202 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS02405 c471ce76ec49e1c3616ed1f4a53d0a17 471 PANTHER PTHR11785:SF317 14 455 2.8E-202 T 13-09-2016 THL1_RS02405 c471ce76ec49e1c3616ed1f4a53d0a17 471 PIRSF PIRSF006060 9 467 1.6E-70 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS18475 0cdc98c8819808db0a3fa7bc1d4f090d 551 PANTHER PTHR10617 2 474 1.0E-248 T 13-09-2016 THL1_RS18475 0cdc98c8819808db0a3fa7bc1d4f090d 551 SUPERFAMILY SSF51905 308 449 1.12E-56 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS18475 0cdc98c8819808db0a3fa7bc1d4f090d 551 SUPERFAMILY SSF51905 5 212 1.12E-56 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS18475 0cdc98c8819808db0a3fa7bc1d4f090d 551 SUPERFAMILY SSF54862 451 551 2.19E-28 T 13-09-2016 THL1_RS18475 0cdc98c8819808db0a3fa7bc1d4f090d 551 Pfam PF13450 NAD(P)-binding Rossmann-like domain 12 57 1.5E-7 T 13-09-2016 THL1_RS18475 0cdc98c8819808db0a3fa7bc1d4f090d 551 Gene3D G3DSA:3.50.50.60 6 283 3.7E-43 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS18475 0cdc98c8819808db0a3fa7bc1d4f090d 551 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 447 548 3.7E-50 T 13-09-2016 IPR007859 ETF-QO/FixX GO:0051536|GO:0055114 THL1_RS18475 0cdc98c8819808db0a3fa7bc1d4f090d 551 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 180 195 9.4E-7 T 13-09-2016 THL1_RS18475 0cdc98c8819808db0a3fa7bc1d4f090d 551 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 9.4E-7 T 13-09-2016 THL1_RS18475 0cdc98c8819808db0a3fa7bc1d4f090d 551 PANTHER PTHR10617:SF107 2 474 1.0E-248 T 13-09-2016 IPR007859 ETF-QO/FixX GO:0051536|GO:0055114 THL1_RS18475 0cdc98c8819808db0a3fa7bc1d4f090d 551 SUPERFAMILY SSF54373 212 307 9.42E-37 T 13-09-2016 THL1_RS12310 8815b6fd2383443dd2743afdeed02c9d 199 PANTHER PTHR38477 47 188 3.0E-29 T 13-09-2016 THL1_RS12310 8815b6fd2383443dd2743afdeed02c9d 199 Pfam PF13645 L,D-transpeptidase catalytic domain 44 188 2.2E-39 T 13-09-2016 IPR032676 Putative L,D-transpeptidase catalytic domain THL1_RS12310 8815b6fd2383443dd2743afdeed02c9d 199 PANTHER PTHR38477:SF1 47 188 3.0E-29 T 13-09-2016 THL1_RS05105 689b731b6a8ab23e14566d2f9f6964af 282 Gene3D G3DSA:3.90.1170.20 10 135 5.6E-52 T 13-09-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 THL1_RS05105 689b731b6a8ab23e14566d2f9f6964af 282 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 25 113 4.1E-27 T 13-09-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 THL1_RS05105 689b731b6a8ab23e14566d2f9f6964af 282 SUPERFAMILY SSF51690 115 280 1.84E-58 T 13-09-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 THL1_RS05105 689b731b6a8ab23e14566d2f9f6964af 282 Gene3D G3DSA:3.20.20.70 136 269 5.6E-59 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS05105 689b731b6a8ab23e14566d2f9f6964af 282 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 17 279 7.8E-97 T 13-09-2016 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|UniPathway: UPA00253 THL1_RS05105 689b731b6a8ab23e14566d2f9f6964af 282 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 115 279 1.9E-56 T 13-09-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 THL1_RS05105 689b731b6a8ab23e14566d2f9f6964af 282 SUPERFAMILY SSF54675 10 114 2.0E-32 T 13-09-2016 THL1_RS05105 689b731b6a8ab23e14566d2f9f6964af 282 PIRSF PIRSF006250 7 282 6.2E-106 T 13-09-2016 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD THL1_RS05105 689b731b6a8ab23e14566d2f9f6964af 282 PANTHER PTHR32179 1 280 9.0E-125 T 13-09-2016 THL1_RS12185 dc16ba674cff5fa680253b1ab07ccd92 383 PANTHER PTHR36195:SF3 80 376 6.7E-61 T 13-09-2016 THL1_RS12185 dc16ba674cff5fa680253b1ab07ccd92 383 Pfam PF00199 Catalase 73 186 6.8E-10 T 13-09-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS12185 dc16ba674cff5fa680253b1ab07ccd92 383 Gene3D G3DSA:2.40.180.10 48 376 1.2E-46 T 13-09-2016 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS12185 dc16ba674cff5fa680253b1ab07ccd92 383 PANTHER PTHR36195 80 376 6.7E-61 T 13-09-2016 THL1_RS12185 dc16ba674cff5fa680253b1ab07ccd92 383 SUPERFAMILY SSF56634 21 376 7.46E-79 T 13-09-2016 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 THL1_RS00440 090996fb20c4f779d9a94c183df0c65a 562 Pfam PF01895 PhoU domain 340 423 4.4E-12 T 13-09-2016 IPR026022 PhoU domain THL1_RS00440 090996fb20c4f779d9a94c183df0c65a 562 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 1 308 3.5E-103 T 13-09-2016 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 THL1_RS00440 090996fb20c4f779d9a94c183df0c65a 562 SUPERFAMILY SSF109755 320 532 5.76E-35 T 13-09-2016 THL1_RS00440 090996fb20c4f779d9a94c183df0c65a 562 PANTHER PTHR10010 1 446 3.6E-39 T 13-09-2016 THL1_RS00440 090996fb20c4f779d9a94c183df0c65a 562 Pfam PF02690 Na+/Pi-cotransporter 13 147 4.5E-34 T 13-09-2016 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: REACT_15518 THL1_RS00440 090996fb20c4f779d9a94c183df0c65a 562 Pfam PF02690 Na+/Pi-cotransporter 158 260 3.2E-11 T 13-09-2016 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: REACT_15518 THL1_RS00440 090996fb20c4f779d9a94c183df0c65a 562 Gene3D G3DSA:1.20.58.220 327 425 1.7E-12 T 13-09-2016 THL1_RS00440 090996fb20c4f779d9a94c183df0c65a 562 PANTHER PTHR10010:SF26 1 446 3.6E-39 T 13-09-2016 THL1_RS00440 090996fb20c4f779d9a94c183df0c65a 562 TIGRFAM TIGR01013 2a58: sodium-dependent inorganic phosphate (Pi) transporter 67 521 1.2E-112 T 13-09-2016 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: REACT_15518 THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 SUPERFAMILY SSF82866 298 491 9.42E-36 T 13-09-2016 THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 SUPERFAMILY SSF82693 271 326 1.46E-16 T 13-09-2016 THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 SUPERFAMILY SSF82693 139 185 1.46E-16 T 13-09-2016 THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 SUPERFAMILY SSF82714 708 792 3.14E-14 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 SUPERFAMILY SSF82714 188 268 6.8E-14 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 PANTHER PTHR32063 4 1016 0.0 T 13-09-2016 THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 PANTHER PTHR32063:SF18 4 1016 0.0 T 13-09-2016 THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 Gene3D G3DSA:1.10.3850.10 277 491 1.2E-44 T 13-09-2016 THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 Gene3D G3DSA:1.10.3850.10 799 1011 2.0E-51 T 13-09-2016 THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 SUPERFAMILY SSF82693 43 138 8.72E-15 T 13-09-2016 THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 SUPERFAMILY SSF82866 791 1014 3.27E-45 T 13-09-2016 THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 Gene3D G3DSA:3.30.2090.10 707 792 2.0E-14 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 Gene3D G3DSA:3.30.70.1430 44 142 6.3E-16 T 13-09-2016 THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 PRINTS PR00702 Acriflavin resistance protein family signature 440 463 2.5E-18 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 PRINTS PR00702 Acriflavin resistance protein family signature 465 488 2.5E-18 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 2.5E-18 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 2.5E-18 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 PRINTS PR00702 Acriflavin resistance protein family signature 387 411 2.5E-18 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 Gene3D G3DSA:3.30.2090.10 188 270 3.7E-15 T 13-09-2016 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THL1_RS13270 67796ec1275ca547f5720fb0d41cbb2a 1031 Pfam PF00873 AcrB/AcrD/AcrF family 8 1007 1.3E-157 T 13-09-2016 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 THL1_RS06470 c82bad20b69fe3c10c13b7887dbb640f 471 PANTHER PTHR24960 3 391 3.9E-163 T 13-09-2016 THL1_RS06470 c82bad20b69fe3c10c13b7887dbb640f 471 PANTHER PTHR24960:SF45 3 391 3.9E-163 T 13-09-2016 THL1_RS06470 c82bad20b69fe3c10c13b7887dbb640f 471 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 271 282 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS06470 c82bad20b69fe3c10c13b7887dbb640f 471 Pfam PF12801 4Fe-4S binding domain 96 126 2.9E-6 T 13-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THL1_RS06470 c82bad20b69fe3c10c13b7887dbb640f 471 Gene3D G3DSA:3.30.70.20 212 306 8.5E-9 T 13-09-2016 THL1_RS06470 c82bad20b69fe3c10c13b7887dbb640f 471 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 353 469 1.2E-27 T 13-09-2016 IPR032879 FixG, C-terminal immunoglobulin-like domain THL1_RS06470 c82bad20b69fe3c10c13b7887dbb640f 471 SUPERFAMILY SSF54862 104 132 2.21E-30 T 13-09-2016 THL1_RS06470 c82bad20b69fe3c10c13b7887dbb640f 471 SUPERFAMILY SSF54862 173 357 2.21E-30 T 13-09-2016 THL1_RS06470 c82bad20b69fe3c10c13b7887dbb640f 471 Gene3D G3DSA:2.60.40.10 354 470 1.7E-31 T 13-09-2016 IPR013783 Immunoglobulin-like fold THL1_RS06470 c82bad20b69fe3c10c13b7887dbb640f 471 Pfam PF13746 4Fe-4S dicluster domain 218 324 1.9E-42 T 13-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THL1_RS06470 c82bad20b69fe3c10c13b7887dbb640f 471 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 40 468 8.9E-167 T 13-09-2016 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021 THL1_RS09495 b1348cd539f40cf04344374ab0553c89 117 ProSitePatterns PS00769 Transthyretin signature 2. 100 112 - T 13-09-2016 IPR023419 Transthyretin, conserved site THL1_RS09495 b1348cd539f40cf04344374ab0553c89 117 PANTHER PTHR10395 1 117 2.5E-46 T 13-09-2016 THL1_RS09495 b1348cd539f40cf04344374ab0553c89 117 PRINTS PR00189 Transthyretin signature 3 23 4.0E-8 T 13-09-2016 IPR000895 Transthyretin/hydroxyisourate hydrolase THL1_RS09495 b1348cd539f40cf04344374ab0553c89 117 PRINTS PR00189 Transthyretin signature 95 117 4.0E-8 T 13-09-2016 IPR000895 Transthyretin/hydroxyisourate hydrolase THL1_RS09495 b1348cd539f40cf04344374ab0553c89 117 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 2 117 5.6E-40 T 13-09-2016 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394 THL1_RS09495 b1348cd539f40cf04344374ab0553c89 117 Pfam PF00576 HIUase/Transthyretin family 4 116 1.7E-35 T 13-09-2016 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily THL1_RS09495 b1348cd539f40cf04344374ab0553c89 117 ProSitePatterns PS00768 Transthyretin signature 1. 7 22 - T 13-09-2016 IPR023418 Transthyretin, thyroxine binding site THL1_RS09495 b1348cd539f40cf04344374ab0553c89 117 PANTHER PTHR10395:SF7 1 117 2.5E-46 T 13-09-2016 THL1_RS09495 b1348cd539f40cf04344374ab0553c89 117 Gene3D G3DSA:2.60.40.180 2 117 2.0E-37 T 13-09-2016 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily THL1_RS09495 b1348cd539f40cf04344374ab0553c89 117 SUPERFAMILY SSF49472 1 117 8.24E-42 T 13-09-2016 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 SUPERFAMILY SSF50621 245 386 2.51E-30 T 13-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 74 86 1.1E-17 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 54 72 1.1E-17 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 261 280 1.1E-17 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 177 190 1.1E-17 T 13-09-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 PANTHER PTHR11482 3 386 2.0E-130 T 13-09-2016 THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 PANTHER PTHR11482:SF6 3 386 2.0E-130 T 13-09-2016 THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 Gene3D G3DSA:2.40.37.10 256 386 1.1E-27 T 13-09-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 SUPERFAMILY SSF51419 25 273 9.16E-66 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 45 272 2.2E-54 T 13-09-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 216 229 - T 13-09-2016 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Reactome: REACT_13 THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 276 384 4.9E-16 T 13-09-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 54 72 - T 13-09-2016 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Reactome: REACT_13 THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 Gene3D G3DSA:3.20.20.10 35 255 4.9E-65 T 13-09-2016 IPR029066 PLP-binding barrel THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 PRINTS PR01182 Ornithine decarboxylase signature 52 79 3.6E-19 T 13-09-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 PRINTS PR01182 Ornithine decarboxylase signature 126 148 3.6E-19 T 13-09-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 PRINTS PR01182 Ornithine decarboxylase signature 329 339 3.6E-19 T 13-09-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 PRINTS PR01182 Ornithine decarboxylase signature 26 50 3.6E-19 T 13-09-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 THL1_RS05170 c963d0d3b978103aa758a7ca01842db5 387 PRINTS PR01182 Ornithine decarboxylase signature 96 120 3.6E-19 T 13-09-2016 IPR002433 Ornithine decarboxylase GO:0006596 Reactome: REACT_13 THL1_RS16675 83076dad05dc252e8ec65a57a21ff93e 234 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 25 222 3.1E-17 T 13-09-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 THL1_RS16675 83076dad05dc252e8ec65a57a21ff93e 234 PANTHER PTHR31272 20 234 1.5E-20 T 13-09-2016 THL1_RS24985 f2cf76b74ad5f5af6395ae170d00f105 171 PANTHER PTHR30529 1 169 7.0E-19 T 13-09-2016 THL1_RS24985 f2cf76b74ad5f5af6395ae170d00f105 171 Pfam PF01292 Prokaryotic cytochrome b561 5 169 2.1E-19 T 13-09-2016 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THL1_RS24985 f2cf76b74ad5f5af6395ae170d00f105 171 SUPERFAMILY SSF81342 3 170 1.33E-18 T 13-09-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 THL1_RS16835 067efb6d6a25d7065b1b2569fae840f1 462 Pfam PF00324 Amino acid permease 14 450 8.7E-106 T 13-09-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 THL1_RS16835 067efb6d6a25d7065b1b2569fae840f1 462 PANTHER PTHR11785 2 453 8.6E-221 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS16835 067efb6d6a25d7065b1b2569fae840f1 462 ProSitePatterns PS00218 Amino acid permeases signature. 39 69 - T 13-09-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 THL1_RS16835 067efb6d6a25d7065b1b2569fae840f1 462 PIRSF PIRSF006060 1 456 1.1E-66 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS16835 067efb6d6a25d7065b1b2569fae840f1 462 PANTHER PTHR11785:SF351 2 453 8.6E-221 T 13-09-2016 THL1_RS02205 9acbcdd134d4019a7a2ccb555bf4bc29 598 PANTHER PTHR10909 1 475 1.4E-268 T 13-09-2016 THL1_RS02205 9acbcdd134d4019a7a2ccb555bf4bc29 598 SUPERFAMILY SSF47203 286 474 8.22E-51 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS02205 9acbcdd134d4019a7a2ccb555bf4bc29 598 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 30 4.2E-9 T 13-09-2016 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria THL1_RS02205 9acbcdd134d4019a7a2ccb555bf4bc29 598 SUPERFAMILY SSF56645 36 278 2.36E-59 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS02205 9acbcdd134d4019a7a2ccb555bf4bc29 598 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 281 450 1.7E-23 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS02205 9acbcdd134d4019a7a2ccb555bf4bc29 598 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 270 1.8E-18 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS02205 9acbcdd134d4019a7a2ccb555bf4bc29 598 Gene3D G3DSA:1.10.540.10 35 158 1.4E-19 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS02205 9acbcdd134d4019a7a2ccb555bf4bc29 598 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 39 156 2.9E-13 T 13-09-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 THL1_RS02205 9acbcdd134d4019a7a2ccb555bf4bc29 598 Gene3D G3DSA:1.20.140.10 267 461 1.1E-52 T 13-09-2016 THL1_RS02205 9acbcdd134d4019a7a2ccb555bf4bc29 598 PANTHER PTHR10909:SF296 1 475 1.4E-268 T 13-09-2016 THL1_RS02205 9acbcdd134d4019a7a2ccb555bf4bc29 598 Gene3D G3DSA:2.40.110.10 160 266 8.7E-28 T 13-09-2016 THL1_RS02205 9acbcdd134d4019a7a2ccb555bf4bc29 598 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 466 592 5.4E-37 T 13-09-2016 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain THL1_RS27455 91001e52af0e60e2a2aab3cc9d5b5564 360 Gene3D G3DSA:3.30.565.10 216 297 4.4E-5 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS27455 91001e52af0e60e2a2aab3cc9d5b5564 360 Pfam PF06580 Histidine kinase 162 240 9.3E-23 T 13-09-2016 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 THL1_RS27455 91001e52af0e60e2a2aab3cc9d5b5564 360 SUPERFAMILY SSF55874 216 298 2.11E-5 T 13-09-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain THL1_RS27455 91001e52af0e60e2a2aab3cc9d5b5564 360 PANTHER PTHR34220 9 356 2.8E-97 T 13-09-2016 THL1_RS27455 91001e52af0e60e2a2aab3cc9d5b5564 360 PANTHER PTHR34220:SF3 9 356 2.8E-97 T 13-09-2016 THL1_RS20500 034633866efd2b27bf81c68635de1ffc 467 Pfam PF07044 Protein of unknown function (DUF1329) 87 443 2.0E-107 T 13-09-2016 IPR010752 Protein of unknown function DUF1329 THL1_RS20500 034633866efd2b27bf81c68635de1ffc 467 Gene3D G3DSA:2.50.20.10 351 433 3.0E-31 T 13-09-2016 THL1_RS20500 034633866efd2b27bf81c68635de1ffc 467 Gene3D G3DSA:2.50.20.10 169 319 3.0E-31 T 13-09-2016 THL1_RS26955 30393debda53f9717ad621ae1d409781 664 SUPERFAMILY SSF52540 190 415 4.56E-45 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26955 30393debda53f9717ad621ae1d409781 664 SUPERFAMILY SSF52540 578 644 4.56E-45 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26955 30393debda53f9717ad621ae1d409781 664 SUPERFAMILY SSF52540 15 144 4.56E-45 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26955 30393debda53f9717ad621ae1d409781 664 SUPERFAMILY SSF52540 493 541 4.56E-45 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26955 30393debda53f9717ad621ae1d409781 664 Gene3D G3DSA:3.40.50.300 299 347 1.3E-9 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26955 30393debda53f9717ad621ae1d409781 664 Gene3D G3DSA:3.40.50.300 571 642 1.3E-9 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26955 30393debda53f9717ad621ae1d409781 664 PANTHER PTHR11070 17 506 3.5E-20 T 13-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 THL1_RS26955 30393debda53f9717ad621ae1d409781 664 PANTHER PTHR11070 563 637 3.5E-20 T 13-09-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 THL1_RS26955 30393debda53f9717ad621ae1d409781 664 Gene3D G3DSA:3.40.50.300 18 98 5.0E-33 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26955 30393debda53f9717ad621ae1d409781 664 Gene3D G3DSA:3.40.50.300 204 298 5.0E-33 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26955 30393debda53f9717ad621ae1d409781 664 Pfam PF00580 UvrD/REP helicase N-terminal domain 17 284 6.4E-18 T 13-09-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 THL1_RS14365 f8abfb72b9671e486088f25f6b988981 353 PANTHER PTHR12169 17 345 1.5E-104 T 13-09-2016 IPR005654 ATPase, AFG1-like GO:0005524 THL1_RS14365 f8abfb72b9671e486088f25f6b988981 353 Pfam PF03969 AFG1-like ATPase 13 345 1.3E-95 T 13-09-2016 IPR005654 ATPase, AFG1-like GO:0005524 THL1_RS14365 f8abfb72b9671e486088f25f6b988981 353 PANTHER PTHR12169:SF11 17 345 1.5E-104 T 13-09-2016 THL1_RS14365 f8abfb72b9671e486088f25f6b988981 353 SUPERFAMILY SSF52540 50 174 2.1E-13 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14365 f8abfb72b9671e486088f25f6b988981 353 Gene3D G3DSA:3.40.50.300 24 175 1.0E-15 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28325 9c46ada446e9aa287ad3214577280b08 457 PANTHER PTHR34219 253 448 7.1E-178 T 13-09-2016 THL1_RS28325 9c46ada446e9aa287ad3214577280b08 457 PANTHER PTHR34219 3 222 7.1E-178 T 13-09-2016 THL1_RS28325 9c46ada446e9aa287ad3214577280b08 457 Pfam PF03413 Peptidase propeptide and YPEB domain 61 117 0.0058 T 13-09-2016 IPR025711 PepSY domain THL1_RS28325 9c46ada446e9aa287ad3214577280b08 457 Pfam PF03413 Peptidase propeptide and YPEB domain 287 341 0.0041 T 13-09-2016 IPR025711 PepSY domain THL1_RS28325 9c46ada446e9aa287ad3214577280b08 457 PANTHER PTHR34219:SF2 253 448 7.1E-178 T 13-09-2016 THL1_RS28325 9c46ada446e9aa287ad3214577280b08 457 PANTHER PTHR34219:SF2 3 222 7.1E-178 T 13-09-2016 THL1_RS28325 9c46ada446e9aa287ad3214577280b08 457 Pfam PF03929 PepSY-associated TM region 13 396 5.3E-64 T 13-09-2016 IPR005625 PepSY-associated TM protein THL1_RS23695 9d34fccf89a40b59de66d96ecea08e83 235 PRINTS PR01021 OMPA domain signature 153 168 9.6E-12 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS23695 9d34fccf89a40b59de66d96ecea08e83 235 PRINTS PR01021 OMPA domain signature 123 145 9.6E-12 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS23695 9d34fccf89a40b59de66d96ecea08e83 235 PRINTS PR01021 OMPA domain signature 168 184 9.6E-12 T 13-09-2016 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THL1_RS23695 9d34fccf89a40b59de66d96ecea08e83 235 Pfam PF13488 Glycine zipper 47 92 6.0E-10 T 13-09-2016 THL1_RS23695 9d34fccf89a40b59de66d96ecea08e83 235 Pfam PF00691 OmpA family 122 217 3.8E-22 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS23695 9d34fccf89a40b59de66d96ecea08e83 235 PANTHER PTHR30128 41 226 1.0E-53 T 13-09-2016 THL1_RS23695 9d34fccf89a40b59de66d96ecea08e83 235 SUPERFAMILY SSF103088 110 226 2.22E-38 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS23695 9d34fccf89a40b59de66d96ecea08e83 235 Gene3D G3DSA:3.30.1330.60 102 223 2.4E-40 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS07425 df6fda4bc5e4e2945c2d3f1ac5df7961 438 Pfam PF07804 HipA-like C-terminal domain 265 355 1.9E-11 T 13-09-2016 IPR012893 HipA-like, C-terminal THL1_RS07425 df6fda4bc5e4e2945c2d3f1ac5df7961 438 Pfam PF07805 HipA-like N-terminal domain 167 256 5.4E-11 T 13-09-2016 IPR012894 HipA, N-terminal subdomain 2 THL1_RS07425 df6fda4bc5e4e2945c2d3f1ac5df7961 438 PIRSF PIRSF028135 3 438 3.1E-111 T 13-09-2016 IPR016869 Uncharacterised conserved protein UCP028135, HipA-like THL1_RS22775 402465ff5181073bca071288c8fc95e8 585 Gene3D G3DSA:3.30.300.30 454 571 4.6E-7 T 13-09-2016 THL1_RS22775 402465ff5181073bca071288c8fc95e8 585 PANTHER PTHR24096 12 585 5.2E-156 T 13-09-2016 THL1_RS22775 402465ff5181073bca071288c8fc95e8 585 Pfam PF00501 AMP-binding enzyme 18 456 1.9E-89 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS22775 402465ff5181073bca071288c8fc95e8 585 ProSitePatterns PS00455 Putative AMP-binding domain signature. 179 190 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS22775 402465ff5181073bca071288c8fc95e8 585 Gene3D G3DSA:2.30.38.10 391 450 8.5E-23 T 13-09-2016 THL1_RS22775 402465ff5181073bca071288c8fc95e8 585 Gene3D G3DSA:3.40.50.980 185 274 5.6E-24 T 13-09-2016 THL1_RS22775 402465ff5181073bca071288c8fc95e8 585 Gene3D G3DSA:3.40.50.980 323 385 5.6E-24 T 13-09-2016 THL1_RS22775 402465ff5181073bca071288c8fc95e8 585 SUPERFAMILY SSF56801 6 279 7.72E-118 T 13-09-2016 THL1_RS22775 402465ff5181073bca071288c8fc95e8 585 SUPERFAMILY SSF56801 326 585 7.72E-118 T 13-09-2016 THL1_RS22775 402465ff5181073bca071288c8fc95e8 585 Gene3D G3DSA:3.40.50.980 13 184 6.8E-28 T 13-09-2016 THL1_RS10395 7b8fd0c090ea90186b3cc0371bcef33f 443 Pfam PF01966 HD domain 61 127 3.0E-8 T 13-09-2016 IPR006674 HD domain THL1_RS10395 7b8fd0c090ea90186b3cc0371bcef33f 443 Gene3D G3DSA:1.10.3210.10 3 112 1.2E-65 T 13-09-2016 IPR006674 HD domain THL1_RS10395 7b8fd0c090ea90186b3cc0371bcef33f 443 Gene3D G3DSA:1.10.3210.10 149 244 1.2E-65 T 13-09-2016 IPR006674 HD domain THL1_RS10395 7b8fd0c090ea90186b3cc0371bcef33f 443 PANTHER PTHR11373 1 132 3.5E-81 T 13-09-2016 THL1_RS10395 7b8fd0c090ea90186b3cc0371bcef33f 443 PANTHER PTHR11373 148 185 3.5E-81 T 13-09-2016 THL1_RS10395 7b8fd0c090ea90186b3cc0371bcef33f 443 PANTHER PTHR11373:SF29 1 132 3.5E-81 T 13-09-2016 THL1_RS10395 7b8fd0c090ea90186b3cc0371bcef33f 443 PANTHER PTHR11373:SF29 148 185 3.5E-81 T 13-09-2016 THL1_RS10395 7b8fd0c090ea90186b3cc0371bcef33f 443 Gene3D G3DSA:1.10.3410.10 245 351 2.2E-36 T 13-09-2016 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain THL1_RS10395 7b8fd0c090ea90186b3cc0371bcef33f 443 SMART SM00471 57 255 4.0E-9 T 13-09-2016 IPR003607 HD/PDEase domain THL1_RS10395 7b8fd0c090ea90186b3cc0371bcef33f 443 Gene3D G3DSA:1.10.3550.10 113 146 1.6E-32 T 13-09-2016 IPR027432 Deoxyguanosinetriphosphate triphosphohydrolase, C-terminal domain THL1_RS10395 7b8fd0c090ea90186b3cc0371bcef33f 443 Gene3D G3DSA:1.10.3550.10 352 440 1.6E-32 T 13-09-2016 IPR027432 Deoxyguanosinetriphosphate triphosphohydrolase, C-terminal domain THL1_RS10395 7b8fd0c090ea90186b3cc0371bcef33f 443 SUPERFAMILY SSF109604 21 187 3.66E-64 T 13-09-2016 THL1_RS10395 7b8fd0c090ea90186b3cc0371bcef33f 443 SUPERFAMILY SSF109604 224 434 3.66E-64 T 13-09-2016 THL1_RS10395 7b8fd0c090ea90186b3cc0371bcef33f 443 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 24 436 8.5E-96 T 13-09-2016 IPR006261 Deoxyguanosinetriphosphate triphosphohydrolase GO:0000287|GO:0008832|GO:0046039 THL1_RS16955 c43ba1348c29b1e5b302fba96af8ea04 423 Gene3D G3DSA:2.40.160.10 31 423 2.7E-140 T 13-09-2016 IPR023614 Porin domain THL1_RS16955 c43ba1348c29b1e5b302fba96af8ea04 423 Pfam PF03573 outer membrane porin, OprD family 26 421 7.4E-141 T 13-09-2016 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 THL1_RS16955 c43ba1348c29b1e5b302fba96af8ea04 423 SUPERFAMILY SSF56935 254 368 2.5E-5 T 13-09-2016 THL1_RS16955 c43ba1348c29b1e5b302fba96af8ea04 423 PANTHER PTHR34596 15 423 4.9E-145 T 13-09-2016 THL1_RS25880 09b2abc8c676bed65f6e12009488af00 155 SUPERFAMILY SSF52540 28 127 4.48E-24 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25880 09b2abc8c676bed65f6e12009488af00 155 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 10 138 3.2E-49 T 13-09-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 THL1_RS25880 09b2abc8c676bed65f6e12009488af00 155 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 11 130 1.3E-40 T 13-09-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 THL1_RS25880 09b2abc8c676bed65f6e12009488af00 155 Gene3D G3DSA:3.40.50.300 7 151 1.8E-49 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25880 09b2abc8c676bed65f6e12009488af00 155 PANTHER PTHR33540 3 152 6.9E-51 T 13-09-2016 THL1_RS20275 7ed3aade5ecc447bfc854ded62ee7fca 359 PANTHER PTHR30294 1 357 1.7E-101 T 13-09-2016 THL1_RS20275 7ed3aade5ecc447bfc854ded62ee7fca 359 PANTHER PTHR30294:SF12 1 357 1.7E-101 T 13-09-2016 THL1_RS20275 7ed3aade5ecc447bfc854ded62ee7fca 359 PRINTS PR00164 ABC-2 type transport system membrane protein signature 244 268 1.1E-5 T 13-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THL1_RS20275 7ed3aade5ecc447bfc854ded62ee7fca 359 PRINTS PR00164 ABC-2 type transport system membrane protein signature 281 300 1.1E-5 T 13-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THL1_RS20275 7ed3aade5ecc447bfc854ded62ee7fca 359 PRINTS PR00164 ABC-2 type transport system membrane protein signature 301 320 1.1E-5 T 13-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THL1_RS20275 7ed3aade5ecc447bfc854ded62ee7fca 359 Pfam PF12698 ABC-2 family transporter protein 24 351 2.2E-43 T 13-09-2016 THL1_RS00845 03b1fb0b2cd51aeb011fb06719da89ea 249 PANTHER PTHR11751:SF333 125 148 5.8E-28 T 13-09-2016 THL1_RS00845 03b1fb0b2cd51aeb011fb06719da89ea 249 PANTHER PTHR11751:SF333 10 78 5.8E-28 T 13-09-2016 THL1_RS00845 03b1fb0b2cd51aeb011fb06719da89ea 249 Gene3D G3DSA:3.40.1410.10 72 243 2.2E-52 T 13-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain THL1_RS00845 03b1fb0b2cd51aeb011fb06719da89ea 249 Gene3D G3DSA:1.10.10.10 8 71 7.1E-27 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00845 03b1fb0b2cd51aeb011fb06719da89ea 249 Pfam PF07702 UTRA domain 97 236 8.3E-40 T 13-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 THL1_RS00845 03b1fb0b2cd51aeb011fb06719da89ea 249 SUPERFAMILY SSF64288 63 243 8.64E-50 T 13-09-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain THL1_RS00845 03b1fb0b2cd51aeb011fb06719da89ea 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 75 3.4E-20 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS00845 03b1fb0b2cd51aeb011fb06719da89ea 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 7.1E-10 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS00845 03b1fb0b2cd51aeb011fb06719da89ea 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 7.1E-10 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS00845 03b1fb0b2cd51aeb011fb06719da89ea 249 PANTHER PTHR11751 125 148 5.8E-28 T 13-09-2016 THL1_RS00845 03b1fb0b2cd51aeb011fb06719da89ea 249 PANTHER PTHR11751 10 78 5.8E-28 T 13-09-2016 THL1_RS00845 03b1fb0b2cd51aeb011fb06719da89ea 249 SMART SM00345 16 75 6.8E-18 T 13-09-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 THL1_RS00845 03b1fb0b2cd51aeb011fb06719da89ea 249 SMART SM00866 96 236 2.5E-36 T 13-09-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 THL1_RS00845 03b1fb0b2cd51aeb011fb06719da89ea 249 SUPERFAMILY SSF46785 7 79 1.32E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08445 34f0d78eb1cc7eb9916ca517da57955b 545 PANTHER PTHR10617 73 391 1.3E-166 T 13-09-2016 THL1_RS08445 34f0d78eb1cc7eb9916ca517da57955b 545 PANTHER PTHR10617 471 536 1.3E-166 T 13-09-2016 THL1_RS08445 34f0d78eb1cc7eb9916ca517da57955b 545 SUPERFAMILY SSF51905 101 287 3.56E-36 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS08445 34f0d78eb1cc7eb9916ca517da57955b 545 SUPERFAMILY SSF51905 478 531 3.56E-36 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS08445 34f0d78eb1cc7eb9916ca517da57955b 545 Gene3D G3DSA:3.50.50.60 101 289 1.6E-34 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS08445 34f0d78eb1cc7eb9916ca517da57955b 545 Gene3D G3DSA:3.50.50.60 464 533 1.6E-34 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS08445 34f0d78eb1cc7eb9916ca517da57955b 545 PANTHER PTHR10617:SF52 73 391 1.3E-166 T 13-09-2016 THL1_RS08445 34f0d78eb1cc7eb9916ca517da57955b 545 PANTHER PTHR10617:SF52 471 536 1.3E-166 T 13-09-2016 THL1_RS08445 34f0d78eb1cc7eb9916ca517da57955b 545 PIRSF PIRSF038984 1 537 1.2E-240 T 13-09-2016 IPR028348 FAD dependent protein THL1_RS23000 b14e217395244ef55f5133b2bc0c0595 145 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 97 8.5E-22 T 13-09-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 THL1_RS23000 b14e217395244ef55f5133b2bc0c0595 145 PANTHER PTHR11079 1 143 2.3E-67 T 13-09-2016 THL1_RS23000 b14e217395244ef55f5133b2bc0c0595 145 SUPERFAMILY SSF53927 3 143 6.19E-40 T 13-09-2016 IPR016193 Cytidine deaminase-like GO:0003824 THL1_RS23000 b14e217395244ef55f5133b2bc0c0595 145 Gene3D G3DSA:3.40.140.10 3 134 2.9E-39 T 13-09-2016 THL1_RS23000 b14e217395244ef55f5133b2bc0c0595 145 PANTHER PTHR11079:SF63 1 143 2.3E-67 T 13-09-2016 THL1_RS25535 3d3b9bfbca52caa6795b6ea5f2efb08a 421 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 31 404 1.3E-180 T 13-09-2016 IPR017777 ABC transporter, urea, substrate-binding, UrtA THL1_RS25535 3d3b9bfbca52caa6795b6ea5f2efb08a 421 PANTHER PTHR30483 1 420 2.9E-230 T 13-09-2016 THL1_RS25535 3d3b9bfbca52caa6795b6ea5f2efb08a 421 PANTHER PTHR30483:SF8 1 420 2.9E-230 T 13-09-2016 THL1_RS25535 3d3b9bfbca52caa6795b6ea5f2efb08a 421 SUPERFAMILY SSF53822 30 408 4.19E-94 T 13-09-2016 IPR028082 Periplasmic binding protein-like I THL1_RS25535 3d3b9bfbca52caa6795b6ea5f2efb08a 421 Gene3D G3DSA:3.40.50.2300 146 345 5.3E-76 T 13-09-2016 THL1_RS25535 3d3b9bfbca52caa6795b6ea5f2efb08a 421 Pfam PF13433 Periplasmic binding protein domain 31 407 4.1E-175 T 13-09-2016 THL1_RS25535 3d3b9bfbca52caa6795b6ea5f2efb08a 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 31 47 2.0E-5 T 13-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THL1_RS25535 3d3b9bfbca52caa6795b6ea5f2efb08a 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 290 303 2.0E-5 T 13-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THL1_RS25535 3d3b9bfbca52caa6795b6ea5f2efb08a 421 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 53 69 2.0E-5 T 13-09-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 THL1_RS04625 b963ef3a5f89dbc63677f42fe34d1396 402 Pfam PF05977 Transmembrane secretion effector 11 389 8.7E-38 T 13-09-2016 IPR010290 Transmembrane secretion effector THL1_RS04625 b963ef3a5f89dbc63677f42fe34d1396 402 PANTHER PTHR23513:SF9 1 402 8.2E-146 T 13-09-2016 THL1_RS04625 b963ef3a5f89dbc63677f42fe34d1396 402 Gene3D G3DSA:1.20.1250.20 226 396 2.0E-10 T 13-09-2016 THL1_RS04625 b963ef3a5f89dbc63677f42fe34d1396 402 Gene3D G3DSA:1.20.1250.20 10 194 4.4E-21 T 13-09-2016 THL1_RS04625 b963ef3a5f89dbc63677f42fe34d1396 402 PANTHER PTHR23513 1 402 8.2E-146 T 13-09-2016 THL1_RS04625 b963ef3a5f89dbc63677f42fe34d1396 402 SUPERFAMILY SSF103473 1 399 2.88E-43 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS06855 e70590fa7f93ab04266a6a1eb6efa5c0 270 SUPERFAMILY SSF51735 4 258 8.28E-65 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS06855 e70590fa7f93ab04266a6a1eb6efa5c0 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 7.2E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06855 e70590fa7f93ab04266a6a1eb6efa5c0 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 7.2E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06855 e70590fa7f93ab04266a6a1eb6efa5c0 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 7.2E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06855 e70590fa7f93ab04266a6a1eb6efa5c0 270 PANTHER PTHR24322 7 134 3.1E-52 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06855 e70590fa7f93ab04266a6a1eb6efa5c0 270 PANTHER PTHR24322 150 182 3.1E-52 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06855 e70590fa7f93ab04266a6a1eb6efa5c0 270 Gene3D G3DSA:3.40.50.720 4 228 3.0E-64 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS06855 e70590fa7f93ab04266a6a1eb6efa5c0 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 4.6E-27 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06855 e70590fa7f93ab04266a6a1eb6efa5c0 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 4.6E-27 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06855 e70590fa7f93ab04266a6a1eb6efa5c0 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.6E-27 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06855 e70590fa7f93ab04266a6a1eb6efa5c0 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 4.6E-27 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06855 e70590fa7f93ab04266a6a1eb6efa5c0 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 4.6E-27 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS06855 e70590fa7f93ab04266a6a1eb6efa5c0 270 Pfam PF00106 short chain dehydrogenase 4 190 4.9E-51 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS25605 d270e6bfe1e01c8bb98dade5bd088e66 148 Pfam PF09335 SNARE associated Golgi protein 27 140 5.7E-14 T 13-09-2016 IPR032816 SNARE associated Golgi protein THL1_RS25605 d270e6bfe1e01c8bb98dade5bd088e66 148 PANTHER PTHR30353 2 143 5.4E-55 T 13-09-2016 IPR032818 DedA family THL1_RS25605 d270e6bfe1e01c8bb98dade5bd088e66 148 PANTHER PTHR30353:SF12 2 143 5.4E-55 T 13-09-2016 THL1_RS25605 d270e6bfe1e01c8bb98dade5bd088e66 148 ProDom PD085709 MEMBRANE RP436 UNCHARACTERIZED INTEGRAL PREDICTED TRANSMEMBRANE 10 116 0.001 T 13-09-2016 IPR020143 Uncharacterised protein family, RP436 THL1_RS24370 f98e4c6c8aee862acdd86b0d12df1948 472 Gene3D G3DSA:1.25.40.10 296 417 1.6E-8 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS20945 9bc6ff73a4d053dbb81df5b7eabca614 270 PANTHER PTHR11941:SF76 13 267 1.7E-65 T 13-09-2016 THL1_RS20945 9bc6ff73a4d053dbb81df5b7eabca614 270 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 269 3.9E-52 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS20945 9bc6ff73a4d053dbb81df5b7eabca614 270 PANTHER PTHR11941 13 267 1.7E-65 T 13-09-2016 THL1_RS20945 9bc6ff73a4d053dbb81df5b7eabca614 270 SUPERFAMILY SSF52096 11 269 4.4E-70 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20945 9bc6ff73a4d053dbb81df5b7eabca614 270 Gene3D G3DSA:1.10.12.10 212 269 5.0E-15 T 13-09-2016 IPR014748 Crontonase, C-terminal THL1_RS20945 9bc6ff73a4d053dbb81df5b7eabca614 270 Gene3D G3DSA:3.90.226.10 13 211 3.1E-53 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS21635 a40a33e6e9378b79429c8d11941e73e2 495 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 260 448 3.1E-57 T 13-09-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 THL1_RS21635 a40a33e6e9378b79429c8d11941e73e2 495 PANTHER PTHR10196:SF44 1 493 0.0 T 13-09-2016 THL1_RS21635 a40a33e6e9378b79429c8d11941e73e2 495 Gene3D G3DSA:3.30.420.40 252 492 8.7E-97 T 13-09-2016 THL1_RS21635 a40a33e6e9378b79429c8d11941e73e2 495 Gene3D G3DSA:3.30.420.40 2 251 8.6E-102 T 13-09-2016 THL1_RS21635 a40a33e6e9378b79429c8d11941e73e2 495 SUPERFAMILY SSF53067 4 253 7.77E-96 T 13-09-2016 THL1_RS21635 a40a33e6e9378b79429c8d11941e73e2 495 SUPERFAMILY SSF53067 253 492 8.09E-79 T 13-09-2016 THL1_RS21635 a40a33e6e9378b79429c8d11941e73e2 495 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 250 1.5E-74 T 13-09-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 THL1_RS21635 a40a33e6e9378b79429c8d11941e73e2 495 PIRSF PIRSF000538 2 495 6.7E-172 T 13-09-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 THL1_RS21635 a40a33e6e9378b79429c8d11941e73e2 495 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 134 146 - T 13-09-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 THL1_RS21635 a40a33e6e9378b79429c8d11941e73e2 495 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 491 1.6E-219 T 13-09-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 THL1_RS21635 a40a33e6e9378b79429c8d11941e73e2 495 PANTHER PTHR10196 1 493 0.0 T 13-09-2016 THL1_RS21635 a40a33e6e9378b79429c8d11941e73e2 495 Hamap MF_00186 Glycerol kinase [glpK]. 2 495 55.081 T 13-09-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 THL1_RS00375 3c8f010408b0c552760b6ab54a074334 96 PANTHER PTHR40942:SF2 1 96 6.8E-57 T 13-09-2016 THL1_RS00375 3c8f010408b0c552760b6ab54a074334 96 Gene3D G3DSA:1.10.760.10 19 95 8.0E-30 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS00375 3c8f010408b0c552760b6ab54a074334 96 PANTHER PTHR40942 1 96 6.8E-57 T 13-09-2016 THL1_RS00375 3c8f010408b0c552760b6ab54a074334 96 PRINTS PR00607 Class IE cytochrome C signature 41 51 1.0E-9 T 13-09-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 THL1_RS00375 3c8f010408b0c552760b6ab54a074334 96 PRINTS PR00607 Class IE cytochrome C signature 30 41 1.0E-9 T 13-09-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 THL1_RS00375 3c8f010408b0c552760b6ab54a074334 96 PRINTS PR00607 Class IE cytochrome C signature 69 81 1.0E-9 T 13-09-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 THL1_RS00375 3c8f010408b0c552760b6ab54a074334 96 PRINTS PR00607 Class IE cytochrome C signature 84 95 1.0E-9 T 13-09-2016 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 THL1_RS00375 3c8f010408b0c552760b6ab54a074334 96 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 19 94 1.1E-14 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS00375 3c8f010408b0c552760b6ab54a074334 96 SUPERFAMILY SSF46626 20 95 6.4E-18 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS07190 33acfa10ffb98a1d40aa0933e00e4444 161 Gene3D G3DSA:2.40.50.180 53 91 1.3E-10 T 13-09-2016 THL1_RS07190 33acfa10ffb98a1d40aa0933e00e4444 161 PANTHER PTHR22617 14 161 9.1E-50 T 13-09-2016 THL1_RS07190 33acfa10ffb98a1d40aa0933e00e4444 161 SMART SM00260 11 148 1.5E-41 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS07190 33acfa10ffb98a1d40aa0933e00e4444 161 SUPERFAMILY SSF50341 12 153 1.96E-39 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS07190 33acfa10ffb98a1d40aa0933e00e4444 161 Pfam PF01584 CheW-like domain 15 151 1.5E-35 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS07190 33acfa10ffb98a1d40aa0933e00e4444 161 Gene3D G3DSA:2.30.30.40 92 141 6.2E-5 T 13-09-2016 THL1_RS02330 c1aaa82619eaa82ab04323d223d7c39d 398 PANTHER PTHR32027 4 395 1.8E-102 T 13-09-2016 THL1_RS02330 c1aaa82619eaa82ab04323d223d7c39d 398 SUPERFAMILY SSF51556 54 359 1.09E-75 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS02330 c1aaa82619eaa82ab04323d223d7c39d 398 Gene3D G3DSA:3.20.20.140 65 349 3.0E-97 T 13-09-2016 THL1_RS02330 c1aaa82619eaa82ab04323d223d7c39d 398 Gene3D G3DSA:2.30.40.10 3 64 1.4E-7 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS02330 c1aaa82619eaa82ab04323d223d7c39d 398 Pfam PF07969 Amidohydrolase family 106 371 1.5E-20 T 13-09-2016 IPR013108 Amidohydrolase 3 THL1_RS02330 c1aaa82619eaa82ab04323d223d7c39d 398 PANTHER PTHR32027:SF9 4 395 1.8E-102 T 13-09-2016 THL1_RS20205 34bc282742a3326cf8eca01d31e69fda 144 PANTHER PTHR23089 7 139 6.9E-40 T 13-09-2016 IPR001310 Histidine triad (HIT) protein THL1_RS20205 34bc282742a3326cf8eca01d31e69fda 144 Pfam PF01230 HIT domain 18 115 2.0E-25 T 13-09-2016 IPR001310 Histidine triad (HIT) protein THL1_RS20205 34bc282742a3326cf8eca01d31e69fda 144 Gene3D G3DSA:3.30.428.10 10 143 1.9E-35 T 13-09-2016 IPR011146 HIT-like domain GO:0003824 THL1_RS20205 34bc282742a3326cf8eca01d31e69fda 144 SUPERFAMILY SSF54197 6 143 5.88E-37 T 13-09-2016 IPR011146 HIT-like domain GO:0003824 THL1_RS20205 34bc282742a3326cf8eca01d31e69fda 144 PRINTS PR00332 Histidine triad family signature 101 111 1.5E-16 T 13-09-2016 IPR001310 Histidine triad (HIT) protein THL1_RS20205 34bc282742a3326cf8eca01d31e69fda 144 PRINTS PR00332 Histidine triad family signature 33 51 1.5E-16 T 13-09-2016 IPR001310 Histidine triad (HIT) protein THL1_RS20205 34bc282742a3326cf8eca01d31e69fda 144 PRINTS PR00332 Histidine triad family signature 12 28 1.5E-16 T 13-09-2016 IPR001310 Histidine triad (HIT) protein THL1_RS20205 34bc282742a3326cf8eca01d31e69fda 144 PANTHER PTHR23089:SF7 7 139 6.9E-40 T 13-09-2016 THL1_RS19050 b13dc3a151cdb292feef644f224e1ccb 114 PANTHER PTHR33271 36 114 2.3E-24 T 13-09-2016 THL1_RS19050 b13dc3a151cdb292feef644f224e1ccb 114 Pfam PF05899 Protein of unknown function (DUF861) 39 111 1.2E-25 T 13-09-2016 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 THL1_RS19050 b13dc3a151cdb292feef644f224e1ccb 114 Gene3D G3DSA:2.60.120.10 21 113 6.8E-34 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS19050 b13dc3a151cdb292feef644f224e1ccb 114 SUPERFAMILY SSF51182 21 113 1.69E-19 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS19390 c4ba7fad8e6d0fbc525a0498c6a39d6b 180 Pfam PF13511 Domain of unknown function (DUF4124) 10 67 6.5E-15 T 13-09-2016 IPR025392 Domain of unknown function DUF4124 THL1_RS18875 64320325f175df4c88ab97c2829e9c3d 460 PANTHER PTHR13932 1 455 1.0E-230 T 13-09-2016 THL1_RS18875 64320325f175df4c88ab97c2829e9c3d 460 SMART SM00729 53 276 6.9E-49 T 13-09-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 THL1_RS18875 64320325f175df4c88ab97c2829e9c3d 460 SUPERFAMILY SSF102114 6 448 3.01E-135 T 13-09-2016 THL1_RS18875 64320325f175df4c88ab97c2829e9c3d 460 PANTHER PTHR13932:SF6 1 455 1.0E-230 T 13-09-2016 THL1_RS18875 64320325f175df4c88ab97c2829e9c3d 460 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 6 460 6.3E-175 T 13-09-2016 IPR004558 Coproporphyrinogen III oxidase, oxygen-independent, HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.99.22|UniPathway: UPA00251 THL1_RS18875 64320325f175df4c88ab97c2829e9c3d 460 Gene3D G3DSA:3.80.30.20 54 285 3.3E-29 T 13-09-2016 IPR023404 Radical SAM, alpha/beta horseshoe THL1_RS18875 64320325f175df4c88ab97c2829e9c3d 460 PIRSF PIRSF000167 3 459 3.3E-169 T 13-09-2016 IPR004558 Coproporphyrinogen III oxidase, oxygen-independent, HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.99.22|UniPathway: UPA00251 THL1_RS18875 64320325f175df4c88ab97c2829e9c3d 460 Pfam PF06969 HemN C-terminal domain 368 435 2.2E-12 T 13-09-2016 IPR010723 HemN, C-terminal THL1_RS18875 64320325f175df4c88ab97c2829e9c3d 460 Pfam PF04055 Radical SAM superfamily 58 232 1.8E-18 T 13-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 THL1_RS28485 3bdd582f0137548822353166362f06ac 559 Pfam PF02096 60Kd inner membrane protein 370 548 2.0E-62 T 13-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THL1_RS28485 3bdd582f0137548822353166362f06ac 559 Pfam PF14849 YidC periplasmic domain 82 359 7.5E-87 T 13-09-2016 IPR028053 Membrane insertase YidC, N-terminal THL1_RS28485 3bdd582f0137548822353166362f06ac 559 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 369 548 2.0E-72 T 13-09-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal THL1_RS28485 3bdd582f0137548822353166362f06ac 559 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 4 368 9.1E-115 T 13-09-2016 IPR028053 Membrane insertase YidC, N-terminal THL1_RS28485 3bdd582f0137548822353166362f06ac 559 PANTHER PTHR12428:SF14 185 552 3.8E-133 T 13-09-2016 THL1_RS28485 3bdd582f0137548822353166362f06ac 559 PANTHER PTHR12428 185 552 3.8E-133 T 13-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THL1_RS28485 3bdd582f0137548822353166362f06ac 559 PRINTS PR00701 60kDa inner membrane protein signature 234 252 1.4E-98 T 13-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THL1_RS28485 3bdd582f0137548822353166362f06ac 559 PRINTS PR00701 60kDa inner membrane protein signature 478 500 1.4E-98 T 13-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THL1_RS28485 3bdd582f0137548822353166362f06ac 559 PRINTS PR00701 60kDa inner membrane protein signature 2 23 1.4E-98 T 13-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THL1_RS28485 3bdd582f0137548822353166362f06ac 559 PRINTS PR00701 60kDa inner membrane protein signature 178 198 1.4E-98 T 13-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THL1_RS28485 3bdd582f0137548822353166362f06ac 559 PRINTS PR00701 60kDa inner membrane protein signature 340 360 1.4E-98 T 13-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THL1_RS28485 3bdd582f0137548822353166362f06ac 559 PRINTS PR00701 60kDa inner membrane protein signature 431 454 1.4E-98 T 13-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THL1_RS28485 3bdd582f0137548822353166362f06ac 559 PRINTS PR00701 60kDa inner membrane protein signature 87 108 1.4E-98 T 13-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THL1_RS28485 3bdd582f0137548822353166362f06ac 559 PRINTS PR00701 60kDa inner membrane protein signature 267 282 1.4E-98 T 13-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THL1_RS28485 3bdd582f0137548822353166362f06ac 559 PRINTS PR00701 60kDa inner membrane protein signature 514 537 1.4E-98 T 13-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THL1_RS28485 3bdd582f0137548822353166362f06ac 559 PRINTS PR01900 YidC translocation/secretion protein signature 355 371 9.3E-29 T 13-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THL1_RS28485 3bdd582f0137548822353166362f06ac 559 PRINTS PR01900 YidC translocation/secretion protein signature 503 527 9.3E-29 T 13-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THL1_RS28485 3bdd582f0137548822353166362f06ac 559 PRINTS PR01900 YidC translocation/secretion protein signature 484 499 9.3E-29 T 13-09-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 THL1_RS28485 3bdd582f0137548822353166362f06ac 559 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 550 25.477 T 13-09-2016 IPR019998 Membrane insertase YidC GO:0016021|GO:0051205 THL1_RS23810 2d4bfc61d4ebe22683f479bd341149c2 204 PANTHER PTHR13604 3 203 6.6E-43 T 13-09-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS23810 2d4bfc61d4ebe22683f479bd341149c2 204 SUPERFAMILY SSF143081 3 203 2.22E-43 T 13-09-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS23810 2d4bfc61d4ebe22683f479bd341149c2 204 Gene3D G3DSA:3.90.1680.10 21 203 2.5E-39 T 13-09-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS23810 2d4bfc61d4ebe22683f479bd341149c2 204 Pfam PF02586 SOS response associated peptidase (SRAP) 1 191 6.2E-33 T 13-09-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS16405 57257ca24ff43c3641a49af185c61af5 1103 Pfam PF13558 Putative exonuclease SbcCD, C subunit 959 1047 2.2E-15 T 13-09-2016 THL1_RS16405 57257ca24ff43c3641a49af185c61af5 1103 SUPERFAMILY SSF52540 23 139 3.68E-10 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16405 57257ca24ff43c3641a49af185c61af5 1103 SUPERFAMILY SSF52540 301 468 3.68E-10 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16405 57257ca24ff43c3641a49af185c61af5 1103 SUPERFAMILY SSF52540 209 220 3.68E-10 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16405 57257ca24ff43c3641a49af185c61af5 1103 Pfam PF13555 P-loop containing region of AAA domain 22 78 6.2E-18 T 13-09-2016 THL1_RS16405 57257ca24ff43c3641a49af185c61af5 1103 Gene3D G3DSA:3.40.1140.10 24 235 6.4E-14 T 13-09-2016 THL1_RS27395 2649cfa672a4d69ddf541712885022e9 179 Pfam PF00924 Mechanosensitive ion channel 59 176 1.7E-12 T 13-09-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 THL1_RS27395 2649cfa672a4d69ddf541712885022e9 179 Gene3D G3DSA:2.30.30.60 119 176 8.4E-12 T 13-09-2016 THL1_RS27395 2649cfa672a4d69ddf541712885022e9 179 PANTHER PTHR30221:SF8 1 179 6.6E-59 T 13-09-2016 THL1_RS27395 2649cfa672a4d69ddf541712885022e9 179 PANTHER PTHR30221 1 179 6.6E-59 T 13-09-2016 THL1_RS27395 2649cfa672a4d69ddf541712885022e9 179 SUPERFAMILY SSF50182 104 178 2.58E-10 T 13-09-2016 IPR010920 LSM domain THL1_RS18095 088d7de0850ef4dde8ce2ffe27d97e30 228 SUPERFAMILY SSF49899 2 227 1.03E-63 T 13-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain THL1_RS18095 088d7de0850ef4dde8ce2ffe27d97e30 228 Gene3D G3DSA:2.60.120.200 2 227 1.1E-52 T 13-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain THL1_RS18095 088d7de0850ef4dde8ce2ffe27d97e30 228 Pfam PF08787 Alginate lyase 2 224 1.2E-53 T 13-09-2016 IPR014895 Alginate lyase 2 THL1_RS07335 f02d93ddae6c6b4ef99c1a26985e179e 413 PANTHER PTHR13847 22 397 1.0E-62 T 13-09-2016 THL1_RS07335 f02d93ddae6c6b4ef99c1a26985e179e 413 SUPERFAMILY SSF54373 260 340 1.05E-8 T 13-09-2016 THL1_RS07335 f02d93ddae6c6b4ef99c1a26985e179e 413 Pfam PF01266 FAD dependent oxidoreductase 31 378 1.8E-56 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS07335 f02d93ddae6c6b4ef99c1a26985e179e 413 Gene3D G3DSA:3.50.50.60 23 108 3.9E-50 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07335 f02d93ddae6c6b4ef99c1a26985e179e 413 Gene3D G3DSA:3.50.50.60 340 399 3.9E-50 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07335 f02d93ddae6c6b4ef99c1a26985e179e 413 Gene3D G3DSA:3.50.50.60 171 249 3.9E-50 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07335 f02d93ddae6c6b4ef99c1a26985e179e 413 SUPERFAMILY SSF51905 340 401 6.48E-52 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07335 f02d93ddae6c6b4ef99c1a26985e179e 413 SUPERFAMILY SSF51905 30 250 6.48E-52 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07335 f02d93ddae6c6b4ef99c1a26985e179e 413 Gene3D G3DSA:3.30.9.10 113 170 4.5E-18 T 13-09-2016 THL1_RS07335 f02d93ddae6c6b4ef99c1a26985e179e 413 Gene3D G3DSA:3.30.9.10 250 339 4.5E-18 T 13-09-2016 THL1_RS15435 1fa17cda6e17435fb72e69892692f7f5 153 SUPERFAMILY SSF53927 2 131 7.97E-37 T 13-09-2016 IPR016193 Cytidine deaminase-like GO:0003824 THL1_RS15435 1fa17cda6e17435fb72e69892692f7f5 153 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 100 6.2E-20 T 13-09-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 THL1_RS15435 1fa17cda6e17435fb72e69892692f7f5 153 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 89 - T 13-09-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 THL1_RS15435 1fa17cda6e17435fb72e69892692f7f5 153 Gene3D G3DSA:3.40.140.10 2 134 1.7E-40 T 13-09-2016 THL1_RS15435 1fa17cda6e17435fb72e69892692f7f5 153 PANTHER PTHR11079 3 103 4.7E-26 T 13-09-2016 THL1_RS17200 40a5112aa15d54270048773ec92335ab 347 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 308 323 1.5E-6 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS17200 40a5112aa15d54270048773ec92335ab 347 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 323 339 1.5E-6 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS17200 40a5112aa15d54270048773ec92335ab 347 PANTHER PTHR11019:SF52 191 347 5.1E-25 T 13-09-2016 THL1_RS17200 40a5112aa15d54270048773ec92335ab 347 SUPERFAMILY SSF46689 293 341 1.84E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17200 40a5112aa15d54270048773ec92335ab 347 Pfam PF12833 Helix-turn-helix domain 264 340 8.4E-16 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS17200 40a5112aa15d54270048773ec92335ab 347 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 35 213 4.8E-31 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS17200 40a5112aa15d54270048773ec92335ab 347 Gene3D G3DSA:1.10.10.60 292 341 1.7E-16 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS17200 40a5112aa15d54270048773ec92335ab 347 PANTHER PTHR11019 191 347 5.1E-25 T 13-09-2016 THL1_RS17200 40a5112aa15d54270048773ec92335ab 347 SMART SM00342 256 339 5.4E-18 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS01080 a45fb4b260509aa7e9dc4f49522ec5ef 341 Gene3D G3DSA:3.30.1370.60 80 282 4.5E-79 T 13-09-2016 THL1_RS01080 a45fb4b260509aa7e9dc4f49522ec5ef 341 PANTHER PTHR11091 6 341 6.6E-80 T 13-09-2016 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS01080 a45fb4b260509aa7e9dc4f49522ec5ef 341 SUPERFAMILY SSF89733 9 340 4.19E-102 T 13-09-2016 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS01080 a45fb4b260509aa7e9dc4f49522ec5ef 341 Pfam PF02615 Malate/L-lactate dehydrogenase 12 335 5.7E-106 T 13-09-2016 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS01080 a45fb4b260509aa7e9dc4f49522ec5ef 341 Gene3D G3DSA:1.10.1530.10 11 79 5.5E-25 T 13-09-2016 THL1_RS08295 088a05ac5ee58f7d7adc0f88a7ab1e5c 87 Pfam PF10976 Protein of unknown function (DUF2790) 8 85 2.4E-29 T 13-09-2016 IPR021245 Protein of unknown function DUF2790 THL1_RS23600 1f44e9eedb313b3a580751945a6bf9f8 236 PANTHER PTHR24322 10 132 9.4E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23600 1f44e9eedb313b3a580751945a6bf9f8 236 PANTHER PTHR24322 148 182 9.4E-24 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23600 1f44e9eedb313b3a580751945a6bf9f8 236 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS23600 1f44e9eedb313b3a580751945a6bf9f8 236 Pfam PF00106 short chain dehydrogenase 8 180 4.5E-25 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23600 1f44e9eedb313b3a580751945a6bf9f8 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 4.3E-9 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23600 1f44e9eedb313b3a580751945a6bf9f8 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 4.3E-9 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23600 1f44e9eedb313b3a580751945a6bf9f8 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.3E-9 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS23600 1f44e9eedb313b3a580751945a6bf9f8 236 Gene3D G3DSA:3.40.50.720 8 235 1.2E-48 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23600 1f44e9eedb313b3a580751945a6bf9f8 236 SUPERFAMILY SSF51735 8 235 6.46E-39 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18950 76022128acaa61ab6dded57cd496f60b 294 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 193 3.6E-4 T 13-09-2016 THL1_RS18950 76022128acaa61ab6dded57cd496f60b 294 Pfam PF00106 short chain dehydrogenase 7 199 7.8E-51 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18950 76022128acaa61ab6dded57cd496f60b 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.3E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18950 76022128acaa61ab6dded57cd496f60b 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.3E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18950 76022128acaa61ab6dded57cd496f60b 294 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.3E-12 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18950 76022128acaa61ab6dded57cd496f60b 294 PANTHER PTHR24322 11 139 1.7E-66 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18950 76022128acaa61ab6dded57cd496f60b 294 PANTHER PTHR24322 155 189 1.7E-66 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18950 76022128acaa61ab6dded57cd496f60b 294 PANTHER PTHR24322:SF365 11 139 1.7E-66 T 13-09-2016 THL1_RS18950 76022128acaa61ab6dded57cd496f60b 294 PANTHER PTHR24322:SF365 155 189 1.7E-66 T 13-09-2016 THL1_RS18950 76022128acaa61ab6dded57cd496f60b 294 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS18950 76022128acaa61ab6dded57cd496f60b 294 Gene3D G3DSA:3.40.50.720 6 270 1.3E-70 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18950 76022128acaa61ab6dded57cd496f60b 294 SUPERFAMILY SSF51735 1 277 1.77E-70 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18950 76022128acaa61ab6dded57cd496f60b 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.0E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18950 76022128acaa61ab6dded57cd496f60b 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.0E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18950 76022128acaa61ab6dded57cd496f60b 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 4.0E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18950 76022128acaa61ab6dded57cd496f60b 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.0E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18950 76022128acaa61ab6dded57cd496f60b 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 4.0E-26 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS16365 0f754d4b863e8ba2e70643ff8bec3e58 99 Pfam PF07238 PilZ domain 10 98 2.2E-12 T 13-09-2016 IPR009875 PilZ domain GO:0035438 THL1_RS16365 0f754d4b863e8ba2e70643ff8bec3e58 99 SUPERFAMILY SSF141371 7 97 5.89E-16 T 13-09-2016 THL1_RS16365 0f754d4b863e8ba2e70643ff8bec3e58 99 Gene3D G3DSA:2.40.10.220 7 95 1.3E-7 T 13-09-2016 THL1_RS20145 142db41142517be1297d4cff891bcc5a 147 PANTHER PTHR35174 19 126 1.9E-20 T 13-09-2016 THL1_RS20145 142db41142517be1297d4cff891bcc5a 147 PANTHER PTHR35174:SF3 19 126 1.9E-20 T 13-09-2016 THL1_RS20145 142db41142517be1297d4cff891bcc5a 147 Gene3D G3DSA:3.10.450.50 9 131 1.1E-27 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS20145 142db41142517be1297d4cff891bcc5a 147 Pfam PF13474 SnoaL-like domain 14 134 1.5E-17 T 13-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain THL1_RS20145 142db41142517be1297d4cff891bcc5a 147 SUPERFAMILY SSF54427 13 131 3.07E-28 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS09515 d58e6c307c2c331d391622e8d79df77a 277 Pfam PF13478 XdhC Rossmann domain 106 247 1.8E-37 T 13-09-2016 IPR027051 XdhC Rossmann domain THL1_RS09515 d58e6c307c2c331d391622e8d79df77a 277 PANTHER PTHR30388:SF5 1 274 3.2E-133 T 13-09-2016 THL1_RS09515 d58e6c307c2c331d391622e8d79df77a 277 Pfam PF02625 XdhC and CoxI family 11 70 9.8E-19 T 13-09-2016 IPR003777 XdhC- CoxI THL1_RS09515 d58e6c307c2c331d391622e8d79df77a 277 SUPERFAMILY SSF51735 97 188 2.77E-11 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS09515 d58e6c307c2c331d391622e8d79df77a 277 PANTHER PTHR30388 1 274 3.2E-133 T 13-09-2016 THL1_RS09515 d58e6c307c2c331d391622e8d79df77a 277 Gene3D G3DSA:3.40.50.720 102 187 1.5E-5 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS09515 d58e6c307c2c331d391622e8d79df77a 277 TIGRFAM TIGR02964 xanthine_xdhC: xanthine dehydrogenase accessory protein XdhC 18 247 1.0E-100 T 13-09-2016 IPR014308 Xanthine dehydrogenase accessory protein XdhC THL1_RS02155 dc9ffecababb3ec2f2bd82c79d7c9e4a 242 SUPERFAMILY SSF53271 46 239 2.23E-36 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS02155 dc9ffecababb3ec2f2bd82c79d7c9e4a 242 Gene3D G3DSA:3.40.50.2020 59 238 1.8E-33 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS02155 dc9ffecababb3ec2f2bd82c79d7c9e4a 242 Pfam PF00156 Phosphoribosyl transferase domain 107 237 1.1E-7 T 13-09-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 THL1_RS02155 dc9ffecababb3ec2f2bd82c79d7c9e4a 242 PANTHER PTHR11907:SF9 4 241 2.3E-58 T 13-09-2016 THL1_RS02155 dc9ffecababb3ec2f2bd82c79d7c9e4a 242 PANTHER PTHR11907 4 241 2.3E-58 T 13-09-2016 THL1_RS19570 9b6ba4699aa9079c1f4c1360b12fa338 425 Pfam PF02120 Flagellar hook-length control protein FliK 294 371 2.5E-21 T 13-09-2016 IPR021136 Flagellar hook-length control protein-like, C-terminal THL1_RS19570 9b6ba4699aa9079c1f4c1360b12fa338 425 PANTHER PTHR37533:SF2 175 425 7.0E-47 T 13-09-2016 THL1_RS19570 9b6ba4699aa9079c1f4c1360b12fa338 425 PANTHER PTHR37533 175 425 7.0E-47 T 13-09-2016 THL1_RS10260 7963236877b1a9bd82c9dc7ee027687b 288 Pfam PF16733 Rhomboid N-terminal domain 1 68 3.1E-32 T 13-09-2016 IPR031976 Rhomboid protease, N-terminal THL1_RS10260 7963236877b1a9bd82c9dc7ee027687b 288 SUPERFAMILY SSF144091 88 278 1.05E-30 T 13-09-2016 THL1_RS10260 7963236877b1a9bd82c9dc7ee027687b 288 PANTHER PTHR22936:SF30 84 288 3.7E-44 T 13-09-2016 THL1_RS10260 7963236877b1a9bd82c9dc7ee027687b 288 Pfam PF01694 Rhomboid family 138 279 9.1E-26 T 13-09-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 THL1_RS10260 7963236877b1a9bd82c9dc7ee027687b 288 Gene3D G3DSA:1.20.1540.10 88 278 1.6E-26 T 13-09-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 THL1_RS10260 7963236877b1a9bd82c9dc7ee027687b 288 PANTHER PTHR22936 84 288 3.7E-44 T 13-09-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 THL1_RS03285 6fb7845b9c2492491293280373fbd3bc 218 PANTHER PTHR30614 1 218 6.2E-72 T 13-09-2016 THL1_RS03285 6fb7845b9c2492491293280373fbd3bc 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 214 9.5E-16 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS03285 6fb7845b9c2492491293280373fbd3bc 218 SUPERFAMILY SSF161098 12 200 2.62E-39 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS03285 6fb7845b9c2492491293280373fbd3bc 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 7.9E-24 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS03285 6fb7845b9c2492491293280373fbd3bc 218 Gene3D G3DSA:1.10.3720.10 11 216 3.1E-45 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS02580 2279190c1ab01b3443513e8d9c25fa0a 423 PANTHER PTHR30510 1 420 3.7E-174 T 13-09-2016 THL1_RS02580 2279190c1ab01b3443513e8d9c25fa0a 423 Pfam PF04285 Protein of unknown function (DUF444) 4 419 2.0E-182 T 13-09-2016 IPR006698 Uncharacterised protein family UPF0229 THL1_RS02580 2279190c1ab01b3443513e8d9c25fa0a 423 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 1 422 40.705 T 13-09-2016 IPR006698 Uncharacterised protein family UPF0229 THL1_RS00995 de1ab44fcf495e0928ec038a7388bba6 302 PANTHER PTHR30193:SF5 16 302 5.0E-132 T 13-09-2016 THL1_RS00995 de1ab44fcf495e0928ec038a7388bba6 302 SUPERFAMILY SSF161098 14 296 3.66E-53 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00995 de1ab44fcf495e0928ec038a7388bba6 302 Gene3D G3DSA:1.10.3720.10 14 292 2.1E-51 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00995 de1ab44fcf495e0928ec038a7388bba6 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 21 288 1.6E-10 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00995 de1ab44fcf495e0928ec038a7388bba6 302 PANTHER PTHR30193 16 302 5.0E-132 T 13-09-2016 THL1_RS10755 264a44f46463f4af991f1bd4435a8a3d 227 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS10755 264a44f46463f4af991f1bd4435a8a3d 227 PANTHER PTHR24220:SF111 8 224 1.8E-120 T 13-09-2016 THL1_RS10755 264a44f46463f4af991f1bd4435a8a3d 227 SMART SM00382 35 223 3.8E-15 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS10755 264a44f46463f4af991f1bd4435a8a3d 227 TIGRFAM TIGR02211 LolD_lipo_ex: lipoprotein releasing system, ATP-binding protein 6 225 8.8E-99 T 13-09-2016 IPR011924 Lipoprotein releasing system, ATP-binding protein GO:0005524|GO:0006810|GO:0016020 THL1_RS10755 264a44f46463f4af991f1bd4435a8a3d 227 PANTHER PTHR24220 8 224 1.8E-120 T 13-09-2016 THL1_RS10755 264a44f46463f4af991f1bd4435a8a3d 227 Gene3D G3DSA:3.40.50.300 4 226 2.1E-67 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10755 264a44f46463f4af991f1bd4435a8a3d 227 Pfam PF00005 ABC transporter 26 174 9.0E-34 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS10755 264a44f46463f4af991f1bd4435a8a3d 227 SUPERFAMILY SSF52540 6 225 2.3E-68 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03040 ce051e9fb66df4bb1b7fe53a7f1ec136 122 PANTHER PTHR30007 4 115 9.6E-30 T 13-09-2016 THL1_RS03040 ce051e9fb66df4bb1b7fe53a7f1ec136 122 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 7 78 1.7E-29 T 13-09-2016 IPR025161 Putative transposase IS4/IS5 family THL1_RS11685 0ce33faac51e5445f6a8807f18071b15 305 PIRSF PIRSF002849 1 304 2.7E-120 T 13-09-2016 IPR016366 ATPase chaperone, AAA-type, MoxR, predicted THL1_RS11685 0ce33faac51e5445f6a8807f18071b15 305 PANTHER PTHR11603 1 303 9.2E-183 T 13-09-2016 THL1_RS11685 0ce33faac51e5445f6a8807f18071b15 305 Gene3D G3DSA:1.10.8.300 196 300 9.5E-31 T 13-09-2016 THL1_RS11685 0ce33faac51e5445f6a8807f18071b15 305 Gene3D G3DSA:3.40.50.300 19 181 4.8E-40 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11685 0ce33faac51e5445f6a8807f18071b15 305 SUPERFAMILY SSF52540 14 280 1.62E-42 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11685 0ce33faac51e5445f6a8807f18071b15 305 PANTHER PTHR11603:SF155 1 303 9.2E-183 T 13-09-2016 THL1_RS11685 0ce33faac51e5445f6a8807f18071b15 305 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 35 165 5.6E-62 T 13-09-2016 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 THL1_RS16790 fd72488f9faafa7491f8703bf348b7c0 516 Gene3D G3DSA:3.40.50.300 193 367 1.4E-55 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16790 fd72488f9faafa7491f8703bf348b7c0 516 Pfam PF13185 GAF domain 23 159 1.3E-10 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS16790 fd72488f9faafa7491f8703bf348b7c0 516 SUPERFAMILY SSF46689 463 515 9.86E-7 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS16790 fd72488f9faafa7491f8703bf348b7c0 516 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 219 232 - T 13-09-2016 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THL1_RS16790 fd72488f9faafa7491f8703bf348b7c0 516 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 281 296 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS16790 fd72488f9faafa7491f8703bf348b7c0 516 Gene3D G3DSA:3.30.450.40 6 174 1.4E-18 T 13-09-2016 IPR029016 GAF domain-like THL1_RS16790 fd72488f9faafa7491f8703bf348b7c0 516 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 408 417 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS16790 fd72488f9faafa7491f8703bf348b7c0 516 SMART SM00382 215 358 1.9E-11 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS16790 fd72488f9faafa7491f8703bf348b7c0 516 PANTHER PTHR32071:SF35 164 515 1.2E-192 T 13-09-2016 THL1_RS16790 fd72488f9faafa7491f8703bf348b7c0 516 SUPERFAMILY SSF55781 5 159 3.71E-17 T 13-09-2016 IPR029016 GAF domain-like THL1_RS16790 fd72488f9faafa7491f8703bf348b7c0 516 SMART SM00065 22 170 1.3E-10 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS16790 fd72488f9faafa7491f8703bf348b7c0 516 Gene3D G3DSA:1.10.10.60 416 515 1.2E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS16790 fd72488f9faafa7491f8703bf348b7c0 516 Gene3D G3DSA:1.10.8.60 368 415 6.3E-18 T 13-09-2016 THL1_RS16790 fd72488f9faafa7491f8703bf348b7c0 516 SUPERFAMILY SSF52540 194 428 5.78E-67 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16790 fd72488f9faafa7491f8703bf348b7c0 516 PANTHER PTHR32071 164 515 1.2E-192 T 13-09-2016 THL1_RS16790 fd72488f9faafa7491f8703bf348b7c0 516 Pfam PF00158 Sigma-54 interaction domain 195 361 2.5E-67 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS26130 b23d9fc3e1bd850921267cf30f72b240 380 SUPERFAMILY SSF53756 21 370 3.77E-63 T 13-09-2016 THL1_RS26130 b23d9fc3e1bd850921267cf30f72b240 380 PANTHER PTHR12526 75 375 2.3E-42 T 13-09-2016 THL1_RS26130 b23d9fc3e1bd850921267cf30f72b240 380 Gene3D G3DSA:3.40.50.2000 163 349 4.7E-24 T 13-09-2016 THL1_RS26130 b23d9fc3e1bd850921267cf30f72b240 380 Pfam PF00534 Glycosyl transferases group 1 185 349 6.5E-26 T 13-09-2016 IPR001296 Glycosyl transferase, family 1 THL1_RS26130 b23d9fc3e1bd850921267cf30f72b240 380 Pfam PF13439 Glycosyltransferase Family 4 24 177 3.2E-12 T 13-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain THL1_RS26085 e5f26bafaa4e6b88590c9ba3f9af5798 298 Pfam PF07395 Mig-14 36 297 5.1E-118 T 13-09-2016 IPR009977 Mig-14 THL1_RS26085 e5f26bafaa4e6b88590c9ba3f9af5798 298 SUPERFAMILY SSF55729 139 294 8.48E-15 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS26085 e5f26bafaa4e6b88590c9ba3f9af5798 298 PIRSF PIRSF029703 1 298 2.8E-110 T 13-09-2016 IPR009977 Mig-14 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 7.0E-42 T 13-09-2016 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 7.0E-42 T 13-09-2016 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 251 7.0E-42 T 13-09-2016 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 7.0E-42 T 13-09-2016 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 7.0E-42 T 13-09-2016 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 Gene3D G3DSA:3.50.50.60 120 232 8.0E-35 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 300 5.7E-54 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 13-09-2016 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 Gene3D G3DSA:3.50.50.60 233 313 1.9E-10 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 312 3.9E-121 T 13-09-2016 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 PANTHER PTHR22912:SF48 1 315 2.1E-163 T 13-09-2016 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 Gene3D G3DSA:3.50.50.60 5 119 1.3E-35 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 PANTHER PTHR22912 1 315 2.1E-163 T 13-09-2016 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 SUPERFAMILY SSF51905 2 312 7.62E-57 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 1.9E-77 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 1.9E-77 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 1.9E-77 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 1.9E-77 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 237 258 1.9E-77 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 1.9E-77 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 1.9E-77 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 1.9E-77 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS23630 80731b3eb4f8754574ce99c7f2005120 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 293 1.9E-77 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS10775 b0ad85e9d9a86d4f657160ebbda0f028 211 PANTHER PTHR30625 1 195 1.3E-60 T 13-09-2016 THL1_RS10775 b0ad85e9d9a86d4f657160ebbda0f028 211 Pfam PF01618 MotA/TolQ/ExbB proton channel family 67 188 8.1E-35 T 13-09-2016 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 THL1_RS10775 b0ad85e9d9a86d4f657160ebbda0f028 211 PANTHER PTHR30625:SF0 1 195 1.3E-60 T 13-09-2016 THL1_RS09050 8f37497db8bad0100ddbdfcd987d0e11 173 Gene3D G3DSA:3.40.50.300 3 169 6.9E-62 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09050 8f37497db8bad0100ddbdfcd987d0e11 173 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 4 166 1.3E-58 T 13-09-2016 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148|UniPathway: UPA00148 THL1_RS09050 8f37497db8bad0100ddbdfcd987d0e11 173 PANTHER PTHR34848 1 171 4.0E-73 T 13-09-2016 THL1_RS09050 8f37497db8bad0100ddbdfcd987d0e11 173 SUPERFAMILY SSF52540 4 169 3.93E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09050 8f37497db8bad0100ddbdfcd987d0e11 173 PIRSF PIRSF006135 1 171 1.3E-51 T 13-09-2016 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148|UniPathway: UPA00148 THL1_RS00160 7ab31097b152cefccff25fb72427001a 122 PANTHER PTHR36423 9 120 1.1E-18 T 13-09-2016 THL1_RS00160 7ab31097b152cefccff25fb72427001a 122 Gene3D G3DSA:3.30.70.1240 2 113 3.1E-42 T 13-09-2016 IPR023389 DOPA-like domain THL1_RS00160 7ab31097b152cefccff25fb72427001a 122 SUPERFAMILY SSF143410 3 111 3.66E-44 T 13-09-2016 IPR023389 DOPA-like domain THL1_RS00160 7ab31097b152cefccff25fb72427001a 122 Pfam PF08883 Dopa 4,5-dioxygenase family 12 111 8.0E-34 T 13-09-2016 IPR014980 Dopa 4,5-dioxygenase THL1_RS00160 7ab31097b152cefccff25fb72427001a 122 PIRSF PIRSF028139 2 115 2.6E-45 T 13-09-2016 IPR014980 Dopa 4,5-dioxygenase THL1_RS06075 1cfa50b22fb5647b16b73235b6ed33ff 127 SUPERFAMILY SSF46955 48 104 7.69E-5 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS06075 1cfa50b22fb5647b16b73235b6ed33ff 127 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 46 96 1.1E-18 T 13-09-2016 IPR010260 Prophage CP4-57 regulatory protein (AlpA) THL1_RS06075 1cfa50b22fb5647b16b73235b6ed33ff 127 PANTHER PTHR36154 43 110 2.0E-12 T 13-09-2016 THL1_RS16985 7bddddfd2efb648d898fa3d897a67fc7 463 PANTHER PTHR30354 1 463 3.8E-243 T 13-09-2016 THL1_RS16985 7bddddfd2efb648d898fa3d897a67fc7 463 PANTHER PTHR30354:SF7 1 463 3.8E-243 T 13-09-2016 THL1_RS25355 f64d84cced9b5bff19565dcd864aef86 311 SMART SM00858 58 118 6.7E-8 T 13-09-2016 IPR013974 SAF domain THL1_RS25355 f64d84cced9b5bff19565dcd864aef86 311 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 12 307 3.6E-56 T 13-09-2016 IPR017592 Pilus assembly, Flp-type CpaB THL1_RS25355 f64d84cced9b5bff19565dcd864aef86 311 Pfam PF08666 SAF domain 59 115 2.1E-4 T 13-09-2016 IPR013974 SAF domain THL1_RS25355 f64d84cced9b5bff19565dcd864aef86 311 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 122 240 4.5E-28 T 13-09-2016 IPR031571 Flp pilus assembly protein RcpC/CpaB domain THL1_RS10850 0c86ba108691b50e7bfd0d9e3f49c99d 124 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 4 122 2.1E-42 T 13-09-2016 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 UniPathway: UPA00223 THL1_RS10850 0c86ba108691b50e7bfd0d9e3f49c99d 124 ProSitePatterns PS01000 Succinate dehydrogenase cytochrome b subunit signature 1. 5 29 - T 13-09-2016 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 UniPathway: UPA00223 THL1_RS10850 0c86ba108691b50e7bfd0d9e3f49c99d 124 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2 118 2.0E-31 T 13-09-2016 IPR000701 Succinate dehydrogenase/Fumarate reductase, transmembrane subunit GO:0016627 UniPathway: UPA00223 THL1_RS10850 0c86ba108691b50e7bfd0d9e3f49c99d 124 PANTHER PTHR10978:SF4 1 124 6.8E-66 T 13-09-2016 THL1_RS10850 0c86ba108691b50e7bfd0d9e3f49c99d 124 SUPERFAMILY SSF81343 2 124 7.03E-35 T 13-09-2016 THL1_RS10850 0c86ba108691b50e7bfd0d9e3f49c99d 124 ProSitePatterns PS01001 Succinate dehydrogenase cytochrome b subunit signature 2. 80 93 - T 13-09-2016 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 UniPathway: UPA00223 THL1_RS10850 0c86ba108691b50e7bfd0d9e3f49c99d 124 PIRSF PIRSF000178 1 124 1.6E-31 T 13-09-2016 THL1_RS10850 0c86ba108691b50e7bfd0d9e3f49c99d 124 PANTHER PTHR10978 1 124 6.8E-66 T 13-09-2016 THL1_RS10850 0c86ba108691b50e7bfd0d9e3f49c99d 124 Gene3D G3DSA:1.20.1300.10 2 124 2.3E-41 T 13-09-2016 THL1_RS18965 5b3d71f4cfdc1c52954ab53c97f67dc5 221 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 114 3.6E-24 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS18965 5b3d71f4cfdc1c52954ab53c97f67dc5 221 PANTHER PTHR30614 1 221 6.9E-125 T 13-09-2016 THL1_RS18965 5b3d71f4cfdc1c52954ab53c97f67dc5 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 219 7.0E-18 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS18965 5b3d71f4cfdc1c52954ab53c97f67dc5 221 Gene3D G3DSA:1.10.3720.10 11 219 1.6E-40 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS18965 5b3d71f4cfdc1c52954ab53c97f67dc5 221 PANTHER PTHR30614:SF1 1 221 6.9E-125 T 13-09-2016 IPR030205 Glutamate/aspartate transport system permease protein GltK/AatM GO:0006865|GO:0016021|GO:0043190 THL1_RS18965 5b3d71f4cfdc1c52954ab53c97f67dc5 221 SUPERFAMILY SSF161098 11 205 1.05E-37 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS24715 5ddb27fb5c0d31054268ce93161a8948 453 PANTHER PTHR15498:SF49 43 286 8.7E-37 T 13-09-2016 THL1_RS24715 5ddb27fb5c0d31054268ce93161a8948 453 PANTHER PTHR15498 43 286 8.7E-37 T 13-09-2016 THL1_RS17245 125014a628d5e8a60bf2bc2a33dbc4e9 474 Pfam PF07044 Protein of unknown function (DUF1329) 96 469 1.6E-116 T 13-09-2016 IPR010752 Protein of unknown function DUF1329 THL1_RS17245 125014a628d5e8a60bf2bc2a33dbc4e9 474 Gene3D G3DSA:2.50.20.10 354 469 1.6E-34 T 13-09-2016 THL1_RS17245 125014a628d5e8a60bf2bc2a33dbc4e9 474 Gene3D G3DSA:2.50.20.10 171 321 1.6E-34 T 13-09-2016 THL1_RS26750 7127ee29b2ff4ac031952241c3fe7db4 85 Pfam PF09932 Uncharacterized conserved protein (DUF2164) 11 83 1.6E-27 T 13-09-2016 IPR018680 Protein of unknown function DUF2164 THL1_RS02170 0fe8d6c0c66cdebe0048dad46f54c42b 393 PANTHER PTHR13693:SF53 5 385 2.9E-178 T 13-09-2016 THL1_RS02170 0fe8d6c0c66cdebe0048dad46f54c42b 393 Gene3D G3DSA:3.40.640.10 56 269 7.3E-82 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS02170 0fe8d6c0c66cdebe0048dad46f54c42b 393 SUPERFAMILY SSF53383 6 383 1.3E-112 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS02170 0fe8d6c0c66cdebe0048dad46f54c42b 393 Hamap MF_01693 8-amino-7-oxononanoate synthase [bioF]. 1 382 51.606 T 13-09-2016 IPR022834 8-amino-7-oxononanoate synthase, Proteobacteria GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147|UniPathway: UPA00078 THL1_RS02170 0fe8d6c0c66cdebe0048dad46f54c42b 393 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 17 378 2.6E-149 T 13-09-2016 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147|UniPathway: UPA00078 THL1_RS02170 0fe8d6c0c66cdebe0048dad46f54c42b 393 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 233 242 - T 13-09-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 THL1_RS02170 0fe8d6c0c66cdebe0048dad46f54c42b 393 PANTHER PTHR13693 5 385 2.9E-178 T 13-09-2016 THL1_RS02170 0fe8d6c0c66cdebe0048dad46f54c42b 393 Pfam PF00155 Aminotransferase class I and II 39 378 5.1E-59 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS02170 0fe8d6c0c66cdebe0048dad46f54c42b 393 Gene3D G3DSA:3.90.1150.10 270 381 2.1E-34 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS09760 4e7dcae2fcabaeead8fff88339032a6f 749 PANTHER PTHR11472 178 744 1.2E-79 T 13-09-2016 THL1_RS09760 4e7dcae2fcabaeead8fff88339032a6f 749 Pfam PF06777 Helical and beta-bridge domain 512 567 2.4E-7 T 13-09-2016 IPR010643 Helical and beta-bridge domain THL1_RS09760 4e7dcae2fcabaeead8fff88339032a6f 749 SMART SM00491 598 733 8.4E-12 T 13-09-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 THL1_RS09760 4e7dcae2fcabaeead8fff88339032a6f 749 SMART SM00488 174 417 0.0012 T 13-09-2016 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 THL1_RS09760 4e7dcae2fcabaeead8fff88339032a6f 749 Pfam PF06733 DEAD_2 267 386 2.2E-14 T 13-09-2016 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 THL1_RS09760 4e7dcae2fcabaeead8fff88339032a6f 749 Gene3D G3DSA:3.40.50.300 577 671 7.3E-6 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09760 4e7dcae2fcabaeead8fff88339032a6f 749 Gene3D G3DSA:3.40.50.300 703 729 7.3E-6 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09760 4e7dcae2fcabaeead8fff88339032a6f 749 Pfam PF13307 Helicase C-terminal domain 586 744 8.3E-34 T 13-09-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 THL1_RS09760 4e7dcae2fcabaeead8fff88339032a6f 749 SUPERFAMILY SSF52540 201 255 1.06E-15 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09760 4e7dcae2fcabaeead8fff88339032a6f 749 SUPERFAMILY SSF52540 315 388 1.06E-15 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09760 4e7dcae2fcabaeead8fff88339032a6f 749 SUPERFAMILY SSF52540 557 727 1.06E-15 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09760 4e7dcae2fcabaeead8fff88339032a6f 749 SUPERFAMILY SSF52540 513 527 1.06E-15 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09760 4e7dcae2fcabaeead8fff88339032a6f 749 Gene3D G3DSA:3.40.50.300 178 281 2.9E-13 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09760 4e7dcae2fcabaeead8fff88339032a6f 749 Gene3D G3DSA:3.40.50.300 330 397 2.9E-13 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09760 4e7dcae2fcabaeead8fff88339032a6f 749 Gene3D G3DSA:3.40.50.300 515 527 2.9E-13 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17585 3e83a8426a139450d95fd859eb652f7c 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 63 17.074 T 13-09-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THL1_RS17585 3e83a8426a139450d95fd859eb652f7c 64 Pfam PF01632 Ribosomal protein L35 2 61 1.8E-24 T 13-09-2016 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS17585 3e83a8426a139450d95fd859eb652f7c 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 8.7E-20 T 13-09-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THL1_RS17585 3e83a8426a139450d95fd859eb652f7c 64 PRINTS PR00064 Ribosomal protein L35 signature 20 34 8.7E-20 T 13-09-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THL1_RS17585 3e83a8426a139450d95fd859eb652f7c 64 PRINTS PR00064 Ribosomal protein L35 signature 35 53 8.7E-20 T 13-09-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THL1_RS17585 3e83a8426a139450d95fd859eb652f7c 64 PANTHER PTHR33343 1 61 5.2E-25 T 13-09-2016 THL1_RS17585 3e83a8426a139450d95fd859eb652f7c 64 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 30 - T 13-09-2016 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS17585 3e83a8426a139450d95fd859eb652f7c 64 SUPERFAMILY SSF143034 2 61 2.49E-21 T 13-09-2016 THL1_RS17585 3e83a8426a139450d95fd859eb652f7c 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 1.0E-25 T 13-09-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THL1_RS00835 3e23b3ca867b069a376ac871a56d0458 333 PANTHER PTHR10314 1 320 2.2E-112 T 13-09-2016 THL1_RS00835 3e23b3ca867b069a376ac871a56d0458 333 PANTHER PTHR10314:SF105 1 320 2.2E-112 T 13-09-2016 THL1_RS00835 3e23b3ca867b069a376ac871a56d0458 333 PIRSF PIRSF006278 1 332 1.1E-95 T 13-09-2016 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase THL1_RS00835 3e23b3ca867b069a376ac871a56d0458 333 Gene3D G3DSA:3.40.50.1100 113 328 1.2E-65 T 13-09-2016 THL1_RS00835 3e23b3ca867b069a376ac871a56d0458 333 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 15 319 5.7E-52 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS00835 3e23b3ca867b069a376ac871a56d0458 333 SUPERFAMILY SSF53686 8 328 9.69E-82 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS00835 3e23b3ca867b069a376ac871a56d0458 333 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 12 329 1.8E-109 T 13-09-2016 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 THL1_RS24795 65f521933bde24f96298b3eb9553ea20 563 PANTHER PTHR30258 132 560 4.6E-158 T 13-09-2016 THL1_RS24795 65f521933bde24f96298b3eb9553ea20 563 Pfam PF00437 Type II/IV secretion system protein 184 451 1.6E-68 T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS24795 65f521933bde24f96298b3eb9553ea20 563 SUPERFAMILY SSF160246 18 136 3.14E-9 T 13-09-2016 THL1_RS24795 65f521933bde24f96298b3eb9553ea20 563 Gene3D G3DSA:3.40.50.300 292 560 1.5E-94 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24795 65f521933bde24f96298b3eb9553ea20 563 Gene3D G3DSA:3.30.450.90 153 280 2.5E-40 T 13-09-2016 THL1_RS24795 65f521933bde24f96298b3eb9553ea20 563 SUPERFAMILY SSF52540 169 560 8.65E-93 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24795 65f521933bde24f96298b3eb9553ea20 563 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 380 394 - T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS24795 65f521933bde24f96298b3eb9553ea20 563 PANTHER PTHR30258:SF2 132 560 4.6E-158 T 13-09-2016 THL1_RS24795 65f521933bde24f96298b3eb9553ea20 563 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 46 139 2.1E-9 T 13-09-2016 IPR007831 General secretory system II, protein E, N-terminal GO:0005524|GO:0006810 THL1_RS07910 1ecfaf19e9de8215636483a2538189fb 187 SUPERFAMILY SSF69118 5 176 1.31E-28 T 13-09-2016 IPR029032 AhpD-like THL1_RS07910 1ecfaf19e9de8215636483a2538189fb 187 PANTHER PTHR34846:SF1 1 174 3.8E-44 T 13-09-2016 THL1_RS07910 1ecfaf19e9de8215636483a2538189fb 187 PANTHER PTHR34846 1 174 3.8E-44 T 13-09-2016 THL1_RS07910 1ecfaf19e9de8215636483a2538189fb 187 Gene3D G3DSA:1.20.1290.10 37 177 3.6E-24 T 13-09-2016 IPR029032 AhpD-like THL1_RS11540 4e2360363a830b7382a967c8a68bf9d3 449 SUPERFAMILY SSF51569 3 445 1.76E-204 T 13-09-2016 THL1_RS11540 4e2360363a830b7382a967c8a68bf9d3 449 PANTHER PTHR21337 4 449 1.8E-304 T 13-09-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 THL1_RS11540 4e2360363a830b7382a967c8a68bf9d3 449 Pfam PF01474 Class-II DAHP synthetase family 6 441 5.7E-206 T 13-09-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 THL1_RS11540 4e2360363a830b7382a967c8a68bf9d3 449 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 6 447 5.8E-222 T 13-09-2016 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 THL1_RS17805 ebfc5d3613085a96f3b3761621b6e21a 104 SUPERFAMILY SSF55718 4 102 1.85E-28 T 13-09-2016 IPR003033 SCP2 sterol-binding domain THL1_RS17805 ebfc5d3613085a96f3b3761621b6e21a 104 Gene3D G3DSA:3.30.1050.10 3 102 1.4E-28 T 13-09-2016 IPR003033 SCP2 sterol-binding domain THL1_RS17805 ebfc5d3613085a96f3b3761621b6e21a 104 PANTHER PTHR10094 23 102 3.8E-31 T 13-09-2016 THL1_RS17805 ebfc5d3613085a96f3b3761621b6e21a 104 Pfam PF02036 SCP-2 sterol transfer family 15 102 2.7E-21 T 13-09-2016 IPR003033 SCP2 sterol-binding domain THL1_RS17805 ebfc5d3613085a96f3b3761621b6e21a 104 PANTHER PTHR10094:SF13 23 102 3.8E-31 T 13-09-2016 THL1_RS03010 a0a62f5b977dd752d3bec08fdd07ce71 167 PANTHER PTHR33619 1 160 6.8E-34 T 13-09-2016 THL1_RS03010 a0a62f5b977dd752d3bec08fdd07ce71 167 Gene3D G3DSA:3.10.560.10 85 153 7.5E-14 T 13-09-2016 THL1_RS03010 a0a62f5b977dd752d3bec08fdd07ce71 167 Pfam PF02563 Polysaccharide biosynthesis/export protein 14 88 6.6E-19 T 13-09-2016 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 THL1_RS03010 a0a62f5b977dd752d3bec08fdd07ce71 167 Gene3D G3DSA:3.30.1950.10 22 84 5.9E-18 T 13-09-2016 THL1_RS03010 a0a62f5b977dd752d3bec08fdd07ce71 167 Pfam PF10531 SLBB domain 95 138 2.1E-12 T 13-09-2016 IPR019554 Soluble ligand binding domain THL1_RS08585 b794533ffc3799136a43639fdc077c53 344 SUPERFAMILY SSF55326 6 160 6.15E-40 T 13-09-2016 THL1_RS08585 b794533ffc3799136a43639fdc077c53 344 PANTHER PTHR10256 1 333 2.0E-152 T 13-09-2016 THL1_RS08585 b794533ffc3799136a43639fdc077c53 344 Pfam PF02769 AIR synthase related protein, C-terminal domain 169 343 5.7E-31 T 13-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain THL1_RS08585 b794533ffc3799136a43639fdc077c53 344 Pfam PF00586 AIR synthase related protein, N-terminal domain 49 156 2.6E-20 T 13-09-2016 IPR016188 PurM-like, N-terminal domain THL1_RS08585 b794533ffc3799136a43639fdc077c53 344 Gene3D G3DSA:3.90.650.10 175 340 1.3E-18 T 13-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain THL1_RS08585 b794533ffc3799136a43639fdc077c53 344 SUPERFAMILY SSF56042 163 339 7.92E-52 T 13-09-2016 IPR010918 AIR synthase-related protein, C-terminal domain THL1_RS08585 b794533ffc3799136a43639fdc077c53 344 Gene3D G3DSA:3.30.1330.10 39 161 8.4E-32 T 13-09-2016 IPR016188 PurM-like, N-terminal domain THL1_RS08585 b794533ffc3799136a43639fdc077c53 344 Hamap MF_00625 Selenide, water dikinase [selD]. 4 344 45.684 T 13-09-2016 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 THL1_RS08585 b794533ffc3799136a43639fdc077c53 344 PIRSF PIRSF036407 1 344 5.7E-115 T 13-09-2016 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 THL1_RS08585 b794533ffc3799136a43639fdc077c53 344 TIGRFAM TIGR00476 selD: selenide, water dikinase 6 311 4.4E-136 T 13-09-2016 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 THL1_RS00110 b019e3bd8b55d187bf918524bc170180 341 PANTHER PTHR34700:SF2 11 340 2.1E-95 T 13-09-2016 THL1_RS00110 b019e3bd8b55d187bf918524bc170180 341 SUPERFAMILY SSF54106 29 77 4.05E-7 T 13-09-2016 IPR018392 LysM domain THL1_RS00110 b019e3bd8b55d187bf918524bc170180 341 PANTHER PTHR34700 11 340 2.1E-95 T 13-09-2016 THL1_RS00110 b019e3bd8b55d187bf918524bc170180 341 Gene3D G3DSA:3.10.350.10 29 77 1.0E-6 T 13-09-2016 IPR018392 LysM domain THL1_RS00110 b019e3bd8b55d187bf918524bc170180 341 Pfam PF01476 LysM domain 31 75 1.2E-11 T 13-09-2016 IPR018392 LysM domain THL1_RS22410 dfd1283ed1d2b4aeef23d0ac3f0b3946 137 PANTHER PTHR21366:SF0 4 132 3.0E-20 T 13-09-2016 THL1_RS22410 dfd1283ed1d2b4aeef23d0ac3f0b3946 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 121 1.8E-18 T 13-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain THL1_RS22410 dfd1283ed1d2b4aeef23d0ac3f0b3946 137 Gene3D G3DSA:3.10.180.10 3 124 1.3E-26 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS22410 dfd1283ed1d2b4aeef23d0ac3f0b3946 137 SUPERFAMILY SSF54593 4 126 8.46E-30 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS22410 dfd1283ed1d2b4aeef23d0ac3f0b3946 137 PANTHER PTHR21366 4 132 3.0E-20 T 13-09-2016 THL1_RS16775 92eab46dee766ffec455604676f928f4 396 Pfam PF05940 NnrS protein 14 390 8.5E-105 T 13-09-2016 IPR010266 NnrS THL1_RS16355 c84a1ab63e4c0fff2482bc7e66fbfa4a 160 Pfam PF01740 STAS domain 6 103 5.0E-5 T 13-09-2016 IPR002645 STAS domain THL1_RS16355 c84a1ab63e4c0fff2482bc7e66fbfa4a 160 Gene3D G3DSA:3.30.750.24 5 106 6.3E-15 T 13-09-2016 IPR002645 STAS domain THL1_RS16355 c84a1ab63e4c0fff2482bc7e66fbfa4a 160 SUPERFAMILY SSF52091 6 106 2.75E-14 T 13-09-2016 IPR002645 STAS domain THL1_RS16355 c84a1ab63e4c0fff2482bc7e66fbfa4a 160 PIRSF PIRSF029548 1 160 5.1E-103 T 13-09-2016 IPR014557 Uncharacterised conserved protein UCP029548, STAS-type THL1_RS06435 171dd1d2703d2c0f228f31e6ce92d2f6 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 6 32 7.0E-63 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS06435 171dd1d2703d2c0f228f31e6ce92d2f6 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 38 50 7.0E-63 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS06435 171dd1d2703d2c0f228f31e6ce92d2f6 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 88 110 7.0E-63 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS06435 171dd1d2703d2c0f228f31e6ce92d2f6 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 110 137 7.0E-63 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS06435 171dd1d2703d2c0f228f31e6ce92d2f6 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 234 256 7.0E-63 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS06435 171dd1d2703d2c0f228f31e6ce92d2f6 283 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 256 281 7.0E-63 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS06435 171dd1d2703d2c0f228f31e6ce92d2f6 283 PANTHER PTHR10520 1 276 1.1E-144 T 13-09-2016 THL1_RS06435 171dd1d2703d2c0f228f31e6ce92d2f6 283 Pfam PF00551 Formyl transferase 87 262 8.7E-40 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS06435 171dd1d2703d2c0f228f31e6ce92d2f6 283 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 1 282 48.535 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS06435 171dd1d2703d2c0f228f31e6ce92d2f6 283 Gene3D G3DSA:3.40.50.170 87 282 1.5E-57 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS06435 171dd1d2703d2c0f228f31e6ce92d2f6 283 Gene3D G3DSA:3.30.70.260 1 82 7.0E-20 T 13-09-2016 THL1_RS06435 171dd1d2703d2c0f228f31e6ce92d2f6 283 PIRSF PIRSF036480 1 283 1.7E-118 T 13-09-2016 THL1_RS06435 171dd1d2703d2c0f228f31e6ce92d2f6 283 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 5 282 7.3E-109 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS06435 171dd1d2703d2c0f228f31e6ce92d2f6 283 SUPERFAMILY SSF55021 3 84 2.42E-14 T 13-09-2016 THL1_RS06435 171dd1d2703d2c0f228f31e6ce92d2f6 283 SUPERFAMILY SSF53328 87 283 2.62E-62 T 13-09-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THL1_RS06435 171dd1d2703d2c0f228f31e6ce92d2f6 283 PANTHER PTHR10520:SF7 1 276 1.1E-144 T 13-09-2016 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|UniPathway: UPA00074 THL1_RS10635 d006ebf7ddedcafb17de790c958dc626 157 Gene3D G3DSA:3.40.50.300 41 153 1.3E-27 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10635 d006ebf7ddedcafb17de790c958dc626 157 PANTHER PTHR35369 1 154 1.6E-16 T 13-09-2016 THL1_RS10635 d006ebf7ddedcafb17de790c958dc626 157 Pfam PF03846 Cell division inhibitor SulA 40 130 1.6E-7 T 13-09-2016 IPR004596 Cell division suppressor protein, SulA GO:0009276|GO:0009432|GO:0051782 THL1_RS10635 d006ebf7ddedcafb17de790c958dc626 157 SUPERFAMILY SSF52540 41 153 5.1E-23 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11270 3e406c72e0abe8bae678725cfb4128e4 313 Gene3D G3DSA:3.40.50.1820 69 308 3.3E-74 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS11270 3e406c72e0abe8bae678725cfb4128e4 313 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 84 100 - T 13-09-2016 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 THL1_RS11270 3e406c72e0abe8bae678725cfb4128e4 313 PANTHER PTHR23024 83 304 2.8E-68 T 13-09-2016 THL1_RS11270 3e406c72e0abe8bae678725cfb4128e4 313 SUPERFAMILY SSF53474 70 307 2.77E-64 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS11270 3e406c72e0abe8bae678725cfb4128e4 313 Pfam PF07859 alpha/beta hydrolase fold 84 284 5.1E-63 T 13-09-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 THL1_RS20580 540646af16e8fa4660141a6f01367923 175 SUPERFAMILY SSF54427 1 167 8.38E-35 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS20580 540646af16e8fa4660141a6f01367923 175 Gene3D G3DSA:3.10.450.50 8 136 2.9E-29 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS20580 540646af16e8fa4660141a6f01367923 175 Pfam PF13577 SnoaL-like domain 6 129 9.6E-25 T 13-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain THL1_RS24365 41b6b70df3682fb2e2c9d5c85e8e3c1c 119 SMART SM00749 55 118 2.1E-7 T 13-09-2016 IPR014004 Transport-associated and nodulation domain, bacteria THL1_RS24365 41b6b70df3682fb2e2c9d5c85e8e3c1c 119 PANTHER PTHR34606 43 116 3.6E-26 T 13-09-2016 THL1_RS24365 41b6b70df3682fb2e2c9d5c85e8e3c1c 119 Pfam PF04972 BON domain 50 112 5.5E-18 T 13-09-2016 IPR007055 BON domain THL1_RS11325 08cde1100e92beae56e0a3521effffe0 316 PANTHER PTHR34595 1 315 9.6E-120 T 13-09-2016 THL1_RS11325 08cde1100e92beae56e0a3521effffe0 316 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 313 2.0E-94 T 13-09-2016 IPR007296 Domain of unknown function DUF403 THL1_RS01295 007bfe277b6b58bfe4408aa745baaee1 197 PANTHER PTHR33219:SF5 9 196 2.5E-73 T 13-09-2016 THL1_RS01295 007bfe277b6b58bfe4408aa745baaee1 197 PANTHER PTHR33219 9 196 2.5E-73 T 13-09-2016 THL1_RS01295 007bfe277b6b58bfe4408aa745baaee1 197 Pfam PF02325 YGGT family 110 179 2.5E-20 T 13-09-2016 IPR003425 CCB3/YggT GO:0016020 THL1_RS01295 007bfe277b6b58bfe4408aa745baaee1 197 Pfam PF02325 YGGT family 14 82 9.6E-19 T 13-09-2016 IPR003425 CCB3/YggT GO:0016020 THL1_RS13790 ff8a63513021381f1a67c234cb2249c5 218 Gene3D G3DSA:1.10.10.10 147 215 8.5E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13790 ff8a63513021381f1a67c234cb2249c5 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 214 1.8E-13 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS13790 ff8a63513021381f1a67c234cb2249c5 218 SUPERFAMILY SSF46894 143 215 1.02E-18 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS13790 ff8a63513021381f1a67c234cb2249c5 218 SMART SM00421 159 216 3.2E-18 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS13790 ff8a63513021381f1a67c234cb2249c5 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 9.7E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS13790 ff8a63513021381f1a67c234cb2249c5 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 9.7E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS13790 ff8a63513021381f1a67c234cb2249c5 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 9.7E-10 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS26225 4b42ee1c470b2ac8f1f75c74f55b6c1b 580 Gene3D G3DSA:3.30.465.10 497 568 9.7E-10 T 13-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THL1_RS26225 4b42ee1c470b2ac8f1f75c74f55b6c1b 580 Pfam PF03471 Transporter associated domain 496 569 9.6E-11 T 13-09-2016 IPR005170 Transporter-associated domain THL1_RS26225 4b42ee1c470b2ac8f1f75c74f55b6c1b 580 PANTHER PTHR32507 1 576 1.0E-284 T 13-09-2016 THL1_RS26225 4b42ee1c470b2ac8f1f75c74f55b6c1b 580 Pfam PF00999 Sodium/hydrogen exchanger family 15 387 1.7E-55 T 13-09-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 THL1_RS26225 4b42ee1c470b2ac8f1f75c74f55b6c1b 580 Gene3D G3DSA:3.30.70.1450 416 483 1.2E-8 T 13-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THL1_RS26225 4b42ee1c470b2ac8f1f75c74f55b6c1b 580 SUPERFAMILY SSF116726 412 483 1.24E-11 T 13-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THL1_RS26225 4b42ee1c470b2ac8f1f75c74f55b6c1b 580 Hamap MF_01075 K(+)/H(+) antiporter NhaP2 [nhaP2]. 1 574 51.622 T 13-09-2016 IPR023729 K(+)/H(+) antiporter NhaP2 GO:0005451|GO:0006812|GO:0006813|GO:0006884|GO:0016021 THL1_RS26225 4b42ee1c470b2ac8f1f75c74f55b6c1b 580 Pfam PF02080 TrkA-C domain 417 483 3.5E-13 T 13-09-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THL1_RS26225 4b42ee1c470b2ac8f1f75c74f55b6c1b 580 PANTHER PTHR32507:SF7 1 576 1.0E-284 T 13-09-2016 IPR030151 K(+)/H(+) antiporter NhaP GO:0005451|GO:0006813|GO:0016021 THL1_RS26225 4b42ee1c470b2ac8f1f75c74f55b6c1b 580 SUPERFAMILY SSF56176 497 569 3.27E-9 T 13-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THL1_RS26225 4b42ee1c470b2ac8f1f75c74f55b6c1b 580 SMART SM01091 492 571 9.5E-13 T 13-09-2016 IPR005170 Transporter-associated domain THL1_RS16585 8ca4220377d3f6596b29067edc241ca5 768 Gene3D G3DSA:3.10.450.50 700 768 1.8E-10 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS16585 8ca4220377d3f6596b29067edc241ca5 768 SUPERFAMILY SSF103642 748 767 3.6E-7 T 13-09-2016 THL1_RS16585 8ca4220377d3f6596b29067edc241ca5 768 Pfam PF02810 SEC-C motif 750 768 8.9E-10 T 13-09-2016 IPR004027 SEC-C motif THL1_RS13850 371178136d48a2f641aca4c2aaf8e8ec 163 Pfam PF08281 Sigma-70, region 4 103 154 7.3E-15 T 13-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS13850 371178136d48a2f641aca4c2aaf8e8ec 163 Gene3D G3DSA:1.10.10.10 100 160 6.7E-16 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13850 371178136d48a2f641aca4c2aaf8e8ec 163 Gene3D G3DSA:1.10.1740.10 10 73 5.4E-10 T 13-09-2016 THL1_RS13850 371178136d48a2f641aca4c2aaf8e8ec 163 PANTHER PTHR30173 8 161 1.6E-39 T 13-09-2016 THL1_RS13850 371178136d48a2f641aca4c2aaf8e8ec 163 SUPERFAMILY SSF88659 86 159 1.78E-15 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS13850 371178136d48a2f641aca4c2aaf8e8ec 163 Pfam PF04542 Sigma-70 region 2 11 72 3.4E-10 T 13-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS13850 371178136d48a2f641aca4c2aaf8e8ec 163 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 158 3.6E-27 T 13-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS13850 371178136d48a2f641aca4c2aaf8e8ec 163 PANTHER PTHR30173:SF30 8 161 1.6E-39 T 13-09-2016 THL1_RS13850 371178136d48a2f641aca4c2aaf8e8ec 163 SUPERFAMILY SSF88946 8 90 5.49E-11 T 13-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS12045 ff17a30438b68184ec00a6283b8df0b9 288 SUPERFAMILY SSF46689 234 280 9.86E-6 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS12045 ff17a30438b68184ec00a6283b8df0b9 288 SMART SM00342 198 281 2.3E-16 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS12045 ff17a30438b68184ec00a6283b8df0b9 288 Pfam PF12833 Helix-turn-helix domain 204 277 4.1E-17 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS12045 ff17a30438b68184ec00a6283b8df0b9 288 Pfam PF06719 AraC-type transcriptional regulator N-terminus 18 169 3.3E-53 T 13-09-2016 IPR009594 Transcription regulator HTH, AraC, N-terminal THL1_RS12045 ff17a30438b68184ec00a6283b8df0b9 288 SUPERFAMILY SSF46689 182 231 4.66E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS12045 ff17a30438b68184ec00a6283b8df0b9 288 Gene3D G3DSA:1.10.10.60 179 235 2.4E-17 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS12045 ff17a30438b68184ec00a6283b8df0b9 288 PANTHER PTHR11019 19 288 1.5E-93 T 13-09-2016 THL1_RS12045 ff17a30438b68184ec00a6283b8df0b9 288 PANTHER PTHR11019:SF81 19 288 1.5E-93 T 13-09-2016 THL1_RS12045 ff17a30438b68184ec00a6283b8df0b9 288 Gene3D G3DSA:1.10.10.60 236 277 9.9E-6 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS16005 c102f8e8847e38a7d49b7a7d46510263 338 Gene3D G3DSA:1.20.1600.10 88 146 7.0E-4 T 13-09-2016 THL1_RS16005 c102f8e8847e38a7d49b7a7d46510263 338 PANTHER PTHR30469:SF11 27 335 1.2E-86 T 13-09-2016 THL1_RS16005 c102f8e8847e38a7d49b7a7d46510263 338 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 39 252 1.0E-30 T 13-09-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THL1_RS16005 c102f8e8847e38a7d49b7a7d46510263 338 Gene3D G3DSA:2.40.50.100 52 85 2.0E-18 T 13-09-2016 THL1_RS16005 c102f8e8847e38a7d49b7a7d46510263 338 Gene3D G3DSA:2.40.50.100 147 177 2.0E-18 T 13-09-2016 THL1_RS16005 c102f8e8847e38a7d49b7a7d46510263 338 PANTHER PTHR30469 27 335 1.2E-86 T 13-09-2016 THL1_RS16005 c102f8e8847e38a7d49b7a7d46510263 338 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 27 332 1.6E-80 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS16005 c102f8e8847e38a7d49b7a7d46510263 338 SUPERFAMILY SSF111369 44 256 1.44E-44 T 13-09-2016 THL1_RS02390 77230801a5e0a82397e908d78bfe1c89 142 Pfam PF07681 DoxX 17 93 2.7E-10 T 13-09-2016 IPR032808 DoxX family THL1_RS02390 77230801a5e0a82397e908d78bfe1c89 142 PANTHER PTHR33452 1 134 4.7E-44 T 13-09-2016 THL1_RS02390 77230801a5e0a82397e908d78bfe1c89 142 PANTHER PTHR33452:SF4 1 134 4.7E-44 T 13-09-2016 THL1_RS16850 c35732c3ddd5acd70b3224551d54eb28 74 Gene3D G3DSA:1.10.260.40 5 69 5.2E-24 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS16850 c35732c3ddd5acd70b3224551d54eb28 74 SUPERFAMILY SSF47413 7 65 7.64E-12 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS16850 c35732c3ddd5acd70b3224551d54eb28 74 Pfam PF15943 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 7 67 4.6E-22 T 13-09-2016 IPR031856 Putative bacterial antitoxin YdaS THL1_RS05070 3b531a724f4a04a7b9891e5a15fa074b 290 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 225 240 4.0E-26 T 13-09-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- THL1_RS05070 3b531a724f4a04a7b9891e5a15fa074b 290 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 213 224 4.0E-26 T 13-09-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- THL1_RS05070 3b531a724f4a04a7b9891e5a15fa074b 290 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 145 162 4.0E-26 T 13-09-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- THL1_RS05070 3b531a724f4a04a7b9891e5a15fa074b 290 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 202 212 4.0E-26 T 13-09-2016 IPR014032 Peptidase A24A, prepilin type IV, bacterial KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- THL1_RS05070 3b531a724f4a04a7b9891e5a15fa074b 290 Pfam PF01478 Type IV leader peptidase family 136 245 4.6E-25 T 13-09-2016 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 THL1_RS05070 3b531a724f4a04a7b9891e5a15fa074b 290 PANTHER PTHR30487 57 288 9.7E-118 T 13-09-2016 THL1_RS05070 3b531a724f4a04a7b9891e5a15fa074b 290 PANTHER PTHR30487 2 38 9.7E-118 T 13-09-2016 THL1_RS05070 3b531a724f4a04a7b9891e5a15fa074b 290 PANTHER PTHR30487:SF0 57 288 9.7E-118 T 13-09-2016 THL1_RS05070 3b531a724f4a04a7b9891e5a15fa074b 290 PANTHER PTHR30487:SF0 2 38 9.7E-118 T 13-09-2016 THL1_RS05070 3b531a724f4a04a7b9891e5a15fa074b 290 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 20 126 1.7E-34 T 13-09-2016 IPR010627 Peptidase A24A, N-terminal KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- THL1_RS16450 314b873a93e0ec170b4b12691ca42303 332 Pfam PF11740 Plasmid replication region DNA-binding N-term 8 116 4.5E-24 T 13-09-2016 IPR021104 KfrA, N-terminal DNA-binding domain THL1_RS12660 6290f9e4187f672934735d0c0fdc5b53 458 Gene3D G3DSA:1.20.1250.20 239 425 6.2E-16 T 13-09-2016 THL1_RS12660 6290f9e4187f672934735d0c0fdc5b53 458 Gene3D G3DSA:1.20.1250.20 16 218 2.6E-20 T 13-09-2016 THL1_RS12660 6290f9e4187f672934735d0c0fdc5b53 458 ProSitePatterns PS00216 Sugar transport proteins signature 1. 