locus-tag	class	description
PS273GM_RS00005	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PS273GM_RS00035	COG0405	Gamma-glutamyltransferase
PS273GM_RS00040	COG5002	protein histidine kinase activity
PS273GM_RS00040	COG2205	protein histidine kinase activity
PS273GM_RS00040	COG0784	Response regulator, receiver
PS273GM_RS00045	COG2860	membrane
PS273GM_RS00055	COG2977	Belongs to the P-Pant transferase superfamily
PS273GM_RS00060	COG2205	protein histidine kinase activity
PS273GM_RS00065	COG0745	RESPONSE REGULATOR receiver
PS273GM_RS00070	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PS273GM_RS00070	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PS273GM_RS00090	COG1943	Transposase
PS273GM_RS00110	COG0583	DNA-binding transcription factor activity
PS273GM_RS00115	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PS273GM_RS00145	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PS273GM_RS00160	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PS273GM_RS00175	COG2226	methyltransferase
PS273GM_RS00205	COG1733	regulation of RNA biosynthetic process
PS273GM_RS00235	COG4771	TonB-dependent receptor
PS273GM_RS00255	COG3459	Glycosyltransferase 36 associated
PS273GM_RS00260	COG4774	siderophore transport
PS273GM_RS00265	COG0826	peptidase U32
PS273GM_RS00275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PS273GM_RS00285	COG2814	Major facilitator Superfamily
PS273GM_RS00295	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS00315	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
PS273GM_RS00325	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PS273GM_RS00340	COG0069	glutamate synthase activity
PS273GM_RS00365	COG1283	sodium-dependent phosphate transmembrane transporter activity
PS273GM_RS00375	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PS273GM_RS00380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PS273GM_RS00405	COG0668	transmembrane transport
PS273GM_RS00410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PS273GM_RS00415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PS273GM_RS00430	COG0483	inositol monophosphate 1-phosphatase activity
PS273GM_RS00450	COG0742	ribosomal rna small subunit methyltransferase
PS273GM_RS00460	COG1801	Protein of unknown function DUF72
PS273GM_RS00470	COG1214	PFAM Peptidase M22, glycoprotease
PS273GM_RS00480	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PS273GM_RS00495	COG2885	chlorophyll binding
PS273GM_RS00505	COG0318	PFAM AMP-dependent synthetase and ligase
PS273GM_RS00510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PS273GM_RS00515	COG0235	Class ii aldolase
PS273GM_RS00520	COG0318	PFAM AMP-dependent synthetase and ligase
PS273GM_RS00535	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS00550	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PS273GM_RS00560	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PS273GM_RS00570	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PS273GM_RS00580	COG1902	pentaerythritol trinitrate reductase activity
PS273GM_RS00585	COG3383	formate dehydrogenase (NAD+) activity
PS273GM_RS00590	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PS273GM_RS00595	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PS273GM_RS00600	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PS273GM_RS00605	COG1984	allophanate hydrolase subunit 2
PS273GM_RS00620	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PS273GM_RS00630	COG3842	ATPase activity
PS273GM_RS00635	COG0590	tRNA wobble adenosine to inosine editing
PS273GM_RS00640	COG2132	Multicopper oxidase
PS273GM_RS00660	COG3039	Transposase
PS273GM_RS00675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PS273GM_RS00680	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PS273GM_RS00715	COG2116	formate transmembrane transporter activity
PS273GM_RS00755	COG3387	PFAM Glycoside hydrolase 15-related
PS273GM_RS00770	COG3039	Transposase
PS273GM_RS00825	COG0156	8-amino-7-oxononanoate synthase activity
PS273GM_RS00840	COG0367	asparagine synthase
PS273GM_RS00845	COG2814	Major facilitator Superfamily
PS273GM_RS00850	COG0583	DNA-binding transcription factor activity
PS273GM_RS00855	COG5642	Protein of unknown function (DUF2384)
PS273GM_RS00860	COG5654	RES domain protein
PS273GM_RS00865	COG2948	multi-organism process
PS273GM_RS00880	COG3846	protein secretion by the type IV secretion system
PS273GM_RS00895	COG3451	type IV secretory pathway VirB4
PS273GM_RS00905	COG3838	Conjugal transfer protein Trbc
PS273GM_RS00910	COG4962	Type ii secretion system protein e
PS273GM_RS00945	COG1192	Involved in chromosome partitioning
PS273GM_RS00965	COG5489	Protein of unknown function (DUF736)
PS273GM_RS00975	COG3039	Transposase
PS273GM_RS00990	COG1280	lysine exporter protein (LysE YggA)
PS273GM_RS01010	COG2003	Belongs to the UPF0758 family
PS273GM_RS01035	COG1309	transcriptional regulator
PS273GM_RS01055	COG0582	viral genome integration into host DNA
PS273GM_RS01060	COG0519	Catalyzes the synthesis of GMP from XMP
PS273GM_RS01060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PS273GM_RS01075	COG1570	exodeoxyribonuclease VII activity
PS273GM_RS01080	COG0739	heme binding
PS273GM_RS01085	COG1335	isochorismatase
PS273GM_RS01090	COG0668	transmembrane transport
PS273GM_RS01105	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PS273GM_RS01110	COG1064	alcohol dehydrogenase
PS273GM_RS01120	COG2356	endonuclease I
PS273GM_RS01125	COG3647	Membrane
PS273GM_RS01140	COG0436	Aminotransferase
PS273GM_RS01145	COG1045	serine acetyltransferase
PS273GM_RS01150	COG1160	GTP binding
PS273GM_RS01160	COG2976	Protein conserved in bacteria
PS273GM_RS01165	COG0124	histidyl-tRNA synthetase
PS273GM_RS01170	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PS273GM_RS01175	COG1426	Protein conserved in bacteria
PS273GM_RS01185	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PS273GM_RS01190	COG0105	UTP biosynthetic process
PS273GM_RS01205	COG0443	Heat shock 70 kDa protein
PS273GM_RS01210	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PS273GM_RS01215	COG0316	Belongs to the HesB IscA family
PS273GM_RS01225	COG1104	cysteine desulfurase activity
PS273GM_RS01250	COG3134	Outer membrane lipoprotein
PS273GM_RS01265	COG1862	Preprotein translocase
PS273GM_RS01285	COG1278	Cold shock
PS273GM_RS01295	COG0795	lipopolysaccharide-transporting ATPase activity
PS273GM_RS01300	COG0795	lipopolysaccharide-transporting ATPase activity
PS273GM_RS01305	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PS273GM_RS01335	COG0477	Major facilitator Superfamily
PS273GM_RS01340	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
PS273GM_RS01355	COG3081	Nucleoid-associated protein
PS273GM_RS01360	COG1968	undecaprenyl-diphosphatase activity
PS273GM_RS01370	COG2827	Endonuclease containing a URI domain
PS273GM_RS01375	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PS273GM_RS01385	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PS273GM_RS01390	COG0583	DNA-binding transcription factor activity
PS273GM_RS01415	COG3530	Putative quorum-sensing-regulated virulence factor
PS273GM_RS01425	COG0667	Aldo Keto reductase
PS273GM_RS01435	COG2814	Major facilitator Superfamily
PS273GM_RS01455	COG0490	domain, Protein
PS273GM_RS01455	COG0471	metal ion transport
PS273GM_RS01485	COG2733	membrane
PS273GM_RS01490	COG1116	anion transmembrane transporter activity
PS273GM_RS01505	COG0537	adenosine 5'-monophosphoramidase activity
PS273GM_RS01510	COG0625	glutathione transferase activity
PS273GM_RS01555	COG0730	response to heat
PS273GM_RS01560	COG1234	tRNA 3'-trailer cleavage
PS273GM_RS01570	COG1643	Atp-dependent helicase
PS273GM_RS01585	COG0318	PFAM AMP-dependent synthetase and ligase
PS273GM_RS01590	COG0318	PFAM AMP-dependent synthetase and ligase
PS273GM_RS01595	COG2030	dehydratase
PS273GM_RS01610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PS273GM_RS01615	COG1201	RNA secondary structure unwinding
PS273GM_RS01630	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PS273GM_RS01645	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PS273GM_RS01660	COG0513	Belongs to the DEAD box helicase family
PS273GM_RS01690	COG0443	Heat shock 70 kDa protein
PS273GM_RS01695	COG2271	Major facilitator Superfamily
PS273GM_RS01700	COG3622	Belongs to the hyi family
PS273GM_RS01705	COG2084	Dehydrogenase
PS273GM_RS01725	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PS273GM_RS01735	COG3639	organic phosphonate transmembrane transporter activity
PS273GM_RS01800	COG0402	S-adenosylhomocysteine deaminase activity
PS273GM_RS01810	COG1802	Transcriptional regulator
PS273GM_RS01815	COG2252	PERMEase
PS273GM_RS01840	COG4266	Belongs to the allantoicase family
PS273GM_RS01845	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
PS273GM_RS01855	COG2233	PERMEase
PS273GM_RS01860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PS273GM_RS01860	COG4651	solute:proton antiporter activity
PS273GM_RS01865	COG2233	PERMEase
PS273GM_RS01875	COG0840	transmembrane signaling receptor activity
PS273GM_RS01905	COG1704	LemA family
PS273GM_RS01935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PS273GM_RS01940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PS273GM_RS01945	COG0459	protein refolding
PS273GM_RS01950	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PS273GM_RS01955	COG3030	protein affecting phage T7 exclusion by the F plasmid
PS273GM_RS01965	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS01975	COG3695	enzyme binding
PS273GM_RS01985	COG0668	transmembrane transport
PS273GM_RS01990	COG1666	GTP binding
PS273GM_RS01995	COG0745	RESPONSE REGULATOR receiver
PS273GM_RS02005	COG4191	Histidine kinase
PS273GM_RS02010	COG2096	Adenosyltransferase
PS273GM_RS02040	COG0494	nUDIX hydrolase
PS273GM_RS02045	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PS273GM_RS02050	COG0653	protein targeting
PS273GM_RS02090	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PS273GM_RS02095	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PS273GM_RS02115	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PS273GM_RS02120	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PS273GM_RS02130	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PS273GM_RS02135	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PS273GM_RS02145	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
PS273GM_RS02150	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PS273GM_RS02170	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PS273GM_RS02190	COG1408	metallophosphoesterase
PS273GM_RS02220	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
PS273GM_RS02220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PS273GM_RS02230	COG0288	reversible hydration of carbon dioxide
PS273GM_RS02235	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
PS273GM_RS02250	COG0456	acetyltransferase
PS273GM_RS02260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PS273GM_RS02270	COG0019	diaminopimelate decarboxylase activity
PS273GM_RS02315	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
PS273GM_RS02325	COG1183	phosphatidylcholine synthase activity
PS273GM_RS02330	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PS273GM_RS02340	COG0028	Belongs to the TPP enzyme family
PS273GM_RS02350	COG3098	single-species biofilm formation
PS273GM_RS02360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PS273GM_RS02370	COG2226	methyltransferase
PS273GM_RS02395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PS273GM_RS02410	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PS273GM_RS02425	COG2264	protein methyltransferase activity
PS273GM_RS02445	COG0138	bifunctional purine biosynthesis protein purh
PS273GM_RS02450	COG0151	Belongs to the GarS family
PS273GM_RS02455	COG0784	Response regulator, receiver
PS273GM_RS02455	COG2205	protein histidine kinase activity
PS273GM_RS02455	COG5002	protein histidine kinase activity
PS273GM_RS02460	COG2124	cytochrome p450
PS273GM_RS02475	COG0679	Auxin Efflux Carrier
PS273GM_RS02500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PS273GM_RS02515	COG1181	Belongs to the D-alanine--D-alanine ligase family
PS273GM_RS02520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PS273GM_RS02525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PS273GM_RS02530	COG0772	Belongs to the SEDS family
PS273GM_RS02535	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PS273GM_RS02540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PS273GM_RS02545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PS273GM_RS02550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PS273GM_RS02565	COG0275	rRNA processing
PS273GM_RS02585	COG3107	peptidoglycan biosynthetic process
PS273GM_RS02590	COG0792	nuclease activity
PS273GM_RS02595	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PS273GM_RS02600	COG2823	Periplasmic or secreted lipoprotein
PS273GM_RS02605	COG2969	positive regulation of protein catabolic process
PS273GM_RS02610	COG0625	glutathione transferase activity
PS273GM_RS02615	COG2857	Cytochrome c1
PS273GM_RS02620	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PS273GM_RS02625	COG0723	plastoquinol--plastocyanin reductase activity
PS273GM_RS02630	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PS273GM_RS02635	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PS273GM_RS02640	COG0667	Aldo Keto reductase
PS273GM_RS02655	COG0237	dephospho-CoA kinase activity
PS273GM_RS02660	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PS273GM_RS02700	COG0175	sulfate reduction
PS273GM_RS02710	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PS273GM_RS02720	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PS273GM_RS02725	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PS273GM_RS02730	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PS273GM_RS02755	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PS273GM_RS02760	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PS273GM_RS02765	COG1127	ABC transporter
PS273GM_RS02775	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PS273GM_RS02790	COG1137	ATPase activity
PS273GM_RS02795	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PS273GM_RS02810	COG1660	Displays ATPase and GTPase activities
PS273GM_RS02820	COG0312	modulator of DNA gyrase
PS273GM_RS02830	COG0312	modulator of DNA gyrase
PS273GM_RS02835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PS273GM_RS02845	COG1530	ribonuclease E activity
PS273GM_RS02850	COG0424	maF-like protein
PS273GM_RS02860	COG1792	Involved in formation and maintenance of cell shape
PS273GM_RS02865	COG1077	Cell shape determining protein MreB Mrl
