locus-tag	class	description
IF103_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IF103_RS00010	COG0592	DNA-directed DNA polymerase activity
IF103_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IF103_RS00020	COG0187	DNA topoisomerase II activity
IF103_RS00075	COG0583	DNA-binding transcription factor activity
IF103_RS00125	COG0583	DNA-binding transcription factor activity
IF103_RS00140	COG2843	Capsule synthesis protein
IF103_RS00180	COG0477	Major facilitator Superfamily
IF103_RS00190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IF103_RS00195	COG0751	glycine-tRNA ligase activity
IF103_RS00200	COG0752	glycyl-tRNA synthetase alpha subunit
IF103_RS00205	COG2818	Glycosylase
IF103_RS00220	COG0569	domain protein
IF103_RS00225	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IF103_RS00230	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IF103_RS00235	COG0242	peptide deformylase activity
IF103_RS00240	COG0758	DNA mediated transformation
IF103_RS00245	COG0009	L-threonylcarbamoyladenylate synthase
IF103_RS00255	COG0408	coproporphyrinogen oxidase activity
IF103_RS00260	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IF103_RS00265	COG0659	secondary active sulfate transmembrane transporter activity
IF103_RS00275	COG3119	arylsulfatase activity
IF103_RS00280	COG0583	DNA-binding transcription factor activity
IF103_RS00290	COG0159	tryptophan synthase activity
IF103_RS00295	COG0133	tryptophan synthase activity
IF103_RS00310	COG3360	Dodecin
IF103_RS00320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IF103_RS00325	COG1764	response to oxidative stress
IF103_RS00355	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IF103_RS00360	COG0339	signal peptide processing
IF103_RS00365	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IF103_RS00385	COG0659	secondary active sulfate transmembrane transporter activity
IF103_RS00395	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IF103_RS00400	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IF103_RS00405	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
IF103_RS00430	COG1612	heme a metabolic process
IF103_RS00435	COG0109	protoheme IX farnesyltransferase activity
IF103_RS00450	COG2011	ABC-type metal ion transport system permease component
IF103_RS00455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IF103_RS00470	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IF103_RS00475	COG1121	(ABC) transporter
IF103_RS00480	COG0735	belongs to the Fur family
IF103_RS00485	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IF103_RS00505	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IF103_RS00510	COG3245	cytochrome
IF103_RS00520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IF103_RS00540	COG3023	N-Acetylmuramoyl-L-alanine amidase
IF103_RS00545	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IF103_RS00550	COG5002	protein histidine kinase activity
IF103_RS00555	COG2204	response regulator
IF103_RS00580	COG1301	dicarboxylic acid transport
IF103_RS00585	COG0700	Nucleoside recognition
IF103_RS00600	COG1127	ABC transporter
IF103_RS00605	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IF103_RS00620	COG1283	sodium-dependent phosphate transmembrane transporter activity
IF103_RS00625	COG0861	Integral membrane protein TerC family
IF103_RS00630	COG2851	Citrate transporter
IF103_RS00665	COG0427	acetyl-CoA hydrolase
IF103_RS00685	COG0583	DNA-binding transcription factor activity
IF103_RS00690	COG1960	acyl-CoA dehydrogenase activity
IF103_RS00755	COG1802	Transcriptional regulator
IF103_RS00765	COG2199	diguanylate cyclase activity
IF103_RS00765	COG2200	EAL domain
IF103_RS00765	COG3287	FIST C domain
IF103_RS00815	COG1215	transferase activity, transferring glycosyl groups
IF103_RS00820	COG1215	transferase activity, transferring glycosyl groups
IF103_RS00825	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
IF103_RS00830	COG3118	belongs to the thioredoxin family
IF103_RS00830	COG0457	Tetratricopeptide repeat
IF103_RS00835	COG2175	clavaminate synthase activity
IF103_RS00850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IF103_RS00870	COG1335	isochorismatase
IF103_RS00875	COG4191	Histidine kinase
IF103_RS00880	COG4566	intracellular signal transduction
IF103_RS00885	COG4566	intracellular signal transduction
IF103_RS00895	COG0606	chelatase, subunit chli
IF103_RS00915	COG0347	Belongs to the P(II) protein family
IF103_RS00920	COG0004	ammonium transporteR
IF103_RS00930	COG0546	phosphoglycolate phosphatase activity
IF103_RS00935	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IF103_RS00945	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IF103_RS00950	COG0019	diaminopimelate decarboxylase activity
IF103_RS00960	COG1965	Belongs to the frataxin family
IF103_RS00970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IF103_RS00975	COG3072	Adenylate cyclase
IF103_RS00990	COG0625	glutathione transferase activity
IF103_RS00995	COG0165	Argininosuccinate lyase
IF103_RS01005	COG0181	hydroxymethylbilane synthase activity
IF103_RS01025	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IF103_RS01050	COG0488	(ABC) transporter
IF103_RS01060	COG1280	lysine exporter protein (LysE YggA)
IF103_RS01090	COG0517	IMP dehydrogenase activity
IF103_RS01100	COG1012	belongs to the aldehyde dehydrogenase family
IF103_RS01105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IF103_RS01115	COG2199	diguanylate cyclase activity
IF103_RS01130	COG2011	ABC-type metal ion transport system permease component
IF103_RS01135	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IF103_RS01160	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IF103_RS01165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IF103_RS01180	COG0494	nUDIX hydrolase
IF103_RS01185	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
IF103_RS01195	COG0730	response to heat
IF103_RS01200	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IF103_RS01205	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IF103_RS01210	COG0789	Transcriptional regulator
IF103_RS01220	COG0583	DNA-binding transcription factor activity
IF103_RS01225	COG3842	ATPase activity
IF103_RS01230	COG1178	ABC-type Fe3 transport system permease component
IF103_RS01235	COG1840	ABC-type Fe3 transport system, periplasmic component
IF103_RS01245	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IF103_RS01260	COG1823	symporter activity
IF103_RS01270	COG0129	dihydroxy-acid dehydratase activity
IF103_RS01275	COG2239	Acts as a magnesium transporter
IF103_RS01280	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IF103_RS01290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IF103_RS01295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IF103_RS01300	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IF103_RS01320	COG1309	transcriptional regulator
IF103_RS01340	COG0612	Peptidase, M16
IF103_RS01345	COG0742	ribosomal rna small subunit methyltransferase
IF103_RS01350	COG0612	Peptidase, M16
IF103_RS01355	COG0612	Peptidase, M16
IF103_RS01360	COG0552	protein localization to endoplasmic reticulum
IF103_RS01365	COG2884	Cell division ATP-binding protein ftsE
IF103_RS01370	COG2177	Part of the ABC transporter FtsEX involved in
IF103_RS01380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IF103_RS01385	COG2363	Small membrane protein
IF103_RS01390	COG2022	thiamine diphosphate biosynthetic process
IF103_RS01390	COG2104	thiamine diphosphate biosynthetic process
IF103_RS01395	COG2022	thiamine diphosphate biosynthetic process
IF103_RS01400	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IF103_RS01410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IF103_RS01415	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IF103_RS01425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IF103_RS01425	COG2813	Specifically methylates the guanine in position
IF103_RS01430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IF103_RS01455	COG0791	NLP P60 protein
IF103_RS01470	COG0018	arginyl-trna synthetase
IF103_RS01475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IF103_RS01480	COG0254	rRNA binding
IF103_RS01490	COG0281	malic enzyme
IF103_RS01520	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IF103_RS01525	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IF103_RS01535	COG0070	glutamate synthase
IF103_RS01535	COG0067	glutamate synthase
IF103_RS01535	COG0069	glutamate synthase activity
IF103_RS01540	COG0493	'glutamate synthase
IF103_RS01545	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IF103_RS01565	COG2814	Major facilitator Superfamily
IF103_RS01570	COG0583	DNA-binding transcription factor activity
IF103_RS01575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IF103_RS01580	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS01615	COG2986	histidine ammonia-lyase
IF103_RS01630	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IF103_RS01640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IF103_RS01660	COG1192	Involved in chromosome partitioning
IF103_RS01665	COG3118	belongs to the thioredoxin family
IF103_RS01670	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IF103_RS01675	COG1196	nuclear chromosome segregation
IF103_RS01675	COG3264	Mechanosensitive ion channel
IF103_RS01680	COG3263	regulation of cellular component size
IF103_RS01685	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IF103_RS01690	COG1012	belongs to the aldehyde dehydrogenase family
IF103_RS01695	COG1309	transcriptional regulator
IF103_RS01700	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IF103_RS01710	COG2861	carbohydrate metabolic process
IF103_RS01715	COG0793	Belongs to the peptidase S41A family
IF103_RS01720	COG4942	peptidase
IF103_RS01725	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IF103_RS01740	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IF103_RS01745	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IF103_RS01765	COG3852	Histidine kinase
IF103_RS01780	COG0301	tRNA thio-modification
IF103_RS01780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IF103_RS01785	COG1217	gtp-binding protein TYPA
IF103_RS01795	COG0058	SHG alpha-glucan phosphorylase activity
IF103_RS01800	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IF103_RS01825	COG0402	S-adenosylhomocysteine deaminase activity
IF103_RS01830	COG2188	Transcriptional regulator
IF103_RS01840	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IF103_RS01850	COG4176	ABC-type proline glycine betaine transport system permease component
IF103_RS01855	COG4175	Glycine betaine
IF103_RS01855	COG0517	IMP dehydrogenase activity
IF103_RS01860	COG2986	histidine ammonia-lyase
IF103_RS01865	COG2986	histidine ammonia-lyase
IF103_RS01870	COG1228	amidohydrolase
IF103_RS01890	COG1490	D-aminoacyl-tRNA deacylase activity
IF103_RS01895	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
IF103_RS01900	COG2943	transferase activity, transferring hexosyl groups
IF103_RS01910	COG0765	amino acid transport
IF103_RS01915	COG1126	abc transporter atp-binding protein
IF103_RS01920	COG0840	transmembrane signaling receptor activity
IF103_RS01925	COG0840	transmembrane signaling receptor activity
IF103_RS01940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IF103_RS01945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IF103_RS01950	COG0140	phosphoribosyl-ATP diphosphatase activity
IF103_RS01955	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IF103_RS01960	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IF103_RS01970	COG2226	methyltransferase
IF103_RS02015	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IF103_RS02020	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IF103_RS02025	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IF103_RS02030	COG0540	Belongs to the ATCase OTCase family
IF103_RS02035	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IF103_RS02040	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IF103_RS02045	COG1678	Uncharacterized ACR, COG1678
IF103_RS02055	COG0189	ligase activity
IF103_RS02080	COG0784	Response regulator, receiver
IF103_RS02080	COG0643	Histidine kinase
IF103_RS02080	COG2198	Histidine kinase
IF103_RS02090	COG1272	protein, Hemolysin III
IF103_RS02095	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IF103_RS02110	COG3038	cytochrome b561
IF103_RS02115	COG2353	YceI-like domain
IF103_RS02120	COG0513	Belongs to the DEAD box helicase family
IF103_RS02135	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IF103_RS02140	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IF103_RS02180	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IF103_RS02185	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IF103_RS02190	COG4106	trans-aconitate 2-methyltransferase activity
IF103_RS02195	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IF103_RS02200	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IF103_RS02205	COG0126	phosphoglycerate kinase activity
IF103_RS02230	COG1451	nucleotide metabolic process
IF103_RS02245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IF103_RS02260	COG1289	transmembrane transporter activity
IF103_RS02265	COG2081	HI0933 family
IF103_RS02270	COG0513	Belongs to the DEAD box helicase family
IF103_RS02275	COG0477	Major facilitator Superfamily
IF103_RS02300	COG1960	acyl-CoA dehydrogenase activity
IF103_RS02305	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IF103_RS02305	COG0506	proline dehydrogenase activity
IF103_RS02305	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IF103_RS02310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IF103_RS02315	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IF103_RS02320	COG2192	nodulation
IF103_RS02325	COG0438	transferase activity, transferring glycosyl groups
IF103_RS02350	COG0438	transferase activity, transferring glycosyl groups
IF103_RS02365	COG1132	(ABC) transporter
IF103_RS02370	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IF103_RS02370	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IF103_RS02380	COG0667	Aldo Keto reductase
IF103_RS02400	COG1519	Transferase
IF103_RS02405	COG1538	Outer membrane efflux protein
IF103_RS02410	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IF103_RS02425	COG0494	nUDIX hydrolase
IF103_RS02435	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IF103_RS02440	COG3150	esterase
IF103_RS02455	COG3577	Aspartyl protease
IF103_RS02475	COG3830	Belongs to the UPF0237 family
IF103_RS02475	COG0560	Phosphoserine phosphatase
IF103_RS02485	COG0688	phosphatidylethanolamine metabolic process
IF103_RS02500	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IF103_RS02510	COG1162	GTPase activity
IF103_RS02515	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IF103_RS02520	COG2860	membrane
IF103_RS02530	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IF103_RS02530	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IF103_RS02535	COG0802	atpase or kinase
IF103_RS02540	COG0860	N-Acetylmuramoyl-L-alanine amidase
IF103_RS02545	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IF103_RS02550	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IF103_RS02555	COG1923	regulation of RNA biosynthetic process
IF103_RS02560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IF103_RS02565	COG0330	HflC and HflK could
IF103_RS02570	COG0330	HflC and HflK could
IF103_RS02575	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IF103_RS02580	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IF103_RS02585	COG0840	transmembrane signaling receptor activity
IF103_RS02590	COG2197	response regulator
IF103_RS02595	COG3916	Acyl-homoserine-lactone synthase
IF103_RS02600	COG2249	NAD(P)H dehydrogenase (quinone) activity
IF103_RS02615	COG1902	pentaerythritol trinitrate reductase activity
IF103_RS02615	COG0446	pyridine nucleotide-disulphide oxidoreductase
IF103_RS02620	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS02635	COG1178	ABC-type Fe3 transport system permease component
IF103_RS02640	COG1840	ABC-type Fe3 transport system, periplasmic component
IF103_RS02655	COG0557	exoribonuclease II activity
IF103_RS02660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IF103_RS02665	COG0360	Binds together with S18 to 16S ribosomal RNA
IF103_RS02670	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IF103_RS02680	COG0359	binds to the 23S rRNA
IF103_RS02685	COG0305	Participates in initiation and elongation during chromosome replication
IF103_RS02690	COG5265	(ABC) transporter
IF103_RS02705	COG1032	radical SAM domain protein
IF103_RS02720	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IF103_RS02725	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IF103_RS02755	COG4221	oxidoreductase activity
IF103_RS02775	COG2982	Protein involved in outer membrane biogenesis