295 311 - T 13-09-2016 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 THL1_RS12660 6290f9e4187f672934735d0c0fdc5b53 458 PANTHER PTHR23508 7 446 6.1E-248 T 13-09-2016 THL1_RS12660 6290f9e4187f672934735d0c0fdc5b53 458 SUPERFAMILY SSF103473 10 431 3.4E-58 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS12660 6290f9e4187f672934735d0c0fdc5b53 458 PANTHER PTHR23508:SF19 7 446 6.1E-248 T 13-09-2016 THL1_RS12660 6290f9e4187f672934735d0c0fdc5b53 458 Pfam PF07690 Major Facilitator Superfamily 48 379 2.0E-25 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS23230 401a41f804f8a19719001939195c613f 102 SUPERFAMILY SSF46785 4 100 1.3E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS23230 401a41f804f8a19719001939195c613f 102 PANTHER PTHR33154:SF6 4 100 1.1E-22 T 13-09-2016 THL1_RS23230 401a41f804f8a19719001939195c613f 102 SMART SM00418 9 100 1.9E-12 T 13-09-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THL1_RS23230 401a41f804f8a19719001939195c613f 102 Pfam PF12840 Helix-turn-helix domain 8 80 9.9E-18 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS23230 401a41f804f8a19719001939195c613f 102 Gene3D G3DSA:1.10.10.10 3 100 7.4E-31 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS23230 401a41f804f8a19719001939195c613f 102 PANTHER PTHR33154 4 100 1.1E-22 T 13-09-2016 THL1_RS23300 7caa1aa08aa4a668355b09748e4ea926 435 Pfam PF03573 outer membrane porin, OprD family 24 400 2.1E-16 T 13-09-2016 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 THL1_RS23300 7caa1aa08aa4a668355b09748e4ea926 435 Gene3D G3DSA:2.40.160.10 34 418 2.6E-28 T 13-09-2016 IPR023614 Porin domain THL1_RS23845 1142c6a007eea416b75f3592463422dc 505 Gene3D G3DSA:3.50.50.60 150 332 8.1E-20 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23845 1142c6a007eea416b75f3592463422dc 505 Gene3D G3DSA:3.50.50.60 7 75 8.1E-20 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23845 1142c6a007eea416b75f3592463422dc 505 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 9 491 1.4E-240 T 13-09-2016 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254|UniPathway: UPA00223 THL1_RS23845 1142c6a007eea416b75f3592463422dc 505 SUPERFAMILY SSF51905 9 280 2.85E-19 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS23845 1142c6a007eea416b75f3592463422dc 505 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 8 494 2.8E-228 T 13-09-2016 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254|UniPathway: UPA00223 THL1_RS23845 1142c6a007eea416b75f3592463422dc 505 PANTHER PTHR13847:SF214 7 447 6.5E-198 T 13-09-2016 THL1_RS23845 1142c6a007eea416b75f3592463422dc 505 PANTHER PTHR13847 7 447 6.5E-198 T 13-09-2016 THL1_RS23845 1142c6a007eea416b75f3592463422dc 505 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 5 494 51.194 T 13-09-2016 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254|UniPathway: UPA00223 THL1_RS02950 e1a12c862d056dba8dfdd7e36f48132c 158 Gene3D G3DSA:2.40.50.180 45 66 1.7E-4 T 13-09-2016 THL1_RS02950 e1a12c862d056dba8dfdd7e36f48132c 158 PANTHER PTHR22617 1 152 1.6E-22 T 13-09-2016 THL1_RS02950 e1a12c862d056dba8dfdd7e36f48132c 158 SUPERFAMILY SSF50341 6 139 8.5E-24 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS02950 e1a12c862d056dba8dfdd7e36f48132c 158 Pfam PF01584 CheW-like domain 8 139 5.0E-21 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS02950 e1a12c862d056dba8dfdd7e36f48132c 158 SMART SM00260 1 136 1.2E-11 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS25120 ef1639147b3e9bfc75ef9e8b98acefe3 154 SUPERFAMILY SSF47240 1 153 5.08E-44 T 13-09-2016 IPR009078 Ferritin-like superfamily THL1_RS25120 ef1639147b3e9bfc75ef9e8b98acefe3 154 PIRSF PIRSF002560 1 154 1.0E-61 T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS25120 ef1639147b3e9bfc75ef9e8b98acefe3 154 PRINTS PR00601 Bacterioferritin signature 44 64 1.6E-42 T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS25120 ef1639147b3e9bfc75ef9e8b98acefe3 154 PRINTS PR00601 Bacterioferritin signature 106 126 1.6E-42 T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS25120 ef1639147b3e9bfc75ef9e8b98acefe3 154 PRINTS PR00601 Bacterioferritin signature 128 149 1.6E-42 T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS25120 ef1639147b3e9bfc75ef9e8b98acefe3 154 PRINTS PR00601 Bacterioferritin signature 3 22 1.6E-42 T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS25120 ef1639147b3e9bfc75ef9e8b98acefe3 154 PRINTS PR00601 Bacterioferritin signature 85 105 1.6E-42 T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS25120 ef1639147b3e9bfc75ef9e8b98acefe3 154 PRINTS PR00601 Bacterioferritin signature 23 43 1.6E-42 T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS25120 ef1639147b3e9bfc75ef9e8b98acefe3 154 Pfam PF00210 Ferritin-like domain 9 144 1.0E-35 T 13-09-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 THL1_RS25120 ef1639147b3e9bfc75ef9e8b98acefe3 154 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS25120 ef1639147b3e9bfc75ef9e8b98acefe3 154 TIGRFAM TIGR00754 bfr: bacterioferritin 1 153 3.5E-47 T 13-09-2016 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THL1_RS25120 ef1639147b3e9bfc75ef9e8b98acefe3 154 Gene3D G3DSA:1.20.1260.10 1 153 2.9E-54 T 13-09-2016 IPR012347 Ferritin-related THL1_RS25120 ef1639147b3e9bfc75ef9e8b98acefe3 154 PANTHER PTHR30295 1 153 3.7E-90 T 13-09-2016 THL1_RS25120 ef1639147b3e9bfc75ef9e8b98acefe3 154 PANTHER PTHR30295:SF9 1 153 3.7E-90 T 13-09-2016 THL1_RS08025 46055a2b159ebc46eab31a453834a567 240 PIRSF PIRSF000851 1 239 2.3E-84 T 13-09-2016 IPR026027 Phosphatidylcholine synthase Pcs KEGG: 00564+2.7.8.24|MetaCyc: PWY-6826 THL1_RS08025 46055a2b159ebc46eab31a453834a567 240 Pfam PF01066 CDP-alcohol phosphatidyltransferase 16 68 3.5E-7 T 13-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THL1_RS21220 02a94c7ca81c5e348a2c06bfb1658d2a 232 PANTHER PTHR30450:SF4 1 232 2.3E-159 T 13-09-2016 THL1_RS21220 02a94c7ca81c5e348a2c06bfb1658d2a 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 222 2.7E-15 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS21220 02a94c7ca81c5e348a2c06bfb1658d2a 232 Gene3D G3DSA:1.10.3720.10 12 222 2.6E-39 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS21220 02a94c7ca81c5e348a2c06bfb1658d2a 232 SUPERFAMILY SSF161098 13 209 1.7E-38 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS21220 02a94c7ca81c5e348a2c06bfb1658d2a 232 PANTHER PTHR30450 1 232 2.3E-159 T 13-09-2016 THL1_RS21220 02a94c7ca81c5e348a2c06bfb1658d2a 232 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 117 8.5E-22 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS18380 5ef1b60529768c4de1f3d5cef83db406 595 PANTHER PTHR13943 137 580 1.6E-198 T 13-09-2016 THL1_RS18380 5ef1b60529768c4de1f3d5cef83db406 595 PANTHER PTHR13943:SF48 41 114 1.6E-198 T 13-09-2016 THL1_RS18380 5ef1b60529768c4de1f3d5cef83db406 595 PANTHER PTHR13943:SF48 137 580 1.6E-198 T 13-09-2016 THL1_RS18380 5ef1b60529768c4de1f3d5cef83db406 595 Pfam PF07287 Protein of unknown function (DUF1446) 7 346 2.2E-124 T 13-09-2016 IPR010839 Protein of unknown function DUF1446 THL1_RS18380 5ef1b60529768c4de1f3d5cef83db406 595 PANTHER PTHR13943 41 114 1.6E-198 T 13-09-2016 THL1_RS23645 26fa4d1de4af12608d4335f32723273a 369 PANTHER PTHR22893:SF9 318 357 2.1E-211 T 13-09-2016 THL1_RS23645 26fa4d1de4af12608d4335f32723273a 369 PANTHER PTHR22893:SF9 8 299 2.1E-211 T 13-09-2016 THL1_RS23645 26fa4d1de4af12608d4335f32723273a 369 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 354 3.4E-73 T 13-09-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 THL1_RS23645 26fa4d1de4af12608d4335f32723273a 369 PANTHER PTHR22893 318 357 2.1E-211 T 13-09-2016 THL1_RS23645 26fa4d1de4af12608d4335f32723273a 369 PANTHER PTHR22893 8 299 2.1E-211 T 13-09-2016 THL1_RS23645 26fa4d1de4af12608d4335f32723273a 369 Gene3D G3DSA:3.20.20.70 3 357 5.2E-108 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS23645 26fa4d1de4af12608d4335f32723273a 369 SUPERFAMILY SSF51395 4 353 3.1E-102 T 13-09-2016 THL1_RS10315 cf8a338a04a8e9674ff12dcd207d9b5c 163 Pfam PF14316 Domain of unknown function (DUF4381) 6 161 9.0E-42 T 13-09-2016 IPR025489 Protein of unknown function (DUF4381 THL1_RS27370 60baeb8659cf240dc5fd4615aa6de616 464 Gene3D G3DSA:1.25.40.10 204 246 1.7E-5 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS27370 60baeb8659cf240dc5fd4615aa6de616 464 Gene3D G3DSA:1.25.40.10 30 86 1.7E-5 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS27370 60baeb8659cf240dc5fd4615aa6de616 464 SUPERFAMILY SSF48452 36 101 6.01E-5 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS27370 60baeb8659cf240dc5fd4615aa6de616 464 SUPERFAMILY SSF48452 208 251 6.01E-5 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS25415 98d2744d566c1b7193cc4a9c1c4d5530 454 PANTHER PTHR11206:SF94 6 449 1.4E-123 T 13-09-2016 THL1_RS25415 98d2744d566c1b7193cc4a9c1c4d5530 454 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 421 7.3E-69 T 13-09-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 THL1_RS25415 98d2744d566c1b7193cc4a9c1c4d5530 454 Pfam PF01554 MatE 23 188 8.6E-21 T 13-09-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 THL1_RS25415 98d2744d566c1b7193cc4a9c1c4d5530 454 Pfam PF01554 MatE 253 410 1.0E-12 T 13-09-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 THL1_RS25415 98d2744d566c1b7193cc4a9c1c4d5530 454 PANTHER PTHR11206 6 449 1.4E-123 T 13-09-2016 THL1_RS09865 b8ab57cfd14f2703a031a93019a14bfd 652 PANTHER PTHR10366 282 437 3.3E-126 T 13-09-2016 THL1_RS09865 b8ab57cfd14f2703a031a93019a14bfd 652 PANTHER PTHR10366:SF256 282 437 3.3E-126 T 13-09-2016 THL1_RS09865 b8ab57cfd14f2703a031a93019a14bfd 652 Gene3D G3DSA:3.40.50.720 140 225 1.7E-13 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS09865 b8ab57cfd14f2703a031a93019a14bfd 652 Gene3D G3DSA:3.90.25.10 482 566 8.0E-8 T 13-09-2016 THL1_RS09865 b8ab57cfd14f2703a031a93019a14bfd 652 SUPERFAMILY SSF53335 102 328 2.99E-17 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS09865 b8ab57cfd14f2703a031a93019a14bfd 652 PANTHER PTHR10366:SF256 453 574 3.3E-126 T 13-09-2016 THL1_RS09865 b8ab57cfd14f2703a031a93019a14bfd 652 Gene3D G3DSA:3.40.50.720 282 481 1.7E-41 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS09865 b8ab57cfd14f2703a031a93019a14bfd 652 Pfam PF13727 CoA-binding domain 54 238 2.6E-7 T 13-09-2016 THL1_RS09865 b8ab57cfd14f2703a031a93019a14bfd 652 Pfam PF02719 Polysaccharide biosynthesis protein 283 590 1.3E-127 T 13-09-2016 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain THL1_RS09865 b8ab57cfd14f2703a031a93019a14bfd 652 SUPERFAMILY SSF51735 281 568 2.61E-51 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS09865 b8ab57cfd14f2703a031a93019a14bfd 652 PANTHER PTHR10366 453 574 3.3E-126 T 13-09-2016 THL1_RS06385 a557e45bc6f30b3bed212ce1386ba8f3 385 PANTHER PTHR10443 127 382 1.7E-51 T 13-09-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 THL1_RS06385 a557e45bc6f30b3bed212ce1386ba8f3 385 PANTHER PTHR10443 59 100 1.7E-51 T 13-09-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 THL1_RS06385 a557e45bc6f30b3bed212ce1386ba8f3 385 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 48 380 2.1E-69 T 13-09-2016 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533 THL1_RS06385 a557e45bc6f30b3bed212ce1386ba8f3 385 Gene3D G3DSA:3.20.20.140 38 382 2.4E-87 T 13-09-2016 THL1_RS06385 a557e45bc6f30b3bed212ce1386ba8f3 385 SUPERFAMILY SSF51556 42 383 6.81E-74 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS19735 99438967b9734079cd312d86e5d67a87 276 PANTHER PTHR30465 15 264 3.3E-62 T 13-09-2016 THL1_RS19735 99438967b9734079cd312d86e5d67a87 276 SUPERFAMILY SSF161098 69 256 4.97E-21 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS19735 99438967b9734079cd312d86e5d67a87 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 266 2.1E-27 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS19735 99438967b9734079cd312d86e5d67a87 276 Gene3D G3DSA:1.10.3720.10 65 267 6.6E-22 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS19735 99438967b9734079cd312d86e5d67a87 276 PANTHER PTHR30465:SF10 15 264 3.3E-62 T 13-09-2016 THL1_RS05240 e16e6fc14bccd4476e411257fd9c7211 528 Gene3D G3DSA:3.10.105.10 299 498 1.1E-60 T 13-09-2016 THL1_RS05240 e16e6fc14bccd4476e411257fd9c7211 528 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 65 445 5.1E-94 T 13-09-2016 IPR000914 Solute-binding protein family 5 domain THL1_RS05240 e16e6fc14bccd4476e411257fd9c7211 528 PANTHER PTHR30290 16 528 3.2E-198 T 13-09-2016 THL1_RS05240 e16e6fc14bccd4476e411257fd9c7211 528 Gene3D G3DSA:3.40.190.10 201 298 1.8E-39 T 13-09-2016 THL1_RS05240 e16e6fc14bccd4476e411257fd9c7211 528 SUPERFAMILY SSF53850 21 524 4.85E-148 T 13-09-2016 THL1_RS05240 e16e6fc14bccd4476e411257fd9c7211 528 PANTHER PTHR30290:SF14 16 528 3.2E-198 T 13-09-2016 THL1_RS05240 e16e6fc14bccd4476e411257fd9c7211 528 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 70 92 - T 13-09-2016 IPR023765 Solute-binding protein family 5, conserved site THL1_RS05240 e16e6fc14bccd4476e411257fd9c7211 528 PIRSF PIRSF002741 15 527 4.1E-109 T 13-09-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 THL1_RS05240 e16e6fc14bccd4476e411257fd9c7211 528 Gene3D G3DSA:3.90.76.10 30 200 6.6E-45 T 13-09-2016 THL1_RS04535 88bf078dd71aa3a45692fc097956d81a 303 PANTHER PTHR30193 4 302 3.7E-88 T 13-09-2016 THL1_RS04535 88bf078dd71aa3a45692fc097956d81a 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 287 2.9E-17 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS04535 88bf078dd71aa3a45692fc097956d81a 303 Gene3D G3DSA:1.10.3720.10 25 287 3.4E-47 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS04535 88bf078dd71aa3a45692fc097956d81a 303 SUPERFAMILY SSF161098 27 293 5.14E-50 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS04535 88bf078dd71aa3a45692fc097956d81a 303 PANTHER PTHR30193:SF10 4 302 3.7E-88 T 13-09-2016 THL1_RS27450 6ed6bafd8814b984d4b6b3ad00719fa2 248 PANTHER PTHR26402 1 121 5.1E-44 T 13-09-2016 THL1_RS27450 6ed6bafd8814b984d4b6b3ad00719fa2 248 SMART SM00448 1 113 8.4E-32 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS27450 6ed6bafd8814b984d4b6b3ad00719fa2 248 Gene3D G3DSA:2.40.50.40 141 204 4.0E-11 T 13-09-2016 THL1_RS27450 6ed6bafd8814b984d4b6b3ad00719fa2 248 Pfam PF00072 Response regulator receiver domain 3 113 1.4E-27 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS27450 6ed6bafd8814b984d4b6b3ad00719fa2 248 PANTHER PTHR26402:SF579 1 121 5.1E-44 T 13-09-2016 THL1_RS27450 6ed6bafd8814b984d4b6b3ad00719fa2 248 Gene3D G3DSA:3.40.50.2300 1 121 6.8E-34 T 13-09-2016 THL1_RS27450 6ed6bafd8814b984d4b6b3ad00719fa2 248 Pfam PF04397 LytTr DNA-binding domain 149 245 1.7E-21 T 13-09-2016 IPR007492 LytTR DNA-binding domain GO:0003677 THL1_RS27450 6ed6bafd8814b984d4b6b3ad00719fa2 248 SMART SM00850 148 246 8.2E-24 T 13-09-2016 IPR007492 LytTR DNA-binding domain GO:0003677 THL1_RS27450 6ed6bafd8814b984d4b6b3ad00719fa2 248 SUPERFAMILY SSF52172 1 123 3.56E-34 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS20495 db5c7bbb75db2a41eba9d59b8b8e888d 369 Gene3D G3DSA:2.130.10.10 56 323 1.4E-24 T 13-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THL1_RS20495 db5c7bbb75db2a41eba9d59b8b8e888d 369 Pfam PF14870 Photosynthesis system II assembly factor YCF48 60 121 2.2E-8 T 13-09-2016 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain THL1_RS20495 db5c7bbb75db2a41eba9d59b8b8e888d 369 Pfam PF14870 Photosynthesis system II assembly factor YCF48 166 312 3.1E-10 T 13-09-2016 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain THL1_RS20495 db5c7bbb75db2a41eba9d59b8b8e888d 369 SUPERFAMILY SSF110296 55 130 9.42E-33 T 13-09-2016 THL1_RS20495 db5c7bbb75db2a41eba9d59b8b8e888d 369 SUPERFAMILY SSF110296 166 331 9.42E-33 T 13-09-2016 THL1_RS17845 5a51ee4452a1f13cca745aefa5bd395b 500 PANTHER PTHR10283 12 168 3.8E-250 T 13-09-2016 THL1_RS17845 5a51ee4452a1f13cca745aefa5bd395b 500 Pfam PF06450 Bacterial Na+/H+ antiporter B (NhaB) 1 497 1.3E-231 T 13-09-2016 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 THL1_RS17845 5a51ee4452a1f13cca745aefa5bd395b 500 PANTHER PTHR10283:SF93 12 168 3.8E-250 T 13-09-2016 THL1_RS17845 5a51ee4452a1f13cca745aefa5bd395b 500 PANTHER PTHR10283:SF93 198 500 3.8E-250 T 13-09-2016 THL1_RS17845 5a51ee4452a1f13cca745aefa5bd395b 500 Hamap MF_01599 Na(+)/H(+) antiporter NhaB [nhaB]. 1 500 318.305 T 13-09-2016 IPR004671 Na+/H+ antiporter NhaB GO:0006814|GO:0015385|GO:0016021 THL1_RS17845 5a51ee4452a1f13cca745aefa5bd395b 500 PANTHER PTHR10283 198 500 3.8E-250 T 13-09-2016 THL1_RS27855 7b9c441bf452f5fc3d4cc2db4c244963 213 PANTHER PTHR19278:SF36 1 213 5.1E-134 T 13-09-2016 THL1_RS27855 7b9c441bf452f5fc3d4cc2db4c244963 213 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 11 186 3.4E-63 T 13-09-2016 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS27855 7b9c441bf452f5fc3d4cc2db4c244963 213 PANTHER PTHR19278 1 213 5.1E-134 T 13-09-2016 THL1_RS27855 7b9c441bf452f5fc3d4cc2db4c244963 213 SUPERFAMILY SSF53271 1 205 3.59E-49 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS27855 7b9c441bf452f5fc3d4cc2db4c244963 213 Gene3D G3DSA:3.40.50.2020 7 212 1.1E-80 T 13-09-2016 IPR029057 Phosphoribosyltransferase-like THL1_RS27855 7b9c441bf452f5fc3d4cc2db4c244963 213 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 213 35.075 T 13-09-2016 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 THL1_RS27855 7b9c441bf452f5fc3d4cc2db4c244963 213 Pfam PF00156 Phosphoribosyl transferase domain 44 158 1.2E-12 T 13-09-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 THL1_RS12260 af3d964099d11a414ecd2382096b4c99 166 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 16 159 6.5E-33 T 13-09-2016 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 THL1_RS12260 af3d964099d11a414ecd2382096b4c99 166 PANTHER PTHR33269 1 166 4.7E-80 T 13-09-2016 THL1_RS12260 af3d964099d11a414ecd2382096b4c99 166 PANTHER PTHR33269:SF2 1 166 4.7E-80 T 13-09-2016 THL1_RS13625 1786f1b9134bae86dca3815ae8ae5f17 265 Hamap MF_01830 UPF0317 protein . 13 264 50.214 T 13-09-2016 IPR016938 Uncharacterised protein family UPF0317 THL1_RS13625 1786f1b9134bae86dca3815ae8ae5f17 265 PIRSF PIRSF029755 2 265 2.1E-115 T 13-09-2016 IPR016938 Uncharacterised protein family UPF0317 THL1_RS13625 1786f1b9134bae86dca3815ae8ae5f17 265 Gene3D G3DSA:3.40.1640.10 6 169 5.8E-60 T 13-09-2016 THL1_RS13625 1786f1b9134bae86dca3815ae8ae5f17 265 Pfam PF07286 Protein of unknown function (DUF1445) 117 259 1.3E-62 T 13-09-2016 IPR009906 Protein of unknown function DUF1445 THL1_RS13625 1786f1b9134bae86dca3815ae8ae5f17 265 PANTHER PTHR32022 1 262 6.6E-149 T 13-09-2016 THL1_RS13625 1786f1b9134bae86dca3815ae8ae5f17 265 SUPERFAMILY SSF160920 9 259 2.62E-104 T 13-09-2016 THL1_RS00915 78c47f77ecf362640740de520e56aca2 320 PANTHER PTHR30024 1 314 2.4E-141 T 13-09-2016 THL1_RS00915 78c47f77ecf362640740de520e56aca2 320 SMART SM00062 30 242 5.5E-32 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS00915 78c47f77ecf362640740de520e56aca2 320 Pfam PF09084 NMT1/THI5 like 55 249 6.0E-17 T 13-09-2016 IPR015168 SsuA/THI5-like THL1_RS00915 78c47f77ecf362640740de520e56aca2 320 PANTHER PTHR30024:SF11 1 314 2.4E-141 T 13-09-2016 THL1_RS00915 78c47f77ecf362640740de520e56aca2 320 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 31 312 5.8E-75 T 13-09-2016 IPR010067 Aliphatic sulfonates-binding protein GO:0006790|GO:0006810|GO:0016020 THL1_RS00915 78c47f77ecf362640740de520e56aca2 320 SUPERFAMILY SSF53850 29 255 7.35E-52 T 13-09-2016 THL1_RS00915 78c47f77ecf362640740de520e56aca2 320 Gene3D G3DSA:3.40.190.10 112 235 7.2E-31 T 13-09-2016 THL1_RS17230 dd412068979a4bb47955de5e366ead84 321 Pfam PF14870 Photosynthesis system II assembly factor YCF48 76 160 1.2E-12 T 13-09-2016 IPR028203 Photosynthesis system II assembly factor Ycf48/Hcf136-like domain THL1_RS17230 dd412068979a4bb47955de5e366ead84 321 Gene3D G3DSA:2.130.10.140 156 298 1.1E-18 T 13-09-2016 THL1_RS17230 dd412068979a4bb47955de5e366ead84 321 Gene3D G3DSA:2.130.10.140 50 155 1.8E-13 T 13-09-2016 THL1_RS17230 dd412068979a4bb47955de5e366ead84 321 SUPERFAMILY SSF110296 42 291 9.94E-47 T 13-09-2016 THL1_RS15800 0c778aaed45cabbd24dedab836347c8a 286 PANTHER PTHR30389 1 283 1.8E-164 T 13-09-2016 THL1_RS15800 0c778aaed45cabbd24dedab836347c8a 286 PANTHER PTHR30389:SF3 1 283 1.8E-164 T 13-09-2016 THL1_RS15800 0c778aaed45cabbd24dedab836347c8a 286 Pfam PF05681 Fumarate hydratase (Fumerase) 3 268 1.0E-72 T 13-09-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 THL1_RS15800 0c778aaed45cabbd24dedab836347c8a 286 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 3 269 1.1E-94 T 13-09-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 PANTHER PTHR19370 17 244 4.5E-56 T 13-09-2016 THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 SUPERFAMILY SSF54292 234 345 1.13E-25 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 Gene3D G3DSA:2.40.30.10 15 108 1.1E-25 T 13-09-2016 THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 48 58 3.4E-8 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 67 74 3.4E-8 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 150 159 3.4E-8 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 210 218 3.4E-8 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 126 145 3.4E-8 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 PRINTS PR00409 Phthalate dioxygenase reductase family signature 104 118 8.4E-10 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 PRINTS PR00409 Phthalate dioxygenase reductase family signature 210 218 8.4E-10 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 PRINTS PR00409 Phthalate dioxygenase reductase family signature 126 145 8.4E-10 T 13-09-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 Gene3D G3DSA:3.10.20.30 237 345 2.7E-28 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 SUPERFAMILY SSF63380 13 120 3.25E-27 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 299 307 - T 13-09-2016 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 Pfam PF00970 Oxidoreductase FAD-binding domain 19 117 7.7E-13 T 13-09-2016 IPR008333 Oxidoreductase, FAD-binding domain THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 Gene3D G3DSA:3.40.50.80 109 236 2.6E-34 T 13-09-2016 THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 SUPERFAMILY SSF52343 106 240 9.17E-33 T 13-09-2016 THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 Pfam PF00175 Oxidoreductase NAD-binding domain 128 224 2.1E-15 T 13-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THL1_RS21785 66b3c1d3102184d2af3effa2c3f47804 352 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 268 341 7.2E-17 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS15795 e2d1d7ac1c1f82e903aafb02d36eaedc 202 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 13 178 4.0E-67 T 13-09-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 THL1_RS15795 e2d1d7ac1c1f82e903aafb02d36eaedc 202 Gene3D G3DSA:3.20.130.10 2 178 2.8E-70 T 13-09-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 THL1_RS15795 e2d1d7ac1c1f82e903aafb02d36eaedc 202 PANTHER PTHR30389 1 198 4.0E-92 T 13-09-2016 THL1_RS15795 e2d1d7ac1c1f82e903aafb02d36eaedc 202 SUPERFAMILY SSF117457 3 177 1.05E-59 T 13-09-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 THL1_RS15795 e2d1d7ac1c1f82e903aafb02d36eaedc 202 Pfam PF05683 Fumarase C-terminus 9 178 1.3E-41 T 13-09-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 THL1_RS02755 e2a4f780a64e730625d91901769a3053 334 SUPERFAMILY SSF52980 26 216 1.5E-30 T 13-09-2016 IPR011335 Restriction endonuclease type II-like THL1_RS02755 e2a4f780a64e730625d91901769a3053 334 Gene3D G3DSA:3.90.320.10 24 213 2.9E-29 T 13-09-2016 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 THL1_RS02755 e2a4f780a64e730625d91901769a3053 334 Pfam PF09588 YqaJ-like viral recombinase domain 29 171 4.5E-36 T 13-09-2016 IPR019080 YqaJ viral recombinase THL1_RS02755 e2a4f780a64e730625d91901769a3053 334 TIGRFAM TIGR03033 phage_rel_nuc: putative phage-type endonuclease 23 182 1.3E-51 T 13-09-2016 IPR017482 Putative phage-type endonuclease THL1_RS19800 993570de093c92445db10f728dfb817f 257 Gene3D G3DSA:3.40.190.10 203 240 2.8E-10 T 13-09-2016 THL1_RS19800 993570de093c92445db10f728dfb817f 257 Gene3D G3DSA:3.40.190.10 28 105 2.8E-10 T 13-09-2016 THL1_RS19800 993570de093c92445db10f728dfb817f 257 SUPERFAMILY SSF53850 24 240 3.03E-30 T 13-09-2016 THL1_RS19800 993570de093c92445db10f728dfb817f 257 PANTHER PTHR35936 1 253 5.1E-26 T 13-09-2016 THL1_RS19800 993570de093c92445db10f728dfb817f 257 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 237 1.3E-13 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS14030 fefbf3991d7c95d639fd9ff1f6e83836 278 Gene3D G3DSA:1.10.3720.10 11 268 7.7E-47 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS14030 fefbf3991d7c95d639fd9ff1f6e83836 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 267 3.7E-13 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS14030 fefbf3991d7c95d639fd9ff1f6e83836 278 PANTHER PTHR30193 1 272 1.7E-65 T 13-09-2016 THL1_RS14030 fefbf3991d7c95d639fd9ff1f6e83836 278 SUPERFAMILY SSF161098 11 271 9.16E-51 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS14030 fefbf3991d7c95d639fd9ff1f6e83836 278 PANTHER PTHR30193:SF10 1 272 1.7E-65 T 13-09-2016 THL1_RS27240 8b70924ed328ad3e743e906046ab7923 406 Gene3D G3DSA:3.50.50.60 6 184 2.0E-49 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27240 8b70924ed328ad3e743e906046ab7923 406 Gene3D G3DSA:3.50.50.60 273 361 2.0E-49 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27240 8b70924ed328ad3e743e906046ab7923 406 SUPERFAMILY SSF51905 6 179 7.38E-62 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27240 8b70924ed328ad3e743e906046ab7923 406 SUPERFAMILY SSF51905 272 389 7.38E-62 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS27240 8b70924ed328ad3e743e906046ab7923 406 Pfam PF01494 FAD binding domain 5 351 2.3E-28 T 13-09-2016 IPR002938 FAD-binding domain GO:0071949 THL1_RS27240 8b70924ed328ad3e743e906046ab7923 406 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 299 312 - T 13-09-2016 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 UniPathway: UPA00232 THL1_RS27240 8b70924ed328ad3e743e906046ab7923 406 PANTHER PTHR13789:SF5 4 396 1.0E-143 T 13-09-2016 THL1_RS27240 8b70924ed328ad3e743e906046ab7923 406 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 6 395 4.1E-137 T 13-09-2016 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 UniPathway: UPA00232 THL1_RS27240 8b70924ed328ad3e743e906046ab7923 406 PANTHER PTHR13789 4 396 1.0E-143 T 13-09-2016 THL1_RS27240 8b70924ed328ad3e743e906046ab7923 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 5.5E-18 T 13-09-2016 THL1_RS27240 8b70924ed328ad3e743e906046ab7923 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 5.5E-18 T 13-09-2016 THL1_RS27240 8b70924ed328ad3e743e906046ab7923 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 158 173 5.5E-18 T 13-09-2016 THL1_RS27240 8b70924ed328ad3e743e906046ab7923 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 5.5E-18 T 13-09-2016 THL1_RS08160 3bd84693e423475aa015db2f8073001f 92 PANTHER PTHR38775:SF1 2 92 8.3E-21 T 13-09-2016 THL1_RS08160 3bd84693e423475aa015db2f8073001f 92 PANTHER PTHR38775 2 92 8.3E-21 T 13-09-2016 THL1_RS08160 3bd84693e423475aa015db2f8073001f 92 Pfam PF06611 Protein of unknown function (DUF1145) 4 59 1.2E-18 T 13-09-2016 IPR009525 Protein of unknown function DUF1145 THL1_RS04365 32de7933bb8f1ee39db7354bde894a6b 549 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 403 422 - T 13-09-2016 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 THL1_RS04365 32de7933bb8f1ee39db7354bde894a6b 549 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 182 278 4.4E-12 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS04365 32de7933bb8f1ee39db7354bde894a6b 549 Gene3D G3DSA:1.20.140.10 284 449 9.1E-39 T 13-09-2016 THL1_RS04365 32de7933bb8f1ee39db7354bde894a6b 549 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 290 444 3.1E-28 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS04365 32de7933bb8f1ee39db7354bde894a6b 549 SUPERFAMILY SSF47203 295 447 5.48E-40 T 13-09-2016 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THL1_RS04365 32de7933bb8f1ee39db7354bde894a6b 549 SUPERFAMILY SSF56645 63 299 1.0E-36 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS04365 32de7933bb8f1ee39db7354bde894a6b 549 Gene3D G3DSA:2.40.110.10 182 283 8.2E-18 T 13-09-2016 THL1_RS04365 32de7933bb8f1ee39db7354bde894a6b 549 PANTHER PTHR10909:SF289 63 464 1.5E-207 T 13-09-2016 THL1_RS04365 32de7933bb8f1ee39db7354bde894a6b 549 PANTHER PTHR10909 63 464 1.5E-207 T 13-09-2016 THL1_RS09720 c1e98fee66865afc785bbf11104623bc 346 Pfam PF11927 Protein of unknown function (DUF3445) 52 293 6.3E-49 T 13-09-2016 IPR021848 Protein of unknown function DUF3445 THL1_RS00405 f7543bf4d6ad270e83392688439cc468 197 PANTHER PTHR33508:SF4 1 196 2.6E-76 T 13-09-2016 THL1_RS00405 f7543bf4d6ad270e83392688439cc468 197 PANTHER PTHR33508 1 196 2.6E-76 T 13-09-2016 THL1_RS00405 f7543bf4d6ad270e83392688439cc468 197 Pfam PF01914 MarC family integral membrane protein 3 192 6.7E-46 T 13-09-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 THL1_RS08975 1134d38f4b4cdd3cfdd88241955211b2 223 PANTHER PTHR30037:SF3 174 206 1.6E-113 T 13-09-2016 THL1_RS08975 1134d38f4b4cdd3cfdd88241955211b2 223 PANTHER PTHR30037 174 206 1.6E-113 T 13-09-2016 THL1_RS08975 1134d38f4b4cdd3cfdd88241955211b2 223 Pfam PF03352 Methyladenine glycosylase 38 130 7.3E-18 T 13-09-2016 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 THL1_RS08975 1134d38f4b4cdd3cfdd88241955211b2 223 SUPERFAMILY SSF48150 36 182 3.37E-38 T 13-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 THL1_RS08975 1134d38f4b4cdd3cfdd88241955211b2 223 PANTHER PTHR30037 1 156 1.6E-113 T 13-09-2016 THL1_RS08975 1134d38f4b4cdd3cfdd88241955211b2 223 PANTHER PTHR30037:SF3 1 156 1.6E-113 T 13-09-2016 THL1_RS08975 1134d38f4b4cdd3cfdd88241955211b2 223 Gene3D G3DSA:1.10.340.30 36 147 1.1E-26 T 13-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 THL1_RS19840 484a43fffcade3df7eefaf4c480ea0d9 310 SUPERFAMILY SSF50341 16 156 1.28E-35 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS19840 484a43fffcade3df7eefaf4c480ea0d9 310 Gene3D G3DSA:2.40.50.180 60 96 1.1E-4 T 13-09-2016 THL1_RS19840 484a43fffcade3df7eefaf4c480ea0d9 310 SMART SM00260 17 153 1.0E-19 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS19840 484a43fffcade3df7eefaf4c480ea0d9 310 PANTHER PTHR22617 1 169 2.5E-100 T 13-09-2016 THL1_RS19840 484a43fffcade3df7eefaf4c480ea0d9 310 Pfam PF01584 CheW-like domain 21 156 1.4E-34 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS19840 484a43fffcade3df7eefaf4c480ea0d9 310 SUPERFAMILY SSF52172 179 304 1.71E-24 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS19840 484a43fffcade3df7eefaf4c480ea0d9 310 PIRSF PIRSF002867 1 308 3.7E-107 T 13-09-2016 IPR024181 Chemotaxis response regulator CheV THL1_RS19840 484a43fffcade3df7eefaf4c480ea0d9 310 Gene3D G3DSA:2.30.30.40 97 144 3.1E-6 T 13-09-2016 THL1_RS19840 484a43fffcade3df7eefaf4c480ea0d9 310 PANTHER PTHR22617:SF30 1 169 2.5E-100 T 13-09-2016 THL1_RS19840 484a43fffcade3df7eefaf4c480ea0d9 310 Gene3D G3DSA:3.40.50.2300 178 302 7.4E-27 T 13-09-2016 THL1_RS19840 484a43fffcade3df7eefaf4c480ea0d9 310 Pfam PF00072 Response regulator receiver domain 181 300 5.5E-18 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS19840 484a43fffcade3df7eefaf4c480ea0d9 310 SMART SM00448 179 300 4.3E-18 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS06150 a5d8e6053a22e018e9407b89c01218bc 447 PANTHER PTHR30258:SF3 7 389 2.4E-100 T 13-09-2016 THL1_RS06150 a5d8e6053a22e018e9407b89c01218bc 447 Gene3D G3DSA:3.40.50.300 184 388 5.8E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06150 a5d8e6053a22e018e9407b89c01218bc 447 PANTHER PTHR30258 7 389 2.4E-100 T 13-09-2016 THL1_RS06150 a5d8e6053a22e018e9407b89c01218bc 447 Gene3D G3DSA:3.30.450.90 79 175 5.0E-29 T 13-09-2016 THL1_RS06150 a5d8e6053a22e018e9407b89c01218bc 447 SUPERFAMILY SSF52540 70 364 9.5E-50 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS06150 a5d8e6053a22e018e9407b89c01218bc 447 Pfam PF00437 Type II/IV secretion system protein 82 357 1.4E-70 T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS23270 4c949992011e1466b0ddd9ce79b04e08 371 PANTHER PTHR22935:SF10 20 369 1.6E-66 T 13-09-2016 THL1_RS23270 4c949992011e1466b0ddd9ce79b04e08 371 SUPERFAMILY SSF56601 9 361 8.68E-75 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS23270 4c949992011e1466b0ddd9ce79b04e08 371 Pfam PF00144 Beta-lactamase 57 349 1.2E-35 T 13-09-2016 IPR001466 Beta-lactamase-related THL1_RS23270 4c949992011e1466b0ddd9ce79b04e08 371 Gene3D G3DSA:3.40.710.10 59 366 1.5E-41 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS23270 4c949992011e1466b0ddd9ce79b04e08 371 PANTHER PTHR22935 20 369 1.6E-66 T 13-09-2016 THL1_RS13155 a70912427dc6ca12fbd9711d4d88df5d 493 PANTHER PTHR30097:SF3 46 413 4.6E-84 T 13-09-2016 THL1_RS13155 a70912427dc6ca12fbd9711d4d88df5d 493 SUPERFAMILY SSF111369 129 326 3.79E-13 T 13-09-2016 THL1_RS13155 a70912427dc6ca12fbd9711d4d88df5d 493 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 216 397 2.6E-39 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS13155 a70912427dc6ca12fbd9711d4d88df5d 493 PANTHER PTHR30097 46 413 4.6E-84 T 13-09-2016 THL1_RS13155 a70912427dc6ca12fbd9711d4d88df5d 493 Gene3D G3DSA:2.40.50.100 215 246 7.6E-6 T 13-09-2016 THL1_RS13155 a70912427dc6ca12fbd9711d4d88df5d 493 Gene3D G3DSA:2.40.50.100 131 164 7.6E-6 T 13-09-2016 THL1_RS13155 a70912427dc6ca12fbd9711d4d88df5d 493 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 113 321 2.1E-71 T 13-09-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THL1_RS13155 a70912427dc6ca12fbd9711d4d88df5d 493 Pfam PF11604 Copper binding periplasmic protein CusF 425 487 3.9E-19 T 13-09-2016 IPR021647 Copper binding periplasmic protein CusF THL1_RS13805 0326d87cc891f1122869779e95f3e317 469 PIRSF PIRSF006060 10 469 2.7E-61 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS13805 0326d87cc891f1122869779e95f3e317 469 PANTHER PTHR11785 25 469 1.3E-58 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS13805 0326d87cc891f1122869779e95f3e317 469 Pfam PF13520 Amino acid permease 28 438 3.3E-28 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS17980 e5a40123298533bd77ac5fd6af139ed8 90 Gene3D G3DSA:4.10.520.10 1 90 7.0E-36 T 13-09-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THL1_RS17980 e5a40123298533bd77ac5fd6af139ed8 90 SMART SM00411 1 90 9.4E-43 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS17980 e5a40123298533bd77ac5fd6af139ed8 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 13-09-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 THL1_RS17980 e5a40123298533bd77ac5fd6af139ed8 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 2.6E-19 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS17980 e5a40123298533bd77ac5fd6af139ed8 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 2.6E-19 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS17980 e5a40123298533bd77ac5fd6af139ed8 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 2.6E-19 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS17980 e5a40123298533bd77ac5fd6af139ed8 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 1.6E-32 T 13-09-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 THL1_RS17980 e5a40123298533bd77ac5fd6af139ed8 90 SUPERFAMILY SSF47729 1 90 2.94E-31 T 13-09-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 THL1_RS17980 e5a40123298533bd77ac5fd6af139ed8 90 PANTHER PTHR33175 1 90 8.9E-44 T 13-09-2016 THL1_RS02295 db087b397bb5c670b4b40db2c238d791 518 PIRSF PIRSF000858 1 517 2.1E-231 T 13-09-2016 IPR014388 3-oxoacid CoA-transferase GO:0008410|GO:0046952 THL1_RS02295 db087b397bb5c670b4b40db2c238d791 518 Gene3D G3DSA:3.40.1080.10 1 240 1.3E-72 T 13-09-2016 THL1_RS02295 db087b397bb5c670b4b40db2c238d791 518 Pfam PF01144 Coenzyme A transferase 4 241 1.5E-31 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS02295 db087b397bb5c670b4b40db2c238d791 518 SUPERFAMILY SSF100950 272 515 3.63E-75 T 13-09-2016 THL1_RS02295 db087b397bb5c670b4b40db2c238d791 518 SMART SM00882 278 486 3.2E-4 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS02295 db087b397bb5c670b4b40db2c238d791 518 SMART SM00882 4 241 3.0E-69 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS02295 db087b397bb5c670b4b40db2c238d791 518 PANTHER PTHR13707:SF38 1 505 9.3E-246 T 13-09-2016 THL1_RS02295 db087b397bb5c670b4b40db2c238d791 518 Gene3D G3DSA:3.40.810.20 271 510 3.3E-64 T 13-09-2016 THL1_RS02295 db087b397bb5c670b4b40db2c238d791 518 PANTHER PTHR13707 1 505 9.3E-246 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS02295 db087b397bb5c670b4b40db2c238d791 518 SUPERFAMILY SSF100950 2 257 1.35E-90 T 13-09-2016 THL1_RS13795 43f79c0845f835f0df8bade1039390e8 442 PIRSF PIRSF000521 23 439 5.4E-32 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS13795 43f79c0845f835f0df8bade1039390e8 442 SUPERFAMILY SSF53383 3 434 4.43E-127 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS13795 43f79c0845f835f0df8bade1039390e8 442 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 244 281 - T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS13795 43f79c0845f835f0df8bade1039390e8 442 Gene3D G3DSA:3.40.640.10 57 335 2.5E-87 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS13795 43f79c0845f835f0df8bade1039390e8 442 Pfam PF00202 Aminotransferase class-III 20 433 7.9E-112 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS13795 43f79c0845f835f0df8bade1039390e8 442 Gene3D G3DSA:3.90.1150.10 336 439 1.0E-37 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS13795 43f79c0845f835f0df8bade1039390e8 442 Gene3D G3DSA:3.90.1150.10 3 55 1.0E-37 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS13795 43f79c0845f835f0df8bade1039390e8 442 PANTHER PTHR11986 5 441 2.6E-159 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS22890 98c1048e3b64f1b61292b7bb6e677675 341 Pfam PF00072 Response regulator receiver domain 20 132 5.1E-18 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS22890 98c1048e3b64f1b61292b7bb6e677675 341 SMART SM00448 18 132 8.0E-22 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS22890 98c1048e3b64f1b61292b7bb6e677675 341 SUPERFAMILY SSF55073 175 333 1.18E-45 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS22890 98c1048e3b64f1b61292b7bb6e677675 341 PANTHER PTHR10799:SF750 124 334 3.7E-29 T 13-09-2016 THL1_RS22890 98c1048e3b64f1b61292b7bb6e677675 341 Gene3D G3DSA:3.40.50.2300 16 158 1.0E-27 T 13-09-2016 THL1_RS22890 98c1048e3b64f1b61292b7bb6e677675 341 Pfam PF00990 Diguanylate cyclase, GGDEF domain 171 331 8.5E-49 T 13-09-2016 IPR000160 GGDEF domain THL1_RS22890 98c1048e3b64f1b61292b7bb6e677675 341 SMART SM00267 159 335 4.0E-61 T 13-09-2016 IPR000160 GGDEF domain THL1_RS22890 98c1048e3b64f1b61292b7bb6e677675 341 PANTHER PTHR10799 124 334 3.7E-29 T 13-09-2016 THL1_RS22890 98c1048e3b64f1b61292b7bb6e677675 341 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 166 334 4.4E-50 T 13-09-2016 IPR000160 GGDEF domain THL1_RS22890 98c1048e3b64f1b61292b7bb6e677675 341 SUPERFAMILY SSF52172 13 146 9.53E-29 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS22890 98c1048e3b64f1b61292b7bb6e677675 341 Gene3D G3DSA:3.30.70.270 172 336 6.2E-51 T 13-09-2016 THL1_RS13840 4efdc984930ce8ba44b085e06434aa75 161 Pfam PF11158 Protein of unknown function (DUF2938) 9 155 2.1E-59 T 13-09-2016 IPR021329 Protein of unknown function DUF2938 THL1_RS20445 19dfdb0063365e379a6f5fe9dc4fb9bb 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 13-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THL1_RS20445 19dfdb0063365e379a6f5fe9dc4fb9bb 257 Gene3D G3DSA:3.90.226.10 1 254 2.6E-94 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20445 19dfdb0063365e379a6f5fe9dc4fb9bb 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 254 1.7E-77 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS20445 19dfdb0063365e379a6f5fe9dc4fb9bb 257 PANTHER PTHR11941 1 254 3.4E-115 T 13-09-2016 THL1_RS20445 19dfdb0063365e379a6f5fe9dc4fb9bb 257 SUPERFAMILY SSF52096 2 254 6.15E-86 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS20445 19dfdb0063365e379a6f5fe9dc4fb9bb 257 PANTHER PTHR11941:SF54 1 254 3.4E-115 T 13-09-2016 THL1_RS03985 1c61dcb8eb26a7a44ff0fe12fa697511 249 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 56 227 6.4E-50 T 13-09-2016 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00566 THL1_RS03985 1c61dcb8eb26a7a44ff0fe12fa697511 249 PANTHER PTHR34136 1 247 3.6E-99 T 13-09-2016 THL1_RS03985 1c61dcb8eb26a7a44ff0fe12fa697511 249 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 60 225 2.2E-60 T 13-09-2016 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00566 THL1_RS03985 1c61dcb8eb26a7a44ff0fe12fa697511 249 PANTHER PTHR34136:SF1 1 247 3.6E-99 T 13-09-2016 THL1_RS03615 1359bd0f03262395b320db5fc1e01f32 58 Gene3D G3DSA:3.30.1390.20 1 57 3.0E-26 T 13-09-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain THL1_RS03615 1359bd0f03262395b320db5fc1e01f32 58 Pfam PF00327 Ribosomal protein L30p/L7e 4 52 2.6E-17 T 13-09-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain THL1_RS03615 1359bd0f03262395b320db5fc1e01f32 58 SUPERFAMILY SSF55129 1 57 1.2E-19 T 13-09-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain THL1_RS03615 1359bd0f03262395b320db5fc1e01f32 58 PANTHER PTHR15892 1 57 5.5E-24 T 13-09-2016 THL1_RS03615 1359bd0f03262395b320db5fc1e01f32 58 PIRSF PIRSF002211 1 58 2.6E-23 T 13-09-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 THL1_RS03615 1359bd0f03262395b320db5fc1e01f32 58 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 57 2.0E-19 T 13-09-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 THL1_RS03615 1359bd0f03262395b320db5fc1e01f32 58 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 19.614 T 13-09-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 THL1_RS02130 cf1719695d1ea97e8a63910c26821dc9 148 Gene3D G3DSA:3.40.630.30 4 143 1.2E-26 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS02130 cf1719695d1ea97e8a63910c26821dc9 148 PANTHER PTHR23091 10 145 2.8E-42 T 13-09-2016 THL1_RS02130 cf1719695d1ea97e8a63910c26821dc9 148 PANTHER PTHR23091:SF250 10 145 2.8E-42 T 13-09-2016 THL1_RS02130 cf1719695d1ea97e8a63910c26821dc9 148 Pfam PF00583 Acetyltransferase (GNAT) family 56 134 5.2E-13 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS02130 cf1719695d1ea97e8a63910c26821dc9 148 SUPERFAMILY SSF55729 3 145 1.15E-31 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS12665 b681370114f5b1117254c8466ddd6a08 636 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 441 564 6.4E-9 T 13-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain THL1_RS12665 b681370114f5b1117254c8466ddd6a08 636 Pfam PF01261 Xylose isomerase-like TIM barrel 18 217 2.0E-39 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS12665 b681370114f5b1117254c8466ddd6a08 636 SUPERFAMILY SSF54593 288 622 6.31E-63 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS12665 b681370114f5b1117254c8466ddd6a08 636 PANTHER PTHR12110:SF14 1 275 2.3E-87 T 13-09-2016 THL1_RS12665 b681370114f5b1117254c8466ddd6a08 636 Gene3D G3DSA:3.10.180.10 287 428 7.6E-37 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS12665 b681370114f5b1117254c8466ddd6a08 636 PANTHER PTHR12110 1 275 2.3E-87 T 13-09-2016 THL1_RS12665 b681370114f5b1117254c8466ddd6a08 636 Gene3D G3DSA:3.20.20.150 1 264 7.6E-80 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS12665 b681370114f5b1117254c8466ddd6a08 636 Gene3D G3DSA:3.10.180.10 439 625 1.6E-41 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS12665 b681370114f5b1117254c8466ddd6a08 636 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 295 427 2.5E-34 T 13-09-2016 THL1_RS12665 b681370114f5b1117254c8466ddd6a08 636 SUPERFAMILY SSF51658 1 268 1.38E-77 T 13-09-2016 IPR013022 Xylose isomerase-like, TIM barrel domain THL1_RS25140 be85644bfc5db84a3f99aa1de749966c 93 PIRSF PIRSF028291 1 93 7.7E-26 T 13-09-2016 IPR014543 Uncharacterised conserved protein UCP028291 THL1_RS25140 be85644bfc5db84a3f99aa1de749966c 93 Pfam PF09981 Uncharacterized protein conserved in bacteria (DUF2218) 7 92 2.9E-30 T 13-09-2016 IPR014543 Uncharacterised conserved protein UCP028291 THL1_RS18880 e320b03429a0876e114ee4e1b0aeaea0 244 Gene3D G3DSA:2.60.120.10 14 164 5.1E-32 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS18880 e320b03429a0876e114ee4e1b0aeaea0 244 Pfam PF00027 Cyclic nucleotide-binding domain 45 127 8.1E-15 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS18880 e320b03429a0876e114ee4e1b0aeaea0 244 SUPERFAMILY SSF51206 18 157 1.27E-30 T 13-09-2016 IPR018490 Cyclic nucleotide-binding-like THL1_RS18880 e320b03429a0876e114ee4e1b0aeaea0 244 PANTHER PTHR24567 12 239 1.4E-101 T 13-09-2016 THL1_RS18880 e320b03429a0876e114ee4e1b0aeaea0 244 PANTHER PTHR24567:SF28 12 239 1.4E-101 T 13-09-2016 THL1_RS18880 e320b03429a0876e114ee4e1b0aeaea0 244 SMART SM00100 25 146 9.1E-19 T 13-09-2016 IPR000595 Cyclic nucleotide-binding domain THL1_RS18880 e320b03429a0876e114ee4e1b0aeaea0 244 ProSitePatterns PS00042 Crp-type HTH domain signature. 190 213 - T 13-09-2016 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 THL1_RS18880 e320b03429a0876e114ee4e1b0aeaea0 244 Gene3D G3DSA:1.10.10.10 165 239 8.1E-27 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS18880 e320b03429a0876e114ee4e1b0aeaea0 244 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 204 219 6.9E-11 T 13-09-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THL1_RS18880 e320b03429a0876e114ee4e1b0aeaea0 244 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 188 204 6.9E-11 T 13-09-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THL1_RS18880 e320b03429a0876e114ee4e1b0aeaea0 244 Pfam PF13545 Crp-like helix-turn-helix domain 163 236 1.8E-16 T 13-09-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THL1_RS18880 e320b03429a0876e114ee4e1b0aeaea0 244 SUPERFAMILY SSF46785 161 239 2.46E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS18880 e320b03429a0876e114ee4e1b0aeaea0 244 SMART SM00419 182 230 9.5E-16 T 13-09-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THL1_RS13890 ad26feabd8c8f219e50df0713e410718 350 Pfam PF05853 beta-keto acid cleavage enzyme 15 318 4.0E-65 T 13-09-2016 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00600+2.3.1.24|UniPathway: UPA00870 THL1_RS13890 ad26feabd8c8f219e50df0713e410718 350 PANTHER PTHR37418:SF2 13 141 8.7E-31 T 13-09-2016 THL1_RS13890 ad26feabd8c8f219e50df0713e410718 350 PANTHER PTHR37418:SF2 163 322 8.7E-31 T 13-09-2016 THL1_RS13890 ad26feabd8c8f219e50df0713e410718 350 Gene3D G3DSA:3.20.20.70 13 320 1.7E-82 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS13890 ad26feabd8c8f219e50df0713e410718 350 PANTHER PTHR37418 163 322 8.7E-31 T 13-09-2016 THL1_RS13890 ad26feabd8c8f219e50df0713e410718 350 PANTHER PTHR37418 13 141 8.7E-31 T 13-09-2016 THL1_RS04675 2e7ac888ca0dcf484c0e6087265f5dc6 258 Gene3D G3DSA:2.40.30.10 7 98 3.8E-28 T 13-09-2016 THL1_RS04675 2e7ac888ca0dcf484c0e6087265f5dc6 258 PANTHER PTHR19370 1 242 1.3E-107 T 13-09-2016 THL1_RS04675 2e7ac888ca0dcf484c0e6087265f5dc6 258 Pfam PF00970 Oxidoreductase FAD-binding domain 23 96 2.3E-8 T 13-09-2016 IPR008333 Oxidoreductase, FAD-binding domain THL1_RS04675 2e7ac888ca0dcf484c0e6087265f5dc6 258 SUPERFAMILY SSF52343 109 258 7.2E-35 T 13-09-2016 THL1_RS04675 2e7ac888ca0dcf484c0e6087265f5dc6 258 PANTHER PTHR19370:SF98 1 242 1.3E-107 T 13-09-2016 THL1_RS04675 2e7ac888ca0dcf484c0e6087265f5dc6 258 PRINTS PR00410 Phenol hydroxylase reductase family signature 141 150 1.9E-7 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS04675 2e7ac888ca0dcf484c0e6087265f5dc6 258 PRINTS PR00410 Phenol hydroxylase reductase family signature 116 135 1.9E-7 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS04675 2e7ac888ca0dcf484c0e6087265f5dc6 258 PRINTS PR00410 Phenol hydroxylase reductase family signature 36 48 1.9E-7 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS04675 2e7ac888ca0dcf484c0e6087265f5dc6 258 PRINTS PR00410 Phenol hydroxylase reductase family signature 219 227 1.9E-7 T 13-09-2016 IPR001221 Phenol hydroxylase reductase GO:0055114 THL1_RS04675 2e7ac888ca0dcf484c0e6087265f5dc6 258 SUPERFAMILY SSF63380 7 104 1.72E-22 T 13-09-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 THL1_RS04675 2e7ac888ca0dcf484c0e6087265f5dc6 258 Gene3D G3DSA:3.40.50.80 103 258 1.1E-44 T 13-09-2016 THL1_RS04675 2e7ac888ca0dcf484c0e6087265f5dc6 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 141 150 1.6E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS04675 2e7ac888ca0dcf484c0e6087265f5dc6 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 219 227 1.6E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS04675 2e7ac888ca0dcf484c0e6087265f5dc6 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 116 135 1.6E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS04675 2e7ac888ca0dcf484c0e6087265f5dc6 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 56 63 1.6E-6 T 13-09-2016 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THL1_RS04675 2e7ac888ca0dcf484c0e6087265f5dc6 258 Pfam PF00175 Oxidoreductase NAD-binding domain 117 233 3.1E-12 T 13-09-2016 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THL1_RS01610 1088b3f39c5fc4b068dadbca283bdc32 129 PANTHER PTHR11049 1 126 1.0E-61 T 13-09-2016 THL1_RS01610 1088b3f39c5fc4b068dadbca283bdc32 129 PANTHER PTHR11049:SF13 1 126 1.0E-61 T 13-09-2016 THL1_RS01610 1088b3f39c5fc4b068dadbca283bdc32 129 SUPERFAMILY SSF54637 4 121 6.54E-23 T 13-09-2016 IPR029069 HotDog domain THL1_RS01610 1088b3f39c5fc4b068dadbca283bdc32 129 Pfam PF03061 Thioesterase superfamily 17 92 3.3E-12 T 13-09-2016 IPR006683 Thioesterase domain THL1_RS01610 1088b3f39c5fc4b068dadbca283bdc32 129 Gene3D G3DSA:3.10.129.10 3 117 9.3E-22 T 13-09-2016 IPR029069 HotDog domain THL1_RS08465 a94a1fe9a87405eb1b296954e418bb60 258 Pfam PF12706 Beta-lactamase superfamily domain 18 190 5.2E-9 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS08465 a94a1fe9a87405eb1b296954e418bb60 258 Gene3D G3DSA:3.60.15.10 1 257 9.8E-21 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS08465 a94a1fe9a87405eb1b296954e418bb60 258 SUPERFAMILY SSF56281 1 223 9.57E-14 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS23445 0fb92a6ee5031c89ec831353e2a6e074 300 Gene3D G3DSA:1.25.40.10 172 280 1.4E-13 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS23445 0fb92a6ee5031c89ec831353e2a6e074 300 Pfam PF03412 Peptidase C39 family 24 149 2.7E-5 T 13-09-2016 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 THL1_RS23445 0fb92a6ee5031c89ec831353e2a6e074 300 SUPERFAMILY SSF48452 188 280 9.73E-13 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS07320 01c87650e3a4f72913cf468255b769dc 189 Pfam PF04268 Sarcosine oxidase, gamma subunit family 33 176 8.5E-11 T 13-09-2016 IPR007375 Sarcosine oxidase, gamma subunit KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 THL1_RS07320 01c87650e3a4f72913cf468255b769dc 189 Gene3D G3DSA:3.30.1360.120 98 187 2.9E-5 T 13-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THL1_RS07320 01c87650e3a4f72913cf468255b769dc 189 SUPERFAMILY SSF103025 8 187 5.49E-19 T 13-09-2016 THL1_RS23085 db2bd0f6cdecb3c11a41cc1adff1643e 83 Pfam PF00886 Ribosomal protein S16 8 68 4.5E-25 T 13-09-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS23085 db2bd0f6cdecb3c11a41cc1adff1643e 83 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 78 1.6E-29 T 13-09-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS23085 db2bd0f6cdecb3c11a41cc1adff1643e 83 PANTHER PTHR12919 1 78 1.7E-39 T 13-09-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS23085 db2bd0f6cdecb3c11a41cc1adff1643e 83 SUPERFAMILY SSF54565 1 78 9.68E-29 T 13-09-2016 IPR023803 Ribosomal protein S16 domain THL1_RS23085 db2bd0f6cdecb3c11a41cc1adff1643e 83 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 23.938 T 13-09-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS23085 db2bd0f6cdecb3c11a41cc1adff1643e 83 Gene3D G3DSA:3.30.1320.10 1 78 4.4E-33 T 13-09-2016 IPR023803 Ribosomal protein S16 domain THL1_RS25190 57337581b625be722c00e7731428d5f4 249 PANTHER PTHR10108 34 156 2.1E-19 T 13-09-2016 THL1_RS25190 57337581b625be722c00e7731428d5f4 249 Gene3D G3DSA:3.40.50.150 34 247 2.7E-31 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS25190 57337581b625be722c00e7731428d5f4 249 Pfam PF13489 Methyltransferase domain 30 159 9.2E-15 T 13-09-2016 THL1_RS25190 57337581b625be722c00e7731428d5f4 249 SUPERFAMILY SSF53335 4 247 6.08E-36 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS27375 314e8cf177832e555d26bd307e961efb 131 Pfam PF07233 Protein of unknown function (DUF1425) 39 121 1.2E-21 T 13-09-2016 IPR010824 Protein of unknown function DUF1425 THL1_RS25905 fd491b01d5561acaa9e1c8fc7024605a 346 Pfam PF00691 OmpA family 174 260 3.1E-12 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS25905 fd491b01d5561acaa9e1c8fc7024605a 346 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 15 63 5.3E-18 T 13-09-2016 IPR025713 Motility protein B, N-terminal domain THL1_RS25905 fd491b01d5561acaa9e1c8fc7024605a 346 PANTHER PTHR30329 1 301 8.0E-132 T 13-09-2016 THL1_RS25905 fd491b01d5561acaa9e1c8fc7024605a 346 SUPERFAMILY SSF103088 172 277 2.88E-20 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS25905 fd491b01d5561acaa9e1c8fc7024605a 346 PANTHER PTHR30329:SF2 1 301 8.0E-132 T 13-09-2016 THL1_RS25905 fd491b01d5561acaa9e1c8fc7024605a 346 Gene3D G3DSA:3.30.1330.60 170 277 2.6E-17 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS27260 8b942a04c7d26aabb223bf8a3e4cc735 69 TIGRFAM TIGR02449 TIGR02449: TIGR02449 family protein 5 69 1.0E-28 T 13-09-2016 IPR012662 Conserved hypothetical protein CHP02449 THL1_RS27725 8353b1b551f4d6edd5ee2d781342f79b 161 Pfam PF10387 Protein of unknown function (DUF2442) 10 78 4.5E-9 T 13-09-2016 IPR018841 Protein of unknown function DUF2442 THL1_RS27725 8353b1b551f4d6edd5ee2d781342f79b 161 SUPERFAMILY SSF47413 92 149 3.02E-14 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS27725 8353b1b551f4d6edd5ee2d781342f79b 161 Gene3D G3DSA:3.30.2020.10 4 85 1.5E-18 T 13-09-2016 IPR018841 Protein of unknown function DUF2442 THL1_RS27725 8353b1b551f4d6edd5ee2d781342f79b 161 Gene3D G3DSA:1.10.260.40 91 152 1.7E-20 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS27725 8353b1b551f4d6edd5ee2d781342f79b 161 SUPERFAMILY SSF143880 7 85 1.96E-16 T 13-09-2016 IPR018841 Protein of unknown function DUF2442 THL1_RS03230 a5e3a3391f0bbd5bf79a1ee211a19484 395 TIGRFAM TIGR02360 pbenz_hydroxyl: 4-hydroxybenzoate 3-monooxygenase 1 391 2.0E-204 T 13-09-2016 IPR012733 4-hydroxybenzoate 3-monooxygenase GO:0018659|GO:0043639|GO:0050660|GO:0055114 THL1_RS03230 a5e3a3391f0bbd5bf79a1ee211a19484 395 Pfam PF01494 FAD binding domain 2 342 3.8E-89 T 13-09-2016 IPR002938 FAD-binding domain GO:0071949 THL1_RS03230 a5e3a3391f0bbd5bf79a1ee211a19484 395 Gene3D G3DSA:3.50.50.60 2 74 8.5E-6 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS03230 a5e3a3391f0bbd5bf79a1ee211a19484 395 SUPERFAMILY SSF54373 175 275 1.96E-45 T 13-09-2016 THL1_RS03230 a5e3a3391f0bbd5bf79a1ee211a19484 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 8.9E-32 T 13-09-2016 THL1_RS03230 a5e3a3391f0bbd5bf79a1ee211a19484 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 8.9E-32 T 13-09-2016 THL1_RS03230 a5e3a3391f0bbd5bf79a1ee211a19484 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 310 328 8.9E-32 T 13-09-2016 THL1_RS03230 a5e3a3391f0bbd5bf79a1ee211a19484 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 8.9E-32 T 13-09-2016 THL1_RS03230 a5e3a3391f0bbd5bf79a1ee211a19484 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 8.9E-32 T 13-09-2016 THL1_RS03230 a5e3a3391f0bbd5bf79a1ee211a19484 395 PANTHER PTHR13789:SF192 1 395 1.4E-200 T 13-09-2016 THL1_RS03230 a5e3a3391f0bbd5bf79a1ee211a19484 395 PANTHER PTHR13789 1 395 1.4E-200 T 13-09-2016 THL1_RS03230 a5e3a3391f0bbd5bf79a1ee211a19484 395 Gene3D G3DSA:3.50.50.60 93 146 1.6E-4 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS03230 a5e3a3391f0bbd5bf79a1ee211a19484 395 SUPERFAMILY SSF51905 274 354 3.6E-55 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS03230 a5e3a3391f0bbd5bf79a1ee211a19484 395 SUPERFAMILY SSF51905 1 172 3.6E-55 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS03230 a5e3a3391f0bbd5bf79a1ee211a19484 395 Gene3D G3DSA:3.30.9.10 147 299 2.1E-68 T 13-09-2016 THL1_RS03750 2b4da7478cfee9284b0309eeeaec13b9 1244 PANTHER PTHR23304 26 1244 0.0 T 13-09-2016 THL1_RS03750 2b4da7478cfee9284b0309eeeaec13b9 1244 TIGRFAM TIGR02257 cobalto_cobN: cobaltochelatase, CobN subunit 1 1242 0.0 T 13-09-2016 IPR011953 Cobaltochelatase, CobN subunit GO:0009236|GO:0051116 THL1_RS03750 2b4da7478cfee9284b0309eeeaec13b9 1244 Pfam PF02514 CobN/Magnesium Chelatase 138 1228 0.0 T 13-09-2016 IPR003672 CobN/magnesium chelatase GO:0009058 THL1_RS03750 2b4da7478cfee9284b0309eeeaec13b9 1244 PANTHER PTHR23304:SF96 26 1244 0.0 T 13-09-2016 THL1_RS00860 0239df2448d257c2ea43333ff60b13d7 93 PANTHER PTHR30024:SF4 1 44 2.6E-13 T 13-09-2016 THL1_RS00860 0239df2448d257c2ea43333ff60b13d7 93 PANTHER PTHR30024 1 44 2.6E-13 T 13-09-2016 THL1_RS09025 f73457e50ed14819a7cbcfe0f9743276 444 PANTHER PTHR21343 1 443 1.2E-136 T 13-09-2016 THL1_RS09025 f73457e50ed14819a7cbcfe0f9743276 444 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 20 435 37.673 T 13-09-2016 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 THL1_RS09025 f73457e50ed14819a7cbcfe0f9743276 444 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 24 441 8.2E-81 T 13-09-2016 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 THL1_RS09025 f73457e50ed14819a7cbcfe0f9743276 444 Gene3D G3DSA:3.40.50.880 252 439 4.2E-24 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS09025 f73457e50ed14819a7cbcfe0f9743276 444 SUPERFAMILY SSF52317 251 442 4.89E-32 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS09025 f73457e50ed14819a7cbcfe0f9743276 444 PANTHER PTHR21343:SF6 1 443 1.2E-136 T 13-09-2016 THL1_RS09025 f73457e50ed14819a7cbcfe0f9743276 444 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 253 431 3.4E-29 T 13-09-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 THL1_RS09025 f73457e50ed14819a7cbcfe0f9743276 444 Gene3D G3DSA:3.40.50.300 20 207 1.4E-20 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09025 f73457e50ed14819a7cbcfe0f9743276 444 SUPERFAMILY SSF52540 22 207 4.47E-40 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09025 f73457e50ed14819a7cbcfe0f9743276 444 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 24 176 8.7E-18 T 13-09-2016 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THL1_RS15765 f34e9111525df3e50a115bec98256403 102 Pfam PF04341 Protein of unknown function, DUF485 11 97 3.4E-32 T 13-09-2016 IPR007436 Protein of unknown function DUF485 THL1_RS15765 f34e9111525df3e50a115bec98256403 102 PANTHER PTHR38598 2 102 5.8E-30 T 13-09-2016 THL1_RS23505 fbe4024f7b55a5d5cd803e9acab93622 368 SUPERFAMILY SSF47005 112 153 5.36E-10 T 13-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 THL1_RS23505 fbe4024f7b55a5d5cd803e9acab93622 368 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 163 368 3.7E-50 T 13-09-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 THL1_RS23505 fbe4024f7b55a5d5cd803e9acab93622 368 PANTHER PTHR23151:SF65 1 368 1.2E-206 T 13-09-2016 THL1_RS23505 fbe4024f7b55a5d5cd803e9acab93622 368 SUPERFAMILY SSF51230 2 84 4.58E-25 T 13-09-2016 IPR011053 Single hybrid motif THL1_RS23505 fbe4024f7b55a5d5cd803e9acab93622 368 Gene3D G3DSA:2.40.50.100 4 83 2.2E-24 T 13-09-2016 THL1_RS23505 fbe4024f7b55a5d5cd803e9acab93622 368 Pfam PF02817 e3 binding domain 114 149 8.9E-14 T 13-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 THL1_RS23505 fbe4024f7b55a5d5cd803e9acab93622 368 PANTHER PTHR23151 1 368 1.2E-206 T 13-09-2016 THL1_RS23505 fbe4024f7b55a5d5cd803e9acab93622 368 Gene3D G3DSA:4.10.320.10 113 154 2.9E-15 T 13-09-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 THL1_RS23505 fbe4024f7b55a5d5cd803e9acab93622 368 Gene3D G3DSA:3.30.559.10 155 368 1.4E-52 T 13-09-2016 IPR023213 Chloramphenicol acetyltransferase-like domain THL1_RS23505 fbe4024f7b55a5d5cd803e9acab93622 368 SUPERFAMILY SSF52777 154 368 9.78E-57 T 13-09-2016 THL1_RS23505 fbe4024f7b55a5d5cd803e9acab93622 368 Pfam PF00364 Biotin-requiring enzyme 4 73 3.0E-20 T 13-09-2016 IPR000089 Biotin/lipoyl attachment THL1_RS20705 6f5924aa32d9c100b133813fd7787aa5 68 Pfam PF09722 Protein of unknown function (DUF2384) 16 65 1.5E-11 T 13-09-2016 IPR024467 Domain of unknown function DUF2384 THL1_RS04480 3865d61d0391a3654712212fbcc7ee68 220 Pfam PF06790 Uncharacterised protein family (UPF0259) 62 211 2.2E-10 T 13-09-2016 IPR009627 Uncharacterised protein family UPF0259 THL1_RS04035 6462126d9ee222af35acccfe935af472 168 PANTHER PTHR30265:SF3 9 168 9.9E-27 T 13-09-2016 THL1_RS04035 6462126d9ee222af35acccfe935af472 168 SUPERFAMILY SSF82679 8 107 1.7E-28 T 13-09-2016 IPR006645 NusG, N-terminal GO:0006355 THL1_RS04035 6462126d9ee222af35acccfe935af472 168 Hamap MF_00951 Transcription antitermination protein RfaH [rfaH]. 7 168 42.245 T 13-09-2016 IPR010215 Transcription antitermination protein RfaH GO:0006355 THL1_RS04035 6462126d9ee222af35acccfe935af472 168 Gene3D G3DSA:3.30.70.940 8 106 1.1E-20 T 13-09-2016 IPR006645 NusG, N-terminal GO:0006355 THL1_RS04035 6462126d9ee222af35acccfe935af472 168 SMART SM00738 7 106 3.0E-22 T 13-09-2016 IPR006645 NusG, N-terminal GO:0006355 THL1_RS04035 6462126d9ee222af35acccfe935af472 168 TIGRFAM TIGR01955 RfaH: transcription elongation factor/antiterminator RfaH 10 165 1.8E-52 T 13-09-2016 IPR010215 Transcription antitermination protein RfaH GO:0006355 THL1_RS04035 6462126d9ee222af35acccfe935af472 168 PANTHER PTHR30265 9 168 9.9E-27 T 13-09-2016 THL1_RS04035 6462126d9ee222af35acccfe935af472 168 Pfam PF02357 Transcription termination factor nusG 9 102 5.0E-22 T 13-09-2016 IPR006645 NusG, N-terminal GO:0006355 THL1_RS22420 61fd33c6c350385586b7cfed16956e9d 308 SUPERFAMILY SSF46785 1 105 1.11E-19 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS22420 61fd33c6c350385586b7cfed16956e9d 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.0E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS22420 61fd33c6c350385586b7cfed16956e9d 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.0E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS22420 61fd33c6c350385586b7cfed16956e9d 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.0E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS22420 61fd33c6c350385586b7cfed16956e9d 308 Gene3D G3DSA:3.40.190.10 176 258 8.9E-25 T 13-09-2016 THL1_RS22420 61fd33c6c350385586b7cfed16956e9d 308 Gene3D G3DSA:3.40.190.10 91 175 6.8E-18 T 13-09-2016 THL1_RS22420 61fd33c6c350385586b7cfed16956e9d 308 PANTHER PTHR30126 3 307 4.5E-106 T 13-09-2016 THL1_RS22420 61fd33c6c350385586b7cfed16956e9d 308 SUPERFAMILY SSF53850 91 295 2.02E-50 T 13-09-2016 THL1_RS22420 61fd33c6c350385586b7cfed16956e9d 308 Pfam PF03466 LysR substrate binding domain 91 291 1.3E-56 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS22420 61fd33c6c350385586b7cfed16956e9d 308 PANTHER PTHR30126:SF36 3 307 4.5E-106 T 13-09-2016 THL1_RS22420 61fd33c6c350385586b7cfed16956e9d 308 Gene3D G3DSA:1.10.10.10 3 85 1.5E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS22420 61fd33c6c350385586b7cfed16956e9d 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 2.0E-16 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS28045 019fa420afad744aa279db59c4cec34a 434 Gene3D G3DSA:2.120.10.30 12 16 6.1E-60 T 13-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like THL1_RS28045 019fa420afad744aa279db59c4cec34a 434 Gene3D G3DSA:2.120.10.30 61 431 6.1E-60 T 13-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like THL1_RS28045 019fa420afad744aa279db59c4cec34a 434 PANTHER PTHR19328 127 432 4.9E-162 T 13-09-2016 THL1_RS28045 019fa420afad744aa279db59c4cec34a 434 PANTHER PTHR19328:SF26 127 432 4.9E-162 T 13-09-2016 THL1_RS28045 019fa420afad744aa279db59c4cec34a 434 Pfam PF07995 Glucose / Sorbosone dehydrogenase 198 358 4.0E-15 T 13-09-2016 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 THL1_RS28045 019fa420afad744aa279db59c4cec34a 434 PANTHER PTHR19328 40 97 4.9E-162 T 13-09-2016 THL1_RS28045 019fa420afad744aa279db59c4cec34a 434 SUPERFAMILY SSF50952 123 432 1.22E-37 T 13-09-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 THL1_RS28045 019fa420afad744aa279db59c4cec34a 434 SUPERFAMILY SSF50952 59 94 1.22E-37 T 13-09-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 THL1_RS28045 019fa420afad744aa279db59c4cec34a 434 PANTHER PTHR19328:SF26 40 97 4.9E-162 T 13-09-2016 THL1_RS22240 b8caf025f86f432ad87d63af6c1de18d 234 Gene3D G3DSA:3.40.50.300 3 164 8.3E-44 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22240 b8caf025f86f432ad87d63af6c1de18d 234 Pfam PF00308 Bacterial dnaA protein 13 197 2.0E-17 T 13-09-2016 IPR013317 Chromosomal replication initiator protein DnaA THL1_RS22240 b8caf025f86f432ad87d63af6c1de18d 234 Gene3D G3DSA:1.10.8.60 168 233 9.4E-28 T 13-09-2016 THL1_RS22240 b8caf025f86f432ad87d63af6c1de18d 234 PANTHER PTHR30050 1 231 1.4E-112 T 13-09-2016 THL1_RS22240 b8caf025f86f432ad87d63af6c1de18d 234 SUPERFAMILY SSF52540 13 212 7.72E-26 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22240 b8caf025f86f432ad87d63af6c1de18d 234 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 5 232 2.3E-89 T 13-09-2016 IPR017788 DnaA regulatory inactivator Hda GO:0032297 THL1_RS22240 b8caf025f86f432ad87d63af6c1de18d 234 PANTHER PTHR30050:SF5 1 231 1.4E-112 T 13-09-2016 THL1_RS25705 bc340be0c265b0c23bf756cf87ca05be 496 PANTHER PTHR11699 24 496 1.1E-271 T 13-09-2016 THL1_RS25705 bc340be0c265b0c23bf756cf87ca05be 496 SUPERFAMILY SSF53720 20 483 2.62E-132 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS25705 bc340be0c265b0c23bf756cf87ca05be 496 Pfam PF00171 Aldehyde dehydrogenase family 20 478 1.4E-128 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS25705 bc340be0c265b0c23bf756cf87ca05be 496 Gene3D G3DSA:3.40.605.10 21 266 1.1E-74 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS25705 bc340be0c265b0c23bf756cf87ca05be 496 PANTHER PTHR11699:SF144 24 496 1.1E-271 T 13-09-2016 THL1_RS25705 bc340be0c265b0c23bf756cf87ca05be 496 Gene3D G3DSA:3.40.309.10 267 455 9.6E-51 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS25705 bc340be0c265b0c23bf756cf87ca05be 496 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS06015 b7bda693939d7707ea679f795704f146 264 Pfam PF00795 Carbon-nitrogen hydrolase 11 248 7.5E-33 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS06015 b7bda693939d7707ea679f795704f146 264 SUPERFAMILY SSF56317 8 256 5.49E-67 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS06015 b7bda693939d7707ea679f795704f146 264 Gene3D G3DSA:3.60.110.10 8 257 5.3E-68 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS06015 b7bda693939d7707ea679f795704f146 264 PANTHER PTHR23088:SF28 1 258 6.2E-140 T 13-09-2016 THL1_RS06015 b7bda693939d7707ea679f795704f146 264 PANTHER PTHR23088 1 258 6.2E-140 T 13-09-2016 THL1_RS06420 f03e21a5c1be80a245f49f4799530a7e 246 PANTHER PTHR38480:SF1 19 242 1.6E-73 T 13-09-2016 THL1_RS06420 f03e21a5c1be80a245f49f4799530a7e 246 PANTHER PTHR38480 19 242 1.6E-73 T 13-09-2016 THL1_RS06420 f03e21a5c1be80a245f49f4799530a7e 246 Pfam PF06271 RDD family 38 161 3.4E-18 T 13-09-2016 IPR010432 RDD THL1_RS00140 687fefb5fab5aa94be663336458a9c43 519 Pfam PF13466 STAS domain 448 507 1.5E-9 T 13-09-2016 IPR002645 STAS domain THL1_RS00140 687fefb5fab5aa94be663336458a9c43 519 Pfam PF00916 Sulfate permease family 24 390 4.4E-84 T 13-09-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 THL1_RS00140 687fefb5fab5aa94be663336458a9c43 519 Gene3D G3DSA:3.30.750.24 427 509 1.0E-13 T 13-09-2016 IPR002645 STAS domain THL1_RS00140 687fefb5fab5aa94be663336458a9c43 519 SUPERFAMILY SSF52091 426 509 1.86E-15 T 13-09-2016 IPR002645 STAS domain THL1_RS00140 687fefb5fab5aa94be663336458a9c43 519 PANTHER PTHR11814:SF71 6 511 6.5E-173 T 13-09-2016 THL1_RS00140 687fefb5fab5aa94be663336458a9c43 519 PANTHER PTHR11814 6 511 6.5E-173 T 13-09-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 THL1_RS28215 187becacfe05427cf72f9086e0179aad 218 PANTHER PTHR30614 1 218 2.8E-89 T 13-09-2016 THL1_RS28215 187becacfe05427cf72f9086e0179aad 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 107 8.3E-29 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS28215 187becacfe05427cf72f9086e0179aad 218 Gene3D G3DSA:1.10.3720.10 11 212 1.9E-46 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS28215 187becacfe05427cf72f9086e0179aad 218 SUPERFAMILY SSF161098 11 201 7.06E-44 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS28215 187becacfe05427cf72f9086e0179aad 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 212 1.4E-16 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS24250 993dc1a86f3432105c5b7deb4f770e12 299 PANTHER PTHR30535 19 288 1.2E-83 T 13-09-2016 THL1_RS24250 993dc1a86f3432105c5b7deb4f770e12 299 PANTHER PTHR30535:SF4 19 288 1.2E-83 T 13-09-2016 THL1_RS24250 993dc1a86f3432105c5b7deb4f770e12 299 Pfam PF01497 Periplasmic binding protein 31 263 2.1E-28 T 13-09-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 THL1_RS24250 993dc1a86f3432105c5b7deb4f770e12 299 Gene3D G3DSA:3.40.50.1980 27 146 2.7E-22 T 13-09-2016 THL1_RS24250 993dc1a86f3432105c5b7deb4f770e12 299 Gene3D G3DSA:3.40.50.1980 157 287 1.6E-19 T 13-09-2016 THL1_RS24250 993dc1a86f3432105c5b7deb4f770e12 299 SUPERFAMILY SSF53807 27 286 1.41E-48 T 13-09-2016 THL1_RS28120 8041e72e0d88e765c60e68c4d8ac9aa6 163 PANTHER PTHR23046 1 162 2.2E-87 T 13-09-2016 THL1_RS28120 8041e72e0d88e765c60e68c4d8ac9aa6 163 Gene3D G3DSA:3.40.50.7700 3 159 4.0E-74 T 13-09-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 THL1_RS28120 8041e72e0d88e765c60e68c4d8ac9aa6 163 PIRSF PIRSF001338 1 162 2.8E-65 T 13-09-2016 IPR024694 N5-carboxyaminoimidazole ribonucleotide mutase PurE GO:0006189|GO:0034023 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234|UniPathway: UPA00074 THL1_RS28120 8041e72e0d88e765c60e68c4d8ac9aa6 163 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 31.619 T 13-09-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 THL1_RS28120 8041e72e0d88e765c60e68c4d8ac9aa6 163 PANTHER PTHR23046:SF2 1 162 2.2E-87 T 13-09-2016 THL1_RS28120 8041e72e0d88e765c60e68c4d8ac9aa6 163 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 159 5.0E-66 T 13-09-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 THL1_RS28120 8041e72e0d88e765c60e68c4d8ac9aa6 163 SMART SM01001 3 154 1.4E-101 T 13-09-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 THL1_RS28120 8041e72e0d88e765c60e68c4d8ac9aa6 163 Pfam PF00731 AIR carboxylase 5 151 5.5E-63 T 13-09-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 THL1_RS28120 8041e72e0d88e765c60e68c4d8ac9aa6 163 SUPERFAMILY SSF52255 4 161 1.44E-66 T 13-09-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 THL1_RS26310 aa7a15079fcec6d68f7980ac5ff21e89 207 PANTHER PTHR39555:SF1 9 203 6.6E-60 T 13-09-2016 THL1_RS26310 aa7a15079fcec6d68f7980ac5ff21e89 207 PIRSF PIRSF016482 4 206 1.2E-81 T 13-09-2016 IPR007445 Pilus assembly protein, PilO THL1_RS26310 aa7a15079fcec6d68f7980ac5ff21e89 207 Gene3D G3DSA:1.10.287.540 67 102 2.2E-19 T 13-09-2016 IPR023218 UPF0291 structural domain THL1_RS26310 aa7a15079fcec6d68f7980ac5ff21e89 207 PANTHER PTHR39555 9 203 6.6E-60 T 13-09-2016 THL1_RS26310 aa7a15079fcec6d68f7980ac5ff21e89 207 Gene3D G3DSA:3.30.70.60 103 204 9.1E-39 T 13-09-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 THL1_RS26310 aa7a15079fcec6d68f7980ac5ff21e89 207 Pfam PF04350 Pilus assembly protein, PilO 58 202 2.9E-56 T 13-09-2016 IPR007445 Pilus assembly protein, PilO THL1_RS23825 dafa613cdcd524cddadfcf560d86a0fb 387 Gene3D G3DSA:3.40.1130.10 93 246 1.4E-6 T 13-09-2016 THL1_RS23825 dafa613cdcd524cddadfcf560d86a0fb 387 Pfam PF01553 Acyltransferase 88 172 1.0E-8 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS23825 dafa613cdcd524cddadfcf560d86a0fb 387 SUPERFAMILY SSF69593 88 290 7.72E-8 T 13-09-2016 THL1_RS23825 dafa613cdcd524cddadfcf560d86a0fb 387 PANTHER PTHR30068:SF3 343 383 8.8E-189 T 13-09-2016 THL1_RS23825 dafa613cdcd524cddadfcf560d86a0fb 387 PANTHER PTHR30068 343 383 8.8E-189 T 13-09-2016 THL1_RS23825 dafa613cdcd524cddadfcf560d86a0fb 387 PANTHER PTHR30068 1 326 8.8E-189 T 13-09-2016 THL1_RS23825 dafa613cdcd524cddadfcf560d86a0fb 387 PANTHER PTHR30068:SF3 1 326 8.8E-189 T 13-09-2016 THL1_RS23825 dafa613cdcd524cddadfcf560d86a0fb 387 SMART SM00563 102 238 0.0023 T 13-09-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 THL1_RS13835 e5c70a1e7b48a6d1adaa78697db650cd 147 SUPERFAMILY SSF46955 1 120 7.69E-23 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS13835 e5c70a1e7b48a6d1adaa78697db650cd 147 Pfam PF13411 MerR HTH family regulatory protein 1 67 4.8E-12 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS13835 e5c70a1e7b48a6d1adaa78697db650cd 147 PANTHER PTHR30204 1 133 2.6E-32 T 13-09-2016 THL1_RS13835 e5c70a1e7b48a6d1adaa78697db650cd 147 PANTHER PTHR30204:SF17 1 133 2.6E-32 T 13-09-2016 THL1_RS13835 e5c70a1e7b48a6d1adaa78697db650cd 147 SMART SM00422 1 69 2.9E-8 T 13-09-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THL1_RS13835 e5c70a1e7b48a6d1adaa78697db650cd 147 Gene3D G3DSA:1.10.1660.10 56 124 5.0E-10 T 13-09-2016 THL1_RS13835 e5c70a1e7b48a6d1adaa78697db650cd 147 Gene3D G3DSA:1.10.1660.10 1 55 2.4E-15 T 13-09-2016 THL1_RS12760 d24360706d8ee110cacaf9760b429eda 142 Pfam PF01047 MarR family 32 89 1.5E-15 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS12760 d24360706d8ee110cacaf9760b429eda 142 SUPERFAMILY SSF46785 3 140 1.86E-31 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS12760 d24360706d8ee110cacaf9760b429eda 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 115 135 7.9E-8 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS12760 d24360706d8ee110cacaf9760b429eda 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 66 81 7.9E-8 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS12760 d24360706d8ee110cacaf9760b429eda 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 85 101 7.9E-8 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS12760 d24360706d8ee110cacaf9760b429eda 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 49 65 7.9E-8 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS12760 d24360706d8ee110cacaf9760b429eda 142 PANTHER PTHR33164 1 139 1.1E-22 T 13-09-2016 THL1_RS12760 d24360706d8ee110cacaf9760b429eda 142 SMART SM00347 25 125 1.1E-18 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS12760 d24360706d8ee110cacaf9760b429eda 142 Gene3D G3DSA:1.10.10.10 2 140 1.1E-36 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS07185 53b88aa568355c667623b43a0bca1f70 667 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 554 583 4.6E-57 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS07185 53b88aa568355c667623b43a0bca1f70 667 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 477 504 4.6E-57 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS07185 53b88aa568355c667623b43a0bca1f70 667 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 400 429 4.6E-57 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS07185 53b88aa568355c667623b43a0bca1f70 667 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 506 535 4.6E-57 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS07185 53b88aa568355c667623b43a0bca1f70 667 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 433 625 1.7E-60 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS07185 53b88aa568355c667623b43a0bca1f70 667 SUPERFAMILY SSF58104 346 627 1.29E-72 T 13-09-2016 THL1_RS07185 53b88aa568355c667623b43a0bca1f70 667 PANTHER PTHR32089 167 629 4.1E-169 T 13-09-2016 THL1_RS07185 53b88aa568355c667623b43a0bca1f70 667 Gene3D G3DSA:3.30.450.20 167 257 1.5E-4 T 13-09-2016 THL1_RS07185 53b88aa568355c667623b43a0bca1f70 667 SMART SM00283 379 626 9.8E-89 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS07185 53b88aa568355c667623b43a0bca1f70 667 Gene3D G3DSA:1.10.287.950 394 598 5.2E-62 T 13-09-2016 THL1_RS07185 53b88aa568355c667623b43a0bca1f70 667 PANTHER PTHR32089:SF63 167 629 4.1E-169 T 13-09-2016 THL1_RS10225 3a1881aa6550ae5bb5ad8e8cef09d32c 323 Gene3D G3DSA:3.40.50.1100 98 306 1.9E-35 T 13-09-2016 THL1_RS10225 3a1881aa6550ae5bb5ad8e8cef09d32c 323 PIRSF PIRSF006278 1 313 6.9E-76 T 13-09-2016 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase THL1_RS10225 3a1881aa6550ae5bb5ad8e8cef09d32c 323 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 25 296 1.1E-11 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS10225 3a1881aa6550ae5bb5ad8e8cef09d32c 323 SUPERFAMILY SSF53686 23 305 5.47E-53 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS18220 6f30e634853b3fe5a73bffedc1230562 286 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 2 281 39.064 T 13-09-2016 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|UniPathway: UPA00248 THL1_RS18220 6f30e634853b3fe5a73bffedc1230562 286 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 78 91 - T 13-09-2016 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|UniPathway: UPA00248 THL1_RS18220 6f30e634853b3fe5a73bffedc1230562 286 SUPERFAMILY SSF53335 3 281 2.9E-87 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS18220 6f30e634853b3fe5a73bffedc1230562 286 Gene3D G3DSA:2.30.140.10 4 53 6.3E-18 T 13-09-2016 THL1_RS18220 6f30e634853b3fe5a73bffedc1230562 286 TIGRFAM TIGR00417 speE: spermidine synthase 6 275 4.3E-105 T 13-09-2016 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|UniPathway: UPA00248 THL1_RS18220 6f30e634853b3fe5a73bffedc1230562 286 PANTHER PTHR11558 4 282 2.2E-117 T 13-09-2016 THL1_RS18220 6f30e634853b3fe5a73bffedc1230562 286 Pfam PF01564 Spermine/spermidine synthase 5 236 5.0E-80 T 13-09-2016 THL1_RS18220 6f30e634853b3fe5a73bffedc1230562 286 Gene3D G3DSA:3.40.50.150 54 282 1.9E-80 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS00850 c87c11ab6eb8b4d5d804046a5fdf8201 574 Pfam PF02910 Fumarate reductase flavoprotein C-term 440 538 2.8E-11 T 13-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 THL1_RS00850 c87c11ab6eb8b4d5d804046a5fdf8201 574 Pfam PF00890 FAD binding domain 9 378 1.3E-37 T 13-09-2016 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain THL1_RS00850 c87c11ab6eb8b4d5d804046a5fdf8201 574 SUPERFAMILY SSF46977 425 552 2.22E-37 T 13-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 THL1_RS00850 c87c11ab6eb8b4d5d804046a5fdf8201 574 Gene3D G3DSA:3.50.50.60 4 277 1.3E-67 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS00850 c87c11ab6eb8b4d5d804046a5fdf8201 574 Gene3D G3DSA:3.50.50.60 356 411 1.3E-67 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS00850 c87c11ab6eb8b4d5d804046a5fdf8201 574 Gene3D G3DSA:1.20.58.100 412 523 1.2E-38 T 13-09-2016 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 THL1_RS00850 c87c11ab6eb8b4d5d804046a5fdf8201 574 PANTHER PTHR11632:SF6 1 569 7.1E-228 T 13-09-2016 THL1_RS00850 c87c11ab6eb8b4d5d804046a5fdf8201 574 PANTHER PTHR11632 1 569 7.1E-228 T 13-09-2016 THL1_RS00850 c87c11ab6eb8b4d5d804046a5fdf8201 574 SUPERFAMILY SSF51905 356 407 5.41E-62 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS00850 c87c11ab6eb8b4d5d804046a5fdf8201 574 SUPERFAMILY SSF51905 5 260 5.41E-62 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS00850 c87c11ab6eb8b4d5d804046a5fdf8201 574 PIRSF PIRSF000171 1 562 6.5E-233 T 13-09-2016 IPR030664 Succinate dehydrogenase/fumarate reductase, alpha/adenylylsulphate reductase subunit THL1_RS00850 c87c11ab6eb8b4d5d804046a5fdf8201 574 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 1.0E-10 T 13-09-2016 THL1_RS00850 c87c11ab6eb8b4d5d804046a5fdf8201 574 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 355 377 1.0E-10 T 13-09-2016 THL1_RS00850 c87c11ab6eb8b4d5d804046a5fdf8201 574 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 370 377 1.5E-6 T 13-09-2016 THL1_RS00850 c87c11ab6eb8b4d5d804046a5fdf8201 574 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 1.5E-6 T 13-09-2016 THL1_RS09460 b6f57f7616f4b3e6b83cc1bcca700ee5 269 Gene3D G3DSA:2.40.230.20 22 269 1.5E-80 T 13-09-2016 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 THL1_RS09460 b6f57f7616f4b3e6b83cc1bcca700ee5 269 Pfam PF03502 Nucleoside-specific channel-forming protein, Tsx 55 258 1.0E-7 T 13-09-2016 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 THL1_RS09460 b6f57f7616f4b3e6b83cc1bcca700ee5 269 SUPERFAMILY SSF111364 29 269 9.15E-69 T 13-09-2016 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 THL1_RS05930 cc2a59da73529ea657fe8d7ab5a68a13 404 Pfam PF00266 Aminotransferase class-V 5 368 3.7E-84 T 13-09-2016 IPR000192 Aminotransferase class V domain THL1_RS05930 cc2a59da73529ea657fe8d7ab5a68a13 404 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 197 216 - T 13-09-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site THL1_RS05930 cc2a59da73529ea657fe8d7ab5a68a13 404 Gene3D G3DSA:3.90.1150.10 254 375 1.2E-48 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS05930 cc2a59da73529ea657fe8d7ab5a68a13 404 SUPERFAMILY SSF53383 5 391 1.33E-108 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS05930 cc2a59da73529ea657fe8d7ab5a68a13 404 PANTHER PTHR11601 4 404 7.2E-230 T 13-09-2016 THL1_RS05930 cc2a59da73529ea657fe8d7ab5a68a13 404 PANTHER PTHR11601:SF45 4 404 7.2E-230 T 13-09-2016 THL1_RS05930 cc2a59da73529ea657fe8d7ab5a68a13 404 Gene3D G3DSA:3.40.640.10 17 253 1.0E-93 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS05930 cc2a59da73529ea657fe8d7ab5a68a13 404 PIRSF PIRSF005572 2 384 1.1E-129 T 13-09-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 THL1_RS05930 cc2a59da73529ea657fe8d7ab5a68a13 404 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 1 395 52.546 T 13-09-2016 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|UniPathway: UPA00266 THL1_RS05930 cc2a59da73529ea657fe8d7ab5a68a13 404 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 1 404 2.8E-228 T 13-09-2016 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250|UniPathway: UPA00266 THL1_RS02705 1c56d7f4cd752bb094e703ff6581453e 66 PANTHER PTHR36154 1 65 1.1E-17 T 13-09-2016 THL1_RS02705 1c56d7f4cd752bb094e703ff6581453e 66 SUPERFAMILY SSF46955 3 54 4.39E-7 T 13-09-2016 IPR009061 Putative DNA-binding domain THL1_RS02705 1c56d7f4cd752bb094e703ff6581453e 66 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 1 51 1.3E-24 T 13-09-2016 IPR010260 Prophage CP4-57 regulatory protein (AlpA) THL1_RS22965 ff07d72c061c2b9b11c10694eb0427fa 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 310 2.4E-14 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS22965 ff07d72c061c2b9b11c10694eb0427fa 316 Gene3D G3DSA:1.10.3720.10 27 304 1.7E-38 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS22965 ff07d72c061c2b9b11c10694eb0427fa 316 PANTHER PTHR30193:SF5 5 310 1.7E-93 T 13-09-2016 THL1_RS22965 ff07d72c061c2b9b11c10694eb0427fa 316 SUPERFAMILY SSF161098 33 310 1.87E-40 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS22965 ff07d72c061c2b9b11c10694eb0427fa 316 PANTHER PTHR30193 5 310 1.7E-93 T 13-09-2016 THL1_RS19905 56877ac3c44d17e451cc2574b726c962 124 SUPERFAMILY SSF50022 14 122 4.19E-32 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS19905 56877ac3c44d17e451cc2574b726c962 124 Gene3D G3DSA:2.102.10.10 14 122 1.2E-35 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS19905 56877ac3c44d17e451cc2574b726c962 124 Pfam PF13806 Rieske-like [2Fe-2S] domain 14 120 2.8E-36 T 13-09-2016 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 THL1_RS19905 56877ac3c44d17e451cc2574b726c962 124 PANTHER PTHR40562 7 116 5.7E-25 T 13-09-2016 THL1_RS19905 56877ac3c44d17e451cc2574b726c962 124 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 15 121 2.7E-27 T 13-09-2016 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 THL1_RS04545 1b513b2735d9329cb7dc8cf4fa0d332f 488 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS04545 1b513b2735d9329cb7dc8cf4fa0d332f 488 SUPERFAMILY SSF53720 3 478 2.23E-167 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS04545 1b513b2735d9329cb7dc8cf4fa0d332f 488 Pfam PF00171 Aldehyde dehydrogenase family 11 475 5.4E-171 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS04545 1b513b2735d9329cb7dc8cf4fa0d332f 488 PANTHER PTHR11699:SF187 4 487 4.0E-260 T 13-09-2016 THL1_RS04545 1b513b2735d9329cb7dc8cf4fa0d332f 488 Gene3D G3DSA:3.40.605.10 3 264 2.9E-101 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS04545 1b513b2735d9329cb7dc8cf4fa0d332f 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 250 257 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS04545 1b513b2735d9329cb7dc8cf4fa0d332f 488 PANTHER PTHR11699 4 487 4.0E-260 T 13-09-2016 THL1_RS04545 1b513b2735d9329cb7dc8cf4fa0d332f 488 Gene3D G3DSA:3.40.309.10 265 450 3.4E-68 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 Pfam PF00224 Pyruvate kinase, barrel domain 5 334 8.9E-112 T 13-09-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 PRINTS PR01050 Pyruvate kinase family signature 214 240 1.8E-62 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 PRINTS PR01050 Pyruvate kinase family signature 62 78 1.8E-62 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 PRINTS PR01050 Pyruvate kinase family signature 310 326 1.8E-62 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 PRINTS PR01050 Pyruvate kinase family signature 187 201 1.8E-62 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 PRINTS PR01050 Pyruvate kinase family signature 241 265 1.8E-62 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 PRINTS PR01050 Pyruvate kinase family signature 266 290 1.8E-62 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 PRINTS PR01050 Pyruvate kinase family signature 291 309 1.8E-62 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 PANTHER PTHR11817 6 469 4.3E-195 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 Gene3D G3DSA:3.40.1380.20 324 467 7.0E-42 T 13-09-2016 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 SUPERFAMILY SSF50800 73 168 3.66E-25 T 13-09-2016 IPR011037 Pyruvate kinase-like, insert domain THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 ProSitePatterns PS00110 Pyruvate kinase active site signature. 212 224 - T 13-09-2016 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 5 469 1.1E-150 T 13-09-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 SUPERFAMILY SSF51621 3 78 1.5E-90 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 SUPERFAMILY SSF51621 168 337 1.5E-90 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 Pfam PF02887 Pyruvate kinase, alpha/beta domain 355 467 4.3E-27 T 13-09-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 Gene3D G3DSA:2.40.33.10 76 168 1.6E-28 T 13-09-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 Gene3D G3DSA:3.20.20.60 169 323 2.3E-92 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 Gene3D G3DSA:3.20.20.60 6 75 2.3E-92 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS09405 a65f0fc1a76d25d0d61a0afa3e6a22e8 471 SUPERFAMILY SSF52935 320 470 1.83E-36 T 13-09-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 THL1_RS25480 6a296508a980f85e367eedbdf1e2d487 453 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 6 41 5.0E-16 T 13-09-2016 IPR011723 Zinc finger/thioredoxin putative THL1_RS25480 6a296508a980f85e367eedbdf1e2d487 453 Pfam PF13719 zinc-ribbon domain 6 41 5.2E-10 T 13-09-2016 IPR011723 Zinc finger/thioredoxin putative THL1_RS25480 6a296508a980f85e367eedbdf1e2d487 453 Pfam PF11906 Protein of unknown function (DUF3426) 306 449 5.4E-37 T 13-09-2016 IPR021834 Protein of unknown function DUF3426 THL1_RS03805 8e297f8cdfd62f3e17b855d3c80b1e86 235 Pfam PF00005 ABC transporter 26 179 3.9E-28 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS03805 8e297f8cdfd62f3e17b855d3c80b1e86 235 Gene3D G3DSA:3.40.50.300 3 224 7.1E-55 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03805 8e297f8cdfd62f3e17b855d3c80b1e86 235 PANTHER PTHR24220 7 225 2.1E-81 T 13-09-2016 THL1_RS03805 8e297f8cdfd62f3e17b855d3c80b1e86 235 SUPERFAMILY SSF52540 4 224 3.55E-49 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS03805 8e297f8cdfd62f3e17b855d3c80b1e86 235 SMART SM00382 31 227 5.2E-10 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS03805 8e297f8cdfd62f3e17b855d3c80b1e86 235 PANTHER PTHR24220:SF578 7 225 2.1E-81 T 13-09-2016 THL1_RS02485 9bc5bd7b82a3aa4edb5933d4d4b36825 340 PANTHER PTHR11019:SF52 185 339 1.7E-36 T 13-09-2016 THL1_RS02485 9bc5bd7b82a3aa4edb5933d4d4b36825 340 SMART SM00342 257 339 3.1E-22 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS02485 9bc5bd7b82a3aa4edb5933d4d4b36825 340 Pfam PF12833 Helix-turn-helix domain 264 339 1.6E-19 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS02485 9bc5bd7b82a3aa4edb5933d4d4b36825 340 Gene3D G3DSA:1.10.10.60 291 339 9.2E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS02485 9bc5bd7b82a3aa4edb5933d4d4b36825 340 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 31 213 2.2E-38 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS02485 9bc5bd7b82a3aa4edb5933d4d4b36825 340 SUPERFAMILY SSF46689 292 340 7.62E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS02485 9bc5bd7b82a3aa4edb5933d4d4b36825 340 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 291 335 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS02485 9bc5bd7b82a3aa4edb5933d4d4b36825 340 PANTHER PTHR11019 185 339 1.7E-36 T 13-09-2016 THL1_RS09030 cc0b4853c0d2532af4d4b86d1d6a0a72 216 PANTHER PTHR21712 1 212 1.9E-87 T 13-09-2016 THL1_RS09030 cc0b4853c0d2532af4d4b86d1d6a0a72 216 PANTHER PTHR21712:SF31 1 212 1.9E-87 T 13-09-2016 THL1_RS09030 cc0b4853c0d2532af4d4b86d1d6a0a72 216 Gene3D G3DSA:3.40.109.10 6 214 8.3E-45 T 13-09-2016 IPR000415 Nitroreductase-like GO:0016491 THL1_RS09030 cc0b4853c0d2532af4d4b86d1d6a0a72 216 Pfam PF00881 Nitroreductase family 18 181 1.2E-27 T 13-09-2016 IPR029479 Nitroreductase THL1_RS09030 cc0b4853c0d2532af4d4b86d1d6a0a72 216 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 6 206 2.1E-72 T 13-09-2016 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 THL1_RS09030 cc0b4853c0d2532af4d4b86d1d6a0a72 216 SUPERFAMILY SSF55469 6 214 2.22E-45 T 13-09-2016 IPR000415 Nitroreductase-like GO:0016491 THL1_RS11210 1983c01f0d07bc0293784e6429429453 476 PANTHER PTHR11785 51 451 8.8E-32 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS11210 1983c01f0d07bc0293784e6429429453 476 Pfam PF13520 Amino acid permease 43 444 6.8E-32 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS11210 1983c01f0d07bc0293784e6429429453 476 PIRSF PIRSF006060 12 475 6.1E-44 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS23095 33435e4d9e98bcc88c48d7adc79503ce 266 PANTHER PTHR38034 4 265 8.4E-85 T 13-09-2016 THL1_RS23095 33435e4d9e98bcc88c48d7adc79503ce 266 Pfam PF01578 Cytochrome C assembly protein 40 263 1.5E-37 T 13-09-2016 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 THL1_RS13145 d06dffbd003e38313eb3a13181a48577 301 SUPERFAMILY SSF110296 256 294 1.57E-27 T 13-09-2016 THL1_RS13145 d06dffbd003e38313eb3a13181a48577 301 SUPERFAMILY SSF110296 33 212 1.57E-27 T 13-09-2016 THL1_RS13145 d06dffbd003e38313eb3a13181a48577 301 Gene3D G3DSA:2.130.10.140 69 295 5.9E-27 T 13-09-2016 THL1_RS13145 d06dffbd003e38313eb3a13181a48577 301 Pfam PF02012 BNR/Asp-box repeat 281 291 0.03 T 13-09-2016 IPR002860 BNR repeat THL1_RS12355 35470f7839ec0213403a051e6fc58f16 147 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 13-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THL1_RS12355 35470f7839ec0213403a051e6fc58f16 147 PANTHER PTHR22769 3 139 1.5E-33 T 13-09-2016 THL1_RS12355 35470f7839ec0213403a051e6fc58f16 147 PANTHER PTHR22769:SF14 3 139 1.5E-33 T 13-09-2016 THL1_RS12355 35470f7839ec0213403a051e6fc58f16 147 Gene3D G3DSA:3.90.79.10 2 143 7.6E-33 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS12355 35470f7839ec0213403a051e6fc58f16 147 Pfam PF00293 NUDIX domain 7 123 4.9E-17 T 13-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 THL1_RS12355 35470f7839ec0213403a051e6fc58f16 147 SUPERFAMILY SSF55811 5 144 2.44E-29 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS23010 7b312e7162675f247964a6592e021fd5 137 PANTHER PTHR33990:SF1 1 135 1.7E-49 T 13-09-2016 THL1_RS23010 7b312e7162675f247964a6592e021fd5 137 Gene3D G3DSA:3.10.180.10 7 135 1.8E-45 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS23010 7b312e7162675f247964a6592e021fd5 137 SUPERFAMILY SSF54593 1 134 9.12E-38 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS23010 7b312e7162675f247964a6592e021fd5 137 PANTHER PTHR33990 1 135 1.7E-49 T 13-09-2016 THL1_RS23010 7b312e7162675f247964a6592e021fd5 137 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 2 131 4.3E-12 T 13-09-2016 IPR028973 3-demethylubiquinone-9 3-methyltransferase THL1_RS25125 23135e9fe9ca895d630986eeef834f77 297 Gene3D G3DSA:1.10.510.10 139 218 2.0E-18 T 13-09-2016 THL1_RS25125 23135e9fe9ca895d630986eeef834f77 297 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 164 175 - T 13-09-2016 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 THL1_RS25125 23135e9fe9ca895d630986eeef834f77 297 PANTHER PTHR10593:SF19 6 274 2.2E-138 T 13-09-2016 THL1_RS25125 23135e9fe9ca895d630986eeef834f77 297 Gene3D G3DSA:3.30.200.20 17 125 5.1E-13 T 13-09-2016 THL1_RS25125 23135e9fe9ca895d630986eeef834f77 297 PANTHER PTHR10593 6 274 2.2E-138 T 13-09-2016 THL1_RS25125 23135e9fe9ca895d630986eeef834f77 297 Pfam PF01163 RIO1 family 31 219 3.1E-45 T 13-09-2016 THL1_RS25125 23135e9fe9ca895d630986eeef834f77 297 SUPERFAMILY SSF56112 18 222 1.88E-20 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS25125 23135e9fe9ca895d630986eeef834f77 297 SMART SM00090 2 235 1.7E-20 T 13-09-2016 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 THL1_RS18815 b8b8d401c656876c3dfad9ced9395a99 203 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 4 180 2.8E-85 T 13-09-2016 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO THL1_RS18815 b8b8d401c656876c3dfad9ced9395a99 203 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 5 181 8.8E-89 T 13-09-2016 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO THL1_RS18815 b8b8d401c656876c3dfad9ced9395a99 203 PANTHER PTHR10422:SF23 23 160 1.9E-91 T 13-09-2016 THL1_RS18815 b8b8d401c656876c3dfad9ced9395a99 203 SUPERFAMILY SSF46626 16 193 1.04E-31 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS18815 b8b8d401c656876c3dfad9ced9395a99 203 PANTHER PTHR10422 23 160 1.9E-91 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS18815 b8b8d401c656876c3dfad9ced9395a99 203 Gene3D G3DSA:1.10.760.10 16 196 5.5E-39 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS03005 a055cbb25c065af13d3144f2dff8bd22 387 Gene3D G3DSA:2.40.160.10 246 380 6.5E-4 T 13-09-2016 IPR023614 Porin domain THL1_RS03005 a055cbb25c065af13d3144f2dff8bd22 387 Pfam PF10082 Putative beta-barrel porin 2 37 384 1.7E-37 T 13-09-2016 IPR018759 Putative beta-barrel porin 2 THL1_RS03005 a055cbb25c065af13d3144f2dff8bd22 387 SUPERFAMILY SSF56935 85 363 3.66E-7 T 13-09-2016 THL1_RS08940 8500322257ff69be88aca06e59993eb5 431 PANTHER PTHR11958:SF49 6 417 2.5E-256 T 13-09-2016 THL1_RS08940 8500322257ff69be88aca06e59993eb5 431 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 296 319 - T 13-09-2016 IPR018107 Sodium:dicarboxylate symporter, conserved site Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS08940 8500322257ff69be88aca06e59993eb5 431 SUPERFAMILY SSF118215 10 402 6.93E-120 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS08940 8500322257ff69be88aca06e59993eb5 431 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 1.8E-33 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS08940 8500322257ff69be88aca06e59993eb5 431 PRINTS PR00173 Glutamate-aspartate symporter signature 45 65 1.8E-33 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS08940 8500322257ff69be88aca06e59993eb5 431 PRINTS PR00173 Glutamate-aspartate symporter signature 75 100 1.8E-33 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS08940 8500322257ff69be88aca06e59993eb5 431 PRINTS PR00173 Glutamate-aspartate symporter signature 146 168 1.8E-33 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS08940 8500322257ff69be88aca06e59993eb5 431 PRINTS PR00173 Glutamate-aspartate symporter signature 328 347 1.8E-33 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS08940 8500322257ff69be88aca06e59993eb5 431 PRINTS PR00173 Glutamate-aspartate symporter signature 193 212 1.8E-33 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS08940 8500322257ff69be88aca06e59993eb5 431 PRINTS PR00173 Glutamate-aspartate symporter signature 293 319 1.8E-33 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS08940 8500322257ff69be88aca06e59993eb5 431 Gene3D G3DSA:1.10.3860.10 6 408 1.0E-119 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS08940 8500322257ff69be88aca06e59993eb5 431 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 3 429 37.901 T 13-09-2016 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 THL1_RS08940 8500322257ff69be88aca06e59993eb5 431 PANTHER PTHR11958 6 417 2.5E-256 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS08940 8500322257ff69be88aca06e59993eb5 431 Pfam PF00375 Sodium:dicarboxylate symporter family 10 402 1.2E-113 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS00890 3a02d3514817274ffbd870cbb2fafeb8 277 Gene3D G3DSA:1.10.3720.10 75 271 8.5E-29 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00890 3a02d3514817274ffbd870cbb2fafeb8 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 269 9.8E-24 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00890 3a02d3514817274ffbd870cbb2fafeb8 277 PANTHER PTHR30151 2 275 2.9E-109 T 13-09-2016 THL1_RS00890 3a02d3514817274ffbd870cbb2fafeb8 277 PANTHER PTHR30151:SF0 2 275 2.9E-109 T 13-09-2016 THL1_RS00890 3a02d3514817274ffbd870cbb2fafeb8 277 SUPERFAMILY SSF161098 77 260 8.63E-37 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS04650 0ec9f165e2c5569a129eb68cb84642b4 193 Gene3D G3DSA:3.90.550.10 1 187 7.4E-33 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS04650 0ec9f165e2c5569a129eb68cb84642b4 193 PANTHER PTHR19136 1 187 2.8E-29 T 13-09-2016 THL1_RS04650 0ec9f165e2c5569a129eb68cb84642b4 193 SUPERFAMILY SSF53448 3 187 5.86E-29 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS04650 0ec9f165e2c5569a129eb68cb84642b4 193 PANTHER PTHR19136:SF78 1 187 2.8E-29 T 13-09-2016 THL1_RS04650 0ec9f165e2c5569a129eb68cb84642b4 193 Pfam PF12804 MobA-like NTP transferase domain 6 164 1.1E-36 T 13-09-2016 IPR025877 MobA-like NTP transferase THL1_RS24205 56a46c7153551e449efda1a5afb9cc43 109 SUPERFAMILY SSF158452 7 107 7.98E-35 T 13-09-2016 IPR023376 YqcC-like domain THL1_RS24205 56a46c7153551e449efda1a5afb9cc43 109 Gene3D G3DSA:1.20.1440.40 7 105 9.1E-33 T 13-09-2016 IPR023376 YqcC-like domain THL1_RS24205 56a46c7153551e449efda1a5afb9cc43 109 PIRSF PIRSF006257 3 109 4.0E-37 T 13-09-2016 IPR007384 Protein of unknown function UCP006257 THL1_RS24205 56a46c7153551e449efda1a5afb9cc43 109 Pfam PF04287 tRNA pseudouridine synthase C 8 104 2.4E-32 T 13-09-2016 IPR023376 YqcC-like domain THL1_RS24205 56a46c7153551e449efda1a5afb9cc43 109 PANTHER PTHR39586 3 109 6.6E-35 T 13-09-2016 THL1_RS20375 2a1ceab5133dd76b1831d804da062b2a 403 Pfam PF00589 Phage integrase family 251 392 3.1E-33 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS20375 2a1ceab5133dd76b1831d804da062b2a 403 Gene3D G3DSA:1.10.443.10 197 401 3.2E-46 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS20375 2a1ceab5133dd76b1831d804da062b2a 403 Gene3D G3DSA:1.10.150.130 116 193 5.9E-8 T 13-09-2016 IPR023109 Integrase/recombinase, N-terminal THL1_RS20375 2a1ceab5133dd76b1831d804da062b2a 403 SUPERFAMILY SSF56349 251 400 1.74E-58 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS20375 2a1ceab5133dd76b1831d804da062b2a 403 SUPERFAMILY SSF56349 118 217 1.74E-58 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS20375 2a1ceab5133dd76b1831d804da062b2a 403 Pfam PF13356 Domain of unknown function (DUF4102) 5 82 6.9E-9 T 13-09-2016 IPR025166 Domain of unknown function DUF4102 THL1_RS20375 2a1ceab5133dd76b1831d804da062b2a 403 PANTHER PTHR30349:SF20 243 403 4.7E-52 T 13-09-2016 THL1_RS20375 2a1ceab5133dd76b1831d804da062b2a 403 PANTHER PTHR30349:SF20 122 213 4.7E-52 T 13-09-2016 THL1_RS20375 2a1ceab5133dd76b1831d804da062b2a 403 PANTHER PTHR30349 243 403 4.7E-52 T 13-09-2016 THL1_RS20375 2a1ceab5133dd76b1831d804da062b2a 403 PANTHER PTHR30349 122 213 4.7E-52 T 13-09-2016 THL1_RS08565 19c494fbc8db566154f1cde3b3b8b53c 268 PANTHER PTHR24220 4 246 2.9E-80 T 13-09-2016 THL1_RS08565 19c494fbc8db566154f1cde3b3b8b53c 268 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS08565 19c494fbc8db566154f1cde3b3b8b53c 268 Pfam PF00005 ABC transporter 19 174 8.5E-27 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS08565 19c494fbc8db566154f1cde3b3b8b53c 268 Gene3D G3DSA:3.40.50.300 5 238 6.0E-47 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08565 19c494fbc8db566154f1cde3b3b8b53c 268 PANTHER PTHR24220:SF408 4 246 2.9E-80 T 13-09-2016 THL1_RS08565 19c494fbc8db566154f1cde3b3b8b53c 268 SMART SM00382 28 231 1.7E-12 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS08565 19c494fbc8db566154f1cde3b3b8b53c 268 SUPERFAMILY SSF52540 6 237 7.29E-45 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09470 77ca35844451cd3a717de1d55eedcdec 448 Pfam PF00860 Permease family 21 402 4.2E-102 T 13-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS09470 77ca35844451cd3a717de1d55eedcdec 448 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 17 432 6.2E-116 T 13-09-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 THL1_RS09470 77ca35844451cd3a717de1d55eedcdec 448 PANTHER PTHR11119 15 444 1.9E-114 T 13-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS09470 77ca35844451cd3a717de1d55eedcdec 448 TIGRFAM TIGR03173 pbuX: xanthine permease 26 434 2.9E-157 T 13-09-2016 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 THL1_RS09470 77ca35844451cd3a717de1d55eedcdec 448 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 349 369 - T 13-09-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 THL1_RS20880 23bd0a3220e4998fba3ea7c75a632ff6 106 Gene3D G3DSA:3.10.20.30 1 102 4.2E-34 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS20880 23bd0a3220e4998fba3ea7c75a632ff6 106 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 40 50 - T 13-09-2016 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 THL1_RS20880 23bd0a3220e4998fba3ea7c75a632ff6 106 SUPERFAMILY SSF54292 3 103 3.07E-29 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS20880 23bd0a3220e4998fba3ea7c75a632ff6 106 PANTHER PTHR23426 3 103 5.8E-28 T 13-09-2016 THL1_RS20880 23bd0a3220e4998fba3ea7c75a632ff6 106 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 90 2.8E-12 T 13-09-2016 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THL1_RS20880 23bd0a3220e4998fba3ea7c75a632ff6 106 PRINTS PR00355 Adrenodoxin signature 59 73 4.2E-7 T 13-09-2016 IPR001055 Adrenodoxin GO:0009055|GO:0051537 THL1_RS20880 23bd0a3220e4998fba3ea7c75a632ff6 106 PRINTS PR00355 Adrenodoxin signature 40 50 4.2E-7 T 13-09-2016 IPR001055 Adrenodoxin GO:0009055|GO:0051537 THL1_RS20880 23bd0a3220e4998fba3ea7c75a632ff6 106 PRINTS PR00355 Adrenodoxin signature 82 90 4.2E-7 T 13-09-2016 IPR001055 Adrenodoxin GO:0009055|GO:0051537 THL1_RS04320 2bb90d16e85fb89e49e41d0c65b4deea 339 PANTHER PTHR30473 2 337 2.5E-177 T 13-09-2016 THL1_RS04320 2bb90d16e85fb89e49e41d0c65b4deea 339 Gene3D G3DSA:3.40.50.300 110 313 3.6E-89 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04320 2bb90d16e85fb89e49e41d0c65b4deea 339 PANTHER PTHR30473:SF1 2 337 2.5E-177 T 13-09-2016 THL1_RS04320 2bb90d16e85fb89e49e41d0c65b4deea 339 Pfam PF02562 PhoH-like protein 111 314 4.6E-94 T 13-09-2016 IPR003714 PhoH-like protein GO:0005524 THL1_RS04320 2bb90d16e85fb89e49e41d0c65b4deea 339 SUPERFAMILY SSF52540 110 286 1.05E-39 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18040 7dc66e1276487997c4015ea5b5194217 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 41 53 7.3E-14 T 13-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THL1_RS18040 7dc66e1276487997c4015ea5b5194217 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 15 30 7.3E-14 T 13-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THL1_RS18040 7dc66e1276487997c4015ea5b5194217 164 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 118 133 7.3E-14 T 13-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THL1_RS18040 7dc66e1276487997c4015ea5b5194217 164 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 36 53 - T 13-09-2016 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 THL1_RS18040 7dc66e1276487997c4015ea5b5194217 164 PANTHER PTHR11071:SF192 1 164 7.7E-75 T 13-09-2016 THL1_RS18040 7dc66e1276487997c4015ea5b5194217 164 Gene3D G3DSA:2.40.100.10 2 162 9.2E-52 T 13-09-2016 IPR029000 Cyclophilin-like domain THL1_RS18040 7dc66e1276487997c4015ea5b5194217 164 PIRSF PIRSF001467 1 164 7.8E-28 T 13-09-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 THL1_RS18040 7dc66e1276487997c4015ea5b5194217 164 SUPERFAMILY SSF50891 2 162 5.55E-57 T 13-09-2016 IPR029000 Cyclophilin-like domain THL1_RS18040 7dc66e1276487997c4015ea5b5194217 164 PANTHER PTHR11071 1 164 7.7E-75 T 13-09-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 THL1_RS18040 7dc66e1276487997c4015ea5b5194217 164 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 2 161 1.8E-46 T 13-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THL1_RS19165 1af9ba87fc313e832ef84f6b4a7cf5d0 250 PANTHER PTHR24321 1 244 3.4E-55 T 13-09-2016 THL1_RS19165 1af9ba87fc313e832ef84f6b4a7cf5d0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 6.5E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19165 1af9ba87fc313e832ef84f6b4a7cf5d0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 6.5E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19165 1af9ba87fc313e832ef84f6b4a7cf5d0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 6.5E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19165 1af9ba87fc313e832ef84f6b4a7cf5d0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 6.5E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19165 1af9ba87fc313e832ef84f6b4a7cf5d0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 6.5E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19165 1af9ba87fc313e832ef84f6b4a7cf5d0 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 6.5E-44 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19165 1af9ba87fc313e832ef84f6b4a7cf5d0 250 Gene3D G3DSA:3.40.50.720 2 245 5.9E-84 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS19165 1af9ba87fc313e832ef84f6b4a7cf5d0 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 7.9E-13 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19165 1af9ba87fc313e832ef84f6b4a7cf5d0 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 7.9E-13 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19165 1af9ba87fc313e832ef84f6b4a7cf5d0 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 7.9E-13 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS19165 1af9ba87fc313e832ef84f6b4a7cf5d0 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 