PS273GM_RS02870	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PS273GM_RS02880	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PS273GM_RS02885	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PS273GM_RS02890	COG0530	calcium, potassium:sodium antiporter activity
PS273GM_RS02895	COG0530	calcium, potassium:sodium antiporter activity
PS273GM_RS02905	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PS273GM_RS02920	COG0019	diaminopimelate decarboxylase activity
PS273GM_RS02925	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PS273GM_RS02950	COG4993	Dehydrogenase
PS273GM_RS02955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PS273GM_RS02955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PS273GM_RS02955	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PS273GM_RS02960	COG1105	Belongs to the carbohydrate kinase PfkB family
PS273GM_RS02965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PS273GM_RS02965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PS273GM_RS02985	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PS273GM_RS03015	COG0534	Mate efflux family protein
PS273GM_RS03025	COG0753	catalase activity
PS273GM_RS03030	COG1115	amino acid carrier protein
PS273GM_RS03115	COG0489	protein tyrosine kinase activity
PS273GM_RS03115	COG3206	protein involved in exopolysaccharide biosynthesis
PS273GM_RS03130	COG2133	pyrroloquinoline quinone binding
PS273GM_RS03140	COG1253	flavin adenine dinucleotide binding
PS273GM_RS03150	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PS273GM_RS03170	COG1309	transcriptional regulator
PS273GM_RS03205	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PS273GM_RS03210	COG0583	DNA-binding transcription factor activity
PS273GM_RS03220	COG2814	Major facilitator Superfamily
PS273GM_RS03225	COG1309	transcriptional regulator
PS273GM_RS03250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PS273GM_RS03255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PS273GM_RS03260	COG1538	Outer membrane efflux protein
PS273GM_RS03270	COG2169	Transcriptional regulator
PS273GM_RS03270	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PS273GM_RS03280	COG0084	hydrolase, TatD family'
PS273GM_RS03300	COG1515	deoxyribonuclease V activity
PS273GM_RS03305	COG4977	sequence-specific DNA binding
PS273GM_RS03310	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PS273GM_RS03315	COG0180	Tryptophanyl-tRNA synthetase
PS273GM_RS03345	COG1252	NADH dehydrogenase
PS273GM_RS03415	COG1032	radical SAM domain protein
PS273GM_RS03420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PS273GM_RS03425	COG0305	Participates in initiation and elongation during chromosome replication
PS273GM_RS03430	COG0359	binds to the 23S rRNA
PS273GM_RS03440	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PS273GM_RS03445	COG0360	Binds together with S18 to 16S ribosomal RNA
PS273GM_RS03450	COG0784	Response regulator, receiver
PS273GM_RS03450	COG4191	Histidine kinase
PS273GM_RS03455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PS273GM_RS03460	COG0557	exoribonuclease II activity
PS273GM_RS03475	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PS273GM_RS03480	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PS273GM_RS03485	COG0330	HflC and HflK could
PS273GM_RS03490	COG0330	HflC and HflK could
PS273GM_RS03495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PS273GM_RS03500	COG1923	regulation of RNA biosynthetic process
PS273GM_RS03505	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PS273GM_RS03515	COG0860	N-Acetylmuramoyl-L-alanine amidase
PS273GM_RS03520	COG0802	atpase or kinase
PS273GM_RS03525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PS273GM_RS03525	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PS273GM_RS03540	COG4948	Mandelate Racemase Muconate Lactonizing
PS273GM_RS03545	COG0800	Aldolase
PS273GM_RS03550	COG3734	2-keto-3-deoxy-galactonokinase
PS273GM_RS03555	COG1172	Belongs to the binding-protein-dependent transport system permease family
PS273GM_RS03560	COG1129	ABC transporter
PS273GM_RS03565	COG1879	ABC-type sugar transport system periplasmic component
PS273GM_RS03570	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS03580	COG2186	Transcriptional regulator
PS273GM_RS03600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PS273GM_RS03610	COG0531	amino acid
PS273GM_RS03615	COG4303	Ethanolamine ammonia lyase large subunit
PS273GM_RS03635	COG3228	Belongs to the MtfA family
PS273GM_RS03645	COG4191	Histidine kinase
PS273GM_RS03645	COG0784	Response regulator, receiver
PS273GM_RS03650	COG3546	catalase activity
PS273GM_RS03655	COG4067	protein conserved in archaea
PS273GM_RS03655	COG0189	ligase activity
PS273GM_RS03670	COG1230	cation diffusion facilitator family transporter
PS273GM_RS03680	COG0730	response to heat
PS273GM_RS03685	COG1722	exodeoxyribonuclease VII activity
PS273GM_RS03690	COG0142	geranyltranstransferase activity
PS273GM_RS03695	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PS273GM_RS03700	COG4206	TonB-dependent receptor
PS273GM_RS03715	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PS273GM_RS03720	COG3577	Aspartyl protease
PS273GM_RS03725	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
PS273GM_RS03730	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PS273GM_RS03735	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PS273GM_RS03740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PS273GM_RS03765	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PS273GM_RS03765	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PS273GM_RS03780	COG2264	protein methyltransferase activity
PS273GM_RS03790	COG3118	belongs to the thioredoxin family
PS273GM_RS03800	COG1946	Acyl-CoA thioesterase
PS273GM_RS03810	COG0123	including yeast histone deacetylase and acetoin utilization protein
PS273GM_RS03835	COG0513	Belongs to the DEAD box helicase family
PS273GM_RS03855	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS03865	COG1643	Atp-dependent helicase
PS273GM_RS03880	COG1522	sequence-specific DNA binding
PS273GM_RS03915	COG0411	ABC transporter
PS273GM_RS03925	COG4221	oxidoreductase activity
PS273GM_RS03935	COG0410	ABC transporter
PS273GM_RS03950	COG0559	Belongs to the binding-protein-dependent transport system permease family
PS273GM_RS03955	COG0829	nickel cation binding
PS273GM_RS03960	COG0831	urea catabolic process
PS273GM_RS03975	COG0832	Belongs to the urease beta subunit family
PS273GM_RS03980	COG0804	urea catabolic process
PS273GM_RS03985	COG1953	Uracil, thiamine, allantoin
PS273GM_RS04000	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PS273GM_RS04010	COG2814	Major facilitator Superfamily
PS273GM_RS04015	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PS273GM_RS04030	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
PS273GM_RS04035	COG0830	nickel cation binding
PS273GM_RS04040	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PS273GM_RS04055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PS273GM_RS04060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PS273GM_RS04070	COG1960	acyl-CoA dehydrogenase activity
PS273GM_RS04075	COG2205	protein histidine kinase activity
PS273GM_RS04075	COG3437	response regulator, receiver
PS273GM_RS04075	COG3850	Histidine kinase
PS273GM_RS04075	COG4999	Histidine kinase
PS273GM_RS04080	COG0352	thiamine-phosphate diphosphorylase activity
PS273GM_RS04080	COG0351	phosphomethylpyrimidine kinase
PS273GM_RS04085	COG0352	thiamine-phosphate diphosphorylase activity
PS273GM_RS04090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PS273GM_RS04105	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PS273GM_RS04110	COG1702	phosphate starvation-inducible protein PhoH
PS273GM_RS04115	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PS273GM_RS04120	COG4535	Mg2 and Co2 transporter CorC
PS273GM_RS04125	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PS273GM_RS04140	COG0495	leucyl-tRNA aminoacylation
PS273GM_RS04160	COG2951	lytic endotransglycosylase activity
PS273GM_RS04165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PS273GM_RS04170	COG0321	lipoyl(octanoyl) transferase activity
PS273GM_RS04175	COG2921	Belongs to the UPF0250 family
PS273GM_RS04180	COG1686	Belongs to the peptidase S11 family
PS273GM_RS04190	COG2951	lytic endotransglycosylase activity
PS273GM_RS04195	COG0772	Belongs to the SEDS family
PS273GM_RS04200	COG0768	penicillin binding
PS273GM_RS04205	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PS273GM_RS04215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PS273GM_RS04220	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PS273GM_RS04225	COG0586	Pfam SNARE associated Golgi protein
PS273GM_RS04235	COG1346	cytolysis
PS273GM_RS04255	COG0702	epimerase
PS273GM_RS04260	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PS273GM_RS04270	COG1162	GTPase activity
PS273GM_RS04275	COG1360	Flagellar Motor Protein
PS273GM_RS04280	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PS273GM_RS04295	COG0688	phosphatidylethanolamine metabolic process
PS273GM_RS04305	COG2200	EAL domain
PS273GM_RS04310	COG1063	alcohol dehydrogenase
PS273GM_RS04315	COG3830	Belongs to the UPF0237 family
PS273GM_RS04315	COG0560	Phosphoserine phosphatase
PS273GM_RS04335	COG3577	Aspartyl protease
PS273GM_RS04350	COG3150	esterase
PS273GM_RS04355	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PS273GM_RS04365	COG0494	nUDIX hydrolase
PS273GM_RS04385	COG3547	Transposase (IS116 IS110 IS902 family)
PS273GM_RS04390	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PS273GM_RS04395	COG1538	Outer membrane efflux protein
PS273GM_RS04400	COG1519	Transferase
PS273GM_RS04415	COG0667	Aldo Keto reductase
PS273GM_RS04425	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PS273GM_RS04425	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PS273GM_RS04430	COG1132	(ABC) transporter
PS273GM_RS04445	COG0110	maltose O-acetyltransferase activity
PS273GM_RS04450	COG1215	transferase activity, transferring glycosyl groups
PS273GM_RS04460	COG1215	transferase activity, transferring glycosyl groups
PS273GM_RS04470	COG2192	nodulation
PS273GM_RS04495	COG0438	transferase activity, transferring glycosyl groups
PS273GM_RS04505	COG0859	PFAM glycosyl transferase family 9
PS273GM_RS04515	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PS273GM_RS04540	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PS273GM_RS04545	COG1960	acyl-CoA dehydrogenase activity
PS273GM_RS04550	COG1960	acyl-CoA dehydrogenase activity
PS273GM_RS04560	COG1960	acyl-CoA dehydrogenase activity
PS273GM_RS04580	COG1073	alpha beta
PS273GM_RS04580	COG2226	methyltransferase
PS273GM_RS04585	COG0156	8-amino-7-oxononanoate synthase activity
PS273GM_RS04590	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PS273GM_RS04595	COG1040	competence protein
PS273GM_RS04600	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PS273GM_RS04605	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PS273GM_RS04650	COG1960	acyl-CoA dehydrogenase activity
PS273GM_RS04655	COG3263	regulation of cellular component size
PS273GM_RS04660	COG3264	Mechanosensitive ion channel
PS273GM_RS04660	COG1196	nuclear chromosome segregation
PS273GM_RS04665	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PS273GM_RS04715	COG3842	ATPase activity
PS273GM_RS04735	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PS273GM_RS04760	COG0330	HflC and HflK could
PS273GM_RS04820	COG1595	DNA-templated transcription, initiation
PS273GM_RS04825	COG3712	iron ion homeostasis
PS273GM_RS04830	COG4774	siderophore transport
PS273GM_RS04850	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PS273GM_RS04865	COG0513	Belongs to the DEAD box helicase family
PS273GM_RS04875	COG1289	transmembrane transporter activity
PS273GM_RS04885	COG2081	HI0933 family
PS273GM_RS04925	COG0191	fructose-bisphosphate aldolase activity
PS273GM_RS04940	COG0126	phosphoglycerate kinase activity
PS273GM_RS04945	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PS273GM_RS04950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PS273GM_RS04955	COG0583	DNA-binding transcription factor activity
PS273GM_RS04960	COG2175	clavaminate synthase activity
PS273GM_RS04970	COG2890	protein-(glutamine-N5) methyltransferase activity
PS273GM_RS04975	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PS273GM_RS04980	COG0842	Transport permease protein
PS273GM_RS04985	COG1131	(ABC) transporter
PS273GM_RS04990	COG0633	Ferredoxin
PS273GM_RS04990	COG0543	2 iron, 2 sulfur cluster binding
PS273GM_RS04995	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PS273GM_RS05020	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PS273GM_RS05025	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PS273GM_RS05030	COG0513	Belongs to the DEAD box helicase family
PS273GM_RS05045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PS273GM_RS05050	COG2353	YceI-like domain
PS273GM_RS05055	COG3038	cytochrome b561
PS273GM_RS05065	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PS273GM_RS05080	COG0784	Response regulator, receiver
PS273GM_RS05080	COG2198	Histidine kinase
PS273GM_RS05080	COG0643	Histidine kinase
PS273GM_RS05120	COG1678	Uncharacterized ACR, COG1678
PS273GM_RS05130	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PS273GM_RS05135	COG0540	Belongs to the ATCase OTCase family
PS273GM_RS05190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PS273GM_RS05195	COG2813	Specifically methylates the guanine in position
PS273GM_RS05195	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PS273GM_RS05210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PS273GM_RS05250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PS273GM_RS05255	COG2022	thiamine diphosphate biosynthetic process
PS273GM_RS05265	COG2363	Small membrane protein
PS273GM_RS05270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PS273GM_RS05285	COG2177	Part of the ABC transporter FtsEX involved in
PS273GM_RS05290	COG2884	Cell division ATP-binding protein ftsE
PS273GM_RS05295	COG0552	protein localization to endoplasmic reticulum
PS273GM_RS05300	COG0612	Peptidase, M16
PS273GM_RS05305	COG0612	Peptidase, M16
PS273GM_RS05310	COG0742	ribosomal rna small subunit methyltransferase
PS273GM_RS05335	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PS273GM_RS05345	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PS273GM_RS05355	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PS273GM_RS05365	COG0693	protein deglycase activity
PS273GM_RS05380	COG0129	dihydroxy-acid dehydratase activity
PS273GM_RS05390	COG2233	PERMEase
PS273GM_RS05395	COG0579	oxidoreductase