IF103_RS02790	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IF103_RS02805	COG0443	Heat shock 70 kDa protein
IF103_RS02810	COG0484	heat shock protein binding
IF103_RS02815	COG0789	Transcriptional regulator
IF103_RS02830	COG0411	ABC transporter
IF103_RS02850	COG1113	amino acid transport
IF103_RS02885	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
IF103_RS02895	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IF103_RS02925	COG2095	MarC family integral membrane protein
IF103_RS02935	COG0151	Belongs to the GarS family
IF103_RS02940	COG0138	bifunctional purine biosynthesis protein purh
IF103_RS02950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IF103_RS02960	COG2264	protein methyltransferase activity
IF103_RS02965	COG2951	lytic endotransglycosylase activity
IF103_RS02985	COG0495	leucyl-tRNA aminoacylation
IF103_RS03000	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IF103_RS03005	COG4535	Mg2 and Co2 transporter CorC
IF103_RS03010	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IF103_RS03015	COG1702	phosphate starvation-inducible protein PhoH
IF103_RS03030	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IF103_RS03035	COG0352	thiamine-phosphate diphosphorylase activity
IF103_RS03040	COG0351	phosphomethylpyrimidine kinase
IF103_RS03045	COG2205	protein histidine kinase activity
IF103_RS03045	COG3850	Histidine kinase
IF103_RS03045	COG4999	Histidine kinase
IF103_RS03045	COG3437	response regulator, receiver
IF103_RS03050	COG1960	acyl-CoA dehydrogenase activity
IF103_RS03055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IF103_RS03070	COG1522	sequence-specific DNA binding
IF103_RS03090	COG1643	Atp-dependent helicase
IF103_RS03100	COG3416	Protein conserved in bacteria
IF103_RS03110	COG1522	sequence-specific DNA binding
IF103_RS03115	COG0697	spore germination
IF103_RS03120	COG0513	Belongs to the DEAD box helicase family
IF103_RS03130	COG0123	including yeast histone deacetylase and acetoin utilization protein
IF103_RS03145	COG1946	Acyl-CoA thioesterase
IF103_RS03150	COG0546	phosphoglycolate phosphatase activity
IF103_RS03155	COG1064	alcohol dehydrogenase
IF103_RS03250	COG1401	restriction endodeoxyribonuclease activity
IF103_RS03250	COG1401	restriction endodeoxyribonuclease activity
IF103_RS03265	COG1002	Type II restriction enzyme, methylase subunits
IF103_RS03270	COG1061	Type III restriction enzyme res subunit
IF103_RS03275	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IF103_RS03300	COG4983	Phage plasmid primase, P4 family domain protein
IF103_RS03325	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IF103_RS03330	COG0582	viral genome integration into host DNA
IF103_RS03350	COG1304	FMN binding
IF103_RS03355	COG1620	l-lactate permease
IF103_RS03360	COG2186	Transcriptional regulator
IF103_RS03365	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IF103_RS03375	COG2914	Belongs to the UPF0125 (RnfH) family
IF103_RS03380	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IF103_RS03385	COG0735	belongs to the Fur family
IF103_RS03390	COG0497	DNA recombination
IF103_RS03395	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IF103_RS03400	COG0443	Heat shock 70 kDa protein
IF103_RS03405	COG0484	heat shock protein binding
IF103_RS03410	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IF103_RS03415	COG0505	Belongs to the CarA family
IF103_RS03420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IF103_RS03425	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IF103_RS03440	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IF103_RS03450	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IF103_RS03455	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IF103_RS03460	COG0149	triose-phosphate isomerase activity
IF103_RS03465	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IF103_RS03480	COG0779	Required for maturation of 30S ribosomal subunits
IF103_RS03485	COG0195	Participates in both transcription termination and antitermination
IF103_RS03490	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IF103_RS03495	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IF103_RS03500	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IF103_RS03505	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IF103_RS03510	COG1185	polyribonucleotide nucleotidyltransferase activity
IF103_RS03515	COG2823	Periplasmic or secreted lipoprotein
IF103_RS03540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IF103_RS03545	COG0166	Belongs to the GPI family
IF103_RS03550	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IF103_RS03555	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IF103_RS03565	COG0617	tRNA 3'-terminal CCA addition
IF103_RS03570	COG2204	response regulator
IF103_RS03575	COG4191	Histidine kinase
IF103_RS03585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IF103_RS03595	COG0436	Aminotransferase
IF103_RS03600	COG1489	DNA binding
IF103_RS03610	COG4558	Periplasmic binding protein
IF103_RS03615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IF103_RS03620	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IF103_RS03645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IF103_RS03655	COG3098	single-species biofilm formation
IF103_RS03660	COG0028	Belongs to the TPP enzyme family
IF103_RS03670	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IF103_RS03675	COG1183	phosphatidylcholine synthase activity
IF103_RS03680	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IF103_RS03685	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
IF103_RS03715	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IF103_RS03720	COG1074	ATP-dependent DNA helicase activity
IF103_RS03725	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IF103_RS03735	COG2199	diguanylate cyclase activity
IF103_RS03740	COG3047	cAMP biosynthetic process
IF103_RS03740	COG2885	chlorophyll binding
IF103_RS03765	COG4589	Belongs to the CDS family
IF103_RS03780	COG2453	phosphatase
IF103_RS03780	COG0671	phosphoesterase, PA-phosphatase related
IF103_RS03785	COG2267	carboxylic ester hydrolase activity
IF103_RS03790	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IF103_RS03795	COG0583	DNA-binding transcription factor activity
IF103_RS03815	COG2249	NAD(P)H dehydrogenase (quinone) activity
IF103_RS03820	COG0583	DNA-binding transcription factor activity
IF103_RS03830	COG0840	transmembrane signaling receptor activity
IF103_RS03835	COG2321	neutral zinc metallopeptidase
IF103_RS03840	COG3485	protocatechuate 3,4-dioxygenase
IF103_RS03845	COG3485	protocatechuate 3,4-dioxygenase
IF103_RS03850	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IF103_RS03855	COG2252	PERMEase
IF103_RS03865	COG1271	oxidase subunit
IF103_RS03870	COG1294	oxidase, subunit
IF103_RS03880	COG2813	Specifically methylates the guanine in position
IF103_RS03885	COG2197	response regulator
IF103_RS03895	COG1970	mechanosensitive ion channel activity
IF103_RS03905	COG2233	PERMEase
IF103_RS03915	COG1966	Carbon starvation protein
IF103_RS03920	COG2879	small protein
IF103_RS03925	COG0523	cobalamin synthesis protein
IF103_RS03935	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IF103_RS03945	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IF103_RS03985	COG1366	Belongs to the anti-sigma-factor antagonist family
IF103_RS03995	COG0583	DNA-binding transcription factor activity
IF103_RS04000	COG1380	Effector of murein hydrolase LrgA
IF103_RS04005	COG1346	cytolysis
IF103_RS04015	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS04025	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IF103_RS04090	COG2207	Transcriptional regulator
IF103_RS04090	COG3708	Transcriptional regulator
IF103_RS04095	COG0697	spore germination
IF103_RS04100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IF103_RS04105	COG0583	DNA-binding transcription factor activity
IF103_RS04125	COG1566	PFAM secretion protein HlyD family protein
IF103_RS04155	COG0300	oxidoreductase activity
IF103_RS04170	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IF103_RS04170	COG0662	Cupin 2, conserved barrel domain protein
IF103_RS04185	COG1696	Membrane protein involved in D-alanine export
IF103_RS04200	COG3420	alginic acid biosynthetic process
IF103_RS04210	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IF103_RS04215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IF103_RS04220	COG1215	transferase activity, transferring glycosyl groups
IF103_RS04225	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IF103_RS04240	COG1136	(ABC) transporter
IF103_RS04245	COG1136	(ABC) transporter
IF103_RS04245	COG0577	efflux transmembrane transporter activity
IF103_RS04260	COG3022	response to hydroperoxide
IF103_RS04270	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IF103_RS04275	COG0315	cyclic pyranopterin monophosphate synthase activity
IF103_RS04280	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IF103_RS04290	COG0513	Belongs to the DEAD box helicase family
IF103_RS04295	COG0400	carboxylic ester hydrolase activity
IF103_RS04300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IF103_RS04305	COG4597	amino acid ABC transporter
IF103_RS04310	COG0765	amino acid transport
IF103_RS04315	COG1126	abc transporter atp-binding protein
IF103_RS04320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IF103_RS04330	COG0175	sulfate reduction
IF103_RS04340	COG1522	sequence-specific DNA binding
IF103_RS04365	COG0180	Tryptophanyl-tRNA synthetase
IF103_RS04370	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IF103_RS04380	COG0667	Aldo Keto reductase
IF103_RS04385	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IF103_RS04390	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IF103_RS04395	COG0723	plastoquinol--plastocyanin reductase activity
IF103_RS04400	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IF103_RS04405	COG2857	Cytochrome c1
IF103_RS04410	COG0625	glutathione transferase activity
IF103_RS04415	COG2969	positive regulation of protein catabolic process
IF103_RS04425	COG2823	Periplasmic or secreted lipoprotein
IF103_RS04430	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IF103_RS04435	COG0792	nuclease activity
IF103_RS04440	COG3107	peptidoglycan biosynthetic process
IF103_RS04455	COG2001	Belongs to the MraZ family
IF103_RS04460	COG0275	rRNA processing
IF103_RS04475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IF103_RS04480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IF103_RS04485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IF103_RS04490	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IF103_RS04495	COG0772	Belongs to the SEDS family
IF103_RS04500	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IF103_RS04505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IF103_RS04510	COG1181	Belongs to the D-alanine--D-alanine ligase family
IF103_RS04525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IF103_RS04530	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IF103_RS04540	COG0653	protein targeting
IF103_RS04545	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IF103_RS04555	COG0494	nUDIX hydrolase
IF103_RS04560	COG2096	Adenosyltransferase
IF103_RS04565	COG4191	Histidine kinase
IF103_RS04565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IF103_RS04575	COG1666	GTP binding
IF103_RS04580	COG0668	transmembrane transport
IF103_RS04610	COG3030	protein affecting phage T7 exclusion by the F plasmid
IF103_RS04615	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IF103_RS04620	COG0459	protein refolding
IF103_RS04635	COG0642	Histidine kinase
IF103_RS04645	COG3642	lipopolysaccharide core region biosynthetic process
IF103_RS04670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IF103_RS04675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IF103_RS04705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IF103_RS04715	COG0583	DNA-binding transcription factor activity
IF103_RS04720	COG0702	epimerase
IF103_RS04730	COG1902	pentaerythritol trinitrate reductase activity
IF103_RS04780	COG0693	protein deglycase activity
IF103_RS04795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IF103_RS04795	COG3153	acetyltransferase
IF103_RS04825	COG2925	Exonuclease
IF103_RS04835	COG0788	formyltetrahydrofolate deformylase activity
IF103_RS04855	COG0840	transmembrane signaling receptor activity
IF103_RS04860	COG0433	COG0433 Predicted ATPase
IF103_RS04865	COG0306	phosphate transporter
IF103_RS04875	COG1414	Transcriptional regulator
IF103_RS04880	COG2814	Major facilitator Superfamily
IF103_RS04885	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IF103_RS04890	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IF103_RS04895	COG0183	Belongs to the thiolase family
IF103_RS04900	COG0477	Major facilitator Superfamily
IF103_RS04905	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IF103_RS04910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IF103_RS04915	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IF103_RS04945	COG1309	transcriptional regulator
IF103_RS04950	COG0477	Major facilitator Superfamily
IF103_RS04955	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IF103_RS04965	COG2910	NAD(P)H-binding
IF103_RS04970	COG0583	DNA-binding transcription factor activity
IF103_RS04980	COG2207	Transcriptional regulator
IF103_RS05010	COG0477	Major facilitator Superfamily
IF103_RS05020	COG4191	Histidine kinase
IF103_RS05080	COG1024	Enoyl-CoA hydratase
IF103_RS05085	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IF103_RS05090	COG3180	Ammonia monooxygenase
IF103_RS05130	COG0354	folic acid binding
IF103_RS05135	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IF103_RS05165	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IF103_RS05170	COG0481	GTPase activity
IF103_RS05175	COG0681	Belongs to the peptidase S26 family
IF103_RS05180	COG0571	ribonuclease III activity
IF103_RS05185	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IF103_RS05190	COG1381	Involved in DNA repair and RecF pathway recombination
IF103_RS05195	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IF103_RS05215	COG0500	methyltransferase
IF103_RS05220	COG2226	methyltransferase
IF103_RS05230	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IF103_RS05245	COG4206	TonB-dependent receptor
IF103_RS05250	COG4628	conserved protein (DUF2132)
IF103_RS05260	COG2375	cellular response to nickel ion
IF103_RS05265	COG1695	Transcriptional regulator
IF103_RS05275	COG1113	amino acid transport
IF103_RS05305	COG1201	RNA secondary structure unwinding
IF103_RS05310	COG0494	nUDIX hydrolase
IF103_RS05315	COG0583	DNA-binding transcription factor activity
IF103_RS05340	COG1126	abc transporter atp-binding protein
IF103_RS05345	COG0765	amino acid transport
IF103_RS05350	COG0765	amino acid transport
IF103_RS05355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IF103_RS05375	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IF103_RS05385	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IF103_RS05390	COG3842	ATPase activity
IF103_RS05395	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IF103_RS05400	COG0243	molybdopterin cofactor binding
IF103_RS05405	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IF103_RS05420	COG0450	alkyl hydroperoxide reductase
IF103_RS05425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IF103_RS05430	COG0418	dihydroorotase activity
IF103_RS05440	COG0137	argininosuccinate synthase activity
IF103_RS05450	COG2197	response regulator
IF103_RS05460	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IF103_RS05470	COG4659	FMN binding
IF103_RS05480	COG2878	Part of a membrane complex involved in electron transport
IF103_RS05485	COG4657	Part of a membrane complex involved in electron transport
IF103_RS05490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IF103_RS05490	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IF103_RS05495	COG0489	protein tyrosine kinase activity
IF103_RS05500	COG1278	Cold shock
IF103_RS05505	COG0717	Belongs to the dCTP deaminase family
IF103_RS05520	COG2366	antibiotic biosynthetic process
IF103_RS05525	COG0653	protein targeting
IF103_RS05535	COG3012	SEC-C Motif Domain Protein
IF103_RS05570	COG1199	ATP-dependent helicase activity
IF103_RS05590	COG0259	pyridoxamine-phosphate oxidase activity
IF103_RS05605	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
IF103_RS05650	COG2084	Dehydrogenase
IF103_RS05660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IF103_RS05695	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS05700	COG0583	DNA-binding transcription factor activity
IF103_RS05710	COG5001	Diguanylate cyclase
IF103_RS05720	COG2116	formate transmembrane transporter activity
IF103_RS05755	COG3318	Belongs to the UPF0149 family
