locus-tag	class	description
PSED_RS00010	COG0592	DNA-directed DNA polymerase activity
PSED_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PSED_RS00020	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
PSED_RS00025	COG0187	DNA topoisomerase II activity
PSED_RS00075	COG4584	PFAM Integrase catalytic
PSED_RS00080	COG1484	DNA-dependent DNA replication
PSED_RS00085	COG3328	transposase activity
PSED_RS00095	COG1335	isochorismatase
PSED_RS00170	COG3344	reverse transcriptase
PSED_RS00180	COG0640	Transcriptional regulator
PSED_RS00185	COG2217	Heavy metal translocating P-type atpase
PSED_RS00240	COG3328	transposase activity
PSED_RS00245	COG1316	TRANSCRIPTIONal
PSED_RS00275	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PSED_RS00280	COG2826	transposase and inactivated derivatives, IS30 family
PSED_RS00290	COG1289	transmembrane transporter activity
PSED_RS00310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PSED_RS00325	COG2271	Major facilitator Superfamily
PSED_RS00355	COG1414	Transcriptional regulator
PSED_RS00375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSED_RS00395	COG2201	protein-glutamate methylesterase activity
PSED_RS00415	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PSED_RS00440	COG3795	YCII-related domain
PSED_RS00445	COG4941	Belongs to the sigma-70 factor family
PSED_RS00450	COG2860	membrane
PSED_RS00460	COG2186	Transcriptional regulator
PSED_RS00470	COG1063	alcohol dehydrogenase
PSED_RS00475	COG2079	MmgE PrpD family protein
PSED_RS00520	COG0705	Rhomboid family
PSED_RS00520	COG0457	Tetratricopeptide repeat
PSED_RS00540	COG0515	serine threonine protein kinase
PSED_RS00540	COG2815	serine threonine protein kinase
PSED_RS00545	COG0515	serine threonine protein kinase
PSED_RS00550	COG0768	penicillin binding
PSED_RS00565	COG1716	ATPase activity
PSED_RS00570	COG1716	ATPase activity
PSED_RS00605	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PSED_RS00650	COG0702	epimerase
PSED_RS00655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PSED_RS00690	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PSED_RS00695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PSED_RS00725	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PSED_RS00730	COG3275	phosphorelay sensor kinase activity
PSED_RS00740	COG3279	Response regulator of the LytR AlgR family
PSED_RS00750	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PSED_RS00755	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PSED_RS00780	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS00790	COG1566	PFAM secretion protein HlyD family protein
PSED_RS00795	COG2814	Major facilitator Superfamily
PSED_RS00815	COG0406	alpha-ribazole phosphatase activity
PSED_RS00835	COG0754	glutathionylspermidine amidase activity
PSED_RS00840	COG3766	membrane
PSED_RS00845	COG0561	phosphatase activity
PSED_RS00855	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PSED_RS00860	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PSED_RS00885	COG1216	Glycosyl transferase, family 2
PSED_RS00920	COG1216	Glycosyl transferase, family 2
PSED_RS00925	COG1216	Glycosyl transferase, family 2
PSED_RS00945	COG0778	Nitroreductase
PSED_RS00960	COG0277	FAD linked oxidase domain protein
PSED_RS00980	COG1131	(ABC) transporter
PSED_RS01015	COG1216	Glycosyl transferase, family 2
PSED_RS01035	COG3321	synthase
PSED_RS01035	COG0604	alcohol dehydrogenase
PSED_RS01035	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS01060	COG2267	carboxylic ester hydrolase activity
PSED_RS01070	COG2368	4-hydroxyphenylacetate
PSED_RS01135	COG1362	aminopeptidase activity
PSED_RS01145	COG0339	signal peptide processing
PSED_RS01150	COG0745	RESPONSE REGULATOR receiver
PSED_RS01160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PSED_RS01165	COG0412	Dienelactone hydrolase
PSED_RS01170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PSED_RS01220	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PSED_RS01225	COG3384	dioxygenase
PSED_RS01235	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PSED_RS01240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PSED_RS01250	COG3486	L-lysine 6-monooxygenase (NADPH) activity
PSED_RS01255	COG1132	(ABC) transporter
PSED_RS01260	COG1132	(ABC) transporter
PSED_RS01275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PSED_RS01280	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PSED_RS01320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS01350	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PSED_RS01350	COG2010	Cytochrome c
PSED_RS01385	COG2706	6-phosphogluconolactonase activity
PSED_RS01400	COG0678	peroxiredoxin activity
PSED_RS01410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PSED_RS01415	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PSED_RS01420	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
PSED_RS01475	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS01485	COG1024	Enoyl-CoA hydratase
PSED_RS01505	COG0667	Aldo Keto reductase
PSED_RS01510	COG1454	alcohol dehydrogenase
PSED_RS01525	COG3328	transposase activity
PSED_RS01535	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PSED_RS01540	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PSED_RS01545	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PSED_RS01585	COG2197	response regulator
PSED_RS01590	COG4585	Histidine kinase
PSED_RS01610	COG1309	transcriptional regulator
PSED_RS01635	COG1316	TRANSCRIPTIONal
PSED_RS01640	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PSED_RS01660	COG0287	Prephenate dehydrogenase
PSED_RS01670	COG1473	amidohydrolase
PSED_RS01680	COG0590	tRNA wobble adenosine to inosine editing
PSED_RS01685	COG0494	nUDIX hydrolase
PSED_RS01705	COG2814	Major facilitator Superfamily
PSED_RS01725	COG0402	S-adenosylhomocysteine deaminase activity
PSED_RS01730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PSED_RS01735	COG0179	Fumarylacetoacetate (FAA) hydrolase
PSED_RS01740	COG2186	Transcriptional regulator
PSED_RS01760	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PSED_RS01770	COG0583	DNA-binding transcription factor activity
PSED_RS01780	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PSED_RS01785	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PSED_RS01855	COG1393	Belongs to the ArsC family
PSED_RS01880	COG1309	transcriptional regulator
PSED_RS01895	COG4941	Belongs to the sigma-70 factor family
PSED_RS01950	COG4977	sequence-specific DNA binding
PSED_RS01975	COG1408	metallophosphoesterase
PSED_RS01985	COG1754	DNA topoisomerase type I activity
PSED_RS01985	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PSED_RS02005	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
PSED_RS02010	COG1111	helicase
PSED_RS02010	COG1205	dead DEAH box helicase
PSED_RS02055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PSED_RS02070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSED_RS02075	COG0714	Associated with various cellular activities
PSED_RS02090	COG2304	oxidoreductase activity
PSED_RS02095	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PSED_RS02100	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PSED_RS02110	COG0596	Alpha beta hydrolase
PSED_RS02115	COG0584	glycerophosphoryl diester phosphodiesterase
PSED_RS02125	COG0583	DNA-binding transcription factor activity
PSED_RS02135	COG0436	Aminotransferase
PSED_RS02140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PSED_RS02160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PSED_RS02165	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PSED_RS02180	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
PSED_RS02185	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PSED_RS02190	COG0047	phosphoribosylformylglycinamidine synthase activity
PSED_RS02200	COG4251	negative regulation of phosphorylation
PSED_RS02205	COG0784	Response regulator, receiver
PSED_RS02210	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PSED_RS02240	COG1725	Transcriptional regulator
PSED_RS02260	COG0354	folic acid binding
PSED_RS02265	COG0735	belongs to the Fur family
PSED_RS02315	COG0745	RESPONSE REGULATOR receiver
PSED_RS02320	COG0456	acetyltransferase
PSED_RS02320	COG0454	-acetyltransferase
PSED_RS02340	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PSED_RS02405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PSED_RS02410	COG2814	Major facilitator Superfamily
PSED_RS02415	COG1090	epimerase
PSED_RS02425	COG0477	Major facilitator Superfamily
PSED_RS02510	COG0640	Transcriptional regulator
PSED_RS02515	COG3547	Transposase (IS116 IS110 IS902 family)
PSED_RS02520	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS02525	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS02535	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PSED_RS02560	COG1309	transcriptional regulator
PSED_RS02565	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PSED_RS02600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS02620	COG1960	acyl-CoA dehydrogenase activity
PSED_RS02645	COG1960	acyl-CoA dehydrogenase activity
PSED_RS02650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PSED_RS02650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PSED_RS02700	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
PSED_RS02710	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS02730	COG0167	dihydroorotate dehydrogenase activity
PSED_RS02755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PSED_RS02770	COG2267	carboxylic ester hydrolase activity
PSED_RS02790	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PSED_RS02805	COG1643	Atp-dependent helicase
PSED_RS02835	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS02860	COG2217	Heavy metal translocating P-type atpase
PSED_RS02865	COG1937	Protein conserved in bacteria
PSED_RS02935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PSED_RS02955	COG1278	Cold shock
PSED_RS02965	COG2733	membrane
PSED_RS02980	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PSED_RS02985	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PSED_RS03010	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PSED_RS03020	COG2814	Major facilitator Superfamily
PSED_RS03030	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PSED_RS03055	COG2252	PERMEase
PSED_RS03090	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PSED_RS03100	COG0259	pyridoxamine-phosphate oxidase activity
PSED_RS03105	COG2814	Major facilitator Superfamily
PSED_RS03135	COG1668	transmembrane transport
PSED_RS03140	COG4152	abc transporter atp-binding protein
PSED_RS03145	COG2186	Transcriptional regulator
PSED_RS03155	COG2267	carboxylic ester hydrolase activity
PSED_RS03160	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS03170	COG2358	TRAP transporter, solute receptor (TAXI family
PSED_RS03195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PSED_RS03210	COG0459	protein refolding
PSED_RS03220	COG0477	Major facilitator Superfamily
PSED_RS03230	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PSED_RS03230	COG0235	Class ii aldolase
PSED_RS03245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PSED_RS03280	COG0789	Transcriptional regulator
PSED_RS03285	COG0183	Belongs to the thiolase family
PSED_RS03290	COG1024	Enoyl-CoA hydratase
PSED_RS03290	COG1250	3-hydroxyacyl-CoA dehydrogenase
PSED_RS03295	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
PSED_RS03315	COG4133	protoheme IX ABC transporter activity
PSED_RS03330	COG0701	Predicted permease
PSED_RS03360	COG0477	Major facilitator Superfamily
PSED_RS03365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PSED_RS03375	COG4948	Mandelate Racemase Muconate Lactonizing
PSED_RS03380	COG0583	DNA-binding transcription factor activity
PSED_RS03390	COG5006	permease, DMT superfamily
PSED_RS03415	COG3706	GGDEF domain
PSED_RS03420	COG1733	regulation of RNA biosynthetic process
PSED_RS03425	COG1960	acyl-CoA dehydrogenase activity
PSED_RS03430	COG2318	DinB family
PSED_RS03455	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSED_RS03470	COG1129	ABC transporter
PSED_RS03480	COG0252	asparaginase activity
PSED_RS03485	COG0473	3-isopropylmalate dehydrogenase activity
PSED_RS03490	COG2814	Major facilitator Superfamily
PSED_RS03495	COG0739	heme binding
PSED_RS03495	COG1196	nuclear chromosome segregation
PSED_RS03495	COG0741	lytic transglycosylase activity
PSED_RS03515	COG0583	DNA-binding transcription factor activity
PSED_RS03520	COG0473	3-isopropylmalate dehydrogenase activity
PSED_RS03530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PSED_RS03535	COG3795	YCII-related domain
PSED_RS03540	COG4941	Belongs to the sigma-70 factor family
PSED_RS03555	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PSED_RS03560	COG2409	Drug exporters of the RND superfamily
PSED_RS03675	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PSED_RS03690	COG1960	acyl-CoA dehydrogenase activity
PSED_RS03695	COG1959	2 iron, 2 sulfur cluster binding
PSED_RS03710	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PSED_RS03730	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PSED_RS03735	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
PSED_RS03740	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
PSED_RS03745	COG0535	radical SAM domain protein
PSED_RS03750	COG1971	Probably functions as a manganese efflux pump
PSED_RS03760	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
PSED_RS03780	COG0745	RESPONSE REGULATOR receiver
PSED_RS03785	COG2205	protein histidine kinase activity
PSED_RS03815	COG3260	NADH ubiquinone oxidoreductase 20
PSED_RS03825	COG0650	Formate hydrogenlyase subunit 4
PSED_RS03835	COG0651	ATP synthesis coupled electron transport
PSED_RS03840	COG3261	NADH dehydrogenase
PSED_RS03840	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
PSED_RS03855	COG4829	muconolactone delta-isomerase
PSED_RS03860	COG3485	protocatechuate 3,4-dioxygenase
PSED_RS03870	COG2871	sodium ion transport
PSED_RS03900	COG0583	DNA-binding transcription factor activity
PSED_RS03905	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PSED_RS03910	COG1595	DNA-templated transcription, initiation
PSED_RS03925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PSED_RS03935	COG0183	Belongs to the thiolase family
PSED_RS03940	COG0583	DNA-binding transcription factor activity
PSED_RS03955	COG2226	methyltransferase
PSED_RS03960	COG1408	metallophosphoesterase
PSED_RS03965	COG2084	Dehydrogenase
PSED_RS03970	COG0745	RESPONSE REGULATOR receiver
PSED_RS03975	COG2205	protein histidine kinase activity
PSED_RS03980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSED_RS04000	COG0583	DNA-binding transcription factor activity
PSED_RS04025	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PSED_RS04030	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PSED_RS04065	COG0022	dehydrogenase e1 component
PSED_RS04070	COG0508	dehydrogenase complex catalyzes the overall conversion of
PSED_RS04085	COG2151	metal-sulfur cluster biosynthetic enzyme
PSED_RS04115	COG3350	monooxygenase activity
PSED_RS04145	COG4948	Mandelate Racemase Muconate Lactonizing
PSED_RS04180	COG0475	glutathione-regulated potassium exporter activity
PSED_RS04205	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PSED_RS04210	COG0084	hydrolase, TatD family'
PSED_RS04220	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PSED_RS04235	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PSED_RS04240	COG0488	(ABC) transporter
PSED_RS04275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PSED_RS04280	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS04285	COG0193	aminoacyl-tRNA hydrolase activity
PSED_RS04320	COG1674	ftsk spoiiie
PSED_RS04360	COG3328	transposase activity
PSED_RS04405	COG4974	Belongs to the 'phage' integrase family
PSED_RS04415	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PSED_RS04450	COG0793	Belongs to the peptidase S41A family
PSED_RS04450	COG4946	Tricorn protease homolog