PS273GM_RS05415	COG0584	glycerophosphoryl diester phosphodiesterase
PS273GM_RS05420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PS273GM_RS05425	COG3181	Tripartite tricarboxylate transporter family receptor
PS273GM_RS05445	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PS273GM_RS05465	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PS273GM_RS05470	COG0581	inorganic phosphate transmembrane transporter activity
PS273GM_RS05490	COG2203	Gaf domain
PS273GM_RS05490	COG3706	GGDEF domain
PS273GM_RS05490	COG4251	negative regulation of phosphorylation
PS273GM_RS05490	COG5001	Diguanylate cyclase
PS273GM_RS05510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PS273GM_RS05525	COG1074	ATP-dependent DNA helicase activity
PS273GM_RS05530	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PS273GM_RS05540	COG1283	sodium-dependent phosphate transmembrane transporter activity
PS273GM_RS05550	COG2358	TRAP transporter, solute receptor (TAXI family
PS273GM_RS05555	COG0840	transmembrane signaling receptor activity
PS273GM_RS05560	COG4251	negative regulation of phosphorylation
PS273GM_RS05560	COG2203	Gaf domain
PS273GM_RS05560	COG3706	GGDEF domain
PS273GM_RS05560	COG5001	Diguanylate cyclase
PS273GM_RS05565	COG0642	Histidine kinase
PS273GM_RS05595	COG3180	Ammonia monooxygenase
PS273GM_RS05600	COG0700	Nucleoside recognition
PS273GM_RS05615	COG2204	response regulator
PS273GM_RS05620	COG5002	protein histidine kinase activity
PS273GM_RS05630	COG3023	N-Acetylmuramoyl-L-alanine amidase
PS273GM_RS05660	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PS273GM_RS05660	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PS273GM_RS05675	COG1178	ABC-type Fe3 transport system permease component
PS273GM_RS05685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PS273GM_RS05690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PS273GM_RS05695	COG0006	proline dipeptidase activity
PS273GM_RS05700	COG3079	Belongs to the UPF0149 family
PS273GM_RS05720	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PS273GM_RS05740	COG0604	alcohol dehydrogenase
PS273GM_RS05745	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PS273GM_RS05760	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PS273GM_RS05765	COG4942	peptidase
PS273GM_RS05770	COG0793	Belongs to the peptidase S41A family
PS273GM_RS05775	COG2861	carbohydrate metabolic process
PS273GM_RS05795	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PS273GM_RS05810	COG0131	Imidazoleglycerol-phosphate dehydratase
PS273GM_RS05825	COG1194	a g-specific adenine glycosylase
PS273GM_RS05830	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
PS273GM_RS05870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PS273GM_RS05880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PS273GM_RS05895	COG0676	glucose-6-phosphate 1-epimerase activity
PS273GM_RS05935	COG0583	DNA-binding transcription factor activity
PS273GM_RS05940	COG1027	Aspartate ammonia-lyase
PS273GM_RS05955	COG1115	amino acid carrier protein
PS273GM_RS05960	COG0252	asparaginase activity
PS273GM_RS05965	COG5002	protein histidine kinase activity
PS273GM_RS05965	COG2198	Histidine kinase
PS273GM_RS05965	COG0784	Response regulator, receiver
PS273GM_RS05970	COG1218	3'(2'),5'-bisphosphate nucleotidase
PS273GM_RS05975	COG0494	nUDIX hydrolase
PS273GM_RS05980	COG1011	Hydrolase
PS273GM_RS05985	COG0784	Response regulator, receiver
PS273GM_RS05985	COG4191	Histidine kinase
PS273GM_RS05990	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PS273GM_RS06000	COG3383	formate dehydrogenase (NAD+) activity
PS273GM_RS06015	COG1910	domain protein
PS273GM_RS06025	COG0824	Thioesterase
PS273GM_RS06030	COG1454	alcohol dehydrogenase
PS273GM_RS06035	COG1960	acyl-CoA dehydrogenase activity
PS273GM_RS06040	COG1024	Enoyl-CoA hydratase
PS273GM_RS06040	COG1250	3-hydroxyacyl-CoA dehydrogenase
PS273GM_RS06055	COG1278	Cold shock
PS273GM_RS06075	COG0667	Aldo Keto reductase
PS273GM_RS06095	COG0514	ATP-dependent DNA helicase (RecQ)
PS273GM_RS06105	COG0778	Nitroreductase
PS273GM_RS06110	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PS273GM_RS06120	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PS273GM_RS06125	COG4067	protein conserved in archaea
PS273GM_RS06125	COG0189	ligase activity
PS273GM_RS06130	COG0189	ligase activity
PS273GM_RS06145	COG2183	response to ionizing radiation
PS273GM_RS06155	COG2918	glutathione biosynthetic process
PS273GM_RS06175	COG0306	phosphate transporter
PS273GM_RS06180	COG1392	Phosphate transport regulator
PS273GM_RS06190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PS273GM_RS06200	COG2989	Protein conserved in bacteria
PS273GM_RS06215	COG1764	response to oxidative stress
PS273GM_RS06220	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PS273GM_RS06255	COG1253	flavin adenine dinucleotide binding
PS273GM_RS06275	COG0586	Pfam SNARE associated Golgi protein
PS273GM_RS06295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PS273GM_RS06300	COG2010	Cytochrome c
PS273GM_RS06300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PS273GM_RS06315	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PS273GM_RS06320	COG1127	ABC transporter
PS273GM_RS06325	COG3218	ABC-type transport auxiliary lipoprotein component
PS273GM_RS06325	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PS273GM_RS06335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PS273GM_RS06340	COG0842	Transport permease protein
PS273GM_RS06340	COG1129	ABC transporter
PS273GM_RS06345	COG0842	Transport permease protein
PS273GM_RS06420	COG1177	transmembrane transport
PS273GM_RS06425	COG1176	ABC-type spermidine putrescine transport system, permease component I
PS273GM_RS06430	COG3842	ATPase activity
PS273GM_RS06450	COG0174	glutamine synthetase
PS273GM_RS06455	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PS273GM_RS06460	COG0174	glutamine synthetase
PS273GM_RS06480	COG2957	Belongs to the agmatine deiminase family
PS273GM_RS06490	COG2199	diguanylate cyclase activity
PS273GM_RS06500	COG4191	Histidine kinase
PS273GM_RS06505	COG2201	protein-glutamate methylesterase activity
PS273GM_RS06510	COG5002	protein histidine kinase activity
PS273GM_RS06515	COG0745	RESPONSE REGULATOR receiver
PS273GM_RS06525	COG5002	protein histidine kinase activity
PS273GM_RS06530	COG0745	RESPONSE REGULATOR receiver
PS273GM_RS06550	COG1012	belongs to the aldehyde dehydrogenase family
PS273GM_RS06555	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PS273GM_RS06560	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PS273GM_RS06565	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PS273GM_RS06590	COG1960	acyl-CoA dehydrogenase activity
PS273GM_RS06595	COG1024	Enoyl-CoA hydratase
PS273GM_RS06595	COG1250	3-hydroxyacyl-CoA dehydrogenase
PS273GM_RS06610	COG2963	transposase activity
PS273GM_RS06615	COG2801	Transposase and inactivated derivatives
PS273GM_RS06690	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PS273GM_RS06690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PS273GM_RS06760	COG2433	Pfam Transposase IS66
PS273GM_RS06790	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PS273GM_RS06830	COG4221	oxidoreductase activity
PS273GM_RS06835	COG2433	Pfam Transposase IS66
PS273GM_RS06870	COG2132	Multicopper oxidase
PS273GM_RS06895	COG3258	Cytochrome c
PS273GM_RS06900	COG2863	cytochrome
PS273GM_RS06910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PS273GM_RS06925	COG0642	Histidine kinase
PS273GM_RS06930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PS273GM_RS06950	COG0640	Transcriptional regulator
PS273GM_RS07020	COG0583	DNA-binding transcription factor activity
PS273GM_RS07025	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS07030	COG0640	Transcriptional regulator
PS273GM_RS07035	COG1902	pentaerythritol trinitrate reductase activity
PS273GM_RS07075	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PS273GM_RS07095	COG3052	prosthetic group binding
PS273GM_RS07100	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
PS273GM_RS07110	COG1238	metal cluster binding
PS273GM_RS07130	COG2358	TRAP transporter, solute receptor (TAXI family
PS273GM_RS07175	COG0523	cobalamin synthesis protein
PS273GM_RS07190	COG4251	negative regulation of phosphorylation
PS273GM_RS07195	COG0784	Response regulator, receiver
PS273GM_RS07200	COG4191	Histidine kinase
PS273GM_RS07200	COG0784	Response regulator, receiver
PS273GM_RS07210	COG0483	inositol monophosphate 1-phosphatase activity
PS273GM_RS07225	COG4974	Belongs to the 'phage' integrase family
PS273GM_RS07265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PS273GM_RS07310	COG3642	lipopolysaccharide core region biosynthetic process
PS273GM_RS07370	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PS273GM_RS07375	COG1349	DNA-binding transcription factor activity
PS273GM_RS07380	COG0840	transmembrane signaling receptor activity
PS273GM_RS07385	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PS273GM_RS07390	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PS273GM_RS07395	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PS273GM_RS07400	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PS273GM_RS07405	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PS273GM_RS07410	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PS273GM_RS07415	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PS273GM_RS07425	COG0356	it plays a direct role in the translocation of protons across the membrane
PS273GM_RS07435	COG1475	DNA binding
PS273GM_RS07440	COG1192	Involved in chromosome partitioning
PS273GM_RS07445	COG0357	Ribosomal RNA small subunit methyltransferase G
PS273GM_RS07450	COG0445	tRNA wobble uridine modification
PS273GM_RS07455	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PS273GM_RS07460	COG0706	membrane insertase activity
PS273GM_RS07465	COG0594	ribonuclease P activity
PS273GM_RS07470	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PS273GM_RS07480	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PS273GM_RS07490	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
PS273GM_RS07500	COG3039	Transposase
PS273GM_RS07505	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
PS273GM_RS07515	COG0464	growth
PS273GM_RS07675	COG0751	glycine-tRNA ligase activity
PS273GM_RS07680	COG0752	glycyl-tRNA synthetase alpha subunit
PS273GM_RS07685	COG2818	Glycosylase
PS273GM_RS07705	COG1126	abc transporter atp-binding protein
PS273GM_RS07710	COG0765	amino acid transport
PS273GM_RS07715	COG0765	amino acid transport
PS273GM_RS07720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PS273GM_RS07725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PS273GM_RS07730	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PS273GM_RS07735	COG0569	domain protein
PS273GM_RS07740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PS273GM_RS07745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PS273GM_RS07750	COG0242	peptide deformylase activity
PS273GM_RS07755	COG1652	LysM domain
PS273GM_RS07760	COG0758	DNA mediated transformation
PS273GM_RS07765	COG0009	L-threonylcarbamoyladenylate synthase
PS273GM_RS07775	COG0408	coproporphyrinogen oxidase activity
PS273GM_RS07780	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PS273GM_RS07795	COG1686	Belongs to the peptidase S11 family
PS273GM_RS07825	COG0784	Response regulator, receiver
PS273GM_RS07825	COG4191	Histidine kinase
PS273GM_RS07845	COG0604	alcohol dehydrogenase
PS273GM_RS07845	COG3321	synthase
PS273GM_RS07905	COG1132	(ABC) transporter
PS273GM_RS07915	COG3340	Belongs to the peptidase S51 family
PS273GM_RS07920	COG1943	Transposase
PS273GM_RS07925	COG5339	Protein conserved in bacteria
PS273GM_RS07935	COG1525	nuclease
PS273GM_RS07935	COG4085	toxin activity
PS273GM_RS07935	COG0737	Belongs to the 5'-nucleotidase family
PS273GM_RS07940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PS273GM_RS07945	COG0569	domain protein
PS273GM_RS07960	COG0625	glutathione transferase activity
PS273GM_RS07970	COG0159	tryptophan synthase activity
PS273GM_RS08000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PS273GM_RS08020	COG1132	(ABC) transporter
PS273GM_RS08030	COG3360	Dodecin
PS273GM_RS08040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PS273GM_RS08085	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PS273GM_RS08090	COG2207	Transcriptional regulator
PS273GM_RS08100	COG0339	signal peptide processing
PS273GM_RS08130	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PS273GM_RS08135	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PS273GM_RS08165	COG0109	protoheme IX farnesyltransferase activity
PS273GM_RS08180	COG2011	ABC-type metal ion transport system permease component
PS273GM_RS08195	COG1451	nucleotide metabolic process
PS273GM_RS08200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PS273GM_RS08205	COG1121	(ABC) transporter
PS273GM_RS08210	COG0735	belongs to the Fur family
PS273GM_RS08215	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
PS273GM_RS08230	COG1611	Belongs to the LOG family
PS273GM_RS08340	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PS273GM_RS08345	COG0583	DNA-binding transcription factor activity
PS273GM_RS08395	COG2271	Major facilitator Superfamily
PS273GM_RS08410	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PS273GM_RS08420	COG1987	bacterial-type flagellum assembly
PS273GM_RS08495	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PS273GM_RS08520	COG1191	sigma factor activity
PS273GM_RS08525	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PS273GM_RS08545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PS273GM_RS08565	COG1815	bacterial-type flagellum-dependent cell motility
PS273GM_RS08570	COG1558	bacterial-type flagellum-dependent cell motility
PS273GM_RS08575	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
PS273GM_RS08585	COG4787	bacterial-type flagellum-dependent cell motility
PS273GM_RS08590	COG4786	Flagellar basal body rod
PS273GM_RS08595	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PS273GM_RS08600	COG1706	bacterial-type flagellum-dependent cell motility
PS273GM_RS08605	COG0741	lytic transglycosylase activity
PS273GM_RS08610	COG4786	Flagellar basal body rod
PS273GM_RS08610	COG1256	bacterial-type flagellum assembly
PS273GM_RS08625	COG2706	6-phosphogluconolactonase activity
PS273GM_RS08635	COG4191	Histidine kinase
PS273GM_RS08635	COG0784	Response regulator, receiver
PS273GM_RS08650	COG3795	YCII-related domain
PS273GM_RS08655	COG4941	Belongs to the sigma-70 factor family
PS273GM_RS08660	COG2204	response regulator
PS273GM_RS08675	COG0659	secondary active sulfate transmembrane transporter activity