IF103_RS05755	COG3012	SEC-C Motif Domain Protein
IF103_RS05760	COG0625	glutathione transferase activity
IF103_RS05765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IF103_RS05765	COG1017	nitric oxide dioxygenase activity
IF103_RS05805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IF103_RS05815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IF103_RS05820	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IF103_RS05820	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IF103_RS05830	COG2205	protein histidine kinase activity
IF103_RS05870	COG1301	dicarboxylic acid transport
IF103_RS05880	COG3091	SprT-like family
IF103_RS05890	COG0037	tRNA processing
IF103_RS05910	COG1393	Belongs to the ArsC family
IF103_RS05930	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IF103_RS05935	COG0784	Response regulator, receiver
IF103_RS05935	COG5002	protein histidine kinase activity
IF103_RS05935	COG2205	protein histidine kinase activity
IF103_RS05955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IF103_RS05960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IF103_RS05965	COG3956	TIGRFAM MazG family protein
IF103_RS05970	COG3122	Protein conserved in bacteria
IF103_RS05985	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IF103_RS05990	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IF103_RS06000	COG0628	permease
IF103_RS06010	COG0791	NLP P60 protein
IF103_RS06015	COG0791	NLP P60 protein
IF103_RS06025	COG1797	cobyrinic acid a,c-diamide synthase activity
IF103_RS06030	COG0778	Nitroreductase
IF103_RS06035	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
IF103_RS06045	COG1492	cobalamin metabolic process
IF103_RS06055	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IF103_RS06060	COG0406	alpha-ribazole phosphatase activity
IF103_RS06065	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IF103_RS06070	COG1846	Transcriptional regulator
IF103_RS06120	COG2205	protein histidine kinase activity
IF103_RS06125	COG2814	Major facilitator Superfamily
IF103_RS06130	COG2188	Transcriptional regulator
IF103_RS06135	COG2814	Major facilitator Superfamily
IF103_RS06140	COG3618	amidohydrolase
IF103_RS06145	COG0840	transmembrane signaling receptor activity
IF103_RS06150	COG0477	Major facilitator Superfamily
IF103_RS06155	COG2076	Multidrug Resistance protein
IF103_RS06160	COG0385	Bile acid
IF103_RS06165	COG2974	May be involved in recombination
IF103_RS06180	COG0024	Methionine aminopeptidase
IF103_RS06185	COG0243	molybdopterin cofactor binding
IF103_RS06190	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IF103_RS06190	COG2146	nitrite reductase [NAD(P)H] activity
IF103_RS06195	COG2146	nitrite reductase [NAD(P)H] activity
IF103_RS06195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IF103_RS06200	COG0583	DNA-binding transcription factor activity
IF103_RS06210	COG3339	Conserved Protein
IF103_RS06225	COG2200	EAL domain
IF103_RS06230	COG0793	Belongs to the peptidase S41A family
IF103_RS06255	COG0395	ABC-type sugar transport system, permease component
IF103_RS06260	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IF103_RS06275	COG0668	transmembrane transport
IF103_RS06285	COG1362	aminopeptidase activity
IF103_RS06290	COG0564	pseudouridine synthase activity
IF103_RS06295	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IF103_RS06300	COG2894	cell division
IF103_RS06305	COG0850	regulation of cytokinetic process
IF103_RS06310	COG1560	Kdo2-lipid A biosynthetic process
IF103_RS06320	COG2853	Lipoprotein
IF103_RS06340	COG2113	Glycine betaine
IF103_RS06345	COG3162	membrane
IF103_RS06350	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IF103_RS06370	COG3089	Belongs to the UPF0270 family
IF103_RS06375	COG1363	Peptidase, m42
IF103_RS06380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IF103_RS06380	COG0189	ligase activity
IF103_RS06385	COG0367	asparagine synthase
IF103_RS06390	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IF103_RS06390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IF103_RS06395	COG2326	polyphosphate kinase activity
IF103_RS06400	COG0697	spore germination
IF103_RS06405	COG0114	fumarate hydratase activity
IF103_RS06415	COG0271	Belongs to the BolA IbaG family
IF103_RS06420	COG1054	Belongs to the UPF0176 family
IF103_RS06435	COG5001	Diguanylate cyclase
IF103_RS06435	COG5002	protein histidine kinase activity
IF103_RS06445	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS06450	COG0546	phosphoglycolate phosphatase activity
IF103_RS06455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IF103_RS06460	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IF103_RS06470	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IF103_RS06480	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IF103_RS06485	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IF103_RS06500	COG0776	regulation of translation
IF103_RS06510	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IF103_RS06525	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IF103_RS06555	COG1215	transferase activity, transferring glycosyl groups
IF103_RS06560	COG1045	serine acetyltransferase
IF103_RS06570	COG0367	asparagine synthase
IF103_RS06575	COG0438	transferase activity, transferring glycosyl groups
IF103_RS06580	COG0438	transferase activity, transferring glycosyl groups
IF103_RS06590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IF103_RS06605	COG1091	dTDP-4-dehydrorhamnose reductase activity
IF103_RS06620	COG1555	photosystem II stabilization
IF103_RS06635	COG0284	orotidine-5'-phosphate decarboxylase activity
IF103_RS06645	COG1215	transferase activity, transferring glycosyl groups
IF103_RS06660	COG2130	NADP-dependent
IF103_RS06665	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS06675	COG0436	Aminotransferase
IF103_RS06680	COG0840	transmembrane signaling receptor activity
IF103_RS06685	COG3135	benzoate transporter
IF103_RS06690	COG0625	glutathione transferase activity
IF103_RS06700	COG0302	gtp cyclohydrolase
IF103_RS06735	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IF103_RS06740	COG2814	Major facilitator Superfamily
IF103_RS06745	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IF103_RS06770	COG1368	sulfuric ester hydrolase activity
IF103_RS06790	COG0519	Catalyzes the synthesis of GMP from XMP
IF103_RS06795	COG0598	Magnesium transport protein CorA
IF103_RS06800	COG0204	Acyl-transferase
IF103_RS06820	COG2814	Major facilitator Superfamily
IF103_RS06825	COG0583	DNA-binding transcription factor activity
IF103_RS06830	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS06835	COG0583	DNA-binding transcription factor activity
IF103_RS06855	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IF103_RS06860	COG1764	response to oxidative stress
IF103_RS06865	COG1846	Transcriptional regulator
IF103_RS06870	COG0583	DNA-binding transcription factor activity
IF103_RS06880	COG0583	DNA-binding transcription factor activity
IF103_RS06890	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
IF103_RS06905	COG3384	dioxygenase
IF103_RS06910	COG0500	methyltransferase
IF103_RS06915	COG0501	Belongs to the peptidase M48B family
IF103_RS06920	COG0436	Aminotransferase
IF103_RS06925	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IF103_RS06930	COG0386	Belongs to the glutathione peroxidase family
IF103_RS06945	COG1956	GAF domain-containing protein
IF103_RS06985	COG3188	usher protein
IF103_RS07020	COG3468	outer membrane autotransporter barrel domain protein
IF103_RS07050	COG1960	acyl-CoA dehydrogenase activity
IF103_RS07055	COG0625	glutathione transferase activity
IF103_RS07060	COG1131	(ABC) transporter
IF103_RS07065	COG0842	Transport permease protein
IF103_RS07080	COG0811	peptide transport
IF103_RS07085	COG0848	biopolymer transport protein
IF103_RS07090	COG1663	tetraacyldisaccharide 4'-kinase activity
IF103_RS07095	COG2835	tetraacyldisaccharide 4'-kinase activity
IF103_RS07100	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IF103_RS07105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IF103_RS07110	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IF103_RS07115	COG1530	ribonuclease E activity
IF103_RS07125	COG0546	phosphoglycolate phosphatase activity
IF103_RS07130	COG0616	signal peptide processing
IF103_RS07130	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IF103_RS07135	COG0424	maF-like protein
IF103_RS07145	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IF103_RS07150	COG0416	fatty acid biosynthetic process
IF103_RS07165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IF103_RS07170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IF103_RS07180	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IF103_RS07185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IF103_RS07195	COG0084	hydrolase, TatD family'
IF103_RS07210	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IF103_RS07240	COG0556	nucleotide-excision repair
IF103_RS07255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IF103_RS07305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IF103_RS07325	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IF103_RS07330	COG0066	3-isopropylmalate dehydratase activity
IF103_RS07335	COG2226	methyltransferase
IF103_RS07340	COG0473	3-isopropylmalate dehydrogenase activity
IF103_RS07365	COG0135	phosphoribosylanthranilate isomerase activity
IF103_RS07370	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IF103_RS07375	COG0285	dihydrofolate synthase activity
IF103_RS07385	COG1286	toxin biosynthetic process
IF103_RS07440	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IF103_RS07445	COG3188	usher protein
IF103_RS07450	COG3121	Chaperone
IF103_RS07460	COG2197	response regulator
IF103_RS07470	COG2199	diguanylate cyclase activity
IF103_RS07470	COG2200	EAL domain
IF103_RS07470	COG2202	Pas domain
IF103_RS07495	COG0446	pyridine nucleotide-disulphide oxidoreductase
IF103_RS07495	COG1902	pentaerythritol trinitrate reductase activity
IF103_RS07505	COG3038	cytochrome b561
IF103_RS07520	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IF103_RS07525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IF103_RS07530	COG0705	Rhomboid family
IF103_RS07545	COG0308	aminopeptidase N
IF103_RS07565	COG2706	6-phosphogluconolactonase activity
IF103_RS07585	COG0420	3'-5' exonuclease activity
IF103_RS07615	COG0714	Associated with various cellular activities
IF103_RS07635	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IF103_RS07650	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IF103_RS07665	COG0668	transmembrane transport
IF103_RS07685	COG2815	serine threonine protein kinase
IF103_RS07685	COG0515	serine threonine protein kinase
IF103_RS07690	COG2223	nitrite transmembrane transporter activity
IF103_RS07695	COG3707	response regulator
IF103_RS07700	COG1116	anion transmembrane transporter activity
IF103_RS07700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IF103_RS07705	COG0167	dihydroorotate dehydrogenase activity
IF103_RS07710	COG3130	regulation of translation
IF103_RS07715	COG0116	Belongs to the methyltransferase superfamily
IF103_RS07715	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IF103_RS07725	COG2027	D-alanyl-D-alanine carboxypeptidase
IF103_RS07730	COG3171	Protein conserved in bacteria
IF103_RS07735	COG2205	protein histidine kinase activity
IF103_RS07735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IF103_RS07740	COG2197	response regulator
IF103_RS07765	COG0004	ammonium transporteR
IF103_RS07785	COG0840	transmembrane signaling receptor activity
IF103_RS07795	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
IF103_RS07800	COG0425	Belongs to the sulfur carrier protein TusA family
IF103_RS07805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IF103_RS07815	COG1132	(ABC) transporter
IF103_RS07840	COG0521	Mo-molybdopterin cofactor biosynthetic process
IF103_RS07860	COG1597	lipid kinase activity
IF103_RS07865	COG2197	response regulator
IF103_RS07870	COG3851	Histidine kinase
IF103_RS07880	COG0835	chemotaxis
IF103_RS07880	COG0784	Response regulator, receiver
IF103_RS07890	COG0741	lytic transglycosylase activity
IF103_RS07895	COG0488	(ABC) transporter
IF103_RS07900	COG0589	response to stress
IF103_RS07910	COG1250	3-hydroxyacyl-CoA dehydrogenase
IF103_RS07910	COG1024	Enoyl-CoA hydratase
IF103_RS07915	COG0183	Belongs to the thiolase family
IF103_RS07945	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IF103_RS07965	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IF103_RS07975	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IF103_RS07985	COG1477	protein flavinylation
IF103_RS07990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IF103_RS07995	COG0584	glycerophosphoryl diester phosphodiesterase
IF103_RS08005	COG4591	ABC-type transport system involved in lipoprotein release permease component
IF103_RS08010	COG1136	(ABC) transporter
IF103_RS08015	COG4591	ABC-type transport system involved in lipoprotein release permease component
IF103_RS08030	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IF103_RS08030	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IF103_RS08045	COG2853	Lipoprotein
IF103_RS08055	COG4566	intracellular signal transduction
IF103_RS08070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IF103_RS08075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IF103_RS08090	COG2814	Major facilitator Superfamily
IF103_RS08120	COG3383	formate dehydrogenase (NAD+) activity
IF103_RS08170	COG0730	response to heat
IF103_RS08175	COG0840	transmembrane signaling receptor activity
IF103_RS08180	COG0583	DNA-binding transcription factor activity
IF103_RS08200	COG2186	Transcriptional regulator
IF103_RS08215	COG0840	transmembrane signaling receptor activity
IF103_RS08230	COG2423	ornithine cyclodeaminase activity
IF103_RS08240	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IF103_RS08275	COG0544	peptidyl-prolyl cis-trans isomerase activity
IF103_RS08280	COG0740	serine-type endopeptidase activity
IF103_RS08285	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IF103_RS08290	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IF103_RS08300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IF103_RS08340	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IF103_RS08345	COG2259	Doxx family
IF103_RS08355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IF103_RS08360	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IF103_RS08365	COG4181	ATPase activity
IF103_RS08400	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IF103_RS08405	COG0589	response to stress
IF103_RS08435	COG0189	ligase activity
IF103_RS08435	COG4067	protein conserved in archaea
IF103_RS08440	COG1802	Transcriptional regulator
IF103_RS08450	COG0372	Belongs to the citrate synthase family
IF103_RS08465	COG2079	MmgE PrpD family protein
IF103_RS08480	COG0720	synthase
IF103_RS08510	COG0517	IMP dehydrogenase activity
IF103_RS08510	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IF103_RS08510	COG0617	tRNA 3'-terminal CCA addition
IF103_RS08525	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IF103_RS08545	COG0745	RESPONSE REGULATOR receiver
IF103_RS08550	COG4251	negative regulation of phosphorylation
IF103_RS08590	COG2866	Carboxypeptidase
IF103_RS08635	COG0174	glutamine synthetase
IF103_RS08640	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IF103_RS08655	COG4172	Belongs to the ABC transporter superfamily
IF103_RS08660	COG4239	(ABC) transporter, permease
IF103_RS08665	COG4174	ABC transporter (Permease)
IF103_RS08670	COG4166	transmembrane transport
IF103_RS08675	COG4166	transmembrane transport
IF103_RS08680	COG0741	lytic transglycosylase activity
IF103_RS08680	COG1388	LysM domain
IF103_RS08685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IF103_RS08695	COG0328	RNA-DNA hybrid ribonuclease activity
IF103_RS08700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IF103_RS08715	COG0431	NADPH-dependent FMN reductase
IF103_RS08720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IF103_RS08725	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IF103_RS08730	COG0583	DNA-binding transcription factor activity
IF103_RS08750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IF103_RS08760	COG0183	Belongs to the thiolase family
IF103_RS08765	COG1960	acyl-CoA dehydrogenase activity
IF103_RS08770	COG1024	Enoyl-CoA hydratase
IF103_RS08795	COG1320	monovalent cation:proton antiporter activity
IF103_RS08800	COG2212	antiporter activity
IF103_RS08810	COG0651	ATP synthesis coupled electron transport
IF103_RS08815	COG1006	Multisubunit Na H antiporter MnhC subunit
IF103_RS08820	COG2111	Na H antiporter
IF103_RS08820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IF103_RS08835	COG1335	isochorismatase