PSED_RS04455	COG1131	(ABC) transporter
PSED_RS04470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PSED_RS04485	COG2837	iron assimilation
PSED_RS04495	COG0672	)-iron permease
PSED_RS04500	COG0672	)-iron permease
PSED_RS04510	COG2837	iron assimilation
PSED_RS04520	COG0148	phosphopyruvate hydratase activity
PSED_RS04535	COG1960	acyl-CoA dehydrogenase activity
PSED_RS04550	COG1252	NADH dehydrogenase
PSED_RS04630	COG0640	Transcriptional regulator
PSED_RS04645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PSED_RS04685	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS04690	COG1960	acyl-CoA dehydrogenase activity
PSED_RS04705	COG0183	Belongs to the thiolase family
PSED_RS04715	COG3795	YCII-related domain
PSED_RS04720	COG4941	Belongs to the sigma-70 factor family
PSED_RS04750	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PSED_RS04755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PSED_RS04760	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PSED_RS04775	COG1331	Highly conserved protein containing a thioredoxin domain
PSED_RS04810	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
PSED_RS04825	COG1793	dna ligase
PSED_RS04835	COG0114	fumarate hydratase activity
PSED_RS04860	COG1570	exodeoxyribonuclease VII activity
PSED_RS04870	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PSED_RS04880	COG1322	Protein conserved in bacteria
PSED_RS04885	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PSED_RS04885	COG2169	Transcriptional regulator
PSED_RS04900	COG0012	GTP binding
PSED_RS04935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS04940	COG3973	AAA domain
PSED_RS04955	COG0640	Transcriptional regulator
PSED_RS04970	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PSED_RS04985	COG2154	pterin-4-alpha-carbinolamine dehydratase
PSED_RS04995	COG1131	(ABC) transporter
PSED_RS05030	COG1217	gtp-binding protein TYPA
PSED_RS05035	COG0747	negative chemotaxis
PSED_RS05040	COG4166	transmembrane transport
PSED_RS05045	COG0601	transmembrane transport
PSED_RS05050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSED_RS05060	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PSED_RS05105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PSED_RS05110	COG1611	Belongs to the LOG family
PSED_RS05115	COG1611	Belongs to the LOG family
PSED_RS05120	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PSED_RS05125	COG0463	Glycosyl transferase, family 2
PSED_RS05140	COG0519	Catalyzes the synthesis of GMP from XMP
PSED_RS05150	COG0297	glycogen (starch) synthase activity
PSED_RS05155	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PSED_RS05175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSED_RS05180	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PSED_RS05190	COG0154	amidase activity
PSED_RS05195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PSED_RS05215	COG2186	Transcriptional regulator
PSED_RS05225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PSED_RS05245	COG2239	Acts as a magnesium transporter
PSED_RS05250	COG0384	phenazine biosynthesis protein PhzF
PSED_RS05255	COG2301	Belongs to the HpcH HpaI aldolase family
PSED_RS05260	COG1960	acyl-CoA dehydrogenase activity
PSED_RS05300	COG2826	transposase and inactivated derivatives, IS30 family
PSED_RS05315	COG2226	methyltransferase
PSED_RS05325	COG0598	Magnesium transport protein CorA
PSED_RS05335	COG1051	belongs to the nudix hydrolase family
PSED_RS05345	COG0613	PHP domain protein
PSED_RS05365	COG0513	Belongs to the DEAD box helicase family
PSED_RS05390	COG1126	abc transporter atp-binding protein
PSED_RS05420	COG1309	transcriptional regulator
PSED_RS05455	COG2223	nitrite transmembrane transporter activity
PSED_RS05460	COG0243	molybdopterin cofactor binding
PSED_RS05465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSED_RS05470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSED_RS05470	COG2146	nitrite reductase [NAD(P)H] activity
PSED_RS05495	COG0596	Alpha beta hydrolase
PSED_RS05500	COG0210	DNA helicase
PSED_RS05525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PSED_RS05530	COG1846	Transcriptional regulator
PSED_RS05530	COG1940	carbohydrate kinase activity
PSED_RS05535	COG1070	Carbohydrate kinase
PSED_RS05540	COG2115	Belongs to the xylose isomerase family
PSED_RS05545	COG0708	Exodeoxyribonuclease III
PSED_RS05560	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PSED_RS05565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSED_RS05610	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PSED_RS05630	COG1615	UPF0182 protein
PSED_RS05640	COG0582	viral genome integration into host DNA
PSED_RS05660	COG1674	ftsk spoiiie
PSED_RS05680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PSED_RS05715	COG1595	DNA-templated transcription, initiation
PSED_RS05730	COG3328	transposase activity
PSED_RS05740	COG3328	transposase activity
PSED_RS05750	COG3328	transposase activity
PSED_RS05825	COG3835	regulator
PSED_RS05830	COG0583	DNA-binding transcription factor activity
PSED_RS05840	COG0640	Transcriptional regulator
PSED_RS05845	COG0346	lactoylglutathione lyase activity
PSED_RS05860	COG3875	lactate racemase activity
PSED_RS05875	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PSED_RS05880	COG2755	lipolytic protein G-D-S-L family
PSED_RS05880	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PSED_RS05890	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PSED_RS05895	COG4221	oxidoreductase activity
PSED_RS05915	COG2365	Tyrosine phosphatase family
PSED_RS05930	COG1960	acyl-CoA dehydrogenase activity
PSED_RS05935	COG1960	acyl-CoA dehydrogenase activity
PSED_RS05945	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PSED_RS05950	COG2884	Cell division ATP-binding protein ftsE
PSED_RS05955	COG2177	Part of the ABC transporter FtsEX involved in
PSED_RS05960	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PSED_RS05985	COG1335	isochorismatase
PSED_RS05995	COG2188	Transcriptional regulator
PSED_RS06020	COG4946	Tricorn protease homolog
PSED_RS06020	COG1506	peptidase
PSED_RS06020	COG0823	Involved in the tonB-independent uptake of proteins
PSED_RS06025	COG3547	Transposase (IS116 IS110 IS902 family)
PSED_RS06085	COG3547	Transposase (IS116 IS110 IS902 family)
PSED_RS06130	COG0791	NLP P60 protein
PSED_RS06150	COG0758	DNA mediated transformation
PSED_RS06245	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PSED_RS06275	COG0483	inositol monophosphate 1-phosphatase activity
PSED_RS06355	COG1595	DNA-templated transcription, initiation
PSED_RS06415	COG2226	methyltransferase
PSED_RS06475	COG0789	Transcriptional regulator
PSED_RS06495	COG1309	transcriptional regulator
PSED_RS06535	COG2608	mercury ion transmembrane transporter activity
PSED_RS06560	COG1595	DNA-templated transcription, initiation
PSED_RS06615	COG1051	belongs to the nudix hydrolase family
PSED_RS06640	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
PSED_RS06645	COG1396	sequence-specific DNA binding
PSED_RS06660	COG0183	Belongs to the thiolase family
PSED_RS06670	COG3835	regulator
PSED_RS06680	COG0391	Required for morphogenesis under gluconeogenic growth conditions
PSED_RS06690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS06695	COG0179	Fumarylacetoacetate (FAA) hydrolase
PSED_RS06700	COG2423	ornithine cyclodeaminase activity
PSED_RS06705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PSED_RS06730	COG0405	Gamma-glutamyltransferase
PSED_RS06750	COG1960	acyl-CoA dehydrogenase activity
PSED_RS06755	COG1960	acyl-CoA dehydrogenase activity
PSED_RS06770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS06775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS06790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSED_RS06815	COG1802	Transcriptional regulator
PSED_RS06830	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS06845	COG2072	flavoprotein involved in K transport
PSED_RS06850	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PSED_RS06850	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PSED_RS06895	COG3383	formate dehydrogenase (NAD+) activity
PSED_RS06900	COG0596	Alpha beta hydrolase
PSED_RS06945	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
PSED_RS06970	COG0477	Major facilitator Superfamily
PSED_RS07030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PSED_RS07050	COG0438	transferase activity, transferring glycosyl groups
PSED_RS07070	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PSED_RS07100	COG3954	Phosphoribulokinase
PSED_RS07105	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PSED_RS07110	COG0154	amidase activity
PSED_RS07125	COG0783	Belongs to the Dps family
PSED_RS07140	COG1872	DUF167
PSED_RS07160	COG0393	Putative heavy-metal-binding
PSED_RS07165	COG0393	Putative heavy-metal-binding
PSED_RS07195	COG3350	monooxygenase activity
PSED_RS07225	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PSED_RS07230	COG2151	metal-sulfur cluster biosynthetic enzyme
PSED_RS07240	COG3655	Transcriptional regulator
PSED_RS07250	COG0138	bifunctional purine biosynthesis protein purh
PSED_RS07305	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS07335	COG1053	succinate dehydrogenase
PSED_RS07380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS07385	COG1053	succinate dehydrogenase
PSED_RS07385	COG3976	FMN-binding domain protein
PSED_RS07395	COG0673	inositol 2-dehydrogenase activity
PSED_RS07430	COG1228	amidohydrolase
PSED_RS07435	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS07440	COG1378	Sugar-specific transcriptional regulator TrmB
PSED_RS07480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PSED_RS07485	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PSED_RS07535	COG1335	isochorismatase
PSED_RS07540	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PSED_RS07545	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
PSED_RS07580	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PSED_RS07610	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PSED_RS07615	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PSED_RS07620	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PSED_RS07650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSED_RS07675	COG1366	Belongs to the anti-sigma-factor antagonist family
PSED_RS07685	COG1921	L-seryl-tRNASec selenium transferase activity
PSED_RS07690	COG0709	Synthesizes selenophosphate from selenide and ATP
PSED_RS07710	COG1366	Belongs to the anti-sigma-factor antagonist family
PSED_RS07720	COG1136	(ABC) transporter
PSED_RS07720	COG0577	efflux transmembrane transporter activity
PSED_RS07745	COG0508	dehydrogenase complex catalyzes the overall conversion of
PSED_RS07750	COG0439	Biotin carboxylase
PSED_RS07755	COG5016	pyruvate
PSED_RS07755	COG0511	ligase activity, forming carbon-carbon bonds
PSED_RS07770	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS07780	COG0574	Belongs to the PEP-utilizing enzyme family
PSED_RS07780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PSED_RS07785	COG0183	Belongs to the thiolase family
PSED_RS07795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSED_RS07800	COG0446	pyridine nucleotide-disulphide oxidoreductase
PSED_RS07800	COG1902	pentaerythritol trinitrate reductase activity
PSED_RS07815	COG2197	response regulator
PSED_RS07820	COG3547	Transposase (IS116 IS110 IS902 family)
PSED_RS07835	COG1414	Transcriptional regulator
PSED_RS07845	COG3485	protocatechuate 3,4-dioxygenase
PSED_RS07850	COG3485	protocatechuate 3,4-dioxygenase
PSED_RS07865	COG0300	oxidoreductase activity
PSED_RS07870	COG0427	acetyl-CoA hydrolase
PSED_RS07875	COG0435	Glutathione S-transferase
PSED_RS07880	COG1472	Belongs to the glycosyl hydrolase 3 family
PSED_RS07945	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
PSED_RS07955	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS07960	COG0657	acetylesterase activity
PSED_RS07975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSED_RS08000	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS08015	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS08035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PSED_RS08045	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS08050	COG1024	Enoyl-CoA hydratase
PSED_RS08055	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS08060	COG1024	Enoyl-CoA hydratase
PSED_RS08100	COG1691	(AIR) carboxylase
PSED_RS08135	COG0165	Argininosuccinate lyase
PSED_RS08140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSED_RS08180	COG1846	Transcriptional regulator
PSED_RS08205	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PSED_RS08245	COG0205	6-phosphofructokinase activity
PSED_RS08250	COG0740	serine-type endopeptidase activity
PSED_RS08275	COG1595	DNA-templated transcription, initiation
PSED_RS08315	COG0243	molybdopterin cofactor binding
PSED_RS08340	COG0018	arginyl-trna synthetase
PSED_RS08345	COG0019	diaminopimelate decarboxylase activity
PSED_RS08350	COG0460	homoserine dehydrogenase
PSED_RS08355	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PSED_RS08360	COG0083	homoserine kinase activity
PSED_RS08365	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PSED_RS08375	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PSED_RS08380	COG2890	protein-(glutamine-N5) methyltransferase activity
PSED_RS08395	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PSED_RS08400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PSED_RS08415	COG0356	it plays a direct role in the translocation of protons across the membrane
PSED_RS08420	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PSED_RS08430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PSED_RS08435	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PSED_RS08435	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PSED_RS08440	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PSED_RS08445	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PSED_RS08450	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PSED_RS08455	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PSED_RS08470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PSED_RS08480	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PSED_RS08480	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PSED_RS08495	COG0765	amino acid transport
PSED_RS08500	COG0765	amino acid transport
PSED_RS08505	COG1126	abc transporter atp-binding protein
PSED_RS08510	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PSED_RS08520	COG1309	transcriptional regulator
PSED_RS08555	COG2197	response regulator
PSED_RS08560	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
PSED_RS08565	COG1063	alcohol dehydrogenase
PSED_RS08570	COG1012	belongs to the aldehyde dehydrogenase family
PSED_RS08575	COG1250	3-hydroxyacyl-CoA dehydrogenase
PSED_RS08595	COG0346	lactoylglutathione lyase activity
PSED_RS08600	COG0183	Belongs to the thiolase family
PSED_RS08605	COG1703	isobutyryl-CoA mutase activity
PSED_RS08615	COG1846	Transcriptional regulator
PSED_RS08620	COG2826	transposase and inactivated derivatives, IS30 family
PSED_RS08645	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PSED_RS08655	COG1595	DNA-templated transcription, initiation
PSED_RS08660	COG3281	Trehalose synthase
PSED_RS08665	COG0366	Alpha amylase catalytic
PSED_RS08670	COG0366	Alpha amylase catalytic
PSED_RS08675	COG0058	SHG alpha-glucan phosphorylase activity
PSED_RS08690	COG1119	ATPase activity
PSED_RS08710	COG2197	response regulator
PSED_RS08715	COG2197	response regulator
PSED_RS08725	COG0110	maltose O-acetyltransferase activity
PSED_RS08740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS08745	COG0747	negative chemotaxis
PSED_RS08755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSED_RS08760	COG0444	Belongs to the ABC transporter superfamily
PSED_RS08805	COG4266	Belongs to the allantoicase family
PSED_RS08810	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PSED_RS08820	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PSED_RS08840	COG3835	regulator