242 2.4E-61 T 13-09-2016 THL1_RS19165 1af9ba87fc313e832ef84f6b4a7cf5d0 250 SUPERFAMILY SSF51735 3 244 3.66E-79 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS19165 1af9ba87fc313e832ef84f6b4a7cf5d0 250 PANTHER PTHR24321:SF6 1 244 3.4E-55 T 13-09-2016 THL1_RS19165 1af9ba87fc313e832ef84f6b4a7cf5d0 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 13-09-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THL1_RS23225 55c4b5d38dbe04e5a183c346f3fe2fd8 349 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 328 3.5E-83 T 13-09-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 THL1_RS23225 55c4b5d38dbe04e5a183c346f3fe2fd8 349 PANTHER PTHR22893 1 349 7.1E-170 T 13-09-2016 THL1_RS23225 55c4b5d38dbe04e5a183c346f3fe2fd8 349 SUPERFAMILY SSF51395 1 348 8.8E-121 T 13-09-2016 THL1_RS23225 55c4b5d38dbe04e5a183c346f3fe2fd8 349 PANTHER PTHR22893:SF14 1 349 7.1E-170 T 13-09-2016 THL1_RS23225 55c4b5d38dbe04e5a183c346f3fe2fd8 349 Gene3D G3DSA:3.20.20.70 1 349 1.7E-128 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS19270 268e86981fa74cd1f18130eb7b30f64c 99 Pfam PF03795 YCII-related domain 1 95 3.8E-28 T 13-09-2016 IPR005545 YCII-related THL1_RS19270 268e86981fa74cd1f18130eb7b30f64c 99 Gene3D G3DSA:3.30.70.1060 1 98 3.9E-36 T 13-09-2016 THL1_RS19270 268e86981fa74cd1f18130eb7b30f64c 99 SUPERFAMILY SSF54909 1 98 1.15E-31 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS19270 268e86981fa74cd1f18130eb7b30f64c 99 PANTHER PTHR33606 1 98 1.8E-31 T 13-09-2016 THL1_RS04485 1690aec993049dc490260891a40ed890 241 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 79 227 6.0E-6 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS04485 1690aec993049dc490260891a40ed890 241 PANTHER PTHR35936 42 240 4.9E-19 T 13-09-2016 THL1_RS04485 1690aec993049dc490260891a40ed890 241 SUPERFAMILY SSF53850 43 228 1.19E-17 T 13-09-2016 THL1_RS04485 1690aec993049dc490260891a40ed890 241 PANTHER PTHR35936:SF3 42 240 4.9E-19 T 13-09-2016 THL1_RS11765 a6f3b0128407411232faac776498750d 227 PANTHER PTHR24220 7 227 4.9E-108 T 13-09-2016 THL1_RS11765 a6f3b0128407411232faac776498750d 227 SMART SM00382 34 220 5.4E-16 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS11765 a6f3b0128407411232faac776498750d 227 PANTHER PTHR24220:SF509 7 227 4.9E-108 T 13-09-2016 THL1_RS11765 a6f3b0128407411232faac776498750d 227 Pfam PF00005 ABC transporter 25 171 1.0E-31 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS11765 a6f3b0128407411232faac776498750d 227 SUPERFAMILY SSF52540 5 224 1.61E-67 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11765 a6f3b0128407411232faac776498750d 227 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS11765 a6f3b0128407411232faac776498750d 227 Gene3D G3DSA:3.40.50.300 5 226 2.0E-68 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10135 7e2d402786969101d6b0283a7f9e1a17 655 Pfam PF00263 Bacterial type II and III secretion system protein 435 603 6.0E-53 T 13-09-2016 IPR004846 Type II/III secretion system GO:0009306 THL1_RS10135 7e2d402786969101d6b0283a7f9e1a17 655 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 48 611 4.3E-162 T 13-09-2016 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 THL1_RS10135 7e2d402786969101d6b0283a7f9e1a17 655 PRINTS PR00811 Bacterial general secretion pathway protein D signature 567 585 3.1E-40 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS10135 7e2d402786969101d6b0283a7f9e1a17 655 PRINTS PR00811 Bacterial general secretion pathway protein D signature 590 604 3.1E-40 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS10135 7e2d402786969101d6b0283a7f9e1a17 655 PRINTS PR00811 Bacterial general secretion pathway protein D signature 466 476 3.1E-40 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS10135 7e2d402786969101d6b0283a7f9e1a17 655 PRINTS PR00811 Bacterial general secretion pathway protein D signature 355 365 3.1E-40 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS10135 7e2d402786969101d6b0283a7f9e1a17 655 PRINTS PR00811 Bacterial general secretion pathway protein D signature 431 455 3.1E-40 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS10135 7e2d402786969101d6b0283a7f9e1a17 655 PANTHER PTHR30332:SF3 42 645 2.1E-255 T 13-09-2016 THL1_RS10135 7e2d402786969101d6b0283a7f9e1a17 655 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 548 581 - T 13-09-2016 IPR004845 Type II secretion system GspD, conserved site GO:0008565 THL1_RS10135 7e2d402786969101d6b0283a7f9e1a17 655 PANTHER PTHR30332 42 645 2.1E-255 T 13-09-2016 THL1_RS10135 7e2d402786969101d6b0283a7f9e1a17 655 Pfam PF03958 Bacterial type II/III secretion system short domain 204 268 1.9E-12 T 13-09-2016 IPR005644 NolW-like THL1_RS10135 7e2d402786969101d6b0283a7f9e1a17 655 Pfam PF03958 Bacterial type II/III secretion system short domain 139 198 4.5E-8 T 13-09-2016 IPR005644 NolW-like THL1_RS10135 7e2d402786969101d6b0283a7f9e1a17 655 Pfam PF03958 Bacterial type II/III secretion system short domain 274 355 2.0E-15 T 13-09-2016 IPR005644 NolW-like THL1_RS12560 cbc9653ba5f446a6f91b6c0f7eaeaf30 389 PANTHER PTHR11496:SF75 8 388 3.3E-111 T 13-09-2016 THL1_RS12560 cbc9653ba5f446a6f91b6c0f7eaeaf30 389 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 182 210 - T 13-09-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 THL1_RS12560 cbc9653ba5f446a6f91b6c0f7eaeaf30 389 SUPERFAMILY SSF56796 8 387 1.44E-120 T 13-09-2016 THL1_RS12560 cbc9653ba5f446a6f91b6c0f7eaeaf30 389 Pfam PF00465 Iron-containing alcohol dehydrogenase 13 375 2.1E-110 T 13-09-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 THL1_RS12560 cbc9653ba5f446a6f91b6c0f7eaeaf30 389 Gene3D G3DSA:3.40.50.1970 8 193 9.7E-55 T 13-09-2016 THL1_RS12560 cbc9653ba5f446a6f91b6c0f7eaeaf30 389 PANTHER PTHR11496 8 388 3.3E-111 T 13-09-2016 THL1_RS12560 cbc9653ba5f446a6f91b6c0f7eaeaf30 389 Gene3D G3DSA:1.20.1090.10 194 385 1.0E-54 T 13-09-2016 THL1_RS27335 2eedcfddb2b2ed02387f82124f5f3ffd 337 SMART SM01004 10 333 3.9E-237 T 13-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27335 2eedcfddb2b2ed02387f82124f5f3ffd 337 SUPERFAMILY SSF51569 7 334 6.15E-141 T 13-09-2016 THL1_RS27335 2eedcfddb2b2ed02387f82124f5f3ffd 337 PIRSF PIRSF001415 3 336 1.4E-148 T 13-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27335 2eedcfddb2b2ed02387f82124f5f3ffd 337 Pfam PF00490 Delta-aminolevulinic acid dehydratase 13 331 5.4E-137 T 13-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27335 2eedcfddb2b2ed02387f82124f5f3ffd 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 307 326 1.6E-56 T 13-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27335 2eedcfddb2b2ed02387f82124f5f3ffd 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 161 180 1.6E-56 T 13-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27335 2eedcfddb2b2ed02387f82124f5f3ffd 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 278 293 1.6E-56 T 13-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27335 2eedcfddb2b2ed02387f82124f5f3ffd 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 130 144 1.6E-56 T 13-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27335 2eedcfddb2b2ed02387f82124f5f3ffd 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 199 218 1.6E-56 T 13-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27335 2eedcfddb2b2ed02387f82124f5f3ffd 337 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 253 269 1.6E-56 T 13-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27335 2eedcfddb2b2ed02387f82124f5f3ffd 337 Gene3D G3DSA:3.20.20.70 8 335 5.1E-149 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS27335 2eedcfddb2b2ed02387f82124f5f3ffd 337 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 253 265 - T 13-09-2016 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS27335 2eedcfddb2b2ed02387f82124f5f3ffd 337 PANTHER PTHR11458 8 334 7.7E-183 T 13-09-2016 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|UniPathway: UPA00251 THL1_RS00210 a2e74aea5f7db32b5d90cff44e95097a 77 ProDom PD336997 PRECURSOR SIGNAL MEMBRANE OUTER YNFD ESCHERICHIA EXPORTED PP0087 COLI PP0090 1 74 8.0E-26 T 13-09-2016 IPR010595 Protein of unknown function DUF1161 THL1_RS00210 a2e74aea5f7db32b5d90cff44e95097a 77 Pfam PF06649 Protein of unknown function (DUF1161) 24 74 1.0E-25 T 13-09-2016 IPR010595 Protein of unknown function DUF1161 THL1_RS06480 37a5b03f561a74b0171fb981752066da 376 SUPERFAMILY SSF55785 173 266 1.54E-5 T 13-09-2016 IPR000014 PAS domain THL1_RS06480 37a5b03f561a74b0171fb981752066da 376 SMART SM00091 179 245 8.5E-4 T 13-09-2016 IPR000014 PAS domain THL1_RS06480 37a5b03f561a74b0171fb981752066da 376 SMART SM00421 311 368 2.0E-9 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS06480 37a5b03f561a74b0171fb981752066da 376 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 314 328 7.4E-5 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS06480 37a5b03f561a74b0171fb981752066da 376 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 328 344 7.4E-5 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS06480 37a5b03f561a74b0171fb981752066da 376 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 344 356 7.4E-5 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS06480 37a5b03f561a74b0171fb981752066da 376 Gene3D G3DSA:1.10.10.10 306 370 1.6E-14 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS06480 37a5b03f561a74b0171fb981752066da 376 Gene3D G3DSA:3.30.450.20 173 277 2.0E-7 T 13-09-2016 THL1_RS06480 37a5b03f561a74b0171fb981752066da 376 Pfam PF00196 Bacterial regulatory proteins, luxR family 314 367 6.6E-7 T 13-09-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THL1_RS06480 37a5b03f561a74b0171fb981752066da 376 SUPERFAMILY SSF46894 302 370 6.12E-13 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS15100 28c28a3a818a97f6ec66e943a4c76e77 94 Pfam PF05707 Zonular occludens toxin (Zot) 2 45 1.4E-8 T 13-09-2016 IPR008900 Zona occludens toxin THL1_RS15100 28c28a3a818a97f6ec66e943a4c76e77 94 Gene3D G3DSA:3.40.50.300 1 49 7.2E-6 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25585 6d7bebea27a57b2f054d12d7672d26f5 81 PANTHER PTHR33713:SF5 1 71 3.2E-26 T 13-09-2016 THL1_RS25585 6d7bebea27a57b2f054d12d7672d26f5 81 Gene3D G3DSA:3.40.1620.10 10 53 9.1E-5 T 13-09-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THL1_RS25585 6d7bebea27a57b2f054d12d7672d26f5 81 SUPERFAMILY SSF143120 10 65 1.57E-8 T 13-09-2016 THL1_RS25585 6d7bebea27a57b2f054d12d7672d26f5 81 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 9 72 6.2E-9 T 13-09-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THL1_RS25585 6d7bebea27a57b2f054d12d7672d26f5 81 PANTHER PTHR33713 1 71 3.2E-26 T 13-09-2016 THL1_RS02105 42d7379c745f736640c6779582ddef94 207 Gene3D G3DSA:1.20.1050.10 97 204 3.9E-14 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS02105 42d7379c745f736640c6779582ddef94 207 PANTHER PTHR11260:SF256 4 205 4.7E-62 T 13-09-2016 THL1_RS02105 42d7379c745f736640c6779582ddef94 207 Gene3D G3DSA:3.40.30.10 3 96 8.7E-20 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS02105 42d7379c745f736640c6779582ddef94 207 Pfam PF13410 Glutathione S-transferase, C-terminal domain 137 191 3.4E-7 T 13-09-2016 THL1_RS02105 42d7379c745f736640c6779582ddef94 207 PANTHER PTHR11260 4 205 4.7E-62 T 13-09-2016 THL1_RS02105 42d7379c745f736640c6779582ddef94 207 Pfam PF13417 Glutathione S-transferase, N-terminal domain 7 86 3.7E-17 T 13-09-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THL1_RS02105 42d7379c745f736640c6779582ddef94 207 SUPERFAMILY SSF47616 77 205 2.13E-20 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS02105 42d7379c745f736640c6779582ddef94 207 SUPERFAMILY SSF52833 5 95 6.28E-16 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS02050 1a5dfcba60194ef3edfc404f61f59829 228 Pfam PF10014 2OG-Fe dioxygenase 23 204 1.0E-41 T 13-09-2016 IPR018724 2OG-Fe dioxygenase THL1_RS20610 730a42f2d546b4299280a61c7b874c0e 361 SUPERFAMILY SSF51735 150 321 2.51E-35 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20610 730a42f2d546b4299280a61c7b874c0e 361 SUPERFAMILY SSF50129 3 152 6.54E-37 T 13-09-2016 IPR011032 GroES-like THL1_RS20610 730a42f2d546b4299280a61c7b874c0e 361 SUPERFAMILY SSF50129 330 357 6.54E-37 T 13-09-2016 IPR011032 GroES-like THL1_RS20610 730a42f2d546b4299280a61c7b874c0e 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 13-09-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 THL1_RS20610 730a42f2d546b4299280a61c7b874c0e 361 Gene3D G3DSA:3.40.50.720 182 302 6.3E-32 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS20610 730a42f2d546b4299280a61c7b874c0e 361 SMART SM00829 13 357 0.0035 T 13-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THL1_RS20610 730a42f2d546b4299280a61c7b874c0e 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 138 3.2E-22 T 13-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THL1_RS20610 730a42f2d546b4299280a61c7b874c0e 361 Pfam PF00107 Zinc-binding dehydrogenase 186 319 1.8E-21 T 13-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THL1_RS20610 730a42f2d546b4299280a61c7b874c0e 361 Gene3D G3DSA:3.90.180.10 2 181 1.5E-42 T 13-09-2016 IPR011032 GroES-like THL1_RS20610 730a42f2d546b4299280a61c7b874c0e 361 PANTHER PTHR11695 15 359 1.0E-68 T 13-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 THL1_RS21395 7ef27cc90c001c16aa1102480d14f554 340 Pfam PF05145 Putative ammonia monooxygenase 27 333 1.1E-84 T 13-09-2016 IPR007820 AbrB family GO:0010468|GO:0016021 THL1_RS21395 7ef27cc90c001c16aa1102480d14f554 340 PIRSF PIRSF038991 1 340 6.3E-71 T 13-09-2016 IPR007820 AbrB family GO:0010468|GO:0016021 THL1_RS21395 7ef27cc90c001c16aa1102480d14f554 340 PANTHER PTHR38457 1 335 1.5E-74 T 13-09-2016 THL1_RS21395 7ef27cc90c001c16aa1102480d14f554 340 PANTHER PTHR38457:SF1 1 335 1.5E-74 T 13-09-2016 THL1_RS21395 7ef27cc90c001c16aa1102480d14f554 340 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 4 159 6.7E-36 T 13-09-2016 IPR017516 AbrB duplication THL1_RS21395 7ef27cc90c001c16aa1102480d14f554 340 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 177 332 1.2E-38 T 13-09-2016 IPR017516 AbrB duplication THL1_RS00185 eeda815874c79879574f9588145eab48 74 Pfam PF06649 Protein of unknown function (DUF1161) 24 73 7.0E-23 T 13-09-2016 IPR010595 Protein of unknown function DUF1161 THL1_RS00185 eeda815874c79879574f9588145eab48 74 ProDom PD336997 PRECURSOR SIGNAL MEMBRANE OUTER YNFD ESCHERICHIA EXPORTED PP0087 COLI PP0090 22 74 1.0E-18 T 13-09-2016 IPR010595 Protein of unknown function DUF1161 THL1_RS14235 733ccab6911c50d6f8e978609c12e432 311 PANTHER PTHR11935 7 248 2.8E-27 T 13-09-2016 THL1_RS14235 733ccab6911c50d6f8e978609c12e432 311 SMART SM00849 50 231 2.1E-24 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS14235 733ccab6911c50d6f8e978609c12e432 311 PANTHER PTHR11935:SF95 7 248 2.8E-27 T 13-09-2016 THL1_RS14235 733ccab6911c50d6f8e978609c12e432 311 SUPERFAMILY SSF56281 7 308 6.58E-62 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS14235 733ccab6911c50d6f8e978609c12e432 311 TIGRFAM TIGR04558 SoxH_rel_PQQ_1: quinoprotein relay system zinc metallohydrolase 1 19 303 1.2E-129 T 13-09-2016 IPR030811 Quinoprotein relay system zinc metallohydrolase 1 THL1_RS14235 733ccab6911c50d6f8e978609c12e432 311 Pfam PF00753 Metallo-beta-lactamase superfamily 47 231 1.1E-20 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS14235 733ccab6911c50d6f8e978609c12e432 311 Gene3D G3DSA:3.60.15.10 22 251 9.1E-46 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS05595 b3fe7c3b450d6b7df71ae6453c831a73 151 Pfam PF02381 MraZ protein, putative antitoxin-like 78 131 2.3E-15 T 13-09-2016 IPR020603 MraZ domain THL1_RS05595 b3fe7c3b450d6b7df71ae6453c831a73 151 Pfam PF02381 MraZ protein, putative antitoxin-like 1 75 1.1E-16 T 13-09-2016 IPR020603 MraZ domain THL1_RS05595 b3fe7c3b450d6b7df71ae6453c831a73 151 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 151 54.396 T 13-09-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 THL1_RS05595 b3fe7c3b450d6b7df71ae6453c831a73 151 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 133 2.6E-44 T 13-09-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 THL1_RS05595 b3fe7c3b450d6b7df71ae6453c831a73 151 PANTHER PTHR34701 2 151 4.9E-58 T 13-09-2016 THL1_RS05595 b3fe7c3b450d6b7df71ae6453c831a73 151 SUPERFAMILY SSF89447 2 133 4.92E-43 T 13-09-2016 THL1_RS05595 b3fe7c3b450d6b7df71ae6453c831a73 151 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 132 2.0E-59 T 13-09-2016 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 THL1_RS12095 ac4ee6740e2b206252cf54faf896e26e 313 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 259 293 4.6E-6 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS12095 ac4ee6740e2b206252cf54faf896e26e 313 PANTHER PTHR23416 66 306 2.0E-90 T 13-09-2016 THL1_RS12095 ac4ee6740e2b206252cf54faf896e26e 313 PANTHER PTHR23416:SF65 66 306 2.0E-90 T 13-09-2016 THL1_RS12095 ac4ee6740e2b206252cf54faf896e26e 313 Gene3D G3DSA:2.160.10.10 200 301 2.6E-24 T 13-09-2016 THL1_RS12095 ac4ee6740e2b206252cf54faf896e26e 313 SUPERFAMILY SSF51161 112 300 5.41E-45 T 13-09-2016 IPR011004 Trimeric LpxA-like THL1_RS12095 ac4ee6740e2b206252cf54faf896e26e 313 Gene3D G3DSA:1.10.3130.10 46 199 2.8E-42 T 13-09-2016 THL1_RS25750 331d57a59f83a06a8a1c93c493ec3645 832 SUPERFAMILY SSF56059 24 219 5.3E-24 T 13-09-2016 THL1_RS25750 331d57a59f83a06a8a1c93c493ec3645 832 SUPERFAMILY SSF56059 326 447 5.3E-24 T 13-09-2016 THL1_RS25750 331d57a59f83a06a8a1c93c493ec3645 832 PANTHER PTHR34595 1 832 0.0 T 13-09-2016 THL1_RS25750 331d57a59f83a06a8a1c93c493ec3645 832 PANTHER PTHR34595:SF1 1 832 0.0 T 13-09-2016 THL1_RS25750 331d57a59f83a06a8a1c93c493ec3645 832 Pfam PF14403 Circularly permuted ATP-grasp type 2 81 462 5.5E-154 T 13-09-2016 IPR025841 Circularly permuted ATP-grasp type 2 THL1_RS25750 331d57a59f83a06a8a1c93c493ec3645 832 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 511 819 3.6E-72 T 13-09-2016 IPR007296 Domain of unknown function DUF403 THL1_RS08535 920e8646e679e7ce38a6f7e6b234ffeb 307 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 291 1.2E-57 T 13-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 THL1_RS08535 920e8646e679e7ce38a6f7e6b234ffeb 307 PANTHER PTHR11795 3 307 9.2E-142 T 13-09-2016 THL1_RS08535 920e8646e679e7ce38a6f7e6b234ffeb 307 PANTHER PTHR11795:SF371 3 307 9.2E-142 T 13-09-2016 THL1_RS24910 3c28d032ec12f5a75d560f1c021ed664 60 SUPERFAMILY SSF54786 2 60 2.82E-17 T 13-09-2016 THL1_RS24910 3c28d032ec12f5a75d560f1c021ed664 60 Gene3D G3DSA:3.30.920.30 1 60 3.7E-23 T 13-09-2016 THL1_RS24910 3c28d032ec12f5a75d560f1c021ed664 60 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 4 59 4.0E-21 T 13-09-2016 IPR012933 HicA mRNA interferase family GO:0003729 THL1_RS09290 61c6a4d347dd9b44409837e6aee939b5 247 Gene3D G3DSA:1.10.3720.10 16 221 2.5E-44 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS09290 61c6a4d347dd9b44409837e6aee939b5 247 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 221 2.8E-19 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS09290 61c6a4d347dd9b44409837e6aee939b5 247 PANTHER PTHR30614 1 227 3.3E-68 T 13-09-2016 THL1_RS09290 61c6a4d347dd9b44409837e6aee939b5 247 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 116 3.6E-16 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS09290 61c6a4d347dd9b44409837e6aee939b5 247 SUPERFAMILY SSF161098 17 207 8.9E-39 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01415 7206e5a6bddb70b5f343d4a217c56f54 347 Pfam PF13416 Bacterial extracellular solute-binding protein 40 313 6.9E-28 T 13-09-2016 THL1_RS01415 7206e5a6bddb70b5f343d4a217c56f54 347 Gene3D G3DSA:3.40.190.10 270 314 3.0E-55 T 13-09-2016 THL1_RS01415 7206e5a6bddb70b5f343d4a217c56f54 347 Gene3D G3DSA:3.40.190.10 23 129 3.0E-55 T 13-09-2016 THL1_RS01415 7206e5a6bddb70b5f343d4a217c56f54 347 PIRSF PIRSF019574 4 347 6.6E-114 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS01415 7206e5a6bddb70b5f343d4a217c56f54 347 SUPERFAMILY SSF53850 25 346 1.63E-80 T 13-09-2016 THL1_RS01415 7206e5a6bddb70b5f343d4a217c56f54 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 73 87 3.7E-43 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS01415 7206e5a6bddb70b5f343d4a217c56f54 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 30 46 3.7E-43 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS01415 7206e5a6bddb70b5f343d4a217c56f54 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 89 102 3.7E-43 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS01415 7206e5a6bddb70b5f343d4a217c56f54 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 204 223 3.7E-43 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS01415 7206e5a6bddb70b5f343d4a217c56f54 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 248 267 3.7E-43 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS01415 7206e5a6bddb70b5f343d4a217c56f54 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 293 319 3.7E-43 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS01415 7206e5a6bddb70b5f343d4a217c56f54 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 120 136 3.7E-43 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS01415 7206e5a6bddb70b5f343d4a217c56f54 347 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 46 67 3.7E-43 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS01415 7206e5a6bddb70b5f343d4a217c56f54 347 PANTHER PTHR30222:SF9 10 347 3.8E-196 T 13-09-2016 THL1_RS01415 7206e5a6bddb70b5f343d4a217c56f54 347 Gene3D G3DSA:3.40.190.10 132 269 5.4E-14 T 13-09-2016 THL1_RS01415 7206e5a6bddb70b5f343d4a217c56f54 347 PANTHER PTHR30222 10 347 3.8E-196 T 13-09-2016 THL1_RS12820 8107d6d3c35aac66fa16e982fa9e3d3b 66 Pfam PF00403 Heavy-metal-associated domain 4 60 1.4E-7 T 13-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THL1_RS12820 8107d6d3c35aac66fa16e982fa9e3d3b 66 SUPERFAMILY SSF55008 2 63 2.36E-14 T 13-09-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THL1_RS12820 8107d6d3c35aac66fa16e982fa9e3d3b 66 Gene3D G3DSA:3.30.70.100 2 61 5.1E-16 T 13-09-2016 THL1_RS09735 01b58a3b55b1c37821325e7ed75703db 484 Gene3D G3DSA:1.10.10.60 434 482 4.4E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS09735 01b58a3b55b1c37821325e7ed75703db 484 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 252 267 - T 13-09-2016 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THL1_RS09735 01b58a3b55b1c37821325e7ed75703db 484 SUPERFAMILY SSF55785 34 116 1.43E-7 T 13-09-2016 IPR000014 PAS domain THL1_RS09735 01b58a3b55b1c37821325e7ed75703db 484 SMART SM00382 185 329 7.5E-11 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS09735 01b58a3b55b1c37821325e7ed75703db 484 Pfam PF00158 Sigma-54 interaction domain 176 332 3.1E-56 T 13-09-2016 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THL1_RS09735 01b58a3b55b1c37821325e7ed75703db 484 Pfam PF02954 Bacterial regulatory protein, Fis family 447 483 3.1E-7 T 13-09-2016 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THL1_RS09735 01b58a3b55b1c37821325e7ed75703db 484 Gene3D G3DSA:1.10.8.60 342 410 8.7E-17 T 13-09-2016 THL1_RS09735 01b58a3b55b1c37821325e7ed75703db 484 SUPERFAMILY SSF46689 433 483 1.15E-8 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS09735 01b58a3b55b1c37821325e7ed75703db 484 Gene3D G3DSA:3.30.450.20 34 135 2.8E-10 T 13-09-2016 THL1_RS09735 01b58a3b55b1c37821325e7ed75703db 484 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 378 387 - T 13-09-2016 IPR025944 Sigma-54 interaction domain, conserved site THL1_RS09735 01b58a3b55b1c37821325e7ed75703db 484 Gene3D G3DSA:3.40.50.300 169 338 2.8E-45 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09735 01b58a3b55b1c37821325e7ed75703db 484 SUPERFAMILY SSF52540 174 400 1.11E-60 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09735 01b58a3b55b1c37821325e7ed75703db 484 PANTHER PTHR32071 169 483 2.8E-107 T 13-09-2016 THL1_RS27860 b3ce6037246aae9baf8b5d24ca9559be 259 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 251 2.4E-54 T 13-09-2016 THL1_RS27860 b3ce6037246aae9baf8b5d24ca9559be 259 SUPERFAMILY SSF56219 1 254 1.44E-54 T 13-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase THL1_RS27860 b3ce6037246aae9baf8b5d24ca9559be 259 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 237 8.5E-11 T 13-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase THL1_RS27860 b3ce6037246aae9baf8b5d24ca9559be 259 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 253 4.7E-58 T 13-09-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 THL1_RS27860 b3ce6037246aae9baf8b5d24ca9559be 259 PANTHER PTHR22748 1 255 9.9E-70 T 13-09-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 THL1_RS27860 b3ce6037246aae9baf8b5d24ca9559be 259 Gene3D G3DSA:3.60.10.10 1 254 1.1E-64 T 13-09-2016 IPR005135 Endonuclease/exonuclease/phosphatase THL1_RS09575 330d6ac80feca5569140e83bde60aab1 502 PANTHER PTHR30332:SF1 185 481 1.1E-63 T 13-09-2016 THL1_RS09575 330d6ac80feca5569140e83bde60aab1 502 Pfam PF00263 Bacterial type II and III secretion system protein 278 447 3.6E-43 T 13-09-2016 IPR004846 Type II/III secretion system GO:0009306 THL1_RS09575 330d6ac80feca5569140e83bde60aab1 502 Pfam PF13629 Pilus formation protein N terminal region 42 110 8.4E-20 T 13-09-2016 IPR032789 Pilus formation protein, N-terminal THL1_RS09575 330d6ac80feca5569140e83bde60aab1 502 PANTHER PTHR30332 185 481 1.1E-63 T 13-09-2016 THL1_RS09575 330d6ac80feca5569140e83bde60aab1 502 PRINTS PR00811 Bacterial general secretion pathway protein D signature 436 450 1.7E-14 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS09575 330d6ac80feca5569140e83bde60aab1 502 PRINTS PR00811 Bacterial general secretion pathway protein D signature 274 298 1.7E-14 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS09575 330d6ac80feca5569140e83bde60aab1 502 PRINTS PR00811 Bacterial general secretion pathway protein D signature 413 431 1.7E-14 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS09575 330d6ac80feca5569140e83bde60aab1 502 PRINTS PR00811 Bacterial general secretion pathway protein D signature 197 207 1.7E-14 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS02845 43dd00416db3bfef5fda64f9b59564d0 192 SUPERFAMILY SSF55073 76 186 7.85E-33 T 13-09-2016 IPR029787 Nucleotide cyclase THL1_RS02845 43dd00416db3bfef5fda64f9b59564d0 192 Pfam PF00990 Diguanylate cyclase, GGDEF domain 71 185 8.8E-34 T 13-09-2016 IPR000160 GGDEF domain THL1_RS02845 43dd00416db3bfef5fda64f9b59564d0 192 PANTHER PTHR10799 105 178 8.5E-19 T 13-09-2016 THL1_RS02845 43dd00416db3bfef5fda64f9b59564d0 192 PANTHER PTHR10799:SF750 105 178 8.5E-19 T 13-09-2016 THL1_RS02845 43dd00416db3bfef5fda64f9b59564d0 192 SMART SM00267 60 191 1.6E-24 T 13-09-2016 IPR000160 GGDEF domain THL1_RS02845 43dd00416db3bfef5fda64f9b59564d0 192 SUPERFAMILY SSF55785 3 68 1.19E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS02845 43dd00416db3bfef5fda64f9b59564d0 192 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 67 187 3.4E-38 T 13-09-2016 IPR000160 GGDEF domain THL1_RS02845 43dd00416db3bfef5fda64f9b59564d0 192 Gene3D G3DSA:3.30.70.270 82 186 5.2E-36 T 13-09-2016 THL1_RS02845 43dd00416db3bfef5fda64f9b59564d0 192 Gene3D G3DSA:3.30.450.20 4 81 3.1E-10 T 13-09-2016 THL1_RS06990 8f28bec8c7abbf89b7a289da57491552 298 SUPERFAMILY SSF53335 107 258 7.64E-12 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS06990 8f28bec8c7abbf89b7a289da57491552 298 Gene3D G3DSA:3.40.50.150 161 267 5.4E-9 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS13030 7b4f09fefa994054941900453f0c688f 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 50 8.2E-17 T 13-09-2016 THL1_RS13030 7b4f09fefa994054941900453f0c688f 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 8.0E-10 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS13030 7b4f09fefa994054941900453f0c688f 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 8.0E-10 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS13030 7b4f09fefa994054941900453f0c688f 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 8.0E-10 T 13-09-2016 IPR000485 AsnC-type HTH domain GO:0006355|GO:0043565 THL1_RS13030 7b4f09fefa994054941900453f0c688f 158 Pfam PF01037 Lrp/AsnC ligand binding domain 70 143 2.2E-16 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS13030 7b4f09fefa994054941900453f0c688f 158 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 13-09-2016 IPR019885 Transcription regulator HTH, AsnC-type, conserved site THL1_RS13030 7b4f09fefa994054941900453f0c688f 158 SMART SM00344 3 112 3.9E-37 T 13-09-2016 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 THL1_RS13030 7b4f09fefa994054941900453f0c688f 158 SUPERFAMILY SSF46785 2 63 6.25E-14 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13030 7b4f09fefa994054941900453f0c688f 158 PANTHER PTHR30154 1 153 4.1E-47 T 13-09-2016 THL1_RS13030 7b4f09fefa994054941900453f0c688f 158 SUPERFAMILY SSF54909 65 151 2.82E-15 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS13030 7b4f09fefa994054941900453f0c688f 158 Gene3D G3DSA:1.10.10.10 1 54 1.5E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13030 7b4f09fefa994054941900453f0c688f 158 PANTHER PTHR30154:SF28 1 153 4.1E-47 T 13-09-2016 THL1_RS13030 7b4f09fefa994054941900453f0c688f 158 Gene3D G3DSA:3.30.70.920 55 152 2.1E-22 T 13-09-2016 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THL1_RS09855 47081bfcd19e3fb0df87a63b762ac244 205 Gene3D G3DSA:3.40.50.20 2 87 8.1E-23 T 13-09-2016 IPR016185 Pre-ATP-grasp domain THL1_RS09855 47081bfcd19e3fb0df87a63b762ac244 205 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 4 203 4.9E-68 T 13-09-2016 IPR020019 Sialic acid O-acyltransferase NeuD-like THL1_RS09855 47081bfcd19e3fb0df87a63b762ac244 205 PANTHER PTHR23416:SF23 67 204 8.6E-28 T 13-09-2016 THL1_RS09855 47081bfcd19e3fb0df87a63b762ac244 205 Gene3D G3DSA:2.160.10.10 90 204 3.1E-28 T 13-09-2016 THL1_RS09855 47081bfcd19e3fb0df87a63b762ac244 205 SUPERFAMILY SSF51161 3 204 2.22E-45 T 13-09-2016 IPR011004 Trimeric LpxA-like THL1_RS09855 47081bfcd19e3fb0df87a63b762ac244 205 PANTHER PTHR23416 67 204 8.6E-28 T 13-09-2016 THL1_RS09855 47081bfcd19e3fb0df87a63b762ac244 205 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 155 187 2.6E-5 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS09855 47081bfcd19e3fb0df87a63b762ac244 205 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 119 153 0.002 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS25560 223bf518cfc137d31ee8419bc17775a5 279 PANTHER PTHR33643:SF1 1 276 1.3E-50 T 13-09-2016 THL1_RS25560 223bf518cfc137d31ee8419bc17775a5 279 Pfam PF01774 UreD urease accessory protein 57 252 1.6E-45 T 13-09-2016 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 THL1_RS25560 223bf518cfc137d31ee8419bc17775a5 279 Hamap MF_01384 Urease accessory protein UreD [ureD]. 14 263 28.752 T 13-09-2016 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 THL1_RS25560 223bf518cfc137d31ee8419bc17775a5 279 PANTHER PTHR33643 1 276 1.3E-50 T 13-09-2016 THL1_RS24760 4795d5c974a86ca9b4f162a71f77644b 124 SUPERFAMILY SSF54523 7 124 4.32E-23 T 13-09-2016 THL1_RS24760 4795d5c974a86ca9b4f162a71f77644b 124 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS24760 4795d5c974a86ca9b4f162a71f77644b 124 Gene3D G3DSA:3.30.700.10 7 68 1.8E-11 T 13-09-2016 THL1_RS24760 4795d5c974a86ca9b4f162a71f77644b 124 PRINTS PR00813 Bacterial general secretion pathway protein G signature 6 31 3.3E-8 T 13-09-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THL1_RS24760 4795d5c974a86ca9b4f162a71f77644b 124 PRINTS PR00813 Bacterial general secretion pathway protein G signature 42 60 3.3E-8 T 13-09-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THL1_RS24760 4795d5c974a86ca9b4f162a71f77644b 124 PANTHER PTHR30093:SF6 5 96 1.6E-23 T 13-09-2016 THL1_RS24760 4795d5c974a86ca9b4f162a71f77644b 124 PANTHER PTHR30093 5 96 1.6E-23 T 13-09-2016 THL1_RS24760 4795d5c974a86ca9b4f162a71f77644b 124 Pfam PF13633 Prokaryotic N-terminal methylation site 4 29 7.4E-12 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS24760 4795d5c974a86ca9b4f162a71f77644b 124 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 27 7.5E-10 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS17035 a675748f13c38f4735bc370b11c6521c 175 Gene3D G3DSA:2.10.109.10 133 173 2.0E-9 T 13-09-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain THL1_RS17035 a675748f13c38f4735bc370b11c6521c 175 Gene3D G3DSA:2.10.109.10 41 95 2.0E-9 T 13-09-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain THL1_RS17035 a675748f13c38f4735bc370b11c6521c 175 TIGRFAM TIGR02771 TraF_Ti: conjugative transfer signal peptidase TraF 17 170 3.8E-30 T 13-09-2016 IPR014139 Peptidase S26C, conjugative transfer signal peptidase TraF GO:0000746|GO:0042597 THL1_RS17035 a675748f13c38f4735bc370b11c6521c 175 SUPERFAMILY SSF51306 36 171 1.52E-23 T 13-09-2016 IPR015927 Peptidase S24/S26A/S26B/S26C THL1_RS17035 a675748f13c38f4735bc370b11c6521c 175 Pfam PF10502 Signal peptidase, peptidase S26 34 171 3.5E-52 T 13-09-2016 IPR019533 Peptidase S26 THL1_RS07375 d76fe408809909458877f87fcd8e7969 392 SUPERFAMILY SSF103473 8 389 1.44E-51 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS07375 d76fe408809909458877f87fcd8e7969 392 PANTHER PTHR23546:SF1 4 392 9.2E-45 T 13-09-2016 THL1_RS07375 d76fe408809909458877f87fcd8e7969 392 Gene3D G3DSA:1.20.1250.20 10 191 1.8E-27 T 13-09-2016 THL1_RS07375 d76fe408809909458877f87fcd8e7969 392 Gene3D G3DSA:1.20.1250.20 207 382 2.8E-13 T 13-09-2016 THL1_RS07375 d76fe408809909458877f87fcd8e7969 392 Pfam PF07690 Major Facilitator Superfamily 12 343 2.3E-33 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS07375 d76fe408809909458877f87fcd8e7969 392 PANTHER PTHR23546 4 392 9.2E-45 T 13-09-2016 THL1_RS11290 6d09e1c6542e4c1a2bd6c433fbfd15ae 474 PANTHER PTHR11699:SF109 1 474 1.3E-277 T 13-09-2016 IPR015657 Aminobutyraldehyde dehydrogenase KEGG: 00330+1.2.1.19|KEGG: 00410+1.2.1.19|MetaCyc: PWY-2|MetaCyc: PWY-3|UniPathway: UPA00188 THL1_RS11290 6d09e1c6542e4c1a2bd6c433fbfd15ae 474 Gene3D G3DSA:3.40.309.10 259 437 1.8E-60 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS11290 6d09e1c6542e4c1a2bd6c433fbfd15ae 474 Gene3D G3DSA:3.40.605.10 2 258 4.0E-98 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS11290 6d09e1c6542e4c1a2bd6c433fbfd15ae 474 SUPERFAMILY SSF53720 2 473 7.59E-160 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS11290 6d09e1c6542e4c1a2bd6c433fbfd15ae 474 Pfam PF00171 Aldehyde dehydrogenase family 12 470 1.3E-164 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS11290 6d09e1c6542e4c1a2bd6c433fbfd15ae 474 PANTHER PTHR11699 1 474 1.3E-277 T 13-09-2016 THL1_RS11290 6d09e1c6542e4c1a2bd6c433fbfd15ae 474 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 245 252 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 SUPERFAMILY SSF52833 1 100 8.61E-30 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS06710 ec114394647df7007fcab11ed484da87 518 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 344 364 - T 13-09-2016 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 314 332 2.3E-40 T 13-09-2016 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 467 489 2.3E-40 T 13-09-2016 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 441 457 2.3E-40 T 13-09-2016 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 374 2.3E-40 T 13-09-2016 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 214 233 2.3E-40 T 13-09-2016 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 PIRSF PIRSF000238 1 518 1.5E-264 T 13-09-2016 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 PANTHER PTHR22912 198 513 1.8E-207 T 13-09-2016 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 SUPERFAMILY SSF51905 202 513 8.64E-51 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 Gene3D G3DSA:3.50.50.60 211 331 6.4E-24 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 SUPERFAMILY SSF52833 105 196 1.27E-22 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS06710 ec114394647df7007fcab11ed484da87 518 Gene3D G3DSA:3.40.30.10 104 195 2.0E-35 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS06710 ec114394647df7007fcab11ed484da87 518 PANTHER PTHR22912:SF107 198 513 1.8E-207 T 13-09-2016 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 Gene3D G3DSA:3.50.50.60 437 515 1.2E-14 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 Pfam PF13192 Thioredoxin domain 124 190 7.9E-9 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS06710 ec114394647df7007fcab11ed484da87 518 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 212 503 3.3E-47 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 352 376 4.4E-66 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 337 349 4.4E-66 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 477 495 4.4E-66 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 265 275 4.4E-66 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 213 235 4.4E-66 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 315 323 4.4E-66 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 245 260 4.4E-66 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 404 420 4.4E-66 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 443 464 4.4E-66 T 13-09-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 516 2.1E-241 T 13-09-2016 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 Gene3D G3DSA:3.50.50.60 332 436 5.0E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS06710 ec114394647df7007fcab11ed484da87 518 Gene3D G3DSA:3.40.30.10 1 93 2.1E-32 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS17825 53a8ce5ee64f313ed5aba13ae0a1648f 259 Pfam PF01925 Sulfite exporter TauE/SafE 17 251 1.6E-42 T 13-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 THL1_RS17825 53a8ce5ee64f313ed5aba13ae0a1648f 259 PANTHER PTHR30269:SF25 9 257 3.1E-147 T 13-09-2016 THL1_RS17825 53a8ce5ee64f313ed5aba13ae0a1648f 259 PANTHER PTHR30269 9 257 3.1E-147 T 13-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 THL1_RS00070 f7d3c0184b7294cf8cc3f1f023884a85 183 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 3 178 4.0E-84 T 13-09-2016 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 THL1_RS00070 f7d3c0184b7294cf8cc3f1f023884a85 183 SUPERFAMILY SSF48150 1 181 1.33E-73 T 13-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 THL1_RS00070 f7d3c0184b7294cf8cc3f1f023884a85 183 PANTHER PTHR30037:SF4 1 183 8.0E-104 T 13-09-2016 THL1_RS00070 f7d3c0184b7294cf8cc3f1f023884a85 183 Gene3D G3DSA:1.10.340.30 2 178 1.2E-73 T 13-09-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 THL1_RS00070 f7d3c0184b7294cf8cc3f1f023884a85 183 PANTHER PTHR30037 1 183 8.0E-104 T 13-09-2016 THL1_RS00070 f7d3c0184b7294cf8cc3f1f023884a85 183 Pfam PF03352 Methyladenine glycosylase 6 177 1.4E-69 T 13-09-2016 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 THL1_RS26000 2bfd07315692d313180cb22d6acb8b4f 433 PIRSF PIRSF002744 11 420 5.6E-45 T 13-09-2016 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 THL1_RS26000 2bfd07315692d313180cb22d6acb8b4f 433 PANTHER PTHR30569 1 422 4.5E-41 T 13-09-2016 IPR030191 Cytosine permease GO:0015209|GO:0016021 THL1_RS26000 2bfd07315692d313180cb22d6acb8b4f 433 TIGRFAM TIGR02358 thia_cytX: putative hydroxymethylpyrimidine transporter CytX 23 411 1.5E-125 T 13-09-2016 IPR012732 Hydroxymethylpyrimidine transporter CytX THL1_RS26000 2bfd07315692d313180cb22d6acb8b4f 433 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 12 396 1.2E-23 T 13-09-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 THL1_RS23430 bcc5caea1fd0935016ea1dd4f6ebeeff 150 PANTHER PTHR35335 1 149 6.4E-40 T 13-09-2016 THL1_RS23430 bcc5caea1fd0935016ea1dd4f6ebeeff 150 PANTHER PTHR35335:SF1 1 149 6.4E-40 T 13-09-2016 THL1_RS23430 bcc5caea1fd0935016ea1dd4f6ebeeff 150 Pfam PF04186 FxsA cytoplasmic membrane protein 7 113 7.2E-36 T 13-09-2016 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 THL1_RS17010 99716ab88a25e233afa6e92c65c76c7c 373 PIRSF PIRSF038925 7 365 7.8E-114 T 13-09-2016 IPR026287 Adenosine monophosphate-protein transferase THL1_RS17010 99716ab88a25e233afa6e92c65c76c7c 373 Pfam PF02661 Fic/DOC family 151 218 6.4E-16 T 13-09-2016 IPR003812 Fido domain THL1_RS17010 99716ab88a25e233afa6e92c65c76c7c 373 SUPERFAMILY SSF140931 99 282 4.71E-32 T 13-09-2016 IPR003812 Fido domain THL1_RS17010 99716ab88a25e233afa6e92c65c76c7c 373 PANTHER PTHR13504 13 371 3.0E-203 T 13-09-2016 THL1_RS17010 99716ab88a25e233afa6e92c65c76c7c 373 Gene3D G3DSA:1.10.3290.10 34 288 1.1E-51 T 13-09-2016 IPR003812 Fido domain THL1_RS17010 99716ab88a25e233afa6e92c65c76c7c 373 Pfam PF13784 Fic/DOC family N-terminal 32 113 2.1E-23 T 13-09-2016 IPR025758 Fic/DOC N-terminal THL1_RS17010 99716ab88a25e233afa6e92c65c76c7c 373 PANTHER PTHR13504:SF35 13 371 3.0E-203 T 13-09-2016 THL1_RS12905 b79ed473a9eff1d36d9a3ae6e052fcca 105 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 16 85 2.3E-11 T 13-09-2016 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 THL1_RS27640 2e4ca49f5c43d124cfd8e1667f87393e 859 Gene3D G3DSA:3.40.50.300 212 283 4.9E-4 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27640 2e4ca49f5c43d124cfd8e1667f87393e 859 SUPERFAMILY SSF48452 598 682 8.71E-6 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS27640 2e4ca49f5c43d124cfd8e1667f87393e 859 SUPERFAMILY SSF52540 202 415 5.2E-11 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS27640 2e4ca49f5c43d124cfd8e1667f87393e 859 Gene3D G3DSA:1.25.40.10 588 661 2.8E-6 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS05325 00699b328f5f35f6f98bee03e205d6e0 284 PANTHER PTHR23088:SF27 1 270 7.0E-104 T 13-09-2016 THL1_RS05325 00699b328f5f35f6f98bee03e205d6e0 284 SUPERFAMILY SSF56317 1 267 9.03E-75 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS05325 00699b328f5f35f6f98bee03e205d6e0 284 Gene3D G3DSA:3.60.110.10 1 270 3.2E-77 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS05325 00699b328f5f35f6f98bee03e205d6e0 284 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 153 173 - T 13-09-2016 IPR001110 Uncharacterised protein family UPF0012, conserved site THL1_RS05325 00699b328f5f35f6f98bee03e205d6e0 284 PANTHER PTHR23088 1 270 7.0E-104 T 13-09-2016 THL1_RS05325 00699b328f5f35f6f98bee03e205d6e0 284 Pfam PF00795 Carbon-nitrogen hydrolase 3 253 2.2E-48 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS19950 6eb38762f6cdeeaca27330b666b9efd7 185 PANTHER PTHR11080 4 180 9.3E-53 T 13-09-2016 THL1_RS19950 6eb38762f6cdeeaca27330b666b9efd7 185 Gene3D G3DSA:3.40.50.850 1 183 1.1E-51 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS19950 6eb38762f6cdeeaca27330b666b9efd7 185 PANTHER PTHR11080:SF35 4 180 9.3E-53 T 13-09-2016 THL1_RS19950 6eb38762f6cdeeaca27330b666b9efd7 185 Pfam PF00857 Isochorismatase family 5 177 1.9E-36 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS19950 6eb38762f6cdeeaca27330b666b9efd7 185 SUPERFAMILY SSF52499 2 182 4.97E-52 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS12495 db0729fd99ef993a99730e240a179da3 186 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 69 3.2E-19 T 13-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THL1_RS12495 db0729fd99ef993a99730e240a179da3 186 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 47 69 - T 13-09-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THL1_RS12495 db0729fd99ef993a99730e240a179da3 186 PIRSF PIRSF000847 1 186 1.5E-51 T 13-09-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 THL1_RS12495 db0729fd99ef993a99730e240a179da3 186 PANTHER PTHR14269 1 179 5.8E-91 T 13-09-2016 THL1_RS12495 db0729fd99ef993a99730e240a179da3 186 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 177 2.4E-57 T 13-09-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 THL1_RS12495 db0729fd99ef993a99730e240a179da3 186 PANTHER PTHR14269:SF13 1 179 5.8E-91 T 13-09-2016 THL1_RS16945 09269d0e791fe049559ef16709e9c8cb 342 PANTHER PTHR38457:SF1 1 340 1.6E-50 T 13-09-2016 THL1_RS16945 09269d0e791fe049559ef16709e9c8cb 342 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 4 157 4.6E-38 T 13-09-2016 IPR017516 AbrB duplication THL1_RS16945 09269d0e791fe049559ef16709e9c8cb 342 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 185 335 8.0E-40 T 13-09-2016 IPR017516 AbrB duplication THL1_RS16945 09269d0e791fe049559ef16709e9c8cb 342 Pfam PF05145 Putative ammonia monooxygenase 29 337 5.9E-88 T 13-09-2016 IPR007820 AbrB family GO:0010468|GO:0016021 THL1_RS16945 09269d0e791fe049559ef16709e9c8cb 342 PIRSF PIRSF038991 1 342 3.9E-68 T 13-09-2016 IPR007820 AbrB family GO:0010468|GO:0016021 THL1_RS16945 09269d0e791fe049559ef16709e9c8cb 342 PANTHER PTHR38457 1 340 1.6E-50 T 13-09-2016 THL1_RS00595 86acd35f2f361c01bc520437e1319bfa 458 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 121 149 0.0055 T 13-09-2016 IPR013431 Delta-60 repeat THL1_RS00595 86acd35f2f361c01bc520437e1319bfa 458 Pfam PF17164 Domain of unknown function (DUF5122) beta-propeller 328 357 0.0013 T 13-09-2016 IPR013431 Delta-60 repeat THL1_RS00595 86acd35f2f361c01bc520437e1319bfa 458 SUPERFAMILY SSF101898 51 283 8.89E-15 T 13-09-2016 THL1_RS00595 86acd35f2f361c01bc520437e1319bfa 458 Gene3D G3DSA:2.120.10.30 116 385 2.3E-12 T 13-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like THL1_RS24190 fb9b63df9bd73293dfb88272f3e9a8c8 163 SUPERFAMILY SSF55021 79 161 5.49E-26 T 13-09-2016 THL1_RS24190 fb9b63df9bd73293dfb88272f3e9a8c8 163 PANTHER PTHR30239 1 159 2.3E-88 T 13-09-2016 THL1_RS24190 fb9b63df9bd73293dfb88272f3e9a8c8 163 Gene3D G3DSA:3.30.70.1150 83 161 2.3E-29 T 13-09-2016 THL1_RS24190 fb9b63df9bd73293dfb88272f3e9a8c8 163 Pfam PF10369 Small subunit of acetolactate synthase 84 157 2.8E-26 T 13-09-2016 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS24190 fb9b63df9bd73293dfb88272f3e9a8c8 163 Pfam PF13710 ACT domain 12 72 3.3E-15 T 13-09-2016 THL1_RS24190 fb9b63df9bd73293dfb88272f3e9a8c8 163 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 158 2.7E-62 T 13-09-2016 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS24190 fb9b63df9bd73293dfb88272f3e9a8c8 163 Gene3D G3DSA:3.30.70.260 1 78 2.7E-34 T 13-09-2016 THL1_RS24190 fb9b63df9bd73293dfb88272f3e9a8c8 163 SUPERFAMILY SSF55021 1 73 5.39E-21 T 13-09-2016 THL1_RS24190 fb9b63df9bd73293dfb88272f3e9a8c8 163 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 1.0E-36 T 13-09-2016 THL1_RS01975 e9638500c051c0024ea81f31c864628c 417 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 13-09-2016 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 THL1_RS01975 e9638500c051c0024ea81f31c864628c 417 Pfam PF00464 Serine hydroxymethyltransferase 9 386 4.7E-184 T 13-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 THL1_RS01975 e9638500c051c0024ea81f31c864628c 417 Gene3D G3DSA:3.40.640.10 37 284 4.5E-109 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS01975 e9638500c051c0024ea81f31c864628c 417 PIRSF PIRSF000412 1 414 2.1E-169 T 13-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 THL1_RS01975 e9638500c051c0024ea81f31c864628c 417 Gene3D G3DSA:3.90.1150.10 285 416 1.8E-53 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS01975 e9638500c051c0024ea81f31c864628c 417 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 53.376 T 13-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 THL1_RS01975 e9638500c051c0024ea81f31c864628c 417 PANTHER PTHR11680 1 416 0.0 T 13-09-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 THL1_RS01975 e9638500c051c0024ea81f31c864628c 417 SUPERFAMILY SSF53383 5 416 2.28E-184 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS01975 e9638500c051c0024ea81f31c864628c 417 PANTHER PTHR11680:SF9 1 416 0.0 T 13-09-2016 THL1_RS20930 f9f05fc29a6e9c949b644506a9733d01 487 SUPERFAMILY SSF53901 150 292 7.58E-13 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20930 f9f05fc29a6e9c949b644506a9733d01 487 SUPERFAMILY SSF50249 363 458 4.63E-7 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS20930 f9f05fc29a6e9c949b644506a9733d01 487 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 403 458 3.2E-8 T 13-09-2016 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal THL1_RS20930 f9f05fc29a6e9c949b644506a9733d01 487 SUPERFAMILY SSF53901 1 162 7.97E-20 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20930 f9f05fc29a6e9c949b644506a9733d01 487 Gene3D G3DSA:3.40.47.10 157 293 7.9E-14 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS20930 f9f05fc29a6e9c949b644506a9733d01 487 Gene3D G3DSA:3.40.47.10 1 156 1.8E-10 T 13-09-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 THL1_RS17730 14eee9b266de6b8cea18148f51342294 80 Pfam PF06906 Protein of unknown function (DUF1272) 1 57 1.4E-31 T 13-09-2016 IPR010696 Protein of unknown function DUF1272 THL1_RS16170 07e3e36c0bcef5e865a16861b12a8037 728 Pfam PF12571 Phage tail-collar fibre protein 8 104 4.7E-11 T 13-09-2016 IPR022225 Phage tail fibre protein THL1_RS18055 a304e902a5badaa7e45acb9a133009a0 287 Gene3D G3DSA:3.40.50.620 5 117 2.4E-7 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS18055 a304e902a5badaa7e45acb9a133009a0 287 SUPERFAMILY SSF52402 133 275 1.67E-14 T 13-09-2016 THL1_RS18055 a304e902a5badaa7e45acb9a133009a0 287 PANTHER PTHR31964 117 282 2.9E-48 T 13-09-2016 THL1_RS18055 a304e902a5badaa7e45acb9a133009a0 287 Gene3D G3DSA:3.40.50.620 118 272 4.2E-16 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS18055 a304e902a5badaa7e45acb9a133009a0 287 Pfam PF00582 Universal stress protein family 133 272 5.4E-13 T 13-09-2016 IPR006016 UspA GO:0006950 THL1_RS18055 a304e902a5badaa7e45acb9a133009a0 287 PANTHER PTHR31964:SF41 117 282 2.9E-48 T 13-09-2016 THL1_RS18055 a304e902a5badaa7e45acb9a133009a0 287 SUPERFAMILY SSF52402 2 124 2.6E-12 T 13-09-2016 THL1_RS27255 cabf05becabaa523c49da8c7fe65bdb9 184 Pfam PF03695 Uncharacterised protein family (UPF0149) 11 172 2.8E-31 T 13-09-2016 IPR011978 Uncharacterised protein family UPF0149 THL1_RS27255 cabf05becabaa523c49da8c7fe65bdb9 184 PANTHER PTHR37528 1 184 8.3E-32 T 13-09-2016 THL1_RS27255 cabf05becabaa523c49da8c7fe65bdb9 184 Hamap MF_00346 UPF0149 protein YgfB [ygfB]. 4 182 29.676 T 13-09-2016 IPR011978 Uncharacterised protein family UPF0149 THL1_RS27255 cabf05becabaa523c49da8c7fe65bdb9 184 SUPERFAMILY SSF101327 6 171 8.37E-40 T 13-09-2016 IPR011978 Uncharacterised protein family UPF0149 THL1_RS12040 908de9c13b9e7767169a4355d56ad0d9 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 93 1.0E-7 T 13-09-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THL1_RS12040 908de9c13b9e7767169a4355d56ad0d9 340 PANTHER PTHR11695 16 340 1.9E-89 T 13-09-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 THL1_RS12040 908de9c13b9e7767169a4355d56ad0d9 340 SUPERFAMILY SSF50129 3 152 2.74E-28 T 13-09-2016 IPR011032 GroES-like THL1_RS12040 908de9c13b9e7767169a4355d56ad0d9 340 Gene3D G3DSA:3.90.180.10 3 141 2.3E-25 T 13-09-2016 IPR011032 GroES-like THL1_RS12040 908de9c13b9e7767169a4355d56ad0d9 340 SUPERFAMILY SSF51735 119 274 1.15E-29 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS12040 908de9c13b9e7767169a4355d56ad0d9 340 Gene3D G3DSA:3.40.50.720 142 307 1.7E-33 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS12040 908de9c13b9e7767169a4355d56ad0d9 340 SMART SM00829 11 336 1.8E-11 T 13-09-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THL1_RS12040 908de9c13b9e7767169a4355d56ad0d9 340 PANTHER PTHR11695:SF605 16 340 1.9E-89 T 13-09-2016 THL1_RS12040 908de9c13b9e7767169a4355d56ad0d9 340 Pfam PF00107 Zinc-binding dehydrogenase 163 267 1.3E-16 T 13-09-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THL1_RS07450 aeaacedab68e58ef4454a61c2dd0b6e2 224 Pfam PF01493 GXGXG motif 30 187 2.6E-13 T 13-09-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 THL1_RS07450 aeaacedab68e58ef4454a61c2dd0b6e2 224 PIRSF PIRSF006519 1 224 6.3E-83 T 13-09-2016 IPR012061 Glutamate synthase, large subunit domain 3 stand-alone protein THL1_RS07450 aeaacedab68e58ef4454a61c2dd0b6e2 224 Gene3D G3DSA:2.160.20.60 26 194 9.3E-35 T 13-09-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 THL1_RS07450 aeaacedab68e58ef4454a61c2dd0b6e2 224 SUPERFAMILY SSF69336 4 194 1.03E-42 T 13-09-2016 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 THL1_RS04495 f51983cb4bfb3360e8f34d389d4f88f3 159 PANTHER PTHR35458:SF2 4 156 2.2E-56 T 13-09-2016 THL1_RS04495 f51983cb4bfb3360e8f34d389d4f88f3 159 Gene3D G3DSA:3.40.50.1010 2 152 8.2E-42 T 13-09-2016 IPR029060 PIN domain-like THL1_RS04495 f51983cb4bfb3360e8f34d389d4f88f3 159 PANTHER PTHR35458 4 156 2.2E-56 T 13-09-2016 THL1_RS04495 f51983cb4bfb3360e8f34d389d4f88f3 159 Pfam PF01936 NYN domain 4 150 1.8E-35 T 13-09-2016 IPR021139 NYN domain, limkain-b1-type THL1_RS20905 fafbf37108df82521ebe3bf3f6264352 285 SUPERFAMILY SSF54637 170 281 2.82E-18 T 13-09-2016 IPR029069 HotDog domain THL1_RS20905 fafbf37108df82521ebe3bf3f6264352 285 Pfam PF01575 MaoC like domain 163 253 6.3E-5 T 13-09-2016 IPR002539 MaoC-like domain THL1_RS20905 fafbf37108df82521ebe3bf3f6264352 285 PANTHER PTHR28152 46 284 1.8E-57 T 13-09-2016 THL1_RS20905 fafbf37108df82521ebe3bf3f6264352 285 PANTHER PTHR28152:SF1 46 284 1.8E-57 T 13-09-2016 THL1_RS20905 fafbf37108df82521ebe3bf3f6264352 285 Pfam PF13452 N-terminal half of MaoC dehydratase 77 137 9.6E-8 T 13-09-2016 THL1_RS20905 fafbf37108df82521ebe3bf3f6264352 285 Gene3D G3DSA:3.10.129.10 159 279 9.0E-13 T 13-09-2016 IPR029069 HotDog domain THL1_RS03585 5fa50cb9079f239ad48b957e27998fb0 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 43.691 T 13-09-2016 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03585 5fa50cb9079f239ad48b957e27998fb0 179 Gene3D G3DSA:3.30.1440.10 1 179 8.5E-77 T 13-09-2016 IPR022803 Ribosomal protein L5 domain THL1_RS03585 5fa50cb9079f239ad48b957e27998fb0 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 13-09-2016 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS03585 5fa50cb9079f239ad48b957e27998fb0 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 3.6E-40 T 13-09-2016 IPR031309 Ribosomal protein L5, C-terminal THL1_RS03585 5fa50cb9079f239ad48b957e27998fb0 179 PANTHER PTHR11994 1 178 3.2E-93 T 13-09-2016 THL1_RS03585 5fa50cb9079f239ad48b957e27998fb0 179 SUPERFAMILY SSF55282 3 179 6.59E-77 T 13-09-2016 IPR022803 Ribosomal protein L5 domain THL1_RS03585 5fa50cb9079f239ad48b957e27998fb0 179 Pfam PF00281 Ribosomal protein L5 24 80 7.0E-27 T 13-09-2016 IPR031310 Ribosomal protein L5, N-terminal THL1_RS03585 5fa50cb9079f239ad48b957e27998fb0 179 PIRSF PIRSF002161 1 179 4.6E-63 T 13-09-2016 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 THL1_RS00295 a77264edac2ff5e9f35f7f4e77038325 211 PANTHER PTHR12151:SF0 4 207 4.5E-63 T 13-09-2016 THL1_RS00295 a77264edac2ff5e9f35f7f4e77038325 211 PANTHER PTHR12151 4 207 4.5E-63 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS00295 a77264edac2ff5e9f35f7f4e77038325 211 Pfam PF02630 SCO1/SenC 54 184 1.2E-32 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS00295 a77264edac2ff5e9f35f7f4e77038325 211 Gene3D G3DSA:3.40.30.10 11 207 6.1E-51 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS00295 a77264edac2ff5e9f35f7f4e77038325 211 SUPERFAMILY SSF52833 50 206 2.68E-45 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS21260 c4efc79d51c183d8f89bdc3adb0bf849 102 PANTHER PTHR31885 1 77 4.7E-15 T 13-09-2016 THL1_RS21260 c4efc79d51c183d8f89bdc3adb0bf849 102 Pfam PF07947 YhhN-like protein 2 77 1.5E-19 T 13-09-2016 IPR012506 YhhN-like GO:0016021 THL1_RS25715 5efb5e6bd815f9f89a5b8cec6d3a0852 149 TIGRFAM TIGR02695 azurin: azurin 23 147 1.4E-61 T 13-09-2016 IPR014068 Azurin, proteobacteria THL1_RS25715 5efb5e6bd815f9f89a5b8cec6d3a0852 149 SUPERFAMILY SSF49503 21 147 6.77E-47 T 13-09-2016 IPR008972 Cupredoxin THL1_RS25715 5efb5e6bd815f9f89a5b8cec6d3a0852 149 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 21 147 2.2E-30 T 13-09-2016 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 THL1_RS25715 5efb5e6bd815f9f89a5b8cec6d3a0852 149 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 27 145 3.0E-49 T 13-09-2016 THL1_RS25715 5efb5e6bd815f9f89a5b8cec6d3a0852 149 Gene3D G3DSA:2.60.40.420 22 147 4.7E-56 T 13-09-2016 IPR008972 Cupredoxin THL1_RS25715 5efb5e6bd815f9f89a5b8cec6d3a0852 149 PANTHER PTHR38439:SF2 2 149 5.6E-53 T 13-09-2016 THL1_RS25715 5efb5e6bd815f9f89a5b8cec6d3a0852 149 PANTHER PTHR38439 2 149 5.6E-53 T 13-09-2016 THL1_RS25715 5efb5e6bd815f9f89a5b8cec6d3a0852 149 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 125 141 - T 13-09-2016 IPR028871 Blue (type 1) copper protein, binding site THL1_RS15745 db619a3ff261532959270f323ac696ee 93 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 4 93 6.2E-41 T 13-09-2016 IPR009359 Phenylacetic acid degradation B UniPathway: UPA00930 THL1_RS15745 db619a3ff261532959270f323ac696ee 93 PIRSF PIRSF030200 1 93 7.0E-43 T 13-09-2016 IPR009359 Phenylacetic acid degradation B UniPathway: UPA00930 THL1_RS15745 db619a3ff261532959270f323ac696ee 93 Pfam PF06243 Phenylacetic acid degradation B 3 89 5.5E-39 T 13-09-2016 IPR009359 Phenylacetic acid degradation B UniPathway: UPA00930 THL1_RS06515 d280e1f629973d190d3807d4d1e435df 329 PANTHER PTHR30457 10 251 9.5E-32 T 13-09-2016 THL1_RS06515 d280e1f629973d190d3807d4d1e435df 329 Gene3D G3DSA:3.40.1210.10 23 322 1.5E-46 T 13-09-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 THL1_RS06515 d280e1f629973d190d3807d4d1e435df 329 SUPERFAMILY SSF64167 23 324 4.45E-39 T 13-09-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 THL1_RS06515 d280e1f629973d190d3807d4d1e435df 329 Pfam PF01975 Survival protein SurE 25 257 3.7E-40 T 13-09-2016 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185 THL1_RS17760 fbfdb2b2a1ce18a1badbe645cee28028 346 PIRSF PIRSF006004 1 344 2.7E-90 T 13-09-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS17760 fbfdb2b2a1ce18a1badbe645cee28028 346 Pfam PF04055 Radical SAM superfamily 102 261 1.8E-11 T 13-09-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 THL1_RS17760 fbfdb2b2a1ce18a1badbe645cee28028 346 PANTHER PTHR30544:SF5 1 331 5.3E-100 T 13-09-2016 THL1_RS17760 fbfdb2b2a1ce18a1badbe645cee28028 346 SUPERFAMILY SSF102114 100 305 2.49E-11 T 13-09-2016 THL1_RS17760 fbfdb2b2a1ce18a1badbe645cee28028 346 PANTHER PTHR30544 1 331 5.3E-100 T 13-09-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 THL1_RS17760 fbfdb2b2a1ce18a1badbe645cee28028 346 Gene3D G3DSA:3.20.20.70 100 316 7.8E-12 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS25435 1772d056c628560121047c80eecb719d 174 PIRSF PIRSF017340 8 174 1.8E-71 T 13-09-2016 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 THL1_RS25435 1772d056c628560121047c80eecb719d 174 PANTHER PTHR22769 16 170 3.5E-35 T 13-09-2016 THL1_RS25435 1772d056c628560121047c80eecb719d 174 SUPERFAMILY SSF55811 17 172 3.11E-35 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS25435 1772d056c628560121047c80eecb719d 174 PANTHER PTHR22769:SF25 16 170 3.5E-35 T 13-09-2016 THL1_RS25435 1772d056c628560121047c80eecb719d 174 Pfam PF00293 NUDIX domain 45 155 2.1E-16 T 13-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 THL1_RS25435 1772d056c628560121047c80eecb719d 174 Gene3D G3DSA:3.90.79.10 11 172 1.3E-51 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS24195 11ec72b0b02ba1b1cd52a60a0156bd6d 574 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 396 545 3.0E-49 T 13-09-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THL1_RS24195 11ec72b0b02ba1b1cd52a60a0156bd6d 574 Gene3D G3DSA:3.40.50.1220 190 353 4.8E-65 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS24195 11ec72b0b02ba1b1cd52a60a0156bd6d 574 Gene3D G3DSA:3.40.50.970 4 176 1.5E-74 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS24195 11ec72b0b02ba1b1cd52a60a0156bd6d 574 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 4 569 2.6E-263 T 13-09-2016 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 THL1_RS24195 11ec72b0b02ba1b1cd52a60a0156bd6d 574 Gene3D G3DSA:3.40.50.970 354 557 1.5E-72 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS24195 11ec72b0b02ba1b1cd52a60a0156bd6d 574 SUPERFAMILY SSF52518 374 567 1.46E-66 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS24195 11ec72b0b02ba1b1cd52a60a0156bd6d 574 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 165 1.4E-60 T 13-09-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 THL1_RS24195 11ec72b0b02ba1b1cd52a60a0156bd6d 574 PANTHER PTHR18968:SF116 4 574 0.0 T 13-09-2016 THL1_RS24195 11ec72b0b02ba1b1cd52a60a0156bd6d 574 SUPERFAMILY SSF52467 189 359 7.24E-65 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS24195 11ec72b0b02ba1b1cd52a60a0156bd6d 574 SUPERFAMILY SSF52518 4 179 8.42E-66 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS24195 11ec72b0b02ba1b1cd52a60a0156bd6d 574 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 330 1.1E-44 T 13-09-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 THL1_RS24195 11ec72b0b02ba1b1cd52a60a0156bd6d 574 PANTHER PTHR18968 4 574 0.0 T 13-09-2016 THL1_RS20485 e0a01d673476cb27f2617f5e448e9954 384 Gene3D G3DSA:3.20.20.30 27 375 9.5E-63 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS20485 e0a01d673476cb27f2617f5e448e9954 384 SUPERFAMILY SSF51679 29 370 4.71E-50 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS20485 e0a01d673476cb27f2617f5e448e9954 384 PANTHER PTHR30137 30 124 1.2E-12 T 13-09-2016 THL1_RS20485 e0a01d673476cb27f2617f5e448e9954 384 PANTHER PTHR30137 140 384 1.2E-12 T 13-09-2016 THL1_RS20485 e0a01d673476cb27f2617f5e448e9954 384 Pfam PF00296 Luciferase-like monooxygenase 33 307 2.0E-23 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS20555 e0a01d673476cb27f2617f5e448e9954 384 Gene3D G3DSA:3.20.20.30 27 375 9.5E-63 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS20555 e0a01d673476cb27f2617f5e448e9954 384 SUPERFAMILY SSF51679 29 370 4.71E-50 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS20555 e0a01d673476cb27f2617f5e448e9954 384 PANTHER PTHR30137 30 124 1.2E-12 T 13-09-2016 THL1_RS20555 e0a01d673476cb27f2617f5e448e9954 384 PANTHER PTHR30137 140 384 1.2E-12 T 13-09-2016 THL1_RS20555 e0a01d673476cb27f2617f5e448e9954 384 Pfam PF00296 Luciferase-like monooxygenase 33 307 2.0E-23 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS20750 d53a0a4cbd192f673c139a27574ed8c8 324 SMART SM00382 41 201 0.0011 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS20750 d53a0a4cbd192f673c139a27574ed8c8 324 Gene3D G3DSA:3.40.50.300 38 175 1.6E-8 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS20750 d53a0a4cbd192f673c139a27574ed8c8 324 SUPERFAMILY SSF52540 18 275 4.15E-17 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS20750 d53a0a4cbd192f673c139a27574ed8c8 324 Pfam PF05621 Bacterial TniB protein 23 260 2.0E-21 T 13-09-2016 IPR008868 Bacterial TniB THL1_RS02975 8fb077827ae1b18e06497f3911adfecb 351 SMART SM00448 1 116 1.7E-30 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02975 8fb077827ae1b18e06497f3911adfecb 351 PANTHER PTHR24421 1 342 2.5E-73 T 13-09-2016 THL1_RS02975 8fb077827ae1b18e06497f3911adfecb 351 Gene3D G3DSA:3.40.50.180 155 343 9.9E-62 T 13-09-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS02975 8fb077827ae1b18e06497f3911adfecb 351 SUPERFAMILY SSF52738 158 340 2.62E-55 T 13-09-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS02975 8fb077827ae1b18e06497f3911adfecb 351 Pfam PF00072 Response regulator receiver domain 3 108 2.5E-24 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02975 8fb077827ae1b18e06497f3911adfecb 351 SUPERFAMILY SSF52172 1 132 3.84E-33 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS02975 8fb077827ae1b18e06497f3911adfecb 351 PIRSF PIRSF000876 1 347 8.1E-88 T 13-09-2016 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS02975 8fb077827ae1b18e06497f3911adfecb 351 Pfam PF01339 CheB methylesterase 163 338 4.9E-51 T 13-09-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS02975 8fb077827ae1b18e06497f3911adfecb 351 Gene3D G3DSA:3.40.50.2300 1 121 5.5E-33 T 13-09-2016 THL1_RS02975 8fb077827ae1b18e06497f3911adfecb 351 PANTHER PTHR24421:SF16 1 342 2.5E-73 T 13-09-2016 THL1_RS00330 c46e01da764a2870f094283ab80aadeb 266 Pfam PF00005 ABC transporter 21 149 2.6E-26 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS00330 c46e01da764a2870f094283ab80aadeb 266 PANTHER PTHR24220:SF466 7 243 2.2E-103 T 13-09-2016 THL1_RS00330 c46e01da764a2870f094283ab80aadeb 266 PANTHER PTHR24220 7 243 2.2E-103 T 13-09-2016 THL1_RS00330 c46e01da764a2870f094283ab80aadeb 266 ProSitePatterns PS00211 ABC transporters family signature. 122 136 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS00330 c46e01da764a2870f094283ab80aadeb 266 SUPERFAMILY SSF52540 3 213 1.14E-54 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00330 c46e01da764a2870f094283ab80aadeb 266 SMART SM00382 30 199 5.5E-10 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS00330 c46e01da764a2870f094283ab80aadeb 266 Gene3D G3DSA:3.40.50.300 2 211 5.2E-54 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS13435 e3b86dbca0750692d8b3ce6c6d5fcfb0 316 SUPERFAMILY SSF56024 38 135 4.71E-7 T 13-09-2016 THL1_RS13435 e3b86dbca0750692d8b3ce6c6d5fcfb0 316 Gene3D G3DSA:3.30.870.10 85 134 3.8E-4 T 13-09-2016 THL1_RS20675 80f916e889bf05047bd088a9a5146459 72 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 1 64 2.5E-8 T 13-09-2016 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 THL1_RS16595 3f10e3a5cf6ed8bab66ce11725e39326 247 PANTHER PTHR30050:SF6 1 241 7.1E-55 T 13-09-2016 THL1_RS16595 3f10e3a5cf6ed8bab66ce11725e39326 247 Gene3D G3DSA:3.40.50.300 55 231 3.1E-24 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16595 3f10e3a5cf6ed8bab66ce11725e39326 247 PIRSF PIRSF003073 3 247 2.2E-62 T 13-09-2016 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein THL1_RS16595 3f10e3a5cf6ed8bab66ce11725e39326 247 PANTHER PTHR30050 1 241 7.1E-55 T 13-09-2016 THL1_RS16595 3f10e3a5cf6ed8bab66ce11725e39326 247 Pfam PF08483 IstB-like ATP binding N-terminal 25 53 5.9E-5 T 13-09-2016 IPR013690 IstB-like ATP binding N-terminal THL1_RS16595 3f10e3a5cf6ed8bab66ce11725e39326 247 SUPERFAMILY SSF52540 93 238 1.44E-19 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16595 3f10e3a5cf6ed8bab66ce11725e39326 247 Pfam PF01695 IstB-like ATP binding protein 55 231 1.2E-51 T 13-09-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 THL1_RS22805 fb86a115a5d8be2a6c80fbc4ba598052 284 Gene3D G3DSA:3.20.20.410 3 272 4.7E-69 T 13-09-2016 IPR002763 Protein of unknown function DUF72 THL1_RS22805 fb86a115a5d8be2a6c80fbc4ba598052 284 Pfam PF01904 Protein of unknown function DUF72 21 259 4.2E-52 T 13-09-2016 IPR002763 Protein of unknown function DUF72 THL1_RS22805 fb86a115a5d8be2a6c80fbc4ba598052 284 PANTHER PTHR30348 5 270 6.9E-79 T 13-09-2016 THL1_RS22805 fb86a115a5d8be2a6c80fbc4ba598052 284 PANTHER PTHR30348:SF3 5 270 6.9E-79 T 13-09-2016 THL1_RS22805 fb86a115a5d8be2a6c80fbc4ba598052 284 SUPERFAMILY SSF117396 2 261 6.02E-69 T 13-09-2016 IPR002763 Protein of unknown function DUF72 THL1_RS28435 d37a8dc04944ee0347bde9b63ff41437 178 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 8 176 3.8E-47 T 13-09-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 THL1_RS28435 d37a8dc04944ee0347bde9b63ff41437 178 Gene3D G3DSA:1.10.520.20 2 106 1.1E-31 T 13-09-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain THL1_RS28435 d37a8dc04944ee0347bde9b63ff41437 178 PRINTS PR00125 ATP synthase delta subunit signature 86 100 3.3E-24 T 13-09-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 THL1_RS28435 d37a8dc04944ee0347bde9b63ff41437 178 PRINTS PR00125 ATP synthase delta subunit signature 7 26 3.3E-24 T 13-09-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 THL1_RS28435 d37a8dc04944ee0347bde9b63ff41437 178 PRINTS PR00125 ATP synthase delta subunit signature 136 151 3.3E-24 T 13-09-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 THL1_RS28435 d37a8dc04944ee0347bde9b63ff41437 178 PRINTS PR00125 ATP synthase delta subunit signature 151 169 3.3E-24 T 13-09-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 THL1_RS28435 d37a8dc04944ee0347bde9b63ff41437 178 PRINTS PR00125 ATP synthase delta subunit signature 75 86 3.3E-24 T 13-09-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 THL1_RS28435 d37a8dc04944ee0347bde9b63ff41437 178 SUPERFAMILY SSF47928 3 105 1.44E-23 T 13-09-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain THL1_RS28435 d37a8dc04944ee0347bde9b63ff41437 178 PANTHER PTHR11910 8 177 4.6E-49 T 13-09-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 THL1_RS28435 d37a8dc04944ee0347bde9b63ff41437 178 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 176 5.1E-53 T 13-09-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 THL1_RS28435 d37a8dc04944ee0347bde9b63ff41437 178 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 178 19.196 T 13-09-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 THL1_RS25325 6f7be26d72cf9c480afb763b3471bde0 244 Pfam PF14559 Tetratricopeptide repeat 111 170 5.8E-6 T 13-09-2016 THL1_RS25325 6f7be26d72cf9c480afb763b3471bde0 244 Gene3D G3DSA:1.25.40.10 34 188 1.8E-16 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS25325 6f7be26d72cf9c480afb763b3471bde0 244 SUPERFAMILY SSF48452 71 187 3.04E-13 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS25325 6f7be26d72cf9c480afb763b3471bde0 244 SMART SM00028 130 163 11.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS25325 6f7be26d72cf9c480afb763b3471bde0 244 SMART SM00028 96 129 2.2 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS08480 172e73b866b840515271c5508e8828a3 487 PANTHER PTHR11699 16 484 4.0E-221 T 13-09-2016 THL1_RS08480 172e73b866b840515271c5508e8828a3 487 Gene3D G3DSA:3.40.309.10 271 458 8.1E-70 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS08480 172e73b866b840515271c5508e8828a3 487 Gene3D G3DSA:3.40.605.10 14 270 2.6E-95 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS08480 172e73b866b840515271c5508e8828a3 487 Pfam PF00171 Aldehyde dehydrogenase family 26 483 3.0E-170 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS08480 172e73b866b840515271c5508e8828a3 487 SUPERFAMILY SSF53720 9 485 6.02E-167 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS08480 172e73b866b840515271c5508e8828a3 487 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 285 296 - T 13-09-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 THL1_RS17910 2ccc18afaef26c0a1fca2473f065e7b9 259 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 2 259 44.367 T 13-09-2016 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386|UniPathway: UPA00619 THL1_RS17910 2ccc18afaef26c0a1fca2473f065e7b9 259 PANTHER PTHR11935:SF7 1 259 4.4E-91 T 13-09-2016 THL1_RS17910 2ccc18afaef26c0a1fca2473f065e7b9 259 SUPERFAMILY SSF56281 3 259 7.72E-75 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS17910 2ccc18afaef26c0a1fca2473f065e7b9 259 PIRSF PIRSF005457 1 259 1.1E-102 T 13-09-2016 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386|UniPathway: UPA00619 THL1_RS17910 2ccc18afaef26c0a1fca2473f065e7b9 259 PANTHER PTHR11935 1 259 4.4E-91 T 13-09-2016 THL1_RS17910 2ccc18afaef26c0a1fca2473f065e7b9 259 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 4 259 5.0E-104 T 13-09-2016 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386|UniPathway: UPA00619 THL1_RS17910 2ccc18afaef26c0a1fca2473f065e7b9 259 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 172 259 2.0E-25 T 13-09-2016 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386|UniPathway: UPA00619 THL1_RS17910 2ccc18afaef26c0a1fca2473f065e7b9 259 SMART SM00849 12 171 2.3E-36 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS17910 2ccc18afaef26c0a1fca2473f065e7b9 259 Pfam PF00753 Metallo-beta-lactamase superfamily 25 171 2.8E-14 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS17910 2ccc18afaef26c0a1fca2473f065e7b9 259 Gene3D G3DSA:3.60.15.10 5 259 5.4E-88 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS09355 ff7fdf9835c68b825aa3da6163a09bc9 231 SUPERFAMILY SSF54001 50 138 1.96E-10 T 13-09-2016 THL1_RS09355 ff7fdf9835c68b825aa3da6163a09bc9 231 PANTHER PTHR39327:SF1 24 230 2.9E-81 T 13-09-2016 THL1_RS09355 ff7fdf9835c68b825aa3da6163a09bc9 231 Pfam PF06035 Bacterial transglutaminase-like cysteine proteinase BTLCP 75 182 4.0E-18 T 13-09-2016 IPR010319 Transglutaminase-like cysteine peptidase, predicted THL1_RS09355 ff7fdf9835c68b825aa3da6163a09bc9 231 PANTHER PTHR39327 24 230 2.9E-81 T 13-09-2016 THL1_RS26350 159eb5e59b9a5e70a215a44e1d1719f5 70 ProSitePatterns PS01143 Ribosomal protein L31 signature. 35 56 - T 13-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS26350 159eb5e59b9a5e70a215a44e1d1719f5 70 PRINTS PR01249 Ribosomal protein L31 signature 46 64 1.9E-21 T 13-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS26350 159eb5e59b9a5e70a215a44e1d1719f5 70 PRINTS PR01249 Ribosomal protein L31 signature 31 46 1.9E-21 T 13-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS26350 159eb5e59b9a5e70a215a44e1d1719f5 70 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.9E-21 T 13-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS26350 159eb5e59b9a5e70a215a44e1d1719f5 70 Pfam PF01197 Ribosomal protein L31 1 65 6.2E-31 T 13-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS26350 159eb5e59b9a5e70a215a44e1d1719f5 70 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 66 7.6E-34 T 13-09-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS26350 159eb5e59b9a5e70a215a44e1d1719f5 70 PANTHER PTHR33280 1 67 3.6E-36 T 13-09-2016 THL1_RS26350 159eb5e59b9a5e70a215a44e1d1719f5 70 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 68 30.909 T 13-09-2016 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS26350 159eb5e59b9a5e70a215a44e1d1719f5 70 SUPERFAMILY SSF143800 1 67 2.86E-28 T 13-09-2016 THL1_RS22680 5d6651bcbdffef59da95e8ad4fd9bb0e 270 Gene3D G3DSA:3.40.50.720 4 261 2.6E-51 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS22680 5d6651bcbdffef59da95e8ad4fd9bb0e 270 SUPERFAMILY SSF69572 5 252 2.62E-61 T 13-09-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 THL1_RS22680 5d6651bcbdffef59da95e8ad4fd9bb0e 270 PANTHER PTHR10953:SF159 4 159 1.3E-121 T 13-09-2016 THL1_RS22680 5d6651bcbdffef59da95e8ad4fd9bb0e 270 PANTHER PTHR10953:SF159 189 260 1.3E-121 T 13-09-2016 THL1_RS22680 5d6651bcbdffef59da95e8ad4fd9bb0e 270 Pfam PF00899 ThiF family 14 256 3.3E-39 T 13-09-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 THL1_RS22680 5d6651bcbdffef59da95e8ad4fd9bb0e 270 PANTHER PTHR10953 4 159 1.3E-121 T 13-09-2016 THL1_RS22680 5d6651bcbdffef59da95e8ad4fd9bb0e 270 PANTHER PTHR10953 189 260 1.3E-121 T 13-09-2016 THL1_RS03675 2e14dbcf3ceb25bee5d8d81f5f5d72c6 161 PIRSF PIRSF002070 1 159 4.4E-38 T 13-09-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 THL1_RS03675 2e14dbcf3ceb25bee5d8d81f5f5d72c6 161 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 161 8.1E-57 T 13-09-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 THL1_RS03675 2e14dbcf3ceb25bee5d8d81f5f5d72c6 161 PANTHER PTHR10302 1 161 1.1E-50 T 13-09-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 THL1_RS03675 2e14dbcf3ceb25bee5d8d81f5f5d72c6 161 Hamap MF_00984 Single-stranded DNA-binding protein. 5 115 38.16 T 13-09-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 THL1_RS03675 2e14dbcf3ceb25bee5d8d81f5f5d72c6 161 Gene3D G3DSA:2.40.50.140 1 161 3.5E-60 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS03675 2e14dbcf3ceb25bee5d8d81f5f5d72c6 161 SUPERFAMILY SSF50249 3 161 8.23E-60 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS03675 2e14dbcf3ceb25bee5d8d81f5f5d72c6 161 Pfam PF00436 Single-strand binding protein family 5 109 6.2E-41 T 13-09-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 THL1_RS21225 6efc0a19d99faf077cbeb2f67779a5fb 229 Gene3D G3DSA:1.10.3720.10 7 220 5.5E-38 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS21225 6efc0a19d99faf077cbeb2f67779a5fb 229 PANTHER PTHR30133:SF3 1 229 1.8E-139 T 13-09-2016 THL1_RS21225 6efc0a19d99faf077cbeb2f67779a5fb 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 115 6.6E-19 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS21225 6efc0a19d99faf077cbeb2f67779a5fb 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 29 220 2.7E-18 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS21225 6efc0a19d99faf077cbeb2f67779a5fb 229 PANTHER PTHR30133 1 229 1.8E-139 T 13-09-2016 THL1_RS21225 6efc0a19d99faf077cbeb2f67779a5fb 229 SUPERFAMILY SSF161098 7 206 1.03E-37 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS25565 25103f2c2635002b95256eef285cfebf 100 PANTHER PTHR33569 2 99 3.7E-44 T 13-09-2016 THL1_RS25565 25103f2c2635002b95256eef285cfebf 100 PIRSF PIRSF001223 1 100 8.3E-50 T 13-09-2016 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25565 25103f2c2635002b95256eef285cfebf 100 Gene3D G3DSA:3.30.280.10 1 99 8.8E-50 T 13-09-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25565 25103f2c2635002b95256eef285cfebf 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 1.0E-52 T 13-09-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25565 25103f2c2635002b95256eef285cfebf 100 SUPERFAMILY SSF54111 1 99 2.75E-46 T 13-09-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25565 25103f2c2635002b95256eef285cfebf 100 PANTHER PTHR33569:SF1 2 99 3.7E-44 T 13-09-2016 THL1_RS25565 25103f2c2635002b95256eef285cfebf 100 Pfam PF00547 Urease, gamma subunit 1 99 6.0E-47 T 13-09-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25565 25103f2c2635002b95256eef285cfebf 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 34.647 T 13-09-2016 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS25565 25103f2c2635002b95256eef285cfebf 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 4.0E-45 T 13-09-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 THL1_RS21910 f72bf66a0ba6125e61fca6fd1f37d253 492 Pfam PF02646 RmuC family 174 470 2.5E-108 T 13-09-2016 IPR003798 DNA recombination RmuC THL1_RS21910 f72bf66a0ba6125e61fca6fd1f37d253 492 PANTHER PTHR30563 19 488 8.7E-122 T 13-09-2016 THL1_RS13990 1683b315150d52893d070ae4d37cc29c 390 PANTHER PTHR30124 39 383 2.4E-123 T 13-09-2016 THL1_RS13990 1683b315150d52893d070ae4d37cc29c 390 Pfam PF03562 MltA specific insert domain 53 278 1.2E-74 T 13-09-2016 IPR005300 Lytic transglycosylase MltA GO:0004553 THL1_RS13990 1683b315150d52893d070ae4d37cc29c 390 Gene3D G3DSA:2.40.40.10 37 187 1.4E-25 T 13-09-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain THL1_RS13990 1683b315150d52893d070ae4d37cc29c 390 Gene3D G3DSA:2.40.40.10 190 379 1.1E-54 T 13-09-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain THL1_RS13990 1683b315150d52893d070ae4d37cc29c 390 PIRSF PIRSF019422 4 383 1.2E-118 T 13-09-2016 IPR026044 Membrane-bound lytic murein transglycosylase A THL1_RS13990 1683b315150d52893d070ae4d37cc29c 390 PANTHER PTHR30124:SF0 39 383 2.4E-123 T 13-09-2016 THL1_RS13990 1683b315150d52893d070ae4d37cc29c 390 SUPERFAMILY SSF50685 39 379 7.32E-121 T 13-09-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain THL1_RS13990 1683b315150d52893d070ae4d37cc29c 390 Pfam PF06725 3D domain 301 372 2.9E-24 T 13-09-2016 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 THL1_RS13990 1683b315150d52893d070ae4d37cc29c 390 SMART SM00925 124 279 1.5E-81 T 13-09-2016 IPR005300 Lytic transglycosylase MltA GO:0004553 THL1_RS05520 ab51efee82308ba6259d77a313bfd357 287 Pfam PF13751 Transposase DDE domain 160 273 3.0E-15 T 13-09-2016 IPR025668 Transposase DDE domain THL1_RS05520 ab51efee82308ba6259d77a313bfd357 287 Pfam PF05598 Transposase domain (DUF772) 55 115 7.4E-15 T 13-09-2016 IPR008490 Transposase InsH, N-terminal THL1_RS05520 ab51efee82308ba6259d77a313bfd357 287 PANTHER PTHR33408 1 116 4.2E-38 T 13-09-2016 THL1_RS05520 ab51efee82308ba6259d77a313bfd357 287 PANTHER PTHR33408:SF2 1 116 4.2E-38 T 13-09-2016 THL1_RS26470 0c35e6a8aaf461644c77f1e2e3ee25df 244 PIRSF PIRSF039085 1 244 2.9E-107 T 13-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 THL1_RS26470 0c35e6a8aaf461644c77f1e2e3ee25df 244 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS26470 0c35e6a8aaf461644c77f1e2e3ee25df 244 SUPERFAMILY SSF52540 1 239 3.8E-83 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26470 0c35e6a8aaf461644c77f1e2e3ee25df 244 Gene3D G3DSA:3.40.50.300 1 240 5.1E-87 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26470 0c35e6a8aaf461644c77f1e2e3ee25df 244 Pfam PF00005 ABC transporter 21 169 4.5E-39 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS26470 0c35e6a8aaf461644c77f1e2e3ee25df 244 PANTHER PTHR24220:SF327 3 244 7.0E-142 T 13-09-2016 THL1_RS26470 0c35e6a8aaf461644c77f1e2e3ee25df 244 PANTHER PTHR24220 3 244 7.0E-142 T 13-09-2016 THL1_RS26470 0c35e6a8aaf461644c77f1e2e3ee25df 244 SMART SM00382 30 217 4.2E-17 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS28335 445b3fdcdcc28e72ff713f7844df3d15 136 Pfam PF11743 Protein of unknown function (DUF3301) 8 100 1.1E-30 T 13-09-2016 IPR021732 Protein of unknown function DUF3301 THL1_RS01025 2f8cc50e4e19909991df0545920b4e93 332 ProSitePatterns PS00530 Ribonuclease T2 family histidine active site 1. 158 165 - T 13-09-2016 IPR018188 Ribonuclease T2, His active site 1 GO:0003723|GO:0033897 THL1_RS01025 2f8cc50e4e19909991df0545920b4e93 332 Gene3D G3DSA:3.90.730.10 114 300 9.5E-27 T 13-09-2016 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 THL1_RS01025 2f8cc50e4e19909991df0545920b4e93 332 SUPERFAMILY SSF55895 119 301 1.27E-27 T 13-09-2016 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 THL1_RS01025 2f8cc50e4e19909991df0545920b4e93 332 ProSitePatterns PS00531 Ribonuclease T2 family histidine active site 2. 205 216 - T 13-09-2016 IPR033130 Ribonuclease T2, His active site 2 THL1_RS01025 2f8cc50e4e19909991df0545920b4e93 332 Pfam PF00445 Ribonuclease T2 family 123 264 1.1E-12 T 13-09-2016 IPR001568 Ribonuclease T2-like GO:0003723|GO:0033897 THL1_RS16440 a4a3737e517bba4dbc63c044f3e87410 574 SUPERFAMILY SSF52540 196 275 1.5E-14 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16440 a4a3737e517bba4dbc63c044f3e87410 574 SUPERFAMILY SSF52540 366 501 1.5E-14 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16440 a4a3737e517bba4dbc63c044f3e87410 574 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 416 485 9.2E-12 T 13-09-2016 IPR003959 ATPase, AAA-type, core GO:0005524 THL1_RS16440 a4a3737e517bba4dbc63c044f3e87410 574 Gene3D G3DSA:3.40.1140.10 418 498 5.1E-15 T 13-09-2016 THL1_RS16440 a4a3737e517bba4dbc63c044f3e87410 574 Gene3D G3DSA:3.40.1140.10 197 255 5.1E-15 T 13-09-2016 THL1_RS18695 713d4fa5125c58443fa30f092b3fb444 1009 SMART SM00316 37 117 5.9E-13 T 13-09-2016 IPR022967 RNA-binding domain, S1 THL1_RS18695 713d4fa5125c58443fa30f092b3fb444 1009 Pfam PF00575 S1 RNA binding domain 36 116 6.9E-15 T 13-09-2016 IPR003029 S1 domain GO:0003676 THL1_RS18695 713d4fa5125c58443fa30f092b3fb444 1009 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 422 1.0E-166 T 13-09-2016 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 THL1_RS18695 713d4fa5125c58443fa30f092b3fb444 1009 SUPERFAMILY SSF50249 40 123 4.87E-19 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS18695 713d4fa5125c58443fa30f092b3fb444 1009 Gene3D G3DSA:2.40.50.140 31 123 1.8E-34 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS18695 713d4fa5125c58443fa30f092b3fb444 1009 PANTHER PTHR30001 1 831 0.0 T 13-09-2016 THL1_RS18695 713d4fa5125c58443fa30f092b3fb444 1009 Hamap MF_00970 Ribonuclease E [rne]. 1 971 36.495 T 13-09-2016 IPR028878 Ribonuclease E GO:0006396|GO:0008995 THL1_RS18695 713d4fa5125c58443fa30f092b3fb444 1009 Pfam PF10150 Ribonuclease E/G family 119 388 2.4E-96 T 13-09-2016 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 THL1_RS18695 713d4fa5125c58443fa30f092b3fb444 1009 PANTHER PTHR30001:SF1 1 831 0.0 T 13-09-2016 THL1_RS18800 5b9c55a30ced5e965251d607b3875054 521 Gene3D G3DSA:1.10.287.950 274 491 4.2E-62 T 13-09-2016 THL1_RS18800 5b9c55a30ced5e965251d607b3875054 521 SMART SM00283 259 520 2.2E-82 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS18800 5b9c55a30ced5e965251d607b3875054 521 PANTHER PTHR32089 51 521 2.5E-160 T 13-09-2016 THL1_RS18800 5b9c55a30ced5e965251d607b3875054 521 Pfam PF08447 PAS fold 31 112 9.8E-14 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS18800 5b9c55a30ced5e965251d607b3875054 521 SUPERFAMILY SSF55785 21 114 3.49E-25 T 13-09-2016 IPR000014 PAS domain THL1_RS18800 5b9c55a30ced5e965251d607b3875054 521 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 280 309 9.1E-22 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS18800 5b9c55a30ced5e965251d607b3875054 521 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 386 415 9.1E-22 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS18800 5b9c55a30ced5e965251d607b3875054 521 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 357 384 9.1E-22 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS18800 5b9c55a30ced5e965251d607b3875054 521 Gene3D G3DSA:3.30.450.20 20 112 7.9E-22 T 13-09-2016 THL1_RS18800 5b9c55a30ced5e965251d607b3875054 521 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 329 519 9.9E-53 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS18800 5b9c55a30ced5e965251d607b3875054 521 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 109 1.9E-12 T 13-09-2016 IPR000014 PAS domain THL1_RS18800 5b9c55a30ced5e965251d607b3875054 521 PANTHER PTHR32089:SF64 51 521 2.5E-160 T 13-09-2016 THL1_RS18800 5b9c55a30ced5e965251d607b3875054 521 SUPERFAMILY SSF58104 243 521 1.57E-76 T 13-09-2016 THL1_RS18385 a02e8f047259d9d77c9a28a7e7728f0a 291 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 253 6.7E-54 T 13-09-2016 THL1_RS18385 a02e8f047259d9d77c9a28a7e7728f0a 291 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 197 0.0013 T 13-09-2016 THL1_RS18385 a02e8f047259d9d77c9a28a7e7728f0a 291 Gene3D G3DSA:3.40.50.720 4 256 1.5E-72 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18385 a02e8f047259d9d77c9a28a7e7728f0a 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 2.1E-29 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18385 a02e8f047259d9d77c9a28a7e7728f0a 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 2.1E-29 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18385 a02e8f047259d9d77c9a28a7e7728f0a 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 2.1E-29 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18385 a02e8f047259d9d77c9a28a7e7728f0a 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 2.1E-29 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18385 a02e8f047259d9d77c9a28a7e7728f0a 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 2.1E-29 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18385 a02e8f047259d9d77c9a28a7e7728f0a 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 2.1E-29 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS18385 a02e8f047259d9d77c9a28a7e7728f0a 291 PANTHER PTHR24317:SF5 1 291 1.2E-233 T 13-09-2016 THL1_RS18385 a02e8f047259d9d77c9a28a7e7728f0a 291 SUPERFAMILY SSF51735 14 254 3.26E-68 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS18385 a02e8f047259d9d77c9a28a7e7728f0a 291 PANTHER PTHR24317 1 291 1.2E-233 T 13-09-2016 THL1_RS19355 375c87c8ee9b69ac3ad3eb68cdbcb137 726 PANTHER PTHR14226:SF37 128 451 6.7E-99 T 13-09-2016 THL1_RS19355 375c87c8ee9b69ac3ad3eb68cdbcb137 726 Pfam PF01103 Surface antigen 458 723 2.4E-8 T 13-09-2016 IPR000184 Bacterial surface antigen (D15) GO:0019867 THL1_RS19355 375c87c8ee9b69ac3ad3eb68cdbcb137 726 Pfam PF01734 Patatin-like phospholipase 25 217 3.4E-28 T 13-09-2016 IPR002641 Patatin/Phospholipase A2-related GO:0006629 THL1_RS19355 375c87c8ee9b69ac3ad3eb68cdbcb137 726 Gene3D G3DSA:3.40.1090.10 25 232 1.3E-15 T 13-09-2016 THL1_RS19355 375c87c8ee9b69ac3ad3eb68cdbcb137 726 Pfam PF07244 Surface antigen variable number repeat 331 397 2.5E-4 T 13-09-2016 IPR010827 Surface antigen variable number GO:0019867 THL1_RS19355 375c87c8ee9b69ac3ad3eb68cdbcb137 726 SUPERFAMILY SSF52151 123 257 5.23E-59 T 13-09-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THL1_RS19355 375c87c8ee9b69ac3ad3eb68cdbcb137 726 SUPERFAMILY SSF52151 20 92 5.23E-59 T 13-09-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THL1_RS19355 375c87c8ee9b69ac3ad3eb68cdbcb137 726 PANTHER PTHR14226 128 451 6.7E-99 T 13-09-2016 THL1_RS19355 375c87c8ee9b69ac3ad3eb68cdbcb137 726 PANTHER PTHR14226 19 111 6.7E-99 T 13-09-2016 THL1_RS19355 375c87c8ee9b69ac3ad3eb68cdbcb137 726 PANTHER PTHR14226:SF37 19 111 6.7E-99 T 13-09-2016 THL1_RS13930 90f4ebd74e59ee91c07fcaa11972e243 640 Pfam PF06980 Protein of unknown function (DUF1302) 35 640 2.9E-135 T 13-09-2016 IPR010727 Protein of unknown function DUF1302 THL1_RS21920 2de59e31a3dfae5f28cf3ffb3039ea09 160 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 117 159 2.2E-9 T 13-09-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 THL1_RS21920 2de59e31a3dfae5f28cf3ffb3039ea09 160 Gene3D G3DSA:3.10.50.30 83 159 3.3E-13 T 13-09-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 THL1_RS21920 2de59e31a3dfae5f28cf3ffb3039ea09 160 SUPERFAMILY SSF54534 84 159 1.31E-10 T 13-09-2016 THL1_RS21920 2de59e31a3dfae5f28cf3ffb3039ea09 160 PIRSF PIRSF006092 1 160 9.7E-10 T 13-09-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 THL1_RS01175 e5b4167a1a55f7cb12c3cfb8eee618d3 327 PANTHER PTHR10794 5 323 1.3E-71 T 13-09-2016 THL1_RS01175 e5b4167a1a55f7cb12c3cfb8eee618d3 327 PIRSF PIRSF005211 1 327 2.6E-108 T 13-09-2016 IPR012020 AB hydrolase 4 family KEGG: 00051+3.1.1.-|KEGG: 00053+3.1.1.-|KEGG: 00363+3.1.1.-|KEGG: 00365+3.1.1.-|KEGG: 00534+3.1.1.-|KEGG: 00564+3.1.1.-|KEGG: 00623+3.1.1.-|KEGG: 00640+3.1.1.-|KEGG: 00830+3.1.1.-|KEGG: 00900+3.1.1.-|KEGG: 00940+3.1.1.-|KEGG: 00960+3.1.1.- THL1_RS01175 e5b4167a1a55f7cb12c3cfb8eee618d3 327 Pfam PF00561 alpha/beta hydrolase fold 58 306 4.9E-15 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS01175 e5b4167a1a55f7cb12c3cfb8eee618d3 327 Gene3D G3DSA:3.40.50.1820 41 323 9.5E-31 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS01175 e5b4167a1a55f7cb12c3cfb8eee618d3 327 ProSitePatterns PS01133 Uncharacterized protein family UPF0017 signature. 231 272 - T 13-09-2016 IPR000952 AB hydrolase 4, conserved site KEGG: 00051+3.1.1.-|KEGG: 00053+3.1.1.-|KEGG: 00363+3.1.1.-|KEGG: 00365+3.1.1.-|KEGG: 00534+3.1.1.-|KEGG: 00564+3.1.1.-|KEGG: 00623+3.1.1.-|KEGG: 00640+3.1.1.-|KEGG: 00830+3.1.1.-|KEGG: 00900+3.1.1.-|KEGG: 00940+3.1.1.-|KEGG: 00960+3.1.1.- THL1_RS01175 e5b4167a1a55f7cb12c3cfb8eee618d3 327 SUPERFAMILY SSF53474 22 185 4.57E-44 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS01175 e5b4167a1a55f7cb12c3cfb8eee618d3 327 SUPERFAMILY SSF53474 225 323 4.57E-44 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS15345 68606f85a7759edcfc6355e53a9dcb8e 143 PANTHER PTHR30574:SF1 10 136 3.6E-29 T 13-09-2016 THL1_RS15345 68606f85a7759edcfc6355e53a9dcb8e 143 PANTHER PTHR30574 10 136 3.6E-29 T 13-09-2016 THL1_RS27720 9617e47e8f4c3d477504b564f52daa99 465 Pfam PF01554 MatE 18 176 6.9E-24 T 13-09-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 THL1_RS27720 9617e47e8f4c3d477504b564f52daa99 465 Pfam PF01554 MatE 244 410 6.9E-28 T 13-09-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 THL1_RS27720 9617e47e8f4c3d477504b564f52daa99 465 PIRSF PIRSF006603 3 455 2.7E-55 T 13-09-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 THL1_RS27720 9617e47e8f4c3d477504b564f52daa99 465 PANTHER PTHR11206 3 462 5.4E-85 T 13-09-2016 THL1_RS27720 9617e47e8f4c3d477504b564f52daa99 465 PANTHER PTHR11206:SF153 3 462 5.4E-85 T 13-09-2016 THL1_RS27720 9617e47e8f4c3d477504b564f52daa99 465 TIGRFAM TIGR00797 matE: MATE efflux family protein 18 423 4.1E-68 T 13-09-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 THL1_RS14530 06332b225ded21291e6eceb71c90a942 329 PANTHER PTHR11516:SF25 8 329 1.4E-113 T 13-09-2016 THL1_RS14530 06332b225ded21291e6eceb71c90a942 329 SUPERFAMILY SSF52518 5 328 5.18E-85 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS14530 06332b225ded21291e6eceb71c90a942 329 PANTHER PTHR11516 8 329 1.4E-113 T 13-09-2016 THL1_RS14530 06332b225ded21291e6eceb71c90a942 329 Gene3D G3DSA:3.40.50.970 4 328 1.4E-108 T 13-09-2016 IPR029061 Thiamin diphosphate-binding fold THL1_RS14530 06332b225ded21291e6eceb71c90a942 329 Pfam PF00676 Dehydrogenase E1 component 45 320 8.7E-70 T 13-09-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 THL1_RS22165 21165fc01092c8b0677090207db1ff42 68 Pfam PF04102 SlyX 3 68 2.6E-24 T 13-09-2016 IPR007236 SlyX THL1_RS22165 21165fc01092c8b0677090207db1ff42 68 Gene3D G3DSA:1.20.5.300 2 47 7.3E-19 T 13-09-2016 THL1_RS22165 21165fc01092c8b0677090207db1ff42 68 PANTHER PTHR36508 1 68 8.7E-22 T 13-09-2016 THL1_RS22165 21165fc01092c8b0677090207db1ff42 68 Hamap MF_00715 Protein SlyX [slyX]. 2 68 16.776 T 13-09-2016 IPR007236 SlyX THL1_RS17190 fd15bd43c08d378b0c5450f637b37499 377 PANTHER PTHR12286 2 131 1.4E-16 T 13-09-2016 THL1_RS17190 fd15bd43c08d378b0c5450f637b37499 377 SUPERFAMILY SSF51735 1 105 2.92E-11 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS17190 fd15bd43c08d378b0c5450f637b37499 377 Gene3D G3DSA:3.40.50.720 6 122 1.6E-11 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS17190 fd15bd43c08d378b0c5450f637b37499 377 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 6 121 3.7E-9 T 13-09-2016 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 THL1_RS12700 8ab42e84828986a5ce0ed891c91c2daf 285 Gene3D G3DSA:3.40.50.720 117 280 1.3E-42 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS12700 8ab42e84828986a5ce0ed891c91c2daf 285 PANTHER PTHR21089 1 276 1.3E-57 T 13-09-2016 THL1_RS12700 8ab42e84828986a5ce0ed891c91c2daf 285 Gene3D G3DSA:3.40.192.10 5 116 5.3E-33 T 13-09-2016 THL1_RS12700 8ab42e84828986a5ce0ed891c91c2daf 285 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 12 99 3.4E-21 T 13-09-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 THL1_RS12700 8ab42e84828986a5ce0ed891c91c2daf 285 SUPERFAMILY SSF53223 7 111 7.48E-27 T 13-09-2016 THL1_RS12700 8ab42e84828986a5ce0ed891c91c2daf 285 PANTHER PTHR21089:SF1 1 276 1.3E-57 T 13-09-2016 THL1_RS12700 8ab42e84828986a5ce0ed891c91c2daf 285 SUPERFAMILY SSF51735 112 281 1.62E-36 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS03670 e5fd6ca2a8929607b7112a2ccb961375 464 SUPERFAMILY SSF103473 15 396 4.71E-63 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS03670 e5fd6ca2a8929607b7112a2ccb961375 464 Gene3D G3DSA:1.20.1250.20 221 396 1.7E-21 T 13-09-2016 THL1_RS03670 e5fd6ca2a8929607b7112a2ccb961375 464 Gene3D G3DSA:1.20.1250.20 20 195 6.0E-34 T 13-09-2016 THL1_RS03670 e5fd6ca2a8929607b7112a2ccb961375 464 PANTHER PTHR23510 13 404 1.4E-217 T 13-09-2016 THL1_RS03670 e5fd6ca2a8929607b7112a2ccb961375 464 PANTHER PTHR23510:SF6 13 404 1.4E-217 T 13-09-2016 THL1_RS03670 e5fd6ca2a8929607b7112a2ccb961375 464 Pfam PF07690 Major Facilitator Superfamily 20 358 4.6E-41 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS08770 ecb1d4291a6de580f22cf7133c2aaa30 104 SUPERFAMILY SSF54909 1 94 5.37E-27 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS08770 ecb1d4291a6de580f22cf7133c2aaa30 104 PANTHER PTHR33336 1 95 5.1E-21 T 13-09-2016 THL1_RS08770 ecb1d4291a6de580f22cf7133c2aaa30 104 Pfam PF03992 Antibiotic biosynthesis monooxygenase 12 79 2.8E-19 T 13-09-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain THL1_RS08770 ecb1d4291a6de580f22cf7133c2aaa30 104 Gene3D G3DSA:3.30.70.900 8 99 5.3E-28 T 13-09-2016 THL1_RS01145 b66744137b1933d3d9a596bd36747527 83 SUPERFAMILY SSF54862 5 73 1.55E-19 T 13-09-2016 THL1_RS01145 b66744137b1933d3d9a596bd36747527 83 Gene3D G3DSA:3.30.70.20 6 75 9.8E-19 T 13-09-2016 THL1_RS01145 b66744137b1933d3d9a596bd36747527 83 PANTHER PTHR24960:SF38 1 76 1.2E-28 T 13-09-2016 THL1_RS01145 b66744137b1933d3d9a596bd36747527 83 Pfam PF00037 4Fe-4S binding domain 5 25 3.2E-6 T 13-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THL1_RS01145 b66744137b1933d3d9a596bd36747527 83 PANTHER PTHR24960 1 76 1.2E-28 T 13-09-2016 THL1_RS01145 b66744137b1933d3d9a596bd36747527 83 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS03765 deb86bfda546e6f23a210ec01dcfb527 236 TIGRFAM TIGR02458 CbtA: cobalt transporter subunit CbtA (proposed) 1 230 9.1E-91 T 13-09-2016 IPR012666 Cobalt transporter subunit CbtA, putative THL1_RS03765 deb86bfda546e6f23a210ec01dcfb527 236 Pfam PF09490 Probable cobalt transporter subunit (CbtA) 2 229 3.7E-67 T 13-09-2016 IPR012666 Cobalt transporter subunit CbtA, putative THL1_RS13000 a5650d4457f5e8678c450c86a6b35cac 633 PANTHER PTHR30540:SF7 27 564 1.3E-235 T 13-09-2016 THL1_RS13000 a5650d4457f5e8678c450c86a6b35cac 633 PANTHER PTHR30540 27 564 1.3E-235 T 13-09-2016 THL1_RS13000 a5650d4457f5e8678c450c86a6b35cac 633 Pfam PF02705 K+ potassium transporter 23 555 8.1E-205 T 13-09-2016 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 THL1_RS13000 a5650d4457f5e8678c450c86a6b35cac 633 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 14 633 34.045 T 13-09-2016 IPR023051 Potassium uptake protein, low affinity, Kup THL1_RS03970 fa787cc239cbb79b82097f92db1301e7 206 Gene3D G3DSA:2.40.360.10 6 202 1.9E-41 T 13-09-2016 IPR023373 YmcC-like domain THL1_RS03970 fa787cc239cbb79b82097f92db1301e7 206 Pfam PF11102 Group 4 capsule polysaccharide lipoprotein gfcB, YjbF 3 192 9.9E-42 T 13-09-2016 IPR021308 Group 4 capsule polysaccharide formation lipoprotein GfcB THL1_RS03970 fa787cc239cbb79b82097f92db1301e7 206 SUPERFAMILY SSF159270 12 200 6.54E-42 T 13-09-2016 IPR023373 YmcC-like domain THL1_RS12900 d8c18a60463ba151cc2a3e2644a8e6fb 225 PANTHER PTHR11403:SF8 10 225 1.2E-85 T 13-09-2016 THL1_RS12900 d8c18a60463ba151cc2a3e2644a8e6fb 225 Gene3D G3DSA:1.20.120.80 31 225 4.7E-51 T 13-09-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 THL1_RS12900 d8c18a60463ba151cc2a3e2644a8e6fb 225 SUPERFAMILY SSF81452 12 225 1.24E-50 T 13-09-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 THL1_RS12900 d8c18a60463ba151cc2a3e2644a8e6fb 225 PANTHER PTHR11403 10 225 1.2E-85 T 13-09-2016 IPR024791 Cytochrome c oxidase subunit III GO:0015002|GO:0016020|GO:0019646 THL1_RS12900 d8c18a60463ba151cc2a3e2644a8e6fb 225 Pfam PF00510 Cytochrome c oxidase subunit III 36 225 9.4E-22 T 13-09-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 THL1_RS10045 7915630c6b68c574174c7d8e5f87d131 966 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 201 272 1.3E-27 T 13-09-2016 IPR020012 Motility protein FimV, N-terminal THL1_RS10045 7915630c6b68c574174c7d8e5f87d131 966 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 922 965 5.7E-21 T 13-09-2016 IPR020011 Motility protein FimV, C-terminal THL1_RS10045 7915630c6b68c574174c7d8e5f87d131 966 Gene3D G3DSA:1.25.40.10 592 635 8.7E-5 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS10045 7915630c6b68c574174c7d8e5f87d131 966 Gene3D G3DSA:1.25.40.10 922 951 8.7E-5 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS10045 7915630c6b68c574174c7d8e5f87d131 966 SUPERFAMILY SSF48452 590 640 3.08E-5 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS04645 0bfd59a416fbd7d306ef8bed6c1b2dd3 323 PANTHER PTHR30388 5 317 6.9E-95 T 13-09-2016 THL1_RS04645 0bfd59a416fbd7d306ef8bed6c1b2dd3 323 Pfam PF02625 XdhC and CoxI family 15 69 2.7E-16 T 13-09-2016 IPR003777 XdhC- CoxI THL1_RS04645 0bfd59a416fbd7d306ef8bed6c1b2dd3 323 Pfam PF13478 XdhC Rossmann domain 169 311 6.5E-34 T 13-09-2016 IPR027051 XdhC Rossmann domain THL1_RS04645 0bfd59a416fbd7d306ef8bed6c1b2dd3 323 PANTHER PTHR30388:SF4 5 317 6.9E-95 T 13-09-2016 THL1_RS26395 cab4add2ac72a34fdb07a4ec4005bbf4 560 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 75 243 3.2E-66 T 13-09-2016 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.- THL1_RS26395 cab4add2ac72a34fdb07a4ec4005bbf4 560 TIGRFAM TIGR01839 PHA_synth_II: poly(R)-hydroxyalkanoic acid synthase, class II 1 560 0.0 T 13-09-2016 IPR011287 Poly(R)-hydroxyalkanoic acid synthase, class II GO:0016746|GO:0042619 KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.