IF103_RS08905	COG0589	response to stress
IF103_RS08945	COG0583	DNA-binding transcription factor activity
IF103_RS08955	COG0010	Belongs to the arginase family
IF103_RS08965	COG2133	pyrroloquinoline quinone binding
IF103_RS08985	COG1278	Cold shock
IF103_RS08995	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IF103_RS09000	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IF103_RS09005	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IF103_RS09010	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IF103_RS09015	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IF103_RS09020	COG0072	phenylalanine-tRNA ligase activity
IF103_RS09025	COG0776	regulation of translation
IF103_RS09055	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IF103_RS09060	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IF103_RS09070	COG1301	dicarboxylic acid transport
IF103_RS09075	COG0583	DNA-binding transcription factor activity
IF103_RS09125	COG2207	Transcriptional regulator
IF103_RS09145	COG4221	oxidoreductase activity
IF103_RS09200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IF103_RS09245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IF103_RS09250	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
IF103_RS09280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IF103_RS09285	COG1960	acyl-CoA dehydrogenase activity
IF103_RS09290	COG0318	PFAM AMP-dependent synthetase and ligase
IF103_RS09305	COG0366	Alpha amylase catalytic
IF103_RS09310	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IF103_RS09355	COG2204	response regulator
IF103_RS09430	COG1640	4-alpha-glucanotransferase
IF103_RS09435	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IF103_RS09440	COG0297	glycogen (starch) synthase activity
IF103_RS09450	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IF103_RS09455	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IF103_RS09460	COG1309	transcriptional regulator
IF103_RS09470	COG0493	'glutamate synthase
IF103_RS09480	COG1953	Uracil, thiamine, allantoin
IF103_RS09490	COG1234	tRNA 3'-trailer cleavage
IF103_RS09495	COG3040	lipid binding
IF103_RS09500	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IF103_RS09505	COG1024	Enoyl-CoA hydratase
IF103_RS09510	COG2816	NAD+ diphosphatase activity
IF103_RS09515	COG0730	response to heat
IF103_RS09520	COG1104	cysteine desulfurase activity
IF103_RS09535	COG1418	mRNA catabolic process
IF103_RS09540	COG0861	Integral membrane protein TerC family
IF103_RS09545	COG1414	Transcriptional regulator
IF103_RS09550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IF103_RS09555	COG0765	amino acid transport
IF103_RS09560	COG1126	abc transporter atp-binding protein
IF103_RS09565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IF103_RS09575	COG3842	ATPase activity
IF103_RS09580	COG1177	transmembrane transport
IF103_RS09585	COG1176	ABC-type spermidine putrescine transport system, permease component I
IF103_RS09595	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IF103_RS09605	COG1741	Belongs to the pirin family
IF103_RS09620	COG0583	DNA-binding transcription factor activity
IF103_RS09625	COG0583	DNA-binding transcription factor activity
IF103_RS09630	COG0477	Major facilitator Superfamily
IF103_RS09645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IF103_RS09655	COG4106	trans-aconitate 2-methyltransferase activity
IF103_RS09670	COG0625	glutathione transferase activity
IF103_RS09680	COG0393	Putative heavy-metal-binding
IF103_RS09725	COG4221	oxidoreductase activity
IF103_RS09740	COG1917	Cupin 2, conserved barrel domain protein
IF103_RS09740	COG1396	sequence-specific DNA binding
IF103_RS09745	COG0477	Major facilitator Superfamily
IF103_RS09750	COG3038	cytochrome b561
IF103_RS09755	COG0753	catalase activity
IF103_RS09770	COG0708	Exodeoxyribonuclease III
IF103_RS09780	COG0729	surface antigen
IF103_RS09795	COG1902	pentaerythritol trinitrate reductase activity
IF103_RS09805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IF103_RS09805	COG2010	Cytochrome c
IF103_RS09810	COG2080	2 iron, 2 sulfur cluster binding
IF103_RS09815	COG2010	Cytochrome c
IF103_RS09815	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IF103_RS09820	COG2814	Major facilitator Superfamily
IF103_RS09825	COG0583	DNA-binding transcription factor activity
IF103_RS09855	COG2366	antibiotic biosynthetic process
IF103_RS09860	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IF103_RS09870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IF103_RS09875	COG0215	cysteine-tRNA ligase activity
IF103_RS09885	COG0745	RESPONSE REGULATOR receiver
IF103_RS09915	COG3675	Pfam Lipase (class 3)
IF103_RS09920	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IF103_RS09930	COG0583	DNA-binding transcription factor activity
IF103_RS09940	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IF103_RS09945	COG0583	DNA-binding transcription factor activity
IF103_RS09965	COG3180	Ammonia monooxygenase
IF103_RS09980	COG0768	penicillin binding
IF103_RS09985	COG0471	metal ion transport
IF103_RS09990	COG1064	alcohol dehydrogenase
IF103_RS09995	COG1012	belongs to the aldehyde dehydrogenase family
IF103_RS10000	COG1177	transmembrane transport
IF103_RS10005	COG1176	ABC-type spermidine putrescine transport system, permease component I
IF103_RS10010	COG3842	ATPase activity
IF103_RS10015	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IF103_RS10020	COG1012	belongs to the aldehyde dehydrogenase family
IF103_RS10025	COG0583	DNA-binding transcription factor activity
IF103_RS10030	COG0583	DNA-binding transcription factor activity
IF103_RS10035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IF103_RS10040	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IF103_RS10075	COG1472	Belongs to the glycosyl hydrolase 3 family
IF103_RS10095	COG2814	Major facilitator Superfamily
IF103_RS10100	COG2814	Major facilitator Superfamily
IF103_RS10120	COG0673	inositol 2-dehydrogenase activity
IF103_RS10155	COG1473	amidohydrolase
IF103_RS10160	COG0039	L-malate dehydrogenase activity
IF103_RS10185	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IF103_RS10190	COG0765	amino acid transport
IF103_RS10195	COG0765	amino acid transport
IF103_RS10200	COG1126	abc transporter atp-binding protein
IF103_RS10245	COG1120	ATPase activity
IF103_RS10250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IF103_RS10265	COG0113	porphobilinogen synthase activity
IF103_RS10275	COG0307	riboflavin synthase, alpha
IF103_RS10285	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IF103_RS10295	COG1984	allophanate hydrolase subunit 2
IF103_RS10310	COG0583	DNA-binding transcription factor activity
IF103_RS10320	COG4106	trans-aconitate 2-methyltransferase activity
IF103_RS10330	COG0019	diaminopimelate decarboxylase activity
IF103_RS10340	COG0583	DNA-binding transcription factor activity
IF103_RS10345	COG2271	Major facilitator Superfamily
IF103_RS10350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IF103_RS10355	COG0217	transcriptional regulatory protein
IF103_RS10365	COG0076	glutamate decarboxylase activity
IF103_RS10370	COG0477	Major facilitator Superfamily
IF103_RS10375	COG1082	Xylose isomerase domain protein TIM barrel
IF103_RS10375	COG3185	4-Hydroxyphenylpyruvate dioxygenase
IF103_RS10380	COG1309	transcriptional regulator
IF103_RS10405	COG5001	Diguanylate cyclase
IF103_RS10410	COG0656	L-ascorbic acid biosynthetic process
IF103_RS10430	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
IF103_RS10445	COG0477	Major facilitator Superfamily
IF103_RS10455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IF103_RS10460	COG3706	GGDEF domain
IF103_RS10465	COG1611	Belongs to the LOG family
IF103_RS10470	COG2855	membrane
IF103_RS10495	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IF103_RS10500	COG2218	PFAM glutamate synthase alpha subunit domain protein
IF103_RS10505	COG0069	glutamate synthase activity
IF103_RS10525	COG2186	Transcriptional regulator
IF103_RS10530	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IF103_RS10540	COG1012	belongs to the aldehyde dehydrogenase family
IF103_RS10545	COG2267	carboxylic ester hydrolase activity
IF103_RS10555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IF103_RS10560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IF103_RS10565	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IF103_RS10570	COG1960	acyl-CoA dehydrogenase activity
IF103_RS10620	COG3209	COG3209 Rhs family protein
IF103_RS10685	COG3052	prosthetic group binding
IF103_RS10705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IF103_RS10725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IF103_RS10730	COG0235	Class ii aldolase
IF103_RS10740	COG0583	DNA-binding transcription factor activity
IF103_RS10750	COG1280	lysine exporter protein (LysE YggA)
IF103_RS10780	COG0583	DNA-binding transcription factor activity
IF103_RS10785	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS10820	COG1944	ATP diphosphatase activity
IF103_RS10850	COG2391	methyltransferase activity
IF103_RS10865	COG2186	Transcriptional regulator
IF103_RS10870	COG1012	belongs to the aldehyde dehydrogenase family
IF103_RS10875	COG2721	sulfolactate sulfo-lyase activity
IF103_RS10880	COG2271	Major facilitator Superfamily
IF103_RS10885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IF103_RS10890	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IF103_RS10895	COG1126	abc transporter atp-binding protein
IF103_RS10900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IF103_RS10930	COG1448	Aminotransferase
IF103_RS10940	COG0814	amino acid
IF103_RS10965	COG1538	Outer membrane efflux protein
IF103_RS10990	COG4974	Belongs to the 'phage' integrase family
IF103_RS10995	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS11000	COG0784	Response regulator, receiver
IF103_RS11000	COG4191	Histidine kinase
IF103_RS11005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IF103_RS11010	COG0348	domain, Protein
IF103_RS11015	COG1285	pathogenesis
IF103_RS11025	COG0789	Transcriptional regulator
IF103_RS11030	COG2207	Transcriptional regulator
IF103_RS11040	COG0829	nickel cation binding
IF103_RS11045	COG0831	urea catabolic process
IF103_RS11050	COG0832	Belongs to the urease beta subunit family
IF103_RS11055	COG0804	urea catabolic process
IF103_RS11060	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
IF103_RS11070	COG0830	nickel cation binding
IF103_RS11075	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IF103_RS11090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IF103_RS11095	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IF103_RS11110	COG0587	DNA-directed DNA polymerase activity
IF103_RS11115	COG0656	L-ascorbic acid biosynthetic process
IF103_RS11125	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IF103_RS11135	COG2031	fatty acid transporter
IF103_RS11145	COG2207	Transcriptional regulator
IF103_RS11185	COG3209	COG3209 Rhs family protein
IF103_RS11195	COG1476	TRANSCRIPTIONal
IF103_RS11225	COG1253	flavin adenine dinucleotide binding
IF103_RS11235	COG2200	EAL domain
IF103_RS11255	COG0784	Response regulator, receiver
IF103_RS11255	COG4191	Histidine kinase
IF103_RS11260	COG4191	Histidine kinase
IF103_RS11260	COG0784	Response regulator, receiver
IF103_RS11280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IF103_RS11300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IF103_RS11305	COG0826	peptidase U32
IF103_RS11315	COG2384	SAM-dependent methyltransferase
IF103_RS11350	COG1473	amidohydrolase
IF103_RS11360	COG0154	amidase activity
IF103_RS11375	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS11380	COG1053	succinate dehydrogenase
IF103_RS11390	COG2814	Major facilitator Superfamily
IF103_RS11400	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IF103_RS11405	COG0745	RESPONSE REGULATOR receiver
IF103_RS11410	COG2205	protein histidine kinase activity
IF103_RS11430	COG4603	Belongs to the binding-protein-dependent transport system permease family
IF103_RS11435	COG3845	ABC transporter
IF103_RS11445	COG3706	GGDEF domain
IF103_RS11460	COG1215	transferase activity, transferring glycosyl groups
IF103_RS11465	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IF103_RS11475	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IF103_RS11540	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IF103_RS11570	COG1045	serine acetyltransferase
IF103_RS11580	COG2990	Protein conserved in bacteria
IF103_RS11600	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IF103_RS11605	COG0583	DNA-binding transcription factor activity
IF103_RS11610	COG1760	l-serine dehydratase
IF103_RS11615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IF103_RS11625	COG0174	glutamine synthetase
IF103_RS11640	COG1012	belongs to the aldehyde dehydrogenase family
IF103_RS11645	COG0583	DNA-binding transcription factor activity
IF103_RS11720	COG2814	Major facilitator Superfamily
IF103_RS11725	COG4948	Mandelate Racemase Muconate Lactonizing
IF103_RS11730	COG4829	muconolactone delta-isomerase
IF103_RS11735	COG3485	protocatechuate 3,4-dioxygenase
IF103_RS11740	COG3135	benzoate transporter
IF103_RS11755	COG0667	Aldo Keto reductase
IF103_RS11760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IF103_RS11765	COG2271	Major facilitator Superfamily
IF103_RS11780	COG3835	regulator
IF103_RS11785	COG1929	Belongs to the glycerate kinase type-1 family
IF103_RS11815	COG0154	amidase activity
IF103_RS11820	COG0367	asparagine synthase
IF103_RS11825	COG0583	DNA-binding transcription factor activity
IF103_RS11830	COG3386	PFAM SMP-30 Gluconolaconase
IF103_RS11840	COG1999	signal sequence binding
IF103_RS11850	COG0004	ammonium transporteR
IF103_RS11860	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IF103_RS11865	COG0492	ferredoxin-NADP+ reductase activity
IF103_RS11870	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IF103_RS11880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IF103_RS11900	COG2197	response regulator
IF103_RS11905	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS11915	COG1942	4-Oxalocrotonate Tautomerase
IF103_RS11930	COG0583	DNA-binding transcription factor activity
IF103_RS11935	COG2814	Major facilitator Superfamily
IF103_RS11975	COG2837	iron assimilation
IF103_RS11995	COG2194	sulfuric ester hydrolase activity
IF103_RS12010	COG2030	dehydratase
IF103_RS12010	COG1012	belongs to the aldehyde dehydrogenase family
IF103_RS12025	COG3162	membrane
IF103_RS12030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IF103_RS12035	COG2151	metal-sulfur cluster biosynthetic enzyme
IF103_RS12040	COG3396	Phenylacetate-CoA oxygenase
IF103_RS12045	COG3460	Phenylacetate-CoA oxygenase
IF103_RS12050	COG3396	Phenylacetate-CoA oxygenase
IF103_RS12060	COG0183	Belongs to the thiolase family
IF103_RS12065	COG2050	protein possibly involved in aromatic compounds catabolism
IF103_RS12070	COG1250	3-hydroxyacyl-CoA dehydrogenase
IF103_RS12075	COG1024	Enoyl-CoA hydratase
IF103_RS12080	COG1024	Enoyl-CoA hydratase
IF103_RS12090	COG3327	negative regulation of DNA-templated transcription, initiation
IF103_RS12110	COG4977	sequence-specific DNA binding
IF103_RS12115	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS12120	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
IF103_RS12150	COG0183	Belongs to the thiolase family
IF103_RS12155	COG0824	Thioesterase
IF103_RS12160	COG1454	alcohol dehydrogenase
IF103_RS12165	COG1960	acyl-CoA dehydrogenase activity
IF103_RS12170	COG1250	3-hydroxyacyl-CoA dehydrogenase
IF103_RS12170	COG1024	Enoyl-CoA hydratase
IF103_RS12175	COG0583	DNA-binding transcription factor activity
IF103_RS12180	COG2015	COG2015, Alkyl sulfatase and related hydrolases
IF103_RS12210	COG1960	acyl-CoA dehydrogenase activity
IF103_RS12215	COG0318	PFAM AMP-dependent synthetase and ligase
IF103_RS12225	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IF103_RS12230	COG2814	Major facilitator Superfamily
IF103_RS12235	COG2356	endonuclease I
IF103_RS12255	COG2205	protein histidine kinase activity
IF103_RS12260	COG0745	RESPONSE REGULATOR receiver
IF103_RS12265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IF103_RS12275	COG0746	molybdenum cofactor guanylyltransferase activity
IF103_RS12280	COG0318	PFAM AMP-dependent synthetase and ligase
IF103_RS12325	COG1132	(ABC) transporter
IF103_RS12330	COG3284	Transcriptional regulator
IF103_RS12355	COG3145	DNA-N1-methyladenine dioxygenase activity
IF103_RS12380	COG2165	general secretion pathway protein
IF103_RS12385	COG2165	general secretion pathway protein
IF103_RS12390	COG4796	Type ii and iii secretion system protein
IF103_RS12415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IF103_RS12420	COG2204	response regulator