PSED_RS08865	COG2233	PERMEase
PSED_RS08900	COG0482	sulfurtransferase activity
PSED_RS08925	COG1960	acyl-CoA dehydrogenase activity
PSED_RS08930	COG1309	transcriptional regulator
PSED_RS08945	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
PSED_RS08990	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PSED_RS08995	COG0154	amidase activity
PSED_RS09040	COG3547	Transposase (IS116 IS110 IS902 family)
PSED_RS09045	COG2072	flavoprotein involved in K transport
PSED_RS09110	COG0129	dihydroxy-acid dehydratase activity
PSED_RS09125	COG0440	acetolactate synthase activity
PSED_RS09130	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PSED_RS09135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS09150	COG0473	3-isopropylmalate dehydrogenase activity
PSED_RS09165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PSED_RS09190	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PSED_RS09195	COG0066	3-isopropylmalate dehydratase activity
PSED_RS09205	COG0494	nUDIX hydrolase
PSED_RS09205	COG0406	alpha-ribazole phosphatase activity
PSED_RS09215	COG1920	GTP binding
PSED_RS09225	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PSED_RS09230	COG0626	cystathionine gamma-synthase activity
PSED_RS09250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PSED_RS09255	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PSED_RS09280	COG0367	asparagine synthase
PSED_RS09320	COG1215	transferase activity, transferring glycosyl groups
PSED_RS09335	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PSED_RS09345	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
PSED_RS09370	COG0745	RESPONSE REGULATOR receiver
PSED_RS09375	COG2205	protein histidine kinase activity
PSED_RS09410	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSED_RS09455	COG1215	transferase activity, transferring glycosyl groups
PSED_RS09470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PSED_RS09475	COG0673	inositol 2-dehydrogenase activity
PSED_RS09480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSED_RS09520	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
PSED_RS09525	COG0517	IMP dehydrogenase activity
PSED_RS09525	COG0516	GMP reductase activity
PSED_RS09540	COG0823	Involved in the tonB-independent uptake of proteins
PSED_RS09540	COG1506	peptidase
PSED_RS09540	COG4946	Tricorn protease homolog
PSED_RS09545	COG0367	asparagine synthase
PSED_RS09550	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
PSED_RS09550	COG2308	Evidence 4 Homologs of previously reported genes of
PSED_RS09650	COG0180	Tryptophanyl-tRNA synthetase
PSED_RS09660	COG0583	DNA-binding transcription factor activity
PSED_RS09710	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PSED_RS09725	COG1064	alcohol dehydrogenase
PSED_RS09730	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PSED_RS09755	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PSED_RS09760	COG1819	glycosyl
PSED_RS09775	COG1280	lysine exporter protein (LysE YggA)
PSED_RS09790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS09820	COG0067	glutamate synthase
PSED_RS09820	COG0069	glutamate synthase activity
PSED_RS09820	COG0070	glutamate synthase
PSED_RS09855	COG0544	peptidyl-prolyl cis-trans isomerase activity
PSED_RS09860	COG0740	serine-type endopeptidase activity
PSED_RS09865	COG0740	serine-type endopeptidase activity
PSED_RS09870	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PSED_RS09905	COG0525	valine-tRNA ligase activity
PSED_RS09910	COG0285	dihydrofolate synthase activity
PSED_RS09925	COG0105	UTP biosynthetic process
PSED_RS09955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PSED_RS09975	COG1530	ribonuclease E activity
PSED_RS09975	COG1530	ribonuclease E activity
PSED_RS09980	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PSED_RS09990	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PSED_RS10005	COG0514	ATP-dependent DNA helicase (RecQ)
PSED_RS10010	COG0542	response to heat
PSED_RS10020	COG0640	Transcriptional regulator
PSED_RS10035	COG3629	intracellular signal transduction
PSED_RS10035	COG3903	Transcriptional regulator
PSED_RS10060	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PSED_RS10065	COG0799	negative regulation of ribosome biogenesis
PSED_RS10075	COG2755	lipolytic protein G-D-S-L family
PSED_RS10080	COG1307	EDD domain protein, DegV family
PSED_RS10085	COG1555	photosystem II stabilization
PSED_RS10085	COG1596	polysaccharide export
PSED_RS10100	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PSED_RS10110	COG0268	Binds directly to 16S ribosomal RNA
PSED_RS10125	COG1119	ATPase activity
PSED_RS10130	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PSED_RS10140	COG0166	Belongs to the GPI family
PSED_RS10170	COG0076	glutamate decarboxylase activity
PSED_RS10180	COG0726	polysaccharide deacetylase
PSED_RS10195	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
PSED_RS10200	COG0254	rRNA binding
PSED_RS10210	COG0038	chloride channel
PSED_RS10250	COG1595	DNA-templated transcription, initiation
PSED_RS10280	COG0640	Transcriptional regulator
PSED_RS10290	COG0076	glutamate decarboxylase activity
PSED_RS10325	COG2837	iron assimilation
PSED_RS10330	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PSED_RS10345	COG2301	Belongs to the HpcH HpaI aldolase family
PSED_RS10350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS10355	COG1609	Transcriptional regulator
PSED_RS10360	COG1309	transcriptional regulator
PSED_RS10370	COG1024	Enoyl-CoA hydratase
PSED_RS10425	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PSED_RS10430	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PSED_RS10435	COG0022	dehydrogenase e1 component
PSED_RS10450	COG1309	transcriptional regulator
PSED_RS10455	COG2072	flavoprotein involved in K transport
PSED_RS10460	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PSED_RS10475	COG3835	regulator
PSED_RS10485	COG0039	L-malate dehydrogenase activity
PSED_RS10490	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
PSED_RS10500	COG1454	alcohol dehydrogenase
PSED_RS10500	COG1012	belongs to the aldehyde dehydrogenase family
PSED_RS10510	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
PSED_RS10525	COG2365	Tyrosine phosphatase family
PSED_RS10530	COG0574	Belongs to the PEP-utilizing enzyme family
PSED_RS10530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PSED_RS10550	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PSED_RS10555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PSED_RS10565	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PSED_RS10570	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PSED_RS10590	COG3835	regulator
PSED_RS10600	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
PSED_RS10600	COG2755	lipolytic protein G-D-S-L family
PSED_RS10610	COG3590	peptidase
PSED_RS10615	COG0477	Major facilitator Superfamily
PSED_RS10625	COG4221	oxidoreductase activity
PSED_RS10635	COG1196	nuclear chromosome segregation
PSED_RS10645	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PSED_RS10650	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PSED_RS10655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PSED_RS10665	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PSED_RS10675	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PSED_RS10680	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PSED_RS10735	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PSED_RS10755	COG1278	Cold shock
PSED_RS10760	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
PSED_RS10800	COG0656	L-ascorbic acid biosynthetic process
PSED_RS10815	COG0604	alcohol dehydrogenase
PSED_RS10865	COG1012	belongs to the aldehyde dehydrogenase family
PSED_RS10875	COG1609	Transcriptional regulator
PSED_RS10885	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PSED_RS10890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS10900	COG2267	carboxylic ester hydrolase activity
PSED_RS10925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS10930	COG1902	pentaerythritol trinitrate reductase activity
PSED_RS10975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSED_RS10985	COG0747	negative chemotaxis
PSED_RS11005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS11010	COG1960	acyl-CoA dehydrogenase activity
PSED_RS11025	COG0583	DNA-binding transcription factor activity
PSED_RS11040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS11045	COG0277	FAD linked oxidase domain protein
PSED_RS11085	COG0443	Heat shock 70 kDa protein
PSED_RS11090	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PSED_RS11105	COG0542	response to heat
PSED_RS11150	COG1454	alcohol dehydrogenase
PSED_RS11155	COG3485	protocatechuate 3,4-dioxygenase
PSED_RS11160	COG2197	response regulator
PSED_RS11170	COG2909	trisaccharide binding
PSED_RS11200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PSED_RS11225	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS11235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PSED_RS11245	COG0024	Methionine aminopeptidase
PSED_RS11260	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS11295	COG0596	Alpha beta hydrolase
PSED_RS11300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PSED_RS11310	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS11320	COG1129	ABC transporter
PSED_RS11325	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSED_RS11340	COG1063	alcohol dehydrogenase
PSED_RS11365	COG0038	chloride channel
PSED_RS11390	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS11410	COG2197	response regulator
PSED_RS11420	COG3485	protocatechuate 3,4-dioxygenase
PSED_RS11425	COG1129	ABC transporter
PSED_RS11445	COG0617	tRNA 3'-terminal CCA addition
PSED_RS11445	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PSED_RS11445	COG3620	sequence-specific DNA binding
PSED_RS11530	COG2860	membrane
PSED_RS11540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PSED_RS11555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PSED_RS11560	COG1846	Transcriptional regulator
PSED_RS11625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS11640	COG1122	ATPase activity
PSED_RS11645	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PSED_RS11650	COG0310	cobalt ion transport
PSED_RS11655	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
PSED_RS11660	COG0450	alkyl hydroperoxide reductase
PSED_RS11670	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PSED_RS11700	COG1295	ribonuclease BN
PSED_RS11740	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS11775	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PSED_RS11795	COG2080	2 iron, 2 sulfur cluster binding
PSED_RS11800	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PSED_RS11805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PSED_RS11825	COG3546	catalase activity
PSED_RS11845	COG2890	protein-(glutamine-N5) methyltransferase activity
PSED_RS11855	COG0747	negative chemotaxis
PSED_RS11865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSED_RS11890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS11990	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PSED_RS12000	COG0783	Belongs to the Dps family
PSED_RS12035	COG3328	transposase activity
PSED_RS12040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PSED_RS12045	COG0798	PFAM Bile acid sodium symporter
PSED_RS12065	COG0640	Transcriptional regulator
PSED_RS12090	COG0437	4 iron, 4 sulfur cluster binding
PSED_RS12095	COG3383	formate dehydrogenase (NAD+) activity
PSED_RS12095	COG0243	molybdopterin cofactor binding
PSED_RS12100	COG3383	formate dehydrogenase (NAD+) activity
PSED_RS12100	COG0243	molybdopterin cofactor binding
PSED_RS12105	COG0655	NAD(P)H dehydrogenase (quinone) activity
PSED_RS12145	COG0028	Belongs to the TPP enzyme family
PSED_RS12150	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PSED_RS12160	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS12165	COG0667	Aldo Keto reductase
PSED_RS12200	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PSED_RS12215	COG2072	flavoprotein involved in K transport
PSED_RS12240	COG1024	Enoyl-CoA hydratase
PSED_RS12255	COG1335	isochorismatase
PSED_RS12265	COG0154	amidase activity
PSED_RS12320	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS12325	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PSED_RS12345	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PSED_RS12350	COG1802	Transcriptional regulator
PSED_RS12355	COG0667	Aldo Keto reductase
PSED_RS12385	COG0179	Fumarylacetoacetate (FAA) hydrolase
PSED_RS12430	COG1309	transcriptional regulator
PSED_RS12450	COG0328	RNA-DNA hybrid ribonuclease activity
PSED_RS12490	COG3246	L-lysine catabolic process to acetate
PSED_RS12525	COG1024	Enoyl-CoA hydratase
PSED_RS12545	COG0583	DNA-binding transcription factor activity
PSED_RS12555	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
PSED_RS12570	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS12575	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
PSED_RS12585	COG3848	Pyruvate phosphate dikinase
PSED_RS12585	COG0574	Belongs to the PEP-utilizing enzyme family
PSED_RS12595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS12600	COG1414	Transcriptional regulator
PSED_RS12605	COG4638	Rieske (2fe-2S)
PSED_RS12620	COG1942	4-Oxalocrotonate Tautomerase
PSED_RS12630	COG3971	2-oxopent-4-enoate hydratase activity
PSED_RS12635	COG1414	Transcriptional regulator
PSED_RS12685	COG2124	cytochrome p450
PSED_RS12690	COG0183	Belongs to the thiolase family
PSED_RS12710	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS12715	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
PSED_RS12740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PSED_RS12755	COG2186	Transcriptional regulator
PSED_RS12770	COG0509	glycine decarboxylation via glycine cleavage system
PSED_RS12775	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PSED_RS12780	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PSED_RS12780	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PSED_RS12785	COG1132	(ABC) transporter
PSED_RS12800	COG3246	L-lysine catabolic process to acetate
PSED_RS12840	COG1024	Enoyl-CoA hydratase
PSED_RS12850	COG1053	succinate dehydrogenase
PSED_RS12860	COG0559	Belongs to the binding-protein-dependent transport system permease family
PSED_RS12875	COG0183	Belongs to the thiolase family
PSED_RS12885	COG1024	Enoyl-CoA hydratase
PSED_RS12900	COG2186	Transcriptional regulator
PSED_RS12930	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS12935	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS12955	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PSED_RS12955	COG2124	cytochrome p450
PSED_RS12960	COG2124	cytochrome p450
PSED_RS12970	COG0346	lactoylglutathione lyase activity
PSED_RS12980	COG1053	succinate dehydrogenase
PSED_RS13040	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS13055	COG3976	FMN-binding domain protein
PSED_RS13055	COG1053	succinate dehydrogenase
PSED_RS13060	COG1378	Sugar-specific transcriptional regulator TrmB
PSED_RS13065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PSED_RS13090	COG1309	transcriptional regulator
PSED_RS13105	COG2124	cytochrome p450
PSED_RS13110	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS13115	COG2814	Major facilitator Superfamily
PSED_RS13125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS13130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS13135	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
PSED_RS13140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PSED_RS13165	COG1132	(ABC) transporter
PSED_RS13175	COG0693	protein deglycase activity
PSED_RS13180	COG0183	Belongs to the thiolase family
PSED_RS13190	COG1573	uracil-dna glycosylase
PSED_RS13205	COG2326	polyphosphate kinase activity
PSED_RS13220	COG0542	response to heat
PSED_RS13320	COG0477	Major facilitator Superfamily
