locus-tag	class	description
PverR02_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PverR02_RS00010	COG0592	DNA-directed DNA polymerase activity
PverR02_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PverR02_RS00020	COG0187	DNA topoisomerase II activity
PverR02_RS00030	COG1773	rubredoxin
PverR02_RS00030	COG0426	domain, Protein
PverR02_RS00035	COG3604	Transcriptional regulator
PverR02_RS00040	COG2124	cytochrome p450
PverR02_RS00060	COG0583	DNA-binding transcription factor activity
PverR02_RS00065	COG0745	RESPONSE REGULATOR receiver
PverR02_RS00070	COG5002	protein histidine kinase activity
PverR02_RS00080	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PverR02_RS00085	COG0751	glycine-tRNA ligase activity
PverR02_RS00090	COG0752	glycyl-tRNA synthetase alpha subunit
PverR02_RS00095	COG2818	Glycosylase
PverR02_RS00110	COG0569	domain protein
PverR02_RS00115	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PverR02_RS00120	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PverR02_RS00125	COG0242	peptide deformylase activity
PverR02_RS00135	COG0758	DNA mediated transformation
PverR02_RS00140	COG0009	L-threonylcarbamoyladenylate synthase
PverR02_RS00150	COG0408	coproporphyrinogen oxidase activity
PverR02_RS00155	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PverR02_RS00170	COG3119	arylsulfatase activity
PverR02_RS00175	COG0583	DNA-binding transcription factor activity
PverR02_RS00185	COG3734	2-keto-3-deoxy-galactonokinase
PverR02_RS00190	COG0800	Aldolase
PverR02_RS00195	COG4948	Mandelate Racemase Muconate Lactonizing
PverR02_RS00200	COG2271	Major facilitator Superfamily
PverR02_RS00215	COG0159	tryptophan synthase activity
PverR02_RS00235	COG3360	Dodecin
PverR02_RS00245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PverR02_RS00250	COG1764	response to oxidative stress
PverR02_RS00275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PverR02_RS00280	COG0339	signal peptide processing
PverR02_RS00320	COG0659	secondary active sulfate transmembrane transporter activity
PverR02_RS00330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PverR02_RS00335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PverR02_RS00340	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
PverR02_RS00370	COG0109	protoheme IX farnesyltransferase activity
PverR02_RS00385	COG2011	ABC-type metal ion transport system permease component
PverR02_RS00390	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PverR02_RS00405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PverR02_RS00410	COG1121	(ABC) transporter
PverR02_RS00415	COG0735	belongs to the Fur family
PverR02_RS00420	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
PverR02_RS00440	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PverR02_RS00445	COG3245	cytochrome
PverR02_RS00455	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PverR02_RS00470	COG3023	N-Acetylmuramoyl-L-alanine amidase
PverR02_RS00475	COG5002	protein histidine kinase activity
PverR02_RS00480	COG2204	response regulator
PverR02_RS00490	COG5487	UPF0391 membrane protein
PverR02_RS00500	COG1301	dicarboxylic acid transport
PverR02_RS00505	COG0700	Nucleoside recognition
PverR02_RS00520	COG1127	ABC transporter
PverR02_RS00525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PverR02_RS00535	COG0612	Peptidase, M16
PverR02_RS00540	COG1283	sodium-dependent phosphate transmembrane transporter activity
PverR02_RS00545	COG0861	Integral membrane protein TerC family
PverR02_RS00550	COG2851	Citrate transporter
PverR02_RS00585	COG0427	acetyl-CoA hydrolase
PverR02_RS00605	COG0583	DNA-binding transcription factor activity
PverR02_RS00610	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS00615	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PverR02_RS00655	COG0840	transmembrane signaling receptor activity
PverR02_RS00665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PverR02_RS00680	COG1802	Transcriptional regulator
PverR02_RS00685	COG2175	clavaminate synthase activity
PverR02_RS00700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PverR02_RS00805	COG1289	transmembrane transporter activity
PverR02_RS00830	COG5339	Protein conserved in bacteria
PverR02_RS00840	COG0457	Tetratricopeptide repeat
PverR02_RS00845	COG1649	PFAM Uncharacterised BCR, COG1649
PverR02_RS00845	COG0726	polysaccharide deacetylase
PverR02_RS00850	COG1215	transferase activity, transferring glycosyl groups
PverR02_RS00860	COG2831	hemolysin activation secretion protein
PverR02_RS00900	COG3209	COG3209 Rhs family protein
PverR02_RS00950	COG2304	oxidoreductase activity
PverR02_RS00955	COG1595	DNA-templated transcription, initiation
PverR02_RS00965	COG1063	alcohol dehydrogenase
PverR02_RS00985	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PverR02_RS00990	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PverR02_RS01035	COG0582	viral genome integration into host DNA
PverR02_RS01045	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS01050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PverR02_RS01060	COG2199	diguanylate cyclase activity
PverR02_RS01080	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PverR02_RS01090	COG4208	sulfate ABC transporter
PverR02_RS01095	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PverR02_RS01105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PverR02_RS01120	COG3829	transcription factor binding
PverR02_RS01165	COG2011	ABC-type metal ion transport system permease component
PverR02_RS01170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PverR02_RS01200	COG1126	abc transporter atp-binding protein
PverR02_RS01205	COG0765	amino acid transport
PverR02_RS01210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PverR02_RS01220	COG1045	serine acetyltransferase
PverR02_RS01225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PverR02_RS01235	COG0667	Aldo Keto reductase
PverR02_RS01240	COG2175	clavaminate synthase activity
PverR02_RS01245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PverR02_RS01250	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PverR02_RS01255	COG4521	taurine ABC transporter
PverR02_RS01260	COG2918	glutathione biosynthetic process
PverR02_RS01270	COG2183	response to ionizing radiation
PverR02_RS01285	COG0189	ligase activity
PverR02_RS01290	COG4067	protein conserved in archaea
PverR02_RS01290	COG0189	ligase activity
PverR02_RS01295	COG2200	EAL domain
PverR02_RS01300	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PverR02_RS01310	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PverR02_RS01315	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PverR02_RS01335	COG2184	nucleotidyltransferase activity
PverR02_RS01350	COG0824	Thioesterase
PverR02_RS01360	COG0243	molybdopterin cofactor binding
PverR02_RS01365	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PverR02_RS01375	COG1652	LysM domain
PverR02_RS01380	COG1011	Hydrolase
PverR02_RS01385	COG0494	nUDIX hydrolase
PverR02_RS01390	COG1218	3'(2'),5'-bisphosphate nucleotidase
PverR02_RS01430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PverR02_RS01435	COG2957	Belongs to the agmatine deiminase family
PverR02_RS01450	COG0501	Belongs to the peptidase M48B family
PverR02_RS01475	COG2267	carboxylic ester hydrolase activity
PverR02_RS01485	COG1902	pentaerythritol trinitrate reductase activity
PverR02_RS01525	COG0582	viral genome integration into host DNA
PverR02_RS01535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PverR02_RS01655	COG3300	MHYT domain
PverR02_RS01655	COG5001	Diguanylate cyclase
PverR02_RS01735	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
PverR02_RS01740	COG1194	a g-specific adenine glycosylase
PverR02_RS01750	COG2223	nitrite transmembrane transporter activity
PverR02_RS01755	COG0131	Imidazoleglycerol-phosphate dehydratase
PverR02_RS01760	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PverR02_RS01770	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PverR02_RS01775	COG0107	imidazoleglycerol-phosphate synthase activity
PverR02_RS01785	COG2861	carbohydrate metabolic process
PverR02_RS01790	COG0793	Belongs to the peptidase S41A family
PverR02_RS01795	COG4942	peptidase
PverR02_RS01800	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PverR02_RS01805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PverR02_RS01815	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
PverR02_RS01840	COG3852	Histidine kinase
PverR02_RS01860	COG0301	tRNA thio-modification
PverR02_RS01860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PverR02_RS01865	COG1217	gtp-binding protein TYPA
PverR02_RS01875	COG0058	SHG alpha-glucan phosphorylase activity
PverR02_RS01890	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PverR02_RS01905	COG0402	S-adenosylhomocysteine deaminase activity
PverR02_RS01910	COG2188	Transcriptional regulator
PverR02_RS01920	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PverR02_RS01925	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PverR02_RS01935	COG4176	ABC-type proline glycine betaine transport system permease component
PverR02_RS01940	COG4175	Glycine betaine
PverR02_RS01940	COG0517	IMP dehydrogenase activity
PverR02_RS01945	COG2986	histidine ammonia-lyase
PverR02_RS01950	COG2986	histidine ammonia-lyase
PverR02_RS01955	COG1228	amidohydrolase
PverR02_RS01990	COG3209	COG3209 Rhs family protein
PverR02_RS02010	COG1490	D-aminoacyl-tRNA deacylase activity
PverR02_RS02015	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
PverR02_RS02020	COG2943	transferase activity, transferring hexosyl groups
PverR02_RS02030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PverR02_RS02035	COG0765	amino acid transport
PverR02_RS02040	COG1126	abc transporter atp-binding protein
PverR02_RS02045	COG0840	transmembrane signaling receptor activity
PverR02_RS02050	COG0840	transmembrane signaling receptor activity
PverR02_RS02065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PverR02_RS02070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PverR02_RS02075	COG0140	phosphoribosyl-ATP diphosphatase activity
PverR02_RS02080	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PverR02_RS02085	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PverR02_RS02095	COG2226	methyltransferase
PverR02_RS02140	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PverR02_RS02145	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PverR02_RS02155	COG0018	arginyl-trna synthetase
PverR02_RS02165	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PverR02_RS02170	COG0254	rRNA binding
PverR02_RS02175	COG0281	malic enzyme
PverR02_RS02205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PverR02_RS02210	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PverR02_RS02225	COG0067	glutamate synthase
PverR02_RS02225	COG0069	glutamate synthase activity
PverR02_RS02225	COG0070	glutamate synthase
PverR02_RS02230	COG0493	'glutamate synthase
PverR02_RS02235	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PverR02_RS02245	COG2814	Major facilitator Superfamily
PverR02_RS02250	COG0583	DNA-binding transcription factor activity
PverR02_RS02260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PverR02_RS02265	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS02275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PverR02_RS02285	COG2226	methyltransferase
PverR02_RS02310	COG2986	histidine ammonia-lyase
PverR02_RS02325	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PverR02_RS02335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PverR02_RS02340	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PverR02_RS02355	COG1192	Involved in chromosome partitioning
PverR02_RS02360	COG3118	belongs to the thioredoxin family
PverR02_RS02365	COG4680	protein conserved in bacteria
PverR02_RS02370	COG5499	transcription regulator containing HTH domain
PverR02_RS02375	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
PverR02_RS02380	COG3264	Mechanosensitive ion channel
PverR02_RS02380	COG1196	nuclear chromosome segregation
PverR02_RS02385	COG3263	regulation of cellular component size
PverR02_RS02405	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS02410	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PverR02_RS02410	COG0506	proline dehydrogenase activity
PverR02_RS02410	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
PverR02_RS02415	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PverR02_RS02425	COG2873	o-acetylhomoserine
PverR02_RS02430	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
PverR02_RS02435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PverR02_RS02455	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PverR02_RS02460	COG0859	PFAM glycosyl transferase family 9
PverR02_RS02465	COG0859	PFAM glycosyl transferase family 9
PverR02_RS02470	COG0438	transferase activity, transferring glycosyl groups
PverR02_RS02505	COG2192	nodulation
PverR02_RS02520	COG0438	transferase activity, transferring glycosyl groups
PverR02_RS02525	COG1215	transferase activity, transferring glycosyl groups
PverR02_RS02535	COG1132	(ABC) transporter
PverR02_RS02540	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
PverR02_RS02540	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
PverR02_RS02550	COG0667	Aldo Keto reductase
PverR02_RS02570	COG1519	Transferase
PverR02_RS02575	COG1538	Outer membrane efflux protein
PverR02_RS02580	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PverR02_RS02595	COG0494	nUDIX hydrolase
PverR02_RS02605	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PverR02_RS02610	COG3150	esterase
PverR02_RS02640	COG0560	Phosphoserine phosphatase
PverR02_RS02640	COG3830	Belongs to the UPF0237 family
PverR02_RS02645	COG0688	phosphatidylethanolamine metabolic process
PverR02_RS02665	COG1360	Flagellar Motor Protein
PverR02_RS02670	COG1162	GTPase activity
PverR02_RS02675	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PverR02_RS02680	COG2860	membrane
PverR02_RS02690	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PverR02_RS02690	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PverR02_RS02695	COG0802	atpase or kinase
PverR02_RS02700	COG0860	N-Acetylmuramoyl-L-alanine amidase
PverR02_RS02705	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PverR02_RS02710	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PverR02_RS02715	COG1923	regulation of RNA biosynthetic process
PverR02_RS02720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PverR02_RS02725	COG0330	HflC and HflK could
PverR02_RS02730	COG0330	HflC and HflK could
PverR02_RS02735	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PverR02_RS02740	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PverR02_RS02750	COG1178	ABC-type Fe3 transport system permease component
PverR02_RS02755	COG1840	ABC-type Fe3 transport system, periplasmic component
PverR02_RS02770	COG0557	exoribonuclease II activity
PverR02_RS02775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PverR02_RS02780	COG0360	Binds together with S18 to 16S ribosomal RNA
PverR02_RS02785	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PverR02_RS02795	COG0359	binds to the 23S rRNA
PverR02_RS02800	COG0305	Participates in initiation and elongation during chromosome replication
PverR02_RS02805	COG1032	radical SAM domain protein
PverR02_RS02845	COG2307	Protein conserved in bacteria
PverR02_RS02845	COG2308	Evidence 4 Homologs of previously reported genes of
PverR02_RS02865	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PverR02_RS02870	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PverR02_RS02875	COG0583	DNA-binding transcription factor activity
PverR02_RS02880	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS02885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PverR02_RS02895	COG0559	Belongs to the binding-protein-dependent transport system permease family
PverR02_RS02920	COG4221	oxidoreductase activity
PverR02_RS02935	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PverR02_RS02940	COG0830	nickel cation binding
PverR02_RS02945	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
PverR02_RS02950	COG0791	NLP P60 protein
PverR02_RS02955	COG1309	transcriptional regulator
PverR02_RS02965	COG2982	Protein involved in outer membrane biogenesis
PverR02_RS02990	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
PverR02_RS03000	COG0697	spore germination
PverR02_RS03015	COG0443	Heat shock 70 kDa protein
PverR02_RS03020	COG0484	heat shock protein binding
PverR02_RS03025	COG0804	urea catabolic process
PverR02_RS03030	COG0832	Belongs to the urease beta subunit family
PverR02_RS03045	COG0831	urea catabolic process
PverR02_RS03050	COG0829	nickel cation binding
PverR02_RS03060	COG0411	ABC transporter
PverR02_RS03110	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PverR02_RS03115	COG3657	addiction module killer protein
PverR02_RS03130	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PverR02_RS03155	COG2095	MarC family integral membrane protein
PverR02_RS03165	COG0151	Belongs to the GarS family
PverR02_RS03170	COG0138	bifunctional purine biosynthesis protein purh
PverR02_RS03180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PverR02_RS03190	COG2264	protein methyltransferase activity
PverR02_RS03205	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PverR02_RS03235	COG0023	Translation Initiation Factor
PverR02_RS03240	COG1166	arginine decarboxylase activity
PverR02_RS03245	COG0534	Mate efflux family protein
PverR02_RS03260	COG4953	penicillin-binding protein 1C
PverR02_RS03270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PverR02_RS03290	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS03295	COG0183	Belongs to the thiolase family
PverR02_RS03310	COG2217	Heavy metal translocating P-type atpase
PverR02_RS03325	COG2814	Major facilitator Superfamily
PverR02_RS03335	COG0604	alcohol dehydrogenase
PverR02_RS03340	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
PverR02_RS03345	COG0583	DNA-binding transcription factor activity
PverR02_RS03355	COG0477	Major facilitator Superfamily
PverR02_RS03360	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PverR02_RS03365	COG0387	Pfam Sodium calcium exchanger
PverR02_RS03385	COG1309	transcriptional regulator
PverR02_RS03390	COG2233	PERMEase
PverR02_RS03440	COG2995	paraquat-inducible protein a
PverR02_RS03445	COG2995	paraquat-inducible protein a
PverR02_RS03450	COG3008	intermembrane lipid transfer
PverR02_RS03475	COG0456	acetyltransferase
PverR02_RS03485	COG0288	reversible hydration of carbon dioxide
PverR02_RS03505	COG2031	fatty acid transporter
PverR02_RS03510	COG0477	Major facilitator Superfamily
PverR02_RS03560	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PverR02_RS03565	COG2207	Transcriptional regulator
PverR02_RS03595	COG1496	oxidoreductase activity
PverR02_RS03600	COG0405	Gamma-glutamyltransferase
PverR02_RS03610	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS03630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PverR02_RS03665	COG0840	transmembrane signaling receptor activity
PverR02_RS03685	COG0583	DNA-binding transcription factor activity
PverR02_RS03690	COG0604	alcohol dehydrogenase
PverR02_RS03690	COG4221	oxidoreductase activity
PverR02_RS03690	COG3321	synthase
PverR02_RS03690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PverR02_RS03720	COG4774	siderophore transport
PverR02_RS03725	COG3712	iron ion homeostasis
PverR02_RS03730	COG1595	DNA-templated transcription, initiation
PverR02_RS03750	COG0583	DNA-binding transcription factor activity
PverR02_RS03755	COG0667	Aldo Keto reductase
PverR02_RS03765	COG1280	lysine exporter protein (LysE YggA)
PverR02_RS03865	COG0582	viral genome integration into host DNA
PverR02_RS03880	COG2223	nitrite transmembrane transporter activity
PverR02_RS03905	COG1157	protein secretion by the type III secretion system
PverR02_RS03930	COG4794	Type iii secretion
PverR02_RS03940	COG4792	protein secretion
PverR02_RS04005	COG0193	aminoacyl-tRNA hydrolase activity
PverR02_RS04010	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PverR02_RS04015	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PverR02_RS04025	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PverR02_RS04030	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