IF103_RS12475	COG2826	transposase and inactivated derivatives, IS30 family
IF103_RS12490	COG4104	PAAR repeat-containing protein
IF103_RS12490	COG3209	COG3209 Rhs family protein
IF103_RS12525	COG1414	Transcriptional regulator
IF103_RS12530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IF103_RS12535	COG1053	succinate dehydrogenase
IF103_RS12545	COG1053	succinate dehydrogenase
IF103_RS12550	COG2271	Major facilitator Superfamily
IF103_RS12570	COG1053	succinate dehydrogenase
IF103_RS12605	COG3008	intermembrane lipid transfer
IF103_RS12610	COG2995	paraquat-inducible protein a
IF103_RS12675	COG4106	trans-aconitate 2-methyltransferase activity
IF103_RS12685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IF103_RS12695	COG3257	ureidoglycine aminohydrolase activity
IF103_RS12720	COG1522	sequence-specific DNA binding
IF103_RS12740	COG1959	2 iron, 2 sulfur cluster binding
IF103_RS12755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IF103_RS12760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IF103_RS12765	COG4166	transmembrane transport
IF103_RS12770	COG4174	ABC transporter (Permease)
IF103_RS12775	COG4239	(ABC) transporter, permease
IF103_RS12780	COG3829	transcription factor binding
IF103_RS12780	COG3290	protein histidine kinase activity
IF103_RS12785	COG2610	gluconate transmembrane transporter activity
IF103_RS12790	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS12795	COG4574	serine-type endopeptidase inhibitor activity
IF103_RS12800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IF103_RS12805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IF103_RS12825	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IF103_RS12845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IF103_RS12855	COG2135	peptidase activity
IF103_RS12895	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IF103_RS12900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IF103_RS12905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IF103_RS12920	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IF103_RS12945	COG2200	EAL domain
IF103_RS12945	COG2199	diguanylate cyclase activity
IF103_RS12945	COG3287	FIST C domain
IF103_RS12950	COG3706	GGDEF domain
IF103_RS12960	COG1230	cation diffusion facilitator family transporter
IF103_RS12970	COG0488	(ABC) transporter
IF103_RS12985	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IF103_RS13005	COG1968	undecaprenyl-diphosphatase activity
IF103_RS13010	COG0840	transmembrane signaling receptor activity
IF103_RS13060	COG2204	response regulator
IF103_RS13110	COG3813	Protein conserved in bacteria
IF103_RS13115	COG2197	response regulator
IF103_RS13120	COG2205	protein histidine kinase activity
IF103_RS13120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IF103_RS13130	COG1609	Transcriptional regulator
IF103_RS13145	COG2204	response regulator
IF103_RS13150	COG5002	protein histidine kinase activity
IF103_RS13155	COG5002	protein histidine kinase activity
IF103_RS13160	COG0739	heme binding
IF103_RS13160	COG0741	lytic transglycosylase activity
IF103_RS13160	COG1196	nuclear chromosome segregation
IF103_RS13170	COG1459	type II secretion system
IF103_RS13175	COG2814	Major facilitator Superfamily
IF103_RS13180	COG1566	PFAM secretion protein HlyD family protein
IF103_RS13185	COG1846	Transcriptional regulator
IF103_RS13190	COG4566	intracellular signal transduction
IF103_RS13200	COG0318	PFAM AMP-dependent synthetase and ligase
IF103_RS13205	COG1960	acyl-CoA dehydrogenase activity
IF103_RS13215	COG2056	Na+-H+ antiporter family
IF103_RS13220	COG0840	transmembrane signaling receptor activity
IF103_RS13245	COG1280	lysine exporter protein (LysE YggA)
IF103_RS13250	COG0583	DNA-binding transcription factor activity
IF103_RS13270	COG0346	lactoylglutathione lyase activity
IF103_RS13290	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS13315	COG0477	Major facilitator Superfamily
IF103_RS13320	COG0346	lactoylglutathione lyase activity
IF103_RS13325	COG0596	Alpha beta hydrolase
IF103_RS13335	COG0210	DNA helicase
IF103_RS13350	COG1199	ATP-dependent helicase activity
IF103_RS13350	COG1199	ATP-dependent helicase activity
IF103_RS13370	COG3321	synthase
IF103_RS13370	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS13370	COG0604	alcohol dehydrogenase
IF103_RS13425	COG0583	DNA-binding transcription factor activity
IF103_RS13430	COG0288	reversible hydration of carbon dioxide
IF103_RS13435	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
IF103_RS13465	COG2851	Citrate transporter
IF103_RS13470	COG1301	dicarboxylic acid transport
IF103_RS13475	COG2828	Protein conserved in bacteria
IF103_RS13480	COG0583	DNA-binding transcription factor activity
IF103_RS13505	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IF103_RS13520	COG0708	Exodeoxyribonuclease III
IF103_RS13525	COG0583	DNA-binding transcription factor activity
IF103_RS13530	COG4221	oxidoreductase activity
IF103_RS13530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IF103_RS13530	COG0604	alcohol dehydrogenase
IF103_RS13530	COG3321	synthase
IF103_RS13545	COG0583	DNA-binding transcription factor activity
IF103_RS13560	COG4977	sequence-specific DNA binding
IF103_RS13580	COG3712	iron ion homeostasis
IF103_RS13590	COG2249	NAD(P)H dehydrogenase (quinone) activity
IF103_RS13625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IF103_RS13640	COG2351	hydroxyisourate hydrolase activity
IF103_RS13650	COG2233	PERMEase
IF103_RS13655	COG0583	DNA-binding transcription factor activity
IF103_RS13675	COG0668	transmembrane transport
IF103_RS13680	COG0789	Transcriptional regulator
IF103_RS13685	COG2202	Pas domain
IF103_RS13685	COG1366	Belongs to the anti-sigma-factor antagonist family
IF103_RS13710	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IF103_RS13725	COG3046	protein related to deoxyribodipyrimidine photolyase
IF103_RS13740	COG0640	Transcriptional regulator
IF103_RS13745	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IF103_RS13780	COG0531	amino acid
IF103_RS13790	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IF103_RS13800	COG0589	response to stress
IF103_RS13810	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IF103_RS13815	COG0589	response to stress
IF103_RS13820	COG0459	protein refolding
IF103_RS13825	COG2217	Heavy metal translocating P-type atpase
IF103_RS13840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IF103_RS13850	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
IF103_RS13860	COG0071	Belongs to the small heat shock protein (HSP20) family
IF103_RS13910	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IF103_RS13935	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IF103_RS13945	COG0693	protein deglycase activity
IF103_RS13950	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
IF103_RS13955	COG2890	protein-(glutamine-N5) methyltransferase activity
IF103_RS13995	COG3568	Endonuclease Exonuclease Phosphatase
IF103_RS14000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IF103_RS14005	COG0392	lysyltransferase activity
IF103_RS14065	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS14075	COG1058	Belongs to the CinA family
IF103_RS14075	COG1546	Belongs to the CinA family
IF103_RS14095	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IF103_RS14100	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IF103_RS14120	COG4974	Belongs to the 'phage' integrase family
IF103_RS14140	COG0861	Integral membrane protein TerC family
IF103_RS14165	COG2259	Doxx family
IF103_RS14180	COG3220	belongs to the UPF0276 family
IF103_RS14200	COG0417	DNA replication proofreading
IF103_RS14205	COG0583	DNA-binding transcription factor activity
IF103_RS14245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IF103_RS14250	COG1982	Orn Lys Arg decarboxylase major
IF103_RS14265	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IF103_RS14280	COG1999	signal sequence binding
IF103_RS14285	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IF103_RS14285	COG0316	Belongs to the HesB IscA family
IF103_RS14290	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IF103_RS14310	COG1879	ABC-type sugar transport system periplasmic component
IF103_RS14330	COG0656	L-ascorbic acid biosynthetic process
IF103_RS14335	COG2814	Major facilitator Superfamily
IF103_RS14375	COG2168	tRNA wobble position uridine thiolation
IF103_RS14385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IF103_RS14390	COG0435	Glutathione S-transferase
IF103_RS14395	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IF103_RS14395	COG1648	precorrin-2 dehydrogenase activity
IF103_RS14400	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IF103_RS14405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IF103_RS14410	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IF103_RS14415	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IF103_RS14420	COG1674	ftsk spoiiie
IF103_RS14425	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IF103_RS14430	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IF103_RS14435	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IF103_RS14440	COG0542	response to heat
IF103_RS14445	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IF103_RS14450	COG1278	Cold shock
IF103_RS14470	COG0482	sulfurtransferase activity
IF103_RS14475	COG2915	High frequency lysogenization protein hflD homolog
IF103_RS14485	COG2850	peptidyl-arginine hydroxylation
IF103_RS14490	COG2153	protein acetylation
IF103_RS14500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IF103_RS14520	COG0583	DNA-binding transcription factor activity
IF103_RS14535	COG2814	Major facilitator Superfamily
IF103_RS14540	COG1064	alcohol dehydrogenase
IF103_RS14545	COG2207	Transcriptional regulator
IF103_RS14560	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IF103_RS14570	COG4774	siderophore transport
IF103_RS14585	COG3064	Membrane
IF103_RS14610	COG2186	Transcriptional regulator
IF103_RS14615	COG0277	FAD linked oxidase domain protein
IF103_RS14620	COG0277	FAD linked oxidase domain protein
IF103_RS14625	COG0247	lactate metabolic process
IF103_RS14630	COG3193	protein, possibly involved in utilization of glycolate and propanediol
IF103_RS14635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IF103_RS14650	COG2807	transmembrane transport
IF103_RS14655	COG0590	tRNA wobble adenosine to inosine editing
IF103_RS14660	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IF103_RS14670	COG0183	Belongs to the thiolase family
IF103_RS14675	COG1250	3-hydroxyacyl-CoA dehydrogenase
IF103_RS14685	COG2205	protein histidine kinase activity
IF103_RS14685	COG0784	Response regulator, receiver
IF103_RS14685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IF103_RS14685	COG2198	Histidine kinase
IF103_RS14690	COG5002	protein histidine kinase activity
IF103_RS14690	COG0784	Response regulator, receiver
IF103_RS14690	COG2205	protein histidine kinase activity
IF103_RS14700	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IF103_RS14740	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IF103_RS14750	COG2066	Belongs to the glutaminase family
IF103_RS14755	COG1686	Belongs to the peptidase S11 family
IF103_RS14795	COG1121	(ABC) transporter
IF103_RS14800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IF103_RS14840	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IF103_RS14855	COG0446	pyridine nucleotide-disulphide oxidoreductase
IF103_RS14855	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IF103_RS14865	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IF103_RS14875	COG0583	DNA-binding transcription factor activity
IF103_RS14890	COG0402	S-adenosylhomocysteine deaminase activity
IF103_RS14900	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IF103_RS14935	COG0583	DNA-binding transcription factor activity
IF103_RS14955	COG0322	excinuclease ABC activity
IF103_RS14990	COG1696	Membrane protein involved in D-alanine export
IF103_RS15035	COG0306	phosphate transporter
IF103_RS15040	COG0625	glutathione transferase activity
IF103_RS15045	COG2050	protein possibly involved in aromatic compounds catabolism
IF103_RS15045	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IF103_RS15050	COG1113	amino acid transport
IF103_RS15055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IF103_RS15070	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IF103_RS15075	COG0659	secondary active sulfate transmembrane transporter activity
IF103_RS15095	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IF103_RS15100	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IF103_RS15105	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IF103_RS15105	COG0649	NAD binding
IF103_RS15120	COG1034	ATP synthesis coupled electron transport
IF103_RS15125	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IF103_RS15130	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IF103_RS15140	COG0713	ATP synthesis coupled electron transport
IF103_RS15155	COG1007	ATP synthesis coupled electron transport
IF103_RS15195	COG0826	peptidase U32
IF103_RS15205	COG1238	metal cluster binding
IF103_RS15210	COG0596	Alpha beta hydrolase
IF103_RS15220	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IF103_RS15225	COG1869	D-ribose catabolic process
IF103_RS15230	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IF103_RS15235	COG1609	Transcriptional regulator
IF103_RS15240	COG1172	Belongs to the binding-protein-dependent transport system permease family
IF103_RS15245	COG1129	ABC transporter
IF103_RS15255	COG0252	asparaginase activity
IF103_RS15265	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IF103_RS15285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IF103_RS15300	COG1253	flavin adenine dinucleotide binding
IF103_RS15310	COG0583	DNA-binding transcription factor activity
IF103_RS15315	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IF103_RS15320	COG3132	Protein of unknown function, DUF480
IF103_RS15330	COG3634	alkyl hydroperoxide reductase activity
IF103_RS15355	COG3258	Cytochrome c
IF103_RS15360	COG2863	cytochrome
IF103_RS15395	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IF103_RS15405	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IF103_RS15410	COG0745	RESPONSE REGULATOR receiver
IF103_RS15415	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
IF103_RS15420	COG4191	Histidine kinase
IF103_RS15420	COG0784	Response regulator, receiver
IF103_RS15435	COG2259	Doxx family
IF103_RS15450	COG0616	signal peptide processing
IF103_RS15470	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS15475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IF103_RS15500	COG0490	domain, Protein
IF103_RS15500	COG0471	metal ion transport
IF103_RS15505	COG2199	diguanylate cyclase activity
IF103_RS15525	COG0840	transmembrane signaling receptor activity
IF103_RS15540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IF103_RS15560	COG1309	transcriptional regulator
IF103_RS15565	COG0604	alcohol dehydrogenase
IF103_RS15580	COG2233	PERMEase
IF103_RS15585	COG2223	nitrite transmembrane transporter activity
IF103_RS15590	COG2207	Transcriptional regulator
IF103_RS15595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IF103_RS15600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IF103_RS15615	COG1131	(ABC) transporter
IF103_RS15620	COG0842	Transport permease protein
IF103_RS15625	COG0842	Transport permease protein
IF103_RS15635	COG0745	RESPONSE REGULATOR receiver
IF103_RS15640	COG2205	protein histidine kinase activity
IF103_RS15645	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IF103_RS15655	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IF103_RS15665	COG0628	permease
IF103_RS15700	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IF103_RS15715	COG3850	Histidine kinase
IF103_RS15715	COG3437	response regulator, receiver
IF103_RS15715	COG2205	protein histidine kinase activity
IF103_RS15715	COG4999	Histidine kinase
IF103_RS15720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IF103_RS15735	COG1741	Belongs to the pirin family
IF103_RS15745	COG0326	Molecular chaperone. Has ATPase activity
IF103_RS15780	COG0045	succinate-CoA ligase (ADP-forming) activity
IF103_RS15785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IF103_RS15805	COG1053	succinate dehydrogenase
IF103_RS15810	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IF103_RS15815	COG2009	succinate dehydrogenase
IF103_RS15840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IF103_RS15845	COG3047	cAMP biosynthetic process
IF103_RS15845	COG2885	chlorophyll binding
IF103_RS15880	COG2944	sequence-specific DNA binding
IF103_RS15890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IF103_RS15890	COG2205	protein histidine kinase activity
IF103_RS15890	COG0784	Response regulator, receiver
