locus-tag	class	description
HG264_RS00070	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HG264_RS00075	ENOG4105CKK	Glycosyl transferase, family 2
HG264_RS00090	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HG264_RS00105	ENOG4105E0M	Sulfatase
HG264_RS00115	ENOG4105DHQ	Histidine kinase
HG264_RS00125	ENOG4105FQR	PH-inducible protein involved in stress response
HG264_RS00130	ENOG41080IJ	Diacylglycerol kinase
HG264_RS00135	ENOG4105E0M	Sulfatase
HG264_RS00145	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HG264_RS00150	ENOG4105D64	Mechanosensitive ion channel
HG264_RS00160	ENOG4107R9N	ABC transporter
HG264_RS00170	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
HG264_RS00175	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
HG264_RS00180	ENOG4108JQ9	ABC transporter
HG264_RS00195	ENOG4105DRR	Transcriptional regulator, GntR family
HG264_RS00205	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
HG264_RS00220	ENOG4107RT3	EamA-like transporter family
HG264_RS00255	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HG264_RS00260	ENOG4105CWN	amidohydrolase
HG264_RS00265	ENOG4105SKE	transcriptional Regulator LysR family
HG264_RS00270	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HG264_RS00275	ENOG4108CIP	transcriptional regulator
HG264_RS00280	ENOG4105DHU	Bile acid
HG264_RS00290	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HG264_RS00300	ENOG4107XKF	NMT1 THI5 Like Domain Protein
HG264_RS00305	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HG264_RS00315	ENOG4108YIQ	Alpha beta hydrolase
HG264_RS00330	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HG264_RS00340	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HG264_RS00345	ENOG4108R86	Transcriptional regulator
HG264_RS00360	ENOG4105UIB	(ABC) transporter
HG264_RS00365	ENOG4105C2J	ABC transporter
HG264_RS00375	ENOG4105C7W	Xanthine dehydrogenase
HG264_RS00390	ENOG4105VT2	5-hydroxyisourate hydrolase
HG264_RS00395	ENOG4107QUY	Guanine deaminase
HG264_RS00405	ENOG4105D2X	ABC transporter substrate-binding protein
HG264_RS00435	ENOG4105DJB	Major Facilitator Superfamily
HG264_RS00440	ENOG4105CBN	LysR family transcriptional regulator
HG264_RS00460	ENOG4105CHR	reductase
HG264_RS00495	ENOG4105C5X	domain protein
HG264_RS00500	ENOG4105DHQ	Histidine kinase
HG264_RS00505	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HG264_RS00510	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HG264_RS00520	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
HG264_RS00530	ENOG4108ZX6	Electron transport protein SCO1 SenC
HG264_RS00540	ENOG4105CGZ	zinc metallopeptidase
HG264_RS00555	ENOG4105CEY	Amp-dependent synthetase and ligase
HG264_RS00570	ENOG4105RWS	endonuclease I
HG264_RS00575	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HG264_RS00580	ENOG4105EQR	Transposase IS116 IS110 IS902
HG264_RS00590	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HG264_RS00595	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HG264_RS00605	ENOG4105C02	permease
HG264_RS00620	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HG264_RS00625	ENOG4105K89	arsenate reductase
HG264_RS00630	ENOG4107S2Z	UPF0761 membrane protein
HG264_RS00635	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HG264_RS00640	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
HG264_RS00655	ENOG4105J5J	Outer membrane porin
HG264_RS00665	ENOG41069P5	Protein slyX homolog
HG264_RS00680	ENOG4105C9M	aspartyl-trna synthetase
HG264_RS00690	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HG264_RS00695	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HG264_RS00700	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HG264_RS00705	ENOG4107YD3	Thioesterase
HG264_RS00710	ENOG4105E02	MotA TolQ exbB proton channel
HG264_RS00715	ENOG4105M8F	Biopolymer transport protein exbD tolR
HG264_RS00725	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HG264_RS00730	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HG264_RS00735	ENOG4105UFD	tol-pal system protein YbgF
HG264_RS00740	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HG264_RS00765	ENOG4108N8X	transition metal ion binding
HG264_RS00800	ENOG4105ERG	peptidase m48, ste24p
HG264_RS00805	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HG264_RS00815	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HG264_RS00820	ENOG4105RH4	Glycine cleavage system transcriptional repressor
HG264_RS00825	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HG264_RS00835	ENOG4105CY0	Metallo-Beta-Lactamase
HG264_RS00840	ENOG4105C8V	SAICAR synthetase
HG264_RS00930	ENOG4108YZA	Nitrogen regulatory protein pii
HG264_RS00935	ENOG4105PGM	cation diffusion facilitator family transporter
HG264_RS00940	ENOG4105J5J	Outer membrane porin
HG264_RS00945	ENOG4105W1Y	Transcriptional regulator
HG264_RS00970	ENOG4108IJF	Heavy metal efflux pump, CzcA
HG264_RS01010	ENOG4105E3B	Multicopper oxidase
HG264_RS01090	ENOG4105DFP	Integrase
HG264_RS01125	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HG264_RS01165	ENOG4108F3G	Type I restriction-modification system, R subunit
HG264_RS01175	ENOG4105EXC	Acyl-transferase
HG264_RS01185	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HG264_RS01190	ENOG4107Z6S	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HG264_RS01205	ENOG4107QHF	type ii secretion system protein e
HG264_RS01210	ENOG4105D7Q	type ii secretion system
HG264_RS01215	ENOG4108VAU	general secretion pathway protein G
HG264_RS01220	ENOG4105VWV	general secretion pathway protein h
HG264_RS01225	ENOG4105X5Z	General secretion pathway protein I
HG264_RS01230	ENOG4108WWZ	General secretion pathway protein J
HG264_RS01235	ENOG4108RTD	type II secretion system protein K
HG264_RS01240	ENOG4108ADH	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
HG264_RS01245	ENOG4105U1E	general secretion pathway protein M
HG264_RS01275	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HG264_RS01280	ENOG4105CN1	protease
HG264_RS01290	ENOG4105DFM	M18 family aminopeptidase
HG264_RS01295	ENOG4105D3G	Pseudouridine synthase
HG264_RS01300	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HG264_RS01305	ENOG4107QMS	site-determining protein
HG264_RS01310	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HG264_RS01315	ENOG4105D1S	lipid A biosynthesis
HG264_RS01355	ENOG4105ECQ	AraC Family Transcriptional Regulator
HG264_RS01360	ENOG4105C8Y	Acetylornithine aminotransferase
HG264_RS01365	ENOG4108T2Z	Arginine
HG264_RS01370	ENOG4105F4X	arginine
HG264_RS01375	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HG264_RS01380	ENOG4105CFH	Aspartokinase
HG264_RS01385	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HG264_RS01400	ENOG4105CJW	magnesium transporter
HG264_RS01405	ENOG4106AFN	Lyase and sodium transporter (By similarity)
HG264_RS01410	ENOG4107QSA	Oxaloacetate decarboxylase
HG264_RS01415	ENOG4105D9Q	decarboxylase (Beta subunit)
HG264_RS01430	ENOG4107HP6	Transcriptional regulator
HG264_RS01460	ENOG4105DTQ	mandelate racemase muconate lactonizing
HG264_RS01465	ENOG4105NN7	muconolactone delta-isomerase
HG264_RS01470	ENOG410626B	catechol 1,2-dioxygenase
HG264_RS01475	ENOG4105DKK	Benzoate
HG264_RS01490	ENOG4105F2Z	3-oxoadipate enol-lactonase
HG264_RS01500	ENOG4106825	Type iv pilus assembly
HG264_RS01510	ENOG4105M9M	anti-sigma28 factor FlgM
HG264_RS01525	ENOG4105BZU	Histidine kinase
HG264_RS01530	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HG264_RS01535	ENOG4108ZC9	flagellar basal-body rod protein flgc
HG264_RS01540	ENOG4105W00	Flagellar hook capping protein
HG264_RS01545	ENOG4105BZE	flagellar hook protein, FlgE
HG264_RS01550	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HG264_RS01555	ENOG4105CGA	flagellar basal-body rod protein FlgG
HG264_RS01565	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HG264_RS01570	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HG264_RS01575	ENOG4105E1Q	flagellar hook-associated protein
HG264_RS01580	ENOG4105DTJ	flagellar hook-associated protein
HG264_RS01585	ENOG4108Z6Z	Transcriptional regulator
HG264_RS01590	ENOG4105C59	p-type ATPase
HG264_RS01595	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HG264_RS01605	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
HG264_RS01610	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
HG264_RS01615	ENOG4105C7W	Xanthine dehydrogenase
HG264_RS01620	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
HG264_RS01625	ENOG4105FQ6	thiopurine methyltransferase
HG264_RS01635	ENOG4105ES5	Histidine kinase
HG264_RS01640	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HG264_RS01655	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HG264_RS01675	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HG264_RS01680	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HG264_RS01685	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HG264_RS01690	ENOG4105EUB	pirin domain protein
HG264_RS01705	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HG264_RS01710	ENOG4105YVS	arsR family transcriptional regulator
HG264_RS01715	ENOG4105CBP	Major Facilitator
HG264_RS01720	ENOG4105CH6	catalase
HG264_RS01735	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HG264_RS01755	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HG264_RS01760	ENOG41090A4	Pterin carbinolamine dehydratase
HG264_RS01765	ENOG4105QYV	Membrane
HG264_RS01770	ENOG4105C9Q	fumarate hydratase class II
HG264_RS01780	ENOG4105M85	Bola protein
HG264_RS01785	ENOG4105C72	UPF0176 protein
HG264_RS01815	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HG264_RS01820	ENOG4105D78	K07001 NTE family protein
HG264_RS01825	ENOG4105F8J	Adenylate Guanylate cyclase
HG264_RS01840	ENOG4108ZX5	transcriptional regulator
HG264_RS01850	ENOG410804D	Sensor Signal Transduction Histidine Kinase
HG264_RS01860	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HG264_RS01870	ENOG4105K9H	YciI-like protein
HG264_RS01875	ENOG4105DB7	PHP domain protein
HG264_RS01880	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HG264_RS01885	ENOG4105C31	Tryptophanyl-tRNA synthetase
HG264_RS01895	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HG264_RS01900	ENOG4105FE9	pseudouridine synthase
HG264_RS01905	ENOG4105BZU	Histidine kinase
HG264_RS01910	ENOG4105UBK	short-chain dehydrogenase reductase
HG264_RS01915	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HG264_RS01925	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HG264_RS01930	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
HG264_RS01935	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HG264_RS01940	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HG264_RS01945	ENOG4105CQC	Prephenate dehydratase
HG264_RS01950	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HG264_RS01955	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HG264_RS01960	ENOG4105CAT	Cytidine monophosphate kinase
HG264_RS01965	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HG264_RS01970	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HG264_RS01980	ENOG4105CFV	Tetratricopeptide repeat protein
HG264_RS01985	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HG264_RS01990	ENOG4108UQY	Iron-storage protein
HG264_RS01995	ENOG4105W53	bacterioferritin-associated ferredoxin
HG264_RS02005	ENOG4105CT4	transporter
HG264_RS02020	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HG264_RS02030	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HG264_RS02035	ENOG4105DBV	ornithine carbamoyltransferase
HG264_RS02040	ENOG4105M2J	Glutaredoxin
HG264_RS02045	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HG264_RS02050	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HG264_RS02055	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HG264_RS02075	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HG264_RS02080	ENOG4108Z66	YbaK ebsC protein
HG264_RS02085	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HG264_RS02090	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HG264_RS02100	ENOG4105BZU	Histidine kinase
HG264_RS02105	ENOG4105WH1	Two component transcriptional regulator luxr family
HG264_RS02120	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HG264_RS02140	ENOG4105C59	p-type ATPase
HG264_RS02155	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
HG264_RS02170	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HG264_RS02180	ENOG4105C8Q	Methyl-accepting chemotaxis
HG264_RS02185	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HG264_RS02190	ENOG4108K1J	Transporter DctQ
HG264_RS02195	ENOG4108KJ1	Trap dicarboxylate transporter, dctp subunit
HG264_RS02205	ENOG4105DHP	deoxycytidine triphosphate deaminase
HG264_RS02215	ENOG41068KF	Universal stress protein
HG264_RS02235	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HG264_RS02280	ENOG4105EWT	decarboxylase family
HG264_RS02285	ENOG4105H3G	oxidoreductase
HG264_RS02290	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HG264_RS02310	ENOG4105FEU	K -dependent Na -Ca exchanger
HG264_RS02320	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HG264_RS02335	ENOG4105EN6	Membrane
HG264_RS02370	ENOG4105CFP	Peptidase U32
HG264_RS02380	ENOG4105BZU	Histidine kinase
HG264_RS02385	ENOG4105BZU	Histidine kinase
HG264_RS02390	ENOG4105D74	hydrolase
HG264_RS02395	ENOG4108UKI	Enoyl-CoA hydratase
HG264_RS02415	ENOG4105ETU	transcriptional activator (TenA
HG264_RS02430	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
HG264_RS02435	ENOG4105DDY	UPF0142 protein ycaO