PverR02_RS04040	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PverR02_RS04045	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PverR02_RS04055	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PverR02_RS04060	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PverR02_RS04075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PverR02_RS04090	COG4221	oxidoreductase activity
PverR02_RS04100	COG0415	Belongs to the DNA photolyase family
PverR02_RS04105	COG0789	Transcriptional regulator
PverR02_RS04120	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
PverR02_RS04125	COG1090	epimerase
PverR02_RS04130	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PverR02_RS04140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PverR02_RS04150	COG0175	sulfate reduction
PverR02_RS04165	COG0204	Acyl-transferase
PverR02_RS04170	COG0857	belongs to the CobB CobQ family
PverR02_RS04170	COG0280	phosphate acetyltransferase
PverR02_RS04180	COG1047	Peptidyl-prolyl cis-trans
PverR02_RS04185	COG0268	Binds directly to 16S ribosomal RNA
PverR02_RS04200	COG0196	riboflavin kinase activity
PverR02_RS04205	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PverR02_RS04210	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PverR02_RS04215	COG1047	Peptidyl-prolyl cis-trans
PverR02_RS04220	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PverR02_RS04245	COG2165	general secretion pathway protein
PverR02_RS04250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PverR02_RS04275	COG0542	response to heat
PverR02_RS04300	COG1252	NADH dehydrogenase
PverR02_RS04320	COG3622	Belongs to the hyi family
PverR02_RS04340	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
PverR02_RS04345	COG0237	dephospho-CoA kinase activity
PverR02_RS04350	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PverR02_RS04390	COG3023	N-Acetylmuramoyl-L-alanine amidase
PverR02_RS04410	COG0084	hydrolase, TatD family'
PverR02_RS04415	COG1609	Transcriptional regulator
PverR02_RS04425	COG1105	Belongs to the carbohydrate kinase PfkB family
PverR02_RS04430	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
PverR02_RS04430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PverR02_RS04430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PverR02_RS04440	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PverR02_RS04445	COG4774	siderophore transport
PverR02_RS04450	COG3128	pkhd-type hydroxylase
PverR02_RS04460	COG0019	diaminopimelate decarboxylase activity
PverR02_RS04485	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PverR02_RS04495	COG1131	(ABC) transporter
PverR02_RS04515	COG4608	Belongs to the ABC transporter superfamily
PverR02_RS04520	COG0444	Belongs to the ABC transporter superfamily
PverR02_RS04525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PverR02_RS04530	COG0601	transmembrane transport
PverR02_RS04535	COG0747	negative chemotaxis
PverR02_RS04545	COG0747	negative chemotaxis
PverR02_RS04550	COG0747	negative chemotaxis
PverR02_RS04555	COG0747	negative chemotaxis
PverR02_RS04575	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
PverR02_RS04580	COG4178	(ABC) transporter
PverR02_RS04595	COG0180	Tryptophanyl-tRNA synthetase
PverR02_RS04600	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PverR02_RS04610	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS04615	COG0667	Aldo Keto reductase
PverR02_RS04620	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PverR02_RS04625	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PverR02_RS04630	COG0723	plastoquinol--plastocyanin reductase activity
PverR02_RS04635	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PverR02_RS04640	COG2857	Cytochrome c1
PverR02_RS04645	COG0625	glutathione transferase activity
PverR02_RS04650	COG2969	positive regulation of protein catabolic process
PverR02_RS04655	COG2186	Transcriptional regulator
PverR02_RS04675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PverR02_RS04685	COG2271	Major facilitator Superfamily
PverR02_RS04690	COG2721	sulfolactate sulfo-lyase activity
PverR02_RS04700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PverR02_RS04710	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PverR02_RS04715	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PverR02_RS04720	COG0154	amidase activity
PverR02_RS04725	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PverR02_RS04730	COG1077	Cell shape determining protein MreB Mrl
PverR02_RS04735	COG1792	Involved in formation and maintenance of cell shape
PverR02_RS04745	COG0424	maF-like protein
PverR02_RS04750	COG1530	ribonuclease E activity
PverR02_RS04760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PverR02_RS04765	COG0312	modulator of DNA gyrase
PverR02_RS04770	COG3028	Belongs to the UPF0307 family
PverR02_RS04775	COG0312	modulator of DNA gyrase
PverR02_RS04810	COG1660	Displays ATPase and GTPase activities
PverR02_RS04820	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PverR02_RS04825	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PverR02_RS04830	COG1137	ATPase activity
PverR02_RS04835	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
PverR02_RS04845	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PverR02_RS04855	COG1127	ABC transporter
PverR02_RS04860	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PverR02_RS04865	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PverR02_RS04885	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PverR02_RS04890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PverR02_RS04895	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PverR02_RS04900	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PverR02_RS04910	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PverR02_RS04915	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PverR02_RS04975	COG2135	peptidase activity
PverR02_RS04980	COG0501	Belongs to the peptidase M48B family
PverR02_RS04985	COG2119	membrane
PverR02_RS04990	COG2813	Specifically methylates the guanine in position
PverR02_RS04995	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PverR02_RS05000	COG1280	lysine exporter protein (LysE YggA)
PverR02_RS05005	COG0318	PFAM AMP-dependent synthetase and ligase
PverR02_RS05025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PverR02_RS05035	COG2823	Periplasmic or secreted lipoprotein
PverR02_RS05040	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PverR02_RS05045	COG0792	nuclease activity
PverR02_RS05065	COG2001	Belongs to the MraZ family
PverR02_RS05070	COG0275	rRNA processing
PverR02_RS05085	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PverR02_RS05090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PverR02_RS05095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PverR02_RS05100	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PverR02_RS05105	COG0772	Belongs to the SEDS family
PverR02_RS05110	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PverR02_RS05115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PverR02_RS05120	COG1181	Belongs to the D-alanine--D-alanine ligase family
PverR02_RS05135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PverR02_RS05140	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PverR02_RS05145	COG2203	Gaf domain
PverR02_RS05145	COG3706	GGDEF domain
PverR02_RS05145	COG4251	negative regulation of phosphorylation
PverR02_RS05145	COG5001	Diguanylate cyclase
PverR02_RS05155	COG5002	protein histidine kinase activity
PverR02_RS05180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PverR02_RS05195	COG0835	chemotaxis
PverR02_RS05195	COG0784	Response regulator, receiver
PverR02_RS05205	COG0583	DNA-binding transcription factor activity
PverR02_RS05225	COG1566	PFAM secretion protein HlyD family protein
PverR02_RS05235	COG0577	efflux transmembrane transporter activity
PverR02_RS05235	COG1136	(ABC) transporter
PverR02_RS05255	COG0300	oxidoreductase activity
PverR02_RS05265	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
PverR02_RS05265	COG0662	Cupin 2, conserved barrel domain protein
PverR02_RS05280	COG1696	Membrane protein involved in D-alanine export
PverR02_RS05295	COG3420	alginic acid biosynthetic process
PverR02_RS05305	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
PverR02_RS05310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PverR02_RS05320	COG1215	transferase activity, transferring glycosyl groups
PverR02_RS05330	COG3022	response to hydroperoxide
PverR02_RS05340	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PverR02_RS05345	COG0315	cyclic pyranopterin monophosphate synthase activity
PverR02_RS05350	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PverR02_RS05360	COG0513	Belongs to the DEAD box helicase family
PverR02_RS05365	COG0400	carboxylic ester hydrolase activity
PverR02_RS05370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PverR02_RS05375	COG4597	amino acid ABC transporter
PverR02_RS05380	COG0765	amino acid transport
PverR02_RS05385	COG1126	abc transporter atp-binding protein
PverR02_RS05400	COG2186	Transcriptional regulator
PverR02_RS05405	COG2807	transmembrane transport
PverR02_RS05420	COG3188	usher protein
PverR02_RS05425	COG3121	Chaperone
PverR02_RS05460	COG3539	Fimbrial protein
PverR02_RS05470	COG2827	Endonuclease containing a URI domain
PverR02_RS05480	COG4774	siderophore transport
PverR02_RS05485	COG2027	D-alanyl-D-alanine carboxypeptidase
PverR02_RS05495	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
PverR02_RS05500	COG0179	Fumarylacetoacetate (FAA) hydrolase
PverR02_RS05515	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PverR02_RS05565	COG0477	Major facilitator Superfamily
PverR02_RS05570	COG0583	DNA-binding transcription factor activity
PverR02_RS05600	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PverR02_RS05605	COG3081	Nucleoid-associated protein
PverR02_RS05615	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
PverR02_RS05620	COG0525	valine-tRNA ligase activity
PverR02_RS05635	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PverR02_RS05640	COG0795	lipopolysaccharide-transporting ATPase activity
PverR02_RS05645	COG0795	lipopolysaccharide-transporting ATPase activity
PverR02_RS05650	COG0481	GTPase activity
PverR02_RS05655	COG0681	Belongs to the peptidase S26 family
PverR02_RS05660	COG0571	ribonuclease III activity
PverR02_RS05665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PverR02_RS05670	COG1381	Involved in DNA repair and RecF pathway recombination
PverR02_RS05675	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PverR02_RS05685	COG0590	tRNA wobble adenosine to inosine editing
PverR02_RS05690	COG0500	methyltransferase
PverR02_RS05695	COG2226	methyltransferase
PverR02_RS05710	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PverR02_RS05735	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS05740	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS05755	COG0523	cobalamin synthesis protein
PverR02_RS05770	COG4206	TonB-dependent receptor
PverR02_RS05775	COG4628	conserved protein (DUF2132)
PverR02_RS05785	COG2375	cellular response to nickel ion
PverR02_RS05790	COG1695	Transcriptional regulator
PverR02_RS05840	COG1113	amino acid transport
PverR02_RS05855	COG2246	polysaccharide biosynthetic process
PverR02_RS05870	COG0069	glutamate synthase activity
PverR02_RS05885	COG4191	Histidine kinase
PverR02_RS05890	COG1858	cytochrome C peroxidase
PverR02_RS05910	COG0583	DNA-binding transcription factor activity
PverR02_RS05925	COG2267	carboxylic ester hydrolase activity
PverR02_RS05945	COG2076	Multidrug Resistance protein
PverR02_RS05960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PverR02_RS05975	COG4191	Histidine kinase
PverR02_RS05980	COG2204	response regulator
PverR02_RS06000	COG1126	abc transporter atp-binding protein
PverR02_RS06005	COG0765	amino acid transport
PverR02_RS06010	COG0765	amino acid transport
PverR02_RS06015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PverR02_RS06030	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PverR02_RS06040	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PverR02_RS06045	COG3842	ATPase activity
PverR02_RS06050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PverR02_RS06060	COG0243	molybdopterin cofactor binding
PverR02_RS06065	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
PverR02_RS06080	COG0450	alkyl hydroperoxide reductase
PverR02_RS06090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PverR02_RS06095	COG0418	dihydroorotase activity
PverR02_RS06105	COG0137	argininosuccinate synthase activity
PverR02_RS06110	COG2197	response regulator
PverR02_RS06120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PverR02_RS06135	COG4658	electron transport chain
PverR02_RS06140	COG2878	Part of a membrane complex involved in electron transport
PverR02_RS06150	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PverR02_RS06150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PverR02_RS06155	COG0489	protein tyrosine kinase activity
PverR02_RS06165	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PverR02_RS06255	COG3179	chitinase
PverR02_RS06265	COG1546	Belongs to the CinA family
PverR02_RS06275	COG2137	regulation of response to DNA damage stimulus
PverR02_RS06290	COG3148	PFAM DTW domain containing protein
PverR02_RS06305	COG0583	DNA-binding transcription factor activity
PverR02_RS06320	COG4807	Protein conserved in bacteria
PverR02_RS06335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PverR02_RS06340	COG3158	transport of potassium into the cell
PverR02_RS06345	COG1902	pentaerythritol trinitrate reductase activity
PverR02_RS06355	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
PverR02_RS06360	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS06365	COG1177	transmembrane transport
PverR02_RS06370	COG1176	ABC-type spermidine putrescine transport system, permease component I
PverR02_RS06375	COG3842	ATPase activity
PverR02_RS06380	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PverR02_RS06390	COG0583	DNA-binding transcription factor activity
PverR02_RS06425	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PverR02_RS06425	COG0457	Tetratricopeptide repeat
PverR02_RS06440	COG2201	protein-glutamate methylesterase activity
PverR02_RS06445	COG5001	Diguanylate cyclase
PverR02_RS06445	COG2203	Gaf domain
PverR02_RS06445	COG3706	GGDEF domain
PverR02_RS06445	COG4251	negative regulation of phosphorylation
PverR02_RS06455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PverR02_RS06475	COG1073	alpha beta
PverR02_RS06490	COG2885	chlorophyll binding
PverR02_RS06505	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PverR02_RS06510	COG0563	adenylate kinase activity
PverR02_RS06515	COG1214	PFAM Peptidase M22, glycoprotease
PverR02_RS06525	COG1801	Protein of unknown function DUF72
PverR02_RS06540	COG0742	ribosomal rna small subunit methyltransferase
PverR02_RS06550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PverR02_RS06555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PverR02_RS06560	COG1522	sequence-specific DNA binding
PverR02_RS06580	COG3126	Type III secretion system lipoprotein chaperone (YscW)
PverR02_RS06585	COG2937	Belongs to the GPAT DAPAT family
PverR02_RS06600	COG2226	methyltransferase
PverR02_RS06605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PverR02_RS06610	COG1215	transferase activity, transferring glycosyl groups
PverR02_RS06615	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
PverR02_RS06620	COG2166	iron-sulfur cluster assembly
PverR02_RS06625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PverR02_RS06630	COG2171	N-acyltransferase activity
PverR02_RS06635	COG1393	Belongs to the ArsC family
PverR02_RS06640	COG0025	NhaP-type Na H and K H
PverR02_RS06660	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PverR02_RS06665	COG0024	Methionine aminopeptidase
PverR02_RS06670	COG0052	Belongs to the universal ribosomal protein uS2 family
PverR02_RS06675	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PverR02_RS06680	COG0528	UMP kinase activity
PverR02_RS06685	COG0233	cytoplasmic translational termination
PverR02_RS06690	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PverR02_RS06700	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PverR02_RS06720	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PverR02_RS06725	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PverR02_RS06730	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PverR02_RS06735	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PverR02_RS06740	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PverR02_RS06745	COG0587	DNA-directed DNA polymerase activity
PverR02_RS06750	COG0825	malonyl-CoA metabolic process
PverR02_RS06755	COG0037	tRNA processing
PverR02_RS06760	COG0504	CTP synthase activity
PverR02_RS06765	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PverR02_RS06770	COG0148	phosphopyruvate hydratase activity
PverR02_RS06780	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
PverR02_RS06790	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
PverR02_RS06795	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PverR02_RS06800	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PverR02_RS06805	COG0585	pseudouridine synthase activity
PverR02_RS06810	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PverR02_RS06815	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PverR02_RS06830	COG1278	Cold shock
PverR02_RS06835	COG0717	Belongs to the dCTP deaminase family
PverR02_RS06870	COG2366	antibiotic biosynthetic process
PverR02_RS06875	COG0653	protein targeting
PverR02_RS06885	COG3012	SEC-C Motif Domain Protein
PverR02_RS06910	COG1199	ATP-dependent helicase activity
PverR02_RS06930	COG0259	pyridoxamine-phosphate oxidase activity
PverR02_RS06945	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PverR02_RS06955	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
PverR02_RS06970	COG0583	DNA-binding transcription factor activity
PverR02_RS06985	COG3220	belongs to the UPF0276 family
PverR02_RS07045	COG2271	Major facilitator Superfamily
PverR02_RS07050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PverR02_RS07070	COG0583	DNA-binding transcription factor activity
PverR02_RS07075	COG0306	phosphate transporter
PverR02_RS07085	COG1414	Transcriptional regulator
PverR02_RS07090	COG2814	Major facilitator Superfamily
PverR02_RS07095	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PverR02_RS07100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PverR02_RS07105	COG0183	Belongs to the thiolase family
PverR02_RS07110	COG3485	protocatechuate 3,4-dioxygenase
PverR02_RS07115	COG3485	protocatechuate 3,4-dioxygenase
PverR02_RS07120	COG0477	Major facilitator Superfamily
PverR02_RS07130	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PverR02_RS07135	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PverR02_RS07170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PverR02_RS07175	COG1309	transcriptional regulator
PverR02_RS07180	COG1902	pentaerythritol trinitrate reductase activity
PverR02_RS07185	COG2814	Major facilitator Superfamily
PverR02_RS07225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PverR02_RS07235	COG1704	LemA family
PverR02_RS07255	COG0697	spore germination
PverR02_RS07260	COG0693	protein deglycase activity
PverR02_RS07270	COG1629	transport
PverR02_RS07280	COG1595	DNA-templated transcription, initiation
PverR02_RS07290	COG1454	alcohol dehydrogenase
PverR02_RS07295	COG2814	Major facilitator Superfamily
PverR02_RS07300	COG0156	8-amino-7-oxononanoate synthase activity
PverR02_RS07335	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PverR02_RS07350	COG0583	DNA-binding transcription factor activity
PverR02_RS07355	COG2814	Major facilitator Superfamily
PverR02_RS07390	COG0701	Predicted permease
PverR02_RS07405	COG0431	NADPH-dependent FMN reductase
PverR02_RS07410	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PverR02_RS07415	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PverR02_RS07420	COG0640	Transcriptional regulator
PverR02_RS07440	COG2267	carboxylic ester hydrolase activity
PverR02_RS07455	COG0439	Biotin carboxylase
PverR02_RS07470	COG3842	ATPase activity
PverR02_RS07500	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PverR02_RS07555	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
PverR02_RS07585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PverR02_RS07595	COG0425	Belongs to the sulfur carrier protein TusA family