IF103_RS15890	COG2198	Histidine kinase
IF103_RS15900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IF103_RS15905	COG1136	(ABC) transporter
IF103_RS15905	COG0577	efflux transmembrane transporter activity
IF103_RS15980	COG0642	Histidine kinase
IF103_RS15995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IF103_RS16030	COG3123	guanosine phosphorylase activity
IF103_RS16040	COG3278	Belongs to the heme-copper respiratory oxidase family
IF103_RS16055	COG2010	Cytochrome c
IF103_RS16060	COG3278	Belongs to the heme-copper respiratory oxidase family
IF103_RS16075	COG2010	Cytochrome c
IF103_RS16080	COG0348	domain, Protein
IF103_RS16090	COG2217	Heavy metal translocating P-type atpase
IF103_RS16110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IF103_RS16115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IF103_RS16120	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IF103_RS16125	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IF103_RS16130	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IF103_RS16150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IF103_RS16155	COG3115	cell septum assembly
IF103_RS16185	COG0402	S-adenosylhomocysteine deaminase activity
IF103_RS16195	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IF103_RS16205	COG2252	PERMEase
IF103_RS16225	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IF103_RS16235	COG2233	PERMEase
IF103_RS16250	COG2354	Protein conserved in bacteria
IF103_RS16265	COG3960	tartronate-semialdehyde synthase activity
IF103_RS16270	COG3622	Belongs to the hyi family
IF103_RS16275	COG2084	Dehydrogenase
IF103_RS16285	COG0469	pyruvate kinase activity
IF103_RS16290	COG4413	Urea transporter
IF103_RS16300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IF103_RS16310	COG0116	Belongs to the methyltransferase superfamily
IF103_RS16310	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IF103_RS16320	COG1522	sequence-specific DNA binding
IF103_RS16325	COG1953	Uracil, thiamine, allantoin
IF103_RS16425	COG3209	COG3209 Rhs family protein
IF103_RS16490	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IF103_RS16515	COG1138	Cytochrome C-type biogenesis protein
IF103_RS16520	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IF103_RS16540	COG4133	protoheme IX ABC transporter activity
IF103_RS16550	COG2257	FlhB HrpN YscU SpaS Family
IF103_RS16565	COG0835	chemotaxis
IF103_RS16575	COG1192	Involved in chromosome partitioning
IF103_RS16580	COG1360	Flagellar Motor Protein
IF103_RS16585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IF103_RS16590	COG2201	protein-glutamate methylesterase activity
IF103_RS16595	COG0784	Response regulator, receiver
IF103_RS16595	COG0643	Histidine kinase
IF103_RS16595	COG2198	Histidine kinase
IF103_RS16600	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IF103_RS16625	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IF103_RS16690	COG2882	bacterial-type flagellum organization
IF103_RS16715	COG1677	Flagellar hook-basal body complex protein FliE
IF103_RS16755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IF103_RS16770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IF103_RS16775	COG2089	acid synthase
IF103_RS16780	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IF103_RS16785	COG1083	cytidylyl-transferase
IF103_RS16790	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IF103_RS16795	COG1086	Polysaccharide biosynthesis protein
IF103_RS16800	COG0438	transferase activity, transferring glycosyl groups
IF103_RS16800	COG1216	Glycosyl transferase, family 2
IF103_RS16825	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
IF103_RS16835	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IF103_RS16840	COG1216	Glycosyl transferase, family 2
IF103_RS16840	COG0438	transferase activity, transferring glycosyl groups
IF103_RS16850	COG1256	bacterial-type flagellum assembly
IF103_RS16860	COG1706	bacterial-type flagellum-dependent cell motility
IF103_RS16865	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IF103_RS16875	COG4787	bacterial-type flagellum-dependent cell motility
IF103_RS16885	COG1749	Flagellar hook protein flgE
IF103_RS16900	COG1815	bacterial-type flagellum-dependent cell motility
IF103_RS16905	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IF103_RS16910	COG0835	chemotaxis
IF103_RS16910	COG0784	Response regulator, receiver
IF103_RS16930	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
IF103_RS16940	COG0477	Major facilitator Superfamily
IF103_RS16950	COG1522	sequence-specific DNA binding
IF103_RS16955	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IF103_RS16960	COG0022	dehydrogenase e1 component
IF103_RS16970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IF103_RS17005	COG2239	Acts as a magnesium transporter
IF103_RS17035	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IF103_RS17040	COG0527	aspartate kinase activity
IF103_RS17045	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IF103_RS17050	COG2988	succinylglutamate desuccinylase activity
IF103_RS17060	COG3724	N-succinylarginine dihydrolase activity
IF103_RS17065	COG1012	belongs to the aldehyde dehydrogenase family
IF103_RS17080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IF103_RS17105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IF103_RS17110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IF103_RS17130	COG2154	pterin-4-alpha-carbinolamine dehydratase
IF103_RS17140	COG0247	lactate metabolic process
IF103_RS17140	COG0277	FAD linked oxidase domain protein
IF103_RS17145	COG0583	DNA-binding transcription factor activity
IF103_RS17150	COG1113	amino acid transport
IF103_RS17160	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IF103_RS17170	COG0009	L-threonylcarbamoyladenylate synthase
IF103_RS17175	COG0613	PHP domain protein
IF103_RS17180	COG2917	probably involved in intracellular septation
IF103_RS17185	COG2350	Protein conserved in bacteria
IF103_RS17195	COG0745	RESPONSE REGULATOR receiver
IF103_RS17205	COG0642	Histidine kinase
IF103_RS17210	COG0778	Nitroreductase
IF103_RS17215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IF103_RS17235	COG2207	Transcriptional regulator
IF103_RS17250	COG1752	Esterase of the alpha-beta hydrolase superfamily
IF103_RS17260	COG0514	ATP-dependent DNA helicase (RecQ)
IF103_RS17270	COG2832	Protein of unknown function (DUF454)
IF103_RS17290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IF103_RS17315	COG1305	Transglutaminase-like
IF103_RS17325	COG2308	Evidence 4 Homologs of previously reported genes of
IF103_RS17335	COG0840	transmembrane signaling receptor activity
IF103_RS17350	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IF103_RS17355	COG0583	DNA-binding transcription factor activity
IF103_RS17365	COG0697	spore germination
IF103_RS17375	COG0513	Belongs to the DEAD box helicase family
IF103_RS17380	COG0668	transmembrane transport
IF103_RS17390	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IF103_RS17405	COG2267	carboxylic ester hydrolase activity
IF103_RS17415	COG1132	(ABC) transporter
IF103_RS17425	COG2188	Transcriptional regulator
IF103_RS17435	COG1643	Atp-dependent helicase
IF103_RS17440	COG0174	glutamine synthetase
IF103_RS17445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IF103_RS17450	COG0318	PFAM AMP-dependent synthetase and ligase
IF103_RS17465	COG2030	dehydratase
IF103_RS17470	COG4941	Belongs to the sigma-70 factor family
IF103_RS17480	COG3795	YCII-related domain
IF103_RS17500	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IF103_RS17505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IF103_RS17520	COG0242	peptide deformylase activity
IF103_RS17525	COG1295	ribonuclease BN
IF103_RS17535	COG3420	alginic acid biosynthetic process
IF103_RS17545	COG2996	Protein conserved in bacteria
IF103_RS17555	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
IF103_RS17565	COG1116	anion transmembrane transporter activity
IF103_RS17575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IF103_RS17580	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS17595	COG1414	Transcriptional regulator
IF103_RS17600	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS17615	COG1012	belongs to the aldehyde dehydrogenase family
IF103_RS17665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IF103_RS17685	COG1984	allophanate hydrolase subunit 2
IF103_RS17690	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IF103_RS17695	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IF103_RS17700	COG2814	Major facilitator Superfamily
IF103_RS17705	COG0583	DNA-binding transcription factor activity
IF103_RS17715	COG0121	glutamine amidotransferase
IF103_RS17755	COG2983	Belongs to the UPF0260 family
IF103_RS17765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IF103_RS17770	COG3100	YcgL domain-containing protein
IF103_RS17780	COG2194	sulfuric ester hydrolase activity
IF103_RS17795	COG0626	cystathionine gamma-synthase activity
IF103_RS17800	COG1522	sequence-specific DNA binding
IF103_RS17805	COG0243	molybdopterin cofactor binding
IF103_RS17810	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IF103_RS17815	COG3781	membrane
IF103_RS17820	COG0521	Mo-molybdopterin cofactor biosynthetic process
IF103_RS17825	COG0583	DNA-binding transcription factor activity
IF103_RS17835	COG0531	amino acid
IF103_RS17840	COG3938	Belongs to the proline racemase family
IF103_RS17845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IF103_RS17855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IF103_RS17860	COG1902	pentaerythritol trinitrate reductase activity
IF103_RS17865	COG0640	Transcriptional regulator
IF103_RS17870	COG0579	oxidoreductase
IF103_RS17885	COG2271	Major facilitator Superfamily
IF103_RS17890	COG1012	belongs to the aldehyde dehydrogenase family
IF103_RS17905	COG0129	dihydroxy-acid dehydratase activity
IF103_RS17935	COG1477	protein flavinylation
IF103_RS17960	COG0302	gtp cyclohydrolase
IF103_RS17975	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IF103_RS17980	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IF103_RS17985	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IF103_RS17990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IF103_RS18000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IF103_RS18010	COG0425	Belongs to the sulfur carrier protein TusA family
IF103_RS18020	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IF103_RS18030	COG0531	amino acid
IF103_RS18035	COG0840	transmembrane signaling receptor activity
IF103_RS18065	COG3436	PFAM IS66 Orf2 family protein
IF103_RS18095	COG3121	Chaperone
IF103_RS18105	COG2205	protein histidine kinase activity
IF103_RS18105	COG0784	Response regulator, receiver
IF103_RS18110	COG0784	Response regulator, receiver
IF103_RS18110	COG2205	protein histidine kinase activity
IF103_RS18110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IF103_RS18110	COG2198	Histidine kinase
IF103_RS18115	COG2197	response regulator
IF103_RS18120	COG5001	Diguanylate cyclase
IF103_RS18120	COG3300	MHYT domain
IF103_RS18150	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IF103_RS18155	COG0602	queuosine metabolic process
IF103_RS18160	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IF103_RS18165	COG2885	chlorophyll binding
IF103_RS18170	COG0823	Involved in the tonB-independent uptake of proteins
IF103_RS18190	COG0824	Thioesterase
IF103_RS18195	COG2255	four-way junction helicase activity
IF103_RS18200	COG0632	four-way junction helicase activity
IF103_RS18205	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IF103_RS18210	COG0217	transcriptional regulatory protein
IF103_RS18215	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IF103_RS18230	COG0783	Belongs to the Dps family
IF103_RS18240	COG2900	Belongs to the SlyX family
IF103_RS18255	COG0442	prolyl-tRNA aminoacylation
IF103_RS18265	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IF103_RS18290	COG3158	transport of potassium into the cell
IF103_RS18295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IF103_RS18310	COG4807	Protein conserved in bacteria
IF103_RS18325	COG0583	DNA-binding transcription factor activity
IF103_RS18340	COG3148	PFAM DTW domain containing protein
IF103_RS18360	COG2137	regulation of response to DNA damage stimulus
IF103_RS18365	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IF103_RS18370	COG1546	Belongs to the CinA family
IF103_RS18375	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IF103_RS18380	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IF103_RS18395	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IF103_RS18400	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IF103_RS18405	COG0585	pseudouridine synthase activity
IF103_RS18410	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IF103_RS18420	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IF103_RS18430	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IF103_RS18440	COG0148	phosphopyruvate hydratase activity
IF103_RS18445	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IF103_RS18450	COG0504	CTP synthase activity
IF103_RS18455	COG0037	tRNA processing
IF103_RS18460	COG0825	malonyl-CoA metabolic process
IF103_RS18470	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IF103_RS18475	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IF103_RS18480	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IF103_RS18485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IF103_RS18490	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IF103_RS18500	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IF103_RS18510	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IF103_RS18520	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IF103_RS18525	COG0233	cytoplasmic translational termination
IF103_RS18530	COG0528	UMP kinase activity
IF103_RS18535	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IF103_RS18540	COG0052	Belongs to the universal ribosomal protein uS2 family
IF103_RS18545	COG0024	Methionine aminopeptidase
IF103_RS18550	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IF103_RS18555	COG0436	Aminotransferase
IF103_RS18560	COG0025	NhaP-type Na H and K H
IF103_RS18565	COG1393	Belongs to the ArsC family
IF103_RS18570	COG2171	N-acyltransferase activity
IF103_RS18575	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IF103_RS18580	COG2166	iron-sulfur cluster assembly
IF103_RS18585	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IF103_RS18590	COG1215	transferase activity, transferring glycosyl groups
IF103_RS18595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IF103_RS18600	COG2226	methyltransferase
IF103_RS18615	COG2937	Belongs to the GPAT DAPAT family
IF103_RS18635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IF103_RS18650	COG0742	ribosomal rna small subunit methyltransferase
IF103_RS18685	COG0563	adenylate kinase activity
IF103_RS18690	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IF103_RS18705	COG3047	cAMP biosynthetic process
IF103_RS18705	COG2885	chlorophyll binding
IF103_RS18715	COG1073	alpha beta
IF103_RS18735	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IF103_RS18745	COG2203	Gaf domain
IF103_RS18745	COG5001	Diguanylate cyclase
IF103_RS18745	COG3706	GGDEF domain
IF103_RS18745	COG4251	negative regulation of phosphorylation
IF103_RS18750	COG2201	protein-glutamate methylesterase activity
IF103_RS18765	COG0457	Tetratricopeptide repeat
IF103_RS18765	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IF103_RS18775	COG0840	transmembrane signaling receptor activity
IF103_RS18780	COG2979	Protein of unknown function (DUF533)
IF103_RS18785	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IF103_RS18790	COG3842	ATPase activity
IF103_RS18795	COG1176	ABC-type spermidine putrescine transport system, permease component I
IF103_RS18800	COG1177	transmembrane transport
IF103_RS18805	COG1012	belongs to the aldehyde dehydrogenase family
IF103_RS18810	COG1902	pentaerythritol trinitrate reductase activity
IF103_RS18825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IF103_RS18860	COG4974	Belongs to the 'phage' integrase family
IF103_RS18870	COG1607	acyl-coa hydrolase
IF103_RS18875	COG0335	large ribosomal subunit rRNA binding
IF103_RS18880	COG0336	Belongs to the RNA methyltransferase TrmD family
IF103_RS18885	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IF103_RS18890	COG0228	four-way junction DNA binding
IF103_RS18895	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IF103_RS18905	COG4536	flavin adenine dinucleotide binding
IF103_RS18910	COG0477	Major facilitator Superfamily
IF103_RS18915	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IF103_RS18945	COG3034	peptidoglycan biosynthetic process