PSED_RS13325	COG0477	Major facilitator Superfamily
PSED_RS13370	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS13375	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS13390	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS13395	COG1024	Enoyl-CoA hydratase
PSED_RS13400	COG2072	flavoprotein involved in K transport
PSED_RS13415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PSED_RS13455	COG2271	Major facilitator Superfamily
PSED_RS13470	COG2124	cytochrome p450
PSED_RS13480	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PSED_RS13500	COG1012	belongs to the aldehyde dehydrogenase family
PSED_RS13500	COG2030	dehydratase
PSED_RS13505	COG1024	Enoyl-CoA hydratase
PSED_RS13510	COG1309	transcriptional regulator
PSED_RS13515	COG3396	Phenylacetate-CoA oxygenase
PSED_RS13520	COG3460	Phenylacetate-CoA oxygenase
PSED_RS13525	COG3396	Phenylacetate-CoA oxygenase
PSED_RS13535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PSED_RS13550	COG2017	converts alpha-aldose to the beta-anomer
PSED_RS13570	COG1309	transcriptional regulator
PSED_RS13585	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PSED_RS13600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PSED_RS13610	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PSED_RS13615	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PSED_RS13625	COG1492	cobalamin metabolic process
PSED_RS13650	COG1648	precorrin-2 dehydrogenase activity
PSED_RS13650	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PSED_RS13665	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
PSED_RS13675	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PSED_RS13675	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PSED_RS13680	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PSED_RS13685	COG1960	acyl-CoA dehydrogenase activity
PSED_RS13710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PSED_RS13745	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PSED_RS13750	COG1414	Transcriptional regulator
PSED_RS13780	COG2186	Transcriptional regulator
PSED_RS13785	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
PSED_RS13795	COG2010	Cytochrome c
PSED_RS13810	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PSED_RS13835	COG0791	NLP P60 protein
PSED_RS13840	COG0438	transferase activity, transferring glycosyl groups
PSED_RS13865	COG0003	Pfam Anion-transporting ATPase
PSED_RS13875	COG1940	carbohydrate kinase activity
PSED_RS13900	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
PSED_RS13905	COG0515	serine threonine protein kinase
PSED_RS13905	COG2815	serine threonine protein kinase
PSED_RS13930	COG0142	geranyltranstransferase activity
PSED_RS13965	COG1192	Involved in chromosome partitioning
PSED_RS13980	COG1305	Transglutaminase-like
PSED_RS13990	COG0714	Associated with various cellular activities
PSED_RS13995	COG2001	Belongs to the MraZ family
PSED_RS14000	COG0275	rRNA processing
PSED_RS14005	COG0768	penicillin binding
PSED_RS14025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PSED_RS14030	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PSED_RS14040	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PSED_RS14045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PSED_RS14060	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PSED_RS14075	COG1799	cell septum assembly
PSED_RS14075	COG1799	cell septum assembly
PSED_RS14085	COG3599	regulation of cell shape
PSED_RS14095	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PSED_RS14100	COG0586	Pfam SNARE associated Golgi protein
PSED_RS14120	COG2197	response regulator
PSED_RS14125	COG4585	Histidine kinase
PSED_RS14165	COG0297	glycogen (starch) synthase activity
PSED_RS14180	COG0477	Major facilitator Superfamily
PSED_RS14190	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PSED_RS14200	COG0156	8-amino-7-oxononanoate synthase activity
PSED_RS14205	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PSED_RS14235	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PSED_RS14245	COG0157	Belongs to the NadC ModD family
PSED_RS14250	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PSED_RS14255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PSED_RS14260	COG0131	Imidazoleglycerol-phosphate dehydratase
PSED_RS14265	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PSED_RS14275	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PSED_RS14280	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PSED_RS14285	COG0107	imidazoleglycerol-phosphate synthase activity
PSED_RS14290	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PSED_RS14305	COG4585	Histidine kinase
PSED_RS14310	COG2197	response regulator
PSED_RS14320	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PSED_RS14330	COG0134	indole-3-glycerol-phosphate synthase activity
PSED_RS14340	COG0159	tryptophan synthase activity
PSED_RS14345	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PSED_RS14360	COG1946	Acyl-CoA thioesterase
PSED_RS14370	COG2873	o-acetylhomoserine
PSED_RS14375	COG1832	CoA-binding protein
PSED_RS14385	COG0039	L-malate dehydrogenase activity
PSED_RS14415	COG3467	pyridoxamine 5'-phosphate
PSED_RS14445	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PSED_RS14450	COG0745	RESPONSE REGULATOR receiver
PSED_RS14455	COG2205	protein histidine kinase activity
PSED_RS14460	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
PSED_RS14465	COG2197	response regulator
PSED_RS14475	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PSED_RS14485	COG3253	May function as heme-dependent peroxidase
PSED_RS14490	COG0583	DNA-binding transcription factor activity
PSED_RS14500	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PSED_RS14555	COG1302	Protein conserved in bacteria
PSED_RS14565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PSED_RS14570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PSED_RS14575	COG1120	ATPase activity
PSED_RS14580	COG2326	polyphosphate kinase activity
PSED_RS14600	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PSED_RS14625	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS14630	COG1960	acyl-CoA dehydrogenase activity
PSED_RS14635	COG2030	dehydratase
PSED_RS14645	COG3001	Fructosamine kinase
PSED_RS14650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PSED_RS14680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PSED_RS14705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PSED_RS14725	COG0574	Belongs to the PEP-utilizing enzyme family
PSED_RS14725	COG3848	Pyruvate phosphate dikinase
PSED_RS14730	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PSED_RS14745	COG1960	acyl-CoA dehydrogenase activity
PSED_RS14760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS14785	COG1129	ABC transporter
PSED_RS14790	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSED_RS14825	COG0154	amidase activity
PSED_RS14865	COG2376	Dihydroxyacetone kinase
PSED_RS14870	COG1461	Dihydroxyacetone kinase
PSED_RS14880	COG0431	NADPH-dependent FMN reductase
PSED_RS14885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PSED_RS14890	COG1012	belongs to the aldehyde dehydrogenase family
PSED_RS14900	COG3243	poly(R)-hydroxyalkanoic acid synthase
PSED_RS14910	COG1490	D-aminoacyl-tRNA deacylase activity
PSED_RS14930	COG0640	Transcriptional regulator
PSED_RS14940	COG2313	pseudouridylate synthase activity
PSED_RS14965	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PSED_RS14980	COG4213	ABC transporter substrate-binding protein
PSED_RS14990	COG4214	carbohydrate transport
PSED_RS14995	COG1940	carbohydrate kinase activity
PSED_RS15035	COG2197	response regulator
PSED_RS15060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PSED_RS15065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PSED_RS15110	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSED_RS15130	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSED_RS15145	COG2186	Transcriptional regulator
PSED_RS15155	COG0154	amidase activity
PSED_RS15160	COG0439	Biotin carboxylase
PSED_RS15180	COG2814	Major facilitator Superfamily
PSED_RS15190	COG1121	(ABC) transporter
PSED_RS15195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PSED_RS15200	COG1321	iron dependent repressor
PSED_RS15215	COG3383	formate dehydrogenase (NAD+) activity
PSED_RS15285	COG0756	dUTP diphosphatase activity
PSED_RS15320	COG0569	domain protein
PSED_RS15325	COG0531	amino acid
PSED_RS15330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PSED_RS15335	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
PSED_RS15345	COG0513	Belongs to the DEAD box helicase family
PSED_RS15370	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PSED_RS15385	COG0022	dehydrogenase e1 component
PSED_RS15390	COG0508	dehydrogenase complex catalyzes the overall conversion of
PSED_RS15415	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
PSED_RS15465	COG3485	protocatechuate 3,4-dioxygenase
PSED_RS15470	COG4948	Mandelate Racemase Muconate Lactonizing
PSED_RS15475	COG4829	muconolactone delta-isomerase
PSED_RS15490	COG0196	riboflavin kinase activity
PSED_RS15500	COG2226	methyltransferase
PSED_RS15515	COG0596	Alpha beta hydrolase
PSED_RS15525	COG3180	Ammonia monooxygenase
PSED_RS15530	COG1132	(ABC) transporter
PSED_RS15600	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PSED_RS15605	COG4988	ABC transporter
PSED_RS15610	COG1294	oxidase, subunit
PSED_RS15615	COG1271	oxidase subunit
PSED_RS15655	COG2124	cytochrome p450
PSED_RS15675	COG0657	acetylesterase activity
PSED_RS15725	COG1554	hydrolase, family 65, central catalytic
PSED_RS15740	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PSED_RS15745	COG0514	ATP-dependent DNA helicase (RecQ)
PSED_RS15750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS15780	COG0028	Belongs to the TPP enzyme family
PSED_RS15810	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PSED_RS15810	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PSED_RS15835	COG1072	(Pantothenic acid kinase))
PSED_RS15875	COG0778	Nitroreductase
PSED_RS15885	COG2197	response regulator
PSED_RS15915	COG1335	isochorismatase
PSED_RS15935	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSED_RS15940	COG1129	ABC transporter
PSED_RS15960	COG0277	FAD linked oxidase domain protein
PSED_RS16005	COG0789	Transcriptional regulator
PSED_RS16015	COG4149	molybdate abc transporter
PSED_RS16020	COG3842	ATPase activity
PSED_RS16025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS16040	COG0183	Belongs to the thiolase family
PSED_RS16050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS16055	COG1024	Enoyl-CoA hydratase
PSED_RS16090	COG2072	flavoprotein involved in K transport
PSED_RS16105	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS16115	COG1309	transcriptional regulator
PSED_RS16125	COG1802	Transcriptional regulator
PSED_RS16145	COG0145	ligase activity
PSED_RS16160	COG0129	dihydroxy-acid dehydratase activity
PSED_RS16225	COG1484	DNA-dependent DNA replication
PSED_RS16230	COG4584	PFAM Integrase catalytic
PSED_RS16285	COG3189	MarR family transcriptional regulator
PSED_RS16300	COG2124	cytochrome p450
PSED_RS16305	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PSED_RS16325	COG2193	ferroxidase activity
PSED_RS16335	COG1793	dna ligase
PSED_RS16335	COG3285	dna ligase
PSED_RS16355	COG0463	Glycosyl transferase, family 2
PSED_RS16365	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PSED_RS16410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PSED_RS16440	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
PSED_RS16445	COG1597	lipid kinase activity
PSED_RS16475	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PSED_RS16490	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
PSED_RS16495	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
PSED_RS16530	COG0300	oxidoreductase activity
PSED_RS16540	COG3547	Transposase (IS116 IS110 IS902 family)
PSED_RS16570	COG1222	aaa ATPase
PSED_RS16605	COG1410	methionine synthase
PSED_RS16605	COG0646	methionine synthase
PSED_RS16615	COG2814	Major facilitator Superfamily
PSED_RS16625	COG0215	cysteine-tRNA ligase activity
PSED_RS16635	COG0738	Major facilitator superfamily
PSED_RS16650	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
PSED_RS16655	COG2318	DinB family
PSED_RS16660	COG0501	Belongs to the peptidase M48B family
PSED_RS16675	COG0477	Major facilitator Superfamily
PSED_RS16695	COG2755	lipolytic protein G-D-S-L family
PSED_RS16700	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PSED_RS16715	COG1960	acyl-CoA dehydrogenase activity
PSED_RS16720	COG1960	acyl-CoA dehydrogenase activity
PSED_RS16730	COG0310	cobalt ion transport
PSED_RS16745	COG1122	ATPase activity
PSED_RS16775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS16780	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS16785	COG0596	Alpha beta hydrolase
PSED_RS16790	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS16820	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PSED_RS16825	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PSED_RS16830	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS16835	COG2304	oxidoreductase activity
PSED_RS16845	COG0714	Associated with various cellular activities
PSED_RS16850	COG3883	PFAM NLP P60 protein
PSED_RS16850	COG0791	NLP P60 protein
PSED_RS16865	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PSED_RS16870	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PSED_RS16880	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
PSED_RS16885	COG0121	glutamine amidotransferase
PSED_RS16890	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PSED_RS16895	COG3572	ergothioneine biosynthetic process
PSED_RS16900	COG1309	transcriptional regulator
PSED_RS16920	COG0488	(ABC) transporter
PSED_RS16925	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS16930	COG0644	oxidoreductase
PSED_RS16940	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
PSED_RS16945	COG2151	metal-sulfur cluster biosynthetic enzyme
PSED_RS16950	COG0822	iron-sulfur transferase activity
PSED_RS16960	COG0396	ATPase activity
PSED_RS17005	COG0109	protoheme IX farnesyltransferase activity
PSED_RS17015	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PSED_RS17035	COG0363	glucosamine-6-phosphate deaminase activity
PSED_RS17045	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PSED_RS17065	COG0149	triose-phosphate isomerase activity
PSED_RS17070	COG0126	phosphoglycerate kinase activity
PSED_RS17080	COG1481	regulation of sporulation
PSED_RS17090	COG1660	Displays ATPase and GTPase activities
PSED_RS17095	COG0322	excinuclease ABC activity
PSED_RS17115	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PSED_RS17120	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PSED_RS17120	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PSED_RS17145	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PSED_RS17150	COG0242	peptide deformylase activity
PSED_RS17160	COG0644	oxidoreductase
PSED_RS17175	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PSED_RS17205	COG3835	regulator
PSED_RS17210	COG0783	Belongs to the Dps family
PSED_RS17250	COG0542	response to heat
PSED_RS17265	COG2326	polyphosphate kinase activity
PSED_RS17275	COG2963	transposase activity
PSED_RS17280	COG1063	alcohol dehydrogenase
PSED_RS17285	COG2823	Periplasmic or secreted lipoprotein
PSED_RS17290	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PSED_RS17310	COG4584	PFAM Integrase catalytic
PSED_RS17315	COG0582	viral genome integration into host DNA
PSED_RS17325	COG4584	PFAM Integrase catalytic
PSED_RS17330	COG1484	DNA-dependent DNA replication
PSED_RS17350	COG0028	Belongs to the TPP enzyme family
PSED_RS17390	COG0542	response to heat
PSED_RS17410	COG0443	Heat shock 70 kDa protein
PSED_RS17435	COG2271	Major facilitator Superfamily
PSED_RS17470	COG2823	Periplasmic or secreted lipoprotein
PSED_RS17485	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PSED_RS17500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSED_RS17520	COG0693	protein deglycase activity