PverR02_RS07605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PverR02_RS07615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PverR02_RS07620	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
PverR02_RS07625	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PverR02_RS07630	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PverR02_RS07645	COG4680	protein conserved in bacteria
PverR02_RS07670	COG2200	EAL domain
PverR02_RS07670	COG2199	diguanylate cyclase activity
PverR02_RS07670	COG2202	Pas domain
PverR02_RS07680	COG0583	DNA-binding transcription factor activity
PverR02_RS07685	COG0477	Major facilitator Superfamily
PverR02_RS07715	COG0583	DNA-binding transcription factor activity
PverR02_RS07730	COG1802	Transcriptional regulator
PverR02_RS07735	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS07740	COG3246	L-lysine catabolic process to acetate
PverR02_RS07780	COG2807	transmembrane transport
PverR02_RS07785	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS07795	COG0583	DNA-binding transcription factor activity
PverR02_RS07800	COG2910	NAD(P)H-binding
PverR02_RS07810	COG0583	DNA-binding transcription factor activity
PverR02_RS07840	COG0174	glutamine synthetase
PverR02_RS07855	COG3100	YcgL domain-containing protein
PverR02_RS07870	COG2983	Belongs to the UPF0260 family
PverR02_RS07905	COG1770	oligopeptidase
PverR02_RS07915	COG0121	glutamine amidotransferase
PverR02_RS07925	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PverR02_RS07935	COG0542	response to heat
PverR02_RS07940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PverR02_RS07955	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
PverR02_RS07960	COG0425	Belongs to the sulfur carrier protein TusA family
PverR02_RS07970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PverR02_RS07980	COG1132	(ABC) transporter
PverR02_RS07985	COG0741	lytic transglycosylase activity
PverR02_RS07990	COG0488	(ABC) transporter
PverR02_RS07995	COG0589	response to stress
PverR02_RS08005	COG1250	3-hydroxyacyl-CoA dehydrogenase
PverR02_RS08005	COG1024	Enoyl-CoA hydratase
PverR02_RS08010	COG0183	Belongs to the thiolase family
PverR02_RS08055	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PverR02_RS08065	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PverR02_RS08075	COG1477	protein flavinylation
PverR02_RS08080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PverR02_RS08085	COG0584	glycerophosphoryl diester phosphodiesterase
PverR02_RS08095	COG4591	ABC-type transport system involved in lipoprotein release permease component
PverR02_RS08100	COG1136	(ABC) transporter
PverR02_RS08105	COG4591	ABC-type transport system involved in lipoprotein release permease component
PverR02_RS08125	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PverR02_RS08125	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PverR02_RS08130	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PverR02_RS08130	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PverR02_RS08145	COG2853	Lipoprotein
PverR02_RS08155	COG2204	response regulator
PverR02_RS08165	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PverR02_RS08170	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PverR02_RS08380	COG4695	Portal protein
PverR02_RS08435	COG0579	oxidoreductase
PverR02_RS08445	COG0583	DNA-binding transcription factor activity
PverR02_RS08465	COG1611	Belongs to the LOG family
PverR02_RS08475	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PverR02_RS08485	COG0583	DNA-binding transcription factor activity
PverR02_RS08490	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PverR02_RS08495	COG0583	DNA-binding transcription factor activity
PverR02_RS08500	COG2814	Major facilitator Superfamily
PverR02_RS08510	COG2233	PERMEase
PverR02_RS08515	COG2267	carboxylic ester hydrolase activity
PverR02_RS08520	COG2197	response regulator
PverR02_RS08525	COG0596	Alpha beta hydrolase
PverR02_RS08535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PverR02_RS08540	COG0444	Belongs to the ABC transporter superfamily
PverR02_RS08550	COG0747	negative chemotaxis
PverR02_RS08555	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS08560	COG0546	phosphoglycolate phosphatase activity
PverR02_RS08565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PverR02_RS08570	COG0402	S-adenosylhomocysteine deaminase activity
PverR02_RS08575	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PverR02_RS08585	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PverR02_RS08595	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PverR02_RS08600	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PverR02_RS08605	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PverR02_RS08620	COG0776	regulation of translation
PverR02_RS08645	COG1216	Glycosyl transferase, family 2
PverR02_RS08655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PverR02_RS08665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PverR02_RS08670	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS08680	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PverR02_RS08685	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PverR02_RS08690	COG0546	phosphoglycolate phosphatase activity
PverR02_RS08690	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PverR02_RS08715	COG0493	'glutamate synthase
PverR02_RS08715	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
PverR02_RS08730	COG1555	photosystem II stabilization
PverR02_RS08760	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
PverR02_RS08770	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
PverR02_RS08775	COG2205	protein histidine kinase activity
PverR02_RS08780	COG0745	RESPONSE REGULATOR receiver
PverR02_RS08815	COG0084	hydrolase, TatD family'
PverR02_RS08820	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PverR02_RS08825	COG2259	Doxx family
PverR02_RS08845	COG1131	(ABC) transporter
PverR02_RS08855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PverR02_RS08860	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
PverR02_RS08865	COG4181	ATPase activity
PverR02_RS08880	COG1376	ErfK ybiS ycfS ynhG family protein
PverR02_RS08910	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PverR02_RS08930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PverR02_RS08945	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PverR02_RS08950	COG1764	response to oxidative stress
PverR02_RS08955	COG1846	Transcriptional regulator
PverR02_RS08960	COG0583	DNA-binding transcription factor activity
PverR02_RS08965	COG0730	response to heat
PverR02_RS08970	COG0583	DNA-binding transcription factor activity
PverR02_RS08980	COG3214	Protein conserved in bacteria
PverR02_RS08985	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PverR02_RS08995	COG1024	Enoyl-CoA hydratase
PverR02_RS09000	COG0513	Belongs to the DEAD box helicase family
PverR02_RS09010	COG3384	dioxygenase
PverR02_RS09015	COG0500	methyltransferase
PverR02_RS09020	COG0501	Belongs to the peptidase M48B family
PverR02_RS09025	COG0436	Aminotransferase
PverR02_RS09030	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PverR02_RS09035	COG0386	Belongs to the glutathione peroxidase family
PverR02_RS09040	COG1846	Transcriptional regulator
PverR02_RS09045	COG5002	protein histidine kinase activity
PverR02_RS09045	COG2205	protein histidine kinase activity
PverR02_RS09045	COG0784	Response regulator, receiver
PverR02_RS09055	COG1956	GAF domain-containing protein
PverR02_RS09060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PverR02_RS09060	COG2205	protein histidine kinase activity
PverR02_RS09065	COG2197	response regulator
PverR02_RS09100	COG0004	ammonium transporteR
PverR02_RS09130	COG0746	molybdenum cofactor guanylyltransferase activity
PverR02_RS09135	COG0521	Mo-molybdopterin cofactor biosynthetic process
PverR02_RS09140	COG0303	'Molybdopterin
PverR02_RS09145	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PverR02_RS09155	COG4133	protoheme IX ABC transporter activity
PverR02_RS09175	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
PverR02_RS09180	COG1138	Cytochrome C-type biogenesis protein
PverR02_RS09190	COG3088	subunit of a heme lyase
PverR02_RS09195	COG4235	cytochrome complex assembly
PverR02_RS09225	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
PverR02_RS09230	COG0583	DNA-binding transcription factor activity
PverR02_RS09240	COG2814	Major facilitator Superfamily
PverR02_RS09245	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
PverR02_RS09250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PverR02_RS09265	COG2084	Dehydrogenase
PverR02_RS09270	COG3622	Belongs to the hyi family
PverR02_RS09275	COG3960	tartronate-semialdehyde synthase activity
PverR02_RS09285	COG1309	transcriptional regulator
PverR02_RS09290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PverR02_RS09305	COG1126	abc transporter atp-binding protein
PverR02_RS09310	COG2853	Lipoprotein
PverR02_RS09330	COG2113	Glycine betaine
PverR02_RS09335	COG3162	membrane
PverR02_RS09350	COG2009	succinate dehydrogenase
PverR02_RS09355	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
PverR02_RS09360	COG1053	succinate dehydrogenase
PverR02_RS09365	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PverR02_RS09380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PverR02_RS09385	COG0045	succinate-CoA ligase (ADP-forming) activity
PverR02_RS09420	COG0326	Molecular chaperone. Has ATPase activity
PverR02_RS09430	COG1741	Belongs to the pirin family
PverR02_RS09445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PverR02_RS09450	COG5002	protein histidine kinase activity
PverR02_RS09450	COG2205	protein histidine kinase activity
PverR02_RS09450	COG0784	Response regulator, receiver
PverR02_RS09465	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PverR02_RS09480	COG1022	Amp-dependent synthetase and ligase
PverR02_RS09505	COG0628	permease
PverR02_RS09520	COG0284	orotidine-5'-phosphate decarboxylase activity
PverR02_RS09525	COG2130	NADP-dependent
PverR02_RS09540	COG0840	transmembrane signaling receptor activity
PverR02_RS09545	COG2267	carboxylic ester hydrolase activity
PverR02_RS09575	COG0318	PFAM AMP-dependent synthetase and ligase
PverR02_RS09580	COG4191	Histidine kinase
PverR02_RS09585	COG4566	intracellular signal transduction
PverR02_RS09590	COG1309	transcriptional regulator
PverR02_RS09595	COG1250	3-hydroxyacyl-CoA dehydrogenase
PverR02_RS09610	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS09615	COG0427	acetyl-CoA hydrolase
PverR02_RS09630	COG0811	peptide transport
PverR02_RS09650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PverR02_RS09655	COG3540	Alkaline phosphatase
PverR02_RS09675	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS09685	COG0625	glutathione transferase activity
PverR02_RS09690	COG1131	(ABC) transporter
PverR02_RS09695	COG0842	Transport permease protein
PverR02_RS09715	COG0477	Major facilitator Superfamily
PverR02_RS09725	COG2076	Multidrug Resistance protein
PverR02_RS09730	COG0385	Bile acid
PverR02_RS09735	COG2974	May be involved in recombination
PverR02_RS09755	COG1053	succinate dehydrogenase
PverR02_RS09765	COG1053	succinate dehydrogenase
PverR02_RS09770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PverR02_RS09780	COG1053	succinate dehydrogenase
PverR02_RS09795	COG0583	DNA-binding transcription factor activity
PverR02_RS09800	COG3485	protocatechuate 3,4-dioxygenase
PverR02_RS09805	COG3485	protocatechuate 3,4-dioxygenase
PverR02_RS09820	COG0582	viral genome integration into host DNA
PverR02_RS09825	COG1846	Transcriptional regulator
PverR02_RS09835	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS09865	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PverR02_RS09875	COG0411	ABC transporter
PverR02_RS09890	COG0154	amidase activity
PverR02_RS09895	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS09910	COG4638	Rieske (2fe-2S)
PverR02_RS09920	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS09930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PverR02_RS09980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PverR02_RS09985	COG0747	negative chemotaxis
PverR02_RS09990	COG0601	transmembrane transport
PverR02_RS09995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PverR02_RS10015	COG2022	thiamine diphosphate biosynthetic process
PverR02_RS10015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PverR02_RS10030	COG0473	3-isopropylmalate dehydrogenase activity
PverR02_RS10035	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PverR02_RS10050	COG1522	sequence-specific DNA binding
PverR02_RS10085	COG0477	Major facilitator Superfamily
PverR02_RS10090	COG0583	DNA-binding transcription factor activity
PverR02_RS10095	COG0745	RESPONSE REGULATOR receiver
PverR02_RS10100	COG2205	protein histidine kinase activity
PverR02_RS10105	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
PverR02_RS10110	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
PverR02_RS10115	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
PverR02_RS10130	COG2010	Cytochrome c
PverR02_RS10135	COG0545	Peptidyl-prolyl cis-trans isomerase
PverR02_RS10155	COG2200	EAL domain
PverR02_RS10165	COG3321	synthase
PverR02_RS10165	COG4221	oxidoreductase activity
PverR02_RS10165	COG0604	alcohol dehydrogenase
PverR02_RS10165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PverR02_RS10175	COG3842	ATPase activity
PverR02_RS10185	COG1176	ABC-type spermidine putrescine transport system, permease component I
PverR02_RS10210	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PverR02_RS10215	COG1121	(ABC) transporter
PverR02_RS10260	COG3829	transcription factor binding
PverR02_RS10270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PverR02_RS10275	COG0431	NADPH-dependent FMN reductase
PverR02_RS10300	COG5006	permease, DMT superfamily
PverR02_RS10340	COG0768	penicillin binding
PverR02_RS10355	COG0417	DNA replication proofreading
PverR02_RS10385	COG4977	sequence-specific DNA binding
PverR02_RS10390	COG0596	Alpha beta hydrolase
PverR02_RS10395	COG3387	PFAM Glycoside hydrolase 15-related
PverR02_RS10400	COG0583	DNA-binding transcription factor activity
PverR02_RS10405	COG2828	Protein conserved in bacteria
PverR02_RS10410	COG1301	dicarboxylic acid transport
PverR02_RS10415	COG2851	Citrate transporter
PverR02_RS10445	COG0583	DNA-binding transcription factor activity
PverR02_RS10455	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS10470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PverR02_RS10475	COG0765	amino acid transport
PverR02_RS10495	COG0840	transmembrane signaling receptor activity
PverR02_RS10510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PverR02_RS10525	COG0028	Belongs to the TPP enzyme family
PverR02_RS10530	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS10535	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS10560	COG3971	2-oxopent-4-enoate hydratase activity
PverR02_RS10585	COG5002	protein histidine kinase activity
PverR02_RS10590	COG0745	RESPONSE REGULATOR receiver
PverR02_RS10610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PverR02_RS10635	COG3852	Histidine kinase
PverR02_RS10645	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PverR02_RS10650	COG0835	chemotaxis
PverR02_RS10655	COG0840	transmembrane signaling receptor activity
PverR02_RS10675	COG0840	transmembrane signaling receptor activity
PverR02_RS10690	COG0643	Histidine kinase
PverR02_RS10690	COG2198	Histidine kinase
PverR02_RS10695	COG0840	transmembrane signaling receptor activity
PverR02_RS10705	COG0835	chemotaxis
PverR02_RS10715	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
PverR02_RS10720	COG2201	protein-glutamate methylesterase activity
PverR02_RS10735	COG2223	nitrite transmembrane transporter activity
PverR02_RS10745	COG0402	S-adenosylhomocysteine deaminase activity
PverR02_RS10755	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PverR02_RS10760	COG1051	belongs to the nudix hydrolase family
PverR02_RS10765	COG0720	synthase
PverR02_RS10795	COG0840	transmembrane signaling receptor activity
PverR02_RS10800	COG2056	Na+-H+ antiporter family
PverR02_RS10810	COG0826	peptidase U32
PverR02_RS10815	COG0628	permease
PverR02_RS10830	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PverR02_RS10835	COG3132	Protein of unknown function, DUF480
PverR02_RS10850	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PverR02_RS10860	COG0583	DNA-binding transcription factor activity
PverR02_RS10870	COG1253	flavin adenine dinucleotide binding
PverR02_RS10875	COG0709	Synthesizes selenophosphate from selenide and ATP
PverR02_RS10880	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
PverR02_RS10885	COG0701	Predicted permease
PverR02_RS10895	COG0625	glutathione transferase activity
PverR02_RS10900	COG0384	phenazine biosynthesis protein PhzF
PverR02_RS10905	COG0113	porphobilinogen synthase activity
PverR02_RS10910	COG1280	lysine exporter protein (LysE YggA)
PverR02_RS10935	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PverR02_RS10940	COG0583	DNA-binding transcription factor activity
PverR02_RS10950	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PverR02_RS10955	COG0517	IMP dehydrogenase activity
PverR02_RS10960	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PverR02_RS10985	COG4335	DNA alkylation repair
PverR02_RS10990	COG0174	glutamine synthetase
PverR02_RS11000	COG2814	Major facilitator Superfamily
PverR02_RS11040	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PverR02_RS11050	COG2197	response regulator
PverR02_RS11055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PverR02_RS11055	COG2205	protein histidine kinase activity
PverR02_RS11065	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PverR02_RS11070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PverR02_RS11090	COG2197	response regulator
PverR02_RS11095	COG0322	excinuclease ABC activity
PverR02_RS11110	COG0582	viral genome integration into host DNA
PverR02_RS11165	COG1802	Transcriptional regulator
PverR02_RS11170	COG0277	FAD linked oxidase domain protein
PverR02_RS11195	COG2814	Major facilitator Superfamily
PverR02_RS11200	COG1414	Transcriptional regulator
PverR02_RS11305	COG3436	PFAM IS66 Orf2 family protein
PverR02_RS11315	COG3012	SEC-C Motif Domain Protein
PverR02_RS11365	COG2003	Belongs to the UPF0758 family
PverR02_RS11380	COG3620	sequence-specific DNA binding
PverR02_RS11390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PverR02_RS11450	COG1473	amidohydrolase
PverR02_RS11455	COG0583	DNA-binding transcription factor activity
PverR02_RS11495	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS11540	COG0583	DNA-binding transcription factor activity
PverR02_RS11550	COG0583	DNA-binding transcription factor activity
PverR02_RS11570	COG1566	PFAM secretion protein HlyD family protein
PverR02_RS11575	COG1522	sequence-specific DNA binding
PverR02_RS11580	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PverR02_RS11585	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS11590	COG2113	Glycine betaine
PverR02_RS11595	COG4176	ABC-type proline glycine betaine transport system permease component
PverR02_RS11600	COG0517	IMP dehydrogenase activity
PverR02_RS11600	COG4175	Glycine betaine
PverR02_RS11615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PverR02_RS11620	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS11635	COG3835	regulator
PverR02_RS11685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PverR02_RS11690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PverR02_RS11695	COG4569	acetaldehyde dehydrogenase (acetylating) activity
PverR02_RS11705	COG0477	Major facilitator Superfamily
PverR02_RS11720	COG0477	Major facilitator Superfamily
PverR02_RS11725	COG1024	Enoyl-CoA hydratase
PverR02_RS11730	COG1024	Enoyl-CoA hydratase
PverR02_RS11735	COG0183	Belongs to the thiolase family
PverR02_RS11745	COG2030	dehydratase
PverR02_RS11760	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS11765	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS11770	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS11775	COG1053	succinate dehydrogenase
PverR02_RS11800	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS11815	COG2267	carboxylic ester hydrolase activity
PverR02_RS11825	COG0346	lactoylglutathione lyase activity
PverR02_RS11850	COG3573	Dehydrogenase
PverR02_RS11875	COG0583	DNA-binding transcription factor activity
PverR02_RS11900	COG1733	regulation of RNA biosynthetic process