PS273GM_RS08680	COG0589	response to stress
PS273GM_RS08685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PS273GM_RS08700	COG3276	selenocysteine insertion sequence binding
PS273GM_RS08705	COG1921	L-seryl-tRNASec selenium transferase activity
PS273GM_RS08715	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PS273GM_RS08720	COG0210	DNA helicase
PS273GM_RS08730	COG0826	peptidase U32
PS273GM_RS08745	COG0527	aspartate kinase activity
PS273GM_RS08750	COG5285	phytanoyl-CoA dioxygenase
PS273GM_RS08755	COG1917	Cupin 2, conserved barrel domain protein
PS273GM_RS08760	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PS273GM_RS08770	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PS273GM_RS08775	COG1737	Transcriptional regulator
PS273GM_RS08775	COG0837	glucose binding
PS273GM_RS08785	COG0583	DNA-binding transcription factor activity
PS273GM_RS08790	COG0439	Biotin carboxylase
PS273GM_RS08795	COG5016	pyruvate
PS273GM_RS08795	COG0511	ligase activity, forming carbon-carbon bonds
PS273GM_RS08815	COG2066	Belongs to the glutaminase family
PS273GM_RS08840	COG0058	SHG alpha-glucan phosphorylase activity
PS273GM_RS08845	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PS273GM_RS08875	COG1490	D-aminoacyl-tRNA deacylase activity
PS273GM_RS08895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PS273GM_RS08900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PS273GM_RS08905	COG0140	phosphoribosyl-ATP diphosphatase activity
PS273GM_RS08910	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PS273GM_RS08915	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PS273GM_RS08925	COG2226	methyltransferase
PS273GM_RS08935	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PS273GM_RS08960	COG3852	Histidine kinase
PS273GM_RS08980	COG0301	tRNA thio-modification
PS273GM_RS08980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PS273GM_RS08985	COG1217	gtp-binding protein TYPA
PS273GM_RS09000	COG2010	Cytochrome c
PS273GM_RS09015	COG2815	serine threonine protein kinase
PS273GM_RS09015	COG0515	serine threonine protein kinase
PS273GM_RS09020	COG0631	protein serine/threonine phosphatase activity
PS273GM_RS09055	COG3675	Pfam Lipase (class 3)
PS273GM_RS09160	COG2819	hydrolase of the alpha beta superfamily
PS273GM_RS09175	COG2207	Transcriptional regulator
PS273GM_RS09190	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
PS273GM_RS09200	COG4807	Protein conserved in bacteria
PS273GM_RS09215	COG2204	response regulator
PS273GM_RS09220	COG5001	Diguanylate cyclase
PS273GM_RS09225	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PS273GM_RS09245	COG0351	phosphomethylpyrimidine kinase
PS273GM_RS09265	COG1320	monovalent cation:proton antiporter activity
PS273GM_RS09280	COG0651	ATP synthesis coupled electron transport
PS273GM_RS09285	COG0651	ATP synthesis coupled electron transport
PS273GM_RS09290	COG0651	ATP synthesis coupled electron transport
PS273GM_RS09295	COG0840	transmembrane signaling receptor activity
PS273GM_RS09305	COG3647	Membrane
PS273GM_RS09330	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS09360	COG2197	response regulator
PS273GM_RS09375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PS273GM_RS09380	COG0277	FAD linked oxidase domain protein
PS273GM_RS09385	COG0179	Fumarylacetoacetate (FAA) hydrolase
PS273GM_RS09400	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PS273GM_RS09405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PS273GM_RS09420	COG0494	nUDIX hydrolase
PS273GM_RS09425	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
PS273GM_RS09435	COG0730	response to heat
PS273GM_RS09440	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PS273GM_RS09445	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PS273GM_RS09450	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PS273GM_RS09455	COG1192	Involved in chromosome partitioning
PS273GM_RS09470	COG0739	heme binding
PS273GM_RS09475	COG1253	flavin adenine dinucleotide binding
PS273GM_RS09490	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PS273GM_RS09510	COG2186	Transcriptional regulator
PS273GM_RS09515	COG0277	FAD linked oxidase domain protein
PS273GM_RS09520	COG0277	FAD linked oxidase domain protein
PS273GM_RS09525	COG0247	lactate metabolic process
PS273GM_RS09530	COG3193	protein, possibly involved in utilization of glycolate and propanediol
PS273GM_RS09535	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PS273GM_RS09540	COG1620	l-lactate permease
PS273GM_RS09575	COG0583	DNA-binding transcription factor activity
PS273GM_RS09580	COG1960	acyl-CoA dehydrogenase activity
PS273GM_RS09585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PS273GM_RS09590	COG1704	LemA family
PS273GM_RS09595	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PS273GM_RS09605	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PS273GM_RS09620	COG2080	2 iron, 2 sulfur cluster binding
PS273GM_RS09630	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PS273GM_RS09645	COG2885	chlorophyll binding
PS273GM_RS09650	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
PS273GM_RS09660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PS273GM_RS09665	COG1758	RNA polymerase activity
PS273GM_RS09675	COG1561	YicC-like family, N-terminal region
PS273GM_RS09680	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PS273GM_RS09690	COG0708	Exodeoxyribonuclease III
PS273GM_RS09695	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PS273GM_RS09705	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PS273GM_RS09715	COG0756	dUTP diphosphatase activity
PS273GM_RS09720	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PS273GM_RS09725	COG2003	Belongs to the UPF0758 family
PS273GM_RS09755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PS273GM_RS09770	COG2050	protein possibly involved in aromatic compounds catabolism
PS273GM_RS09775	COG1250	3-hydroxyacyl-CoA dehydrogenase
PS273GM_RS09795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PS273GM_RS09800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PS273GM_RS09810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PS273GM_RS09815	COG0251	oxidation-reduction process
PS273GM_RS09835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PS273GM_RS09850	COG0366	Alpha amylase catalytic
PS273GM_RS09865	COG1454	alcohol dehydrogenase
PS273GM_RS09875	COG1414	Transcriptional regulator
PS273GM_RS09890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PS273GM_RS09895	COG0606	chelatase, subunit chli
PS273GM_RS09950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PS273GM_RS09960	COG0789	Transcriptional regulator
PS273GM_RS09990	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
PS273GM_RS10015	COG2124	cytochrome p450
PS273GM_RS10030	COG3039	Transposase
PS273GM_RS10035	COG3039	Transposase
PS273GM_RS10040	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PS273GM_RS10055	COG0789	Transcriptional regulator
PS273GM_RS10070	COG4772	TonB-dependent receptor
PS273GM_RS10085	COG4974	Belongs to the 'phage' integrase family
PS273GM_RS10105	COG0583	DNA-binding transcription factor activity
PS273GM_RS10110	COG2855	membrane
PS273GM_RS10115	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PS273GM_RS10120	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
PS273GM_RS10150	COG2010	Cytochrome c
PS273GM_RS10185	COG3039	Transposase
PS273GM_RS10215	COG2433	Pfam Transposase IS66
PS273GM_RS10275	COG2960	long-chain fatty acid transporting porin activity
PS273GM_RS10280	COG0347	Belongs to the P(II) protein family
PS273GM_RS10285	COG0004	ammonium transporteR
PS273GM_RS10290	COG0004	ammonium transporteR
PS273GM_RS10310	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PS273GM_RS10320	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PS273GM_RS10335	COG1965	Belongs to the frataxin family
PS273GM_RS10340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PS273GM_RS10360	COG0598	Magnesium transport protein CorA
PS273GM_RS10375	COG0165	Argininosuccinate lyase
PS273GM_RS10385	COG3275	phosphorelay sensor kinase activity
PS273GM_RS10415	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PS273GM_RS10435	COG0488	(ABC) transporter
PS273GM_RS10445	COG0861	Integral membrane protein TerC family
PS273GM_RS10455	COG1671	Belongs to the UPF0178 family
PS273GM_RS10460	COG2050	protein possibly involved in aromatic compounds catabolism
PS273GM_RS10465	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
PS273GM_RS10475	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PS273GM_RS10495	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PS273GM_RS10510	COG0018	arginyl-trna synthetase
PS273GM_RS10515	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PS273GM_RS10520	COG0254	rRNA binding
PS273GM_RS10530	COG0281	malic enzyme
PS273GM_RS10565	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PS273GM_RS10570	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PS273GM_RS10580	COG0067	glutamate synthase
PS273GM_RS10580	COG0069	glutamate synthase activity
PS273GM_RS10580	COG0070	glutamate synthase
PS273GM_RS10585	COG0493	'glutamate synthase
PS273GM_RS10610	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS10620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PS273GM_RS10650	COG2986	histidine ammonia-lyase
PS273GM_RS10675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PS273GM_RS10680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PS273GM_RS10695	COG3118	belongs to the thioredoxin family
PS273GM_RS10700	COG2873	o-acetylhomoserine
PS273GM_RS10705	COG0471	metal ion transport
PS273GM_RS10705	COG3273	potassium ion transport
PS273GM_RS10715	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PS273GM_RS10720	COG0358	DNA primase activity
PS273GM_RS10725	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PS273GM_RS10730	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PS273GM_RS10735	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PS273GM_RS10740	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PS273GM_RS10755	COG2719	SpoVR family
PS273GM_RS10760	COG2718	Belongs to the UPF0229 family
PS273GM_RS10765	COG2766	serine protein kinase
PS273GM_RS10770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PS273GM_RS10775	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PS273GM_RS10780	COG2967	ApaG domain
PS273GM_RS10785	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PS273GM_RS10790	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PS273GM_RS10795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PS273GM_RS10800	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PS273GM_RS10805	COG3178	'Phosphotransferase
PS273GM_RS10810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PS273GM_RS10830	COG2197	response regulator
PS273GM_RS10835	COG3842	ATPase activity
PS273GM_RS10845	COG1176	ABC-type spermidine putrescine transport system, permease component I
PS273GM_RS10860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PS273GM_RS10865	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PS273GM_RS10870	COG0546	phosphoglycolate phosphatase activity
PS273GM_RS10885	COG0512	Glutamine amidotransferase of anthranilate synthase
PS273GM_RS10890	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PS273GM_RS10895	COG0134	indole-3-glycerol-phosphate synthase activity
PS273GM_RS10905	COG1765	OsmC-like protein
PS273GM_RS10915	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
PS273GM_RS10920	COG0537	adenosine 5'-monophosphoramidase activity
PS273GM_RS10925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PS273GM_RS10935	COG2070	2-Nitropropane dioxygenase
PS273GM_RS10940	COG1981	membrane
PS273GM_RS10945	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PS273GM_RS10950	COG0316	Belongs to the HesB IscA family
PS273GM_RS10955	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PS273GM_RS10960	COG0739	heme binding
PS273GM_RS10965	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PS273GM_RS10995	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
PS273GM_RS10995	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
PS273GM_RS11000	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PS273GM_RS11050	COG0081	regulation of translation
PS273GM_RS11060	COG0222	ribosome binding
PS273GM_RS11065	COG0085	RNA polymerase activity
PS273GM_RS11070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PS273GM_RS11075	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PS273GM_RS11080	COG0049	tRNA binding
PS273GM_RS11085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PS273GM_RS11095	COG0051	transcription antitermination factor activity, RNA binding
PS273GM_RS11100	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PS273GM_RS11105	COG0088	Forms part of the polypeptide exit tunnel
PS273GM_RS11110	COG0089	rRNA binding
PS273GM_RS11115	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PS273GM_RS11120	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PS273GM_RS11125	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PS273GM_RS11130	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PS273GM_RS11135	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PS273GM_RS11140	COG0255	Belongs to the universal ribosomal protein uL29 family
PS273GM_RS11145	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PS273GM_RS11150	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PS273GM_RS11155	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PS273GM_RS11160	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PS273GM_RS11165	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PS273GM_RS11170	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PS273GM_RS11175	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PS273GM_RS11185	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PS273GM_RS11190	COG1841	ribosomal large subunit assembly
PS273GM_RS11195	COG0200	Binds to the 23S rRNA
PS273GM_RS11205	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PS273GM_RS11210	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PS273GM_RS11215	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PS273GM_RS11220	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PS273GM_RS11225	COG0202	RNA polymerase activity
PS273GM_RS11230	COG0203	ribosomal protein L17
PS273GM_RS11240	COG2814	Major facilitator Superfamily
PS273GM_RS11260	COG3047	cAMP biosynthetic process
PS273GM_RS11270	COG0811	peptide transport
PS273GM_RS11275	COG0811	peptide transport
PS273GM_RS11280	COG0848	biopolymer transport protein
PS273GM_RS11320	COG2321	neutral zinc metallopeptidase
PS273GM_RS11340	COG2197	response regulator