PSED_RS17555	COG1758	RNA polymerase activity
PSED_RS17560	COG0194	GDP metabolic process
PSED_RS17575	COG0284	orotidine-5'-phosphate decarboxylase activity
PSED_RS17580	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PSED_RS17595	COG0540	Belongs to the ATCase OTCase family
PSED_RS17600	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PSED_RS17620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PSED_RS17625	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PSED_RS17630	COG0006	proline dipeptidase activity
PSED_RS17635	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PSED_RS17645	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PSED_RS17660	COG3467	pyridoxamine 5'-phosphate
PSED_RS17675	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PSED_RS17680	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PSED_RS17705	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PSED_RS17715	COG2235	arginine
PSED_RS17780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PSED_RS17785	COG1522	sequence-specific DNA binding
PSED_RS17790	COG0436	Aminotransferase
PSED_RS17810	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PSED_RS17825	COG3265	gluconokinase activity
PSED_RS17840	COG0124	histidyl-tRNA synthetase
PSED_RS17845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PSED_RS17855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PSED_RS17865	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PSED_RS17885	COG2255	four-way junction helicase activity
PSED_RS17890	COG0632	four-way junction helicase activity
PSED_RS17895	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PSED_RS17935	COG1358	cellular component organization or biogenesis
PSED_RS17970	COG0217	transcriptional regulatory protein
PSED_RS17975	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PSED_RS18010	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PSED_RS18020	COG0438	transferase activity, transferring glycosyl groups
PSED_RS18025	COG1560	Kdo2-lipid A biosynthetic process
PSED_RS18040	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PSED_RS18110	COG1741	Belongs to the pirin family
PSED_RS18120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PSED_RS18125	COG4279	zinc finger
PSED_RS18130	COG2409	Drug exporters of the RND superfamily
PSED_RS18140	COG0626	cystathionine gamma-synthase activity
PSED_RS18160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PSED_RS18180	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PSED_RS18185	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PSED_RS18245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PSED_RS18250	COG1309	transcriptional regulator
PSED_RS18295	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PSED_RS18305	COG1349	DNA-binding transcription factor activity
PSED_RS18325	COG1802	Transcriptional regulator
PSED_RS18335	COG1070	Carbohydrate kinase
PSED_RS18340	COG0235	Class ii aldolase
PSED_RS18345	COG3835	regulator
PSED_RS18350	COG1562	ergosterol biosynthetic process
PSED_RS18360	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PSED_RS18370	COG1657	PFAM Prenyltransferase squalene oxidase
PSED_RS18395	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PSED_RS18400	COG0697	spore germination
PSED_RS18405	COG4221	oxidoreductase activity
PSED_RS18410	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PSED_RS18430	COG4608	Belongs to the ABC transporter superfamily
PSED_RS18435	COG0444	Belongs to the ABC transporter superfamily
PSED_RS18440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSED_RS18465	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
PSED_RS18470	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PSED_RS18505	COG0022	dehydrogenase e1 component
PSED_RS18510	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PSED_RS18515	COG0022	dehydrogenase e1 component
PSED_RS18520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PSED_RS18530	COG0508	dehydrogenase complex catalyzes the overall conversion of
PSED_RS18540	COG1063	alcohol dehydrogenase
PSED_RS18545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PSED_RS18560	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS18565	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
PSED_RS18595	COG0683	leucine binding
PSED_RS18605	COG0022	dehydrogenase e1 component
PSED_RS18610	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PSED_RS18615	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS18670	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS18680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS18690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PSED_RS18735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PSED_RS18735	COG0596	Alpha beta hydrolase
PSED_RS18740	COG2080	2 iron, 2 sulfur cluster binding
PSED_RS18760	COG1414	Transcriptional regulator
PSED_RS18770	COG2814	Major facilitator Superfamily
PSED_RS18775	COG0069	glutamate synthase activity
PSED_RS18785	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS18790	COG2084	Dehydrogenase
PSED_RS18805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PSED_RS18830	COG0640	Transcriptional regulator
PSED_RS18840	COG4941	Belongs to the sigma-70 factor family
PSED_RS18845	COG3795	YCII-related domain
PSED_RS18860	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PSED_RS18875	COG3328	transposase activity
PSED_RS18910	COG2124	cytochrome p450
PSED_RS18915	COG1408	metallophosphoesterase
PSED_RS18955	COG2226	methyltransferase
PSED_RS18965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PSED_RS18980	COG0683	leucine binding
PSED_RS18990	COG1160	GTP binding
PSED_RS19000	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PSED_RS19015	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PSED_RS19020	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PSED_RS19045	COG0494	nUDIX hydrolase
PSED_RS19050	COG0504	CTP synthase activity
PSED_RS19070	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PSED_RS19085	COG0647	UMP catabolic process
PSED_RS19115	COG2094	Belongs to the DNA glycosylase MPG family
PSED_RS19120	COG0789	Transcriptional regulator
PSED_RS19130	COG0165	Argininosuccinate lyase
PSED_RS19135	COG0137	argininosuccinate synthase activity
PSED_RS19145	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PSED_RS19155	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PSED_RS19160	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PSED_RS19165	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PSED_RS19175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PSED_RS19175	COG0072	phenylalanine-tRNA ligase activity
PSED_RS19180	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PSED_RS19185	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PSED_RS19190	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PSED_RS19195	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PSED_RS19200	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PSED_RS19225	COG1316	TRANSCRIPTIONal
PSED_RS19240	COG0477	Major facilitator Superfamily
PSED_RS19255	COG2329	Antibiotic biosynthesis monooxygenase
PSED_RS19260	COG1131	(ABC) transporter
PSED_RS19310	COG5650	phosphatidylinositol metabolic process
PSED_RS19335	COG0237	dephospho-CoA kinase activity
PSED_RS19335	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PSED_RS19345	COG0539	negative regulation of cytoplasmic translation
PSED_RS19350	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PSED_RS19355	COG2050	protein possibly involved in aromatic compounds catabolism
PSED_RS19415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PSED_RS19420	COG1414	Transcriptional regulator
PSED_RS19425	COG3622	Belongs to the hyi family
PSED_RS19430	COG2084	Dehydrogenase
PSED_RS19435	COG3960	tartronate-semialdehyde synthase activity
PSED_RS19440	COG1929	Belongs to the glycerate kinase type-1 family
PSED_RS19445	COG2188	Transcriptional regulator
PSED_RS19465	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PSED_RS19465	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PSED_RS19475	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS19480	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS19510	COG0179	Fumarylacetoacetate (FAA) hydrolase
PSED_RS19525	COG0583	DNA-binding transcription factor activity
PSED_RS19530	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
PSED_RS19605	COG1063	alcohol dehydrogenase
PSED_RS19640	COG1522	sequence-specific DNA binding
PSED_RS19660	COG1802	Transcriptional regulator
PSED_RS19695	COG0419	ATPase involved in DNA repair
PSED_RS19700	COG0420	3'-5' exonuclease activity
PSED_RS19720	COG3655	Transcriptional regulator
PSED_RS19725	COG4974	Belongs to the 'phage' integrase family
PSED_RS19745	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PSED_RS19750	COG2358	TRAP transporter, solute receptor (TAXI family
PSED_RS19755	COG4941	Belongs to the sigma-70 factor family
PSED_RS19775	COG0642	Histidine kinase
PSED_RS19780	COG0745	RESPONSE REGULATOR receiver
PSED_RS19785	COG1126	abc transporter atp-binding protein
PSED_RS19790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PSED_RS19795	COG0765	amino acid transport
PSED_RS19800	COG0765	amino acid transport
PSED_RS19805	COG1280	lysine exporter protein (LysE YggA)
PSED_RS19815	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
PSED_RS19825	COG0174	glutamine synthetase
PSED_RS19835	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PSED_RS19845	COG0778	Nitroreductase
PSED_RS19850	COG0557	exoribonuclease II activity
PSED_RS19865	COG0179	Fumarylacetoacetate (FAA) hydrolase
PSED_RS19875	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
PSED_RS19875	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
PSED_RS19890	COG0123	including yeast histone deacetylase and acetoin utilization protein
PSED_RS19900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PSED_RS19910	COG4942	peptidase
PSED_RS19925	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS19950	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS19970	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PSED_RS19980	COG1960	acyl-CoA dehydrogenase activity
PSED_RS19990	COG0183	Belongs to the thiolase family
PSED_RS20000	COG2814	Major facilitator Superfamily
PSED_RS20010	COG1960	acyl-CoA dehydrogenase activity
PSED_RS20020	COG1960	acyl-CoA dehydrogenase activity
PSED_RS20025	COG1960	acyl-CoA dehydrogenase activity
PSED_RS20040	COG2814	Major facilitator Superfamily
PSED_RS20060	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
PSED_RS20065	COG1074	ATP-dependent DNA helicase activity
PSED_RS20095	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PSED_RS20135	COG2186	Transcriptional regulator
PSED_RS20140	COG0247	lactate metabolic process
PSED_RS20145	COG1139	Iron-sulfur cluster binding protein
PSED_RS20200	COG2271	Major facilitator Superfamily
PSED_RS20220	COG2208	phosphoserine phosphatase activity
PSED_RS20220	COG2770	Histidine kinase
PSED_RS20235	COG0583	DNA-binding transcription factor activity
PSED_RS20265	COG0009	L-threonylcarbamoyladenylate synthase
PSED_RS20280	COG3012	SEC-C Motif Domain Protein
PSED_RS20285	COG1132	(ABC) transporter
PSED_RS20290	COG1132	(ABC) transporter
PSED_RS20295	COG2807	transmembrane transport
PSED_RS20375	COG0667	Aldo Keto reductase
PSED_RS20410	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS20420	COG4608	Belongs to the ABC transporter superfamily
PSED_RS20425	COG0444	Belongs to the ABC transporter superfamily
PSED_RS20440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSED_RS20450	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS20455	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS20460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS20470	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PSED_RS20475	COG1960	acyl-CoA dehydrogenase activity
PSED_RS20485	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS20495	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS20500	COG1902	pentaerythritol trinitrate reductase activity
PSED_RS20515	COG1414	Transcriptional regulator
PSED_RS20525	COG2079	MmgE PrpD family protein
PSED_RS20560	COG4941	Belongs to the sigma-70 factor family
PSED_RS20585	COG1620	l-lactate permease
PSED_RS20595	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PSED_RS20595	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PSED_RS20600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PSED_RS20605	COG1063	alcohol dehydrogenase
PSED_RS20610	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS20625	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS20660	COG1063	alcohol dehydrogenase
PSED_RS20665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS20690	COG0456	acetyltransferase
PSED_RS20700	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
PSED_RS20705	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
PSED_RS20710	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
PSED_RS20720	COG0473	3-isopropylmalate dehydrogenase activity
PSED_RS20730	COG0154	amidase activity
PSED_RS20735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS20740	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PSED_RS20745	COG1335	isochorismatase
PSED_RS20750	COG0604	alcohol dehydrogenase
PSED_RS20760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PSED_RS20765	COG0667	Aldo Keto reductase
PSED_RS20775	COG1172	Belongs to the binding-protein-dependent transport system permease family
PSED_RS20780	COG1129	ABC transporter
PSED_RS20795	COG2186	Transcriptional regulator
PSED_RS20815	COG0129	dihydroxy-acid dehydratase activity
PSED_RS20835	COG1335	isochorismatase
PSED_RS20840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS20850	COG1802	Transcriptional regulator
PSED_RS20855	COG1414	Transcriptional regulator
PSED_RS20885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PSED_RS20890	COG1902	pentaerythritol trinitrate reductase activity
PSED_RS20895	COG1414	Transcriptional regulator
PSED_RS20900	COG1902	pentaerythritol trinitrate reductase activity
PSED_RS20900	COG0446	pyridine nucleotide-disulphide oxidoreductase
PSED_RS20905	COG4106	trans-aconitate 2-methyltransferase activity
PSED_RS20930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PSED_RS20935	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS20945	COG2267	carboxylic ester hydrolase activity
PSED_RS20950	COG1764	response to oxidative stress
PSED_RS20960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS21020	COG3467	pyridoxamine 5'-phosphate
PSED_RS21035	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PSED_RS21065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PSED_RS21080	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS21085	COG0477	Major facilitator Superfamily
PSED_RS21100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS21115	COG0243	molybdopterin cofactor binding
PSED_RS21130	COG0300	oxidoreductase activity
PSED_RS21135	COG2770	Histidine kinase
PSED_RS21135	COG2208	phosphoserine phosphatase activity
PSED_RS21155	COG1192	Involved in chromosome partitioning
PSED_RS21220	COG0179	Fumarylacetoacetate (FAA) hydrolase
PSED_RS21225	COG3473	Maleate cis-trans isomerase
PSED_RS21265	COG0628	permease
PSED_RS21270	COG1597	lipid kinase activity
PSED_RS21290	COG2326	polyphosphate kinase activity
PSED_RS21380	COG0492	ferredoxin-NADP+ reductase activity
PSED_RS21385	COG1355	regulation of microtubule-based process
PSED_RS21390	COG3971	2-oxopent-4-enoate hydratase activity
PSED_RS21395	COG1414	Transcriptional regulator
PSED_RS21410	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
PSED_RS21430	COG3971	2-oxopent-4-enoate hydratase activity
PSED_RS21470	COG1140	nitrate reductase beta subunit
PSED_RS21525	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PSED_RS21530	COG1309	transcriptional regulator