PverR02_RS11905	COG0604	alcohol dehydrogenase
PverR02_RS11965	COG1902	pentaerythritol trinitrate reductase activity
PverR02_RS11965	COG0446	pyridine nucleotide-disulphide oxidoreductase
PverR02_RS11990	COG3448	diguanylate cyclase activity
PverR02_RS11990	COG4175	Glycine betaine
PverR02_RS11995	COG4176	ABC-type proline glycine betaine transport system permease component
PverR02_RS12005	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PverR02_RS12020	COG2113	Glycine betaine
PverR02_RS12050	COG0840	transmembrane signaling receptor activity
PverR02_RS12060	COG1063	alcohol dehydrogenase
PverR02_RS12085	COG0583	DNA-binding transcription factor activity
PverR02_RS12100	COG1733	regulation of RNA biosynthetic process
PverR02_RS12120	COG1064	alcohol dehydrogenase
PverR02_RS12125	COG2207	Transcriptional regulator
PverR02_RS12135	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PverR02_RS12140	COG0589	response to stress
PverR02_RS12155	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS12160	COG1064	alcohol dehydrogenase
PverR02_RS12175	COG0745	RESPONSE REGULATOR receiver
PverR02_RS12180	COG2205	protein histidine kinase activity
PverR02_RS12200	COG2853	Lipoprotein
PverR02_RS12205	COG1120	ATPase activity
PverR02_RS12210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PverR02_RS12225	COG3712	iron ion homeostasis
PverR02_RS12230	COG1595	DNA-templated transcription, initiation
PverR02_RS12235	COG2814	Major facilitator Superfamily
PverR02_RS12240	COG4774	siderophore transport
PverR02_RS12260	COG1309	transcriptional regulator
PverR02_RS12285	COG2814	Major facilitator Superfamily
PverR02_RS12305	COG1024	Enoyl-CoA hydratase
PverR02_RS12310	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS12325	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS12345	COG0583	DNA-binding transcription factor activity
PverR02_RS12380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PverR02_RS12395	COG2814	Major facilitator Superfamily
PverR02_RS12430	COG1414	Transcriptional regulator
PverR02_RS12435	COG3264	Mechanosensitive ion channel
PverR02_RS12435	COG1196	nuclear chromosome segregation
PverR02_RS12445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PverR02_RS12490	COG4214	carbohydrate transport
PverR02_RS12495	COG1129	ABC transporter
PverR02_RS12500	COG4213	ABC transporter substrate-binding protein
PverR02_RS12505	COG2115	Belongs to the xylose isomerase family
PverR02_RS12510	COG2207	Transcriptional regulator
PverR02_RS12510	COG1609	Transcriptional regulator
PverR02_RS12515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PverR02_RS12540	COG0446	pyridine nucleotide-disulphide oxidoreductase
PverR02_RS12540	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PverR02_RS12555	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PverR02_RS12575	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PverR02_RS12580	COG2218	PFAM glutamate synthase alpha subunit domain protein
PverR02_RS12585	COG0069	glutamate synthase activity
PverR02_RS12590	COG0004	ammonium transporteR
PverR02_RS12610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PverR02_RS12620	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PverR02_RS12635	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PverR02_RS12645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PverR02_RS12655	COG3850	Histidine kinase
PverR02_RS12660	COG2197	response regulator
PverR02_RS12685	COG3842	ATPase activity
PverR02_RS12695	COG1176	ABC-type spermidine putrescine transport system, permease component I
PverR02_RS12700	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
PverR02_RS12705	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PverR02_RS12720	COG2186	Transcriptional regulator
PverR02_RS12725	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PverR02_RS12735	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS12740	COG2267	carboxylic ester hydrolase activity
PverR02_RS12755	COG3781	membrane
PverR02_RS12770	COG0640	Transcriptional regulator
PverR02_RS12775	COG1902	pentaerythritol trinitrate reductase activity
PverR02_RS12800	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS12810	COG1879	ABC-type sugar transport system periplasmic component
PverR02_RS12815	COG1129	ABC transporter
PverR02_RS12820	COG1172	Belongs to the binding-protein-dependent transport system permease family
PverR02_RS12825	COG2207	Transcriptional regulator
PverR02_RS12840	COG2814	Major facilitator Superfamily
PverR02_RS12860	COG1116	anion transmembrane transporter activity
PverR02_RS12885	COG1741	Belongs to the pirin family
PverR02_RS12905	COG1917	Cupin 2, conserved barrel domain protein
PverR02_RS12905	COG4977	sequence-specific DNA binding
PverR02_RS12920	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PverR02_RS12925	COG1335	isochorismatase
PverR02_RS12930	COG0583	DNA-binding transcription factor activity
PverR02_RS12940	COG5001	Diguanylate cyclase
PverR02_RS12940	COG3447	MASE1 domain protein
PverR02_RS12940	COG5002	protein histidine kinase activity
PverR02_RS12970	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS12975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PverR02_RS12980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PverR02_RS12985	COG3209	COG3209 Rhs family protein
PverR02_RS13000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PverR02_RS13010	COG0583	DNA-binding transcription factor activity
PverR02_RS13025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PverR02_RS13030	COG3206	protein involved in exopolysaccharide biosynthesis
PverR02_RS13030	COG0489	protein tyrosine kinase activity
PverR02_RS13050	COG0438	transferase activity, transferring glycosyl groups
PverR02_RS13065	COG0110	maltose O-acetyltransferase activity
PverR02_RS13080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PverR02_RS13085	COG0297	glycogen (starch) synthase activity
PverR02_RS13090	COG1051	belongs to the nudix hydrolase family
PverR02_RS13095	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
PverR02_RS13095	COG0662	Cupin 2, conserved barrel domain protein
PverR02_RS13105	COG1596	polysaccharide export
PverR02_RS13120	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PverR02_RS13125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PverR02_RS13150	COG1464	Belongs to the NlpA lipoprotein family
PverR02_RS13160	COG2011	ABC-type metal ion transport system permease component
PverR02_RS13175	COG3706	GGDEF domain
PverR02_RS13195	COG1959	2 iron, 2 sulfur cluster binding
PverR02_RS13215	COG2186	Transcriptional regulator
PverR02_RS13265	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PverR02_RS13270	COG0583	DNA-binding transcription factor activity
PverR02_RS13295	COG2072	flavoprotein involved in K transport
PverR02_RS13315	COG1999	signal sequence binding
PverR02_RS13365	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PverR02_RS13375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PverR02_RS13390	COG1177	transmembrane transport
PverR02_RS13395	COG1176	ABC-type spermidine putrescine transport system, permease component I
PverR02_RS13400	COG3842	ATPase activity
PverR02_RS13405	COG1414	Transcriptional regulator
PverR02_RS13415	COG2202	Pas domain
PverR02_RS13415	COG2205	protein histidine kinase activity
PverR02_RS13450	COG3842	ATPase activity
PverR02_RS13470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PverR02_RS13480	COG0534	Mate efflux family protein
PverR02_RS13615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PverR02_RS13620	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PverR02_RS13640	COG0308	aminopeptidase N
PverR02_RS13655	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PverR02_RS13675	COG2194	sulfuric ester hydrolase activity
PverR02_RS13680	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
PverR02_RS13685	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PverR02_RS13690	COG0561	phosphatase activity
PverR02_RS13775	COG2233	PERMEase
PverR02_RS13795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PverR02_RS13805	COG1609	Transcriptional regulator
PverR02_RS13850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PverR02_RS13855	COG0745	RESPONSE REGULATOR receiver
PverR02_RS13860	COG2205	protein histidine kinase activity
PverR02_RS13870	COG0730	response to heat
PverR02_RS13880	COG0189	ligase activity
PverR02_RS13885	COG0598	Magnesium transport protein CorA
PverR02_RS13890	COG0024	Methionine aminopeptidase
PverR02_RS13900	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PverR02_RS13915	COG1070	Carbohydrate kinase
PverR02_RS13935	COG1175	transmembrane transport
PverR02_RS13980	COG1538	Outer membrane efflux protein
PverR02_RS13990	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS14000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PverR02_RS14005	COG0348	domain, Protein
PverR02_RS14025	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PverR02_RS14030	COG3706	GGDEF domain
PverR02_RS14035	COG0784	Response regulator, receiver
PverR02_RS14035	COG4191	Histidine kinase
PverR02_RS14045	COG2814	Major facilitator Superfamily
PverR02_RS14080	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PverR02_RS14090	COG1024	Enoyl-CoA hydratase
PverR02_RS14095	COG2816	NAD+ diphosphatase activity
PverR02_RS14100	COG0730	response to heat
PverR02_RS14125	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PverR02_RS14130	COG1595	DNA-templated transcription, initiation
PverR02_RS14145	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PverR02_RS14165	COG0840	transmembrane signaling receptor activity
PverR02_RS14170	COG1968	undecaprenyl-diphosphatase activity
PverR02_RS14185	COG0583	DNA-binding transcription factor activity
PverR02_RS14190	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PverR02_RS14205	COG0488	(ABC) transporter
PverR02_RS14220	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PverR02_RS14255	COG2133	pyrroloquinoline quinone binding
PverR02_RS14270	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PverR02_RS14280	COG2822	iron ion transport
PverR02_RS14290	COG2822	iron ion transport
PverR02_RS14295	COG0672	)-iron permease
PverR02_RS14300	COG2207	Transcriptional regulator
PverR02_RS14340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PverR02_RS14375	COG0640	Transcriptional regulator
PverR02_RS14380	COG0477	Major facilitator Superfamily
PverR02_RS14395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PverR02_RS14430	COG0411	ABC transporter
PverR02_RS14455	COG3384	dioxygenase
PverR02_RS14470	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PverR02_RS14475	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS14485	COG3971	2-oxopent-4-enoate hydratase activity
PverR02_RS14490	COG0318	PFAM AMP-dependent synthetase and ligase
PverR02_RS14490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PverR02_RS14490	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS14490	COG3321	synthase
PverR02_RS14490	COG0300	oxidoreductase activity
PverR02_RS14510	COG0840	transmembrane signaling receptor activity
PverR02_RS14520	COG1177	transmembrane transport
PverR02_RS14525	COG1176	ABC-type spermidine putrescine transport system, permease component I
PverR02_RS14530	COG3842	ATPase activity
PverR02_RS14535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PverR02_RS14540	COG0174	glutamine synthetase
PverR02_RS14545	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS14550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PverR02_RS14555	COG1917	Cupin 2, conserved barrel domain protein
PverR02_RS14555	COG1396	sequence-specific DNA binding
PverR02_RS14560	COG2909	trisaccharide binding
PverR02_RS14565	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PverR02_RS14570	COG0022	dehydrogenase e1 component
PverR02_RS14575	COG0508	dehydrogenase complex catalyzes the overall conversion of
PverR02_RS14580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PverR02_RS14590	COG2204	response regulator
PverR02_RS14595	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
PverR02_RS14615	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
PverR02_RS14620	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
PverR02_RS14625	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
PverR02_RS14630	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
PverR02_RS14635	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PverR02_RS14640	COG0298	carbon dioxide binding
PverR02_RS14645	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PverR02_RS14650	COG1773	rubredoxin
PverR02_RS14655	COG1773	rubredoxin
PverR02_RS14660	COG1773	rubredoxin
PverR02_RS14665	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
PverR02_RS14670	COG0375	protein maturation
PverR02_RS14675	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PverR02_RS14680	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
PverR02_RS14685	COG0298	carbon dioxide binding
PverR02_RS14690	COG0409	Hydrogenase expression formation protein
PverR02_RS14695	COG0309	Hydrogenase expression formation protein (HypE)
PverR02_RS14815	COG4569	acetaldehyde dehydrogenase (acetylating) activity
PverR02_RS14820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PverR02_RS14840	COG1607	acyl-coa hydrolase
PverR02_RS14880	COG0456	acetyltransferase
PverR02_RS14885	COG0318	PFAM AMP-dependent synthetase and ligase
PverR02_RS14895	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PverR02_RS14910	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PverR02_RS14915	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PverR02_RS14920	COG2194	sulfuric ester hydrolase activity
PverR02_RS14955	COG3436	PFAM IS66 Orf2 family protein
PverR02_RS14965	COG0604	alcohol dehydrogenase
PverR02_RS14965	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS14965	COG3321	synthase
PverR02_RS14975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PverR02_RS14990	COG0210	DNA helicase
PverR02_RS15010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PverR02_RS15055	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
PverR02_RS15070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PverR02_RS15070	COG1199	ATP-dependent helicase activity
PverR02_RS15080	COG2207	Transcriptional regulator
PverR02_RS15090	COG2308	Evidence 4 Homologs of previously reported genes of
PverR02_RS15105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PverR02_RS15115	COG1063	alcohol dehydrogenase
PverR02_RS15140	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS15150	COG0318	PFAM AMP-dependent synthetase and ligase
PverR02_RS15160	COG3038	cytochrome b561
PverR02_RS15170	COG1172	Belongs to the binding-protein-dependent transport system permease family
PverR02_RS15175	COG1879	ABC-type sugar transport system periplasmic component
PverR02_RS15185	COG1070	Carbohydrate kinase
PverR02_RS15190	COG1522	sequence-specific DNA binding
PverR02_RS15200	COG0826	peptidase U32
PverR02_RS15215	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PverR02_RS15225	COG0589	response to stress
PverR02_RS15245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PverR02_RS15250	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
PverR02_RS15260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PverR02_RS15275	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
PverR02_RS15290	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS15300	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PverR02_RS15305	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PverR02_RS15310	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PverR02_RS15310	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PverR02_RS15330	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PverR02_RS15340	COG0459	protein refolding
PverR02_RS15360	COG0589	response to stress
PverR02_RS15380	COG1796	DNA polymerase
PverR02_RS15380	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PverR02_RS15390	COG0071	Belongs to the small heat shock protein (HSP20) family
PverR02_RS15400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PverR02_RS15405	COG0058	SHG alpha-glucan phosphorylase activity
PverR02_RS15410	COG0297	glycogen (starch) synthase activity
PverR02_RS15415	COG0574	Belongs to the PEP-utilizing enzyme family
PverR02_RS15415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PverR02_RS15455	COG1653	transport
PverR02_RS15465	COG2072	flavoprotein involved in K transport
PverR02_RS15470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PverR02_RS15480	COG2207	Transcriptional regulator
PverR02_RS15480	COG1609	Transcriptional regulator
PverR02_RS15490	COG0745	RESPONSE REGULATOR receiver
PverR02_RS15495	COG2205	protein histidine kinase activity
PverR02_RS15505	COG2433	Pfam Transposase IS66
PverR02_RS15510	COG2207	Transcriptional regulator
PverR02_RS15515	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS15535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PverR02_RS15540	COG0583	DNA-binding transcription factor activity
PverR02_RS15550	COG1538	Outer membrane efflux protein
PverR02_RS15555	COG2814	Major facilitator Superfamily
PverR02_RS15575	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS15620	COG1021	2,3-dihydroxybenzoate-AMP ligase
PverR02_RS15630	COG2226	methyltransferase
PverR02_RS15630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
PverR02_RS15630	COG3433	isochorismatase activity
PverR02_RS15645	COG1132	(ABC) transporter
PverR02_RS15645	COG2375	cellular response to nickel ion
PverR02_RS15650	COG1132	(ABC) transporter
PverR02_RS15775	COG2197	response regulator
PverR02_RS15780	COG2326	polyphosphate kinase activity
PverR02_RS15805	COG2217	Heavy metal translocating P-type atpase
PverR02_RS15825	COG0604	alcohol dehydrogenase
PverR02_RS15840	COG0028	Belongs to the TPP enzyme family
PverR02_RS15855	COG5290	Psort location Cytoplasmic, score
PverR02_RS15885	COG0596	Alpha beta hydrolase
PverR02_RS15940	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PverR02_RS16020	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS16025	COG0583	DNA-binding transcription factor activity
PverR02_RS16050	COG2814	Major facilitator Superfamily
PverR02_RS16055	COG4974	Belongs to the 'phage' integrase family
PverR02_RS16065	COG0463	Glycosyl transferase, family 2
PverR02_RS16070	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PverR02_RS16070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PverR02_RS16075	COG0726	polysaccharide deacetylase
PverR02_RS16080	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PverR02_RS16085	COG2076	Multidrug Resistance protein
PverR02_RS16090	COG2076	Multidrug Resistance protein
PverR02_RS16115	COG2124	cytochrome p450
PverR02_RS16120	COG0657	acetylesterase activity
PverR02_RS16125	COG1024	Enoyl-CoA hydratase
PverR02_RS16130	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS16135	COG1024	Enoyl-CoA hydratase
PverR02_RS16140	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS16155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PverR02_RS16160	COG3781	membrane
PverR02_RS16170	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
PverR02_RS16185	COG0745	RESPONSE REGULATOR receiver
PverR02_RS16190	COG0784	Response regulator, receiver
PverR02_RS16190	COG2205	protein histidine kinase activity
PverR02_RS16200	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PverR02_RS16205	COG2205	protein histidine kinase activity
PverR02_RS16205	COG0784	Response regulator, receiver
PverR02_RS16205	COG2198	Histidine kinase
PverR02_RS16240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PverR02_RS16255	COG1794	racemase activity, acting on amino acids and derivatives
PverR02_RS16260	COG1929	Belongs to the glycerate kinase type-1 family
PverR02_RS16265	COG3835	regulator
PverR02_RS16270	COG2271	Major facilitator Superfamily
PverR02_RS16280	COG0583	DNA-binding transcription factor activity
PverR02_RS16285	COG0667	Aldo Keto reductase
PverR02_RS16305	COG0697	spore germination
PverR02_RS16310	COG0583	DNA-binding transcription factor activity
PverR02_RS16315	COG2200	EAL domain
PverR02_RS16340	COG0667	Aldo Keto reductase
PverR02_RS16390	COG3258	Cytochrome c
PverR02_RS16395	COG2863	cytochrome
PverR02_RS16410	COG3145	DNA-N1-methyladenine dioxygenase activity
PverR02_RS16415	COG2169	Transcriptional regulator
PverR02_RS16415	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PverR02_RS16440	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