HG264_RS02440	ENOG4105D7A	ATP-binding protein
HG264_RS02470	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
HG264_RS02490	ENOG4105DEN	Luciferase family
HG264_RS02520	ENOG4105VEQ	Cold shock protein
HG264_RS02525	ENOG4105EQH	reductase
HG264_RS02535	ENOG4107EXC	regulatoR
HG264_RS02540	ENOG4105JJR	Histidine kinase
HG264_RS02565	ENOG4105DZ2	Transcriptional regulator
HG264_RS02570	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
HG264_RS02590	ENOG4107QI1	Mate efflux family protein
HG264_RS02595	ENOG4108BPE	-transporting atpase
HG264_RS02600	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
HG264_RS02625	ENOG4105CHM	Aminotransferase
HG264_RS02630	ENOG4105E0X	reductase
HG264_RS02640	ENOG4105BZU	Histidine kinase
HG264_RS02675	ENOG4107QPN	acyl-Coa dehydrogenase
HG264_RS02680	ENOG4105DA5	(ABC) transporter
HG264_RS02685	ENOG4105E3A	(ABC) transporter
HG264_RS02690	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HG264_RS02700	ENOG410903C	(LipO)protein
HG264_RS02705	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HG264_RS02715	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HG264_RS02720	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HG264_RS02765	ENOG4105F2V	VRR-NUC domain-containing protein
HG264_RS02775	ENOG4105D9P	serine threonine protein kinase
HG264_RS02820	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HG264_RS02825	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HG264_RS02875	ENOG4105CJP	fad dependent oxidoreductase
HG264_RS02880	ENOG4105HEI	LysR family (Transcriptional regulator
HG264_RS02885	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HG264_RS02910	ENOG4105CXN	decarboxylase
HG264_RS02920	ENOG4105NBK	UPF0345 protein
HG264_RS02930	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HG264_RS02940	ENOG4105BZN	citrate synthase
HG264_RS02945	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HG264_RS02950	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HG264_RS02955	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HG264_RS02960	ENOG4105E33	succinate dehydrogenase
HG264_RS02965	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HG264_RS02970	ENOG4105C7S	Dehydrogenase
HG264_RS02975	ENOG4107QN2	dihydrolipoyl dehydrogenase
HG264_RS02980	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HG264_RS02985	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HG264_RS02990	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HG264_RS03020	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HG264_RS03025	ENOG4107QM5	aconitate hydratase
HG264_RS03035	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HG264_RS03050	ENOG4105C01	Dihydroxy-acid dehydratase
HG264_RS03140	ENOG4105EA8	2-Nitropropane dioxygenase
HG264_RS03145	ENOG4105BZ1	(ABC) transporter
HG264_RS03155	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HG264_RS03160	ENOG4105GPY	SprT protein
HG264_RS03180	ENOG41069YE	inner membrane protein yohC
HG264_RS03185	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HG264_RS03195	ENOG4105K4H	Nlp p60 protein
HG264_RS03215	ENOG4105EPF	Outer membrane porin
HG264_RS03220	ENOG4105D3Y	Na H antiporter
HG264_RS03225	ENOG4105CDH	Citrulline--aspartate ligase
HG264_RS03250	ENOG4108ZZ3	UPF0260 protein
HG264_RS03255	ENOG410903C	(LipO)protein
HG264_RS03275	ENOG4105CSM	endonuclease III
HG264_RS03280	ENOG4105DZB	Electron transport complex
HG264_RS03285	ENOG4108UQQ	Electron transport complex
HG264_RS03290	ENOG4105D6A	Electron transport complex
HG264_RS03300	ENOG4108R3D	Electron transport complex
HG264_RS03305	ENOG4105DGN	Electron transport complex
HG264_RS03310	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HG264_RS03360	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HG264_RS03405	ENOG4107R88	Chemotaxis protein (CheV)
HG264_RS03410	ENOG4105D25	secreted protein
HG264_RS03415	ENOG4108UNF	response regulator
HG264_RS03420	ENOG4105C1J	atp-dependent rna helicase
HG264_RS03430	ENOG41090ED	Protein with unknown function (DUF469)
HG264_RS03435	ENOG4108V0P	LemA family
HG264_RS03440	ENOG4105HA9	of methanol dehydrogenase type
HG264_RS03460	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HG264_RS03485	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HG264_RS03495	ENOG4108MAJ	Membrane
HG264_RS03500	ENOG4105C8Q	Methyl-accepting chemotaxis
HG264_RS03520	ENOG4105D6Z	AFG1 family ATPase
HG264_RS03535	ENOG4105DZG	Dehydrogenase
HG264_RS03545	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
HG264_RS03550	ENOG4105GRZ	Ycii-related protein
HG264_RS03555	ENOG4108SQ4	Glyoxalase Bleomycin resistance protein (Dioxygenase
HG264_RS03560	ENOG4105CHP	RNA polymerase
HG264_RS03565	ENOG4105CHM	Aminotransferase
HG264_RS03580	ENOG4108JPW	Aminotransferase
HG264_RS03585	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HG264_RS03590	ENOG4105C26	Dehydrogenase
HG264_RS03595	ENOG4105C87	Aminotransferase class I and II
HG264_RS03615	ENOG4105C2C	drug resistance transporter, Bcr CflA
HG264_RS03620	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
HG264_RS03630	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HG264_RS03635	ENOG4105CEY	Amp-dependent synthetase and ligase
HG264_RS03640	ENOG4105BZU	Histidine kinase
HG264_RS03650	ENOG4107RNH	Outer membrane receptor FepA
HG264_RS03655	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HG264_RS03695	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
HG264_RS03700	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
HG264_RS03710	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HG264_RS03725	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HG264_RS03735	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
HG264_RS03745	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HG264_RS03750	ENOG4105DP0	ferredoxin-NADP reductase
HG264_RS03755	ENOG4105DUM	transcriptional regulator, lysR family
HG264_RS03760	ENOG4107MBR	17 kDa surface antigen
HG264_RS03765	ENOG4105BZU	Histidine kinase
HG264_RS03770	ENOG4108MP6	LysR family Transcriptional regulator
HG264_RS03775	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HG264_RS03780	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HG264_RS03785	ENOG4105F2W	methyltransferase
HG264_RS03790	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HG264_RS03795	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HG264_RS03810	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HG264_RS03815	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HG264_RS03820	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HG264_RS03825	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HG264_RS03835	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HG264_RS03845	ENOG4105E96	Colicin v production protein
HG264_RS03850	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HG264_RS03855	ENOG4105C28	cystathionine
HG264_RS03860	ENOG4105KQC	Competence protein
HG264_RS03875	ENOG4105VNG	YcgL domain-containing protein
HG264_RS03885	ENOG4105VRT	cytoplasmic protein
HG264_RS03890	ENOG4105CEY	Amp-dependent synthetase and ligase
HG264_RS03900	ENOG4105CM6	amino acid regulated cytosolic protein
HG264_RS03905	ENOG4106K28	UPF0283 membrane protein
HG264_RS03920	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
HG264_RS03925	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
HG264_RS03935	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HG264_RS03940	ENOG4105CK7	Sodium proline symporter
HG264_RS03945	ENOG4105CUG	Oligopeptidase b
HG264_RS03960	ENOG4105VEQ	Cold shock protein
HG264_RS03965	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
HG264_RS03970	ENOG4105C6T	cysteine synthase
HG264_RS03980	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HG264_RS03990	ENOG4107E2E	PKHD-type hydroxylase
HG264_RS04000	ENOG4108IU3	tonb-dependent siderophore receptor
HG264_RS04010	ENOG4109015	Biopolymer transport protein exbD tolR
HG264_RS04025	ENOG4108Z7G	MaoC domain protein dehydratase
HG264_RS04030	ENOG4105CEY	Amp-dependent synthetase and ligase
HG264_RS04035	ENOG4105CEY	Amp-dependent synthetase and ligase
HG264_RS04040	ENOG4105CQ7	ATP-dependent helicase
HG264_RS04070	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HG264_RS04075	ENOG4105CR8	Transcriptional regulator
HG264_RS04090	ENOG4105CGF	Aromatic amino acid aminotransferase
HG264_RS04095	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HG264_RS04175	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HG264_RS04245	ENOG4106FAK	Endodeoxyribonuclease RusA
HG264_RS04265	ENOG4105KUS	lysozyme
HG264_RS04280	ENOG4105FKG	DNA packaging protein
HG264_RS04285	ENOG4105UZW	Tail fiber assembly protein
HG264_RS04300	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HG264_RS04340	ENOG4108NYK	Tape measure protein
HG264_RS04375	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HG264_RS04390	ENOG4105C22	threonyL-tRNA synthetase
HG264_RS04395	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HG264_RS04415	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HG264_RS04420	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HG264_RS04445	ENOG4105EXC	Acyl-transferase
HG264_RS04450	ENOG4108UWD	Iron-storage protein
HG264_RS04460	ENOG4107IFA	Lipase (EC 3.1.1.3)
HG264_RS04470	ENOG4105EBR	Carboxylesterase
HG264_RS04510	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HG264_RS04515	ENOG4105CHR	reductase
HG264_RS04555	ENOG4105CS2	ec 3.2.1.21
HG264_RS04560	ENOG4105BZ1	(ABC) transporter
HG264_RS04595	ENOG4105DQ4	alcohol dehydrogenase
HG264_RS04600	ENOG4107RH8	nuclease SbcCD subunit D
HG264_RS04620	ENOG4107QN1	sodium solute
HG264_RS04640	ENOG4105DY8	decarboxylase
HG264_RS04670	ENOG4105EYM	Major Facilitator superfamily
HG264_RS04675	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HG264_RS04690	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HG264_RS04695	ENOG4105WH1	Two component transcriptional regulator luxr family
HG264_RS04700	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HG264_RS04760	ENOG4105WH1	Two component transcriptional regulator luxr family
HG264_RS04765	ENOG4105BZU	Histidine kinase
HG264_RS04780	ENOG4105FAE	von Willebrand factor, type A
HG264_RS04785	ENOG4105DSQ	Nitric oxide reductase
HG264_RS04790	ENOG4108VKQ	nitriC oxide reductase
HG264_RS04815	ENOG4105CIG	ABC transporter
HG264_RS04820	ENOG4108T0W	nitrous oxide maturation protein NosY
HG264_RS04835	ENOG4105WD1	Membrane
HG264_RS04840	ENOG4107RU9	Transcriptional regulator, Crp Fnr family
HG264_RS04850	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
HG264_RS04860	ENOG4108VKQ	nitriC oxide reductase
HG264_RS04885	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HG264_RS04900	ENOG4105EMK	carboxylate amino acid amine transporter
HG264_RS04905	ENOG4107U9T	Pfam:Ribonuclease_BN
HG264_RS04920	ENOG4105DC8	reductase
HG264_RS04925	ENOG4105EN6	Membrane
HG264_RS04945	ENOG4105WKW	Pfam:DUF1458
HG264_RS04950	ENOG41080XP	Cbs domain
HG264_RS04955	ENOG4105DSB	aldose 1-epimerase
HG264_RS04980	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HG264_RS04985	ENOG4105MA0	exported protein
HG264_RS04990	ENOG4105CFU	surface antigen
HG264_RS04995	ENOG4105CGK	Exodeoxyribonuclease III
HG264_RS05000	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HG264_RS05005	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HG264_RS05010	ENOG4105VEQ	Cold shock protein
HG264_RS05025	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HG264_RS05030	ENOG41075W9	High frequency lysogenization protein HflD homolog
HG264_RS05040	ENOG4107QTF	adenylosuccinate lyase
HG264_RS05045	ENOG4105EZE	Cupin 4 family protein
HG264_RS05060	ENOG4107RET	Isocitrate lyase
HG264_RS05070	ENOG4105CDV	Ompa motb domain protein
HG264_RS05105	ENOG4108R4R	Iron-regulated virulence regulatory protein
HG264_RS05110	ENOG4105D05	Receptor
HG264_RS05135	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HG264_RS05145	ENOG4108Z4V	iron-sulfur cluster assembly
HG264_RS05150	ENOG4105C9B	Cysteine desulfurase
HG264_RS05160	ENOG4105C3K	feS assembly ATPase SufC
HG264_RS05170	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HG264_RS05180	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HG264_RS05185	ENOG4105W8H	transhydrogenase (subunit alpha
HG264_RS05190	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HG264_RS05210	ENOG4105C8N	cysteinyl-tRNA synthetase
HG264_RS05215	ENOG4105CX6	glutaminyL-tRNA synthetase
HG264_RS05220	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HG264_RS05225	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HG264_RS05230	ENOG4105C10	Electron transfer flavoprotein
HG264_RS05235	ENOG4105BZJ	Electron transfer flavoprotein
HG264_RS05240	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HG264_RS05245	ENOG4105PI0	Ferredoxin
HG264_RS05265	ENOG4108YZN	class I peptide chain release factor
HG264_RS05280	ENOG4105CH6	catalase
HG264_RS05290	ENOG4105DSF	transport protein
HG264_RS05305	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HG264_RS05310	ENOG4105BZS	acriflavin resistance protein
HG264_RS05320	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
HG264_RS05325	ENOG4108MG3	formate dehydrogenase
HG264_RS05330	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HG264_RS05345	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HG264_RS05370	ENOG4105EEQ	Na H antiporter
HG264_RS05385	ENOG4105PGM	cation diffusion facilitator family transporter
HG264_RS05390	ENOG4108XDN	Transcriptional regulator
HG264_RS05395	ENOG4105BZU	Histidine kinase
HG264_RS05400	ENOG4107SDU	Methyl-accepting chemotaxis