- THL1_RS26395 cab4add2ac72a34fdb07a4ec4005bbf4 560 PANTHER PTHR36837:SF2 1 560 3.7E-268 T 13-09-2016 THL1_RS26395 cab4add2ac72a34fdb07a4ec4005bbf4 560 PANTHER PTHR36837 1 560 3.7E-268 T 13-09-2016 THL1_RS26395 cab4add2ac72a34fdb07a4ec4005bbf4 560 SUPERFAMILY SSF53474 201 489 3.56E-32 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS26395 cab4add2ac72a34fdb07a4ec4005bbf4 560 Gene3D G3DSA:3.40.50.1820 161 531 3.7E-59 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS15735 641691ab258b1c24d2dd433f5fd83358 117 SUPERFAMILY SSF54909 1 116 3.32E-53 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS15735 641691ab258b1c24d2dd433f5fd83358 117 PIRSF PIRSF007028 1 117 2.7E-50 T 13-09-2016 IPR009874 Protein of unknown function DUF1428 THL1_RS15735 641691ab258b1c24d2dd433f5fd83358 117 Gene3D G3DSA:3.30.70.900 1 116 1.0E-56 T 13-09-2016 THL1_RS15735 641691ab258b1c24d2dd433f5fd83358 117 Pfam PF07237 Protein of unknown function (DUF1428) 2 103 1.1E-47 T 13-09-2016 IPR009874 Protein of unknown function DUF1428 THL1_RS06040 10abefed08969eabbb657c3ac5b6c68e 459 Pfam PF02601 Exonuclease VII, large subunit 132 443 3.9E-100 T 13-09-2016 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 THL1_RS06040 10abefed08969eabbb657c3ac5b6c68e 459 PANTHER PTHR30008:SF0 8 458 5.2E-180 T 13-09-2016 THL1_RS06040 10abefed08969eabbb657c3ac5b6c68e 459 Gene3D G3DSA:2.40.50.140 36 113 5.5E-5 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS06040 10abefed08969eabbb657c3ac5b6c68e 459 PANTHER PTHR30008 8 458 5.2E-180 T 13-09-2016 THL1_RS06040 10abefed08969eabbb657c3ac5b6c68e 459 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 17 360 4.3E-134 T 13-09-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 THL1_RS06040 10abefed08969eabbb657c3ac5b6c68e 459 Pfam PF13742 OB-fold nucleic acid binding domain 16 108 4.7E-31 T 13-09-2016 IPR025824 OB-fold nucleic acid binding domain GO:0003676 THL1_RS06040 10abefed08969eabbb657c3ac5b6c68e 459 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 13 446 31.77 T 13-09-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 THL1_RS01155 19b654340804c7ce8e4dc92811990128 531 PANTHER PTHR11552:SF92 7 530 2.9E-163 T 13-09-2016 THL1_RS01155 19b654340804c7ce8e4dc92811990128 531 SUPERFAMILY SSF51905 465 528 3.02E-57 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01155 19b654340804c7ce8e4dc92811990128 531 SUPERFAMILY SSF51905 18 297 3.02E-57 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01155 19b654340804c7ce8e4dc92811990128 531 Pfam PF00732 GMC oxidoreductase 33 285 4.8E-52 T 13-09-2016 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 THL1_RS01155 19b654340804c7ce8e4dc92811990128 531 Gene3D G3DSA:3.50.50.60 459 527 2.2E-71 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01155 19b654340804c7ce8e4dc92811990128 531 Gene3D G3DSA:3.50.50.60 399 412 2.2E-71 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01155 19b654340804c7ce8e4dc92811990128 531 Gene3D G3DSA:3.50.50.60 30 148 2.2E-71 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01155 19b654340804c7ce8e4dc92811990128 531 Gene3D G3DSA:3.50.50.60 193 297 2.2E-71 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS01155 19b654340804c7ce8e4dc92811990128 531 PANTHER PTHR11552 7 530 2.9E-163 T 13-09-2016 THL1_RS01155 19b654340804c7ce8e4dc92811990128 531 Pfam PF05199 GMC oxidoreductase 384 519 7.2E-23 T 13-09-2016 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 THL1_RS05075 b774d012366f2c2c1433fe32c3e92753 405 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 166 194 - T 13-09-2016 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 THL1_RS05075 b774d012366f2c2c1433fe32c3e92753 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 386 405 2.2E-19 T 13-09-2016 IPR003004 GspF/PilC family THL1_RS05075 b774d012366f2c2c1433fe32c3e92753 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 67 79 2.2E-19 T 13-09-2016 IPR003004 GspF/PilC family THL1_RS05075 b774d012366f2c2c1433fe32c3e92753 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 166 194 2.2E-19 T 13-09-2016 IPR003004 GspF/PilC family THL1_RS05075 b774d012366f2c2c1433fe32c3e92753 405 PRINTS PR00812 Bacterial general secretion pathway protein F signature 370 384 2.2E-19 T 13-09-2016 IPR003004 GspF/PilC family THL1_RS05075 b774d012366f2c2c1433fe32c3e92753 405 PANTHER PTHR30012:SF0 9 405 6.8E-160 T 13-09-2016 THL1_RS05075 b774d012366f2c2c1433fe32c3e92753 405 Pfam PF00482 Type II secretion system (T2SS), protein F 275 397 2.7E-30 T 13-09-2016 IPR018076 Type II secretion system F domain THL1_RS05075 b774d012366f2c2c1433fe32c3e92753 405 Pfam PF00482 Type II secretion system (T2SS), protein F 71 194 1.4E-30 T 13-09-2016 IPR018076 Type II secretion system F domain THL1_RS05075 b774d012366f2c2c1433fe32c3e92753 405 PANTHER PTHR30012 9 405 6.8E-160 T 13-09-2016 THL1_RS20430 2e73139ff92b610c4ab1975ca328f737 247 PANTHER PTHR17630 4 247 1.2E-65 T 13-09-2016 THL1_RS20430 2e73139ff92b610c4ab1975ca328f737 247 PANTHER PTHR17630:SF51 4 247 1.2E-65 T 13-09-2016 THL1_RS20430 2e73139ff92b610c4ab1975ca328f737 247 Pfam PF01738 Dienelactone hydrolase family 16 243 1.0E-43 T 13-09-2016 IPR002925 Dienelactone hydrolase GO:0016787 THL1_RS20430 2e73139ff92b610c4ab1975ca328f737 247 SUPERFAMILY SSF53474 3 245 3.77E-46 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS20430 2e73139ff92b610c4ab1975ca328f737 247 Gene3D G3DSA:3.40.50.1820 2 243 2.1E-53 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS23595 fea26b6530eed053600393779be67f6b 189 PANTHER PTHR40057:SF1 1 174 3.9E-55 T 13-09-2016 THL1_RS23595 fea26b6530eed053600393779be67f6b 189 SUPERFAMILY SSF54909 3 100 3.71E-18 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS23595 fea26b6530eed053600393779be67f6b 189 Gene3D G3DSA:3.30.70.900 6 92 6.3E-13 T 13-09-2016 THL1_RS23595 fea26b6530eed053600393779be67f6b 189 PANTHER PTHR40057 1 174 3.9E-55 T 13-09-2016 THL1_RS03335 79305a2d350ca17a787f66196bfdcc14 215 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 53 213 8.7E-40 T 13-09-2016 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 UniPathway: UPA00232 THL1_RS03335 79305a2d350ca17a787f66196bfdcc14 215 PANTHER PTHR11237 1 215 6.4E-127 T 13-09-2016 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 UniPathway: UPA00232 THL1_RS03335 79305a2d350ca17a787f66196bfdcc14 215 PANTHER PTHR11237:SF3 1 215 6.4E-127 T 13-09-2016 THL1_RS03335 79305a2d350ca17a787f66196bfdcc14 215 SUPERFAMILY SSF47240 51 184 1.68E-18 T 13-09-2016 IPR009078 Ferritin-like superfamily THL1_RS03335 79305a2d350ca17a787f66196bfdcc14 215 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 14 215 30.899 T 13-09-2016 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 UniPathway: UPA00232 THL1_RS03335 79305a2d350ca17a787f66196bfdcc14 215 Gene3D G3DSA:1.20.1260.10 45 183 1.0E-13 T 13-09-2016 IPR012347 Ferritin-related THL1_RS12825 bc12512a31d8d7535cfdd4162a2086f5 255 PANTHER PTHR35272:SF2 1 255 2.7E-105 T 13-09-2016 THL1_RS12825 bc12512a31d8d7535cfdd4162a2086f5 255 SUPERFAMILY SSF54423 27 85 3.14E-19 T 13-09-2016 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal THL1_RS12825 bc12512a31d8d7535cfdd4162a2086f5 255 Gene3D G3DSA:3.40.30.10 112 253 1.1E-30 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS12825 bc12512a31d8d7535cfdd4162a2086f5 255 Gene3D G3DSA:3.10.450.70 59 85 1.4E-4 T 13-09-2016 IPR009094 Disulphide bond isomerase, DsbC, N-terminal THL1_RS12825 bc12512a31d8d7535cfdd4162a2086f5 255 SUPERFAMILY SSF52833 95 252 9.31E-32 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS12825 bc12512a31d8d7535cfdd4162a2086f5 255 PANTHER PTHR35272 1 255 2.7E-105 T 13-09-2016 THL1_RS12825 bc12512a31d8d7535cfdd4162a2086f5 255 Pfam PF13098 Thioredoxin-like domain 119 249 7.2E-13 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS20535 23631320006798842a05aa4cdb9b7911 544 Pfam PF00501 AMP-binding enzyme 23 447 3.2E-80 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS20535 23631320006798842a05aa4cdb9b7911 544 Gene3D G3DSA:3.30.300.30 444 542 1.3E-25 T 13-09-2016 THL1_RS20535 23631320006798842a05aa4cdb9b7911 544 Gene3D G3DSA:2.30.38.10 364 437 7.1E-24 T 13-09-2016 THL1_RS20535 23631320006798842a05aa4cdb9b7911 544 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 522 5.3E-15 T 13-09-2016 IPR025110 AMP-binding enzyme C-terminal domain THL1_RS20535 23631320006798842a05aa4cdb9b7911 544 Gene3D G3DSA:3.40.50.980 207 357 2.0E-27 T 13-09-2016 THL1_RS20535 23631320006798842a05aa4cdb9b7911 544 PANTHER PTHR24095 185 542 9.3E-115 T 13-09-2016 THL1_RS20535 23631320006798842a05aa4cdb9b7911 544 PANTHER PTHR24095 13 164 9.3E-115 T 13-09-2016 THL1_RS20535 23631320006798842a05aa4cdb9b7911 544 Gene3D G3DSA:3.40.50.980 13 131 5.1E-36 T 13-09-2016 THL1_RS20535 23631320006798842a05aa4cdb9b7911 544 Gene3D G3DSA:3.40.50.980 172 206 5.1E-36 T 13-09-2016 THL1_RS20535 23631320006798842a05aa4cdb9b7911 544 SUPERFAMILY SSF56801 11 543 6.41E-125 T 13-09-2016 THL1_RS07815 ceb70b409277ed93dd64bc2e829b7993 271 SMART SM00382 50 241 1.6E-11 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS07815 ceb70b409277ed93dd64bc2e829b7993 271 PANTHER PTHR24220 26 268 8.2E-107 T 13-09-2016 THL1_RS07815 ceb70b409277ed93dd64bc2e829b7993 271 Pfam PF00005 ABC transporter 42 193 2.7E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS07815 ceb70b409277ed93dd64bc2e829b7993 271 SUPERFAMILY SSF52540 25 263 3.84E-71 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07815 ceb70b409277ed93dd64bc2e829b7993 271 PANTHER PTHR24220:SF474 26 268 8.2E-107 T 13-09-2016 THL1_RS07815 ceb70b409277ed93dd64bc2e829b7993 271 Gene3D G3DSA:3.40.50.300 24 265 1.9E-78 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07815 ceb70b409277ed93dd64bc2e829b7993 271 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS07815 ceb70b409277ed93dd64bc2e829b7993 271 PIRSF PIRSF039085 21 269 3.5E-93 T 13-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 THL1_RS15900 705c3f293f905590b01f12f46afabcc0 301 Gene3D G3DSA:3.20.20.70 5 291 8.7E-90 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS15900 705c3f293f905590b01f12f46afabcc0 301 Pfam PF00682 HMGL-like 6 278 1.5E-54 T 13-09-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 THL1_RS15900 705c3f293f905590b01f12f46afabcc0 301 ProSitePatterns PS01062 Hydroxymethylglutaryl-coenzyme A lyase active site. 233 242 - T 13-09-2016 IPR000138 Hydroxymethylglutaryl-CoA lyase, active site GO:0004419 KEGG: 00072+4.1.3.4|KEGG: 00280+4.1.3.4|KEGG: 00281+4.1.3.4|KEGG: 00650+4.1.3.4|MetaCyc: PWY-5074|UniPathway: UPA00896 THL1_RS15900 705c3f293f905590b01f12f46afabcc0 301 PANTHER PTHR10277:SF40 2 296 6.4E-178 T 13-09-2016 THL1_RS15900 705c3f293f905590b01f12f46afabcc0 301 SUPERFAMILY SSF51569 1 292 1.14E-72 T 13-09-2016 THL1_RS15900 705c3f293f905590b01f12f46afabcc0 301 PANTHER PTHR10277 2 296 6.4E-178 T 13-09-2016 THL1_RS26530 b49f52dd83cc8bc20056b66bb7f0805b 322 PANTHER PTHR30177 6 305 1.4E-184 T 13-09-2016 THL1_RS26530 b49f52dd83cc8bc20056b66bb7f0805b 322 Gene3D G3DSA:3.40.190.100 116 253 3.1E-41 T 13-09-2016 THL1_RS26530 b49f52dd83cc8bc20056b66bb7f0805b 322 SUPERFAMILY SSF53850 28 317 9.77E-74 T 13-09-2016 THL1_RS26530 b49f52dd83cc8bc20056b66bb7f0805b 322 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 33 301 5.8E-68 T 13-09-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 THL1_RS26530 b49f52dd83cc8bc20056b66bb7f0805b 322 PANTHER PTHR30177:SF14 6 305 1.4E-184 T 13-09-2016 THL1_RS26530 b49f52dd83cc8bc20056b66bb7f0805b 322 Gene3D G3DSA:3.40.190.10 30 115 1.4E-20 T 13-09-2016 THL1_RS26530 b49f52dd83cc8bc20056b66bb7f0805b 322 Gene3D G3DSA:3.40.190.10 254 312 1.4E-20 T 13-09-2016 THL1_RS19080 138c39dc4da925ca917491a3330277ef 350 Pfam PF13416 Bacterial extracellular solute-binding protein 60 308 3.9E-38 T 13-09-2016 THL1_RS19080 138c39dc4da925ca917491a3330277ef 350 Gene3D G3DSA:3.40.190.10 132 290 2.5E-35 T 13-09-2016 THL1_RS19080 138c39dc4da925ca917491a3330277ef 350 PANTHER PTHR30222 15 350 1.5E-149 T 13-09-2016 THL1_RS19080 138c39dc4da925ca917491a3330277ef 350 PANTHER PTHR30222:SF2 15 350 1.5E-149 T 13-09-2016 THL1_RS19080 138c39dc4da925ca917491a3330277ef 350 SUPERFAMILY SSF53850 31 347 4.02E-61 T 13-09-2016 THL1_RS05565 63901e077c31e5968e2601662dd0434d 176 SMART SM00749 39 100 1.5 T 13-09-2016 IPR014004 Transport-associated and nodulation domain, bacteria THL1_RS05565 63901e077c31e5968e2601662dd0434d 176 SMART SM00749 114 175 0.11 T 13-09-2016 IPR014004 Transport-associated and nodulation domain, bacteria THL1_RS05565 63901e077c31e5968e2601662dd0434d 176 PANTHER PTHR34606 23 176 1.5E-56 T 13-09-2016 THL1_RS05565 63901e077c31e5968e2601662dd0434d 176 Pfam PF04972 BON domain 109 174 1.0E-14 T 13-09-2016 IPR007055 BON domain THL1_RS05565 63901e077c31e5968e2601662dd0434d 176 Pfam PF04972 BON domain 31 99 7.8E-13 T 13-09-2016 IPR007055 BON domain THL1_RS05565 63901e077c31e5968e2601662dd0434d 176 PANTHER PTHR34606:SF4 23 176 1.5E-56 T 13-09-2016 THL1_RS08230 4eaaafc728eec03c3af44189b3bbe67a 89 PIRSF PIRSF028784 1 89 4.7E-31 T 13-09-2016 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 THL1_RS08230 4eaaafc728eec03c3af44189b3bbe67a 89 PANTHER PTHR34702:SF1 1 89 3.9E-22 T 13-09-2016 THL1_RS08230 4eaaafc728eec03c3af44189b3bbe67a 89 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 82 4.5E-23 T 13-09-2016 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 THL1_RS08230 4eaaafc728eec03c3af44189b3bbe67a 89 PANTHER PTHR34702 1 89 3.9E-22 T 13-09-2016 THL1_RS13220 6d90d19c8fc8b63722d532c003564fe9 411 SUPERFAMILY SSF51395 2 347 2.12E-96 T 13-09-2016 THL1_RS13220 6d90d19c8fc8b63722d532c003564fe9 411 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 344 2.2E-52 T 13-09-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 THL1_RS13220 6d90d19c8fc8b63722d532c003564fe9 411 PANTHER PTHR22893:SF6 1 343 8.0E-141 T 13-09-2016 THL1_RS13220 6d90d19c8fc8b63722d532c003564fe9 411 PANTHER PTHR22893 1 343 8.0E-141 T 13-09-2016 THL1_RS13220 6d90d19c8fc8b63722d532c003564fe9 411 Gene3D G3DSA:3.20.20.70 1 347 3.1E-105 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS22040 c52ff21d83a651c621a283513194cdf2 185 Pfam PF13740 ACT domain 9 82 4.9E-15 T 13-09-2016 THL1_RS22040 c52ff21d83a651c621a283513194cdf2 185 PANTHER PTHR34875 1 184 3.2E-52 T 13-09-2016 THL1_RS22040 c52ff21d83a651c621a283513194cdf2 185 Gene3D G3DSA:3.30.70.260 98 183 4.1E-14 T 13-09-2016 THL1_RS22040 c52ff21d83a651c621a283513194cdf2 185 Gene3D G3DSA:3.30.70.260 8 87 5.6E-13 T 13-09-2016 THL1_RS22040 c52ff21d83a651c621a283513194cdf2 185 PANTHER PTHR34875:SF3 1 184 3.2E-52 T 13-09-2016 THL1_RS22040 c52ff21d83a651c621a283513194cdf2 185 PIRSF PIRSF028103 7 182 8.6E-58 T 13-09-2016 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 THL1_RS22040 c52ff21d83a651c621a283513194cdf2 185 SUPERFAMILY SSF55021 7 89 9.61E-9 T 13-09-2016 THL1_RS22040 c52ff21d83a651c621a283513194cdf2 185 SUPERFAMILY SSF55021 94 181 2.14E-14 T 13-09-2016 THL1_RS00545 d1207546b7d4c4535a2d5c3c851f8e62 302 Gene3D G3DSA:1.10.10.10 2 82 8.4E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00545 d1207546b7d4c4535a2d5c3c851f8e62 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.7E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS00545 d1207546b7d4c4535a2d5c3c851f8e62 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.7E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS00545 d1207546b7d4c4535a2d5c3c851f8e62 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.7E-8 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS00545 d1207546b7d4c4535a2d5c3c851f8e62 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 66 8.9E-18 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS00545 d1207546b7d4c4535a2d5c3c851f8e62 302 SUPERFAMILY SSF53850 95 296 5.61E-34 T 13-09-2016 THL1_RS00545 d1207546b7d4c4535a2d5c3c851f8e62 302 Pfam PF03466 LysR substrate binding domain 90 292 2.4E-33 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS00545 d1207546b7d4c4535a2d5c3c851f8e62 302 Gene3D G3DSA:3.40.190.10 95 177 2.5E-6 T 13-09-2016 THL1_RS00545 d1207546b7d4c4535a2d5c3c851f8e62 302 PANTHER PTHR30537 1 298 6.4E-143 T 13-09-2016 THL1_RS00545 d1207546b7d4c4535a2d5c3c851f8e62 302 SUPERFAMILY SSF46785 4 81 8.74E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS00545 d1207546b7d4c4535a2d5c3c851f8e62 302 PANTHER PTHR30537:SF15 1 298 6.4E-143 T 13-09-2016 THL1_RS00545 d1207546b7d4c4535a2d5c3c851f8e62 302 Gene3D G3DSA:3.40.190.10 178 262 1.4E-34 T 13-09-2016 THL1_RS17335 8d4a1bd9c20dff069bc7717b93e0fd86 426 Pfam PF03743 Bacterial conjugation TrbI-like protein 232 412 1.5E-56 T 13-09-2016 IPR005498 Type IV secretion system, VirB10 / TraB / TrbI THL1_RS11760 35ae58b0653e2b01bb080f0c12c41ce0 834 Pfam PF02687 FtsX-like permease family 714 826 2.8E-7 T 13-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 THL1_RS11760 35ae58b0653e2b01bb080f0c12c41ce0 834 PANTHER PTHR30287 8 834 4.2E-146 T 13-09-2016 THL1_RS26315 1523c25604c3e82908f5dd9b9c8afea3 204 PANTHER PTHR40278 1 195 6.3E-60 T 13-09-2016 THL1_RS26315 1523c25604c3e82908f5dd9b9c8afea3 204 Pfam PF05137 Fimbrial assembly protein (PilN) 100 177 7.3E-21 T 13-09-2016 IPR007813 Fimbrial assembly PilN THL1_RS26315 1523c25604c3e82908f5dd9b9c8afea3 204 PANTHER PTHR40278:SF1 1 195 6.3E-60 T 13-09-2016 THL1_RS26045 42cbc2a8b0c6c880c755be1b37a2f829 391 Gene3D G3DSA:3.50.50.60 5 223 3.8E-18 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS26045 42cbc2a8b0c6c880c755be1b37a2f829 391 SUPERFAMILY SSF51905 7 222 1.3E-19 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS26045 42cbc2a8b0c6c880c755be1b37a2f829 391 SUPERFAMILY SSF51905 250 304 1.3E-19 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS26045 42cbc2a8b0c6c880c755be1b37a2f829 391 Pfam PF01266 FAD dependent oxidoreductase 8 314 4.3E-17 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS22510 a08659988e2bd23326738dfbfd8f5300 157 Pfam PF02542 YgbB family 1 154 1.8E-67 T 13-09-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS22510 a08659988e2bd23326738dfbfd8f5300 157 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 156 36.425 T 13-09-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS22510 a08659988e2bd23326738dfbfd8f5300 157 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 155 7.8E-72 T 13-09-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS22510 a08659988e2bd23326738dfbfd8f5300 157 SUPERFAMILY SSF69765 1 155 9.29E-67 T 13-09-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS22510 a08659988e2bd23326738dfbfd8f5300 157 PANTHER PTHR32125 1 155 5.2E-60 T 13-09-2016 THL1_RS22510 a08659988e2bd23326738dfbfd8f5300 157 Gene3D G3DSA:3.30.1330.50 1 155 1.4E-72 T 13-09-2016 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS22510 a08659988e2bd23326738dfbfd8f5300 157 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 13-09-2016 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560|UniPathway: UPA00056 THL1_RS11555 4478081ec400cd86a6e6fd4d04a993ff 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 262 4.8E-40 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS11555 4478081ec400cd86a6e6fd4d04a993ff 263 SUPERFAMILY SSF52096 7 263 1.18E-60 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS11555 4478081ec400cd86a6e6fd4d04a993ff 263 Gene3D G3DSA:3.90.226.10 8 256 2.5E-58 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS11555 4478081ec400cd86a6e6fd4d04a993ff 263 PANTHER PTHR11941:SF82 1 260 5.6E-154 T 13-09-2016 THL1_RS11555 4478081ec400cd86a6e6fd4d04a993ff 263 PANTHER PTHR11941 1 260 5.6E-154 T 13-09-2016 THL1_RS05005 21faae050213388a896fbcf76e5178df 778 Pfam PF07793 Protein of unknown function (DUF1631) 23 770 1.4E-225 T 13-09-2016 IPR012434 Protein of unknown function DUF1631 THL1_RS01115 bacc5f941dff67c011f6ea2ca4fde94f 398 SUPERFAMILY SSF53335 85 391 7.37E-73 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS01115 bacc5f941dff67c011f6ea2ca4fde94f 398 Gene3D G3DSA:2.30.130.10 5 74 1.8E-11 T 13-09-2016 IPR015947 PUA-like domain THL1_RS01115 bacc5f941dff67c011f6ea2ca4fde94f 398 Gene3D G3DSA:3.40.50.150 185 393 2.0E-61 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS01115 bacc5f941dff67c011f6ea2ca4fde94f 398 Gene3D G3DSA:3.30.750.80 78 180 1.4E-31 T 13-09-2016 THL1_RS01115 bacc5f941dff67c011f6ea2ca4fde94f 398 SUPERFAMILY SSF88697 4 74 3.48E-9 T 13-09-2016 IPR015947 PUA-like domain THL1_RS01115 bacc5f941dff67c011f6ea2ca4fde94f 398 PANTHER PTHR11061 3 398 4.6E-100 T 13-09-2016 THL1_RS01115 bacc5f941dff67c011f6ea2ca4fde94f 398 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 176 342 5.3E-18 T 13-09-2016 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 THL1_RS01115 bacc5f941dff67c011f6ea2ca4fde94f 398 PANTHER PTHR11061:SF12 3 398 4.6E-100 T 13-09-2016 THL1_RS00735 98e5ce9896d26458e89c13bc80c381e3 353 Pfam PF13533 Biotin-lipoyl like 43 88 1.7E-13 T 13-09-2016 THL1_RS00735 98e5ce9896d26458e89c13bc80c381e3 353 PANTHER PTHR30367:SF6 7 353 9.1E-168 T 13-09-2016 THL1_RS00735 98e5ce9896d26458e89c13bc80c381e3 353 Gene3D G3DSA:2.40.50.100 197 229 1.5E-15 T 13-09-2016 THL1_RS00735 98e5ce9896d26458e89c13bc80c381e3 353 Gene3D G3DSA:2.40.50.100 46 77 1.5E-15 T 13-09-2016 THL1_RS00735 98e5ce9896d26458e89c13bc80c381e3 353 SUPERFAMILY SSF111369 125 162 4.58E-9 T 13-09-2016 THL1_RS00735 98e5ce9896d26458e89c13bc80c381e3 353 SUPERFAMILY SSF111369 44 96 4.58E-9 T 13-09-2016 THL1_RS00735 98e5ce9896d26458e89c13bc80c381e3 353 PANTHER PTHR30367 7 353 9.1E-168 T 13-09-2016 THL1_RS00735 98e5ce9896d26458e89c13bc80c381e3 353 SUPERFAMILY SSF111369 179 253 3.79E-6 T 13-09-2016 THL1_RS00735 98e5ce9896d26458e89c13bc80c381e3 353 Pfam PF13437 HlyD family secretion protein 200 278 9.1E-5 T 13-09-2016 THL1_RS04725 060d81ec371f5b228b1e7e928815e26e 122 Gene3D G3DSA:2.40.10.220 3 120 3.0E-45 T 13-09-2016 THL1_RS04725 060d81ec371f5b228b1e7e928815e26e 122 SUPERFAMILY SSF141371 2 119 2.67E-35 T 13-09-2016 THL1_RS04725 060d81ec371f5b228b1e7e928815e26e 122 Pfam PF07238 PilZ domain 7 103 2.9E-12 T 13-09-2016 IPR009875 PilZ domain GO:0035438 THL1_RS04725 060d81ec371f5b228b1e7e928815e26e 122 PIRSF PIRSF028141 4 122 8.1E-41 T 13-09-2016 IPR027021 Cyclic di-GMP binding protein, PA4608 type THL1_RS12545 35fd07228fd9852a34054f9c55692460 207 Pfam PF03458 UPF0126 domain 94 166 2.1E-23 T 13-09-2016 IPR005115 Uncharacterised domain UPF0126 THL1_RS12545 35fd07228fd9852a34054f9c55692460 207 Pfam PF03458 UPF0126 domain 7 80 5.2E-22 T 13-09-2016 IPR005115 Uncharacterised domain UPF0126 THL1_RS12545 35fd07228fd9852a34054f9c55692460 207 PANTHER PTHR30506 1 201 3.5E-74 T 13-09-2016 THL1_RS03185 654bcfb666643266a471a8c5c578a2d3 315 SMART SM00283 137 315 1.5E-23 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS03185 654bcfb666643266a471a8c5c578a2d3 315 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 264 293 3.8E-24 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS03185 654bcfb666643266a471a8c5c578a2d3 315 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 158 187 3.8E-24 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS03185 654bcfb666643266a471a8c5c578a2d3 315 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 235 262 3.8E-24 T 13-09-2016 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 THL1_RS03185 654bcfb666643266a471a8c5c578a2d3 315 SMART SM00304 70 122 4.4E-5 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS03185 654bcfb666643266a471a8c5c578a2d3 315 PANTHER PTHR32089:SF64 56 315 1.6E-91 T 13-09-2016 THL1_RS03185 654bcfb666643266a471a8c5c578a2d3 315 Gene3D G3DSA:1.10.287.950 151 312 1.6E-49 T 13-09-2016 THL1_RS03185 654bcfb666643266a471a8c5c578a2d3 315 PANTHER PTHR32089 56 315 1.6E-91 T 13-09-2016 THL1_RS03185 654bcfb666643266a471a8c5c578a2d3 315 SUPERFAMILY SSF58104 93 314 6.28E-60 T 13-09-2016 THL1_RS03185 654bcfb666643266a471a8c5c578a2d3 315 Pfam PF00672 HAMP domain 56 118 9.1E-11 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS03185 654bcfb666643266a471a8c5c578a2d3 315 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 187 314 1.4E-36 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS12890 e972af016593dee335381820831a7e34 591 Gene3D G3DSA:1.20.210.10 13 572 2.5E-180 T 13-09-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS12890 e972af016593dee335381820831a7e34 591 PANTHER PTHR10422:SF6 7 562 4.3E-235 T 13-09-2016 THL1_RS12890 e972af016593dee335381820831a7e34 591 PRINTS PR01165 Cytochrome c oxidase subunit I signature 310 325 2.3E-72 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS12890 e972af016593dee335381820831a7e34 591 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 121 2.3E-72 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS12890 e972af016593dee335381820831a7e34 591 PRINTS PR01165 Cytochrome c oxidase subunit I signature 264 285 2.3E-72 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS12890 e972af016593dee335381820831a7e34 591 PRINTS PR01165 Cytochrome c oxidase subunit I signature 334 355 2.3E-72 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS12890 e972af016593dee335381820831a7e34 591 PRINTS PR01165 Cytochrome c oxidase subunit I signature 69 92 2.3E-72 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS12890 e972af016593dee335381820831a7e34 591 PRINTS PR01165 Cytochrome c oxidase subunit I signature 447 468 2.3E-72 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS12890 e972af016593dee335381820831a7e34 591 PRINTS PR01165 Cytochrome c oxidase subunit I signature 21 46 2.3E-72 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS12890 e972af016593dee335381820831a7e34 591 PRINTS PR01165 Cytochrome c oxidase subunit I signature 397 416 2.3E-72 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS12890 e972af016593dee335381820831a7e34 591 PRINTS PR01165 Cytochrome c oxidase subunit I signature 369 387 2.3E-72 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS12890 e972af016593dee335381820831a7e34 591 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 22 546 1.7E-203 T 13-09-2016 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS12890 e972af016593dee335381820831a7e34 591 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 31 493 4.0E-134 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS12890 e972af016593dee335381820831a7e34 591 PANTHER PTHR10422 7 562 4.3E-235 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS12890 e972af016593dee335381820831a7e34 591 SUPERFAMILY SSF81442 19 540 2.75E-154 T 13-09-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS12890 e972af016593dee335381820831a7e34 591 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 266 320 - T 13-09-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS01370 219aa9ddc56166abf5ff97aab3d74479 163 Pfam PF04463 Protein of unknown function (DUF523) 4 149 6.7E-42 T 13-09-2016 IPR007553 Domain of unknown function DUF523 THL1_RS01370 219aa9ddc56166abf5ff97aab3d74479 163 PANTHER PTHR30087:SF1 1 160 1.5E-68 T 13-09-2016 THL1_RS01370 219aa9ddc56166abf5ff97aab3d74479 163 PANTHER PTHR30087 1 160 1.5E-68 T 13-09-2016 THL1_RS07525 a73c848f572f1b45d28cf5cf9636ee37 450 PIRSF PIRSF002744 1 449 1.3E-121 T 13-09-2016 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 THL1_RS07525 a73c848f572f1b45d28cf5cf9636ee37 450 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 11 428 2.5E-75 T 13-09-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 THL1_RS07525 a73c848f572f1b45d28cf5cf9636ee37 450 PANTHER PTHR31806 1 447 1.4E-116 T 13-09-2016 THL1_RS07525 a73c848f572f1b45d28cf5cf9636ee37 450 PANTHER PTHR31806:SF1 1 447 1.4E-116 T 13-09-2016 THL1_RS18690 72a10ad3bc859c6de3238fd8028efe1f 317 Pfam PF01479 S4 domain 23 69 3.1E-8 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS18690 72a10ad3bc859c6de3238fd8028efe1f 317 PANTHER PTHR11079 4 315 1.6E-145 T 13-09-2016 THL1_RS18690 72a10ad3bc859c6de3238fd8028efe1f 317 PANTHER PTHR11079:SF84 4 315 1.6E-145 T 13-09-2016 THL1_RS18690 72a10ad3bc859c6de3238fd8028efe1f 317 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 20 313 7.7E-78 T 13-09-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS18690 72a10ad3bc859c6de3238fd8028efe1f 317 Pfam PF00849 RNA pseudouridylate synthase 104 252 1.2E-31 T 13-09-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS18690 72a10ad3bc859c6de3238fd8028efe1f 317 SMART SM00363 23 84 1.5E-7 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS18690 72a10ad3bc859c6de3238fd8028efe1f 317 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 142 156 - T 13-09-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS18690 72a10ad3bc859c6de3238fd8028efe1f 317 SUPERFAMILY SSF55174 22 73 3.36E-8 T 13-09-2016 THL1_RS18690 72a10ad3bc859c6de3238fd8028efe1f 317 Gene3D G3DSA:3.10.290.10 23 71 2.6E-6 T 13-09-2016 IPR002942 RNA-binding S4 domain GO:0003723 THL1_RS18690 72a10ad3bc859c6de3238fd8028efe1f 317 SUPERFAMILY SSF55120 92 316 1.92E-60 T 13-09-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THL1_RS04195 6f3ae077bfcc42c2700350c03d020bbb 236 Gene3D G3DSA:3.10.300.10 16 219 4.7E-44 T 13-09-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 THL1_RS04195 6f3ae077bfcc42c2700350c03d020bbb 236 SUPERFAMILY SSF50486 15 220 2.9E-52 T 13-09-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 THL1_RS04195 6f3ae077bfcc42c2700350c03d020bbb 236 PANTHER PTHR10429:SF0 3 229 2.6E-54 T 13-09-2016 THL1_RS04195 6f3ae077bfcc42c2700350c03d020bbb 236 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 19 213 23.915 T 13-09-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 THL1_RS04195 6f3ae077bfcc42c2700350c03d020bbb 236 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 21 208 6.0E-37 T 13-09-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 THL1_RS04195 6f3ae077bfcc42c2700350c03d020bbb 236 PANTHER PTHR10429 3 229 2.6E-54 T 13-09-2016 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 THL1_RS14985 81a4425fcc7680f82e146de5bbb34c41 111 ProDom PD071248 DNA-BINDING SINGLE STRANDED DNA PHAGE PROTIEN GPV HELIX-DESTABILIZING SINGLE-STRANDED REPLICATION 7 98 0.001 T 13-09-2016 THL1_RS14925 81a4425fcc7680f82e146de5bbb34c41 111 ProDom PD071248 DNA-BINDING SINGLE STRANDED DNA PHAGE PROTIEN GPV HELIX-DESTABILIZING SINGLE-STRANDED REPLICATION 7 98 0.001 T 13-09-2016 THL1_RS05405 6cfdba014d75db7505e3cb47852851ff 155 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 4 147 1.4E-55 T 13-09-2016 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 THL1_RS05405 6cfdba014d75db7505e3cb47852851ff 155 PANTHER PTHR33371 1 146 1.3E-42 T 13-09-2016 THL1_RS05405 6cfdba014d75db7505e3cb47852851ff 155 Pfam PF02470 MlaD protein 38 116 3.4E-23 T 13-09-2016 IPR003399 Mce/MlaD THL1_RS21010 11728536ce1f871051100e7b7b2b7a40 325 SUPERFAMILY SSF159245 106 231 3.53E-13 T 13-09-2016 THL1_RS13815 86f6cef1a012b7adddfc32cdfcb041ce 140 TIGRFAM TIGR02337 HpaR: homoprotocatechuate degradation operon regulator, HpaR 7 136 6.2E-56 T 13-09-2016 IPR012712 Homoprotocatechuate degradation transcriptional regulator HpaR GO:0003677|GO:0010124|GO:0045892 THL1_RS13815 86f6cef1a012b7adddfc32cdfcb041ce 140 Pfam PF01047 MarR family 32 90 8.6E-16 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS13815 86f6cef1a012b7adddfc32cdfcb041ce 140 PANTHER PTHR33164:SF13 7 138 5.4E-66 T 13-09-2016 THL1_RS13815 86f6cef1a012b7adddfc32cdfcb041ce 140 SMART SM00347 25 125 1.2E-21 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS13815 86f6cef1a012b7adddfc32cdfcb041ce 140 SUPERFAMILY SSF46785 7 137 2.01E-29 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13815 86f6cef1a012b7adddfc32cdfcb041ce 140 PANTHER PTHR33164 7 138 5.4E-66 T 13-09-2016 THL1_RS13815 86f6cef1a012b7adddfc32cdfcb041ce 140 Gene3D G3DSA:1.10.10.10 5 137 2.9E-34 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS28365 0f454d3b3fc6c158459a4b1122b81bd8 324 PANTHER PTHR13748 5 323 2.8E-44 T 13-09-2016 THL1_RS28365 0f454d3b3fc6c158459a4b1122b81bd8 324 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 169 1.1E-34 T 13-09-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain THL1_RS28365 0f454d3b3fc6c158459a4b1122b81bd8 324 SUPERFAMILY SSF52540 6 187 5.06E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS28365 0f454d3b3fc6c158459a4b1122b81bd8 324 Gene3D G3DSA:3.40.50.300 4 195 2.2E-38 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS10025 7ce2f8624c9af7f2fb5796b0d211658c 254 PANTHER PTHR10108:SF835 10 249 2.2E-94 T 13-09-2016 THL1_RS10025 7ce2f8624c9af7f2fb5796b0d211658c 254 Gene3D G3DSA:3.40.50.150 42 253 6.1E-50 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS10025 7ce2f8624c9af7f2fb5796b0d211658c 254 SUPERFAMILY SSF53335 11 241 1.18E-46 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS10025 7ce2f8624c9af7f2fb5796b0d211658c 254 Pfam PF08241 Methyltransferase domain 49 145 5.3E-25 T 13-09-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 THL1_RS10025 7ce2f8624c9af7f2fb5796b0d211658c 254 PANTHER PTHR10108 10 249 2.2E-94 T 13-09-2016 THL1_RS11230 5a69b727845f406a22192114be64d3cd 183 PANTHER PTHR30042:SF2 1 181 8.2E-77 T 13-09-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 THL1_RS11230 5a69b727845f406a22192114be64d3cd 183 PANTHER PTHR30042 1 181 8.2E-77 T 13-09-2016 THL1_RS11230 5a69b727845f406a22192114be64d3cd 183 Pfam PF02669 K+-transporting ATPase, c chain 6 179 8.9E-64 T 13-09-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 THL1_RS11230 5a69b727845f406a22192114be64d3cd 183 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 2 181 32.987 T 13-09-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 THL1_RS11230 5a69b727845f406a22192114be64d3cd 183 PIRSF PIRSF001296 1 183 3.1E-66 T 13-09-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 THL1_RS11230 5a69b727845f406a22192114be64d3cd 183 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 3 180 5.0E-56 T 13-09-2016 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 THL1_RS28125 c283aef79cba37bb436224df687d1efc 314 Gene3D G3DSA:2.60.40.1090 180 314 1.1E-14 T 13-09-2016 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 THL1_RS28125 c283aef79cba37bb436224df687d1efc 314 PANTHER PTHR33420 185 314 4.8E-14 T 13-09-2016 THL1_RS28125 c283aef79cba37bb436224df687d1efc 314 SUPERFAMILY SSF49401 176 314 7.46E-15 T 13-09-2016 IPR008966 Adhesion domain THL1_RS27200 a721623cab3a01ee40bc7801f73f2e42 148 PANTHER PTHR33507 1 148 9.8E-42 T 13-09-2016 THL1_RS27200 a721623cab3a01ee40bc7801f73f2e42 148 PANTHER PTHR33507:SF3 1 148 9.8E-42 T 13-09-2016 THL1_RS27200 a721623cab3a01ee40bc7801f73f2e42 148 Gene3D G3DSA:2.40.50.140 94 148 2.7E-8 T 13-09-2016 IPR012340 Nucleic acid-binding, OB-fold THL1_RS27200 a721623cab3a01ee40bc7801f73f2e42 148 Pfam PF01957 NfeD-like C-terminal, partner-binding 13 147 1.7E-29 T 13-09-2016 IPR002810 NfeD-like, C-terminal domain THL1_RS12215 ce007783bb7054774b0c94d6fe1e895a 439 Pfam PF13726 Na+-H+ antiporter family 2 88 4.0E-31 T 13-09-2016 IPR032813 Putative Na+/H+ antiporter, N-terminal THL1_RS12215 ce007783bb7054774b0c94d6fe1e895a 439 Pfam PF03553 Na+/H+ antiporter family 149 433 1.4E-76 T 13-09-2016 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 THL1_RS12215 ce007783bb7054774b0c94d6fe1e895a 439 PRINTS PR00173 Glutamate-aspartate symporter signature 15 35 1.0E-5 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS12215 ce007783bb7054774b0c94d6fe1e895a 439 PRINTS PR00173 Glutamate-aspartate symporter signature 251 270 1.0E-5 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS12215 ce007783bb7054774b0c94d6fe1e895a 439 PRINTS PR00173 Glutamate-aspartate symporter signature 372 391 1.0E-5 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS12215 ce007783bb7054774b0c94d6fe1e895a 439 PRINTS PR00173 Glutamate-aspartate symporter signature 95 120 1.0E-5 T 13-09-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 THL1_RS12215 ce007783bb7054774b0c94d6fe1e895a 439 PANTHER PTHR37821 1 439 3.8E-197 T 13-09-2016 THL1_RS04430 d05caddb56a7873a1b029470bcbe8ce5 465 SUPERFAMILY SSF50475 10 304 6.67E-76 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS04430 d05caddb56a7873a1b029470bcbe8ce5 465 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 25 433 2.7E-84 T 13-09-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 THL1_RS04430 d05caddb56a7873a1b029470bcbe8ce5 465 PANTHER PTHR30108 8 448 2.4E-82 T 13-09-2016 THL1_RS04430 d05caddb56a7873a1b029470bcbe8ce5 465 Gene3D G3DSA:3.40.1670.10 322 433 4.8E-33 T 13-09-2016 THL1_RS04430 d05caddb56a7873a1b029470bcbe8ce5 465 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 25 409 6.4E-96 T 13-09-2016 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978|UniPathway: UPA00232 THL1_RS04430 d05caddb56a7873a1b029470bcbe8ce5 465 PANTHER PTHR30108:SF1 8 448 2.4E-82 T 13-09-2016 THL1_RS04430 d05caddb56a7873a1b029470bcbe8ce5 465 SUPERFAMILY SSF143968 310 459 9.42E-40 T 13-09-2016 THL1_RS08395 20507b225275b094cb77e8ec943f2b56 140 Gene3D G3DSA:3.10.180.10 6 135 1.4E-24 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS08395 20507b225275b094cb77e8ec943f2b56 140 PANTHER PTHR34109:SF3 10 139 3.0E-56 T 13-09-2016 THL1_RS08395 20507b225275b094cb77e8ec943f2b56 140 SUPERFAMILY SSF54593 15 139 5.1E-24 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS08395 20507b225275b094cb77e8ec943f2b56 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 133 1.4E-8 T 13-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain THL1_RS08395 20507b225275b094cb77e8ec943f2b56 140 PANTHER PTHR34109 10 139 3.0E-56 T 13-09-2016 THL1_RS27425 d738a5f0f235e404739e9efdc7bef998 359 Gene3D G3DSA:2.120.10.30 13 356 1.2E-72 T 13-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like THL1_RS27425 d738a5f0f235e404739e9efdc7bef998 359 PANTHER PTHR19328:SF33 23 359 8.0E-99 T 13-09-2016 THL1_RS27425 d738a5f0f235e404739e9efdc7bef998 359 SUPERFAMILY SSF50952 21 357 7.98E-41 T 13-09-2016 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 THL1_RS27425 d738a5f0f235e404739e9efdc7bef998 359 Pfam PF07995 Glucose / Sorbosone dehydrogenase 119 353 8.5E-18 T 13-09-2016 IPR012938 Glucose/Sorbosone dehydrogenase GO:0005975|GO:0016901|GO:0048038 THL1_RS27425 d738a5f0f235e404739e9efdc7bef998 359 PANTHER PTHR19328 23 359 8.0E-99 T 13-09-2016 THL1_RS05110 424eaf20bb22dc855270e5f8ba9776fb 760 Pfam PF07793 Protein of unknown function (DUF1631) 24 754 1.7E-259 T 13-09-2016 IPR012434 Protein of unknown function DUF1631 THL1_RS16545 398a2ef33e7b2ae8e76b0313f7f28dae 499 SUPERFAMILY SSF53720 11 491 1.11E-159 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS16545 398a2ef33e7b2ae8e76b0313f7f28dae 499 Gene3D G3DSA:3.40.605.10 17 277 1.7E-91 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS16545 398a2ef33e7b2ae8e76b0313f7f28dae 499 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS16545 398a2ef33e7b2ae8e76b0313f7f28dae 499 PANTHER PTHR11699 2 492 8.6E-213 T 13-09-2016 THL1_RS16545 398a2ef33e7b2ae8e76b0313f7f28dae 499 Gene3D G3DSA:3.40.309.10 278 454 4.4E-66 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS16545 398a2ef33e7b2ae8e76b0313f7f28dae 499 Pfam PF00171 Aldehyde dehydrogenase family 33 487 2.7E-166 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS10040 7e4ecdb3b1b3aa9a8e5ce350db385a18 342 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 7 117 9.3E-23 T 13-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THL1_RS10040 7e4ecdb3b1b3aa9a8e5ce350db385a18 342 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 140 319 4.7E-40 T 13-09-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 THL1_RS10040 7e4ecdb3b1b3aa9a8e5ce350db385a18 342 PIRSF PIRSF000148 4 338 4.8E-83 T 13-09-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 THL1_RS10040 7e4ecdb3b1b3aa9a8e5ce350db385a18 342 Gene3D G3DSA:3.30.360.10 144 315 2.8E-49 T 13-09-2016 THL1_RS10040 7e4ecdb3b1b3aa9a8e5ce350db385a18 342 SUPERFAMILY SSF55347 131 320 1.78E-47 T 13-09-2016 THL1_RS10040 7e4ecdb3b1b3aa9a8e5ce350db385a18 342 Gene3D G3DSA:3.40.50.720 1 143 2.9E-39 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10040 7e4ecdb3b1b3aa9a8e5ce350db385a18 342 SUPERFAMILY SSF51735 5 154 5.12E-37 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10040 7e4ecdb3b1b3aa9a8e5ce350db385a18 342 PANTHER PTHR10174 58 337 8.2E-30 T 13-09-2016 THL1_RS10040 7e4ecdb3b1b3aa9a8e5ce350db385a18 342 PANTHER PTHR10174:SF2 58 337 8.2E-30 T 13-09-2016 THL1_RS10040 7e4ecdb3b1b3aa9a8e5ce350db385a18 342 SMART SM00859 6 120 1.5E-22 T 13-09-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THL1_RS04540 9bfe6994d31b02a0f145101dd8c1e392 270 PANTHER PTHR30222:SF7 11 115 2.8E-56 T 13-09-2016 THL1_RS04540 9bfe6994d31b02a0f145101dd8c1e392 270 PANTHER PTHR30222 11 115 2.8E-56 T 13-09-2016 THL1_RS04540 9bfe6994d31b02a0f145101dd8c1e392 270 PANTHER PTHR30222 133 267 2.8E-56 T 13-09-2016 THL1_RS04540 9bfe6994d31b02a0f145101dd8c1e392 270 SUPERFAMILY SSF161098 9 258 5.34E-47 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS04540 9bfe6994d31b02a0f145101dd8c1e392 270 PANTHER PTHR30222:SF7 133 267 2.8E-56 T 13-09-2016 THL1_RS04540 9bfe6994d31b02a0f145101dd8c1e392 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 264 6.5E-15 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS04540 9bfe6994d31b02a0f145101dd8c1e392 270 Gene3D G3DSA:1.10.3720.10 2 267 7.9E-55 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS14680 a143b623ed44be5005a12d0fb7365f63 420 Gene3D G3DSA:3.40.50.880 27 279 1.1E-16 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS14680 a143b623ed44be5005a12d0fb7365f63 420 PIRSF PIRSF032067 5 411 4.7E-67 T 13-09-2016 IPR011811 Peptidase S51, cyanophycinase GO:0016787|GO:0044260 MetaCyc: PWY-7052 THL1_RS14680 a143b623ed44be5005a12d0fb7365f63 420 PANTHER PTHR36175 25 358 5.8E-52 T 13-09-2016 THL1_RS14680 a143b623ed44be5005a12d0fb7365f63 420 Pfam PF03575 Peptidase family S51 81 258 7.5E-7 T 13-09-2016 IPR005320 Peptidase S51 GO:0006508|GO:0008236 THL1_RS14680 a143b623ed44be5005a12d0fb7365f63 420 SUPERFAMILY SSF52317 40 259 4.01E-13 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS05995 2c949225aaf47b38442cd58f3e6d5779 212 PANTHER PTHR38035 1 209 1.5E-80 T 13-09-2016 THL1_RS05995 2c949225aaf47b38442cd58f3e6d5779 212 Gene3D G3DSA:1.25.40.10 98 195 3.0E-6 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS05995 2c949225aaf47b38442cd58f3e6d5779 212 PIRSF PIRSF006170 1 212 1.5E-65 T 13-09-2016 IPR026039 Uncharacterised protein family UPF0070 THL1_RS05995 2c949225aaf47b38442cd58f3e6d5779 212 Pfam PF09976 Tetratricopeptide repeat-like domain 12 209 1.5E-61 T 13-09-2016 IPR018704 Tetratricopeptide repeat-like domain THL1_RS05995 2c949225aaf47b38442cd58f3e6d5779 212 SUPERFAMILY SSF48452 97 194 1.84E-7 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS10085 a8b05906951a06517211cc5ebc636fb5 161 Pfam PF14499 Domain of unknown function (DUF4437) 56 136 6.3E-6 T 13-09-2016 IPR028013 Protein of unknown function DUF4437 THL1_RS10085 a8b05906951a06517211cc5ebc636fb5 161 Gene3D G3DSA:2.60.120.10 38 158 7.0E-14 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS10085 a8b05906951a06517211cc5ebc636fb5 161 SUPERFAMILY SSF51182 38 159 2.59E-18 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS23755 be896b22521960a006de370d839cce30 458 Pfam PF07044 Protein of unknown function (DUF1329) 86 453 4.1E-120 T 13-09-2016 IPR010752 Protein of unknown function DUF1329 THL1_RS23755 be896b22521960a006de370d839cce30 458 Gene3D G3DSA:2.50.20.10 346 444 2.7E-37 T 13-09-2016 THL1_RS23755 be896b22521960a006de370d839cce30 458 Gene3D G3DSA:2.50.20.10 162 312 2.7E-37 T 13-09-2016 THL1_RS21950 af095286ba1b1494a00edfb60ca6e67a 74 Gene3D G3DSA:3.90.1680.10 11 72 2.4E-9 T 13-09-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS21950 af095286ba1b1494a00edfb60ca6e67a 74 SUPERFAMILY SSF143081 11 73 3.01E-10 T 13-09-2016 IPR003738 SOS response associated peptidase (SRAP) KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- THL1_RS11260 208787a1b214096c738957862582efeb 346 PANTHER PTHR11019:SF52 240 342 1.8E-29 T 13-09-2016 THL1_RS11260 208787a1b214096c738957862582efeb 346 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 25 209 2.2E-44 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS11260 208787a1b214096c738957862582efeb 346 SMART SM00342 251 334 1.8E-20 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS11260 208787a1b214096c738957862582efeb 346 Gene3D G3DSA:1.10.10.60 291 338 5.9E-14 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS11260 208787a1b214096c738957862582efeb 346 PANTHER PTHR11019 240 342 1.8E-29 T 13-09-2016 THL1_RS11260 208787a1b214096c738957862582efeb 346 Pfam PF12833 Helix-turn-helix domain 258 334 3.2E-16 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS11260 208787a1b214096c738957862582efeb 346 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 318 334 6.6E-6 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS11260 208787a1b214096c738957862582efeb 346 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 303 318 6.6E-6 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS11260 208787a1b214096c738957862582efeb 346 SUPERFAMILY SSF46689 291 335 1.3E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS24135 b810530591bdf93ae42cbb34c4de4494 220 PANTHER PTHR30462:SF1 12 213 3.4E-27 T 13-09-2016 THL1_RS24135 b810530591bdf93ae42cbb34c4de4494 220 Pfam PF04403 Paraquat-inducible protein A 58 210 1.7E-47 T 13-09-2016 IPR007498 Paraquat-inducible protein A THL1_RS24135 b810530591bdf93ae42cbb34c4de4494 220 PANTHER PTHR30462 12 213 3.4E-27 T 13-09-2016 THL1_RS17835 0f6325811acfcfb315c083d79b062cd7 559 SUPERFAMILY SSF47226 436 548 2.03E-7 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS17835 0f6325811acfcfb315c083d79b062cd7 559 Gene3D G3DSA:1.20.120.160 13 133 7.2E-6 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS17835 0f6325811acfcfb315c083d79b062cd7 559 SUPERFAMILY SSF47226 8 128 5.89E-9 T 13-09-2016 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 THL1_RS16650 daae19ca1bed047c36798b7f06b83f02 268 TIGRFAM TIGR02391 hypoth_ymh: TIGR02391 family protein 143 265 1.8E-36 T 13-09-2016 IPR012654 Conserved hypothetical protein CHP02391 THL1_RS16650 daae19ca1bed047c36798b7f06b83f02 268 Pfam PF09509 Protein of unknown function (Hypoth_ymh) 141 261 3.4E-41 T 13-09-2016 IPR012654 Conserved hypothetical protein CHP02391 THL1_RS25335 66fd1003b6f091e8c04a135956006a7d 294 PANTHER PTHR35007 55 292 2.0E-53 T 13-09-2016 THL1_RS25335 66fd1003b6f091e8c04a135956006a7d 294 Pfam PF00482 Type II secretion system (T2SS), protein F 128 253 3.2E-15 T 13-09-2016 IPR018076 Type II secretion system F domain THL1_RS25335 66fd1003b6f091e8c04a135956006a7d 294 PANTHER PTHR35007:SF1 55 292 2.0E-53 T 13-09-2016 THL1_RS02145 38546bc1f9dcaa0159ce8b626471c3c7 324 SUPERFAMILY SSF56112 1 322 8.16E-88 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS02145 38546bc1f9dcaa0159ce8b626471c3c7 324 PANTHER PTHR39573:SF1 1 324 8.5E-174 T 13-09-2016 IPR032882 SrkA/RdoA protein kinase GO:0004674|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 THL1_RS02145 38546bc1f9dcaa0159ce8b626471c3c7 324 PANTHER PTHR39573 1 324 8.5E-174 T 13-09-2016 THL1_RS02145 38546bc1f9dcaa0159ce8b626471c3c7 324 Pfam PF01636 Phosphotransferase enzyme family 32 261 1.7E-38 T 13-09-2016 IPR002575 Aminoglycoside phosphotransferase THL1_RS02145 38546bc1f9dcaa0159ce8b626471c3c7 324 Gene3D G3DSA:3.90.1200.10 104 322 4.3E-44 T 13-09-2016 THL1_RS02145 38546bc1f9dcaa0159ce8b626471c3c7 324 Hamap MF_01497 Stress response kinase A [srkA]. 1 317 48.133 T 13-09-2016 IPR032882 SrkA/RdoA protein kinase GO:0004674|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 THL1_RS15510 bbceae69b3de07cf45cf099f831e3b53 406 Gene3D G3DSA:2.130.10.10 15 348 1.4E-91 T 13-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THL1_RS15510 bbceae69b3de07cf45cf099f831e3b53 406 Pfam PF06433 Methylamine dehydrogenase heavy chain (MADH) 64 347 4.5E-38 T 13-09-2016 IPR009451 Amine dehydrogenase heavy chain GO:0030058|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 THL1_RS15510 bbceae69b3de07cf45cf099f831e3b53 406 SUPERFAMILY SSF50969 12 403 6.02E-70 T 13-09-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like THL1_RS24320 ec76877c1be759dcbeb4d42b5ed2327d 554 Gene3D G3DSA:1.10.1390.10 511 551 1.6E-17 T 13-09-2016 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 THL1_RS24320 ec76877c1be759dcbeb4d42b5ed2327d 554 Pfam PF00342 Phosphoglucose isomerase 55 545 4.8E-192 T 13-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 THL1_RS24320 ec76877c1be759dcbeb4d42b5ed2327d 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 153 172 2.7E-52 T 13-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 THL1_RS24320 ec76877c1be759dcbeb4d42b5ed2327d 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 501 514 2.7E-52 T 13-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 THL1_RS24320 ec76877c1be759dcbeb4d42b5ed2327d 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 342 363 2.7E-52 T 13-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 THL1_RS24320 ec76877c1be759dcbeb4d42b5ed2327d 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 487 501 2.7E-52 T 13-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 THL1_RS24320 ec76877c1be759dcbeb4d42b5ed2327d 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 265 283 2.7E-52 T 13-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 THL1_RS24320 ec76877c1be759dcbeb4d42b5ed2327d 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 469 487 2.7E-52 T 13-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 THL1_RS24320 ec76877c1be759dcbeb4d42b5ed2327d 554 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 501 518 - T 13-09-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 THL1_RS24320 ec76877c1be759dcbeb4d42b5ed2327d 554 Gene3D G3DSA:3.40.50.10490 102 294 3.2E-75 T 13-09-2016 THL1_RS24320 ec76877c1be759dcbeb4d42b5ed2327d 554 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 49 528 40.66 T 13-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 THL1_RS24320 ec76877c1be759dcbeb4d42b5ed2327d 554 SUPERFAMILY SSF53697 9 551 1.08E-205 T 13-09-2016 THL1_RS24320 ec76877c1be759dcbeb4d42b5ed2327d 554 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 269 282 - T 13-09-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 THL1_RS24320 ec76877c1be759dcbeb4d42b5ed2327d 554 Gene3D G3DSA:3.40.50.10490 12 101 2.1E-129 T 13-09-2016 THL1_RS24320 ec76877c1be759dcbeb4d42b5ed2327d 554 Gene3D G3DSA:3.40.50.10490 297 510 2.1E-129 T 13-09-2016 THL1_RS24320 ec76877c1be759dcbeb4d42b5ed2327d 554 PANTHER PTHR11469 2 550 4.5E-277 T 13-09-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 THL1_RS28295 f7003995597d3111873610038bb0ceab 463 SUPERFAMILY SSF53383 44 455 3.2E-85 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS28295 f7003995597d3111873610038bb0ceab 463 Gene3D G3DSA:3.40.640.10 95 344 3.7E-46 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS28295 f7003995597d3111873610038bb0ceab 463 PANTHER PTHR11986 1 460 3.3E-235 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS28295 f7003995597d3111873610038bb0ceab 463 Pfam PF00202 Aminotransferase class-III 50 451 1.4E-38 T 13-09-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THL1_RS28295 f7003995597d3111873610038bb0ceab 463 PANTHER PTHR11986:SF74 1 460 3.3E-235 T 13-09-2016 THL1_RS28295 f7003995597d3111873610038bb0ceab 463 Gene3D G3DSA:3.90.1150.10 349 454 1.6E-22 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS28295 f7003995597d3111873610038bb0ceab 463 Gene3D G3DSA:3.90.1150.10 22 93 1.6E-22 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS03915 33fd12f44794f080411b688ef466469f 119 PANTHER PTHR40455:SF1 3 118 6.3E-16 T 13-09-2016 THL1_RS03915 33fd12f44794f080411b688ef466469f 119 Gene3D G3DSA:1.10.260.40 42 115 5.6E-10 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS03915 33fd12f44794f080411b688ef466469f 119 PANTHER PTHR40455 3 118 6.3E-16 T 13-09-2016 THL1_RS15790 89320cdf8fbc363e87b29d3bae578059 288 Pfam PF13714 Phosphoenolpyruvate phosphomutase 13 248 2.5E-41 T 13-09-2016 THL1_RS15790 89320cdf8fbc363e87b29d3bae578059 288 Gene3D G3DSA:3.20.20.60 8 253 3.3E-56 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS15790 89320cdf8fbc363e87b29d3bae578059 288 PANTHER PTHR21631:SF19 10 288 5.9E-147 T 13-09-2016 THL1_RS15790 89320cdf8fbc363e87b29d3bae578059 288 SUPERFAMILY SSF51621 8 285 5.38E-62 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS15790 89320cdf8fbc363e87b29d3bae578059 288 Hamap MF_01299 Oxaloacetate decarboxylase. 4 288 44.93 T 13-09-2016 IPR023687 Oxaloacetate decarboxylase, bacterial GO:0008948 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 THL1_RS15790 89320cdf8fbc363e87b29d3bae578059 288 PANTHER PTHR21631 10 288 5.9E-147 T 13-09-2016 THL1_RS07680 82dec7b2f92b91621e1d268a301a42a3 287 Gene3D G3DSA:1.10.287.950 86 281 6.9E-44 T 13-09-2016 THL1_RS07680 82dec7b2f92b91621e1d268a301a42a3 287 SMART SM00283 80 287 1.8E-13 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS07680 82dec7b2f92b91621e1d268a301a42a3 287 SUPERFAMILY SSF58104 84 282 1.27E-47 T 13-09-2016 THL1_RS07680 82dec7b2f92b91621e1d268a301a42a3 287 PANTHER PTHR32089 83 274 1.0E-42 T 13-09-2016 THL1_RS07680 82dec7b2f92b91621e1d268a301a42a3 287 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 129 270 5.6E-34 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS19020 c406dd72d6418f24387129902418e131 449 PANTHER PTHR11785:SF341 3 439 3.6E-133 T 13-09-2016 THL1_RS19020 c406dd72d6418f24387129902418e131 449 Pfam PF13520 Amino acid permease 12 405 3.6E-44 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS19020 c406dd72d6418f24387129902418e131 449 PANTHER PTHR11785 3 439 3.6E-133 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS19020 c406dd72d6418f24387129902418e131 449 PIRSF PIRSF006060 1 447 7.3E-54 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS15935 a17e284d4b4acbae0a0ffe4f984fe3c6 198 Gene3D G3DSA:3.40.50.880 1 188 1.3E-45 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS15935 a17e284d4b4acbae0a0ffe4f984fe3c6 198 SUPERFAMILY SSF52317 1 173 8.02E-26 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS15935 a17e284d4b4acbae0a0ffe4f984fe3c6 198 Pfam PF01965 DJ-1/PfpI family 1 161 2.4E-11 T 13-09-2016 IPR002818 DJ-1/PfpI THL1_RS02840 717b000e63bd2aed597538d731c3cd02 147 Gene3D G3DSA:3.30.450.20 4 129 5.5E-35 T 13-09-2016 THL1_RS02840 717b000e63bd2aed597538d731c3cd02 147 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 23 122 1.9E-8 T 13-09-2016 IPR000014 PAS domain THL1_RS02840 717b000e63bd2aed597538d731c3cd02 147 SUPERFAMILY SSF55785 8 118 1.1E-19 T 13-09-2016 IPR000014 PAS domain THL1_RS02840 717b000e63bd2aed597538d731c3cd02 147 Pfam PF08447 PAS fold 22 110 7.8E-24 T 13-09-2016 IPR013655 PAS fold-3 GO:0005515 THL1_RS02840 717b000e63bd2aed597538d731c3cd02 147 SMART SM00086 74 117 3.7E-6 T 13-09-2016 IPR001610 PAC motif THL1_RS14270 f6edcc91d0dbd213fc6d0475157fda91 93 Hamap MF_00655 Coenzyme PQQ synthesis protein D [pqqD]. 4 91 26.073 T 13-09-2016 IPR022479 Coenzyme PQQ synthesis D, bacteria GO:0018189|GO:0048038 UniPathway: UPA00539 THL1_RS14270 f6edcc91d0dbd213fc6d0475157fda91 93 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 26 86 3.5E-14 T 13-09-2016 IPR008792 Coenzyme PQQ synthesis D UniPathway: UPA00539 THL1_RS14270 f6edcc91d0dbd213fc6d0475157fda91 93 TIGRFAM TIGR03859 PQQ_PqqD: coenzyme PQQ biosynthesis protein PqqD 10 90 1.1E-35 T 13-09-2016 IPR022479 Coenzyme PQQ synthesis D, bacteria GO:0018189|GO:0048038 UniPathway: UPA00539 THL1_RS20185 3956ce2ec9fe2b79802b928c349827f7 437 SUPERFAMILY SSF56935 286 437 9.16E-16 T 13-09-2016 THL1_RS20185 3956ce2ec9fe2b79802b928c349827f7 437 SUPERFAMILY SSF56935 50 251 9.16E-16 T 13-09-2016 THL1_RS20185 3956ce2ec9fe2b79802b928c349827f7 437 Pfam PF07396 Phosphate-selective porin O and P 53 437 2.0E-85 T 13-09-2016 IPR010870 Phosphate-selective porin O/P THL1_RS20185 3956ce2ec9fe2b79802b928c349827f7 437 Gene3D G3DSA:2.40.160.10 27 437 2.9E-103 T 13-09-2016 IPR023614 Porin domain THL1_RS19295 4d61b18b540fbc893b2655748e136e37 185 Gene3D G3DSA:3.40.109.10 1 183 9.1E-39 T 13-09-2016 IPR000415 Nitroreductase-like GO:0016491 THL1_RS19295 4d61b18b540fbc893b2655748e136e37 185 Pfam PF00881 Nitroreductase family 16 163 2.7E-24 T 13-09-2016 IPR029479 Nitroreductase THL1_RS19295 4d61b18b540fbc893b2655748e136e37 185 PANTHER PTHR23026:SF107 1 174 3.3E-70 T 13-09-2016 THL1_RS19295 4d61b18b540fbc893b2655748e136e37 185 PIRSF PIRSF000232 1 185 1.8E-65 T 13-09-2016 IPR026021 Putative NAD(P)H nitroreductase YdjA-like KEGG: 00231+1.-.-.-|KEGG: 00592+1.-.-.-|KEGG: 00633+1.-.-.-|KEGG: 00780+1.-.-.-|KEGG: 00860+1.-.-.-|KEGG: 00950+1.-.-.-|KEGG: 00981+1.-.-.- THL1_RS19295 4d61b18b540fbc893b2655748e136e37 185 PANTHER PTHR23026 1 174 3.3E-70 T 13-09-2016 THL1_RS19295 4d61b18b540fbc893b2655748e136e37 185 SUPERFAMILY SSF55469 1 182 1.3E-39 T 13-09-2016 IPR000415 Nitroreductase-like GO:0016491 THL1_RS09915 81357bc1d5319d607f59ddb4fe416a17 299 SUPERFAMILY SSF103481 192 298 4.84E-11 T 13-09-2016 THL1_RS09915 81357bc1d5319d607f59ddb4fe416a17 299 PANTHER PTHR32322:SF8 2 294 3.9E-32 T 13-09-2016 THL1_RS09915 81357bc1d5319d607f59ddb4fe416a17 299 SUPERFAMILY SSF103481 46 146 4.45E-11 T 13-09-2016 THL1_RS09915 81357bc1d5319d607f59ddb4fe416a17 299 PANTHER PTHR32322 2 294 3.9E-32 T 13-09-2016 THL1_RS09915 81357bc1d5319d607f59ddb4fe416a17 299 Pfam PF00892 EamA-like transporter family 161 296 1.6E-15 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS09915 81357bc1d5319d607f59ddb4fe416a17 299 Pfam PF00892 EamA-like transporter family 20 143 1.4E-12 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS08635 7b82c71bed6e0c9fbe2dde6c68383bc8 184 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 26 182 1.0E-48 T 13-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THL1_RS08635 7b82c71bed6e0c9fbe2dde6c68383bc8 184 PANTHER PTHR11071 21 181 3.4E-78 T 13-09-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 THL1_RS08635 7b82c71bed6e0c9fbe2dde6c68383bc8 184 SUPERFAMILY SSF50891 22 182 2.34E-59 T 13-09-2016 IPR029000 Cyclophilin-like domain THL1_RS08635 7b82c71bed6e0c9fbe2dde6c68383bc8 184 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 65 77 8.0E-12 T 13-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THL1_RS08635 7b82c71bed6e0c9fbe2dde6c68383bc8 184 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 139 154 8.0E-12 T 13-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THL1_RS08635 7b82c71bed6e0c9fbe2dde6c68383bc8 184 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 39 54 8.0E-12 T 13-09-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 THL1_RS08635 7b82c71bed6e0c9fbe2dde6c68383bc8 184 PANTHER PTHR11071:SF265 21 181 3.4E-78 T 13-09-2016 THL1_RS08635 7b82c71bed6e0c9fbe2dde6c68383bc8 184 Gene3D G3DSA:2.40.100.10 22 182 4.1E-56 T 13-09-2016 IPR029000 Cyclophilin-like domain THL1_RS08635 7b82c71bed6e0c9fbe2dde6c68383bc8 184 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 60 77 - T 13-09-2016 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 THL1_RS22960 4aa08e19f862dec8c19d7dac42dc1721 341 Pfam PF08402 TOBE domain 257 335 2.5E-13 T 13-09-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 THL1_RS22960 4aa08e19f862dec8c19d7dac42dc1721 341 PANTHER PTHR24220:SF150 6 277 1.8E-139 T 13-09-2016 THL1_RS22960 4aa08e19f862dec8c19d7dac42dc1721 341 PANTHER PTHR24220 6 277 1.8E-139 T 13-09-2016 THL1_RS22960 4aa08e19f862dec8c19d7dac42dc1721 341 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS22960 4aa08e19f862dec8c19d7dac42dc1721 341 SUPERFAMILY SSF52540 5 243 2.21E-85 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22960 4aa08e19f862dec8c19d7dac42dc1721 341 SUPERFAMILY SSF50331 249 336 1.19E-7 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS22960 4aa08e19f862dec8c19d7dac42dc1721 341 Gene3D G3DSA:3.40.50.300 4 234 3.6E-78 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS22960 4aa08e19f862dec8c19d7dac42dc1721 341 Pfam PF00005 ABC transporter 21 162 7.2E-33 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS22960 4aa08e19f862dec8c19d7dac42dc1721 341 SMART SM00382 29 212 8.3E-20 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS08530 8060bf0f73e906966981fe1e15bedb97 418 Pfam PF11862 Domain of unknown function (DUF3382) 4 105 3.3E-20 T 13-09-2016 IPR021807 High-affinity branched-chain amino acid transport system permease, LivHM, N-terminal THL1_RS08530 8060bf0f73e906966981fe1e15bedb97 418 PANTHER PTHR30482:SF9 62 418 5.0E-188 T 13-09-2016 THL1_RS08530 8060bf0f73e906966981fe1e15bedb97 418 PANTHER PTHR30482 62 418 5.0E-188 T 13-09-2016 THL1_RS08530 8060bf0f73e906966981fe1e15bedb97 418 Pfam PF02653 Branched-chain amino acid transport system / permease component 114 399 3.7E-53 T 13-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 THL1_RS17080 23ac72598fa030c4fcb15854eeca6f2d 277 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 9 223 5.2E-18 T 13-09-2016 IPR008775 Phytanoyl-CoA dioxygenase THL1_RS17080 23ac72598fa030c4fcb15854eeca6f2d 277 SUPERFAMILY SSF51197 3 248 1.44E-46 T 13-09-2016 THL1_RS17080 23ac72598fa030c4fcb15854eeca6f2d 277 PANTHER PTHR20883 1 243 8.5E-22 T 13-09-2016 THL1_RS17080 23ac72598fa030c4fcb15854eeca6f2d 277 Gene3D G3DSA:2.60.120.620 3 239 3.9E-37 T 13-09-2016 THL1_RS22725 82d5865f91dd0affa5fe9a7e21fb36b0 244 PANTHER PTHR30294:SF5 1 240 3.1E-104 T 13-09-2016 THL1_RS22725 82d5865f91dd0affa5fe9a7e21fb36b0 244 Pfam PF12679 ABC-2 family transporter protein 67 237 2.4E-10 T 13-09-2016 IPR032688 ABC-2 family transporter protein GO:0006810 THL1_RS22725 82d5865f91dd0affa5fe9a7e21fb36b0 244 PANTHER PTHR30294 1 240 3.1E-104 T 13-09-2016 THL1_RS07215 9b9b41ef1a156d6e2a179488a751c75b 286 PANTHER PTHR31157 10 286 9.3E-51 T 13-09-2016 THL1_RS07215 9b9b41ef1a156d6e2a179488a751c75b 286 PANTHER PTHR31157:SF1 10 286 9.3E-51 T 13-09-2016 THL1_RS07215 9b9b41ef1a156d6e2a179488a751c75b 286 SUPERFAMILY SSF55797 154 284 7.06E-24 T 13-09-2016 IPR014044 CAP domain THL1_RS07215 9b9b41ef1a156d6e2a179488a751c75b 286 Pfam PF00188 Cysteine-rich secretory protein family 157 283 1.0E-22 T 13-09-2016 IPR014044 CAP domain THL1_RS07215 9b9b41ef1a156d6e2a179488a751c75b 286 Gene3D G3DSA:3.40.33.10 151 282 9.6E-14 T 13-09-2016 IPR014044 CAP domain THL1_RS14450 b76a88c6217771c696cad5a4c2d1641d 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 312 5.8E-41 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS14450 b76a88c6217771c696cad5a4c2d1641d 400 Gene3D G3DSA:3.50.50.60 1 108 8.4E-12 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS14450 b76a88c6217771c696cad5a4c2d1641d 400 Gene3D G3DSA:3.50.50.60 109 322 3.8E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS14450 b76a88c6217771c696cad5a4c2d1641d 400 SUPERFAMILY SSF51905 207 327 2.3E-29 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS14450 b76a88c6217771c696cad5a4c2d1641d 400 SUPERFAMILY SSF51905 2 166 2.3E-29 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS14450 b76a88c6217771c696cad5a4c2d1641d 400 PANTHER PTHR22912 64 330 4.6E-23 T 13-09-2016 THL1_RS14450 b76a88c6217771c696cad5a4c2d1641d 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 2.9E-12 T 13-09-2016 THL1_RS14450 b76a88c6217771c696cad5a4c2d1641d 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 2.9E-12 T 13-09-2016 THL1_RS14450 b76a88c6217771c696cad5a4c2d1641d 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.9E-12 T 13-09-2016 THL1_RS14450 b76a88c6217771c696cad5a4c2d1641d 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 244 258 3.8E-7 T 13-09-2016 THL1_RS14450 b76a88c6217771c696cad5a4c2d1641d 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 3.8E-7 T 13-09-2016 THL1_RS14450 b76a88c6217771c696cad5a4c2d1641d 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 285 292 3.8E-7 T 13-09-2016 THL1_RS14450 b76a88c6217771c696cad5a4c2d1641d 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 3.8E-7 T 13-09-2016 THL1_RS14450 b76a88c6217771c696cad5a4c2d1641d 400 PANTHER PTHR22912:SF180 64 330 4.6E-23 T 13-09-2016 THL1_RS24565 919049dca546b693c08bdd34ed67788a 107 Gene3D G3DSA:1.10.260.40 33 87 1.0E-8 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS24565 919049dca546b693c08bdd34ed67788a 107 Pfam PF13744 Helix-turn-helix domain 12 86 3.3E-13 T 13-09-2016 THL1_RS24565 919049dca546b693c08bdd34ed67788a 107 SUPERFAMILY SSF47413 28 95 2.79E-12 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS17880 db43ec546d505d225eebcc212424cab6 207 SUPERFAMILY SSF52499 3 207 2.88E-60 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS17880 db43ec546d505d225eebcc212424cab6 207 PRINTS PR01398 Isochorismatase signature 3 15 3.3E-41 T 13-09-2016 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 THL1_RS17880 db43ec546d505d225eebcc212424cab6 207 PRINTS PR01398 Isochorismatase signature 185 202 3.3E-41 T 13-09-2016 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 THL1_RS17880 db43ec546d505d225eebcc212424cab6 207 PRINTS PR01398 Isochorismatase signature 62 79 3.3E-41 T 13-09-2016 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 THL1_RS17880 db43ec546d505d225eebcc212424cab6 207 PRINTS PR01398 Isochorismatase signature 111 133 3.3E-41 T 13-09-2016 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 THL1_RS17880 db43ec546d505d225eebcc212424cab6 207 PRINTS PR01398 Isochorismatase signature 79 98 3.3E-41 T 13-09-2016 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 THL1_RS17880 db43ec546d505d225eebcc212424cab6 207 PRINTS PR01398 Isochorismatase signature 167 185 3.3E-41 T 13-09-2016 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 THL1_RS17880 db43ec546d505d225eebcc212424cab6 207 Pfam PF00857 Isochorismatase family 33 204 4.9E-36 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS17880 db43ec546d505d225eebcc212424cab6 207 PANTHER PTHR11080 7 206 4.2E-96 T 13-09-2016 THL1_RS17880 db43ec546d505d225eebcc212424cab6 207 PANTHER PTHR11080:SF4 7 206 4.2E-96 T 13-09-2016 THL1_RS17880 db43ec546d505d225eebcc212424cab6 207 Gene3D G3DSA:3.40.50.850 4 207 1.7E-57 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS17880 db43ec546d505d225eebcc212424cab6 207 PIRSF PIRSF001111 2 207 2.3E-90 T 13-09-2016 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 THL1_RS04235 2880e6dfffa6db7c272717ebd0ee0868 381 Pfam PF01098 Cell cycle protein 33 376 7.3E-108 T 13-09-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 THL1_RS04235 2880e6dfffa6db7c272717ebd0ee0868 381 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 28 376 1.9E-132 T 13-09-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 THL1_RS04235 2880e6dfffa6db7c272717ebd0ee0868 381 PANTHER PTHR30474:SF1 7 380 3.7E-162 T 13-09-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 THL1_RS04235 2880e6dfffa6db7c272717ebd0ee0868 381 PANTHER PTHR30474 7 380 3.7E-162 T 13-09-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 THL1_RS26525 575ec1188c55b3ebf926784eb40ff3fc 283 PANTHER PTHR30177:SF10 6 283 7.0E-175 T 13-09-2016 THL1_RS26525 575ec1188c55b3ebf926784eb40ff3fc 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 268 1.5E-26 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS26525 575ec1188c55b3ebf926784eb40ff3fc 283 PANTHER PTHR30177 6 283 7.0E-175 T 13-09-2016 THL1_RS26525 575ec1188c55b3ebf926784eb40ff3fc 283 Gene3D G3DSA:1.10.3720.10 86 270 1.5E-40 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS26525 575ec1188c55b3ebf926784eb40ff3fc 283 SUPERFAMILY SSF161098 88 271 7.85E-43 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS10560 741fb4c830b2af634e8b28e6b29e8f96 298 TIGRFAM TIGR03702 lip_kinase_YegS: lipid kinase YegS 5 296 4.7E-131 T 13-09-2016 IPR022433 Lipid kinase YegS GO:0001727|GO:0046872 THL1_RS10560 741fb4c830b2af634e8b28e6b29e8f96 298 PANTHER PTHR12358 28 295 3.6E-43 T 13-09-2016 THL1_RS10560 741fb4c830b2af634e8b28e6b29e8f96 298 Hamap MF_01377 Probable lipid kinase YegS [yegS]. 3 297 45.224 T 13-09-2016 IPR022433 Lipid kinase YegS GO:0001727|GO:0046872 THL1_RS10560 741fb4c830b2af634e8b28e6b29e8f96 298 Pfam PF00781 Diacylglycerol kinase catalytic domain 9 123 1.7E-22 T 13-09-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 THL1_RS10560 741fb4c830b2af634e8b28e6b29e8f96 298 SUPERFAMILY SSF111331 3 291 6.98E-62 T 13-09-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain THL1_RS10560 741fb4c830b2af634e8b28e6b29e8f96 298 SMART SM00046 6 128 2.8E-7 T 13-09-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 THL1_RS10560 741fb4c830b2af634e8b28e6b29e8f96 298 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 7 290 1.8E-55 T 13-09-2016 IPR005218 Diacylglycerol/lipid kinase THL1_RS01845 7c25af395232b8de412d6ab0f42376cb 321 SUPERFAMILY SSF48179 188 275 1.19E-14 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS01845 7c25af395232b8de412d6ab0f42376cb 321 Hamap MF_02129 L-carnitine dehydrogenase [lcdH]. 8 318 54.585 T 13-09-2016 IPR026578 L-carnitine dehydrogenase KEGG: 00040+1.1.1.10|MetaCyc: PWY-3602|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7472|UniPathway: UPA00117 THL1_RS01845 7c25af395232b8de412d6ab0f42376cb 321 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 11 184 3.3E-40 T 13-09-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS01845 7c25af395232b8de412d6ab0f42376cb 321 Gene3D G3DSA:3.40.50.720 3 189 3.6E-42 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS01845 7c25af395232b8de412d6ab0f42376cb 321 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 256 6.5E-15 T 13-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS01845 7c25af395232b8de412d6ab0f42376cb 321 SUPERFAMILY SSF51735 6 185 6.01E-47 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS01845 7c25af395232b8de412d6ab0f42376cb 321 Gene3D G3DSA:1.10.1040.10 190 260 3.7E-9 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS01845 7c25af395232b8de412d6ab0f42376cb 321 PANTHER PTHR23309 5 315 1.3E-104 T 13-09-2016 THL1_RS01845 7c25af395232b8de412d6ab0f42376cb 321 PANTHER PTHR23309:SF17 5 315 1.3E-104 T 13-09-2016 THL1_RS10485 6a80f3ad1d2c115a628b5bc51c518037 96 PANTHER PTHR36154 19 83 6.5E-14 T 13-09-2016 THL1_RS10485 6a80f3ad1d2c115a628b5bc51c518037 96 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 20 69 1.3E-18 T 13-09-2016 IPR010260 Prophage CP4-57 regulatory protein (AlpA) THL1_RS03710 8ed9703854f9095ef7f47b25695c5405 420 SUPERFAMILY SSF56014 80 235 5.23E-19 T 13-09-2016 THL1_RS03710 8ed9703854f9095ef7f47b25695c5405 420 SUPERFAMILY SSF55124 250 313 8.04E-12 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS03710 8ed9703854f9095ef7f47b25695c5405 420 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 8 69 2.6E-12 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS03710 8ed9703854f9095ef7f47b25695c5405 420 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 253 298 3.2E-13 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS03710 8ed9703854f9095ef7f47b25695c5405 420 PANTHER PTHR11493 1 404 2.8E-55 T 13-09-2016 THL1_RS03710 8ed9703854f9095ef7f47b25695c5405 420 SUPERFAMILY SSF55124 6 72 1.62E-13 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS03710 8ed9703854f9095ef7f47b25695c5405 420 Gene3D G3DSA:3.30.413.10 322 401 1.4E-10 T 13-09-2016 THL1_RS03710 8ed9703854f9095ef7f47b25695c5405 420 Gene3D G3DSA:3.30.413.10 80 211 2.0E-8 T 13-09-2016 THL1_RS03710 8ed9703854f9095ef7f47b25695c5405 420 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 79 210 1.7E-9 T 13-09-2016 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS03710 8ed9703854f9095ef7f47b25695c5405 420 SUPERFAMILY SSF56014 322 411 1.01E-14 T 13-09-2016 THL1_RS03710 8ed9703854f9095ef7f47b25695c5405 420 Gene3D G3DSA:3.90.480.10 7 76 3.6E-26 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS03710 8ed9703854f9095ef7f47b25695c5405 420 Gene3D G3DSA:3.90.480.10 242 313 3.6E-26 T 13-09-2016 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683|UniPathway: UPA00140 THL1_RS03710 8ed9703854f9095ef7f47b25695c5405 420 TIGRFAM TIGR02435 CobG: precorrin-3B synthase 1 381 1.6E-103 T 13-09-2016 IPR012798 Cobalamin (vitamin B12) biosynthesis CobG-like THL1_RS24020 e2ab12aa9904682fded82cd787954793 194 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 5 191 1.1E-63 T 13-09-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 THL1_RS24020 e2ab12aa9904682fded82cd787954793 194 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 4 183 35.339 T 13-09-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 THL1_RS24020 e2ab12aa9904682fded82cd787954793 194 Pfam PF01195 Peptidyl-tRNA hydrolase 6 188 2.4E-52 T 13-09-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 THL1_RS24020 e2ab12aa9904682fded82cd787954793 194 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 17 30 - T 13-09-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 THL1_RS24020 e2ab12aa9904682fded82cd787954793 194 PANTHER PTHR17224 6 194 4.5E-79 T 13-09-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 THL1_RS24020 e2ab12aa9904682fded82cd787954793 194 SUPERFAMILY SSF53178 4 191 3.14E-68 T 13-09-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 THL1_RS24020 e2ab12aa9904682fded82cd787954793 194 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 111 121 - T 13-09-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 THL1_RS24020 e2ab12aa9904682fded82cd787954793 194 Gene3D G3DSA:3.40.50.1470 5 192 2.1E-68 T 13-09-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 THL1_RS08890 59fdee519439c1e4f649e9cd205e1c99 415 PIRSF PIRSF000355 64 415 2.8E-142 T 13-09-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 THL1_RS08890 59fdee519439c1e4f649e9cd205e1c99 415 Gene3D G3DSA:1.10.620.20 85 389 1.6E-109 T 13-09-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: REACT_1698 THL1_RS08890 59fdee519439c1e4f649e9cd205e1c99 415 SUPERFAMILY SSF47240 59 388 7.08E-98 T 13-09-2016 IPR009078 Ferritin-like superfamily THL1_RS08890 59fdee519439c1e4f649e9cd205e1c99 415 PANTHER PTHR23409 18 410 4.1E-198 T 13-09-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 THL1_RS08890 59fdee519439c1e4f649e9cd205e1c99 415 Pfam PF00268 Ribonucleotide reductase, small chain 95 382 2.4E-83 T 13-09-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 THL1_RS08890 59fdee519439c1e4f649e9cd205e1c99 415 PANTHER PTHR23409:SF18 18 410 4.1E-198 T 13-09-2016 THL1_RS01100 7f975a08779d22ce53c9febbfd103435 234 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 218 9.9E-20 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01100 7f975a08779d22ce53c9febbfd103435 234 SUPERFAMILY SSF161098 21 215 1.83E-38 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS01100 7f975a08779d22ce53c9febbfd103435 234 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 21 125 5.6E-21 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS01100 7f975a08779d22ce53c9febbfd103435 234 PANTHER PTHR30614 1 234 8.4E-65 T 13-09-2016 THL1_RS01100 7f975a08779d22ce53c9febbfd103435 234 Gene3D G3DSA:1.10.3720.10 20 221 3.7E-41 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS27925 2e7e4ce9e29dec15be6a52da3f64c06d 141 TIGRFAM TIGR02803 ExbD_1: TonB system transport protein ExbD 15 136 3.6E-63 T 13-09-2016 IPR014170 TonB system transport protein ExbD type-1 GO:0006810|GO:0016020 THL1_RS27925 2e7e4ce9e29dec15be6a52da3f64c06d 141 Pfam PF02472 Biopolymer transport protein ExbD/TolR 14 133 4.5E-31 T 13-09-2016 IPR003400 Biopolymer transport protein ExbD/TolR GO:0005215|GO:0006810|GO:0016020 THL1_RS27925 2e7e4ce9e29dec15be6a52da3f64c06d 141 PANTHER PTHR30558:SF9 11 140 2.8E-66 T 13-09-2016 THL1_RS27925 2e7e4ce9e29dec15be6a52da3f64c06d 141 PANTHER PTHR30558 11 140 2.8E-66 T 13-09-2016 THL1_RS27925 2e7e4ce9e29dec15be6a52da3f64c06d 141 TIGRFAM TIGR02801 tolR: protein TolR 16 133 9.8E-38 T 13-09-2016 IPR014168 Biopolymer transport, TolR GO:0015031|GO:0016021 THL1_RS14230 f1a36c14623b89eaa93fcc51b466f340 248 Gene3D G3DSA:2.60.40.10 168 247 2.4E-9 T 13-09-2016 IPR013783 Immunoglobulin-like fold THL1_RS14230 f1a36c14623b89eaa93fcc51b466f340 248 TIGRFAM TIGR04557 fuse_rel_SoxYZ: quinoprotein dehydrogenase-associated SoxYZ-like carrier 30 245 2.4E-60 T 13-09-2016 IPR030831 Quinoprotein dehydrogenase-associated SoxYZ-like carrier THL1_RS14230 f1a36c14623b89eaa93fcc51b466f340 248 Pfam PF08770 Sulphur oxidation protein SoxZ 168 247 7.6E-8 T 13-09-2016 IPR014880 Sulphur oxidation protein SoxZ THL1_RS14230 f1a36c14623b89eaa93fcc51b466f340 248 Pfam PF13501 Sulfur oxidation protein SoxY 35 141 3.4E-25 T 13-09-2016 IPR032711 Ig-like SoxY domain THL1_RS14230 f1a36c14623b89eaa93fcc51b466f340 248 SUPERFAMILY SSF81296 164 247 8.12E-14 T 13-09-2016 IPR014756 Immunoglobulin E-set THL1_RS12190 c83edcc82ca9abc2b617c4969a226a3e 624 Gene3D G3DSA:1.10.760.10 567 601 1.4E-9 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS12190 c83edcc82ca9abc2b617c4969a226a3e 624 Gene3D G3DSA:1.10.760.10 457 458 1.4E-9 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS12190 c83edcc82ca9abc2b617c4969a226a3e 624 Gene3D G3DSA:1.10.760.10 356 372 1.4E-9 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS12190 c83edcc82ca9abc2b617c4969a226a3e 624 Gene3D G3DSA:1.10.760.10 407 412 1.4E-9 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS12190 c83edcc82ca9abc2b617c4969a226a3e 624 Gene3D G3DSA:1.10.760.10 491 527 1.4E-9 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS12190 c83edcc82ca9abc2b617c4969a226a3e 624 SUPERFAMILY SSF46626 577 601 2.57E-16 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS12190 c83edcc82ca9abc2b617c4969a226a3e 624 SUPERFAMILY SSF46626 351 410 2.57E-16 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS12190 c83edcc82ca9abc2b617c4969a226a3e 624 SUPERFAMILY SSF46626 481 525 2.57E-16 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS09150 15c20e990b3cfeff9df4aa0e1b62b001 231 PANTHER PTHR11019:SF97 1 63 1.4E-64 T 13-09-2016 THL1_RS09150 15c20e990b3cfeff9df4aa0e1b62b001 231 PANTHER PTHR11019 1 63 1.4E-64 T 13-09-2016 THL1_RS09150 15c20e990b3cfeff9df4aa0e1b62b001 231 PANTHER PTHR11019 84 223 1.4E-64 T 13-09-2016 THL1_RS09150 15c20e990b3cfeff9df4aa0e1b62b001 231 PANTHER PTHR11019:SF97 84 223 1.4E-64 T 13-09-2016 THL1_RS09150 15c20e990b3cfeff9df4aa0e1b62b001 231 SUPERFAMILY SSF52317 1 224 3.0E-76 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS09150 15c20e990b3cfeff9df4aa0e1b62b001 231 Gene3D G3DSA:3.40.50.880 1 227 4.8E-92 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS09150 15c20e990b3cfeff9df4aa0e1b62b001 231 Pfam PF01965 DJ-1/PfpI family 25 222 2.0E-15 T 13-09-2016 IPR002818 DJ-1/PfpI THL1_RS00085 e947ea1912ea8bac9be91c7c72525719 103 SMART SM00028 16 49 0.061 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS00085 e947ea1912ea8bac9be91c7c72525719 103 SMART SM00028 50 83 0.013 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS00085 e947ea1912ea8bac9be91c7c72525719 103 Pfam PF13432 Tetratricopeptide repeat 21 78 6.1E-9 T 13-09-2016 THL1_RS00085 e947ea1912ea8bac9be91c7c72525719 103 Gene3D G3DSA:1.25.40.10 5 83 2.1E-15 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS00085 e947ea1912ea8bac9be91c7c72525719 103 SUPERFAMILY SSF48452 5 99 4.61E-14 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS06240 ec1dd5d3650290087f9b4eaa32398ede 181 SUPERFAMILY SSF55729 2 156 5.8E-29 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS06240 ec1dd5d3650290087f9b4eaa32398ede 181 Pfam PF00583 Acetyltransferase (GNAT) family 76 152 6.6E-20 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS06240 ec1dd5d3650290087f9b4eaa32398ede 181 PANTHER PTHR23091 40 155 7.1E-21 T 13-09-2016 THL1_RS06240 ec1dd5d3650290087f9b4eaa32398ede 181 Gene3D G3DSA:3.40.630.30 1 156 4.4E-30 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS06360 548b339ed1d5d6ed69783a9cb8ca19bd 365 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 173 358 5.9E-23 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS06360 548b339ed1d5d6ed69783a9cb8ca19bd 365 PANTHER PTHR30085:SF3 63 365 1.7E-161 T 13-09-2016 THL1_RS06360 548b339ed1d5d6ed69783a9cb8ca19bd 365 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 155 251 8.1E-20 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS06360 548b339ed1d5d6ed69783a9cb8ca19bd 365 SUPERFAMILY SSF161098 154 345 1.7E-38 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS06360 548b339ed1d5d6ed69783a9cb8ca19bd 365 Gene3D G3DSA:1.10.3720.10 154 360 6.8E-43 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS06360 548b339ed1d5d6ed69783a9cb8ca19bd 365 PANTHER PTHR30085 63 365 1.7E-161 T 13-09-2016 THL1_RS15945 c68f5f5039dbe6d2cf2221071ce87d0f 92 Pfam PF00639 PPIC-type PPIASE domain 12 88 3.9E-20 T 13-09-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 THL1_RS15945 c68f5f5039dbe6d2cf2221071ce87d0f 92 Gene3D G3DSA:3.10.50.40 4 88 2.7E-31 T 13-09-2016 THL1_RS15945 c68f5f5039dbe6d2cf2221071ce87d0f 92 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 30 50 - T 13-09-2016 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site THL1_RS15945 c68f5f5039dbe6d2cf2221071ce87d0f 92 PANTHER PTHR10657 6 88 1.2E-32 T 13-09-2016 THL1_RS15945 c68f5f5039dbe6d2cf2221071ce87d0f 92 SUPERFAMILY SSF54534 3 88 6.54E-28 T 13-09-2016 THL1_RS27360 5506e8a8b05a612d827ebbd741037687 150 PANTHER PTHR35146:SF1 1 149 9.9E-46 T 13-09-2016 THL1_RS27360 5506e8a8b05a612d827ebbd741037687 150 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 32.454 T 13-09-2016 IPR003791 Protein of unknown function UPF0178 THL1_RS27360 5506e8a8b05a612d827ebbd741037687 150 PANTHER PTHR35146 1 149 9.9E-46 T 13-09-2016 THL1_RS27360 5506e8a8b05a612d827ebbd741037687 150 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 18 146 1.0E-40 T 13-09-2016 IPR003791 Protein of unknown function UPF0178 THL1_RS17470 da4c20ff227f2413ac9328b9cdf3ad3b 260 Gene3D G3DSA:1.10.12.10 200 250 3.9E-19 T 13-09-2016 IPR014748 Crontonase, C-terminal THL1_RS17470 da4c20ff227f2413ac9328b9cdf3ad3b 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 256 4.3E-72 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS17470 da4c20ff227f2413ac9328b9cdf3ad3b 260 SUPERFAMILY SSF52096 1 257 1.9E-78 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS17470 da4c20ff227f2413ac9328b9cdf3ad3b 260 TIGRFAM TIGR03210 badI: 2-ketocyclohexanecarboxyl-CoA hydrolase 3 258 4.2E-143 T 13-09-2016 IPR017623 2-ketocyclohexanecarboxyl-CoA hydrolase THL1_RS17470 da4c20ff227f2413ac9328b9cdf3ad3b 260 PANTHER PTHR11941 2 255 1.1E-129 T 13-09-2016 THL1_RS17470 da4c20ff227f2413ac9328b9cdf3ad3b 260 PANTHER PTHR11941:SF20 2 255 1.1E-129 T 13-09-2016 THL1_RS17470 da4c20ff227f2413ac9328b9cdf3ad3b 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 100 120 - T 13-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THL1_RS17470 da4c20ff227f2413ac9328b9cdf3ad3b 260 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 1 260 46.741 T 13-09-2016 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837|UniPathway: UPA00079|UniPathway: UPA01057 THL1_RS17470 da4c20ff227f2413ac9328b9cdf3ad3b 260 Gene3D G3DSA:3.90.226.10 1 198 5.1E-65 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS07665 7c3e74f35bf2e076f57c6760e84932d8 96 TIGRFAM TIGR03221 muco_delta: muconolactone delta-isomerase 2 91 1.5E-46 T 13-09-2016 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185|UniPathway: UPA00157 THL1_RS07665 7c3e74f35bf2e076f57c6760e84932d8 96 Pfam PF02426 Muconolactone delta-isomerase 1 90 6.2E-39 T 13-09-2016 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185|UniPathway: UPA00157 THL1_RS07665 7c3e74f35bf2e076f57c6760e84932d8 96 ProDom PD006619 ISOMERASE MUCONOLACTONE DELTA-ISOMERASE HYDROCARBONS MIASE AROMATIC CATABOLISM METHYLMUCONOLACTONE DIRECT SEQUENCING 1 57 4.0E-27 T 13-09-2016 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185|UniPathway: UPA00157 THL1_RS07665 7c3e74f35bf2e076f57c6760e84932d8 96 PIRSF PIRSF001486 1 94 2.8E-45 T 13-09-2016 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185|UniPathway: UPA00157 THL1_RS07665 7c3e74f35bf2e076f57c6760e84932d8 96 SUPERFAMILY SSF54909 1 95 2.36E-37 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS20050 1079173f4c048916bf24f6a5ae071740 220 SUPERFAMILY SSF52172 1 166 4.68E-38 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS20050 1079173f4c048916bf24f6a5ae071740 220 Gene3D G3DSA:1.10.10.10 126 216 4.0E-30 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS20050 1079173f4c048916bf24f6a5ae071740 220 SMART SM00448 1 112 9.6E-40 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS20050 1079173f4c048916bf24f6a5ae071740 220 PANTHER PTHR26402:SF279 1 216 1.9E-101 T 13-09-2016 THL1_RS20050 1079173f4c048916bf24f6a5ae071740 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 215 3.3E-24 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS20050 1079173f4c048916bf24f6a5ae071740 220 Gene3D G3DSA:3.40.50.2300 1 121 2.5E-38 T 13-09-2016 THL1_RS20050 1079173f4c048916bf24f6a5ae071740 220 SMART SM00862 145 216 4.6E-26 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS20050 1079173f4c048916bf24f6a5ae071740 220 PANTHER PTHR26402 1 216 1.9E-101 T 13-09-2016 THL1_RS20050 1079173f4c048916bf24f6a5ae071740 220 Pfam PF00072 Response regulator receiver domain 4 112 1.6E-27 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS18390 13d126a8eb7b8bfcd0bc9b1d8fae6998 538 Gene3D G3DSA:3.90.226.10 278 526 4.1E-73 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS18390 13d126a8eb7b8bfcd0bc9b1d8fae6998 538 Gene3D G3DSA:3.90.226.10 40 270 2.2E-54 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS18390 13d126a8eb7b8bfcd0bc9b1d8fae6998 538 PANTHER PTHR22855 1 538 0.0 T 13-09-2016 THL1_RS18390 13d126a8eb7b8bfcd0bc9b1d8fae6998 538 SUPERFAMILY SSF52096 34 269 8.09E-59 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS18390 13d126a8eb7b8bfcd0bc9b1d8fae6998 538 PANTHER PTHR22855:SF29 1 538 0.0 T 13-09-2016 THL1_RS18390 13d126a8eb7b8bfcd0bc9b1d8fae6998 538 SUPERFAMILY SSF52096 278 535 1.13E-76 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS18390 13d126a8eb7b8bfcd0bc9b1d8fae6998 538 Pfam PF01039 Carboxyl transferase domain 49 514 4.9E-120 T 13-09-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS20075 edf9023a929e1cd4605a2acb3c8691eb 91 Pfam PF02583 Metal-sensitive transcriptional repressor 8 87 5.0E-21 T 13-09-2016 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 THL1_RS20075 edf9023a929e1cd4605a2acb3c8691eb 91 PANTHER PTHR33677 1 91 3.5E-27 T 13-09-2016 THL1_RS10365 e172f7886752bd2e39e6b8842b13bb5c 485 Gene3D G3DSA:3.40.710.10 243 477 4.2E-64 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS10365 e172f7886752bd2e39e6b8842b13bb5c 485 PANTHER PTHR30023 17 481 3.4E-87 T 13-09-2016 THL1_RS10365 e172f7886752bd2e39e6b8842b13bb5c 485 SUPERFAMILY SSF56601 28 479 9.26E-88 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS10365 e172f7886752bd2e39e6b8842b13bb5c 485 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 372 386 3.2E-22 T 13-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THL1_RS10365 e172f7886752bd2e39e6b8842b13bb5c 485 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 70 89 3.2E-22 T 13-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THL1_RS10365 e172f7886752bd2e39e6b8842b13bb5c 485 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 297 319 3.2E-22 T 13-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THL1_RS10365 e172f7886752bd2e39e6b8842b13bb5c 485 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 434 447 3.2E-22 T 13-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THL1_RS10365 e172f7886752bd2e39e6b8842b13bb5c 485 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 357 371 3.2E-22 T 13-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THL1_RS10365 e172f7886752bd2e39e6b8842b13bb5c 485 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 65 457 7.8E-63 T 13-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THL1_RS10365 e172f7886752bd2e39e6b8842b13bb5c 485 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 64 457 7.0E-82 T 13-09-2016 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THL1_RS10365 e172f7886752bd2e39e6b8842b13bb5c 485 PANTHER PTHR30023:SF0 17 481 3.4E-87 T 13-09-2016 THL1_RS14355 44dc75f011c3e46b9760debe02e560fa 239 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 81 109 - T 13-09-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 THL1_RS14355 44dc75f011c3e46b9760debe02e560fa 239 PANTHER PTHR33711:SF1 8 239 9.5E-132 T 13-09-2016 THL1_RS14355 44dc75f011c3e46b9760debe02e560fa 239 Pfam PF00775 Dioxygenase 49 230 6.3E-60 T 13-09-2016 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 THL1_RS14355 44dc75f011c3e46b9760debe02e560fa 239 Gene3D G3DSA:2.60.130.10 10 238 6.7E-79 T 13-09-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 THL1_RS14355 44dc75f011c3e46b9760debe02e560fa 239 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 17 238 5.2E-110 T 13-09-2016 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|UniPathway: UPA00157 THL1_RS14355 44dc75f011c3e46b9760debe02e560fa 239 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 12 43 5.4E-15 T 13-09-2016 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3|UniPathway: UPA00157 THL1_RS14355 44dc75f011c3e46b9760debe02e560fa 239 SUPERFAMILY SSF49482 11 238 7.72E-75 T 13-09-2016 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 THL1_RS14355 44dc75f011c3e46b9760debe02e560fa 239 PANTHER PTHR33711 8 239 9.5E-132 T 13-09-2016 THL1_RS24995 1ce9661108f7d34baef972acbd2cdde9 631 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 34 578 5.6E-157 T 13-09-2016 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 THL1_RS24995 1ce9661108f7d34baef972acbd2cdde9 631 Pfam PF03958 Bacterial type II/III secretion system short domain 258 332 6.4E-11 T 13-09-2016 IPR005644 NolW-like THL1_RS24995 1ce9661108f7d34baef972acbd2cdde9 631 Pfam PF03958 Bacterial type II/III secretion system short domain 123 180 4.7E-9 T 13-09-2016 IPR005644 NolW-like THL1_RS24995 1ce9661108f7d34baef972acbd2cdde9 631 Pfam PF03958 Bacterial type II/III secretion system short domain 188 251 6.7E-11 T 13-09-2016 IPR005644 NolW-like THL1_RS24995 1ce9661108f7d34baef972acbd2cdde9 631 PANTHER PTHR30332:SF3 23 604 4.2E-183 T 13-09-2016 THL1_RS24995 1ce9661108f7d34baef972acbd2cdde9 631 Pfam PF00263 Bacterial type II and III secretion system protein 407 573 3.5E-52 T 13-09-2016 IPR004846 Type II/III secretion system GO:0009306 THL1_RS24995 1ce9661108f7d34baef972acbd2cdde9 631 PRINTS PR00811 Bacterial general secretion pathway protein D signature 561 575 9.3E-40 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS24995 1ce9661108f7d34baef972acbd2cdde9 631 PRINTS PR00811 Bacterial general secretion pathway protein D signature 403 427 9.3E-40 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS24995 1ce9661108f7d34baef972acbd2cdde9 631 PRINTS PR00811 Bacterial general secretion pathway protein D signature 332 342 9.3E-40 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS24995 1ce9661108f7d34baef972acbd2cdde9 631 PRINTS PR00811 Bacterial general secretion pathway protein D signature 538 556 9.3E-40 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS24995 1ce9661108f7d34baef972acbd2cdde9 631 PRINTS PR00811 Bacterial general secretion pathway protein D signature 438 448 9.3E-40 T 13-09-2016 IPR001775 GspD/PilQ family THL1_RS24995 1ce9661108f7d34baef972acbd2cdde9 631 PANTHER PTHR30332 23 604 4.2E-183 T 13-09-2016 THL1_RS02850 99f2911d1d8c39c6653514125e3c42cc 326 PANTHER PTHR35604:SF2 3 324 9.5E-176 T 13-09-2016 THL1_RS02850 99f2911d1d8c39c6653514125e3c42cc 326 Pfam PF01609 Transposase DDE domain 135 310 1.4E-32 T 13-09-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THL1_RS02850 99f2911d1d8c39c6653514125e3c42cc 326 PANTHER PTHR35604 3 324 9.5E-176 T 13-09-2016 THL1_RS02850 99f2911d1d8c39c6653514125e3c42cc 326 Pfam PF05598 Transposase domain (DUF772) 50 115 2.3E-18 T 13-09-2016 IPR008490 Transposase InsH, N-terminal THL1_RS18740 c5438dfa42b03d8d087d268488d8bcb1 514 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 46 205 1.9E-22 T 13-09-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 THL1_RS18740 c5438dfa42b03d8d087d268488d8bcb1 514 SUPERFAMILY SSF53474 20 350 3.02E-38 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS18740 c5438dfa42b03d8d087d268488d8bcb1 514 Gene3D G3DSA:3.40.50.1820 37 309 6.9E-38 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS07870 da18454b2ce796e4e45eace85aea8d2d 425 Gene3D G3DSA:3.40.640.10 16 264 2.4E-88 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS07870 da18454b2ce796e4e45eace85aea8d2d 425 Gene3D G3DSA:3.90.1150.10 265 400 3.2E-41 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS07870 da18454b2ce796e4e45eace85aea8d2d 425 PIRSF PIRSF001434 1 401 9.1E-144 T 13-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 THL1_RS07870 da18454b2ce796e4e45eace85aea8d2d 425 SUPERFAMILY SSF53383 30 397 2.58E-108 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS07870 da18454b2ce796e4e45eace85aea8d2d 425 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 208 222 - T 13-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 THL1_RS07870 da18454b2ce796e4e45eace85aea8d2d 425 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 17 397 2.2E-128 T 13-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 THL1_RS07870 da18454b2ce796e4e45eace85aea8d2d 425 PANTHER PTHR11808 14 402 1.2E-157 T 13-09-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 THL1_RS22990 a4ef218933d3797c9cee669837fafe5d 146 Pfam PF07885 Ion channel 67 132 7.1E-10 T 13-09-2016 IPR013099 Potassium channel domain THL1_RS22990 a4ef218933d3797c9cee669837fafe5d 146 SUPERFAMILY SSF81324 45 141 8.63E-13 T 13-09-2016 THL1_RS22990 a4ef218933d3797c9cee669837fafe5d 146 Gene3D G3DSA:1.10.287.70 53 132 7.9E-9 T 13-09-2016 THL1_RS23450 1f6ffaf0386edeb08aa576a02df18735 135 PIRSF PIRSF029543 1 135 5.4E-41 T 13-09-2016 IPR016924 Uncharacterised conserved protein UCP029543 THL1_RS23450 1f6ffaf0386edeb08aa576a02df18735 135 Gene3D G3DSA:1.10.10.690 46 88 8.3E-5 T 13-09-2016 IPR027405 YidB-like THL1_RS19655 5723597f4975f5ace735884eb5e68bad 121 SUPERFAMILY SSF160214 18 120 1.83E-23 T 13-09-2016 IPR005186 FlaG protein THL1_RS19655 5723597f4975f5ace735884eb5e68bad 121 PANTHER PTHR37166:SF1 52 121 3.0E-19 T 13-09-2016 THL1_RS19655 5723597f4975f5ace735884eb5e68bad 121 Pfam PF03646 FlaG protein 35 118 1.8E-23 T 13-09-2016 IPR005186 FlaG protein THL1_RS19655 5723597f4975f5ace735884eb5e68bad 121 PANTHER PTHR37166 52 121 3.0E-19 T 13-09-2016 THL1_RS19655 5723597f4975f5ace735884eb5e68bad 121 Gene3D G3DSA:3.30.160.170 39 117 2.0E-23 T 13-09-2016 IPR005186 FlaG protein THL1_RS06365 75058fa947d97a722755b3f559de1b37 395 PANTHER PTHR30085:SF1 253 395 3.3E-158 T 13-09-2016 THL1_RS06365 75058fa947d97a722755b3f559de1b37 395 PANTHER PTHR30085 253 395 3.3E-158 T 13-09-2016 THL1_RS06365 75058fa947d97a722755b3f559de1b37 395 SUPERFAMILY SSF161098 86 201 1.96E-12 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS06365 75058fa947d97a722755b3f559de1b37 395 Gene3D G3DSA:1.10.3720.10 85 155 3.0E-44 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS06365 75058fa947d97a722755b3f559de1b37 395 Gene3D G3DSA:1.10.3720.10 261 390 3.0E-44 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS06365 75058fa947d97a722755b3f559de1b37 395 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 86 149 1.9E-15 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS06365 75058fa947d97a722755b3f559de1b37 395 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 390 7.5E-14 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS06365 75058fa947d97a722755b3f559de1b37 395 PANTHER PTHR30085:SF1 4 174 3.3E-158 T 13-09-2016 THL1_RS06365 75058fa947d97a722755b3f559de1b37 395 SUPERFAMILY SSF161098 179 376 4.45E-24 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS06365 75058fa947d97a722755b3f559de1b37 395 PANTHER PTHR30085 4 174 3.3E-158 T 13-09-2016 THL1_RS01010 3d52fc2871fcb5f2360540673560c3bf 260 Pfam PF01925 Sulfite exporter TauE/SafE 7 257 3.5E-53 T 13-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 THL1_RS01010 3d52fc2871fcb5f2360540673560c3bf 260 PANTHER PTHR30269 1 260 9.5E-104 T 13-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 THL1_RS01010 3d52fc2871fcb5f2360540673560c3bf 260 PANTHER PTHR30269:SF18 1 260 9.5E-104 T 13-09-2016 THL1_RS21665 ccdb420141e771da1e56b318f4ef3044 501 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 27 461 4.3E-32 T 13-09-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 THL1_RS21665 ccdb420141e771da1e56b318f4ef3044 501 PIRSF PIRSF002744 1 483 4.4E-92 T 13-09-2016 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 THL1_RS21665 ccdb420141e771da1e56b318f4ef3044 501 PANTHER PTHR31806 19 487 2.8E-72 T 13-09-2016 THL1_RS22300 6ef9255299e7aad506a8a00700309faf 303 Gene3D G3DSA:3.40.50.1100 44 142 2.9E-37 T 13-09-2016 THL1_RS22300 6ef9255299e7aad506a8a00700309faf 303 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 296 1.1E-123 T 13-09-2016 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 THL1_RS22300 6ef9255299e7aad506a8a00700309faf 303 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 285 1.3E-66 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS22300 6ef9255299e7aad506a8a00700309faf 303 TIGRFAM TIGR01138 cysM: cysteine synthase B 7 296 3.4E-162 T 13-09-2016 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 THL1_RS22300 6ef9255299e7aad506a8a00700309faf 303 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 13-09-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 THL1_RS22300 6ef9255299e7aad506a8a00700309faf 303 PANTHER PTHR10314:SF100 1 298 3.7E-186 T 13-09-2016 THL1_RS22300 6ef9255299e7aad506a8a00700309faf 303 Gene3D G3DSA:3.40.50.1100 4 43 2.4E-81 T 13-09-2016 THL1_RS22300 6ef9255299e7aad506a8a00700309faf 303 Gene3D G3DSA:3.40.50.1100 150 297 2.4E-81 T 13-09-2016 THL1_RS22300 6ef9255299e7aad506a8a00700309faf 303 PANTHER PTHR10314 1 298 3.7E-186 T 13-09-2016 THL1_RS22300 6ef9255299e7aad506a8a00700309faf 303 SUPERFAMILY SSF53686 5 293 1.17E-87 T 13-09-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme THL1_RS27885 e7c6f8b65ba3ef857e65d0552a6a2db1 87 Pfam PF01192 RNA polymerase Rpb6 8 60 8.7E-17 T 13-09-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS27885 e7c6f8b65ba3ef857e65d0552a6a2db1 87 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 59 1.5E-22 T 13-09-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS27885 e7c6f8b65ba3ef857e65d0552a6a2db1 87 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 17.713 T 13-09-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS27885 e7c6f8b65ba3ef857e65d0552a6a2db1 87 Gene3D G3DSA:3.90.940.10 1 68 2.5E-17 T 13-09-2016 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS27885 e7c6f8b65ba3ef857e65d0552a6a2db1 87 PANTHER PTHR34476 2 87 2.5E-25 T 13-09-2016 THL1_RS27885 e7c6f8b65ba3ef857e65d0552a6a2db1 87 SMART SM01409 8 61 8.3E-18 T 13-09-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS27885 e7c6f8b65ba3ef857e65d0552a6a2db1 87 SUPERFAMILY SSF63562 1 80 7.5E-26 T 13-09-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THL1_RS06980 8acdf70ca7ad0736597fa91171d50d33 203 Gene3D G3DSA:1.10.472.60 57 162 9.4E-44 T 13-09-2016 IPR023169 UPF0413, central domain THL1_RS06980 8acdf70ca7ad0736597fa91171d50d33 203 Pfam PF01323 DSBA-like thioredoxin domain 2 191 1.1E-14 T 13-09-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 THL1_RS06980 8acdf70ca7ad0736597fa91171d50d33 203 Gene3D G3DSA:3.40.30.10 1 56 8.0E-23 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS06980 8acdf70ca7ad0736597fa91171d50d33 203 SUPERFAMILY SSF52833 1 199 1.91E-36 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS05440 33204e910bd403db9797d2823816ba81 350 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 207 216 - T 13-09-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 THL1_RS05440 33204e910bd403db9797d2823816ba81 350 Pfam PF00155 Aminotransferase class I and II 25 347 5.1E-57 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS05440 33204e910bd403db9797d2823816ba81 350 PANTHER PTHR11751 3 350 5.1E-124 T 13-09-2016 THL1_RS05440 33204e910bd403db9797d2823816ba81 350 PANTHER PTHR11751:SF398 3 350 5.1E-124 T 13-09-2016 THL1_RS05440 33204e910bd403db9797d2823816ba81 350 SUPERFAMILY SSF53383 5 349 1.79E-79 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS05440 33204e910bd403db9797d2823816ba81 350 Gene3D G3DSA:3.40.640.10 38 252 1.5E-63 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS05440 33204e910bd403db9797d2823816ba81 350 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 8 349 4.7E-95 T 13-09-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 THL1_RS05440 33204e910bd403db9797d2823816ba81 350 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 350 56.939 T 13-09-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 THL1_RS05440 33204e910bd403db9797d2823816ba81 350 Gene3D G3DSA:3.90.1150.10 253 350 1.3E-26 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS16410 de541a45f80189e275de93507a7dd6ac 383 Pfam PF11795 Uncharacterized protein conserved in bacteria N-term (DUF3322) 10 187 2.4E-29 T 13-09-2016 IPR024537 Domain of unknown function DUF3322 THL1_RS16410 de541a45f80189e275de93507a7dd6ac 383 Pfam PF09983 Uncharacterized protein conserved in bacteria C-term(DUF2220) 209 375 4.7E-37 T 13-09-2016 IPR024534 Domain of unknown function DUF2220 THL1_RS16410 de541a45f80189e275de93507a7dd6ac 383 PIRSF PIRSF028408 1 383 8.2E-94 T 13-09-2016 IPR014544 Uncharacterised conserved protein UCP028408 THL1_RS04595 ca8459fadc5a822da25c28838fd6c7ff 290 PANTHER PTHR30168 2 290 3.7E-130 T 13-09-2016 THL1_RS04595 ca8459fadc5a822da25c28838fd6c7ff 290 Pfam PF04228 Putative neutral zinc metallopeptidase 1 285 1.2E-118 T 13-09-2016 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative THL1_RS10490 8484030218212369b79702061ed1e049 82 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 16 71 2.5E-13 T 13-09-2016 IPR010260 Prophage CP4-57 regulatory protein (AlpA) THL1_RS24265 8e2dae065e7deffa1ea0345f07f2866a 235 PANTHER PTHR30545:SF2 1 235 5.8E-84 T 13-09-2016 THL1_RS24265 8e2dae065e7deffa1ea0345f07f2866a 235 Pfam PF03749 Sugar fermentation stimulation protein 13 226 7.4E-73 T 13-09-2016 IPR005224 Sugar fermentation stimulation protein THL1_RS24265 8e2dae065e7deffa1ea0345f07f2866a 235 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 4 231 5.4E-63 T 13-09-2016 IPR005224 Sugar fermentation stimulation protein THL1_RS24265 8e2dae065e7deffa1ea0345f07f2866a 235 PANTHER PTHR30545 1 235 5.8E-84 T 13-09-2016 THL1_RS24265 8e2dae065e7deffa1ea0345f07f2866a 235 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 1 235 55.37 T 13-09-2016 IPR005224 Sugar fermentation stimulation protein THL1_RS06820 e0e0c76323b8e47d4f0cacc70b77b762 516 PANTHER PTHR16631:SF5 17 321 9.2E-79 T 13-09-2016 THL1_RS06820 e0e0c76323b8e47d4f0cacc70b77b762 516 PANTHER PTHR16631 17 321 9.2E-79 T 13-09-2016 THL1_RS06820 e0e0c76323b8e47d4f0cacc70b77b762 516 Gene3D G3DSA:3.20.20.80 69 308 2.6E-26 T 13-09-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 THL1_RS06820 e0e0c76323b8e47d4f0cacc70b77b762 516 SUPERFAMILY SSF51445 41 308 3.3E-53 T 13-09-2016 IPR017853 Glycoside hydrolase superfamily THL1_RS20970 fefebdc4924c9fee5f552e7a28532e22 298 Pfam PF00487 Fatty acid desaturase 59 285 2.0E-28 T 13-09-2016 IPR005804 Fatty acid desaturase domain GO:0006629 THL1_RS18400 f1eadd0beb63868a956c94d926391878 264 Gene3D G3DSA:1.10.12.10 208 262 3.9E-11 T 13-09-2016 IPR014748 Crontonase, C-terminal THL1_RS18400 f1eadd0beb63868a956c94d926391878 264 SUPERFAMILY SSF52096 4 263 4.33E-67 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS18400 f1eadd0beb63868a956c94d926391878 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 264 1.5E-48 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS18400 f1eadd0beb63868a956c94d926391878 264 PANTHER PTHR11941:SF86 1 262 1.2E-92 T 13-09-2016 THL1_RS18400 f1eadd0beb63868a956c94d926391878 264 Gene3D G3DSA:3.90.226.10 7 198 3.6E-54 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS18400 f1eadd0beb63868a956c94d926391878 264 PANTHER PTHR11941 1 262 1.2E-92 T 13-09-2016 THL1_RS11300 97367494d9c1f68fb6e76beaf5360ba6 312 Gene3D G3DSA:1.10.3720.10 23 300 2.0E-40 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS11300 97367494d9c1f68fb6e76beaf5360ba6 312 PANTHER PTHR30193:SF5 1 306 1.2E-94 T 13-09-2016 THL1_RS11300 97367494d9c1f68fb6e76beaf5360ba6 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 305 3.0E-12 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS11300 97367494d9c1f68fb6e76beaf5360ba6 312 PANTHER PTHR30193 1 306 1.2E-94 T 13-09-2016 THL1_RS11300 97367494d9c1f68fb6e76beaf5360ba6 312 SUPERFAMILY SSF161098 29 306 1.7E-42 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS13280 1cc5598d366b99b1d9a81ac98759e5c7 151 PANTHER PTHR11527:SF118 11 151 6.2E-26 T 13-09-2016 THL1_RS13280 1cc5598d366b99b1d9a81ac98759e5c7 151 SUPERFAMILY SSF49764 32 150 4.19E-31 T 13-09-2016 IPR008978 HSP20-like chaperone THL1_RS13280 1cc5598d366b99b1d9a81ac98759e5c7 151 Pfam PF00011 Hsp20/alpha crystallin family 53 151 4.3E-19 T 13-09-2016 IPR002068 Alpha crystallin/Hsp20 domain THL1_RS13280 1cc5598d366b99b1d9a81ac98759e5c7 151 PANTHER PTHR11527 11 151 6.2E-26 T 13-09-2016 IPR031107 Small heat shock protein HSP20 THL1_RS13280 1cc5598d366b99b1d9a81ac98759e5c7 151 Gene3D G3DSA:2.60.40.790 10 151 1.5E-31 T 13-09-2016 IPR008978 HSP20-like chaperone THL1_RS22910 4170484625aaa370b8edb8164dbf5845 416 Pfam PF01739 CheR methyltransferase, SAM binding domain 66 240 8.1E-36 T 13-09-2016 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal THL1_RS22910 4170484625aaa370b8edb8164dbf5845 416 PANTHER PTHR24422:SF14 1 414 9.4E-97 T 13-09-2016 THL1_RS22910 4170484625aaa370b8edb8164dbf5845 416 PRINTS PR00996 Glutamate methyltransferase family signature 97 117 6.4E-23 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS22910 4170484625aaa370b8edb8164dbf5845 416 PRINTS PR00996 Glutamate methyltransferase family signature 58 70 6.4E-23 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS22910 4170484625aaa370b8edb8164dbf5845 416 PRINTS PR00996 Glutamate methyltransferase family signature 130 146 6.4E-23 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS22910 4170484625aaa370b8edb8164dbf5845 416 PRINTS PR00996 Glutamate methyltransferase family signature 199 213 6.4E-23 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS22910 4170484625aaa370b8edb8164dbf5845 416 PRINTS PR00996 Glutamate methyltransferase family signature 218 241 6.4E-23 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS22910 4170484625aaa370b8edb8164dbf5845 416 Gene3D G3DSA:3.40.50.150 65 253 5.1E-51 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS22910 4170484625aaa370b8edb8164dbf5845 416 Gene3D G3DSA:1.10.155.10 3 62 8.7E-4 T 13-09-2016 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal THL1_RS22910 4170484625aaa370b8edb8164dbf5845 416 SMART SM00138 3 259 6.9E-30 T 13-09-2016 IPR000780 MCP methyltransferase, CheR-type GO:0008757 THL1_RS22910 4170484625aaa370b8edb8164dbf5845 416 SUPERFAMILY SSF48452 312 409 4.02E-10 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS22910 4170484625aaa370b8edb8164dbf5845 416 Gene3D G3DSA:1.25.40.10 316 407 4.5E-12 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS22910 4170484625aaa370b8edb8164dbf5845 416 SUPERFAMILY SSF53335 65 253 1.44E-42 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS22910 4170484625aaa370b8edb8164dbf5845 416 PANTHER PTHR24422 1 414 9.4E-97 T 13-09-2016 THL1_RS25345 4e5daa4a7cdf0e02ec59eb2a931bdec5 389 Gene3D G3DSA:3.40.50.300 150 370 3.5E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25345 4e5daa4a7cdf0e02ec59eb2a931bdec5 389 Pfam PF16968 Pilus assembly protein TadZ N-terminal 1 126 7.2E-46 T 13-09-2016 IPR031580 Pilus assembly protein TadZ, N-terminal THL1_RS25345 4e5daa4a7cdf0e02ec59eb2a931bdec5 389 SUPERFAMILY SSF52540 150 370 2.05E-19 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS04605 51b3a0da36ee97b5942705b3a7c68efe 128 Pfam PF14248 Domain of unknown function (DUF4345) 4 121 7.7E-25 T 13-09-2016 IPR025597 Protein of unknown function DUF4345 THL1_RS14590 eb01f894f13e591e69a19687a768963f 442 PANTHER PTHR13847 1 423 2.0E-87 T 13-09-2016 THL1_RS14590 eb01f894f13e591e69a19687a768963f 442 Pfam PF01266 FAD dependent oxidoreductase 37 395 2.2E-41 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS14590 eb01f894f13e591e69a19687a768963f 442 PANTHER PTHR13847:SF196 1 423 2.0E-87 T 13-09-2016 THL1_RS14590 eb01f894f13e591e69a19687a768963f 442 SUPERFAMILY SSF51905 36 258 1.68E-32 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS14590 eb01f894f13e591e69a19687a768963f 442 SUPERFAMILY SSF51905 369 409 1.68E-32 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS14590 eb01f894f13e591e69a19687a768963f 442 Gene3D G3DSA:3.50.50.60 359 404 1.4E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS14590 eb01f894f13e591e69a19687a768963f 442 Gene3D G3DSA:3.50.50.60 180 260 1.4E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS14590 eb01f894f13e591e69a19687a768963f 442 Gene3D G3DSA:3.50.50.60 29 127 1.4E-31 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20800 2e34e34d14f99aab9527d08f925a2ef1 572 Pfam PF06980 Protein of unknown function (DUF1302) 32 572 7.0E-113 T 13-09-2016 IPR010727 Protein of unknown function DUF1302 THL1_RS07140 a23b1b936b0980d89bf6d04332b4a5b2 152 Pfam PF13577 SnoaL-like domain 9 132 5.2E-24 T 13-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain THL1_RS07140 a23b1b936b0980d89bf6d04332b4a5b2 152 SUPERFAMILY SSF54427 4 136 2.1E-28 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS07140 a23b1b936b0980d89bf6d04332b4a5b2 152 Gene3D G3DSA:3.10.450.50 9 138 3.4E-22 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS22175 c64ad301f048f1f5a0ab02277c8bdf0a 445 PANTHER PTHR34596 1 445 1.3E-164 T 13-09-2016 THL1_RS22175 c64ad301f048f1f5a0ab02277c8bdf0a 445 Gene3D G3DSA:2.40.160.10 35 445 5.3E-147 T 13-09-2016 IPR023614 Porin domain THL1_RS22175 c64ad301f048f1f5a0ab02277c8bdf0a 445 Pfam PF03573 outer membrane porin, OprD family 30 444 1.0E-151 T 13-09-2016 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 THL1_RS15820 dce868f0fc1d739be8c15d1444471963 283 Pfam PF13557 Putative MetA-pathway of phenol degradation 49 278 1.3E-31 T 13-09-2016 IPR025737 MetA-pathway of phenol degradation, putative THL1_RS00305 2f29fa81a06f85f0c5a2cf2ccc3cef0d 221 SUPERFAMILY SSF161098 11 208 4.84E-41 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00305 2f29fa81a06f85f0c5a2cf2ccc3cef0d 221 PANTHER PTHR30450:SF1 1 221 7.2E-124 T 13-09-2016 THL1_RS00305 2f29fa81a06f85f0c5a2cf2ccc3cef0d 221 Gene3D G3DSA:1.10.3720.10 11 216 5.6E-37 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00305 2f29fa81a06f85f0c5a2cf2ccc3cef0d 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 212 1.0E-18 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00305 2f29fa81a06f85f0c5a2cf2ccc3cef0d 221 PANTHER PTHR30450 1 221 7.2E-124 T 13-09-2016 THL1_RS19460 50d3df45d3ff8ce11966f2a8eceabcbd 131 Pfam PF10975 Protein of unknown function (DUF2802) 58 125 1.6E-24 T 13-09-2016 IPR021244 Protein of unknown function DUF2802 THL1_RS10355 0b87f42e852b0d2f66e429a68161e298 725 Hamap MF_01858 Ribosomal RNA large subunit methyltransferase K/L [rlmL]. 