PS273GM_RS11360	COG2223	nitrite transmembrane transporter activity
PS273GM_RS11365	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PS273GM_RS11370	COG1140	nitrate reductase beta subunit
PS273GM_RS11375	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PS273GM_RS11380	COG2181	nitrate reductase activity
PS273GM_RS11395	COG0521	Mo-molybdopterin cofactor biosynthetic process
PS273GM_RS11400	COG0303	'Molybdopterin
PS273GM_RS11405	COG3038	cytochrome b561
PS273GM_RS11410	COG0642	Histidine kinase
PS273GM_RS11460	COG1368	sulfuric ester hydrolase activity
PS273GM_RS11465	COG0745	RESPONSE REGULATOR receiver
PS273GM_RS11480	COG3642	lipopolysaccharide core region biosynthetic process
PS273GM_RS11510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PS273GM_RS11515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PS273GM_RS11520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PS273GM_RS11525	COG2252	PERMEase
PS273GM_RS11535	COG2080	2 iron, 2 sulfur cluster binding
PS273GM_RS11540	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PS273GM_RS11545	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PS273GM_RS11560	COG0789	Transcriptional regulator
PS273GM_RS11565	COG2813	Specifically methylates the guanine in position
PS273GM_RS11580	COG1012	belongs to the aldehyde dehydrogenase family
PS273GM_RS11600	COG4176	ABC-type proline glycine betaine transport system permease component
PS273GM_RS11605	COG4175	Glycine betaine
PS273GM_RS11610	COG1760	l-serine dehydratase
PS273GM_RS11630	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PS273GM_RS11635	COG2181	nitrate reductase activity
PS273GM_RS11635	COG0247	lactate metabolic process
PS273GM_RS11640	COG0446	pyridine nucleotide-disulphide oxidoreductase
PS273GM_RS11640	COG1902	pentaerythritol trinitrate reductase activity
PS273GM_RS11660	COG1063	alcohol dehydrogenase
PS273GM_RS11695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PS273GM_RS11695	COG1017	nitric oxide dioxygenase activity
PS273GM_RS11725	COG0488	(ABC) transporter
PS273GM_RS11770	COG2433	Pfam Transposase IS66
PS273GM_RS11800	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PS273GM_RS11815	COG2020	methyltransferase activity
PS273GM_RS11840	COG1970	mechanosensitive ion channel activity
PS273GM_RS11850	COG0714	Associated with various cellular activities
PS273GM_RS11855	COG3256	nitric oxide reductase
PS273GM_RS11860	COG2010	Cytochrome c
PS273GM_RS11875	COG1067	ATP-dependent peptidase activity
PS273GM_RS11885	COG2862	Uncharacterized protein family, UPF0114
PS273GM_RS11895	COG0545	Peptidyl-prolyl cis-trans isomerase
PS273GM_RS11905	COG0142	geranyltranstransferase activity
PS273GM_RS11910	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PS273GM_RS11915	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PS273GM_RS11920	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PS273GM_RS11925	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PS273GM_RS11930	COG3045	CreA protein
PS273GM_RS11935	COG0268	Binds directly to 16S ribosomal RNA
PS273GM_RS11945	COG0196	riboflavin kinase activity
PS273GM_RS11950	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PS273GM_RS11955	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PS273GM_RS11960	COG1047	Peptidyl-prolyl cis-trans
PS273GM_RS11965	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PS273GM_RS12005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PS273GM_RS12010	COG0023	Translation Initiation Factor
PS273GM_RS12015	COG1166	arginine decarboxylase activity
PS273GM_RS12020	COG2824	Alkylphosphonate utilization operon protein PhnA
PS273GM_RS12025	COG1607	acyl-coa hydrolase
PS273GM_RS12040	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
PS273GM_RS12055	COG0420	3'-5' exonuclease activity
PS273GM_RS12120	COG0028	Belongs to the TPP enzyme family
PS273GM_RS12125	COG0564	pseudouridine synthase activity
PS273GM_RS12145	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
PS273GM_RS12150	COG3639	organic phosphonate transmembrane transporter activity
PS273GM_RS12155	COG2188	Transcriptional regulator
PS273GM_RS12160	COG3624	Phosphonate C-P lyase system protein PhnG
PS273GM_RS12165	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
PS273GM_RS12170	COG3626	phosphonate metabolism
PS273GM_RS12175	COG3627	carbon phosphorus lyase activity
PS273GM_RS12180	COG4107	phosphonate C-P lyase system protein PhnK
PS273GM_RS12185	COG4778	phosphonate C-P lyase system protein PhnL
PS273GM_RS12190	COG3454	Phosphonate metabolism
PS273GM_RS12200	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PS273GM_RS12210	COG1522	sequence-specific DNA binding
PS273GM_RS12225	COG0733	neurotransmitter:sodium symporter activity
PS273GM_RS12230	COG0625	glutathione transferase activity
PS273GM_RS12235	COG0733	neurotransmitter:sodium symporter activity
PS273GM_RS12265	COG2154	pterin-4-alpha-carbinolamine dehydratase
PS273GM_RS12285	COG1760	l-serine dehydratase
PS273GM_RS12300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PS273GM_RS12315	COG3189	MarR family transcriptional regulator
PS273GM_RS12330	COG1960	acyl-CoA dehydrogenase activity
PS273GM_RS12335	COG3901	Regulator of nitric oxide reductase transcription
PS273GM_RS12335	COG0348	domain, Protein
PS273GM_RS12340	COG4263	nitrous-oxide reductase activity
PS273GM_RS12355	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PS273GM_RS12375	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS12380	COG0840	transmembrane signaling receptor activity
PS273GM_RS12385	COG0517	IMP dehydrogenase activity
PS273GM_RS12405	COG1648	precorrin-2 dehydrogenase activity
PS273GM_RS12405	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PS273GM_RS12410	COG0535	radical SAM domain protein
PS273GM_RS12435	COG3391	amine dehydrogenase activity
PS273GM_RS12440	COG2010	Cytochrome c
PS273GM_RS12455	COG0714	Associated with various cellular activities
PS273GM_RS12460	COG1845	cytochrome c oxidase, subunit III
PS273GM_RS12475	COG2010	Cytochrome c
PS273GM_RS12480	COG3256	nitric oxide reductase
PS273GM_RS12490	COG3547	Transposase (IS116 IS110 IS902 family)
PS273GM_RS12500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PS273GM_RS12510	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
PS273GM_RS12515	COG3604	Transcriptional regulator
PS273GM_RS12525	COG0826	peptidase U32
PS273GM_RS12530	COG0826	peptidase U32
PS273GM_RS12535	COG3154	lipid carrier protein
PS273GM_RS12565	COG2153	protein acetylation
PS273GM_RS12590	COG2814	Major facilitator Superfamily
PS273GM_RS12615	COG0640	Transcriptional regulator
PS273GM_RS12635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PS273GM_RS12645	COG2863	cytochrome
PS273GM_RS12650	COG3258	Cytochrome c
PS273GM_RS12660	COG0583	DNA-binding transcription factor activity
PS273GM_RS12665	COG4221	oxidoreductase activity
PS273GM_RS12695	COG1902	pentaerythritol trinitrate reductase activity
PS273GM_RS12700	COG0640	Transcriptional regulator
PS273GM_RS12705	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PS273GM_RS12735	COG3385	transposase activity
PS273GM_RS12750	COG1902	pentaerythritol trinitrate reductase activity
PS273GM_RS12755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PS273GM_RS12775	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PS273GM_RS12775	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PS273GM_RS12780	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS12780	COG0604	alcohol dehydrogenase
PS273GM_RS12780	COG3321	synthase
PS273GM_RS12825	COG4221	oxidoreductase activity
PS273GM_RS12830	COG0583	DNA-binding transcription factor activity
PS273GM_RS12860	COG1238	metal cluster binding
PS273GM_RS12925	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PS273GM_RS12930	COG1061	Type III restriction enzyme res subunit
PS273GM_RS12935	COG4804	nuclease activity
PS273GM_RS12940	COG1002	Type II restriction enzyme, methylase subunits
PS273GM_RS12950	COG0582	viral genome integration into host DNA
PS273GM_RS12960	COG0582	viral genome integration into host DNA
PS273GM_RS13000	COG0629	single-stranded DNA binding
PS273GM_RS13010	COG3723	Recombinational DNA repair protein, rece pathway
PS273GM_RS13305	COG1620	l-lactate permease
PS273GM_RS13315	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PS273GM_RS13325	COG2914	Belongs to the UPF0125 (RnfH) family
PS273GM_RS13330	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PS273GM_RS13340	COG0497	DNA recombination
PS273GM_RS13345	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PS273GM_RS13350	COG0443	Heat shock 70 kDa protein
PS273GM_RS13355	COG0484	heat shock protein binding
PS273GM_RS13360	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PS273GM_RS13365	COG0505	Belongs to the CarA family
PS273GM_RS13375	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PS273GM_RS13390	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PS273GM_RS13400	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PS273GM_RS13405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PS273GM_RS13410	COG0149	triose-phosphate isomerase activity
PS273GM_RS13415	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PS273GM_RS13430	COG0779	Required for maturation of 30S ribosomal subunits
PS273GM_RS13435	COG0195	Participates in both transcription termination and antitermination
PS273GM_RS13440	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PS273GM_RS13445	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PS273GM_RS13450	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PS273GM_RS13455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PS273GM_RS13460	COG1185	polyribonucleotide nucleotidyltransferase activity
PS273GM_RS13500	COG0166	Belongs to the GPI family
PS273GM_RS13505	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PS273GM_RS13510	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PS273GM_RS13515	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PS273GM_RS13535	COG4191	Histidine kinase
PS273GM_RS13540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PS273GM_RS13545	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
PS273GM_RS13550	COG0436	Aminotransferase
PS273GM_RS13565	COG1285	pathogenesis
PS273GM_RS13585	COG3851	Histidine kinase
PS273GM_RS13590	COG0840	transmembrane signaling receptor activity
PS273GM_RS13595	COG0745	RESPONSE REGULATOR receiver
PS273GM_RS13605	COG2198	Histidine kinase
PS273GM_RS13605	COG0643	Histidine kinase
PS273GM_RS13610	COG0840	transmembrane signaling receptor activity
PS273GM_RS13615	COG0835	chemotaxis
PS273GM_RS13620	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PS273GM_RS13625	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
PS273GM_RS13630	COG2201	protein-glutamate methylesterase activity
PS273GM_RS13640	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS13645	COG0659	secondary active sulfate transmembrane transporter activity
PS273GM_RS13700	COG0501	Belongs to the peptidase M48B family
PS273GM_RS13710	COG2119	membrane
PS273GM_RS13715	COG2813	Specifically methylates the guanine in position
PS273GM_RS13720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PS273GM_RS13725	COG1280	lysine exporter protein (LysE YggA)
PS273GM_RS13730	COG0318	PFAM AMP-dependent synthetase and ligase
PS273GM_RS13735	COG2885	chlorophyll binding
PS273GM_RS13740	COG4999	Histidine kinase
PS273GM_RS13740	COG3437	response regulator, receiver
PS273GM_RS13740	COG2205	protein histidine kinase activity
PS273GM_RS13740	COG3850	Histidine kinase
PS273GM_RS13750	COG0204	Acyl-transferase
PS273GM_RS13760	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PS273GM_RS13770	COG0386	Belongs to the glutathione peroxidase family
PS273GM_RS13775	COG1309	transcriptional regulator
PS273GM_RS13790	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
PS273GM_RS13810	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PS273GM_RS13830	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
PS273GM_RS13855	COG0693	protein deglycase activity
PS273GM_RS13860	COG4628	conserved protein (DUF2132)
PS273GM_RS13905	COG0714	Associated with various cellular activities
PS273GM_RS13930	COG2925	Exonuclease
PS273GM_RS13940	COG0788	formyltetrahydrofolate deformylase activity
PS273GM_RS13950	COG0433	COG0433 Predicted ATPase
PS273GM_RS13965	COG3022	response to hydroperoxide
PS273GM_RS13970	COG1230	cation diffusion facilitator family transporter
PS273GM_RS13975	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PS273GM_RS13980	COG0315	cyclic pyranopterin monophosphate synthase activity
PS273GM_RS13985	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PS273GM_RS14000	COG3706	GGDEF domain
PS273GM_RS14005	COG0400	carboxylic ester hydrolase activity
PS273GM_RS14010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PS273GM_RS14015	COG4597	amino acid ABC transporter
PS273GM_RS14020	COG0765	amino acid transport
PS273GM_RS14025	COG1126	abc transporter atp-binding protein
PS273GM_RS14030	COG0047	phosphoribosylformylglycinamidine synthase activity
PS273GM_RS14030	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PS273GM_RS14040	COG1764	response to oxidative stress
PS273GM_RS14045	COG1846	Transcriptional regulator
PS273GM_RS14050	COG3034	peptidoglycan biosynthetic process
PS273GM_RS14070	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PS273GM_RS14075	COG4536	flavin adenine dinucleotide binding
PS273GM_RS14080	COG4137	Cytochrome C assembly protein
PS273GM_RS14085	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PS273GM_RS14090	COG0228	four-way junction DNA binding
PS273GM_RS14095	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PS273GM_RS14100	COG0336	Belongs to the RNA methyltransferase TrmD family
PS273GM_RS14105	COG0335	large ribosomal subunit rRNA binding
PS273GM_RS14120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PS273GM_RS14125	COG3791	Glutathione-dependent formaldehyde-activating
PS273GM_RS14140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PS273GM_RS14145	COG0418	dihydroorotase activity
PS273GM_RS14155	COG0137	argininosuccinate synthase activity
PS273GM_RS14170	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PS273GM_RS14180	COG4659	FMN binding
PS273GM_RS14185	COG4658	electron transport chain
PS273GM_RS14195	COG2878	Part of a membrane complex involved in electron transport
PS273GM_RS14200	COG4657	Part of a membrane complex involved in electron transport
PS273GM_RS14210	COG1024	Enoyl-CoA hydratase
PS273GM_RS14220	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PS273GM_RS14270	COG3086	response to oxidative stress
PS273GM_RS14275	COG0481	GTPase activity
PS273GM_RS14290	COG0571	ribonuclease III activity