HG264_RS05415	ENOG4108XDN	Transcriptional regulator
HG264_RS05420	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HG264_RS05425	ENOG4108RAV	Conserved protein
HG264_RS05430	ENOG4105CQZ	Histidine kinase
HG264_RS05435	ENOG4105BZU	Histidine kinase
HG264_RS05445	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
HG264_RS05450	ENOG4105FUA	antagonist
HG264_RS05455	ENOG4107MMM	Anti-sigma-factor antagonist
HG264_RS05465	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HG264_RS05485	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HG264_RS05500	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HG264_RS05540	ENOG4105C4R	Atp-dependent dna helicase
HG264_RS05555	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HG264_RS05575	ENOG4108MN8	Membrane
HG264_RS05580	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
HG264_RS05585	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HG264_RS05595	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
HG264_RS05600	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HG264_RS05605	ENOG4107RZC	phospholipase d
HG264_RS05620	ENOG4108ZZF	transport protein (ExbD)
HG264_RS05625	ENOG4105CWK	Biopolymer transport protein, ExbB
HG264_RS05640	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HG264_RS05655	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
HG264_RS05665	ENOG4105D22	carbon starvation protein
HG264_RS05670	ENOG4105QNF	Outer membrane lipoprotein
HG264_RS05675	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HG264_RS05680	ENOG4105D7N	magnesium and cobalt transport protein CorA
HG264_RS05690	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HG264_RS05695	ENOG4105WMR	Protein CrcB homolog
HG264_RS05700	ENOG4105D1H	recombination factor protein RarA
HG264_RS05705	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HG264_RS05710	ENOG4105CNU	cell division protein FtsK
HG264_RS05715	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HG264_RS05720	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
HG264_RS05725	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HG264_RS05745	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HG264_RS05755	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
HG264_RS05765	ENOG4107QIJ	Aconitate hydratase 2
HG264_RS05770	ENOG4105SUV	lipoprotein YgdR
HG264_RS05790	ENOG41062WK	cellular response to acidity
HG264_RS05825	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HG264_RS05830	ENOG4105CDY	transcriptional regulatory protein
HG264_RS05840	ENOG4105F8C	transglutaminase domain-containing protein
HG264_RS05850	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HG264_RS05865	ENOG4105NXH	GreA GreB family elongation factor
HG264_RS05870	ENOG4105CGY	Dna recombination protein
HG264_RS05900	ENOG4105EBR	Carboxylesterase
HG264_RS05915	ENOG4105F8V	Hydrolase, tatD family
HG264_RS05925	ENOG4107QRG	dna polymerase iii
HG264_RS05930	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HG264_RS05935	ENOG4105HHA	aminodeoxychorismate lyase
HG264_RS05940	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
HG264_RS05945	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HG264_RS05950	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HG264_RS05955	ENOG4105CHR	reductase
HG264_RS05960	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HG264_RS05965	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HG264_RS05970	ENOG4105VGS	50s ribosomal protein l32
HG264_RS05975	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HG264_RS05980	ENOG4108UHJ	MAF-like protein
HG264_RS05985	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HG264_RS05990	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HG264_RS05995	ENOG4105EI2	Pseudouridine synthase
HG264_RS06000	ENOG4105C03	ribonuclease
HG264_RS06005	ENOG4105D4A	Cell wall formation (By similarity)
HG264_RS06015	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HG264_RS06020	ENOG4105W49	UPF0434 protein
HG264_RS06025	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HG264_RS06030	ENOG4109015	Biopolymer transport protein exbD tolR
HG264_RS06040	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HG264_RS06050	ENOG4105EW9	transcriptional regulator AsnC family
HG264_RS06055	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HG264_RS06065	ENOG4108K88	Membrane
HG264_RS06070	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HG264_RS06090	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HG264_RS06095	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
HG264_RS06110	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
HG264_RS06115	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HG264_RS06125	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HG264_RS06130	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HG264_RS06135	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HG264_RS06145	ENOG4108JA2	transcriptioN-repair coupling factor
HG264_RS06155	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
HG264_RS06195	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HG264_RS06210	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HG264_RS06215	ENOG41081QV	Universal stress protein
HG264_RS06220	ENOG4105C5H	ABC transporter
HG264_RS06225	ENOG4107SC1	transglycosylase
HG264_RS06235	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
HG264_RS06240	ENOG4105C3R	Methionine synthase
HG264_RS06255	ENOG4107QI1	Mate efflux family protein
HG264_RS06265	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HG264_RS06280	ENOG4105ERU	peptidase
HG264_RS06295	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HG264_RS06305	ENOG4105E09	nadh pyrophosphatase
HG264_RS06315	ENOG4105E39	Enoyl-CoA hydratase
HG264_RS06320	ENOG4107RZZ	dna polymerase iii epsilon subunit
HG264_RS06325	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HG264_RS06335	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HG264_RS06340	ENOG4105E9H	Lytic Murein transglycosylase
HG264_RS06350	ENOG4105E43	Extracellular solute-binding protein, family 5
HG264_RS06355	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
HG264_RS06360	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
HG264_RS06365	ENOG4108JQ5	ABC transporter
HG264_RS06370	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HG264_RS06375	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HG264_RS06380	ENOG4105K70	DNA-binding protein
HG264_RS06385	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HG264_RS06390	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HG264_RS06395	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HG264_RS06400	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HG264_RS06405	ENOG4105BZU	Histidine kinase
HG264_RS06410	ENOG4108VAU	general secretion pathway protein G
HG264_RS06430	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HG264_RS06435	ENOG4105C7F	AcnD-accessory protein PrpF
HG264_RS06440	ENOG4108I0Z	Aconitate hydratase
HG264_RS06445	ENOG4105BZN	citrate synthase
HG264_RS06450	ENOG4105CR4	methylisocitrate lyase
HG264_RS06455	ENOG4105DRR	Transcriptional regulator, GntR family
HG264_RS06465	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HG264_RS06475	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
HG264_RS06485	ENOG4107R11	Transcriptional regulator
HG264_RS06495	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HG264_RS06500	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HG264_RS06510	ENOG4105CY2	Citrate transporter
HG264_RS06520	ENOG4108PXI	ErfK YbiS YcfS YnhG
HG264_RS06530	ENOG4108UJV	acyl-CoA thioesterase i
HG264_RS06535	ENOG4108I0Y	(ABC) transporter
HG264_RS06540	ENOG4105CV6	ABC transporter, permease
HG264_RS06545	ENOG4108RRZ	Transcription elongation factor GreB
HG264_RS06550	ENOG4105CHF	Glutathione S-transferase
HG264_RS06560	ENOG4105F8V	Hydrolase, tatD family
HG264_RS06570	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HG264_RS06575	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
HG264_RS06580	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HG264_RS06590	ENOG4105C7I	Dehydrogenase
HG264_RS06595	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HG264_RS06610	ENOG4107QVM	von Willebrand factor, type A
HG264_RS06625	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
HG264_RS06640	ENOG4105CD8	aminopeptidase N
HG264_RS06650	ENOG4105VUT	cytoplasmic protein
HG264_RS06655	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
HG264_RS06660	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HG264_RS06680	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HG264_RS06700	ENOG4108IEG	Formate dehydrogenase Alpha subunit
HG264_RS06735	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
HG264_RS06745	ENOG4105CT3	Monooxygenase
HG264_RS06765	ENOG4107RGD	Major Facilitator superfamily
HG264_RS06770	ENOG4105C1G	acyl-Coa dehydrogenase
HG264_RS06795	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
HG264_RS06800	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HG264_RS06805	ENOG4105C8Q	Methyl-accepting chemotaxis
HG264_RS06815	ENOG4105EKE	dihydroorotase
HG264_RS06820	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
HG264_RS06825	ENOG4105H1G	trap transporter solute receptor taxi family
HG264_RS06840	ENOG4105E1F	short-chain dehydrogenase reductase
HG264_RS06855	ENOG4108JJ7	ABC transporter
HG264_RS06865	ENOG4105BZS	acriflavin resistance protein
HG264_RS06880	ENOG4105E33	succinate dehydrogenase
HG264_RS06885	ENOG4108J5G	6-phosphogluconate dehydrogenase
HG264_RS06890	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HG264_RS06900	ENOG4105CMR	udp-glucose 4-epimerase
HG264_RS06905	ENOG4107QKV	phosphomannomutase
HG264_RS06915	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HG264_RS06920	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HG264_RS06930	ENOG41090RK	glycosyl transferase
HG264_RS06960	ENOG4105ESV	Glycosyl transferase, family 4
HG264_RS06985	ENOG4107QQG	Dehydrogenase
HG264_RS07025	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HG264_RS07035	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
HG264_RS07045	ENOG4105CY0	Metallo-Beta-Lactamase
HG264_RS07050	ENOG4105KJF	protein tyrosine phosphatase
HG264_RS07065	ENOG4105DAY	polysaccharide export protein
HG264_RS07080	ENOG4105E3R	(LipO)protein
HG264_RS07095	ENOG4105C1J	atp-dependent rna helicase
HG264_RS07100	ENOG4105D25	secreted protein
HG264_RS07115	ENOG4105D25	secreted protein
HG264_RS07125	ENOG4105D25	secreted protein
HG264_RS07135	ENOG4108ZX5	transcriptional regulator
HG264_RS07145	ENOG4105C1G	acyl-Coa dehydrogenase
HG264_RS07150	ENOG4105CHR	reductase
HG264_RS07160	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HG264_RS07170	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HG264_RS07175	ENOG4105CF1	Alkylated DNA repair protein
HG264_RS07180	ENOG4105CSU	acyl-Coa dehydrogenase
HG264_RS07185	ENOG4105CHU	acetyl-coa acetyltransferase
HG264_RS07210	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
HG264_RS07225	ENOG4105C8P	)-transporter
HG264_RS07235	ENOG4108M1T	Cytochrome c-type biogenesis protein
HG264_RS07240	ENOG4105KWW	Biogenesis protein
HG264_RS07245	ENOG4107QX9	Thiol disulfide interChange protein
HG264_RS07250	ENOG4105DA4	cytochrome c-type biogenesis protein
HG264_RS07260	ENOG41067VX	Heme exporter protein
HG264_RS07265	ENOG41060IM	Heme exporter protein
HG264_RS07270	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HG264_RS07275	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
HG264_RS07285	ENOG4105D00	flagellar biosynthetic protein flhB
HG264_RS07295	ENOG4108V3W	Chemotaxis protein, CheW
HG264_RS07305	ENOG4107QJE	Chromosome Partitioning Protein
HG264_RS07310	ENOG4106VK6	Flagellar motor protein
HG264_RS07315	ENOG4105E14	MotA TolQ exbB proton channel
HG264_RS07320	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HG264_RS07330	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HG264_RS07335	ENOG4108VYJ	response regulator receiver protein
HG264_RS07340	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HG264_RS07350	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HG264_RS07355	ENOG4105D7B	Flagellar biosynthesis protein flha
HG264_RS07365	ENOG4105BZU	Histidine kinase
HG264_RS07370	ENOG4105DEN	Luciferase family
HG264_RS07410	ENOG4105EPF	Outer membrane porin
HG264_RS07415	ENOG4108SY4	MarR family Transcriptional regulator
HG264_RS07420	ENOG4105C1G	acyl-Coa dehydrogenase
HG264_RS07425	ENOG4108IPT	Naphthoate synthase
HG264_RS07435	ENOG4105CEY	Amp-dependent synthetase and ligase
HG264_RS07440	ENOG4105E39	Enoyl-CoA hydratase
HG264_RS07445	ENOG4105D4P	Coproporphyrinogen iii oxidase
HG264_RS07455	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HG264_RS07460	ENOG4105E0C	molybdate abc transporter
HG264_RS07465	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HG264_RS07475	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HG264_RS07480	ENOG4108ZAF	Molybdopterin
HG264_RS07485	ENOG4105M00	molybdopterin converting factor, subunit 1
HG264_RS07495	ENOG4105D3R	alkyl hydroperoxide reductase
HG264_RS07500	ENOG4108JU3	Alkyl hydroperoxide reductase
HG264_RS07505	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HG264_RS07545	ENOG4105CJB	Exodeoxyribonuclease I
HG264_RS07560	ENOG4105Q9Y	Universal stress protein
HG264_RS07565	ENOG4108UHU	Aldolase
HG264_RS07575	ENOG4105C01	Dihydroxy-acid dehydratase
HG264_RS07580	ENOG4105CA9	Pyruvate kinase
HG264_RS07585	ENOG4107GFK	fumarate