7 725 32.76 T 13-09-2016 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS10355 0b87f42e852b0d2f66e429a68161e298 725 SUPERFAMILY SSF53335 421 720 8.57E-71 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS10355 0b87f42e852b0d2f66e429a68161e298 725 Pfam PF02926 THUMP domain 41 156 1.4E-8 T 13-09-2016 IPR004114 THUMP domain GO:0003723 THL1_RS10355 0b87f42e852b0d2f66e429a68161e298 725 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 486 677 2.1E-20 T 13-09-2016 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 THL1_RS10355 0b87f42e852b0d2f66e429a68161e298 725 SUPERFAMILY SSF53335 265 383 1.07E-35 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS10355 0b87f42e852b0d2f66e429a68161e298 725 SUPERFAMILY SSF53335 143 224 1.07E-35 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS10355 0b87f42e852b0d2f66e429a68161e298 725 PANTHER PTHR18895 427 686 2.2E-113 T 13-09-2016 THL1_RS10355 0b87f42e852b0d2f66e429a68161e298 725 PANTHER PTHR18895:SF62 427 686 2.2E-113 T 13-09-2016 THL1_RS10355 0b87f42e852b0d2f66e429a68161e298 725 Gene3D G3DSA:3.40.50.150 458 723 1.1E-72 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS10355 0b87f42e852b0d2f66e429a68161e298 725 PIRSF PIRSF037618 2 725 0.0 T 13-09-2016 IPR017244 Ribosomal RNA large subunit methyltransferase K/L GO:0005737|GO:0008990|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS10355 0b87f42e852b0d2f66e429a68161e298 725 SMART SM00981 59 157 7.2E-22 T 13-09-2016 IPR004114 THUMP domain GO:0003723 THL1_RS10355 0b87f42e852b0d2f66e429a68161e298 725 Pfam PF01170 Putative RNA methylase family UPF0020 165 380 5.1E-43 T 13-09-2016 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 THL1_RS10355 0b87f42e852b0d2f66e429a68161e298 725 Gene3D G3DSA:3.40.50.150 262 361 9.0E-19 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS10355 0b87f42e852b0d2f66e429a68161e298 725 Gene3D G3DSA:3.40.50.150 150 221 9.0E-19 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS10355 0b87f42e852b0d2f66e429a68161e298 725 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 313 319 - T 13-09-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THL1_RS19175 1aba2a807699bd776c0425c7d74af090 228 Pfam PF02224 Cytidylate kinase 8 221 6.4E-77 T 13-09-2016 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 THL1_RS19175 1aba2a807699bd776c0425c7d74af090 228 Gene3D G3DSA:3.40.50.300 6 221 8.5E-77 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS19175 1aba2a807699bd776c0425c7d74af090 228 TIGRFAM TIGR00017 cmk: cytidylate kinase 6 220 7.5E-82 T 13-09-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 THL1_RS19175 1aba2a807699bd776c0425c7d74af090 228 PANTHER PTHR21299 6 228 1.5E-77 T 13-09-2016 THL1_RS19175 1aba2a807699bd776c0425c7d74af090 228 Hamap MF_00238 Cytidylate kinase [cmk]. 6 225 34.523 T 13-09-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 THL1_RS19175 1aba2a807699bd776c0425c7d74af090 228 SUPERFAMILY SSF52540 6 222 9.94E-47 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS25995 bb0e7e9ab7e2adcdf09eedf919e8e79b 249 Pfam PF11738 Protein of unknown function (DUF3298) 162 233 1.2E-5 T 13-09-2016 IPR021729 Domain of unknown function DUF3298 THL1_RS25995 bb0e7e9ab7e2adcdf09eedf919e8e79b 249 Gene3D G3DSA:3.90.640.20 158 245 4.2E-14 T 13-09-2016 IPR021729 Domain of unknown function DUF3298 THL1_RS25995 bb0e7e9ab7e2adcdf09eedf919e8e79b 249 Gene3D G3DSA:3.30.565.40 43 152 1.8E-13 T 13-09-2016 IPR025303 Domain of unknown function DUF4163 THL1_RS21330 4368d25f4c583394db9ccb2a2829be53 193 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 186 1.1E-29 T 13-09-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS21330 4368d25f4c583394db9ccb2a2829be53 193 SUPERFAMILY SSF88659 123 187 1.87E-17 T 13-09-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS21330 4368d25f4c583394db9ccb2a2829be53 193 Gene3D G3DSA:1.10.10.10 123 188 1.6E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS21330 4368d25f4c583394db9ccb2a2829be53 193 SUPERFAMILY SSF88946 1 108 1.1E-32 T 13-09-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS21330 4368d25f4c583394db9ccb2a2829be53 193 Gene3D G3DSA:1.10.1740.10 2 112 3.8E-38 T 13-09-2016 THL1_RS21330 4368d25f4c583394db9ccb2a2829be53 193 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 47 78 - T 13-09-2016 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS21330 4368d25f4c583394db9ccb2a2829be53 193 PANTHER PTHR30173:SF1 1 187 1.5E-55 T 13-09-2016 THL1_RS21330 4368d25f4c583394db9ccb2a2829be53 193 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 3 190 5.7E-98 T 13-09-2016 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS21330 4368d25f4c583394db9ccb2a2829be53 193 PANTHER PTHR30173 1 187 1.5E-55 T 13-09-2016 THL1_RS21330 4368d25f4c583394db9ccb2a2829be53 193 Pfam PF04542 Sigma-70 region 2 25 92 1.1E-17 T 13-09-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS21330 4368d25f4c583394db9ccb2a2829be53 193 Pfam PF08281 Sigma-70, region 4 132 181 4.6E-18 T 13-09-2016 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THL1_RS28460 0ee1abc527ccc00c7ba7f0df4195a114 290 Pfam PF02195 ParB-like nuclease domain 38 127 1.0E-29 T 13-09-2016 IPR003115 ParB/Sulfiredoxin THL1_RS28460 0ee1abc527ccc00c7ba7f0df4195a114 290 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 35 201 1.3E-61 T 13-09-2016 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 THL1_RS28460 0ee1abc527ccc00c7ba7f0df4195a114 290 PANTHER PTHR33375 1 290 2.3E-105 T 13-09-2016 THL1_RS28460 0ee1abc527ccc00c7ba7f0df4195a114 290 Gene3D G3DSA:3.90.1530.10 29 133 3.6E-43 T 13-09-2016 THL1_RS28460 0ee1abc527ccc00c7ba7f0df4195a114 290 SMART SM00470 37 127 1.2E-39 T 13-09-2016 IPR003115 ParB/Sulfiredoxin THL1_RS28460 0ee1abc527ccc00c7ba7f0df4195a114 290 SUPERFAMILY SSF110849 36 180 9.42E-36 T 13-09-2016 IPR003115 ParB/Sulfiredoxin THL1_RS02480 1d95ab8a5e6d49008c18bb954f715f1b 320 Gene3D G3DSA:1.10.10.10 13 98 3.0E-21 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02480 1d95ab8a5e6d49008c18bb954f715f1b 320 PANTHER PTHR30126 12 275 7.2E-66 T 13-09-2016 THL1_RS02480 1d95ab8a5e6d49008c18bb954f715f1b 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 73 5.0E-16 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS02480 1d95ab8a5e6d49008c18bb954f715f1b 320 Gene3D G3DSA:3.40.190.10 193 277 3.1E-16 T 13-09-2016 THL1_RS02480 1d95ab8a5e6d49008c18bb954f715f1b 320 Pfam PF03466 LysR substrate binding domain 98 310 8.5E-35 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS02480 1d95ab8a5e6d49008c18bb954f715f1b 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 1.5E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS02480 1d95ab8a5e6d49008c18bb954f715f1b 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 1.5E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS02480 1d95ab8a5e6d49008c18bb954f715f1b 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 1.5E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS02480 1d95ab8a5e6d49008c18bb954f715f1b 320 SUPERFAMILY SSF46785 12 121 5.9E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS02480 1d95ab8a5e6d49008c18bb954f715f1b 320 Gene3D G3DSA:3.40.190.10 99 192 6.9E-16 T 13-09-2016 THL1_RS02480 1d95ab8a5e6d49008c18bb954f715f1b 320 PANTHER PTHR30126:SF3 12 275 7.2E-66 T 13-09-2016 THL1_RS02480 1d95ab8a5e6d49008c18bb954f715f1b 320 SUPERFAMILY SSF53850 99 314 2.17E-35 T 13-09-2016 THL1_RS00880 2ad20b04c60cf9e8d8a976c3d6c8710f 98 Pfam PF06155 Protein of unknown function (DUF971) 8 89 2.4E-22 T 13-09-2016 IPR010376 Domain of unknown function DUF971 Reactome: REACT_13|UniPathway: UPA00118 THL1_RS26635 b05b5c0a1a51d65ce9b1763af3c938ed 153 Pfam PF14568 SMI1-KNR4 cell-wall 31 145 3.9E-15 T 13-09-2016 THL1_RS26635 b05b5c0a1a51d65ce9b1763af3c938ed 153 Gene3D G3DSA:3.40.1580.10 1 150 7.4E-37 T 13-09-2016 IPR018958 SMI1/KNR4-like domain THL1_RS26635 b05b5c0a1a51d65ce9b1763af3c938ed 153 SUPERFAMILY SSF160631 1 151 6.54E-36 T 13-09-2016 THL1_RS26635 b05b5c0a1a51d65ce9b1763af3c938ed 153 SMART SM00860 28 147 1.1E-7 T 13-09-2016 IPR018958 SMI1/KNR4-like domain THL1_RS23260 2917b60e6f852f40f6ceec99948ba953 324 PANTHER PTHR33055:SF3 1 318 6.1E-60 T 13-09-2016 THL1_RS23260 2917b60e6f852f40f6ceec99948ba953 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 197 280 1.9E-21 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS23260 2917b60e6f852f40f6ceec99948ba953 324 Pfam PF01548 Transposase 5 153 2.2E-31 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS23260 2917b60e6f852f40f6ceec99948ba953 324 PANTHER PTHR33055 1 318 6.1E-60 T 13-09-2016 THL1_RS12725 9bd08f795ca4ba8f1d3ec2e547fd6066 343 PANTHER PTHR21266:SF23 15 175 6.7E-38 T 13-09-2016 THL1_RS12725 9bd08f795ca4ba8f1d3ec2e547fd6066 343 Pfam PF00355 Rieske [2Fe-2S] domain 18 99 7.6E-18 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS12725 9bd08f795ca4ba8f1d3ec2e547fd6066 343 Gene3D G3DSA:2.102.10.10 17 128 1.7E-31 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS12725 9bd08f795ca4ba8f1d3ec2e547fd6066 343 SUPERFAMILY SSF55961 109 327 9.89E-16 T 13-09-2016 THL1_RS12725 9bd08f795ca4ba8f1d3ec2e547fd6066 343 SUPERFAMILY SSF50022 10 134 3.54E-33 T 13-09-2016 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THL1_RS12725 9bd08f795ca4ba8f1d3ec2e547fd6066 343 PANTHER PTHR21266 15 175 6.7E-38 T 13-09-2016 THL1_RS19540 d3c0d74f32d81a7a4f70fa1f6cd9c717 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 4.4E-16 T 13-09-2016 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 THL1_RS19540 d3c0d74f32d81a7a4f70fa1f6cd9c717 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 4.4E-16 T 13-09-2016 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 THL1_RS19540 d3c0d74f32d81a7a4f70fa1f6cd9c717 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 4.4E-16 T 13-09-2016 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 THL1_RS19540 d3c0d74f32d81a7a4f70fa1f6cd9c717 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 2.2E-28 T 13-09-2016 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 THL1_RS19540 d3c0d74f32d81a7a4f70fa1f6cd9c717 89 PANTHER PTHR34040 1 89 3.9E-38 T 13-09-2016 THL1_RS19540 d3c0d74f32d81a7a4f70fa1f6cd9c717 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 4.9E-29 T 13-09-2016 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 THL1_RS19540 d3c0d74f32d81a7a4f70fa1f6cd9c717 89 PIRSF PIRSF004669 1 89 1.8E-29 T 13-09-2016 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 THL1_RS19540 d3c0d74f32d81a7a4f70fa1f6cd9c717 89 PANTHER PTHR34040:SF2 1 89 3.9E-38 T 13-09-2016 THL1_RS03960 e42903787567ab1fe4c548a145fda6a0 700 Pfam PF06082 Exopolysaccharide biosynthesis protein YbjH 24 684 5.3E-250 T 13-09-2016 IPR010344 Exopolysaccharide biosynthesis protein YbjH THL1_RS01520 e957fe28913e1532d792b4afd072c3a3 135 PANTHER PTHR26402:SF568 8 125 1.4E-93 T 13-09-2016 THL1_RS01520 e957fe28913e1532d792b4afd072c3a3 135 PANTHER PTHR26402 8 125 1.4E-93 T 13-09-2016 THL1_RS01520 e957fe28913e1532d792b4afd072c3a3 135 Pfam PF00072 Response regulator receiver domain 10 121 9.5E-26 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS01520 e957fe28913e1532d792b4afd072c3a3 135 Gene3D G3DSA:3.40.50.2300 5 125 4.3E-36 T 13-09-2016 THL1_RS01520 e957fe28913e1532d792b4afd072c3a3 135 SUPERFAMILY SSF52172 6 126 1.85E-35 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS01520 e957fe28913e1532d792b4afd072c3a3 135 SMART SM00448 8 121 2.7E-36 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS01965 7cc19bfe515bb193295594133f5785cb 470 Pfam PF00324 Amino acid permease 20 427 1.5E-118 T 13-09-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 THL1_RS01965 7cc19bfe515bb193295594133f5785cb 470 PANTHER PTHR11785:SF24 11 462 5.0E-251 T 13-09-2016 THL1_RS01965 7cc19bfe515bb193295594133f5785cb 470 ProSitePatterns PS00218 Amino acid permeases signature. 45 75 - T 13-09-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 THL1_RS01965 7cc19bfe515bb193295594133f5785cb 470 PIRSF PIRSF006060 1 461 2.3E-77 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS01965 7cc19bfe515bb193295594133f5785cb 470 PANTHER PTHR11785 11 462 5.0E-251 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS01965 7cc19bfe515bb193295594133f5785cb 470 TIGRFAM TIGR01773 GABAperm: GABA permease 11 453 4.6E-229 T 13-09-2016 IPR011265 GABA permease GO:0015185|GO:0015812|GO:0016021 THL1_RS21015 0ce769bd5259053e39afe792315ee831 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 13-09-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site THL1_RS21015 0ce769bd5259053e39afe792315ee831 207 SUPERFAMILY SSF46689 6 87 9.98E-20 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21015 0ce769bd5259053e39afe792315ee831 207 PANTHER PTHR30328 5 163 8.3E-27 T 13-09-2016 THL1_RS21015 0ce769bd5259053e39afe792315ee831 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 3.4E-9 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS21015 0ce769bd5259053e39afe792315ee831 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 3.4E-9 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS21015 0ce769bd5259053e39afe792315ee831 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 4.5E-17 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS21015 0ce769bd5259053e39afe792315ee831 207 Gene3D G3DSA:1.10.357.10 5 201 5.6E-37 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS13915 8aa2fec22352154cf48e32f4cfa37527 337 Gene3D G3DSA:1.10.10.10 225 268 3.0E-4 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13915 8aa2fec22352154cf48e32f4cfa37527 337 PANTHER PTHR11019:SF46 218 336 1.4E-22 T 13-09-2016 THL1_RS13915 8aa2fec22352154cf48e32f4cfa37527 337 PANTHER PTHR11019 218 336 1.4E-22 T 13-09-2016 THL1_RS13915 8aa2fec22352154cf48e32f4cfa37527 337 SUPERFAMILY SSF46689 282 332 5.38E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13915 8aa2fec22352154cf48e32f4cfa37527 337 SMART SM00342 246 328 3.8E-20 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS13915 8aa2fec22352154cf48e32f4cfa37527 337 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 21 202 6.5E-52 T 13-09-2016 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal THL1_RS13915 8aa2fec22352154cf48e32f4cfa37527 337 Gene3D G3DSA:1.10.10.60 282 332 1.2E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13915 8aa2fec22352154cf48e32f4cfa37527 337 Pfam PF12833 Helix-turn-helix domain 252 329 4.3E-15 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS23730 ee92a2337dac4af84884661bc8eb5fbd 455 Pfam PF07044 Protein of unknown function (DUF1329) 85 450 6.6E-160 T 13-09-2016 IPR010752 Protein of unknown function DUF1329 THL1_RS23730 ee92a2337dac4af84884661bc8eb5fbd 455 Gene3D G3DSA:2.50.20.10 161 309 2.0E-36 T 13-09-2016 THL1_RS23730 ee92a2337dac4af84884661bc8eb5fbd 455 Gene3D G3DSA:2.50.20.10 342 450 2.0E-36 T 13-09-2016 THL1_RS09535 060acfbb186f048b5c7d19bca70726a8 1162 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1146 1.2E-67 T 13-09-2016 IPR003395 RecF/RecN/SMC, N-terminal THL1_RS09535 060acfbb186f048b5c7d19bca70726a8 1162 SMART SM00968 520 615 2.2E-8 T 13-09-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 THL1_RS09535 060acfbb186f048b5c7d19bca70726a8 1162 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1155 22.993 T 13-09-2016 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 THL1_RS09535 060acfbb186f048b5c7d19bca70726a8 1162 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1153 0.0 T 13-09-2016 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 THL1_RS09535 060acfbb186f048b5c7d19bca70726a8 1162 SUPERFAMILY SSF75553 485 662 6.8E-6 T 13-09-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 THL1_RS09535 060acfbb186f048b5c7d19bca70726a8 1162 PANTHER PTHR18937:SF261 1 1161 0.0 T 13-09-2016 THL1_RS09535 060acfbb186f048b5c7d19bca70726a8 1162 SUPERFAMILY SSF57997 222 487 2.75E-5 T 13-09-2016 THL1_RS09535 060acfbb186f048b5c7d19bca70726a8 1162 SUPERFAMILY SSF52540 772 787 1.57E-34 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09535 060acfbb186f048b5c7d19bca70726a8 1162 SUPERFAMILY SSF52540 955 1156 1.57E-34 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09535 060acfbb186f048b5c7d19bca70726a8 1162 SUPERFAMILY SSF52540 817 857 1.57E-34 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09535 060acfbb186f048b5c7d19bca70726a8 1162 SUPERFAMILY SSF52540 1052 1138 5.77E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09535 060acfbb186f048b5c7d19bca70726a8 1162 SUPERFAMILY SSF52540 1 212 5.77E-51 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09535 060acfbb186f048b5c7d19bca70726a8 1162 PANTHER PTHR18937 1 1161 0.0 T 13-09-2016 THL1_RS09535 060acfbb186f048b5c7d19bca70726a8 1162 Gene3D G3DSA:3.40.50.300 1046 1159 3.5E-76 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09535 060acfbb186f048b5c7d19bca70726a8 1162 Gene3D G3DSA:3.40.50.300 656 679 3.5E-76 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09535 060acfbb186f048b5c7d19bca70726a8 1162 Gene3D G3DSA:3.40.50.300 1 187 3.5E-76 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07980 c3a37653d1e6fae8b592095b386fd966 499 PANTHER PTHR31806 17 480 8.1E-90 T 13-09-2016 THL1_RS07980 c3a37653d1e6fae8b592095b386fd966 499 PIRSF PIRSF002744 1 478 4.3E-102 T 13-09-2016 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 THL1_RS07980 c3a37653d1e6fae8b592095b386fd966 499 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 26 455 4.0E-40 T 13-09-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 THL1_RS13535 c68d5bebc4d788844d55e9d9495a1c36 173 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 8 168 3.1E-59 T 13-09-2016 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530|UniPathway: UPA00792 THL1_RS13535 c68d5bebc4d788844d55e9d9495a1c36 173 Pfam PF13671 AAA domain 8 137 1.5E-8 T 13-09-2016 THL1_RS13535 c68d5bebc4d788844d55e9d9495a1c36 173 Gene3D G3DSA:3.40.50.300 6 168 1.2E-58 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS13535 c68d5bebc4d788844d55e9d9495a1c36 173 SUPERFAMILY SSF52540 7 168 3.09E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS13535 c68d5bebc4d788844d55e9d9495a1c36 173 PANTHER PTHR11603 1 168 2.1E-65 T 13-09-2016 THL1_RS05680 6a8bafb2a5a244fcdc54fb2d8eb49984 151 Pfam PF05258 Protein of unknown function (DUF721) 15 98 5.5E-12 T 13-09-2016 IPR007922 Protein of unknown function DUF721/UPF0232 THL1_RS13950 b51072987796987539f7cd5c24404ed9 117 Pfam PF11742 Protein of unknown function (DUF3302) 2 77 1.0E-40 T 13-09-2016 IPR011223 Uncharacterised conserved protein UCP028770 THL1_RS13950 b51072987796987539f7cd5c24404ed9 117 PIRSF PIRSF028770 1 114 2.1E-51 T 13-09-2016 IPR011223 Uncharacterised conserved protein UCP028770 THL1_RS22405 94a36a2d9fd963499a10f6aafcbbc031 104 SUPERFAMILY SSF54909 4 85 5.03E-23 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS22405 94a36a2d9fd963499a10f6aafcbbc031 104 PANTHER PTHR33336 2 104 2.9E-21 T 13-09-2016 THL1_RS22405 94a36a2d9fd963499a10f6aafcbbc031 104 Gene3D G3DSA:3.30.70.900 4 89 8.4E-22 T 13-09-2016 THL1_RS22405 94a36a2d9fd963499a10f6aafcbbc031 104 Pfam PF03992 Antibiotic biosynthesis monooxygenase 7 74 2.8E-18 T 13-09-2016 IPR007138 Antibiotic biosynthesis monooxygenase domain THL1_RS04775 b83931f44814e8154ebc23e47354cff2 406 PANTHER PTHR11118:SF3 9 406 9.5E-205 T 13-09-2016 THL1_RS04775 b83931f44814e8154ebc23e47354cff2 406 Pfam PF01139 tRNA-splicing ligase RtcB 33 406 2.0E-131 T 13-09-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 THL1_RS04775 b83931f44814e8154ebc23e47354cff2 406 SUPERFAMILY SSF103365 9 406 4.05E-141 T 13-09-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 THL1_RS04775 b83931f44814e8154ebc23e47354cff2 406 ProSitePatterns PS01288 Uncharacterized protein family UPF0027 signature. 33 62 - T 13-09-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 THL1_RS04775 b83931f44814e8154ebc23e47354cff2 406 PANTHER PTHR11118 9 406 9.5E-205 T 13-09-2016 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 THL1_RS23125 da37f5cb90f55049f93ca858bf7ed3cc 200 Gene3D G3DSA:3.90.79.10 21 183 1.7E-37 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS23125 da37f5cb90f55049f93ca858bf7ed3cc 200 Pfam PF00293 NUDIX domain 26 107 1.6E-11 T 13-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 THL1_RS23125 da37f5cb90f55049f93ca858bf7ed3cc 200 SUPERFAMILY SSF55811 4 175 1.02E-33 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS23125 da37f5cb90f55049f93ca858bf7ed3cc 200 PANTHER PTHR12992 1 183 1.7E-52 T 13-09-2016 THL1_RS27730 8d15c6dee9e9a11b54986bb15af912c7 77 Pfam PF13711 Domain of unknown function (DUF4160) 10 70 1.4E-10 T 13-09-2016 IPR025427 Protein of unknown function DUF4160 THL1_RS16880 7ccd2420fba8e0187471a5fd048ba1e4 550 PANTHER PTHR11814:SF112 15 541 5.3E-247 T 13-09-2016 THL1_RS16880 7ccd2420fba8e0187471a5fd048ba1e4 550 SUPERFAMILY SSF52091 436 535 9.03E-20 T 13-09-2016 IPR002645 STAS domain THL1_RS16880 7ccd2420fba8e0187471a5fd048ba1e4 550 Pfam PF01740 STAS domain 437 528 1.4E-16 T 13-09-2016 IPR002645 STAS domain THL1_RS16880 7ccd2420fba8e0187471a5fd048ba1e4 550 Gene3D G3DSA:3.30.750.24 436 539 2.0E-19 T 13-09-2016 IPR002645 STAS domain THL1_RS16880 7ccd2420fba8e0187471a5fd048ba1e4 550 PANTHER PTHR11814 15 541 5.3E-247 T 13-09-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 THL1_RS16880 7ccd2420fba8e0187471a5fd048ba1e4 550 Pfam PF00916 Sulfate permease family 21 384 2.2E-84 T 13-09-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 THL1_RS00190 b4066fa47d346445f4bf186e166cbc47 332 Pfam PF00296 Luciferase-like monooxygenase 14 298 2.4E-38 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS00190 b4066fa47d346445f4bf186e166cbc47 332 SUPERFAMILY SSF51679 7 329 2.88E-84 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS00190 b4066fa47d346445f4bf186e166cbc47 332 Gene3D G3DSA:3.20.20.30 8 329 3.9E-87 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS00190 b4066fa47d346445f4bf186e166cbc47 332 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 9 329 1.6E-127 T 13-09-2016 IPR019949 Luciferase family oxidoreductase, group 1 THL1_RS00190 b4066fa47d346445f4bf186e166cbc47 332 PANTHER PTHR30137:SF2 1 330 8.1E-137 T 13-09-2016 THL1_RS00190 b4066fa47d346445f4bf186e166cbc47 332 PANTHER PTHR30137 1 330 8.1E-137 T 13-09-2016 THL1_RS07560 e7a80614ea52212758c2e1bc223be8a3 105 PANTHER PTHR34068 1 105 8.0E-45 T 13-09-2016 THL1_RS07560 e7a80614ea52212758c2e1bc223be8a3 105 Pfam PF01906 Putative heavy-metal-binding 1 105 4.5E-41 T 13-09-2016 IPR002765 Uncharacterised protein family UPF0145 THL1_RS07560 e7a80614ea52212758c2e1bc223be8a3 105 Gene3D G3DSA:3.30.110.70 1 105 6.3E-39 T 13-09-2016 IPR002765 Uncharacterised protein family UPF0145 THL1_RS07560 e7a80614ea52212758c2e1bc223be8a3 105 PANTHER PTHR34068:SF1 1 105 8.0E-45 T 13-09-2016 THL1_RS07560 e7a80614ea52212758c2e1bc223be8a3 105 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 105 25.426 T 13-09-2016 IPR002765 Uncharacterised protein family UPF0145 THL1_RS07560 e7a80614ea52212758c2e1bc223be8a3 105 SUPERFAMILY SSF117782 1 105 3.79E-39 T 13-09-2016 IPR002765 Uncharacterised protein family UPF0145 THL1_RS05505 6f9c53bf0d26e78c5304c4def040c8bf 321 Gene3D G3DSA:1.25.40.10 148 182 1.1E-4 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS05505 6f9c53bf0d26e78c5304c4def040c8bf 321 Gene3D G3DSA:1.25.40.10 243 311 1.1E-4 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS20825 9bfb408b46f2a100b2ad3eaeaf49a135 452 Gene3D G3DSA:2.50.20.10 338 420 1.1E-23 T 13-09-2016 THL1_RS20825 9bfb408b46f2a100b2ad3eaeaf49a135 452 Gene3D G3DSA:2.50.20.10 158 304 1.1E-23 T 13-09-2016 THL1_RS20825 9bfb408b46f2a100b2ad3eaeaf49a135 452 Pfam PF07044 Protein of unknown function (DUF1329) 83 446 9.4E-110 T 13-09-2016 IPR010752 Protein of unknown function DUF1329 THL1_RS15225 f9d4767ba0e2d2a89f62c73dff4f93da 113 Pfam PF10734 Protein of unknown function (DUF2523) 34 104 2.5E-10 T 13-09-2016 IPR019670 Protein of unkown function DUF2523 THL1_RS14050 e01fb9a5d04c700c8da7fa62da95b139 527 SUPERFAMILY SSF53187 324 353 3.25E-35 T 13-09-2016 THL1_RS14050 e01fb9a5d04c700c8da7fa62da95b139 527 SUPERFAMILY SSF53187 398 468 3.25E-35 T 13-09-2016 THL1_RS14050 e01fb9a5d04c700c8da7fa62da95b139 527 SUPERFAMILY SSF53187 6 193 3.25E-35 T 13-09-2016 THL1_RS14050 e01fb9a5d04c700c8da7fa62da95b139 527 PANTHER PTHR30575 392 487 4.7E-30 T 13-09-2016 THL1_RS14050 e01fb9a5d04c700c8da7fa62da95b139 527 PANTHER PTHR30575 1 89 4.7E-30 T 13-09-2016 THL1_RS14050 e01fb9a5d04c700c8da7fa62da95b139 527 PANTHER PTHR30575 219 355 4.7E-30 T 13-09-2016 THL1_RS14050 e01fb9a5d04c700c8da7fa62da95b139 527 PANTHER PTHR30575 109 200 4.7E-30 T 13-09-2016 THL1_RS14050 e01fb9a5d04c700c8da7fa62da95b139 527 Gene3D G3DSA:3.40.630.10 337 359 4.3E-33 T 13-09-2016 THL1_RS14050 e01fb9a5d04c700c8da7fa62da95b139 527 Gene3D G3DSA:3.40.630.10 5 190 4.3E-33 T 13-09-2016 THL1_RS14050 e01fb9a5d04c700c8da7fa62da95b139 527 Gene3D G3DSA:3.40.630.10 398 478 4.3E-33 T 13-09-2016 THL1_RS08370 41c1fd569c567b54e66397e0b2a7b44d 293 Gene3D G3DSA:3.40.190.10 93 178 3.4E-24 T 13-09-2016 THL1_RS08370 41c1fd569c567b54e66397e0b2a7b44d 293 Gene3D G3DSA:3.40.190.10 198 255 3.1E-9 T 13-09-2016 THL1_RS08370 41c1fd569c567b54e66397e0b2a7b44d 293 SUPERFAMILY SSF46785 2 86 2.27E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08370 41c1fd569c567b54e66397e0b2a7b44d 293 SUPERFAMILY SSF53850 82 292 1.99E-33 T 13-09-2016 THL1_RS08370 41c1fd569c567b54e66397e0b2a7b44d 293 Gene3D G3DSA:1.10.10.10 2 86 1.5E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS08370 41c1fd569c567b54e66397e0b2a7b44d 293 Pfam PF03466 LysR substrate binding domain 89 291 1.4E-27 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS08370 41c1fd569c567b54e66397e0b2a7b44d 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 5.6E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08370 41c1fd569c567b54e66397e0b2a7b44d 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 5.6E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08370 41c1fd569c567b54e66397e0b2a7b44d 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 5.6E-6 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08370 41c1fd569c567b54e66397e0b2a7b44d 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 1.6E-18 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS08370 41c1fd569c567b54e66397e0b2a7b44d 293 PANTHER PTHR30537 1 292 1.7E-101 T 13-09-2016 THL1_RS08370 41c1fd569c567b54e66397e0b2a7b44d 293 PANTHER PTHR30537:SF26 1 292 1.7E-101 T 13-09-2016 THL1_RS23500 27d1aa4f736340aed2bb0cc48c2d83a8 84 Gene3D G3DSA:1.10.10.710 18 80 1.8E-26 T 13-09-2016 IPR009813 Uncharacterised protein family YebG THL1_RS23500 27d1aa4f736340aed2bb0cc48c2d83a8 84 Pfam PF07130 YebG protein 1 72 5.5E-27 T 13-09-2016 IPR009813 Uncharacterised protein family YebG THL1_RS18765 84bd95140e20771b68e683643606a6ea 461 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 54 308 1.2E-61 T 13-09-2016 IPR031811 AlgX, SGNH hydrolase-like domain KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.-|UniPathway: UPA00286 THL1_RS18765 84bd95140e20771b68e683643606a6ea 461 Pfam PF16824 C-terminal carbohydrate-binding module 329 444 7.9E-28 T 13-09-2016 IPR031798 Alginate biosynthesis protein AlgX, C-terminal carbohydrate-binding module KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.-|UniPathway: UPA00286 THL1_RS20390 b6663b8809f9f6ac0ecee73685c01374 64 Pfam PF14549 DNA-binding transcriptional regulator Cro 3 55 3.4E-22 T 13-09-2016 THL1_RS20390 b6663b8809f9f6ac0ecee73685c01374 64 SUPERFAMILY SSF47413 1 54 4.5E-15 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS20390 b6663b8809f9f6ac0ecee73685c01374 64 Gene3D G3DSA:1.10.260.40 1 53 3.1E-21 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS24340 38ebef0295469eb9eb18527cd04221e9 971 PANTHER PTHR30441 804 876 3.0E-118 T 13-09-2016 THL1_RS24340 38ebef0295469eb9eb18527cd04221e9 971 Gene3D G3DSA:3.30.1330.60 786 830 6.0E-10 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS24340 38ebef0295469eb9eb18527cd04221e9 971 Gene3D G3DSA:3.30.1330.60 916 946 6.0E-10 T 13-09-2016 IPR006665 OmpA-like domain THL1_RS24340 38ebef0295469eb9eb18527cd04221e9 971 Pfam PF05359 Domain of Unknown Function (DUF748) 140 290 6.9E-28 T 13-09-2016 IPR008023 Protein of unknown function DUF748 THL1_RS24340 38ebef0295469eb9eb18527cd04221e9 971 Pfam PF05359 Domain of Unknown Function (DUF748) 360 509 5.7E-33 T 13-09-2016 IPR008023 Protein of unknown function DUF748 THL1_RS24340 38ebef0295469eb9eb18527cd04221e9 971 Pfam PF05359 Domain of Unknown Function (DUF748) 575 720 5.0E-42 T 13-09-2016 IPR008023 Protein of unknown function DUF748 THL1_RS24340 38ebef0295469eb9eb18527cd04221e9 971 PANTHER PTHR30441:SF2 1 751 3.0E-118 T 13-09-2016 THL1_RS24340 38ebef0295469eb9eb18527cd04221e9 971 PANTHER PTHR30441:SF2 804 876 3.0E-118 T 13-09-2016 THL1_RS24340 38ebef0295469eb9eb18527cd04221e9 971 PANTHER PTHR30441 1 751 3.0E-118 T 13-09-2016 THL1_RS18200 17df9467f0c6d0f75b305761caa9b96f 508 Pfam PF14402 7 transmembrane helices usually fused to an inactive transglutaminase 196 505 4.4E-117 T 13-09-2016 IPR025840 7 transmembrane helices usually fused to an inactive transglutaminase THL1_RS18200 17df9467f0c6d0f75b305761caa9b96f 508 Pfam PF14400 Inactive transglutaminase fused to 7 transmembrane helices 25 184 5.9E-47 T 13-09-2016 IPR025838 Inactive transglutaminase fused to 7 transmembrane helices THL1_RS15010 bdd009c30b22a37e53bd67bc9d218d64 393 Pfam PF05707 Zonular occludens toxin (Zot) 1 180 9.0E-17 T 13-09-2016 IPR008900 Zona occludens toxin THL1_RS15010 bdd009c30b22a37e53bd67bc9d218d64 393 Gene3D G3DSA:3.40.50.300 1 179 4.3E-39 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14950 bdd009c30b22a37e53bd67bc9d218d64 393 Pfam PF05707 Zonular occludens toxin (Zot) 1 180 9.0E-17 T 13-09-2016 IPR008900 Zona occludens toxin THL1_RS14950 bdd009c30b22a37e53bd67bc9d218d64 393 Gene3D G3DSA:3.40.50.300 1 179 4.3E-39 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS08145 0c0aacd56d1b2539ad9b206193c2197b 156 PANTHER PTHR33747 1 154 2.0E-25 T 13-09-2016 THL1_RS08145 0c0aacd56d1b2539ad9b206193c2197b 156 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 2 129 26.661 T 13-09-2016 IPR023006 Uncharacterised protein family UPF0225 THL1_RS08145 0c0aacd56d1b2539ad9b206193c2197b 156 Pfam PF02810 SEC-C motif 136 152 1.3E-9 T 13-09-2016 IPR004027 SEC-C motif THL1_RS08145 0c0aacd56d1b2539ad9b206193c2197b 156 Gene3D G3DSA:3.10.450.50 3 153 4.0E-52 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS08145 0c0aacd56d1b2539ad9b206193c2197b 156 SUPERFAMILY SSF54427 25 130 4.47E-31 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS08145 0c0aacd56d1b2539ad9b206193c2197b 156 SUPERFAMILY SSF103642 133 154 7.19E-8 T 13-09-2016 THL1_RS12775 58163095cb37c6173dc9a0e6a55d3ab7 152 SUPERFAMILY SSF52833 27 101 8.2E-5 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS12775 58163095cb37c6173dc9a0e6a55d3ab7 152 Pfam PF04214 Protein of unknown function, DUF 58 123 2.6E-28 T 13-09-2016 IPR007332 Protein of unknown function DUF411 THL1_RS06455 c2c4aa8efff9a560ee39073966929e42 490 Pfam PF01384 Phosphate transporter family 30 180 2.4E-36 T 13-09-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 THL1_RS06455 c2c4aa8efff9a560ee39073966929e42 490 Pfam PF01384 Phosphate transporter family 201 478 3.3E-44 T 13-09-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 THL1_RS06455 c2c4aa8efff9a560ee39073966929e42 490 PANTHER PTHR11101 2 490 1.1E-197 T 13-09-2016 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: REACT_15518 THL1_RS06455 c2c4aa8efff9a560ee39073966929e42 490 Gene3D G3DSA:1.20.1250.20 52 200 2.2E-4 T 13-09-2016 THL1_RS06455 c2c4aa8efff9a560ee39073966929e42 490 PANTHER PTHR11101:SF59 2 490 1.1E-197 T 13-09-2016 THL1_RS15755 102dfbceaba39c35d1871ad3594e4cf3 177 SUPERFAMILY SSF117916 23 114 5.89E-22 T 13-09-2016 THL1_RS15755 102dfbceaba39c35d1871ad3594e4cf3 177 Pfam PF01883 Domain of unknown function DUF59 24 83 9.6E-14 T 13-09-2016 IPR002744 Domain of unknown function DUF59 THL1_RS15755 102dfbceaba39c35d1871ad3594e4cf3 177 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 31 177 9.3E-60 T 13-09-2016 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit UniPathway: UPA00930 THL1_RS08255 bfee470850a80576ae5f62d39ea443c2 131 Pfam PF04343 Protein of unknown function, DUF488 4 111 1.9E-28 T 13-09-2016 IPR007438 Protein of unknown function DUF488 THL1_RS08255 bfee470850a80576ae5f62d39ea443c2 131 PANTHER PTHR36849:SF1 1 117 2.2E-50 T 13-09-2016 THL1_RS08255 bfee470850a80576ae5f62d39ea443c2 131 PANTHER PTHR36849 1 117 2.2E-50 T 13-09-2016 THL1_RS06375 19e7b780e81cdd7cb7f2b8ec70657f6b 219 Pfam PF02230 Phospholipase/Carboxylesterase 5 213 1.9E-39 T 13-09-2016 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 THL1_RS06375 19e7b780e81cdd7cb7f2b8ec70657f6b 219 PANTHER PTHR10655:SF17 1 213 7.4E-57 T 13-09-2016 THL1_RS06375 19e7b780e81cdd7cb7f2b8ec70657f6b 219 Gene3D G3DSA:3.40.50.1820 5 216 5.0E-63 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS06375 19e7b780e81cdd7cb7f2b8ec70657f6b 219 SUPERFAMILY SSF53474 10 217 6.68E-47 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS06375 19e7b780e81cdd7cb7f2b8ec70657f6b 219 PANTHER PTHR10655 1 213 7.4E-57 T 13-09-2016 THL1_RS17710 81aff8ee057afeb78e9dde789325b3e1 427 SUPERFAMILY SSF51905 345 413 4.01E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS17710 81aff8ee057afeb78e9dde789325b3e1 427 SUPERFAMILY SSF51905 30 253 4.01E-44 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS17710 81aff8ee057afeb78e9dde789325b3e1 427 Pfam PF01266 FAD dependent oxidoreductase 31 381 4.3E-53 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS17710 81aff8ee057afeb78e9dde789325b3e1 427 PANTHER PTHR13847 1 424 1.8E-246 T 13-09-2016 THL1_RS17710 81aff8ee057afeb78e9dde789325b3e1 427 PANTHER PTHR13847:SF210 1 424 1.8E-246 T 13-09-2016 THL1_RS17710 81aff8ee057afeb78e9dde789325b3e1 427 Gene3D G3DSA:3.50.50.60 345 398 2.6E-49 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS17710 81aff8ee057afeb78e9dde789325b3e1 427 Gene3D G3DSA:3.50.50.60 173 252 2.6E-49 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS17710 81aff8ee057afeb78e9dde789325b3e1 427 Gene3D G3DSA:3.50.50.60 18 120 2.6E-49 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS18645 c172c4f5b5270dedf703c95c1bc6f6e9 78 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.776 T 13-09-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 THL1_RS18645 c172c4f5b5270dedf703c95c1bc6f6e9 78 SUPERFAMILY SSF47336 2 76 1.44E-24 T 13-09-2016 IPR009081 Phosphopantetheine binding ACP domain THL1_RS18645 c172c4f5b5270dedf703c95c1bc6f6e9 78 Pfam PF00550 Phosphopantetheine attachment site 6 73 1.3E-17 T 13-09-2016 IPR009081 Phosphopantetheine binding ACP domain THL1_RS18645 c172c4f5b5270dedf703c95c1bc6f6e9 78 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 13-09-2016 IPR006162 Phosphopantetheine attachment site THL1_RS18645 c172c4f5b5270dedf703c95c1bc6f6e9 78 PANTHER PTHR20863 4 78 3.5E-33 T 13-09-2016 THL1_RS18645 c172c4f5b5270dedf703c95c1bc6f6e9 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 76 2.2E-37 T 13-09-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 THL1_RS18645 c172c4f5b5270dedf703c95c1bc6f6e9 78 Gene3D G3DSA:1.10.1200.10 3 77 2.2E-36 T 13-09-2016 IPR009081 Phosphopantetheine binding ACP domain THL1_RS18645 c172c4f5b5270dedf703c95c1bc6f6e9 78 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 76 3.0E-13 T 13-09-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 THL1_RS14580 c27049c6d6fc238c77645871b077a70f 374 SUPERFAMILY SSF55909 37 372 3.93E-108 T 13-09-2016 THL1_RS14580 c27049c6d6fc238c77645871b077a70f 374 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 42 372 6.9E-99 T 13-09-2016 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 THL1_RS14580 c27049c6d6fc238c77645871b077a70f 374 PANTHER PTHR31377 39 372 3.5E-102 T 13-09-2016 THL1_RS14580 c27049c6d6fc238c77645871b077a70f 374 PANTHER PTHR31377:SF0 39 372 3.5E-102 T 13-09-2016 THL1_RS14580 c27049c6d6fc238c77645871b077a70f 374 Gene3D G3DSA:3.75.10.10 37 372 1.8E-111 T 13-09-2016 THL1_RS21415 0f88c043f502712a0f5b6fc6ace35dfc 293 SUPERFAMILY SSF46689 242 289 2.51E-12 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21415 0f88c043f502712a0f5b6fc6ace35dfc 293 Gene3D G3DSA:1.10.10.60 242 289 2.4E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21415 0f88c043f502712a0f5b6fc6ace35dfc 293 Gene3D G3DSA:2.60.120.280 29 174 1.5E-28 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS21415 0f88c043f502712a0f5b6fc6ace35dfc 293 Pfam PF12833 Helix-turn-helix domain 211 289 2.1E-16 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS21415 0f88c043f502712a0f5b6fc6ace35dfc 293 Pfam PF02311 AraC-like ligand binding domain 48 147 1.6E-21 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS21415 0f88c043f502712a0f5b6fc6ace35dfc 293 Gene3D G3DSA:1.10.10.60 191 241 2.6E-9 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21415 0f88c043f502712a0f5b6fc6ace35dfc 293 PANTHER PTHR11019 51 292 1.6E-31 T 13-09-2016 THL1_RS21415 0f88c043f502712a0f5b6fc6ace35dfc 293 SUPERFAMILY SSF51215 29 174 9.81E-28 T 13-09-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 THL1_RS21415 0f88c043f502712a0f5b6fc6ace35dfc 293 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 257 272 1.4E-6 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS21415 0f88c043f502712a0f5b6fc6ace35dfc 293 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 272 288 1.4E-6 T 13-09-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THL1_RS21415 0f88c043f502712a0f5b6fc6ace35dfc 293 SMART SM00342 205 288 8.7E-23 T 13-09-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THL1_RS21415 0f88c043f502712a0f5b6fc6ace35dfc 293 SUPERFAMILY SSF46689 192 236 5.64E-6 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS21415 0f88c043f502712a0f5b6fc6ace35dfc 293 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 242 284 - T 13-09-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THL1_RS20550 8c78c5b583139f84f61c15e8d0b5a41e 170 PANTHER PTHR30466:SF1 13 164 3.1E-39 T 13-09-2016 THL1_RS20550 8c78c5b583139f84f61c15e8d0b5a41e 170 Pfam PF01613 Flavin reductase like domain 23 166 8.6E-37 T 13-09-2016 IPR002563 Flavin reductase like domain GO:0010181 THL1_RS20550 8c78c5b583139f84f61c15e8d0b5a41e 170 SUPERFAMILY SSF50475 13 166 2.36E-48 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS20550 8c78c5b583139f84f61c15e8d0b5a41e 170 Gene3D G3DSA:2.30.110.10 12 164 1.2E-54 T 13-09-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 THL1_RS20550 8c78c5b583139f84f61c15e8d0b5a41e 170 PANTHER PTHR30466 13 164 3.1E-39 T 13-09-2016 THL1_RS20550 8c78c5b583139f84f61c15e8d0b5a41e 170 SMART SM00903 22 166 3.5E-57 T 13-09-2016 IPR002563 Flavin reductase like domain GO:0010181 THL1_RS02965 691bf62b4d9a10f3ec5116aa36b111c8 543 SMART SM00283 274 542 3.4E-51 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS02965 691bf62b4d9a10f3ec5116aa36b111c8 543 Gene3D G3DSA:1.10.287.950 298 513 1.6E-46 T 13-09-2016 THL1_RS02965 691bf62b4d9a10f3ec5116aa36b111c8 543 PANTHER PTHR32089 83 543 5.1E-86 T 13-09-2016 THL1_RS02965 691bf62b4d9a10f3ec5116aa36b111c8 543 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 336 541 1.2E-40 T 13-09-2016 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 THL1_RS02965 691bf62b4d9a10f3ec5116aa36b111c8 543 SMART SM00304 213 266 2.9E-8 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS02965 691bf62b4d9a10f3ec5116aa36b111c8 543 SUPERFAMILY SSF58104 240 543 7.59E-61 T 13-09-2016 THL1_RS02965 691bf62b4d9a10f3ec5116aa36b111c8 543 Pfam PF12729 Four helix bundle sensory module for signal transduction 7 172 3.8E-11 T 13-09-2016 IPR024478 4HB MCP domain THL1_RS02965 691bf62b4d9a10f3ec5116aa36b111c8 543 Pfam PF00672 HAMP domain 195 262 4.3E-15 T 13-09-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 THL1_RS21720 50694ff2f28123d6dadcd73c29aed0cd 762 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 7 759 0.0 T 13-09-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 THL1_RS21720 50694ff2f28123d6dadcd73c29aed0cd 762 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 433 755 8.0E-152 T 13-09-2016 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 THL1_RS21720 50694ff2f28123d6dadcd73c29aed0cd 762 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 4 315 3.5E-119 T 13-09-2016 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 THL1_RS21720 50694ff2f28123d6dadcd73c29aed0cd 762 SUPERFAMILY SSF51726 4 395 1.7E-116 T 13-09-2016 THL1_RS21720 50694ff2f28123d6dadcd73c29aed0cd 762 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 2 760 37.371 T 13-09-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 THL1_RS21720 50694ff2f28123d6dadcd73c29aed0cd 762 PANTHER PTHR30519 1 762 0.0 T 13-09-2016 THL1_RS21720 50694ff2f28123d6dadcd73c29aed0cd 762 PIRSF PIRSF000382 1 762 0.0 T 13-09-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 THL1_RS21720 50694ff2f28123d6dadcd73c29aed0cd 762 Gene3D G3DSA:3.20.20.210 4 391 8.3E-152 T 13-09-2016 THL1_RS21720 50694ff2f28123d6dadcd73c29aed0cd 762 Gene3D G3DSA:3.20.20.210 394 760 6.9E-132 T 13-09-2016 THL1_RS21720 50694ff2f28123d6dadcd73c29aed0cd 762 PANTHER PTHR30519:SF0 1 762 0.0 T 13-09-2016 THL1_RS21720 50694ff2f28123d6dadcd73c29aed0cd 762 SUPERFAMILY SSF51726 398 759 7.19E-119 T 13-09-2016 THL1_RS19940 8b2a14f6720aad5b6bc5cb62e50ba249 310 SUPERFAMILY SSF46785 4 87 3.25E-20 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19940 8b2a14f6720aad5b6bc5cb62e50ba249 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.5E-19 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19940 8b2a14f6720aad5b6bc5cb62e50ba249 310 Gene3D G3DSA:3.40.190.10 175 263 1.4E-14 T 13-09-2016 THL1_RS19940 8b2a14f6720aad5b6bc5cb62e50ba249 310 PANTHER PTHR30537:SF5 1 306 7.1E-96 T 13-09-2016 THL1_RS19940 8b2a14f6720aad5b6bc5cb62e50ba249 310 Gene3D G3DSA:3.40.190.10 92 174 2.2E-21 T 13-09-2016 THL1_RS19940 8b2a14f6720aad5b6bc5cb62e50ba249 310 PANTHER PTHR30537 1 306 7.1E-96 T 13-09-2016 THL1_RS19940 8b2a14f6720aad5b6bc5cb62e50ba249 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.4E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19940 8b2a14f6720aad5b6bc5cb62e50ba249 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.4E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19940 8b2a14f6720aad5b6bc5cb62e50ba249 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.4E-5 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19940 8b2a14f6720aad5b6bc5cb62e50ba249 310 Pfam PF03466 LysR substrate binding domain 88 295 1.5E-41 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS19940 8b2a14f6720aad5b6bc5cb62e50ba249 310 Gene3D G3DSA:1.10.10.10 3 85 2.0E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS19940 8b2a14f6720aad5b6bc5cb62e50ba249 310 SUPERFAMILY SSF53850 89 300 3.88E-42 T 13-09-2016 THL1_RS01140 7f45198b009ee28a637ee16554e4436b 569 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 245 261 1.8E-61 T 13-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 THL1_RS01140 7f45198b009ee28a637ee16554e4436b 569 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 437 452 1.8E-61 T 13-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 THL1_RS01140 7f45198b009ee28a637ee16554e4436b 569 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 460 477 1.8E-61 T 13-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 THL1_RS01140 7f45198b009ee28a637ee16554e4436b 569 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 128 146 1.8E-61 T 13-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 THL1_RS01140 7f45198b009ee28a637ee16554e4436b 569 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 276 295 1.8E-61 T 13-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 THL1_RS01140 7f45198b009ee28a637ee16554e4436b 569 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 146 165 1.8E-61 T 13-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 THL1_RS01140 7f45198b009ee28a637ee16554e4436b 569 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 54 79 1.8E-61 T 13-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 THL1_RS01140 7f45198b009ee28a637ee16554e4436b 569 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 372 390 1.8E-61 T 13-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 THL1_RS01140 7f45198b009ee28a637ee16554e4436b 569 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 396 414 1.8E-61 T 13-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 THL1_RS01140 7f45198b009ee28a637ee16554e4436b 569 Pfam PF01019 Gamma-glutamyltranspeptidase 47 554 2.0E-152 T 13-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 THL1_RS01140 7f45198b009ee28a637ee16554e4436b 569 PANTHER PTHR11686:SF9 31 566 1.5E-175 T 13-09-2016 THL1_RS01140 7f45198b009ee28a637ee16554e4436b 569 SUPERFAMILY SSF56235 28 557 3.09E-148 T 13-09-2016 IPR029055 Nucleophile aminohydrolases, N-terminal THL1_RS01140 7f45198b009ee28a637ee16554e4436b 569 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 34 553 6.6E-113 T 13-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 THL1_RS01140 7f45198b009ee28a637ee16554e4436b 569 PANTHER PTHR11686 31 566 1.5E-175 T 13-09-2016 IPR000101 Gamma-glutamyltranspeptidase GO:0003840|GO:0006749 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 THL1_RS27805 f0d6041acb1c4787293617974b88f6c7 51 PANTHER PTHR15238 1 51 5.0E-24 T 13-09-2016 THL1_RS27805 f0d6041acb1c4787293617974b88f6c7 51 SUPERFAMILY SSF57829 1 49 1.04E-18 T 13-09-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 THL1_RS27805 f0d6041acb1c4787293617974b88f6c7 51 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 51 9.2E-25 T 13-09-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS27805 f0d6041acb1c4787293617974b88f6c7 51 Pfam PF00471 Ribosomal protein L33 4 49 7.1E-18 T 13-09-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS27805 f0d6041acb1c4787293617974b88f6c7 51 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 14.99 T 13-09-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS27805 f0d6041acb1c4787293617974b88f6c7 51 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 13-09-2016 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THL1_RS25975 c7054d52489d1b73c0e1d41b7d86e10e 205 Pfam PF05728 Uncharacterised protein family (UPF0227) 7 190 6.0E-61 T 13-09-2016 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA THL1_RS25975 c7054d52489d1b73c0e1d41b7d86e10e 205 SUPERFAMILY SSF53474 3 189 4.23E-19 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS25975 c7054d52489d1b73c0e1d41b7d86e10e 205 PANTHER PTHR35602:SF3 2 195 7.2E-91 T 13-09-2016 THL1_RS25975 c7054d52489d1b73c0e1d41b7d86e10e 205 PANTHER PTHR35602 2 195 7.2E-91 T 13-09-2016 THL1_RS25975 c7054d52489d1b73c0e1d41b7d86e10e 205 Gene3D G3DSA:3.40.50.1820 3 99 5.9E-19 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS25975 c7054d52489d1b73c0e1d41b7d86e10e 205 Gene3D G3DSA:3.40.50.1820 131 187 5.9E-19 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS21320 5dc77dbd5f63b511e1abe1da7328d0c2 316 PANTHER PTHR38782:SF1 1 313 1.5E-98 T 13-09-2016 THL1_RS21320 5dc77dbd5f63b511e1abe1da7328d0c2 316 Gene3D G3DSA:2.50.20.10 113 183 5.3E-9 T 13-09-2016 THL1_RS21320 5dc77dbd5f63b511e1abe1da7328d0c2 316 PIRSF PIRSF005427 1 314 6.7E-94 T 13-09-2016 IPR005588 MucB/RseB THL1_RS21320 5dc77dbd5f63b511e1abe1da7328d0c2 316 Pfam PF17188 MucB/RseB C-terminal domain 209 307 1.2E-26 T 13-09-2016 IPR033436 MucB/RseB, C-terminal THL1_RS21320 5dc77dbd5f63b511e1abe1da7328d0c2 316 PANTHER PTHR38782 1 313 1.5E-98 T 13-09-2016 THL1_RS21320 5dc77dbd5f63b511e1abe1da7328d0c2 316 Pfam PF03888 MucB/RseB N-terminal domain 22 194 1.2E-55 T 13-09-2016 IPR033434 MucB/RseB, N-terminal THL1_RS23585 1ce62ded66fb1ff6ebb7688e700632a9 153 SMART SM00086 80 122 6.3E-12 T 13-09-2016 IPR001610 PAC motif THL1_RS23585 1ce62ded66fb1ff6ebb7688e700632a9 153 SUPERFAMILY SSF55785 12 122 4.54E-29 T 13-09-2016 IPR000014 PAS domain THL1_RS23585 1ce62ded66fb1ff6ebb7688e700632a9 153 PANTHER PTHR24351 27 128 7.5E-32 T 13-09-2016 THL1_RS23585 1ce62ded66fb1ff6ebb7688e700632a9 153 Gene3D G3DSA:3.30.450.20 16 122 1.2E-33 T 13-09-2016 THL1_RS23585 1ce62ded66fb1ff6ebb7688e700632a9 153 SMART SM00091 5 74 2.1E-4 T 13-09-2016 IPR000014 PAS domain THL1_RS23585 1ce62ded66fb1ff6ebb7688e700632a9 153 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 5 128 7.5E-20 T 13-09-2016 IPR000014 PAS domain THL1_RS23585 1ce62ded66fb1ff6ebb7688e700632a9 153 Pfam PF13426 PAS domain 16 121 8.3E-23 T 13-09-2016 IPR000014 PAS domain THL1_RS18525 a0211bfe03160c17a429ba3e611b5226 250 Gene3D G3DSA:3.40.50.300 162 241 9.2E-23 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07900 e807bf5086e297786dd657252ce51a2b 472 PANTHER PTHR11699:SF108 13 469 4.8E-175 T 13-09-2016 THL1_RS07900 e807bf5086e297786dd657252ce51a2b 472 Gene3D G3DSA:3.40.605.10 16 258 3.6E-73 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS07900 e807bf5086e297786dd657252ce51a2b 472 Pfam PF00171 Aldehyde dehydrogenase family 15 466 1.3E-146 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS07900 e807bf5086e297786dd657252ce51a2b 472 Gene3D G3DSA:3.40.309.10 259 441 3.9E-61 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS07900 e807bf5086e297786dd657252ce51a2b 472 SUPERFAMILY SSF53720 14 470 2.23E-133 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS07900 e807bf5086e297786dd657252ce51a2b 472 PANTHER PTHR11699 13 469 4.8E-175 T 13-09-2016 THL1_RS26555 8eb71b397f494271d866cf9c69064951 195 Gene3D G3DSA:2.60.120.10 10 106 6.9E-38 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS26555 8eb71b397f494271d866cf9c69064951 195 Pfam PF05962 HutD 10 185 9.4E-55 T 13-09-2016 IPR010282 Uncharacterised protein family HutD/Ves THL1_RS26555 8eb71b397f494271d866cf9c69064951 195 PANTHER PTHR37943 2 170 1.8E-52 T 13-09-2016 THL1_RS26555 8eb71b397f494271d866cf9c69064951 195 Gene3D G3DSA:2.60.120.10 107 195 6.2E-35 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS26555 8eb71b397f494271d866cf9c69064951 195 PANTHER PTHR37943:SF1 2 170 1.8E-52 T 13-09-2016 THL1_RS26555 8eb71b397f494271d866cf9c69064951 195 SUPERFAMILY SSF51182 5 191 9.79E-58 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS15940 696f826d41a7696ce11e2645e7d5065e 397 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 188 202 - T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS15940 696f826d41a7696ce11e2645e7d5065e 397 SUPERFAMILY SSF52540 6 331 1.64E-66 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15940 696f826d41a7696ce11e2645e7d5065e 397 PANTHER PTHR30486 1 371 3.5E-147 T 13-09-2016 THL1_RS15940 696f826d41a7696ce11e2645e7d5065e 397 Gene3D G3DSA:3.40.50.300 96 338 2.0E-66 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15940 696f826d41a7696ce11e2645e7d5065e 397 PANTHER PTHR30486:SF3 1 371 3.5E-147 T 13-09-2016 THL1_RS15940 696f826d41a7696ce11e2645e7d5065e 397 SMART SM00382 117 242 0.0049 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS15940 696f826d41a7696ce11e2645e7d5065e 397 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 2 337 4.6E-131 T 13-09-2016 IPR006321 Pilus retraction protein PilT GO:0005524|GO:0006810 THL1_RS15940 696f826d41a7696ce11e2645e7d5065e 397 Pfam PF00437 Type II/IV secretion system protein 100 250 2.8E-38 T 13-09-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 THL1_RS20490 bb7b1fd41491be84142b81457f6de7db 817 Gene3D G3DSA:1.20.1640.10 600 795 6.2E-27 T 13-09-2016 THL1_RS20490 bb7b1fd41491be84142b81457f6de7db 817 Gene3D G3DSA:1.20.1640.10 214 400 2.8E-22 T 13-09-2016 THL1_RS20490 bb7b1fd41491be84142b81457f6de7db 817 PANTHER PTHR33406 143 787 1.4E-77 T 13-09-2016 THL1_RS20490 bb7b1fd41491be84142b81457f6de7db 817 PANTHER PTHR33406 16 118 1.4E-77 T 13-09-2016 THL1_RS20490 bb7b1fd41491be84142b81457f6de7db 817 SUPERFAMILY SSF82866 574 787 1.57E-29 T 13-09-2016 THL1_RS20490 bb7b1fd41491be84142b81457f6de7db 817 PANTHER PTHR33406:SF2 143 787 1.4E-77 T 13-09-2016 THL1_RS20490 bb7b1fd41491be84142b81457f6de7db 817 Pfam PF03176 MMPL family 489 786 9.3E-18 T 13-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 THL1_RS20490 bb7b1fd41491be84142b81457f6de7db 817 Pfam PF03176 MMPL family 79 422 3.9E-7 T 13-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 THL1_RS20490 bb7b1fd41491be84142b81457f6de7db 817 SUPERFAMILY SSF82866 209 398 6.93E-21 T 13-09-2016 THL1_RS20490 bb7b1fd41491be84142b81457f6de7db 817 PANTHER PTHR33406:SF2 16 118 1.4E-77 T 13-09-2016 THL1_RS03250 26bc1957c1e65576b85629659becc45b 145 SMART SM00347 27 128 4.1E-14 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS03250 26bc1957c1e65576b85629659becc45b 145 PANTHER PTHR33164:SF16 19 134 2.1E-23 T 13-09-2016 THL1_RS03250 26bc1957c1e65576b85629659becc45b 145 Pfam PF01047 MarR family 43 92 4.2E-11 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS03250 26bc1957c1e65576b85629659becc45b 145 Gene3D G3DSA:1.10.10.10 6 138 1.4E-28 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS03250 26bc1957c1e65576b85629659becc45b 145 SUPERFAMILY SSF46785 6 139 4.8E-26 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS03250 26bc1957c1e65576b85629659becc45b 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 2.9E-12 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS03250 26bc1957c1e65576b85629659becc45b 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 2.9E-12 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS03250 26bc1957c1e65576b85629659becc45b 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 2.9E-12 T 13-09-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THL1_RS03250 26bc1957c1e65576b85629659becc45b 145 PANTHER PTHR33164 19 134 2.1E-23 T 13-09-2016 THL1_RS02595 64cce71a7f50121fef43c3b279551ad4 275 Pfam PF00149 Calcineurin-like phosphoesterase 3 157 4.2E-13 T 13-09-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 THL1_RS02595 64cce71a7f50121fef43c3b279551ad4 275 Gene3D G3DSA:3.60.21.10 170 271 1.1E-54 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS02595 64cce71a7f50121fef43c3b279551ad4 275 Gene3D G3DSA:3.60.21.10 1 132 1.1E-54 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS02595 64cce71a7f50121fef43c3b279551ad4 275 PANTHER PTHR24032:SF27 1 266 6.1E-140 T 13-09-2016 THL1_RS02595 64cce71a7f50121fef43c3b279551ad4 275 PANTHER PTHR24032 1 266 6.1E-140 T 13-09-2016 THL1_RS02595 64cce71a7f50121fef43c3b279551ad4 275 SUPERFAMILY SSF56300 1 257 3.93E-57 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS02595 64cce71a7f50121fef43c3b279551ad4 275 PIRSF PIRSF000903 1 275 1.2E-118 T 13-09-2016 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 THL1_RS02595 64cce71a7f50121fef43c3b279551ad4 275 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 1 272 47.999 T 13-09-2016 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 THL1_RS02595 64cce71a7f50121fef43c3b279551ad4 275 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 1 260 4.4E-97 T 13-09-2016 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 THL1_RS11565 63900a93acfc7aa17cacd15783aa4024 255 SUPERFAMILY SSF53213 1 255 4.58E-94 T 13-09-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 THL1_RS11565 63900a93acfc7aa17cacd15783aa4024 255 Gene3D G3DSA:3.40.830.10 2 255 1.7E-97 T 13-09-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 THL1_RS11565 63900a93acfc7aa17cacd15783aa4024 255 PANTHER PTHR30096:SF0 1 254 1.6E-102 T 13-09-2016 THL1_RS11565 63900a93acfc7aa17cacd15783aa4024 255 PANTHER PTHR30096 1 254 1.6E-102 T 13-09-2016 THL1_RS11565 63900a93acfc7aa17cacd15783aa4024 255 PIRSF PIRSF006157 1 255 1.3E-92 T 13-09-2016 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA type GO:0008270|GO:0016701|GO:0055114 THL1_RS11565 63900a93acfc7aa17cacd15783aa4024 255 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 4 254 4.7E-52 T 13-09-2016 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 THL1_RS09325 aec2805495212a207ceecd6e6728b9b6 198 SMART SM01144 2 188 1.9E-69 T 13-09-2016 IPR005636 DTW THL1_RS09325 aec2805495212a207ceecd6e6728b9b6 198 Pfam PF03942 DTW domain 3 183 9.3E-50 T 13-09-2016 IPR005636 DTW THL1_RS09325 aec2805495212a207ceecd6e6728b9b6 198 PANTHER PTHR21392 3 196 3.0E-62 T 13-09-2016 THL1_RS05490 40619d8f6096fa72c22cd7b9fe183e45 207 PANTHER PTHR12277:SF79 15 203 3.7E-59 T 13-09-2016 THL1_RS05490 40619d8f6096fa72c22cd7b9fe183e45 207 PANTHER PTHR12277 15 203 3.7E-59 T 13-09-2016 THL1_RS05490 40619d8f6096fa72c22cd7b9fe183e45 207 Gene3D G3DSA:3.40.50.1820 24 204 2.2E-38 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS05490 40619d8f6096fa72c22cd7b9fe183e45 207 Pfam PF12146 Serine aminopeptidase, S33 55 138 7.3E-10 T 13-09-2016 IPR022742 Serine aminopeptidase, S33 THL1_RS05490 40619d8f6096fa72c22cd7b9fe183e45 207 SUPERFAMILY SSF53474 8 200 2.37E-37 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS20505 63b47e75186ac2a5676fa91700847089 546 Pfam PF06980 Protein of unknown function (DUF1302) 46 546 2.9E-93 T 13-09-2016 IPR010727 Protein of unknown function DUF1302 THL1_RS02760 463e2192000d3d2fd2b8af3b865ef4ff 322 Pfam PF06067 Domain of unknown function (DUF932) 77 302 3.9E-79 T 13-09-2016 IPR026325 Protein of unknown function DUF932 THL1_RS02760 463e2192000d3d2fd2b8af3b865ef4ff 322 TIGRFAM TIGR03299 LGT_TIGR03299: phage/plasmid-like protein TIGR03299 6 318 2.7E-117 T 13-09-2016 IPR017686 Phage/plasmid-like protein THL1_RS06285 e9cdd15572d939734dfd93be10fbf4cc 471 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 60 321 4.9E-84 T 13-09-2016 IPR031811 AlgX, SGNH hydrolase-like domain KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.-|UniPathway: UPA00286 THL1_RS06285 e9cdd15572d939734dfd93be10fbf4cc 471 Pfam PF16824 C-terminal carbohydrate-binding module 342 458 3.0E-51 T 13-09-2016 IPR031798 Alginate biosynthesis protein AlgX, C-terminal carbohydrate-binding module KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.-|UniPathway: UPA00286 THL1_RS18970 0d5d83d0f10d0dd77dbff9dc47e4232c 244 PIRSF PIRSF039085 1 243 8.4E-102 T 13-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 THL1_RS18970 0d5d83d0f10d0dd77dbff9dc47e4232c 244 Gene3D G3DSA:3.40.50.300 1 226 2.6E-79 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18970 0d5d83d0f10d0dd77dbff9dc47e4232c 244 SUPERFAMILY SSF52540 1 226 4.31E-76 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18970 0d5d83d0f10d0dd77dbff9dc47e4232c 244 PANTHER PTHR24220:SF317 3 244 5.1E-185 T 13-09-2016 IPR030206 Glutamate/aspartate transport ATP-binding protein GltL/AatP GO:0005524|GO:0006865|GO:0043190 THL1_RS18970 0d5d83d0f10d0dd77dbff9dc47e4232c 244 PANTHER PTHR24220 3 244 5.1E-185 T 13-09-2016 THL1_RS18970 0d5d83d0f10d0dd77dbff9dc47e4232c 244 SMART SM00382 26 213 4.9E-18 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS18970 0d5d83d0f10d0dd77dbff9dc47e4232c 244 Pfam PF00005 ABC transporter 17 165 5.0E-35 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS18970 0d5d83d0f10d0dd77dbff9dc47e4232c 244 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS21190 9306042f118dccdb10678228e1c38121 340 PANTHER PTHR30420 1 340 4.0E-182 T 13-09-2016 THL1_RS21190 9306042f118dccdb10678228e1c38121 340 Gene3D G3DSA:3.40.630.30 1 77 3.0E-5 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS21190 9306042f118dccdb10678228e1c38121 340 Pfam PF04958 Arginine N-succinyltransferase beta subunit 1 333 2.3E-133 T 13-09-2016 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109|UniPathway: UPA00185 THL1_RS21190 9306042f118dccdb10678228e1c38121 340 TIGRFAM TIGR03243 arg_catab_AOST: arginine and ornithine succinyltransferase subunits 2 334 2.6E-142 T 13-09-2016 IPR007041 Arginine N-succinyltransferase AstA/AruG GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109|UniPathway: UPA00185 THL1_RS21190 9306042f118dccdb10678228e1c38121 340 TIGRFAM TIGR03244 arg_catab_AstA: arginine N-succinyltransferase 2 334 7.9E-154 T 13-09-2016 IPR017650 Arginine N-succinyltransferase GO:0006527|GO:0008791 KEGG: 00330+2.3.1.109|UniPathway: UPA00185 THL1_RS21190 9306042f118dccdb10678228e1c38121 340 Gene3D G3DSA:2.40.40.20 278 334 1.9E-6 T 13-09-2016 THL1_RS21190 9306042f118dccdb10678228e1c38121 340 SUPERFAMILY SSF55729 1 334 9.1E-126 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS21190 9306042f118dccdb10678228e1c38121 340 PANTHER PTHR30420:SF1 1 340 4.0E-182 T 13-09-2016 THL1_RS04060 3271859afe982e6482e66bccb6049c52 272 PANTHER PTHR30164 1 271 3.5E-100 T 13-09-2016 THL1_RS04060 3271859afe982e6482e66bccb6049c52 272 Pfam PF06167 Glucose-regulated metallo-peptidase M90 5 249 2.7E-89 T 13-09-2016 IPR010384 MtfA family THL1_RS04060 3271859afe982e6482e66bccb6049c52 272 Gene3D G3DSA:3.40.390.10 35 250 9.1E-32 T 13-09-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 THL1_RS04060 3271859afe982e6482e66bccb6049c52 272 SUPERFAMILY SSF55486 40 251 2.12E-36 T 13-09-2016 THL1_RS17110 8186846a8fc6af3de60d9586e2e61d28 368 Gene3D G3DSA:2.40.160.10 228 325 5.5E-6 T 13-09-2016 IPR023614 Porin domain THL1_RS17110 8186846a8fc6af3de60d9586e2e61d28 368 Pfam PF13609 Gram-negative porin 11 321 3.0E-7 T 13-09-2016 THL1_RS17110 8186846a8fc6af3de60d9586e2e61d28 368 SUPERFAMILY SSF56935 354 368 4.88E-24 T 13-09-2016 THL1_RS17110 8186846a8fc6af3de60d9586e2e61d28 368 SUPERFAMILY SSF56935 2 326 4.88E-24 T 13-09-2016 THL1_RS27875 66c6ae2550a8ad8f8a39ff44a5e26eaa 287 Pfam PF08340 Domain of unknown function (DUF1732) 203 287 2.0E-34 T 13-09-2016 IPR013551 Domain of unknown function DUF1732 THL1_RS27875 66c6ae2550a8ad8f8a39ff44a5e26eaa 287 PANTHER PTHR30636 1 287 6.2E-103 T 13-09-2016 THL1_RS27875 66c6ae2550a8ad8f8a39ff44a5e26eaa 287 Pfam PF03755 YicC-like family, N-terminal region 2 153 2.7E-40 T 13-09-2016 IPR013527 YicC-like, N-terminal THL1_RS27875 66c6ae2550a8ad8f8a39ff44a5e26eaa 287 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 287 3.1E-91 T 13-09-2016 IPR005229 Conserved hypothetical protein CHP00255 THL1_RS10350 7558dbf9f0f50b8a3336f9ba743fc97b 71 Gene3D G3DSA:1.10.10.620 1 65 1.9E-30 T 13-09-2016 IPR023200 Ribosome modulation factor-like domain THL1_RS10350 7558dbf9f0f50b8a3336f9ba743fc97b 71 ProDom PD051650 RIBOSOME MODULATION FACTOR E FACTOR-RELATED DIMERIZATION BIOGENESIS RIBOSOMES INVOLVED 70S 1 50 1.0E-21 T 13-09-2016 IPR007040 Ribosome modulation factor THL1_RS10350 7558dbf9f0f50b8a3336f9ba743fc97b 71 Hamap MF_00919 Ribosome modulation factor [rmf]. 1 55 28.125 T 13-09-2016 IPR007040 Ribosome modulation factor THL1_RS10350 7558dbf9f0f50b8a3336f9ba743fc97b 71 Pfam PF04957 Ribosome modulation factor 1 54 7.1E-26 T 13-09-2016 IPR007040 Ribosome modulation factor THL1_RS13290 56e5abb2c266bec6067f77784fb48e7e 167 Pfam PF00011 Hsp20/alpha crystallin family 67 164 6.5E-19 T 13-09-2016 IPR002068 Alpha crystallin/Hsp20 domain THL1_RS13290 56e5abb2c266bec6067f77784fb48e7e 167 PANTHER PTHR11527:SF122 65 166 4.5E-28 T 13-09-2016 THL1_RS13290 56e5abb2c266bec6067f77784fb48e7e 167 SUPERFAMILY SSF49764 47 164 1.59E-31 T 13-09-2016 IPR008978 HSP20-like chaperone THL1_RS13290 56e5abb2c266bec6067f77784fb48e7e 167 PANTHER PTHR11527 65 166 4.5E-28 T 13-09-2016 IPR031107 Small heat shock protein HSP20 THL1_RS13290 56e5abb2c266bec6067f77784fb48e7e 167 Gene3D G3DSA:2.60.40.790 26 165 3.5E-31 T 13-09-2016 IPR008978 HSP20-like chaperone THL1_RS17340 b9ef7756f4c30e94ca1fed718d6328c4 78 Pfam PF10038 Protein of unknown function (DUF2274) 4 69 3.1E-25 T 13-09-2016 IPR018733 Protein of unknown function DUF2274 THL1_RS14470 aa14c90feccdc055490d077525645bea 247 SUPERFAMILY SSF89733 1 134 2.09E-8 T 13-09-2016 IPR003767 Malate/L-lactate dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS14470 aa14c90feccdc055490d077525645bea 247 Pfam PF12525 Protein of unknown function (DUF3726) 4 65 2.9E-14 T 13-09-2016 IPR022201 Protein of unknown function DUF3726 THL1_RS20285 104c4fe79d65c3dc3ffd1af63f3edc0f 376 PANTHER PTHR13847 4 230 9.5E-19 T 13-09-2016 THL1_RS20285 104c4fe79d65c3dc3ffd1af63f3edc0f 376 Gene3D G3DSA:3.50.50.60 5 83 2.7E-27 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20285 104c4fe79d65c3dc3ffd1af63f3edc0f 376 Gene3D G3DSA:3.50.50.60 337 370 2.7E-27 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20285 104c4fe79d65c3dc3ffd1af63f3edc0f 376 Gene3D G3DSA:3.50.50.60 137 214 2.7E-27 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20285 104c4fe79d65c3dc3ffd1af63f3edc0f 376 Pfam PF01266 FAD dependent oxidoreductase 7 370 4.3E-38 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS20285 104c4fe79d65c3dc3ffd1af63f3edc0f 376 SUPERFAMILY SSF51905 6 215 2.72E-32 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20285 104c4fe79d65c3dc3ffd1af63f3edc0f 376 SUPERFAMILY SSF51905 337 370 2.72E-32 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS20285 104c4fe79d65c3dc3ffd1af63f3edc0f 376 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 6 369 2.7E-137 T 13-09-2016 IPR017741 FAD-dependent oxidoreductase, HpnW THL1_RS13480 31ece71ef4992bdcb4c2222caac6f3ff 331 Gene3D G3DSA:3.90.850.10 133 310 1.2E-7 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS13480 31ece71ef4992bdcb4c2222caac6f3ff 331 PIRSF PIRSF033905 1 331 3.2E-166 T 13-09-2016 IPR009645 Uncharacterised conserved protein GguC THL1_RS13480 31ece71ef4992bdcb4c2222caac6f3ff 331 SUPERFAMILY SSF56529 114 315 6.15E-27 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS23910 843e28d771f942d4d5a2858fd3e3b323 321 PANTHER PTHR30087:SF0 2 321 2.7E-136 T 13-09-2016 THL1_RS23910 843e28d771f942d4d5a2858fd3e3b323 321 Pfam PF08349 Protein of unknown function (DUF1722) 196 312 1.7E-41 T 13-09-2016 IPR013560 Domain of unknown function DUF1722 THL1_RS23910 843e28d771f942d4d5a2858fd3e3b323 321 PIRSF PIRSF037004 6 321 2.0E-130 T 13-09-2016 IPR017087 Uncharacterised conserved protein UCP037004 THL1_RS23910 843e28d771f942d4d5a2858fd3e3b323 321 Pfam PF04463 Protein of unknown function (DUF523) 14 153 2.3E-35 T 13-09-2016 IPR007553 Domain of unknown function DUF523 THL1_RS23910 843e28d771f942d4d5a2858fd3e3b323 321 PANTHER PTHR30087 2 321 2.7E-136 T 13-09-2016 THL1_RS04190 b501aa170683a4a1880fb3249a0d4802 438 SUPERFAMILY SSF48317 213 398 1.44E-40 T 13-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THL1_RS04190 b501aa170683a4a1880fb3249a0d4802 438 Pfam PF01569 PAP2 superfamily 286 395 1.2E-19 T 13-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THL1_RS04190 b501aa170683a4a1880fb3249a0d4802 438 PANTHER PTHR30353:SF5 1 415 7.7E-182 T 13-09-2016 THL1_RS04190 b501aa170683a4a1880fb3249a0d4802 438 Gene3D G3DSA:1.20.144.10 211 405 2.9E-35 T 13-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THL1_RS04190 b501aa170683a4a1880fb3249a0d4802 438 SMART SM00014 283 393 4.5E-16 T 13-09-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THL1_RS04190 b501aa170683a4a1880fb3249a0d4802 438 PANTHER PTHR30353 1 415 7.7E-182 T 13-09-2016 IPR032818 DedA family THL1_RS04190 b501aa170683a4a1880fb3249a0d4802 438 Pfam PF09335 SNARE associated Golgi protein 39 162 6.8E-19 T 13-09-2016 IPR032816 SNARE associated Golgi protein THL1_RS10840 db1124ccbe5a5dfa702d05d18f63c1e3 200 Pfam PF01852 START domain 14 200 9.9E-11 T 13-09-2016 IPR002913 START domain GO:0008289 THL1_RS10840 db1124ccbe5a5dfa702d05d18f63c1e3 200 SUPERFAMILY SSF55961 18 199 2.07E-38 T 13-09-2016 THL1_RS10840 db1124ccbe5a5dfa702d05d18f63c1e3 200 PANTHER PTHR19308:SF1 13 199 1.5E-83 T 13-09-2016 THL1_RS10840 db1124ccbe5a5dfa702d05d18f63c1e3 200 Gene3D G3DSA:3.30.530.20 3 198 5.1E-37 T 13-09-2016 IPR023393 START-like domain THL1_RS10840 db1124ccbe5a5dfa702d05d18f63c1e3 200 PANTHER PTHR19308 13 199 1.5E-83 T 13-09-2016 THL1_RS10840 db1124ccbe5a5dfa702d05d18f63c1e3 200 PIRSF PIRSF039033 1 200 7.1E-71 T 13-09-2016 IPR028347 START domain-containing protein THL1_RS01205 49e33f94e6bc8abc4de6cd1dde6151eb 339 PIRSF PIRSF003097 41 335 2.8E-66 T 13-09-2016 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 THL1_RS01205 49e33f94e6bc8abc4de6cd1dde6151eb 339 Pfam PF02687 FtsX-like permease family 215 331 3.7E-9 T 13-09-2016 IPR003838 ABC transporter permease protein domain GO:0016020 THL1_RS11415 a1e3ad0940247396fdcafd10c6ab4fe2 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 13-09-2016 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 THL1_RS11415 a1e3ad0940247396fdcafd10c6ab4fe2 257 SUPERFAMILY SSF52096 1 256 9.39E-91 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS11415 a1e3ad0940247396fdcafd10c6ab4fe2 257 PANTHER PTHR11941 1 254 8.3E-121 T 13-09-2016 THL1_RS11415 a1e3ad0940247396fdcafd10c6ab4fe2 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 256 1.4E-79 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS11415 a1e3ad0940247396fdcafd10c6ab4fe2 257 Gene3D G3DSA:3.90.226.10 1 254 5.0E-100 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS11415 a1e3ad0940247396fdcafd10c6ab4fe2 257 PANTHER PTHR11941:SF54 1 254 8.3E-121 T 13-09-2016 THL1_RS14370 396e9e27f0750652a2fd23a5336a1442 309 PANTHER PTHR36838 1 309 1.9E-32 T 13-09-2016 THL1_RS14370 396e9e27f0750652a2fd23a5336a1442 309 Pfam PF03547 Membrane transport protein 163 301 1.9E-9 T 13-09-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 THL1_RS14370 396e9e27f0750652a2fd23a5336a1442 309 Pfam PF03547 Membrane transport protein 9 144 3.4E-11 T 13-09-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 THL1_RS15780 beb7addc443925bb272d010b0ae73a33 686 Pfam PF01575 MaoC like domain 543 645 3.0E-29 T 13-09-2016 IPR002539 MaoC-like domain THL1_RS15780 beb7addc443925bb272d010b0ae73a33 686 PANTHER PTHR11699:SF12 1 524 2.0E-138 T 13-09-2016 IPR011966 Phenylacetic acid degradation protein PaaN THL1_RS15780 beb7addc443925bb272d010b0ae73a33 686 Pfam PF00171 Aldehyde dehydrogenase family 26 502 1.1E-57 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS15780 beb7addc443925bb272d010b0ae73a33 686 Gene3D G3DSA:3.40.309.10 268 458 3.0E-38 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS15780 beb7addc443925bb272d010b0ae73a33 686 SUPERFAMILY SSF53720 6 507 1.18E-76 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS15780 beb7addc443925bb272d010b0ae73a33 686 SUPERFAMILY SSF54637 532 684 3.87E-40 T 13-09-2016 IPR029069 HotDog domain THL1_RS15780 beb7addc443925bb272d010b0ae73a33 686 TIGRFAM TIGR02278 PaaN-DH: phenylacetic acid degradation protein paaN 7 680 1.3E-302 T 13-09-2016 IPR011966 Phenylacetic acid degradation protein PaaN THL1_RS15780 beb7addc443925bb272d010b0ae73a33 686 Gene3D G3DSA:3.40.605.10 6 267 2.3E-33 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS15780 beb7addc443925bb272d010b0ae73a33 686 Gene3D G3DSA:3.10.129.10 527 683 5.0E-48 T 13-09-2016 IPR029069 HotDog domain THL1_RS15780 beb7addc443925bb272d010b0ae73a33 686 PANTHER PTHR11699 1 524 2.0E-138 T 13-09-2016 THL1_RS21360 24bd088cb2ccefaf49317802aa0f77a1 251 PANTHER PTHR35936 1 238 1.5E-47 T 13-09-2016 THL1_RS21360 24bd088cb2ccefaf49317802aa0f77a1 251 Gene3D G3DSA:3.40.190.10 94 181 7.8E-9 T 13-09-2016 THL1_RS21360 24bd088cb2ccefaf49317802aa0f77a1 251 PANTHER PTHR35936:SF3 1 238 1.5E-47 T 13-09-2016 THL1_RS21360 24bd088cb2ccefaf49317802aa0f77a1 251 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 238 3.2E-13 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS21360 24bd088cb2ccefaf49317802aa0f77a1 251 SUPERFAMILY SSF53850 18 239 1.18E-32 T 13-09-2016 THL1_RS21360 24bd088cb2ccefaf49317802aa0f77a1 251 Gene3D G3DSA:3.40.190.10 38 93 7.3E-4 T 13-09-2016 THL1_RS21360 24bd088cb2ccefaf49317802aa0f77a1 251 Gene3D G3DSA:3.40.190.10 203 238 7.3E-4 T 13-09-2016 THL1_RS26665 137808b6a545b7ad77f00c74d2ab8a15 170 Pfam PF13511 Domain of unknown function (DUF4124) 8 60 1.2E-16 T 13-09-2016 IPR025392 Domain of unknown function DUF4124 THL1_RS17030 21c5631801976afaa4eb7ec4cab95a75 80 Gene3D G3DSA:1.10.1220.10 32 73 3.8E-8 T 13-09-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THL1_RS17030 21c5631801976afaa4eb7ec4cab95a75 80 SUPERFAMILY SSF47598 33 77 1.33E-9 T 13-09-2016 IPR010985 Ribbon-helix-helix GO:0006355 THL1_RS02745 c9a5fcee55a7e06413f2b120022c5f51 165 PANTHER PTHR30471 26 165 1.3E-68 T 13-09-2016 THL1_RS02745 c9a5fcee55a7e06413f2b120022c5f51 165 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 114 119 - T 13-09-2016 IPR020891 Uncharacterised protein family UPF0758, conserved site THL1_RS02745 c9a5fcee55a7e06413f2b120022c5f51 165 Pfam PF04002 RadC-like JAB domain 44 163 1.6E-43 T 13-09-2016 IPR025657 RadC-like JAB domain THL1_RS02745 c9a5fcee55a7e06413f2b120022c5f51 165 PANTHER PTHR30471:SF5 26 165 1.3E-68 T 13-09-2016 THL1_RS02745 c9a5fcee55a7e06413f2b120022c5f51 165 SUPERFAMILY SSF102712 55 141 4.32E-7 T 13-09-2016 THL1_RS02745 c9a5fcee55a7e06413f2b120022c5f51 165 Gene3D G3DSA:3.40.140.10 42 165 5.9E-48 T 13-09-2016 THL1_RS02745 c9a5fcee55a7e06413f2b120022c5f51 165 TIGRFAM TIGR00608 radc: DNA repair protein RadC 28 165 2.5E-43 T 13-09-2016 IPR001405 RadC protein THL1_RS16195 492b02faf68ee2561a9933c772e1b618 79 SUPERFAMILY SSF47598 1 42 1.56E-6 T 13-09-2016 IPR010985 Ribbon-helix-helix GO:0006355 THL1_RS24235 cbd57e6d38a88b9ed9012f715cfd94d7 294 SUPERFAMILY SSF159501 33 274 2.46E-68 T 13-09-2016 THL1_RS24235 cbd57e6d38a88b9ed9012f715cfd94d7 294 PIRSF PIRSF020419 1 288 2.1E-107 T 13-09-2016 IPR016773 Ferric uptake regulator, CjrA, predicted THL1_RS24235 cbd57e6d38a88b9ed9012f715cfd94d7 294 Pfam PF04187 Haem-binding uptake, Tiki superfamily, ChaN 52 242 5.2E-45 T 13-09-2016 IPR007314 Haem-binding uptake, Tiki superfamily, ChaN THL1_RS15175 842d8e9a244a8fc60ce6c5628c0c9505 112 Pfam PF10734 Protein of unknown function (DUF2523) 33 103 2.5E-10 T 13-09-2016 IPR019670 Protein of unkown function DUF2523 THL1_RS15275 842d8e9a244a8fc60ce6c5628c0c9505 112 Pfam PF10734 Protein of unknown function (DUF2523) 33 103 2.5E-10 T 13-09-2016 IPR019670 Protein of unkown function DUF2523 THL1_RS14220 0cdc06c63c24f1f2ff1ebeacc6cacd30 145 SUPERFAMILY SSF46626 50 138 3.67E-18 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS14220 0cdc06c63c24f1f2ff1ebeacc6cacd30 145 Gene3D G3DSA:1.10.760.10 53 141 4.3E-19 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS14220 0cdc06c63c24f1f2ff1ebeacc6cacd30 145 TIGRFAM TIGR04494 c550_PedF: cytochrome c-550 PedF 12 143 4.8E-63 T 13-09-2016 IPR030991 Cytochrome c-550 PedF THL1_RS14220 0cdc06c63c24f1f2ff1ebeacc6cacd30 145 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 62 138 7.2E-14 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS26870 f6143fbe3ad1a2eb6653b83299ef6079 204 Gene3D G3DSA:1.10.10.10 65 105 2.8E-8 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS26870 f6143fbe3ad1a2eb6653b83299ef6079 204 SUPERFAMILY SSF46785 65 108 1.65E-8 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS26870 f6143fbe3ad1a2eb6653b83299ef6079 204 Pfam PF13730 Helix-turn-helix domain 36 89 3.5E-8 T 13-09-2016 THL1_RS23180 a36bf10e56e3555c74e9ef59d214bdd4 507 Gene3D G3DSA:3.20.130.10 305 487 8.3E-73 T 13-09-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 THL1_RS23180 a36bf10e56e3555c74e9ef59d214bdd4 507 SUPERFAMILY SSF117457 318 487 3.01E-63 T 13-09-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 THL1_RS23180 a36bf10e56e3555c74e9ef59d214bdd4 507 Pfam PF05681 Fumarate hydratase (Fumerase) 11 285 2.3E-101 T 13-09-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 THL1_RS23180 a36bf10e56e3555c74e9ef59d214bdd4 507 PANTHER PTHR30389 1 507 0.0 T 13-09-2016 THL1_RS23180 a36bf10e56e3555c74e9ef59d214bdd4 507 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 12 286 8.7E-66 T 13-09-2016 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 THL1_RS23180 a36bf10e56e3555c74e9ef59d214bdd4 507 PANTHER PTHR30389:SF1 1 507 0.0 T 13-09-2016 THL1_RS23180 a36bf10e56e3555c74e9ef59d214bdd4 507 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 325 486 6.5E-49 T 13-09-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 THL1_RS23180 a36bf10e56e3555c74e9ef59d214bdd4 507 Pfam PF05683 Fumarase C-terminus 289 488 9.0E-80 T 13-09-2016 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 THL1_RS23180 a36bf10e56e3555c74e9ef59d214bdd4 507 PIRSF PIRSF001394 1 506 2.1E-224 T 13-09-2016 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|UniPathway: UPA00223 THL1_RS25055 c846aaddd32412f78e7d27aa8b3eb750 88 Pfam PF13670 Peptidase propeptide and YPEB domain 4 85 2.6E-30 T 13-09-2016 IPR025711 PepSY domain THL1_RS17005 814be7aa8e9c5b6675649020c2390941 170 Pfam PF07275 Antirestriction protein (ArdA) 7 161 3.4E-42 T 13-09-2016 IPR009899 Antirestriction THL1_RS26120 273c2605da9adfa49f9bc2c4dd00b180 200 PANTHER PTHR23416 70 196 2.4E-31 T 13-09-2016 THL1_RS26120 273c2605da9adfa49f9bc2c4dd00b180 200 SUPERFAMILY SSF51161 56 197 3.88E-34 T 13-09-2016 IPR011004 Trimeric LpxA-like THL1_RS26120 273c2605da9adfa49f9bc2c4dd00b180 200 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 145 178 6.0E-10 T 13-09-2016 IPR001451 Hexapeptide repeat THL1_RS26120 273c2605da9adfa49f9bc2c4dd00b180 200 Gene3D G3DSA:2.160.10.10 84 198 4.7E-36 T 13-09-2016 THL1_RS26120 273c2605da9adfa49f9bc2c4dd00b180 200 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 153 181 - T 13-09-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 THL1_RS17780 d99c7e21ed7c41ffb262f3ee4f751584 166 PIRSF PIRSF030820 1 166 2.4E-61 T 13-09-2016 IPR008318 Uncharacterised conserved protein UCP030820 THL1_RS17780 d99c7e21ed7c41ffb262f3ee4f751584 166 Pfam PF06073 Bacterial protein of unknown function (DUF934) 55 161 4.1E-42 T 13-09-2016 IPR008318 Uncharacterised conserved protein UCP030820 THL1_RS01300 18ca61613dbab77c8e16471717ebf43e 272 PANTHER PTHR11645:SF0 1 272 5.6E-112 T 13-09-2016 THL1_RS01300 18ca61613dbab77c8e16471717ebf43e 272 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 162 266 2.4E-35 T 13-09-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 THL1_RS01300 18ca61613dbab77c8e16471717ebf43e 272 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 5 99 1.2E-22 T 13-09-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal THL1_RS01300 18ca61613dbab77c8e16471717ebf43e 272 PANTHER PTHR11645 1 272 5.6E-112 T 13-09-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 THL1_RS01300 18ca61613dbab77c8e16471717ebf43e 272 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 6 266 1.2E-77 T 13-09-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 THL1_RS01300 18ca61613dbab77c8e16471717ebf43e 272 SUPERFAMILY SSF48179 161 269 4.25E-34 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS01300 18ca61613dbab77c8e16471717ebf43e 272 SUPERFAMILY SSF51735 5 159 3.86E-39 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS01300 18ca61613dbab77c8e16471717ebf43e 272 PIRSF PIRSF000193 3 269 3.3E-79 T 13-09-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 THL1_RS01300 18ca61613dbab77c8e16471717ebf43e 272 Gene3D G3DSA:3.40.50.720 3 158 2.6E-47 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS01300 18ca61613dbab77c8e16471717ebf43e 272 Gene3D G3DSA:1.10.3730.10 161 266 2.5E-36 T 13-09-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 THL1_RS01300 18ca61613dbab77c8e16471717ebf43e 272 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 222 244 - T 13-09-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 THL1_RS01300 18ca61613dbab77c8e16471717ebf43e 272 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 4 266 26.823 T 13-09-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 THL1_RS28205 69eb3876d71a13a0692aff1f10768b39 428 PANTHER PTHR13847:SF190 1 407 3.9E-110 T 13-09-2016 THL1_RS28205 69eb3876d71a13a0692aff1f10768b39 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 33 55 2.3E-5 T 13-09-2016 THL1_RS28205 69eb3876d71a13a0692aff1f10768b39 428 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 313 2.3E-5 T 13-09-2016 THL1_RS28205 69eb3876d71a13a0692aff1f10768b39 428 Pfam PF01266 FAD dependent oxidoreductase 33 386 1.3E-60 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS28205 69eb3876d71a13a0692aff1f10768b39 428 SUPERFAMILY SSF51905 32 257 2.81E-47 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS28205 69eb3876d71a13a0692aff1f10768b39 428 SUPERFAMILY SSF51905 349 411 2.81E-47 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS28205 69eb3876d71a13a0692aff1f10768b39 428 Gene3D G3DSA:3.50.50.60 21 122 1.5E-47 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS28205 69eb3876d71a13a0692aff1f10768b39 428 Gene3D G3DSA:3.50.50.60 175 256 1.5E-47 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS28205 69eb3876d71a13a0692aff1f10768b39 428 Gene3D G3DSA:3.50.50.60 349 401 1.5E-47 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS28205 69eb3876d71a13a0692aff1f10768b39 428 PANTHER PTHR13847 1 407 3.9E-110 T 13-09-2016 THL1_RS16040 aca7ddba08f2b2b0cdce0e6403973284 169 SUPERFAMILY SSF48452 35 107 4.01E-9 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS16040 aca7ddba08f2b2b0cdce0e6403973284 169 Gene3D G3DSA:1.25.40.10 36 107 6.9E-9 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS26080 2eb842977cdb04160873f5bcbc6955d0 478 PANTHER PTHR12993 311 390 8.8E-42 T 13-09-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related THL1_RS26080 2eb842977cdb04160873f5bcbc6955d0 478 PANTHER PTHR12993 137 274 8.8E-42 T 13-09-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related THL1_RS26080 2eb842977cdb04160873f5bcbc6955d0 478 Pfam PF02585 GlcNAc-PI de-N-acetylase 185 353 7.5E-12 T 13-09-2016 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related THL1_RS26080 2eb842977cdb04160873f5bcbc6955d0 478 SUPERFAMILY SSF102588 182 446 8.5E-28 T 13-09-2016 IPR024078 Putative deacetylase LmbE-like domain THL1_RS26080 2eb842977cdb04160873f5bcbc6955d0 478 PANTHER PTHR12993:SF10 311 390 8.8E-42 T 13-09-2016 THL1_RS26080 2eb842977cdb04160873f5bcbc6955d0 478 PANTHER PTHR12993:SF10 137 274 8.8E-42 T 13-09-2016 THL1_RS26080 2eb842977cdb04160873f5bcbc6955d0 478 Gene3D G3DSA:3.40.50.10320 309 382 2.8E-21 T 13-09-2016 IPR024078 Putative deacetylase LmbE-like domain THL1_RS26080 2eb842977cdb04160873f5bcbc6955d0 478 Gene3D G3DSA:3.40.50.10320 182 269 2.8E-21 T 13-09-2016 IPR024078 Putative deacetylase LmbE-like domain THL1_RS05785 b9212c85faa4e8f870c4cdb1b8294a48 95 PANTHER PTHR34477 7 89 7.2E-36 T 13-09-2016 THL1_RS05785 b9212c85faa4e8f870c4cdb1b8294a48 95 PANTHER PTHR34477:SF1 7 89 7.2E-36 T 13-09-2016 THL1_RS05785 b9212c85faa4e8f870c4cdb1b8294a48 95 Pfam PF01541 GIY-YIG catalytic domain 14 83 2.1E-13 T 13-09-2016 IPR000305 GIY-YIG nuclease superfamily THL1_RS05785 b9212c85faa4e8f870c4cdb1b8294a48 95 SUPERFAMILY SSF82771 13 83 5.36E-12 T 13-09-2016 IPR000305 GIY-YIG nuclease superfamily THL1_RS23470 b928d2ee68a9cd73d839b5760081d5f2 169 Pfam PF11454 Protein of unknown function (DUF3016) 23 157 3.6E-44 T 13-09-2016 IPR021557 Protein of unknown function DUF3016 THL1_RS11105 4ae94a39919efe920de75998778729d5 456 PANTHER PTHR33408:SF2 1 448 4.6E-23 T 13-09-2016 THL1_RS11105 4ae94a39919efe920de75998778729d5 456 PANTHER PTHR33408 1 448 4.6E-23 T 13-09-2016 THL1_RS11105 4ae94a39919efe920de75998778729d5 456 Pfam PF13751 Transposase DDE domain 319 444 4.3E-17 T 13-09-2016 IPR025668 Transposase DDE domain THL1_RS11105 4ae94a39919efe920de75998778729d5 456 Pfam PF05598 Transposase domain (DUF772) 52 128 1.0E-26 T 13-09-2016 IPR008490 Transposase InsH, N-terminal THL1_RS17770 3b28475990a55f62a1f46e196727a349 361 PANTHER PTHR32196 35 276 8.4E-12 T 13-09-2016 THL1_RS17770 3b28475990a55f62a1f46e196727a349 361 PANTHER PTHR32196:SF9 35 276 8.4E-12 T 13-09-2016 THL1_RS17770 3b28475990a55f62a1f46e196727a349 361 Pfam PF13407 Periplasmic binding protein domain 25 294 3.7E-25 T 13-09-2016 IPR025997 Periplasmic binding protein THL1_RS17770 3b28475990a55f62a1f46e196727a349 361 SUPERFAMILY SSF53822 25 298 1.94E-47 T 13-09-2016 IPR028082 Periplasmic binding protein-like I THL1_RS17770 3b28475990a55f62a1f46e196727a349 361 Gene3D G3DSA:3.40.50.2300 149 301 4.0E-29 T 13-09-2016 THL1_RS17770 3b28475990a55f62a1f46e196727a349 361 Gene3D G3DSA:3.40.50.2300 28 148 3.3E-11 T 13-09-2016 THL1_RS05775 5f8b446cfee503974816401e69ac0a97 210 Pfam PF13309 HTH domain 142 203 6.9E-17 T 13-09-2016 THL1_RS05775 5f8b446cfee503974816401e69ac0a97 210 PANTHER PTHR35568:SF1 1 210 2.9E-83 T 13-09-2016 THL1_RS05775 5f8b446cfee503974816401e69ac0a97 210 Gene3D G3DSA:1.10.10.10 159 208 6.0E-4 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS05775 5f8b446cfee503974816401e69ac0a97 210 PANTHER PTHR35568 1 210 2.9E-83 T 13-09-2016 THL1_RS05775 5f8b446cfee503974816401e69ac0a97 210 Pfam PF08348 YheO-like PAS domain 9 114 3.5E-26 T 13-09-2016 IPR013559 YheO-like THL1_RS05775 5f8b446cfee503974816401e69ac0a97 210 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 6 113 5.0E-49 T 13-09-2016 IPR013559 YheO-like THL1_RS07480 cdf2ff100f184d81f3c702d1bc2ceeb0 781 Pfam PF09347 Domain of unknown function (DUF1989) 184 352 1.2E-44 T 13-09-2016 IPR018959 Domain of unknown function DUF1989 THL1_RS07480 cdf2ff100f184d81f3c702d1bc2ceeb0 781 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 675 766 1.5E-19 T 13-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS07480 cdf2ff100f184d81f3c702d1bc2ceeb0 781 Gene3D G3DSA:3.30.70.1400 454 535 6.3E-17 T 13-09-2016 THL1_RS07480 cdf2ff100f184d81f3c702d1bc2ceeb0 781 Gene3D G3DSA:3.30.1360.120 540 643 9.9E-24 T 13-09-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THL1_RS07480 cdf2ff100f184d81f3c702d1bc2ceeb0 781 SUPERFAMILY SSF101790 691 780 1.8E-18 T 13-09-2016 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain THL1_RS07480 cdf2ff100f184d81f3c702d1bc2ceeb0 781 SUPERFAMILY SSF103025 402 683 4.4E-75 T 13-09-2016 THL1_RS07480 cdf2ff100f184d81f3c702d1bc2ceeb0 781 PANTHER PTHR31527 177 427 3.9E-28 T 13-09-2016 THL1_RS07480 cdf2ff100f184d81f3c702d1bc2ceeb0 781 Pfam PF01571 Aminomethyltransferase folate-binding domain 411 665 2.1E-69 T 13-09-2016 IPR006222 Glycine cleavage T-protein-like, N-terminal THL1_RS07480 cdf2ff100f184d81f3c702d1bc2ceeb0 781 PANTHER PTHR31527:SF0 177 427 3.9E-28 T 13-09-2016 THL1_RS07480 cdf2ff100f184d81f3c702d1bc2ceeb0 781 Gene3D G3DSA:2.40.30.110 691 766 4.8E-19 T 13-09-2016 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THL1_RS01090 00885da30f48a378346860402622b5fc 252 SUPERFAMILY SSF53850 1 251 7.03E-72 T 13-09-2016 THL1_RS01090 00885da30f48a378346860402622b5fc 252 PANTHER PTHR18966:SF152 16 248 1.2E-65 T 13-09-2016 THL1_RS01090 00885da30f48a378346860402622b5fc 252 SMART SM00062 25 250 1.2E-64 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS01090 00885da30f48a378346860402622b5fc 252 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 48 61 - T 13-09-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 THL1_RS01090 00885da30f48a378346860402622b5fc 252 Gene3D G3DSA:3.40.190.10 114 205 4.6E-22 T 13-09-2016 THL1_RS01090 00885da30f48a378346860402622b5fc 252 PANTHER PTHR18966 16 248 1.2E-65 T 13-09-2016 THL1_RS01090 00885da30f48a378346860402622b5fc 252 Gene3D G3DSA:3.40.190.10 22 111 1.6E-48 T 13-09-2016 THL1_RS01090 00885da30f48a378346860402622b5fc 252 Gene3D G3DSA:3.40.190.10 209 251 1.6E-48 T 13-09-2016 THL1_RS01090 00885da30f48a378346860402622b5fc 252 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 26 247 3.2E-65 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS24800 13c22c5e58029958f13c991ffc03d4c6 211 Pfam PF13624 SurA N-terminal domain 21 140 1.5E-19 T 13-09-2016 THL1_RS24800 13c22c5e58029958f13c991ffc03d4c6 211 PANTHER PTHR10657 6 165 3.6E-15 T 13-09-2016 THL1_RS24800 13c22c5e58029958f13c991ffc03d4c6 211 SUPERFAMILY SSF109998 24 167 1.04E-28 T 13-09-2016 IPR027304 Trigger factor/SurA domain THL1_RS11820 6f23cb9079d5561629629df0e334b5d4 301 PANTHER PTHR31367:SF5 1 300 2.6E-138 T 13-09-2016 THL1_RS11820 6f23cb9079d5561629629df0e334b5d4 301 Pfam PF06189 5'-nucleotidase 38 297 4.7E-112 T 13-09-2016 IPR010394 5-nucleotidase GO:0000166|GO:0000287|GO:0005737|GO:0008253|GO:0009117 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|Reactome: REACT_1698 THL1_RS11820 6f23cb9079d5561629629df0e334b5d4 301 PANTHER PTHR31367 1 300 2.6E-138 T 13-09-2016 THL1_RS11910 bdb370f4e142c95f93773c78991fd797 409 Pfam PF11902 Protein of unknown function (DUF3422) 2 405 1.3E-124 T 13-09-2016 IPR021830 Protein of unknown function DUF3422 THL1_RS27980 504641bc88445633020e195ece660364 296 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 73 95 - T 13-09-2016 IPR030470 UbiA prenyltransferase conserved site THL1_RS27980 504641bc88445633020e195ece660364 296 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 11 294 30.615 T 13-09-2016 IPR031103 4-hydroxybenzoate octaprenyltransferase GO:0004659|GO:0006744|GO:0016021 UniPathway: UPA00232 THL1_RS27980 504641bc88445633020e195ece660364 296 Pfam PF01040 UbiA prenyltransferase family 34 278 2.1E-68 T 13-09-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 THL1_RS27980 504641bc88445633020e195ece660364 296 PANTHER PTHR11048 5 296 1.3E-93 T 13-09-2016 THL1_RS27980 504641bc88445633020e195ece660364 296 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 19 293 4.0E-107 T 13-09-2016 IPR006370 4-hydroxybenzoate polyprenyltransferase GO:0004659|GO:0016021 UniPathway: UPA00232 THL1_RS15285 2b24d1d973988b92017ff2ab57f0dd48 97 SUPERFAMILY SSF46689 4 94 1.65E-19 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15285 2b24d1d973988b92017ff2ab57f0dd48 97 Gene3D G3DSA:1.10.10.60 10 90 5.7E-22 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS15285 2b24d1d973988b92017ff2ab57f0dd48 97 PANTHER PTHR33215 1 93 4.3E-24 T 13-09-2016 THL1_RS15285 2b24d1d973988b92017ff2ab57f0dd48 97 Pfam PF01527 Transposase 3 76 1.2E-15 T 13-09-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 THL1_RS11795 5f4e68da3a0d124526566f9754be0bce 94 PANTHER PTHR31435:SF3 2 87 8.3E-38 T 13-09-2016 THL1_RS11795 5f4e68da3a0d124526566f9754be0bce 94 PANTHER PTHR31435 2 87 8.3E-38 T 13-09-2016 THL1_RS11795 5f4e68da3a0d124526566f9754be0bce 94 Gene3D G3DSA:3.40.630.30 2 89 5.5E-32 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS11795 5f4e68da3a0d124526566f9754be0bce 94 Pfam PF14542 GCN5-related N-acetyl-transferase 15 87 3.7E-23 T 13-09-2016 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase THL1_RS11795 5f4e68da3a0d124526566f9754be0bce 94 SUPERFAMILY SSF55729 6 89 2.66E-23 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS16230 208621b0a1c7171869bc36beaa825783 51 Pfam PF15723 Motility quorum-sensing regulator, toxin of MqsA 5 50 2.5E-7 T 13-09-2016 IPR031451 mRNA interferase MqsR GO:0009372|GO:0017148|GO:0042710 THL1_RS07545 2e3a09938438cf0375295742f1648e3c 465 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 17 438 3.6E-40 T 13-09-2016 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 THL1_RS07545 2e3a09938438cf0375295742f1648e3c 465 PIRSF PIRSF002744 1 460 8.2E-96 T 13-09-2016 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 THL1_RS07545 2e3a09938438cf0375295742f1648e3c 465 PANTHER PTHR31806 10 461 6.3E-85 T 13-09-2016 THL1_RS04215 9e4485d56907b49428faba49b0b6f9c8 214 Gene3D G3DSA:3.40.50.620 3 212 1.4E-66 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS04215 9e4485d56907b49428faba49b0b6f9c8 214 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 3 211 30.907 T 13-09-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 THL1_RS04215 9e4485d56907b49428faba49b0b6f9c8 214 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 65 1.7E-10 T 13-09-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THL1_RS04215 9e4485d56907b49428faba49b0b6f9c8 214 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 7 210 3.6E-50 T 13-09-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 THL1_RS04215 9e4485d56907b49428faba49b0b6f9c8 214 Pfam PF01467 Cytidylyltransferase-like 7 184 1.6E-29 T 13-09-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THL1_RS04215 9e4485d56907b49428faba49b0b6f9c8 214 SUPERFAMILY SSF52374 3 212 9.7E-53 T 13-09-2016 THL1_RS04215 9e4485d56907b49428faba49b0b6f9c8 214 PANTHER PTHR12039 1 211 1.7E-52 T 13-09-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 THL1_RS04205 e1d7d7a3607fc3374e1c6cb42d042fb2 409 Pfam PF12697 Alpha/beta hydrolase family 42 275 7.0E-13 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS04205 e1d7d7a3607fc3374e1c6cb42d042fb2 409 Gene3D G3DSA:3.40.50.1820 16 283 2.2E-31 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS04205 e1d7d7a3607fc3374e1c6cb42d042fb2 409 PANTHER PTHR10992:SF107 29 284 1.4E-22 T 13-09-2016 THL1_RS04205 e1d7d7a3607fc3374e1c6cb42d042fb2 409 SUPERFAMILY SSF53474 17 283 3.45E-34 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS04205 e1d7d7a3607fc3374e1c6cb42d042fb2 409 PANTHER PTHR10992 29 284 1.4E-22 T 13-09-2016 THL1_RS04245 b7ed897628d87e3efd18bb3a2a5432cd 336 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 96 187 8.1E-43 T 13-09-2016 IPR012997 Rare lipoprotein A THL1_RS04245 b7ed897628d87e3efd18bb3a2a5432cd 336 Pfam PF03330 Lytic transglycolase 94 183 3.4E-25 T 13-09-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain THL1_RS04245 b7ed897628d87e3efd18bb3a2a5432cd 336 SUPERFAMILY SSF110997 260 331 3.01E-12 T 13-09-2016 IPR007730 Sporulation-related domain GO:0042834 THL1_RS04245 b7ed897628d87e3efd18bb3a2a5432cd 336 Pfam PF05036 Sporulation related domain 258 331 1.3E-13 T 13-09-2016 IPR007730 Sporulation-related domain GO:0042834 THL1_RS04245 b7ed897628d87e3efd18bb3a2a5432cd 336 PANTHER PTHR34183 13 336 4.9E-137 T 13-09-2016 THL1_RS04245 b7ed897628d87e3efd18bb3a2a5432cd 336 Gene3D G3DSA:3.30.70.1070 258 327 4.8E-11 T 13-09-2016 IPR007730 Sporulation-related domain GO:0042834 THL1_RS04245 b7ed897628d87e3efd18bb3a2a5432cd 336 PANTHER PTHR34183:SF1 13 336 4.9E-137 T 13-09-2016 THL1_RS04245 b7ed897628d87e3efd18bb3a2a5432cd 336 SUPERFAMILY SSF50685 95 183 1.05E-10 T 13-09-2016 IPR009009 RlpA-like protein, double-psi beta-barrel domain THL1_RS04385 21170202eaf4a007a25395818df63008 67 Pfam PF10981 Protein of unknown function (DUF2788) 14 60 9.5E-22 T 13-09-2016 IPR021249 Protein of unknown function DUF2788 THL1_RS01385 f90f2377361b4a8f7c80924e1317948d 463 Gene3D G3DSA:3.30.465.10 96 217 4.4E-38 T 13-09-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 THL1_RS01385 f90f2377361b4a8f7c80924e1317948d 463 PANTHER PTHR11748 1 462 1.3E-234 T 13-09-2016 THL1_RS01385 f90f2377361b4a8f7c80924e1317948d 463 SUPERFAMILY SSF55103 222 462 3.43E-60 T 13-09-2016 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 THL1_RS01385 f90f2377361b4a8f7c80924e1317948d 463 PANTHER PTHR11748:SF76 1 462 1.3E-234 T 13-09-2016 THL1_RS01385 f90f2377361b4a8f7c80924e1317948d 463 Gene3D G3DSA:1.10.45.10 422 461 4.2E-14 T 13-09-2016 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 THL1_RS01385 f90f2377361b4a8f7c80924e1317948d 463 Gene3D G3DSA:3.30.43.10 4 95 4.2E-30 T 13-09-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 THL1_RS01385 f90f2377361b4a8f7c80924e1317948d 463 Pfam PF01565 FAD binding domain 41 179 1.0E-37 T 13-09-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THL1_RS01385 f90f2377361b4a8f7c80924e1317948d 463 SUPERFAMILY SSF56176 5 217 8.88E-67 T 13-09-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 THL1_RS01385 f90f2377361b4a8f7c80924e1317948d 463 Pfam PF02913 FAD linked oxidases, C-terminal domain 217 461 4.1E-63 T 13-09-2016 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 THL1_RS04445 c98dca0a68ae3da63e831eef7fcbf273 446 PANTHER PTHR11119 6 430 1.0E-94 T 13-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS04445 c98dca0a68ae3da63e831eef7fcbf273 446 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 13 426 6.9E-96 T 13-09-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 THL1_RS04445 c98dca0a68ae3da63e831eef7fcbf273 446 Pfam PF00860 Permease family 15 394 1.8E-89 T 13-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS04445 c98dca0a68ae3da63e831eef7fcbf273 446 TIGRFAM TIGR03173 pbuX: xanthine permease 20 429 7.2E-137 T 13-09-2016 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 THL1_RS04445 c98dca0a68ae3da63e831eef7fcbf273 446 PANTHER PTHR11119:SF3 6 430 1.0E-94 T 13-09-2016 THL1_RS00755 ba1e5f31b97a4f10b31c8c6322f778de 193 SUPERFAMILY SSF53474 9 178 3.85E-35 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS00755 ba1e5f31b97a4f10b31c8c6322f778de 193 Pfam PF06821 Serine hydrolase 8 179 1.1E-65 T 13-09-2016 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 KEGG: 00231+3.-.-.-|KEGG: 00563+3.-.-.-|KEGG: 00983+3.-.-.- THL1_RS00755 ba1e5f31b97a4f10b31c8c6322f778de 193 Gene3D G3DSA:3.40.50.1820 7 181 4.6E-50 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS07330 74c14fa03e64a3bbd605ee0025a8abb0 100 Pfam PF04267 Sarcosine oxidase, delta subunit family 3 79 2.8E-28 T 13-09-2016 IPR006279 Sarcosine oxidase, delta subunit, heterotetrameric GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 THL1_RS24895 fe40f65cc3dcdd524801f88e8846432b 156 SUPERFAMILY SSF117070 9 151 1.16E-28 T 13-09-2016 THL1_RS24895 fe40f65cc3dcdd524801f88e8846432b 156 SMART SM00769 30 150 8.4E-37 T 13-09-2016 IPR013990 Water stress and hypersensitive response domain GO:0009269 THL1_RS24895 fe40f65cc3dcdd524801f88e8846432b 156 Gene3D G3DSA:2.60.40.10 44 103 4.7E-8 T 13-09-2016 IPR013783 Immunoglobulin-like fold THL1_RS24895 fe40f65cc3dcdd524801f88e8846432b 156 Pfam PF03168 Late embryogenesis abundant protein 50 141 1.4E-20 T 13-09-2016 IPR004864 Late embryogenesis abundant protein, LEA-14 THL1_RS19210 ac6c5a4ecbf742d1fb68dcae2ec6217d 441 PANTHER PTHR11271 1 440 7.8E-181 T 13-09-2016 THL1_RS19210 ac6c5a4ecbf742d1fb68dcae2ec6217d 441 Gene3D G3DSA:3.20.20.140 69 372 1.3E-93 T 13-09-2016 THL1_RS19210 ac6c5a4ecbf742d1fb68dcae2ec6217d 441 Pfam PF01979 Amidohydrolase family 64 412 2.1E-64 T 13-09-2016 IPR006680 Amidohydrolase-related GO:0016787 THL1_RS19210 ac6c5a4ecbf742d1fb68dcae2ec6217d 441 PANTHER PTHR11271:SF7 1 440 7.8E-181 T 13-09-2016 THL1_RS19210 ac6c5a4ecbf742d1fb68dcae2ec6217d 441 SUPERFAMILY SSF51556 66 365 1.5E-90 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS19210 ac6c5a4ecbf742d1fb68dcae2ec6217d 441 SUPERFAMILY SSF51338 9 66 8.46E-24 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS19210 ac6c5a4ecbf742d1fb68dcae2ec6217d 441 SUPERFAMILY SSF51338 364 435 8.46E-24 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS19210 ac6c5a4ecbf742d1fb68dcae2ec6217d 441 Gene3D G3DSA:2.30.40.10 24 68 1.0E-8 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS19210 ac6c5a4ecbf742d1fb68dcae2ec6217d 441 Gene3D G3DSA:2.30.40.10 373 413 1.0E-8 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 PANTHER PTHR11573 18 465 5.9E-207 T 13-09-2016 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 24 659 2.1E-177 T 13-09-2016 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 PANTHER PTHR11573 487 659 5.9E-207 T 13-09-2016 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 PRINTS PR01183 Ribonucleotide reductase large chain signature 355 378 1.2E-18 T 13-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 PRINTS PR01183 Ribonucleotide reductase large chain signature 509 536 1.2E-18 T 13-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 PRINTS PR01183 Ribonucleotide reductase large chain signature 393 415 1.2E-18 T 13-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 PRINTS PR01183 Ribonucleotide reductase large chain signature 421 444 1.2E-18 T 13-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 PRINTS PR01183 Ribonucleotide reductase large chain signature 178 197 1.2E-18 T 13-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 PRINTS PR01183 Ribonucleotide reductase large chain signature 317 328 1.2E-18 T 13-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 Gene3D G3DSA:3.20.70.20 610 652 5.4E-116 T 13-09-2016 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 Gene3D G3DSA:3.20.70.20 283 441 5.4E-116 T 13-09-2016 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 Gene3D G3DSA:3.20.70.20 11 220 5.4E-116 T 13-09-2016 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 Gene3D G3DSA:3.20.70.20 509 557 5.4E-116 T 13-09-2016 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 SUPERFAMILY SSF51998 509 689 4.27E-171 T 13-09-2016 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 SUPERFAMILY SSF51998 10 220 4.27E-171 T 13-09-2016 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 SUPERFAMILY SSF51998 283 441 4.27E-171 T 13-09-2016 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 Pfam PF02867 Ribonucleotide reductase, barrel domain 103 651 1.1E-140 T 13-09-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 PANTHER PTHR11573:SF3 18 465 5.9E-207 T 13-09-2016 THL1_RS00345 a7c3205a65a7ca220d1762bdba3c743f 715 PANTHER PTHR11573:SF3 487 659 5.9E-207 T 13-09-2016 THL1_RS13460 02453cd2335a53ab99e0d561c2c87f31 441 Pfam PF00860 Permease family 14 393 1.8E-97 T 13-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS13460 02453cd2335a53ab99e0d561c2c87f31 441 PANTHER PTHR11119 7 429 1.7E-107 T 13-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS13460 02453cd2335a53ab99e0d561c2c87f31 441 TIGRFAM TIGR03173 pbuX: xanthine permease 19 426 8.5E-150 T 13-09-2016 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 THL1_RS13460 02453cd2335a53ab99e0d561c2c87f31 441 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 12 424 2.3E-108 T 13-09-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 THL1_RS00955 ed835730f8540a54d09d5307732016b6 352 Pfam PF13416 Bacterial extracellular solute-binding protein 36 309 1.8E-28 T 13-09-2016 THL1_RS00955 ed835730f8540a54d09d5307732016b6 352 PANTHER PTHR30222:SF5 4 352 1.6E-94 T 13-09-2016 THL1_RS00955 ed835730f8540a54d09d5307732016b6 352 SUPERFAMILY SSF53850 20 349 3.52E-81 T 13-09-2016 THL1_RS00955 ed835730f8540a54d09d5307732016b6 352 PANTHER PTHR30222 4 352 1.6E-94 T 13-09-2016 THL1_RS00955 ed835730f8540a54d09d5307732016b6 352 PIRSF PIRSF019574 5 352 1.3E-99 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00955 ed835730f8540a54d09d5307732016b6 352 Gene3D G3DSA:3.40.190.10 201 273 1.9E-9 T 13-09-2016 THL1_RS00955 ed835730f8540a54d09d5307732016b6 352 Gene3D G3DSA:3.40.190.10 274 316 2.3E-51 T 13-09-2016 THL1_RS00955 ed835730f8540a54d09d5307732016b6 352 Gene3D G3DSA:3.40.190.10 19 126 2.3E-51 T 13-09-2016 THL1_RS00955 ed835730f8540a54d09d5307732016b6 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 207 226 4.0E-39 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00955 ed835730f8540a54d09d5307732016b6 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 42 63 4.0E-39 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00955 ed835730f8540a54d09d5307732016b6 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 296 322 4.0E-39 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00955 ed835730f8540a54d09d5307732016b6 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 117 133 4.0E-39 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00955 ed835730f8540a54d09d5307732016b6 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 170 189 4.0E-39 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00955 ed835730f8540a54d09d5307732016b6 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 26 42 4.0E-39 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00955 ed835730f8540a54d09d5307732016b6 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 84 97 4.0E-39 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS00955 ed835730f8540a54d09d5307732016b6 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 251 270 4.0E-39 T 13-09-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 THL1_RS06525 ab2adb9ec365120023f6ef28dd7755ac 530 Pfam PF06980 Protein of unknown function (DUF1302) 42 530 2.4E-126 T 13-09-2016 IPR010727 Protein of unknown function DUF1302 THL1_RS00425 3b4822c33779d0166fe25f0fff3d8451 53 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 53 21.875 T 13-09-2016 IPR009760 Protein of unknown function DUF1328 GO:0005886 THL1_RS00425 3b4822c33779d0166fe25f0fff3d8451 53 PIRSF PIRSF036466 1 53 2.8E-24 T 13-09-2016 IPR009760 Protein of unknown function DUF1328 GO:0005886 THL1_RS00425 3b4822c33779d0166fe25f0fff3d8451 53 Pfam PF07043 Protein of unknown function (DUF1328) 6 44 4.8E-18 T 13-09-2016 IPR009760 Protein of unknown function DUF1328 GO:0005886 THL1_RS18450 1131ee2be5120b22dcf4268d97f27194 118 Pfam PF14346 Domain of unknown function (DUF4398) 13 111 8.1E-25 T 13-09-2016 IPR025511 Domain of unknown function DUF4398 THL1_RS06340 3d1f963d10721156f8b2cab518618c25 82 Gene3D G3DSA:3.10.20.30 1 82 3.8E-21 T 13-09-2016 IPR012675 Beta-grasp domain THL1_RS06340 3d1f963d10721156f8b2cab518618c25 82 SUPERFAMILY SSF54285 1 82 8.41E-20 T 13-09-2016 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp THL1_RS06340 3d1f963d10721156f8b2cab518618c25 82 PANTHER PTHR33359 1 82 5.5E-23 T 13-09-2016 THL1_RS06340 3d1f963d10721156f8b2cab518618c25 82 Pfam PF02597 ThiS family 4 82 8.5E-19 T 13-09-2016 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 THL1_RS13725 5d165ebc3f94dd6bd825a0df579c1846 219 TIGRFAM TIGR02305 HpaG-N-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit 11 216 7.1E-92 T 13-09-2016 IPR012686 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit GO:0008704|GO:0018800 KEGG: 00350+5.3.3.10+4.1.1.68|UniPathway: UPA00208|UniPathway: UPA00208 THL1_RS13725 5d165ebc3f94dd6bd825a0df579c1846 219 PANTHER PTHR11820 11 219 2.4E-93 T 13-09-2016 THL1_RS13725 5d165ebc3f94dd6bd825a0df579c1846 219 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 14 217 6.1E-53 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS13725 5d165ebc3f94dd6bd825a0df579c1846 219 PANTHER PTHR11820:SF8 11 219 2.4E-93 T 13-09-2016 THL1_RS13725 5d165ebc3f94dd6bd825a0df579c1846 219 Gene3D G3DSA:3.90.850.10 12 218 3.6E-61 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS13725 5d165ebc3f94dd6bd825a0df579c1846 219 SUPERFAMILY SSF56529 11 217 3.92E-61 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS01850 22f019b51a5ea787b6eb3bb0fd268f09 159 Pfam PF13279 Thioesterase-like superfamily 13 125 2.9E-15 T 13-09-2016 THL1_RS01850 22f019b51a5ea787b6eb3bb0fd268f09 159 Gene3D G3DSA:3.10.129.10 3 140 2.2E-48 T 13-09-2016 IPR029069 HotDog domain THL1_RS01850 22f019b51a5ea787b6eb3bb0fd268f09 159 PANTHER PTHR31793:SF2 7 148 3.9E-61 T 13-09-2016 THL1_RS01850 22f019b51a5ea787b6eb3bb0fd268f09 159 SUPERFAMILY SSF54637 6 156 6.74E-41 T 13-09-2016 IPR029069 HotDog domain THL1_RS01850 22f019b51a5ea787b6eb3bb0fd268f09 159 PANTHER PTHR31793 7 148 3.9E-61 T 13-09-2016 THL1_RS19435 ccbc1d62238b357a51c1b1273a288b03 223 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 8 217 2.1E-85 T 13-09-2016 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria THL1_RS19435 ccbc1d62238b357a51c1b1273a288b03 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 134 157 2.7E-69 T 13-09-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19435 ccbc1d62238b357a51c1b1273a288b03 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 55 72 2.7E-69 T 13-09-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19435 ccbc1d62238b357a51c1b1273a288b03 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 78 101 2.7E-69 T 13-09-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19435 ccbc1d62238b357a51c1b1273a288b03 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 103 121 2.7E-69 T 13-09-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19435 ccbc1d62238b357a51c1b1273a288b03 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 29 50 2.7E-69 T 13-09-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19435 ccbc1d62238b357a51c1b1273a288b03 223 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 195 218 2.7E-69 T 13-09-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19435 ccbc1d62238b357a51c1b1273a288b03 223 PANTHER PTHR30070:SF1 2 222 1.9E-63 T 13-09-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS19435 ccbc1d62238b357a51c1b1273a288b03 223 PANTHER PTHR30070 2 222 1.9E-63 T 13-09-2016 THL1_RS19435 ccbc1d62238b357a51c1b1273a288b03 223 PIRSF PIRSF002764 1 222 1.3E-80 T 13-09-2016 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria THL1_RS19435 ccbc1d62238b357a51c1b1273a288b03 223 Pfam PF03379 CcmB protein 6 218 2.5E-83 T 13-09-2016 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THL1_RS00460 52a0521f42daea132758d17e2bb123c8 252 PANTHER PTHR30060 1 240 1.8E-120 T 13-09-2016 THL1_RS00460 52a0521f42daea132758d17e2bb123c8 252 Pfam PF03741 Integral membrane protein TerC family 14 204 2.4E-51 T 13-09-2016 IPR005496 Integral membrane protein TerC GO:0016021 THL1_RS00460 52a0521f42daea132758d17e2bb123c8 252 PANTHER PTHR30060:SF1 1 240 1.8E-120 T 13-09-2016 THL1_RS01290 336b806683c667554281cd89ede8eb94 98 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 11 82 1.1E-26 T 13-09-2016 IPR003746 Protein of unknown function DUF167 THL1_RS01290 336b806683c667554281cd89ede8eb94 98 SUPERFAMILY SSF69786 2 89 5.89E-30 T 13-09-2016 IPR003746 Protein of unknown function DUF167 THL1_RS01290 336b806683c667554281cd89ede8eb94 98 PANTHER PTHR13420 11 89 2.8E-20 T 13-09-2016 THL1_RS01290 336b806683c667554281cd89ede8eb94 98 SMART SM01152 7 83 6.4E-39 T 13-09-2016 IPR003746 Protein of unknown function DUF167 THL1_RS01290 336b806683c667554281cd89ede8eb94 98 Hamap MF_00634 UPF0235 protein YggU [yggU]. 