PS273GM_RS14295	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PS273GM_RS14300	COG1381	Involved in DNA repair and RecF pathway recombination
PS273GM_RS14305	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PS273GM_RS14315	COG0583	DNA-binding transcription factor activity
PS273GM_RS14325	COG0500	methyltransferase
PS273GM_RS14330	COG2226	methyltransferase
PS273GM_RS14340	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PS273GM_RS14355	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PS273GM_RS14385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PS273GM_RS14425	COG0583	DNA-binding transcription factor activity
PS273GM_RS14435	COG0583	DNA-binding transcription factor activity
PS273GM_RS14495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PS273GM_RS14675	COG2826	transposase and inactivated derivatives, IS30 family
PS273GM_RS14700	COG1063	alcohol dehydrogenase
PS273GM_RS14800	COG2003	Belongs to the UPF0758 family
PS273GM_RS14865	COG4644	lycopene metabolic process
PS273GM_RS14880	COG3328	transposase activity
PS273GM_RS14890	COG0277	FAD linked oxidase domain protein
PS273GM_RS14895	COG0582	viral genome integration into host DNA
PS273GM_RS14910	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PS273GM_RS14910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PS273GM_RS14915	COG0489	protein tyrosine kinase activity
PS273GM_RS14920	COG1278	Cold shock
PS273GM_RS14925	COG0717	Belongs to the dCTP deaminase family
PS273GM_RS14940	COG0583	DNA-binding transcription factor activity
PS273GM_RS14960	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PS273GM_RS14980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PS273GM_RS14980	COG1017	nitric oxide dioxygenase activity
PS273GM_RS15005	COG2084	Dehydrogenase
PS273GM_RS15010	COG3622	Belongs to the hyi family
PS273GM_RS15015	COG3960	tartronate-semialdehyde synthase activity
PS273GM_RS15025	COG0708	Exodeoxyribonuclease III
PS273GM_RS15035	COG2199	diguanylate cyclase activity
PS273GM_RS15035	COG2200	EAL domain
PS273GM_RS15035	COG3287	FIST C domain
PS273GM_RS15055	COG3287	FIST C domain
PS273GM_RS15055	COG2200	EAL domain
PS273GM_RS15055	COG2199	diguanylate cyclase activity
PS273GM_RS15090	COG2207	Transcriptional regulator
PS273GM_RS15125	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
PS273GM_RS15180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PS273GM_RS15210	COG1462	curli production assembly transport component CsgG
PS273GM_RS15230	COG1280	lysine exporter protein (LysE YggA)
PS273GM_RS15240	COG0656	L-ascorbic acid biosynthetic process
PS273GM_RS15280	COG4993	Dehydrogenase
PS273GM_RS15285	COG2996	Protein conserved in bacteria
PS273GM_RS15300	COG0489	protein tyrosine kinase activity
PS273GM_RS15325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PS273GM_RS15345	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PS273GM_RS15350	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
PS273GM_RS15370	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PS273GM_RS15395	COG1944	ATP diphosphatase activity
PS273GM_RS15410	COG1295	ribonuclease BN
PS273GM_RS15435	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
PS273GM_RS15440	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PS273GM_RS15450	COG1546	Belongs to the CinA family
PS273GM_RS15455	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PS273GM_RS15460	COG2137	regulation of response to DNA damage stimulus
PS273GM_RS15470	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PS273GM_RS15475	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
PS273GM_RS15485	COG3148	PFAM DTW domain containing protein
PS273GM_RS15490	COG0697	spore germination
PS273GM_RS15500	COG0583	DNA-binding transcription factor activity
PS273GM_RS15510	COG3012	SEC-C Motif Domain Protein
PS273GM_RS15530	COG1199	ATP-dependent helicase activity
PS273GM_RS15545	COG0259	pyridoxamine-phosphate oxidase activity
PS273GM_RS15555	COG3133	Outer membrane lipoprotein
PS273GM_RS15560	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PS273GM_RS15560	COG2111	Na H antiporter
PS273GM_RS15565	COG1006	Multisubunit Na H antiporter MnhC subunit
PS273GM_RS15570	COG0651	ATP synthesis coupled electron transport
PS273GM_RS15580	COG2212	antiporter activity
PS273GM_RS15585	COG1320	monovalent cation:proton antiporter activity
PS273GM_RS15590	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PS273GM_RS15595	COG0024	Methionine aminopeptidase
PS273GM_RS15600	COG0052	Belongs to the universal ribosomal protein uS2 family
PS273GM_RS15605	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PS273GM_RS15610	COG0528	UMP kinase activity
PS273GM_RS15615	COG0233	cytoplasmic translational termination
PS273GM_RS15620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PS273GM_RS15630	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PS273GM_RS15655	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PS273GM_RS15660	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PS273GM_RS15665	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PS273GM_RS15670	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PS273GM_RS15680	COG0825	malonyl-CoA metabolic process
PS273GM_RS15685	COG0037	tRNA processing
PS273GM_RS15690	COG0504	CTP synthase activity
PS273GM_RS15695	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PS273GM_RS15700	COG0148	phosphopyruvate hydratase activity
PS273GM_RS15710	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PS273GM_RS15725	COG0583	DNA-binding transcription factor activity
PS273GM_RS15730	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PS273GM_RS15740	COG1902	pentaerythritol trinitrate reductase activity
PS273GM_RS15745	COG0640	Transcriptional regulator
PS273GM_RS15750	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PS273GM_RS15755	COG0585	pseudouridine synthase activity
PS273GM_RS15760	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PS273GM_RS15765	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PS273GM_RS15785	COG0494	nUDIX hydrolase
PS273GM_RS15810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PS273GM_RS15830	COG0217	transcriptional regulatory protein
PS273GM_RS15835	COG0697	spore germination
PS273GM_RS15840	COG0840	transmembrane signaling receptor activity
PS273GM_RS15850	COG2258	MOSC domain
PS273GM_RS15865	COG0004	ammonium transporteR
PS273GM_RS15885	COG1309	transcriptional regulator
PS273GM_RS15915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PS273GM_RS15925	COG1380	Effector of murein hydrolase LrgA
PS273GM_RS15930	COG1346	cytolysis
PS273GM_RS15935	COG0596	Alpha beta hydrolase
PS273GM_RS15945	COG0655	NAD(P)H dehydrogenase (quinone) activity
PS273GM_RS15955	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PS273GM_RS15960	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PS273GM_RS15975	COG1805	sodium ion transport
PS273GM_RS15990	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PS273GM_RS16000	COG1477	protein flavinylation
PS273GM_RS16010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PS273GM_RS16015	COG0584	glycerophosphoryl diester phosphodiesterase
PS273GM_RS16030	COG4591	ABC-type transport system involved in lipoprotein release permease component
PS273GM_RS16035	COG1136	(ABC) transporter
PS273GM_RS16050	COG0658	competence protein
PS273GM_RS16050	COG2333	competence protein COMEC
PS273GM_RS16055	COG0811	peptide transport
PS273GM_RS16065	COG1663	tetraacyldisaccharide 4'-kinase activity
PS273GM_RS16070	COG2835	tetraacyldisaccharide 4'-kinase activity
PS273GM_RS16075	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PS273GM_RS16080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PS273GM_RS16085	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PS273GM_RS16090	COG1530	ribonuclease E activity
PS273GM_RS16105	COG0546	phosphoglycolate phosphatase activity
PS273GM_RS16110	COG0616	signal peptide processing
PS273GM_RS16110	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PS273GM_RS16115	COG0424	maF-like protein
PS273GM_RS16120	COG1399	metal-binding, possibly nucleic acid-binding protein
PS273GM_RS16125	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PS273GM_RS16130	COG0416	fatty acid biosynthetic process
PS273GM_RS16145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PS273GM_RS16150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PS273GM_RS16160	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PS273GM_RS16165	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PS273GM_RS16180	COG0084	hydrolase, TatD family'
PS273GM_RS16185	COG1113	amino acid transport
PS273GM_RS16205	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
PS273GM_RS16230	COG2226	methyltransferase
PS273GM_RS16235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PS273GM_RS16240	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PS273GM_RS16245	COG2166	iron-sulfur cluster assembly
PS273GM_RS16250	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PS273GM_RS16255	COG2171	N-acyltransferase activity
PS273GM_RS16260	COG1393	Belongs to the ArsC family
PS273GM_RS16270	COG0436	Aminotransferase
PS273GM_RS16285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PS273GM_RS16290	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PS273GM_RS16300	COG0628	permease
PS273GM_RS16320	COG1393	Belongs to the ArsC family
PS273GM_RS16325	COG1295	ribonuclease BN
PS273GM_RS16330	COG3118	belongs to the thioredoxin family
PS273GM_RS16345	COG0442	prolyl-tRNA aminoacylation
PS273GM_RS16360	COG2900	Belongs to the SlyX family
PS273GM_RS16370	COG0783	Belongs to the Dps family
PS273GM_RS16375	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PS273GM_RS16385	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PS273GM_RS16390	COG0632	four-way junction helicase activity
PS273GM_RS16395	COG2255	four-way junction helicase activity
PS273GM_RS16400	COG0824	Thioesterase
PS273GM_RS16420	COG0823	Involved in the tonB-independent uptake of proteins
PS273GM_RS16425	COG2885	chlorophyll binding
PS273GM_RS16430	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PS273GM_RS16435	COG0602	queuosine metabolic process
PS273GM_RS16440	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PS273GM_RS16450	COG0427	acetyl-CoA hydrolase
PS273GM_RS16460	COG4783	chaperone-mediated protein folding
PS273GM_RS16465	COG0425	Belongs to the sulfur carrier protein TusA family
PS273GM_RS16475	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PS273GM_RS16485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PS273GM_RS16495	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PS273GM_RS16535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PS273GM_RS16545	COG2199	diguanylate cyclase activity
PS273GM_RS16545	COG2203	Gaf domain
PS273GM_RS16610	COG3174	membrane
PS273GM_RS16615	COG0784	Response regulator, receiver
PS273GM_RS16615	COG2205	protein histidine kinase activity
PS273GM_RS16645	COG4580	involved in the transport of maltose and maltodextrins
PS273GM_RS16665	COG0366	Alpha amylase catalytic
PS273GM_RS16670	COG2182	Extracellular solute-binding protein
PS273GM_RS16675	COG1175	transmembrane transport
PS273GM_RS16680	COG3833	ABC-type maltose transport systems, permease component
PS273GM_RS16685	COG2909	trisaccharide binding
PS273GM_RS16700	COG0366	Alpha amylase catalytic
PS273GM_RS16710	COG2076	Multidrug Resistance protein
PS273GM_RS16715	COG0385	Bile acid
PS273GM_RS16720	COG2974	May be involved in recombination
PS273GM_RS16735	COG0545	Peptidyl-prolyl cis-trans isomerase
PS273GM_RS16750	COG0556	nucleotide-excision repair
PS273GM_RS16765	COG0583	DNA-binding transcription factor activity
PS273GM_RS16770	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PS273GM_RS16805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PS273GM_RS16830	COG1450	Type ii and iii secretion system protein
PS273GM_RS16835	COG3409	Peptidoglycan-binding domain 1 protein
PS273GM_RS16835	COG3267	Type II secretory pathway component ExeA
PS273GM_RS16845	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PS273GM_RS16850	COG1459	type II secretion system
PS273GM_RS16855	COG2165	general secretion pathway protein
PS273GM_RS16860	COG2165	general secretion pathway protein
PS273GM_RS16865	COG2165	general secretion pathway protein
PS273GM_RS16905	COG3005	denitrification pathway
PS273GM_RS16910	COG3043	anaerobic respiration
PS273GM_RS16915	COG0243	molybdopterin cofactor binding
PS273GM_RS16925	COG2814	Major facilitator Superfamily
PS273GM_RS16930	COG3091	SprT-like family
PS273GM_RS16950	COG0037	tRNA processing
PS273GM_RS16955	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PS273GM_RS16970	COG0776	regulation of translation
PS273GM_RS16975	COG0489	protein tyrosine kinase activity
PS273GM_RS16975	COG3206	protein involved in exopolysaccharide biosynthesis
PS273GM_RS16975	COG3206	protein involved in exopolysaccharide biosynthesis
PS273GM_RS16975	COG0489	protein tyrosine kinase activity
PS273GM_RS16985	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PS273GM_RS17000	COG2755	lipolytic protein G-D-S-L family
PS273GM_RS17000	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PS273GM_RS17030	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PS273GM_RS17040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PS273GM_RS17060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PS273GM_RS17070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PS273GM_RS17075	COG0668	transmembrane transport
PS273GM_RS17080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PS273GM_RS17105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PS273GM_RS17115	COG2988	succinylglutamate desuccinylase activity
PS273GM_RS17125	COG1770	oligopeptidase
PS273GM_RS17130	COG1024	Enoyl-CoA hydratase
PS273GM_RS17130	COG1250	3-hydroxyacyl-CoA dehydrogenase
PS273GM_RS17135	COG0183	Belongs to the thiolase family
PS273GM_RS17170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PS273GM_RS17220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PS273GM_RS17225	COG1012	belongs to the aldehyde dehydrogenase family
PS273GM_RS17255	COG1079	Belongs to the binding-protein-dependent transport system permease family
PS273GM_RS17260	COG4603	Belongs to the binding-protein-dependent transport system permease family
PS273GM_RS17265	COG3845	ABC transporter
PS273GM_RS17275	COG4221	oxidoreductase activity
PS273GM_RS17285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PS273GM_RS17315	COG1309	transcriptional regulator
PS273GM_RS17325	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PS273GM_RS17340	COG2204	response regulator
PS273GM_RS17365	COG0297	glycogen (starch) synthase activity
PS273GM_RS17385	COG0438	transferase activity, transferring glycosyl groups