HG264_RS07590	ENOG4105BZU	Histidine kinase
HG264_RS07600	ENOG4105E39	Enoyl-CoA hydratase
HG264_RS07630	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
HG264_RS07635	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HG264_RS07640	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HG264_RS07645	ENOG4105BZU	Histidine kinase
HG264_RS07655	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HG264_RS07660	ENOG4108K5P	(LipO)protein
HG264_RS07670	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HG264_RS07675	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HG264_RS07680	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HG264_RS07715	ENOG4105BZU	Histidine kinase
HG264_RS07720	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HG264_RS07725	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HG264_RS07730	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HG264_RS07735	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HG264_RS07750	ENOG4105D74	hydrolase
HG264_RS07755	ENOG4105EX9	Membrane
HG264_RS07760	ENOG410649J	Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity)
HG264_RS07765	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HG264_RS07775	ENOG4108JPW	Aminotransferase
HG264_RS07780	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
HG264_RS07785	ENOG4105EV8	ectoine hydroxylase
HG264_RS07790	ENOG4105CZK	Aspartate kinase
HG264_RS07805	ENOG4105C31	Tryptophanyl-tRNA synthetase
HG264_RS07815	ENOG4105D00	flagellar biosynthetic protein flhB
HG264_RS07820	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HG264_RS07825	ENOG4105VS8	Flagellar biosynthetic protein fliq
HG264_RS07830	ENOG4105CN7	Flagellar biosynthetic protein FliP
HG264_RS07835	ENOG4105VTB	flagellar biosynthesis protein fliO
HG264_RS07840	ENOG4105DD5	Flagellar motor switch protein
HG264_RS07845	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HG264_RS07865	ENOG4108PYU	two-component system response regulator
HG264_RS07880	ENOG4108JIR	Flagellum-specific ATP synthase
HG264_RS07890	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HG264_RS07895	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HG264_RS07915	ENOG4105BZU	Histidine kinase
HG264_RS07930	ENOG4105MQ3	flagellar protein FliS
HG264_RS07940	ENOG4105DTS	flagellar hook-associated
HG264_RS07990	ENOG4108YI3	3-hydroxyacyl-CoA-acyl carrier protein transferase
HG264_RS08005	ENOG4107T9Q	phosphonate abc transporter
HG264_RS08030	ENOG4105CP9	extracellular ligand-binding receptor
HG264_RS08035	ENOG4105C32	Amino acid ABC transporter (Permease)
HG264_RS08040	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HG264_RS08045	ENOG4105C0Z	ABC transporter
HG264_RS08050	ENOG4108IV0	ABC, transporter
HG264_RS08060	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HG264_RS08100	ENOG4108WC9	type VI secretion system effector, hcp1 family
HG264_RS08105	ENOG4105KJM	monovalent cation h antiporter subunit g
HG264_RS08115	ENOG4105SC1	monovalent cation H antiporter subunit E
HG264_RS08120	ENOG4107R4Z	monovalent cation h antiporter subunit d
HG264_RS08125	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HG264_RS08130	ENOG4105D65	subunit l
HG264_RS08140	ENOG41080TA	Multiple resistance and ph regulation protein f
HG264_RS08145	ENOG4105SC1	monovalent cation H antiporter subunit E
HG264_RS08150	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HG264_RS08155	ENOG4105MKQ	Monovalent cation H antiporter subunit C
HG264_RS08160	ENOG4105D65	subunit l
HG264_RS08190	ENOG4108RAV	Conserved protein
HG264_RS08200	ENOG41090KI	Outer membrane porin
HG264_RS08225	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HG264_RS08230	ENOG4105E7A	Glutamine amidotransferase
HG264_RS08235	ENOG4105W4M	Transport-associated protein
HG264_RS08245	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HG264_RS08250	ENOG4105CQ7	ATP-dependent helicase
HG264_RS08260	ENOG41076HS	cation diffusion facilitator family transporter
HG264_RS08265	ENOG4108XM1	transcriptional regulator AsnC family
HG264_RS08275	ENOG4105CSU	acyl-Coa dehydrogenase
HG264_RS08280	ENOG4108R99	pseudouridine synthase
HG264_RS08290	ENOG4105IJY	hydroxylase
HG264_RS08310	ENOG41087PP	glycosyltransferase MGT family
HG264_RS08315	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
HG264_RS08320	ENOG4108UK3	Polyprenyl synthetase
HG264_RS08330	ENOG4105DWF	phosphomethylpyrimidine kinase
HG264_RS08335	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HG264_RS08340	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HG264_RS08365	ENOG4105C9A	Phoh family
HG264_RS08370	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HG264_RS08375	ENOG4108JU5	Magnesium and cobalt efflux protein
HG264_RS08380	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HG264_RS08390	ENOG4105C8T	Leucyl-tRNA synthetase
HG264_RS08410	ENOG4105CHH	sulfate transporter
HG264_RS08415	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HG264_RS08430	ENOG4105CVE	Lytic murein transglycosylase
HG264_RS08435	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HG264_RS08440	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HG264_RS08445	ENOG41084BA	UPF0250 protein
HG264_RS08450	ENOG4105DZ1	carboxypeptidase
HG264_RS08460	ENOG4105CVE	Lytic murein transglycosylase
HG264_RS08465	ENOG4105CNI	cell division protein FtsW
HG264_RS08470	ENOG4105CJN	penicillin-binding protein
HG264_RS08475	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HG264_RS08485	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HG264_RS08490	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HG264_RS08495	ENOG4108RB4	3-methyladenine DNA glycosylase
HG264_RS08500	ENOG4108KF1	Membrane
HG264_RS08520	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HG264_RS08525	ENOG4105DFU	Cell wall formation (By similarity)
HG264_RS08530	ENOG4105CTQ	phosphohexokinase
HG264_RS08535	ENOG4105F0N	pyrophosphate phospho-hydrolase
HG264_RS08540	ENOG4106371	Methyltransferase
HG264_RS08545	ENOG4107R73	Mate efflux family protein
HG264_RS08550	ENOG4108ZJT	translation initiation factor, Sui1
HG264_RS08555	ENOG4105PTV	Nudix Hydrolase
HG264_RS08565	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HG264_RS08570	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HG264_RS08575	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HG264_RS08580	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HG264_RS08595	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HG264_RS08600	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HG264_RS08610	ENOG4105C12	Phosphoribosylglycinamide synthetase
HG264_RS08615	ENOG4105BZU	Histidine kinase
HG264_RS08620	ENOG4105CCT	upf0313 protein
HG264_RS08625	ENOG4105CDU	Replicative dna helicase
HG264_RS08630	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HG264_RS08640	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HG264_RS08650	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HG264_RS08655	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HG264_RS08670	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HG264_RS08680	ENOG4105EPW	hflc protein
HG264_RS08685	ENOG4107QJR	hflk protein
HG264_RS08690	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HG264_RS08695	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HG264_RS08700	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HG264_RS08705	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HG264_RS08710	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HG264_RS08715	ENOG4105K8N	protein family UPF0079, ATPase
HG264_RS08720	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HG264_RS08725	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HG264_RS08730	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HG264_RS08735	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HG264_RS08740	ENOG4105ER2	Ompa motb domain protein
HG264_RS08745	ENOG4107RD7	Flagellar Motor Protein, MotA
HG264_RS08750	ENOG4105KHC	sulfurtransferase
HG264_RS08755	ENOG4105DJ4	phosphatidylserine decarboxylase
HG264_RS08760	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
HG264_RS08765	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HG264_RS08770	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HG264_RS08795	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HG264_RS08805	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HG264_RS08810	ENOG4105IJJ	transcriptional regulator, crp fnr family
HG264_RS08820	ENOG4105CT3	Monooxygenase
HG264_RS08825	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HG264_RS08835	ENOG41087AY	ADP-Ribose pyrophosphatase
HG264_RS08845	ENOG4105DFG	type I secretion outer membrane protein
HG264_RS08850	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HG264_RS08855	ENOG41087SS	fad dependent oxidoreductase
HG264_RS08860	ENOG4107SET	aldo keto reductase
HG264_RS08875	ENOG4105BZ1	(ABC) transporter
HG264_RS08890	ENOG4105K64	Glycosyl transferase, family 2
HG264_RS08900	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HG264_RS08905	ENOG4105CPK	Glycosyl transferase (Group 1
HG264_RS08925	ENOG4107543	(lipo)polysaccharide
HG264_RS08930	ENOG4107RJ7	Glycosyl transferase (Group 1
HG264_RS08935	ENOG4105D16	lipopolysaccharide heptosyltransferase i
HG264_RS08940	ENOG4105XA0	heptosyltransferase ii
HG264_RS08945	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HG264_RS08950	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HG264_RS08955	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HG264_RS08960	ENOG4107QSN	dihydrolipoamide acetyltransferase
HG264_RS08970	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HG264_RS08975	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HG264_RS08980	ENOG4105C34	Pseudouridine synthase
HG264_RS08985	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HG264_RS08995	ENOG4107TUY	Histidine kinase
HG264_RS09000	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HG264_RS09005	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HG264_RS09010	ENOG4105DWT	malate dehydrogenase (quinone)
HG264_RS09025	ENOG4105EXC	Acyl-transferase
HG264_RS09035	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HG264_RS09040	ENOG4105BZU	Histidine kinase
HG264_RS09045	ENOG4105C5H	ABC transporter
HG264_RS09050	ENOG4105D82	Glutamate dehydrogenase
HG264_RS09060	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HG264_RS09065	ENOG4105CSR	polyphosphate kinase 2
HG264_RS09070	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HG264_RS09075	ENOG4105DAN	ATP-dependent protease
HG264_RS09080	ENOG4105EXQ	uroporphyrinogen iii synthase hem4
HG264_RS09115	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HG264_RS09120	ENOG4105CPQ	Dehydrogenase
HG264_RS09165	ENOG4105KHS	type IV fimbrial pilin protein
HG264_RS09170	ENOG4107QHF	type ii secretion system protein e
HG264_RS09180	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
HG264_RS09185	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HG264_RS09195	ENOG4108UB3	Thiamine monophosphate
HG264_RS09200	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HG264_RS09205	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HG264_RS09210	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HG264_RS09215	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HG264_RS09220	ENOG4105DTN	riboflavin biosynthesis protein ribF
HG264_RS09225	ENOG4105CJR	Integral membrane protein (MviN
HG264_RS09230	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HG264_RS09235	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HG264_RS09245	ENOG4105K46	50S ribosomal protein l27
HG264_RS09250	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HG264_RS09255	ENOG4105EAH	synthase
HG264_RS09260	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HG264_RS09265	ENOG4105C7N	Xanthine uracil vitamin C permease
HG264_RS09330	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HG264_RS09380	ENOG4105X0D	Fimbrial protein
HG264_RS09450	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HG264_RS09460	ENOG4105DR5	peptidase
HG264_RS09475	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HG264_RS09480	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HG264_RS09485	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HG264_RS09490	ENOG4105CPF	Cell wall formation (By similarity)
HG264_RS09500	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HG264_RS09505	ENOG4105CNI	cell division protein FtsW
HG264_RS09510	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HG264_RS09515	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HG264_RS09520	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HG264_RS09525	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HG264_RS09530	ENOG4105CJN	penicillin-binding protein
HG264_RS09540	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HG264_RS09555	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HG264_RS09560	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
HG264_RS09565	ENOG41082RQ	UPF0102 protein
HG264_RS09575	ENOG4105W4M	Transport-associated protein
HG264_RS09580	ENOG4105KB2	stringent starvation protein b
HG264_RS09585	ENOG4107MKT	Stringent starvation protein a
HG264_RS09590	ENOG4105EIX	cytochrome c1
HG264_RS09595	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HG264_RS09600	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HG264_RS09605	ENOG4108UJD	30S ribosomal protein S9
HG264_RS09610	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HG264_RS09615	ENOG4105CPC	Aldo Keto reductase