PverR02_RS16465	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
PverR02_RS16475	COG0640	Transcriptional regulator
PverR02_RS16485	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PverR02_RS16490	COG0431	NADPH-dependent FMN reductase
PverR02_RS16495	COG2207	Transcriptional regulator
PverR02_RS16495	COG1917	Cupin 2, conserved barrel domain protein
PverR02_RS16605	COG2207	Transcriptional regulator
PverR02_RS16605	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PverR02_RS16610	COG3938	Belongs to the proline racemase family
PverR02_RS16615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PverR02_RS16620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PverR02_RS16640	COG4770	biotin carboxylase activity
PverR02_RS16645	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PverR02_RS16650	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PverR02_RS16665	COG2186	Transcriptional regulator
PverR02_RS16670	COG4336	lyase activity
PverR02_RS16725	COG4381	Mu-like prophage protein gp46
PverR02_RS16760	COG4386	tail sheath protein
PverR02_RS16940	COG2366	antibiotic biosynthetic process
PverR02_RS16965	COG0840	transmembrane signaling receptor activity
PverR02_RS16975	COG2186	Transcriptional regulator
PverR02_RS16980	COG0579	oxidoreductase
PverR02_RS16985	COG0477	Major facilitator Superfamily
PverR02_RS17000	COG1238	metal cluster binding
PverR02_RS17010	COG0596	Alpha beta hydrolase
PverR02_RS17020	COG0297	glycogen (starch) synthase activity
PverR02_RS17025	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PverR02_RS17030	COG1640	4-alpha-glucanotransferase
PverR02_RS17105	COG0583	DNA-binding transcription factor activity
PverR02_RS17110	COG2814	Major facilitator Superfamily
PverR02_RS17115	COG0251	oxidation-reduction process
PverR02_RS17135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PverR02_RS17140	COG1802	Transcriptional regulator
PverR02_RS17155	COG0626	cystathionine gamma-synthase activity
PverR02_RS17160	COG1944	ATP diphosphatase activity
PverR02_RS17165	COG0840	transmembrane signaling receptor activity
PverR02_RS17170	COG2146	nitrite reductase [NAD(P)H] activity
PverR02_RS17170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PverR02_RS17175	COG2146	nitrite reductase [NAD(P)H] activity
PverR02_RS17175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PverR02_RS17180	COG0243	molybdopterin cofactor binding
PverR02_RS17190	COG0583	DNA-binding transcription factor activity
PverR02_RS17205	COG2271	Major facilitator Superfamily
PverR02_RS17230	COG3300	MHYT domain
PverR02_RS17230	COG5001	Diguanylate cyclase
PverR02_RS17235	COG2207	Transcriptional regulator
PverR02_RS17240	COG2223	nitrite transmembrane transporter activity
PverR02_RS17260	COG0154	amidase activity
PverR02_RS17275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PverR02_RS17280	COG0697	spore germination
PverR02_RS17330	COG2079	MmgE PrpD family protein
PverR02_RS17335	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS17340	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PverR02_RS17345	COG0583	DNA-binding transcription factor activity
PverR02_RS17350	COG3791	Glutathione-dependent formaldehyde-activating
PverR02_RS17355	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PverR02_RS17365	COG2205	protein histidine kinase activity
PverR02_RS17370	COG0745	RESPONSE REGULATOR receiver
PverR02_RS17380	COG0589	response to stress
PverR02_RS17400	COG0814	amino acid
PverR02_RS17410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PverR02_RS17420	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS17435	COG2818	Glycosylase
PverR02_RS17465	COG0714	Associated with various cellular activities
PverR02_RS17495	COG0420	3'-5' exonuclease activity
PverR02_RS17515	COG2706	6-phosphogluconolactonase activity
PverR02_RS17545	COG0318	PFAM AMP-dependent synthetase and ligase
PverR02_RS17550	COG0183	Belongs to the thiolase family
PverR02_RS17560	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS17565	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS17585	COG3239	Fatty acid desaturase
PverR02_RS17590	COG2267	carboxylic ester hydrolase activity
PverR02_RS17620	COG0656	L-ascorbic acid biosynthetic process
PverR02_RS17630	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PverR02_RS17665	COG0625	glutathione transferase activity
PverR02_RS17680	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PverR02_RS17690	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PverR02_RS17695	COG3842	ATPase activity
PverR02_RS17705	COG1175	transmembrane transport
PverR02_RS17715	COG1609	Transcriptional regulator
PverR02_RS17720	COG0019	diaminopimelate decarboxylase activity
PverR02_RS17730	COG2066	Belongs to the glutaminase family
PverR02_RS17740	COG2207	Transcriptional regulator
PverR02_RS17750	COG0673	inositol 2-dehydrogenase activity
PverR02_RS17825	COG4211	Belongs to the binding-protein-dependent transport system permease family
PverR02_RS17830	COG1129	ABC transporter
PverR02_RS17845	COG0673	inositol 2-dehydrogenase activity
PverR02_RS17850	COG0673	inositol 2-dehydrogenase activity
PverR02_RS17855	COG3962	Belongs to the TPP enzyme family
PverR02_RS17860	COG3718	enzyme involved in inositol metabolism
PverR02_RS17870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PverR02_RS17880	COG0745	RESPONSE REGULATOR receiver
PverR02_RS17905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PverR02_RS17915	COG0174	glutamine synthetase
PverR02_RS17930	COG0022	dehydrogenase e1 component
PverR02_RS17935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PverR02_RS17940	COG3284	Transcriptional regulator
PverR02_RS17955	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PverR02_RS17960	COG1522	sequence-specific DNA binding
PverR02_RS18090	COG0316	Belongs to the HesB IscA family
PverR02_RS18090	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
PverR02_RS18125	COG0789	Transcriptional regulator
PverR02_RS18135	COG0028	Belongs to the TPP enzyme family
PverR02_RS18140	COG0431	NADPH-dependent FMN reductase
PverR02_RS18165	COG0456	acetyltransferase
PverR02_RS18175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PverR02_RS18180	COG0328	RNA-DNA hybrid ribonuclease activity
PverR02_RS18190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PverR02_RS18195	COG0741	lytic transglycosylase activity
PverR02_RS18195	COG1388	LysM domain
PverR02_RS18200	COG4166	transmembrane transport
PverR02_RS18205	COG4166	transmembrane transport
PverR02_RS18210	COG4174	ABC transporter (Permease)
PverR02_RS18215	COG4239	(ABC) transporter, permease
PverR02_RS18220	COG4172	Belongs to the ABC transporter superfamily
PverR02_RS18225	COG3154	lipid carrier protein
PverR02_RS18230	COG0826	peptidase U32
PverR02_RS18235	COG0826	peptidase U32
PverR02_RS18240	COG0303	'Molybdopterin
PverR02_RS18245	COG0521	Mo-molybdopterin cofactor biosynthetic process
PverR02_RS18265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PverR02_RS18270	COG4166	transmembrane transport
PverR02_RS18275	COG4174	ABC transporter (Permease)
PverR02_RS18280	COG4239	(ABC) transporter, permease
PverR02_RS18285	COG4172	Belongs to the ABC transporter superfamily
PverR02_RS18295	COG2610	gluconate transmembrane transporter activity
PverR02_RS18300	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS18305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PverR02_RS18315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PverR02_RS18320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PverR02_RS18345	COG0765	amino acid transport
PverR02_RS18350	COG0765	amino acid transport
PverR02_RS18360	COG3118	belongs to the thioredoxin family
PverR02_RS18365	COG1253	flavin adenine dinucleotide binding
PverR02_RS18375	COG0698	ribose 5-phosphate isomerase
PverR02_RS18380	COG1129	ABC transporter
PverR02_RS18385	COG1172	Belongs to the binding-protein-dependent transport system permease family
PverR02_RS18390	COG1879	ABC-type sugar transport system periplasmic component
PverR02_RS18395	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS18400	COG1063	alcohol dehydrogenase
PverR02_RS18405	COG2376	Dihydroxyacetone kinase
PverR02_RS18415	COG0583	DNA-binding transcription factor activity
PverR02_RS18425	COG0616	signal peptide processing
PverR02_RS18445	COG5383	Protein conserved in bacteria
PverR02_RS18465	COG0587	DNA-directed DNA polymerase activity
PverR02_RS18480	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PverR02_RS18485	COG0494	nUDIX hydrolase
PverR02_RS18490	COG3706	GGDEF domain
PverR02_RS18500	COG1304	FMN binding
PverR02_RS18545	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PverR02_RS18545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PverR02_RS18560	COG2181	nitrate reductase activity
PverR02_RS18565	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
PverR02_RS18570	COG1140	nitrate reductase beta subunit
PverR02_RS18575	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PverR02_RS18580	COG2223	nitrite transmembrane transporter activity
PverR02_RS18590	COG3850	Histidine kinase
PverR02_RS18595	COG2197	response regulator
PverR02_RS18620	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
PverR02_RS18640	COG3901	Regulator of nitric oxide reductase transcription
PverR02_RS18640	COG0348	domain, Protein
PverR02_RS18645	COG3604	Transcriptional regulator
PverR02_RS18655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PverR02_RS18670	COG3256	nitric oxide reductase
PverR02_RS18675	COG2010	Cytochrome c
PverR02_RS18715	COG0714	Associated with various cellular activities
PverR02_RS18735	COG2010	Cytochrome c
PverR02_RS18740	COG3391	amine dehydrogenase activity
PverR02_RS18765	COG0535	radical SAM domain protein
PverR02_RS18770	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PverR02_RS18770	COG1648	precorrin-2 dehydrogenase activity
PverR02_RS18845	COG2207	Transcriptional regulator
PverR02_RS18855	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PverR02_RS18855	COG0475	glutathione-regulated potassium exporter activity
PverR02_RS18885	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PverR02_RS18915	COG0811	peptide transport
PverR02_RS19035	COG0583	DNA-binding transcription factor activity
PverR02_RS19045	COG1063	alcohol dehydrogenase
PverR02_RS19050	COG1902	pentaerythritol trinitrate reductase activity
PverR02_RS19060	COG1309	transcriptional regulator
PverR02_RS19075	COG1968	undecaprenyl-diphosphatase activity
PverR02_RS19080	COG0625	glutathione transferase activity
PverR02_RS19085	COG0583	DNA-binding transcription factor activity
PverR02_RS19110	COG0531	amino acid
PverR02_RS19125	COG0395	ABC-type sugar transport system, permease component
PverR02_RS19135	COG3842	ATPase activity
PverR02_RS19145	COG3284	Transcriptional regulator
PverR02_RS19180	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PverR02_RS19225	COG1247	-acetyltransferase
PverR02_RS19280	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PverR02_RS19285	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PverR02_RS19290	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PverR02_RS19295	COG2835	tetraacyldisaccharide 4'-kinase activity
PverR02_RS19300	COG1663	tetraacyldisaccharide 4'-kinase activity
PverR02_RS19305	COG0848	biopolymer transport protein
PverR02_RS19310	COG0811	peptide transport
PverR02_RS19315	COG2333	competence protein COMEC
PverR02_RS19315	COG0658	competence protein
PverR02_RS19335	COG0784	Response regulator, receiver
PverR02_RS19335	COG5002	protein histidine kinase activity
PverR02_RS19335	COG2205	protein histidine kinase activity
PverR02_RS19340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PverR02_RS19360	COG1393	Belongs to the ArsC family
PverR02_RS19380	COG0037	tRNA processing
PverR02_RS19390	COG3091	SprT-like family
PverR02_RS19395	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PverR02_RS19415	COG2920	part of a sulfur-relay system
PverR02_RS19420	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PverR02_RS19425	COG0435	Glutathione S-transferase
PverR02_RS19430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PverR02_RS19430	COG1648	precorrin-2 dehydrogenase activity
PverR02_RS19435	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PverR02_RS19440	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PverR02_RS19445	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PverR02_RS19450	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
PverR02_RS19455	COG1674	ftsk spoiiie
PverR02_RS19460	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PverR02_RS19465	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
PverR02_RS19470	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PverR02_RS19475	COG0542	response to heat
PverR02_RS19480	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PverR02_RS19485	COG1278	Cold shock
PverR02_RS19510	COG0482	sulfurtransferase activity
PverR02_RS19515	COG2915	High frequency lysogenization protein hflD homolog
PverR02_RS19525	COG2850	peptidyl-arginine hydroxylation
PverR02_RS19530	COG2153	protein acetylation
PverR02_RS19540	COG2224	Isocitrate lyase
PverR02_RS19545	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PverR02_RS19550	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PverR02_RS19555	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PverR02_RS19555	COG0649	NAD binding
PverR02_RS19570	COG1034	ATP synthesis coupled electron transport
PverR02_RS19575	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PverR02_RS19580	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PverR02_RS19590	COG0713	ATP synthesis coupled electron transport
PverR02_RS19605	COG1007	ATP synthesis coupled electron transport
PverR02_RS19635	COG2814	Major facilitator Superfamily
PverR02_RS19645	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS19665	COG0577	efflux transmembrane transporter activity
PverR02_RS19665	COG1136	(ABC) transporter
PverR02_RS19670	COG0577	efflux transmembrane transporter activity
PverR02_RS19670	COG1136	(ABC) transporter
PverR02_RS19750	COG2111	Na H antiporter
PverR02_RS19750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PverR02_RS19755	COG1006	Multisubunit Na H antiporter MnhC subunit
PverR02_RS19760	COG0651	ATP synthesis coupled electron transport
PverR02_RS19765	COG1863	multisubunit Na H antiporter MnhE subunit
PverR02_RS19770	COG2212	antiporter activity
PverR02_RS19775	COG1320	monovalent cation:proton antiporter activity
PverR02_RS19785	COG0215	cysteine-tRNA ligase activity
PverR02_RS19790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PverR02_RS19800	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PverR02_RS19805	COG2814	Major facilitator Superfamily
PverR02_RS19810	COG1566	PFAM secretion protein HlyD family protein
PverR02_RS19820	COG1846	Transcriptional regulator
PverR02_RS19825	COG2911	Protein conserved in bacteria
PverR02_RS19830	COG0729	surface antigen
PverR02_RS19840	COG0708	Exodeoxyribonuclease III
PverR02_RS19845	COG2885	chlorophyll binding
PverR02_RS19850	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS19860	COG0789	Transcriptional regulator
PverR02_RS19870	COG0318	PFAM AMP-dependent synthetase and ligase
PverR02_RS19875	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS19880	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PverR02_RS19905	COG2866	Carboxypeptidase
PverR02_RS19945	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
PverR02_RS19955	COG0217	transcriptional regulatory protein
PverR02_RS19960	COG0583	DNA-binding transcription factor activity
PverR02_RS19965	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PverR02_RS19970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PverR02_RS19975	COG3038	cytochrome b561
PverR02_RS19985	COG1902	pentaerythritol trinitrate reductase activity
PverR02_RS19985	COG0446	pyridine nucleotide-disulphide oxidoreductase
PverR02_RS20000	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PverR02_RS20005	COG1846	Transcriptional regulator
PverR02_RS20010	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PverR02_RS20020	COG0583	DNA-binding transcription factor activity
PverR02_RS20030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PverR02_RS20035	COG0776	regulation of translation
PverR02_RS20040	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PverR02_RS20045	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PverR02_RS20050	COG0740	serine-type endopeptidase activity
PverR02_RS20055	COG0544	peptidyl-prolyl cis-trans isomerase activity
PverR02_RS20080	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PverR02_RS20090	COG1686	Belongs to the peptidase S11 family
PverR02_RS20130	COG1477	protein flavinylation
PverR02_RS20175	COG1953	Uracil, thiamine, allantoin
PverR02_RS20185	COG0493	'glutamate synthase
PverR02_RS20195	COG1309	transcriptional regulator
PverR02_RS20205	COG1276	copper resistance
PverR02_RS20215	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PverR02_RS20225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
PverR02_RS20245	COG0471	metal ion transport
PverR02_RS20250	COG5002	protein histidine kinase activity
PverR02_RS20275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PverR02_RS20315	COG4585	Histidine kinase
PverR02_RS20330	COG1131	(ABC) transporter
PverR02_RS20350	COG0784	Response regulator, receiver
PverR02_RS20350	COG2205	protein histidine kinase activity
PverR02_RS20375	COG1522	sequence-specific DNA binding
PverR02_RS20380	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PverR02_RS20385	COG0022	dehydrogenase e1 component
PverR02_RS20395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PverR02_RS20400	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PverR02_RS20415	COG2423	ornithine cyclodeaminase activity
PverR02_RS20425	COG4215	(ABC) transporter
PverR02_RS20460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PverR02_RS20465	COG0577	efflux transmembrane transporter activity
PverR02_RS20465	COG1136	(ABC) transporter
PverR02_RS20480	COG2186	Transcriptional regulator
PverR02_RS20580	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PverR02_RS20610	COG0583	DNA-binding transcription factor activity
PverR02_RS20620	COG0625	glutathione transferase activity
PverR02_RS20625	COG0390	transport system, permease component
PverR02_RS20630	COG1122	ATPase activity
PverR02_RS20660	COG2423	ornithine cyclodeaminase activity
PverR02_RS20695	COG1450	Type ii and iii secretion system protein
PverR02_RS20715	COG3156	type II secretion system protein K
PverR02_RS20735	COG2165	general secretion pathway protein
PverR02_RS20740	COG1459	type II secretion system
PverR02_RS20745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PverR02_RS20750	COG4774	siderophore transport
PverR02_RS20765	COG1294	oxidase, subunit
PverR02_RS20800	COG0840	transmembrane signaling receptor activity
PverR02_RS20815	COG1053	succinate dehydrogenase
PverR02_RS20820	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS20825	COG1917	Cupin 2, conserved barrel domain protein
PverR02_RS20825	COG2169	Transcriptional regulator
PverR02_RS20875	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PverR02_RS20880	COG0573	inorganic phosphate transmembrane transporter activity
PverR02_RS20885	COG0581	inorganic phosphate transmembrane transporter activity
PverR02_RS20890	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PverR02_RS20905	COG0583	DNA-binding transcription factor activity
PverR02_RS20925	COG1902	pentaerythritol trinitrate reductase activity
PverR02_RS20935	COG0583	DNA-binding transcription factor activity
PverR02_RS20940	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PverR02_RS20940	COG2010	Cytochrome c
PverR02_RS20945	COG2080	2 iron, 2 sulfur cluster binding
PverR02_RS20950	COG2010	Cytochrome c
PverR02_RS20950	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PverR02_RS20960	COG3162	membrane
PverR02_RS20985	COG0583	DNA-binding transcription factor activity
PverR02_RS20990	COG2814	Major facilitator Superfamily
PverR02_RS21370	COG0270	DNA (cytosine-5-)-methyltransferase activity
PverR02_RS21420	COG0776	regulation of translation
PverR02_RS21425	COG0072	phenylalanine-tRNA ligase activity
PverR02_RS21430	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PverR02_RS21435	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PverR02_RS21440	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PverR02_RS21445	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PverR02_RS21450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PverR02_RS21460	COG1278	Cold shock