7 95 20.052 T 13-09-2016 IPR003746 Protein of unknown function DUF167 THL1_RS01290 336b806683c667554281cd89ede8eb94 98 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 7 87 7.8E-23 T 13-09-2016 IPR005228 Conserved hypothetical protein CHP00251 THL1_RS01290 336b806683c667554281cd89ede8eb94 98 Gene3D G3DSA:3.30.1200.10 2 88 4.1E-30 T 13-09-2016 IPR003746 Protein of unknown function DUF167 THL1_RS09310 37ffc5a0dcafd17b49168e4572b8e992 319 TIGRFAM TIGR01230 agmatinase: agmatinase 33 311 1.0E-63 T 13-09-2016 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|UniPathway: UPA00534 THL1_RS09310 37ffc5a0dcafd17b49168e4572b8e992 319 SUPERFAMILY SSF52768 5 313 3.06E-100 T 13-09-2016 THL1_RS09310 37ffc5a0dcafd17b49168e4572b8e992 319 PANTHER PTHR11358 1 316 2.2E-205 T 13-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 THL1_RS09310 37ffc5a0dcafd17b49168e4572b8e992 319 PRINTS PR00116 Arginase signature 125 140 3.3E-13 T 13-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 THL1_RS09310 37ffc5a0dcafd17b49168e4572b8e992 319 PRINTS PR00116 Arginase signature 238 267 3.3E-13 T 13-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 THL1_RS09310 37ffc5a0dcafd17b49168e4572b8e992 319 ProSitePatterns PS01053 Arginase family signature. 241 262 - T 13-09-2016 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 Reactome: REACT_13 THL1_RS09310 37ffc5a0dcafd17b49168e4572b8e992 319 PANTHER PTHR11358:SF27 1 316 2.2E-205 T 13-09-2016 THL1_RS09310 37ffc5a0dcafd17b49168e4572b8e992 319 Pfam PF00491 Arginase family 39 310 5.2E-89 T 13-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 THL1_RS09310 37ffc5a0dcafd17b49168e4572b8e992 319 Gene3D G3DSA:3.40.800.10 8 313 3.2E-126 T 13-09-2016 IPR023696 Ureohydrolase domain THL1_RS09310 37ffc5a0dcafd17b49168e4572b8e992 319 PIRSF PIRSF036979 15 316 1.4E-102 T 13-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 THL1_RS05425 7261e022af5b8eec61ddbceee1fb6449 421 Gene3D G3DSA:3.65.10.10 21 221 1.2E-64 T 13-09-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 THL1_RS05425 7261e022af5b8eec61ddbceee1fb6449 421 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 418 7.7E-178 T 13-09-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS05425 7261e022af5b8eec61ddbceee1fb6449 421 PANTHER PTHR21090 1 421 6.1E-206 T 13-09-2016 THL1_RS05425 7261e022af5b8eec61ddbceee1fb6449 421 SUPERFAMILY SSF55205 1 419 8.18E-141 T 13-09-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 THL1_RS05425 7261e022af5b8eec61ddbceee1fb6449 421 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 419 47.759 T 13-09-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 THL1_RS05425 7261e022af5b8eec61ddbceee1fb6449 421 Gene3D G3DSA:3.65.10.10 222 418 5.4E-59 T 13-09-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 THL1_RS05425 7261e022af5b8eec61ddbceee1fb6449 421 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 409 1.1E-118 T 13-09-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 THL1_RS16420 bb27b831cda1a089a0aaaa73b36ead03 247 Pfam PF01925 Sulfite exporter TauE/SafE 9 240 5.8E-25 T 13-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 THL1_RS09485 963838f16d2fdf057cd266f610c94b49 171 SUPERFAMILY SSF158694 11 171 1.96E-53 T 13-09-2016 THL1_RS09485 963838f16d2fdf057cd266f610c94b49 171 Gene3D G3DSA:1.10.3330.10 11 171 1.0E-60 T 13-09-2016 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|UniPathway: UPA00394 THL1_RS09485 963838f16d2fdf057cd266f610c94b49 171 TIGRFAM TIGR03164 UHCUDC: OHCU decarboxylase 13 171 4.7E-70 T 13-09-2016 IPR017580 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 1 GO:0019428 KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|UniPathway: UPA00394 THL1_RS09485 963838f16d2fdf057cd266f610c94b49 171 Pfam PF09349 OHCU decarboxylase 11 169 1.3E-47 T 13-09-2016 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|UniPathway: UPA00394 THL1_RS05065 688ea23a63dae42699a6efe3b2f643da 203 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 6 188 1.8E-53 T 13-09-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 THL1_RS05065 688ea23a63dae42699a6efe3b2f643da 203 Pfam PF01121 Dephospho-CoA kinase 5 180 4.6E-70 T 13-09-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 THL1_RS05065 688ea23a63dae42699a6efe3b2f643da 203 SUPERFAMILY SSF52540 5 193 1.24E-36 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05065 688ea23a63dae42699a6efe3b2f643da 203 Gene3D G3DSA:3.40.50.300 3 196 3.8E-67 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS05065 688ea23a63dae42699a6efe3b2f643da 203 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 4 198 26.523 T 13-09-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 THL1_RS05065 688ea23a63dae42699a6efe3b2f643da 203 PANTHER PTHR10695 5 196 2.4E-67 T 13-09-2016 THL1_RS25640 9837614cad623c79745557f9c1aae175 224 PANTHER PTHR33620 4 224 2.6E-33 T 13-09-2016 THL1_RS25640 9837614cad623c79745557f9c1aae175 224 Hamap MF_01385 Urease accessory protein UreF [ureF]. 3 224 29.402 T 13-09-2016 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 THL1_RS25640 9837614cad623c79745557f9c1aae175 224 Pfam PF01730 UreF 35 181 8.8E-38 T 13-09-2016 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 THL1_RS25640 9837614cad623c79745557f9c1aae175 224 PIRSF PIRSF009467 1 224 1.5E-59 T 13-09-2016 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 THL1_RS01765 505b4db30b6530a59b38dfd4e235a516 458 PANTHER PTHR30182:SF1 3 454 6.5E-242 T 13-09-2016 THL1_RS01765 505b4db30b6530a59b38dfd4e235a516 458 SUPERFAMILY SSF143548 17 155 1.46E-45 T 13-09-2016 IPR029009 Allosteric substrate binding domain THL1_RS01765 505b4db30b6530a59b38dfd4e235a516 458 PANTHER PTHR30182 3 454 6.5E-242 T 13-09-2016 THL1_RS01765 505b4db30b6530a59b38dfd4e235a516 458 Pfam PF03313 Serine dehydratase alpha chain 186 452 1.1E-103 T 13-09-2016 IPR005130 Serine dehydratase-like, alpha subunit THL1_RS01765 505b4db30b6530a59b38dfd4e235a516 458 Gene3D G3DSA:3.30.1330.90 11 156 1.7E-53 T 13-09-2016 IPR029009 Allosteric substrate binding domain THL1_RS01765 505b4db30b6530a59b38dfd4e235a516 458 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 454 4.7E-212 T 13-09-2016 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 THL1_RS01765 505b4db30b6530a59b38dfd4e235a516 458 Pfam PF03315 Serine dehydratase beta chain 4 155 1.1E-56 T 13-09-2016 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 THL1_RS05745 adfff0133d9a25e114dc590b7d0c3a59 579 Gene3D G3DSA:1.20.1250.20 18 214 2.5E-15 T 13-09-2016 THL1_RS05745 adfff0133d9a25e114dc590b7d0c3a59 579 Gene3D G3DSA:1.20.1250.20 373 562 1.9E-9 T 13-09-2016 THL1_RS05745 adfff0133d9a25e114dc590b7d0c3a59 579 PANTHER PTHR12778 345 551 1.1E-91 T 13-09-2016 THL1_RS05745 adfff0133d9a25e114dc590b7d0c3a59 579 PANTHER PTHR12778 21 215 1.1E-91 T 13-09-2016 THL1_RS05745 adfff0133d9a25e114dc590b7d0c3a59 579 TIGRFAM TIGR00901 2A0125: AmpG-like permease 29 514 3.9E-133 T 13-09-2016 IPR004752 AmpG-like permease/Acetyl-coenzyme A transporter 1 GO:0016020 THL1_RS05745 adfff0133d9a25e114dc590b7d0c3a59 579 Pfam PF07690 Major Facilitator Superfamily 21 382 2.3E-10 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS05745 adfff0133d9a25e114dc590b7d0c3a59 579 SUPERFAMILY SSF103473 367 563 1.96E-29 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS05745 adfff0133d9a25e114dc590b7d0c3a59 579 SUPERFAMILY SSF103473 18 225 1.96E-29 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS18545 68ee647045c4a1f5bdf7f080ec0d2f43 311 Pfam PF00589 Phage integrase family 35 241 6.3E-6 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS18545 68ee647045c4a1f5bdf7f080ec0d2f43 311 SUPERFAMILY SSF56349 34 239 1.21E-11 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS18545 68ee647045c4a1f5bdf7f080ec0d2f43 311 Gene3D G3DSA:1.10.443.10 34 241 1.8E-11 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS06125 07c6c26f665d42d64c54d6654f26a77b 285 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 29 259 5.6E-51 T 13-09-2016 THL1_RS06125 07c6c26f665d42d64c54d6654f26a77b 285 Gene3D G3DSA:3.40.190.10 113 164 7.9E-6 T 13-09-2016 THL1_RS06125 07c6c26f665d42d64c54d6654f26a77b 285 SUPERFAMILY SSF53850 25 252 1.15E-18 T 13-09-2016 THL1_RS27475 2c6c248a581b197984fc5a54cf2b7f5f 944 Pfam PF12633 Adenylate cyclase NT domain 20 216 2.8E-77 T 13-09-2016 IPR024685 Adenylate cyclase class-I, N-terminal domain KEGG: 00230+4.6.1.1 THL1_RS27475 2c6c248a581b197984fc5a54cf2b7f5f 944 PANTHER PTHR38760 17 866 1.4E-285 T 13-09-2016 THL1_RS27475 2c6c248a581b197984fc5a54cf2b7f5f 944 PIRSF PIRSF001444 16 925 9.7E-286 T 13-09-2016 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 THL1_RS27475 2c6c248a581b197984fc5a54cf2b7f5f 944 Pfam PF01295 Adenylate cyclase, class-I 243 802 3.0E-119 T 13-09-2016 IPR000274 Adenylate cyclase, class-I GO:0004016|GO:0006171 KEGG: 00230+4.6.1.1 THL1_RS13215 d179e38c80050719a4fa93091567ecde 204 SUPERFAMILY SSF46689 7 83 1.33E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS13215 d179e38c80050719a4fa93091567ecde 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.9E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS13215 d179e38c80050719a4fa93091567ecde 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.9E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS13215 d179e38c80050719a4fa93091567ecde 204 PANTHER PTHR30055 7 118 1.0E-15 T 13-09-2016 THL1_RS13215 d179e38c80050719a4fa93091567ecde 204 Gene3D G3DSA:1.10.357.10 7 188 3.3E-24 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS13215 d179e38c80050719a4fa93091567ecde 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 55 1.8E-10 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS12550 3419b2b516cbe1727e3693d7f826e51b 268 Pfam PF01738 Dienelactone hydrolase family 38 265 2.5E-45 T 13-09-2016 IPR002925 Dienelactone hydrolase GO:0016787 THL1_RS12550 3419b2b516cbe1727e3693d7f826e51b 268 PANTHER PTHR22946 18 267 1.4E-69 T 13-09-2016 THL1_RS12550 3419b2b516cbe1727e3693d7f826e51b 268 Gene3D G3DSA:3.40.50.1820 25 267 4.3E-48 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS12550 3419b2b516cbe1727e3693d7f826e51b 268 SUPERFAMILY SSF53474 26 267 7.72E-43 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS12550 3419b2b516cbe1727e3693d7f826e51b 268 PANTHER PTHR22946:SF0 18 267 1.4E-69 T 13-09-2016 THL1_RS28100 80b0efbbdd734c5529e52baf3a609e48 206 SUPERFAMILY SSF52833 40 196 3.31E-29 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS28100 80b0efbbdd734c5529e52baf3a609e48 206 PANTHER PTHR12151 45 151 1.4E-24 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS28100 80b0efbbdd734c5529e52baf3a609e48 206 Pfam PF02630 SCO1/SenC 55 144 1.2E-10 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS28100 80b0efbbdd734c5529e52baf3a609e48 206 Gene3D G3DSA:3.40.30.10 15 196 3.0E-29 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS26920 e69580e407b6e3c981f9a4b3987f5c34 326 Pfam PF12835 Integrase 130 274 5.5E-7 T 13-09-2016 IPR024456 Integrase catalytic domain, putative THL1_RS26920 e69580e407b6e3c981f9a4b3987f5c34 326 Gene3D G3DSA:1.10.150.130 35 106 2.9E-7 T 13-09-2016 IPR023109 Integrase/recombinase, N-terminal THL1_RS26920 e69580e407b6e3c981f9a4b3987f5c34 326 Gene3D G3DSA:1.10.443.10 138 322 1.4E-8 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS26920 e69580e407b6e3c981f9a4b3987f5c34 326 SUPERFAMILY SSF56349 60 278 9.12E-12 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS13345 fb6c4de79e2793b47928b64db6e722b1 527 Pfam PF07690 Major Facilitator Superfamily 26 421 4.2E-27 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS13345 fb6c4de79e2793b47928b64db6e722b1 527 SUPERFAMILY SSF103473 485 507 3.14E-27 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS13345 fb6c4de79e2793b47928b64db6e722b1 527 SUPERFAMILY SSF103473 23 209 3.14E-27 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS13345 fb6c4de79e2793b47928b64db6e722b1 527 SUPERFAMILY SSF103473 259 431 3.14E-27 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS13345 fb6c4de79e2793b47928b64db6e722b1 527 PANTHER PTHR23501 19 515 1.1E-45 T 13-09-2016 THL1_RS13345 fb6c4de79e2793b47928b64db6e722b1 527 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 19 507 1.3E-69 T 13-09-2016 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 THL1_RS13345 fb6c4de79e2793b47928b64db6e722b1 527 Gene3D G3DSA:1.20.1250.20 272 435 2.9E-4 T 13-09-2016 THL1_RS13345 fb6c4de79e2793b47928b64db6e722b1 527 Gene3D G3DSA:1.20.1250.20 21 205 4.2E-14 T 13-09-2016 THL1_RS28270 501a9c18ba711583fe50ebeba0fd449d 154 Pfam PF04073 Aminoacyl-tRNA editing domain 23 143 6.8E-22 T 13-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THL1_RS28270 501a9c18ba711583fe50ebeba0fd449d 154 Gene3D G3DSA:3.90.960.10 5 153 1.6E-21 T 13-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THL1_RS28270 501a9c18ba711583fe50ebeba0fd449d 154 SUPERFAMILY SSF55826 6 150 5.1E-28 T 13-09-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THL1_RS13300 29159817647f03cb8d530a5c96d131f3 170 ProSitePatterns PS00018 EF-hand calcium-binding domain. 130 142 - T 13-09-2016 IPR018247 EF-Hand 1, calcium-binding site THL1_RS13300 29159817647f03cb8d530a5c96d131f3 170 Pfam PF13202 EF hand 99 118 0.036 T 13-09-2016 IPR002048 EF-hand domain GO:0005509 THL1_RS13300 29159817647f03cb8d530a5c96d131f3 170 Pfam PF13202 EF hand 126 144 0.0091 T 13-09-2016 IPR002048 EF-hand domain GO:0005509 THL1_RS13300 29159817647f03cb8d530a5c96d131f3 170 ProSitePatterns PS00018 EF-hand calcium-binding domain. 103 115 - T 13-09-2016 IPR018247 EF-Hand 1, calcium-binding site THL1_RS13300 29159817647f03cb8d530a5c96d131f3 170 SUPERFAMILY SSF47473 99 160 1.54E-6 T 13-09-2016 IPR011992 EF-hand domain pair THL1_RS13300 29159817647f03cb8d530a5c96d131f3 170 Gene3D G3DSA:1.10.238.10 97 162 4.2E-6 T 13-09-2016 IPR011992 EF-hand domain pair THL1_RS12125 928ca25abdbe0fe333932b7cf5edb437 85 Pfam PF10976 Protein of unknown function (DUF2790) 11 82 4.1E-27 T 13-09-2016 IPR021245 Protein of unknown function DUF2790 THL1_RS25135 05b77adb07d3c3453cf7c3b8e2d91ae6 213 Gene3D G3DSA:3.40.50.720 1 213 5.6E-46 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS25135 05b77adb07d3c3453cf7c3b8e2d91ae6 213 PANTHER PTHR15020 1 213 1.4E-75 T 13-09-2016 THL1_RS25135 05b77adb07d3c3453cf7c3b8e2d91ae6 213 PANTHER PTHR15020:SF29 1 213 1.4E-75 T 13-09-2016 THL1_RS25135 05b77adb07d3c3453cf7c3b8e2d91ae6 213 SUPERFAMILY SSF51735 1 212 4.37E-43 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS25135 05b77adb07d3c3453cf7c3b8e2d91ae6 213 Pfam PF13460 NAD(P)H-binding 7 198 4.8E-39 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS27275 e29e2293eb6e720a617fa848cdaa5168 201 PANTHER PTHR23407 1 199 6.2E-52 T 13-09-2016 THL1_RS27275 e29e2293eb6e720a617fa848cdaa5168 201 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 9 193 6.7E-40 T 13-09-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase THL1_RS27275 e29e2293eb6e720a617fa848cdaa5168 201 Gene3D G3DSA:3.40.50.10420 9 198 4.5E-53 T 13-09-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain THL1_RS27275 e29e2293eb6e720a617fa848cdaa5168 201 SUPERFAMILY SSF100950 8 198 1.81E-50 T 13-09-2016 THL1_RS27275 e29e2293eb6e720a617fa848cdaa5168 201 PIRSF PIRSF006806 5 196 4.0E-33 T 13-09-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase THL1_RS27275 e29e2293eb6e720a617fa848cdaa5168 201 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 9 193 9.2E-45 T 13-09-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase THL1_RS27275 e29e2293eb6e720a617fa848cdaa5168 201 PANTHER PTHR23407:SF1 1 199 6.2E-52 T 13-09-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase THL1_RS24495 7fa664b39c8b5a0d4cd37fedec08e611 189 SUPERFAMILY SSF58014 25 119 3.27E-27 T 13-09-2016 THL1_RS24495 7fa664b39c8b5a0d4cd37fedec08e611 189 Gene3D G3DSA:2.30.22.10 121 178 1.4E-25 T 13-09-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 THL1_RS24495 7fa664b39c8b5a0d4cd37fedec08e611 189 PRINTS PR00773 GrpE protein signature 45 61 3.0E-26 T 13-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 THL1_RS24495 7fa664b39c8b5a0d4cd37fedec08e611 189 PRINTS PR00773 GrpE protein signature 128 143 3.0E-26 T 13-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 THL1_RS24495 7fa664b39c8b5a0d4cd37fedec08e611 189 PRINTS PR00773 GrpE protein signature 155 174 3.0E-26 T 13-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 THL1_RS24495 7fa664b39c8b5a0d4cd37fedec08e611 189 PRINTS PR00773 GrpE protein signature 73 88 3.0E-26 T 13-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 THL1_RS24495 7fa664b39c8b5a0d4cd37fedec08e611 189 SUPERFAMILY SSF51064 121 177 1.7E-18 T 13-09-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 THL1_RS24495 7fa664b39c8b5a0d4cd37fedec08e611 189 Pfam PF01025 GrpE 15 176 1.2E-51 T 13-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 THL1_RS24495 7fa664b39c8b5a0d4cd37fedec08e611 189 Gene3D G3DSA:3.90.20.20 24 119 1.5E-30 T 13-09-2016 IPR013805 GrpE nucleotide exchange factor, coiled-coil THL1_RS24495 7fa664b39c8b5a0d4cd37fedec08e611 189 PANTHER PTHR21237 8 179 7.0E-61 T 13-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 THL1_RS24495 7fa664b39c8b5a0d4cd37fedec08e611 189 Hamap MF_01151 Protein GrpE [grpE]. 2 176 20.611 T 13-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 THL1_RS24495 7fa664b39c8b5a0d4cd37fedec08e611 189 ProSitePatterns PS01071 grpE protein signature. 131 174 - T 13-09-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 THL1_RS04740 26b88ca554102cda564ae130db479885 67 Pfam PF04328 Protein of unknown function (DUF466) 5 67 2.6E-30 T 13-09-2016 IPR007423 Protein of unknown function DUF466 THL1_RS04740 26b88ca554102cda564ae130db479885 67 PANTHER PTHR38453:SF1 1 67 7.2E-42 T 13-09-2016 THL1_RS04740 26b88ca554102cda564ae130db479885 67 PANTHER PTHR38453 1 67 7.2E-42 T 13-09-2016 THL1_RS06300 e0f69f9d9365047783c551761c3451f6 453 SUPERFAMILY SSF81901 249 414 2.44E-21 T 13-09-2016 THL1_RS06300 e0f69f9d9365047783c551761c3451f6 453 SUPERFAMILY SSF81901 28 194 1.57E-6 T 13-09-2016 THL1_RS06300 e0f69f9d9365047783c551761c3451f6 453 SMART SM00671 337 372 0.1 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS06300 e0f69f9d9365047783c551761c3451f6 453 SMART SM00671 373 408 2.2 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS06300 e0f69f9d9365047783c551761c3451f6 453 SMART SM00671 302 334 0.27 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS06300 e0f69f9d9365047783c551761c3451f6 453 SMART SM00671 54 88 150.0 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS06300 e0f69f9d9365047783c551761c3451f6 453 Gene3D G3DSA:1.25.40.10 28 119 6.2E-33 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS06300 e0f69f9d9365047783c551761c3451f6 453 Gene3D G3DSA:1.25.40.10 259 425 6.2E-33 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS06300 e0f69f9d9365047783c551761c3451f6 453 Pfam PF08238 Sel1 repeat 303 333 6.8E-4 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS06300 e0f69f9d9365047783c551761c3451f6 453 Pfam PF08238 Sel1 repeat 377 397 7.8 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS06300 e0f69f9d9365047783c551761c3451f6 453 Pfam PF08238 Sel1 repeat 338 371 0.017 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS06300 e0f69f9d9365047783c551761c3451f6 453 PANTHER PTHR11102 269 417 2.9E-16 T 13-09-2016 THL1_RS06300 e0f69f9d9365047783c551761c3451f6 453 PANTHER PTHR11102 35 126 2.9E-16 T 13-09-2016 THL1_RS18155 6f7679a89a4c445778a02e8f1718c190 328 Pfam PF00561 alpha/beta hydrolase fold 57 151 1.3E-12 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS18155 6f7679a89a4c445778a02e8f1718c190 328 Gene3D G3DSA:3.40.50.1820 231 312 4.3E-7 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS18155 6f7679a89a4c445778a02e8f1718c190 328 Gene3D G3DSA:3.40.50.1820 39 155 1.0E-28 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS18155 6f7679a89a4c445778a02e8f1718c190 328 SUPERFAMILY SSF53474 51 313 1.91E-31 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS18155 6f7679a89a4c445778a02e8f1718c190 328 PANTHER PTHR11005 40 151 1.2E-23 T 13-09-2016 THL1_RS06675 c8e2d31b27f19e7574c7786ba4f5dcc2 104 SUPERFAMILY SSF47413 47 99 1.42E-13 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS06675 c8e2d31b27f19e7574c7786ba4f5dcc2 104 SMART SM00530 47 102 3.0E-13 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS06675 c8e2d31b27f19e7574c7786ba4f5dcc2 104 Pfam PF13560 Helix-turn-helix domain 47 99 7.8E-13 T 13-09-2016 THL1_RS06675 c8e2d31b27f19e7574c7786ba4f5dcc2 104 Gene3D G3DSA:1.10.260.40 47 98 1.5E-14 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS13585 97fcb337186140e5cf69b82b57a15060 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 293 1.8E-13 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS13585 97fcb337186140e5cf69b82b57a15060 308 PANTHER PTHR30193:SF10 14 302 1.7E-112 T 13-09-2016 THL1_RS13585 97fcb337186140e5cf69b82b57a15060 308 SUPERFAMILY SSF161098 21 302 2.34E-48 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS13585 97fcb337186140e5cf69b82b57a15060 308 PANTHER PTHR30193 14 302 1.7E-112 T 13-09-2016 THL1_RS13585 97fcb337186140e5cf69b82b57a15060 308 Gene3D G3DSA:1.10.3720.10 16 293 4.7E-45 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS15885 a614256997e69e043d4b71b7f1c4308a 535 SUPERFAMILY SSF52096 24 269 1.71E-73 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS15885 a614256997e69e043d4b71b7f1c4308a 535 SUPERFAMILY SSF52096 237 517 1.6E-88 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS15885 a614256997e69e043d4b71b7f1c4308a 535 PANTHER PTHR22855:SF35 1 535 0.0 T 13-09-2016 THL1_RS15885 a614256997e69e043d4b71b7f1c4308a 535 Pfam PF01039 Carboxyl transferase domain 48 526 2.9E-155 T 13-09-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 THL1_RS15885 a614256997e69e043d4b71b7f1c4308a 535 Gene3D G3DSA:3.90.226.10 279 530 1.7E-91 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS15885 a614256997e69e043d4b71b7f1c4308a 535 Gene3D G3DSA:3.90.226.10 37 272 1.2E-82 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS15885 a614256997e69e043d4b71b7f1c4308a 535 PANTHER PTHR22855 1 535 0.0 T 13-09-2016 THL1_RS07290 e51324e9f6610d5e2e7ce6d8d4a0f969 129 Gene3D G3DSA:1.20.1290.10 3 126 1.1E-31 T 13-09-2016 IPR029032 AhpD-like THL1_RS07290 e51324e9f6610d5e2e7ce6d8d4a0f969 129 PANTHER PTHR33570:SF2 3 128 5.6E-57 T 13-09-2016 THL1_RS07290 e51324e9f6610d5e2e7ce6d8d4a0f969 129 PANTHER PTHR33570 3 128 5.6E-57 T 13-09-2016 THL1_RS07290 e51324e9f6610d5e2e7ce6d8d4a0f969 129 Pfam PF02627 Carboxymuconolactone decarboxylase family 36 118 1.1E-22 T 13-09-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS07290 e51324e9f6610d5e2e7ce6d8d4a0f969 129 SUPERFAMILY SSF69118 4 122 2.49E-36 T 13-09-2016 IPR029032 AhpD-like THL1_RS00710 c817ffae8eab25cd946181c5f0428f0e 60 Pfam PF10055 Uncharacterized small protein (DUF2292) 17 52 3.4E-18 T 13-09-2016 IPR018743 Protein of unknown function DUF2292 THL1_RS11660 3cd3470c99a7f46ac1ad045cec383813 376 PANTHER PTHR34219:SF3 1 364 3.2E-71 T 13-09-2016 THL1_RS11660 3cd3470c99a7f46ac1ad045cec383813 376 PANTHER PTHR34219 1 364 3.2E-71 T 13-09-2016 THL1_RS11660 3cd3470c99a7f46ac1ad045cec383813 376 Pfam PF03929 PepSY-associated TM region 11 361 1.5E-51 T 13-09-2016 IPR005625 PepSY-associated TM protein THL1_RS28455 dde4db808c471649b231ac441a5c0db7 135 Pfam PF03899 ATP synthase I chain 19 114 3.7E-23 T 13-09-2016 IPR005598 ATP synthase protein I THL1_RS12715 0666fae2026d8f1e35d78c23464830b7 299 Pfam PF01545 Cation efflux family 9 208 3.2E-35 T 13-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THL1_RS12715 0666fae2026d8f1e35d78c23464830b7 299 SUPERFAMILY SSF161111 4 208 4.84E-31 T 13-09-2016 THL1_RS12715 0666fae2026d8f1e35d78c23464830b7 299 PANTHER PTHR11562 1 231 1.4E-14 T 13-09-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THL1_RS12715 0666fae2026d8f1e35d78c23464830b7 299 Gene3D G3DSA:1.20.1510.10 6 207 5.6E-23 T 13-09-2016 IPR027469 Cation efflux protein transmembrane domain THL1_RS26995 b518a31e3386276ce65a96bdc1a7591b 120 Pfam PF16703 Domain of unknown function (DUF5064) 1 115 8.4E-31 T 13-09-2016 IPR032024 Protein of unknown function DUF5064 THL1_RS02100 25987eb827509fb133d7d6a63e95eed3 449 Pfam PF06123 Inner membrane protein CreD 5 438 6.8E-166 T 13-09-2016 IPR010364 Uncharacterised protein family, inner membrane CreD THL1_RS02100 25987eb827509fb133d7d6a63e95eed3 449 PIRSF PIRSF004548 1 447 4.5E-164 T 13-09-2016 IPR010364 Uncharacterised protein family, inner membrane CreD THL1_RS02100 25987eb827509fb133d7d6a63e95eed3 449 PANTHER PTHR30092 1 442 3.6E-171 T 13-09-2016 THL1_RS13400 f12ec5ccf94931d76251e89c8b96173f 393 PANTHER PTHR38674 18 388 9.3E-54 T 13-09-2016 THL1_RS13400 f12ec5ccf94931d76251e89c8b96173f 393 Pfam PF00487 Fatty acid desaturase 121 322 2.5E-26 T 13-09-2016 IPR005804 Fatty acid desaturase domain GO:0006629 THL1_RS13400 f12ec5ccf94931d76251e89c8b96173f 393 PANTHER PTHR38674:SF1 18 388 9.3E-54 T 13-09-2016 THL1_RS03680 65b95192ec0719fa7dd3e495b0ef85ec 804 Gene3D G3DSA:2.40.170.20 277 804 3.5E-166 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS03680 65b95192ec0719fa7dd3e495b0ef85ec 804 PANTHER PTHR32552:SF21 148 804 0.0 T 13-09-2016 THL1_RS03680 65b95192ec0719fa7dd3e495b0ef85ec 804 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 158 804 6.7E-142 T 13-09-2016 IPR010105 TonB-dependent siderophore receptor GO:0004872|GO:0005506|GO:0015891 THL1_RS03680 65b95192ec0719fa7dd3e495b0ef85ec 804 PANTHER PTHR32552 148 804 0.0 T 13-09-2016 THL1_RS03680 65b95192ec0719fa7dd3e495b0ef85ec 804 SUPERFAMILY SSF56935 148 804 1.23E-143 T 13-09-2016 THL1_RS03680 65b95192ec0719fa7dd3e495b0ef85ec 804 Gene3D G3DSA:2.170.130.10 136 269 7.9E-37 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS03680 65b95192ec0719fa7dd3e495b0ef85ec 804 Pfam PF07715 TonB-dependent Receptor Plug Domain 156 261 4.0E-22 T 13-09-2016 IPR012910 TonB-dependent receptor, plug domain GO:0004872|GO:0006810|GO:0016020 THL1_RS03680 65b95192ec0719fa7dd3e495b0ef85ec 804 Pfam PF00593 TonB dependent receptor 568 803 1.5E-34 T 13-09-2016 IPR000531 TonB-dependent receptor, beta-barrel GO:0004872|GO:0006810|GO:0016020 THL1_RS03680 65b95192ec0719fa7dd3e495b0ef85ec 804 SMART SM00965 64 115 8.9E-9 T 13-09-2016 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 THL1_RS18145 4d6c6160320f3e3b7d84c3d44f7ced0b 331 PANTHER PTHR21535 71 331 5.4E-29 T 13-09-2016 THL1_RS18145 4d6c6160320f3e3b7d84c3d44f7ced0b 331 Gene3D G3DSA:1.20.58.340 257 331 3.7E-21 T 13-09-2016 THL1_RS18145 4d6c6160320f3e3b7d84c3d44f7ced0b 331 SUPERFAMILY SSF143865 8 257 5.1E-44 T 13-09-2016 THL1_RS18145 4d6c6160320f3e3b7d84c3d44f7ced0b 331 SUPERFAMILY SSF144083 266 328 2.88E-15 T 13-09-2016 THL1_RS18145 4d6c6160320f3e3b7d84c3d44f7ced0b 331 Pfam PF01544 CorA-like Mg2+ transporter protein 39 327 1.6E-62 T 13-09-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 THL1_RS18145 4d6c6160320f3e3b7d84c3d44f7ced0b 331 Gene3D G3DSA:1.20.58.340 145 252 1.3E-10 T 13-09-2016 THL1_RS18290 8e4307f32b4376e787a97ce00123d198 190 SMART SM00463 97 181 5.0E-7 T 13-09-2016 IPR002625 Smr domain THL1_RS18290 8e4307f32b4376e787a97ce00123d198 190 PANTHER PTHR35562:SF2 1 190 1.9E-74 T 13-09-2016 THL1_RS18290 8e4307f32b4376e787a97ce00123d198 190 Pfam PF01713 Smr domain 100 181 1.4E-21 T 13-09-2016 IPR002625 Smr domain THL1_RS18290 8e4307f32b4376e787a97ce00123d198 190 SUPERFAMILY SSF160443 98 181 6.02E-16 T 13-09-2016 IPR002625 Smr domain THL1_RS18290 8e4307f32b4376e787a97ce00123d198 190 PANTHER PTHR35562 1 190 1.9E-74 T 13-09-2016 THL1_RS04685 74dcb0a8031b93b8522385c45c09fb5d 478 PANTHER PTHR10422 9 463 6.6E-297 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS04685 74dcb0a8031b93b8522385c45c09fb5d 478 Gene3D G3DSA:1.20.210.10 11 466 3.0E-67 T 13-09-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS04685 74dcb0a8031b93b8522385c45c09fb5d 478 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 13 443 2.0E-108 T 13-09-2016 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS04685 74dcb0a8031b93b8522385c45c09fb5d 478 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 9 466 9.5E-222 T 13-09-2016 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS04685 74dcb0a8031b93b8522385c45c09fb5d 478 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 204 259 - T 13-09-2016 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS04685 74dcb0a8031b93b8522385c45c09fb5d 478 SUPERFAMILY SSF81442 10 468 2.09E-119 T 13-09-2016 IPR023616 Cytochrome c oxidase, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|UniPathway: UPA00705 THL1_RS04685 74dcb0a8031b93b8522385c45c09fb5d 478 PANTHER PTHR10422:SF21 9 463 6.6E-297 T 13-09-2016 THL1_RS23220 9026bff7f5a722d7a63e7bdf07691f84 193 Pfam PF04264 YceI-like domain 23 164 6.1E-11 T 13-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THL1_RS23220 9026bff7f5a722d7a63e7bdf07691f84 193 Gene3D G3DSA:2.40.128.110 21 163 1.7E-9 T 13-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THL1_RS23220 9026bff7f5a722d7a63e7bdf07691f84 193 SMART SM00867 22 191 4.8E-14 T 13-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THL1_RS23220 9026bff7f5a722d7a63e7bdf07691f84 193 PIRSF PIRSF029811 2 193 9.1E-66 T 13-09-2016 IPR027016 Uncharacterised protein with YceI domain THL1_RS23220 9026bff7f5a722d7a63e7bdf07691f84 193 SUPERFAMILY SSF101874 21 191 2.49E-19 T 13-09-2016 IPR007372 Lipid/polyisoprenoid-binding, YceI-like THL1_RS13395 1628cbc4c94b23db9b9af5ae6e9b525a 455 Gene3D G3DSA:2.50.20.10 342 450 7.7E-40 T 13-09-2016 THL1_RS13395 1628cbc4c94b23db9b9af5ae6e9b525a 455 Gene3D G3DSA:2.50.20.10 161 309 7.7E-40 T 13-09-2016 THL1_RS13395 1628cbc4c94b23db9b9af5ae6e9b525a 455 Pfam PF07044 Protein of unknown function (DUF1329) 83 450 3.9E-149 T 13-09-2016 IPR010752 Protein of unknown function DUF1329 THL1_RS07250 2438e400199a9616e348ea6eb9ecd256 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 264 9.2E-15 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07250 2438e400199a9616e348ea6eb9ecd256 269 Gene3D G3DSA:1.10.3720.10 17 265 7.5E-52 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07250 2438e400199a9616e348ea6eb9ecd256 269 SUPERFAMILY SSF161098 11 265 4.39E-57 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS07250 2438e400199a9616e348ea6eb9ecd256 269 PANTHER PTHR30193:SF20 7 265 1.5E-71 T 13-09-2016 THL1_RS07250 2438e400199a9616e348ea6eb9ecd256 269 PANTHER PTHR30193 7 265 1.5E-71 T 13-09-2016 THL1_RS17850 6005dcd27cbd46b30aa702c83fe88d5e 453 Pfam PF13520 Amino acid permease 14 412 1.3E-58 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS17850 6005dcd27cbd46b30aa702c83fe88d5e 453 PANTHER PTHR11785 13 446 3.5E-153 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS17850 6005dcd27cbd46b30aa702c83fe88d5e 453 PIRSF PIRSF006060 2 450 2.7E-75 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS17850 6005dcd27cbd46b30aa702c83fe88d5e 453 PANTHER PTHR11785:SF259 13 446 3.5E-153 T 13-09-2016 THL1_RS21030 69a41f2268175bb0635b2b837a1b6572 161 Gene3D G3DSA:3.10.129.10 14 156 3.5E-23 T 13-09-2016 IPR029069 HotDog domain THL1_RS21030 69a41f2268175bb0635b2b837a1b6572 161 SUPERFAMILY SSF54637 17 157 3.2E-20 T 13-09-2016 IPR029069 HotDog domain THL1_RS26765 7494e98c95d9dd93b4d4aad4d0e999ed 132 Gene3D G3DSA:3.40.630.30 12 120 5.7E-13 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS26765 7494e98c95d9dd93b4d4aad4d0e999ed 132 SUPERFAMILY SSF55729 10 124 4.12E-13 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS26765 7494e98c95d9dd93b4d4aad4d0e999ed 132 Pfam PF12568 Acetyltransferase (GNAT) domain 2 100 2.0E-31 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS26755 4bdf48acce73fb0022dfb0283ce55ee4 212 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 208 34.866 T 13-09-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 THL1_RS26755 4bdf48acce73fb0022dfb0283ce55ee4 212 SUPERFAMILY SSF52317 2 208 5.18E-56 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS26755 4bdf48acce73fb0022dfb0283ce55ee4 212 PANTHER PTHR21235:SF1 4 208 5.4E-85 T 13-09-2016 THL1_RS26755 4bdf48acce73fb0022dfb0283ce55ee4 212 Pfam PF00117 Glutamine amidotransferase class-I 6 205 1.4E-18 T 13-09-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 THL1_RS26755 4bdf48acce73fb0022dfb0283ce55ee4 212 PIRSF PIRSF000495 2 210 1.7E-67 T 13-09-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 THL1_RS26755 4bdf48acce73fb0022dfb0283ce55ee4 212 PANTHER PTHR21235 4 208 5.4E-85 T 13-09-2016 THL1_RS26755 4bdf48acce73fb0022dfb0283ce55ee4 212 Gene3D G3DSA:3.40.50.880 1 208 3.2E-78 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS26755 4bdf48acce73fb0022dfb0283ce55ee4 212 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 207 1.5E-65 T 13-09-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 THL1_RS08710 c4865fef8cf8ba7e33489ee0ff49d2c3 304 Gene3D G3DSA:1.10.760.10 136 230 1.1E-5 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS08710 c4865fef8cf8ba7e33489ee0ff49d2c3 304 Pfam PF07635 Planctomycete cytochrome C 153 210 2.0E-4 T 13-09-2016 IPR011429 Cytochrome C, Planctomycete THL1_RS08710 c4865fef8cf8ba7e33489ee0ff49d2c3 304 Pfam PF07635 Planctomycete cytochrome C 38 92 1.2E-7 T 13-09-2016 IPR011429 Cytochrome C, Planctomycete THL1_RS08710 c4865fef8cf8ba7e33489ee0ff49d2c3 304 SUPERFAMILY SSF46626 140 233 4.43E-8 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS01825 d30e2634c222cd660e0d0a1c9b56b396 73 Pfam PF11390 NADH-dependant formate dehydrogenase delta subunit FdsD 5 66 2.1E-26 T 13-09-2016 IPR021074 Formate dehydrogenase, delta subunit THL1_RS21560 8eec7f08161e41745aec8e65ca5f07a2 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 123 2.9E-25 T 13-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain THL1_RS21560 8eec7f08161e41745aec8e65ca5f07a2 130 ProSitePatterns PS00935 Glyoxalase I signature 2. 69 81 - T 13-09-2016 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|UniPathway: UPA00619 THL1_RS21560 8eec7f08161e41745aec8e65ca5f07a2 130 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 127 3.2E-65 T 13-09-2016 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|UniPathway: UPA00619 THL1_RS21560 8eec7f08161e41745aec8e65ca5f07a2 130 PANTHER PTHR10374 1 126 1.4E-61 T 13-09-2016 THL1_RS21560 8eec7f08161e41745aec8e65ca5f07a2 130 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 13-09-2016 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|UniPathway: UPA00619 THL1_RS21560 8eec7f08161e41745aec8e65ca5f07a2 130 Gene3D G3DSA:3.10.180.10 1 125 9.7E-46 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS21560 8eec7f08161e41745aec8e65ca5f07a2 130 SUPERFAMILY SSF54593 1 127 2.42E-37 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS14150 071dbdff48d100f7a82665a003f95e60 285 Pfam PF00892 EamA-like transporter family 145 274 3.7E-13 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS14150 071dbdff48d100f7a82665a003f95e60 285 Pfam PF00892 EamA-like transporter family 7 134 1.2E-6 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS14150 071dbdff48d100f7a82665a003f95e60 285 SUPERFAMILY SSF103481 42 138 5.75E-6 T 13-09-2016 THL1_RS14150 071dbdff48d100f7a82665a003f95e60 285 PANTHER PTHR32322 1 274 8.4E-45 T 13-09-2016 THL1_RS14150 071dbdff48d100f7a82665a003f95e60 285 PANTHER PTHR32322:SF9 1 274 8.4E-45 T 13-09-2016 THL1_RS14150 071dbdff48d100f7a82665a003f95e60 285 SUPERFAMILY SSF103481 184 277 1.02E-9 T 13-09-2016 THL1_RS01040 772473779bec2303e2b4a2b5654503e5 463 Pfam PF11067 Protein of unknown function (DUF2868) 151 446 4.3E-87 T 13-09-2016 IPR021296 Protein of unknown function DUF2868 THL1_RS05470 2ca4919f82c9fd58be38fe5b6e427b93 252 Gene3D G3DSA:3.40.1390.30 5 109 2.5E-35 T 13-09-2016 THL1_RS05470 2ca4919f82c9fd58be38fe5b6e427b93 252 PANTHER PTHR13799 3 247 1.1E-80 T 13-09-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 THL1_RS05470 2ca4919f82c9fd58be38fe5b6e427b93 252 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 13 240 4.4E-58 T 13-09-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 THL1_RS05470 2ca4919f82c9fd58be38fe5b6e427b93 252 Gene3D G3DSA:3.40.1390.30 110 219 3.3E-33 T 13-09-2016 THL1_RS05470 2ca4919f82c9fd58be38fe5b6e427b93 252 SUPERFAMILY SSF102705 5 251 1.31E-80 T 13-09-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 THL1_RS05470 2ca4919f82c9fd58be38fe5b6e427b93 252 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 6 250 6.8E-64 T 13-09-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 THL1_RS07790 43336796cdb305ce95390a52c7884fae 416 PANTHER PTHR13847:SF191 2 396 7.4E-136 T 13-09-2016 THL1_RS07790 43336796cdb305ce95390a52c7884fae 416 Gene3D G3DSA:3.30.9.10 226 249 6.0E-10 T 13-09-2016 THL1_RS07790 43336796cdb305ce95390a52c7884fae 416 Gene3D G3DSA:3.30.9.10 86 137 6.0E-10 T 13-09-2016 THL1_RS07790 43336796cdb305ce95390a52c7884fae 416 PANTHER PTHR13847 2 396 7.4E-136 T 13-09-2016 THL1_RS07790 43336796cdb305ce95390a52c7884fae 416 Pfam PF01266 FAD dependent oxidoreductase 3 390 2.1E-72 T 13-09-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THL1_RS07790 43336796cdb305ce95390a52c7884fae 416 Gene3D G3DSA:3.50.50.60 138 215 1.0E-34 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07790 43336796cdb305ce95390a52c7884fae 416 Gene3D G3DSA:3.50.50.60 2 84 1.0E-34 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS07790 43336796cdb305ce95390a52c7884fae 416 SUPERFAMILY SSF51905 2 283 8.2E-52 T 13-09-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THL1_RS19595 4e6396d5a70c55de2363306d3a0799cb 450 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 357 366 - T 13-09-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS19595 4e6396d5a70c55de2363306d3a0799cb 450 PANTHER PTHR15184 27 442 3.9E-231 T 13-09-2016 THL1_RS19595 4e6396d5a70c55de2363306d3a0799cb 450 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 27 443 5.1E-172 T 13-09-2016 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS19595 4e6396d5a70c55de2363306d3a0799cb 450 SMART SM00382 167 350 9.2E-5 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS19595 4e6396d5a70c55de2363306d3a0799cb 450 TIGRFAM TIGR03496 FliI_clade1: flagellar protein export ATPase FliI 29 443 3.1E-195 T 13-09-2016 IPR020005 Flagellar export ATPase FliI, clade 1 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS19595 4e6396d5a70c55de2363306d3a0799cb 450 PANTHER PTHR15184:SF9 27 442 3.9E-231 T 13-09-2016 IPR032463 ATPase, type III secretion system, FliI GO:0016887|GO:0030257|GO:0044780 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS19595 4e6396d5a70c55de2363306d3a0799cb 450 Gene3D G3DSA:3.40.50.300 130 400 3.2E-91 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS19595 4e6396d5a70c55de2363306d3a0799cb 450 SUPERFAMILY SSF52540 103 372 1.13E-96 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS19595 4e6396d5a70c55de2363306d3a0799cb 450 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 155 366 7.4E-74 T 13-09-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 THL1_RS17325 9118a00e391aee7908f4d895025b9107 235 Pfam PF04335 VirB8 protein 23 225 1.9E-66 T 13-09-2016 IPR007430 Bacterial virulence protein VirB8 GO:0016020 THL1_RS17325 9118a00e391aee7908f4d895025b9107 235 SUPERFAMILY SSF54427 93 226 7.45E-28 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS27035 cc4c96bec09a278ee94c208088bea721 220 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 91 186 4.4E-13 T 13-09-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 THL1_RS27035 cc4c96bec09a278ee94c208088bea721 220 PANTHER PTHR18901 2 197 2.3E-96 T 13-09-2016 THL1_RS27035 cc4c96bec09a278ee94c208088bea721 220 PANTHER PTHR18901:SF7 2 197 2.3E-96 T 13-09-2016 THL1_RS27035 cc4c96bec09a278ee94c208088bea721 220 SUPERFAMILY SSF56784 4 216 9.61E-45 T 13-09-2016 IPR023214 HAD-like domain THL1_RS27035 cc4c96bec09a278ee94c208088bea721 220 Gene3D G3DSA:3.40.50.1000 9 216 2.2E-29 T 13-09-2016 IPR023214 HAD-like domain THL1_RS27035 cc4c96bec09a278ee94c208088bea721 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 12 187 1.7E-13 T 13-09-2016 IPR023214 HAD-like domain THL1_RS08745 86d980390b036015512c14d5a1a10e08 290 PANTHER PTHR31964:SF41 117 274 1.3E-25 T 13-09-2016 THL1_RS08745 86d980390b036015512c14d5a1a10e08 290 SUPERFAMILY SSF52402 134 272 1.59E-13 T 13-09-2016 THL1_RS08745 86d980390b036015512c14d5a1a10e08 290 Gene3D G3DSA:3.40.50.620 119 272 4.1E-16 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS08745 86d980390b036015512c14d5a1a10e08 290 Gene3D G3DSA:3.40.50.620 2 118 3.9E-5 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS08745 86d980390b036015512c14d5a1a10e08 290 SUPERFAMILY SSF52402 2 125 8.37E-10 T 13-09-2016 THL1_RS08745 86d980390b036015512c14d5a1a10e08 290 Pfam PF00582 Universal stress protein family 170 272 5.4E-11 T 13-09-2016 IPR006016 UspA GO:0006950 THL1_RS08745 86d980390b036015512c14d5a1a10e08 290 PANTHER PTHR31964 117 274 1.3E-25 T 13-09-2016 THL1_RS00510 a238947c8258d68559d152bcec362f88 478 SUPERFAMILY SSF52467 306 477 1.16E-73 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS00510 a238947c8258d68559d152bcec362f88 478 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 475 3.3E-185 T 13-09-2016 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 THL1_RS00510 a238947c8258d68559d152bcec362f88 478 PANTHER PTHR10160 3 477 2.1E-219 T 13-09-2016 THL1_RS00510 a238947c8258d68559d152bcec362f88 478 Gene3D G3DSA:3.40.50.1220 303 477 1.4E-85 T 13-09-2016 IPR029035 DHS-like NAD/FAD-binding domain THL1_RS00510 a238947c8258d68559d152bcec362f88 478 PANTHER PTHR10160:SF24 3 477 2.1E-219 T 13-09-2016 THL1_RS00510 a238947c8258d68559d152bcec362f88 478 PIRSF PIRSF000204 1 478 7.9E-214 T 13-09-2016 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 THL1_RS16860 3a4063f1b17213173d8eebd0b6bbe069 187 PANTHER PTHR33498:SF1 1 187 3.7E-20 T 13-09-2016 THL1_RS16860 3a4063f1b17213173d8eebd0b6bbe069 187 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 30 79 6.1E-10 T 13-09-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain THL1_RS16860 3a4063f1b17213173d8eebd0b6bbe069 187 Pfam PF01610 Transposase 95 183 2.5E-25 T 13-09-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain THL1_RS16860 3a4063f1b17213173d8eebd0b6bbe069 187 PANTHER PTHR33498 1 187 3.7E-20 T 13-09-2016 THL1_RS00075 a0e79cd3ef8ebd5c85bde3916411a1a4 295 PANTHER PTHR30606:SF5 7 295 2.2E-113 T 13-09-2016 THL1_RS00075 a0e79cd3ef8ebd5c85bde3916411a1a4 295 PANTHER PTHR30606 7 295 2.2E-113 T 13-09-2016 THL1_RS00075 a0e79cd3ef8ebd5c85bde3916411a1a4 295 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 8 286 2.9E-45 T 13-09-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 THL1_RS00075 a0e79cd3ef8ebd5c85bde3916411a1a4 295 PIRSF PIRSF026649 2 295 1.6E-94 T 13-09-2016 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 THL1_RS12100 1cc53ccbe01510342bd971f652590779 297 PANTHER PTHR22911:SF37 1 293 4.0E-102 T 13-09-2016 THL1_RS12100 1cc53ccbe01510342bd971f652590779 297 Pfam PF00892 EamA-like transporter family 149 278 1.3E-16 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS12100 1cc53ccbe01510342bd971f652590779 297 SUPERFAMILY SSF103481 185 279 3.01E-11 T 13-09-2016 THL1_RS12100 1cc53ccbe01510342bd971f652590779 297 PANTHER PTHR22911 1 293 4.0E-102 T 13-09-2016 THL1_RS12100 1cc53ccbe01510342bd971f652590779 297 SUPERFAMILY SSF103481 47 137 2.62E-6 T 13-09-2016 THL1_RS01695 ee7df33ee10ec4b876fa2ed802b8b0ee 149 SMART SM01321 13 128 5.2E-33 T 13-09-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THL1_RS01695 ee7df33ee10ec4b876fa2ed802b8b0ee 149 SUPERFAMILY SSF143422 8 134 2.22E-29 T 13-09-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THL1_RS01695 ee7df33ee10ec4b876fa2ed802b8b0ee 149 PANTHER PTHR36966 1 149 4.6E-26 T 13-09-2016 THL1_RS01695 ee7df33ee10ec4b876fa2ed802b8b0ee 149 PANTHER PTHR36966:SF1 1 149 4.6E-26 T 13-09-2016 THL1_RS01695 ee7df33ee10ec4b876fa2ed802b8b0ee 149 Pfam PF01797 Transposase IS200 like 16 127 9.9E-18 T 13-09-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THL1_RS01695 ee7df33ee10ec4b876fa2ed802b8b0ee 149 Gene3D G3DSA:3.30.70.1290 3 130 6.1E-21 T 13-09-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THL1_RS13440 d0afc760b34152a1ee24d877a5564833 161 PANTHER PTHR10545 4 160 1.9E-64 T 13-09-2016 THL1_RS13440 d0afc760b34152a1ee24d877a5564833 161 Pfam PF00583 Acetyltransferase (GNAT) family 58 136 4.7E-16 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS13440 d0afc760b34152a1ee24d877a5564833 161 Gene3D G3DSA:3.40.630.30 2 157 5.3E-61 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS13440 d0afc760b34152a1ee24d877a5564833 161 SUPERFAMILY SSF55729 3 151 6.52E-39 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS02670 2d940227766422221ac8bb350e5e6b15 275 Gene3D G3DSA:1.10.3720.10 17 268 1.3E-58 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS02670 2d940227766422221ac8bb350e5e6b15 275 SUPERFAMILY SSF161098 12 268 1.5E-58 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS02670 2d940227766422221ac8bb350e5e6b15 275 PANTHER PTHR30193 6 274 1.5E-97 T 13-09-2016 THL1_RS02670 2d940227766422221ac8bb350e5e6b15 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 265 4.9E-18 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS02670 2d940227766422221ac8bb350e5e6b15 275 PANTHER PTHR30193:SF20 6 274 1.5E-97 T 13-09-2016 THL1_RS28005 feb84bcc73da0b4c1d3e70aaad532f57 324 Pfam PF01548 Transposase 5 153 6.0E-33 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS28005 feb84bcc73da0b4c1d3e70aaad532f57 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 197 280 1.9E-21 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS28005 feb84bcc73da0b4c1d3e70aaad532f57 324 PANTHER PTHR33055:SF3 1 318 1.2E-61 T 13-09-2016 THL1_RS28005 feb84bcc73da0b4c1d3e70aaad532f57 324 PANTHER PTHR33055 1 318 1.2E-61 T 13-09-2016 THL1_RS15375 feb84bcc73da0b4c1d3e70aaad532f57 324 Pfam PF01548 Transposase 5 153 6.0E-33 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS15375 feb84bcc73da0b4c1d3e70aaad532f57 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 197 280 1.9E-21 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS15375 feb84bcc73da0b4c1d3e70aaad532f57 324 PANTHER PTHR33055:SF3 1 318 1.2E-61 T 13-09-2016 THL1_RS15375 feb84bcc73da0b4c1d3e70aaad532f57 324 PANTHER PTHR33055 1 318 1.2E-61 T 13-09-2016 THL1_RS28140 feb84bcc73da0b4c1d3e70aaad532f57 324 Pfam PF01548 Transposase 5 153 6.0E-33 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS28140 feb84bcc73da0b4c1d3e70aaad532f57 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 197 280 1.9E-21 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS28140 feb84bcc73da0b4c1d3e70aaad532f57 324 PANTHER PTHR33055:SF3 1 318 1.2E-61 T 13-09-2016 THL1_RS28140 feb84bcc73da0b4c1d3e70aaad532f57 324 PANTHER PTHR33055 1 318 1.2E-61 T 13-09-2016 THL1_RS28165 feb84bcc73da0b4c1d3e70aaad532f57 324 Pfam PF01548 Transposase 5 153 6.0E-33 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS28165 feb84bcc73da0b4c1d3e70aaad532f57 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 197 280 1.9E-21 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS28165 feb84bcc73da0b4c1d3e70aaad532f57 324 PANTHER PTHR33055:SF3 1 318 1.2E-61 T 13-09-2016 THL1_RS28165 feb84bcc73da0b4c1d3e70aaad532f57 324 PANTHER PTHR33055 1 318 1.2E-61 T 13-09-2016 THL1_RS12315 f2eadbe7316597095cd94aff11e62658 531 SUPERFAMILY SSF51621 429 514 1.84E-125 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS12315 f2eadbe7316597095cd94aff11e62658 531 SUPERFAMILY SSF51621 10 392 1.84E-125 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS12315 f2eadbe7316597095cd94aff11e62658 531 PANTHER PTHR21631 96 144 2.1E-79 T 13-09-2016 THL1_RS12315 f2eadbe7316597095cd94aff11e62658 531 PANTHER PTHR21631 168 266 2.1E-79 T 13-09-2016 THL1_RS12315 f2eadbe7316597095cd94aff11e62658 531 PANTHER PTHR21631 446 531 2.1E-79 T 13-09-2016 THL1_RS12315 f2eadbe7316597095cd94aff11e62658 531 PANTHER PTHR21631 317 409 2.1E-79 T 13-09-2016 THL1_RS12315 f2eadbe7316597095cd94aff11e62658 531 Gene3D G3DSA:3.20.20.60 429 513 9.8E-136 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS12315 f2eadbe7316597095cd94aff11e62658 531 Gene3D G3DSA:3.20.20.60 303 392 9.8E-136 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS12315 f2eadbe7316597095cd94aff11e62658 531 Gene3D G3DSA:3.20.20.60 4 270 9.8E-136 T 13-09-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 THL1_RS12315 f2eadbe7316597095cd94aff11e62658 531 Pfam PF00463 Isocitrate lyase family 98 270 3.6E-20 T 13-09-2016 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969|UniPathway: UPA00703 THL1_RS12315 f2eadbe7316597095cd94aff11e62658 531 Pfam PF00463 Isocitrate lyase family 331 399 2.0E-9 T 13-09-2016 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969|UniPathway: UPA00703 THL1_RS12315 f2eadbe7316597095cd94aff11e62658 531 Pfam PF00463 Isocitrate lyase family 429 530 1.8E-13 T 13-09-2016 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969|UniPathway: UPA00703 THL1_RS20995 e86b1a1c0ecca2f035ef6867a8230e30 194 Pfam PF00510 Cytochrome c oxidase subunit III 23 192 1.1E-10 T 13-09-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 THL1_RS20995 e86b1a1c0ecca2f035ef6867a8230e30 194 SUPERFAMILY SSF81452 19 193 1.44E-43 T 13-09-2016 IPR000298 Cytochrome c oxidase subunit III domain GO:0015002|GO:0016020 THL1_RS20995 e86b1a1c0ecca2f035ef6867a8230e30 194 Gene3D G3DSA:1.20.120.80 18 193 1.5E-44 T 13-09-2016 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 THL1_RS20995 e86b1a1c0ecca2f035ef6867a8230e30 194 PANTHER PTHR11403:SF6 19 194 3.0E-45 T 13-09-2016 THL1_RS20995 e86b1a1c0ecca2f035ef6867a8230e30 194 PANTHER PTHR11403 19 194 3.0E-45 T 13-09-2016 IPR024791 Cytochrome c oxidase subunit III GO:0015002|GO:0016020|GO:0019646 THL1_RS02275 5511abc6bee541da63f53d5f87740f82 450 PANTHER PTHR20852:SF7 13 450 8.5E-83 T 13-09-2016 THL1_RS02275 5511abc6bee541da63f53d5f87740f82 450 Gene3D G3DSA:3.30.590.10 124 439 4.2E-76 T 13-09-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 THL1_RS02275 5511abc6bee541da63f53d5f87740f82 450 SMART SM01230 121 373 2.4E-80 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS02275 5511abc6bee541da63f53d5f87740f82 450 Pfam PF00120 Glutamine synthetase, catalytic domain 123 449 8.2E-79 T 13-09-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS02275 5511abc6bee541da63f53d5f87740f82 450 PANTHER PTHR20852 13 450 8.5E-83 T 13-09-2016 THL1_RS02275 5511abc6bee541da63f53d5f87740f82 450 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 257 272 - T 13-09-2016 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THL1_RS02275 5511abc6bee541da63f53d5f87740f82 450 SUPERFAMILY SSF55931 121 450 4.27E-85 T 13-09-2016 THL1_RS01005 261782050604f61c755dc6b77afbd044 250 PANTHER PTHR17985 2 237 1.0E-73 T 13-09-2016 IPR008551 Transport and Golgi organisation protein 2 THL1_RS01005 261782050604f61c755dc6b77afbd044 250 Pfam PF05742 Transport and Golgi organisation 2 1 234 3.8E-59 T 13-09-2016 IPR008551 Transport and Golgi organisation protein 2 THL1_RS22930 236cf05a8d3d9d696a37a9a2039a0665 478 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 67 207 2.7E-16 T 13-09-2016 THL1_RS22930 236cf05a8d3d9d696a37a9a2039a0665 478 PANTHER PTHR33908:SF3 14 374 1.8E-55 T 13-09-2016 THL1_RS22930 236cf05a8d3d9d696a37a9a2039a0665 478 PANTHER PTHR33908 14 374 1.8E-55 T 13-09-2016 THL1_RS04735 0f26a7eba1f3d92ff9ae19144e1aa209 688 PANTHER PTHR30252 9 688 0.0 T 13-09-2016 THL1_RS04735 0f26a7eba1f3d92ff9ae19144e1aa209 688 PANTHER PTHR30252:SF3 9 688 0.0 T 13-09-2016 THL1_RS04735 0f26a7eba1f3d92ff9ae19144e1aa209 688 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 466 594 4.2E-36 T 13-09-2016 IPR025299 CstA, C-terminal domain THL1_RS04735 0f26a7eba1f3d92ff9ae19144e1aa209 688 Pfam PF02554 Carbon starvation protein CstA 35 411 2.5E-166 T 13-09-2016 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 THL1_RS02260 5870d84f83a46e605447c1573515fc65 324 Gene3D G3DSA:2.60.40.1090 196 324 1.3E-12 T 13-09-2016 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 THL1_RS02260 5870d84f83a46e605447c1573515fc65 324 Pfam PF00419 Fimbrial protein 185 323 9.8E-13 T 13-09-2016 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 THL1_RS02260 5870d84f83a46e605447c1573515fc65 324 SUPERFAMILY SSF49401 196 324 1.44E-13 T 13-09-2016 IPR008966 Adhesion domain THL1_RS26960 19bd0127fe8c1ed1b77900cdc0f3ce22 650 SUPERFAMILY SSF52540 1 367 4.39E-17 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26960 19bd0127fe8c1ed1b77900cdc0f3ce22 650 Gene3D G3DSA:3.40.50.300 1 183 1.9E-17 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26960 19bd0127fe8c1ed1b77900cdc0f3ce22 650 Gene3D G3DSA:3.40.50.300 233 386 1.9E-17 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26960 19bd0127fe8c1ed1b77900cdc0f3ce22 650 Pfam PF13175 AAA ATPase domain 1 363 7.4E-51 T 13-09-2016 THL1_RS06920 57c2e39669c21fcc741b64ffca90f055 369 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 89 185 3.4E-9 T 13-09-2016 IPR018712 Domain of unknown function DUF2235 THL1_RS01930 a9ea52c1bc4bdf7ae86e6a35cebc13b1 403 Pfam PF00557 Metallopeptidase family M24 166 382 5.7E-25 T 13-09-2016 IPR000994 Peptidase M24, structural domain THL1_RS01930 a9ea52c1bc4bdf7ae86e6a35cebc13b1 403 PANTHER PTHR10804:SF99 1 402 9.1E-180 T 13-09-2016 THL1_RS01930 a9ea52c1bc4bdf7ae86e6a35cebc13b1 403 Pfam PF01321 Creatinase/Prolidase N-terminal domain 27 158 1.9E-17 T 13-09-2016 IPR000587 Creatinase, N-terminal GO:0016787 THL1_RS01930 a9ea52c1bc4bdf7ae86e6a35cebc13b1 403 SUPERFAMILY SSF53092 3 156 3.14E-48 T 13-09-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal THL1_RS01930 a9ea52c1bc4bdf7ae86e6a35cebc13b1 403 SUPERFAMILY SSF55920 157 397 6.28E-61 T 13-09-2016 IPR000994 Peptidase M24, structural domain THL1_RS01930 a9ea52c1bc4bdf7ae86e6a35cebc13b1 403 Gene3D G3DSA:3.90.230.10 157 397 1.4E-45 T 13-09-2016 IPR000994 Peptidase M24, structural domain THL1_RS01930 a9ea52c1bc4bdf7ae86e6a35cebc13b1 403 PANTHER PTHR10804 1 402 9.1E-180 T 13-09-2016 THL1_RS01930 a9ea52c1bc4bdf7ae86e6a35cebc13b1 403 Gene3D G3DSA:3.40.350.10 3 156 1.4E-55 T 13-09-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal THL1_RS23115 db155129140b7abc8e5fd79b8f178381 70 Pfam PF06945 Protein of unknown function (DUF1289) 10 55 1.5E-18 T 13-09-2016 IPR010710 Protein of unknown function DUF1289 THL1_RS23115 db155129140b7abc8e5fd79b8f178381 70 PANTHER PTHR35175:SF2 5 61 8.4E-19 T 13-09-2016 THL1_RS23115 db155129140b7abc8e5fd79b8f178381 70 PANTHER PTHR35175 5 61 8.4E-19 T 13-09-2016 THL1_RS04250 15a31915ef81d0bb95d3ce441b088ad2 387 SUPERFAMILY SSF56601 8 277 1.47E-89 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS04250 15a31915ef81d0bb95d3ce441b088ad2 387 Gene3D G3DSA:3.40.710.10 29 276 1.2E-101 T 13-09-2016 IPR012338 Beta-lactamase/transpeptidase-like THL1_RS04250 15a31915ef81d0bb95d3ce441b088ad2 387 PANTHER PTHR21581 24 387 3.2E-122 T 13-09-2016 THL1_RS04250 15a31915ef81d0bb95d3ce441b088ad2 387 SMART SM00936 277 367 1.5E-32 T 13-09-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS04250 15a31915ef81d0bb95d3ce441b088ad2 387 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 277 367 8.4E-24 T 13-09-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS04250 15a31915ef81d0bb95d3ce441b088ad2 387 SUPERFAMILY SSF69189 277 369 2.94E-24 T 13-09-2016 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS04250 15a31915ef81d0bb95d3ce441b088ad2 387 Gene3D G3DSA:2.60.410.10 277 367 1.3E-27 T 13-09-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 THL1_RS04250 15a31915ef81d0bb95d3ce441b088ad2 387 PANTHER PTHR21581:SF3 24 387 3.2E-122 T 13-09-2016 THL1_RS04250 15a31915ef81d0bb95d3ce441b088ad2 387 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 29 256 3.3E-86 T 13-09-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 THL1_RS04250 15a31915ef81d0bb95d3ce441b088ad2 387 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 144 157 5.0E-18 T 13-09-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THL1_RS04250 15a31915ef81d0bb95d3ce441b088ad2 387 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 64 75 5.0E-18 T 13-09-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THL1_RS04250 15a31915ef81d0bb95d3ce441b088ad2 387 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 117 134 5.0E-18 T 13-09-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THL1_RS19725 f3fd961c42a920c97ce710c8aae2a6f2 234 Pfam PF02525 Flavodoxin-like fold 1 208 2.0E-54 T 13-09-2016 IPR003680 Flavodoxin-like fold THL1_RS19725 f3fd961c42a920c97ce710c8aae2a6f2 234 SUPERFAMILY SSF52218 1 231 2.1E-69 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS19725 f3fd961c42a920c97ce710c8aae2a6f2 234 PANTHER PTHR10204:SF46 1 230 1.2E-140 T 13-09-2016 THL1_RS19725 f3fd961c42a920c97ce710c8aae2a6f2 234 PANTHER PTHR10204 1 230 1.2E-140 T 13-09-2016 THL1_RS19725 f3fd961c42a920c97ce710c8aae2a6f2 234 Gene3D G3DSA:3.40.50.360 1 226 1.6E-71 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS01550 d3ea47504d39c1ba44859108de01a71f 339 Gene3D G3DSA:3.40.50.180 150 335 1.2E-43 T 13-09-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS01550 d3ea47504d39c1ba44859108de01a71f 339 PANTHER PTHR24421 122 318 8.7E-59 T 13-09-2016 THL1_RS01550 d3ea47504d39c1ba44859108de01a71f 339 SUPERFAMILY SSF52738 150 334 1.31E-42 T 13-09-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS01550 d3ea47504d39c1ba44859108de01a71f 339 Pfam PF01339 CheB methylesterase 155 330 2.7E-37 T 13-09-2016 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 THL1_RS01550 d3ea47504d39c1ba44859108de01a71f 339 PANTHER PTHR24421:SF21 122 318 8.7E-59 T 13-09-2016 THL1_RS00795 93460d0a40a49461d40ad400161d2101 99 TIGRFAM TIGR03130 malonate_delta: malonate decarboxylase acyl carrier protein 2 95 1.6E-34 T 13-09-2016 IPR009662 Malonate decarboxylase delta subunit THL1_RS00795 93460d0a40a49461d40ad400161d2101 99 Hamap MF_00710 Malonate decarboxylase acyl carrier protein [mdcC]. 1 99 55.427 T 13-09-2016 IPR009662 Malonate decarboxylase delta subunit THL1_RS00795 93460d0a40a49461d40ad400161d2101 99 Pfam PF06857 Malonate decarboxylase delta subunit (MdcD) 17 95 1.1E-24 T 13-09-2016 IPR023439 Malonate decarboxylase/citrate lyase acyl carrier protein THL1_RS00795 93460d0a40a49461d40ad400161d2101 99 ProDom PD015450 MALONATE DECARBOXYLASE SUBUNIT DELTA ACYL CARRIER DECARBOXYLASE PLASMID DIRECT SEQUENCING 1 94 9.0E-40 T 13-09-2016 IPR009662 Malonate decarboxylase delta subunit THL1_RS06670 aea4aeb33f3981f1fadcaeffda919fb9 243 Gene3D G3DSA:3.40.190.10 35 118 2.6E-9 T 13-09-2016 THL1_RS06670 aea4aeb33f3981f1fadcaeffda919fb9 243 Gene3D G3DSA:3.40.190.10 119 184 1.0E-9 T 13-09-2016 THL1_RS06670 aea4aeb33f3981f1fadcaeffda919fb9 243 SUPERFAMILY SSF53850 6 233 1.63E-31 T 13-09-2016 THL1_RS06670 aea4aeb33f3981f1fadcaeffda919fb9 243 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 231 7.8E-13 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS06670 aea4aeb33f3981f1fadcaeffda919fb9 243 SMART SM00062 14 238 0.0044 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS15530 8ceb4a1b20f2603988354da956ac0772 453 Gene3D G3DSA:2.50.20.10 158 304 2.3E-48 T 13-09-2016 THL1_RS15530 8ceb4a1b20f2603988354da956ac0772 453 Gene3D G3DSA:2.50.20.10 337 449 2.3E-48 T 13-09-2016 THL1_RS15530 8ceb4a1b20f2603988354da956ac0772 453 Pfam PF07044 Protein of unknown function (DUF1329) 82 448 4.6E-127 T 13-09-2016 IPR010752 Protein of unknown function DUF1329 THL1_RS22545 ae00fbb407de585ea90b84f879b9d847 281 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 18 273 6.8E-117 T 13-09-2016 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 THL1_RS22545 ae00fbb407de585ea90b84f879b9d847 281 PANTHER PTHR21057 1 281 5.4E-212 T 13-09-2016 THL1_RS22545 ae00fbb407de585ea90b84f879b9d847 281 SUPERFAMILY SSF51569 3 276 2.75E-103 T 13-09-2016 THL1_RS22545 ae00fbb407de585ea90b84f879b9d847 281 Pfam PF00793 DAHP synthetase I family 10 273 2.4E-76 T 13-09-2016 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 THL1_RS22545 ae00fbb407de585ea90b84f879b9d847 281 PANTHER PTHR21057:SF6 1 281 5.4E-212 T 13-09-2016 THL1_RS22545 ae00fbb407de585ea90b84f879b9d847 281 Gene3D G3DSA:3.20.20.70 16 276 2.9E-108 T 13-09-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 THL1_RS22545 ae00fbb407de585ea90b84f879b9d847 281 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 13 275 49.236 T 13-09-2016 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008152|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 THL1_RS26025 8115807631325fdd5c616426fdccedea 196 Pfam PF07883 Cupin domain 124 190 6.6E-21 T 13-09-2016 IPR013096 Cupin 2, conserved barrel THL1_RS26025 8115807631325fdd5c616426fdccedea 196 SUPERFAMILY SSF51182 68 196 9.96E-30 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS26025 8115807631325fdd5c616426fdccedea 196 Pfam PF01381 Helix-turn-helix 21 75 1.0E-12 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS26025 8115807631325fdd5c616426fdccedea 196 SMART SM00530 20 75 3.1E-14 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS26025 8115807631325fdd5c616426fdccedea 196 PANTHER PTHR10245:SF49 13 196 5.6E-57 T 13-09-2016 THL1_RS26025 8115807631325fdd5c616426fdccedea 196 Gene3D G3DSA:2.60.120.10 70 195 7.8E-27 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS26025 8115807631325fdd5c616426fdccedea 196 Gene3D G3DSA:1.10.260.40 12 69 2.7E-21 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS26025 8115807631325fdd5c616426fdccedea 196 SUPERFAMILY SSF47413 15 79 1.8E-17 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS26025 8115807631325fdd5c616426fdccedea 196 PANTHER PTHR10245 13 196 5.6E-57 T 13-09-2016 THL1_RS22050 6dfcbfc470c61416a1aef7784ed633b0 356 PANTHER PTHR21716 6 347 7.4E-140 T 13-09-2016 IPR002549 Transmembrane protein TqsA-like THL1_RS22050 6dfcbfc470c61416a1aef7784ed633b0 356 PANTHER PTHR21716:SF19 6 347 7.4E-140 T 13-09-2016 THL1_RS22050 6dfcbfc470c61416a1aef7784ed633b0 356 Pfam PF01594 Domain of unknown function DUF20 20 345 4.0E-71 T 13-09-2016 IPR002549 Transmembrane protein TqsA-like THL1_RS10185 3fdd423411b6eb1bb22779cd2308d17a 174 SUPERFAMILY SSF103054 98 170 1.7E-12 T 13-09-2016 IPR023229 Type II secretion system protein M, periplasmic domain THL1_RS10185 3fdd423411b6eb1bb22779cd2308d17a 174 Gene3D G3DSA:3.30.1360.100 98 170 8.9E-13 T 13-09-2016 IPR023229 Type II secretion system protein M, periplasmic domain THL1_RS10185 3fdd423411b6eb1bb22779cd2308d17a 174 Pfam PF04612 Type II secretion system (T2SS), protein M 20 170 1.3E-38 T 13-09-2016 IPR007690 Type II secretion system, protein M GO:0006858 THL1_RS24420 83e49e5d5734b6d16ec68c81514c09e6 127 Pfam PF03840 Preprotein translocase SecG subunit 5 74 1.7E-19 T 13-09-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THL1_RS24420 83e49e5d5734b6d16ec68c81514c09e6 127 PRINTS PR01651 Protein-export SecG membrane protein signature 4 24 1.2E-41 T 13-09-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THL1_RS24420 83e49e5d5734b6d16ec68c81514c09e6 127 PRINTS PR01651 Protein-export SecG membrane protein signature 24 38 1.2E-41 T 13-09-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THL1_RS24420 83e49e5d5734b6d16ec68c81514c09e6 127 PRINTS PR01651 Protein-export SecG membrane protein signature 39 55 1.2E-41 T 13-09-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THL1_RS24420 83e49e5d5734b6d16ec68c81514c09e6 127 PRINTS PR01651 Protein-export SecG membrane protein signature 55 77 1.2E-41 T 13-09-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THL1_RS24420 83e49e5d5734b6d16ec68c81514c09e6 127 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 4 74 8.9E-25 T 13-09-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THL1_RS24420 83e49e5d5734b6d16ec68c81514c09e6 127 PANTHER PTHR34182 3 124 1.6E-29 T 13-09-2016 THL1_RS00855 e54fbd78ad875d580b3e3797bf1e184a 81 Gene3D G3DSA:3.30.70.20 16 75 2.8E-16 T 13-09-2016 THL1_RS00855 e54fbd78ad875d580b3e3797bf1e184a 81 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 57 68 - T 13-09-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THL1_RS00855 e54fbd78ad875d580b3e3797bf1e184a 81 Pfam PF13187 4Fe-4S dicluster domain 28 71 4.4E-8 T 13-09-2016 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THL1_RS00855 e54fbd78ad875d580b3e3797bf1e184a 81 SUPERFAMILY SSF54862 9 74 1.29E-14 T 13-09-2016 THL1_RS11900 d1714e60ed00774d8edc43b08e7e6999 611 Pfam PF07731 Multicopper oxidase 489 598 7.8E-15 T 13-09-2016 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 THL1_RS11900 d1714e60ed00774d8edc43b08e7e6999 611 Gene3D G3DSA:2.60.40.420 115 269 5.5E-11 T 13-09-2016 IPR008972 Cupredoxin THL1_RS11900 d1714e60ed00774d8edc43b08e7e6999 611 SUPERFAMILY SSF49503 114 271 4.73E-10 T 13-09-2016 IPR008972 Cupredoxin THL1_RS11900 d1714e60ed00774d8edc43b08e7e6999 611 ProSitePatterns PS00080 Multicopper oxidases signature 2. 579 590 - T 13-09-2016 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 THL1_RS11900 d1714e60ed00774d8edc43b08e7e6999 611 SUPERFAMILY SSF49503 295 354 2.72E-20 T 13-09-2016 IPR008972 Cupredoxin THL1_RS11900 d1714e60ed00774d8edc43b08e7e6999 611 SUPERFAMILY SSF49503 520 605 2.72E-20 T 13-09-2016 IPR008972 Cupredoxin THL1_RS11900 d1714e60ed00774d8edc43b08e7e6999 611 Gene3D G3DSA:2.60.40.420 476 598 3.7E-23 T 13-09-2016 IPR008972 Cupredoxin THL1_RS11900 d1714e60ed00774d8edc43b08e7e6999 611 Gene3D G3DSA:2.60.40.420 285 407 3.6E-22 T 13-09-2016 IPR008972 Cupredoxin THL1_RS11900 d1714e60ed00774d8edc43b08e7e6999 611 PANTHER PTHR11709 241 599 1.3E-53 T 13-09-2016 THL1_RS11900 d1714e60ed00774d8edc43b08e7e6999 611 PANTHER PTHR11709 125 218 1.3E-53 T 13-09-2016 THL1_RS11900 d1714e60ed00774d8edc43b08e7e6999 611 PANTHER PTHR11709:SF2 125 218 1.3E-53 T 13-09-2016 THL1_RS11900 d1714e60ed00774d8edc43b08e7e6999 611 PANTHER PTHR11709:SF2 241 599 1.3E-53 T 13-09-2016 THL1_RS28095 807d1282fd38b26733a352dcbd9fec81 95 Pfam PF13586 Transposase DDE domain 9 90 1.5E-10 T 13-09-2016 IPR025668 Transposase DDE domain THL1_RS01555 9079cee6dfee4e3c82acdebdc5f11cd6 156 SUPERFAMILY SSF50341 9 89 2.75E-7 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS01555 9079cee6dfee4e3c82acdebdc5f11cd6 156 SMART SM00260 11 147 0.002 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS01555 9079cee6dfee4e3c82acdebdc5f11cd6 156 Pfam PF01584 CheW-like domain 16 113 2.2E-7 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS17235 2389a89428d9827b6b6d49e0bc97eb93 797 SUPERFAMILY SSF82866 572 784 1.7E-33 T 13-09-2016 THL1_RS17235 2389a89428d9827b6b6d49e0bc97eb93 797 Gene3D G3DSA:1.20.1640.10 585 786 6.4E-31 T 13-09-2016 THL1_RS17235 2389a89428d9827b6b6d49e0bc97eb93 797 Gene3D G3DSA:1.20.1640.10 200 387 3.6E-27 T 13-09-2016 THL1_RS17235 2389a89428d9827b6b6d49e0bc97eb93 797 Pfam PF03176 MMPL family 578 782 3.1E-14 T 13-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 THL1_RS17235 2389a89428d9827b6b6d49e0bc97eb93 797 Pfam PF03176 MMPL family 165 417 3.0E-6 T 13-09-2016 IPR004869 Membrane transport protein, MMPL domain GO:0016020 THL1_RS17235 2389a89428d9827b6b6d49e0bc97eb93 797 SUPERFAMILY SSF82866 183 386 3.79E-27 T 13-09-2016 THL1_RS17235 2389a89428d9827b6b6d49e0bc97eb93 797 PANTHER PTHR33406 1 102 3.0E-42 T 13-09-2016 THL1_RS17235 2389a89428d9827b6b6d49e0bc97eb93 797 PANTHER PTHR33406 126 783 3.0E-42 T 13-09-2016 THL1_RS26290 80ed99b4a8f32fb362f134fd53c860d1 367 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 350 8.3E-116 T 13-09-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 THL1_RS26290 80ed99b4a8f32fb362f134fd53c860d1 367 PANTHER PTHR21090 1 359 2.1E-199 T 13-09-2016 THL1_RS26290 80ed99b4a8f32fb362f134fd53c860d1 367 Gene3D G3DSA:1.20.1090.10 171 354 2.6E-63 T 13-09-2016 THL1_RS26290 80ed99b4a8f32fb362f134fd53c860d1 367 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 356 42.754 T 13-09-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 THL1_RS26290 80ed99b4a8f32fb362f134fd53c860d1 367 PIRSF PIRSF001455 5 361 1.9E-104 T 13-09-2016 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 THL1_RS26290 80ed99b4a8f32fb362f134fd53c860d1 367 Pfam PF01761 3-dehydroquinate synthase 65 323 1.6E-105 T 13-09-2016 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 THL1_RS26290 80ed99b4a8f32fb362f134fd53c860d1 367 SUPERFAMILY SSF56796 3 354 2.36E-117 T 13-09-2016 THL1_RS26290 80ed99b4a8f32fb362f134fd53c860d1 367 Gene3D G3DSA:3.40.50.1970 2 169 6.9E-68 T 13-09-2016 THL1_RS22515 377a944c1fee06fffce562b4466c8f0d 281 Gene3D G3DSA:3.40.50.1820 2 280 6.2E-82 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS22515 377a944c1fee06fffce562b4466c8f0d 281 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 4 279 9.1E-127 T 13-09-2016 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801 THL1_RS22515 377a944c1fee06fffce562b4466c8f0d 281 Pfam PF00756 Putative esterase 23 273 3.8E-66 T 13-09-2016 IPR000801 Putative esterase THL1_RS22515 377a944c1fee06fffce562b4466c8f0d 281 PANTHER PTHR10061 2 281 5.2E-183 T 13-09-2016 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801 THL1_RS22515 377a944c1fee06fffce562b4466c8f0d 281 SUPERFAMILY SSF53474 3 280 2.77E-95 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS09400 43895e37cc96840bcd62d0168f9ce9d5 303 Gene3D G3DSA:1.10.3430.10 5 295 4.8E-69 T 13-09-2016 IPR029020 Ammonium/urea transporter THL1_RS09400 43895e37cc96840bcd62d0168f9ce9d5 303 PIRSF PIRSF016502 2 300 4.7E-61 T 13-09-2016 IPR004937 Urea transporter GO:0015204|GO:0016021|GO:0071918 Reactome: REACT_15518|Reactome: REACT_20679 THL1_RS09400 43895e37cc96840bcd62d0168f9ce9d5 303 Pfam PF03253 Urea transporter 16 288 8.2E-63 T 13-09-2016 IPR004937 Urea transporter GO:0015204|GO:0016021|GO:0071918 Reactome: REACT_15518|Reactome: REACT_20679 THL1_RS09400 43895e37cc96840bcd62d0168f9ce9d5 303 PANTHER PTHR10464 16 285 2.2E-47 T 13-09-2016 IPR004937 Urea transporter GO:0015204|GO:0016021|GO:0071918 Reactome: REACT_15518|Reactome: REACT_20679 THL1_RS12235 6d6a9cac282e90e3dfe5151e7eee9d9c 161 PANTHER PTHR37465 1 91 4.8E-15 T 13-09-2016 THL1_RS12235 6d6a9cac282e90e3dfe5151e7eee9d9c 161 PANTHER PTHR37465:SF1 1 91 4.8E-15 T 13-09-2016 THL1_RS12235 6d6a9cac282e90e3dfe5151e7eee9d9c 161 Pfam PF05488 PAAR motif 10 66 2.6E-6 T 13-09-2016 IPR008727 PAAR motif THL1_RS00495 3d82f5319e653ee092277d585bef4bd1 69 Pfam PF06568 Domain of unknown function (DUF1127) 24 59 2.1E-13 T 13-09-2016 IPR009506 Protein of unknown function DUF1127 THL1_RS06910 7a3a5ef65ed1bc123fbabea33bd73741 219 Pfam PF11153 Protein of unknown function (DUF2931) 5 217 7.8E-31 T 13-09-2016 IPR021326 Protein of unknown function DUF2931 THL1_RS16305 3075008d521802c8bb7508f110f25fb3 95 Pfam PF04606 Ogr/Delta-like zinc finger 8 52 1.8E-15 T 13-09-2016 IPR007684 Zinc finger, Ogr/Delta-type THL1_RS04175 43a35c7a36ccaaea74fa973bdacbfafc 120 PANTHER PTHR33931 1 118 3.9E-35 T 13-09-2016 THL1_RS04175 43a35c7a36ccaaea74fa973bdacbfafc 120 PANTHER PTHR33931:SF2 1 118 3.9E-35 T 13-09-2016 THL1_RS04175 43a35c7a36ccaaea74fa973bdacbfafc 120 Pfam PF03788 LrgA family 13 106 4.6E-20 T 13-09-2016 IPR005538 LrgA/CidA family GO:0016021 THL1_RS18940 05443efe21c1a0ebab71ece43830a457 235 Gene3D G3DSA:1.10.357.10 21 223 4.2E-22 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS18940 05443efe21c1a0ebab71ece43830a457 235 PANTHER PTHR30055:SF39 7 88 3.8E-53 T 13-09-2016 THL1_RS18940 05443efe21c1a0ebab71ece43830a457 235 PANTHER PTHR30055:SF39 109 230 3.8E-53 T 13-09-2016 THL1_RS18940 05443efe21c1a0ebab71ece43830a457 235 PANTHER PTHR30055 7 88 3.8E-53 T 13-09-2016 THL1_RS18940 05443efe21c1a0ebab71ece43830a457 235 PANTHER PTHR30055 109 230 3.8E-53 T 13-09-2016 THL1_RS18940 05443efe21c1a0ebab71ece43830a457 235 SUPERFAMILY SSF46689 22 83 7.28E-11 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS18940 05443efe21c1a0ebab71ece43830a457 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 67 1.6E-6 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS21760 72ef06aa4911d96fa07819f18408dbe0 477 PANTHER PTHR30203 3 470 4.3E-175 T 13-09-2016 THL1_RS21760 72ef06aa4911d96fa07819f18408dbe0 477 SUPERFAMILY SSF56954 3 30 4.45E-116 T 13-09-2016 THL1_RS21760 72ef06aa4911d96fa07819f18408dbe0 477 SUPERFAMILY SSF56954 57 468 4.45E-116 T 13-09-2016 THL1_RS21760 72ef06aa4911d96fa07819f18408dbe0 477 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 9 466 1.8E-144 T 13-09-2016 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0005215|GO:0006810|GO:0008289|GO:0016020 THL1_RS21760 72ef06aa4911d96fa07819f18408dbe0 477 Gene3D G3DSA:2.20.200.10 102 143 2.6E-23 T 13-09-2016 THL1_RS21760 72ef06aa4911d96fa07819f18408dbe0 477 Gene3D G3DSA:2.20.200.10 316 351 2.6E-23 T 13-09-2016 THL1_RS21760 72ef06aa4911d96fa07819f18408dbe0 477 PANTHER PTHR30203:SF15 3 470 4.3E-175 T 13-09-2016 THL1_RS21760 72ef06aa4911d96fa07819f18408dbe0 477 Pfam PF02321 Outer membrane efflux protein 66 256 9.6E-25 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS21760 72ef06aa4911d96fa07819f18408dbe0 477 Pfam PF02321 Outer membrane efflux protein 284 464 4.2E-27 T 13-09-2016 IPR003423 Outer membrane efflux protein GO:0005215|GO:0006810 THL1_RS21760 72ef06aa4911d96fa07819f18408dbe0 477 Gene3D G3DSA:1.20.1600.10 144 315 1.9E-102 T 13-09-2016 THL1_RS21760 72ef06aa4911d96fa07819f18408dbe0 477 Gene3D G3DSA:1.20.1600.10 54 92 1.9E-102 T 13-09-2016 THL1_RS21760 72ef06aa4911d96fa07819f18408dbe0 477 Gene3D G3DSA:1.20.1600.10 353 467 1.9E-102 T 13-09-2016 THL1_RS00945 1afec50be51939193b494b6e1aed2d90 292 SUPERFAMILY SSF56317 3 282 1.18E-80 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS00945 1afec50be51939193b494b6e1aed2d90 292 Gene3D G3DSA:3.60.110.10 3 283 1.2E-92 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS00945 1afec50be51939193b494b6e1aed2d90 292 PANTHER PTHR23088:SF26 3 286 1.4E-152 T 13-09-2016 THL1_RS00945 1afec50be51939193b494b6e1aed2d90 292 Pfam PF00795 Carbon-nitrogen hydrolase 6 266 9.4E-51 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS00945 1afec50be51939193b494b6e1aed2d90 292 TIGRFAM TIGR03381 agmatine_aguB: N-carbamoylputrescine amidase 5 282 8.8E-147 T 13-09-2016 IPR017755 N-carbamoylputrescine amidase GO:0006596|GO:0050126 KEGG: 00330+3.5.1.53|MetaCyc: PWY-43|UniPathway: UPA00534 THL1_RS00945 1afec50be51939193b494b6e1aed2d90 292 PANTHER PTHR23088 3 286 1.4E-152 T 13-09-2016 THL1_RS06475 8f53a0782add7cc8881948aa84db1e6a 187 PANTHER PTHR11839:SF12 2 180 2.9E-56 T 13-09-2016 THL1_RS06475 8f53a0782add7cc8881948aa84db1e6a 187 PRINTS PR00502 NUDIX hydrolase family signature 73 87 9.7E-5 T 13-09-2016 IPR020476 NUDIX hydrolase THL1_RS06475 8f53a0782add7cc8881948aa84db1e6a 187 PRINTS PR00502 NUDIX hydrolase family signature 87 102 9.7E-5 T 13-09-2016 IPR020476 NUDIX hydrolase THL1_RS06475 8f53a0782add7cc8881948aa84db1e6a 187 SUPERFAMILY SSF55811 6 177 7.18E-36 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS06475 8f53a0782add7cc8881948aa84db1e6a 187 Pfam PF00293 NUDIX domain 46 153 3.7E-14 T 13-09-2016 IPR000086 NUDIX hydrolase domain GO:0016787 THL1_RS06475 8f53a0782add7cc8881948aa84db1e6a 187 PANTHER PTHR11839 2 180 2.9E-56 T 13-09-2016 THL1_RS06475 8f53a0782add7cc8881948aa84db1e6a 187 Gene3D G3DSA:3.90.79.10 6 177 3.6E-38 T 13-09-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 THL1_RS06475 8f53a0782add7cc8881948aa84db1e6a 187 ProSitePatterns PS00893 Nudix box signature. 78 99 - T 13-09-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THL1_RS16885 09f8d94fa2a9bac37b69b5dec6010bdf 62 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 44 9.1E-5 T 13-09-2016 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 THL1_RS16885 09f8d94fa2a9bac37b69b5dec6010bdf 62 Gene3D G3DSA:1.10.1220.10 2 46 1.4E-10 T 13-09-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THL1_RS16885 09f8d94fa2a9bac37b69b5dec6010bdf 62 SUPERFAMILY SSF47598 3 46 8.9E-10 T 13-09-2016 IPR010985 Ribbon-helix-helix GO:0006355 THL1_RS05300 47ea9d09e877d9e610ecdc1c7571074a 329 Pfam PF04085 rod shape-determining protein MreC 99 244 1.2E-35 T 13-09-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 THL1_RS05300 47ea9d09e877d9e610ecdc1c7571074a 329 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 1 249 1.8E-61 T 13-09-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 THL1_RS05300 47ea9d09e877d9e610ecdc1c7571074a 329 PANTHER PTHR34138 1 321 3.5E-76 T 13-09-2016 THL1_RS05300 47ea9d09e877d9e610ecdc1c7571074a 329 PANTHER PTHR34138:SF1 1 321 3.5E-76 T 13-09-2016 THL1_RS16950 ebbf634781955103158f76e6afcc3b9e 227 PANTHER PTHR30060 1 198 1.1E-46 T 13-09-2016 THL1_RS16950 ebbf634781955103158f76e6afcc3b9e 227 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 12 186 1.3E-71 T 13-09-2016 IPR022301 Integral membrane protein YjbE THL1_RS16950 ebbf634781955103158f76e6afcc3b9e 227 Pfam PF03741 Integral membrane protein TerC family 15 184 2.5E-45 T 13-09-2016 IPR005496 Integral membrane protein TerC GO:0016021 THL1_RS20480 7471aa4ca63f1825fbec8405681a1744 363 PANTHER PTHR30011 1 361 1.2E-39 T 13-09-2016 THL1_RS20480 7471aa4ca63f1825fbec8405681a1744 363 Pfam PF00296 Luciferase-like monooxygenase 4 326 2.3E-27 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS20480 7471aa4ca63f1825fbec8405681a1744 363 PANTHER PTHR30011:SF6 1 361 1.2E-39 T 13-09-2016 THL1_RS20480 7471aa4ca63f1825fbec8405681a1744 363 Gene3D G3DSA:3.20.20.30 1 361 2.8E-60 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS20480 7471aa4ca63f1825fbec8405681a1744 363 SUPERFAMILY SSF51679 1 361 2.75E-59 T 13-09-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 THL1_RS24635 836ef016f62a7c54354bf18cafb37581 137 SUPERFAMILY SSF50346 15 134 7.65E-23 T 13-09-2016 IPR011033 PRC-barrel-like THL1_RS24635 836ef016f62a7c54354bf18cafb37581 137 PANTHER PTHR36505 25 137 8.3E-35 T 13-09-2016 THL1_RS24635 836ef016f62a7c54354bf18cafb37581 137 PANTHER PTHR36505:SF1 25 137 8.3E-35 T 13-09-2016 THL1_RS24635 836ef016f62a7c54354bf18cafb37581 137 Gene3D G3DSA:2.30.30.240 28 87 6.6E-19 T 13-09-2016 THL1_RS24635 836ef016f62a7c54354bf18cafb37581 137 Pfam PF05239 PRC-barrel domain 31 100 3.9E-15 T 13-09-2016 IPR027275 PRC-barrel domain THL1_RS11465 d3501f6012af981b4e54b9937b410342 123 Pfam PF05951 Bacterial protein of unknown function (DUF882) 3 98 1.1E-22 T 13-09-2016 IPR010275 Protein of unknown function DUF882 THL1_RS11465 d3501f6012af981b4e54b9937b410342 123 PANTHER PTHR37425 1 99 2.2E-16 T 13-09-2016 THL1_RS11465 d3501f6012af981b4e54b9937b410342 123 SUPERFAMILY SSF55166 2 100 8.04E-29 T 13-09-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain THL1_RS11465 d3501f6012af981b4e54b9937b410342 123 Gene3D G3DSA:3.30.1380.10 4 100 1.2E-26 T 13-09-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain THL1_RS19760 6ce2a351327b1f1a7d0c0313d3e63205 472 Gene3D G3DSA:3.40.605.10 5 257 2.8E-88 T 13-09-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 THL1_RS19760 6ce2a351327b1f1a7d0c0313d3e63205 472 PANTHER PTHR11699:SF212 1 472 3.7E-210 T 13-09-2016 THL1_RS19760 6ce2a351327b1f1a7d0c0313d3e63205 472 Gene3D G3DSA:3.40.309.10 258 445 1.8E-59 T 13-09-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 THL1_RS19760 6ce2a351327b1f1a7d0c0313d3e63205 472 Pfam PF00171 Aldehyde dehydrogenase family 13 470 3.6E-160 T 13-09-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 THL1_RS19760 6ce2a351327b1f1a7d0c0313d3e63205 472 PANTHER PTHR11699 1 472 3.7E-210 T 13-09-2016 THL1_RS19760 6ce2a351327b1f1a7d0c0313d3e63205 472 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 13-09-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 THL1_RS19760 6ce2a351327b1f1a7d0c0313d3e63205 472 SUPERFAMILY SSF53720 4 470 2.88E-156 T 13-09-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 THL1_RS02875 91657104cf6071f1870119801a849db7 133 PANTHER PTHR32071:SF39 2 120 9.3E-25 T 13-09-2016 THL1_RS02875 91657104cf6071f1870119801a849db7 133 Gene3D G3DSA:3.40.50.2300 1 121 1.5E-28 T 13-09-2016 THL1_RS02875 91657104cf6071f1870119801a849db7 133 Pfam PF00072 Response regulator receiver domain 4 114 2.8E-22 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02875 91657104cf6071f1870119801a849db7 133 SUPERFAMILY SSF52172 1 120 5.41E-26 T 13-09-2016 IPR011006 CheY-like superfamily THL1_RS02875 91657104cf6071f1870119801a849db7 133 SMART SM00448 2 114 2.2E-19 T 13-09-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 THL1_RS02875 91657104cf6071f1870119801a849db7 133 PANTHER PTHR32071 2 120 9.3E-25 T 13-09-2016 THL1_RS28390 49edf493246920392ee743586d318f3e 297 PANTHER PTHR36445:SF1 1 294 2.8E-81 T 13-09-2016 THL1_RS28390 49edf493246920392ee743586d318f3e 297 Pfam PF02649 Type I GTP cyclohydrolase folE2 6 288 3.2E-65 T 13-09-2016 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 THL1_RS28390 49edf493246920392ee743586d318f3e 297 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 6 293 31.703 T 13-09-2016 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 THL1_RS28390 49edf493246920392ee743586d318f3e 297 PANTHER PTHR36445 1 294 2.8E-81 T 13-09-2016 THL1_RS28390 49edf493246920392ee743586d318f3e 297 Gene3D G3DSA:3.10.270.10 5 158 1.4E-70 T 13-09-2016 THL1_RS28390 49edf493246920392ee743586d318f3e 297 Gene3D G3DSA:3.10.270.10 191 291 1.4E-70 T 13-09-2016 THL1_RS20935 10d49537721ad603fa9ab7c0c872f69f 301 PANTHER PTHR23024 56 300 1.9E-63 T 13-09-2016 THL1_RS20935 10d49537721ad603fa9ab7c0c872f69f 301 Pfam PF07859 alpha/beta hydrolase fold 74 276 3.7E-53 T 13-09-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 THL1_RS20935 10d49537721ad603fa9ab7c0c872f69f 301 SUPERFAMILY SSF53474 51 299 1.34E-57 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS20935 10d49537721ad603fa9ab7c0c872f69f 301 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 74 90 - T 13-09-2016 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 THL1_RS20935 10d49537721ad603fa9ab7c0c872f69f 301 Gene3D G3DSA:3.40.50.1820 20 299 5.6E-69 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS20935 10d49537721ad603fa9ab7c0c872f69f 301 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 142 154 - T 13-09-2016 IPR033140 Lipase, GDXG, putative serine active site THL1_RS08280 99b681bf6cab9b569d6ff33e20847fa6 739 Pfam PF04632 Fusaric acid resistance protein family 19 722 1.2E-198 T 13-09-2016 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 THL1_RS08280 99b681bf6cab9b569d6ff33e20847fa6 739 PANTHER PTHR30509 5 256 0.0 T 13-09-2016 THL1_RS08280 99b681bf6cab9b569d6ff33e20847fa6 739 PANTHER PTHR30509 348 688 0.0 T 13-09-2016 THL1_RS08280 99b681bf6cab9b569d6ff33e20847fa6 739 PANTHER PTHR30509:SF6 5 256 0.0 T 13-09-2016 THL1_RS08280 99b681bf6cab9b569d6ff33e20847fa6 739 PANTHER PTHR30509:SF6 348 688 0.0 T 13-09-2016 THL1_RS10605 86299a3361a7e8b6fdb657cd4584d833 715 SUPERFAMILY SSF48179 496 608 1.53E-29 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS10605 86299a3361a7e8b6fdb657cd4584d833 715 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 207 1.6E-37 T 13-09-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 THL1_RS10605 86299a3361a7e8b6fdb657cd4584d833 715 Hamap MF_01621 Fatty acid oxidation complex subunit alpha [fadB]. 1 715 51.912 T 13-09-2016 IPR012799 Fatty oxidation complex, alpha subunit FadB GO:0003857|GO:0004165|GO:0004300|GO:0008692|GO:0009062|GO:0036125|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35+5.3.3.8|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5137|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6837|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-7291|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS10605 86299a3361a7e8b6fdb657cd4584d833 715 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 318 495 8.0E-62 T 13-09-2016 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS10605 86299a3361a7e8b6fdb657cd4584d833 715 Gene3D G3DSA:3.40.50.720 311 498 1.5E-57 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10605 86299a3361a7e8b6fdb657cd4584d833 715 Gene3D G3DSA:1.10.1040.10 499 593 1.8E-22 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS10605 86299a3361a7e8b6fdb657cd4584d833 715 Gene3D G3DSA:1.10.1040.10 633 713 5.0E-15 T 13-09-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THL1_RS10605 86299a3361a7e8b6fdb657cd4584d833 715 SUPERFAMILY SSF48179 622 714 3.15E-23 T 13-09-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 THL1_RS10605 86299a3361a7e8b6fdb657cd4584d833 715 TIGRFAM TIGR02437 FadB: fatty oxidation complex, alpha subunit FadB 1 714 0.0 T 13-09-2016 IPR012799 Fatty oxidation complex, alpha subunit FadB GO:0003857|GO:0004165|GO:0004300|GO:0008692|GO:0009062|GO:0036125|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35+5.3.3.8|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5137|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6837|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-7291|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS10605 86299a3361a7e8b6fdb657cd4584d833 715 SUPERFAMILY SSF52096 2 308 3.2E-65 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS10605 86299a3361a7e8b6fdb657cd4584d833 715 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 494 519 - T 13-09-2016 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS10605 86299a3361a7e8b6fdb657cd4584d833 715 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 497 592 2.6E-27 T 13-09-2016 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7726|UniPathway: UPA00659 THL1_RS10605 86299a3361a7e8b6fdb657cd4584d833 715 Gene3D G3DSA:3.90.226.10 4 208 6.5E-56 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS10605 86299a3361a7e8b6fdb657cd4584d833 715 PANTHER PTHR23309:SF18 8 715 0.0 T 13-09-2016 THL1_RS10605 86299a3361a7e8b6fdb657cd4584d833 715 SUPERFAMILY SSF51735 317 496 1.43E-55 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS10605 86299a3361a7e8b6fdb657cd4584d833 715 PANTHER PTHR23309 8 715 0.0 T 13-09-2016 THL1_RS09000 2688cd91b49e2c5e1dd8fbdeed0507c6 106 PANTHER PTHR37827 11 105 1.6E-20 T 13-09-2016 THL1_RS09000 2688cd91b49e2c5e1dd8fbdeed0507c6 106 PANTHER PTHR37827:SF1 11 105 1.6E-20 T 13-09-2016 THL1_RS27435 ebbb0edcc21cfb707b991d85da0b99c4 377 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 28 355 3.5E-84 T 13-09-2016 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX THL1_RS27435 ebbb0edcc21cfb707b991d85da0b99c4 377 PANTHER PTHR38043 33 371 1.5E-55 T 13-09-2016 THL1_RS11520 d73428693a2d5b319f194033df00142b 283 Gene3D G3DSA:1.10.10.10 6 90 6.5E-25 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11520 d73428693a2d5b319f194033df00142b 283 PANTHER PTHR30579:SF6 1 283 1.0E-143 T 13-09-2016 THL1_RS11520 d73428693a2d5b319f194033df00142b 283 PANTHER PTHR30579 1 283 1.0E-143 T 13-09-2016 THL1_RS11520 d73428693a2d5b319f194033df00142b 283 SUPERFAMILY SSF46785 5 115 2.33E-23 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS11520 d73428693a2d5b319f194033df00142b 283 Pfam PF03466 LysR substrate binding domain 95 281 2.7E-22 T 13-09-2016 IPR005119 LysR, substrate-binding THL1_RS11520 d73428693a2d5b319f194033df00142b 283 Gene3D G3DSA:3.40.190.10 187 238 5.5E-5 T 13-09-2016 THL1_RS11520 d73428693a2d5b319f194033df00142b 283 SUPERFAMILY SSF53850 87 282 7.06E-25 T 13-09-2016 THL1_RS11520 d73428693a2d5b319f194033df00142b 283 Gene3D G3DSA:3.40.190.10 93 186 3.5E-17 T 13-09-2016 THL1_RS11520 d73428693a2d5b319f194033df00142b 283 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 9.8E-20 T 13-09-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THL1_RS19845 a071a5080bada8ac2eeb6c170527cf98 253 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 116 251 1.1E-41 T 13-09-2016 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal THL1_RS19845 a071a5080bada8ac2eeb6c170527cf98 253 PANTHER PTHR36307 37 251 2.8E-44 T 13-09-2016 THL1_RS19845 a071a5080bada8ac2eeb6c170527cf98 253 Pfam PF13144 Chaperone for flagella basal body P-ring formation 54 251 1.1E-61 T 13-09-2016 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal THL1_RS19845 a071a5080bada8ac2eeb6c170527cf98 253 SMART SM00858 128 190 1.7E-10 T 13-09-2016 IPR013974 SAF domain THL1_RS04710 3e6ad7372abda466b45ba3e38cbc837d 81 Pfam PF04325 Protein of unknown function (DUF465) 29 76 9.4E-13 T 13-09-2016 IPR007420 Protein of unknown function DUF465 THL1_RS24660 823a0def6c84a2674f2cc32979d4e842 102 Pfam PF12021 Protein of unknown function (DUF3509) 5 74 7.0E-8 T 13-09-2016 IPR021898 Protein of unknown function DUF3509 THL1_RS23985 343309cadf34e3a8ec6bc20367563f99 576 Pfam PF14559 Tetratricopeptide repeat 475 530 2.5E-7 T 13-09-2016 THL1_RS23985 343309cadf34e3a8ec6bc20367563f99 576 Pfam PF14559 Tetratricopeptide repeat 239 296 2.9E-9 T 13-09-2016 THL1_RS23985 343309cadf34e3a8ec6bc20367563f99 576 SMART SM00028 120 153 460.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS23985 343309cadf34e3a8ec6bc20367563f99 576 SMART SM00028 391 424 480.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS23985 343309cadf34e3a8ec6bc20367563f99 576 SMART SM00028 494 527 0.39 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS23985 343309cadf34e3a8ec6bc20367563f99 576 SMART SM00028 425 458 320.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS23985 343309cadf34e3a8ec6bc20367563f99 576 SMART SM00028 221 254 53.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS23985 343309cadf34e3a8ec6bc20367563f99 576 SMART SM00028 459 493 55.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS23985 343309cadf34e3a8ec6bc20367563f99 576 SUPERFAMILY SSF48452 116 347 5.38E-20 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS23985 343309cadf34e3a8ec6bc20367563f99 576 PANTHER PTHR23083 58 570 1.4E-75 T 13-09-2016 THL1_RS23985 343309cadf34e3a8ec6bc20367563f99 576 Gene3D G3DSA:1.25.40.10 355 560 5.2E-31 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS23985 343309cadf34e3a8ec6bc20367563f99 576 Gene3D G3DSA:1.25.40.10 115 345 7.2E-28 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS23985 343309cadf34e3a8ec6bc20367563f99 576 PANTHER PTHR23083:SF195 58 570 1.4E-75 T 13-09-2016 THL1_RS23985 343309cadf34e3a8ec6bc20367563f99 576 SUPERFAMILY SSF48452 392 561 6.96E-24 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS23240 961081c8cf5d6744142eb09be96ff0a7 284 SUPERFAMILY SSF52402 1 134 1.09E-27 T 13-09-2016 THL1_RS23240 961081c8cf5d6744142eb09be96ff0a7 284 PRINTS PR01438 Universal stress protein signature 1 18 9.1E-11 T 13-09-2016 IPR006015 Universal stress protein A THL1_RS23240 961081c8cf5d6744142eb09be96ff0a7 284 PRINTS PR01438 Universal stress protein signature 240 252 9.1E-11 T 13-09-2016 IPR006015 Universal stress protein A THL1_RS23240 961081c8cf5d6744142eb09be96ff0a7 284 PRINTS PR01438 Universal stress protein signature 258 280 9.1E-11 T 13-09-2016 IPR006015 Universal stress protein A THL1_RS23240 961081c8cf5d6744142eb09be96ff0a7 284 SUPERFAMILY SSF52402 141 281 2.26E-18 T 13-09-2016 THL1_RS23240 961081c8cf5d6744142eb09be96ff0a7 284 Gene3D G3DSA:3.40.50.620 2 128 1.6E-26 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS23240 961081c8cf5d6744142eb09be96ff0a7 284 PANTHER PTHR31964 224 284 5.8E-18 T 13-09-2016 THL1_RS23240 961081c8cf5d6744142eb09be96ff0a7 284 PANTHER PTHR31964 5 79 5.8E-18 T 13-09-2016 THL1_RS23240 961081c8cf5d6744142eb09be96ff0a7 284 Gene3D G3DSA:3.40.50.620 129 280 6.0E-21 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS23240 961081c8cf5d6744142eb09be96ff0a7 284 Pfam PF00582 Universal stress protein family 143 280 3.2E-13 T 13-09-2016 IPR006016 UspA GO:0006950 THL1_RS23240 961081c8cf5d6744142eb09be96ff0a7 284 Pfam PF00582 Universal stress protein family 2 131 1.4E-22 T 13-09-2016 IPR006016 UspA GO:0006950 THL1_RS06770 c803b48d9c009f1141994cea873bc13c 191 Gene3D G3DSA:3.40.50.150 19 190 4.2E-19 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS06770 c803b48d9c009f1141994cea873bc13c 191 Pfam PF13649 Methyltransferase domain 34 126 7.8E-12 T 13-09-2016 THL1_RS06770 c803b48d9c009f1141994cea873bc13c 191 SUPERFAMILY SSF53335 15 190 3.68E-22 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS23375 b4be3e257e6b8a2ba2709f8aa1c462f4 364 Gene3D G3DSA:2.130.10.10 61 348 1.1E-15 T 13-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THL1_RS23375 b4be3e257e6b8a2ba2709f8aa1c462f4 364 PIRSF PIRSF028101 1 364 1.8E-149 T 13-09-2016 IPR008311 Uncharacterised conserved protein UCP028101 THL1_RS23375 b4be3e257e6b8a2ba2709f8aa1c462f4 364 SUPERFAMILY SSF50969 53 348 9.42E-22 T 13-09-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like THL1_RS23375 b4be3e257e6b8a2ba2709f8aa1c462f4 364 Pfam PF07433 Protein of unknown function (DUF1513) 60 363 6.9E-112 T 13-09-2016 IPR008311 Uncharacterised conserved protein UCP028101 THL1_RS04240 431d3bdcc4c7c222b569425cd0570028 336 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 40 327 1.0E-120 T 13-09-2016 IPR011757 Lytic transglycosylase MltB THL1_RS04240 431d3bdcc4c7c222b569425cd0570028 336 Pfam PF13406 Transglycosylase SLT domain 36 327 4.1E-104 T 13-09-2016 IPR031304 Transglycosylase SLT domain 2 THL1_RS04240 431d3bdcc4c7c222b569425cd0570028 336 SUPERFAMILY SSF53955 23 329 2.81E-96 T 13-09-2016 IPR023346 Lysozyme-like domain THL1_RS04240 431d3bdcc4c7c222b569425cd0570028 336 Gene3D G3DSA:1.10.530.10 217 330 1.6E-57 T 13-09-2016 THL1_RS04240 431d3bdcc4c7c222b569425cd0570028 336 Gene3D G3DSA:1.10.530.10 79 135 1.6E-57 T 13-09-2016 THL1_RS04240 431d3bdcc4c7c222b569425cd0570028 336 PANTHER PTHR30163:SF0 3 336 2.1E-164 T 13-09-2016 THL1_RS04240 431d3bdcc4c7c222b569425cd0570028 336 PANTHER PTHR30163 3 336 2.1E-164 T 13-09-2016 IPR011757 Lytic transglycosylase MltB THL1_RS22310 a5a0853bf94a8caca161795ec2a11746 263 PANTHER PTHR11102 22 215 3.6E-40 T 13-09-2016 THL1_RS22310 a5a0853bf94a8caca161795ec2a11746 263 Gene3D G3DSA:1.25.40.10 25 258 2.2E-43 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS22310 a5a0853bf94a8caca161795ec2a11746 263 Pfam PF08238 Sel1 repeat 41 75 4.4E-7 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS22310 a5a0853bf94a8caca161795ec2a11746 263 Pfam PF08238 Sel1 repeat 77 110 2.2 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS22310 a5a0853bf94a8caca161795ec2a11746 263 Pfam PF08238 Sel1 repeat 200 215 25.0 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS22310 a5a0853bf94a8caca161795ec2a11746 263 Pfam PF08238 Sel1 repeat 148 183 4.0E-4 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS22310 a5a0853bf94a8caca161795ec2a11746 263 Pfam PF08238 Sel1 repeat 237 250 32.0 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS22310 a5a0853bf94a8caca161795ec2a11746 263 Pfam PF08238 Sel1 repeat 114 147 4.4E-7 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS22310 a5a0853bf94a8caca161795ec2a11746 263 SUPERFAMILY SSF81901 22 218 1.57E-40 T 13-09-2016 THL1_RS22310 a5a0853bf94a8caca161795ec2a11746 263 SMART SM00671 114 147 4.2E-4 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS22310 a5a0853bf94a8caca161795ec2a11746 263 SMART SM00671 76 111 0.0019 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS22310 a5a0853bf94a8caca161795ec2a11746 263 SMART SM00671 40 75 1.2E-7 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS22310 a5a0853bf94a8caca161795ec2a11746 263 SMART SM00671 148 183 1.0E-4 T 13-09-2016 IPR006597 Sel1-like repeat THL1_RS08850 e0dd40ea93755dfb62ae1ff04f65df31 171 PANTHER PTHR36180 18 163 1.9E-17 T 13-09-2016 THL1_RS08850 e0dd40ea93755dfb62ae1ff04f65df31 171 Pfam PF02498 BRO family, N-terminal domain 32 118 1.5E-8 T 13-09-2016 IPR003497 BRO N-terminal domain THL1_RS08850 e0dd40ea93755dfb62ae1ff04f65df31 171 SMART SM01040 31 118 5.1E-14 T 13-09-2016 IPR003497 BRO N-terminal domain THL1_RS08850 e0dd40ea93755dfb62ae1ff04f65df31 171 PANTHER PTHR36180:SF2 18 163 1.9E-17 T 13-09-2016 THL1_RS23715 b046b0538574d59e7ad4c408915ef7f1 313 PANTHER PTHR10992:SF818 40 313 1.7E-73 T 13-09-2016 THL1_RS23715 b046b0538574d59e7ad4c408915ef7f1 313 Pfam PF00561 alpha/beta hydrolase fold 61 297 1.1E-22 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS23715 b046b0538574d59e7ad4c408915ef7f1 313 PANTHER PTHR10992 40 313 1.7E-73 T 13-09-2016 THL1_RS23715 b046b0538574d59e7ad4c408915ef7f1 313 Gene3D G3DSA:3.40.50.1820 39 311 4.9E-68 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS23715 b046b0538574d59e7ad4c408915ef7f1 313 SUPERFAMILY SSF53474 40 311 2.68E-65 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS23715 b046b0538574d59e7ad4c408915ef7f1 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 131 144 2.5E-15 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS23715 b046b0538574d59e7ad4c408915ef7f1 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 257 271 2.5E-15 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS23715 b046b0538574d59e7ad4c408915ef7f1 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 86 101 2.5E-15 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS23715 b046b0538574d59e7ad4c408915ef7f1 313 PRINTS PR00111 Alpha/beta hydrolase fold signature 145 158 2.5E-15 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS13760 fe20691c27bdb2391caed1990b811e7b 289 Pfam PF13557 Putative MetA-pathway of phenol degradation 55 285 2.7E-29 T 13-09-2016 IPR025737 MetA-pathway of phenol degradation, putative THL1_RS24275 4a1d33ce496d9729ea1b16f6d0450e1f 147 SUPERFAMILY SSF57716 107 144 2.85E-10 T 13-09-2016 THL1_RS24275 4a1d33ce496d9729ea1b16f6d0450e1f 147 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 106 139 1.1E-11 T 13-09-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 THL1_RS24275 4a1d33ce496d9729ea1b16f6d0450e1f 147 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 24 146 30.87 T 13-09-2016 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 THL1_RS24275 4a1d33ce496d9729ea1b16f6d0450e1f 147 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 28 136 9.4E-52 T 13-09-2016 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 THL1_RS24275 4a1d33ce496d9729ea1b16f6d0450e1f 147 SUPERFAMILY SSF109635 11 106 3.4E-34 T 13-09-2016 THL1_RS24275 4a1d33ce496d9729ea1b16f6d0450e1f 147 PRINTS PR00618 DksA/TraR zinc finger signature 122 134 7.6E-5 T 13-09-2016 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria THL1_RS24275 4a1d33ce496d9729ea1b16f6d0450e1f 147 PRINTS PR00618 DksA/TraR zinc finger signature 110 121 7.6E-5 T 13-09-2016 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria THL1_RS24275 4a1d33ce496d9729ea1b16f6d0450e1f 147 PANTHER PTHR33823 4 144 2.6E-66 T 13-09-2016 THL1_RS24275 4a1d33ce496d9729ea1b16f6d0450e1f 147 PANTHER PTHR33823:SF2 4 144 2.6E-66 T 13-09-2016 THL1_RS24275 4a1d33ce496d9729ea1b16f6d0450e1f 147 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 110 134 - T 13-09-2016 IPR020458 Zinc finger, DksA/TraR C4-type conserved site THL1_RS09830 e3f674a102df0d672b9ccce79d7da93f 466 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 329 453 6.0E-9 T 13-09-2016 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain THL1_RS09830 e3f674a102df0d672b9ccce79d7da93f 466 Pfam PF01943 Polysaccharide biosynthesis protein 14 272 2.1E-22 T 13-09-2016 IPR002797 Polysaccharide biosynthesis protein GO:0016020 THL1_RS09830 e3f674a102df0d672b9ccce79d7da93f 466 PANTHER PTHR30250 3 424 3.2E-38 T 13-09-2016 THL1_RS09830 e3f674a102df0d672b9ccce79d7da93f 466 PANTHER PTHR30250:SF8 3 424 3.2E-38 T 13-09-2016 THL1_RS11615 4e7712a52ed04fa8b62b61f95b32b1cd 160 PANTHER PTHR21021 14 157 4.8E-55 T 13-09-2016 THL1_RS11615 4e7712a52ed04fa8b62b61f95b32b1cd 160 Pfam PF13185 GAF domain 38 152 9.4E-14 T 13-09-2016 IPR003018 GAF domain GO:0005515 THL1_RS11615 4e7712a52ed04fa8b62b61f95b32b1cd 160 SUPERFAMILY SSF55781 19 153 4.58E-41 T 13-09-2016 IPR029016 GAF domain-like THL1_RS11615 4e7712a52ed04fa8b62b61f95b32b1cd 160 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 97 114 - T 13-09-2016 IPR000614 Free Met sulfoxide reductase conserved site THL1_RS11615 4e7712a52ed04fa8b62b61f95b32b1cd 160 Gene3D G3DSA:3.30.450.40 17 152 1.1E-49 T 13-09-2016 IPR029016 GAF domain-like THL1_RS16530 78846d06668f2ca709a0824ff97e5ac1 570 PANTHER PTHR36577:SF1 1 569 8.0E-254 T 13-09-2016 THL1_RS16530 78846d06668f2ca709a0824ff97e5ac1 570 PIRSF PIRSF036630 1 570 2.5E-249 T 13-09-2016 IPR012047 Uncharacterised conserved protein UCP036630 THL1_RS16530 78846d06668f2ca709a0824ff97e5ac1 570 Gene3D G3DSA:3.30.499.10 454 520 2.6E-4 T 13-09-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 THL1_RS16530 78846d06668f2ca709a0824ff97e5ac1 570 SUPERFAMILY SSF52016 1 103 3.06E-33 T 13-09-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel THL1_RS16530 78846d06668f2ca709a0824ff97e5ac1 570 PANTHER PTHR36577 1 569 8.0E-254 T 13-09-2016 THL1_RS16530 78846d06668f2ca709a0824ff97e5ac1 570 Pfam PF04412 Protein of unknown function (DUF521) 152 554 4.1E-149 T 13-09-2016 IPR007506 Domain of unknown function DUF521 THL1_RS16530 78846d06668f2ca709a0824ff97e5ac1 570 Gene3D G3DSA:3.50.30.10 1 123 4.4E-40 T 13-09-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THL1_RS16530 78846d06668f2ca709a0824ff97e5ac1 570 Pfam PF01989 Protein of unknown function DUF126 16 92 3.4E-31 T 13-09-2016 IPR002840 Domain of unknown function DUF126 THL1_RS19870 60ca083a5e68d6d5d66ced213c2a9bd6 439 Gene3D G3DSA:1.20.1250.20 196 375 1.3E-23 T 13-09-2016 THL1_RS19870 60ca083a5e68d6d5d66ced213c2a9bd6 439 PANTHER PTHR23521 2 418 1.0E-189 T 13-09-2016 THL1_RS19870 60ca083a5e68d6d5d66ced213c2a9bd6 439 Gene3D G3DSA:1.20.1250.20 6 178 5.7E-12 T 13-09-2016 THL1_RS19870 60ca083a5e68d6d5d66ced213c2a9bd6 439 SUPERFAMILY SSF103473 3 369 5.62E-44 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS19870 60ca083a5e68d6d5d66ced213c2a9bd6 439 Pfam PF07690 Major Facilitator Superfamily 12 295 6.0E-17 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS19870 60ca083a5e68d6d5d66ced213c2a9bd6 439 PANTHER PTHR23521:SF2 2 418 1.0E-189 T 13-09-2016 THL1_RS02045 5a5752850e8e3c4d08ab0e0871eb0884 267 SUPERFAMILY SSF69572 12 243 1.31E-37 T 13-09-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 THL1_RS02045 5a5752850e8e3c4d08ab0e0871eb0884 267 Pfam PF00899 ThiF family 14 225 1.0E-28 T 13-09-2016 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 THL1_RS02045 5a5752850e8e3c4d08ab0e0871eb0884 267 PANTHER PTHR10953 1 150 8.3E-27 T 13-09-2016 THL1_RS02045 5a5752850e8e3c4d08ab0e0871eb0884 267 PANTHER PTHR10953:SF145 1 150 8.3E-27 T 13-09-2016 THL1_RS02045 5a5752850e8e3c4d08ab0e0871eb0884 267 Gene3D G3DSA:3.40.50.720 220 256 3.2E-32 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS02045 5a5752850e8e3c4d08ab0e0871eb0884 267 Gene3D G3DSA:3.40.50.720 12 188 3.2E-32 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS08775 41089fe495a430ca9e46589b365bf6e1 254 Pfam PF12146 Serine aminopeptidase, S33 91 185 1.2E-6 T 13-09-2016 IPR022742 Serine aminopeptidase, S33 THL1_RS08775 41089fe495a430ca9e46589b365bf6e1 254 PANTHER PTHR12277 22 248 7.7E-33 T 13-09-2016 THL1_RS08775 41089fe495a430ca9e46589b365bf6e1 254 SUPERFAMILY SSF53474 41 250 6.83E-31 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS08775 41089fe495a430ca9e46589b365bf6e1 254 Gene3D G3DSA:3.40.50.1820 63 250 6.0E-28 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS04890 20a4db15583feb44b55ec30a49b1e827 178 TIGRFAM TIGR02523 type_IV_pilV: type IV pilus modification protein PilV 1 133 9.1E-18 T 13-09-2016 IPR013362 Pilus modification type IV, PilV THL1_RS04890 20a4db15583feb44b55ec30a49b1e827 178 Pfam PF13633 Prokaryotic N-terminal methylation site 2 23 2.7E-5 T 13-09-2016 IPR012902 Prokaryotic N-terminal methylation site THL1_RS15525 b6c5d5762c685120a33991b71249cfce 617 Pfam PF06980 Protein of unknown function (DUF1302) 41 617 1.8E-170 T 13-09-2016 IPR010727 Protein of unknown function DUF1302 THL1_RS18775 c201c36577c1d70eb175046d87a214d9 482 Pfam PF13372 Alginate export 30 477 5.4E-98 T 13-09-2016 IPR025388 Alginate export domain UniPathway: UPA00286 THL1_RS15350 b2c20655edd2058bc1fcf693816912f0 146 PANTHER PTHR30574 9 141 1.5E-25 T 13-09-2016 THL1_RS15350 b2c20655edd2058bc1fcf693816912f0 146 Pfam PF04143 Sulphur transport 9 132 1.0E-6 T 13-09-2016 IPR007272 Sulphur transport domain THL1_RS15350 b2c20655edd2058bc1fcf693816912f0 146 PANTHER PTHR30574:SF1 9 141 1.5E-25 T 13-09-2016 THL1_RS02630 565b176071c2245dbe19a2deaadde5f9 223 SUPERFAMILY SSF53448 1 219 1.42E-56 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS02630 565b176071c2245dbe19a2deaadde5f9 223 Pfam PF00483 Nucleotidyl transferase 2 117 5.3E-21 T 13-09-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 THL1_RS02630 565b176071c2245dbe19a2deaadde5f9 223 PANTHER PTHR22572 2 221 4.1E-49 T 13-09-2016 THL1_RS02630 565b176071c2245dbe19a2deaadde5f9 223 Gene3D G3DSA:3.90.550.10 1 220 1.5E-56 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS11535 843fff9de61f8287c5f95ce4a78bd999 401 Pfam PF06224 Winged helix DNA-binding domain 37 378 5.4E-79 T 13-09-2016 IPR009351 Protein of unknown function DUF1006 THL1_RS11535 843fff9de61f8287c5f95ce4a78bd999 401 PANTHER PTHR30528 2 395 6.5E-108 T 13-09-2016 THL1_RS12465 6e32725467581e6ee0c244d80bf168e1 222 PANTHER PTHR23291:SF37 12 222 1.0E-111 T 13-09-2016 THL1_RS12465 6e32725467581e6ee0c244d80bf168e1 222 ProSitePatterns PS01243 Bax inhibitor-1 family signature. 