HG264_RS09620	ENOG4105D6Z	AFG1 family ATPase
HG264_RS09640	ENOG4105DHJ	ABC, transporter
HG264_RS09655	ENOG4105EXC	Acyl-transferase
HG264_RS09665	ENOG4105DGA	Diaminopimelate dehydrogenase
HG264_RS09670	ENOG4107T2D	Phosphoribosylaminoimidazolesuccinocarboxamide synthase
HG264_RS09675	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HG264_RS09680	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HG264_RS09685	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HG264_RS09690	ENOG4105DR5	peptidase
HG264_RS09695	ENOG4105CUY	Mechanosensitive ion channel
HG264_RS09700	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HG264_RS09705	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
HG264_RS09710	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HG264_RS09715	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HG264_RS09720	ENOG4105N21	Membrane
HG264_RS09725	ENOG4105CUT	histidyl-tRNA synthetase
HG264_RS09730	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HG264_RS09750	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HG264_RS09755	ENOG4105C3J	Cysteine desulfurase
HG264_RS09760	ENOG4105D7W	serine acetyltransferase
HG264_RS09770	ENOG4105ECY	inositol monophosphatase
HG264_RS09775	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HG264_RS09780	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HG264_RS09785	ENOG4105VIE	preprotein translocase, subunit YajC
HG264_RS09790	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HG264_RS09810	ENOG4105E9Q	Acyl-transferase
HG264_RS09845	ENOG4105C84	Histidine ammonia-lyase
HG264_RS09875	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HG264_RS09885	ENOG4105C2D	reductase
HG264_RS09905	ENOG4105D25	secreted protein
HG264_RS09915	ENOG4108ZX5	transcriptional regulator
HG264_RS09920	ENOG4105C3M	thioredoxin reductase
HG264_RS09925	ENOG4105D3R	alkyl hydroperoxide reductase
HG264_RS09930	ENOG4105EXN	Sulfate transport protein CysZ
HG264_RS09945	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HG264_RS09950	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HG264_RS09955	ENOG4105C6K	Malic enzyme
HG264_RS09960	ENOG4106HNH	Acyl-transferase
HG264_RS09965	ENOG4108ZG0	Ompa motb domain protein
HG264_RS09970	ENOG4105C5X	domain protein
HG264_RS09975	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
HG264_RS09980	ENOG4105CK2	sodium dicarboxylate symporter
HG264_RS09985	ENOG41061ZR	Transcriptional regulator
HG264_RS09990	ENOG4105D25	secreted protein
HG264_RS09995	ENOG4105CEY	Amp-dependent synthetase and ligase
HG264_RS10000	ENOG4105CHU	acetyl-coa acetyltransferase
HG264_RS10015	ENOG4105C8Q	Methyl-accepting chemotaxis
HG264_RS10025	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HG264_RS10070	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
HG264_RS10080	ENOG4105BZU	Histidine kinase
HG264_RS10085	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HG264_RS10090	ENOG4105EYA	deoxyribonuclease
HG264_RS10100	ENOG4105E1F	short-chain dehydrogenase reductase
HG264_RS10120	ENOG4105BZU	Histidine kinase
HG264_RS10145	ENOG4105CEP	NADH dehydrogenase
HG264_RS10170	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HG264_RS10180	ENOG4105VEJ	Heat shock protein
HG264_RS10185	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HG264_RS10205	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
HG264_RS10210	ENOG4107RK2	ADP-ribose diphosphatase NudE
HG264_RS10215	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HG264_RS10220	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HG264_RS10225	ENOG4105D65	subunit l
HG264_RS10230	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HG264_RS10235	ENOG4107R4Z	monovalent cation h antiporter subunit d
HG264_RS10240	ENOG4105SC1	monovalent cation H antiporter subunit E
HG264_RS10245	ENOG4105W4C	monovalent cation H antiporter subunit F
HG264_RS10255	ENOG4108Q5Y	Membrane
HG264_RS10260	ENOG4105DSF	transport protein
HG264_RS10285	ENOG4105D6S	protein involved in catabolism of external DNA
HG264_RS10290	ENOG4107QHF	type ii secretion system protein e
HG264_RS10295	ENOG4105I7R	Adenylate cyclase
HG264_RS10300	ENOG4107IX6	phosphate transport regulator
HG264_RS10305	ENOG4105CJ3	phosphate transporter
HG264_RS10310	ENOG4105CWC	Acetylornithine deacetylase
HG264_RS10315	ENOG4105FYV	Amp nucleosidase
HG264_RS10320	ENOG4107QZM	n-acetylglutamate synthase
HG264_RS10325	ENOG4105C01	Dihydroxy-acid dehydratase
HG264_RS10330	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HG264_RS10335	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HG264_RS10340	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HG264_RS10345	ENOG4105HF0	Membrane
HG264_RS10355	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
HG264_RS10360	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HG264_RS10365	ENOG4108RXW	HAD-superfamily subfamily IB hydrolase
HG264_RS10375	ENOG4105VUC	UPF0237 protein
HG264_RS10385	ENOG4105CHR	reductase
HG264_RS10395	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HG264_RS10400	ENOG4105CAU	Arsenical resistance protein, ArsH
HG264_RS10405	ENOG4105CJW	magnesium transporter
HG264_RS10410	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HG264_RS10415	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HG264_RS10420	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HG264_RS10425	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
HG264_RS10430	ENOG4107QKW	extracellular solute-binding protein family 1
HG264_RS10435	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HG264_RS10440	ENOG4105D0A	hydroxylase
HG264_RS10445	ENOG4107RAQ	aminopeptidase
HG264_RS10460	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
HG264_RS10470	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HG264_RS10480	ENOG4105C7B	Threonine dehydratase
HG264_RS10485	ENOG4105E66	phosphoriboisomerase A
HG264_RS10495	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HG264_RS10500	ENOG4105CQB	FAD linked oxidase domain protein
HG264_RS10505	ENOG4108JQ1	Dehydrogenase
HG264_RS10510	ENOG4105EWC	Purine nucleoside phosphorylase
HG264_RS10525	ENOG4105E5G	Alpha beta hydrolase fold
HG264_RS10530	ENOG4107QP3	malate synthase g
HG264_RS10540	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HG264_RS10565	ENOG4105D05	Receptor
HG264_RS10570	ENOG4105CYM	Glutathione S-transferase
HG264_RS10590	ENOG4105J5J	Outer membrane porin
HG264_RS10605	ENOG4105EXC	Acyl-transferase
HG264_RS10615	ENOG4105FR1	rard protein
HG264_RS10630	ENOG4105EYW	Ion transport protein
HG264_RS10635	ENOG4105CNG	UPF0061 protein
HG264_RS10685	ENOG4105P8Q	Curli production assembly transport component CsgG
HG264_RS10690	ENOG4108WYR	Curli production assembly transport component, CsgF
HG264_RS10720	ENOG4105ECY	inositol monophosphatase
HG264_RS10750	ENOG4108RVA	ribokinase
HG264_RS10775	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HG264_RS10780	ENOG4105KSC	Transcriptional regulator, TraR DksA family
HG264_RS10785	ENOG4105C8Q	Methyl-accepting chemotaxis
HG264_RS10800	ENOG4105C8Q	Methyl-accepting chemotaxis
HG264_RS10820	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HG264_RS10830	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
HG264_RS10835	ENOG4105VFU	Rna-binding protein
HG264_RS10845	ENOG4105CBX	hi0933 family
HG264_RS10850	ENOG4107RI4	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HG264_RS10855	ENOG4108STX	response regulator
HG264_RS10860	ENOG4105BZU	Histidine kinase
HG264_RS10865	ENOG4105C1J	atp-dependent rna helicase
HG264_RS10900	ENOG4105D2N	Aldolase
HG264_RS10905	ENOG4105BZA	Phosphoglycerate kinase
HG264_RS10910	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HG264_RS10915	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HG264_RS10920	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
HG264_RS10925	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HG264_RS10935	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HG264_RS10940	ENOG4105SYT	Methylenetetrahydrofolate reductase
HG264_RS10945	ENOG4105C1J	atp-dependent rna helicase
HG264_RS10960	ENOG4105C1G	acyl-Coa dehydrogenase
HG264_RS10965	ENOG4105ETT	transcriptional Regulator, LysR family
HG264_RS10970	ENOG4108IPW	abc transporter atp-binding protein
HG264_RS10975	ENOG4105CM4	permease protein
HG264_RS10980	ENOG4105DHS	permease protein
HG264_RS10990	ENOG4108YYC	ycei family
HG264_RS10995	ENOG4105DS1	cytochrome b561
HG264_RS11000	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HG264_RS11005	ENOG4107QYG	anthranilate phosphoribosyltransferase
HG264_RS11010	ENOG4105DDQ	anthranilate synthase
HG264_RS11015	ENOG4105CRQ	synthase (Component I)
HG264_RS11025	ENOG4105DJV	ribulose-phosphate 3-epimerase
HG264_RS11030	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
HG264_RS11035	ENOG4108S0S	Nucleotidyl transferase
HG264_RS11040	ENOG4105EHM	Aminoglycoside phosphotransferase
HG264_RS11045	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HG264_RS11050	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HG264_RS11055	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HG264_RS11060	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HG264_RS11065	ENOG4105NWN	ApaG protein
HG264_RS11070	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HG264_RS11075	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HG264_RS11080	ENOG4105CYN	Serine protein kinase
HG264_RS11090	ENOG4105ED1	spovr family
HG264_RS11095	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HG264_RS11100	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HG264_RS11105	ENOG4107ZVW	dihydroneopterin aldolase
HG264_RS11115	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HG264_RS11120	ENOG4108RMV	DegV Family
HG264_RS11130	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HG264_RS11135	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HG264_RS11150	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HG264_RS11155	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HG264_RS11160	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HG264_RS11165	ENOG4105KI2	Urea amidohydrolase subunit beta
HG264_RS11170	ENOG4105CQM	Urea amidohydrolase subunit alpha
HG264_RS11175	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
HG264_RS11180	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HG264_RS11185	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HG264_RS11195	ENOG4105CTU	Proline racemase
HG264_RS11215	ENOG4108I0Y	(ABC) transporter
HG264_RS11220	ENOG4105CSU	acyl-Coa dehydrogenase
HG264_RS11225	ENOG4105CSU	acyl-Coa dehydrogenase
HG264_RS11235	ENOG4108IQK	o-acetylhomoserine
HG264_RS11240	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HG264_RS11245	ENOG4105BZ8	glutamate synthase
HG264_RS11250	ENOG4105CBC	glutamate synthase
HG264_RS11260	ENOG4105D49	3-dehydroquinate synthase
HG264_RS11265	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HG264_RS11270	ENOG4105E4G	Type IV pilus
HG264_RS11295	ENOG4108JQC	penicillin-binding protein 1A
HG264_RS11305	ENOG4108JJ8	(ABC) transporter
HG264_RS11310	ENOG4108JJ9	ABC, transporter
HG264_RS11315	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HG264_RS11320	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HG264_RS11325	ENOG41067MG	lrgb family
HG264_RS11335	ENOG4105BZU	Histidine kinase
HG264_RS11340	ENOG4105C1G	acyl-Coa dehydrogenase
HG264_RS11345	ENOG4105CC9	acyl-Coa dehydrogenase
HG264_RS11375	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
HG264_RS11380	ENOG4105CMR	udp-glucose 4-epimerase
HG264_RS11390	ENOG4105CQZ	Histidine kinase
HG264_RS11400	ENOG4105DQE	DNA ligase
HG264_RS11410	ENOG4105D8X	mechanosensitive ion channel
HG264_RS11445	ENOG4105BZU	Histidine kinase
HG264_RS11460	ENOG4105GN9	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HG264_RS11465	ENOG4108TGR	phosphatase
HG264_RS11470	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HG264_RS11475	ENOG4108YZT	Adenosylcobinamide kinase
HG264_RS11480	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HG264_RS11485	ENOG4105EFT	decarboxylase
HG264_RS11490	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HG264_RS11495	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
HG264_RS11500	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HG264_RS11505	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HG264_RS11515	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HG264_RS11530	ENOG4105S0E	allantoin catabolism protein
HG264_RS11540	ENOG410633P	Hydantoin racemase
HG264_RS11560	ENOG4105BZU	Histidine kinase
HG264_RS11565	ENOG4105BZU	Histidine kinase
HG264_RS11570	ENOG4107Z5C	methylesterase
HG264_RS11575	ENOG4105BZU	Histidine kinase
HG264_RS11580	ENOG4106H3A	restriction
HG264_RS11605	ENOG4105EXG	Transcriptional regulator
HG264_RS11640	ENOG4106PMH	Extracellular solute-binding protein family 3
HG264_RS11645	ENOG4108JEH	abc transporter atp-binding protein
HG264_RS11650	ENOG4108IPJ	Membrane
HG264_RS11665	ENOG4105CEN	a g-specific adenine glycosylase
HG264_RS11675	ENOG4105D5U	fad dependent oxidoreductase
HG264_RS11680	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HG264_RS11685	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HG264_RS11695	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HG264_RS11700	ENOG4105PXI	polysaccharide deacetylase
HG264_RS11705	ENOG4105CN1	protease
HG264_RS11710	ENOG41063SB	peptidase
HG264_RS11715	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HG264_RS11720	ENOG4107YZP	Rhodanese domain protein
HG264_RS11725	ENOG4105VW4	glutaredoxin 3