PSED_RS21570	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS21580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PSED_RS21600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PSED_RS21600	COG1017	nitric oxide dioxygenase activity
PSED_RS21615	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
PSED_RS21705	COG0640	Transcriptional regulator
PSED_RS21755	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PSED_RS21785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PSED_RS21795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
PSED_RS21795	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PSED_RS21810	COG0739	heme binding
PSED_RS21855	COG1914	H( )-stimulated, divalent metal cation uptake system
PSED_RS21935	COG2188	Transcriptional regulator
PSED_RS21940	COG0582	viral genome integration into host DNA
PSED_RS21970	COG5564	TIM-barrel signal transduction protein
PSED_RS21975	COG5441	Belongs to the UPF0261 family
PSED_RS21990	COG1940	carbohydrate kinase activity
PSED_RS22010	COG0477	Major facilitator Superfamily
PSED_RS22025	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PSED_RS22025	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PSED_RS22025	COG1703	isobutyryl-CoA mutase activity
PSED_RS22035	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PSED_RS22040	COG2814	Major facilitator Superfamily
PSED_RS22045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PSED_RS22065	COG0738	Major facilitator superfamily
PSED_RS22105	COG2226	methyltransferase
PSED_RS22125	COG0477	Major facilitator Superfamily
PSED_RS22140	COG0667	Aldo Keto reductase
PSED_RS22160	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PSED_RS22165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PSED_RS22200	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
PSED_RS22205	COG1309	transcriptional regulator
PSED_RS22220	COG4106	trans-aconitate 2-methyltransferase activity
PSED_RS22230	COG0358	DNA primase activity
PSED_RS22250	COG1595	DNA-templated transcription, initiation
PSED_RS22265	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PSED_RS22275	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PSED_RS22275	COG3608	succinylglutamate desuccinylase aspartoacylase
PSED_RS22290	COG2197	response regulator
PSED_RS22295	COG4585	Histidine kinase
PSED_RS22305	COG1131	(ABC) transporter
PSED_RS22310	COG1253	flavin adenine dinucleotide binding
PSED_RS22315	COG1253	flavin adenine dinucleotide binding
PSED_RS22320	COG0423	glycine-tRNA ligase activity
PSED_RS22355	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PSED_RS22375	COG1381	Involved in DNA repair and RecF pathway recombination
PSED_RS22390	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PSED_RS22395	COG0579	oxidoreductase
PSED_RS22410	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PSED_RS22425	COG0028	Belongs to the TPP enzyme family
PSED_RS22430	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
PSED_RS22445	COG0484	heat shock protein binding
PSED_RS22450	COG1420	regulation of RNA biosynthetic process
PSED_RS22490	COG0577	efflux transmembrane transporter activity
PSED_RS22490	COG1136	(ABC) transporter
PSED_RS22495	COG0577	efflux transmembrane transporter activity
PSED_RS22495	COG1136	(ABC) transporter
PSED_RS22535	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PSED_RS22550	COG1132	(ABC) transporter
PSED_RS22560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS22575	COG2050	protein possibly involved in aromatic compounds catabolism
PSED_RS22600	COG4290	ribonuclease
PSED_RS22610	COG0604	alcohol dehydrogenase
PSED_RS22620	COG0481	GTPase activity
PSED_RS22645	COG3103	Sh3 type 3 domain protein
PSED_RS22645	COG0791	NLP P60 protein
PSED_RS22645	COG1388	LysM domain
PSED_RS22650	COG2197	response regulator
PSED_RS22655	COG4585	Histidine kinase
PSED_RS22670	COG1024	Enoyl-CoA hydratase
PSED_RS22675	COG4122	O-methyltransferase activity
PSED_RS22690	COG1960	acyl-CoA dehydrogenase activity
PSED_RS22695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PSED_RS22705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
PSED_RS22725	COG1597	lipid kinase activity
PSED_RS22730	COG0277	FAD linked oxidase domain protein
PSED_RS22745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PSED_RS22775	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PSED_RS22780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PSED_RS22800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PSED_RS22805	COG0508	dehydrogenase complex catalyzes the overall conversion of
PSED_RS22815	COG0321	lipoyl(octanoyl) transferase activity
PSED_RS22830	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PSED_RS22845	COG0174	glutamine synthetase
PSED_RS22870	COG3548	integral membrane protein
PSED_RS22880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PSED_RS22880	COG0574	Belongs to the PEP-utilizing enzyme family
PSED_RS22885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PSED_RS22935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
PSED_RS22940	COG1053	succinate dehydrogenase
PSED_RS22955	COG2137	regulation of response to DNA damage stimulus
PSED_RS22980	COG1201	RNA secondary structure unwinding
PSED_RS22990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PSED_RS23000	COG0305	Participates in initiation and elongation during chromosome replication
PSED_RS23020	COG0706	membrane insertase activity
PSED_RS23030	COG2197	response regulator
PSED_RS23050	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PSED_RS23055	COG1842	Phage shock protein A
PSED_RS23060	COG1396	sequence-specific DNA binding
PSED_RS23070	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PSED_RS23075	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
PSED_RS23085	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
PSED_RS23090	COG2353	YceI-like domain
PSED_RS23150	COG1335	isochorismatase
PSED_RS23160	COG0154	amidase activity
PSED_RS23165	COG0154	amidase activity
PSED_RS23180	COG0747	negative chemotaxis
PSED_RS23185	COG4608	Belongs to the ABC transporter superfamily
PSED_RS23195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSED_RS23200	COG0601	transmembrane transport
PSED_RS23210	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PSED_RS23215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PSED_RS23225	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
PSED_RS23240	COG3214	Protein conserved in bacteria
PSED_RS23245	COG0697	spore germination
PSED_RS23255	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PSED_RS23270	COG1185	polyribonucleotide nucleotidyltransferase activity
PSED_RS23290	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PSED_RS23300	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PSED_RS23305	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PSED_RS23310	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PSED_RS23325	COG0195	Participates in both transcription termination and antitermination
PSED_RS23330	COG0779	Required for maturation of 30S ribosomal subunits
PSED_RS23350	COG0432	Pfam Uncharacterised protein family UPF0047
PSED_RS23360	COG0442	prolyl-tRNA aminoacylation
PSED_RS23365	COG1278	Cold shock
PSED_RS23375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PSED_RS23385	COG3022	response to hydroperoxide
PSED_RS23400	COG0513	Belongs to the DEAD box helicase family
PSED_RS23405	COG0215	cysteine-tRNA ligase activity
PSED_RS23450	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PSED_RS23455	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
PSED_RS23495	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PSED_RS23510	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
PSED_RS23520	COG3285	dna ligase
PSED_RS23520	COG1793	dna ligase
PSED_RS23535	COG3663	DNA glycosylase
PSED_RS23540	COG1793	dna ligase
PSED_RS23545	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PSED_RS23560	COG0723	plastoquinol--plastocyanin reductase activity
PSED_RS23580	COG0528	UMP kinase activity
PSED_RS23590	COG0052	Belongs to the universal ribosomal protein uS2 family
PSED_RS23600	COG1191	sigma factor activity
PSED_RS23620	COG0792	nuclease activity
PSED_RS23630	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PSED_RS23640	COG0335	large ribosomal subunit rRNA binding
PSED_RS23645	COG0336	Belongs to the RNA methyltransferase TrmD family
PSED_RS23650	COG1285	pathogenesis
PSED_RS23655	COG0542	response to heat
PSED_RS23665	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PSED_RS23675	COG0228	four-way junction DNA binding
PSED_RS23710	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
PSED_RS23745	COG2340	Cysteine-rich secretory protein family
PSED_RS23755	COG0598	Magnesium transport protein CorA
PSED_RS23760	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PSED_RS23765	COG0571	ribonuclease III activity
PSED_RS23770	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PSED_RS23785	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PSED_RS23790	COG0742	ribosomal rna small subunit methyltransferase
PSED_RS23805	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PSED_RS23810	COG1461	Dihydroxyacetone kinase
PSED_RS23815	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PSED_RS23820	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PSED_RS23830	COG1320	monovalent cation:proton antiporter activity
PSED_RS23835	COG2212	antiporter activity
PSED_RS23840	COG1863	multisubunit Na H antiporter MnhE subunit
PSED_RS23845	COG0651	ATP synthesis coupled electron transport
PSED_RS23850	COG1006	Multisubunit Na H antiporter MnhC subunit
PSED_RS23855	COG2111	Na H antiporter
PSED_RS23860	COG2111	Na H antiporter
PSED_RS23860	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PSED_RS23865	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
PSED_RS23870	COG0277	FAD linked oxidase domain protein
PSED_RS23875	COG0277	FAD linked oxidase domain protein
PSED_RS23880	COG0247	lactate metabolic process
PSED_RS23895	COG0277	FAD linked oxidase domain protein
PSED_RS23900	COG0277	FAD linked oxidase domain protein
PSED_RS23905	COG0247	lactate metabolic process
PSED_RS23925	COG1181	Belongs to the D-alanine--D-alanine ligase family
PSED_RS23930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PSED_RS23950	COG1505	serine-type exopeptidase activity
PSED_RS23955	COG0668	transmembrane transport
PSED_RS23965	COG0366	Alpha amylase catalytic
PSED_RS23980	COG2902	Dehydrogenase
PSED_RS23995	COG0629	single-stranded DNA binding
PSED_RS24060	COG1131	(ABC) transporter
PSED_RS24090	COG2205	protein histidine kinase activity
PSED_RS24100	COG0586	Pfam SNARE associated Golgi protein
PSED_RS24120	COG0642	Histidine kinase
PSED_RS24130	COG2837	iron assimilation
PSED_RS24140	COG0672	)-iron permease
PSED_RS24165	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PSED_RS24235	COG2826	transposase and inactivated derivatives, IS30 family
PSED_RS24240	COG4974	Belongs to the 'phage' integrase family
PSED_RS24245	COG3655	Transcriptional regulator
PSED_RS24290	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PSED_RS24295	COG0586	Pfam SNARE associated Golgi protein
PSED_RS24315	COG0772	Belongs to the SEDS family
PSED_RS24370	COG1331	Highly conserved protein containing a thioredoxin domain
PSED_RS24475	COG1024	Enoyl-CoA hydratase
PSED_RS24490	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS24505	COG4106	trans-aconitate 2-methyltransferase activity
PSED_RS24515	COG2186	Transcriptional regulator
PSED_RS24520	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PSED_RS24525	COG2218	PFAM glutamate synthase alpha subunit domain protein
PSED_RS24530	COG0069	glutamate synthase activity
PSED_RS24540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PSED_RS24550	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PSED_RS24550	COG0446	pyridine nucleotide-disulphide oxidoreductase
PSED_RS24565	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PSED_RS24570	COG0183	Belongs to the thiolase family
PSED_RS24590	COG0765	amino acid transport
PSED_RS24595	COG1126	abc transporter atp-binding protein
PSED_RS24620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS24630	COG1846	Transcriptional regulator
PSED_RS24650	COG1024	Enoyl-CoA hydratase
PSED_RS24655	COG1309	transcriptional regulator
PSED_RS24685	COG3622	Belongs to the hyi family
PSED_RS24695	COG0277	FAD linked oxidase domain protein
PSED_RS24695	COG0247	lactate metabolic process
PSED_RS24770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS24775	COG3485	protocatechuate 3,4-dioxygenase
PSED_RS24795	COG0022	dehydrogenase e1 component
PSED_RS24800	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PSED_RS24805	COG1959	2 iron, 2 sulfur cluster binding
PSED_RS24830	COG1024	Enoyl-CoA hydratase
PSED_RS24835	COG3585	molybdate ion transport
PSED_RS24855	COG0667	Aldo Keto reductase
PSED_RS24895	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS24895	COG0604	alcohol dehydrogenase
PSED_RS24895	COG3321	synthase
PSED_RS24905	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PSED_RS24910	COG0633	Ferredoxin
PSED_RS24910	COG0543	2 iron, 2 sulfur cluster binding
PSED_RS24920	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PSED_RS24925	COG1573	uracil-dna glycosylase
PSED_RS24950	COG0783	Belongs to the Dps family
PSED_RS24955	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PSED_RS24975	COG4221	oxidoreductase activity
PSED_RS24985	COG0583	DNA-binding transcription factor activity
PSED_RS24990	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
PSED_RS25000	COG0657	acetylesterase activity
PSED_RS25005	COG0523	cobalamin synthesis protein
PSED_RS25030	COG1796	DNA polymerase
PSED_RS25030	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
PSED_RS25040	COG0277	FAD linked oxidase domain protein
PSED_RS25050	COG4948	Mandelate Racemase Muconate Lactonizing
PSED_RS25070	COG0745	RESPONSE REGULATOR receiver
PSED_RS25075	COG2205	protein histidine kinase activity
PSED_RS25080	COG1968	undecaprenyl-diphosphatase activity
PSED_RS25085	COG1316	TRANSCRIPTIONal
PSED_RS25100	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PSED_RS25135	COG0433	COG0433 Predicted ATPase
PSED_RS25140	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
PSED_RS25155	COG0163	prenyltransferase activity
PSED_RS25160	COG1335	isochorismatase
PSED_RS25180	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
PSED_RS25185	COG1802	Transcriptional regulator
PSED_RS25205	COG0596	Alpha beta hydrolase
PSED_RS25245	COG0596	Alpha beta hydrolase
PSED_RS25250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PSED_RS25275	COG0179	Fumarylacetoacetate (FAA) hydrolase
PSED_RS25295	COG2133	pyrroloquinoline quinone binding
PSED_RS25305	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PSED_RS25320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PSED_RS25325	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PSED_RS25335	COG3483	tryptophan 2,3-dioxygenase activity
PSED_RS25360	COG2814	Major facilitator Superfamily
PSED_RS25365	COG2382	esterase
PSED_RS25370	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PSED_RS25395	COG1968	undecaprenyl-diphosphatase activity
PSED_RS25400	COG0667	Aldo Keto reductase
PSED_RS25420	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS25425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PSED_RS25470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS25480	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PSED_RS25500	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS25510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS25520	COG0567	Dehydrogenase, E1 component
PSED_RS25520	COG0508	dehydrogenase complex catalyzes the overall conversion of
PSED_RS25530	COG1674	ftsk spoiiie
PSED_RS25550	COG2132	Multicopper oxidase
PSED_RS25575	COG3284	Transcriptional regulator
PSED_RS25575	COG3284	Transcriptional regulator
PSED_RS25580	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS25600	COG1174	glycine betaine transport