IF103_RS18990	COG2165	general secretion pathway protein
IF103_RS19000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IF103_RS19030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IF103_RS19035	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IF103_RS19055	COG0047	phosphoribosylformylglycinamidine synthase activity
IF103_RS19055	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IF103_RS19060	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IF103_RS19065	COG0590	tRNA wobble adenosine to inosine editing
IF103_RS19075	COG0519	Catalyzes the synthesis of GMP from XMP
IF103_RS19075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IF103_RS19095	COG1570	exodeoxyribonuclease VII activity
IF103_RS19100	COG0739	heme binding
IF103_RS19105	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IF103_RS19110	COG0800	Aldolase
IF103_RS19125	COG1737	Transcriptional regulator
IF103_RS19130	COG0676	glucose-6-phosphate 1-epimerase activity
IF103_RS19140	COG3842	ATPase activity
IF103_RS19150	COG1175	transmembrane transport
IF103_RS19155	COG1653	transport
IF103_RS19210	COG2832	Protein of unknown function (DUF454)
IF103_RS19225	COG2235	arginine
IF103_RS19230	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IF103_RS19250	COG0509	glycine decarboxylation via glycine cleavage system
IF103_RS19255	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IF103_RS19255	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IF103_RS19260	COG1760	l-serine dehydratase
IF103_RS19265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IF103_RS19270	COG1278	Cold shock
IF103_RS19280	COG0795	lipopolysaccharide-transporting ATPase activity
IF103_RS19285	COG0795	lipopolysaccharide-transporting ATPase activity
IF103_RS19290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IF103_RS19305	COG0525	valine-tRNA ligase activity
IF103_RS19310	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
IF103_RS19315	COG0776	regulation of translation
IF103_RS19320	COG3081	Nucleoid-associated protein
IF103_RS19325	COG2827	Endonuclease containing a URI domain
IF103_RS19335	COG2807	transmembrane transport
IF103_RS19340	COG2186	Transcriptional regulator
IF103_RS19350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IF103_RS19355	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IF103_RS19360	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IF103_RS19365	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IF103_RS19385	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IF103_RS19390	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IF103_RS19395	COG1127	ABC transporter
IF103_RS19405	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IF103_RS19415	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IF103_RS19420	COG1137	ATPase activity
IF103_RS19425	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IF103_RS19430	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IF103_RS19440	COG1660	Displays ATPase and GTPase activities
IF103_RS19445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IF103_RS19460	COG0312	modulator of DNA gyrase
IF103_RS19465	COG3028	Belongs to the UPF0307 family
IF103_RS19470	COG0312	modulator of DNA gyrase
IF103_RS19475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IF103_RS19490	COG0424	maF-like protein
IF103_RS19495	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IF103_RS19500	COG1792	Involved in formation and maintenance of cell shape
IF103_RS19505	COG1077	Cell shape determining protein MreB Mrl
IF103_RS19510	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IF103_RS19515	COG0154	amidase activity
IF103_RS19520	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IF103_RS19535	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IF103_RS19540	COG1113	amino acid transport
IF103_RS19550	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IF103_RS19565	COG0747	negative chemotaxis
IF103_RS19570	COG0747	negative chemotaxis
IF103_RS19580	COG0747	negative chemotaxis
IF103_RS19585	COG0601	transmembrane transport
IF103_RS19590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IF103_RS19595	COG0444	Belongs to the ABC transporter superfamily
IF103_RS19600	COG4608	Belongs to the ABC transporter superfamily
IF103_RS19615	COG0723	plastoquinol--plastocyanin reductase activity
IF103_RS19615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IF103_RS19630	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IF103_RS19660	COG4772	TonB-dependent receptor
IF103_RS19675	COG0019	diaminopimelate decarboxylase activity
IF103_RS19690	COG3128	pkhd-type hydroxylase
IF103_RS19695	COG4774	siderophore transport
IF103_RS19705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IF103_RS19710	COG0436	Aminotransferase
IF103_RS19715	COG1160	GTP binding
IF103_RS19730	COG0124	histidyl-tRNA synthetase
IF103_RS19735	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IF103_RS19750	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IF103_RS19755	COG0105	UTP biosynthetic process
IF103_RS19765	COG0633	Ferredoxin
IF103_RS19770	COG0443	Heat shock 70 kDa protein
IF103_RS19775	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IF103_RS19780	COG0316	Belongs to the HesB IscA family
IF103_RS19790	COG1104	cysteine desulfurase activity
IF103_RS19800	COG1045	serine acetyltransferase
IF103_RS19815	COG3134	Outer membrane lipoprotein
IF103_RS19830	COG1862	Preprotein translocase
IF103_RS19835	COG0343	queuine tRNA-ribosyltransferase activity
IF103_RS19840	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IF103_RS19860	COG3781	membrane
IF103_RS19865	COG3639	organic phosphonate transmembrane transporter activity
IF103_RS19870	COG3639	organic phosphonate transmembrane transporter activity
IF103_RS19875	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IF103_RS19880	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IF103_RS19885	COG0709	Synthesizes selenophosphate from selenide and ATP
IF103_RS19890	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
IF103_RS19905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IF103_RS19910	COG0727	PFAM Uncharacterised protein family (UPF0153)
IF103_RS19915	COG0436	Aminotransferase
IF103_RS19920	COG0109	protoheme IX farnesyltransferase activity
IF103_RS19930	COG1845	cytochrome c oxidase, subunit III
IF103_RS19935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IF103_RS19940	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IF103_RS19945	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IF103_RS19950	COG1017	nitric oxide dioxygenase activity
IF103_RS19950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IF103_RS19955	COG3604	Transcriptional regulator
IF103_RS19970	COG2274	protein secretion by the type I secretion system
IF103_RS20120	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IF103_RS20130	COG0642	Histidine kinase
IF103_RS20145	COG5001	Diguanylate cyclase
IF103_RS20145	COG3706	GGDEF domain
IF103_RS20145	COG4251	negative regulation of phosphorylation
IF103_RS20145	COG2203	Gaf domain
IF103_RS20155	COG3530	Putative quorum-sensing-regulated virulence factor
IF103_RS20160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IF103_RS20160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IF103_RS20160	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IF103_RS20165	COG1105	Belongs to the carbohydrate kinase PfkB family
IF103_RS20175	COG1609	Transcriptional regulator
IF103_RS20180	COG0084	hydrolase, TatD family'
IF103_RS20185	COG0840	transmembrane signaling receptor activity
IF103_RS20190	COG3725	Membrane protein required for beta-lactamase induction
IF103_RS20195	COG3023	N-Acetylmuramoyl-L-alanine amidase
IF103_RS20210	COG0492	ferredoxin-NADP+ reductase activity
IF103_RS20215	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
IF103_RS20235	COG0386	Belongs to the glutathione peroxidase family
IF103_RS20240	COG1047	Peptidyl-prolyl cis-trans
IF103_RS20250	COG0280	phosphate acetyltransferase
IF103_RS20250	COG0857	belongs to the CobB CobQ family
IF103_RS20255	COG2885	chlorophyll binding
IF103_RS20260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IF103_RS20290	COG0318	PFAM AMP-dependent synthetase and ligase
IF103_RS20295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IF103_RS20300	COG2813	Specifically methylates the guanine in position
IF103_RS20305	COG2119	membrane
IF103_RS20310	COG0501	Belongs to the peptidase M48B family
IF103_RS20315	COG2135	peptidase activity
IF103_RS20345	COG0579	oxidoreductase
IF103_RS20365	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IF103_RS20370	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IF103_RS20380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IF103_RS20385	COG1090	epimerase
IF103_RS20390	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
IF103_RS20395	COG3272	Protein of unknown function (DUF1722)
IF103_RS20400	COG0789	Transcriptional regulator
IF103_RS20420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IF103_RS20425	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IF103_RS20435	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IF103_RS20440	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IF103_RS20450	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IF103_RS20455	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IF103_RS20465	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IF103_RS20470	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IF103_RS20475	COG0193	aminoacyl-tRNA hydrolase activity
IF103_RS20500	COG1538	Outer membrane efflux protein
IF103_RS20505	COG0628	permease
IF103_RS20520	COG1335	isochorismatase
IF103_RS20540	COG1511	domain protein
IF103_RS20540	COG3264	Mechanosensitive ion channel
IF103_RS20545	COG2169	Transcriptional regulator
IF103_RS20545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IF103_RS20555	COG1595	DNA-templated transcription, initiation
IF103_RS20560	COG3712	iron ion homeostasis
IF103_RS20580	COG2223	nitrite transmembrane transporter activity
IF103_RS20615	COG0456	acetyltransferase
IF103_RS20640	COG3045	CreA protein
IF103_RS20645	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IF103_RS20650	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IF103_RS20655	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IF103_RS20660	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IF103_RS20665	COG0142	geranyltranstransferase activity
IF103_RS20670	COG2824	Alkylphosphonate utilization operon protein PhnA
IF103_RS20680	COG0545	Peptidyl-prolyl cis-trans isomerase
IF103_RS20690	COG2862	Uncharacterized protein family, UPF0114
IF103_RS20700	COG1067	ATP-dependent peptidase activity
IF103_RS20720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IF103_RS20725	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IF103_RS20730	COG0488	(ABC) transporter
IF103_RS20745	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IF103_RS20765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IF103_RS20770	COG0765	amino acid transport
IF103_RS20775	COG0431	NADPH-dependent FMN reductase
IF103_RS20785	COG0640	Transcriptional regulator
IF103_RS20840	COG0582	viral genome integration into host DNA
IF103_RS20865	COG0237	dephospho-CoA kinase activity
IF103_RS20870	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IF103_RS20890	COG1252	NADH dehydrogenase
IF103_RS20910	COG0542	response to heat
IF103_RS20950	COG1172	Belongs to the binding-protein-dependent transport system permease family
IF103_RS20975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IF103_RS21005	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IF103_RS21010	COG1047	Peptidyl-prolyl cis-trans
IF103_RS21015	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IF103_RS21020	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IF103_RS21025	COG0196	riboflavin kinase activity
IF103_RS21035	COG0268	Binds directly to 16S ribosomal RNA
IF103_RS21040	COG3008	intermembrane lipid transfer
IF103_RS21045	COG2995	paraquat-inducible protein a
IF103_RS21050	COG2995	paraquat-inducible protein a
IF103_RS21095	COG1309	transcriptional regulator
IF103_RS21100	COG1739	Uncharacterized protein family UPF0029
IF103_RS21105	COG0300	oxidoreductase activity
IF103_RS21115	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IF103_RS21125	COG2814	Major facilitator Superfamily
IF103_RS21140	COG2217	Heavy metal translocating P-type atpase
IF103_RS21150	COG0840	transmembrane signaling receptor activity
IF103_RS21155	COG2207	Transcriptional regulator
IF103_RS21165	COG1028	Short-chain dehydrogenase reductase Sdr
IF103_RS21180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IF103_RS21210	COG4953	penicillin-binding protein 1C
IF103_RS21220	COG2373	Large extracellular alpha-helical protein
IF103_RS21225	COG0534	Mate efflux family protein
IF103_RS21235	COG1166	arginine decarboxylase activity
IF103_RS21240	COG0023	Translation Initiation Factor
IF103_RS21270	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IF103_RS21285	COG3284	Transcriptional regulator
IF103_RS21290	COG3199	ATP-NAD kinase
IF103_RS21295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IF103_RS21300	COG0022	dehydrogenase e1 component
IF103_RS21310	COG1063	alcohol dehydrogenase
IF103_RS21315	COG1619	proteins homologs of microcin C7 resistance protein MccF
IF103_RS21320	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IF103_RS21325	COG0321	lipoyl(octanoyl) transferase activity
IF103_RS21330	COG2921	Belongs to the UPF0250 family
IF103_RS21335	COG1686	Belongs to the peptidase S11 family
IF103_RS21345	COG2951	lytic endotransglycosylase activity
IF103_RS21350	COG0772	Belongs to the SEDS family
IF103_RS21355	COG0768	penicillin binding
IF103_RS21360	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IF103_RS21370	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IF103_RS21375	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IF103_RS21380	COG2094	Belongs to the DNA glycosylase MPG family
IF103_RS21385	COG0586	Pfam SNARE associated Golgi protein
IF103_RS21395	COG1346	cytolysis
IF103_RS21415	COG0702	epimerase
IF103_RS21430	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IF103_RS21435	COG3284	Transcriptional regulator
IF103_RS21445	COG0531	amino acid
IF103_RS21450	COG4303	Ethanolamine ammonia lyase large subunit
IF103_RS21455	COG4302	ethanolamine ammonia-lyase activity
IF103_RS21460	COG0456	acetyltransferase
IF103_RS21465	COG0586	Pfam SNARE associated Golgi protein
IF103_RS21475	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IF103_RS21565	COG2132	Multicopper oxidase
IF103_RS21585	COG1113	amino acid transport
IF103_RS21600	COG0579	oxidoreductase
IF103_RS21610	COG1802	Transcriptional regulator
IF103_RS21615	COG1690	Belongs to the RtcB family
IF103_RS21620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IF103_RS21625	COG1722	exodeoxyribonuclease VII activity
IF103_RS21630	COG0142	geranyltranstransferase activity
IF103_RS21635	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IF103_RS21640	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IF103_RS21650	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IF103_RS21660	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IF103_RS21670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IF103_RS21675	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IF103_RS21690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IF103_RS21690	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IF103_RS21695	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IF103_RS21705	COG2264	protein methyltransferase activity
IF103_RS21710	COG3118	belongs to the thioredoxin family
IF103_RS21745	COG3047	cAMP biosynthetic process
IF103_RS21750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IF103_RS21765	COG1115	amino acid carrier protein
IF103_RS21770	COG0252	asparaginase activity
IF103_RS21780	COG3276	selenocysteine insertion sequence binding
IF103_RS21785	COG1921	L-seryl-tRNASec selenium transferase activity
IF103_RS21790	COG3058	Necessary for formate dehydrogenase activity
IF103_RS21795	COG2864	formate dehydrogenase
IF103_RS21800	COG0437	4 iron, 4 sulfur cluster binding
IF103_RS21810	COG4221	oxidoreductase activity
IF103_RS21825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IF103_RS21830	COG0629	single-stranded DNA binding
IF103_RS21835	COG2814	Major facilitator Superfamily
IF103_RS21840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IF103_RS21845	COG2193	ferroxidase activity
IF103_RS21850	COG0753	catalase activity
IF103_RS21855	COG0203	ribosomal protein L17
IF103_RS21860	COG0202	RNA polymerase activity