PS273GM_RS17440	COG2200	EAL domain
PS273GM_RS17445	COG0793	Belongs to the peptidase S41A family
PS273GM_RS17455	COG1362	aminopeptidase activity
PS273GM_RS17460	COG0564	pseudouridine synthase activity
PS273GM_RS17465	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PS273GM_RS17470	COG2894	cell division
PS273GM_RS17475	COG0850	regulation of cytokinetic process
PS273GM_RS17480	COG1560	Kdo2-lipid A biosynthetic process
PS273GM_RS17490	COG2853	Lipoprotein
PS273GM_RS17505	COG3162	membrane
PS273GM_RS17530	COG3089	Belongs to the UPF0270 family
PS273GM_RS17535	COG2205	protein histidine kinase activity
PS273GM_RS17535	COG0784	Response regulator, receiver
PS273GM_RS17535	COG5002	protein histidine kinase activity
PS273GM_RS17540	COG1363	Peptidase, m42
PS273GM_RS17545	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PS273GM_RS17545	COG0189	ligase activity
PS273GM_RS17550	COG0367	asparagine synthase
PS273GM_RS17560	COG0583	DNA-binding transcription factor activity
PS273GM_RS17570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PS273GM_RS17570	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PS273GM_RS17580	COG0183	Belongs to the thiolase family
PS273GM_RS17585	COG0114	fumarate hydratase activity
PS273GM_RS17595	COG0271	Belongs to the BolA IbaG family
PS273GM_RS17600	COG1054	Belongs to the UPF0176 family
PS273GM_RS17610	COG1132	(ABC) transporter
PS273GM_RS17615	COG0840	transmembrane signaling receptor activity
PS273GM_RS17645	COG1960	acyl-CoA dehydrogenase activity
PS273GM_RS17650	COG1131	(ABC) transporter
PS273GM_RS17655	COG0842	Transport permease protein
PS273GM_RS17670	COG2853	Lipoprotein
PS273GM_RS17680	COG0745	RESPONSE REGULATOR receiver
PS273GM_RS17690	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PS273GM_RS17695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PS273GM_RS17715	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
PS273GM_RS17740	COG0489	protein tyrosine kinase activity
PS273GM_RS17740	COG3206	protein involved in exopolysaccharide biosynthesis
PS273GM_RS17745	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PS273GM_RS17750	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PS273GM_RS17760	COG0835	chemotaxis
PS273GM_RS17760	COG0784	Response regulator, receiver
PS273GM_RS17765	COG0633	Ferredoxin
PS273GM_RS17765	COG3217	Mosc domain protein beta barrel domain protein
PS273GM_RS17770	COG0741	lytic transglycosylase activity
PS273GM_RS17775	COG0488	(ABC) transporter
PS273GM_RS17785	COG0589	response to stress
PS273GM_RS17795	COG0121	glutamine amidotransferase
PS273GM_RS17820	COG0542	response to heat
PS273GM_RS17830	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PS273GM_RS17840	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
PS273GM_RS17855	COG2832	Protein of unknown function (DUF454)
PS273GM_RS17865	COG0514	ATP-dependent DNA helicase (RecQ)
PS273GM_RS17880	COG1752	Esterase of the alpha-beta hydrolase superfamily
PS273GM_RS17900	COG1012	belongs to the aldehyde dehydrogenase family
PS273GM_RS17910	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PS273GM_RS17955	COG2354	Protein conserved in bacteria
PS273GM_RS17960	COG0590	tRNA wobble adenosine to inosine editing
PS273GM_RS17965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PS273GM_RS17970	COG0727	PFAM Uncharacterised protein family (UPF0153)
PS273GM_RS17975	COG0778	Nitroreductase
PS273GM_RS17990	COG0745	RESPONSE REGULATOR receiver
PS273GM_RS18000	COG2350	Protein conserved in bacteria
PS273GM_RS18005	COG2917	probably involved in intracellular septation
PS273GM_RS18010	COG0613	PHP domain protein
PS273GM_RS18015	COG0009	L-threonylcarbamoyladenylate synthase
PS273GM_RS18020	COG0180	Tryptophanyl-tRNA synthetase
PS273GM_RS18025	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PS273GM_RS18030	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PS273GM_RS18065	COG1653	transport
PS273GM_RS18070	COG1175	transmembrane transport
PS273GM_RS18075	COG0395	ABC-type sugar transport system, permease component
PS273GM_RS18080	COG3842	ATPase activity
PS273GM_RS18095	COG1737	Transcriptional regulator
PS273GM_RS18110	COG0800	Aldolase
PS273GM_RS18125	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS18130	COG0546	phosphoglycolate phosphatase activity
PS273GM_RS18135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PS273GM_RS18140	COG0402	S-adenosylhomocysteine deaminase activity
PS273GM_RS18215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PS273GM_RS18230	COG0723	plastoquinol--plastocyanin reductase activity
PS273GM_RS18245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PS273GM_RS18265	COG0546	phosphoglycolate phosphatase activity
PS273GM_RS18275	COG3383	formate dehydrogenase (NAD+) activity
PS273GM_RS18285	COG0437	4 iron, 4 sulfur cluster binding
PS273GM_RS18320	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PS273GM_RS18330	COG1845	cytochrome c oxidase, subunit III
PS273GM_RS18340	COG0587	DNA-directed DNA polymerase activity
PS273GM_RS18370	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PS273GM_RS18380	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PS273GM_RS18385	COG0077	Prephenate dehydratase
PS273GM_RS18385	COG1605	Chorismate mutase
PS273GM_RS18390	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PS273GM_RS18395	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PS273GM_RS18400	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PS273GM_RS18415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PS273GM_RS18420	COG0625	glutathione transferase activity
PS273GM_RS18425	COG0302	gtp cyclohydrolase
PS273GM_RS18430	COG2840	Smr protein MutS2
PS273GM_RS18460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PS273GM_RS18470	COG0235	Class ii aldolase
PS273GM_RS18475	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PS273GM_RS18480	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
PS273GM_RS18505	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PS273GM_RS18530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PS273GM_RS18545	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PS273GM_RS18575	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PS273GM_RS18580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PS273GM_RS18590	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PS273GM_RS18615	COG0348	domain, Protein
PS273GM_RS18620	COG2010	Cytochrome c
PS273GM_RS18635	COG3278	Belongs to the heme-copper respiratory oxidase family
PS273GM_RS18650	COG3278	Belongs to the heme-copper respiratory oxidase family
PS273GM_RS18660	COG0840	transmembrane signaling receptor activity
PS273GM_RS18670	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
PS273GM_RS18685	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PS273GM_RS18690	COG2010	Cytochrome c
PS273GM_RS18690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PS273GM_RS18700	COG1981	membrane
PS273GM_RS18705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PS273GM_RS18710	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PS273GM_RS18720	COG3115	cell septum assembly
PS273GM_RS18725	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PS273GM_RS18730	COG0720	synthase
PS273GM_RS18735	COG2056	Na+-H+ antiporter family
PS273GM_RS18740	COG0628	permease
PS273GM_RS18750	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PS273GM_RS18755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PS273GM_RS18760	COG3265	gluconokinase activity
PS273GM_RS18765	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PS273GM_RS18770	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PS273GM_RS18775	COG1609	Transcriptional regulator
PS273GM_RS18790	COG1070	Carbohydrate kinase
PS273GM_RS18810	COG1175	transmembrane transport
PS273GM_RS18845	COG0729	surface antigen
PS273GM_RS18850	COG2911	Protein conserved in bacteria
PS273GM_RS18855	COG1115	amino acid carrier protein
PS273GM_RS18870	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PS273GM_RS18880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PS273GM_RS18895	COG0544	peptidyl-prolyl cis-trans isomerase activity
PS273GM_RS18900	COG0740	serine-type endopeptidase activity
PS273GM_RS18905	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PS273GM_RS18910	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PS273GM_RS18920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PS273GM_RS18930	COG4172	Belongs to the ABC transporter superfamily
PS273GM_RS18935	COG4239	(ABC) transporter, permease
PS273GM_RS18940	COG4174	ABC transporter (Permease)
PS273GM_RS18950	COG4166	transmembrane transport
PS273GM_RS18960	COG1388	LysM domain
PS273GM_RS18960	COG0741	lytic transglycosylase activity
PS273GM_RS18975	COG0328	RNA-DNA hybrid ribonuclease activity
PS273GM_RS18980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PS273GM_RS18990	COG1024	Enoyl-CoA hydratase
PS273GM_RS19000	COG2816	NAD+ diphosphatase activity
PS273GM_RS19015	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS19035	COG0616	signal peptide processing
PS273GM_RS19040	COG0604	alcohol dehydrogenase
PS273GM_RS19085	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PS273GM_RS19090	COG2223	nitrite transmembrane transporter activity
PS273GM_RS19100	COG1846	Transcriptional regulator
PS273GM_RS19120	COG0316	Belongs to the HesB IscA family
PS273GM_RS19120	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PS273GM_RS19125	COG2197	response regulator
PS273GM_RS19130	COG3706	GGDEF domain
PS273GM_RS19150	COG0840	transmembrane signaling receptor activity
PS273GM_RS19155	COG1968	undecaprenyl-diphosphatase activity
PS273GM_RS19160	COG2267	carboxylic ester hydrolase activity
PS273GM_RS19165	COG1278	Cold shock
PS273GM_RS19170	COG0488	(ABC) transporter
PS273GM_RS19185	COG0589	response to stress
PS273GM_RS19195	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PS273GM_RS19200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PS273GM_RS19205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PS273GM_RS19210	COG0215	cysteine-tRNA ligase activity
PS273GM_RS19215	COG3284	Transcriptional regulator
PS273GM_RS19225	COG3842	ATPase activity
PS273GM_RS19235	COG0395	ABC-type sugar transport system, permease component
PS273GM_RS19250	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PS273GM_RS19310	COG5654	RES domain protein
PS273GM_RS19315	COG5642	Protein of unknown function (DUF2384)
PS273GM_RS19320	COG0728	peptidoglycan biosynthetic process
PS273GM_RS19385	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS19390	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PS273GM_RS19400	COG3383	formate dehydrogenase (NAD+) activity
PS273GM_RS19400	COG0243	molybdopterin cofactor binding
PS273GM_RS19405	COG3383	formate dehydrogenase (NAD+) activity
PS273GM_RS19405	COG0243	molybdopterin cofactor binding
PS273GM_RS19410	COG0437	4 iron, 4 sulfur cluster binding
PS273GM_RS19415	COG2864	formate dehydrogenase
PS273GM_RS19430	COG0366	Alpha amylase catalytic
PS273GM_RS19435	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PS273GM_RS19440	COG0392	lysyltransferase activity
PS273GM_RS19445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PS273GM_RS19450	COG3568	Endonuclease Exonuclease Phosphatase
PS273GM_RS19465	COG0583	DNA-binding transcription factor activity
PS273GM_RS19470	COG3384	dioxygenase
PS273GM_RS19480	COG0739	heme binding
PS273GM_RS19505	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PS273GM_RS19510	COG0297	glycogen (starch) synthase activity
PS273GM_RS19515	COG1058	Belongs to the CinA family
PS273GM_RS19515	COG1546	Belongs to the CinA family
PS273GM_RS19520	COG3264	Mechanosensitive ion channel
PS273GM_RS19520	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PS273GM_RS19525	COG3685	Protein conserved in bacteria
PS273GM_RS19560	COG2847	Copper chaperone PCu(A)C
PS273GM_RS19610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PS273GM_RS19615	COG0277	FAD linked oxidase domain protein
PS273GM_RS19620	COG2721	sulfolactate sulfo-lyase activity
PS273GM_RS19630	COG1012	belongs to the aldehyde dehydrogenase family
PS273GM_RS19635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PS273GM_RS19650	COG3181	Tripartite tricarboxylate transporter family receptor
PS273GM_RS19670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PS273GM_RS19680	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PS273GM_RS19765	COG0701	Predicted permease
PS273GM_RS19785	COG0431	NADPH-dependent FMN reductase
PS273GM_RS19790	COG1742	UPF0060 membrane protein
PS273GM_RS19795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PS273GM_RS19805	COG0784	Response regulator, receiver
PS273GM_RS19805	COG2205	protein histidine kinase activity
PS273GM_RS19820	COG0535	radical SAM domain protein
PS273GM_RS19830	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
PS273GM_RS19835	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PS273GM_RS19865	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PS273GM_RS19870	COG0167	dihydroorotate dehydrogenase activity
PS273GM_RS19885	COG0477	Major facilitator Superfamily
PS273GM_RS19895	COG2205	protein histidine kinase activity
PS273GM_RS19920	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PS273GM_RS19945	COG2323	membrane
PS273GM_RS19970	COG3851	Histidine kinase
PS273GM_RS19995	COG1131	(ABC) transporter
PS273GM_RS20010	COG2205	protein histidine kinase activity
PS273GM_RS20010	COG0784	Response regulator, receiver
PS273GM_RS20025	COG1025	Belongs to the peptidase M16 family
PS273GM_RS20045	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PS273GM_RS20050	COG1366	Belongs to the anti-sigma-factor antagonist family
PS273GM_RS20060	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PS273GM_RS20065	COG1090	epimerase
PS273GM_RS20075	COG3272	Protein of unknown function (DUF1722)
PS273GM_RS20080	COG0789	Transcriptional regulator
PS273GM_RS20115	COG0625	glutathione transferase activity
PS273GM_RS20120	COG0210	DNA helicase
PS273GM_RS20125	COG3284	Transcriptional regulator
PS273GM_RS20140	COG4294	response to UV
PS273GM_RS20165	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PS273GM_RS20175	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PS273GM_RS20175	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PS273GM_RS20175	COG0506	proline dehydrogenase activity
PS273GM_RS20185	COG4771	TonB-dependent receptor
PS273GM_RS20190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PS273GM_RS20195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PS273GM_RS20200	COG1120	ATPase activity