HG264_RS11730	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HG264_RS11735	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HG264_RS11740	ENOG4105PBF	Anti-RNA polymerase sigma 70 factor
HG264_RS11755	ENOG4105C5H	ABC transporter
HG264_RS11760	ENOG4108UPT	UPF0178 protein
HG264_RS11770	ENOG4105BZU	Histidine kinase
HG264_RS11775	ENOG4105D52	delta-aminolevulinic acid dehydratase
HG264_RS11785	ENOG4105C9X	ppx gppa phosphatase
HG264_RS11790	ENOG4105K63	Thioredoxin
HG264_RS11795	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HG264_RS11800	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HG264_RS11805	ENOG4107QK7	reductase
HG264_RS11815	ENOG410601J	HemY protein
HG264_RS11825	ENOG41076E6	Uroporphyrinogen-III Synthase
HG264_RS11830	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HG264_RS11835	ENOG4108NEV	two component transcriptional regulator, LytTR family
HG264_RS11845	ENOG4105CH7	arginosuccinase
HG264_RS11855	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
HG264_RS11860	ENOG4105DWY	Agmatine deiminase
HG264_RS11885	ENOG4105CFQ	glutamine synthetase
HG264_RS11890	ENOG4108Z86	Glutamine amidotransferase
HG264_RS11895	ENOG4105CFQ	glutamine synthetase
HG264_RS11900	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HG264_RS11905	ENOG4108HM4	ABC transporter
HG264_RS11910	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HG264_RS11915	ENOG4105F38	ABC transporter, permease
HG264_RS11920	ENOG4105D38	putrescine abc transporter
HG264_RS11925	ENOG41082JN	Transcriptional regulator
HG264_RS11945	ENOG4105CEY	Amp-dependent synthetase and ligase
HG264_RS11960	ENOG4107QX8	SPFH domain, Band 7 family protein
HG264_RS11980	ENOG410689M	(LipO)protein
HG264_RS11995	ENOG41090MY	MarR family Transcriptional regulator
HG264_RS12000	ENOG4105CAQ	asparagine synthetase
HG264_RS12005	ENOG4105D9M	gamma-glutamylcysteine synthetase
HG264_RS12010	ENOG4105DER	m42 family
HG264_RS12015	ENOG4105CHB	tonB-dependent Receptor
HG264_RS12020	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HG264_RS12030	ENOG4107RX2	synthase
HG264_RS12040	ENOG4105C0A	alcohol dehydrogenase
HG264_RS12050	ENOG4107XDR	Lactoylglutathione lyase
HG264_RS12055	ENOG4105CGU	Enoyl-CoA hydratase
HG264_RS12060	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HG264_RS12070	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HG264_RS12075	ENOG4105M08	Membrane
HG264_RS12080	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HG264_RS12085	ENOG4105D4P	Coproporphyrinogen iii oxidase
HG264_RS12105	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HG264_RS12110	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HG264_RS12115	ENOG4105CAK	Cell division ATP-binding protein ftsE
HG264_RS12120	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HG264_RS12130	ENOG4105C1V	Peptidase, M16
HG264_RS12135	ENOG4106H78	methyltransferase
HG264_RS12140	ENOG4107RGH	Aldehyde dehydrogenase
HG264_RS12155	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HG264_RS12160	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HG264_RS12180	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HG264_RS12195	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HG264_RS12200	ENOG4105CHU	acetyl-coa acetyltransferase
HG264_RS12220	ENOG4105CEY	Amp-dependent synthetase and ligase
HG264_RS12230	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HG264_RS12235	ENOG4105CC9	acyl-Coa dehydrogenase
HG264_RS12245	ENOG4105BZJ	Electron transfer flavoprotein
HG264_RS12250	ENOG4105C10	Electron transfer flavoprotein
HG264_RS12255	ENOG4108KK1	membrane protein AbrB duplication
HG264_RS12260	ENOG4105CFP	Peptidase U32
HG264_RS12265	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HG264_RS12285	ENOG4107QSN	dihydrolipoamide acetyltransferase
HG264_RS12290	ENOG4105CPP	Dehydrogenase, E1 component
HG264_RS12300	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HG264_RS12310	ENOG4107QS8	(LipO)protein
HG264_RS12315	ENOG4105BZU	Histidine kinase
HG264_RS12325	ENOG4105DR5	peptidase
HG264_RS12330	ENOG4105W0E	50S ribosomal protein L33
HG264_RS12335	ENOG4105KDC	50s ribosomal protein l28
HG264_RS12340	ENOG4105W5Q	DNA repair protein (RadC
HG264_RS12345	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HG264_RS12350	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HG264_RS12355	ENOG4107QKV	phosphomannomutase
HG264_RS12360	ENOG4105CAS	nag kinase
HG264_RS12375	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HG264_RS12390	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HG264_RS12395	ENOG4105DSJ	YicC domain protein
HG264_RS12400	ENOG4105EBR	Carboxylesterase
HG264_RS12420	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HG264_RS12430	ENOG4105CC0	LysR family Transcriptional regulator
HG264_RS12435	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HG264_RS12440	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HG264_RS12445	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HG264_RS12450	ENOG4105KME	endoribonuclease L-psp
HG264_RS12455	ENOG4108Z9K	Osmotically inducible protein
HG264_RS12470	ENOG4105CB5	ATP-dependent DNA helicase recG
HG264_RS12480	ENOG4105NYX	DNA-binding protein
HG264_RS12485	ENOG4107QZF	nitrite reductase NADPH large subunit
HG264_RS12495	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
HG264_RS12505	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HG264_RS12510	ENOG4105BZU	Histidine kinase
HG264_RS12515	ENOG4108VYJ	response regulator receiver protein
HG264_RS12535	ENOG4105C8U	phosphate abc transporter
HG264_RS12540	ENOG4105E2Z	phosphate ABC transporter (Permease
HG264_RS12545	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HG264_RS12550	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HG264_RS12555	ENOG4105NAU	thioesterase Superfamily protein
HG264_RS12560	ENOG4105C4R	Atp-dependent dna helicase
HG264_RS12565	ENOG4105BZU	Histidine kinase
HG264_RS12570	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HG264_RS12575	ENOG4106KNT	transcriptional regulator
HG264_RS12585	ENOG4108Y50	Glutathione-dependent formaldehyde-activating Gfa
HG264_RS12590	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HG264_RS12595	ENOG4105QNR	S1 RNA binding domain protein
HG264_RS12620	ENOG41074H6	response regulator
HG264_RS12625	ENOG4105DFK	Polyphosphate glucokinase
HG264_RS12630	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HG264_RS12640	ENOG4108NVR	Methyl-accepting chemotaxis
HG264_RS12660	ENOG4108Z0Z	intracellular protease Pfpi family
HG264_RS12670	ENOG4105DY2	Paraquat-inducible protein b
HG264_RS12675	ENOG4105F1S	paraquat-inducible protein a
HG264_RS12680	ENOG4105H2K	paraquat-inducible protein a
HG264_RS12700	ENOG4108V06	Glutathione peroxidase
HG264_RS12715	ENOG4107QZF	nitrite reductase NADPH large subunit
HG264_RS12720	ENOG4107QZF	nitrite reductase NADPH large subunit
HG264_RS12725	ENOG4105TMB	Formate nitrite transporter
HG264_RS12730	ENOG4105D9P	serine threonine protein kinase
HG264_RS12735	ENOG4105RX8	Protein of unknown function (DUF1523)
HG264_RS12770	ENOG4105BZU	Histidine kinase
HG264_RS12800	ENOG4105C8Q	Methyl-accepting chemotaxis
HG264_RS12820	ENOG4105C5H	ABC transporter
HG264_RS12850	ENOG4105BZW	Glycerate kinase
HG264_RS12855	ENOG4105C6Z	Gluconate
HG264_RS12860	ENOG4105DUM	transcriptional regulator, lysR family
HG264_RS12865	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HG264_RS12870	ENOG4107QSA	Oxaloacetate decarboxylase
HG264_RS12875	ENOG4107B2H	carbonic anhydrase
HG264_RS12880	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HG264_RS12885	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HG264_RS12890	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HG264_RS12895	ENOG4108Z0R	Transferase
HG264_RS12900	ENOG4105DGW	oligopeptidase A
HG264_RS12905	ENOG4105VKU	nucleicacid-binding protein
HG264_RS12920	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HG264_RS12925	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
HG264_RS12930	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
HG264_RS12950	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
HG264_RS12955	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HG264_RS12980	ENOG4106JUT	Streptomycin 3''-adenylyltransferase
HG264_RS13040	ENOG4105XDF	Protein of unknown function (DUF1272)
HG264_RS13075	ENOG4107QRT	dEAD DEAH box helicase
HG264_RS13080	ENOG4107T0X	DNA ligase
HG264_RS13085	ENOG4107T0X	DNA ligase
HG264_RS13090	ENOG4105FAV	ABC, transporter
HG264_RS13095	ENOG4105FDK	ABC transporter
HG264_RS13100	ENOG4105MYN	Zinc uptake regulation protein
HG264_RS13105	ENOG4105NXV	High-affinity zinc uptake system protein
HG264_RS13120	ENOG4105C2M	dna polymerase I
HG264_RS13125	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HG264_RS13130	ENOG4106RE7	Cytochrome
HG264_RS13135	ENOG4108Z33	Thiol disulfide Interchange Protein
HG264_RS13145	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HG264_RS13160	ENOG4105CJP	fad dependent oxidoreductase
HG264_RS13170	ENOG4107VRI	Transcriptional regulator
HG264_RS13190	ENOG4105C3M	thioredoxin reductase
HG264_RS13205	ENOG4105N1F	Hnh endonuclease
HG264_RS13225	ENOG4105P4J	Allophanate hydrolase, subunit 1
HG264_RS13230	ENOG4107R7A	Allophanate hydrolase subunit 2
HG264_RS13235	ENOG4105DWT	malate dehydrogenase (quinone)
HG264_RS13260	ENOG4105DAA	L-lactate
HG264_RS13265	ENOG41073TP	transcriptional regulator
HG264_RS13270	ENOG4105E08	Glycoside hydrolase, family 9
HG264_RS13290	ENOG4105KA7	cytochrome C
HG264_RS13295	ENOG4105CHH	sulfate transporter
HG264_RS13300	ENOG4105CWB	LysR family transcriptional Regulator
HG264_RS13305	ENOG4105CHF	Glutathione S-transferase
HG264_RS13310	ENOG4105C2I	pirin domain protein
HG264_RS13315	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HG264_RS13320	ENOG4108SB3	DoxX Family
HG264_RS13325	ENOG4105CH6	catalase
HG264_RS13335	ENOG4105CHR	reductase
HG264_RS13340	ENOG4105BZU	Histidine kinase
HG264_RS13345	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HG264_RS13380	ENOG4105DIA	mandelate racemase muconate lactonizing
HG264_RS13390	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HG264_RS13395	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HG264_RS13405	ENOG4108VUG	Enoyl-CoA hydratase
HG264_RS13410	ENOG4107QX3	carboxylase
HG264_RS13415	ENOG4105C1G	acyl-Coa dehydrogenase
HG264_RS13420	ENOG4105CIS	alcohol dehydrogenase
HG264_RS13435	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HG264_RS13440	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HG264_RS13445	ENOG4105E2X	shikimate dehydrogenase
HG264_RS13455	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HG264_RS13460	ENOG4105C79	DNA protecting protein DprA
HG264_RS13465	ENOG4108WZM	domain protein
HG264_RS13470	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HG264_RS13480	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HG264_RS13485	ENOG4105C1A	potassium transporter peripheral membrane
HG264_RS13490	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HG264_RS13505	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HG264_RS13515	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HG264_RS13520	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HG264_RS13540	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HG264_RS13545	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HG264_RS13550	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HG264_RS13555	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HG264_RS13560	ENOG4105VG0	50S ribosomal protein l34
HG264_RS13565	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HG264_RS13570	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HG264_RS13575	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HG264_RS13580	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HG264_RS13590	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HG264_RS13600	ENOG4107QJE	Chromosome Partitioning Protein
HG264_RS13605	ENOG4105FA0	parb-like partition protein
HG264_RS13610	ENOG41064MJ	ATP synthase, subunit I
HG264_RS13615	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HG264_RS13625	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HG264_RS13630	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HG264_RS13650	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HG264_RS13655	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HG264_RS13660	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HG264_RS13680	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HG264_RS13685	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HG264_RS13690	ENOG4105C1G	acyl-Coa dehydrogenase
HG264_RS13705	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
HG264_RS13710	ENOG4105CD5	CoA-binding domain protein
HG264_RS13715	ENOG4105CHR	reductase
HG264_RS13720	ENOG4108UKI	Enoyl-CoA hydratase
HG264_RS13725	ENOG4105C1G	acyl-Coa dehydrogenase
HG264_RS13730	ENOG4105X7H	acyl-CoA dehydrogenase
HG264_RS13755	ENOG4105C1G	acyl-Coa dehydrogenase
HG264_RS13760	ENOG4105DJG	MaoC domain protein dehydratase
HG264_RS13765	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HG264_RS13775	ENOG4105CI0	Citrate lyase
HG264_RS13780	ENOG4105CHR	reductase
HG264_RS13795	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HG264_RS13810	ENOG4105CKI	cobalamin synthesis protein
HG264_RS13820	ENOG4108R96	Methyltransferase, YaeB family
HG264_RS13835	ENOG4105D6J	arsenicaL-resistance protein
HG264_RS13840	ENOG4105CEY	Amp-dependent synthetase and ligase