PSED_RS25610	COG5001	Diguanylate cyclase
PSED_RS25610	COG3300	MHYT domain
PSED_RS25620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PSED_RS25640	COG0745	RESPONSE REGULATOR receiver
PSED_RS25645	COG5002	protein histidine kinase activity
PSED_RS25670	COG0500	methyltransferase
PSED_RS25675	COG0406	alpha-ribazole phosphatase activity
PSED_RS25695	COG1597	lipid kinase activity
PSED_RS25710	COG5662	AntiSigma factor
PSED_RS25720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PSED_RS25735	COG2135	peptidase activity
PSED_RS25740	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PSED_RS25745	COG1162	GTPase activity
PSED_RS25770	COG1012	belongs to the aldehyde dehydrogenase family
PSED_RS25780	COG1024	Enoyl-CoA hydratase
PSED_RS25800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PSED_RS25830	COG0653	protein targeting
PSED_RS25835	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PSED_RS25840	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PSED_RS25845	COG5401	PFAM Sporulation and spore germination
PSED_RS25850	COG5002	protein histidine kinase activity
PSED_RS25855	COG0745	RESPONSE REGULATOR receiver
PSED_RS25870	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PSED_RS25880	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS25900	COG0531	amino acid
PSED_RS25905	COG0686	Belongs to the AlaDH PNT family
PSED_RS25910	COG1522	sequence-specific DNA binding
PSED_RS25920	COG1482	cell wall glycoprotein biosynthetic process
PSED_RS25930	COG2835	tetraacyldisaccharide 4'-kinase activity
PSED_RS25935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PSED_RS25960	COG1994	Peptidase M50
PSED_RS25970	COG0778	Nitroreductase
PSED_RS25970	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
PSED_RS25980	COG0386	Belongs to the glutathione peroxidase family
PSED_RS25990	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
PSED_RS26010	COG1316	TRANSCRIPTIONal
PSED_RS26030	COG0628	permease
PSED_RS26060	COG1674	ftsk spoiiie
PSED_RS26095	COG0582	viral genome integration into host DNA
PSED_RS26115	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PSED_RS26130	COG2205	protein histidine kinase activity
PSED_RS26135	COG0745	RESPONSE REGULATOR receiver
PSED_RS26140	COG0483	inositol monophosphate 1-phosphatase activity
PSED_RS26165	COG0778	Nitroreductase
PSED_RS26170	COG1064	alcohol dehydrogenase
PSED_RS26185	COG1959	2 iron, 2 sulfur cluster binding
PSED_RS26190	COG1960	acyl-CoA dehydrogenase activity
PSED_RS26200	COG1960	acyl-CoA dehydrogenase activity
PSED_RS26220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PSED_RS26230	COG0424	maF-like protein
PSED_RS26250	COG3220	belongs to the UPF0276 family
PSED_RS26255	COG3220	belongs to the UPF0276 family
PSED_RS26260	COG4770	biotin carboxylase activity
PSED_RS26290	COG4770	biotin carboxylase activity
PSED_RS26295	COG2301	Belongs to the HpcH HpaI aldolase family
PSED_RS26300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PSED_RS26305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PSED_RS26310	COG1024	Enoyl-CoA hydratase
PSED_RS26325	COG0477	Major facilitator Superfamily
PSED_RS26340	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
PSED_RS26340	COG1473	amidohydrolase
PSED_RS26355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PSED_RS26375	COG0596	Alpha beta hydrolase
PSED_RS26395	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PSED_RS26415	COG1686	Belongs to the peptidase S11 family
PSED_RS26420	COG1295	ribonuclease BN
PSED_RS26425	COG0180	Tryptophanyl-tRNA synthetase
PSED_RS26435	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS26450	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
PSED_RS26460	COG0515	serine threonine protein kinase
PSED_RS26485	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PSED_RS26500	COG0587	DNA-directed DNA polymerase activity
PSED_RS26505	COG0477	Major facilitator Superfamily
PSED_RS26515	COG0492	ferredoxin-NADP+ reductase activity
PSED_RS26515	COG3118	belongs to the thioredoxin family
PSED_RS26520	COG0789	Transcriptional regulator
PSED_RS26575	COG0045	succinate-CoA ligase (ADP-forming) activity
PSED_RS26580	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
PSED_RS26585	COG4942	peptidase
PSED_RS26645	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PSED_RS26645	COG0519	Catalyzes the synthesis of GMP from XMP
PSED_RS26655	COG3654	unkown
PSED_RS26665	COG0516	GMP reductase activity
PSED_RS26695	COG2197	response regulator
PSED_RS26715	COG0459	protein refolding
PSED_RS26720	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PSED_RS26730	COG0667	Aldo Keto reductase
PSED_RS26735	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PSED_RS26740	COG0456	acetyltransferase
PSED_RS26765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PSED_RS26795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PSED_RS26800	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PSED_RS26805	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PSED_RS26820	COG0456	acetyltransferase
PSED_RS26835	COG1228	amidohydrolase
PSED_RS26855	COG1674	ftsk spoiiie
PSED_RS26865	COG1404	Belongs to the peptidase S8 family
PSED_RS26875	COG2197	response regulator
PSED_RS26880	COG4585	Histidine kinase
PSED_RS26890	COG0101	tRNA pseudouridine synthase activity
PSED_RS26895	COG0203	ribosomal protein L17
PSED_RS26900	COG0202	RNA polymerase activity
PSED_RS26905	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PSED_RS26910	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PSED_RS26920	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PSED_RS26925	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PSED_RS26940	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
PSED_RS26955	COG0563	adenylate kinase activity
PSED_RS26965	COG0200	Binds to the 23S rRNA
PSED_RS26970	COG1841	ribosomal large subunit assembly
PSED_RS26975	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PSED_RS26980	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PSED_RS26985	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PSED_RS26990	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PSED_RS26995	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PSED_RS27000	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PSED_RS27010	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PSED_RS27025	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PSED_RS27035	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PSED_RS27040	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PSED_RS27045	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PSED_RS27050	COG0089	rRNA binding
PSED_RS27055	COG0088	Forms part of the polypeptide exit tunnel
PSED_RS27060	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PSED_RS27065	COG0051	transcription antitermination factor activity, RNA binding
PSED_RS27070	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PSED_RS27075	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PSED_RS27080	COG0049	tRNA binding
PSED_RS27085	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PSED_RS27090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PSED_RS27095	COG0085	RNA polymerase activity
PSED_RS27100	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS27105	COG0222	ribosome binding
PSED_RS27130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
PSED_RS27155	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PSED_RS27175	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PSED_RS27190	COG2205	protein histidine kinase activity
PSED_RS27195	COG2197	response regulator
PSED_RS27215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PSED_RS27220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS27225	COG0081	regulation of translation
PSED_RS27240	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
PSED_RS27250	COG0436	Aminotransferase
PSED_RS27265	COG2030	dehydratase
PSED_RS27270	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PSED_RS27295	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
PSED_RS27295	COG1672	PFAM Archaeal ATPase
PSED_RS27305	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS27320	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PSED_RS27325	COG1950	PFAM Membrane protein of
PSED_RS27335	COG2076	Multidrug Resistance protein
PSED_RS27340	COG4667	esterase of the alpha-beta hydrolase superfamily
PSED_RS27345	COG2826	transposase and inactivated derivatives, IS30 family
PSED_RS27395	COG2890	protein-(glutamine-N5) methyltransferase activity
PSED_RS27420	COG1960	acyl-CoA dehydrogenase activity
PSED_RS27435	COG0183	Belongs to the thiolase family
PSED_RS27460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS27470	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS27490	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS27505	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PSED_RS27590	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PSED_RS27600	COG1666	GTP binding
PSED_RS27655	COG0501	Belongs to the peptidase M48B family
PSED_RS27670	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
PSED_RS27670	COG0674	pyruvate-flavodoxin oxidoreductase activity
PSED_RS27675	COG1013	pyruvate-flavodoxin oxidoreductase activity
PSED_RS27700	COG0142	geranyltranstransferase activity
PSED_RS27705	COG1007	ATP synthesis coupled electron transport
PSED_RS27720	COG0713	ATP synthesis coupled electron transport
PSED_RS27730	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSED_RS27735	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
PSED_RS27740	COG1034	ATP synthesis coupled electron transport
PSED_RS27755	COG0649	NAD binding
PSED_RS27760	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSED_RS27765	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
PSED_RS27775	COG0644	oxidoreductase
PSED_RS27780	COG2226	methyltransferase
PSED_RS27785	COG0438	transferase activity, transferring glycosyl groups
PSED_RS27795	COG0483	inositol monophosphate 1-phosphatase activity
PSED_RS27815	COG1169	isochorismate synthase
PSED_RS27850	COG1017	nitric oxide dioxygenase activity
PSED_RS27850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PSED_RS27865	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PSED_RS27870	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PSED_RS27875	COG0488	(ABC) transporter
PSED_RS27895	COG0277	FAD linked oxidase domain protein
PSED_RS27905	COG0454	-acetyltransferase
PSED_RS27905	COG0456	acetyltransferase
PSED_RS27925	COG1643	Atp-dependent helicase
PSED_RS27965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PSED_RS27975	COG4232	protein-disulfide reductase activity
PSED_RS27985	COG0406	alpha-ribazole phosphatase activity
PSED_RS27990	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PSED_RS28015	COG0113	porphobilinogen synthase activity
PSED_RS28020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PSED_RS28020	COG1648	precorrin-2 dehydrogenase activity
PSED_RS28025	COG0181	hydroxymethylbilane synthase activity
PSED_RS28030	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PSED_RS28035	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PSED_RS28055	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS28090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PSED_RS28105	COG1082	Xylose isomerase domain protein TIM barrel
PSED_RS28125	COG5002	protein histidine kinase activity
PSED_RS28130	COG0588	phosphoglycerate mutase activity
PSED_RS28155	COG0438	transferase activity, transferring glycosyl groups
PSED_RS28175	COG2814	Major facilitator Superfamily
PSED_RS28185	COG1278	Cold shock
PSED_RS28190	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS28195	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PSED_RS28225	COG1960	acyl-CoA dehydrogenase activity
PSED_RS28230	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PSED_RS28240	COG3191	aminopeptidase activity
PSED_RS28255	COG0745	RESPONSE REGULATOR receiver
PSED_RS28260	COG2205	protein histidine kinase activity
PSED_RS28275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PSED_RS28330	COG0446	pyridine nucleotide-disulphide oxidoreductase
PSED_RS28330	COG1902	pentaerythritol trinitrate reductase activity
PSED_RS28340	COG0535	radical SAM domain protein
PSED_RS28360	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS28375	COG4585	Histidine kinase
PSED_RS28425	COG0351	phosphomethylpyrimidine kinase
PSED_RS28440	COG1136	(ABC) transporter
PSED_RS28445	COG3851	Histidine kinase
PSED_RS28450	COG2197	response regulator
PSED_RS28455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PSED_RS28460	COG0242	peptide deformylase activity
PSED_RS28475	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PSED_RS28480	COG1183	phosphatidylcholine synthase activity
PSED_RS28485	COG0688	phosphatidylethanolamine metabolic process
PSED_RS28495	COG1278	Cold shock
PSED_RS28500	COG0459	protein refolding
PSED_RS28535	COG1061	Type III restriction enzyme res subunit
PSED_RS28550	COG2018	Roadblock/LC7 domain
PSED_RS28585	COG1652	LysM domain
PSED_RS28590	COG0315	cyclic pyranopterin monophosphate synthase activity
PSED_RS28595	COG0521	Mo-molybdopterin cofactor biosynthetic process
PSED_RS28635	COG2022	thiamine diphosphate biosynthetic process
PSED_RS28645	COG2022	thiamine diphosphate biosynthetic process
PSED_RS28645	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PSED_RS28810	COG1674	ftsk spoiiie
PSED_RS29020	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
PSED_RS29035	COG5285	phytanoyl-CoA dioxygenase
PSED_RS29040	COG1917	Cupin 2, conserved barrel domain protein
PSED_RS29050	COG0456	acetyltransferase
PSED_RS29055	COG2072	flavoprotein involved in K transport
PSED_RS29105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS29110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS29115	COG0431	NADPH-dependent FMN reductase
PSED_RS29125	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PSED_RS29130	COG2826	transposase and inactivated derivatives, IS30 family
PSED_RS29195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PSED_RS29200	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PSED_RS29215	COG0438	transferase activity, transferring glycosyl groups
PSED_RS29225	COG3158	transport of potassium into the cell
PSED_RS29245	COG2814	Major facilitator Superfamily
PSED_RS29250	COG1063	alcohol dehydrogenase
PSED_RS29285	COG1376	ErfK ybiS ycfS ynhG family protein
PSED_RS29290	COG2070	2-Nitropropane dioxygenase
PSED_RS29320	COG5398	heme oxygenase
PSED_RS29360	COG2197	response regulator
PSED_RS29375	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PSED_RS29375	COG2124	cytochrome p450
PSED_RS29390	COG0477	Major facilitator Superfamily
PSED_RS29440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PSED_RS29465	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
PSED_RS29470	COG0145	ligase activity
PSED_RS29475	COG4647	ligase activity
PSED_RS29480	COG0145	ligase activity
PSED_RS29485	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
PSED_RS29510	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PSED_RS29530	COG3387	PFAM Glycoside hydrolase 15-related
PSED_RS29550	COG2318	DinB family
PSED_RS29570	COG1024	Enoyl-CoA hydratase
PSED_RS29600	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PSED_RS29635	COG5002	protein histidine kinase activity
PSED_RS29640	COG0745	RESPONSE REGULATOR receiver
PSED_RS29660	COG0154	amidase activity
PSED_RS29730	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
PSED_RS29735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PSED_RS29785	COG0154	amidase activity
PSED_RS29790	COG2207	Transcriptional regulator
PSED_RS29795	COG0667	Aldo Keto reductase
PSED_RS29810	COG2072	flavoprotein involved in K transport
PSED_RS29820	COG3284	Transcriptional regulator
PSED_RS29825	COG0477	Major facilitator Superfamily
PSED_RS29880	COG3284	Transcriptional regulator
PSED_RS29885	COG2902	Dehydrogenase