PverR02_RS21485	COG1869	D-ribose catabolic process
PverR02_RS21490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PverR02_RS21495	COG1609	Transcriptional regulator
PverR02_RS21500	COG1172	Belongs to the binding-protein-dependent transport system permease family
PverR02_RS21505	COG1129	ABC transporter
PverR02_RS21510	COG1879	ABC-type sugar transport system periplasmic component
PverR02_RS21535	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PverR02_RS21550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PverR02_RS21560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PverR02_RS21595	COG1286	toxin biosynthetic process
PverR02_RS21600	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PverR02_RS21605	COG0285	dihydrofolate synthase activity
PverR02_RS21610	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PverR02_RS21615	COG0135	phosphoribosylanthranilate isomerase activity
PverR02_RS21640	COG0473	3-isopropylmalate dehydrogenase activity
PverR02_RS21645	COG2226	methyltransferase
PverR02_RS21650	COG0066	3-isopropylmalate dehydratase activity
PverR02_RS21655	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PverR02_RS21685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PverR02_RS21695	COG0596	Alpha beta hydrolase
PverR02_RS21725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PverR02_RS21740	COG0556	nucleotide-excision repair
PverR02_RS21755	COG0583	DNA-binding transcription factor activity
PverR02_RS21760	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS21775	COG3591	Belongs to the peptidase S1B family
PverR02_RS21775	COG1864	DNA RNA non-specific endonuclease
PverR02_RS21780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PverR02_RS21785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PverR02_RS21790	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PverR02_RS21840	COG0840	transmembrane signaling receptor activity
PverR02_RS21845	COG2384	SAM-dependent methyltransferase
PverR02_RS21870	COG5285	phytanoyl-CoA dioxygenase
PverR02_RS21875	COG1126	abc transporter atp-binding protein
PverR02_RS21880	COG0583	DNA-binding transcription factor activity
PverR02_RS21890	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PverR02_RS21905	COG0840	transmembrane signaling receptor activity
PverR02_RS21915	COG2391	methyltransferase activity
PverR02_RS21925	COG1230	cation diffusion facilitator family transporter
PverR02_RS21945	COG3121	Chaperone
PverR02_RS21950	COG3539	Fimbrial protein
PverR02_RS21970	COG0473	3-isopropylmalate dehydrogenase activity
PverR02_RS21975	COG0281	malic enzyme
PverR02_RS21985	COG0659	secondary active sulfate transmembrane transporter activity
PverR02_RS21995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PverR02_RS22005	COG4221	oxidoreductase activity
PverR02_RS22025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PverR02_RS22035	COG0583	DNA-binding transcription factor activity
PverR02_RS22040	COG1304	FMN binding
PverR02_RS22055	COG5001	Diguanylate cyclase
PverR02_RS22055	COG5002	protein histidine kinase activity
PverR02_RS22070	COG1054	Belongs to the UPF0176 family
PverR02_RS22075	COG0271	Belongs to the BolA IbaG family
PverR02_RS22085	COG0114	fumarate hydratase activity
PverR02_RS22095	COG0697	spore germination
PverR02_RS22100	COG0183	Belongs to the thiolase family
PverR02_RS22105	COG2326	polyphosphate kinase activity
PverR02_RS22110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PverR02_RS22110	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PverR02_RS22115	COG0367	asparagine synthase
PverR02_RS22120	COG0189	ligase activity
PverR02_RS22120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PverR02_RS22125	COG1363	Peptidase, m42
PverR02_RS22130	COG3089	Belongs to the UPF0270 family
PverR02_RS22150	COG1368	sulfuric ester hydrolase activity
PverR02_RS22170	COG0318	PFAM AMP-dependent synthetase and ligase
PverR02_RS22180	COG2197	response regulator
PverR02_RS22185	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PverR02_RS22195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PverR02_RS22200	COG1073	alpha beta
PverR02_RS22225	COG2840	Smr protein MutS2
PverR02_RS22230	COG0302	gtp cyclohydrolase
PverR02_RS22255	COG2851	Citrate transporter
PverR02_RS22260	COG0583	DNA-binding transcription factor activity
PverR02_RS22265	COG0625	glutathione transferase activity
PverR02_RS22270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PverR02_RS22280	COG2252	PERMEase
PverR02_RS22330	COG4266	Belongs to the allantoicase family
PverR02_RS22335	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
PverR02_RS22355	COG1560	Kdo2-lipid A biosynthetic process
PverR02_RS22360	COG0850	regulation of cytokinetic process
PverR02_RS22365	COG2894	cell division
PverR02_RS22370	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
PverR02_RS22375	COG0564	pseudouridine synthase activity
PverR02_RS22380	COG1362	aminopeptidase activity
PverR02_RS22385	COG0668	transmembrane transport
PverR02_RS22400	COG3023	N-Acetylmuramoyl-L-alanine amidase
PverR02_RS22405	COG0642	Histidine kinase
PverR02_RS22420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PverR02_RS22460	COG1309	transcriptional regulator
PverR02_RS22470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PverR02_RS22480	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS22500	COG3123	guanosine phosphorylase activity
PverR02_RS22505	COG3217	Mosc domain protein beta barrel domain protein
PverR02_RS22505	COG0633	Ferredoxin
PverR02_RS22520	COG3851	Histidine kinase
PverR02_RS22525	COG2197	response regulator
PverR02_RS22530	COG1597	lipid kinase activity
PverR02_RS22540	COG0835	chemotaxis
PverR02_RS22550	COG1192	Involved in chromosome partitioning
PverR02_RS22555	COG1360	Flagellar Motor Protein
PverR02_RS22560	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
PverR02_RS22565	COG2201	protein-glutamate methylesterase activity
PverR02_RS22570	COG0784	Response regulator, receiver
PverR02_RS22570	COG2198	Histidine kinase
PverR02_RS22570	COG0643	Histidine kinase
PverR02_RS22575	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
PverR02_RS22605	COG1278	Cold shock
PverR02_RS22625	COG1278	Cold shock
PverR02_RS22635	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PverR02_RS22720	COG1677	Flagellar hook-basal body complex protein FliE
PverR02_RS22750	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PverR02_RS22760	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PverR02_RS22765	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PverR02_RS22775	COG4786	Flagellar basal body rod
PverR02_RS22775	COG1256	bacterial-type flagellum assembly
PverR02_RS22785	COG1706	bacterial-type flagellum-dependent cell motility
PverR02_RS22790	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
PverR02_RS22800	COG4787	bacterial-type flagellum-dependent cell motility
PverR02_RS22820	COG2154	pterin-4-alpha-carbinolamine dehydratase
PverR02_RS22835	COG2207	Transcriptional regulator
PverR02_RS22855	COG1752	Esterase of the alpha-beta hydrolase superfamily
PverR02_RS22860	COG1846	Transcriptional regulator
PverR02_RS22865	COG0514	ATP-dependent DNA helicase (RecQ)
PverR02_RS22875	COG2832	Protein of unknown function (DUF454)
PverR02_RS22880	COG2205	protein histidine kinase activity
PverR02_RS22880	COG0784	Response regulator, receiver
PverR02_RS22930	COG1846	Transcriptional regulator
PverR02_RS22935	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PverR02_RS22940	COG0406	alpha-ribazole phosphatase activity
PverR02_RS22945	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PverR02_RS22955	COG1492	cobalamin metabolic process
PverR02_RS22965	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PverR02_RS22970	COG0778	Nitroreductase
PverR02_RS22975	COG1797	cobyrinic acid a,c-diamide synthase activity
PverR02_RS22990	COG0791	NLP P60 protein
PverR02_RS22995	COG0791	NLP P60 protein
PverR02_RS23000	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PverR02_RS23005	COG0628	permease
PverR02_RS23015	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PverR02_RS23020	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PverR02_RS23035	COG3122	Protein conserved in bacteria
PverR02_RS23040	COG3956	TIGRFAM MazG family protein
PverR02_RS23045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PverR02_RS23050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PverR02_RS23055	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PverR02_RS23060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PverR02_RS23100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PverR02_RS23105	COG0583	DNA-binding transcription factor activity
PverR02_RS23115	COG1953	Uracil, thiamine, allantoin
PverR02_RS23120	COG2996	Protein conserved in bacteria
PverR02_RS23145	COG0513	Belongs to the DEAD box helicase family
PverR02_RS23150	COG0668	transmembrane transport
PverR02_RS23190	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PverR02_RS23215	COG1132	(ABC) transporter
PverR02_RS23220	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PverR02_RS23230	COG2188	Transcriptional regulator
PverR02_RS23240	COG1595	DNA-templated transcription, initiation
PverR02_RS23250	COG1643	Atp-dependent helicase
PverR02_RS23255	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
PverR02_RS23275	COG0840	transmembrane signaling receptor activity
PverR02_RS23285	COG3278	Belongs to the heme-copper respiratory oxidase family
PverR02_RS23300	COG2010	Cytochrome c
PverR02_RS23305	COG3278	Belongs to the heme-copper respiratory oxidase family
PverR02_RS23320	COG2010	Cytochrome c
PverR02_RS23325	COG0348	domain, Protein
PverR02_RS23360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PverR02_RS23365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PverR02_RS23370	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PverR02_RS23375	COG2130	NADP-dependent
PverR02_RS23380	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PverR02_RS23385	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PverR02_RS23405	COG0583	DNA-binding transcription factor activity
PverR02_RS23430	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PverR02_RS23435	COG3115	cell septum assembly
PverR02_RS23455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PverR02_RS23465	COG0402	S-adenosylhomocysteine deaminase activity
PverR02_RS23470	COG1802	Transcriptional regulator
PverR02_RS23475	COG3135	benzoate transporter
PverR02_RS23480	COG3171	Protein conserved in bacteria
PverR02_RS23495	COG0116	Belongs to the methyltransferase superfamily
PverR02_RS23495	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PverR02_RS23500	COG3130	regulation of translation
PverR02_RS23505	COG0167	dihydroorotate dehydrogenase activity
PverR02_RS23520	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PverR02_RS23530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PverR02_RS23535	COG3707	response regulator
PverR02_RS23540	COG2223	nitrite transmembrane transporter activity
PverR02_RS23550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PverR02_RS23555	COG2885	chlorophyll binding
PverR02_RS23555	COG3047	cAMP biosynthetic process
PverR02_RS23580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PverR02_RS23595	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
PverR02_RS23600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PverR02_RS23615	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PverR02_RS23620	COG1045	serine acetyltransferase
PverR02_RS23625	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PverR02_RS23635	COG2079	MmgE PrpD family protein
PverR02_RS23655	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PverR02_RS23660	COG0372	Belongs to the citrate synthase family
PverR02_RS23670	COG1802	Transcriptional regulator
PverR02_RS23675	COG4067	protein conserved in archaea
PverR02_RS23675	COG0189	ligase activity
PverR02_RS23685	COG0189	ligase activity
PverR02_RS23705	COG0560	Phosphoserine phosphatase
PverR02_RS23715	COG1953	Uracil, thiamine, allantoin
PverR02_RS23725	COG0583	DNA-binding transcription factor activity
PverR02_RS23730	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS23735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PverR02_RS23745	COG0583	DNA-binding transcription factor activity
PverR02_RS23785	COG1024	Enoyl-CoA hydratase
PverR02_RS23785	COG1250	3-hydroxyacyl-CoA dehydrogenase
PverR02_RS23795	COG0598	Magnesium transport protein CorA
PverR02_RS23800	COG0519	Catalyzes the synthesis of GMP from XMP
PverR02_RS23800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PverR02_RS23805	COG1024	Enoyl-CoA hydratase
PverR02_RS23805	COG1250	3-hydroxyacyl-CoA dehydrogenase
PverR02_RS23810	COG0183	Belongs to the thiolase family
PverR02_RS23820	COG1305	Transglutaminase-like
PverR02_RS23830	COG2308	Evidence 4 Homologs of previously reported genes of
PverR02_RS23860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PverR02_RS23865	COG2885	chlorophyll binding
PverR02_RS23865	COG3047	cAMP biosynthetic process
PverR02_RS23895	COG2207	Transcriptional regulator
PverR02_RS23900	COG1064	alcohol dehydrogenase
PverR02_RS23905	COG1414	Transcriptional regulator
PverR02_RS23910	COG1172	Belongs to the binding-protein-dependent transport system permease family
PverR02_RS23915	COG1129	ABC transporter
PverR02_RS23920	COG1879	ABC-type sugar transport system periplasmic component
PverR02_RS23925	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS23940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PverR02_RS23950	COG1397	ADP-ribosylglycohydrolase
PverR02_RS23955	COG2188	Transcriptional regulator
PverR02_RS23970	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PverR02_RS23980	COG0084	hydrolase, TatD family'
PverR02_RS23990	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PverR02_RS23995	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PverR02_RS24005	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PverR02_RS24010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PverR02_RS24025	COG0416	fatty acid biosynthetic process
PverR02_RS24030	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PverR02_RS24035	COG1399	metal-binding, possibly nucleic acid-binding protein
PverR02_RS24040	COG0424	maF-like protein
PverR02_RS24045	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PverR02_RS24045	COG0616	signal peptide processing
PverR02_RS24050	COG0546	phosphoglycolate phosphatase activity
PverR02_RS24065	COG1530	ribonuclease E activity
PverR02_RS24075	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PverR02_RS24075	COG3608	succinylglutamate desuccinylase aspartoacylase
PverR02_RS24090	COG1301	dicarboxylic acid transport
PverR02_RS24095	COG4977	sequence-specific DNA binding
PverR02_RS24095	COG1917	Cupin 2, conserved barrel domain protein
PverR02_RS24115	COG2977	Belongs to the P-Pant transferase superfamily
PverR02_RS24120	COG2205	protein histidine kinase activity
PverR02_RS24125	COG0745	RESPONSE REGULATOR receiver
PverR02_RS24165	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
PverR02_RS24170	COG0784	Response regulator, receiver
PverR02_RS24170	COG0835	chemotaxis
PverR02_RS24190	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
PverR02_RS24195	COG0477	Major facilitator Superfamily
PverR02_RS24200	COG4993	Dehydrogenase
PverR02_RS24210	COG0640	Transcriptional regulator
PverR02_RS24280	COG2239	Acts as a magnesium transporter
PverR02_RS24300	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PverR02_RS24305	COG0527	aspartate kinase activity
PverR02_RS24310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PverR02_RS24315	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
PverR02_RS24320	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PverR02_RS24325	COG2988	succinylglutamate desuccinylase activity
PverR02_RS24335	COG3724	N-succinylarginine dihydrolase activity
PverR02_RS24340	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS24355	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PverR02_RS24400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PverR02_RS24420	COG0583	DNA-binding transcription factor activity
PverR02_RS24465	COG3706	GGDEF domain
PverR02_RS24480	COG0504	CTP synthase activity
PverR02_RS24485	COG2329	Antibiotic biosynthesis monooxygenase
PverR02_RS24495	COG0584	glycerophosphoryl diester phosphodiesterase
PverR02_RS24515	COG0306	phosphate transporter
PverR02_RS24520	COG1984	allophanate hydrolase subunit 2
PverR02_RS24530	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PverR02_RS24540	COG0583	DNA-binding transcription factor activity
PverR02_RS24545	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS24555	COG0583	DNA-binding transcription factor activity
PverR02_RS24560	COG4941	Belongs to the sigma-70 factor family
PverR02_RS24565	COG3795	YCII-related domain
PverR02_RS24585	COG0436	Aminotransferase
PverR02_RS24600	COG3265	gluconokinase activity
PverR02_RS24605	COG1609	Transcriptional regulator
PverR02_RS24630	COG0242	peptide deformylase activity
PverR02_RS24635	COG1295	ribonuclease BN
PverR02_RS24640	COG3237	CsbD-like
PverR02_RS24650	COG0318	PFAM AMP-dependent synthetase and ligase
PverR02_RS24655	COG0318	PFAM AMP-dependent synthetase and ligase
PverR02_RS24660	COG0596	Alpha beta hydrolase
PverR02_RS24665	COG2030	dehydratase
PverR02_RS24675	COG3530	Putative quorum-sensing-regulated virulence factor
PverR02_RS24680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PverR02_RS24685	COG0800	Aldolase
PverR02_RS24700	COG1737	Transcriptional regulator
PverR02_RS24705	COG0676	glucose-6-phosphate 1-epimerase activity
PverR02_RS24715	COG3842	ATPase activity
PverR02_RS24720	COG0395	ABC-type sugar transport system, permease component
PverR02_RS24725	COG1175	transmembrane transport
PverR02_RS24730	COG1653	transport
PverR02_RS24745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PverR02_RS24750	COG0583	DNA-binding transcription factor activity
PverR02_RS24760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PverR02_RS24785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PverR02_RS24815	COG1113	amino acid transport
PverR02_RS24835	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PverR02_RS24845	COG0009	L-threonylcarbamoyladenylate synthase
PverR02_RS24855	COG2917	probably involved in intracellular septation
PverR02_RS24860	COG2350	Protein conserved in bacteria
PverR02_RS24870	COG0745	RESPONSE REGULATOR receiver
PverR02_RS24880	COG0642	Histidine kinase
PverR02_RS24885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PverR02_RS24925	COG0509	glycine decarboxylation via glycine cleavage system
PverR02_RS24930	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PverR02_RS24930	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PverR02_RS24935	COG1760	l-serine dehydratase
PverR02_RS24940	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PverR02_RS24945	COG1278	Cold shock
PverR02_RS24955	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PverR02_RS24975	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PverR02_RS24980	COG0602	queuosine metabolic process
PverR02_RS24985	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
PverR02_RS24990	COG2885	chlorophyll binding
PverR02_RS24995	COG0823	Involved in the tonB-independent uptake of proteins
PverR02_RS25015	COG0824	Thioesterase
PverR02_RS25020	COG2255	four-way junction helicase activity
PverR02_RS25025	COG0632	four-way junction helicase activity
PverR02_RS25030	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PverR02_RS25035	COG0217	transcriptional regulatory protein
PverR02_RS25040	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PverR02_RS25055	COG0783	Belongs to the Dps family
PverR02_RS25065	COG2900	Belongs to the SlyX family
PverR02_RS25080	COG0668	transmembrane transport
PverR02_RS25085	COG1666	GTP binding
PverR02_RS25095	COG4191	Histidine kinase
PverR02_RS25095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PverR02_RS25100	COG2096	Adenosyltransferase
PverR02_RS25110	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PverR02_RS25115	COG0653	protein targeting
PverR02_RS25125	COG0433	COG0433 Predicted ATPase
PverR02_RS25135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PverR02_RS25135	COG0438	transferase activity, transferring glycosyl groups
PverR02_RS25150	COG0788	formyltetrahydrofolate deformylase activity