IF103_RS21865	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IF103_RS21870	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IF103_RS21875	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IF103_RS21880	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IF103_RS21890	COG0200	Binds to the 23S rRNA
IF103_RS21895	COG1841	ribosomal large subunit assembly
IF103_RS21900	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IF103_RS21905	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IF103_RS21910	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IF103_RS21915	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IF103_RS21920	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IF103_RS21925	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IF103_RS21930	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IF103_RS21935	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IF103_RS21940	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IF103_RS21945	COG0255	Belongs to the universal ribosomal protein uL29 family
IF103_RS21950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IF103_RS21955	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IF103_RS21960	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IF103_RS21965	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IF103_RS21970	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IF103_RS21975	COG0089	rRNA binding
IF103_RS21980	COG0088	Forms part of the polypeptide exit tunnel
IF103_RS21985	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IF103_RS21990	COG0051	transcription antitermination factor activity, RNA binding
IF103_RS21995	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IF103_RS22000	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IF103_RS22005	COG0049	tRNA binding
IF103_RS22010	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IF103_RS22015	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IF103_RS22020	COG0085	RNA polymerase activity
IF103_RS22030	COG0222	ribosome binding
IF103_RS22035	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IF103_RS22040	COG0081	regulation of translation
IF103_RS22045	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IF103_RS22065	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IF103_RS22090	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IF103_RS22095	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IF103_RS22095	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IF103_RS22125	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IF103_RS22130	COG0739	heme binding
IF103_RS22135	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IF103_RS22140	COG0316	Belongs to the HesB IscA family
IF103_RS22145	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IF103_RS22150	COG1981	membrane
IF103_RS22160	COG0300	oxidoreductase activity
IF103_RS22165	COG0537	adenosine 5'-monophosphoramidase activity
IF103_RS22170	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
IF103_RS22180	COG1765	OsmC-like protein
IF103_RS22195	COG0134	indole-3-glycerol-phosphate synthase activity
IF103_RS22200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IF103_RS22205	COG0512	Glutamine amidotransferase of anthranilate synthase
IF103_RS22210	COG3240	lipase activity
IF103_RS22210	COG4625	pathogenesis
IF103_RS22215	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IF103_RS22220	COG0546	phosphoglycolate phosphatase activity
IF103_RS22225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IF103_RS22235	COG1176	ABC-type spermidine putrescine transport system, permease component I
IF103_RS22245	COG3842	ATPase activity
IF103_RS22250	COG2197	response regulator
IF103_RS22255	COG4585	Histidine kinase
IF103_RS22265	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IF103_RS22270	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IF103_RS22275	COG3178	'Phosphotransferase
IF103_RS22280	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IF103_RS22285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IF103_RS22290	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IF103_RS22295	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IF103_RS22300	COG2967	ApaG domain
IF103_RS22305	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IF103_RS22310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IF103_RS22315	COG2766	serine protein kinase
IF103_RS22320	COG2718	Belongs to the UPF0229 family
IF103_RS22325	COG2719	SpoVR family
IF103_RS22330	COG0617	tRNA 3'-terminal CCA addition
IF103_RS22340	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IF103_RS22345	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IF103_RS22350	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IF103_RS22355	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IF103_RS22360	COG0358	DNA primase activity
IF103_RS22450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IF103_RS22455	COG1025	Belongs to the peptidase M16 family
IF103_RS22465	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IF103_RS22470	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
IF103_RS22480	COG0535	radical SAM domain protein
IF103_RS22495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IF103_RS22500	COG0583	DNA-binding transcription factor activity
IF103_RS22505	COG1960	acyl-CoA dehydrogenase activity
IF103_RS22510	COG3706	GGDEF domain
IF103_RS22515	COG1960	acyl-CoA dehydrogenase activity
IF103_RS22540	COG0156	8-amino-7-oxononanoate synthase activity
IF103_RS22545	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IF103_RS22550	COG1040	competence protein
IF103_RS22555	COG2005	Transcriptional regulator
IF103_RS22555	COG3585	molybdate ion transport
IF103_RS22575	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IF103_RS22590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IF103_RS22595	COG1595	DNA-templated transcription, initiation
IF103_RS22600	COG3712	iron ion homeostasis
IF103_RS22605	COG4774	siderophore transport
IF103_RS22645	COG0438	transferase activity, transferring glycosyl groups
IF103_RS22660	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IF103_RS22680	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IF103_RS22695	COG0204	Acyl-transferase
IF103_RS22700	COG0531	amino acid
IF103_RS22735	COG1063	alcohol dehydrogenase
IF103_RS22765	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IF103_RS22780	COG0840	transmembrane signaling receptor activity
IF103_RS22800	COG1017	nitric oxide dioxygenase activity
IF103_RS22800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IF103_RS22825	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
IF103_RS22830	COG2181	nitrate reductase activity
IF103_RS22830	COG0247	lactate metabolic process
IF103_RS22835	COG1902	pentaerythritol trinitrate reductase activity
IF103_RS22835	COG0446	pyridine nucleotide-disulphide oxidoreductase
IF103_RS22865	COG3246	L-lysine catabolic process to acetate
IF103_RS22870	COG1250	3-hydroxyacyl-CoA dehydrogenase
IF103_RS22890	COG1760	l-serine dehydratase
IF103_RS22900	COG4176	ABC-type proline glycine betaine transport system permease component
IF103_RS22905	COG4175	Glycine betaine
IF103_RS22910	COG0107	imidazoleglycerol-phosphate synthase activity
IF103_RS22915	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IF103_RS22925	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IF103_RS22930	COG0131	Imidazoleglycerol-phosphate dehydratase
IF103_RS22935	COG2223	nitrite transmembrane transporter activity
IF103_RS22950	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IF103_RS22985	COG4215	(ABC) transporter
IF103_RS23030	COG4695	Portal protein
IF103_RS23270	COG0582	viral genome integration into host DNA
IF103_RS23280	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IF103_RS23285	COG0210	DNA helicase
IF103_RS23295	COG2026	Addiction module toxin, RelE StbE family
IF103_RS23320	COG0069	glutamate synthase activity
IF103_RS23330	COG2957	Belongs to the agmatine deiminase family
IF103_RS23360	COG0494	nUDIX hydrolase
IF103_RS23365	COG1011	Hydrolase
IF103_RS23370	COG1652	LysM domain
IF103_RS23375	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IF103_RS23380	COG0243	molybdopterin cofactor binding
IF103_RS23395	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IF103_RS23400	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IF103_RS23410	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IF103_RS23415	COG0189	ligase activity
IF103_RS23415	COG4067	protein conserved in archaea
IF103_RS23420	COG0189	ligase activity
IF103_RS23435	COG2183	response to ionizing radiation
IF103_RS23445	COG2918	glutathione biosynthetic process
IF103_RS23460	COG1116	anion transmembrane transporter activity
IF103_RS23465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IF103_RS23470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IF103_RS23475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IF103_RS23480	COG0431	NADPH-dependent FMN reductase
IF103_RS23485	COG0450	alkyl hydroperoxide reductase
IF103_RS23495	COG4521	taurine ABC transporter
IF103_RS23500	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IF103_RS23505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IF103_RS23510	COG2175	clavaminate synthase activity
IF103_RS23515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IF103_RS23520	COG1045	serine acetyltransferase
IF103_RS23525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IF103_RS23530	COG0765	amino acid transport
IF103_RS23535	COG1126	abc transporter atp-binding protein
IF103_RS23540	COG3204	pilus organization
IF103_RS23545	COG3204	pilus organization
IF103_RS23550	COG0179	Fumarylacetoacetate (FAA) hydrolase
IF103_RS23555	COG0277	FAD linked oxidase domain protein
IF103_RS23560	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IF103_RS23625	COG3829	transcription factor binding
IF103_RS23635	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IF103_RS23640	COG4208	sulfate ABC transporter
IF103_RS23650	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IF103_RS23660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IF103_RS23675	COG1177	transmembrane transport
IF103_RS23680	COG1176	ABC-type spermidine putrescine transport system, permease component I
IF103_RS23685	COG3842	ATPase activity
IF103_RS23705	COG0174	glutamine synthetase
IF103_RS23710	COG0174	glutamine synthetase
IF103_RS23715	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IF103_RS23715	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IF103_RS23720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IF103_RS23730	COG1522	sequence-specific DNA binding
IF103_RS23750	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IF103_RS23750	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IF103_RS23755	COG0509	glycine decarboxylation via glycine cleavage system
IF103_RS23760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IF103_RS23765	COG1178	ABC-type Fe3 transport system permease component
IF103_RS23775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IF103_RS23785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IF103_RS23790	COG0006	proline dipeptidase activity
IF103_RS23795	COG3079	Belongs to the UPF0149 family
IF103_RS23815	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IF103_RS23850	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IF103_RS23865	COG0248	Ppx GppA phosphatase
IF103_RS23870	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IF103_RS23875	COG0586	Pfam SNARE associated Golgi protein
IF103_RS23885	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IF103_RS23890	COG1671	Belongs to the UPF0178 family
IF103_RS23895	COG0672	)-iron permease
IF103_RS23915	COG1289	transmembrane transporter activity
IF103_RS23935	COG1335	isochorismatase
IF103_RS23940	COG0583	DNA-binding transcription factor activity
IF103_RS23965	COG1335	isochorismatase
IF103_RS23985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IF103_RS23990	COG1012	belongs to the aldehyde dehydrogenase family
IF103_RS23995	COG0583	DNA-binding transcription factor activity
IF103_RS24000	COG5383	Protein conserved in bacteria
IF103_RS24005	COG0840	transmembrane signaling receptor activity
IF103_RS24015	COG0534	Mate efflux family protein
IF103_RS24030	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IF103_RS24035	COG0427	acetyl-CoA hydrolase
IF103_RS24065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IF103_RS24085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IF103_RS24095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IF103_RS24100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IF103_RS24110	COG1012	belongs to the aldehyde dehydrogenase family
IF103_RS24125	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IF103_RS24130	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IF103_RS24135	COG0747	negative chemotaxis
IF103_RS24140	COG2003	Belongs to the UPF0758 family
IF103_RS24145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IF103_RS24150	COG0756	dUTP diphosphatase activity
IF103_RS24155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IF103_RS24160	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IF103_RS24165	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IF103_RS24170	COG0708	Exodeoxyribonuclease III
IF103_RS24175	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IF103_RS24180	COG1561	YicC-like family, N-terminal region
IF103_RS24185	COG0194	GDP metabolic process
IF103_RS24195	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IF103_RS24200	COG0174	glutamine synthetase
IF103_RS24210	COG1758	RNA polymerase activity
IF103_RS24215	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IF103_RS24240	COG0848	biopolymer transport protein
IF103_RS24250	COG0583	DNA-binding transcription factor activity
IF103_RS24255	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IF103_RS24285	COG3161	chorismate lyase activity
IF103_RS24290	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IF103_RS24310	COG1253	flavin adenine dinucleotide binding
IF103_RS24315	COG0739	heme binding
IF103_RS24325	COG0704	Plays a role in the regulation of phosphate uptake
IF103_RS24330	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IF103_RS24335	COG0581	inorganic phosphate transmembrane transporter activity
IF103_RS24350	COG0477	Major facilitator Superfamily
IF103_RS24355	COG1607	acyl-coa hydrolase
IF103_RS24385	COG0583	DNA-binding transcription factor activity
IF103_RS24390	COG1027	Aspartate ammonia-lyase
IF103_RS24435	COG0511	ligase activity, forming carbon-carbon bonds
IF103_RS24435	COG5016	pyruvate
IF103_RS24440	COG0439	Biotin carboxylase
IF103_RS24445	COG0583	DNA-binding transcription factor activity
IF103_RS24455	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IF103_RS24460	COG3300	MHYT domain
IF103_RS24460	COG5001	Diguanylate cyclase
IF103_RS24465	COG0210	DNA helicase
IF103_RS24480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IF103_RS24480	COG4651	solute:proton antiporter activity
IF103_RS24485	COG1607	acyl-coa hydrolase
IF103_RS24490	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IF103_RS24500	COG0523	cobalamin synthesis protein
IF103_RS24520	COG1469	GTP cyclohydrolase I activity
IF103_RS24530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IF103_RS24535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IF103_RS24540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IF103_RS24545	COG1737	Transcriptional regulator
IF103_RS24565	COG4215	(ABC) transporter
IF103_RS24595	COG3436	PFAM IS66 Orf2 family protein
IF103_RS24640	COG3209	COG3209 Rhs family protein
IF103_RS24650	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IF103_RS24655	COG1349	DNA-binding transcription factor activity
IF103_RS24660	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IF103_RS24665	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IF103_RS24670	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IF103_RS24675	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IF103_RS24680	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IF103_RS24685	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IF103_RS24690	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IF103_RS24700	COG0356	it plays a direct role in the translocation of protons across the membrane
IF103_RS24705	COG3312	ion transport
IF103_RS24710	COG1475	DNA binding
IF103_RS24715	COG1192	Involved in chromosome partitioning
IF103_RS24720	COG0357	Ribosomal RNA small subunit methyltransferase G
IF103_RS24725	COG0445	tRNA wobble uridine modification
IF103_RS24730	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IF103_RS24735	COG0706	membrane insertase activity
IF103_RS24740	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IF103_RS24745	COG0594	ribonuclease P activity
IF103_RS24750	COG0230	Belongs to the bacterial ribosomal protein bL34 family