HG264_RS13860	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HG264_RS13865	ENOG4105BZS	acriflavin resistance protein
HG264_RS13870	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HG264_RS13900	ENOG4105EHU	Circadian clock protein KaiC
HG264_RS13910	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
HG264_RS13925	ENOG4105CW7	secretion protein, HlyD family
HG264_RS13930	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HG264_RS14005	ENOG4105F8V	Hydrolase, tatD family
HG264_RS14010	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HG264_RS14025	ENOG4105DQ6	Transposase
HG264_RS14035	ENOG4105E3J	oxidoreductase
HG264_RS14055	ENOG41082SX	arsR family transcriptional regulator
HG264_RS14065	ENOG4105CAU	Arsenical resistance protein, ArsH
HG264_RS14070	ENOG4105D6J	arsenicaL-resistance protein
HG264_RS14105	ENOG4105VTR	Integrase
HG264_RS14120	ENOG4105CVR	type I restriction-modification system
HG264_RS14140	ENOG4105DZR	Type I site-specific deoxyribonuclease
HG264_RS14145	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
HG264_RS14170	ENOG4105C4R	Atp-dependent dna helicase
HG264_RS14175	ENOG4105BZU	Histidine kinase
HG264_RS14180	ENOG4105C0P	Mg chelatase subunit ChlI
HG264_RS14255	ENOG4108RAV	Conserved protein
HG264_RS14260	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HG264_RS14265	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HG264_RS14300	ENOG4105RJZ	Transcriptional regulator
HG264_RS14305	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HG264_RS14310	ENOG4105BZS	acriflavin resistance protein
HG264_RS14315	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HG264_RS14320	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HG264_RS14335	ENOG4105NI8	Cytosine-specific methyltransferase
HG264_RS14345	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HG264_RS14395	ENOG4108C33	Resolvase
HG264_RS14400	ENOG4108R0M	Aminoglycoside
HG264_RS14420	ENOG4107W31	Pentapeptide repeat protein
HG264_RS14505	ENOG4105C0P	Mg chelatase subunit ChlI
HG264_RS14510	ENOG4105W0Z	cytoplasmic protein
HG264_RS14515	ENOG4108YZA	Nitrogen regulatory protein pii
HG264_RS14525	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
HG264_RS14540	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
HG264_RS14545	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HG264_RS14560	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HG264_RS14570	ENOG4105XQ6	frataxin-like protein
HG264_RS14580	ENOG4105IU3	Glutathione S-transferase
HG264_RS14585	ENOG4105CSA	Coproporphyrinogen iii oxidase
HG264_RS14590	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HG264_RS14600	ENOG4105DWV	Homoserine O-trans-acetylase
HG264_RS14605	ENOG4105DWV	Homoserine O-trans-acetylase
HG264_RS14610	ENOG4105VZ9	UPF0235 protein
HG264_RS14615	ENOG4108VIA	integral membrane protein
HG264_RS14620	ENOG4105II7	pyrroline-5-carboxylate reductase
HG264_RS14625	ENOG4105DFA	alanine racemase domain protein
HG264_RS14630	ENOG4105CZX	twitching motility protein
HG264_RS14635	ENOG4105CZX	twitching motility protein
HG264_RS14640	ENOG4105CD3	dihydroorotase
HG264_RS14645	ENOG4105CXT	aspartate transcarbamylase
HG264_RS14650	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HG264_RS14655	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HG264_RS14660	ENOG4108UJU	UPF0301 protein
HG264_RS14670	ENOG4105D7Z	glutathione synthase
HG264_RS14675	ENOG4108UNF	response regulator
HG264_RS14680	ENOG4105M3Z	response regulator
HG264_RS14685	ENOG4108ZGA	chew protein
HG264_RS14690	ENOG4105C8Q	Methyl-accepting chemotaxis
HG264_RS14695	ENOG4105BZU	Histidine kinase
HG264_RS14715	ENOG4105E0F	Histidine kinase
HG264_RS14725	ENOG4105BZM	domain protein
HG264_RS14735	ENOG4105D9M	gamma-glutamylcysteine synthetase
HG264_RS14750	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HG264_RS14755	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HG264_RS14760	ENOG4105CUX	Signal transduction histidine kinase
HG264_RS14770	ENOG4105C5F	glutamine synthetase
HG264_RS14780	ENOG4105CI3	gtp-binding protein typa
HG264_RS14805	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HG264_RS14830	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HG264_RS14840	ENOG4105CHR	reductase
HG264_RS14860	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HG264_RS14870	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
HG264_RS14875	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HG264_RS14890	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HG264_RS14910	ENOG4108IG5	Transcriptional regulator
HG264_RS14925	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HG264_RS14930	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HG264_RS14945	ENOG4105C25	Primosomal protein n'
HG264_RS14960	ENOG4105C6K	Malic enzyme
HG264_RS14965	ENOG4106H31	ATP-dependent protease ATP-binding subunit-like protein
HG264_RS14970	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
HG264_RS14975	ENOG4108JUA	Transcriptional regulator
HG264_RS14990	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
HG264_RS14995	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HG264_RS15005	ENOG4105C0Z	ABC transporter
HG264_RS15010	ENOG4108IV0	ABC, transporter
HG264_RS15040	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HG264_RS15045	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HG264_RS15070	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HG264_RS15080	ENOG4105PM1	preprotein translocase subunit SecE
HG264_RS15085	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HG264_RS15095	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HG264_RS15105	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HG264_RS15110	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HG264_RS15120	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HG264_RS15125	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HG264_RS15130	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HG264_RS15140	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HG264_RS15145	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HG264_RS15150	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HG264_RS15155	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HG264_RS15160	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HG264_RS15165	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HG264_RS15170	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HG264_RS15175	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HG264_RS15180	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HG264_RS15185	ENOG41083MP	50s ribosomal protein l29
HG264_RS15195	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HG264_RS15200	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HG264_RS15205	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HG264_RS15215	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HG264_RS15220	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HG264_RS15225	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HG264_RS15230	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HG264_RS15235	ENOG4105VPB	50S ribosomal protein L30
HG264_RS15240	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HG264_RS15245	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HG264_RS15260	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HG264_RS15265	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HG264_RS15270	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HG264_RS15280	ENOG4105CH6	catalase
HG264_RS15285	ENOG4105EBR	Carboxylesterase
HG264_RS15290	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HG264_RS15295	ENOG4107RDB	Major Facilitator
HG264_RS15300	ENOG4108UUM	single-stranded DNA-binding protein
HG264_RS15315	ENOG4105EIF	outer membrane protein W
HG264_RS15335	ENOG4109015	Biopolymer transport protein exbD tolR
HG264_RS15340	ENOG410822N	TonB family
HG264_RS15350	ENOG4107QR8	Thioredoxin
HG264_RS15355	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HG264_RS15365	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HG264_RS15370	ENOG4105DN9	Na H antiporter
HG264_RS15380	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HG264_RS15385	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HG264_RS15390	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HG264_RS15395	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HG264_RS15400	ENOG4108ZAI	phosphatidylglycerophosphatase a
HG264_RS15405	ENOG4108WIW	Aspartyl protease
HG264_RS15410	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
HG264_RS15420	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HG264_RS15440	ENOG4105CTB	Polyprenyl synthetase
HG264_RS15445	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HG264_RS15450	ENOG4105EJ9	Membrane
HG264_RS15455	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HG264_RS15465	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HG264_RS15470	ENOG4108UKZ	OsmC family
HG264_RS15475	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
HG264_RS15480	ENOG4107YU2	histidine triad (hIT) protein
HG264_RS15505	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HG264_RS15515	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HG264_RS15520	ENOG4105DR5	peptidase
HG264_RS15525	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HG264_RS15555	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
HG264_RS15560	ENOG4108I5D	sulfate abc transporter
HG264_RS15565	ENOG4105ECW	sulfate abc transporter
HG264_RS15570	ENOG4108IJ6	ABC transporter
HG264_RS15580	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
HG264_RS15595	ENOG4105ER2	Ompa motb domain protein
HG264_RS15600	ENOG4105DSY	exodeoxyribonuclease V, gamma
HG264_RS15605	ENOG4107QKA	exodeoxyribonuclease V beta
HG264_RS15610	ENOG4107QYX	exodeoxyribonuclease v alpha
HG264_RS15615	ENOG4108Z86	Glutamine amidotransferase
HG264_RS15625	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HG264_RS15635	ENOG4105C94	Transporter
HG264_RS15665	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HG264_RS15670	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
HG264_RS15690	ENOG4105FGF	GDP-mannose mannosyl hydrolase
HG264_RS15695	ENOG4105C30	Nad-dependent epimerase dehydratase
HG264_RS15715	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HG264_RS15720	ENOG4105D3Q	Sugar transferase
HG264_RS15730	ENOG4108QV3	biosynthesis protein
HG264_RS15755	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HG264_RS15765	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HG264_RS15770	ENOG4105C8J	)-transporter
HG264_RS15775	ENOG4108Z1B	Cyclase dehydrase
HG264_RS15785	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HG264_RS15790	ENOG41090R7	Ferric uptake
HG264_RS15795	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HG264_RS15800	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HG264_RS15815	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HG264_RS15830	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HG264_RS15835	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HG264_RS15845	ENOG4105HBR	Rna-binding protein
HG264_RS15850	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HG264_RS15855	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HG264_RS15860	ENOG4105EEI	dihydropteroate synthase
HG264_RS15865	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HG264_RS15870	ENOG4105CP7	Triose-phosphate isomerase
HG264_RS15875	ENOG4105NTZ	Preprotein translocase subunit SecG
HG264_RS15895	ENOG4105CHV	Transcription elongation factor NusA
HG264_RS15900	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HG264_RS15905	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HG264_RS15910	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HG264_RS15915	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HG264_RS15920	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HG264_RS15935	ENOG4105I08	Pseudouridine synthase
HG264_RS15950	ENOG4107XID	2'-5' rna ligase
HG264_RS15975	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HG264_RS16000	ENOG4105CHU	acetyl-coa acetyltransferase
HG264_RS16005	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HG264_RS16010	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HG264_RS16015	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HG264_RS16020	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HG264_RS16025	ENOG4105DJ0	Poly(A) Polymerase
HG264_RS16030	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HG264_RS16035	ENOG4105BZU	Histidine kinase
HG264_RS16045	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HG264_RS16055	ENOG4105CHM	Aminotransferase
HG264_RS16060	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HG264_RS16070	ENOG4105EHG	Permease protein
HG264_RS16075	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HG264_RS16100	ENOG4105BZ4	penicillin-binding protein
HG264_RS16110	ENOG4105WP7	tRNA pseudouridine synthase C
HG264_RS16120	ENOG4105C7K	acetolactate synthase
HG264_RS16125	ENOG4108ZP8	Acetolactate synthase small subunit
HG264_RS16130	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HG264_RS16135	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HG264_RS16165	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HG264_RS16175	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HG264_RS16180	ENOG41077A9	carbonic anhydrase
HG264_RS16185	ENOG4105FDR	Membrane
HG264_RS16190	ENOG4105C26	Dehydrogenase
HG264_RS16200	ENOG4105D64	Mechanosensitive ion channel