PS273GM_RS20210	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PS273GM_RS20220	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS20225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PS273GM_RS20230	COG3433	isochorismatase activity
PS273GM_RS20230	COG1535	isochorismatase
PS273GM_RS20235	COG1021	2,3-dihydroxybenzoate-AMP ligase
PS273GM_RS20240	COG1169	isochorismate synthase
PS273GM_RS20245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PS273GM_RS20270	COG3665	Urea carboxylase-associated protein
PS273GM_RS20280	COG0439	Biotin carboxylase
PS273GM_RS20295	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PS273GM_RS20305	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS20325	COG1335	isochorismatase
PS273GM_RS20340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PS273GM_RS20385	COG0004	ammonium transporteR
PS273GM_RS20390	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PS273GM_RS20395	COG0174	glutamine synthetase
PS273GM_RS20415	COG0745	RESPONSE REGULATOR receiver
PS273GM_RS20420	COG3920	Histidine kinase
PS273GM_RS20435	COG1024	Enoyl-CoA hydratase
PS273GM_RS20440	COG1960	acyl-CoA dehydrogenase activity
PS273GM_RS20445	COG0318	PFAM AMP-dependent synthetase and ligase
PS273GM_RS20450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PS273GM_RS20455	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PS273GM_RS20465	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
PS273GM_RS20485	COG2258	MOSC domain
PS273GM_RS20495	COG1960	acyl-CoA dehydrogenase activity
PS273GM_RS20520	COG1024	Enoyl-CoA hydratase
PS273GM_RS20530	COG0559	Belongs to the binding-protein-dependent transport system permease family
PS273GM_RS20560	COG0318	PFAM AMP-dependent synthetase and ligase
PS273GM_RS20565	COG1960	acyl-CoA dehydrogenase activity
PS273GM_RS20570	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PS273GM_RS20605	COG0789	Transcriptional regulator
PS273GM_RS20610	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
PS273GM_RS20620	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
PS273GM_RS20635	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS20650	COG3300	MHYT domain
PS273GM_RS20650	COG5001	Diguanylate cyclase
PS273GM_RS20660	COG5001	Diguanylate cyclase
PS273GM_RS20690	COG0025	NhaP-type Na H and K H
PS273GM_RS20700	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PS273GM_RS20710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PS273GM_RS20720	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PS273GM_RS20725	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PS273GM_RS20730	COG1414	Transcriptional regulator
PS273GM_RS20740	COG0583	DNA-binding transcription factor activity
PS273GM_RS20745	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PS273GM_RS20760	COG2031	fatty acid transporter
PS273GM_RS20765	COG0840	transmembrane signaling receptor activity
PS273GM_RS20775	COG1696	Membrane protein involved in D-alanine export
PS273GM_RS20800	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
PS273GM_RS20830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PS273GM_RS20855	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PS273GM_RS20860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PS273GM_RS20925	COG2130	NADP-dependent
PS273GM_RS20940	COG2146	nitrite reductase [NAD(P)H] activity
PS273GM_RS20940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PS273GM_RS20950	COG2116	formate transmembrane transporter activity
PS273GM_RS20955	COG0515	serine threonine protein kinase
PS273GM_RS20955	COG2815	serine threonine protein kinase
PS273GM_RS20965	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
PS273GM_RS20965	COG0493	'glutamate synthase
PS273GM_RS20980	COG4991	sh3 domain protein
PS273GM_RS20990	COG1366	Belongs to the anti-sigma-factor antagonist family
PS273GM_RS20995	COG1366	Belongs to the anti-sigma-factor antagonist family
PS273GM_RS21000	COG2172	sigma factor antagonist activity
PS273GM_RS21010	COG2205	protein histidine kinase activity
PS273GM_RS21025	COG0530	calcium, potassium:sodium antiporter activity
PS273GM_RS21030	COG0417	DNA replication proofreading
PS273GM_RS21040	COG0835	chemotaxis
PS273GM_RS21040	COG0784	Response regulator, receiver
PS273GM_RS21045	COG0183	Belongs to the thiolase family
PS273GM_RS21050	COG3901	Regulator of nitric oxide reductase transcription
PS273GM_RS21050	COG0348	domain, Protein
PS273GM_RS21080	COG5002	protein histidine kinase activity
PS273GM_RS21095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PS273GM_RS21105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PS273GM_RS21120	COG3220	belongs to the UPF0276 family
PS273GM_RS21130	COG1595	DNA-templated transcription, initiation
PS273GM_RS21135	COG4944	Protein of unknown function (DUF1109)
PS273GM_RS21180	COG0697	spore germination
PS273GM_RS21195	COG0747	negative chemotaxis
PS273GM_RS21200	COG0601	transmembrane transport
PS273GM_RS21205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PS273GM_RS21210	COG0444	Belongs to the ABC transporter superfamily
PS273GM_RS21215	COG4608	Belongs to the ABC transporter superfamily
PS273GM_RS21245	COG2168	tRNA wobble position uridine thiolation
PS273GM_RS21255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PS273GM_RS21260	COG0435	Glutathione S-transferase
PS273GM_RS21265	COG1648	precorrin-2 dehydrogenase activity
PS273GM_RS21265	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PS273GM_RS21275	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PS273GM_RS21280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PS273GM_RS21285	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PS273GM_RS21290	COG1674	ftsk spoiiie
PS273GM_RS21295	COG0492	ferredoxin-NADP+ reductase activity
PS273GM_RS21300	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PS273GM_RS21305	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PS273GM_RS21310	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PS273GM_RS21315	COG0542	response to heat
PS273GM_RS21320	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PS273GM_RS21325	COG1278	Cold shock
PS273GM_RS21345	COG0482	sulfurtransferase activity
PS273GM_RS21350	COG2915	High frequency lysogenization protein hflD homolog
PS273GM_RS21360	COG2850	peptidyl-arginine hydroxylation
PS273GM_RS21365	COG2153	protein acetylation
PS273GM_RS21395	COG0668	transmembrane transport
PS273GM_RS21410	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PS273GM_RS21420	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PS273GM_RS21435	COG0372	Belongs to the citrate synthase family
PS273GM_RS21445	COG1802	Transcriptional regulator
PS273GM_RS21470	COG0560	Phosphoserine phosphatase
PS273GM_RS21485	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PS273GM_RS21520	COG4181	ATPase activity
PS273GM_RS21525	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PS273GM_RS21545	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PS273GM_RS21550	COG0084	hydrolase, TatD family'
PS273GM_RS21575	COG0714	Associated with various cellular activities
PS273GM_RS21580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PS273GM_RS21590	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PS273GM_RS21595	COG0709	Synthesizes selenophosphate from selenide and ATP
PS273GM_RS21605	COG0628	permease
PS273GM_RS21645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PS273GM_RS21655	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PS273GM_RS21700	COG0045	succinate-CoA ligase (ADP-forming) activity
PS273GM_RS21720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PS273GM_RS21725	COG1053	succinate dehydrogenase
PS273GM_RS21730	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PS273GM_RS21735	COG2009	succinate dehydrogenase
PS273GM_RS21755	COG0776	regulation of translation
PS273GM_RS21760	COG0072	phenylalanine-tRNA ligase activity
PS273GM_RS21765	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PS273GM_RS21770	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PS273GM_RS21775	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PS273GM_RS21780	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PS273GM_RS21785	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PS273GM_RS21795	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PS273GM_RS21870	COG3171	Protein conserved in bacteria
PS273GM_RS21875	COG2027	D-alanyl-D-alanine carboxypeptidase
PS273GM_RS21880	COG0116	Belongs to the methyltransferase superfamily
PS273GM_RS21880	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PS273GM_RS21890	COG0167	dihydroorotate dehydrogenase activity
PS273GM_RS21910	COG0714	Associated with various cellular activities
PS273GM_RS21930	COG2304	oxidoreductase activity
PS273GM_RS21940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PS273GM_RS21945	COG2197	response regulator
PS273GM_RS21950	COG1116	anion transmembrane transporter activity
PS273GM_RS21950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PS273GM_RS21955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PS273GM_RS21960	COG1116	anion transmembrane transporter activity
PS273GM_RS21985	COG2223	nitrite transmembrane transporter activity
PS273GM_RS22000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PS273GM_RS22005	COG2146	nitrite reductase [NAD(P)H] activity
PS273GM_RS22010	COG0243	molybdopterin cofactor binding
PS273GM_RS22030	COG0308	aminopeptidase N
PS273GM_RS22050	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PS273GM_RS22055	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PS273GM_RS22070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PS273GM_RS22090	COG0446	pyridine nucleotide-disulphide oxidoreductase
PS273GM_RS22090	COG1902	pentaerythritol trinitrate reductase activity
PS273GM_RS22110	COG1294	oxidase, subunit
PS273GM_RS22115	COG1271	oxidase subunit
PS273GM_RS22150	COG1286	toxin biosynthetic process
PS273GM_RS22155	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PS273GM_RS22160	COG0285	dihydrofolate synthase activity
PS273GM_RS22165	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PS273GM_RS22170	COG0135	phosphoribosylanthranilate isomerase activity
PS273GM_RS22190	COG0473	3-isopropylmalate dehydrogenase activity
PS273GM_RS22195	COG0066	3-isopropylmalate dehydratase activity
PS273GM_RS22200	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PS273GM_RS22220	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS22250	COG1555	photosystem II stabilization
PS273GM_RS22260	COG1256	bacterial-type flagellum assembly
PS273GM_RS22270	COG1706	bacterial-type flagellum-dependent cell motility
PS273GM_RS22275	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PS273GM_RS22285	COG4787	bacterial-type flagellum-dependent cell motility
PS273GM_RS22305	COG1815	bacterial-type flagellum-dependent cell motility
PS273GM_RS22310	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PS273GM_RS22315	COG0784	Response regulator, receiver
PS273GM_RS22315	COG0835	chemotaxis
PS273GM_RS22335	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
PS273GM_RS22360	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
PS273GM_RS22365	COG5016	pyruvate
PS273GM_RS22365	COG0511	ligase activity, forming carbon-carbon bonds
PS273GM_RS22375	COG2239	Acts as a magnesium transporter
PS273GM_RS22400	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PS273GM_RS22405	COG0527	aspartate kinase activity
PS273GM_RS22410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PS273GM_RS22425	COG2983	Belongs to the UPF0260 family
PS273GM_RS22435	COG3100	YcgL domain-containing protein
PS273GM_RS22450	COG2067	long-chain fatty acid transport protein
PS273GM_RS22480	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PS273GM_RS22485	COG0406	alpha-ribazole phosphatase activity
PS273GM_RS22500	COG1492	cobalamin metabolic process
PS273GM_RS22510	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PS273GM_RS22515	COG0778	Nitroreductase
PS273GM_RS22520	COG1797	cobyrinic acid a,c-diamide synthase activity
PS273GM_RS22535	COG4206	TonB-dependent receptor
PS273GM_RS22545	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PS273GM_RS22555	COG0791	NLP P60 protein
PS273GM_RS22560	COG0791	NLP P60 protein
PS273GM_RS22580	COG4890	Cyd operon protein YbgT
PS273GM_RS22585	COG1294	oxidase, subunit
PS273GM_RS22610	COG2818	Glycosylase
PS273GM_RS22615	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PS273GM_RS22620	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PS273GM_RS22635	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
PS273GM_RS22650	COG4591	ABC-type transport system involved in lipoprotein release permease component
PS273GM_RS22655	COG1136	(ABC) transporter
PS273GM_RS22675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PS273GM_RS22715	COG0625	glutathione transferase activity
PS273GM_RS22725	COG0386	Belongs to the glutathione peroxidase family
PS273GM_RS22730	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PS273GM_RS22735	COG0436	Aminotransferase
PS273GM_RS22745	COG0501	Belongs to the peptidase M48B family
PS273GM_RS22755	COG0500	methyltransferase
PS273GM_RS22800	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PS273GM_RS22830	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PS273GM_RS22845	COG0835	chemotaxis
PS273GM_RS22855	COG1192	Involved in chromosome partitioning
PS273GM_RS22860	COG1360	Flagellar Motor Protein
PS273GM_RS22865	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PS273GM_RS22870	COG2201	protein-glutamate methylesterase activity
PS273GM_RS22875	COG0643	Histidine kinase
PS273GM_RS22875	COG0784	Response regulator, receiver
PS273GM_RS22875	COG2198	Histidine kinase
PS273GM_RS22880	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
PS273GM_RS22925	COG1987	bacterial-type flagellum assembly
PS273GM_RS22950	COG1580	Controls the rotational direction of flagella during chemotaxis
PS273GM_RS22965	COG0745	RESPONSE REGULATOR receiver
PS273GM_RS23000	COG1677	Flagellar hook-basal body complex protein FliE
PS273GM_RS23005	COG3135	benzoate transporter
PS273GM_RS23010	COG1028	Short-chain dehydrogenase reductase Sdr
PS273GM_RS23020	COG2130	NADP-dependent
PS273GM_RS23030	COG5001	Diguanylate cyclase
PS273GM_RS23040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PS273GM_RS23075	COG1278	Cold shock
PS273GM_RS23095	COG2937	Belongs to the GPAT DAPAT family
PS273GM_RS23115	COG1272	protein, Hemolysin III
PS273GM_RS23135	COG2217	Heavy metal translocating P-type atpase
PS273GM_RS23145	COG2132	Multicopper oxidase
PS273GM_RS23165	COG2943	transferase activity, transferring hexosyl groups
PS273GM_RS23170	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
PS273GM_RS23195	COG1793	dna ligase
PS273GM_RS23205	COG1201	RNA secondary structure unwinding
PS273GM_RS23235	COG3956	TIGRFAM MazG family protein