88 119 - T 13-09-2016 IPR006213 Bax inhibitor 1, conserved site GO:0016021|GO:0043066 THL1_RS12465 6e32725467581e6ee0c244d80bf168e1 222 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 20 214 4.2E-44 T 13-09-2016 THL1_RS12465 6e32725467581e6ee0c244d80bf168e1 222 PANTHER PTHR23291 12 222 1.0E-111 T 13-09-2016 IPR006214 Bax inhibitor 1-related THL1_RS19100 7617bc9aacb10bb2c2ac01f522daf38e 167 Pfam PF13673 Acetyltransferase (GNAT) domain 32 114 2.0E-5 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS19100 7617bc9aacb10bb2c2ac01f522daf38e 167 Gene3D G3DSA:3.40.630.30 8 113 2.7E-10 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS19100 7617bc9aacb10bb2c2ac01f522daf38e 167 SUPERFAMILY SSF55729 8 117 8.51E-12 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS18345 1592f752f56d28226296416f7cf27357 244 PANTHER PTHR11040 5 241 1.2E-22 T 13-09-2016 THL1_RS18345 1592f752f56d28226296416f7cf27357 244 PANTHER PTHR11040:SF33 5 241 1.2E-22 T 13-09-2016 THL1_RS25250 9be41a34b0af20164fc12b7ad9a40458 109 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 9 98 1.7E-13 T 13-09-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THL1_RS25250 9be41a34b0af20164fc12b7ad9a40458 109 PANTHER PTHR33755 3 108 8.9E-13 T 13-09-2016 THL1_RS03595 1c41765f78b2cedff720507a88ebdbc4 130 Gene3D G3DSA:3.30.1370.30 2 71 1.5E-27 T 13-09-2016 THL1_RS03595 1c41765f78b2cedff720507a88ebdbc4 130 PANTHER PTHR11758 1 130 1.3E-60 T 13-09-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 THL1_RS03595 1c41765f78b2cedff720507a88ebdbc4 130 Gene3D G3DSA:3.30.1490.10 74 130 2.5E-27 T 13-09-2016 THL1_RS03595 1c41765f78b2cedff720507a88ebdbc4 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 13-09-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 THL1_RS03595 1c41765f78b2cedff720507a88ebdbc4 130 Pfam PF00410 Ribosomal protein S8 5 130 1.4E-48 T 13-09-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 THL1_RS03595 1c41765f78b2cedff720507a88ebdbc4 130 SUPERFAMILY SSF56047 2 130 8.63E-47 T 13-09-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 THL1_RS03595 1c41765f78b2cedff720507a88ebdbc4 130 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 130 31.705 T 13-09-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 THL1_RS21120 ab62670671c00358bd692e193a63ca19 108 Pfam PF03869 Arc-like DNA binding domain 11 59 1.8E-25 T 13-09-2016 IPR005569 Arc-like DNA binding domain GO:0003677 THL1_RS21120 ab62670671c00358bd692e193a63ca19 108 SUPERFAMILY SSF47598 12 57 1.25E-13 T 13-09-2016 IPR010985 Ribbon-helix-helix GO:0006355 THL1_RS21120 ab62670671c00358bd692e193a63ca19 108 Gene3D G3DSA:1.10.1220.10 11 66 4.9E-21 T 13-09-2016 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THL1_RS08765 f94b2fb64d3de758b6c7753546d9d734 196 Pfam PF02525 Flavodoxin-like fold 2 188 6.5E-35 T 13-09-2016 IPR003680 Flavodoxin-like fold THL1_RS08765 f94b2fb64d3de758b6c7753546d9d734 196 SUPERFAMILY SSF52218 1 193 4.82E-41 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS08765 f94b2fb64d3de758b6c7753546d9d734 196 PANTHER PTHR10204:SF36 1 192 1.4E-123 T 13-09-2016 THL1_RS08765 f94b2fb64d3de758b6c7753546d9d734 196 Gene3D G3DSA:3.40.50.360 1 194 2.0E-44 T 13-09-2016 IPR029039 Flavoprotein-like domain THL1_RS08765 f94b2fb64d3de758b6c7753546d9d734 196 PANTHER PTHR10204 1 192 1.4E-123 T 13-09-2016 THL1_RS14145 dd8a90873ca2a0325d50b0098e5f8afa 176 SMART SM01321 9 133 1.5E-31 T 13-09-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THL1_RS14145 dd8a90873ca2a0325d50b0098e5f8afa 176 PANTHER PTHR36966:SF1 1 176 6.6E-29 T 13-09-2016 THL1_RS14145 dd8a90873ca2a0325d50b0098e5f8afa 176 Pfam PF01797 Transposase IS200 like 14 130 1.3E-9 T 13-09-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THL1_RS14145 dd8a90873ca2a0325d50b0098e5f8afa 176 SUPERFAMILY SSF143422 1 139 7.85E-32 T 13-09-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THL1_RS14145 dd8a90873ca2a0325d50b0098e5f8afa 176 Gene3D G3DSA:3.30.70.1290 13 137 6.2E-15 T 13-09-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THL1_RS14145 dd8a90873ca2a0325d50b0098e5f8afa 176 PANTHER PTHR36966 1 176 6.6E-29 T 13-09-2016 THL1_RS17525 3cd4a15d247c02ca14df18b037e795e8 478 PANTHER PTHR33408:SF2 1 475 6.1E-181 T 13-09-2016 THL1_RS17525 3cd4a15d247c02ca14df18b037e795e8 478 PANTHER PTHR33408 1 475 6.1E-181 T 13-09-2016 THL1_RS17525 3cd4a15d247c02ca14df18b037e795e8 478 Pfam PF05598 Transposase domain (DUF772) 56 124 7.7E-19 T 13-09-2016 IPR008490 Transposase InsH, N-terminal THL1_RS17525 3cd4a15d247c02ca14df18b037e795e8 478 Pfam PF01609 Transposase DDE domain 232 460 2.2E-15 T 13-09-2016 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THL1_RS06395 dd6686c37a1262f6e6abe489c7aeb2d6 443 Pfam PF01882 Protein of unknown function DUF58 199 284 1.4E-22 T 13-09-2016 IPR002881 Domain of unknown function DUF58 THL1_RS06395 dd6686c37a1262f6e6abe489c7aeb2d6 443 PANTHER PTHR33608 2 443 3.2E-156 T 13-09-2016 THL1_RS06395 dd6686c37a1262f6e6abe489c7aeb2d6 443 PANTHER PTHR33608:SF3 2 443 3.2E-156 T 13-09-2016 THL1_RS19425 4aa316a3672c567739c0f284e973da1d 58 PANTHER PTHR37531 1 56 2.7E-21 T 13-09-2016 THL1_RS19425 4aa316a3672c567739c0f284e973da1d 58 PANTHER PTHR37531:SF1 1 56 2.7E-21 T 13-09-2016 THL1_RS19425 4aa316a3672c567739c0f284e973da1d 58 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 10 55 2.1E-19 T 13-09-2016 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 THL1_RS19425 4aa316a3672c567739c0f284e973da1d 58 Pfam PF04995 Heme exporter protein D (CcmD) 13 56 2.1E-15 T 13-09-2016 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 THL1_RS04510 a411e1f4e7dfbb64f1b20bdf940484e9 308 PANTHER PTHR32322 1 306 3.9E-126 T 13-09-2016 THL1_RS04510 a411e1f4e7dfbb64f1b20bdf940484e9 308 Pfam PF00892 EamA-like transporter family 14 141 1.0E-15 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS04510 a411e1f4e7dfbb64f1b20bdf940484e9 308 Pfam PF00892 EamA-like transporter family 151 284 1.9E-16 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS04510 a411e1f4e7dfbb64f1b20bdf940484e9 308 SUPERFAMILY SSF103481 44 145 3.66E-11 T 13-09-2016 THL1_RS04510 a411e1f4e7dfbb64f1b20bdf940484e9 308 PANTHER PTHR32322:SF8 1 306 3.9E-126 T 13-09-2016 THL1_RS04510 a411e1f4e7dfbb64f1b20bdf940484e9 308 SUPERFAMILY SSF103481 191 291 1.02E-10 T 13-09-2016 THL1_RS12965 65f87a3302aa164cdce30574ae18c28b 409 SUPERFAMILY SSF103473 11 402 3.92E-31 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS12965 65f87a3302aa164cdce30574ae18c28b 409 PANTHER PTHR23547 1 400 1.4E-176 T 13-09-2016 THL1_RS12965 65f87a3302aa164cdce30574ae18c28b 409 PANTHER PTHR23547:SF1 1 400 1.4E-176 T 13-09-2016 THL1_RS12965 65f87a3302aa164cdce30574ae18c28b 409 Pfam PF07690 Major Facilitator Superfamily 22 342 6.4E-16 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS12965 65f87a3302aa164cdce30574ae18c28b 409 Gene3D G3DSA:1.20.1250.20 221 405 4.5E-13 T 13-09-2016 THL1_RS12965 65f87a3302aa164cdce30574ae18c28b 409 Gene3D G3DSA:1.20.1250.20 12 204 2.3E-14 T 13-09-2016 THL1_RS27850 59d7eb17764aacde013494a280002b87 196 Pfam PF13511 Domain of unknown function (DUF4124) 14 76 8.1E-6 T 13-09-2016 IPR025392 Domain of unknown function DUF4124 THL1_RS11030 1bbbbd9b865f3b7cf2f6f2fb2b9e48e8 267 Gene3D G3DSA:3.40.50.1820 3 256 7.8E-33 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS11030 1bbbbd9b865f3b7cf2f6f2fb2b9e48e8 267 SUPERFAMILY SSF53474 3 253 2.32E-31 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS11030 1bbbbd9b865f3b7cf2f6f2fb2b9e48e8 267 PANTHER PTHR10992 52 257 4.5E-17 T 13-09-2016 THL1_RS11030 1bbbbd9b865f3b7cf2f6f2fb2b9e48e8 267 Pfam PF12697 Alpha/beta hydrolase family 4 249 8.8E-13 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS03760 c518bccdc37456abefc5fb6acec6c283 61 Pfam PF09489 Probable cobalt transporter subunit (CbtB) 12 61 3.8E-23 T 13-09-2016 IPR012667 Cobalt transporter subunit CbtB, putative THL1_RS03760 c518bccdc37456abefc5fb6acec6c283 61 TIGRFAM TIGR02459 CbtB: cobalt transporter subunit CbtB (proposed) 5 61 2.2E-25 T 13-09-2016 IPR012667 Cobalt transporter subunit CbtB, putative THL1_RS13310 9b3743a1689c0c7a75b9c101d034e9cd 248 Pfam PF09836 Putative DNA-binding domain 11 93 7.3E-22 T 13-09-2016 IPR018640 Putative DNA-binding domain, bacteria THL1_RS04200 9abb03afa03bba0da3b184d325ba1655 281 Pfam PF04072 Leucine carboxyl methyltransferase 64 176 5.2E-14 T 13-09-2016 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- THL1_RS04200 9abb03afa03bba0da3b184d325ba1655 281 SUPERFAMILY SSF53335 64 264 1.9E-26 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS04200 9abb03afa03bba0da3b184d325ba1655 281 Gene3D G3DSA:3.40.50.150 67 206 2.0E-17 T 13-09-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THL1_RS24990 0be2f25d54902783a59ca5b11e8145a1 163 Pfam PF11356 Type II secretion system protein C 27 149 2.0E-14 T 13-09-2016 IPR024961 Type II secretion system protein C, N-terminal THL1_RS17680 f95742eef63c2b0c5dddbfe3fba3fcf1 222 Pfam PF11185 Protein of unknown function (DUF2971) 77 146 2.6E-8 T 13-09-2016 IPR021352 Protein of unknown function DUF2971 THL1_RS05380 f3b422c6550a90d2529b076800583ed3 189 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 10 185 4.6E-46 T 13-09-2016 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 THL1_RS05380 f3b422c6550a90d2529b076800583ed3 189 PANTHER PTHR37481 2 189 1.5E-51 T 13-09-2016 THL1_RS05380 f3b422c6550a90d2529b076800583ed3 189 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 14 187 2.8E-49 T 13-09-2016 IPR010664 Lipopolysaccharide assembly, LptC-related THL1_RS05380 f3b422c6550a90d2529b076800583ed3 189 PANTHER PTHR37481:SF1 2 189 1.5E-51 T 13-09-2016 THL1_RS05380 f3b422c6550a90d2529b076800583ed3 189 Hamap MF_01915 Lipopolysaccharide export system protein LptC [lptC]. 5 189 24.387 T 13-09-2016 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 THL1_RS27705 6975bd676ec6260afc6a7938bbe9ad4f 830 Pfam PF13954 PapC N-terminal domain 36 183 5.3E-42 T 13-09-2016 IPR025885 PapC, N-terminal domain GO:0005515 THL1_RS27705 6975bd676ec6260afc6a7938bbe9ad4f 830 PANTHER PTHR30451 1 830 0.0 T 13-09-2016 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 THL1_RS27705 6975bd676ec6260afc6a7938bbe9ad4f 830 Pfam PF00577 Outer membrane usher protein 199 742 3.6E-167 T 13-09-2016 IPR000015 Outer membrane usher protein GO:0005215|GO:0006810|GO:0016020 THL1_RS27705 6975bd676ec6260afc6a7938bbe9ad4f 830 Pfam PF13953 PapC C-terminal domain 752 813 1.2E-15 T 13-09-2016 IPR025949 PapC-like, C-terminal domain THL1_RS27705 6975bd676ec6260afc6a7938bbe9ad4f 830 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 310 320 - T 13-09-2016 IPR018030 Fimbrial membrane usher, conserved site THL1_RS27705 6975bd676ec6260afc6a7938bbe9ad4f 830 PANTHER PTHR30451:SF2 1 830 0.0 T 13-09-2016 THL1_RS27705 6975bd676ec6260afc6a7938bbe9ad4f 830 SUPERFAMILY SSF141729 58 175 1.7E-29 T 13-09-2016 THL1_RS06900 2a9a729165da6b6896421c23fdf6f5e9 249 PANTHER PTHR30269 1 249 1.5E-69 T 13-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 THL1_RS06900 2a9a729165da6b6896421c23fdf6f5e9 249 PANTHER PTHR30269:SF14 1 249 1.5E-69 T 13-09-2016 THL1_RS06900 2a9a729165da6b6896421c23fdf6f5e9 249 Pfam PF01925 Sulfite exporter TauE/SafE 9 242 2.5E-38 T 13-09-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 THL1_RS04990 0ee29e3853211d2e5d1db2f53ab900be 324 PANTHER PTHR33055 1 321 9.0E-62 T 13-09-2016 THL1_RS04990 0ee29e3853211d2e5d1db2f53ab900be 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 197 280 1.9E-21 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS04990 0ee29e3853211d2e5d1db2f53ab900be 324 Pfam PF01548 Transposase 5 153 1.0E-32 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS04990 0ee29e3853211d2e5d1db2f53ab900be 324 PANTHER PTHR33055:SF3 1 321 9.0E-62 T 13-09-2016 THL1_RS01615 ccffb917592d10733c8d71fbde7375f9 150 Pfam PF01322 Cytochrome C' 29 148 9.3E-31 T 13-09-2016 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 THL1_RS01615 ccffb917592d10733c8d71fbde7375f9 150 PIRSF PIRSF000027 6 150 7.2E-36 T 13-09-2016 IPR012127 Cytochrome c prime GO:0005506|GO:0009055|GO:0020037|GO:0042597 THL1_RS01615 ccffb917592d10733c8d71fbde7375f9 150 SUPERFAMILY SSF47175 22 149 1.77E-30 T 13-09-2016 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 THL1_RS01615 ccffb917592d10733c8d71fbde7375f9 150 Gene3D G3DSA:1.20.120.10 23 149 5.0E-32 T 13-09-2016 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 THL1_RS10000 8128ccf634be98982963332578161578 148 Gene3D G3DSA:2.60.40.790 17 140 2.9E-17 T 13-09-2016 IPR008978 HSP20-like chaperone THL1_RS10000 8128ccf634be98982963332578161578 148 SUPERFAMILY SSF49764 11 141 3.84E-20 T 13-09-2016 IPR008978 HSP20-like chaperone THL1_RS10000 8128ccf634be98982963332578161578 148 PANTHER PTHR11527 1 147 3.1E-80 T 13-09-2016 IPR031107 Small heat shock protein HSP20 THL1_RS10000 8128ccf634be98982963332578161578 148 Pfam PF00011 Hsp20/alpha crystallin family 44 140 3.7E-16 T 13-09-2016 IPR002068 Alpha crystallin/Hsp20 domain THL1_RS10000 8128ccf634be98982963332578161578 148 PANTHER PTHR11527:SF127 1 147 3.1E-80 T 13-09-2016 THL1_RS27210 cb3ebcd69b7482d9031e6506f3c6b4c9 102 Pfam PF09498 Protein of unknown function (DUF2388) 30 99 3.7E-34 T 13-09-2016 IPR012661 Conserved hypothetical protein CHP02448 THL1_RS27210 cb3ebcd69b7482d9031e6506f3c6b4c9 102 TIGRFAM TIGR02448 TIGR02448: conserverd hypothetical protein 1 99 2.6E-35 T 13-09-2016 IPR012661 Conserved hypothetical protein CHP02448 THL1_RS09070 7db37bd3e69364f2fc511d6d5242ed1b 122 Pfam PF04480 Protein of unknown function (DUF559) 3 105 1.5E-40 T 13-09-2016 IPR007569 Domain of unknown function DUF559 THL1_RS09070 7db37bd3e69364f2fc511d6d5242ed1b 122 PANTHER PTHR38590:SF1 6 116 2.1E-43 T 13-09-2016 THL1_RS09070 7db37bd3e69364f2fc511d6d5242ed1b 122 PANTHER PTHR38590 6 116 2.1E-43 T 13-09-2016 THL1_RS09070 7db37bd3e69364f2fc511d6d5242ed1b 122 SUPERFAMILY SSF52980 5 117 5.36E-21 T 13-09-2016 IPR011335 Restriction endonuclease type II-like THL1_RS26265 822d04e43e3ce0496621b97f489635a0 254 Gene3D G3DSA:3.40.50.300 3 252 2.2E-54 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS26265 822d04e43e3ce0496621b97f489635a0 254 PANTHER PTHR13696:SF66 4 253 4.4E-108 T 13-09-2016 THL1_RS26265 822d04e43e3ce0496621b97f489635a0 254 Pfam PF13614 AAA domain 5 181 2.2E-37 T 13-09-2016 IPR025669 AAA domain THL1_RS26265 822d04e43e3ce0496621b97f489635a0 254 PANTHER PTHR13696 4 253 4.4E-108 T 13-09-2016 THL1_RS26265 822d04e43e3ce0496621b97f489635a0 254 SUPERFAMILY SSF52540 1 253 1.73E-50 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS14075 a38eac7e699fe572296e17613706f760 211 SUPERFAMILY SSF52833 40 195 9.3E-28 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS14075 a38eac7e699fe572296e17613706f760 211 Gene3D G3DSA:3.40.30.10 21 195 5.9E-28 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS14075 a38eac7e699fe572296e17613706f760 211 PANTHER PTHR12151:SF10 39 150 2.1E-20 T 13-09-2016 THL1_RS14075 a38eac7e699fe572296e17613706f760 211 Pfam PF02630 SCO1/SenC 9 141 9.4E-13 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS14075 a38eac7e699fe572296e17613706f760 211 PANTHER PTHR12151 39 150 2.1E-20 T 13-09-2016 IPR003782 Copper chaperone SCO1/SenC THL1_RS19185 366ee3f3877bc0ce06502af5e030b454 370 Gene3D G3DSA:3.40.640.10 51 269 1.7E-68 T 13-09-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 THL1_RS19185 366ee3f3877bc0ce06502af5e030b454 370 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 11 365 3.7E-111 T 13-09-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 THL1_RS19185 366ee3f3877bc0ce06502af5e030b454 370 Pfam PF00155 Aminotransferase class I and II 39 358 3.9E-50 T 13-09-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THL1_RS19185 366ee3f3877bc0ce06502af5e030b454 370 PANTHER PTHR11751 24 369 1.5E-109 T 13-09-2016 THL1_RS19185 366ee3f3877bc0ce06502af5e030b454 370 SUPERFAMILY SSF53383 18 367 1.2E-82 T 13-09-2016 IPR015424 Pyridoxal phosphate-dependent transferase THL1_RS19185 366ee3f3877bc0ce06502af5e030b454 370 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 8 367 63.536 T 13-09-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 THL1_RS19185 366ee3f3877bc0ce06502af5e030b454 370 PANTHER PTHR11751:SF347 24 369 1.5E-109 T 13-09-2016 THL1_RS19185 366ee3f3877bc0ce06502af5e030b454 370 Gene3D G3DSA:3.90.1150.10 270 367 1.7E-16 T 13-09-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 THL1_RS19185 366ee3f3877bc0ce06502af5e030b454 370 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 227 236 - T 13-09-2016 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 THL1_RS16570 39d39d8e494ea4cbfa116a18346b2ab3 82 PANTHER PTHR30085:SF2 22 82 3.6E-14 T 13-09-2016 THL1_RS16570 39d39d8e494ea4cbfa116a18346b2ab3 82 PANTHER PTHR30085 22 82 3.6E-14 T 13-09-2016 THL1_RS18245 cfbf84ba0f5910685293a38ebf317106 181 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 172 39.657 T 13-09-2016 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.53+1.13.11.54|MetaCyc: PWY-4361|MetaCyc: PWY-5389|UniPathway: UPA00904 THL1_RS18245 cfbf84ba0f5910685293a38ebf317106 181 Gene3D G3DSA:2.60.120.10 4 179 1.3E-58 T 13-09-2016 IPR014710 RmlC-like jelly roll fold THL1_RS18245 cfbf84ba0f5910685293a38ebf317106 181 PANTHER PTHR23418 29 181 5.1E-36 T 13-09-2016 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|UniPathway: UPA00904 THL1_RS18245 cfbf84ba0f5910685293a38ebf317106 181 SUPERFAMILY SSF51182 3 178 4.08E-44 T 13-09-2016 IPR011051 RmlC-like cupin domain THL1_RS18245 cfbf84ba0f5910685293a38ebf317106 181 Pfam PF03079 ARD/ARD' family 6 165 7.9E-35 T 13-09-2016 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|UniPathway: UPA00904 THL1_RS02600 3ab1b65b0b3770d5948d6d86a3ecc623 126 Hamap MF_00791 Protein ApaG [apaG]. 1 126 33.907 T 13-09-2016 IPR023065 Uncharacterised protein family ApaG THL1_RS02600 3ab1b65b0b3770d5948d6d86a3ecc623 126 Gene3D G3DSA:2.60.40.1470 6 125 3.3E-47 T 13-09-2016 IPR007474 ApaG domain THL1_RS02600 3ab1b65b0b3770d5948d6d86a3ecc623 126 SUPERFAMILY SSF110069 7 126 8.5E-49 T 13-09-2016 IPR007474 ApaG domain THL1_RS02600 3ab1b65b0b3770d5948d6d86a3ecc623 126 PANTHER PTHR14289 10 123 1.1E-55 T 13-09-2016 THL1_RS02600 3ab1b65b0b3770d5948d6d86a3ecc623 126 Pfam PF04379 Protein of unknown function (DUF525) 18 103 1.5E-35 T 13-09-2016 IPR007474 ApaG domain THL1_RS10915 b4ace96cf0f8d226b6156e1b255a1117 129 SUPERFAMILY SSF161084 5 124 1.31E-27 T 13-09-2016 THL1_RS10915 b4ace96cf0f8d226b6156e1b255a1117 129 Gene3D G3DSA:1.20.120.550 6 125 2.3E-18 T 13-09-2016 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain THL1_RS10915 b4ace96cf0f8d226b6156e1b255a1117 129 PANTHER PTHR35371 1 129 1.8E-29 T 13-09-2016 THL1_RS10915 b4ace96cf0f8d226b6156e1b255a1117 129 Pfam PF01124 MAPEG family 4 126 3.9E-28 T 13-09-2016 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein THL1_RS10915 b4ace96cf0f8d226b6156e1b255a1117 129 PANTHER PTHR35371:SF1 1 129 1.8E-29 T 13-09-2016 THL1_RS00765 ffa8a49cb8952f441d5d9ad4ba0f4138 254 Pfam PF03818 Malonate/sodium symporter MadM subunit 4 61 1.0E-27 T 13-09-2016 IPR018402 Malonate/sodium symporter MadM subunit, N-terminal THL1_RS00765 ffa8a49cb8952f441d5d9ad4ba0f4138 254 TIGRFAM TIGR00808 malonate_madM: malonate transporter, MadM subunit 1 254 2.6E-140 T 13-09-2016 IPR004691 Malonate/sodium symporter MadM subunit GO:0044668 THL1_RS05570 f9d1525b016a9aeb3ac0dc7a1d3bcc4e 197 PANTHER PTHR30390:SF5 3 197 2.3E-121 T 13-09-2016 THL1_RS05570 f9d1525b016a9aeb3ac0dc7a1d3bcc4e 197 PANTHER PTHR30390 3 197 2.3E-121 T 13-09-2016 THL1_RS05570 f9d1525b016a9aeb3ac0dc7a1d3bcc4e 197 Pfam PF13580 SIS domain 11 146 3.1E-35 T 13-09-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 THL1_RS05570 f9d1525b016a9aeb3ac0dc7a1d3bcc4e 197 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 2 192 37.03 T 13-09-2016 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478|UniPathway: UPA00041 THL1_RS05570 f9d1525b016a9aeb3ac0dc7a1d3bcc4e 197 Gene3D G3DSA:3.40.50.10490 2 194 5.4E-59 T 13-09-2016 THL1_RS05570 f9d1525b016a9aeb3ac0dc7a1d3bcc4e 197 SUPERFAMILY SSF53697 2 193 4.25E-56 T 13-09-2016 THL1_RS23365 237506303bb93e129ffede2b3df414ab 476 PANTHER PTHR30600:SF4 32 112 1.0E-162 T 13-09-2016 THL1_RS23365 237506303bb93e129ffede2b3df414ab 476 PANTHER PTHR30600:SF4 188 236 1.0E-162 T 13-09-2016 THL1_RS23365 237506303bb93e129ffede2b3df414ab 476 Gene3D G3DSA:1.10.760.10 335 476 5.6E-18 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS23365 237506303bb93e129ffede2b3df414ab 476 PANTHER PTHR30600 261 476 1.0E-162 T 13-09-2016 THL1_RS23365 237506303bb93e129ffede2b3df414ab 476 PANTHER PTHR30600 32 112 1.0E-162 T 13-09-2016 THL1_RS23365 237506303bb93e129ffede2b3df414ab 476 PANTHER PTHR30600 188 236 1.0E-162 T 13-09-2016 THL1_RS23365 237506303bb93e129ffede2b3df414ab 476 Pfam PF06537 Di-haem oxidoreductase, putative peroxidase 37 476 2.9E-140 T 13-09-2016 IPR010538 Di-haem oxidoreductase, putative peroxidase THL1_RS23365 237506303bb93e129ffede2b3df414ab 476 PIRSF PIRSF028099 6 476 1.0E-186 T 13-09-2016 IPR010538 Di-haem oxidoreductase, putative peroxidase THL1_RS23365 237506303bb93e129ffede2b3df414ab 476 SUPERFAMILY SSF46626 333 476 3.1E-24 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS23365 237506303bb93e129ffede2b3df414ab 476 PANTHER PTHR30600:SF4 261 476 1.0E-162 T 13-09-2016 THL1_RS11735 ff2cf5de0a6cbcd25a6856d154477aa8 346 Hamap MF_00790 Lipase chaperone [lifO]. 1 337 21.527 T 13-09-2016 IPR004961 Lipase chaperone GO:0006457|GO:0016020|GO:0051082 THL1_RS11735 ff2cf5de0a6cbcd25a6856d154477aa8 346 Pfam PF03280 Proteobacterial lipase chaperone protein 139 329 2.6E-51 T 13-09-2016 IPR004961 Lipase chaperone GO:0006457|GO:0016020|GO:0051082 THL1_RS11735 ff2cf5de0a6cbcd25a6856d154477aa8 346 SUPERFAMILY SSF158855 67 334 6.8E-72 T 13-09-2016 THL1_RS27685 a9aa33f8559ca0aa28f6ff9b1d85a3ee 658 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 53 498 5.1E-161 T 13-09-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 THL1_RS27685 a9aa33f8559ca0aa28f6ff9b1d85a3ee 658 ProSitePatterns PS01303 BCCT family of transporters signature. 315 324 - T 13-09-2016 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 THL1_RS27685 a9aa33f8559ca0aa28f6ff9b1d85a3ee 658 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 15 498 3.8E-197 T 13-09-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 THL1_RS27685 a9aa33f8559ca0aa28f6ff9b1d85a3ee 658 PANTHER PTHR30047 8 658 9.6E-298 T 13-09-2016 THL1_RS27685 a9aa33f8559ca0aa28f6ff9b1d85a3ee 658 PANTHER PTHR30047:SF2 8 658 9.6E-298 T 13-09-2016 THL1_RS01390 fe4b23618117610510b1f4d2f4c14495 221 SUPERFAMILY SSF56529 14 220 1.01E-63 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS01390 fe4b23618117610510b1f4d2f4c14495 221 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 19 220 3.8E-52 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS01390 fe4b23618117610510b1f4d2f4c14495 221 Gene3D G3DSA:3.90.850.10 15 220 5.9E-69 T 13-09-2016 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 THL1_RS01390 fe4b23618117610510b1f4d2f4c14495 221 PANTHER PTHR11820 12 220 7.9E-74 T 13-09-2016 THL1_RS27150 60061ef983eed461de9e3c4364636cba 127 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 14 124 2.3E-25 T 13-09-2016 IPR003736 Phenylacetic acid degradation-related domain THL1_RS27150 60061ef983eed461de9e3c4364636cba 127 SUPERFAMILY SSF54637 10 126 2.23E-35 T 13-09-2016 IPR029069 HotDog domain THL1_RS27150 60061ef983eed461de9e3c4364636cba 127 Gene3D G3DSA:3.10.129.10 9 125 9.4E-39 T 13-09-2016 IPR029069 HotDog domain THL1_RS27150 60061ef983eed461de9e3c4364636cba 127 PANTHER PTHR12418:SF27 12 124 4.3E-36 T 13-09-2016 THL1_RS27150 60061ef983eed461de9e3c4364636cba 127 PANTHER PTHR12418 12 124 4.3E-36 T 13-09-2016 THL1_RS27150 60061ef983eed461de9e3c4364636cba 127 Pfam PF03061 Thioesterase superfamily 43 116 9.1E-20 T 13-09-2016 IPR006683 Thioesterase domain THL1_RS27120 1d0d176d3bcd0971be48ff892f6051e5 154 Gene3D G3DSA:2.40.70.10 8 134 1.3E-40 T 13-09-2016 IPR021109 Aspartic peptidase domain THL1_RS27120 1d0d176d3bcd0971be48ff892f6051e5 154 PANTHER PTHR38037 1 154 2.2E-57 T 13-09-2016 THL1_RS27120 1d0d176d3bcd0971be48ff892f6051e5 154 SUPERFAMILY SSF50630 9 143 1.13E-40 T 13-09-2016 IPR021109 Aspartic peptidase domain THL1_RS27120 1d0d176d3bcd0971be48ff892f6051e5 154 Pfam PF05618 Putative ATP-dependant zinc protease 9 146 1.4E-45 T 13-09-2016 THL1_RS22270 c908dc4171f3054d96444062ab328cf3 238 Pfam PF11306 Protein of unknown function (DUF3108) 16 219 1.0E-22 T 13-09-2016 IPR021457 Protein of unknown function DUF3108 THL1_RS12730 23676f50f2b01ea6d412f916053e215a 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 246 8.0E-58 T 13-09-2016 THL1_RS12730 23676f50f2b01ea6d412f916053e215a 252 SUPERFAMILY SSF51735 9 250 8.67E-80 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS12730 23676f50f2b01ea6d412f916053e215a 252 PANTHER PTHR24322 15 144 5.2E-45 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12730 23676f50f2b01ea6d412f916053e215a 252 PANTHER PTHR24322 160 191 5.2E-45 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12730 23676f50f2b01ea6d412f916053e215a 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 5.2E-6 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12730 23676f50f2b01ea6d412f916053e215a 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 5.2E-6 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12730 23676f50f2b01ea6d412f916053e215a 252 Gene3D G3DSA:3.40.50.720 5 249 8.6E-82 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS12730 23676f50f2b01ea6d412f916053e215a 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 3.4E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12730 23676f50f2b01ea6d412f916053e215a 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 3.4E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12730 23676f50f2b01ea6d412f916053e215a 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 3.4E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12730 23676f50f2b01ea6d412f916053e215a 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 3.4E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12730 23676f50f2b01ea6d412f916053e215a 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 3.4E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS12730 23676f50f2b01ea6d412f916053e215a 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 3.4E-37 T 13-09-2016 IPR002347 Short-chain dehydrogenase/reductase SDR THL1_RS02340 160f660ea9de5119b86966f74064b737 263 Gene3D G3DSA:1.10.3720.10 16 260 1.7E-57 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS02340 160f660ea9de5119b86966f74064b737 263 PANTHER PTHR30222:SF7 11 258 1.2E-104 T 13-09-2016 THL1_RS02340 160f660ea9de5119b86966f74064b737 263 SUPERFAMILY SSF161098 15 259 9.68E-56 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS02340 160f660ea9de5119b86966f74064b737 263 PANTHER PTHR30222 11 258 1.2E-104 T 13-09-2016 THL1_RS02340 160f660ea9de5119b86966f74064b737 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 257 1.8E-18 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS11530 c58b1896eeb8df038845631fd263742b 166 Pfam PF11695 Domain of unknown function (DUF3291) 7 143 4.0E-60 T 13-09-2016 IPR021708 Domain of unknown function DUF3291 THL1_RS11530 c58b1896eeb8df038845631fd263742b 166 SUPERFAMILY SSF54909 15 118 1.48E-16 T 13-09-2016 IPR011008 Dimeric alpha-beta barrel THL1_RS19850 c8e6c235ff9f5cbf2e49f6f1faa89114 112 SUPERFAMILY SSF101498 38 109 1.96E-19 T 13-09-2016 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 THL1_RS19850 c8e6c235ff9f5cbf2e49f6f1faa89114 112 Pfam PF04316 Anti-sigma-28 factor, FlgM 54 107 3.1E-19 T 13-09-2016 IPR031316 Anti-sigma-28 factor FlgM, C-terminal THL1_RS19850 c8e6c235ff9f5cbf2e49f6f1faa89114 112 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 5 109 6.0E-26 T 13-09-2016 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 THL1_RS23475 8aa09142eab91c561219577bffb07263 107 Pfam PF11804 Protein of unknown function (DUF3325) 4 102 4.3E-24 T 13-09-2016 IPR021762 Protein of unknown function DUF3325 THL1_RS14265 54c38ac55aa4a9bc4c55e98d0bace992 250 PANTHER PTHR40279 1 249 1.1E-155 T 13-09-2016 THL1_RS14265 54c38ac55aa4a9bc4c55e98d0bace992 250 Hamap MF_00654 Pyrroloquinoline-quinone synthase [pqqC]. 1 250 143.035 T 13-09-2016 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420|UniPathway: UPA00539 THL1_RS14265 54c38ac55aa4a9bc4c55e98d0bace992 250 Gene3D G3DSA:1.20.910.10 3 248 6.4E-123 T 13-09-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 THL1_RS14265 54c38ac55aa4a9bc4c55e98d0bace992 250 TIGRFAM TIGR02111 PQQ_syn_pqqC: coenzyme PQQ biosynthesis protein C 6 241 5.9E-124 T 13-09-2016 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420|UniPathway: UPA00539 THL1_RS14265 54c38ac55aa4a9bc4c55e98d0bace992 250 PANTHER PTHR40279:SF2 1 249 1.1E-155 T 13-09-2016 THL1_RS14265 54c38ac55aa4a9bc4c55e98d0bace992 250 Pfam PF03070 TENA/THI-4/PQQC family 13 222 3.9E-64 T 13-09-2016 IPR004305 Thiaminase-2/PQQC THL1_RS14265 54c38ac55aa4a9bc4c55e98d0bace992 250 SUPERFAMILY SSF48613 1 248 9.64E-80 T 13-09-2016 IPR016084 Haem oxygenase-like, multi-helical Reactome: REACT_9431 THL1_RS12535 4dccf019aec75273f6fbf68b646fbfb5 140 SUPERFAMILY SSF54593 5 130 1.34E-27 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS12535 4dccf019aec75273f6fbf68b646fbfb5 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 124 6.6E-11 T 13-09-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain THL1_RS12535 4dccf019aec75273f6fbf68b646fbfb5 140 Gene3D G3DSA:3.10.180.10 2 128 8.0E-24 T 13-09-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THL1_RS04570 3fcd97d25a2e4c31744f70071c8b75cc 184 SUPERFAMILY SSF55729 3 173 3.61E-38 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS04570 3fcd97d25a2e4c31744f70071c8b75cc 184 PANTHER PTHR13256 2 184 3.3E-52 T 13-09-2016 THL1_RS04570 3fcd97d25a2e4c31744f70071c8b75cc 184 Pfam PF13302 Acetyltransferase (GNAT) domain 8 149 1.3E-31 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS04570 3fcd97d25a2e4c31744f70071c8b75cc 184 PANTHER PTHR13256:SF19 2 184 3.3E-52 T 13-09-2016 THL1_RS04570 3fcd97d25a2e4c31744f70071c8b75cc 184 Gene3D G3DSA:3.40.630.30 3 182 1.7E-48 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS16395 d750f8d05920fe4a8f3730bf20cb5bc6 498 Pfam PF11855 Protein of unknown function (DUF3375) 15 485 2.5E-97 T 13-09-2016 IPR021804 Protein of unknown function DUF3375 THL1_RS08685 7a6245d6295f493e3b2dec8626aec690 430 SUPERFAMILY SSF48537 162 327 6.05E-21 T 13-09-2016 IPR008947 Phospholipase C/P1 nuclease domain GO:0016788 THL1_RS08685 7a6245d6295f493e3b2dec8626aec690 430 Gene3D G3DSA:1.10.575.10 162 327 1.9E-29 T 13-09-2016 IPR008947 Phospholipase C/P1 nuclease domain GO:0016788 THL1_RS15905 72a574f71746c8156bb52537133afa10 472 PANTHER PTHR41983 1 460 0.0 T 13-09-2016 THL1_RS15905 72a574f71746c8156bb52537133afa10 472 Pfam PF02667 Short chain fatty acid transporter 12 456 6.4E-86 T 13-09-2016 IPR006160 Short chain fatty acid transporter AtoE THL1_RS15905 72a574f71746c8156bb52537133afa10 472 PANTHER PTHR41983:SF1 1 460 0.0 T 13-09-2016 THL1_RS08810 913b751ee5551261083fb558ad7acd7c 283 PANTHER PTHR31157:SF1 24 281 2.8E-62 T 13-09-2016 THL1_RS08810 913b751ee5551261083fb558ad7acd7c 283 SUPERFAMILY SSF55797 146 281 2.49E-24 T 13-09-2016 IPR014044 CAP domain THL1_RS08810 913b751ee5551261083fb558ad7acd7c 283 Pfam PF00188 Cysteine-rich secretory protein family 153 280 1.0E-18 T 13-09-2016 IPR014044 CAP domain THL1_RS08810 913b751ee5551261083fb558ad7acd7c 283 Gene3D G3DSA:3.40.33.10 146 281 5.3E-15 T 13-09-2016 IPR014044 CAP domain THL1_RS08810 913b751ee5551261083fb558ad7acd7c 283 PANTHER PTHR31157 24 281 2.8E-62 T 13-09-2016 THL1_RS03380 9be2a0e8f7be59813f8cc3fc54172ab1 363 SUPERFAMILY SSF53067 63 108 1.01E-27 T 13-09-2016 THL1_RS03380 9be2a0e8f7be59813f8cc3fc54172ab1 363 SUPERFAMILY SSF53067 138 336 1.01E-27 T 13-09-2016 THL1_RS03380 9be2a0e8f7be59813f8cc3fc54172ab1 363 SUPERFAMILY SSF53067 3 36 1.01E-27 T 13-09-2016 THL1_RS03380 9be2a0e8f7be59813f8cc3fc54172ab1 363 Pfam PF03702 Uncharacterised protein family (UPF0075) 3 363 5.7E-154 T 13-09-2016 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17|UniPathway: UPA00343|UniPathway: UPA00544 THL1_RS03380 9be2a0e8f7be59813f8cc3fc54172ab1 363 PANTHER PTHR30605 1 362 2.1E-154 T 13-09-2016 THL1_RS03380 9be2a0e8f7be59813f8cc3fc54172ab1 363 Gene3D G3DSA:3.30.420.40 2 191 2.9E-68 T 13-09-2016 THL1_RS03380 9be2a0e8f7be59813f8cc3fc54172ab1 363 PANTHER PTHR30605:SF0 1 362 2.1E-154 T 13-09-2016 THL1_RS03380 9be2a0e8f7be59813f8cc3fc54172ab1 363 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 2 363 40.17 T 13-09-2016 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17|UniPathway: UPA00343|UniPathway: UPA00544 THL1_RS04085 288f543bf643bb929acdd15348b295d7 277 PIRSF PIRSF018982 1 260 1.7E-107 T 13-09-2016 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7|UniPathway: UPA00560 THL1_RS04085 288f543bf643bb929acdd15348b295d7 277 Hamap MF_00601 Ethanolamine ammonia-lyase light chain [eutC]. 5 250 38.959 T 13-09-2016 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7|UniPathway: UPA00560 THL1_RS04085 288f543bf643bb929acdd15348b295d7 277 Pfam PF05985 Ethanolamine ammonia-lyase light chain (EutC) 13 250 2.4E-95 T 13-09-2016 IPR009246 Ethanolamine ammonia-lyase light chain GO:0006520|GO:0008851 KEGG: 00564+4.3.1.7|UniPathway: UPA00560 THL1_RS04085 288f543bf643bb929acdd15348b295d7 277 PANTHER PTHR39330 12 267 2.8E-119 T 13-09-2016 THL1_RS25525 13da29329b235aa40deae6c618506e9b 600 TIGRFAM TIGR02713 allophanate_hyd: allophanate hydrolase 40 595 3.7E-247 T 13-09-2016 IPR014085 Allophanate hydrolase KEGG: 00220+3.5.1.54|KEGG: 00791+3.5.1.54|MetaCyc: PWY-5169|MetaCyc: PWY-5703 THL1_RS25525 13da29329b235aa40deae6c618506e9b 600 PANTHER PTHR11895 9 457 1.3E-162 T 13-09-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS25525 13da29329b235aa40deae6c618506e9b 600 Pfam PF01425 Amidase 53 439 5.5E-90 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS25525 13da29329b235aa40deae6c618506e9b 600 SUPERFAMILY SSF75304 14 448 2.88E-112 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS25525 13da29329b235aa40deae6c618506e9b 600 Gene3D G3DSA:3.90.1300.10 15 451 4.9E-110 T 13-09-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THL1_RS25525 13da29329b235aa40deae6c618506e9b 600 PANTHER PTHR11895:SF24 9 457 1.3E-162 T 13-09-2016 THL1_RS24075 cb29ea11a7bd489b407226035b0bab40 150 PANTHER PTHR23091:SF247 1 148 5.2E-36 T 13-09-2016 THL1_RS24075 cb29ea11a7bd489b407226035b0bab40 150 SUPERFAMILY SSF55729 5 148 4.22E-34 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS24075 cb29ea11a7bd489b407226035b0bab40 150 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 14 144 7.6E-45 T 13-09-2016 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 THL1_RS24075 cb29ea11a7bd489b407226035b0bab40 150 PANTHER PTHR23091 1 148 5.2E-36 T 13-09-2016 THL1_RS24075 cb29ea11a7bd489b407226035b0bab40 150 Pfam PF13673 Acetyltransferase (GNAT) domain 40 128 7.1E-14 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS24075 cb29ea11a7bd489b407226035b0bab40 150 Gene3D G3DSA:3.40.630.30 5 148 1.3E-34 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS27330 8923d8ee0dc69a665b8f0f9afdf26b60 744 Pfam PF13090 Polyphosphate kinase C-terminal domain 387 732 4.4E-152 T 13-09-2016 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 THL1_RS27330 8923d8ee0dc69a665b8f0f9afdf26b60 744 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 61 734 1.5E-284 T 13-09-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 THL1_RS27330 8923d8ee0dc69a665b8f0f9afdf26b60 744 Pfam PF13089 Polyphosphate kinase N-terminal domain 61 166 1.4E-34 T 13-09-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 THL1_RS27330 8923d8ee0dc69a665b8f0f9afdf26b60 744 Gene3D G3DSA:3.30.1840.10 164 356 1.3E-68 T 13-09-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 THL1_RS27330 8923d8ee0dc69a665b8f0f9afdf26b60 744 Gene3D G3DSA:3.30.870.10 556 737 3.3E-74 T 13-09-2016 THL1_RS27330 8923d8ee0dc69a665b8f0f9afdf26b60 744 SUPERFAMILY SSF140356 58 162 9.55E-37 T 13-09-2016 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 THL1_RS27330 8923d8ee0dc69a665b8f0f9afdf26b60 744 Pfam PF02503 Polyphosphate kinase middle domain 177 377 1.6E-62 T 13-09-2016 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 THL1_RS27330 8923d8ee0dc69a665b8f0f9afdf26b60 744 SUPERFAMILY SSF143724 166 366 4.9E-62 T 13-09-2016 THL1_RS27330 8923d8ee0dc69a665b8f0f9afdf26b60 744 PIRSF PIRSF015589 34 740 4.1E-285 T 13-09-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 THL1_RS27330 8923d8ee0dc69a665b8f0f9afdf26b60 744 PANTHER PTHR30218 25 744 0.0 T 13-09-2016 THL1_RS27330 8923d8ee0dc69a665b8f0f9afdf26b60 744 Gene3D G3DSA:3.30.870.10 372 555 3.4E-73 T 13-09-2016 THL1_RS27330 8923d8ee0dc69a665b8f0f9afdf26b60 744 PANTHER PTHR30218:SF0 25 744 0.0 T 13-09-2016 THL1_RS27330 8923d8ee0dc69a665b8f0f9afdf26b60 744 Hamap MF_00347 Polyphosphate kinase [ppk]. 58 737 34.378 T 13-09-2016 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 THL1_RS27330 8923d8ee0dc69a665b8f0f9afdf26b60 744 SUPERFAMILY SSF56024 556 737 1.03E-71 T 13-09-2016 THL1_RS27330 8923d8ee0dc69a665b8f0f9afdf26b60 744 SUPERFAMILY SSF56024 371 552 1.49E-55 T 13-09-2016 THL1_RS16090 603f4901bbf584d5b456f4cbef37ff1a 279 Pfam PF05929 Phage capsid scaffolding protein (GPO) serine peptidase 6 279 5.9E-101 T 13-09-2016 IPR009228 Capsid scaffolding protein GpO GO:0019069 THL1_RS20585 f78ce027c2a2121714760ff323b1a2ae 150 Gene3D G3DSA:3.10.450.50 21 147 5.6E-20 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS20585 f78ce027c2a2121714760ff323b1a2ae 150 Pfam PF12680 SnoaL-like domain 27 132 6.0E-8 T 13-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain THL1_RS20585 f78ce027c2a2121714760ff323b1a2ae 150 SUPERFAMILY SSF54427 20 143 1.27E-19 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS18485 5c585ae97739ee657c0309aead4c1be6 200 Pfam PF16105 Domain of unknown function (DUF4823) 47 195 3.0E-60 T 13-09-2016 IPR032248 Protein of unknown function DUF4823 THL1_RS23200 20d172dc608032c711bc49c50d6dde0c 101 Pfam PF13467 Ribbon-helix-helix domain 16 83 5.1E-25 T 13-09-2016 IPR027373 Ribbon-helix-helix domain THL1_RS13470 7d727ce6fcae5a95c69bcbd93864e4c1 365 ProDom PD041438 LIPOPROTEIN YAIW PRECURSOR SIGNAL MEMBRANE OUTER LIPOPROTEIN ECS0428 XAC0592 SECRETED 20 361 7.0E-141 T 13-09-2016 IPR011673 Protein of unknown function DUF1615 THL1_RS13470 7d727ce6fcae5a95c69bcbd93864e4c1 365 Pfam PF07759 Protein of unknown function (DUF1615) 47 361 6.8E-145 T 13-09-2016 IPR011673 Protein of unknown function DUF1615 THL1_RS25540 2cb61ad0b864e06cebed141eef9f32a7 522 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 228 519 1.1E-131 T 13-09-2016 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type THL1_RS25540 2cb61ad0b864e06cebed141eef9f32a7 522 PANTHER PTHR11795:SF349 141 522 1.4E-177 T 13-09-2016 THL1_RS25540 2cb61ad0b864e06cebed141eef9f32a7 522 SUPERFAMILY SSF48371 117 223 2.59E-7 T 13-09-2016 IPR016024 Armadillo-type fold GO:0005488 THL1_RS25540 2cb61ad0b864e06cebed141eef9f32a7 522 Pfam PF02653 Branched-chain amino acid transport system / permease component 230 505 4.6E-53 T 13-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 THL1_RS25540 2cb61ad0b864e06cebed141eef9f32a7 522 PANTHER PTHR11795 141 522 1.4E-177 T 13-09-2016 THL1_RS22480 aaba0a45a87fb56ac2c8ab601661d064 343 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 30 79 1.7E-9 T 13-09-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain THL1_RS22480 aaba0a45a87fb56ac2c8ab601661d064 343 PANTHER PTHR33498 1 239 5.4E-23 T 13-09-2016 THL1_RS22480 aaba0a45a87fb56ac2c8ab601661d064 343 PANTHER PTHR33498:SF1 1 239 5.4E-23 T 13-09-2016 THL1_RS22480 aaba0a45a87fb56ac2c8ab601661d064 343 Pfam PF01610 Transposase 95 291 3.0E-50 T 13-09-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain THL1_RS11975 e9d6c01a0e2e5f9535cac305f04f8c1b 547 PANTHER PTHR30443:SF0 1 539 1.4E-261 T 13-09-2016 THL1_RS11975 e9d6c01a0e2e5f9535cac305f04f8c1b 547 SUPERFAMILY SSF53649 234 535 1.1E-20 T 13-09-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 THL1_RS11975 e9d6c01a0e2e5f9535cac305f04f8c1b 547 Pfam PF00884 Sulfatase 233 521 3.6E-50 T 13-09-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 THL1_RS11975 e9d6c01a0e2e5f9535cac305f04f8c1b 547 Pfam PF08019 Domain of unknown function (DUF1705) 54 203 2.4E-53 T 13-09-2016 IPR012549 Domain of unknown function DUF1705 GO:0016021 THL1_RS11975 e9d6c01a0e2e5f9535cac305f04f8c1b 547 Gene3D G3DSA:3.40.720.10 234 532 5.1E-11 T 13-09-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 THL1_RS11975 e9d6c01a0e2e5f9535cac305f04f8c1b 547 PANTHER PTHR30443 1 539 1.4E-261 T 13-09-2016 THL1_RS27710 38e4691431a0dd886e48bb4a49e4014d 154 PANTHER PTHR33420:SF1 1 154 2.4E-16 T 13-09-2016 THL1_RS27710 38e4691431a0dd886e48bb4a49e4014d 154 PANTHER PTHR33420 1 154 2.4E-16 T 13-09-2016 THL1_RS27710 38e4691431a0dd886e48bb4a49e4014d 154 Gene3D G3DSA:2.60.40.1090 6 154 8.0E-25 T 13-09-2016 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 THL1_RS27710 38e4691431a0dd886e48bb4a49e4014d 154 SUPERFAMILY SSF49401 6 153 4.92E-21 T 13-09-2016 IPR008966 Adhesion domain THL1_RS27710 38e4691431a0dd886e48bb4a49e4014d 154 Pfam PF00419 Fimbrial protein 3 154 3.4E-15 T 13-09-2016 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 THL1_RS21475 dd697a4fbf199685762da4b846dc80a3 219 PANTHER PTHR39327 4 211 1.7E-79 T 13-09-2016 THL1_RS21475 dd697a4fbf199685762da4b846dc80a3 219 SUPERFAMILY SSF54001 61 121 4.09E-7 T 13-09-2016 THL1_RS21475 dd697a4fbf199685762da4b846dc80a3 219 PANTHER PTHR39327:SF1 4 211 1.7E-79 T 13-09-2016 THL1_RS21475 dd697a4fbf199685762da4b846dc80a3 219 Pfam PF06035 Bacterial transglutaminase-like cysteine proteinase BTLCP 59 164 1.4E-17 T 13-09-2016 IPR010319 Transglutaminase-like cysteine peptidase, predicted THL1_RS18790 c98a50ae58c4d667a4076d1982fad7da 493 ProDom PD339107 ALGINATE ALG8 BIOSYNTHESIS TRANSFERASE TRANSMEMBRANE MEMBRANE 2.4.1.- GLYCOSYL GLYCOSYLTRANSFERASE PRECURSOR 1 478 0.0 T 13-09-2016 THL1_RS18790 c98a50ae58c4d667a4076d1982fad7da 493 Pfam PF13641 Glycosyltransferase like family 2 86 342 8.2E-54 T 13-09-2016 THL1_RS18790 c98a50ae58c4d667a4076d1982fad7da 493 SUPERFAMILY SSF53448 153 254 9.09E-12 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS18790 c98a50ae58c4d667a4076d1982fad7da 493 SUPERFAMILY SSF53448 285 358 9.09E-12 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS13095 dff6ec98c5c8905819edebd7f77a0e5e 415 Pfam PF13372 Alginate export 76 292 8.7E-7 T 13-09-2016 IPR025388 Alginate export domain UniPathway: UPA00286 THL1_RS13095 dff6ec98c5c8905819edebd7f77a0e5e 415 Gene3D G3DSA:2.40.160.10 47 415 4.0E-8 T 13-09-2016 IPR023614 Porin domain THL1_RS18215 a481eaa65a7ed6148fbd0333590343af 126 SUPERFAMILY SSF88723 3 120 1.82E-11 T 13-09-2016 IPR029060 PIN domain-like THL1_RS08800 67c3990bcdce454939969dae80880d75 234 SUPERFAMILY SSF75625 4 231 2.75E-72 T 13-09-2016 IPR029072 YebC-like THL1_RS08800 67c3990bcdce454939969dae80880d75 234 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 233 25.545 T 13-09-2016 IPR002876 Transcriptional regulator TACO1-like THL1_RS08800 67c3990bcdce454939969dae80880d75 234 Gene3D G3DSA:1.10.10.200 19 73 3.6E-23 T 13-09-2016 IPR017856 Integrase, N-terminal zinc-binding domain-like THL1_RS08800 67c3990bcdce454939969dae80880d75 234 Gene3D G3DSA:3.30.1270.10 78 128 5.0E-27 T 13-09-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 THL1_RS08800 67c3990bcdce454939969dae80880d75 234 Gene3D G3DSA:3.30.1270.10 206 231 5.0E-27 T 13-09-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 THL1_RS08800 67c3990bcdce454939969dae80880d75 234 Gene3D G3DSA:3.30.70.980 129 199 1.1E-18 T 13-09-2016 IPR026564 Transcriptional regulator TACO1-like, domain 3 THL1_RS08800 67c3990bcdce454939969dae80880d75 234 PANTHER PTHR12532 10 228 7.9E-74 T 13-09-2016 IPR002876 Transcriptional regulator TACO1-like THL1_RS08800 67c3990bcdce454939969dae80880d75 234 Pfam PF01709 Transcriptional regulator 9 228 1.0E-71 T 13-09-2016 IPR002876 Transcriptional regulator TACO1-like THL1_RS15980 587b3e27a02e9251ec9f223468adf6f4 393 Pfam PF07690 Major Facilitator Superfamily 19 264 1.0E-15 T 13-09-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THL1_RS15980 587b3e27a02e9251ec9f223468adf6f4 393 SUPERFAMILY SSF103473 14 390 7.59E-44 T 13-09-2016 IPR020846 Major facilitator superfamily domain THL1_RS15980 587b3e27a02e9251ec9f223468adf6f4 393 PANTHER PTHR23517 12 392 1.4E-121 T 13-09-2016 THL1_RS15980 587b3e27a02e9251ec9f223468adf6f4 393 Gene3D G3DSA:1.20.1250.20 15 197 3.1E-23 T 13-09-2016 THL1_RS15980 587b3e27a02e9251ec9f223468adf6f4 393 Gene3D G3DSA:1.20.1250.20 222 390 6.1E-14 T 13-09-2016 THL1_RS15980 587b3e27a02e9251ec9f223468adf6f4 393 PANTHER PTHR23517:SF4 12 392 1.4E-121 T 13-09-2016 THL1_RS08680 af75255dfe5a16404f3d8b8067ea6bcd 352 SUPERFAMILY SSF56784 41 286 1.52E-11 T 13-09-2016 IPR023214 HAD-like domain THL1_RS08680 af75255dfe5a16404f3d8b8067ea6bcd 352 Gene3D G3DSA:3.40.50.1000 164 225 6.8E-9 T 13-09-2016 IPR023214 HAD-like domain THL1_RS08680 af75255dfe5a16404f3d8b8067ea6bcd 352 Gene3D G3DSA:3.40.50.1000 43 66 6.8E-9 T 13-09-2016 IPR023214 HAD-like domain THL1_RS08680 af75255dfe5a16404f3d8b8067ea6bcd 352 Gene3D G3DSA:3.40.50.1000 257 293 6.8E-9 T 13-09-2016 IPR023214 HAD-like domain THL1_RS27690 6269669cb632c377cfe0075233b7ee33 324 Pfam PF02371 Transposase IS116/IS110/IS902 family 197 280 1.9E-21 T 13-09-2016 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THL1_RS27690 6269669cb632c377cfe0075233b7ee33 324 PANTHER PTHR33055:SF3 1 318 1.2E-61 T 13-09-2016 THL1_RS27690 6269669cb632c377cfe0075233b7ee33 324 Pfam PF01548 Transposase 5 153 1.0E-32 T 13-09-2016 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THL1_RS27690 6269669cb632c377cfe0075233b7ee33 324 PANTHER PTHR33055 1 318 1.2E-61 T 13-09-2016 THL1_RS06290 ff82208048f7fc2fce041bec8d262377 515 SUPERFAMILY SSF51126 168 436 2.44E-34 T 13-09-2016 IPR011050 Pectin lyase fold/virulence factor THL1_RS06290 ff82208048f7fc2fce041bec8d262377 515 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 367 404 4.3E-6 T 13-09-2016 IPR022441 Parallel beta-helix repeat-2 THL1_RS06290 ff82208048f7fc2fce041bec8d262377 515 SMART SM00722 234 394 2.2E-9 T 13-09-2016 IPR006633 Carbohydrate-binding/sugar hydrolysis domain THL1_RS06290 ff82208048f7fc2fce041bec8d262377 515 PANTHER PTHR22990 260 465 7.3E-21 T 13-09-2016 THL1_RS06290 ff82208048f7fc2fce041bec8d262377 515 SMART SM00710 350 372 2600.0 T 13-09-2016 IPR006626 Parallel beta-helix repeat THL1_RS06290 ff82208048f7fc2fce041bec8d262377 515 SMART SM00710 326 348 39.0 T 13-09-2016 IPR006626 Parallel beta-helix repeat THL1_RS06290 ff82208048f7fc2fce041bec8d262377 515 SMART SM00710 301 324 15.0 T 13-09-2016 IPR006626 Parallel beta-helix repeat THL1_RS06290 ff82208048f7fc2fce041bec8d262377 515 SMART SM00710 277 299 15.0 T 13-09-2016 IPR006626 Parallel beta-helix repeat THL1_RS06290 ff82208048f7fc2fce041bec8d262377 515 SMART SM00710 215 242 2300.0 T 13-09-2016 IPR006626 Parallel beta-helix repeat THL1_RS06290 ff82208048f7fc2fce041bec8d262377 515 SMART SM00710 373 395 3.5 T 13-09-2016 IPR006626 Parallel beta-helix repeat THL1_RS06290 ff82208048f7fc2fce041bec8d262377 515 Gene3D G3DSA:2.160.20.10 244 418 2.7E-14 T 13-09-2016 IPR012334 Pectin lyase fold THL1_RS06290 ff82208048f7fc2fce041bec8d262377 515 Pfam PF13229 Right handed beta helix region 307 414 9.5E-10 T 13-09-2016 THL1_RS18620 f99007170594df523c2e6eb73224956f 352 Gene3D G3DSA:3.60.15.10 144 174 4.6E-17 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS18620 f99007170594df523c2e6eb73224956f 352 Gene3D G3DSA:3.60.15.10 11 104 4.6E-17 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS18620 f99007170594df523c2e6eb73224956f 352 Gene3D G3DSA:3.60.15.10 214 310 4.6E-17 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS18620 f99007170594df523c2e6eb73224956f 352 SUPERFAMILY SSF56281 5 187 1.28E-23 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS18620 f99007170594df523c2e6eb73224956f 352 SUPERFAMILY SSF56281 220 317 1.28E-23 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS18620 f99007170594df523c2e6eb73224956f 352 Pfam PF00753 Metallo-beta-lactamase superfamily 23 82 6.6E-6 T 13-09-2016 IPR001279 Metallo-beta-lactamase THL1_RS06830 6b1de0ad4ecfa952d851eb906aca6295 102 PANTHER PTHR38598 2 102 1.4E-46 T 13-09-2016 THL1_RS06830 6b1de0ad4ecfa952d851eb906aca6295 102 Pfam PF04341 Protein of unknown function, DUF485 10 98 1.4E-35 T 13-09-2016 IPR007436 Protein of unknown function DUF485 THL1_RS13705 8e2fd2e86a7bdef1643a90e8053c33f8 136 PANTHER PTHR37950:SF1 2 115 4.1E-15 T 13-09-2016 THL1_RS13705 8e2fd2e86a7bdef1643a90e8053c33f8 136 Gene3D G3DSA:3.30.429.10 2 132 2.0E-36 T 13-09-2016 THL1_RS13705 8e2fd2e86a7bdef1643a90e8053c33f8 136 PANTHER PTHR37950 2 115 4.1E-15 T 13-09-2016 THL1_RS13705 8e2fd2e86a7bdef1643a90e8053c33f8 136 SUPERFAMILY SSF55331 2 120 5.13E-24 T 13-09-2016 IPR014347 Tautomerase/MIF superfamily THL1_RS13705 8e2fd2e86a7bdef1643a90e8053c33f8 136 Pfam PF02962 5-carboxymethyl-2-hydroxymuconate isomerase 2 114 4.0E-11 T 13-09-2016 IPR004220 5-carboxymethyl-2-hydroxymuconate isomerase GO:0008704|GO:0019439 KEGG: 00350+5.3.3.10|UniPathway: UPA00208 THL1_RS04140 2699792e2a87d0a47dca9cafd380e148 209 PANTHER PTHR30108 4 60 9.5E-87 T 13-09-2016 THL1_RS04140 2699792e2a87d0a47dca9cafd380e148 209 PANTHER PTHR30108 77 208 9.5E-87 T 13-09-2016 THL1_RS04140 2699792e2a87d0a47dca9cafd380e148 209 PANTHER PTHR30108:SF2 4 60 9.5E-87 T 13-09-2016 THL1_RS04140 2699792e2a87d0a47dca9cafd380e148 209 PANTHER PTHR30108:SF2 77 208 9.5E-87 T 13-09-2016 THL1_RS04140 2699792e2a87d0a47dca9cafd380e148 209 Gene3D G3DSA:3.40.50.1950 6 204 1.8E-74 T 13-09-2016 IPR003382 Flavoprotein GO:0003824 THL1_RS04140 2699792e2a87d0a47dca9cafd380e148 209 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 5 202 35.996 T 13-09-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 THL1_RS04140 2699792e2a87d0a47dca9cafd380e148 209 SUPERFAMILY SSF52507 6 202 2.75E-59 T 13-09-2016 IPR003382 Flavoprotein GO:0003824 THL1_RS04140 2699792e2a87d0a47dca9cafd380e148 209 Pfam PF02441 Flavoprotein 6 145 1.6E-26 T 13-09-2016 IPR003382 Flavoprotein GO:0003824 THL1_RS04140 2699792e2a87d0a47dca9cafd380e148 209 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 6 200 1.8E-61 T 13-09-2016 IPR004507 Flavin prenyltransferase UbiX/Pad1 THL1_RS10460 d6d31ccd8cdd07e3d730a1c0869cac36 333 Gene3D G3DSA:3.90.580.10 32 100 1.4E-5 T 13-09-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 THL1_RS10460 d6d31ccd8cdd07e3d730a1c0869cac36 333 SUPERFAMILY SSF57783 24 99 1.7E-6 T 13-09-2016 THL1_RS10460 d6d31ccd8cdd07e3d730a1c0869cac36 333 Pfam PF13362 Toprim domain 227 323 1.2E-11 T 13-09-2016 IPR006171 Toprim domain THL1_RS13845 066da076246f27c69961fa2374f86b3d 188 SUPERFAMILY SSF52096 32 181 5.07E-10 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS13845 066da076246f27c69961fa2374f86b3d 188 Gene3D G3DSA:3.90.226.10 72 118 1.1E-4 T 13-09-2016 IPR029045 ClpP/crotonase-like domain THL1_RS23255 b3ac750f9ef5f45a3a7810362d791d9d 294 SUPERFAMILY SSF56645 70 166 2.88E-13 T 13-09-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 THL1_RS23255 b3ac750f9ef5f45a3a7810362d791d9d 294 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 90 162 1.7E-8 T 13-09-2016 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0003995|GO:0055114 THL1_RS23255 b3ac750f9ef5f45a3a7810362d791d9d 294 Gene3D G3DSA:2.40.110.10 85 165 6.9E-9 T 13-09-2016 THL1_RS09065 af0b43481f731581e7072cf6f368590c 244 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 244 49.289 T 13-09-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148 THL1_RS09065 af0b43481f731581e7072cf6f368590c 244 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 7 238 1.6E-40 T 13-09-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148 THL1_RS09065 af0b43481f731581e7072cf6f368590c 244 PANTHER PTHR34148 4 241 2.1E-53 T 13-09-2016 THL1_RS09065 af0b43481f731581e7072cf6f368590c 244 PANTHER PTHR34148:SF1 4 241 2.1E-53 T 13-09-2016 THL1_RS09065 af0b43481f731581e7072cf6f368590c 244 Pfam PF02654 Cobalamin-5-phosphate synthase 7 237 2.5E-54 T 13-09-2016 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269|UniPathway: UPA00148 THL1_RS26565 421f7bef2e53494508d8b56e50b9d499 454 Pfam PF01979 Amidohydrolase family 48 429 4.7E-38 T 13-09-2016 IPR006680 Amidohydrolase-related GO:0016787 THL1_RS26565 421f7bef2e53494508d8b56e50b9d499 454 PANTHER PTHR11271:SF4 15 454 2.9E-207 T 13-09-2016 IPR010252 Formiminoglutamate deiminase THL1_RS26565 421f7bef2e53494508d8b56e50b9d499 454 Gene3D G3DSA:2.30.40.10 388 432 4.6E-4 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS26565 421f7bef2e53494508d8b56e50b9d499 454 SUPERFAMILY SSF51338 360 435 9.26E-13 T 13-09-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 THL1_RS26565 421f7bef2e53494508d8b56e50b9d499 454 Gene3D G3DSA:3.20.20.140 54 387 2.7E-81 T 13-09-2016 THL1_RS26565 421f7bef2e53494508d8b56e50b9d499 454 PANTHER PTHR11271 15 454 2.9E-207 T 13-09-2016 THL1_RS26565 421f7bef2e53494508d8b56e50b9d499 454 SUPERFAMILY SSF51556 51 375 1.67E-74 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS26565 421f7bef2e53494508d8b56e50b9d499 454 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 1 452 1.5E-222 T 13-09-2016 IPR010252 Formiminoglutamate deiminase THL1_RS16600 2309d5dce422d208063599116f12b7be 516 PANTHER PTHR35004:SF2 3 451 9.9E-88 T 13-09-2016 THL1_RS16600 2309d5dce422d208063599116f12b7be 516 SUPERFAMILY SSF53098 133 300 7.84E-11 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS16600 2309d5dce422d208063599116f12b7be 516 Gene3D G3DSA:3.30.420.10 133 298 8.7E-10 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS16600 2309d5dce422d208063599116f12b7be 516 PANTHER PTHR35004 3 451 9.9E-88 T 13-09-2016 THL1_RS16600 2309d5dce422d208063599116f12b7be 516 Pfam PF00665 Integrase core domain 134 264 1.1E-15 T 13-09-2016 IPR001584 Integrase, catalytic core GO:0015074 THL1_RS09650 420da0fee1371f13fb22a7ca1f0965c8 199 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 13-09-2016 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 THL1_RS09650 420da0fee1371f13fb22a7ca1f0965c8 199 SUPERFAMILY SSF111304 3 197 7.85E-69 T 13-09-2016 IPR023627 Recombination protein RecR THL1_RS09650 420da0fee1371f13fb22a7ca1f0965c8 199 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 99.304 T 13-09-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 THL1_RS09650 420da0fee1371f13fb22a7ca1f0965c8 199 Gene3D G3DSA:1.10.150.20 11 33 4.6E-4 T 13-09-2016 THL1_RS09650 420da0fee1371f13fb22a7ca1f0965c8 199 Pfam PF02132 RecR protein 41 78 2.3E-16 T 13-09-2016 IPR023628 Recombination protein RecR, C4-type zinc finger THL1_RS09650 420da0fee1371f13fb22a7ca1f0965c8 199 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 2.3E-72 T 13-09-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 THL1_RS09650 420da0fee1371f13fb22a7ca1f0965c8 199 PANTHER PTHR30446 1 199 4.4E-110 T 13-09-2016 THL1_RS09650 420da0fee1371f13fb22a7ca1f0965c8 199 PANTHER PTHR30446:SF0 1 199 4.4E-110 T 13-09-2016 THL1_RS09650 420da0fee1371f13fb22a7ca1f0965c8 199 SMART SM00493 80 164 7.5E-12 T 13-09-2016 IPR006171 Toprim domain THL1_RS09650 420da0fee1371f13fb22a7ca1f0965c8 199 Pfam PF13662 Toprim domain 82 170 4.6E-22 T 13-09-2016 IPR006171 Toprim domain THL1_RS10960 70d1e90b1543d64cdbdba83babba76c0 154 Pfam PF12975 Domain of unknown function (DUF3859) 24 153 1.7E-42 T 13-09-2016 IPR024331 Domain of unknown function DUF3859 THL1_RS06295 9e0d6c36c8c6fbd54bc26c1afacb9e1f 481 Pfam PF13372 Alginate export 29 476 4.7E-101 T 13-09-2016 IPR025388 Alginate export domain UniPathway: UPA00286 THL1_RS09840 73c8c571a4d45a966490f0b19fd849c1 296 PANTHER PTHR22916 1 217 3.3E-28 T 13-09-2016 THL1_RS09840 73c8c571a4d45a966490f0b19fd849c1 296 Pfam PF00535 Glycosyl transferase family 2 4 125 6.2E-23 T 13-09-2016 IPR001173 Glycosyltransferase 2-like THL1_RS09840 73c8c571a4d45a966490f0b19fd849c1 296 Gene3D G3DSA:3.90.550.10 1 207 2.4E-30 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS09840 73c8c571a4d45a966490f0b19fd849c1 296 SUPERFAMILY SSF53448 2 203 6.54E-38 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS12810 bcbfacb8ae7a1cb2d0bb65027c2cc1bb 262 Pfam PF09836 Putative DNA-binding domain 6 101 1.1E-21 T 13-09-2016 IPR018640 Putative DNA-binding domain, bacteria THL1_RS23895 bf33db7123ab0e6a46db0d3ccccc8e05 302 Gene3D G3DSA:3.90.25.10 199 246 1.3E-5 T 13-09-2016 THL1_RS23895 bf33db7123ab0e6a46db0d3ccccc8e05 302 Pfam PF08338 Domain of unknown function (DUF1731) 250 296 1.6E-17 T 13-09-2016 IPR013549 Domain of unknown function DUF1731 THL1_RS23895 bf33db7123ab0e6a46db0d3ccccc8e05 302 PANTHER PTHR11092 1 302 1.1E-138 T 13-09-2016 IPR010099 Epimerase family protein SDR39U1 THL1_RS23895 bf33db7123ab0e6a46db0d3ccccc8e05 302 Gene3D G3DSA:3.40.50.720 1 198 1.0E-18 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23895 bf33db7123ab0e6a46db0d3ccccc8e05 302 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 222 1.0E-22 T 13-09-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 THL1_RS23895 bf33db7123ab0e6a46db0d3ccccc8e05 302 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 293 3.6E-106 T 13-09-2016 IPR010099 Epimerase family protein SDR39U1 THL1_RS23895 bf33db7123ab0e6a46db0d3ccccc8e05 302 SUPERFAMILY SSF51735 1 296 2.58E-42 T 13-09-2016 IPR016040 NAD(P)-binding domain THL1_RS23895 bf33db7123ab0e6a46db0d3ccccc8e05 302 PANTHER PTHR11092:SF0 1 302 1.1E-138 T 13-09-2016 THL1_RS11435 dfeab3a249d3ffabd420aa191190daff 549 PANTHER PTHR11819 28 538 6.7E-242 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS11435 dfeab3a249d3ffabd420aa191190daff 549 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 59 468 7.4E-60 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS11435 dfeab3a249d3ffabd420aa191190daff 549 PANTHER PTHR11819:SF13 28 538 6.7E-242 T 13-09-2016 THL1_RS11435 dfeab3a249d3ffabd420aa191190daff 549 Pfam PF00474 Sodium:solute symporter family 59 468 2.6E-108 T 13-09-2016 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS11435 dfeab3a249d3ffabd420aa191190daff 549 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 174 199 - T 13-09-2016 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 THL1_RS09850 b1706cb12ac5dac8a9666e183934959e 198 PANTHER PTHR30576 2 185 1.9E-102 T 13-09-2016 THL1_RS09850 b1706cb12ac5dac8a9666e183934959e 198 PANTHER PTHR30576:SF8 2 185 1.9E-102 T 13-09-2016 THL1_RS09850 b1706cb12ac5dac8a9666e183934959e 198 Pfam PF02397 Bacterial sugar transferase 3 177 1.5E-58 T 13-09-2016 IPR003362 Bacterial sugar transferase THL1_RS04730 47c6eb842fed1975bd7f73d369d4e211 168 Pfam PF11220 Protein of unknown function (DUF3015) 25 163 1.1E-52 T 13-09-2016 IPR021383 Protein of unknown function DUF3015 THL1_RS23570 006c6a30023df1fcdb0fec64516dd48f 274 PANTHER PTHR10992 1 272 1.1E-88 T 13-09-2016 THL1_RS23570 006c6a30023df1fcdb0fec64516dd48f 274 PRINTS PR00412 Epoxide hydrolase signature 88 101 3.2E-7 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS23570 006c6a30023df1fcdb0fec64516dd48f 274 PRINTS PR00412 Epoxide hydrolase signature 247 269 3.2E-7 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS23570 006c6a30023df1fcdb0fec64516dd48f 274 PRINTS PR00412 Epoxide hydrolase signature 23 41 3.2E-7 T 13-09-2016 IPR000639 Epoxide hydrolase-like GO:0003824 THL1_RS23570 006c6a30023df1fcdb0fec64516dd48f 274 PANTHER PTHR10992:SF800 1 272 1.1E-88 T 13-09-2016 THL1_RS23570 006c6a30023df1fcdb0fec64516dd48f 274 Pfam PF00561 alpha/beta hydrolase fold 18 120 2.7E-19 T 13-09-2016 IPR000073 Alpha/beta hydrolase fold-1 THL1_RS23570 006c6a30023df1fcdb0fec64516dd48f 274 Gene3D G3DSA:3.40.50.1820 2 270 2.6E-59 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS23570 006c6a30023df1fcdb0fec64516dd48f 274 SUPERFAMILY SSF53474 2 269 3.01E-58 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS24575 a759eec7545d29f39932cd3321d8b1a2 277 PANTHER PTHR30514 2 211 4.8E-19 T 13-09-2016 THL1_RS24575 a759eec7545d29f39932cd3321d8b1a2 277 SUPERFAMILY SSF53697 95 227 8.58E-7 T 13-09-2016 THL1_RS24575 a759eec7545d29f39932cd3321d8b1a2 277 Gene3D G3DSA:1.10.10.10 5 62 2.8E-17 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS24575 a759eec7545d29f39932cd3321d8b1a2 277 PANTHER PTHR30514:SF4 2 211 4.8E-19 T 13-09-2016 THL1_RS24575 a759eec7545d29f39932cd3321d8b1a2 277 Gene3D G3DSA:3.40.50.10490 63 162 7.3E-7 T 13-09-2016 THL1_RS24575 a759eec7545d29f39932cd3321d8b1a2 277 SUPERFAMILY SSF46689 6 73 1.43E-13 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS24575 a759eec7545d29f39932cd3321d8b1a2 277 Pfam PF01418 Helix-turn-helix domain, rpiR family 4 73 4.8E-10 T 13-09-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 THL1_RS20350 5651b4e66a5ed2a69036535ff61c0a20 245 Pfam PF13795 HupE / UreJ protein 61 212 4.7E-52 T 13-09-2016 IPR032809 Putative HupE/UreJ protein THL1_RS14660 87dee493d119c68bb52253827dadbada 219 Pfam PF04191 Phospholipid methyltransferase 126 194 1.1E-9 T 13-09-2016 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|UniPathway: UPA00753 THL1_RS14660 87dee493d119c68bb52253827dadbada 219 PANTHER PTHR12714:SF11 8 212 1.1E-22 T 13-09-2016 THL1_RS14660 87dee493d119c68bb52253827dadbada 219 PANTHER PTHR12714 8 212 1.1E-22 T 13-09-2016 THL1_RS07735 b2302b9280ea08b1c787fe78c06074a8 245 Gene3D G3DSA:3.40.30.10 79 154 4.0E-7 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS07735 b2302b9280ea08b1c787fe78c06074a8 245 Pfam PF05988 Bacterial protein of unknown function (DUF899) 5 232 3.4E-91 T 13-09-2016 IPR010296 Protein of unknown function DUF899, thioredoxin-like THL1_RS07735 b2302b9280ea08b1c787fe78c06074a8 245 SUPERFAMILY SSF52833 59 151 5.18E-9 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS00480 f2b507ba26b7fcf97184261cb1e2e255 643 Pfam PF13387 Domain of unknown function (DUF4105) 264 433 5.6E-29 T 13-09-2016 IPR025178 Domain of unknown function DUF4105 THL1_RS25085 c6282316d00f21c5e06bd74710cea745 388 PANTHER PTHR30158 30 382 1.5E-113 T 13-09-2016 THL1_RS25085 c6282316d00f21c5e06bd74710cea745 388 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 36 373 2.0E-79 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS25085 c6282316d00f21c5e06bd74710cea745 388 SUPERFAMILY SSF111369 50 296 1.57E-68 T 13-09-2016 THL1_RS25085 c6282316d00f21c5e06bd74710cea745 388 Pfam PF00529 HlyD membrane-fusion protein of T1SS 36 358 4.1E-6 T 13-09-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 THL1_RS25085 c6282316d00f21c5e06bd74710cea745 388 Gene3D G3DSA:2.40.50.100 61 94 8.0E-20 T 13-09-2016 THL1_RS25085 c6282316d00f21c5e06bd74710cea745 388 Gene3D G3DSA:2.40.50.100 169 200 8.0E-20 T 13-09-2016 THL1_RS25085 c6282316d00f21c5e06bd74710cea745 388 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 62 292 5.8E-15 T 13-09-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THL1_RS25085 c6282316d00f21c5e06bd74710cea745 388 PANTHER PTHR30158:SF3 30 382 1.5E-113 T 13-09-2016 THL1_RS10710 e4d3cb0e5b4871f4e5fdda31256f9bef 202 TIGRFAM TIGR01940 nqrE: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit 2 201 7.4E-106 T 13-09-2016 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 THL1_RS10710 e4d3cb0e5b4871f4e5fdda31256f9bef 202 PANTHER PTHR30335 2 202 2.1E-137 T 13-09-2016 THL1_RS10710 e4d3cb0e5b4871f4e5fdda31256f9bef 202 Hamap MF_00429 Na(+)-translocating NADH-quinone reductase subunit E [nqrE]. 1 202 29.052 T 13-09-2016 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 THL1_RS10710 e4d3cb0e5b4871f4e5fdda31256f9bef 202 PANTHER PTHR30335:SF1 2 202 2.1E-137 T 13-09-2016 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E GO:0009276|GO:0016021|GO:0016655|GO:0022904|GO:0055114 THL1_RS10710 e4d3cb0e5b4871f4e5fdda31256f9bef 202 PIRSF PIRSF006102 1 202 6.7E-59 T 13-09-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 THL1_RS10710 e4d3cb0e5b4871f4e5fdda31256f9bef 202 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 200 3.1E-56 T 13-09-2016 IPR003667 Rnf-Nqr subunit, membrane protein GO:0016020 THL1_RS21825 a5f713db9ef0c455082f5595ff64d3ec 217 PANTHER PTHR10681 3 217 2.6E-88 T 13-09-2016 THL1_RS21825 a5f713db9ef0c455082f5595ff64d3ec 217 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 163 202 9.6E-16 T 13-09-2016 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS21825 a5f713db9ef0c455082f5595ff64d3ec 217 PANTHER PTHR10681:SF99 3 217 2.6E-88 T 13-09-2016 THL1_RS21825 a5f713db9ef0c455082f5595ff64d3ec 217 SUPERFAMILY SSF52833 3 214 7.47E-71 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS21825 a5f713db9ef0c455082f5595ff64d3ec 217 Gene3D G3DSA:3.30.1020.10 165 217 3.5E-28 T 13-09-2016 THL1_RS21825 a5f713db9ef0c455082f5595ff64d3ec 217 Pfam PF00578 AhpC/TSA family 5 142 1.2E-29 T 13-09-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 THL1_RS21825 a5f713db9ef0c455082f5595ff64d3ec 217 PIRSF PIRSF000239 1 215 7.0E-79 T 13-09-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 THL1_RS21825 a5f713db9ef0c455082f5595ff64d3ec 217 Gene3D G3DSA:3.40.30.10 4 164 1.5E-60 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS00290 1f4492a798648f1022e4553daaa4eaf4 301 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 17 295 2.0E-104 T 13-09-2016 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 UniPathway: UPA00834 THL1_RS00290 1f4492a798648f1022e4553daaa4eaf4 301 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 15 296 19.941 T 13-09-2016 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 UniPathway: UPA00834 THL1_RS00290 1f4492a798648f1022e4553daaa4eaf4 301 PANTHER PTHR11048:SF3 11 295 9.5E-84 T 13-09-2016 THL1_RS00290 1f4492a798648f1022e4553daaa4eaf4 301 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 70 92 - T 13-09-2016 IPR030470 UbiA prenyltransferase conserved site THL1_RS00290 1f4492a798648f1022e4553daaa4eaf4 301 Pfam PF01040 UbiA prenyltransferase family 32 284 3.5E-61 T 13-09-2016 IPR000537 UbiA prenyltransferase family GO:0004659|GO:0016021 THL1_RS00290 1f4492a798648f1022e4553daaa4eaf4 301 PANTHER PTHR11048 11 295 9.5E-84 T 13-09-2016 THL1_RS01460 3f9fc9a54f253d2011104e054c9090df 152 Pfam PF10027 Predicted integral membrane protein (DUF2269) 6 151 2.6E-29 T 13-09-2016 IPR018729 Protein of unknown function DUF2269, transmembrane THL1_RS12880 f9674429cdaeb6ea9bf76796d78448e1 299 PANTHER PTHR33281 8 282 5.0E-61 T 13-09-2016 THL1_RS12880 f9674429cdaeb6ea9bf76796d78448e1 299 Pfam PF01062 Bestrophin, RFP-TM, chloride channel 1 278 4.5E-60 T 13-09-2016 IPR021134 Bestrophin/UPF0187 THL1_RS16115 03641b92885580428e4f499b7fa28a85 104 TIGRFAM TIGR01594 holin_lambda: phage holin, lambda family 1 98 4.8E-25 T 13-09-2016 IPR006481 Bacteriophage lambda, GpS, holin THL1_RS16115 03641b92885580428e4f499b7fa28a85 104 Pfam PF05106 Phage holin family (Lysis protein S) 3 98 8.8E-30 T 13-09-2016 IPR006481 Bacteriophage lambda, GpS, holin THL1_RS22750 4783ccb335ab2d12b4d1b0a03d4832c6 104 Pfam PF09619 Type III secretion system lipoprotein chaperone (YscW) 21 91 2.2E-21 T 13-09-2016 THL1_RS22750 4783ccb335ab2d12b4d1b0a03d4832c6 104 PANTHER PTHR38013 21 104 6.4E-19 T 13-09-2016 THL1_RS08350 8772d096c859ecfdfff8c3c46280ffe9 263 TIGRFAM TIGR01267 Phe4hydrox_mono: phenylalanine-4-hydroxylase 11 254 9.6E-129 T 13-09-2016 IPR005960 Phenylalanine-4-hydroxylase, monomeric form GO:0004505|GO:0006559|GO:0055114 KEGG: 00360+1.14.16.1|KEGG: 00400+1.14.16.1|MetaCyc: PWY-6134|MetaCyc: PWY-7158|UniPathway: UPA00139 THL1_RS08350 8772d096c859ecfdfff8c3c46280ffe9 263 ProSitePatterns PS00367 Biopterin-dependent aromatic amino acid hydroxylases signature. 117 128 - T 13-09-2016 IPR018301 Aromatic amino acid hydroxylase, iron/copper binding site GO:0004497|GO:0005506|GO:0009072|GO:0055114 THL1_RS08350 8772d096c859ecfdfff8c3c46280ffe9 263 SUPERFAMILY SSF56534 3 249 1.1E-100 T 13-09-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 THL1_RS08350 8772d096c859ecfdfff8c3c46280ffe9 263 Pfam PF00351 Biopterin-dependent aromatic amino acid hydroxylase 15 229 1.3E-45 T 13-09-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 THL1_RS08350 8772d096c859ecfdfff8c3c46280ffe9 263 PANTHER PTHR11473 9 224 3.2E-91 T 13-09-2016 IPR001273 Aromatic amino acid hydroxylase GO:0004497|GO:0005506|GO:0009072|GO:0055114 THL1_RS08350 8772d096c859ecfdfff8c3c46280ffe9 263 Gene3D G3DSA:1.10.800.10 4 245 1.6E-92 T 13-09-2016 IPR001273 Aromatic amino acid hydroxylase GO:0004497|GO:0005506|GO:0009072|GO:0055114 THL1_RS08350 8772d096c859ecfdfff8c3c46280ffe9 263 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 138 157 9.5E-9 T 13-09-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 THL1_RS08350 8772d096c859ecfdfff8c3c46280ffe9 263 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 74 96 9.5E-9 T 13-09-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 THL1_RS08350 8772d096c859ecfdfff8c3c46280ffe9 263 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 178 196 9.5E-9 T 13-09-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 THL1_RS08350 8772d096c859ecfdfff8c3c46280ffe9 263 PRINTS PR00372 Biopterin-dependent aromatic amino acid hydroxylase signature 209 228 9.5E-9 T 13-09-2016 IPR019774 Aromatic amino acid hydroxylase, C-terminal GO:0016714|GO:0055114 THL1_RS00605 d940d6d22db4cfbe7e110f4f7bc89c9d 247 Pfam PF00589 Phage integrase family 166 246 3.6E-8 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS00605 d940d6d22db4cfbe7e110f4f7bc89c9d 247 Gene3D G3DSA:1.10.443.10 164 247 2.1E-12 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS00605 d940d6d22db4cfbe7e110f4f7bc89c9d 247 SUPERFAMILY SSF56349 61 247 4.12E-28 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS06270 7096f08fc5c7c050e157b3886de1e1dc 382 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 81 346 3.5E-92 T 13-09-2016 IPR031811 AlgX, SGNH hydrolase-like domain KEGG: 00061+2.3.1.-|KEGG: 00253+2.3.1.-|KEGG: 00261+2.3.1.-|KEGG: 00310+2.3.1.-|KEGG: 00330+2.3.1.-|KEGG: 00332+2.3.1.-|KEGG: 00340+2.3.1.-|KEGG: 00350+2.3.1.-|KEGG: 00564+2.3.1.-|KEGG: 00565+2.3.1.-|KEGG: 00604+2.3.1.-|KEGG: 00623+2.3.1.-|KEGG: 00626+2.3.1.-|KEGG: 00627+2.3.1.-|KEGG: 00642+2.3.1.-|KEGG: 00650+2.3.1.-|KEGG: 00680+2.3.1.-|KEGG: 00903+2.3.1.-|KEGG: 00904+2.3.1.-|KEGG: 00906+2.3.1.-|KEGG: 00940+2.3.1.-|KEGG: 00942+2.3.1.-|KEGG: 00950+2.3.1.-|KEGG: 00960+2.3.1.-|KEGG: 00965+2.3.1.-|UniPathway: UPA00286 THL1_RS26305 e3918dfe0c1e33469542449ef3ee6dd8 177 Pfam PF04351 Pilus assembly protein, PilP 29 173 1.1E-50 T 13-09-2016 IPR007446 Pilus assembly protein PilP THL1_RS26305 e3918dfe0c1e33469542449ef3ee6dd8 177 PIRSF PIRSF016481 4 177 4.4E-66 T 13-09-2016 IPR007446 Pilus assembly protein PilP THL1_RS24360 54fd9aca0d3da3d645691d2fa54157bc 484 PANTHER PTHR22936 144 288 8.2E-22 T 13-09-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 THL1_RS24360 54fd9aca0d3da3d645691d2fa54157bc 484 Pfam PF01694 Rhomboid family 140 288 1.5E-24 T 13-09-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 THL1_RS24360 54fd9aca0d3da3d645691d2fa54157bc 484 SUPERFAMILY SSF144091 134 290 2.35E-37 T 13-09-2016 THL1_RS24360 54fd9aca0d3da3d645691d2fa54157bc 484 SUPERFAMILY SSF144091 12 49 2.35E-37 T 13-09-2016 THL1_RS24360 54fd9aca0d3da3d645691d2fa54157bc 484 Gene3D G3DSA:1.20.1540.10 134 287 7.6E-35 T 13-09-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 THL1_RS24360 54fd9aca0d3da3d645691d2fa54157bc 484 Gene3D G3DSA:1.20.1540.10 14 56 7.6E-35 T 13-09-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 THL1_RS16980 7662850041a5f4a46d6b2b019f785206 422 PANTHER PTHR34596 1 422 1.1E-166 T 13-09-2016 THL1_RS16980 7662850041a5f4a46d6b2b019f785206 422 Gene3D G3DSA:2.40.160.10 32 422 1.5E-150 T 13-09-2016 IPR023614 Porin domain THL1_RS16980 7662850041a5f4a46d6b2b019f785206 422 Pfam PF03573 outer membrane porin, OprD family 30 420 4.2E-153 T 13-09-2016 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 THL1_RS23635 e25ecf3c6e6c6f6c7f35a7a5f163fcfc 255 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 11 227 7.2E-36 T 13-09-2016 THL1_RS23635 e25ecf3c6e6c6f6c7f35a7a5f163fcfc 255 PANTHER PTHR37468 1 247 3.7E-90 T 13-09-2016 THL1_RS23635 e25ecf3c6e6c6f6c7f35a7a5f163fcfc 255 Hamap MF_00468 Sulfate transporter CysZ [cysZ]. 5 245 27.525 T 13-09-2016 IPR022985 Sulfate transporter CysZ GO:0000103|GO:0005887|GO:0015116 THL1_RS25950 3d580f885caacc188fed01f36df005b4 237 SUPERFAMILY SSF159594 29 189 6.54E-25 T 13-09-2016 THL1_RS25950 3d580f885caacc188fed01f36df005b4 237 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 31 186 1.0E-39 T 13-09-2016 IPR005586 ABC-type transport auxiliary lipoprotein component THL1_RS25950 3d580f885caacc188fed01f36df005b4 237 Gene3D G3DSA:3.40.50.10610 19 190 5.1E-17 T 13-09-2016 IPR005586 ABC-type transport auxiliary lipoprotein component THL1_RS04875 4a35f01bceb1f80a3d91adaf57ef99bc 315 Pfam PF02401 LytB protein 3 283 1.5E-93 T 13-09-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UniPathway: UPA00056|UniPathway: UPA00059 THL1_RS04875 4a35f01bceb1f80a3d91adaf57ef99bc 315 PANTHER PTHR30426 1 312 1.4E-157 T 13-09-2016 THL1_RS04875 4a35f01bceb1f80a3d91adaf57ef99bc 315 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2 285 2.0E-98 T 13-09-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UniPathway: UPA00056|UniPathway: UPA00059 THL1_RS04875 4a35f01bceb1f80a3d91adaf57ef99bc 315 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 287 38.035 T 13-09-2016 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 UniPathway: UPA00056|UniPathway: UPA00059 THL1_RS07590 773d319dbaf4e5a6c894b1a3bf9597a0 417 Pfam PF01547 Bacterial extracellular solute-binding protein 39 293 3.1E-27 T 13-09-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 THL1_RS07590 773d319dbaf4e5a6c894b1a3bf9597a0 417 PANTHER PTHR30061:SF22 20 416 3.4E-131 T 13-09-2016 THL1_RS07590 773d319dbaf4e5a6c894b1a3bf9597a0 417 Gene3D G3DSA:3.40.190.10 159 343 1.6E-30 T 13-09-2016 THL1_RS07590 773d319dbaf4e5a6c894b1a3bf9597a0 417 SUPERFAMILY SSF53850 24 415 3.86E-63 T 13-09-2016 THL1_RS07590 773d319dbaf4e5a6c894b1a3bf9597a0 417 PANTHER PTHR30061 20 416 3.4E-131 T 13-09-2016 THL1_RS07590 773d319dbaf4e5a6c894b1a3bf9597a0 417 Gene3D G3DSA:3.40.190.10 28 158 1.2E-8 T 13-09-2016 THL1_RS15610 a6848b6ad71d321cec67f391366275af 539 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 13-09-2016 IPR020845 AMP-binding, conserved site THL1_RS15610 a6848b6ad71d321cec67f391366275af 539 Gene3D G3DSA:3.40.50.980 39 186 2.7E-35 T 13-09-2016 THL1_RS15610 a6848b6ad71d321cec67f391366275af 539 PANTHER PTHR24095 403 532 2.2E-167 T 13-09-2016 THL1_RS15610 a6848b6ad71d321cec67f391366275af 539 PANTHER PTHR24095 29 387 2.2E-167 T 13-09-2016 THL1_RS15610 a6848b6ad71d321cec67f391366275af 539 Gene3D G3DSA:3.40.50.980 187 341 1.5E-28 T 13-09-2016 THL1_RS15610 a6848b6ad71d321cec67f391366275af 539 SUPERFAMILY SSF56801 28 530 3.4E-138 T 13-09-2016 THL1_RS15610 a6848b6ad71d321cec67f391366275af 539 Gene3D G3DSA:3.30.300.30 427 528 6.7E-30 T 13-09-2016 THL1_RS15610 a6848b6ad71d321cec67f391366275af 539 Gene3D G3DSA:2.30.38.10 352 426 3.3E-8 T 13-09-2016 THL1_RS15610 a6848b6ad71d321cec67f391366275af 539 Pfam PF13193 AMP-binding enzyme C-terminal domain 442 519 4.5E-24 T 13-09-2016 IPR025110 AMP-binding enzyme C-terminal domain THL1_RS15610 a6848b6ad71d321cec67f391366275af 539 Pfam PF00501 AMP-binding enzyme 39 432 1.4E-75 T 13-09-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 THL1_RS28305 0051bc6deb661c7374a369df3f98891c 264 SUPERFAMILY SSF53850 16 240 2.28E-17 T 13-09-2016 THL1_RS28305 0051bc6deb661c7374a369df3f98891c 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 29 232 3.6E-6 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS12160 bb22c058f7af1a714551b4e8944a81ec 116 Gene3D G3DSA:3.30.10.10 60 112 1.8E-4 T 13-09-2016 THL1_RS12160 bb22c058f7af1a714551b4e8944a81ec 116 Pfam PF11720 Peptidase inhibitor I78 family 52 116 2.2E-15 T 13-09-2016 IPR021719 Proteinase inhibitor I78 THL1_RS12160 bb22c058f7af1a714551b4e8944a81ec 116 PANTHER PTHR39600 9 116 1.1E-17 T 13-09-2016 THL1_RS07135 7538b3fddc730ccb84c68f358f50faf9 129 SUPERFAMILY SSF54427 1 122 2.99E-27 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS07135 7538b3fddc730ccb84c68f358f50faf9 129 Gene3D G3DSA:3.10.450.50 3 125 7.2E-34 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS07135 7538b3fddc730ccb84c68f358f50faf9 129 Pfam PF12680 SnoaL-like domain 13 113 8.2E-12 T 13-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain THL1_RS08170 e550c3a1eada9e217916695291efa989 154 Pfam PF05425 Copper resistance protein D 49 150 2.6E-16 T 13-09-2016 IPR008457 Copper resistance protein D GO:0016021 THL1_RS22245 e14838693605ae060beec0da8cf37d1a 364 Pfam PF01594 Domain of unknown function DUF20 13 339 8.3E-51 T 13-09-2016 IPR002549 Transmembrane protein TqsA-like THL1_RS22245 e14838693605ae060beec0da8cf37d1a 364 PANTHER PTHR21716 13 360 2.6E-61 T 13-09-2016 IPR002549 Transmembrane protein TqsA-like THL1_RS05760 6025effdfc80f06fbfe4bfc3cb3b3845 334 Pfam PF04338 Protein of unknown function, DUF481 127 334 9.3E-49 T 13-09-2016 IPR007433 Protein of unknown function DUF481 THL1_RS24925 5662165dcd635fff3d1e0a11a8cd91dc 86 Pfam PF11731 Pathogenicity locus 15 61 8.2E-6 T 13-09-2016 IPR021725 Pathogenicity locus THL1_RS24925 5662165dcd635fff3d1e0a11a8cd91dc 86 Gene3D G3DSA:1.10.150.20 17 64 5.0E-7 T 13-09-2016 THL1_RS27865 4d102106ce5068a427e816053a6c288c 121 Pfam PF09685 Domain of unknown function (DUF4870) 15 120 4.8E-41 T 13-09-2016 IPR019109 Protein of unknown function DUF4870 THL1_RS18240 215ec28c663b56bb4cbc3a36ba8d6800 227 Gene3D G3DSA:3.40.50.1000 1 219 1.4E-24 T 13-09-2016 IPR023214 HAD-like domain THL1_RS18240 215ec28c663b56bb4cbc3a36ba8d6800 227 PANTHER PTHR20371 1 207 5.5E-108 T 13-09-2016 THL1_RS18240 215ec28c663b56bb4cbc3a36ba8d6800 227 SUPERFAMILY SSF56784 1 221 2.7E-62 T 13-09-2016 IPR023214 HAD-like domain THL1_RS18240 215ec28c663b56bb4cbc3a36ba8d6800 227 TIGRFAM TIGR01691 enolase-ppase: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 3 208 1.6E-78 T 13-09-2016 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|UniPathway: UPA00904|UniPathway: UPA00904 THL1_RS18240 215ec28c663b56bb4cbc3a36ba8d6800 227 Hamap MF_01681 Enolase-phosphatase E1 [mtnC]. 2 222 42.715 T 13-09-2016 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|UniPathway: UPA00904|UniPathway: UPA00904 THL1_RS01740 272ce43ee89a206a7c1b0a6efda3c683 285 PANTHER PTHR30177 11 279 7.3E-85 T 13-09-2016 THL1_RS01740 272ce43ee89a206a7c1b0a6efda3c683 285 Gene3D G3DSA:3.40.190.10 26 113 3.4E-24 T 13-09-2016 THL1_RS01740 272ce43ee89a206a7c1b0a6efda3c683 285 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 31 275 1.9E-66 T 13-09-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 THL1_RS01740 272ce43ee89a206a7c1b0a6efda3c683 285 Gene3D G3DSA:3.40.190.100 114 235 6.3E-39 T 13-09-2016 THL1_RS01740 272ce43ee89a206a7c1b0a6efda3c683 285 SUPERFAMILY SSF53850 24 285 1.09E-80 T 13-09-2016 THL1_RS01740 272ce43ee89a206a7c1b0a6efda3c683 285 PANTHER PTHR30177:SF0 11 279 7.3E-85 T 13-09-2016 THL1_RS08545 d8b815c66e1086fd2464366743b1604b 105 Pfam PF10052 Protein of unknown function (DUF2288) 8 97 1.6E-30 T 13-09-2016 IPR018741 Protein of unknown function DUF2288 THL1_RS02240 7ea41817b40d0c8b7ba311b28d5699d7 85 Pfam PF10976 Protein of unknown function (DUF2790) 23 82 1.6E-20 T 13-09-2016 IPR021245 Protein of unknown function DUF2790 THL1_RS19790 6e3dd0ee5432652e5a4ad339585b2b19 465 Pfam PF00324 Amino acid permease 16 437 1.8E-118 T 13-09-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 THL1_RS19790 6e3dd0ee5432652e5a4ad339585b2b19 465 PIRSF PIRSF006060 1 460 6.7E-80 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS19790 6e3dd0ee5432652e5a4ad339585b2b19 465 PANTHER PTHR11785 2 452 7.5E-259 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS19790 6e3dd0ee5432652e5a4ad339585b2b19 465 ProSitePatterns PS00218 Amino acid permeases signature. 41 72 - T 13-09-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 THL1_RS19790 6e3dd0ee5432652e5a4ad339585b2b19 465 PANTHER PTHR11785:SF399 2 452 7.5E-259 T 13-09-2016 THL1_RS09675 35c16cfe86c0107d49d684a4470aff54 505 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 439 3.9E-138 T 13-09-2016 IPR002823 Protein of unknown function DUF112, transmembrane THL1_RS09675 35c16cfe86c0107d49d684a4470aff54 505 PANTHER PTHR35342 2 504 0.0 T 13-09-2016 THL1_RS09675 35c16cfe86c0107d49d684a4470aff54 505 PANTHER PTHR35342:SF1 2 504 0.0 T 13-09-2016 THL1_RS10340 bfafd8f7b604524468f3f88824145024 73 Pfam PF11197 Protein of unknown function (DUF2835) 5 71 2.8E-25 T 13-09-2016 IPR021363 Protein of unknown function DUF2835 THL1_RS23400 09e898659edf8b3eaf811dbf6fe7c648 233 SUPERFAMILY SSF56112 16 216 4.08E-9 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS23400 09e898659edf8b3eaf811dbf6fe7c648 233 PIRSF PIRSF026326 1 233 1.2E-85 T 13-09-2016 IPR027023 Putative lipopolysaccharide kinase InaA THL1_RS23400 09e898659edf8b3eaf811dbf6fe7c648 233 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 19 220 1.1E-45 T 13-09-2016 IPR010440 Lipopolysaccharide kinase GO:0005524|GO:0016020|GO:0016773 THL1_RS26095 d3c00a9e6b7ecca7f15e16f1050b5776 396 Pfam PF04932 O-Antigen ligase 200 325 4.7E-10 T 13-09-2016 IPR007016 O-antigen ligase-related THL1_RS13330 1c16c873fe801a6d84b981846f6378f5 240 SUPERFAMILY SSF52499 25 237 7.33E-34 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS13330 1c16c873fe801a6d84b981846f6378f5 240 Pfam PF00857 Isochorismatase family 33 214 3.0E-26 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS13330 1c16c873fe801a6d84b981846f6378f5 240 Gene3D G3DSA:3.40.50.850 21 238 6.9E-37 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS13330 1c16c873fe801a6d84b981846f6378f5 240 PANTHER PTHR11080 9 239 7.8E-17 T 13-09-2016 THL1_RS18535 20d0cc8df2c109fd87bb3326a6410468 709 Gene3D G3DSA:1.10.443.10 350 524 1.3E-20 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS18535 20d0cc8df2c109fd87bb3326a6410468 709 Pfam PF00589 Phage integrase family 350 519 5.0E-16 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS18535 20d0cc8df2c109fd87bb3326a6410468 709 SUPERFAMILY SSF56349 343 527 1.5E-24 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS12870 501f5a033b537abba42bb54399c332bb 293 PANTHER PTHR11863:SF2 55 250 2.0E-23 T 13-09-2016 THL1_RS12870 501f5a033b537abba42bb54399c332bb 293 PANTHER PTHR11863 55 250 2.0E-23 T 13-09-2016 THL1_RS12870 501f5a033b537abba42bb54399c332bb 293 Pfam PF04116 Fatty acid hydroxylase superfamily 116 249 5.2E-28 T 13-09-2016 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0006633|GO:0016491|GO:0055114 THL1_RS09755 eabe3e1ba0b00bffc026f2eff392ab9f 229 Pfam PF04231 Endonuclease I 22 220 1.6E-40 T 13-09-2016 IPR007346 Endonuclease I GO:0004518 THL1_RS09755 eabe3e1ba0b00bffc026f2eff392ab9f 229 PANTHER PTHR33607 2 219 1.1E-46 T 13-09-2016 THL1_RS09755 eabe3e1ba0b00bffc026f2eff392ab9f 229 SUPERFAMILY SSF54060 20 222 8.24E-86 T 13-09-2016 THL1_RS16550 9134aea0b03ef2fd7aa7e977917db379 259 PANTHER PTHR30413 1 258 1.3E-148 T 13-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THL1_RS16550 9134aea0b03ef2fd7aa7e977917db379 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 179 198 2.8E-8 T 13-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THL1_RS16550 9134aea0b03ef2fd7aa7e977917db379 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 61 83 2.8E-8 T 13-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THL1_RS16550 9134aea0b03ef2fd7aa7e977917db379 259 PRINTS PR00164 ABC-2 type transport system membrane protein signature 199 218 2.8E-8 T 13-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THL1_RS16550 9134aea0b03ef2fd7aa7e977917db379 259 PANTHER PTHR30413:SF2 1 258 1.3E-148 T 13-09-2016 THL1_RS16550 9134aea0b03ef2fd7aa7e977917db379 259 Pfam PF01061 ABC-2 type transporter 13 221 2.5E-38 T 13-09-2016 IPR013525 ABC-2 type transporter GO:0016020 THL1_RS16550 9134aea0b03ef2fd7aa7e977917db379 259 PIRSF PIRSF006648 2 257 2.6E-23 T 13-09-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 THL1_RS26735 c020dc58a0e50d3613b4d9dfaecc226f 251 PANTHER PTHR38834:SF1 1 250 1.0E-115 T 13-09-2016 THL1_RS26735 c020dc58a0e50d3613b4d9dfaecc226f 251 PANTHER PTHR38834 1 250 1.0E-115 T 13-09-2016 THL1_RS26735 c020dc58a0e50d3613b4d9dfaecc226f 251 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 251 4.9E-21 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS26735 c020dc58a0e50d3613b4d9dfaecc226f 251 Gene3D G3DSA:3.40.190.10 212 251 6.5E-11 T 13-09-2016 THL1_RS26735 c020dc58a0e50d3613b4d9dfaecc226f 251 Gene3D G3DSA:3.40.190.10 30 112 6.5E-11 T 13-09-2016 THL1_RS26735 c020dc58a0e50d3613b4d9dfaecc226f 251 SUPERFAMILY SSF53850 30 251 6.97E-36 T 13-09-2016 THL1_RS26735 c020dc58a0e50d3613b4d9dfaecc226f 251 SMART SM00062 28 251 0.0084 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS26735 c020dc58a0e50d3613b4d9dfaecc226f 251 Gene3D G3DSA:3.40.190.10 113 206 9.9E-7 T 13-09-2016 THL1_RS11770 69db4f54617a5a6be50ed6db6975910d 201 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 26 185 4.2E-26 T 13-09-2016 IPR013830 SGNH hydrolase-type esterase domain THL1_RS11770 69db4f54617a5a6be50ed6db6975910d 201 SUPERFAMILY SSF52266 23 200 2.44E-48 T 13-09-2016 IPR013830 SGNH hydrolase-type esterase domain THL1_RS11770 69db4f54617a5a6be50ed6db6975910d 201 PANTHER PTHR30383:SF5 24 198 1.9E-45 T 13-09-2016 THL1_RS11770 69db4f54617a5a6be50ed6db6975910d 201 PANTHER PTHR30383 24 198 1.9E-45 T 13-09-2016 THL1_RS11770 69db4f54617a5a6be50ed6db6975910d 201 Gene3D G3DSA:3.40.50.1110 23 200 2.0E-52 T 13-09-2016 IPR013830 SGNH hydrolase-type esterase domain THL1_RS27290 b549b3232cd34f9b0bcf6b4c5864fb43 135 PANTHER PTHR35091:SF1 28 134 2.3E-37 T 13-09-2016 THL1_RS27290 b549b3232cd34f9b0bcf6b4c5864fb43 135 Pfam PF03748 Flagellar basal body-associated protein FliL 33 134 2.0E-21 T 13-09-2016 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 THL1_RS27290 b549b3232cd34f9b0bcf6b4c5864fb43 135 PANTHER PTHR35091 28 134 2.3E-37 T 13-09-2016 THL1_RS04455 cc0daae93daa3319caef5fcde69f3690 277 SUPERFAMILY SSF111364 23 276 1.57E-40 T 13-09-2016 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 THL1_RS04455 cc0daae93daa3319caef5fcde69f3690 277 Gene3D G3DSA:2.40.230.20 19 262 7.7E-19 T 13-09-2016 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 THL1_RS15105 795f1ed14c882d14a9541092a28c5597 216 Gene3D G3DSA:3.40.50.300 8 101 6.2E-8 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15105 795f1ed14c882d14a9541092a28c5597 216 Pfam PF05707 Zonular occludens toxin (Zot) 3 99 2.2E-9 T 13-09-2016 IPR008900 Zona occludens toxin THL1_RS06155 9eb83d128135ed210e2dc2217d6154ec 245 SUPERFAMILY SSF48452 82 220 3.32E-14 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS06155 9eb83d128135ed210e2dc2217d6154ec 245 Gene3D G3DSA:1.25.40.10 82 220 7.7E-14 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS16220 cdb8aba10ddee24b6563c30790e81c43 335 Pfam PF05954 Phage late control gene D protein (GPD) 40 313 3.5E-26 T 13-09-2016 THL1_RS16220 cdb8aba10ddee24b6563c30790e81c43 335 SUPERFAMILY SSF69279 6 179 9.07E-29 T 13-09-2016 THL1_RS27405 9b9d4bf2b37e6934f43a41f2465593f2 154 Pfam PF09523 Protein of unknown function (DUF2390) 4 110 1.1E-34 T 13-09-2016 IPR012659 Conserved hypothetical protein CHP02444 THL1_RS27405 9b9d4bf2b37e6934f43a41f2465593f2 154 TIGRFAM TIGR02444 TIGR02444: TIGR02444 family protein 3 113 4.3E-36 T 13-09-2016 IPR012659 Conserved hypothetical protein CHP02444 THL1_RS02440 5f16d492a189b45f8bb7fb46188ef3af 328 PANTHER PTHR21240 1 328 7.5E-78 T 13-09-2016 THL1_RS02440 5f16d492a189b45f8bb7fb46188ef3af 328 SUPERFAMILY SSF51556 1 328 7.66E-75 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS02440 5f16d492a189b45f8bb7fb46188ef3af 328 PANTHER PTHR21240:SF3 1 328 7.5E-78 T 13-09-2016 IPR032465 Amino-carboxymuconate-semialdehyde decarboxylase GO:0001760|GO:0006568|GO:1904984 KEGG: 00380+4.1.1.45|MetaCyc: PWY-5647|MetaCyc: PWY-5652|MetaCyc: PWY-5654|UniPathway: UPA00270 THL1_RS02440 5f16d492a189b45f8bb7fb46188ef3af 328 Gene3D G3DSA:3.20.20.140 1 328 7.5E-76 T 13-09-2016 THL1_RS02440 5f16d492a189b45f8bb7fb46188ef3af 328 Pfam PF04909 Amidohydrolase 3 328 1.1E-41 T 13-09-2016 IPR006680 Amidohydrolase-related GO:0016787 THL1_RS17295 69c84cad991d7c53042a61b5c665a1b2 113 Pfam PF04956 TrbC/VIRB2 family 10 102 2.0E-23 T 13-09-2016 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 THL1_RS02110 f84a2857e40781384757e077fd73db2f 234 PANTHER PTHR30231 2 227 1.4E-28 T 13-09-2016 THL1_RS02110 f84a2857e40781384757e077fd73db2f 234 Gene3D G3DSA:3.30.420.10 33 209 9.9E-35 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS02110 f84a2857e40781384757e077fd73db2f 234 SMART SM00479 39 209 6.1E-13 T 13-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III THL1_RS02110 f84a2857e40781384757e077fd73db2f 234 Pfam PF00929 Exonuclease 41 199 3.8E-14 T 13-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III THL1_RS02110 f84a2857e40781384757e077fd73db2f 234 SUPERFAMILY SSF53098 32 210 8.02E-38 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS23880 883a54584a01d2783d0639a0138a6868 425 Pfam PF00860 Permease family 12 380 1.5E-90 T 13-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS23880 883a54584a01d2783d0639a0138a6868 425 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 327 347 - T 13-09-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 THL1_RS23880 883a54584a01d2783d0639a0138a6868 425 PANTHER PTHR11119 8 409 5.7E-167 T 13-09-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 THL1_RS23880 883a54584a01d2783d0639a0138a6868 425 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 10 407 2.0E-108 T 13-09-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 THL1_RS23880 883a54584a01d2783d0639a0138a6868 425 PANTHER PTHR11119:SF49 8 409 5.7E-167 T 13-09-2016 THL1_RS03795 56fa4df577cb9cd18a79689e2a1d1ef4 172 Pfam PF11736 Protein of unknown function (DUF3299) 24 167 1.5E-49 T 13-09-2016 IPR021727 Protein of unknown function DUF3299 THL1_RS27525 51415b3fb255c6f552fd59aae83db843 141 SUPERFAMILY SSF111038 1 139 3.92E-45 T 13-09-2016 IPR001602 Uncharacterised protein family UPF0047 THL1_RS27525 51415b3fb255c6f552fd59aae83db843 141 Gene3D G3DSA:2.60.120.460 1 139 1.4E-51 T 13-09-2016 IPR001602 Uncharacterised protein family UPF0047 THL1_RS27525 51415b3fb255c6f552fd59aae83db843 141 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 9 139 4.6E-39 T 13-09-2016 IPR001602 Uncharacterised protein family UPF0047 THL1_RS27525 51415b3fb255c6f552fd59aae83db843 141 PIRSF PIRSF004681 1 139 2.1E-42 T 13-09-2016 IPR001602 Uncharacterised protein family UPF0047 THL1_RS27525 51415b3fb255c6f552fd59aae83db843 141 PANTHER PTHR30615 1 141 7.2E-70 T 13-09-2016 THL1_RS27525 51415b3fb255c6f552fd59aae83db843 141 Pfam PF01894 Uncharacterised protein family UPF0047 19 135 9.3E-35 T 13-09-2016 IPR001602 Uncharacterised protein family UPF0047 THL1_RS07530 cc49789b56b9eca83619735a1c224c73 228 Gene3D G3DSA:3.40.50.850 3 197 6.6E-58 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS07530 cc49789b56b9eca83619735a1c224c73 228 SUPERFAMILY SSF52499 4 186 2.49E-55 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS07530 cc49789b56b9eca83619735a1c224c73 228 PANTHER PTHR11080 6 171 4.7E-45 T 13-09-2016 THL1_RS07530 cc49789b56b9eca83619735a1c224c73 228 Pfam PF00857 Isochorismatase family 6 168 3.2E-42 T 13-09-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 THL1_RS02395 fd7801b7d21d353a9663fccdbfd4a1b3 75 Pfam PF16694 Cytochrome P460 5 71 1.3E-17 T 13-09-2016 IPR032033 Cytochrome P460 THL1_RS10440 0a77eb048c4b2ff1ba1d258b491b1b09 316 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 37 241 1.5E-24 T 13-09-2016 IPR000477 Reverse transcriptase domain THL1_RS10440 0a77eb048c4b2ff1ba1d258b491b1b09 316 SUPERFAMILY SSF56672 30 241 2.74E-8 T 13-09-2016 THL1_RS10440 0a77eb048c4b2ff1ba1d258b491b1b09 316 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 149 162 2.1E-26 T 13-09-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THL1_RS10440 0a77eb048c4b2ff1ba1d258b491b1b09 316 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 93 111 2.1E-26 T 13-09-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THL1_RS10440 0a77eb048c4b2ff1ba1d258b491b1b09 316 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 77 91 2.1E-26 T 13-09-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THL1_RS10440 0a77eb048c4b2ff1ba1d258b491b1b09 316 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 46 58 2.1E-26 T 13-09-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THL1_RS10440 0a77eb048c4b2ff1ba1d258b491b1b09 316 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 237 243 2.1E-26 T 13-09-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THL1_RS10440 0a77eb048c4b2ff1ba1d258b491b1b09 316 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 32 45 2.1E-26 T 13-09-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THL1_RS10440 0a77eb048c4b2ff1ba1d258b491b1b09 316 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 182 193 2.1E-26 T 13-09-2016 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THL1_RS16680 a29faa315a084dc99fbd58d20027a410 85 SUPERFAMILY SSF52833 2 76 1.73E-10 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS16680 a29faa315a084dc99fbd58d20027a410 85 Gene3D G3DSA:3.40.30.10 1 78 4.2E-12 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS16680 a29faa315a084dc99fbd58d20027a410 85 Pfam PF13192 Thioredoxin domain 1 76 1.2E-10 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS07930 64d26fadbb6dcf61b7d8865406537935 240 PANTHER PTHR24220 3 239 1.7E-151 T 13-09-2016 THL1_RS07930 64d26fadbb6dcf61b7d8865406537935 240 PIRSF PIRSF039085 1 240 1.6E-106 T 13-09-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 THL1_RS07930 64d26fadbb6dcf61b7d8865406537935 240 Gene3D G3DSA:3.40.50.300 1 237 7.8E-84 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07930 64d26fadbb6dcf61b7d8865406537935 240 PANTHER PTHR24220:SF569 3 239 1.7E-151 T 13-09-2016 THL1_RS07930 64d26fadbb6dcf61b7d8865406537935 240 Pfam PF00005 ABC transporter 17 165 2.0E-35 T 13-09-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THL1_RS07930 64d26fadbb6dcf61b7d8865406537935 240 SMART SM00382 26 213 2.3E-17 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS07930 64d26fadbb6dcf61b7d8865406537935 240 SUPERFAMILY SSF52540 1 235 2.18E-79 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS07930 64d26fadbb6dcf61b7d8865406537935 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 13-09-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THL1_RS18960 f2e6d0fd3eae2826ddd4ac33d97b674a 248 SUPERFAMILY SSF161098 24 223 2.09E-42 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS18960 f2e6d0fd3eae2826ddd4ac33d97b674a 248 Gene3D G3DSA:1.10.3720.10 23 237 1.1E-47 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS18960 f2e6d0fd3eae2826ddd4ac33d97b674a 248 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 238 3.4E-25 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS18960 f2e6d0fd3eae2826ddd4ac33d97b674a 248 PANTHER PTHR30085:SF4 1 244 2.3E-140 T 13-09-2016 IPR030202 Glutamate/aspartate transport system permease protein GltJ/AatQ GO:0006865|GO:0016021|GO:0043190 THL1_RS18960 f2e6d0fd3eae2826ddd4ac33d97b674a 248 PANTHER PTHR30085 1 244 2.3E-140 T 13-09-2016 THL1_RS18960 f2e6d0fd3eae2826ddd4ac33d97b674a 248 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 24 131 7.0E-19 T 13-09-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 THL1_RS00665 46efaa62615ade3717e43ea0df0b1b88 357 Pfam PF00487 Fatty acid desaturase 69 331 2.4E-15 T 13-09-2016 IPR005804 Fatty acid desaturase domain GO:0006629 THL1_RS10905 018f22884ab42d35b84000967557ad2b 361 Gene3D G3DSA:3.40.50.1820 54 321 2.3E-27 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS10905 018f22884ab42d35b84000967557ad2b 361 SUPERFAMILY SSF53474 53 321 2.17E-28 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS10905 018f22884ab42d35b84000967557ad2b 361 PANTHER PTHR10992 2 321 2.3E-12 T 13-09-2016 THL1_RS11200 d6058bd8bbf0d3a7700fb1993976c9f6 276 PANTHER PTHR10587 42 183 1.3E-24 T 13-09-2016 THL1_RS11200 d6058bd8bbf0d3a7700fb1993976c9f6 276 SUPERFAMILY SSF88713 2 266 3.34E-52 T 13-09-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THL1_RS11200 d6058bd8bbf0d3a7700fb1993976c9f6 276 Gene3D G3DSA:3.20.20.370 3 266 2.3E-68 T 13-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 THL1_RS11200 d6058bd8bbf0d3a7700fb1993976c9f6 276 Pfam PF01522 Polysaccharide deacetylase 45 150 3.1E-17 T 13-09-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 THL1_RS08205 70e5eef5be5159658d07217fb12e20a0 154 PANTHER PTHR35603:SF1 2 153 3.1E-46 T 13-09-2016 THL1_RS08205 70e5eef5be5159658d07217fb12e20a0 154 PANTHER PTHR35603 2 153 3.1E-46 T 13-09-2016 THL1_RS09190 ee017b75eb0ddb71608557e4c0562067 392 Pfam PF05762 VWA domain containing CoxE-like protein 186 272 6.6E-10 T 13-09-2016 IPR008912 Uncharacterised protein family CoxE-like THL1_RS26100 0d8f3f45efadce9d3ab42c11a5e4e97a 228 Gene3D G3DSA:1.10.510.10 106 181 2.0E-5 T 13-09-2016 THL1_RS26100 0d8f3f45efadce9d3ab42c11a5e4e97a 228 SUPERFAMILY SSF56112 27 191 5.2E-15 T 13-09-2016 IPR011009 Protein kinase-like domain THL1_RS26100 0d8f3f45efadce9d3ab42c11a5e4e97a 228 Pfam PF01636 Phosphotransferase enzyme family 50 127 2.1E-6 T 13-09-2016 IPR002575 Aminoglycoside phosphotransferase THL1_RS28090 ba481e69303cf4927bc04f9c02d6ca41 81 PANTHER PTHR33884:SF1 1 81 3.2E-30 T 13-09-2016 THL1_RS28090 ba481e69303cf4927bc04f9c02d6ca41 81 Pfam PF04226 Transglycosylase associated protein 34 80 1.6E-12 T 13-09-2016 IPR007341 Transglycosylase-associated protein GO:0016021 THL1_RS28090 ba481e69303cf4927bc04f9c02d6ca41 81 PANTHER PTHR33884 1 81 3.2E-30 T 13-09-2016 THL1_RS24615 8a321e0a97068f1acd2036215d3afebf 71 Gene3D G3DSA:1.10.1470.10 7 67 1.4E-14 T 13-09-2016 IPR008462 CsbD-like THL1_RS24615 8a321e0a97068f1acd2036215d3afebf 71 SUPERFAMILY SSF69047 7 68 3.14E-12 T 13-09-2016 IPR008462 CsbD-like THL1_RS18615 8a5ab78c7281a26bbfc0fec0d3c8dd58 425 Gene3D G3DSA:2.40.10.10 13 74 1.1E-6 T 13-09-2016 THL1_RS18615 8a5ab78c7281a26bbfc0fec0d3c8dd58 425 SUPERFAMILY SSF50494 16 193 4.42E-13 T 13-09-2016 IPR009003 Peptidase S1, PA clan THL1_RS23835 d32bbe7fe820c47cc8c661cc9ae4a3f6 193 Pfam PF03923 Uncharacterized lipoprotein 36 191 3.2E-11 T 13-09-2016 IPR005619 Uncharacterised protein family, YajG THL1_RS16715 116ef417a69ed42859167fcb00b61d26 314 SMART SM00382 41 204 0.0033 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS16715 116ef417a69ed42859167fcb00b61d26 314 Pfam PF05621 Bacterial TniB protein 15 253 3.9E-19 T 13-09-2016 IPR008868 Bacterial TniB THL1_RS16715 116ef417a69ed42859167fcb00b61d26 314 Gene3D G3DSA:3.40.50.300 47 172 1.9E-9 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16715 116ef417a69ed42859167fcb00b61d26 314 SUPERFAMILY SSF52540 40 209 5.51E-17 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24125 3afdc4caf78bd0e199a8b34136fb0cb6 763 PANTHER PTHR30462 1 761 6.1E-285 T 13-09-2016 THL1_RS24125 3afdc4caf78bd0e199a8b34136fb0cb6 763 PANTHER PTHR30462:SF0 1 761 6.1E-285 T 13-09-2016 THL1_RS24125 3afdc4caf78bd0e199a8b34136fb0cb6 763 Pfam PF02470 MlaD protein 158 241 3.6E-10 T 13-09-2016 IPR003399 Mce/MlaD THL1_RS24125 3afdc4caf78bd0e199a8b34136fb0cb6 763 Pfam PF02470 MlaD protein 518 603 5.7E-11 T 13-09-2016 IPR003399 Mce/MlaD THL1_RS24125 3afdc4caf78bd0e199a8b34136fb0cb6 763 Pfam PF02470 MlaD protein 41 131 4.2E-11 T 13-09-2016 IPR003399 Mce/MlaD THL1_RS24125 3afdc4caf78bd0e199a8b34136fb0cb6 763 Pfam PF02470 MlaD protein 394 462 1.4E-8 T 13-09-2016 IPR003399 Mce/MlaD THL1_RS24125 3afdc4caf78bd0e199a8b34136fb0cb6 763 Pfam PF02470 MlaD protein 279 368 1.4E-11 T 13-09-2016 IPR003399 Mce/MlaD THL1_RS23495 d99171763f4a13c5195682d8d3053da9 163 Pfam PF06146 Phosphate-starvation-inducible E 60 127 4.8E-18 T 13-09-2016 IPR020948 Phosphate-starvation-induced PsiE-like THL1_RS23495 d99171763f4a13c5195682d8d3053da9 163 PANTHER PTHR37819 10 149 1.1E-40 T 13-09-2016 THL1_RS23495 d99171763f4a13c5195682d8d3053da9 163 PIRSF PIRSF029598 2 145 1.7E-43 T 13-09-2016 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 THL1_RS23495 d99171763f4a13c5195682d8d3053da9 163 PANTHER PTHR37819:SF1 10 149 1.1E-40 T 13-09-2016 THL1_RS24780 e600a42b2842bec6ff6d2bf4e18bba3c 183 Gene3D G3DSA:3.30.70.60 86 181 2.5E-4 T 13-09-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 THL1_RS24780 e600a42b2842bec6ff6d2bf4e18bba3c 183 Pfam PF10741 Type II secretion system (T2SS), protein M subtype b 83 181 3.5E-7 T 13-09-2016 IPR007690 Type II secretion system, protein M GO:0006858 THL1_RS14540 22d17740265d2d6b5f95ee40098bbb90 77 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 