PverR02_RS25160	COG2925	Exonuclease
PverR02_RS25195	COG0714	Associated with various cellular activities
PverR02_RS25215	COG0469	pyruvate kinase activity
PverR02_RS25220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PverR02_RS25230	COG4191	Histidine kinase
PverR02_RS25240	COG0477	Major facilitator Superfamily
PverR02_RS25260	COG2207	Transcriptional regulator
PverR02_RS25290	COG1595	DNA-templated transcription, initiation
PverR02_RS25295	COG3712	iron ion homeostasis
PverR02_RS25310	COG2832	Protein of unknown function (DUF454)
PverR02_RS25315	COG0840	transmembrane signaling receptor activity
PverR02_RS25345	COG3642	lipopolysaccharide core region biosynthetic process
PverR02_RS25365	COG1368	sulfuric ester hydrolase activity
PverR02_RS25375	COG0459	protein refolding
PverR02_RS25380	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PverR02_RS25405	COG2211	Major facilitator Superfamily
PverR02_RS25410	COG0442	prolyl-tRNA aminoacylation
PverR02_RS25420	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PverR02_RS25430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PverR02_RS25435	COG0842	Transport permease protein
PverR02_RS25435	COG1129	ABC transporter
PverR02_RS25440	COG0842	Transport permease protein
PverR02_RS25470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PverR02_RS25505	COG4974	Belongs to the 'phage' integrase family
PverR02_RS25510	COG0335	large ribosomal subunit rRNA binding
PverR02_RS25515	COG0336	Belongs to the RNA methyltransferase TrmD family
PverR02_RS25520	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PverR02_RS25525	COG0228	four-way junction DNA binding
PverR02_RS25530	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PverR02_RS25540	COG4536	flavin adenine dinucleotide binding
PverR02_RS25545	COG0477	Major facilitator Superfamily
PverR02_RS25550	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PverR02_RS25585	COG2188	Transcriptional regulator
PverR02_RS25590	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PverR02_RS25595	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PverR02_RS25600	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PverR02_RS25600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PverR02_RS25605	COG1263	PTS System
PverR02_RS25605	COG2190	(PTS) system
PverR02_RS25605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PverR02_RS25615	COG0047	phosphoribosylformylglycinamidine synthase activity
PverR02_RS25615	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PverR02_RS25620	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PverR02_RS25640	COG0366	Alpha amylase catalytic
PverR02_RS25645	COG1263	PTS System
PverR02_RS25645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PverR02_RS25650	COG2188	Transcriptional regulator
PverR02_RS25655	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PverR02_RS25655	COG0519	Catalyzes the synthesis of GMP from XMP
PverR02_RS25680	COG0583	DNA-binding transcription factor activity
PverR02_RS25685	COG1570	exodeoxyribonuclease VII activity
PverR02_RS25690	COG0739	heme binding
PverR02_RS25700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PverR02_RS25710	COG0436	Aminotransferase
PverR02_RS25715	COG1160	GTP binding
PverR02_RS25730	COG0124	histidyl-tRNA synthetase
PverR02_RS25735	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PverR02_RS25740	COG1426	Protein conserved in bacteria
PverR02_RS25740	COG1426	Protein conserved in bacteria
PverR02_RS25750	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PverR02_RS25755	COG0105	UTP biosynthetic process
PverR02_RS25765	COG0633	Ferredoxin
PverR02_RS25770	COG0443	Heat shock 70 kDa protein
PverR02_RS25775	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PverR02_RS25780	COG0316	Belongs to the HesB IscA family
PverR02_RS25790	COG1104	cysteine desulfurase activity
PverR02_RS25800	COG1045	serine acetyltransferase
PverR02_RS25815	COG3134	Outer membrane lipoprotein
PverR02_RS25830	COG1862	Preprotein translocase
PverR02_RS25835	COG0343	queuine tRNA-ribosyltransferase activity
PverR02_RS25840	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PverR02_RS25935	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PverR02_RS25955	COG0583	DNA-binding transcription factor activity
PverR02_RS25980	COG1815	bacterial-type flagellum-dependent cell motility
PverR02_RS25985	COG1558	bacterial-type flagellum-dependent cell motility
PverR02_RS26015	COG1706	bacterial-type flagellum-dependent cell motility
PverR02_RS26020	COG1705	Flagellar rod assembly protein muramidase FlgJ
PverR02_RS26020	COG3951	Flagellar rod assembly protein muramidase FlgJ
PverR02_RS26030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PverR02_RS26045	COG1987	bacterial-type flagellum assembly
PverR02_RS26060	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PverR02_RS26100	COG1766	The M ring may be actively involved in energy transduction
PverR02_RS26105	COG1677	Flagellar hook-basal body complex protein FliE
PverR02_RS26110	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PverR02_RS26140	COG1360	Flagellar Motor Protein
PverR02_RS26165	COG1191	sigma factor activity
PverR02_RS26195	COG1280	lysine exporter protein (LysE YggA)
PverR02_RS26225	COG0745	RESPONSE REGULATOR receiver
PverR02_RS26240	COG3706	GGDEF domain
PverR02_RS26255	COG2161	toxin-antitoxin pair type II binding
PverR02_RS26260	COG4115	mRNA cleavage
PverR02_RS26270	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PverR02_RS26275	COG0109	protoheme IX farnesyltransferase activity
PverR02_RS26285	COG1845	cytochrome c oxidase, subunit III
PverR02_RS26290	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PverR02_RS26295	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PverR02_RS26305	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PverR02_RS26310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PverR02_RS26310	COG1017	nitric oxide dioxygenase activity
PverR02_RS26315	COG3604	Transcriptional regulator
PverR02_RS26325	COG3708	Transcriptional regulator
PverR02_RS26325	COG2207	Transcriptional regulator
PverR02_RS26330	COG2197	response regulator
PverR02_RS26345	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS26360	COG1346	cytolysis
PverR02_RS26365	COG1380	Effector of murein hydrolase LrgA
PverR02_RS26370	COG0583	DNA-binding transcription factor activity
PverR02_RS26380	COG1366	Belongs to the anti-sigma-factor antagonist family
PverR02_RS26405	COG0302	gtp cyclohydrolase
PverR02_RS26410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PverR02_RS26425	COG0492	ferredoxin-NADP+ reductase activity
PverR02_RS26430	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
PverR02_RS26455	COG0386	Belongs to the glutathione peroxidase family
PverR02_RS26460	COG3045	CreA protein
PverR02_RS26465	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PverR02_RS26470	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PverR02_RS26475	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PverR02_RS26480	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PverR02_RS26485	COG0142	geranyltranstransferase activity
PverR02_RS26490	COG2824	Alkylphosphonate utilization operon protein PhnA
PverR02_RS26495	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PverR02_RS26500	COG0545	Peptidyl-prolyl cis-trans isomerase
PverR02_RS26505	COG0840	transmembrane signaling receptor activity
PverR02_RS26515	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
PverR02_RS26525	COG2610	gluconate transmembrane transporter activity
PverR02_RS26535	COG0659	secondary active sulfate transmembrane transporter activity
PverR02_RS26545	COG0583	DNA-binding transcription factor activity
PverR02_RS26550	COG2249	NAD(P)H dehydrogenase (quinone) activity
PverR02_RS26560	COG0583	DNA-binding transcription factor activity
PverR02_RS26565	COG1113	amino acid transport
PverR02_RS26575	COG1522	sequence-specific DNA binding
PverR02_RS26580	COG3485	protocatechuate 3,4-dioxygenase
PverR02_RS26585	COG4829	muconolactone delta-isomerase
PverR02_RS26590	COG4948	Mandelate Racemase Muconate Lactonizing
PverR02_RS26605	COG4638	Rieske (2fe-2S)
PverR02_RS26610	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PverR02_RS26615	COG0543	2 iron, 2 sulfur cluster binding
PverR02_RS26615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PverR02_RS26620	COG1113	amino acid transport
PverR02_RS26625	COG3483	tryptophan 2,3-dioxygenase activity
PverR02_RS26630	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
PverR02_RS26675	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PverR02_RS26680	COG1074	ATP-dependent DNA helicase activity
PverR02_RS26685	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PverR02_RS26720	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
PverR02_RS26725	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PverR02_RS26730	COG1183	phosphatidylcholine synthase activity
PverR02_RS26735	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PverR02_RS26745	COG0028	Belongs to the TPP enzyme family
PverR02_RS26750	COG3098	single-species biofilm formation
PverR02_RS26760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PverR02_RS26780	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PverR02_RS26785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PverR02_RS26790	COG4558	Periplasmic binding protein
PverR02_RS26800	COG1489	DNA binding
PverR02_RS26805	COG0436	Aminotransferase
PverR02_RS26815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PverR02_RS26820	COG3852	Histidine kinase
PverR02_RS26840	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PverR02_RS26845	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PverR02_RS26850	COG0166	Belongs to the GPI family
PverR02_RS26855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PverR02_RS26865	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PverR02_RS26875	COG2823	Periplasmic or secreted lipoprotein
PverR02_RS26880	COG1185	polyribonucleotide nucleotidyltransferase activity
PverR02_RS26885	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PverR02_RS26890	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PverR02_RS26895	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PverR02_RS26900	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PverR02_RS26905	COG0195	Participates in both transcription termination and antitermination
PverR02_RS26910	COG0779	Required for maturation of 30S ribosomal subunits
PverR02_RS26925	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PverR02_RS26930	COG0149	triose-phosphate isomerase activity
PverR02_RS26935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PverR02_RS26940	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PverR02_RS26950	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
PverR02_RS26965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PverR02_RS26970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PverR02_RS26975	COG0505	Belongs to the CarA family
PverR02_RS26980	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PverR02_RS26985	COG0484	heat shock protein binding
PverR02_RS26990	COG0443	Heat shock 70 kDa protein
PverR02_RS26995	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PverR02_RS27000	COG0497	DNA recombination
PverR02_RS27010	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PverR02_RS27015	COG2914	Belongs to the UPF0125 (RnfH) family
PverR02_RS27025	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PverR02_RS27030	COG2186	Transcriptional regulator
PverR02_RS27035	COG1620	l-lactate permease
PverR02_RS27040	COG0247	lactate metabolic process
PverR02_RS27070	COG0582	viral genome integration into host DNA
PverR02_RS27090	COG4983	Phage plasmid primase, P4 family domain protein
PverR02_RS27175	COG0583	DNA-binding transcription factor activity
PverR02_RS27180	COG2271	Major facilitator Superfamily
PverR02_RS27185	COG1473	amidohydrolase
PverR02_RS27195	COG1309	transcriptional regulator
PverR02_RS27205	COG2814	Major facilitator Superfamily
PverR02_RS27225	COG0583	DNA-binding transcription factor activity
PverR02_RS27230	COG0129	dihydroxy-acid dehydratase activity
PverR02_RS27250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PverR02_RS27265	COG0583	DNA-binding transcription factor activity
PverR02_RS27275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PverR02_RS27290	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PverR02_RS27295	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS27330	COG1802	Transcriptional regulator
PverR02_RS27335	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PverR02_RS27340	COG1028	Short-chain dehydrogenase reductase Sdr
PverR02_RS27345	COG2207	Transcriptional regulator
PverR02_RS27350	COG0477	Major facilitator Superfamily
PverR02_RS27395	COG0784	Response regulator, receiver
PverR02_RS27395	COG0835	chemotaxis
PverR02_RS27405	COG0840	transmembrane signaling receptor activity
PverR02_RS27415	COG2862	Uncharacterized protein family, UPF0114
PverR02_RS27430	COG1067	ATP-dependent peptidase activity
PverR02_RS27455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PverR02_RS27465	COG0488	(ABC) transporter
PverR02_RS27475	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PverR02_RS27485	COG0523	cobalamin synthesis protein
PverR02_RS27490	COG2879	small protein
PverR02_RS27495	COG1966	Carbon starvation protein
PverR02_RS27520	COG1970	mechanosensitive ion channel activity
PverR02_RS27530	COG2197	response regulator
PverR02_RS27535	COG2813	Specifically methylates the guanine in position
PverR02_RS27545	COG1294	oxidase, subunit
PverR02_RS27550	COG1271	oxidase subunit
PverR02_RS27565	COG2252	PERMEase
PverR02_RS27570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PverR02_RS27585	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PverR02_RS27590	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PverR02_RS27595	COG1309	transcriptional regulator
PverR02_RS27600	COG1082	Xylose isomerase domain protein TIM barrel
PverR02_RS27600	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PverR02_RS27605	COG0477	Major facilitator Superfamily
PverR02_RS27620	COG2321	neutral zinc metallopeptidase
PverR02_RS27635	COG1946	Acyl-CoA thioesterase
PverR02_RS27645	COG0123	including yeast histone deacetylase and acetoin utilization protein
PverR02_RS27650	COG2081	HI0933 family
PverR02_RS27655	COG0513	Belongs to the DEAD box helicase family
PverR02_RS27660	COG0697	spore germination
PverR02_RS27665	COG1522	sequence-specific DNA binding
PverR02_RS27685	COG1199	ATP-dependent helicase activity
PverR02_RS27685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PverR02_RS27695	COG3416	Protein conserved in bacteria
PverR02_RS27710	COG1643	Atp-dependent helicase
PverR02_RS27720	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PverR02_RS27730	COG1522	sequence-specific DNA binding
PverR02_RS27745	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PverR02_RS27750	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS27755	COG0784	Response regulator, receiver
PverR02_RS27755	COG2198	Histidine kinase
PverR02_RS27755	COG2205	protein histidine kinase activity
PverR02_RS27760	COG0351	phosphomethylpyrimidine kinase
PverR02_RS27765	COG0352	thiamine-phosphate diphosphorylase activity
PverR02_RS27770	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PverR02_RS27785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PverR02_RS27790	COG1702	phosphate starvation-inducible protein PhoH
PverR02_RS27795	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PverR02_RS27800	COG4535	Mg2 and Co2 transporter CorC
PverR02_RS27805	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PverR02_RS27820	COG0495	leucyl-tRNA aminoacylation
PverR02_RS27840	COG2951	lytic endotransglycosylase activity
PverR02_RS27845	COG1619	proteins homologs of microcin C7 resistance protein MccF
PverR02_RS27850	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PverR02_RS27855	COG0321	lipoyl(octanoyl) transferase activity
PverR02_RS27860	COG2921	Belongs to the UPF0250 family
PverR02_RS27865	COG1686	Belongs to the peptidase S11 family
PverR02_RS27875	COG2951	lytic endotransglycosylase activity
PverR02_RS27880	COG0772	Belongs to the SEDS family
PverR02_RS27885	COG0768	penicillin binding
PverR02_RS27890	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PverR02_RS27900	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PverR02_RS27905	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PverR02_RS27910	COG2094	Belongs to the DNA glycosylase MPG family
PverR02_RS27915	COG0586	Pfam SNARE associated Golgi protein
PverR02_RS27930	COG1346	cytolysis
PverR02_RS27950	COG0702	epimerase
PverR02_RS27965	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PverR02_RS27975	COG3284	Transcriptional regulator
PverR02_RS27985	COG0531	amino acid
PverR02_RS27990	COG4303	Ethanolamine ammonia lyase large subunit
PverR02_RS27995	COG4302	ethanolamine ammonia-lyase activity
PverR02_RS28000	COG0456	acetyltransferase
PverR02_RS28005	COG0586	Pfam SNARE associated Golgi protein
PverR02_RS28010	COG3228	Belongs to the MtfA family
PverR02_RS28015	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PverR02_RS28045	COG4774	siderophore transport
PverR02_RS28055	COG1595	DNA-templated transcription, initiation
PverR02_RS28065	COG0842	Transport permease protein
PverR02_RS28070	COG0842	Transport permease protein
PverR02_RS28070	COG1129	ABC transporter
PverR02_RS28075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PverR02_RS28080	COG1538	Outer membrane efflux protein
PverR02_RS28090	COG5002	protein histidine kinase activity
PverR02_RS28095	COG0745	RESPONSE REGULATOR receiver
PverR02_RS28100	COG0156	8-amino-7-oxononanoate synthase activity
PverR02_RS28115	COG1335	isochorismatase
PverR02_RS28125	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PverR02_RS28135	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PverR02_RS28150	COG2249	NAD(P)H dehydrogenase (quinone) activity
PverR02_RS28170	COG1722	exodeoxyribonuclease VII activity
PverR02_RS28175	COG0142	geranyltranstransferase activity
PverR02_RS28180	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PverR02_RS28185	COG4206	TonB-dependent receptor
PverR02_RS28190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PverR02_RS28200	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PverR02_RS28205	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PverR02_RS28210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PverR02_RS28215	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PverR02_RS28230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PverR02_RS28230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PverR02_RS28245	COG2264	protein methyltransferase activity
PverR02_RS28250	COG3118	belongs to the thioredoxin family
PverR02_RS28265	COG4181	ATPase activity
PverR02_RS28290	COG1201	RNA secondary structure unwinding
PverR02_RS28300	COG1335	isochorismatase
PverR02_RS28305	COG4106	trans-aconitate 2-methyltransferase activity
PverR02_RS28310	COG0629	single-stranded DNA binding
PverR02_RS28315	COG2814	Major facilitator Superfamily
PverR02_RS28320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PverR02_RS28325	COG2193	ferroxidase activity
PverR02_RS28335	COG0203	ribosomal protein L17
PverR02_RS28340	COG0202	RNA polymerase activity
PverR02_RS28345	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PverR02_RS28350	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PverR02_RS28355	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PverR02_RS28360	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PverR02_RS28370	COG0200	Binds to the 23S rRNA
PverR02_RS28375	COG1841	ribosomal large subunit assembly
PverR02_RS28380	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PverR02_RS28385	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PverR02_RS28390	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PverR02_RS28395	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PverR02_RS28400	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PverR02_RS28405	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PverR02_RS28410	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PverR02_RS28415	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PverR02_RS28420	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PverR02_RS28425	COG0255	Belongs to the universal ribosomal protein uL29 family