PSED_RS29910	COG1846	Transcriptional regulator
PSED_RS29945	COG1522	sequence-specific DNA binding
PSED_RS29950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PSED_RS29955	COG0436	Aminotransferase
PSED_RS29965	COG0601	transmembrane transport
PSED_RS29970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PSED_RS29975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PSED_RS29980	COG1228	amidohydrolase
PSED_RS29990	COG4608	Belongs to the ABC transporter superfamily
PSED_RS29995	COG0745	RESPONSE REGULATOR receiver
PSED_RS30025	COG4948	Mandelate Racemase Muconate Lactonizing
PSED_RS30030	COG0028	Belongs to the TPP enzyme family
PSED_RS30035	COG0277	FAD linked oxidase domain protein
PSED_RS30035	COG0247	lactate metabolic process
PSED_RS30040	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS30050	COG0784	Response regulator, receiver
PSED_RS30065	COG2267	carboxylic ester hydrolase activity
PSED_RS30075	COG3384	dioxygenase
PSED_RS30080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS30110	COG3655	Transcriptional regulator
PSED_RS30115	COG4974	Belongs to the 'phage' integrase family
PSED_RS30120	COG2826	transposase and inactivated derivatives, IS30 family
PSED_RS30130	COG3328	transposase activity
PSED_RS30140	COG0154	amidase activity
PSED_RS30145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PSED_RS30175	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
PSED_RS30195	COG4829	muconolactone delta-isomerase
PSED_RS30200	COG4948	Mandelate Racemase Muconate Lactonizing
PSED_RS30205	COG3485	protocatechuate 3,4-dioxygenase
PSED_RS30215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PSED_RS30220	COG1414	Transcriptional regulator
PSED_RS30260	COG4974	Belongs to the 'phage' integrase family
PSED_RS30270	COG3328	transposase activity
PSED_RS30280	COG3328	transposase activity
PSED_RS30340	COG1609	Transcriptional regulator
PSED_RS30345	COG0803	Belongs to the bacterial solute-binding protein 9 family
PSED_RS30350	COG3842	ATPase activity
PSED_RS30355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PSED_RS30365	COG0215	cysteine-tRNA ligase activity
PSED_RS30375	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
PSED_RS30395	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PSED_RS30430	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PSED_RS30455	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PSED_RS30460	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PSED_RS30465	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PSED_RS30470	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PSED_RS30495	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PSED_RS30500	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PSED_RS30505	COG0302	gtp cyclohydrolase
PSED_RS30510	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PSED_RS30520	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PSED_RS30525	COG0037	tRNA processing
PSED_RS30535	COG2027	D-alanyl-D-alanine carboxypeptidase
PSED_RS30540	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PSED_RS30545	COG0179	Fumarylacetoacetate (FAA) hydrolase
PSED_RS30605	COG2267	carboxylic ester hydrolase activity
PSED_RS30615	COG0183	Belongs to the thiolase family
PSED_RS30635	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PSED_RS30645	COG1960	acyl-CoA dehydrogenase activity
PSED_RS30655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PSED_RS30665	COG1309	transcriptional regulator
PSED_RS30670	COG2217	Heavy metal translocating P-type atpase
PSED_RS30685	COG0640	Transcriptional regulator
PSED_RS30690	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PSED_RS30695	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
PSED_RS30700	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PSED_RS30705	COG1984	allophanate hydrolase subunit 2
PSED_RS30710	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PSED_RS30730	COG2030	dehydratase
PSED_RS30735	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS30740	COG0183	Belongs to the thiolase family
PSED_RS30755	COG1063	alcohol dehydrogenase
PSED_RS30790	COG2814	Major facilitator Superfamily
PSED_RS30820	COG2364	Membrane
PSED_RS30825	COG1132	(ABC) transporter
PSED_RS30845	COG0477	Major facilitator Superfamily
PSED_RS30865	COG3104	oligopeptide transport
PSED_RS30870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS30875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS30880	COG2079	MmgE PrpD family protein
PSED_RS30885	COG0154	amidase activity
PSED_RS30895	COG1960	acyl-CoA dehydrogenase activity
PSED_RS30900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
PSED_RS30905	COG2188	Transcriptional regulator
PSED_RS30930	COG1234	tRNA 3'-trailer cleavage
PSED_RS30965	COG0318	PFAM AMP-dependent synthetase and ligase
PSED_RS30970	COG1309	transcriptional regulator
PSED_RS30975	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS30995	COG2197	response regulator
PSED_RS31005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PSED_RS31010	COG0509	glycine decarboxylation via glycine cleavage system
PSED_RS31020	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PSED_RS31025	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PSED_RS31030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS31040	COG0126	phosphoglycerate kinase activity
PSED_RS31050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PSED_RS31075	COG0572	uridine kinase
PSED_RS31080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PSED_RS31085	COG2197	response regulator
PSED_RS31095	COG2826	transposase and inactivated derivatives, IS30 family
PSED_RS31100	COG3588	fructose-bisphosphate aldolase
PSED_RS31105	COG1850	ribulose-bisphosphate carboxylase activity
PSED_RS31115	COG0464	growth
PSED_RS31130	COG2197	response regulator
PSED_RS31135	COG2072	flavoprotein involved in K transport
PSED_RS31145	COG1295	ribonuclease BN
PSED_RS31160	COG1129	ABC transporter
PSED_RS31180	COG2186	Transcriptional regulator
PSED_RS31185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PSED_RS31190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PSED_RS31220	COG0697	spore germination
PSED_RS31235	COG1304	FMN binding
PSED_RS31250	COG0438	transferase activity, transferring glycosyl groups
PSED_RS31255	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PSED_RS31290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PSED_RS31295	COG1809	phosphosulfolactate synthase activity
PSED_RS31305	COG0412	Dienelactone hydrolase
PSED_RS31310	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
PSED_RS31320	COG1960	acyl-CoA dehydrogenase activity
PSED_RS31340	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS31360	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
PSED_RS31365	COG3285	dna ligase
PSED_RS31365	COG1793	dna ligase
PSED_RS31430	COG2197	response regulator
PSED_RS31455	COG3708	Transcriptional regulator
PSED_RS31455	COG2207	Transcriptional regulator
PSED_RS31465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PSED_RS31485	COG3903	Transcriptional regulator
PSED_RS31485	COG3629	intracellular signal transduction
PSED_RS31500	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
PSED_RS31510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PSED_RS31515	COG1028	Short-chain dehydrogenase reductase Sdr
PSED_RS31530	COG1024	Enoyl-CoA hydratase
PSED_RS31550	COG0145	ligase activity
PSED_RS31565	COG3473	Maleate cis-trans isomerase
PSED_RS31585	COG2826	transposase and inactivated derivatives, IS30 family
PSED_RS31610	COG2197	response regulator
PSED_RS31625	COG3012	SEC-C Motif Domain Protein
PSED_RS31635	COG3547	Transposase (IS116 IS110 IS902 family)
PSED_RS31650	COG0375	protein maturation
PSED_RS31665	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
PSED_RS31705	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
PSED_RS31710	COG0298	carbon dioxide binding
PSED_RS31720	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
PSED_RS31725	COG0309	Hydrogenase expression formation protein (HypE)
PSED_RS31730	COG0298	carbon dioxide binding
PSED_RS31735	COG0409	Hydrogenase expression formation protein
PSED_RS31765	COG3012	SEC-C Motif Domain Protein
PSED_RS31845	COG1131	(ABC) transporter
PSED_RS31850	COG2217	Heavy metal translocating P-type atpase
PSED_RS31855	COG2072	flavoprotein involved in K transport
PSED_RS31865	COG2197	response regulator
PSED_RS31870	COG1672	PFAM Archaeal ATPase
PSED_RS31870	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
PSED_RS31875	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
PSED_RS31900	COG0745	RESPONSE REGULATOR receiver
PSED_RS31905	COG2205	protein histidine kinase activity
PSED_RS31920	COG1271	oxidase subunit
PSED_RS31925	COG1294	oxidase, subunit
PSED_RS31930	COG3387	PFAM Glycoside hydrolase 15-related
PSED_RS31935	COG1252	NADH dehydrogenase
PSED_RS31960	COG1278	Cold shock
PSED_RS31975	COG0531	amino acid
PSED_RS31995	COG0745	RESPONSE REGULATOR receiver
PSED_RS32000	COG0489	protein tyrosine kinase activity
PSED_RS32015	COG0277	FAD linked oxidase domain protein
PSED_RS32020	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
PSED_RS32020	COG1672	PFAM Archaeal ATPase
PSED_RS32055	COG0477	Major facilitator Superfamily
PSED_RS32065	COG0596	Alpha beta hydrolase
PSED_RS32105	COG1309	transcriptional regulator
PSED_RS32120	COG2186	Transcriptional regulator
PSED_RS32130	COG2271	Major facilitator Superfamily
PSED_RS32135	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PSED_RS32165	COG2508	Transcriptional regulator
PSED_RS32185	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
PSED_RS32195	COG1529	Aldehyde oxidase and xanthine dehydrogenase
PSED_RS32225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS32280	COG0470	DNA polymerase III
PSED_RS32285	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PSED_RS32405	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PSED_RS32415	COG0831	urea catabolic process
PSED_RS32420	COG0832	Belongs to the urease beta subunit family
PSED_RS32425	COG0804	urea catabolic process
PSED_RS32435	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PSED_RS32440	COG0829	nickel cation binding
PSED_RS32475	COG0586	Pfam SNARE associated Golgi protein
PSED_RS32490	COG1414	Transcriptional regulator
PSED_RS32525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PSED_RS32530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PSED_RS32545	COG0300	oxidoreductase activity
PSED_RS32575	COG0542	response to heat
PSED_RS32580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PSED_RS32600	COG0789	Transcriptional regulator
PSED_RS32605	COG0484	heat shock protein binding
PSED_RS32610	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PSED_RS32615	COG0443	Heat shock 70 kDa protein
PSED_RS32670	COG0247	lactate metabolic process
PSED_RS32670	COG2181	nitrate reductase activity
PSED_RS32680	COG2197	response regulator
PSED_RS32700	COG0717	Belongs to the dCTP deaminase family
PSED_RS32730	COG1660	Displays ATPase and GTPase activities
PSED_RS32785	COG1652	LysM domain
PSED_RS32830	COG2080	2 iron, 2 sulfur cluster binding
PSED_RS32850	COG1960	acyl-CoA dehydrogenase activity
PSED_RS32855	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PSED_RS32855	COG0517	IMP dehydrogenase activity
PSED_RS32860	COG2720	vancomycin resistance protein
PSED_RS32890	COG0508	dehydrogenase complex catalyzes the overall conversion of
PSED_RS32895	COG0022	dehydrogenase e1 component
PSED_RS32915	COG0765	amino acid transport
PSED_RS32920	COG1126	abc transporter atp-binding protein
PSED_RS32945	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
PSED_RS32970	COG0477	Major facilitator Superfamily
PSED_RS32985	COG1309	transcriptional regulator
PSED_RS33025	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PSED_RS33030	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
PSED_RS33060	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
PSED_RS33070	COG0402	S-adenosylhomocysteine deaminase activity
PSED_RS33090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
PSED_RS33095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PSED_RS33105	COG0305	Participates in initiation and elongation during chromosome replication
PSED_RS33110	COG0359	binds to the 23S rRNA
PSED_RS33115	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PSED_RS33155	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PSED_RS33175	COG0791	NLP P60 protein
PSED_RS33190	COG0495	leucyl-tRNA aminoacylation
PSED_RS33200	COG1678	Uncharacterized ACR, COG1678
PSED_RS33210	COG0617	tRNA 3'-terminal CCA addition
PSED_RS33230	COG1595	DNA-templated transcription, initiation
PSED_RS33250	COG3409	Peptidoglycan-binding domain 1 protein
PSED_RS33250	COG0860	N-Acetylmuramoyl-L-alanine amidase
PSED_RS33260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PSED_RS33265	COG1181	Belongs to the D-alanine--D-alanine ligase family
PSED_RS33275	COG1192	Involved in chromosome partitioning
PSED_RS33280	COG0357	Ribosomal RNA small subunit methyltransferase G
PSED_RS33290	COG0706	membrane insertase activity
PSED_RS33295	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PSED_RS33300	COG0594	ribonuclease P activity
PSED_RS34090	COG2814	Major facilitator Superfamily
PSED_RS34210	COG0754	glutathionylspermidine amidase activity
PSED_RS34220	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
PSED_RS34270	COG0187	DNA topoisomerase II activity
PSED_RS34325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
PSED_RS34415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS34465	COG5280	Phage tail tape measure protein TP901
PSED_RS34465	COG3953	SLT domain
PSED_RS34510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PSED_RS34535	COG2119	membrane
PSED_RS34540	COG1316	TRANSCRIPTIONal
PSED_RS34590	COG2205	protein histidine kinase activity
PSED_RS34600	COG0438	transferase activity, transferring glycosyl groups
PSED_RS34620	COG0477	Major facilitator Superfamily
PSED_RS34635	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PSED_RS34640	COG0671	phosphoesterase, PA-phosphatase related
PSED_RS34695	COG1802	Transcriptional regulator
PSED_RS34700	COG1082	Xylose isomerase domain protein TIM barrel
PSED_RS34700	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PSED_RS34720	COG0484	heat shock protein binding
PSED_RS34800	COG0235	Class ii aldolase
PSED_RS34820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PSED_RS34825	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PSED_RS34845	COG0406	alpha-ribazole phosphatase activity
PSED_RS34855	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PSED_RS34915	COG1793	dna ligase
PSED_RS34915	COG3285	dna ligase
PSED_RS34940	COG1414	Transcriptional regulator
PSED_RS34950	COG1309	transcriptional regulator
PSED_RS34985	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PSED_RS35000	COG1475	DNA binding
PSED_RS35030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PSED_RS35055	COG0617	tRNA 3'-terminal CCA addition
PSED_RS35055	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PSED_RS35055	COG0517	IMP dehydrogenase activity
PSED_RS35080	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PSED_RS35080	COG0512	Glutamine amidotransferase of anthranilate synthase
PSED_RS35115	COG0515	serine threonine protein kinase
PSED_RS35135	COG3511	phospholipase C
PSED_RS35140	COG0596	Alpha beta hydrolase
PSED_RS35200	COG0671	phosphoesterase, PA-phosphatase related
PSED_RS35205	COG0517	IMP dehydrogenase activity
PSED_RS35220	COG0501	Belongs to the peptidase M48B family
PSED_RS35270	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PSED_RS35270	COG0515	serine threonine protein kinase
PSED_RS35450	COG0154	amidase activity
PSED_RS35455	COG5002	protein histidine kinase activity
PSED_RS35455	COG0784	Response regulator, receiver
PSED_RS35455	COG2205	protein histidine kinase activity
PSED_RS35580	COG0515	serine threonine protein kinase
PSED_RS35585	COG0768	penicillin binding