13-09-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site THL1_RS14540 22d17740265d2d6b5f95ee40098bbb90 77 SUPERFAMILY SSF51230 8 77 2.22E-15 T 13-09-2016 IPR011053 Single hybrid motif THL1_RS14540 22d17740265d2d6b5f95ee40098bbb90 77 Pfam PF00364 Biotin-requiring enzyme 16 74 5.3E-12 T 13-09-2016 IPR000089 Biotin/lipoyl attachment THL1_RS14540 22d17740265d2d6b5f95ee40098bbb90 77 Gene3D G3DSA:2.40.50.100 10 76 1.1E-15 T 13-09-2016 THL1_RS25050 ecd494c8dea9aafff6f755bfba70ce11 177 SUPERFAMILY SSF81342 3 174 1.96E-31 T 13-09-2016 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 THL1_RS25050 ecd494c8dea9aafff6f755bfba70ce11 177 Gene3D G3DSA:1.20.950.20 36 172 5.0E-7 T 13-09-2016 THL1_RS25050 ecd494c8dea9aafff6f755bfba70ce11 177 Pfam PF01292 Prokaryotic cytochrome b561 9 170 6.3E-19 T 13-09-2016 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THL1_RS00370 89363f363f7c705a75ad13375fd1977b 213 PANTHER PTHR11649 16 193 5.3E-50 T 13-09-2016 THL1_RS00370 89363f363f7c705a75ad13375fd1977b 213 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 14 198 9.1E-70 T 13-09-2016 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0000917|GO:0005525 THL1_RS00370 89363f363f7c705a75ad13375fd1977b 213 Pfam PF01926 50S ribosome-binding GTPase 33 150 2.5E-17 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS00370 89363f363f7c705a75ad13375fd1977b 213 SUPERFAMILY SSF52540 23 203 5.1E-32 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS00370 89363f363f7c705a75ad13375fd1977b 213 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 19 202 26.669 T 13-09-2016 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0000917|GO:0005525 THL1_RS00370 89363f363f7c705a75ad13375fd1977b 213 Gene3D G3DSA:3.40.50.300 12 202 2.0E-37 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS24860 217c113248bc53ed8d019bebc3dfef95 432 PANTHER PTHR15498 40 277 2.4E-38 T 13-09-2016 THL1_RS24860 217c113248bc53ed8d019bebc3dfef95 432 PANTHER PTHR15498:SF49 40 277 2.4E-38 T 13-09-2016 THL1_RS01685 13993e3473f686aa4e806a61b564ca39 77 Pfam PF06568 Domain of unknown function (DUF1127) 34 66 3.4E-10 T 13-09-2016 IPR009506 Protein of unknown function DUF1127 THL1_RS02790 9646731f40e8af47cd81a7338e79ab2c 581 Pfam PF02538 Hydantoinase B/oxoprolinase 5 533 7.6E-142 T 13-09-2016 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 THL1_RS02790 9646731f40e8af47cd81a7338e79ab2c 581 PANTHER PTHR11365 4 538 4.2E-53 T 13-09-2016 THL1_RS01035 feb87bc06400adc5cafeeab7a93c6c30 458 Pfam PF11981 Domain of unknown function (DUF3482) 165 451 2.6E-110 T 13-09-2016 IPR021871 Protein of unknown function DUF3482 THL1_RS01035 feb87bc06400adc5cafeeab7a93c6c30 458 PANTHER PTHR11649 4 99 9.6E-15 T 13-09-2016 THL1_RS01035 feb87bc06400adc5cafeeab7a93c6c30 458 PANTHER PTHR11649 116 152 9.6E-15 T 13-09-2016 THL1_RS01035 feb87bc06400adc5cafeeab7a93c6c30 458 Gene3D G3DSA:3.40.50.300 3 77 3.9E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01035 feb87bc06400adc5cafeeab7a93c6c30 458 Gene3D G3DSA:3.40.50.300 109 154 3.9E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01035 feb87bc06400adc5cafeeab7a93c6c30 458 SUPERFAMILY SSF52540 3 72 8.3E-19 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01035 feb87bc06400adc5cafeeab7a93c6c30 458 SUPERFAMILY SSF52540 111 162 8.3E-19 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS01035 feb87bc06400adc5cafeeab7a93c6c30 458 Pfam PF01926 50S ribosome-binding GTPase 7 152 6.2E-17 T 13-09-2016 IPR006073 GTP binding domain GO:0005525 THL1_RS24655 fee34d528eaf6c1218a59b8d842b3de0 277 SMART SM00749 38 101 1.0 T 13-09-2016 IPR014004 Transport-associated and nodulation domain, bacteria THL1_RS24655 fee34d528eaf6c1218a59b8d842b3de0 277 SMART SM00749 126 189 0.011 T 13-09-2016 IPR014004 Transport-associated and nodulation domain, bacteria THL1_RS24655 fee34d528eaf6c1218a59b8d842b3de0 277 SMART SM00749 215 276 0.098 T 13-09-2016 IPR014004 Transport-associated and nodulation domain, bacteria THL1_RS24655 fee34d528eaf6c1218a59b8d842b3de0 277 PANTHER PTHR34606 20 276 9.3E-67 T 13-09-2016 THL1_RS24655 fee34d528eaf6c1218a59b8d842b3de0 277 Pfam PF04972 BON domain 34 100 3.8E-15 T 13-09-2016 IPR007055 BON domain THL1_RS24655 fee34d528eaf6c1218a59b8d842b3de0 277 Pfam PF04972 BON domain 211 272 1.4E-16 T 13-09-2016 IPR007055 BON domain THL1_RS24655 fee34d528eaf6c1218a59b8d842b3de0 277 Pfam PF04972 BON domain 122 188 4.5E-12 T 13-09-2016 IPR007055 BON domain THL1_RS24655 fee34d528eaf6c1218a59b8d842b3de0 277 PANTHER PTHR34606:SF3 20 276 9.3E-67 T 13-09-2016 THL1_RS19285 5c2091ef83adb5ea9dedd881d3c4236f 136 PANTHER PTHR38102 2 136 5.3E-17 T 13-09-2016 THL1_RS08040 25446bdb6c42f51d79874632cd6ba12f 502 Pfam PF05226 CHASE2 domain 49 330 2.5E-9 T 13-09-2016 IPR007890 CHASE2 THL1_RS21400 64ce6a3693557f938f520be33edda1dd 286 PIRSF PIRSF028200 7 285 2.4E-73 T 13-09-2016 IPR016875 Uncharacterised conserved protein UCP028200 THL1_RS19990 fffdabd846fbc03460fa0cb9b688f357 210 PANTHER PTHR11260:SF289 1 207 2.3E-78 T 13-09-2016 THL1_RS19990 fffdabd846fbc03460fa0cb9b688f357 210 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 3 208 1.8E-82 T 13-09-2016 IPR005955 Maleylacetoacetate isomerase GO:0003824|GO:0005737|GO:0009072 THL1_RS19990 fffdabd846fbc03460fa0cb9b688f357 210 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 82 8.9E-19 T 13-09-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THL1_RS19990 fffdabd846fbc03460fa0cb9b688f357 210 Gene3D G3DSA:1.20.1050.10 92 208 2.9E-41 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS19990 fffdabd846fbc03460fa0cb9b688f357 210 Gene3D G3DSA:3.40.30.10 1 91 2.9E-31 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS19990 fffdabd846fbc03460fa0cb9b688f357 210 SUPERFAMILY SSF47616 84 209 4.35E-28 T 13-09-2016 IPR010987 Glutathione S-transferase, C-terminal-like THL1_RS19990 fffdabd846fbc03460fa0cb9b688f357 210 PANTHER PTHR11260 1 207 2.3E-78 T 13-09-2016 THL1_RS19990 fffdabd846fbc03460fa0cb9b688f357 210 SUPERFAMILY SSF52833 1 92 2.2E-24 T 13-09-2016 IPR012336 Thioredoxin-like fold THL1_RS10240 74a17c0d4c8ad96f0bbd3ef745cfecaa 755 PANTHER PTHR15498 37 280 1.0E-25 T 13-09-2016 THL1_RS10240 74a17c0d4c8ad96f0bbd3ef745cfecaa 755 PANTHER PTHR15498:SF49 37 280 1.0E-25 T 13-09-2016 THL1_RS14130 068233970bf79a4548077ed035be3f9c 392 Pfam PF13609 Gram-negative porin 16 371 8.4E-33 T 13-09-2016 THL1_RS14130 068233970bf79a4548077ed035be3f9c 392 SUPERFAMILY SSF56935 32 391 3.36E-37 T 13-09-2016 THL1_RS14130 068233970bf79a4548077ed035be3f9c 392 Gene3D G3DSA:2.40.160.10 33 391 4.2E-14 T 13-09-2016 IPR023614 Porin domain THL1_RS25245 6f67b12085f43d1f850b79a94da84e31 217 Pfam PF11153 Protein of unknown function (DUF2931) 8 215 9.0E-35 T 13-09-2016 IPR021326 Protein of unknown function DUF2931 THL1_RS19370 80a86a619feb17955f20a97816055c91 218 Pfam PF03576 Peptidase family S58 46 196 5.5E-43 T 13-09-2016 IPR005321 Peptidase S58, DmpA THL1_RS19370 80a86a619feb17955f20a97816055c91 218 PANTHER PTHR36512 46 212 1.1E-73 T 13-09-2016 THL1_RS19370 80a86a619feb17955f20a97816055c91 218 PANTHER PTHR36512:SF1 46 212 1.1E-73 T 13-09-2016 THL1_RS19370 80a86a619feb17955f20a97816055c91 218 Gene3D G3DSA:3.60.70.12 1 38 2.4E-9 T 13-09-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 THL1_RS19370 80a86a619feb17955f20a97816055c91 218 Gene3D G3DSA:3.60.70.12 46 210 1.7E-48 T 13-09-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 THL1_RS19370 80a86a619feb17955f20a97816055c91 218 SUPERFAMILY SSF56266 1 210 6.67E-55 T 13-09-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 THL1_RS26485 cd0cb67beea4e47bdee134aa0a2f2a28 145 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 8.9E-51 T 13-09-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 THL1_RS26485 cd0cb67beea4e47bdee134aa0a2f2a28 145 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 5.3E-57 T 13-09-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 THL1_RS26485 cd0cb67beea4e47bdee134aa0a2f2a28 145 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 34.262 T 13-09-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 THL1_RS26485 cd0cb67beea4e47bdee134aa0a2f2a28 145 Gene3D G3DSA:3.50.80.10 1 145 9.9E-55 T 13-09-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain THL1_RS26485 cd0cb67beea4e47bdee134aa0a2f2a28 145 SUPERFAMILY SSF69500 1 144 3.53E-53 T 13-09-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain THL1_RS26485 cd0cb67beea4e47bdee134aa0a2f2a28 145 PANTHER PTHR10472 2 145 1.6E-64 T 13-09-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 THL1_RS20745 95ba56e9baed1082a37b76e189fe17f0 308 SUPERFAMILY SSF53098 1 104 2.91E-13 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS20745 95ba56e9baed1082a37b76e189fe17f0 308 Gene3D G3DSA:3.30.420.10 1 103 2.1E-14 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS03955 48ac448df06072de026385852fd8904b 132 Pfam PF04892 VanZ like family 47 111 6.7E-8 T 13-09-2016 IPR006976 VanZ-like THL1_RS03955 48ac448df06072de026385852fd8904b 132 SUPERFAMILY SSF144091 50 116 1.96E-5 T 13-09-2016 THL1_RS01780 b69df2d0f421bd78ea468ecc1f8c45ff 259 Gene3D G3DSA:3.40.50.620 28 257 6.6E-26 T 13-09-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THL1_RS01780 b69df2d0f421bd78ea468ecc1f8c45ff 259 Pfam PF01012 Electron transfer flavoprotein domain 28 186 8.4E-15 T 13-09-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 THL1_RS01780 b69df2d0f421bd78ea468ecc1f8c45ff 259 SMART SM00893 14 192 1.7E-8 T 13-09-2016 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: REACT_6305 THL1_RS01780 b69df2d0f421bd78ea468ecc1f8c45ff 259 SUPERFAMILY SSF52402 26 219 9.57E-25 T 13-09-2016 THL1_RS01780 b69df2d0f421bd78ea468ecc1f8c45ff 259 PANTHER PTHR21294 29 169 3.1E-20 T 13-09-2016 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 THL1_RS09835 ca8dfd3793013dbb00eaaa500f92cebd 201 Pfam PF13579 Glycosyl transferase 4-like domain 23 199 6.8E-8 T 13-09-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain THL1_RS09835 ca8dfd3793013dbb00eaaa500f92cebd 201 SUPERFAMILY SSF53756 29 198 5.86E-7 T 13-09-2016 THL1_RS21080 a2d4ff130a078758e19fd56fab246f16 66 Pfam PF12728 Helix-turn-helix domain 13 59 5.4E-8 T 13-09-2016 THL1_RS18905 b403088e3da8933beb54ecf28492fd86 209 Pfam PF11153 Protein of unknown function (DUF2931) 4 207 5.4E-41 T 13-09-2016 IPR021326 Protein of unknown function DUF2931 THL1_RS01015 327d00ae828f2cb16f133985bdd350b6 267 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 138 150 - T 13-09-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 THL1_RS01015 327d00ae828f2cb16f133985bdd350b6 267 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 255 1.4E-81 T 13-09-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 THL1_RS01015 327d00ae828f2cb16f133985bdd350b6 267 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 3 261 5.7E-87 T 13-09-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 THL1_RS01015 327d00ae828f2cb16f133985bdd350b6 267 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 260 20.031 T 13-09-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 THL1_RS01015 327d00ae828f2cb16f133985bdd350b6 267 PANTHER PTHR30589:SF0 1 263 1.2E-113 T 13-09-2016 THL1_RS01015 327d00ae828f2cb16f133985bdd350b6 267 PANTHER PTHR30589 1 263 1.2E-113 T 13-09-2016 THL1_RS10255 650f66e93c8d3733e644bb2034d70668 324 SUPERFAMILY SSF56300 9 174 1.22E-31 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS10255 650f66e93c8d3733e644bb2034d70668 324 SUPERFAMILY SSF56300 246 303 1.22E-31 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS10255 650f66e93c8d3733e644bb2034d70668 324 PANTHER PTHR11668:SF281 9 86 1.1E-24 T 13-09-2016 THL1_RS10255 650f66e93c8d3733e644bb2034d70668 324 Pfam PF00149 Calcineurin-like phosphoesterase 11 145 1.3E-10 T 13-09-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 THL1_RS10255 650f66e93c8d3733e644bb2034d70668 324 Gene3D G3DSA:3.60.21.10 215 309 1.3E-40 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS10255 650f66e93c8d3733e644bb2034d70668 324 Gene3D G3DSA:3.60.21.10 3 174 1.3E-40 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS10255 650f66e93c8d3733e644bb2034d70668 324 PANTHER PTHR11668 9 86 1.1E-24 T 13-09-2016 THL1_RS11115 e18d1cc40077047dbc78c09b3598294a 108 Gene3D G3DSA:3.10.450.50 12 105 7.0E-6 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS11115 e18d1cc40077047dbc78c09b3598294a 108 Pfam PF12680 SnoaL-like domain 19 103 1.3E-6 T 13-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain THL1_RS11115 e18d1cc40077047dbc78c09b3598294a 108 SUPERFAMILY SSF54427 5 106 4.97E-10 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS14420 b772f44b0549021a9ae00bbcdc7ad96e 419 PANTHER PTHR34596 1 419 2.6E-151 T 13-09-2016 THL1_RS14420 b772f44b0549021a9ae00bbcdc7ad96e 419 Gene3D G3DSA:2.40.160.10 31 419 1.0E-145 T 13-09-2016 IPR023614 Porin domain THL1_RS14420 b772f44b0549021a9ae00bbcdc7ad96e 419 Pfam PF03573 outer membrane porin, OprD family 26 417 1.6E-152 T 13-09-2016 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 THL1_RS25510 d213d10d276c54058bedc94f5ff75a10 359 SUPERFAMILY SSF110296 7 344 1.02E-60 T 13-09-2016 THL1_RS25510 d213d10d276c54058bedc94f5ff75a10 359 Gene3D G3DSA:2.130.10.10 7 353 6.5E-79 T 13-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THL1_RS12835 6ebd8dbf6ddffc718209f00fd55da405 84 Pfam PF11666 Protein of unknown function (DUF2933) 25 74 4.4E-19 T 13-09-2016 IPR021682 Protein of unknown function DUF2933 THL1_RS21590 9c42af00e8cb95ac8b1115a46c2b463d 72 PANTHER PTHR37424:SF1 2 72 9.7E-17 T 13-09-2016 THL1_RS21590 9c42af00e8cb95ac8b1115a46c2b463d 72 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 50 1.4E-10 T 13-09-2016 IPR007419 BFD-like [2Fe-2S]-binding domain THL1_RS21590 9c42af00e8cb95ac8b1115a46c2b463d 72 PANTHER PTHR37424 2 72 9.7E-17 T 13-09-2016 THL1_RS21905 5d6f1027e949af3f22e6b448319afb11 293 PANTHER PTHR39456:SF1 6 291 1.2E-136 T 13-09-2016 THL1_RS21905 5d6f1027e949af3f22e6b448319afb11 293 Pfam PF10118 Predicted metal-dependent hydrolase 9 268 6.8E-69 T 13-09-2016 IPR016516 Uncharacterised conserved protein UCP07580 THL1_RS21905 5d6f1027e949af3f22e6b448319afb11 293 PIRSF PIRSF007580 2 288 1.5E-101 T 13-09-2016 IPR016516 Uncharacterised conserved protein UCP07580 THL1_RS21905 5d6f1027e949af3f22e6b448319afb11 293 PANTHER PTHR39456 6 291 1.2E-136 T 13-09-2016 THL1_RS00485 133473ea0fc1ae7ef0ecff0eb66935c5 106 Pfam PF09498 Protein of unknown function (DUF2388) 36 105 1.4E-29 T 13-09-2016 IPR012661 Conserved hypothetical protein CHP02448 THL1_RS00485 133473ea0fc1ae7ef0ecff0eb66935c5 106 TIGRFAM TIGR02448 TIGR02448: conserverd hypothetical protein 1 105 1.3E-31 T 13-09-2016 IPR012661 Conserved hypothetical protein CHP02448 THL1_RS25115 860d5bed6c7402c971202ff638c285b9 300 SUPERFAMILY SSF103481 187 283 1.44E-13 T 13-09-2016 THL1_RS25115 860d5bed6c7402c971202ff638c285b9 300 Pfam PF00892 EamA-like transporter family 6 130 1.1E-17 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS25115 860d5bed6c7402c971202ff638c285b9 300 Pfam PF00892 EamA-like transporter family 142 280 1.1E-15 T 13-09-2016 IPR000620 EamA domain GO:0016020|GO:0016021 THL1_RS25115 860d5bed6c7402c971202ff638c285b9 300 PANTHER PTHR32322:SF9 5 283 1.2E-104 T 13-09-2016 THL1_RS25115 860d5bed6c7402c971202ff638c285b9 300 PANTHER PTHR32322 5 283 1.2E-104 T 13-09-2016 THL1_RS25115 860d5bed6c7402c971202ff638c285b9 300 SUPERFAMILY SSF103481 38 134 1.7E-12 T 13-09-2016 THL1_RS18070 1d4a64758c779160d8721e601036a099 69 PANTHER PTHR37011 1 69 4.3E-22 T 13-09-2016 THL1_RS18070 1d4a64758c779160d8721e601036a099 69 PANTHER PTHR37011:SF1 1 69 4.3E-22 T 13-09-2016 THL1_RS18070 1d4a64758c779160d8721e601036a099 69 Gene3D G3DSA:2.30.30.100 16 69 1.0E-23 T 13-09-2016 THL1_RS18070 1d4a64758c779160d8721e601036a099 69 SUPERFAMILY SSF50182 18 68 1.2E-15 T 13-09-2016 IPR010920 LSM domain THL1_RS18070 1d4a64758c779160d8721e601036a099 69 Pfam PF06004 Bacterial protein of unknown function (DUF903) 21 68 1.4E-21 T 13-09-2016 IPR010305 Protein of unknown function DUF903 THL1_RS00935 6f2e726f7a579456062bc61a4486a757 71 Gene3D G3DSA:2.40.50.100 6 69 1.2E-20 T 13-09-2016 THL1_RS00935 6f2e726f7a579456062bc61a4486a757 71 SUPERFAMILY SSF50331 6 69 1.51E-15 T 13-09-2016 IPR008995 Molybdate/tungstate binding, C-terminal THL1_RS00935 6f2e726f7a579456062bc61a4486a757 71 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 7 69 1.9E-17 T 13-09-2016 IPR004606 Molybdenum-pterin binding GO:0006810|GO:0030151 THL1_RS00935 6f2e726f7a579456062bc61a4486a757 71 Pfam PF03459 TOBE domain 8 67 3.4E-15 T 13-09-2016 IPR005116 Transport-associated OB, type 1 THL1_RS04275 fdc27f05e9fa264ef8c001189f7cc957 52 Pfam PF03889 Domain of unknown function 10 42 2.4E-15 T 13-09-2016 IPR005589 Protein of unknown function DUF331 THL1_RS03300 3319facc410cdc3da77b21db5843cbce 97 Pfam PF13586 Transposase DDE domain 12 95 2.4E-7 T 13-09-2016 IPR025668 Transposase DDE domain THL1_RS03300 3319facc410cdc3da77b21db5843cbce 97 PANTHER PTHR30007 1 97 8.9E-22 T 13-09-2016 THL1_RS03300 3319facc410cdc3da77b21db5843cbce 97 PANTHER PTHR30007:SF21 1 97 8.9E-22 T 13-09-2016 THL1_RS13365 1c05a61b90ee853ea09be3acdec10722 524 SUPERFAMILY SSF48452 281 333 9.32E-20 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS13365 1c05a61b90ee853ea09be3acdec10722 524 SUPERFAMILY SSF48452 371 493 9.32E-20 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS13365 1c05a61b90ee853ea09be3acdec10722 524 Gene3D G3DSA:1.25.40.10 281 331 7.0E-20 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS13365 1c05a61b90ee853ea09be3acdec10722 524 Gene3D G3DSA:1.25.40.10 369 492 7.0E-20 T 13-09-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 THL1_RS13365 1c05a61b90ee853ea09be3acdec10722 524 Gene3D G3DSA:1.10.10.10 5 98 5.0E-22 T 13-09-2016 IPR011991 Winged helix-turn-helix DNA-binding domain THL1_RS13365 1c05a61b90ee853ea09be3acdec10722 524 Pfam PF00486 Transcriptional regulatory protein, C terminal 21 96 1.3E-16 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS13365 1c05a61b90ee853ea09be3acdec10722 524 SMART SM00028 389 422 24.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS13365 1c05a61b90ee853ea09be3acdec10722 524 SMART SM00028 281 317 16.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS13365 1c05a61b90ee853ea09be3acdec10722 524 SMART SM00028 426 459 140.0 T 13-09-2016 IPR019734 Tetratricopeptide repeat GO:0005515 THL1_RS13365 1c05a61b90ee853ea09be3acdec10722 524 SMART SM00862 21 96 6.6E-15 T 13-09-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THL1_RS13365 1c05a61b90ee853ea09be3acdec10722 524 SUPERFAMILY SSF46894 3 97 1.62E-20 T 13-09-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THL1_RS13365 1c05a61b90ee853ea09be3acdec10722 524 PANTHER PTHR23083 368 492 2.6E-18 T 13-09-2016 THL1_RS13365 1c05a61b90ee853ea09be3acdec10722 524 PANTHER PTHR23083 300 330 2.6E-18 T 13-09-2016 THL1_RS19865 54bb0b55dc20dd54b433b60de6fd8cb1 206 TIGRFAM TIGR04282 glyco_like_cofC: transferase 1, rSAM/selenodomain-associated 9 193 2.5E-42 T 13-09-2016 IPR018641 Transferase 1, rSAM/selenodomain-associated THL1_RS19865 54bb0b55dc20dd54b433b60de6fd8cb1 206 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 54 160 2.5E-28 T 13-09-2016 IPR018641 Transferase 1, rSAM/selenodomain-associated THL1_RS19865 54bb0b55dc20dd54b433b60de6fd8cb1 206 SUPERFAMILY SSF53448 14 200 2.76E-23 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS19865 54bb0b55dc20dd54b433b60de6fd8cb1 206 PANTHER PTHR36529 1 196 1.6E-36 T 13-09-2016 THL1_RS19865 54bb0b55dc20dd54b433b60de6fd8cb1 206 Gene3D G3DSA:3.90.550.10 16 182 2.4E-13 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS24865 a30262070692c587550dc39f8ee0469c 736 PANTHER PTHR15498:SF49 40 277 9.1E-31 T 13-09-2016 THL1_RS24865 a30262070692c587550dc39f8ee0469c 736 PANTHER PTHR15498 40 277 9.1E-31 T 13-09-2016 THL1_RS09475 7411a28482e6181cc4a01ca4b37f0843 433 SUPERFAMILY SSF46626 331 431 2.57E-5 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS09475 7411a28482e6181cc4a01ca4b37f0843 433 Pfam PF06181 Protein of unknown function (DUF989) 4 294 1.7E-128 T 13-09-2016 IPR010389 Domain of unknown function DUF989 THL1_RS28155 e344d5a31b54e5ca20b3052e48958ffc 150 PANTHER PTHR10545:SF39 5 147 3.8E-64 T 13-09-2016 IPR032962 Acetyltransferase HPA2/HPA3 GO:0016746 THL1_RS28155 e344d5a31b54e5ca20b3052e48958ffc 150 Pfam PF00583 Acetyltransferase (GNAT) family 58 137 7.7E-15 T 13-09-2016 IPR000182 GNAT domain GO:0008080 THL1_RS28155 e344d5a31b54e5ca20b3052e48958ffc 150 Gene3D G3DSA:3.40.630.30 2 147 1.3E-35 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS28155 e344d5a31b54e5ca20b3052e48958ffc 150 SUPERFAMILY SSF55729 6 137 1.32E-32 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS28155 e344d5a31b54e5ca20b3052e48958ffc 150 PANTHER PTHR10545 5 147 3.8E-64 T 13-09-2016 THL1_RS15545 562c558fa8caf9535bf49898d9607046 1214 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 897 1214 1.2E-49 T 13-09-2016 IPR007452 Translocation and assembly module TamB THL1_RS15545 562c558fa8caf9535bf49898d9607046 1214 PANTHER PTHR36985 3 1214 7.3E-250 T 13-09-2016 THL1_RS09450 5b8557935df83df78d9713399291368f 272 SUPERFAMILY SSF53850 24 242 6.42E-25 T 13-09-2016 THL1_RS09450 5b8557935df83df78d9713399291368f 272 SMART SM00062 23 246 0.0039 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS09450 5b8557935df83df78d9713399291368f 272 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 25 242 3.9E-11 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS09450 5b8557935df83df78d9713399291368f 272 Gene3D G3DSA:3.40.190.10 22 85 8.4E-9 T 13-09-2016 THL1_RS10825 fda20f9f014eca896465e703620811c8 113 PANTHER PTHR38482 1 113 7.0E-57 T 13-09-2016 THL1_RS10825 fda20f9f014eca896465e703620811c8 113 PIRSF PIRSF021239 1 113 3.4E-53 T 13-09-2016 IPR007437 Putative member of DMT superfamily THL1_RS10825 fda20f9f014eca896465e703620811c8 113 Pfam PF04342 Putative member of DMT superfamily (DUF486) 7 111 2.4E-45 T 13-09-2016 IPR007437 Putative member of DMT superfamily THL1_RS24720 93174a9aab0c51fb6a4354ab74648291 747 PANTHER PTHR15498 41 284 2.4E-26 T 13-09-2016 THL1_RS24720 93174a9aab0c51fb6a4354ab74648291 747 PANTHER PTHR15498:SF49 41 284 2.4E-26 T 13-09-2016 THL1_RS08410 8d0f873f69396255d12dad1143dcd291 479 SUPERFAMILY SSF48695 66 268 7.66E-24 T 13-09-2016 IPR011031 Multihaem cytochrome THL1_RS08410 8d0f873f69396255d12dad1143dcd291 479 Pfam PF13435 Cytochrome c554 and c-prime 70 156 2.9E-9 T 13-09-2016 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674|UniPathway: UPA00653 THL1_RS08410 8d0f873f69396255d12dad1143dcd291 479 Gene3D G3DSA:1.10.710.10 65 249 3.0E-20 T 13-09-2016 IPR023155 Cytochrome c-552/4 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674|UniPathway: UPA00653 THL1_RS26575 7c67fda6bcc631068e2ede12f9bbed1b 84 Pfam PF04355 SmpA / OmlA family 19 46 8.5E-6 T 13-09-2016 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 THL1_RS23335 d954ef7a640515772709735345a69dfe 200 PANTHER PTHR30086:SF0 1 197 4.1E-89 T 13-09-2016 THL1_RS23335 d954ef7a640515772709735345a69dfe 200 PANTHER PTHR30086 1 197 4.1E-89 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS23335 d954ef7a640515772709735345a69dfe 200 Pfam PF01810 LysE type translocator 15 197 1.5E-46 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS02290 b3b391c191ba1aefd9dc758d12a67378 320 PIRSF PIRSF036979 22 315 2.3E-95 T 13-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 THL1_RS02290 b3b391c191ba1aefd9dc758d12a67378 320 ProSitePatterns PS01053 Arginase family signature. 239 260 - T 13-09-2016 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 Reactome: REACT_13 THL1_RS02290 b3b391c191ba1aefd9dc758d12a67378 320 TIGRFAM TIGR01230 agmatinase: agmatinase 43 308 5.2E-73 T 13-09-2016 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|UniPathway: UPA00534 THL1_RS02290 b3b391c191ba1aefd9dc758d12a67378 320 Pfam PF00491 Arginase family 44 308 2.7E-89 T 13-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 THL1_RS02290 b3b391c191ba1aefd9dc758d12a67378 320 SUPERFAMILY SSF52768 23 313 1.46E-94 T 13-09-2016 THL1_RS02290 b3b391c191ba1aefd9dc758d12a67378 320 PANTHER PTHR11358 4 313 5.9E-94 T 13-09-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 THL1_RS02290 b3b391c191ba1aefd9dc758d12a67378 320 Gene3D G3DSA:3.40.800.10 21 315 6.9E-107 T 13-09-2016 IPR023696 Ureohydrolase domain THL1_RS07025 4c94d58e2ccf72766892e7326134df27 315 Pfam PF03547 Membrane transport protein 163 308 3.1E-14 T 13-09-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 THL1_RS07025 4c94d58e2ccf72766892e7326134df27 315 Pfam PF03547 Membrane transport protein 4 162 1.3E-10 T 13-09-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 THL1_RS02450 d9b5570c48d21f2f2432544ff598e05a 141 Gene3D G3DSA:3.30.1330.40 10 139 9.5E-37 T 13-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THL1_RS02450 d9b5570c48d21f2f2432544ff598e05a 141 Pfam PF01042 Endoribonuclease L-PSP 14 136 1.4E-25 T 13-09-2016 IPR006175 YjgF/YER057c/UK114 family THL1_RS02450 d9b5570c48d21f2f2432544ff598e05a 141 SUPERFAMILY SSF55298 12 138 2.36E-32 T 13-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THL1_RS02450 d9b5570c48d21f2f2432544ff598e05a 141 PANTHER PTHR11803 19 137 3.9E-49 T 13-09-2016 IPR006175 YjgF/YER057c/UK114 family THL1_RS02450 d9b5570c48d21f2f2432544ff598e05a 141 PANTHER PTHR11803:SF1 19 137 3.9E-49 T 13-09-2016 THL1_RS26465 39d274fdc63fbcdb9053e03c6393152c 140 Pfam PF03682 Uncharacterised protein family (UPF0158) 1 137 4.7E-38 T 13-09-2016 IPR005361 Uncharacterised protein family UPF0158 THL1_RS26465 39d274fdc63fbcdb9053e03c6393152c 140 SUPERFAMILY SSF51206 50 125 4.97E-5 T 13-09-2016 IPR018490 Cyclic nucleotide-binding-like THL1_RS05160 ffe7c912d27b495a3380a705981f9d8d 207 PANTHER PTHR30328 1 184 5.6E-30 T 13-09-2016 THL1_RS05160 ffe7c912d27b495a3380a705981f9d8d 207 Gene3D G3DSA:1.10.357.10 11 203 5.4E-41 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS05160 ffe7c912d27b495a3380a705981f9d8d 207 SUPERFAMILY SSF48498 86 203 2.18E-18 T 13-09-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THL1_RS05160 ffe7c912d27b495a3380a705981f9d8d 207 Pfam PF13977 Bacterial transcriptional repressor 89 201 1.3E-22 T 13-09-2016 THL1_RS05160 ffe7c912d27b495a3380a705981f9d8d 207 PANTHER PTHR30328:SF11 1 184 5.6E-30 T 13-09-2016 THL1_RS05160 ffe7c912d27b495a3380a705981f9d8d 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 7.4E-10 T 13-09-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THL1_RS05160 ffe7c912d27b495a3380a705981f9d8d 207 SUPERFAMILY SSF46689 11 82 9.23E-15 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS04785 57d70dada560255b6789271fb15d2b4a 107 SUPERFAMILY SSF57716 75 105 2.14E-7 T 13-09-2016 THL1_RS04785 57d70dada560255b6789271fb15d2b4a 107 PANTHER PTHR33823 30 107 4.9E-19 T 13-09-2016 THL1_RS04785 57d70dada560255b6789271fb15d2b4a 107 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 73 104 8.5E-12 T 13-09-2016 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 THL1_RS04785 57d70dada560255b6789271fb15d2b4a 107 PANTHER PTHR33823:SF4 30 107 4.9E-19 T 13-09-2016 THL1_RS10735 f209c50b6549738f6337ffd85b8ab2f4 240 PANTHER PTHR23344 3 240 4.7E-64 T 13-09-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 THL1_RS10735 f209c50b6549738f6337ffd85b8ab2f4 240 Gene3D G3DSA:3.20.20.190 2 236 3.7E-59 T 13-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 THL1_RS10735 f209c50b6549738f6337ffd85b8ab2f4 240 PANTHER PTHR23344:SF20 3 240 4.7E-64 T 13-09-2016 THL1_RS10735 f209c50b6549738f6337ffd85b8ab2f4 240 SUPERFAMILY SSF51695 2 235 3.14E-60 T 13-09-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 THL1_RS10735 f209c50b6549738f6337ffd85b8ab2f4 240 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 231 3.5E-33 T 13-09-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 THL1_RS22275 3a1b7e31c7e915a790bd977596e1d44b 91 SUPERFAMILY SSF101744 2 87 4.45E-23 T 13-09-2016 IPR023534 Rof/RNase P-like THL1_RS22275 3a1b7e31c7e915a790bd977596e1d44b 91 Pfam PF07073 Modulator of Rho-dependent transcription termination (ROF) 7 85 1.5E-29 T 13-09-2016 IPR009778 Modulator of Rho-dependent transcription termination THL1_RS01665 fa9da59105fdb3c6a3df75fb700fcc63 223 SUPERFAMILY SSF49899 2 220 3.01E-69 T 13-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain THL1_RS01665 fa9da59105fdb3c6a3df75fb700fcc63 223 Gene3D G3DSA:2.60.120.200 1 221 2.6E-57 T 13-09-2016 IPR013320 Concanavalin A-like lectin/glucanase domain THL1_RS01665 fa9da59105fdb3c6a3df75fb700fcc63 223 Pfam PF08787 Alginate lyase 2 220 1.8E-53 T 13-09-2016 IPR014895 Alginate lyase 2 THL1_RS17305 f434544cec690b812aaa50575c374ff0 809 Pfam PF03135 CagE, TrbE, VirB family, component of type IV transporter system 181 388 3.2E-12 T 13-09-2016 IPR018145 CagE, TrbE, VirB component of type IV transporter system, central domain GO:0005524 THL1_RS17305 f434544cec690b812aaa50575c374ff0 809 SMART SM00382 440 704 4.2E-7 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS17305 f434544cec690b812aaa50575c374ff0 809 Gene3D G3DSA:3.40.50.300 428 515 4.8E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17305 f434544cec690b812aaa50575c374ff0 809 Gene3D G3DSA:3.40.50.300 603 713 4.8E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS17305 f434544cec690b812aaa50575c374ff0 809 SUPERFAMILY SSF52540 400 742 3.65E-53 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15825 b6a48c1795e34a3892c5508b55636c17 346 Pfam PF13816 Haem-containing dehydratase 44 342 1.1E-96 T 13-09-2016 IPR025702 Haem-containing dehydratase KEGG: 00460+4.99.1.7|KEGG: 00643+4.99.1.7 THL1_RS15825 b6a48c1795e34a3892c5508b55636c17 346 ProDom PD320837 DEHYDRATASE PHENYLACETALDOXIME ALDOXIME LYASE METAL-BINDING IRON HEME TRUNCATION DIRECT 4.2.1.- 1 346 3.0E-114 T 13-09-2016 IPR025702 Haem-containing dehydratase KEGG: 00460+4.99.1.7|KEGG: 00643+4.99.1.7 THL1_RS19675 de069993c000cc1311055f2adfa43ccb 384 SMART SM00047 209 372 1.8E-38 T 13-09-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 THL1_RS19675 de069993c000cc1311055f2adfa43ccb 384 TIGRFAM TIGR02541 flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ 21 367 1.8E-85 T 13-09-2016 IPR013377 Peptidoglycan hydrolase FlgJ GO:0016798|GO:0044780 KEGG: 00130+3.2.1.-|KEGG: 00531+3.2.1.- THL1_RS19675 de069993c000cc1311055f2adfa43ccb 384 PRINTS PR01002 Flagellar protein FlgJ signature 285 304 1.5E-5 T 13-09-2016 THL1_RS19675 de069993c000cc1311055f2adfa43ccb 384 PRINTS PR01002 Flagellar protein FlgJ signature 36 59 1.5E-5 T 13-09-2016 THL1_RS19675 de069993c000cc1311055f2adfa43ccb 384 PRINTS PR01002 Flagellar protein FlgJ signature 14 34 1.5E-5 T 13-09-2016 THL1_RS19675 de069993c000cc1311055f2adfa43ccb 384 PANTHER PTHR33308 219 378 1.7E-40 T 13-09-2016 THL1_RS19675 de069993c000cc1311055f2adfa43ccb 384 Pfam PF10135 Rod binding protein 58 108 4.6E-16 T 13-09-2016 IPR019301 Flagellar protein FlgJ, N-terminal THL1_RS19675 de069993c000cc1311055f2adfa43ccb 384 Gene3D G3DSA:1.10.530.10 211 269 6.9E-5 T 13-09-2016 THL1_RS19675 de069993c000cc1311055f2adfa43ccb 384 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 231 368 1.1E-22 T 13-09-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 THL1_RS19675 de069993c000cc1311055f2adfa43ccb 384 PANTHER PTHR33308:SF3 219 378 1.7E-40 T 13-09-2016 THL1_RS04425 0702ea9f73a3b6d26e34566c949167e6 302 PANTHER PTHR21240 45 290 1.8E-20 T 13-09-2016 THL1_RS04425 0702ea9f73a3b6d26e34566c949167e6 302 Gene3D G3DSA:3.20.20.140 1 285 3.6E-59 T 13-09-2016 THL1_RS04425 0702ea9f73a3b6d26e34566c949167e6 302 PANTHER PTHR21240:SF12 45 290 1.8E-20 T 13-09-2016 THL1_RS04425 0702ea9f73a3b6d26e34566c949167e6 302 SUPERFAMILY SSF51556 1 284 7.94E-51 T 13-09-2016 IPR032466 Metal-dependent hydrolase THL1_RS04425 0702ea9f73a3b6d26e34566c949167e6 302 Pfam PF04909 Amidohydrolase 3 280 2.4E-41 T 13-09-2016 IPR006680 Amidohydrolase-related GO:0016787 THL1_RS25720 c3d4e1e7dbcbcfdfbd809ee4daa68a04 207 PANTHER PTHR30086 1 196 4.1E-60 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS25720 c3d4e1e7dbcbcfdfbd809ee4daa68a04 207 Pfam PF01810 LysE type translocator 15 195 4.4E-38 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS25720 c3d4e1e7dbcbcfdfbd809ee4daa68a04 207 PANTHER PTHR30086:SF10 1 196 4.1E-60 T 13-09-2016 THL1_RS24165 524e338963dba0e046ef687f765a9b32 202 Hamap MF_01207 Sulfoxide reductase heme-binding subunit YedZ [yedZ]. 1 197 22.084 T 13-09-2016 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 THL1_RS24165 524e338963dba0e046ef687f765a9b32 202 Pfam PF01794 Ferric reductase like transmembrane component 43 155 3.9E-13 T 13-09-2016 IPR013130 Ferric reductase transmembrane component-like domain THL1_RS24165 524e338963dba0e046ef687f765a9b32 202 PANTHER PTHR36964 5 202 1.2E-56 T 13-09-2016 THL1_RS13550 f4276b7aa3151b8ecc3563eb13ebcf77 228 Pfam PF08808 RES domain 78 212 5.6E-23 T 13-09-2016 IPR014914 RES domain THL1_RS13550 f4276b7aa3151b8ecc3563eb13ebcf77 228 SMART SM00953 80 204 2.2E-27 T 13-09-2016 IPR014914 RES domain THL1_RS23060 dec600c9956d904292fc0d4d5fd55a4c 226 PANTHER PTHR30258 1 102 7.7E-17 T 13-09-2016 THL1_RS23060 dec600c9956d904292fc0d4d5fd55a4c 226 SUPERFAMILY SSF160246 5 66 1.49E-12 T 13-09-2016 THL1_RS22940 4e4725270de4d58357f4f77865ee90c8 234 SUPERFAMILY SSF158682 81 230 9.42E-25 T 13-09-2016 IPR029024 TerB-like THL1_RS22940 4e4725270de4d58357f4f77865ee90c8 234 Pfam PF04391 Protein of unknown function (DUF533) 46 227 8.1E-66 T 13-09-2016 IPR007486 Inner membrane protein YebE THL1_RS22940 4e4725270de4d58357f4f77865ee90c8 234 Gene3D G3DSA:1.10.3680.10 80 230 3.1E-23 T 13-09-2016 IPR029024 TerB-like THL1_RS16335 399a2ad0755c5a054c0b77da1dc9c4cb 373 PANTHER PTHR30349 68 346 7.5E-20 T 13-09-2016 THL1_RS16335 399a2ad0755c5a054c0b77da1dc9c4cb 373 PANTHER PTHR30349:SF20 68 346 7.5E-20 T 13-09-2016 THL1_RS16335 399a2ad0755c5a054c0b77da1dc9c4cb 373 SUPERFAMILY SSF56349 68 346 1.24E-37 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS16335 399a2ad0755c5a054c0b77da1dc9c4cb 373 Pfam PF00589 Phage integrase family 189 345 7.0E-14 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS16335 399a2ad0755c5a054c0b77da1dc9c4cb 373 Gene3D G3DSA:1.10.443.10 183 347 3.1E-25 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS18910 e1f1370fd5bbaacd4d0eb198395d5f2c 211 Pfam PF11153 Protein of unknown function (DUF2931) 4 209 2.3E-41 T 13-09-2016 IPR021326 Protein of unknown function DUF2931 THL1_RS24750 8ee0695459afcfcb50693e6a32e2b1dd 130 Pfam PF10627 Curli assembly protein CsgE 26 129 4.6E-38 T 13-09-2016 IPR018900 Curli assembly protein CsgE THL1_RS03085 0be54827058460dabcfa5f3ad3c36e4c 118 Pfam PF05717 IS66 Orf2 like protein 10 104 7.4E-31 T 13-09-2016 IPR008878 Transposase IS66, Orf2 THL1_RS03085 0be54827058460dabcfa5f3ad3c36e4c 118 PANTHER PTHR36455 2 118 4.0E-19 T 13-09-2016 THL1_RS06195 c40e5c86340caea16b34def131192854 162 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 61 98 - T 13-09-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 THL1_RS06195 c40e5c86340caea16b34def131192854 162 PANTHER PTHR11079 8 160 6.1E-47 T 13-09-2016 THL1_RS06195 c40e5c86340caea16b34def131192854 162 SUPERFAMILY SSF53927 10 158 1.56E-56 T 13-09-2016 IPR016193 Cytidine deaminase-like GO:0003824 THL1_RS06195 c40e5c86340caea16b34def131192854 162 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 16 157 44.214 T 13-09-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 THL1_RS06195 c40e5c86340caea16b34def131192854 162 Pfam PF14437 MafB19-like deaminase 11 157 7.0E-30 T 13-09-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 THL1_RS06195 c40e5c86340caea16b34def131192854 162 Gene3D G3DSA:3.40.140.10 7 155 2.2E-58 T 13-09-2016 THL1_RS03055 3e0c374604e0441dae140c9ca4f14741 379 Pfam PF13524 Glycosyl transferases group 1 274 356 4.5E-7 T 13-09-2016 THL1_RS03055 3e0c374604e0441dae140c9ca4f14741 379 SUPERFAMILY SSF53756 15 363 1.32E-29 T 13-09-2016 THL1_RS03055 3e0c374604e0441dae140c9ca4f14741 379 Pfam PF09314 Domain of unknown function (DUF1972) 4 177 3.4E-19 T 13-09-2016 IPR015393 Domain of unknown function DUF1972 THL1_RS25365 546b99a4ff2628413e76b3ed07fcdbbd 148 PANTHER PTHR34821 1 147 2.0E-43 T 13-09-2016 THL1_RS25365 546b99a4ff2628413e76b3ed07fcdbbd 148 Pfam PF04657 Putative inner membrane exporter, YdcZ 7 144 1.9E-41 T 13-09-2016 IPR006750 Putative inner membrane exporter, YdcZ THL1_RS25365 546b99a4ff2628413e76b3ed07fcdbbd 148 PANTHER PTHR34821:SF2 1 147 2.0E-43 T 13-09-2016 THL1_RS17350 5e22a9207254f20521d665a7f1ba84d9 86 SMART SM00530 10 66 9.1E-8 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS17350 5e22a9207254f20521d665a7f1ba84d9 86 Pfam PF13560 Helix-turn-helix domain 8 65 2.2E-12 T 13-09-2016 THL1_RS17350 5e22a9207254f20521d665a7f1ba84d9 86 Gene3D G3DSA:1.10.260.40 6 66 2.1E-15 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS17350 5e22a9207254f20521d665a7f1ba84d9 86 SUPERFAMILY SSF47413 5 74 1.75E-14 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS01270 b426ba944e75c29766775568706efa0d 139 Pfam PF14467 Domain of unknown function (DUF4426) 22 138 3.8E-46 T 13-09-2016 IPR025218 Domain of unknown function DUF4426 THL1_RS21150 5489950974df2e3e46b149df8ae2e29a 61 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 57 1.3E-30 T 13-09-2016 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 THL1_RS21150 5489950974df2e3e46b149df8ae2e29a 61 SUPERFAMILY SSF117130 1 54 5.49E-21 T 13-09-2016 THL1_RS21150 5489950974df2e3e46b149df8ae2e29a 61 PANTHER PTHR34984 1 61 5.4E-33 T 13-09-2016 THL1_RS21150 5489950974df2e3e46b149df8ae2e29a 61 Hamap MF_00167 Carbon storage regulator [csrA]. 1 61 20.954 T 13-09-2016 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 THL1_RS21150 5489950974df2e3e46b149df8ae2e29a 61 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 2.0E-11 T 13-09-2016 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 THL1_RS21150 5489950974df2e3e46b149df8ae2e29a 61 PANTHER PTHR34984:SF1 1 61 5.4E-33 T 13-09-2016 THL1_RS21150 5489950974df2e3e46b149df8ae2e29a 61 Pfam PF02599 Global regulator protein family 1 53 9.4E-27 T 13-09-2016 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 THL1_RS03245 c4ff4cba0298525cf02b7b8f23716624 341 PANTHER PTHR30509 3 251 4.9E-54 T 13-09-2016 THL1_RS03245 c4ff4cba0298525cf02b7b8f23716624 341 PANTHER PTHR30509 315 340 4.9E-54 T 13-09-2016 THL1_RS03245 c4ff4cba0298525cf02b7b8f23716624 341 Pfam PF04632 Fusaric acid resistance protein family 11 336 5.3E-103 T 13-09-2016 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0006810 THL1_RS03245 c4ff4cba0298525cf02b7b8f23716624 341 PANTHER PTHR30509:SF1 315 340 4.9E-54 T 13-09-2016 THL1_RS03245 c4ff4cba0298525cf02b7b8f23716624 341 PANTHER PTHR30509:SF1 3 251 4.9E-54 T 13-09-2016 THL1_RS04285 08f1a97882f261e610d1a40a9049256b 202 Gene3D G3DSA:3.30.160.150 18 163 4.1E-31 T 13-09-2016 THL1_RS04285 08f1a97882f261e610d1a40a9049256b 202 Pfam PF04390 Lipopolysaccharide-assembly 9 154 6.3E-17 T 13-09-2016 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 THL1_RS04285 08f1a97882f261e610d1a40a9049256b 202 PANTHER PTHR38098:SF1 1 199 1.6E-45 T 13-09-2016 THL1_RS04285 08f1a97882f261e610d1a40a9049256b 202 PANTHER PTHR38098 1 199 1.6E-45 T 13-09-2016 THL1_RS04285 08f1a97882f261e610d1a40a9049256b 202 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 3 159 21.514 T 13-09-2016 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 THL1_RS23370 418ce893aea9d682cef5f1cf623b5d00 354 Pfam PF09375 Imelysin 37 333 3.2E-55 T 13-09-2016 THL1_RS06520 5fac4e3b21f443261a22136091163f72 460 Pfam PF07044 Protein of unknown function (DUF1329) 90 455 8.9E-129 T 13-09-2016 IPR010752 Protein of unknown function DUF1329 THL1_RS06520 5fac4e3b21f443261a22136091163f72 460 Gene3D G3DSA:2.50.20.10 166 313 1.5E-38 T 13-09-2016 THL1_RS06520 5fac4e3b21f443261a22136091163f72 460 Gene3D G3DSA:2.50.20.10 347 455 1.5E-38 T 13-09-2016 THL1_RS01800 f97598cf38fcde9ec8086b7521ab34a6 176 SMART SM00989 107 175 1.8E-5 T 13-09-2016 IPR004096 4-vinyl reductase, 4VR THL1_RS01800 f97598cf38fcde9ec8086b7521ab34a6 176 SUPERFAMILY SSF111126 8 145 8.37E-17 T 13-09-2016 IPR024096 NO signalling/Golgi transport ligand-binding domain THL1_RS01800 f97598cf38fcde9ec8086b7521ab34a6 176 Gene3D G3DSA:3.30.1380.20 4 145 1.7E-22 T 13-09-2016 THL1_RS13325 a3349045adbbf2996b58dc61cee91c98 78 Pfam PF11391 Protein of unknown function (DUF2798) 15 70 8.8E-7 T 13-09-2016 IPR021529 Protein of unknown function DUF2798 THL1_RS22330 ff70a014f8e584589d27d851f0055a28 135 PANTHER PTHR35535 1 131 1.2E-28 T 13-09-2016 THL1_RS22330 ff70a014f8e584589d27d851f0055a28 135 Pfam PF03724 META domain 27 128 1.9E-30 T 13-09-2016 IPR005184 Domain of unknown function DUF306, Meta/HslJ THL1_RS25315 af3e0b17099fb81c4374d16373ae952c 582 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 9 54 8.0E-7 T 13-09-2016 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal THL1_RS25315 af3e0b17099fb81c4374d16373ae952c 582 Pfam PF09977 Putative Tad-like Flp pilus-assembly 68 152 3.0E-9 T 13-09-2016 IPR018705 Domain of unknown function DUF2134, membrane THL1_RS00695 9076a730c71d7560741855bbbd149a30 290 SUPERFAMILY SSF161098 23 275 2.49E-54 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00695 9076a730c71d7560741855bbbd149a30 290 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 24 279 2.4E-121 T 13-09-2016 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 THL1_RS00695 9076a730c71d7560741855bbbd149a30 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 281 3.9E-18 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS00695 9076a730c71d7560741855bbbd149a30 290 PANTHER PTHR30406:SF1 15 287 4.4E-158 T 13-09-2016 THL1_RS00695 9076a730c71d7560741855bbbd149a30 290 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 25 277 4.3E-97 T 13-09-2016 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 THL1_RS00695 9076a730c71d7560741855bbbd149a30 290 PANTHER PTHR30406 15 287 4.4E-158 T 13-09-2016 THL1_RS00695 9076a730c71d7560741855bbbd149a30 290 Gene3D G3DSA:1.10.3720.10 23 282 3.5E-52 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS16385 d197988306d48ecee3a8b397b7922c21 87 Pfam PF14357 Domain of unknown function (DUF4404) 5 87 3.3E-28 T 13-09-2016 IPR025516 Protein of unknown function DUF4404 THL1_RS17240 678436e22a257ecf87e117b7c9bcee78 538 Pfam PF06980 Protein of unknown function (DUF1302) 4 537 1.0E-133 T 13-09-2016 IPR010727 Protein of unknown function DUF1302 THL1_RS27280 0d1c3524a3c51229cd04068e17259dc5 149 SUPERFAMILY SSF88697 1 148 2.73E-58 T 13-09-2016 IPR015947 PUA-like domain THL1_RS27280 0d1c3524a3c51229cd04068e17259dc5 149 Gene3D G3DSA:3.10.590.10 1 147 8.2E-26 T 13-09-2016 IPR002740 EVE domain THL1_RS27280 0d1c3524a3c51229cd04068e17259dc5 149 Pfam PF01878 EVE domain 3 147 4.5E-51 T 13-09-2016 IPR002740 EVE domain THL1_RS27280 0d1c3524a3c51229cd04068e17259dc5 149 PANTHER PTHR14087 3 148 1.3E-76 T 13-09-2016 THL1_RS17145 4a752d9ff737e9203b483e6e89c9f96c 455 Pfam PF07044 Protein of unknown function (DUF1329) 85 450 6.1E-154 T 13-09-2016 IPR010752 Protein of unknown function DUF1329 THL1_RS17145 4a752d9ff737e9203b483e6e89c9f96c 455 Gene3D G3DSA:2.50.20.10 342 429 1.3E-37 T 13-09-2016 THL1_RS17145 4a752d9ff737e9203b483e6e89c9f96c 455 Gene3D G3DSA:2.50.20.10 161 309 1.3E-37 T 13-09-2016 THL1_RS09200 140ac486ee32e9e0e2d780dda0d283fc 281 Gene3D G3DSA:3.40.50.300 9 198 1.2E-34 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS09200 140ac486ee32e9e0e2d780dda0d283fc 281 Pfam PF07728 AAA domain (dynein-related subfamily) 29 171 6.5E-14 T 13-09-2016 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 THL1_RS09200 140ac486ee32e9e0e2d780dda0d283fc 281 SMART SM00382 25 183 3.8E-8 T 13-09-2016 IPR003593 AAA+ ATPase domain THL1_RS09200 140ac486ee32e9e0e2d780dda0d283fc 281 PANTHER PTHR22908 1 235 1.8E-78 T 13-09-2016 THL1_RS09200 140ac486ee32e9e0e2d780dda0d283fc 281 SUPERFAMILY SSF52540 8 250 1.38E-37 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS11440 62b671eb395208fca62bb34696f389fb 109 Pfam PF04341 Protein of unknown function, DUF485 17 104 5.0E-30 T 13-09-2016 IPR007436 Protein of unknown function DUF485 THL1_RS11440 62b671eb395208fca62bb34696f389fb 109 PANTHER PTHR38598 8 109 9.7E-31 T 13-09-2016 THL1_RS09465 8cc65856b89f16d976f981f08bbd119b 270 SUPERFAMILY SSF111364 16 269 1.57E-50 T 13-09-2016 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 THL1_RS09465 8cc65856b89f16d976f981f08bbd119b 270 Gene3D G3DSA:2.40.230.20 10 255 1.9E-23 T 13-09-2016 IPR018013 Nucleoside-specific channel-forming protein, Tsx-like GO:0009279 THL1_RS17085 a87c119994a8cb33cada4aa196531be2 138 Gene3D G3DSA:3.30.1330.40 8 133 4.5E-39 T 13-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THL1_RS17085 a87c119994a8cb33cada4aa196531be2 138 Pfam PF01042 Endoribonuclease L-PSP 24 132 2.6E-26 T 13-09-2016 IPR006175 YjgF/YER057c/UK114 family THL1_RS17085 a87c119994a8cb33cada4aa196531be2 138 PANTHER PTHR11803 25 134 3.0E-31 T 13-09-2016 IPR006175 YjgF/YER057c/UK114 family THL1_RS17085 a87c119994a8cb33cada4aa196531be2 138 SUPERFAMILY SSF55298 13 133 2.36E-34 T 13-09-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like THL1_RS08130 a5d709fc9f5c1a2eb12b218271d4d951 62 Gene3D G3DSA:3.10.450.50 28 61 2.4E-11 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS08130 a5d709fc9f5c1a2eb12b218271d4d951 62 SUPERFAMILY SSF103642 41 61 1.96E-8 T 13-09-2016 THL1_RS08130 a5d709fc9f5c1a2eb12b218271d4d951 62 Pfam PF02810 SEC-C motif 44 61 2.3E-11 T 13-09-2016 IPR004027 SEC-C motif THL1_RS19450 85c11723445b4034a951b1e706ab83ee 109 Pfam PF01312 FlhB HrpN YscU SpaS Family 8 77 9.8E-18 T 13-09-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THL1_RS19450 85c11723445b4034a951b1e706ab83ee 109 PANTHER PTHR30531 1 92 1.3E-34 T 13-09-2016 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 THL1_RS19450 85c11723445b4034a951b1e706ab83ee 109 SUPERFAMILY SSF160544 6 82 1.83E-20 T 13-09-2016 IPR029025 Type III secretion system substrate exporter, C-terminal THL1_RS19450 85c11723445b4034a951b1e706ab83ee 109 Gene3D G3DSA:3.40.1690.10 7 82 9.6E-23 T 13-09-2016 IPR029025 Type III secretion system substrate exporter, C-terminal THL1_RS20210 7ff703398a24989304e646f1aa7a2c3e 175 Pfam PF11286 Protein of unknown function (DUF3087) 2 167 2.1E-61 T 13-09-2016 IPR021438 Protein of unknown function DUF3087 THL1_RS18820 2011b3b2c65d56caa1b1ee7aa513e662 55 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 5 45 1.9E-9 T 13-09-2016 IPR008621 Cbb3-type cytochrome oxidase component THL1_RS06665 250c508ed3bcf170a1439d3641c8a5cc 142 Pfam PF06803 Protein of unknown function (DUF1232) 72 106 5.1E-11 T 13-09-2016 IPR010652 Protein of unknown function DUF1232 UniPathway: UPA00143 THL1_RS17700 6606a57d2200145c6b337e28aa3050c6 87 Gene3D G3DSA:1.10.443.10 1 73 7.3E-15 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS17700 6606a57d2200145c6b337e28aa3050c6 87 Pfam PF00589 Phage integrase family 6 69 3.1E-10 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS17700 6606a57d2200145c6b337e28aa3050c6 87 SUPERFAMILY SSF56349 2 70 2.35E-11 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS01245 d6c762ad86dc4bb33830620c937ff8dc 447 Gene3D G3DSA:2.50.20.10 336 444 8.0E-32 T 13-09-2016 THL1_RS01245 d6c762ad86dc4bb33830620c937ff8dc 447 Gene3D G3DSA:2.50.20.10 155 303 8.0E-32 T 13-09-2016 THL1_RS01245 d6c762ad86dc4bb33830620c937ff8dc 447 Pfam PF07044 Protein of unknown function (DUF1329) 80 443 1.4E-138 T 13-09-2016 IPR010752 Protein of unknown function DUF1329 THL1_RS10210 8fbe2f9587be2814ab8fb5af5f9f003b 310 PANTHER PTHR23088:SF15 39 110 2.6E-20 T 13-09-2016 THL1_RS10210 8fbe2f9587be2814ab8fb5af5f9f003b 310 PANTHER PTHR23088:SF15 143 216 2.6E-20 T 13-09-2016 THL1_RS10210 8fbe2f9587be2814ab8fb5af5f9f003b 310 Gene3D G3DSA:3.60.110.10 146 214 1.1E-6 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS10210 8fbe2f9587be2814ab8fb5af5f9f003b 310 PANTHER PTHR23088 39 110 2.6E-20 T 13-09-2016 THL1_RS10210 8fbe2f9587be2814ab8fb5af5f9f003b 310 PANTHER PTHR23088 143 216 2.6E-20 T 13-09-2016 THL1_RS10210 8fbe2f9587be2814ab8fb5af5f9f003b 310 SUPERFAMILY SSF56317 77 110 2.49E-7 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS10210 8fbe2f9587be2814ab8fb5af5f9f003b 310 SUPERFAMILY SSF56317 147 214 2.49E-7 T 13-09-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 THL1_RS18805 1dcc6a6e08390f0ecc799b83d510ddb8 211 PANTHER PTHR13136 2 211 7.8E-65 T 13-09-2016 IPR026555 KAT8 regulatory NSL complex subunit 3/Testis-expressed sequence 30 protein THL1_RS18805 1dcc6a6e08390f0ecc799b83d510ddb8 211 Gene3D G3DSA:3.40.50.1820 13 203 1.4E-29 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS18805 1dcc6a6e08390f0ecc799b83d510ddb8 211 SUPERFAMILY SSF53474 4 203 1.41E-23 T 13-09-2016 IPR029058 Alpha/Beta hydrolase fold THL1_RS18805 1dcc6a6e08390f0ecc799b83d510ddb8 211 PANTHER PTHR13136:SF4 2 211 7.8E-65 T 13-09-2016 THL1_RS15860 856aa284dbeadfa087ef7110316209a7 224 Gene3D G3DSA:3.40.50.200 5 213 1.5E-14 T 13-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THL1_RS15860 856aa284dbeadfa087ef7110316209a7 224 SUPERFAMILY SSF52743 6 218 2.36E-24 T 13-09-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THL1_RS23905 49af1a23e283dfb415a907552a209c2b 73 TIGRFAM TIGR02450 TIGR02450: tryptophan-rich conserved hypothetical protein 12 72 1.6E-16 T 13-09-2016 IPR012663 Conserved hypothetical protein CHP02450, tryptophan-rich THL1_RS23905 49af1a23e283dfb415a907552a209c2b 73 Pfam PF09493 Tryptophan-rich protein (DUF2389) 14 73 1.6E-18 T 13-09-2016 IPR012663 Conserved hypothetical protein CHP02450, tryptophan-rich THL1_RS09590 4d85a7d38d6048a4440c14224d0e880c 158 Pfam PF07811 TadE-like protein 14 56 1.0E-11 T 13-09-2016 IPR012495 TadE-like THL1_RS19635 b77555ff4654d31fceca5ebe52849934 98 Pfam PF05400 Flagellar protein FliT 16 94 5.1E-8 T 13-09-2016 IPR008622 Flagellar protein FliT THL1_RS09005 68053548ec6c9fc4d8f7c164c77f560a 113 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 8 100 2.0E-11 T 13-09-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THL1_RS09005 68053548ec6c9fc4d8f7c164c77f560a 113 SUPERFAMILY SSF143011 35 96 2.16E-6 T 13-09-2016 THL1_RS25305 8d05dc6880ae7b7324422b70d093e561 154 Pfam PF01478 Type IV leader peptidase family 6 108 1.4E-9 T 13-09-2016 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 THL1_RS14330 a3e56c8e2dd15f10fd1a88a0c98fd386 103 Pfam PF10048 Predicted integral membrane protein (DUF2282) 36 84 4.8E-25 T 13-09-2016 IPR018740 Protein of unknown function DUF2282, integral membrane THL1_RS12565 32cecd65c912efb7ff358d58d242ece2 149 SUPERFAMILY SSF51316 8 140 3.45E-31 T 13-09-2016 IPR011057 Mss4-like THL1_RS12565 32cecd65c912efb7ff358d58d242ece2 149 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 31 120 5.9E-14 T 13-09-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801|UniPathway: UPA00562 THL1_RS12565 32cecd65c912efb7ff358d58d242ece2 149 PANTHER PTHR33337 6 140 8.9E-12 T 13-09-2016 THL1_RS12565 32cecd65c912efb7ff358d58d242ece2 149 Gene3D G3DSA:3.90.1590.10 3 142 3.8E-31 T 13-09-2016 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0008152|GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801|UniPathway: UPA00562 THL1_RS16320 7cfea71a54a76644591880eefb91c3ad 932 SUPERFAMILY SSF56731 173 274 1.54E-5 T 13-09-2016 THL1_RS16320 7cfea71a54a76644591880eefb91c3ad 932 Pfam PF13155 Toprim-like 179 272 1.3E-14 T 13-09-2016 THL1_RS16320 7cfea71a54a76644591880eefb91c3ad 932 Gene3D G3DSA:3.40.1360.10 176 260 7.7E-6 T 13-09-2016 THL1_RS23800 09db73034d5d4aac26fbac5e959c1e8c 272 PANTHER PTHR22726 34 268 2.6E-68 T 13-09-2016 THL1_RS23800 09db73034d5d4aac26fbac5e959c1e8c 272 PANTHER PTHR22726:SF1 34 268 2.6E-68 T 13-09-2016 THL1_RS23800 09db73034d5d4aac26fbac5e959c1e8c 272 Pfam PF01435 Peptidase family M48 74 256 9.7E-39 T 13-09-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 THL1_RS23800 09db73034d5d4aac26fbac5e959c1e8c 272 Gene3D G3DSA:3.30.2010.10 71 158 3.4E-15 T 13-09-2016 THL1_RS14620 e88703e2338fd84357dc0807d4244f37 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 280 4.3E-27 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS14620 e88703e2338fd84357dc0807d4244f37 315 SUPERFAMILY SSF161098 94 277 4.71E-42 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS14620 e88703e2338fd84357dc0807d4244f37 315 Gene3D G3DSA:1.10.3720.10 94 277 4.4E-43 T 13-09-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 THL1_RS14620 e88703e2338fd84357dc0807d4244f37 315 PANTHER PTHR30177 13 298 1.5E-123 T 13-09-2016 THL1_RS14620 e88703e2338fd84357dc0807d4244f37 315 PANTHER PTHR30177:SF2 13 298 1.5E-123 T 13-09-2016 THL1_RS26125 6595b6e2be433d908766f472c662b2c9 294 PANTHER PTHR22916 1 293 1.3E-52 T 13-09-2016 THL1_RS26125 6595b6e2be433d908766f472c662b2c9 294 Pfam PF00535 Glycosyl transferase family 2 11 173 1.6E-24 T 13-09-2016 IPR001173 Glycosyltransferase 2-like THL1_RS26125 6595b6e2be433d908766f472c662b2c9 294 Gene3D G3DSA:3.90.550.10 8 225 1.4E-50 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS26125 6595b6e2be433d908766f472c662b2c9 294 SUPERFAMILY SSF53448 8 226 6.19E-52 T 13-09-2016 IPR029044 Nucleotide-diphospho-sugar transferases THL1_RS26125 6595b6e2be433d908766f472c662b2c9 294 PANTHER PTHR22916:SF17 1 293 1.3E-52 T 13-09-2016 THL1_RS20510 24a9c4b8d6e0a1c061cf746fc73f9917 153 SUPERFAMILY SSF54427 6 137 1.09E-39 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS20510 24a9c4b8d6e0a1c061cf746fc73f9917 153 Gene3D G3DSA:3.10.450.50 10 137 1.7E-31 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS20510 24a9c4b8d6e0a1c061cf746fc73f9917 153 Pfam PF13577 SnoaL-like domain 8 132 5.9E-27 T 13-09-2016 IPR009959 Polyketide cyclase SnoaL-like domain THL1_RS22030 629a8e2c1e87c5c54b206bea7fb471be 372 Pfam PF06804 NlpB/DapX lipoprotein 36 368 2.2E-27 T 13-09-2016 IPR010653 NlpB/DapX lipoprotein THL1_RS20735 2135801237aff86d1748a171a5dd0eec 303 SUPERFAMILY SSF47823 7 98 5.3E-24 T 13-09-2016 IPR010998 Integrase, Lambda-type, N-terminal THL1_RS20735 2135801237aff86d1748a171a5dd0eec 303 Gene3D G3DSA:1.10.443.10 100 298 1.4E-51 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS20735 2135801237aff86d1748a171a5dd0eec 303 PANTHER PTHR30349:SF34 15 294 5.1E-18 T 13-09-2016 THL1_RS20735 2135801237aff86d1748a171a5dd0eec 303 PANTHER PTHR30349 15 294 5.1E-18 T 13-09-2016 THL1_RS20735 2135801237aff86d1748a171a5dd0eec 303 SUPERFAMILY SSF56349 99 298 1.09E-38 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS20735 2135801237aff86d1748a171a5dd0eec 303 Pfam PF00589 Phage integrase family 133 296 3.8E-14 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS20735 2135801237aff86d1748a171a5dd0eec 303 Gene3D G3DSA:1.10.150.130 7 99 2.1E-23 T 13-09-2016 IPR023109 Integrase/recombinase, N-terminal THL1_RS25985 adcae16bbf86f907be23bec6567af416 151 PANTHER PTHR38774:SF1 2 151 7.5E-50 T 13-09-2016 THL1_RS25985 adcae16bbf86f907be23bec6567af416 151 Pfam PF06853 Protein of unknown function (DUF1249) 27 145 8.2E-44 T 13-09-2016 IPR009659 Protein of unknown function DUF1249 THL1_RS25985 adcae16bbf86f907be23bec6567af416 151 PANTHER PTHR38774 2 151 7.5E-50 T 13-09-2016 THL1_RS08405 25ccc4ec7c4cb7d4e386600343ce25ed 75 SUPERFAMILY SSF46626 19 59 8.03E-5 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS27055 020ae94fcc06e717bbe9dd01e37d80e9 163 Pfam PF13488 Glycine zipper 28 66 4.6E-5 T 13-09-2016 THL1_RS09825 193881ded872499e8c4a78080355ec8b 344 SUPERFAMILY SSF53756 28 306 7.53E-15 T 13-09-2016 THL1_RS14515 e670b8a9ce0f97ff0ff7236d7a7fbd26 289 Gene3D G3DSA:2.40.160.10 195 275 7.0E-4 T 13-09-2016 IPR023614 Porin domain THL1_RS14515 e670b8a9ce0f97ff0ff7236d7a7fbd26 289 SUPERFAMILY SSF56935 189 270 1.53E-5 T 13-09-2016 THL1_RS14515 e670b8a9ce0f97ff0ff7236d7a7fbd26 289 Pfam PF13557 Putative MetA-pathway of phenol degradation 58 284 3.1E-32 T 13-09-2016 IPR025737 MetA-pathway of phenol degradation, putative THL1_RS05795 949368c4168eaa7e4fddff2b401ace10 335 Pfam PF04245 37-kD nucleoid-associated bacterial protein 7 327 6.7E-90 T 13-09-2016 IPR007358 Nucleoid-associated protein NdpA GO:0009295 THL1_RS05795 949368c4168eaa7e4fddff2b401ace10 335 Hamap MF_00730 Nucleoid-associated protein YejK [yejK]. 1 333 40.351 T 13-09-2016 IPR007358 Nucleoid-associated protein NdpA GO:0009295 THL1_RS05795 949368c4168eaa7e4fddff2b401ace10 335 PANTHER PTHR38772 1 335 1.8E-163 T 13-09-2016 THL1_RS25040 a73c25eee6014a265f2b1f04b4c226de 176 Gene3D G3DSA:3.30.1360.100 83 153 1.7E-4 T 13-09-2016 IPR023229 Type II secretion system protein M, periplasmic domain THL1_RS25040 a73c25eee6014a265f2b1f04b4c226de 176 Pfam PF04612 Type II secretion system (T2SS), protein M 8 153 2.8E-22 T 13-09-2016 IPR007690 Type II secretion system, protein M GO:0006858 THL1_RS23145 7a1a41164decf23231ff6611fe2e6220 140 Pfam PF13511 Domain of unknown function (DUF4124) 6 55 3.7E-16 T 13-09-2016 IPR025392 Domain of unknown function DUF4124 THL1_RS15995 a358c3d962e181f99413cbf03611925a 185 Pfam PF06475 Putative glycolipid-binding 10 184 3.5E-44 T 13-09-2016 IPR009467 Putative glycolipid-binding protein THL1_RS15995 a358c3d962e181f99413cbf03611925a 185 SUPERFAMILY SSF159275 14 185 1.7E-40 T 13-09-2016 THL1_RS14495 deca2ebb7e3a1163e682124dd9599518 516 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 27 504 5.0E-140 T 13-09-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 THL1_RS14495 deca2ebb7e3a1163e682124dd9599518 516 PANTHER PTHR30047 21 514 6.5E-119 T 13-09-2016 THL1_RS11885 5f822cd5cd19f0fc6fc4414f7fd564e9 385 Pfam PF07148 Maltose operon periplasmic protein precursor (MalM) 256 383 1.3E-23 T 13-09-2016 IPR010794 Maltose operon periplasmic GO:0008643|GO:0042597 THL1_RS25650 8ab83e05b43499b88fce649e23286b06 190 Pfam PF04955 HupE / UreJ protein 11 187 3.2E-59 T 13-09-2016 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein THL1_RS25650 8ab83e05b43499b88fce649e23286b06 190 PIRSF PIRSF016919 1 190 3.8E-62 T 13-09-2016 IPR007038 Hydrogenase/Urease accessory protein HupE/UreJ protein THL1_RS23140 1f976e6213e2463fd14333620f327e9b 119 Pfam PF07238 PilZ domain 4 94 1.8E-6 T 13-09-2016 IPR009875 PilZ domain GO:0035438 THL1_RS17150 4cd5ca37be6fce291861dd243bace9b8 623 Pfam PF06980 Protein of unknown function (DUF1302) 31 623 9.0E-219 T 13-09-2016 IPR010727 Protein of unknown function DUF1302 THL1_RS15325 8e1424dad050bdefcf44d4b2c1da9255 205 PANTHER PTHR30086 2 205 5.2E-34 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS15325 8e1424dad050bdefcf44d4b2c1da9255 205 Pfam PF01810 LysE type translocator 18 204 4.6E-29 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS16635 dfcc366573e3feebb0c56923df783894 2010 Gene3D G3DSA:3.40.50.300 764 838 3.1E-4 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16635 dfcc366573e3feebb0c56923df783894 2010 Gene3D G3DSA:3.40.50.300 274 317 8.2E-5 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16635 dfcc366573e3feebb0c56923df783894 2010 Gene3D G3DSA:3.40.50.300 355 461 8.2E-5 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16635 dfcc366573e3feebb0c56923df783894 2010 SUPERFAMILY SSF52540 274 502 1.08E-10 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS18370 9fe624ea27d89096a28688eadf84d5ae 273 SUPERFAMILY SSF53850 28 254 4.78E-23 T 13-09-2016 THL1_RS18370 9fe624ea27d89096a28688eadf84d5ae 273 Gene3D G3DSA:3.40.190.10 27 92 0.001 T 13-09-2016 THL1_RS18370 9fe624ea27d89096a28688eadf84d5ae 273 SMART SM00062 29 258 0.0079 T 13-09-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THL1_RS16740 a59a16bd13a535c7c9a950d6d4deb2f1 176 PANTHER PTHR37512 1 175 2.6E-77 T 13-09-2016 THL1_RS16740 a59a16bd13a535c7c9a950d6d4deb2f1 176 Gene3D G3DSA:3.40.50.300 1 165 3.2E-47 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16740 a59a16bd13a535c7c9a950d6d4deb2f1 176 SUPERFAMILY SSF52540 2 163 3.4E-21 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS16740 a59a16bd13a535c7c9a950d6d4deb2f1 176 Pfam PF13521 AAA domain 5 160 1.4E-27 T 13-09-2016 THL1_RS09380 e0f4678655bc9398ffa620c9f99427ec 338 Pfam PF10974 Protein of unknown function (DUF2804) 8 337 2.9E-76 T 13-09-2016 IPR021243 Protein of unknown function DUF2804 THL1_RS09380 e0f4678655bc9398ffa620c9f99427ec 338 PANTHER PTHR35868 1 338 6.7E-152 T 13-09-2016 THL1_RS09380 e0f4678655bc9398ffa620c9f99427ec 338 PANTHER PTHR35868:SF2 1 338 6.7E-152 T 13-09-2016 THL1_RS21385 36e9b1dd9d9465c6dc8dc1943d84ded6 147 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 5 138 8.0E-19 T 13-09-2016 IPR009936 Protein of unknown function DUF1468 THL1_RS06615 fd67acd1e78b354457d01791f03671e6 243 PANTHER PTHR34979 4 236 3.5E-51 T 13-09-2016 THL1_RS06615 fd67acd1e78b354457d01791f03671e6 243 Pfam PF03591 AzlC protein 16 158 5.3E-45 T 13-09-2016 IPR011606 Branched-chain amino acid transport, permease THL1_RS22280 9c42f03d8c495c4dd46994265a0a2977 179 Pfam PF09831 Uncharacterized protein conserved in bacteria (DUF2058) 4 179 1.1E-60 T 13-09-2016 IPR018636 Protein of unknown function DUF2058 THL1_RS23735 732c523202f89852ddb7b0c05110e542 624 Pfam PF06980 Protein of unknown function (DUF1302) 31 624 3.6E-225 T 13-09-2016 IPR010727 Protein of unknown function DUF1302 THL1_RS21530 2f08aa329d60a90a209a6e6edd9c1b8f 358 Pfam PF09925 Predicted membrane protein (DUF2157) 46 181 1.5E-19 T 13-09-2016 IPR018677 Domain of unknown function DUF2157 THL1_RS22645 fe3fae9b86eb17c9cd0ca72a0ecfc1a1 260 Pfam PF00557 Metallopeptidase family M24 12 241 9.4E-59 T 13-09-2016 IPR000994 Peptidase M24, structural domain THL1_RS22645 fe3fae9b86eb17c9cd0ca72a0ecfc1a1 260 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 167 185 - T 13-09-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 THL1_RS22645 fe3fae9b86eb17c9cd0ca72a0ecfc1a1 260 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 249 1.6E-105 T 13-09-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 THL1_RS22645 fe3fae9b86eb17c9cd0ca72a0ecfc1a1 260 Hamap MF_01974 Methionine aminopeptidase [map]. 3 250 44.254 T 13-09-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 THL1_RS22645 fe3fae9b86eb17c9cd0ca72a0ecfc1a1 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 69 82 9.0E-23 T 13-09-2016 IPR001714 Peptidase M24, methionine aminopeptidase THL1_RS22645 fe3fae9b86eb17c9cd0ca72a0ecfc1a1 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 161 173 9.0E-23 T 13-09-2016 IPR001714 Peptidase M24, methionine aminopeptidase THL1_RS22645 fe3fae9b86eb17c9cd0ca72a0ecfc1a1 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 192 204 9.0E-23 T 13-09-2016 IPR001714 Peptidase M24, methionine aminopeptidase THL1_RS22645 fe3fae9b86eb17c9cd0ca72a0ecfc1a1 260 PRINTS PR00599 Methionine aminopeptidase-1 signature 91 107 9.0E-23 T 13-09-2016 IPR001714 Peptidase M24, methionine aminopeptidase THL1_RS22645 fe3fae9b86eb17c9cd0ca72a0ecfc1a1 260 Gene3D G3DSA:3.90.230.10 4 253 2.7E-105 T 13-09-2016 IPR000994 Peptidase M24, structural domain THL1_RS22645 fe3fae9b86eb17c9cd0ca72a0ecfc1a1 260 PANTHER PTHR10804:SF75 1 257 2.1E-177 T 13-09-2016 THL1_RS22645 fe3fae9b86eb17c9cd0ca72a0ecfc1a1 260 SUPERFAMILY SSF55920 4 253 6.28E-97 T 13-09-2016 IPR000994 Peptidase M24, structural domain THL1_RS22645 fe3fae9b86eb17c9cd0ca72a0ecfc1a1 260 PANTHER PTHR10804 1 257 2.1E-177 T 13-09-2016 THL1_RS10615 e8b41215e347bd29c3df487976b64009 76 Gene3D G3DSA:2.30.30.320 2 68 5.2E-33 T 13-09-2016 IPR023387 DUF1653-like domain THL1_RS10615 e8b41215e347bd29c3df487976b64009 76 Pfam PF07866 Protein of unknown function (DUF1653) 5 64 2.6E-30 T 13-09-2016 IPR023387 DUF1653-like domain THL1_RS15775 12d50d60f2f7a2affd176b9f2d06fda6 416 Gene3D G3DSA:2.40.160.10 34 416 1.1E-142 T 13-09-2016 IPR023614 Porin domain THL1_RS15775 12d50d60f2f7a2affd176b9f2d06fda6 416 Pfam PF03573 outer membrane porin, OprD family 29 414 5.6E-153 T 13-09-2016 IPR005318 Outer membrane porin, bacterial GO:0006810|GO:0015288|GO:0016021 THL1_RS15775 12d50d60f2f7a2affd176b9f2d06fda6 416 PANTHER PTHR34596 1 416 1.5E-160 T 13-09-2016 THL1_RS25945 9f324b731147b96d5a6b6d5a6ca83439 508 Pfam PF10144 Bacterial virulence factor haemolysin 36 158 3.6E-7 T 13-09-2016 IPR019305 Uncharacterised protein family Smp THL1_RS06140 bbebf59d00e60a6aeced713f1efee59a 280 Pfam PF00482 Type II secretion system (T2SS), protein F 133 262 3.3E-12 T 13-09-2016 IPR018076 Type II secretion system F domain THL1_RS06140 bbebf59d00e60a6aeced713f1efee59a 280 PANTHER PTHR35007 1 273 3.7E-20 T 13-09-2016 THL1_RS10725 0b00c569eb6ebaabaa0a9fd118c321aa 75 Pfam PF04400 Protein of unknown function (DUF539) 21 59 2.4E-13 T 13-09-2016 IPR007495 (Na+)-NQR maturation factor NqrM THL1_RS10725 0b00c569eb6ebaabaa0a9fd118c321aa 75 PANTHER PTHR40691 1 75 9.3E-25 T 13-09-2016 THL1_RS22255 1807ce7e94d313d5be44b13a1afae59e 342 Pfam PF09839 Uncharacterized protein conserved in bacteria (DUF2066) 21 245 3.5E-66 T 13-09-2016 IPR018642 Protein of unknown function DUF2066 THL1_RS01060 ea3c8f6af14bfae2596dadc3d6ee3b37 157 Gene3D G3DSA:3.60.21.10 5 147 4.7E-32 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS01060 ea3c8f6af14bfae2596dadc3d6ee3b37 157 SUPERFAMILY SSF56300 2 156 6.43E-36 T 13-09-2016 IPR029052 Metallo-dependent phosphatase-like THL1_RS01060 ea3c8f6af14bfae2596dadc3d6ee3b37 157 PANTHER PTHR11124 1 154 3.4E-34 T 13-09-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 THL1_RS01060 ea3c8f6af14bfae2596dadc3d6ee3b37 157 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 5 147 5.7E-24 T 13-09-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 THL1_RS01060 ea3c8f6af14bfae2596dadc3d6ee3b37 157 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 5 141 6.3E-34 T 13-09-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type THL1_RS25300 27be1ccb97b29410f99cfad04702f35e 150 Pfam PF07811 TadE-like protein 15 57 5.6E-6 T 13-09-2016 IPR012495 TadE-like THL1_RS26800 dc09e5b1495a3df31bfc083b81f36078 72 Pfam PF05930 Prophage CP4-57 regulatory protein (AlpA) 12 61 5.6E-16 T 13-09-2016 IPR010260 Prophage CP4-57 regulatory protein (AlpA) THL1_RS28320 40a12dea3da11f50822872cc43dcf9f9 156 SUPERFAMILY SSF110087 3 148 1.83E-46 T 13-09-2016 IPR007410 DR1885-like metal-binding protein THL1_RS28320 40a12dea3da11f50822872cc43dcf9f9 156 PANTHER PTHR36302 7 145 5.0E-32 T 13-09-2016 THL1_RS28320 40a12dea3da11f50822872cc43dcf9f9 156 Pfam PF04314 Protein of unknown function (DUF461) 30 139 5.3E-37 T 13-09-2016 IPR007410 DR1885-like metal-binding protein THL1_RS28320 40a12dea3da11f50822872cc43dcf9f9 156 PANTHER PTHR36302:SF1 7 145 5.0E-32 T 13-09-2016 THL1_RS10050 e148cf0fafeec52de3d981a2866bc7e7 100 SUPERFAMILY SSF56349 5 92 4.12E-7 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS10050 e148cf0fafeec52de3d981a2866bc7e7 100 Gene3D G3DSA:1.10.443.10 6 92 1.6E-10 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS20605 9118696e7d0ef5d86d8d6092f1378738 76 Gene3D G3DSA:1.10.357.10 5 70 7.6E-4 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS05250 5d94562ed736048f9076be20899ab027 238 Pfam PF04402 Protein of unknown function (DUF541) 35 229 2.0E-25 T 13-09-2016 IPR007497 Protein of unknown function DUF541 THL1_RS22615 c81a746aa16222d678ec31fed09285ad 271 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 224 250 - T 13-09-2016 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00557 THL1_RS22615 c81a746aa16222d678ec31fed09285ad 271 Pfam PF01148 Cytidylyltransferase family 3 264 2.0E-61 T 13-09-2016 THL1_RS22615 c81a746aa16222d678ec31fed09285ad 271 PANTHER PTHR13773 1 259 3.2E-64 T 13-09-2016 THL1_RS10245 81237fd4992ac1e7b1fc23ef4717497f 314 Pfam PF08907 Domain of unknown function (DUF1853) 20 305 1.3E-100 T 13-09-2016 IPR015003 Protein of unknown function DUF1853 THL1_RS28260 7174b31b7a8a0ae363d23ac3f6803194 191 SUPERFAMILY SSF46689 4 66 4.46E-10 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS28260 7174b31b7a8a0ae363d23ac3f6803194 191 Gene3D G3DSA:1.10.357.10 8 180 3.0E-16 T 13-09-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 THL1_RS08285 f641e281c73e9cb37ebe7dd2041e3f05 66 Pfam PF07869 Protein of unknown function (DUF1656) 4 59 8.9E-22 T 13-09-2016 IPR012451 Protein of unknown function DUF1656 THL1_RS06620 c126e3d477b8782cb55556631a73ec29 109 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 3 101 9.8E-22 T 13-09-2016 IPR008407 Branched-chain amino acid transport, AzlD THL1_RS19470 7e9b217dfa50b9a7992935ff05fb017d 285 PIRSF PIRSF020479 1 285 1.1E-99 T 13-09-2016 IPR014506 Uncharacterised conserved protein UCP020479, signal transduction CheW-like THL1_RS19470 7e9b217dfa50b9a7992935ff05fb017d 285 SUPERFAMILY SSF50341 135 272 2.62E-16 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS19470 7e9b217dfa50b9a7992935ff05fb017d 285 Pfam PF01584 CheW-like domain 140 271 1.3E-14 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS19470 7e9b217dfa50b9a7992935ff05fb017d 285 SMART SM00260 136 271 3.3E-19 T 13-09-2016 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 THL1_RS20425 ad32843614d1d4661c453a1859d92262 122 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 22 78 3.6E-23 T 13-09-2016 IPR025161 Putative transposase IS4/IS5 family THL1_RS20425 ad32843614d1d4661c453a1859d92262 122 PANTHER PTHR30007 25 115 2.3E-25 T 13-09-2016 THL1_RS28330 241d3ba9bee2a361d47fc45ba75a87a9 127 Pfam PF11162 Protein of unknown function (DUF2946) 11 123 4.5E-12 T 13-09-2016 IPR021333 Protein of unknown function DUF2946 THL1_RS10235 13481fc0c839ce3c21ec7c371019c7c0 432 PANTHER PTHR15498:SF49 43 277 1.2E-35 T 13-09-2016 THL1_RS10235 13481fc0c839ce3c21ec7c371019c7c0 432 PANTHER PTHR15498 43 277 1.2E-35 T 13-09-2016 THL1_RS17505 7f21c3aac71c23df1a7ff3547c2582fd 325 Pfam PF02653 Branched-chain amino acid transport system / permease component 41 304 1.9E-32 T 13-09-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 THL1_RS17505 7f21c3aac71c23df1a7ff3547c2582fd 325 PANTHER PTHR30482 15 316 9.8E-101 T 13-09-2016 THL1_RS17505 7f21c3aac71c23df1a7ff3547c2582fd 325 PANTHER PTHR30482:SF8 15 316 9.8E-101 T 13-09-2016 THL1_RS05030 86d5a06c2c239358a3b979e013815d58 57 Pfam PF11293 Protein of unknown function (DUF3094) 2 56 3.2E-35 T 13-09-2016 IPR021444 Protein of unknown function DUF3094 THL1_RS15055 47364b5c04a03bdd90c1db4ac8a7c9f4 310 Pfam PF05707 Zonular occludens toxin (Zot) 2 193 1.9E-26 T 13-09-2016 IPR008900 Zona occludens toxin THL1_RS15055 47364b5c04a03bdd90c1db4ac8a7c9f4 310 Gene3D G3DSA:3.40.50.300 1 195 1.2E-22 T 13-09-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase THL1_RS15490 3215594311ee45dbeaeb09ab80af047e 149 SUPERFAMILY SSF46626 32 118 8.08E-9 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS15490 3215594311ee45dbeaeb09ab80af047e 149 Gene3D G3DSA:1.10.760.10 32 123 1.5E-4 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS23620 9f50e3ce90604c42aa533e59190c46fa 113 Pfam PF08888 HopJ type III effector protein 5 109 2.3E-38 T 13-09-2016 IPR014984 HopJ type III effector protein THL1_RS23620 9f50e3ce90604c42aa533e59190c46fa 113 Gene3D G3DSA:3.20.160.10 8 112 9.1E-44 T 13-09-2016 THL1_RS16215 d7cde53d52f7ac1db280bb17a2d68776 143 Pfam PF06995 Phage P2 GpU 6 125 5.9E-45 T 13-09-2016 IPR009734 Myoviridae, GpU THL1_RS16215 d7cde53d52f7ac1db280bb17a2d68776 143 PIRSF PIRSF029208 1 143 1.9E-59 T 13-09-2016 IPR016912 Bacteriophage P2, GpU THL1_RS19600 292a97f3de6a1906403ee4a292413274 265 Pfam PF02108 Flagellar assembly protein FliH 109 230 6.5E-33 T 13-09-2016 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE THL1_RS19600 292a97f3de6a1906403ee4a292413274 265 SUPERFAMILY SSF160527 156 236 2.48E-5 T 13-09-2016 THL1_RS19600 292a97f3de6a1906403ee4a292413274 265 PANTHER PTHR34982:SF2 9 253 6.5E-69 T 13-09-2016 THL1_RS19600 292a97f3de6a1906403ee4a292413274 265 PANTHER PTHR34982 9 253 6.5E-69 T 13-09-2016 THL1_RS12745 b5f3580660fd40fc3f862b6466c84b08 471 PANTHER PTHR11785 14 417 7.3E-22 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS12745 b5f3580660fd40fc3f862b6466c84b08 471 PIRSF PIRSF006060 3 468 1.8E-45 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS12745 b5f3580660fd40fc3f862b6466c84b08 471 Pfam PF13520 Amino acid permease 18 423 6.7E-31 T 13-09-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 THL1_RS00500 b8248059e8e44d67c954181bc29a5270 71 Pfam PF06568 Domain of unknown function (DUF1127) 28 62 6.1E-6 T 13-09-2016 IPR009506 Protein of unknown function DUF1127 THL1_RS16910 9976083e0bc66047d10fbeef1c954364 159 SMART SM00953 14 140 6.4E-19 T 13-09-2016 IPR014914 RES domain THL1_RS16910 9976083e0bc66047d10fbeef1c954364 159 Pfam PF08808 RES domain 4 139 4.1E-20 T 13-09-2016 IPR014914 RES domain THL1_RS16765 ceea67bfcdf8c87a7a0bce22710d93b0 359 SUPERFAMILY SSF52151 48 110 2.88E-14 T 13-09-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THL1_RS16765 ceea67bfcdf8c87a7a0bce22710d93b0 359 SUPERFAMILY SSF52151 160 322 2.88E-14 T 13-09-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 THL1_RS04500 cc73e5e57917d159e9a388420d0fd410 203 SMART SM00479 3 170 1.9E-34 T 13-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III THL1_RS04500 cc73e5e57917d159e9a388420d0fd410 203 Gene3D G3DSA:3.30.420.10 3 169 4.7E-45 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS04500 cc73e5e57917d159e9a388420d0fd410 203 SUPERFAMILY SSF53098 4 171 1.71E-44 T 13-09-2016 IPR012337 Ribonuclease H-like domain GO:0003676 THL1_RS04500 cc73e5e57917d159e9a388420d0fd410 203 Pfam PF00929 Exonuclease 6 160 4.2E-24 T 13-09-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III THL1_RS04500 cc73e5e57917d159e9a388420d0fd410 203 PANTHER PTHR30231 3 160 1.3E-35 T 13-09-2016 THL1_RS04010 4ef7a502b04fd4236f7515ca3cc2bc1d 423 PANTHER PTHR30250 1 417 8.2E-24 T 13-09-2016 THL1_RS04010 4ef7a502b04fd4236f7515ca3cc2bc1d 423 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 326 400 8.5E-13 T 13-09-2016 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain THL1_RS04010 4ef7a502b04fd4236f7515ca3cc2bc1d 423 Pfam PF01943 Polysaccharide biosynthesis protein 26 272 1.9E-15 T 13-09-2016 IPR002797 Polysaccharide biosynthesis protein GO:0016020 THL1_RS20025 829b2146afd63b8620e9e76531ee36f0 225 Pfam PF12261 Thermostable hemolysin 29 199 3.0E-60 T 13-09-2016 IPR022050 Thermostable hemolysin THL1_RS05825 63e0a9bef17cf0b1eb7568476530b4ef 203 PANTHER PTHR10283:SF12 18 202 1.7E-92 T 13-09-2016 THL1_RS05825 63e0a9bef17cf0b1eb7568476530b4ef 203 Pfam PF03600 Citrate transporter 23 201 1.7E-19 T 13-09-2016 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 THL1_RS05825 63e0a9bef17cf0b1eb7568476530b4ef 203 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 151 167 - T 13-09-2016 IPR031312 Sodium/sulphate symporter, conserved site THL1_RS05825 63e0a9bef17cf0b1eb7568476530b4ef 203 PANTHER PTHR10283 18 202 1.7E-92 T 13-09-2016 THL1_RS25440 3eed6a1db4aadb9598ab1a50edbd8204 356 PIRSF PIRSF029693 1 356 1.3E-209 T 13-09-2016 IPR016936 Uncharacterised conserved protein UCP029693 THL1_RS25440 3eed6a1db4aadb9598ab1a50edbd8204 356 Pfam PF10095 Uncharacterized protein conserved in bacteria (DUF2333) 29 356 2.8E-160 T 13-09-2016 IPR016936 Uncharacterised conserved protein UCP029693 THL1_RS16280 3f4573ddd43d08ac3ec0b1a0abd5657b 121 SUPERFAMILY SSF47413 3 69 1.69E-10 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS16280 3f4573ddd43d08ac3ec0b1a0abd5657b 121 SMART SM00530 10 64 6.8E-4 T 13-09-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THL1_RS16280 3f4573ddd43d08ac3ec0b1a0abd5657b 121 Gene3D G3DSA:1.10.260.40 6 68 8.8E-12 T 13-09-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 THL1_RS23210 0a4e044357e872923db1e02917082569 203 Pfam PF11008 Protein of unknown function (DUF2846) 16 145 1.5E-30 T 13-09-2016 IPR022548 Domain of unknown function DUF2846 THL1_RS13735 eaf2d95eb61d04f26a7c293e40349d00 340 PANTHER PTHR33376 6 340 2.1E-44 T 13-09-2016 THL1_RS13735 eaf2d95eb61d04f26a7c293e40349d00 340 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 30 313 1.3E-52 T 13-09-2016 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0006810|GO:0030288 THL1_RS11525 c1d071377f41fdde1c6eb75660157d5e 79 Pfam PF06568 Domain of unknown function (DUF1127) 29 64 1.6E-12 T 13-09-2016 IPR009506 Protein of unknown function DUF1127 THL1_RS00770 33cc86fbdf0bcb39ec0d2c8b244daeb2 138 TIGRFAM TIGR00807 malonate_madL: malonate transporter, MadL subunit 1 121 1.1E-57 T 13-09-2016 IPR004690 Malonate transporter MadL subunit GO:0016020 THL1_RS00770 33cc86fbdf0bcb39ec0d2c8b244daeb2 138 Pfam PF03817 Malonate transporter MadL subunit 1 117 1.8E-47 T 13-09-2016 IPR004690 Malonate transporter MadL subunit GO:0016020 THL1_RS24200 94d85cfc7b32f05580f3252376d82339 152 Pfam PF13511 Domain of unknown function (DUF4124) 10 58 3.1E-18 T 13-09-2016 IPR025392 Domain of unknown function DUF4124 THL1_RS07050 01db217eb13245606ea60b17f5709638 270 SUPERFAMILY SSF100950 7 253 1.67E-45 T 13-09-2016 THL1_RS07050 01db217eb13245606ea60b17f5709638 270 Gene3D G3DSA:3.40.810.20 6 254 2.1E-61 T 13-09-2016 THL1_RS07050 01db217eb13245606ea60b17f5709638 270 SMART SM00882 12 218 0.0011 T 13-09-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 THL1_RS11670 723cd4d0f865e949b635f554bae6314b 311 Pfam PF04773 FecR protein 106 195 1.6E-17 T 13-09-2016 IPR006860 FecR protein THL1_RS11670 723cd4d0f865e949b635f554bae6314b 311 PANTHER PTHR30273:SF3 1 310 2.7E-100 T 13-09-2016 THL1_RS11670 723cd4d0f865e949b635f554bae6314b 311 Pfam PF16220 Domain of unknown function (DUF4880) 2 42 9.5E-14 T 13-09-2016 IPR032623 FecR, N-terminal THL1_RS11670 723cd4d0f865e949b635f554bae6314b 311 PIRSF PIRSF018266 1 309 3.7E-81 T 13-09-2016 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component THL1_RS11670 723cd4d0f865e949b635f554bae6314b 311 PANTHER PTHR30273 1 310 2.7E-100 T 13-09-2016 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component THL1_RS10270 91238a63266740d20fc8ec6f08439d26 276 Pfam PF10977 Protein of unknown function (DUF2797) 38 271 6.1E-97 T 13-09-2016 IPR021246 Protein of unknown function DUF2797 THL1_RS03725 ad8e5676b8c39cf20cbe7121fedea64f 243 PANTHER PTHR36925 1 242 1.9E-76 T 13-09-2016 THL1_RS03725 ad8e5676b8c39cf20cbe7121fedea64f 243 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 3 236 7.4E-56 T 13-09-2016 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 THL1_RS00230 0844ac7d3ffe476bcb511dd5c6fd9aa4 88 Pfam PF09526 Probable metal-binding protein (DUF2387) 4 78 1.0E-35 T 13-09-2016 IPR012658 Conserved hypothetical protein CHP02443 THL1_RS00230 0844ac7d3ffe476bcb511dd5c6fd9aa4 88 TIGRFAM TIGR02443 TIGR02443: conserved hypothetical protein 5 52 2.6E-22 T 13-09-2016 IPR012658 Conserved hypothetical protein CHP02443 THL1_RS27505 7202609eea58a5de7414ae22cff0c884 233 PANTHER PTHR38765 1 233 2.9E-80 T 13-09-2016 THL1_RS27505 7202609eea58a5de7414ae22cff0c884 233 Pfam PF04340 Protein of unknown function, DUF484 10 226 3.7E-78 T 13-09-2016 IPR007435 Protein of unknown function DUF484 THL1_RS20070 193aaeeeae88d7ed1ba44daaee88d8d8 173 Gene3D G3DSA:2.40.70.10 30 159 6.4E-37 T 13-09-2016 IPR021109 Aspartic peptidase domain THL1_RS20070 193aaeeeae88d7ed1ba44daaee88d8d8 173 PANTHER PTHR38037 27 163 9.6E-39 T 13-09-2016 THL1_RS20070 193aaeeeae88d7ed1ba44daaee88d8d8 173 SUPERFAMILY SSF50630 31 165 4.18E-37 T 13-09-2016 IPR021109 Aspartic peptidase domain THL1_RS20070 193aaeeeae88d7ed1ba44daaee88d8d8 173 Pfam PF05618 Putative ATP-dependant zinc protease 31 166 1.1E-38 T 13-09-2016 THL1_RS07310 ef015b215cbb6ccf3c377a2eb25c2010 196 Pfam PF06684 Amino acid synthesis 5 181 3.3E-71 T 13-09-2016 IPR009569 Amino acid synthesis, putative THL1_RS07310 ef015b215cbb6ccf3c377a2eb25c2010 196 SUPERFAMILY SSF160519 1 191 2.22E-70 T 13-09-2016 IPR009569 Amino acid synthesis, putative THL1_RS07310 ef015b215cbb6ccf3c377a2eb25c2010 196 Gene3D G3DSA:3.30.1330.110 1 192 1.5E-84 T 13-09-2016 IPR009569 Amino acid synthesis, putative THL1_RS21085 c0c530f63cc9751c9f4e6887b04ee87e 214 Gene3D G3DSA:3.40.50.10190 128 209 9.0E-10 T 13-09-2016 IPR001357 BRCT domain THL1_RS21085 c0c530f63cc9751c9f4e6887b04ee87e 214 SUPERFAMILY SSF52113 123 207 3.58E-5 T 13-09-2016 IPR001357 BRCT domain THL1_RS00810 cb75e6db6348bcc563bc93d89add1fcf 124 Gene3D G3DSA:3.10.450.50 4 123 4.2E-33 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS00810 cb75e6db6348bcc563bc93d89add1fcf 124 Pfam PF12893 Putative lumazine-binding 7 121 1.6E-33 T 13-09-2016 THL1_RS00810 cb75e6db6348bcc563bc93d89add1fcf 124 SUPERFAMILY SSF54427 6 124 2.92E-30 T 13-09-2016 IPR032710 NTF2-like domain THL1_RS07505 cf253b6b0caecc55fafeac3fdc4f478b 338 Pfam PF11927 Protein of unknown function (DUF3445) 55 293 1.6E-56 T 13-09-2016 IPR021848 Protein of unknown function DUF3445 THL1_RS07775 d91254f94a65f76ef31876c2560cedad 73 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 17 67 1.7E-7 T 13-09-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 THL1_RS02575 7eefc0921ed1648748e273b41a0238d0 521 PANTHER PTHR30029:SF2 6 509 1.8E-230 T 13-09-2016 THL1_RS02575 7eefc0921ed1648748e273b41a0238d0 521 Pfam PF04293 SpoVR like protein 16 447 8.3E-178 T 13-09-2016 IPR007390 Sporulation stage V, protein R THL1_RS02575 7eefc0921ed1648748e273b41a0238d0 521 PANTHER PTHR30029 6 509 1.8E-230 T 13-09-2016 THL1_RS17040 0f58bb1671247510d9445c05cea3c76c 649 Pfam PF11843 Protein of unknown function (DUF3363) 275 645 2.0E-138 T 13-09-2016 IPR021795 Protein of unknown function DUF3363 THL1_RS17550 54a59b902fac37b5208491e268096ed1 399 SUPERFAMILY SSF56349 63 378 1.02E-31 T 13-09-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THL1_RS17550 54a59b902fac37b5208491e268096ed1 399 Pfam PF00589 Phage integrase family 191 368 5.0E-9 T 13-09-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS17550 54a59b902fac37b5208491e268096ed1 399 Gene3D G3DSA:1.10.443.10 179 382 2.7E-19 T 13-09-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 THL1_RS06405 bcf18c320dd6189969f492d23ca96540 411 SUPERFAMILY SSF52317 53 141 8.01E-6 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS06405 bcf18c320dd6189969f492d23ca96540 411 SUPERFAMILY SSF52317 175 255 8.01E-6 T 13-09-2016 IPR029062 Class I glutamine amidotransferase-like THL1_RS06405 bcf18c320dd6189969f492d23ca96540 411 Pfam PF14258 Domain of unknown function (DUF4350) 46 111 4.2E-11 T 13-09-2016 IPR025646 Domain of unknown function DUF4350 THL1_RS16130 012a8e3132a1cab9ddcf638c6b1a92bd 176 Pfam PF06891 P2 phage tail completion protein R (GpR) 1 130 7.9E-46 T 13-09-2016 IPR009678 Bacteriophage tail completion protein R THL1_RS01135 b34f5d04d464e8b01db6f977927f1c22 610 Pfam PF02690 Na+/Pi-cotransporter 199 280 1.1E-9 T 13-09-2016 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: REACT_15518 THL1_RS01135 b34f5d04d464e8b01db6f977927f1c22 610 Pfam PF02690 Na+/Pi-cotransporter 36 174 7.4E-34 T 13-09-2016 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: REACT_15518 THL1_RS01135 b34f5d04d464e8b01db6f977927f1c22 610 PANTHER PTHR10010 28 477 2.4E-33 T 13-09-2016 THL1_RS01135 b34f5d04d464e8b01db6f977927f1c22 610 PANTHER PTHR10010:SF26 28 477 2.4E-33 T 13-09-2016 THL1_RS13195 f2ec3c4cd20867967b6f112c73276f13 627 Pfam PF06980 Protein of unknown function (DUF1302) 31 627 5.9E-217 T 13-09-2016 IPR010727 Protein of unknown function DUF1302 THL1_RS11280 fcb535bd4861024199e67c0a95ccdf8c 113 Gene3D G3DSA:3.30.70.970 6 105 2.3E-6 T 13-09-2016 IPR009671 Regulator of ribonuclease activity B domain THL1_RS11280 fcb535bd4861024199e67c0a95ccdf8c 113 Pfam PF06877 Regulator of ribonuclease activity B 8 104 2.6E-20 T 13-09-2016 IPR009671 Regulator of ribonuclease activity B domain THL1_RS11280 fcb535bd4861024199e67c0a95ccdf8c 113 SUPERFAMILY SSF89946 4 107 7.32E-25 T 13-09-2016 IPR009671 Regulator of ribonuclease activity B domain THL1_RS21820 8ae4b22cd787bcb21c2efb1d14a1e272 95 Pfam PF08734 GYD domain 4 91 1.0E-25 T 13-09-2016 IPR014845 Uncharacterised protein GYD THL1_RS04050 21fec373214659ecdb1c1db8ef4a8621 200 SUPERFAMILY SSF50494 19 179 1.39E-14 T 13-09-2016 IPR009003 Peptidase S1, PA clan THL1_RS04050 21fec373214659ecdb1c1db8ef4a8621 200 Gene3D G3DSA:2.40.10.10 96 177 7.2E-10 T 13-09-2016 THL1_RS02800 904e443f0d411b8464a6cec9bb5fae7a 445 PANTHER PTHR30569 4 439 3.7E-18 T 13-09-2016 IPR030191 Cytosine permease GO:0015209|GO:0016021 THL1_RS17740 040476cd49dff68b2cec31f59aa2db18 761 Pfam PF06934 Fatty acid cis/trans isomerase (CTI) 79 760 9.8E-283 T 13-09-2016 IPR010706 Fatty acid cis-trans isomerase THL1_RS18360 bf99b9a96f1c55d29469f6b65993ff59 55 Pfam PF11446 Protein of unknown function (DUF2897) 1 53 1.7E-25 T 13-09-2016 IPR021550 Protein of unknown function DUF2897 THL1_RS15365 7c6f7ab30e6910cb8d06cf4ddd58275c 206 Pfam PF01810 LysE type translocator 14 197 2.4E-26 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS15365 7c6f7ab30e6910cb8d06cf4ddd58275c 206 PANTHER PTHR30086:SF6 3 205 1.1E-39 T 13-09-2016 THL1_RS15365 7c6f7ab30e6910cb8d06cf4ddd58275c 206 PANTHER PTHR30086 3 205 1.1E-39 T 13-09-2016 IPR001123 Lysine-type exporter protein (LYSE/YGGA) GO:0006865|GO:0016020 THL1_RS00205 5b8e4dd3ff153e15e28de984ec6268cf 358 Pfam PF10023 Putative aminopeptidase 33 351 1.7E-134 T 13-09-2016 IPR014553 Predicted aminopeptidase THL1_RS00205 5b8e4dd3ff153e15e28de984ec6268cf 358 PIRSF PIRSF029285 6 357 1.4E-148 T 13-09-2016 IPR014553 Predicted aminopeptidase THL1_RS01225 20f3364fa64e605be9a75c7f48ff47ec 125 PANTHER PTHR10584 5 66 5.3E-18 T 13-09-2016 THL1_RS01225 20f3364fa64e605be9a75c7f48ff47ec 125 PANTHER PTHR10584:SF191 5 66 5.3E-18 T 13-09-2016 THL1_RS01225 20f3364fa64e605be9a75c7f48ff47ec 125 Pfam PF04241 Protein of unknown function (DUF423) 19 105 1.2E-28 T 13-09-2016 IPR006696 Protein of unknown function DUF423 THL1_RS16760 81f521eb38eed020d254f5e5fe838c17 102 Pfam PF03413 Peptidase propeptide and YPEB domain 41 98 2.0E-13 T 13-09-2016 IPR025711 PepSY domain THL1_RS10835 409fb9ad48b3e3303c008fffe91e387e 85 PANTHER PTHR36931 1 83 1.3E-34 T 13-09-2016 THL1_RS05820 65aa377023aa688c279b0fb105a83321 186 Pfam PF09335 SNARE associated Golgi protein 62 177 1.0E-16 T 13-09-2016 IPR032816 SNARE associated Golgi protein THL1_RS12780 89069e0c76121b7ff3339cb1930dffbf 292 Gene3D G3DSA:1.10.760.10 65 157 1.3E-14 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS12780 89069e0c76121b7ff3339cb1930dffbf 292 SUPERFAMILY SSF46626 17 174 2.18E-19 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS12780 89069e0c76121b7ff3339cb1930dffbf 292 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 69 150 3.2E-15 T 13-09-2016 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 THL1_RS01320 3e31c526ec5c87ec4deec702aec261c3 131 Pfam PF05154 TM2 domain 71 119 8.4E-15 T 13-09-2016 IPR007829 TM2 domain THL1_RS01320 3e31c526ec5c87ec4deec702aec261c3 131 Pfam PF05154 TM2 domain 8 54 2.7E-15 T 13-09-2016 IPR007829 TM2 domain THL1_RS01320 3e31c526ec5c87ec4deec702aec261c3 131 PANTHER PTHR21016 1 71 1.3E-25 T 13-09-2016 THL1_RS16085 b3316cbd18c2cb228d0554b43a5912d4 586 Pfam PF03237 Terminase-like family 162 569 3.2E-109 T 13-09-2016 IPR004921 Terminase, large subunit THL1_RS16085 b3316cbd18c2cb228d0554b43a5912d4 586 Pfam PF06056 Putative ATPase subunit of terminase (gpP-like) 12 68 2.8E-23 T 13-09-2016 IPR010332 ATPase terminase subunit, putative GO:0005524|GO:0019069 THL1_RS16755 80625fbe48a6b27fa2ebb94ca08e1085 104 Pfam PF03413 Peptidase propeptide and YPEB domain 42 101 5.9E-10 T 13-09-2016 IPR025711 PepSY domain THL1_RS16380 9b6f05326ba1e1729087de47b4103b81 246 Gene3D G3DSA:3.40.50.1000 134 233 2.9E-8 T 13-09-2016 IPR023214 HAD-like domain THL1_RS16380 9b6f05326ba1e1729087de47b4103b81 246 SUPERFAMILY SSF56784 10 235 3.2E-24 T 13-09-2016 IPR023214 HAD-like domain THL1_RS24740 d373da5944bbab30e1593c6c00b88404 282 Pfam PF03783 Curli production assembly/transport component CsgG 47 259 2.6E-78 T 13-09-2016 IPR005534 Curli production assembly/transport component CsgG GO:0030288 THL1_RS20130 a52542db56666b75735c25cc01f15a33 252 Pfam PF03988 Repeat of Unknown Function (DUF347) 10 61 3.9E-17 T 13-09-2016 IPR007136 Protein of unknown function DUF347 THL1_RS20130 a52542db56666b75735c25cc01f15a33 252 Pfam PF03988 Repeat of Unknown Function (DUF347) 130 181 3.1E-15 T 13-09-2016 IPR007136 Protein of unknown function DUF347 THL1_RS20130 a52542db56666b75735c25cc01f15a33 252 Pfam PF03988 Repeat of Unknown Function (DUF347) 65 114 5.6E-17 T 13-09-2016 IPR007136 Protein of unknown function DUF347 THL1_RS20130 a52542db56666b75735c25cc01f15a33 252 Pfam PF03988 Repeat of Unknown Function (DUF347) 185 237 4.4E-14 T 13-09-2016 IPR007136 Protein of unknown function DUF347 THL1_RS01255 2d9d935f0e2db1196f9081394b684cb7 107 Pfam PF11872 Protein of unknown function (DUF3392) 4 107 5.0E-40 T 13-09-2016 IPR021813 Protein of unknown function DUF3392 THL1_RS07960 584e83812b072b2ca364a18ec1e6446b 204 Pfam PF13699 Domain of unknown function (DUF4157) 82 162 4.2E-15 T 13-09-2016 IPR025295 Domain of unknown function DUF4157 THL1_RS10265 036f18352e3ec886f28c374e83520fd9 86 Pfam PF07023 Protein of unknown function (DUF1315) 6 66 1.1E-27 T 13-09-2016 IPR009749 Protein of unknown function DUF1315 THL1_RS16110 cf18ac142f9da52ee8a19f0c5e7344c5 68 Pfam PF05489 Phage Tail Protein X 3 57 2.6E-27 T 13-09-2016 IPR008861 Phage Tail Protein X-like THL1_RS23540 59210ec9fd18aa33a1241331e2010227 598 Pfam PF06980 Protein of unknown function (DUF1302) 31 598 1.4E-216 T 13-09-2016 IPR010727 Protein of unknown function DUF1302 THL1_RS18855 80076d4224b93bacb466f29a04b71b79 165 Pfam PF05751 FixH 11 152 3.9E-40 T 13-09-2016 IPR008620 Nitrogen fixation protein FixH THL1_RS23815 9f01795d0ea86a05a926acc8c6cc221c 86 Pfam PF09413 Putative prokaryotic signal transducing protein 1 66 1.1E-10 T 13-09-2016 IPR018551 Domain of unknown function DUF2007 THL1_RS16325 1e3bf9ce5a9e7329cbdf033ac423c06c 90 ProDom PD069311 TRANSCRIPTIONAL ACTIVATOR PRTN TRANSCRIPTION PYOCIN BIOSYNTHESIS DNA-BINDING BACTERIOCIN REGULATOR REGULATOR 2 73 5.0E-7 T 13-09-2016 IPR020518 Transcription regulator PrtN GO:0006355 THL1_RS16325 1e3bf9ce5a9e7329cbdf033ac423c06c 90 Pfam PF11112 Pyocin activator protein PrtN 3 77 1.7E-31 T 13-09-2016 IPR020518 Transcription regulator PrtN GO:0006355 THL1_RS11505 82c8afac70098e994eb991ae82476b96 169 Pfam PF06271 RDD family 26 161 1.6E-27 T 13-09-2016 IPR010432 RDD THL1_RS25420 765b6b13f56e5a3d2653e8732abfe53d 152 Pfam PF09980 Predicted membrane protein (DUF2214) 3 148 2.0E-52 T 13-09-2016 IPR018706 Protein of unknown function DUF2214, membrane THL1_RS09220 a3c4885d8740beda4f31c8c5a8081674 243 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 25 243 2.3E-30 T 13-09-2016 IPR010239 Conserved hypothetical protein CHP02001 THL1_RS09220 a3c4885d8740beda4f31c8c5a8081674 243 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 5 243 4.5E-45 T 13-09-2016 IPR010239 Conserved hypothetical protein CHP02001 THL1_RS25330 14e6c9c540342b9e8eeec7ce3485fd5b 300 PANTHER PTHR35007:SF2 1 298 6.9E-41 T 13-09-2016 THL1_RS25330 14e6c9c540342b9e8eeec7ce3485fd5b 300 Pfam PF00482 Type II secretion system (T2SS), protein F 158 284 5.9E-12 T 13-09-2016 IPR018076 Type II secretion system F domain THL1_RS25330 14e6c9c540342b9e8eeec7ce3485fd5b 300 PANTHER PTHR35007 1 298 6.9E-41 T 13-09-2016 THL1_RS12420 9c47c82aa5c325e6208d0620e36ab60c 124 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 118 6.8E-25 T 13-09-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 THL1_RS12420 9c47c82aa5c325e6208d0620e36ab60c 124 PANTHER PTHR28259 5 124 3.0E-33 T 13-09-2016 THL1_RS12420 9c47c82aa5c325e6208d0620e36ab60c 124 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 5 123 19.129 T 13-09-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 THL1_RS12420 9c47c82aa5c325e6208d0620e36ab60c 124 TIGRFAM TIGR00494 crcB: protein CrcB 6 121 6.0E-24 T 13-09-2016 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 THL1_RS25400 3a34b992daaebba3673307dfb91fd81f 264 PIRSF PIRSF029691 1 264 1.1E-84 T 13-09-2016 IPR016934 Uncharacterised conserved protein UCP029691 THL1_RS06825 ec75c8585e5755062278bcbf1f4d00e5 72 Pfam PF09834 Predicted membrane protein (DUF2061) 1 52 2.4E-21 T 13-09-2016 IPR018638 Domain of unknown function DUF2061, membrane THL1_RS09560 d751b248eb54c63fc48f814b04a1b625 172 Pfam PF01478 Type IV leader peptidase family 11 112 1.7E-13 T 13-09-2016 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 THL1_RS25620 af60dc4f50c2666d97ee9b1965c4625f 112 Pfam PF04355 SmpA / OmlA family 30 96 6.0E-16 T 13-09-2016 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 THL1_RS23490 839fce22d88c28a62ac28cd70cace433 103 Pfam PF12021 Protein of unknown function (DUF3509) 5 84 1.2E-24 T 13-09-2016 IPR021898 Protein of unknown function DUF3509 THL1_RS16400 eee9bb9f20ada7dbfa0ac8e3030ae8cf 255 Pfam PF13835 Domain of unknown function (DUF4194) 55 222 2.4E-26 T 13-09-2016 IPR025449 Protein of unknown function DUF4194 THL1_RS10975 42622d43dd6aef19c173125361286a58 257 PANTHER PTHR31040 10 242 3.1E-52 T 13-09-2016 THL1_RS08625 2e46f775d633f4375d570e91a915eaee 94 Pfam PF10976 Protein of unknown function (DUF2790) 11 85 1.1E-23 T 13-09-2016 IPR021245 Protein of unknown function DUF2790 THL1_RS10455 b9f86e6a1fa5af1fde99d2d40c5eb204 597 Pfam PF06048 Domain of unknown function (DUF927) 44 314 6.8E-78 T 13-09-2016 IPR009270 Domain of unknown function DUF927 THL1_RS11875 b2a078ae11bedfca833e7424ffd9b202 334 Pfam PF13557 Putative MetA-pathway of phenol degradation 87 322 2.3E-7 T 13-09-2016 IPR025737 MetA-pathway of phenol degradation, putative THL1_RS16100 47f53d17ca58b64144323458fd2214b5 232 Pfam PF05944 Phage small terminase subunit 37 166 1.5E-51 T 13-09-2016 IPR010270 Bacteriophage P2, GpM GO:0003677|GO:0004519|GO:0019069 THL1_RS05455 b9796f1f6af909dc7fb14be78cf1f2e1 213 Pfam PF10670 Domain of unknown function (DUF4198) 20 212 1.0E-19 T 13-09-2016 IPR019613 Protein of unknown function DUF4198 THL1_RS13545 1c83f32d2b1b59052e9872dd003cc138 133 Pfam PF09722 Protein of unknown function (DUF2384) 79 133 3.3E-10 T 13-09-2016 IPR024467 Domain of unknown function DUF2384 THL1_RS13545 1c83f32d2b1b59052e9872dd003cc138 133 ProDom PD080812 PLASMID Y4OB BMEII097 AGR_L_107P MLL2216 BMEII0977 ATU4831 22 128 2.0E-34 T 13-09-2016 IPR020358 Uncharacterised protein family Y4oB THL1_RS01440 75b5b2bef804b6eaef6c00b5837aa626 307 Gene3D G3DSA:2.120.10.30 72 293 4.7E-14 T 13-09-2016 IPR011042 Six-bladed beta-propeller, TolB-like THL1_RS01440 75b5b2bef804b6eaef6c00b5837aa626 307 Pfam PF06977 SdiA-regulated 51 302 1.8E-105 T 13-09-2016 IPR009722 SdiA-regulated THL1_RS01440 75b5b2bef804b6eaef6c00b5837aa626 307 SUPERFAMILY SSF50956 14 303 9.81E-53 T 13-09-2016 THL1_RS05830 27bc8d412231fa4c8fe70464eb10127d 98 Pfam PF09904 Winged helix-turn helix 5 95 8.1E-40 T 13-09-2016 IPR017162 Uncharacterised conserved protein UCP037266 THL1_RS05830 27bc8d412231fa4c8fe70464eb10127d 98 PIRSF PIRSF037266 1 98 7.6E-45 T 13-09-2016 IPR017162 Uncharacterised conserved protein UCP037266 THL1_RS20100 3aa5460bd77e21f5def7175b734a5b26 296 Pfam PF04228 Putative neutral zinc metallopeptidase 26 288 3.3E-47 T 13-09-2016 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative THL1_RS20100 3aa5460bd77e21f5def7175b734a5b26 296 PANTHER PTHR30168 13 296 4.3E-43 T 13-09-2016 THL1_RS15385 148fdf671531bf62978c582b6f8fdaaa 384 Gene3D G3DSA:2.130.10.10 22 382 1.4E-126 T 13-09-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 THL1_RS15385 148fdf671531bf62978c582b6f8fdaaa 384 Pfam PF06433 Methylamine dehydrogenase heavy chain (MADH) 46 381 7.2E-50 T 13-09-2016 IPR009451 Amine dehydrogenase heavy chain GO:0030058|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 THL1_RS15385 148fdf671531bf62978c582b6f8fdaaa 384 SUPERFAMILY SSF50969 38 374 1.31E-78 T 13-09-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like THL1_RS13910 89d2830c7d2697c561b5585f1249b577 336 Pfam PF03601 Conserved hypothetical protein 698 18 316 3.5E-72 T 13-09-2016 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 THL1_RS13910 89d2830c7d2697c561b5585f1249b577 336 PANTHER PTHR30106 3 336 2.5E-59 T 13-09-2016 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 THL1_RS10280 41a02a3bf79295c406598ea40cf904c0 678 Pfam PF06980 Protein of unknown function (DUF1302) 40 678 6.6E-182 T 13-09-2016 IPR010727 Protein of unknown function DUF1302 THL1_RS00540 e7320c0436b5df285d91bd4964390ded 588 Pfam PF06980 Protein of unknown function (DUF1302) 31 588 3.2E-222 T 13-09-2016 IPR010727 Protein of unknown function DUF1302 THL1_RS22755 75760d834de43c4ffa3b66942de4c903 225 Pfam PF13852 Protein of unknown function (DUF4197) 25 223 2.9E-76 T 13-09-2016 IPR025245 Protein of unknown function DUF4197 THL1_RS20400 6c6fdb2db86d772ffc8c8b163884c05f 83 Pfam PF05598 Transposase domain (DUF772) 51 76 4.8E-7 T 13-09-2016 IPR008490 Transposase InsH, N-terminal THL1_RS16695 6c2826d804cfdde0928767bb356e9a5f 235 Pfam PF11740 Plasmid replication region DNA-binding N-term 7 114 1.4E-16 T 13-09-2016 IPR021104 KfrA, N-terminal DNA-binding domain THL1_RS24725 f83bd8cc12b6eca45000bce4ae184f1f 156 Pfam PF07012 Curlin associated repeat 73 102 2.1E-4 T 13-09-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 THL1_RS24725 f83bd8cc12b6eca45000bce4ae184f1f 156 Pfam PF07012 Curlin associated repeat 93 124 9.0E-7 T 13-09-2016 IPR009742 Curlin associated GO:0007155|GO:0009289 THL1_RS06410 d0e06ba2f4b0846ccec22792f10c66de 527 Pfam PF13559 Domain of unknown function (DUF4129) 447 518 6.4E-8 T 13-09-2016 IPR025403 Domain of unknown function DUF4129 THL1_RS27490 33b5f1c14683bef26a87959ea5d24d7c 46 Pfam PF13627 Prokaryotic lipoprotein-attachment site 9 30 5.2E-11 T 13-09-2016 IPR032831 Prokaryotic lipoprotein-attachment site THL1_RS02415 c6db3ff4c2277216e3420f926d04b29c 583 Pfam PF08309 LVIVD repeat 366 395 0.0026 T 13-09-2016 IPR013211 LVIVD THL1_RS11145 0017b5e8883dffd9db9ce88aa8376278 168 SUPERFAMILY SSF50891 55 165 7.96E-14 T 13-09-2016 IPR029000 Cyclophilin-like domain THL1_RS15505 a81a934750b6c32135467f4c046dddb3 189 Pfam PF07291 Methylamine utilisation protein MauE 5 176 7.6E-14 T 13-09-2016 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 UniPathway: UPA00895 THL1_RS03810 06ab8919fe91d4a448823c59cb62a5b5 188 Pfam PF10986 Protein of unknown function (DUF2796) 33 184 1.2E-52 T 13-09-2016 IPR021253 Protein of unknown function DUF2796 THL1_RS06965 77657e18a38c1e5786ad9ac067e63676 169 Pfam PF09832 Uncharacterized protein conserved in bacteria (DUF2059) 90 149 1.1E-22 T 13-09-2016 IPR018637 Domain of unknown function DUF2059 THL1_RS18840 a599cd0d8feff428d341baaf8aefa5ff 62 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 9 45 1.6E-12 T 13-09-2016 IPR008621 Cbb3-type cytochrome oxidase component THL1_RS10390 69dc53a6c6a5c1c65e61b06ab384766c 354 Pfam PF13515 Fusaric acid resistance protein-like 206 329 6.3E-18 T 13-09-2016 THL1_RS16135 39b070b6bcfc740bf1195ac97a645b98 151 Pfam PF05069 Phage virion morphogenesis family 4 148 2.0E-41 T 13-09-2016 IPR006522 Phage virion morphogensis protein THL1_RS16135 39b070b6bcfc740bf1195ac97a645b98 151 TIGRFAM TIGR01635 tail_comp_S: phage virion morphogenesis protein 5 147 1.5E-36 T 13-09-2016 IPR006522 Phage virion morphogensis protein THL1_RS17630 2edd559a9be8abfb88684e5ef6deb242 110 Gene3D G3DSA:1.10.10.60 65 97 3.6E-5 T 13-09-2016 IPR009057 Homeodomain-like GO:0003677 THL1_RS26630 79225f4d6e29999d856fe3dcdc846229 674 Pfam PF04830 Possible hemagglutinin (DUF637) 160 334 1.4E-35 T 13-09-2016 IPR006915 Domain of unknown function DUF637, haemagglutinin putative THL1_RS20250 156a493c316252f8014dbb15a5211b96 68 Pfam PF07869 Protein of unknown function (DUF1656) 5 60 7.1E-22 T 13-09-2016 IPR012451 Protein of unknown function DUF1656 THL1_RS03115 ae7430957a3f12f31c4bfaf8fb683623 456 Pfam PF04932 O-Antigen ligase 220 371 2.1E-17 T 13-09-2016 IPR007016 O-antigen ligase-related THL1_RS13780 9b02e5088f2e999fd1a5ebddd7e84672 272 Pfam PF10703 Molybdenum cofactor biosynthesis protein F 5 269 4.4E-105 T 13-09-2016 IPR024724 Molybdenum cofactor biosynthesis protein F THL1_RS16255 3f65674ae513d976e61ad3966141c819 302 Pfam PF10987 Protein of unknown function (DUF2806) 63 285 8.3E-32 T 13-09-2016 IPR021254 Protein of unknown function DUF2806 THL1_RS04780 7f19a51c9f04bb87a2689bdc6ecae980 617 Pfam PF13387 Domain of unknown function (DUF4105) 118 290 2.8E-62 T 13-09-2016 IPR025178 Domain of unknown function DUF4105 THL1_RS13130 d9c134dd773a532d40f894d8ebbc4a02 245 Pfam PF10099 Anti-sigma-K factor rskA 66 240 4.7E-25 T 13-09-2016 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 THL1_RS26605 84449bcb3f26e3df50354befed1fa23b 131 Pfam PF03692 Putative zinc- or iron-chelating domain 25 125 9.8E-14 T 13-09-2016 IPR005358 Putative zinc- or iron-chelating domain containing protein THL1_RS20810 887b2c3b81f546362c9cc728f4d1c856 89 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 11 81 2.1E-13 T 13-09-2016 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 THL1_RS18510 ffe8cd43f9c8f520d66e7c170b83dcf9 118 Pfam PF07238 PilZ domain 17 106 1.4E-13 T 13-09-2016 IPR009875 PilZ domain GO:0035438 THL1_RS23190 2a2f451d26486726fe2042aea885ec08 196 Gene3D G3DSA:3.40.630.30 14 165 4.1E-10 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS23190 2a2f451d26486726fe2042aea885ec08 196 SUPERFAMILY SSF55729 12 190 8.83E-12 T 13-09-2016 IPR016181 Acyl-CoA N-acyltransferase THL1_RS00360 0101694ef935d100b73ace89780c622b 93 Pfam PF11191 Protein of unknown function (DUF2782) 21 93 5.0E-25 T 13-09-2016 IPR021357 Protein of unknown function DUF2782 THL1_RS11710 c7b696b6744108fa06e2b3ef9c443f7a 119 Pfam PF06127 Protein of unknown function (DUF962) 12 45 1.3E-5 T 13-09-2016 IPR009305 Protein of unknown function DUF962 THL1_RS24355 67bc0cac738bd6a5d0a92501ab7fa821 96 Pfam PF11006 Protein of unknown function (DUF2845) 20 93 8.1E-19 T 13-09-2016 IPR021268 Protein of unknown function DUF2845 THL1_RS03220 2ca7967e58d9f6cac3371f285e18af2d 309 Pfam PF13557 Putative MetA-pathway of phenol degradation 64 305 1.6E-59 T 13-09-2016 IPR025737 MetA-pathway of phenol degradation, putative THL1_RS26910 2759884ab5097f6f5e56966c7e0b317f 268 TIGRFAM TIGR04255 sporadTIGR04255: TIGR04255 family protein 4 266 5.1E-42 T 13-09-2016 IPR026349 Conserved hypothetical protein CHP04255 THL1_RS09730 cfb10c94d8a7bb9f8694193bcefb506f 200 SUPERFAMILY SSF52343 23 151 5.44E-6 T 13-09-2016 THL1_RS20315 3f69fac6fd51497519da9bd1af2dea71 314 Pfam PF09828 Chromate resistance exported protein 178 304 5.8E-44 T 13-09-2016 IPR018634 Chromate resistance exported protein THL1_RS20310 0296c904c823c3a2fa1a316c9a4731f2 167 Pfam PF09933 Predicted small integral membrane protein (DUF2165) 2 157 3.3E-62 T 13-09-2016 IPR018681 Protein of unknown function DUF2165, transmembrane THL1_RS02570 efcd36c60485826fcc3cc382195fb63c 169 Pfam PF13590 Domain of unknown function (DUF4136) 57 166 1.3E-9 T 13-09-2016 IPR025411 Domain of unknown function DUF4136 THL1_RS28375 cc60e167ed90cba455b3c71385e6f0d9 214 Pfam PF08856 Protein of unknown function (DUF1826) 16 211 1.4E-63 T 13-09-2016 IPR014955 Protein of unknown function DUF1826 THL1_RS04665 54819519e00a5b6a6734d6ca3fc5f71b 46 Pfam PF10617 Protein of unknown function (DUF2474) 7 45 9.6E-21 T 13-09-2016 IPR018895 Protein of unknown function DUF2474 THL1_RS14320 3be8fd66a003605545aec89e488afd69 258 Pfam PF09836 Putative DNA-binding domain 4 93 1.3E-22 T 13-09-2016 IPR018640 Putative DNA-binding domain, bacteria THL1_RS23950 9f54361a707c07b8c338f299b7420777 166 Pfam PF11086 Protein of unknown function (DUF2878) 5 153 3.9E-38 T 13-09-2016 IPR021306 Protein of unknown function DUF2878 THL1_RS08960 47485b7f8976f20250cbb6f7b127022f 199 Pfam PF06930 Protein of unknown function (DUF1282) 8 179 1.2E-59 T 13-09-2016 IPR009698 Protein of unknown function DUF1282 THL1_RS08550 52cb32ef4b1e8d5038049deadc1ee8dc 122 Pfam PF16703 Domain of unknown function (DUF5064) 1 117 2.7E-50 T 13-09-2016 IPR032024 Protein of unknown function DUF5064 THL1_RS05050 a5a112d48d622e4cc422c4bef65a3d25 229 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 208 7.0E-17 T 13-09-2016 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 UniPathway: UPA00148 THL1_RS09595 e2562a3ca30b6b80235b7d4dca0f75ca 167 Pfam PF07811 TadE-like protein 8 50 4.7E-9 T 13-09-2016 IPR012495 TadE-like THL1_RS02230 89c668a05d3cee590e3c4d30060840d3 150 Pfam PF13441 YMGG-like Gly-zipper 60 117 2.1E-7 T 13-09-2016 IPR027367 YMGG-like Gly-zipper THL1_RS26595 5d7a717d57defe83960ed46e61ac0207 461 Gene3D G3DSA:2.60.120.260 156 236 9.8E-5 T 13-09-2016 IPR008979 Galactose-binding domain-like THL1_RS26595 5d7a717d57defe83960ed46e61ac0207 461 Pfam PF13163 Protein of unknown function (DUF3999) 32 453 6.4E-148 T 13-09-2016 IPR025060 Protein of unknown function DUF3999 THL1_RS13970 d84b3043837229002f0b828fe6927b1f 134 Gene3D G3DSA:1.10.1270.10 35 72 8.5E-4 T 13-09-2016 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 THL1_RS13640 42df175f53d3739517b10fc651df68ab 102 Pfam PF11127 Protein of unknown function (DUF2892) 13 69 1.9E-9 T 13-09-2016 IPR021309 Protein of unknown function DUF2892 THL1_RS21300 9c69e8025118ae8ee13692d0c1d34cb9 125 Pfam PF16137 Domain of unknown function (DUF4845) 31 116 3.8E-21 T 13-09-2016 IPR032314 Protein of unknown function DUF4845 THL1_RS25615 8cfcc2d452ba6d8d4adfcb486ef2497b 122 Pfam PF04355 SmpA / OmlA family 30 96 8.0E-15 T 13-09-2016 IPR007450 Lipoprotein SmpA/OmlA GO:0019867