PverR02_RS28430	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PverR02_RS28435	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PverR02_RS28440	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PverR02_RS28445	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PverR02_RS28450	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PverR02_RS28455	COG0089	rRNA binding
PverR02_RS28460	COG0088	Forms part of the polypeptide exit tunnel
PverR02_RS28465	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PverR02_RS28470	COG0051	transcription antitermination factor activity, RNA binding
PverR02_RS28475	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PverR02_RS28480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PverR02_RS28485	COG0049	tRNA binding
PverR02_RS28490	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PverR02_RS28495	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PverR02_RS28500	COG0085	RNA polymerase activity
PverR02_RS28505	COG0222	ribosome binding
PverR02_RS28510	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PverR02_RS28515	COG0081	regulation of translation
PverR02_RS28520	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PverR02_RS28560	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PverR02_RS28600	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PverR02_RS28605	COG0739	heme binding
PverR02_RS28610	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PverR02_RS28615	COG0316	Belongs to the HesB IscA family
PverR02_RS28620	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PverR02_RS28625	COG1981	membrane
PverR02_RS28640	COG4221	oxidoreductase activity
PverR02_RS28645	COG0537	adenosine 5'-monophosphoramidase activity
PverR02_RS28650	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
PverR02_RS28655	COG1765	OsmC-like protein
PverR02_RS28670	COG0134	indole-3-glycerol-phosphate synthase activity
PverR02_RS28675	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PverR02_RS28680	COG0512	Glutamine amidotransferase of anthranilate synthase
PverR02_RS28690	COG0546	phosphoglycolate phosphatase activity
PverR02_RS28695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PverR02_RS28700	COG1454	alcohol dehydrogenase
PverR02_RS28710	COG1176	ABC-type spermidine putrescine transport system, permease component I
PverR02_RS28720	COG3842	ATPase activity
PverR02_RS28725	COG2197	response regulator
PverR02_RS28740	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
PverR02_RS28745	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PverR02_RS28750	COG3178	'Phosphotransferase
PverR02_RS28755	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
PverR02_RS28760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PverR02_RS28765	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PverR02_RS28770	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PverR02_RS28775	COG2967	ApaG domain
PverR02_RS28780	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PverR02_RS28785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PverR02_RS28790	COG2766	serine protein kinase
PverR02_RS28795	COG2718	Belongs to the UPF0229 family
PverR02_RS28800	COG2719	SpoVR family
PverR02_RS28805	COG0617	tRNA 3'-terminal CCA addition
PverR02_RS28815	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PverR02_RS28820	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
PverR02_RS28825	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PverR02_RS28830	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PverR02_RS28835	COG0358	DNA primase activity
PverR02_RS28840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PverR02_RS28860	COG0583	DNA-binding transcription factor activity
PverR02_RS28875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PverR02_RS28880	COG1025	Belongs to the peptidase M16 family
PverR02_RS28890	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PverR02_RS28895	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
PverR02_RS28905	COG0535	radical SAM domain protein
PverR02_RS28915	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PverR02_RS28920	COG0583	DNA-binding transcription factor activity
PverR02_RS28925	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS28930	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS28940	COG1960	acyl-CoA dehydrogenase activity
PverR02_RS28960	COG2226	methyltransferase
PverR02_RS28960	COG1073	alpha beta
PverR02_RS28965	COG0156	8-amino-7-oxononanoate synthase activity
PverR02_RS28970	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PverR02_RS28980	COG3585	molybdate ion transport
PverR02_RS28980	COG2005	Transcriptional regulator
PverR02_RS28990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PverR02_RS29005	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PverR02_RS29010	COG0745	RESPONSE REGULATOR receiver
PverR02_RS29010	COG4566	intracellular signal transduction
PverR02_RS29025	COG1595	DNA-templated transcription, initiation
PverR02_RS29035	COG4774	siderophore transport
PverR02_RS29055	COG4452	Inner membrane protein CreD
PverR02_RS29060	COG2205	protein histidine kinase activity
PverR02_RS29065	COG0745	RESPONSE REGULATOR receiver
PverR02_RS29070	COG0189	ligase activity
PverR02_RS29070	COG4067	protein conserved in archaea
PverR02_RS29075	COG0204	Acyl-transferase
PverR02_RS29100	COG1063	alcohol dehydrogenase
PverR02_RS29130	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PverR02_RS29150	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
PverR02_RS29160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PverR02_RS29160	COG1017	nitric oxide dioxygenase activity
PverR02_RS29180	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PverR02_RS29185	COG0247	lactate metabolic process
PverR02_RS29185	COG2181	nitrate reductase activity
PverR02_RS29190	COG0446	pyridine nucleotide-disulphide oxidoreductase
PverR02_RS29190	COG1902	pentaerythritol trinitrate reductase activity
PverR02_RS29210	COG2304	oxidoreductase activity
PverR02_RS29235	COG3246	L-lysine catabolic process to acetate
PverR02_RS29240	COG1250	3-hydroxyacyl-CoA dehydrogenase
PverR02_RS29260	COG1760	l-serine dehydratase
PverR02_RS29275	COG4175	Glycine betaine
PverR02_RS29280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PverR02_RS29285	COG1309	transcriptional regulator
PverR02_RS29290	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS29295	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PverR02_RS29315	COG0477	Major facilitator Superfamily
PverR02_RS29320	COG0513	Belongs to the DEAD box helicase family
PverR02_RS29325	COG2081	HI0933 family
PverR02_RS29330	COG1289	transmembrane transporter activity
PverR02_RS29340	COG2153	protein acetylation
PverR02_RS29350	COG1451	nucleotide metabolic process
PverR02_RS29380	COG0126	phosphoglycerate kinase activity
PverR02_RS29385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PverR02_RS29390	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PverR02_RS29395	COG0640	Transcriptional regulator
PverR02_RS29400	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PverR02_RS29410	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PverR02_RS29415	COG1422	Protein of unknown function (DUF1090)
PverR02_RS29435	COG2116	formate transmembrane transporter activity
PverR02_RS29450	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PverR02_RS29455	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PverR02_RS29470	COG0513	Belongs to the DEAD box helicase family
PverR02_RS29475	COG2353	YceI-like domain
PverR02_RS29480	COG3038	cytochrome b561
PverR02_RS29490	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PverR02_RS29495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PverR02_RS29510	COG1272	protein, Hemolysin III
PverR02_RS29550	COG3052	prosthetic group binding
PverR02_RS29555	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
PverR02_RS29590	COG0643	Histidine kinase
PverR02_RS29590	COG0784	Response regulator, receiver
PverR02_RS29590	COG2198	Histidine kinase
PverR02_RS29615	COG0189	ligase activity
PverR02_RS29625	COG1678	Uncharacterized ACR, COG1678
PverR02_RS29630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PverR02_RS29635	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PverR02_RS29640	COG0540	Belongs to the ATCase OTCase family
PverR02_RS29645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PverR02_RS29655	COG0791	NLP P60 protein
PverR02_RS29680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PverR02_RS29685	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PverR02_RS29685	COG2813	Specifically methylates the guanine in position
PverR02_RS29695	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PverR02_RS29700	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PverR02_RS29710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PverR02_RS29715	COG2022	thiamine diphosphate biosynthetic process
PverR02_RS29725	COG2363	Small membrane protein
PverR02_RS29730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PverR02_RS29740	COG2177	Part of the ABC transporter FtsEX involved in
PverR02_RS29745	COG2884	Cell division ATP-binding protein ftsE
PverR02_RS29750	COG0552	protein localization to endoplasmic reticulum
PverR02_RS29755	COG0612	Peptidase, M16
PverR02_RS29760	COG0612	Peptidase, M16
PverR02_RS29765	COG0742	ribosomal rna small subunit methyltransferase
PverR02_RS29770	COG0429	hydrolase of the alpha beta-hydrolase fold
PverR02_RS29780	COG1309	transcriptional regulator
PverR02_RS29795	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PverR02_RS29800	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PverR02_RS29805	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PverR02_RS29810	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PverR02_RS29820	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PverR02_RS29825	COG2814	Major facilitator Superfamily
PverR02_RS29835	COG0129	dihydroxy-acid dehydratase activity
PverR02_RS29845	COG1823	symporter activity
PverR02_RS29860	COG1160	GTP binding
PverR02_RS29880	COG1840	ABC-type Fe3 transport system, periplasmic component
PverR02_RS29885	COG1178	ABC-type Fe3 transport system permease component
PverR02_RS29890	COG3842	ATPase activity
PverR02_RS29895	COG0583	DNA-binding transcription factor activity
PverR02_RS29905	COG0789	Transcriptional regulator
PverR02_RS29910	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PverR02_RS29915	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PverR02_RS29920	COG0730	response to heat
PverR02_RS29935	COG0494	nUDIX hydrolase
PverR02_RS29950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PverR02_RS29955	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PverR02_RS29960	COG3204	pilus organization
PverR02_RS29965	COG3204	pilus organization
PverR02_RS29970	COG0179	Fumarylacetoacetate (FAA) hydrolase
PverR02_RS29975	COG0277	FAD linked oxidase domain protein
PverR02_RS29985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PverR02_RS29995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PverR02_RS30000	COG1683	Conserved Protein
PverR02_RS30040	COG1177	transmembrane transport
PverR02_RS30045	COG1177	transmembrane transport
PverR02_RS30050	COG1176	ABC-type spermidine putrescine transport system, permease component I
PverR02_RS30055	COG3842	ATPase activity
PverR02_RS30075	COG0174	glutamine synthetase
PverR02_RS30085	COG0174	glutamine synthetase
PverR02_RS30100	COG1116	anion transmembrane transporter activity
PverR02_RS30105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PverR02_RS30110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PverR02_RS30115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PverR02_RS30120	COG0431	NADPH-dependent FMN reductase
PverR02_RS30125	COG0450	alkyl hydroperoxide reductase
PverR02_RS30135	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PverR02_RS30135	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PverR02_RS30150	COG1522	sequence-specific DNA binding
PverR02_RS30160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PverR02_RS30165	COG0330	HflC and HflK could
PverR02_RS30185	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PverR02_RS30190	COG0509	glycine decarboxylation via glycine cleavage system
PverR02_RS30195	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PverR02_RS30200	COG1178	ABC-type Fe3 transport system permease component
PverR02_RS30210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PverR02_RS30215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PverR02_RS30220	COG0006	proline dipeptidase activity
PverR02_RS30225	COG3079	Belongs to the UPF0149 family
PverR02_RS30245	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PverR02_RS30255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PverR02_RS30260	COG1129	ABC transporter
PverR02_RS30260	COG0842	Transport permease protein
PverR02_RS30265	COG0842	Transport permease protein
PverR02_RS30295	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PverR02_RS30315	COG2186	Transcriptional regulator
PverR02_RS30320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PverR02_RS30325	COG0765	amino acid transport
PverR02_RS30330	COG0765	amino acid transport
PverR02_RS30335	COG1126	abc transporter atp-binding protein
PverR02_RS30345	COG3188	usher protein
PverR02_RS30350	COG3121	Chaperone
PverR02_RS30360	COG0248	Ppx GppA phosphatase
PverR02_RS30365	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PverR02_RS30375	COG0586	Pfam SNARE associated Golgi protein
PverR02_RS30385	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
PverR02_RS30390	COG1671	Belongs to the UPF0178 family
PverR02_RS30395	COG0672	)-iron permease
PverR02_RS30400	COG1280	lysine exporter protein (LysE YggA)
PverR02_RS30410	COG0488	(ABC) transporter
PverR02_RS30435	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
PverR02_RS30450	COG0181	hydroxymethylbilane synthase activity
PverR02_RS30460	COG0165	Argininosuccinate lyase
PverR02_RS30465	COG0625	glutathione transferase activity
PverR02_RS30485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PverR02_RS30495	COG1965	Belongs to the frataxin family
PverR02_RS30510	COG0019	diaminopimelate decarboxylase activity
PverR02_RS30515	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PverR02_RS30525	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PverR02_RS30530	COG1011	Hydrolase
PverR02_RS30540	COG0432	Pfam Uncharacterised protein family UPF0047
PverR02_RS30545	COG0004	ammonium transporteR
PverR02_RS30550	COG0347	Belongs to the P(II) protein family
PverR02_RS30560	COG0606	chelatase, subunit chli
PverR02_RS30565	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PverR02_RS30575	COG3135	benzoate transporter
PverR02_RS30585	COG0840	transmembrane signaling receptor activity
PverR02_RS30590	COG0583	DNA-binding transcription factor activity
PverR02_RS30595	COG0534	Mate efflux family protein
PverR02_RS30610	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PverR02_RS30615	COG0427	acetyl-CoA hydrolase
PverR02_RS30630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PverR02_RS30635	COG0251	oxidation-reduction process
PverR02_RS30640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PverR02_RS30655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PverR02_RS30665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PverR02_RS30670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PverR02_RS30680	COG1012	belongs to the aldehyde dehydrogenase family
PverR02_RS30690	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PverR02_RS30695	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PverR02_RS30700	COG0747	negative chemotaxis
PverR02_RS30705	COG2003	Belongs to the UPF0758 family
PverR02_RS30710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PverR02_RS30715	COG0756	dUTP diphosphatase activity
PverR02_RS30725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PverR02_RS30730	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PverR02_RS30735	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PverR02_RS30740	COG0708	Exodeoxyribonuclease III
PverR02_RS30750	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PverR02_RS30755	COG1561	YicC-like family, N-terminal region
PverR02_RS30760	COG0194	GDP metabolic process
PverR02_RS30765	COG1758	RNA polymerase activity
PverR02_RS30770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PverR02_RS30795	COG0848	biopolymer transport protein
PverR02_RS30805	COG0583	DNA-binding transcription factor activity
PverR02_RS30810	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PverR02_RS30845	COG1136	(ABC) transporter
PverR02_RS30850	COG0515	serine threonine protein kinase
PverR02_RS30850	COG2815	serine threonine protein kinase
PverR02_RS30950	COG3209	COG3209 Rhs family protein
PverR02_RS30960	COG3209	COG3209 Rhs family protein
PverR02_RS30990	COG3161	chorismate lyase activity
PverR02_RS30995	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PverR02_RS31015	COG1253	flavin adenine dinucleotide binding
PverR02_RS31020	COG0739	heme binding
PverR02_RS31030	COG0704	Plays a role in the regulation of phosphate uptake
PverR02_RS31035	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PverR02_RS31040	COG0573	inorganic phosphate transmembrane transporter activity
PverR02_RS31055	COG0477	Major facilitator Superfamily
PverR02_RS31060	COG1607	acyl-coa hydrolase
PverR02_RS31065	COG0676	glucose-6-phosphate 1-epimerase activity
PverR02_RS31090	COG0583	DNA-binding transcription factor activity
PverR02_RS31095	COG1027	Aspartate ammonia-lyase
PverR02_RS31100	COG1115	amino acid carrier protein
PverR02_RS31105	COG0252	asparaginase activity
PverR02_RS31165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PverR02_RS31170	COG0765	amino acid transport
PverR02_RS31190	COG5016	pyruvate
PverR02_RS31190	COG0511	ligase activity, forming carbon-carbon bonds
PverR02_RS31195	COG0439	Biotin carboxylase
PverR02_RS31200	COG0583	DNA-binding transcription factor activity
PverR02_RS31220	COG0210	DNA helicase
PverR02_RS31235	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PverR02_RS31235	COG4651	solute:proton antiporter activity
PverR02_RS31240	COG1607	acyl-coa hydrolase
PverR02_RS31245	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
PverR02_RS31255	COG0523	cobalamin synthesis protein
PverR02_RS31275	COG0860	N-Acetylmuramoyl-L-alanine amidase
PverR02_RS31280	COG1469	GTP cyclohydrolase I activity
PverR02_RS31285	COG1121	(ABC) transporter
PverR02_RS31305	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PverR02_RS31315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PverR02_RS31320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PverR02_RS31330	COG3220	belongs to the UPF0276 family
PverR02_RS31360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PverR02_RS31365	COG2267	carboxylic ester hydrolase activity
PverR02_RS31370	COG2453	phosphatase
PverR02_RS31370	COG0671	phosphoesterase, PA-phosphatase related
PverR02_RS31385	COG4589	Belongs to the CDS family
PverR02_RS31390	COG2373	Large extracellular alpha-helical protein
PverR02_RS31395	COG4953	penicillin-binding protein 1C
PverR02_RS31420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PverR02_RS31425	COG1349	DNA-binding transcription factor activity
PverR02_RS31430	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PverR02_RS31435	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PverR02_RS31440	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PverR02_RS31445	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PverR02_RS31450	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PverR02_RS31455	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PverR02_RS31460	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PverR02_RS31470	COG0356	it plays a direct role in the translocation of protons across the membrane
PverR02_RS31475	COG3312	ion transport
PverR02_RS31480	COG1475	DNA binding
PverR02_RS31485	COG1192	Involved in chromosome partitioning
PverR02_RS31490	COG0357	Ribosomal RNA small subunit methyltransferase G
PverR02_RS31495	COG0445	tRNA wobble uridine modification
PverR02_RS31505	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PverR02_RS31510	COG0706	membrane insertase activity
PverR02_RS31515	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PverR02_RS31520	COG0594	ribonuclease P activity
PverR02_RS31525	COG0230	Belongs to the bacterial ribosomal protein bL34 family