HG264_RS16205	ENOG4105C3G	gtp-binding protein
HG264_RS16215	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HG264_RS16220	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HG264_RS16230	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HG264_RS16235	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
HG264_RS16240	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
HG264_RS16250	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HG264_RS16255	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HG264_RS16260	ENOG4105D06	uba thif-type nad fad binding protein
HG264_RS16265	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HG264_RS16270	ENOG41061N2	exported protein
HG264_RS16280	ENOG4108QDE	fad dependent oxidoreductase
HG264_RS16285	ENOG4105ECP	epimerase
HG264_RS16290	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HG264_RS16295	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HG264_RS16300	ENOG4105C5I	Dehydrogenase
HG264_RS16320	ENOG4105CWU	Biogenesis protein
HG264_RS16330	ENOG4105C2W	permease
HG264_RS16335	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HG264_RS16340	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HG264_RS16345	ENOG4105CHH	sulfate transporter
HG264_RS16365	ENOG4105K6T	rare lipoprotein A
HG264_RS16370	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HG264_RS16375	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HG264_RS16380	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HG264_RS16390	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HG264_RS16400	ENOG4108Z03	MAF-like protein
HG264_RS16405	ENOG4105C03	ribonuclease
HG264_RS16420	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HG264_RS16430	ENOG4105HDK	L-asparaginase
HG264_RS16445	ENOG4105DA5	(ABC) transporter
HG264_RS16450	ENOG4105E3A	(ABC) transporter
HG264_RS16465	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HG264_RS16470	ENOG4105BZP	glycoside hydrolase 15-related
HG264_RS16475	ENOG4106V8H	Nucleoid-associated protein
HG264_RS16480	ENOG4107QWE	)-transporter
HG264_RS16485	ENOG4107T2S	C-20 methyltransferase BchU
HG264_RS16535	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HG264_RS16550	ENOG4105CJ1	ABC, transporter
HG264_RS16560	ENOG4105C7J	ABC transporter, permease
HG264_RS16570	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HG264_RS16610	ENOG4105R8A	Heat shock protein
HG264_RS16615	ENOG4107QHF	type ii secretion system protein e
HG264_RS16640	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HG264_RS16665	ENOG4105K4T	epimerase
HG264_RS16670	ENOG4108VKG	metal-dependent hydrolase
HG264_RS16695	ENOG4105C2X	Arabinose 5-phosphate isomerase
HG264_RS16750	ENOG4105DTD	Dehydrogenase
HG264_RS16755	ENOG4105DMT	epimerase dehydratase
HG264_RS16760	ENOG4105C09	Bile acid
HG264_RS16765	ENOG4105H3G	oxidoreductase
HG264_RS16820	ENOG4105MYG	DNA polymerase iii, chi subunit
HG264_RS16825	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HG264_RS16830	ENOG4108M8S	permease YjgP YjgQ family protein
HG264_RS16835	ENOG4108K5H	permease YjgP YjgQ family protein
HG264_RS16850	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
HG264_RS16855	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HG264_RS16860	ENOG4105CSH	Transporter
HG264_RS16865	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HG264_RS16890	ENOG4105KKP	D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
HG264_RS16895	ENOG4105EUJ	GTP cyclohydrolase i
HG264_RS16900	ENOG410642E	Short chain dehydrogenase
HG264_RS16905	ENOG4105QDK	Flavodoxin
HG264_RS16915	ENOG4105MP9	class II Aldolase
HG264_RS16925	ENOG4105D1Q	UPF0246 protein
HG264_RS16930	ENOG4108IAB	Phoh family
HG264_RS16945	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HG264_RS16950	ENOG4105EGS	Mechanosensitive ion channel
HG264_RS16955	ENOG4105CSU	acyl-Coa dehydrogenase
HG264_RS16960	ENOG4105E27	serine threonine protein kinase
HG264_RS16965	ENOG4105MJ2	Competence protein
HG264_RS16970	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HG264_RS16975	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HG264_RS16980	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HG264_RS17000	ENOG4105CSU	acyl-Coa dehydrogenase
HG264_RS17005	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
HG264_RS17015	ENOG4105N42	UPF0307 protein
HG264_RS17020	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HG264_RS17025	ENOG41080Z8	PHOSPHOCARRIER protein
HG264_RS17030	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HG264_RS17035	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HG264_RS17040	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HG264_RS17045	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HG264_RS17050	ENOG4108IUZ	ABC transporter
HG264_RS17055	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HG264_RS17065	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HG264_RS17070	ENOG4105C2X	Arabinose 5-phosphate isomerase
HG264_RS17075	ENOG4105DHJ	ABC, transporter
HG264_RS17080	ENOG4105CY3	ABC transporter, permease
HG264_RS17115	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HG264_RS17120	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HG264_RS17130	ENOG4107QNR	UPF0135 protein
HG264_RS17135	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HG264_RS17140	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
HG264_RS17145	ENOG4108Z6B	deaminase
HG264_RS17150	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HG264_RS17155	ENOG4108ETH	Formylglycinamide ribotide synthetase
HG264_RS17160	ENOG4105UGU	tonB-dependent Receptor
HG264_RS17165	ENOG4105EGD	dinuclear metal center protein, YbgI family
HG264_RS17170	ENOG4105CA0	peroxidase
HG264_RS17180	ENOG4105E09	nadh pyrophosphatase
HG264_RS17190	ENOG4108Z0R	Transferase
HG264_RS17200	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HG264_RS17205	ENOG4108JU6	CBS domain protein
HG264_RS17215	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HG264_RS17220	ENOG4105K5M	30s ribosomal protein S16
HG264_RS17225	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HG264_RS17230	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HG264_RS17235	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HG264_RS17240	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HG264_RS17245	ENOG4105T95	Thiol disulfide interChange protein
HG264_RS17250	ENOG4105D6E	homoserine dehydrogenase
HG264_RS17255	ENOG4105D98	threonine synthase
HG264_RS17275	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
HG264_RS17280	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HG264_RS17315	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HG264_RS17350	ENOG4108302	MgtC SapB transporter
HG264_RS17355	ENOG4105FDF	Could be involved in DNA repair (By similarity)
HG264_RS17365	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
HG264_RS17370	ENOG4105CG3	alpha amylase, catalytic region
HG264_RS17375	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HG264_RS17380	ENOG4107UXM	Membrane
HG264_RS17385	ENOG4105DZQ	phospholipase D Transphosphatidylase
HG264_RS17390	ENOG4105X23	Endonuclease Exonuclease phosphatase
HG264_RS17430	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HG264_RS17435	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HG264_RS17440	ENOG4107TH8	cina domain protein
HG264_RS17445	ENOG4108VWS	Yaeq family
HG264_RS17450	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HG264_RS17460	ENOG4105BZU	Histidine kinase
HG264_RS17475	ENOG4105CRK	lysyL-tRNA synthetase
HG264_RS17490	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HG264_RS17495	ENOG4105E39	Enoyl-CoA hydratase
HG264_RS17510	ENOG4105Y75	tpr repeat protein
HG264_RS17520	ENOG4108IYU	L-aspartate oxidase
HG264_RS17525	ENOG4105EMN	RNA polymerase sigma factor
HG264_RS17530	ENOG41069E1	anti sigma-E protein RseA
HG264_RS17535	ENOG4105VQK	sigma E regulatory protein, MucB RseB
HG264_RS17545	ENOG4105C0H	protease
HG264_RS17550	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HG264_RS17555	ENOG4105C3F	Signal peptidase i
HG264_RS17565	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HG264_RS17570	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HG264_RS17590	ENOG4105BZU	Histidine kinase
HG264_RS17595	ENOG4105C6T	cysteine synthase
HG264_RS17605	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HG264_RS17610	ENOG4105DXN	mazG family
HG264_RS17620	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HG264_RS17630	ENOG41072GX	Peptidase M22 Glycoprotease
HG264_RS17640	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
HG264_RS17650	ENOG4105CJ1	ABC, transporter
HG264_RS17670	ENOG4105K63	Thioredoxin
HG264_RS17680	ENOG4105DHI	Methyltransferase
HG264_RS17695	ENOG4105CUZ	uba thif-type nad fad binding protein
HG264_RS17700	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
HG264_RS17705	ENOG4105KUZ	arsenate reductase
HG264_RS17710	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
HG264_RS17715	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HG264_RS17720	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HG264_RS17725	ENOG4105CE9	30S ribosomal protein S2
HG264_RS17730	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HG264_RS17735	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HG264_RS17740	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HG264_RS17745	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HG264_RS17750	ENOG4105KNE	Phosphatidate cytidylyltransferase
HG264_RS17760	ENOG4105DZP	Membrane-associated zinc metalloprotease
HG264_RS17770	ENOG4105X4K	outer membrane chaperone skp
HG264_RS17775	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HG264_RS17780	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HG264_RS17785	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HG264_RS17790	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HG264_RS17795	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HG264_RS17800	ENOG4105C0B	DNA polymerase III (alpha subunit)
HG264_RS17805	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HG264_RS17810	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HG264_RS17815	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HG264_RS17820	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HG264_RS17825	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HG264_RS17830	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HG264_RS17835	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HG264_RS17850	ENOG4105C0B	DNA polymerase III (alpha subunit)
HG264_RS17855	ENOG4105C1G	acyl-Coa dehydrogenase
HG264_RS17860	ENOG4105E39	Enoyl-CoA hydratase
HG264_RS17865	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HG264_RS17875	ENOG4105C26	Dehydrogenase
HG264_RS17885	ENOG4105C8F	Beta-lactamase domain protein
HG264_RS17895	ENOG4105CEY	Amp-dependent synthetase and ligase
HG264_RS17900	ENOG4105BZU	Histidine kinase
HG264_RS17920	ENOG4105BZU	Histidine kinase
HG264_RS17935	ENOG4105H1G	trap transporter solute receptor taxi family
HG264_RS17940	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HG264_RS17950	ENOG4105CHR	reductase
HG264_RS17970	ENOG4105K5B	UPF0225 protein
HG264_RS17980	ENOG4105DVT	helicase
HG264_RS17990	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HG264_RS18000	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HG264_RS18005	ENOG4105C29	acyl-CoA thioesterase
HG264_RS18025	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HG264_RS18030	ENOG4105BZG	amino acid carrier protein
HG264_RS18045	ENOG4106A72	regulatory protein AmpE
HG264_RS18050	ENOG4108NVR	Methyl-accepting chemotaxis
HG264_RS18055	ENOG4108WBT	adenosyltransferase
HG264_RS18060	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HG264_RS18065	ENOG4108VYJ	response regulator receiver protein
HG264_RS18070	ENOG4108VPT	UPF0234 protein
HG264_RS18075	ENOG4105D64	Mechanosensitive ion channel
HG264_RS18090	ENOG41080UX	Methyltransferase
HG264_RS18110	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HG264_RS18120	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HG264_RS18125	ENOG4105CEY	Amp-dependent synthetase and ligase
HG264_RS18135	ENOG4105C8Q	Methyl-accepting chemotaxis
HG264_RS18140	ENOG4105FS0	cytoplasmic membrane protein
HG264_RS18145	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HG264_RS18155	ENOG4108Z4U	Ferredoxin
HG264_RS18165	ENOG4105CEY	Amp-dependent synthetase and ligase
HG264_RS18185	ENOG4107TH8	cina domain protein
HG264_RS18190	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HG264_RS18195	ENOG4105Y3E	Modulates RecA activity (By similarity)
HG264_RS18205	ENOG4105CY0	Metallo-Beta-Lactamase
HG264_RS18225	ENOG41080IJ	Diacylglycerol kinase
HG264_RS18230	ENOG4105BZU	Histidine kinase
HG264_RS18245	ENOG4107QF7	multi-drug
HG264_RS18255	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HG264_RS18265	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HG264_RS18270	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HG264_RS18280	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HG264_RS18285	ENOG4105DZR	Type I site-specific deoxyribonuclease
HG264_RS18310	ENOG4105EKX	Restriction modification system DNA (Specificity
HG264_RS18315	ENOG4105CVR	type I restriction-modification system
HG264_RS18320	ENOG4105KT5	UmuD protein
HG264_RS18325	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HG264_RS18360	ENOG4105EXG	Transcriptional regulator
HG264_RS18405	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HG264_RS18420	ENOG4105EMN	RNA polymerase sigma factor